format-version: 1.2 property_value: dc-title "Uber-anatomy ontology" xsd:string property_value: dc-description "Uberon is an integrated cross-species anatomy ontology representing a variety of entities classified according to traditional anatomical criteria such as structure, function and developmental lineage. The ontology includes comprehensive relationships to taxon-specific anatomical ontologies, allowing integration of functional, phenotype and expression data." xsd:string property_value: foaf-homepage "http://uberon.org" xsd:anyURI property_value: dc-publisher "http://obolibrary.org" xsd:anyURI property_value: dcterms-isReferencedBy "http://genomebiology.com/2012/13/1/R5" xsd:anyURI property_value: dcterms-isReferencedBy "http://www.ncbi.nlm.nih.gov/pubmed/22293552" xsd:anyURI property_value: dc-creator "Chris Mungall - https://orcid.org/0000-0002-6601-2165" xsd:string property_value: dc-creator "Melissa Haendel" xsd:string property_value: dc-creator "Alex Decechi" xsd:string property_value: dc-creator "Nizar Ibrahim" xsd:string property_value: dc-creator "Aurelie Comte" xsd:string property_value: dc-creator "Anne Niknejad" xsd:string property_value: dc-creator "Wasila Dahdul" xsd:string property_value: dc-creator "Erik Segerdell" xsd:string property_value: dc-creator "David Blackburn" xsd:string property_value: dc-contributor "Suzanna Lewis" xsd:string property_value: dc-contributor "Paula Mabee" xsd:string property_value: dc-contributor "George Gkoutos" xsd:string property_value: dc-contributor "Carlo Torniai" xsd:string property_value: dc-contributor "Maryann Martone" xsd:string property_value: dc-contributor "Bill Bug" xsd:string property_value: dc-contributor "Terry Hayamizu" xsd:string property_value: dc-contributor "Alexander Diehl" xsd:string property_value: dc-contributor "Ann Maglia" xsd:string property_value: dc-contributor "Terry Meehan" xsd:string property_value: dc-contributor "Yvonne Bradford" xsd:string property_value: dc-contributor "James Balhoff" xsd:string property_value: dc-contributor "Hilmar Lapp" xsd:string property_value: dc-contributor "David Osumi-Sutherland" xsd:string property_value: dc-contributor "Jonathan Bard" xsd:string property_value: dc-contributor "Duncan Davidson" xsd:string property_value: dc-contributor "David Hill" xsd:string property_value: dc-contributor "Rebecca Foulger" xsd:string property_value: dc-contributor "Shahim Essaid" xsd:string property_value: dc-contributor "Ceri Van Slyke" xsd:string property_value: dc-contributor "Paul Schofield" xsd:string property_value: dc-contributor "Robert Druzinsky" xsd:string property_value: dc-contributor "Brian K Hall" xsd:string property_value: dc-contributor "Frederic Bastian" xsd:string property_value: dc-contributor "Marc Robinson-Rechavi" xsd:string property_value: dc-contributor "Onard Mejino" xsd:string property_value: dc-contributor "Alan Ruttenberg" xsd:string property_value: dc-contributor "Cynthia Smith" xsd:string property_value: dc-contributor "Anna Anagnostopoulos" xsd:string property_value: dc-contributor "Sarah Whitcher Kansa - https://orcid.org/0000-0001-7920-5321" xsd:string property_value: dc-contributor "Phenoscape Project" xsd:string property_value: dc-contributor "Bgee Project - http://bgee.unil.ch" xsd:string property_value: dc-contributor "PATO Project" xsd:string property_value: dc-contributor "Gene Ontology Consortium" xsd:string property_value: dc-contributor "NIF Project - http://neuinfo.org/" xsd:string property_value: dc-source http://purl.obolibrary.org/obo/ma.owl property_value: dc-source http://purl.obolibrary.org/obo/fma.owl property_value: dc-source http://purl.obolibrary.org/obo/ehdaa2.owl property_value: dc-source http://purl.obolibrary.org/obo/emapa.owl property_value: dc-source http://purl.obolibrary.org/obo/bto.owl property_value: dc-source http://purl.obolibrary.org/obo/vhog.owl property_value: dc-source http://purl.obolibrary.org/obo/fbbt.owl property_value: dc-source http://purl.obolibrary.org/obo/wbbt.owl property_value: dc-source http://purl.obolibrary.org/obo/zfa.owl property_value: dc-source http://purl.obolibrary.org/obo/tao.owl property_value: dc-source http://purl.obolibrary.org/obo/vsao.owl property_value: dc-source http://purl.obolibrary.org/obo/aao.owl property_value: dc-source http://purl.obolibrary.org/obo/xao.owl property_value: dc-source http://purl.obolibrary.org/obo/caro.owl property_value: dc-source http://purl.obolibrary.org/obo/aeo.owl property_value: dc-source http://purl.obolibrary.org/obo/bila.owl property_value: dc-source http://www.e-lico.eu/public/kupo/kupo.owl property_value: dc-source http://en.wikipedia.org/wiki/ property_value: dc-source http://dbpedia.org property_value: dc-source http://palaeos.com property_value: dc-source http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-GrossAnatomy.owl property_value: dc-source http://purl.obolibrary.org/obo/go.owl property_value: dc-source http://purl.obolibrary.org/obo/hp.owl property_value: dc-source http://purl.obolibrary.org/obo/mp.owl property_value: dc-source http://purl.obolibrary.org/obo/cl.owl property_value: dc-source http://purl.obolibrary.org/obo/aba.owl property_value: dc-source http://www.brain-map.org property_value: dc-source http://braininfo.rprc.washington.edu/ property_value: dc-source http://pons.incf.org/wiki/Common_Upper_Mammalian_Brain_Ontology_%28Cumbo%29 property_value: dc-source "MESH" xsd:string property_value: dc-source "ISBN10:0073040584 Vertebrates, Kardong" xsd:string property_value: dc-source "ISBN:9780878932504 Developmental Biology" xsd:string property_value: dc-source "ISBN10:0471888893 Comparative Vertebrate Neuroanatomy: Evolution and Adaptation by Butler and Hodos" xsd:string property_value: dc-source "ISBN:0030229073 Invertebrate Zoology, Barnes" xsd:string property_value: dc-source "ISBN-10:0226313379 Fins into Limbs: Evolution, Development, and Transformation, Hall" xsd:string property_value: dc-source "ISBN-10:0443065837 Human embryology, Larsen" xsd:string property_value: dc-source "ISBN:9780120749034 The laboratory rat" xsd:string property_value: dc-source "PMID:16417468 Forgotten and novel aspects in pancreas development, Pieler and Chen" xsd:string property_value: dc-source "ISBN10:1588903958 Principles and practice of pediatric neurosurgery By A. Leland Albright, P. David Adelson, Ian F. Pollack" xsd:string property_value: dc-source "ISBN:0683400088 Stedman's Medical Dictionary" xsd:string property_value: dc-source "ISBN10:1588900649 Color Atlas and Textbook of Human Anatomy: Nervous system and sensory organs By Werner Kahle, Michael Frotscher" xsd:string property_value: dc-source "ISBN:9780397517251 Surgical anatomy of the hand and upper extremity. By James R. Doyle and Michael J. Botte" xsd:string property_value: dc-source "ISBN:9780674021839 The Tree of Life - Guillaume Lecointre, Herve Le Guyader" xsd:string property_value: dc-source "PMID:11433360 Placental development: lessons from mouse mutants" xsd:string property_value: dc-source "ISBN10:1607950324 Craniofacial Embryogenetics & Development, 2nd edition, Sperber" xsd:string property_value: dc-source "ISBN:978-0-12-369548-2 Principles of Developmental Genetics, Sally A Moody" xsd:string property_value: dc-source "ISBN10:0123813611 Comparative Anatomy and Histology: A Mouse and Human Atlas, Treuting and Dintzis" xsd:string property_value: dc-source "https://docs.google.com/document/d/1MnUgispgGfNQoezYzWzzGTnkAnI0gzRnJIwdip6MMtw/edit" xsd:anyURI property_value: dc-source "http://wiki.phenotypercn.org/wg/phenotypercn/index.php?title=Neural_Crest_Workshop" xsd:anyURI property_value: dc-source "https://docs.google.com/document/d/16JZOuH9sh_a8uIXA4cqg0Q1H6MV5yCj3-rhuKsZoV_U/edit" xsd:anyURI property_value: dc-source "https://docs.google.com/document/d/1cPWBqrl_Qy7XHEWFqtR_PgQX61yRkgGuLaiDpnEXxkE/edit" xsd:anyURI property_value: dc-source "https://docs.google.com/document/d/1r9kNPpFYGdu0SpJDLyFAVQczBlG0wAZCBMd18gG3Ot8/edit#" xsd:anyURI property_value: dc-source "https://docs.google.com/spreadsheet/ccc?key=0Aj8NJdyb-leqdDM0R3hTVTRHRExDVjRCSkZEbDc5N1E#gid=0" xsd:anyURI property_value: dc-source "http://wiki.phenotypercn.org/wiki/August_2012_Notes" xsd:anyURI property_value: doap-GitRepository "https://github.com/cmungall/uberon/" xsd:anyURI property_value: doap-SVNRepository "https://obo.svn.sourceforge.net/svnroot/obo/uberon/" xsd:anyURI property_value: doap-bug-database "http://purl.obolibrary.org/obo/uberon/tracker/" xsd:anyURI subsetdef: uberon_slim "Uberon slim - somewhat arbitrary subset that excludes obscure terms and deep compositional terms" subsetdef: vessel_or_tree "A term classified differently in FMA due to its treatment of branching structures - to be reviewed and revised by editors" subsetdef: grouping_class "Subset consisting of classes creating for grouping purposes" subsetdef: developmental_classification "developmental_classification" subsetdef: functional_classification "functional_classification" subsetdef: emapa_ehdaa2 "derived from the union of EHDAA2 and EMAPA - still to be checked" subsetdef: inconsistent_with_fma "classes that have some inconsistency with FMA" subsetdef: inherited_grouping_class "A grouping class that originates in two or more separate anatomical ontologies. Includes 'region of X' type terms" subsetdef: dubious_grouping "Indicates that subclasses in AOs may be inappropriately linked" subsetdef: unverified_taxonomic_grouping "Indicates that the class encompasses classes from other AOs that have not been verified" subsetdef: upper_level "abstract upper-level terms not directly useful for analysis" subsetdef: non_informative "abstract class brought in to group ontology classes but not informative" subsetdef: defined_by_ordinal_series "classes that are defined by relative position counting from first in a series of elements along an axis in an individual organism rather than by strict homology" subsetdef: vertebrate_core "core classes typically found across vertebrates. one purpose is to create a rough set of terms that could be used to start a new vertebrate AO" subsetdef: metazoa_core "core classes typically found across metazoa. one purpose is to create a rough set of terms that could be used to start a new metazoan AO. Note this subset is not yet fully fleshed out" subsetdef: major_organ "somewhat fuzzy grouping for analysis purposes, currently composed of something like: liver, heart, skeletal, kidney, bladder, brain, skin, mouth, esophagus, stomach, small intestine, large intestines, trachea nose, lungs, brain, spinal cord, peripheral nerves, kidneys, ureters, bladder, urethra, gonads" subsetdef: organ_slim "organs, excluding individual muscles and skeletal elements" subsetdef: upper_ontology_conflict "Terms in this subset group together terms from different anatomy ontologies that have conflicting upper ontology/CARO assignments. For example, in FMA the naris is immaterial and in ZFA it is an organism subdivision." subsetdef: disjointness_axiom_removed "A class which has a weakened disjointness axiom, to avoid inconsistency. These are kept separately in the uberon_disjoint_from_strict ontology." subsetdef: early_development "A class that represents an early developmental structure, like a blastocyst. This part of the ontology is undergoing review to remove inappropriate grouping classes." subsetdef: phenotype_rcn "A subset specifically created for the 2012 Phenotype RCN meeting. Includes some human-specific terms that may eventually be removed when they are adequately represented with part of relationships in FMA" subsetdef: cyclostome_subset "cyclostome structures" subsetdef: loose_concept "loose concept" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: ABBREVIATION "abbreviation" synonymtypedef: LATIN "latin term" synonymtypedef: PLURAL "plural term" synonymtypedef: DEVELOPMENTAL "developmental term" synonymtypedef: DUBIOUS "dubious or contested synonym" synonymtypedef: SENSU "taxonomic disambiguation" synonymtypedef: ATTRIBUTION_REQUIRED "expert consultation and attribution required" synonymtypedef: INCONSISTENT "indicates that a synonym is used in an inconsistent or confusing way, typically between species" synonymtypedef: DEPRECATED "A historic synonym, no longer encouraged" synonymtypedef: HOMOLOGY "a synonym made on the basis of a possibly homologous structure in another species" default-namespace: uberon treat-xrefs-as-equivalent: CARO treat-xrefs-as-equivalent: GO treat-xrefs-as-equivalent: BSPO treat-xrefs-as-equivalent: NIF_GrossAnatomy treat-xrefs-as-equivalent: BILA treat-xrefs-as-equivalent: OG treat-xrefs-as-equivalent: VSAO treat-xrefs-as-has-subclass: EMAPA treat-xrefs-as-has-subclass: EHDAA treat-xrefs-as-has-subclass: OGES treat-xrefs-as-has-subclass: EV treat-xrefs-as-has-subclass: SCTID treat-xrefs-as-has-subclass: ABA treat-xrefs-as-is_a: VHOG treat-xrefs-as-has-subclass: ncithesaurus treat-xrefs-as-reverse-genus-differentia: AAO part_of NCBITaxon:8292 treat-xrefs-as-reverse-genus-differentia: FBbt part_of NCBITaxon:7227 treat-xrefs-as-reverse-genus-differentia: FBdv part_of NCBITaxon:7227 treat-xrefs-as-reverse-genus-differentia: FMA part_of NCBITaxon:9606 treat-xrefs-as-reverse-genus-differentia: EHDAA2 part_of NCBITaxon:9606 treat-xrefs-as-reverse-genus-differentia: HsapDv part_of NCBITaxon:9606 treat-xrefs-as-reverse-genus-differentia: HAO part_of NCBITaxon:7399 treat-xrefs-as-reverse-genus-differentia: MA part_of NCBITaxon:10088 treat-xrefs-as-reverse-genus-differentia: MmusDv part_of NCBITaxon:10088 treat-xrefs-as-reverse-genus-differentia: MFO part_of NCBITaxon:8089 treat-xrefs-as-reverse-genus-differentia: OlatDv part_of NCBITaxon:8089 treat-xrefs-as-reverse-genus-differentia: SPD part_of NCBITaxon:6893 treat-xrefs-as-reverse-genus-differentia: TGMA part_of NCBITaxon:44484 treat-xrefs-as-reverse-genus-differentia: TADS part_of NCBITaxon:6939 treat-xrefs-as-reverse-genus-differentia: TAO part_of NCBITaxon:32443 treat-xrefs-as-reverse-genus-differentia: WBbt part_of NCBITaxon:6237 treat-xrefs-as-reverse-genus-differentia: XAO part_of NCBITaxon:8353 treat-xrefs-as-reverse-genus-differentia: ZFA part_of NCBITaxon:7954 treat-xrefs-as-reverse-genus-differentia: ZFS part_of NCBITaxon:7954 !remark: Uberon is an anatomical ontology covering metazoa. For more details, see http://uberon.org or http://genomebiology.com/2012/13/1/R5 ontology: uberon !import: http://purl.obolibrary.org/obo/go.owl !import: http://purl.obolibrary.org/obo/cl-basic.owl !import: http://purl.obolibrary.org/obo/ncbitaxon/subsets/taxslim-disjoint-over-in-taxon.owl idspace: Wikipedia http://en.wikipedia.org/wiki/ idspace: foaf http://xmlns.com/foaf/0.1 idspace: NIF_GrossAnatomy http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-GrossAnatomy.owl# idspace: SIO http://semanticscience.org/resource/SIO_ idspace: ncithesaurus http://ncicb.nci.nih.gov/xml/owl/EVS/ [Term] id: UBERON:0000000 name: processual entity def: "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity] subset: upper_level disjoint_from: UBERON:0001062 ! anatomical entity [Term] id: UBERON:0000002 name: uterine cervix def: "Lower, narrow portion of the uterus where it joins with the top end of the vagina." [Wikipedia:Cervix] subset: uberon_slim synonym: "canalis cervicis uteri" EXACT [FMA:TA] synonym: "cervical canal" EXACT [FMA:17740] synonym: "cervical canal of uterus" EXACT [FMA:17740] synonym: "neck of uterus" EXACT [FMA:17740] synonym: "uterine cervix" EXACT [FMA:17740] synonym: "cervix uteri" EXACT LATIN [EMAPA:29927] synonym: "caudal segment of uterus" EXACT [] synonym: "cervix" BROAD [EFO:0000979] xref: FMA:17740 ! Cervix of uterus xref: GAID:376 ! cervix xref: EMAPA:29927 ! cervix uteri xref: VHOG:0001359 ! uterine cervix xref: MA:0000392 ! uterine cervix xref: MAT:0000292 ! cervix xref: OpenCyc:Mx4rvVipEJwpEbGdrcN5Y29ycA xref: BTO:0001421 ! uterine cervix xref: BTO:0002249 ! cervical canal xref: EFO:0000979 ! cervix xref: OpenCyc:Mx4rvVipEJwpEbGdrcN5Y29ycA ! uterine cervix xref: MESH:A05.360.319.679.256 ! cervix uteri xref: EV:0100114 ! cervix is_a: UBERON:0001560 {source="FMA"} ! neck of organ relationship: continuous_with UBERON:0000996 ! vagina relationship: part_of UBERON:0000995 ! uterus synonym: "canalis cervicis uteri" EXACT LATIN [FMA:TA, FMA:17740] xref: SCTID:245494008 ! Entire cervical canal of uterus xref: ncithesaurus:Cervix ! cervix uteri xref: galen:CervixUteri ! cervix uteri property_value: external_definition "The narrow caudal end of the uterus that opens into the vagina. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001359", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/uterine+cervix", source="http://bgee.unil.ch/"} property_value: homology_notes "The evolution of mammals is associated with radical changes in their reproductive biology, particularly the structure and function of the female reproductive organs. These changes include the evolution of the uterus, cervix, vagina, placenta and specialized cell types associated with each of those structures.[well established][VHOG]" xsd:string {external_class="VHOG:0001359", ontology="VHOG", source="DOI:10.1098/rspb.2004.2848 Lynch VJ\, Roth JJ\, Takahashi K\, Dunn CW\, Nonaka DF\, Stopper GF\, Wagner GP\, Adaptive evolution of HoxA-11 and HoxA-13 at the origin of the uterus in mammals. Proceedings of the Royal Society of London\, Series B (2004)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "cervical" xsd:string xref: UMLS:C0007874 [Term] id: UBERON:0009853 name: body of uterus def: "that part of the uterus above the isthmus and below the orifices of the uterine tubes." [http://medical-dictionary.thefreedictionary.com/corpus+uteri] synonym: "uterine body" EXACT [FMA:17739] synonym: "uterine corpus" EXACT [FMA:17739] synonym: "corpus uteri" EXACT [UBERON:cjm] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000995 {source="FMA"} ! uterus xref: FMA:17739 ! body of uterus xref: ncithesaurus:Corpus_Uteri xref: SCTID:279878007 ! Entire corpus uteri xref: EFO:0000382 ! corpus uteri xref: UMLS:C0227813 [Term] id: UBERON:0000003 name: naris def: "Orifice of the olfactory system. The naris is the route by which odorants enter the olfactory system[MAH]." [UBERON:MAH] comment: consistency notes: we have classified this as an orifice, according to FMA. Note that in FMA, orifices are immaterial entities, but in ZFA this is a surface structure. Taxon notes: in actinopterygians, both pairs of nares are external. In tetrapods, the exhalant empties into the buccal cavity subset: uberon_slim subset: vertebrate_core subset: upper_ontology_conflict xref: AAO:0000311 ! naris xref: EHDAA:9083 ! naris xref: VHOG:0000663 ! naris xref: MA:0000282 ! naris xref: galen:Naris ! naris xref: EHDAA2:0001225 ! naris xref: EMAPA:17847 ! naris is_a: UBERON:0000161 {source="FMA"} ! orifice intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0005725 ! olfactory system relationship: part_of UBERON:0000033 {source="ZFA"} ! head relationship: in_lateral_side_of UBERON:0000033 {gci_relation="part_of", gci_filler="NCBITaxon:7776", notes="hagfish have median nostril"} ! head xref: SCTID:272650008 ! Naris, entire, anterior or posterior property_value: external_definition "One of paired external openings of the nasal chamber.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000311", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "Naris refer to the external and interior naris (choana) of tetrapods, and to anterior and posterior naris of zebrafish. It seems now accepted that the structure is homologous: The choana, a unique 'internal nostril' opening from the nasal sac into the roof of the mouth, is a key part of the tetrapod (land vertebrate) respiratory system. It was the first component of the tetrapod body plan to evolve, well before the origin of limbs, and is therefore crucial to our understanding of the beginning of the fish-tetrapod transition. (...) Here we present new material of Kenichthys, a 395-million-year-old fossil fish from China, that provides direct evidence for the origin of the choana and establishes its homology: it is indeed a displaced posterior external nostril that, during a brief transitional stage illustrated by Kenichthys, separated the maxilla from the premaxilla.[well established][VHOG]" xsd:string {external_class="VHOG:0000663", ontology="VHOG", source="doi:10.1038/nature02843 Zhu M\, Ahlberg PE\, The origin of the internal nostril in tetrapodes. Nature (2004)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005928 ! external naris name: external naris def: "Surface structure that provides one of the small external openings of the head that give passage to air for breathing." [OMD:nostril, Wikipedia:Nostril] comment: Fish have two pairs of external nostrils. subset: vertebrate_core synonym: "external nares" EXACT PLURAL [] synonym: "anterior naris" RELATED [ZFA:0001427] synonym: "nostril" EXACT [XAO:0003033, FMA:59645] synonym: "blowhole" NARROW [Wikipedia:Blowhole_(anatomy)] synonym: "naris" BROAD [ZFA:0000550] xref: TAO:0000550 ! naris xref: ZFA:0000550 ! naris xref: FMA:59645 ! External naris xref: MA:0001320 ! external naris xref: XAO:0003033 ! nostril xref: ncithesaurus:Nostril ! Nostril xref: AAO:0000024 ! apertura_nasalis_externa xref: OpenCyc:Mx4rvViCLpwpEbGdrcN5Y29ycA ! nostril xref: VHOG:0000544 ! external naris xref: EHDAA2:0001275 ! nostril xref: EMAPA:17848 ! external of naris xref: EHDAA:9085 ! external of naris xref: AAO:0010358 ! nostril xref: AAO:0000983 ! external naris is_a: UBERON:0003102 {source="ZFA"} ! surface structure is_a: UBERON:0000003 {source="MA"} ! naris relationship: part_of UBERON:0000004 ! olfactory apparatus relationship: has_function_in GO:0007585 ! breathing xref: SCTID:276165005 ! Entire anterior naris property_value: external_definition "Hole on the nasal capsule that connects the nasal cavity with the exterior.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000024", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass nasal opening (AAO:0000316)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000024", date_retrieved="2012-06-20"} synonym: "anterior nares" RELATED PLURAL [VHOG:0000544] property_value: homology_notes "In a tetrapod, the nasal sac has an external naris (homologous with the anterior naris of the fish) (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000544", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.257 and Figure 7.27", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0595944 [Term] id: UBERON:0010893 alt_id: UBERON:0012123 name: median external naris synonym: "median anterior naris" EXACT [] synonym: "median nostril" EXACT [] synonym: "nasohypophysial opening" EXACT [http://tolweb.org/Hyperoartia] intersection_of: UBERON:0005928 ! external naris intersection_of: in_median_plane_of UBERON:0000033 ! head relationship: present_in_taxon NCBITaxon:7762 subset: cyclostome_subset [Term] id: UBERON:0010425 ! internal naris name: internal naris synonym: "choana" EXACT [] synonym: "internal nostril" RELATED [] is_a: UBERON:0000003 {source="MA"} ! naris property_value: has_relational_adjective "choanal" xsd:string [Term] id: UBERON:0010426 name: oropharyngeal choana def: "opening/conduit between the nasal cavity and the oropharynx via the roof of the mouth." [UBERON:cjm] comment: Taxon notes: Aves. Function notes: has function in pressure equalization in birds that fly to high altitudes synonym: "oropharyngeal naris" EXACT [] synonym: "choana of oropharynx" EXACT [] synonym: "palatal choana" EXACT [] synonym: "palatal cleft" RELATED [] synonym: "cleft palate" RELATED [] synonym: "apertura nasalis interna" RELATED [AAO:0000025] is_a: UBERON:0010425 ! internal naris relationship: adjacent_to UBERON:0001729 ! oropharynx relationship: part_of UBERON:0001716 ! secondary palate xref: AAO:0000025 ! apertura nasalis interna property_value: external_definition "Hole on the nasal capsule that connects the nasal and buccal cavites.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000025", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass nasal opening (AAO:0000316)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000025", date_retrieved="2012-06-20"} [Term] id: UBERON:0004771 ! posterior nasal aperture name: posterior nasal aperture def: "Opening/conduit between the nasal cavity and the nasopharynx[AAO] The choanae are separated by the vomer[WP]." [AAO:0000093, Wikipedia:Posterior_nasal_apertures] comment: Fish don't have choanae, instead they have two pairs of external nostrils[WP] In addition to tetrapods, the lungfish has internal nostrils too. TODO: check part_of vs adjacent_to nasal cavity. In tetrapods the exhalant nostril (choana) empties into the buccal cavity. synonym: "choana" BROAD [XAO:0000277, Wikipedia:Choane] synonym: "internal naris" BROAD [MA:0001323] synonym: "nasopharyngeal naris" RELATED [] xref: AAO:0000093 ! choana xref: XAO:0000277 ! choana xref: FMA:53143 ! posterior nasal aperture xref: VHOG:0000545 ! choana xref: EHDAA2:0000242 ! choana xref: EHDAA:7842 ! choana xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/87/Gray855.png/200px-Gray855.png xref: MA:0001323 ! internal naris is_a: UBERON:0010425 ! internal naris intersection_of: UBERON:0000003 ! naris intersection_of: adjacent_to UBERON:0001728 ! nasopharynx intersection_of: located_in UBERON:0001707 ! nasal cavity relationship: part_of UBERON:0003128 ! cranium xref: SCTID:244507001 ! Entire choana xref: http://upload.wikimedia.org/wikipedia/commons/8/87/Gray855.png property_value: external_definition "Opening between the nasal cavity and the nasopharynx.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000093", date_retrieved="2012-06-20", source="AAO:LAP"} synonym: "choanae" RELATED PLURAL [VHOG:0000545] synonym: "posterior naris" RELATED [VHOG:0000545] property_value: external_definition "One of the paired openings from the nasal cavities into the pharynx. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-6, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000545", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The choana, a unique 'internal nostril' opening from the nasal sac into the roof of the mouth, is a key part of the tetrapod (land vertebrate) respiratory system. It was the first component of the tetrapod body plan to evolve, well before the origin of limbs, and is therefore crucial to our understanding of the beginning of the fish-tetrapod transition. (...) Here we present new material of Kenichthys, a 395-million-year-old fossil fish from China, that provides direct evidence for the origin of the choana and establishes its homology: it is indeed a displaced posterior external nostril that, during a brief transitional stage illustrated by Kenichthys, separated the maxilla from the premaxilla.[well established][VHOG]" xsd:string {external_class="VHOG:0000545", ontology="VHOG", source="doi:10.1038/nature02843 Zhu M\, Ahlberg PE\, The origin of the internal nostril in tetrapodes. Nature (2004)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005931 name: primary choana def: "initial opening of the nasal pits and olfactory sac of the embryo into the rostral part of the primordial oronasal cavity, before the formation of the secondary palate." [http://www.drugs.com/dict/primary-choana.html] comment: TODO - check. MA says part_of external naris. xref: MA:0001322 ! primary choana xref: EMAPA:17851 ! primary choana xref: EHDAA:9087 ! primary choana is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0005928 ! external naris [Term] id: UBERON:0002109 name: pair of nares def: "Pair of nostrils." [Wikipedia:Nares] comment: Note this is a "set of anatomical planes" in FMA subset: uberon_slim synonym: "nares" RELATED [] synonym: "nares set" EXACT [] synonym: "nostrils" EXACT [] synonym: "pair of nostrils" EXACT [] xref: FMA:72005 ! Set of nares xref: OpenCyc:Mx4rvViCLpwpEbGdrcN5Y29ycA is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0000004 ! olfactory apparatus relationship: never_in_taxon NCBITaxon:7745 {source="http://webs.lander.edu/rsfox/invertebrates/ammocoetes.html"} ! Petromyzontiformes synonym: "set of nares" RELATED [FMA:72005] [Term] id: UBERON:0000402 name: nasal vestibule def: "The nasal vestibule is the most anterior part of the nasal cavity. It's enclosed by the cartilages of nose and lined by the same epithelium of the skin. The other part of the nasal cavity, which is lined by the respiratory epithelium, is called nasal cavity proper. [WP,unvetted]." [Wikipedia:Nasal_vestibule] synonym: "vestibular part of nasal cavity" EXACT [FMA:59644] synonym: "vestibulum nasale" RELATED [BTO:0001761] synonym: "vestibulum nasi" RELATED [BTO:0001761] xref: BTO:0001761 xref: FMA:59644 ! Nasal vestibule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7c/Gray994.png/200px-Gray994.png is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001707 ! nasal cavity xref: SCTID:278940000 ! Entire nasal vestibule synonym: "vestibulum nasi" RELATED LATIN [Wikipedia:Nasal_vestibule] xref: http://upload.wikimedia.org/wikipedia/commons/7/7c/Gray994.png [Term] id: UBERON:0004110 name: midnasal cavity def: "includes the cavity between the nares and the choanae." [HP:0010641] is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001707 ! nasal cavity relationship: adjacent_to UBERON:0004771 ! posterior nasal aperture relationship: adjacent_to UBERON:0005928 ! external naris [Term] id: UBERON:0005725 ! olfactory system name: olfactory system def: "The olfactory system is the sensory system used for olfaction, or the sense of smell. Most mammals and reptiles have two distinct parts to their olfactory system: a main olfactory system and an accessory olfactory system. The main olfactory system detects volatile, airborne substances, while the accessory olfactory system senses fluid-phase stimuli. Behavioral evidence indicates that most often, the stimuli detected by the accessory olfactory system are pheromones. The olfactory system is often spoken of along with the gustatory system as the chemosensory senses because both transduce chemical signals into perception[WP]." [Wikipedia:Olfactory_system] comment: In mammals, the main olfactory system detects odorants that are inhaled through the nose, where they contact the main olfactory epithelium, which contains various olfactory receptors. These olfactory receptors are membrane proteins of bipolar olfactory receptor neurons in the olfactory epithelium. Rather than binding specific ligands like most receptors, olfactory receptors display affinity for a range of odor molecules. Olfactory neurons transduce receptor activation into electrical signals in neurons. The signals travel along the olfactory nerve, which belongs to the peripheral nervous system. This nerve terminates in the olfactory bulb, which belongs to the central nervous system. The complex set of olfactory receptors on different olfactory neurons can distinguish a new odor from the background environmental odors and determine the concentration of the odor // Editor note: consider splitting into main and accessory. See also: vomeronasal organ // note we make the relationship to nervous system 'overlaps', as the olfactory system includes e.g. apertures in the cranium that are not part of the nervous system subset: vertebrate_core xref: ZFA:0001149 ! olfactory system xref: AAO:0000334 ! olfactory_system xref: BILA:0000144 ! olfactory system xref: FMA:7190 ! Olfactory system xref: MA:0002445 ! olfactory system xref: TAO:0001149 ! olfactory system xref: EFO:0001973 ! olfactory system xref: OpenCyc:Mx4rvViw75wpEbGdrcN5Y29ycA ! olfactory system xref: NIF_GrossAnatomy:nlx_anat_090806 ! Olfactory system xref: XAO:0003196 ! olfactory system intersection_of: UBERON:0001032 ! sensory system intersection_of: capable_of GO:0007608 ! sensory perception of smell relationship: overlaps UBERON:0001016 ! nervous system xref: AAO:0000978 ! olfactory system xref: SCTID:362290002 ! Entire olfactory system xref: ncithesaurus:Olfactory_System ! olfactory system property_value: external_definition "The sensory system used for olfaction (the sense of smell).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000978", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C0228065 [Term] id: UBERON:0007827 name: external nose def: "Subdivision of face, the exterior of the nose, which consists of a root, dorsum, tip, columella, and right and left alae." [FMA:59515] synonym: "nose" RELATED [] xref: FMA:59515 ! external nose is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0000004 {source="FMA"} ! olfactory apparatus xref: ncithesaurus:External_Nose ! External Nose xref: SCTID:265785009 ! Entire external nose xref: UMLS:C0458561 [Term] id: UBERON:0000004 name: olfactory apparatus def: "a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration in conjunction with the mouth. Behind the nose are the olfactory mucosa and the sinuses. Behind the nasal cavity, air next passes through the pharynx, shared with the digestive system, and then into the rest of the respiratory system. In humans, the nose is located centrally on the face; on most other mammals, it is on the upper tip of the snout[WP]. GO: The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [Wikipedia:Nose] comment: TODO - distinguish generic olfactory apparatus from nose; we have olfactory organ for the generic organ - add new class 'olfactory structure'? subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "nose" EXACT [] synonym: "peripheral olfactory organ" EXACT [] synonym: "proboscis" RELATED [] synonym: "nasal sac" EXACT SENSU [ZFA:0000047] xref: BTO:0000840 xref: EFO:0000828 ! nose xref: EHDAA:1502 ! nose xref: FMA:46472 ! Nose xref: GAID:77 ! nose xref: MA:0000281 ! nose xref: MAT:0000139 ! nose xref: MIAA:0000139 ! nose xref: OpenCyc:Mx4rvViCbJwpEbGdrcN5Y29ycA xref: TAO:0000047 ! peripheral olfactory organ xref: ZFA:0000047 ! peripheral olfactory organ xref: ncithesaurus:Nose ! Nose xref: galen:Nose ! nose xref: OpenCyc:Mx4rvViCbJwpEbGdrcN5Y29ycA ! nose xref: EHDAA2:0001274 ! nose xref: EMAPA:16542 ! nose xref: MESH:A01.456.505.733 ! nose xref: EV:0100037 ! nose xref: EV:0100370 ! olfactory apparatus is_a: UBERON:0002268 ! olfactory organ relationship: develops_from UBERON:0003050 ! olfactory placode relationship: has_function_in GO:0007608 ! sensory perception of smell relationship: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0004089 ! midface xref: SCTID:181195007 ! Entire nose synonym: "Nasus" RELATED LATIN [Wikipedia:Nose] xref: http://upload.wikimedia.org/wikipedia/commons/d/d0/Canine-nose.jpg xref: UMLS:C0028429 [Term] id: UBERON:0002268 ! olfactory organ name: olfactory organ comment: note - fma general anatomical term. xao has no subtypes (but Johnstons organ develops from this). An olfactory organ overlaps with the olfactory system, because some parts of the nose (e.g. nasal skeleton) are parts of the skeletal system, which is spatially disjoint subset: functional_classification synonym: "olfactory neuroepithelium" RELATED [BTO:0001772] synonym: "organ olfactus" RELATED [BTO:0001772] synonym: "organum olfactorium" RELATED [BTO:0001772] xref: FMA:77659 ! Olfactory organ xref: VHOG:0000287 ! olfactory organ xref: XAO:0000273 ! olfactory organ xref: BTO:0001772 ! olfactory organ intersection_of: UBERON:0000020 ! sense organ intersection_of: has_function_in GO:0007608 ! sensory perception of smell relationship: overlaps UBERON:0005725 ! olfactory system xref: AAO:0010180 ! olfactory organ [Term] id: UBERON:0001707 name: nasal cavity def: "a large air filled space above and behind the nose in the middle of the face[WP]." [Wikipedia:Nasal_cavity] comment: the cavity includes and starts at the nares and reaches all the way through to the and includes the choanae, the posterior nasal apertures[HP] subset: uberon_slim subset: vertebrate_core synonym: "cavity of nose" EXACT [] synonym: "nasal pit" RELATED [] synonym: "olfactory cavity" RELATED [] synonym: "olfactory pit" RELATED INCONSISTENT [ZFA:0000130] synonym: "nasal fossa" EXACT [Wikipedia:Nasal_cavity] synonym: "nasal canal" EXACT [ZFA:0000130] synonym: "cavitas nasalis" RELATED [BTO:0002096] synonym: "cavitas nasi" RELATED [BTO:0002096] xref: AAO:0000314 ! nasal_cavity xref: EHDAA:6801 ! nasal cavity xref: FMA:54378 ! Nasal cavity xref: GAID:350 ! nasal cavity xref: VHOG:0000271 ! nasal cavity xref: MA:0000284 ! nasal cavity xref: TAO:0000130 ! olfactory pit xref: ZFA:0000130 ! olfactory pit xref: ncithesaurus:Nasal_Cavity ! Nasal Cavity xref: BTO:0002096 ! nasal cavity xref: EHDAA2:0001226 ! nasal cavity xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d4/Illu01_head_neck.jpg/200px-Illu01_head_neck.jpg xref: EMAPA:17604 ! nasal cavity xref: MESH:A04.531.449 ! nasal cavity is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0000004 {source="MA"} ! olfactory apparatus relationship: part_of UBERON:0001557 {source="MA"} ! upper respiratory tract relationship: develops_from UBERON:0005870 ! olfactory pit xref: SCTID:263481003 ! Entire nasal cavity synonym: "cavum nasi; cavitas nasi" RELATED LATIN [Wikipedia:Nasal_cavity] xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg property_value: external_definition "Saclike space internal to the nasal capsule lined by respiratory and sensory epithelium and glandular tissue.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000314", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: homology_notes "Despite significant modification to the nasal cavity within Archosauria and its extreme hypertrophy and supraorbital development in Lambeosaurinae, the neural olfactory system and the olfactory region of the nasal cavity proper retain their plesiomorphic positions and associations, suggesting that this system is highly conserved in vertebrate evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0000271", ontology="VHOG", source="DOI:10.1666/0094-8373(2006)032[0109:NCHACC]2.0.CO;2 Evans DC\, Nasal cavity homologies and cranial crest function in lambeosaurine dinosaurs. Paleobiology (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0027423 [Term] id: UBERON:0005870 ! olfactory pit name: olfactory pit def: "An indentation of the olfactory placode which ends when the pits hollows out to form the nasopharynx[GO]." [Wikipedia:Nasal_pit, GO:0060166] comment: we represent the relationship as develops from, though in fact the pit is formed as an indentation in the placode synonym: "nasal pit" EXACT [XAO:0000275] xref: EHDAA2:0001295 ! olfactory pit xref: EHDAA:4772 ! olfactory pit xref: EMAPA:16800 ! olfactory pit xref: XAO:0000275 ! nasal pit xref: XAO:0004073 ! olfactory pit xref: EFO:0003496 ! olfactory pit is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000004 {source="EMAPA"} ! olfactory apparatus relationship: develops_from UBERON:0003050 {source="XAO:0000275 nasal pit"} ! olfactory placode xref: AAO:0011068 ! nasal pit xref: SCTID:361485001 ! Olfactory pit property_value: external_definition "By the upgrowth of the surrounding parts the olfactory areas are converted into pits, the nasal pits or olfactory pits, which indent the fronto-nasal process and divide it into a medial and two lateral nasal processes[Wikipedia:Nasal_pit]." xsd:string {source="Wikipedia:Nasal_pit"} [Term] id: UBERON:0005384 name: nasal cavity epithelium synonym: "nasal mucosa" RELATED [] synonym: "nasal epithelium" EXACT [FMA:63140] xref: MA:0001324 ! nasal cavity epithelium xref: EHDAA:6803 ! epithelium xref: VHOG:0000501 ! nasal epithelium xref: EHDAA2:0001227 ! nasal cavity epithelium xref: FMA:63140 ! nasal epithelium xref: ncithesaurus:Nasal_Cavity_Epithelium ! Nasal Cavity Epithelium xref: EMAPA:17605 ! epithelium of nasal cavity intersection_of: UBERON:0000483 ! epithelium intersection_of: located_in UBERON:0001707 ! nasal cavity relationship: part_of UBERON:0001826 {source="FMA"} ! nasal cavity mucosa def: "An epithelium that is part of a nasal cavity." [OBOL:automatic] xref: UMLS:C1709151 [Term] id: UBERON:0005386 name: olfactory mucosa def: "That portion of the nasal mucosa containing the sensory endings for olfaction; the organ of smell[GAID]. The olfactory mucosa is located in the upper region of the nasal cavity and is made up of the olfactory epithelium and the underlying lamina propria, connective tissue containing fibroblasts, blood vessels, Bowman's glands and bundles of fine axons from the olfactory neurons. The mucus protects the olfactory epithelium and allows odors to dissolve so that they can be detected by olfactory receptor neurons. Electron microscopy studies show that Bowman's glands contain cells with large secretory vesicles. The exact composition of the secretions from Bowman's glands is unclear, but there is evidence that Bowman's glands do not produce odorant binding protein[WP]." [Wikipedia:Olfactory_mucosa, GAID:303] comment: note uberon uses the term 'mucosa' as 'portion of mucosa', thus the relationship is subclass, not part_of synonym: "olfactory zone of nasal mucosa" EXACT [FMA:77199] synonym: "olfactory area of nasal mucosa" EXACT [FMA:77199] synonym: "olfactory part of nasal mucosa" EXACT [FMA:77199] xref: FMA:77199 ! olfactory zone of nasal mucosa xref: GAID:303 ! olfactory mucosa xref: MESH:A04.531.520.573 ! olfactory mucosa relationship: has_part UBERON:0005384 ! nasal cavity epithelium is_a: UBERON:0001826 ! nasal cavity mucosa synonym: "pars olfactoria tunicae mucosae nasi" EXACT LATIN [FMA:TA, FMA:77199] xref: ncithesaurus:Olfactory_Mucosa ! Olfactory Mucosa synonym: "pars olfactoria tunicae mucosae nasi" RELATED LATIN [Wikipedia:Olfactory_mucosa] xref: UMLS:C0028937 [Term] id: UBERON:0001826 ! nasal cavity mucosa name: nasal cavity mucosa def: "the mucous membrane that lines the nasal cavity[MP]." [MP:0002238] comment: TODO - check lining vs part of. split olfactory and nasal mucosa? synonym: "mucous membrane of nose" EXACT [FMA:59684] synonym: "nasal mucosa" RELATED [] synonym: "mucosa of nose" EXACT [FMA:59684] xref: BTO:0000912 ! nasal mucosa xref: FMA:59684 ! Mucosa of nose xref: GAID:302 ! nasal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000004 ! olfactory apparatus relationship: located_in UBERON:0001707 ! nasal cavity synonym: "tunica mucosa nasi" EXACT LATIN [FMA:TA, FMA:59684] synonym: "tunica mucosa nasalis" EXACT [] xref: SCTID:310211009 ! Entire mucous membrane of nose [Term] id: UBERON:0003729 name: mouth mucosa def: "the mucous membrane epithelium of the mouth. It can be divided into three categories: masticatory, lining, and specialized." [Wikipedia:Oral_mucosa] comment: Usage notes: this is defined as any mucous membrane of the mouth - including palate, lips, uvula, etc. ncit split mouth/oral mucosa into lip and buccal. In future we may split into masticatory/keratinized (gingiva + hard palate) vs lining/non-keratinized (lips, cheeks, floor of mouth, soft palate). FMA distinguishes between mucosa of mouth and region of mouth (the latter including the buccal mucosa) synonym: "buccal mucosa" RELATED [GAID:951] synonym: "mouth mucosa" EXACT [FMA:59660] synonym: "mucous membrane of mouth" EXACT [FMA:59660] synonym: "oral mucosa" RELATED [GAID:951] synonym: "oral part of viscerocranial mucosa" EXACT [FMA:59660] synonym: "mouth mucous membrane" EXACT [OBOL:accepted] synonym: "mouth organ mucosa" EXACT [OBOL:accepted] synonym: "mucosa of mouth" EXACT [OBOL:accepted] synonym: "oral mucous membrane" EXACT [] synonym: "mucosal lining of mouth" RELATED [MA:0002794] xref: FMA:59660 ! Mucosa of mouth xref: GAID:951 ! mouth mucosa xref: MA:0002794 ! oral mucosa xref: BTO:0002860 ! oral mucosa xref: MESH:A10.615.550.599 ! mouth mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000165 ! mouth relationship: continuous_with UBERON:0000355 ! pharyngeal mucosa relationship: continuous_with UBERON:0001458 ! skin of lip synonym: "tunica mucosa oris" EXACT LATIN [FMA:TA, FMA:59660] xref: ncithesaurus:Oral_Mucosa ! Oral Mucosa synonym: "tunica mucosa oris" RELATED LATIN [Wikipedia:Oral_mucosa] xref: UMLS:C0026639 [Term] id: UBERON:0006956 name: buccal mucosa def: "The inner lining of the cheeks and lips." [Medical_Dictionary:http://www.medterms.com/] xref: FMA:59785 ! buccal mucosa xref: BTO:0003833 ! buccal mucosa is_a: UBERON:0000344 ! mucosa relationship: part_of UBERON:0003729 ! mouth mucosa relationship: part_of UBERON:0001567 ! cheek xref: ncithesaurus:Buccal_Mucosa ! Buccal Mucosa xref: SCTID:16811007 ! Buccal mucosa xref: UMLS:C1578559 [Term] id: UBERON:0002424 name: oral epithelium def: "Epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues" [UBERON:cjm] comment: Editor note: consider including separate class for developmental structure (adult human is stratified; in EHDAA2 is unilaminar). Development notes: the avian oral epithelium has the developmental capacity to initiate tooth developmental programs with underlying grafts of non-avian oral ectomesenchyme [PMID:16488870] subset: vertebrate_core synonym: "epithelium of mucosa of mouth" EXACT [FMA:265152] synonym: "epithelium of oral mucosa" EXACT [FMA:265152] xref: EHDAA:2187 ! oral epithelium xref: VHOG:0000187 ! oral epithelium xref: MA:0000344 ! oral epithelium xref: ZFA:0000816 ! oral epithelium xref: BTO:0001775 ! oral epithelium xref: EHDAA2:0001325 ! oral epithelium xref: XAO:0003201 ! oral epithelium xref: EMAPA:16839 ! oral epithelium of oral region xref: EMAPA:26942 ! oral epithelium of mucosa of oral region is_a: UBERON:0006915 {source="FMA", gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! stratified squamous epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003729 ! mouth mucosa relationship: adjacent_to UBERON:0000167 {source="AAO-modified"} ! oral cavity xref: AAO:0010357 ! oral epithelium xref: ncithesaurus:Oral_Cavity_Epithelium ! oral cavity epithelium xref: TAO:0000816 ! oral epithelium xref: FMA:265152 ! epithelium of mucosa of mouth property_value: external_definition "The epithelium that lines the oral cavity. The oral epithelium epithelial cells with many short microvilli as well as mucous cells, rodlet cells and taste buds[ZFIN:ZDB-PUB-060921-12, ZFIN:ZDB-PUB-091204-24]." xsd:string {source="ZFA:0000816"} xref: UMLS:C1709332 [Term] id: UBERON:0000176 name: oronasal secretion def: "Oronasal secretion is a bodily fluid secreted from the body via the mouth or nose." [ENVO:02000035] xref: ENVO:02000035 is_a: UBERON:0000463 ! portion of organism substance relationship: secreted_by UBERON:0001826 ! nasal cavity mucosa [Term] id: UBERON:0001997 name: olfactory epithelium alt_id: UBERON:0004853 def: "Epithelium inside the nasal cavity that is responsible for detecting odors[WP]." [Wikipedia:Olfactory_epithelium, ZFIN:curator] comment: Genes: V1Rs, Trpc2 present in lamprey // See also: FMA:77199 ! olfactory zone of nasal mucosa subset: uberon_slim subset: vertebrate_core synonym: "nasal epithelium" RELATED [] synonym: "nasal sensory epithelium" RELATED [] synonym: "olfactory sensory epithelium" EXACT [] synonym: "sensory olfactory epithelium" EXACT [] synonym: "nasal cavity olfactory epithelium" EXACT [MA:0001325] synonym: "olfactory mucosa" RELATED [GAID:303] synonym: "olfactory membrane" EXACT [NIF_GrossAnatomy:birnlex_2703] xref: BTO:0000108 xref: FMA:64803 ! Olfactory epithelium xref: VHOG:0000985 ! olfactory epithelium xref: MAT:0000445 ! olfactory epithelium xref: NIF_GrossAnatomy:birnlex_2703 ! Olfactory epithelium xref: TAO:0000554 ! olfactory epithelium xref: ZFA:0000554 ! olfactory epithelium xref: ncithesaurus:Olfactory_Epithelium ! Olfactory Epithelium xref: EFO:0001972 ! olfactory epithelium xref: MA:0001325 ! nasal cavity olfactory epithelium xref: EHDAA2:0001228 ! nasal cavity olfactory epithelium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray857.png/200px-Gray857.png xref: EMAPA:17606 ! olfactory xref: EHDAA:4774 ! nasal epithelium is_a: UBERON:0006934 ! sensory epithelium is_a: UBERON:0010499 {source="FMA", notes="check for other species"} ! pseudostratified ciliated columnar epithelium relationship: part_of UBERON:0001826 {source="FMA"} ! nasal cavity mucosa relationship: part_of UBERON:0000010 ! peripheral nervous system relationship: develops_from UBERON:0003050 ! olfactory placode relationship: has_part CL:0000207 {source="FMA"} ! olfactory receptor cell relationship: has_part CL:0000853 {source="FMA"} ! olfactory epithelial support cell relationship: has_function_in GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell xref: AAO:0010158 ! olfactory epithelium xref: SCTID:37623003 ! Olfactory sensory epithelium xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray857.png property_value: external_definition "Sensory lining of the medial wall, roof and anterior aspects of the main olfactory cavity (cavum principale).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010158", date_retrieved="2012-06-20", source="AAO:DSM"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of principal cavity (AAO:0000992)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010158", date_retrieved="2012-06-20"} xref: UMLS:C0599332 [Term] id: UBERON:0005385 name: nasal cavity respiratory epithelium xref: MA:0001326 ! nasal cavity respiratory epithelium xref: EHDAA2:0001230 ! nasal cavity respiratory epithelium xref: EHDAA:6807 ! respiratory is_a: UBERON:0005384 ! nasal cavity epithelium xref: ncithesaurus:Nasal_Cavity_Respiratory_Epithelium ! Nasal Cavity Respiratory Epithelium xref: UMLS:C1709152 [Term] id: UBERON:0000005 name: chemosensory organ subset: uberon_slim subset: functional_classification synonym: "chemosensory sensory organ" EXACT [FBbt:00005157] xref: FBbt:00005157 ! chemosensory sensory organ intersection_of: UBERON:0000020 ! sense organ intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus relationship: part_of UBERON:0005726 ! chemosensory system relationship: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0005726 ! chemosensory system name: chemosensory system xref: BILA:0000139 ! chemosensory system intersection_of: UBERON:0001032 ! sensory system intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus [Term] id: UBERON:0001728 name: nasopharynx def: "uppermost part of the pharynx. It extends from the base of the skull to the upper surface of the soft palate; it differs from the oral and laryngeal parts of the pharynx in that its cavity always remains patent (open)[WP]. In front it communicates through the choanae with the nasal cavities. On its lateral wall is the pharyngeal ostium of the auditory tube, somewhat triangular in shape, and bounded behind by a firm prominence, the torus tubarius or cushion, caused by the medial end of the cartilage of the tube which elevates the mucous membrane." [Wikipedia:Nasopharynx] subset: uberon_slim synonym: "nasal part of pharynx" EXACT [] synonym: "rhinopharynx" EXACT [] synonym: "epipharynx" RELATED [Wikipedia:Pharynx] synonym: "Nasenrachenraum" RELATED [BTO:0000662] xref: BTO:0000662 xref: EHDAA:7086 ! nasopharynx xref: FMA:54878 ! Nasopharynx xref: GAID:339 ! nasopharynx xref: VHOG:0000375 ! nasopharynx xref: MA:0000443 ! nasopharynx xref: MAT:0000447 ! nasopharynx xref: ncithesaurus:Nasopharynx ! Nasopharynx xref: OpenCyc:Mx4rwUPoDJwpEbGdrcN5Y29ycA ! nasopharynx xref: EHDAA2:0001239 ! nasopharynx xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Illu_pharynx.jpg/200px-Illu_pharynx.jpg xref: EMAPA:25092 ! nasopharynx of nose xref: EMAPA:17670 ! nasopharynx of upper of respiratory tract xref: MESH:A03.867.557 ! nasopharynx xref: EV:0100066 ! nasopharynx is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001557 ! upper respiratory tract xref: SCTID:181200003 ! Entire nasopharynx synonym: "pars nasalis pharyngis" RELATED LATIN [Wikipedia:Nasopharynx] xref: http://upload.wikimedia.org/wikipedia/commons/4/4a/Illu_pharynx.jpg property_value: external_definition "The uppermost of the three regions of the throat (pharynx), situated behind the nasal cavity and extending from the posterior nares to the level above the soft palate. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000375", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/nasopharynx", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "nasopharyngeal" xsd:string xref: UMLS:C0027442 [Term] id: UBERON:0001729 name: oropharynx def: "The Oropharynx (oral part of the pharynx) reaches from the Uvula to the level of the hyoid bone. It opens anteriorly, through the isthmus faucium, into the mouth, while in its lateral wall, between the two palatine arches, is the palatine tonsil. [WP,unvetted]." [Wikipedia:Oropharynx] subset: uberon_slim synonym: "oral part of pharynx" EXACT [] synonym: "mesopharynx" RELATED [Wikipedia:Pharynx] xref: FMA:54879 ! Oropharynx xref: GAID:340 ! oropharynx xref: VHOG:0000457 ! oropharynx xref: MA:0000351 ! oropharynx xref: MAT:0000446 ! oropharynx xref: ncithesaurus:Oropharynx ! Oropharynx xref: EFO:0001976 ! oropharynx xref: OpenCyc:Mx4rwACoxpwpEbGdrcN5Y29ycA ! oropharynx xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Illu_pharynx.jpg/200px-Illu_pharynx.jpg xref: EMAPA:25094 ! oropharynx xref: MESH:A03.867.603 ! oropharynx xref: EV:0100067 ! oropharynx xref: VSAO:0000034 ! oropharynx xref: EHDAA2:0004082 ! oropharynx is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0005409 ! gastrointestinal system relationship: develops_from UBERON:0010023 {source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 2 xref: SCTID:263376008 ! Entire oropharynx xref: XAO:0004048 ! oropharynx synonym: "pars oralis pharyngis" RELATED LATIN [Wikipedia:Oropharynx] xref: http://upload.wikimedia.org/wikipedia/commons/4/4a/Illu_pharynx.jpg property_value: external_definition "One of the three anatomic divisions of the pharynx that lies posterior to the mouth and is continuous above with the nasopharynx and below with the laryngopharynx. It extends behind the mouth from the soft palate above to the level of the hyoid bone below and contains the palatine and lingual tonsils. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000457", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/oropharynx", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "oropharyngeal" xsd:string xref: UMLS:C0521367 [Term] id: UBERON:0009959 name: lumen of oropharynx synonym: "oropharynx lumen" EXACT [FMA:55095] synonym: "oropharyngeal cavity" EXACT [EHDAA2:0004556] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001729 ! oropharynx relationship: part_of UBERON:0001729 ! oropharynx relationship: develops_from UBERON:0006272 {source="EHDAA2"} ! oronasal cavity relationship: part_of UBERON:0001731 ! cavity of pharynx xref: FMA:55095 ! lumen of oropharynx xref: EHDAA2:0004556 ! oropharyngeal cavity [Term] id: UBERON:0001051 name: hypopharynx def: "Bottom part of the pharynx, and is the part of the throat that connects to the esophagus." [Wikipedia:Hypopharynx] subset: uberon_slim synonym: "laryngeal pharynx" EXACT [FMA:54877] synonym: "laryngopharynx" EXACT [FMA:54877] synonym: "pars laryngea pharyngis" RELATED [BTO:0001740] xref: FMA:54880 ! Laryngopharynx xref: GAID:338 ! hypopharynx xref: VHOG:0000445 ! hypopharynx xref: MA:0001796 ! hypopharynx xref: ncithesaurus:Hypopharynx xref: BTO:0001740 ! hypopharynx xref: EFO:0001388 ! laryngopharynx xref: OpenCyc:Mx4rvq5O0JwpEbGdrcN5Y29ycA ! laryngopharynx xref: MESH:A03.867.490 ! hypopharynx xref: EV:0100068 ! hypopharynx is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001042 ! chordate pharynx relationship: continuous_with UBERON:0013472 ! upper esophagus xref: EHDAA2:0004574 ! laryngopharynx xref: SCTID:281490009 ! Entire hypopharynx synonym: "pars laryngea pharyngis" RELATED LATIN [Wikipedia:Hypopharynx] xref: http://upload.wikimedia.org/wikipedia/commons/4/4a/Illu_pharynx.jpg property_value: external_definition "The inferior portion of the pharynx, between the epiglottis and the larynx. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000445", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/hypopharynx", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "hypopharyngeal" xsd:string xref: UMLS:C0020629 [Term] id: UBERON:0010384 name: lumen of laryngopharynx synonym: "laryngopharynx lumen" EXACT [FMA:55096] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001051 ! hypopharynx relationship: part_of UBERON:0001051 ! hypopharynx relationship: part_of UBERON:0001051 {source="FMA"} ! hypopharynx relationship: part_of UBERON:0001731 ! cavity of pharynx xref: FMA:55096 ! Lumen of laryngopharynx [Term] id: UBERON:0000006 name: islet of Langerhans def: "Regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells." [Wikipedia:Islets_of_Langerhans] comment: A primitive exocrine pancreas can be found in holocephalan cartilaginous fish; a pancreatic duct directly ending in the gut lumen is connected to a glandular structure made of exocrine cells and associated with cell islets, which comprises three different hormone-producing cell types: insulin, somatostatin and glucagon (Yui and Fujita, 1986)[PMID:16417468] subset: uberon_slim synonym: "islets of langerhans" RELATED [] synonym: "pancreatic insula" EXACT [] synonym: "pancreatic islet" EXACT [] synonym: "island of Langerhans" RELATED [BTO:0000991] synonym: "island of pancreas" RELATED [BTO:0000991] xref: BTO:0000991 xref: EFO:0000856 ! islet of Langerhans xref: FMA:16016 ! Pancreatic islet xref: GAID:324 ! islets of langerhan xref: VHOG:0000646 ! islet of Langerhans xref: MA:0000127 ! pancreatic islet xref: MAT:0000076 ! islet of Langerhans xref: MIAA:0000076 ! islet of Langerhans xref: XAO:0000159 ! Islets of Langerhans xref: ncithesaurus:Islet_of_Langerhans ! Islet of Langerhans xref: EMAPA:19246 ! islets of Langerhans of parenchyma of body of pancreas of gland of gut xref: EMAPA:19247 ! islets of Langerhans of parenchyma of head of pancreas of gland of gut xref: EMAPA:19248 ! islets of Langerhans of parenchyma of tail of pancreas of gland of gut xref: EV:0100130 ! islets of Langerhans xref: MESH:A03.734.414 ! islets of langerhan is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000016 ! endocrine pancreas relationship: has_part CL:0002067 {source="PMID:16417468"} ! type A enterocrine cell relationship: has_part CL:0000168 {source="PMID:16417468"} ! insulin secreting cell relationship: has_part CL:0000172 {source="PMID:16417468"} ! somatostatin secreting cell relationship: has_part CL:0000696 {gci_relation="part_of", gci_filler="NCBITaxon:117570", source="PMID:16417468"} ! PP cell relationship: has_part CL:0000696 {gci_relation="part_of", gci_filler="NCBITaxon:7778", source="PMID:16417468"} ! PP cell xref: AAO:0010406 ! islet of Langerhans xref: http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png property_value: external_definition "Anatomical structure which consists of glands developed from pancreatic ducts in the larvae and secrete insulin.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010406", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "Mammals, birds, reptiles and amphibians have a pancreas with similar histology and mode of development, while in some fish, the islet cells are segregated as Brockmann bodies.[well established][VHOG]" xsd:string {external_class="VHOG:0000646", ontology="VHOG", source="PMID:7600975 Slack JMW\, Developmental biology of the pancreas. Development (1995)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0022131 [Term] id: UBERON:0000007 name: pituitary gland def: "The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." [Wikipedia:Pituitary_gland, ZFIN:curator] comment: Taxon notes: The lamprey possesses a distinct pituitary organ and hormones, the ascidian does not show distinct evidence of them [Sower S, Freamat M, Kavanaugh S. The origins of the vertebrate hypothalamic–pituitary–gonadal (HPG) and hypothalamic–pituitary–thyroid (HPT) endocrine systems: new insights from lampreys. Gen Comp Endocrinol 2009;161:20-9] subset: uberon_slim subset: vertebrate_core synonym: "hypophysis" RELATED [ZFA:0000118] synonym: "hypophysis cerebri" RELATED [MA:0000176] synonym: "pituitary" EXACT [BTO:0001073] synonym: "pituitary body" EXACT [BTO:0001073] synonym: "glandula pituitaria" RELATED [BTO:0001073] xref: EFO:0000857 ! pituitary xref: EHDAA:2183 ! pituitary xref: EHDAA:4477 ! pituitary xref: FMA:13889 ! Pituitary gland xref: GAID:457 ! pituitary gland xref: MA:0000176 ! pituitary gland xref: MAT:0000077 ! pituitary xref: MIAA:0000077 ! pituitary xref: ncithesaurus:Pituitary_Gland xref: OpenCyc:Mx4rv6NQYJwpEbGdrcN5Y29ycA xref: TAO:0000118 ! hypophysis xref: XAO:0000017 ! hypophysis xref: ZFA:0000118 ! hypophysis xref: BTO:0001073 ! hypophysis xref: OpenCyc:Mx4rv6NQYJwpEbGdrcN5Y29ycA ! pituitary gland xref: NIF_GrossAnatomy:birnlex_1353 ! Hypophysis xref: VHOG:0000143 ! hypophysis xref: EHDAA2:0001471 ! pituitary xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Gray1180.png/200px-Gray1180.png xref: EMAPA:16647 ! pituitary of gland of diencephalon of future forebrain xref: EMAPA:16898 ! pituitary of gland of diencephalon of forebrain xref: MESH:A06.407.747 ! pituitary gland xref: EV:0100132 ! pituitary gland xref: BM:Die-Hy-HY ! hypophysis is_a: UBERON:0002368 {source="BTO"} ! endocrine gland relationship: part_of UBERON:0001894 {source="ZFA"} ! diencephalon relationship: develops_from UBERON:0000924 {source="Wikipedia"} ! ectoderm relationship: has_part UBERON:0002196 ! adenohypophysis relationship: has_part UBERON:0002198 ! neurohypophysis relationship: has_part CL:0000440 {source="ZFA"} ! melanocyte stimulating hormone secreting cell relationship: has_part CL:0000642 {source="ZFA"} ! folliculostellate cell relationship: only_in_taxon NCBITaxon:7742 {source="PMID:19084529"} ! Vertebrata relationship: has_function_in GO:0007276 ! gamete generation xref: AAO:0010536 ! pituitary gland xref: SCTID:181125003 ! Entire pituitary gland subset: organ_slim synonym: "hypophysis, glandula pituitaria" RELATED LATIN [Wikipedia:Pituitary_gland] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Gray1180.png property_value: external_definition "An endocrine gland derived from infundibulum of the floor of the diencephalon and an ectodermal dorsal protrusion from the buccal cavity which controls the secretion of many hormones influencing the function of various organs of the body.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010536", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000118", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0000143", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0032005 [Term] id: UBERON:0011216 name: organ system subdivision def: "Anatomical structure, which consists of a specific set of the members of (predominantly) one organ or organ part subclass interconnected by zones of continuity or body substances; is demarcated from other subdivisions of the same organ system by one or more zones of continuity or anatomical lines; together with other subdivisions of the same organ system, it constitutes an organ system. Examples: rib cage, facial skeleton, portal system, central nervous system, upper respiratory tract, muscle group of back." [FMA:67509] subset: upper_level is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0000467 ! anatomical system xref: FMA:67509 ! organ system subdivision xref: FBbt:00007330 ! organ system subdivision xref: SCTID:91690000 ! Entire subdivision of organ system [Term] id: UBERON:0000010 name: peripheral nervous system def: "Nervous structures including ganglia outside of the central nervous system. Divided into somatic nervous system and autonomic nervous system" [FB:gg, OMD:peripheral+nervous+system, Wikipedia:Peripheral_nervous_system, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "PNS" RELATED [] xref: AAO:0000429 ! peripheral_nervous_system xref: BILA:0000081 xref: BTO:0001028 xref: EFO:0000891 ! peripheral nervous system xref: EHDAA:2893 ! peripheral nervous system xref: FBbt:00005098 ! peripheral nervous system xref: FMA:9903 ! Peripheral nervous system xref: GAID:715 ! peripheral nervous system xref: VHOG:0000399 ! peripheral nervous system xref: MA:0000218 ! peripheral nervous system xref: MAT:0000338 ! peripheral nervous system xref: MIAA:0000338 ! peripheral nervous system xref: NIF_GrossAnatomy:birnlex_1111 ! Peripheral nervous system xref: TAO:0000142 ! peripheral nervous system xref: XAO:0000178 ! peripheral nervous system xref: ZFA:0000142 ! peripheral nervous system xref: ncithesaurus:Peripheral_Nervous_System ! Peripheral Nervous System xref: EHDAA2:0001445 ! peripheral nervous system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Nervous_system_diagram.png/200px-Nervous_system_diagram.png xref: EMAPA:16665 ! peripheral nervous system of nervous system of organ system xref: EMAPA:18370 ! peripheral nervous system of nervous system of tail of embryo xref: MESH:A08.800 ! peripheral nervous system xref: EV:0100335 ! peripheral nervous system is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0001016 ! nervous system relationship: spatially_disjoint_from UBERON:0001017 ! central nervous system xref: SCTID:362292005 ! Entire peripheral nervous system synonym: "pars peripherica; systema nervosum periphericum" RELATED LATIN [Wikipedia:Peripheral_nervous_system] xref: http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png property_value: external_definition "Part of nervous system in which nerves extend throughout the body outside of the brain and spinal cord.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000429", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Nervous structures including ganglia outside of the central nervous system. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000142", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) specific vertebrate traits within the chordate phylum such as skeletal tissues, PNS, and spectacular head and brain development, are linked to the NC (neural crest) and its derivatives.[well established][VHOG]" xsd:string {external_class="VHOG:0000399", ontology="VHOG", source="DOI:10.1007/978-0-387-46954-6_6 Dupin E\, Creuzet S\, Le Douarin NM\, The contribution of the neural crest to the vertebrate body. Advances in experimental medicine and biology (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0206417 [Term] id: UBERON:0000011 name: parasympathetic nervous system def: "The parasympathetic nervous system (PSNS) is a division of the autonomic nervous system (ANS), along with the sympathetic nervous system (SNS) and enteric nervous system (ENS). The ANS is a subdivision of the peripheral nervous system (PNS). ANS sends fibers to three tissues: cardiac muscle, smooth muscle, or glandular tissue. This stimulation, sympathetic or parasympathetic, is to control smooth muscle contraction, regulate cardiac muscle, or stimulate or inhibit glandular secretion [Wikipedia]. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia [GO]." [Wikipedia:Parasympathetic_nervous_system] comment: Development notes: has developmental contribution from NC in verteberates (UBERONREF:0000002) subset: uberon_slim subset: vertebrate_core synonym: "parasympathetic part of autonomic division of nervous system" EXACT [] synonym: "PNS - parasympathetic" EXACT [] xref: EFO:0000894 ! parasympathetic nervous system xref: EHDA:10096 ! parasympathetic xref: FMA:9907 ! Parasympathetic nervous system xref: GAID:708 ! parasympathetic nervous system xref: VHOG:0000755 ! parasympathetic nervous system xref: MA:0000223 ! parasympathetic nervous system xref: MAT:0000101 ! PNS - parasympathetic xref: MIAA:0000101 ! PNS - parasympathetic xref: NIF_GrossAnatomy:birnlex_2517 ! Parasympathetic nervous system xref: TAO:0001575 ! parasympathetic nervous system xref: ZFA:0001575 ! parasympathetic nervous system xref: ncithesaurus:Parasympathetic_Nervous_System ! Parasympathetic Nervous System xref: BTO:0001833 ! parasympathetic nervous system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f7/Gray839.png/200px-Gray839.png xref: EHDAA2:0001402 ! parasympathetic peripheral nervous system xref: EMAPA:17270 ! parasympathetic xref: MESH:A08.800.050.600 ! parasympathetic nervous system xref: EHDAA:4655 ! parasympathetic is_a: UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0002410 ! autonomic nervous system synonym: "pars parasympathica divisionis autonomici systematis nervosi" EXACT LATIN [FMA:TA, FMA:9907] xref: AAO:0010488 ! parasympathetic nervous system xref: SCTID:362496006 ! Entire parasympathetic nervous system synonym: "pars parasympathica divisionis autonomici systematis nervosi" RELATED LATIN [Wikipedia:Parasympathetic_nervous_system] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png property_value: external_definition "Part of the autonomic nervous system which has opposing physiological effects of the sympathetic nervous system. Examples include decreasing the heart rate or dilating the blood vessels.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010488", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "In mammals, the autonomic nervous system is divided into two contrasting, antagonistic systems of control over visceral activity: the sympathetic system and the parasympathetic system (reference 1); In general, the teleosts may be considered phylogenetically the first class of vertebrates in which the heart is regulated by both sympathetic and parasympathetic neural pathways (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000755", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.634\, DOI:10.1016/S0306-4530(98)00057-2 Porges SW\, Love: an emergent property of the mammalian autonomic nervous system. Psychoneuroendocrinology (1998)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0030510 [Term] id: UBERON:0000012 name: somatic nervous system def: "The part of the peripheral nervous system consisting of efferent nerves responsible for stimulating muscle contraction, including all the neurons connected with skeletal muscles, skin, and sense organs[WP, modified]." [Wikipedia:Somatic_nervous_system] subset: uberon_slim synonym: "PNS - somatic" EXACT [] synonym: "somatic peripheral nervous system" EXACT [NIF_GrossAnatomy:nlx_anat_100301] synonym: "somatic nervous system, somatic division" EXACT [NIF_GrossAnatomy:nlx_anat_100301] xref: EFO:0000892 ! somatic nervous system xref: EFO:0000898 ! somatic nervous system xref: FMA:9904 ! Somatic nervous system xref: MA:0002850 ! somatic nervous system xref: MAT:0000099 ! PNS - somatic xref: MAT:0000342 ! somatic nervous system xref: MIAA:0000099 ! PNS - somatic xref: MIAA:0000342 ! somatic nervous system xref: WBbt:0005760 ! somatic nervous system xref: NIF_GrossAnatomy:nlx_anat_100301 ! Somatic peripheral nervous system is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0000010 ! peripheral nervous system [Term] id: UBERON:0000013 name: sympathetic nervous system def: "The Sympathetic Nervous System (SNS) is a branch of the autonomic nervous system along with the enteric nervous system and parasympathetic nervous system. It is always active at a basal level (called sympathetic tone) and becomes more active during times of stress. Its actions during the stress response comprise the fight-or-flight response [Wikipedia]. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." [Wikipedia:Sympathetic_nervous_system] comment: Development notes: has developmental contribution from NC in verteberates (UBERONREF:0000002) subset: uberon_slim subset: vertebrate_core synonym: "sympathetic nervous system" EXACT [] synonym: "sympathetic part of autonomic division of nervous system" EXACT [] xref: EFO:0000893 ! sympathetic nervous system xref: FMA:9906 ! Sympathetic nervous system xref: GAID:710 ! sympathetic nervous system xref: VHOG:0000384 ! sympathetic nervous system xref: MA:0000225 ! sympathetic nervous system xref: MIAA:0000100 ! PNS - sympathetic xref: NIF_GrossAnatomy:birnlex_2516 ! Sympathetic nervous system xref: TAO:0001576 ! sympathetic nervous system xref: ZFA:0001576 ! sympathetic nervous system xref: ncithesaurus:Sympathetic_Nervous_System ! Sympathetic Nervous System xref: BTO:0001832 ! sympathetic nervous system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Gray838.png/200px-Gray838.png xref: EHDAA2:0001971 ! sympathetic peripheral nervous system xref: EMAPA:16985 ! sympathetic xref: MESH:A08.800.050.800 ! sympathetic nervous system xref: EHDAA:3769 ! sympathetic is_a: UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0002410 ! autonomic nervous system synonym: "pars sympathica divisionis autonomici systematis nervosi" EXACT LATIN [FMA:TA, FMA:9906] xref: AAO:0010487 ! sympathetic nervous system xref: SCTID:362484004 ! Entire sympathetic nervous system synonym: "pars sympathica divisionis autonomici systematis nervosi" RELATED LATIN [Wikipedia:Sympathetic_nervous_system] xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png property_value: external_definition "Part of the autonomic nervous system which has opposing physiological effects of the parasympathetic nervous system. Examples include increasing the heart rate or constricting the blood vessels.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010487", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The part of the autonomic nervous system which chiefly contains adrenergic fibres and tends to control and reduce secretions, decrease the contractility and hence the tone of smooth muscles and provoke the contraction of blood vessels. Essentially, it consists of preganglionic fibres from the thoracic and upper lumbar parts of the spinal cord. These fibres, by means of delicate rami communicantes, cross over to ganglia sited in a pair of ganglionated cords on each side of the vertebral column or to more peripheral ganglia. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000384", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The autonomic nervous system is composed of three divisions: the sympathetic division, the parasympathetic division, and the enteric division. (...) In ray-finned teleost fishes, a sympathetic chain is present, and dual innervation of additional organs can be observed. A similar pattern can be found in amphibians (...). The evolution of the autonomic nervous system has been quite conservative, especially in the tetrapod lineage.[well established][VHOG]" xsd:string {external_class="VHOG:0000384", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.461-463", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0039044 [Term] id: UBERON:0000015 name: anatomical boundary def: "Structural anatomical relation which holds between each anatomical entity of one to three dimensions and some immaterial anatomical entity of one lower dimension such that the latter demarcates (delimits) the former from its neighborhood." [FMA:256502] synonym: "anatomical boundary entity" EXACT [FMA:50705] subset: upper_level xref: FMA:50705 ! Anatomical boundary entity xref: AEO:0000192 ! anatomical boundary is_a: UBERON:0000466 ! immaterial anatomical entity [Term] id: UBERON:0007651 ! anatomical junction name: anatomical junction def: "Anatomical structure in which parts of two or more anatomical structures establish physical continuity with one another or intermingle their component parts. Examples: gastroesophageal junction, line alba, knee joint.[FMA]" [FMA:5898] subset: upper_level xref: FMA:5898 ! anatomical junction xref: SCTID:91833003 ! Anatomical junction is_a: UBERON:0000477 ! anatomical cluster [Term] id: UBERON:0006800 name: anatomical line def: "Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface." [CARO:MAH] subset: upper_level xref: HAO:0000008 ! anatomical line xref: ZFA:0001689 ! anatomical line xref: EHDAA2:0003008 ! anatomical line xref: AEO:0000008 ! anatomical line xref: BILA:0000008 ! anatomical line xref: CARO:0000008 ! anatomical line xref: TGMA:0001828 ! anatomical line xref: FMA:9657 ! Anatomical line is_a: UBERON:0000015 ! anatomical boundary disjoint_from: UBERON:0000464 ! anatomical space xref: AAO:0010267 ! anatomical line xref: XAO:0004003 ! anatomical line xref: TAO:0001837 ! anatomical line property_value: external_definition "Non-material anatomical entity of one dimension, whiVSAO forms a boundary of an anatomical surface or is a modulation of an anatomical surface.[CARO]" xsd:string {ontology="CARO", external_class="CARO:0000008", date_retrieved="2012-08-14", source="CARO:MAH", source="FMA:9657"} [Term] id: UBERON:0000016 name: endocrine pancreas def: "The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin[GO]." [GOC:GO, Wikipedia:Islets_of_Langerhans] comment: Editor notes - endocrine and exocrine pancrease are not co-associated in hagfishes or lampreys [PMID:20959416] - create a separate class for these? subset: uberon_slim subset: vertebrate_core synonym: "islets of Langerhans part of pancreas" RELATED [] synonym: "endocrine pancreas" EXACT [] synonym: "pars endocrina pancreatis" EXACT [] synonym: "endocrine part of pancreas" RELATED [BTO:0000650] xref: BTO:0000650 xref: FMA:16018 ! Endocrine pancreas xref: VHOG:0000049 ! endocrine pancreas xref: MA:0001582 ! endocrine pancreas xref: TAO:0001260 ! endocrine pancreas xref: ZFA:0001260 ! endocrine pancreas xref: ncithesaurus:Endocrine_Pancreas ! Endocrine Pancreas xref: EV:0100129 ! endocrine pancreas is_a: UBERON:0002075 ! viscus relationship: part_of UBERON:0001264 ! pancreas relationship: develops_from UBERON:0003923 ! dorsal pancreatic bud relationship: capable_of GO:0030073 {source="GO"} ! insulin secretion relationship: capable_of GO:0070091 {source="GO"} ! glucagon secretion relationship: capable_of GO:0070253 {source="GO"} ! somatostatin secretion xref: SCTID:361339003 ! Entire endocrine pancreas subset: organ_slim property_value: external_definition "The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001260", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000049", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/Pancreas", source="http://bgee.unil.ch/"} property_value: homology_notes "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {external_class="VHOG:0000049", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD\, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000017 name: exocrine pancreas def: "The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. The exocrine pancreas is composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion." [GOC:GO, Wikipedia:Exocrine_component_of_pancreas] subset: uberon_slim subset: vertebrate_core synonym: "exocrine pancreas" EXACT [] synonym: "pars exocrina pancreatis" EXACT [] synonym: "exocrine part of pancreas" RELATED [BTO:0000434] xref: BTO:0000434 xref: FMA:16017 ! Exocrine pancreas xref: VHOG:0000048 ! exocrine pancreas xref: MA:0002415 ! exocrine pancreas xref: TAO:0001249 ! exocrine pancreas xref: XAO:0000137 ! exocrine pancreas xref: ZFA:0001249 ! exocrine pancreas xref: ncithesaurus:Exocrine_Pancreas ! Exocrine Pancreas xref: EV:0100093 ! exocrine pancreas is_a: UBERON:0002075 ! viscus relationship: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0002330 ! exocrine system relationship: develops_from UBERON:0003924 ! ventral pancreatic bud relationship: has_function_in GO:0007586 ! digestion xref: AAO:0010407 ! exocrine pancreas xref: SCTID:248202004 ! Entire exocrine pancreas subset: organ_slim property_value: external_definition "The exocrine pancreas is composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001249", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "The part of the pancreas that acts as an exocrine gland, consisting of the pancreatic acini, which produce pancreatic juice and secrete it into the intestine to aid in protein digestion. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000048", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/Pancreas", source="http://bgee.unil.ch/"} property_value: homology_notes "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {external_class="VHOG:0000048", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD\, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0553695 [Term] id: UBERON:0003921 name: pancreas primordium def: "embryonic structure that develops into pancreatic bud." [http://en.wikipedia.org/wiki/Pancreas#Embryological_development] comment: AO notes: in EHDAA2 this has dorsal and ventral primordia as parts. the buds are part of the primordium, with the ducts developing from the buds; only parenchyma and ducts have contribution from buds. Terminology notes: revisit after standardizing terms 'primordium', 'anlagen', 'bud' subset: vertebrate_core synonym: "pancreatic anlage" RELATED [] synonym: "pancreatic primordium" EXACT [] synonym: "primordial pancreas" RELATED [FMA:79792] synonym: "pancreatic endoderm" RELATED [EFO:0002579] xref: ZFA:0000254 ! pancreas primordium xref: EHDAA:2163 ! pancreas primordium xref: EHDAA2:0001382 ! pancreas primordium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Gray982.png/200px-Gray982.png xref: EMAPA:17066 ! pancreas primordium xref: XAO:0001101 ! first pancreatic bud xref: EFO:0003434 ! pancreas primordium xref: FMA:79792 ! primordial pancreas is_a: UBERON:0001048 {source="EHDAA2"} ! primordium relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0000925 {source="Wikipedia"} ! endoderm relationship: part_of UBERON:0007026 ! primitive gut xref: TAO:0000254 ! pancreas primordium xref: EFO:0002579 ! pancreatic endoderm [Term] id: UBERON:0009752 name: pancreas mesenchyme def: "the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas" [MP:0011265] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001264 ! pancreas xref: EFO:0002557 ! pancreatic mesenchyme [Term] id: UBERON:0010375 name: pancreas dorsal primordium comment: Consider merging with dorsal pancreatic bud. Starts at CS12 in human (EHDAA2, embryology.ch 'bud anlagen') is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland is_a: UBERON:0001048 {source="EHDAA2"} ! primordium synonym: "dorsal pancreas" RELATED INCONSISTENT [FMA:79793] relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium xref: EHDAA2:0001384 ! pancreas dorsal primordium xref: FMA:79793 ! dorsal pancreas [Term] id: UBERON:0010376 name: pancreas ventral primordium comment: Starts at CS14 in human (EHDAA2) or CS13-14 (embryology.ch 'bud anlagen') synonym: "ventral pancreas" RELATED INCONSISTENT [FMA:79794] is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland is_a: UBERON:0001048 {source="EHDAA2"} ! primordium relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium xref: EHDAA2:0001387 ! pancreas ventral primordium xref: FMA:79794 ! ventral pancreas [Term] id: UBERON:0003922 ! pancreatic bud name: pancreatic bud def: "The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. In humans, an embryonic structure that is an outgrowth of the duodenum during embryogenesis - joins together to form the adult pancreas[WP]." [Wikipedia:Pancreatic_bud, PMID:16417468] synonym: "pancreatic anlage" RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/49/Suckale08FBS_fig1_pancreas_development.jpeg/300px-Suckale08FBS_fig1_pancreas_development.jpeg xref: ZFA:0001390 ! pancreatic bud xref: ncithesaurus:Pancreatic_Bud ! Pancreatic Bud xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Gray982.png/200px-Gray982.png xref: EFO:0003470 ! pancreatic bud xref: SCTID:360398004 ! Pancreatic bud is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium relationship: develops_from UBERON:0009497 {source="EHDAA2-inferred"} ! epithelium of foregut-midgut junction relationship: develops_from UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0001041 {source="Wikipedia:Pancreas#Embryological_development"} ! foregut relationship: develops_from UBERON:0002114 {exception="zebrafish", source="Wikipedia:Pancreatic_bud"} ! duodenum xref: TAO:0001390 ! pancreatic bud xref: http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png synonym: "pancreatic buds" EXACT PLURAL [TAO:0001390] xref: UMLS:C1283285 [Term] id: UBERON:0003923 ! dorsal pancreatic bud name: dorsal pancreatic bud def: "pancreatic bud that gives rise to the accessory pancreatic duct." [Wikipedia:Pancreatic_bud] subset: vertebrate_core synonym: "dorsal pancreas anlage" RELATED [] synonym: "dorsal pancreatic anlage" RELATED [] synonym: "posterior pancreatic anlage" RELATED [] synonym: "posterior pancreatic bud" RELATED [] synonym: "pancreas primordium dorsal bud" EXACT [] synonym: "pancreas dorsal primordium duct bud" EXACT [EHDAA2:0001385] xref: ZFA:0001370 ! posterior pancreatic bud xref: XAO:0000467 ! dorsal pancreatic bud xref: VHOG:0001428 ! dorsal pancreatic bud xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Gray982.png/200px-Gray982.png xref: EFO:0003465 ! posterior pancreatic bud is_a: UBERON:0003922 ! pancreatic bud relationship: develops_from UBERON:0001045 {source="XAO"} ! midgut relationship: induced_by UBERON:0002328 {gci_relation="part_of", gci_filler="NCBITaxon:10088", source="PMID:16417468"} ! notochord relationship: induced_by UBERON:0005805 {gci_relation="part_of", gci_filler="NCBITaxon:10088", source="PMID:16417468"} ! dorsal aorta relationship: part_of UBERON:0010375 {source="EHDAA2"} ! pancreas dorsal primordium xref: AAO:0011031 ! dorsal pancreatic bud xref: SCTID:361435005 ! Dorsal pancreatic bud xref: EHDAA2:0001385 ! pancreas dorsal primordium duct bud xref: EMAPA:17067 ! dorsal bud xref: TAO:0001370 ! posterior pancreatic bud property_value: external_definition "The pancreatic bud that gives rise to the accessory pancreatic duct.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011031", date_retrieved="2012-06-20", source="XAO:curator"} property_value: homology_notes "In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001428", ontology="VHOG", source="DOI:10.1016/S0012-1606(03)00308-7 Field HA\, Dong PD\, Beis D\, Stainier DY\, Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology (2003)\, DOI:10.2337/diabetes.49.2.225 Polak M\, Bouchareb-Banaei L\, Scharfmann R\, Czernichow P\, Early pattern of differentiation in the human pancreas. Diabetes (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003924 name: ventral pancreatic bud def: "pancreatic bud that gives rise to the major pancreatic duct." [Wikipedia:Pancreatic_bud] comment: Development notes: the ventral pancreas and liver are derived from a common precursor cell population[PMID:16417468]. TODO - add this relationship. // The ventral pancreatic bud becomes the head and uncinate process, and comes from the hepatic diverticulum[WP] subset: vertebrate_core synonym: "ventral pancreas anlage" RELATED [] synonym: "ventral pancreatic anlage" RELATED [] synonym: "anterior pancreatic anlage" RELATED [] synonym: "anterior pancreatic bud" RELATED [] synonym: "pancreas primordium ventral bud" EXACT [] synonym: "pancreas ventral primordium duct bud" EXACT [EHDAA2:0001389] xref: ZFA:0001369 ! anterior pancreatic bud xref: XAO:0001103 ! ventral pancreatic bud xref: VHOG:0001429 ! ventral pancreatic bud xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Gray982.png/200px-Gray982.png xref: EFO:0003464 ! anterior pancreatic bud xref: AAO:0011111 ! ventral pancreatic bud xref: SCTID:361437002 ! Ventral pancreatic bud is_a: UBERON:0003922 ! pancreatic bud relationship: part_of UBERON:0010376 {source="EHDAA2"} ! pancreas ventral primordium relationship: develops_from UBERON:0008835 {source="WP", source="PMID:16417468"} ! hepatic diverticulum xref: EHDAA2:0001389 ! pancreas ventral primordium duct bud xref: EMAPA:17256 ! ventral bud xref: TAO:0001369 ! anterior pancreatic bud property_value: homology_notes "In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001429", ontology="VHOG", source="DOI:10.1016/S0012-1606(03)00308-7 Field HA\, Dong PD\, Beis D\, Stainier DY\, Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology (2003)\, DOI:10.2337/diabetes.49.2.225 Polak M\, Bouchareb-Banaei L\, Scharfmann R\, Czernichow P\, Early pattern of differentiation in the human pancreas. Diabetes (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009708 name: dorsal pancreas is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland synonym: "pancreatis dorsalis" RELATED [] relationship: develops_from UBERON:0010375 {source="EHDAA2"} ! pancreas dorsal primordium relationship: has_developmental_contribution_from UBERON:0003923 {source="cjm"} ! dorsal pancreatic bud relationship: part_of UBERON:0001264 {source="EHDAA2"} ! pancreas xref: EHDAA2:0001371 ! dorsal pancreas subset: organ_slim [Term] id: UBERON:0009709 name: ventral pancreas is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland synonym: "pancreatis ventralis" RELATED [] relationship: develops_from UBERON:0010376 {source="EHDAA2"} ! pancreas ventral primordium relationship: has_developmental_contribution_from UBERON:0003924 {source="cjm"} ! ventral pancreatic bud relationship: part_of UBERON:0001264 {source="EHDAA2"} ! pancreas xref: EHDAA2:0001393 ! ventral pancreas subset: organ_slim [Term] id: UBERON:0001263 name: pancreatic acinus def: "the secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct." [MP:0009145] comment: This class was created automatically from a combination of ontologies synonym: "acinus pancreaticus" EXACT LATIN [FMA:16011] synonym: "pancreas acinus" EXACT [] synonym: "pancreatic acini" RELATED PLURAL [] synonym: "pancreatic acinar" RELATED [TEMP:MP] xref: FMA:16011 ! Pancreatic acinus xref: MA:0002417 ! pancreatic acinus xref: ncithesaurus:Pancreatic_Acinus ! Pancreatic Acinus intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0007324 {source="FMA"} ! pancreatic lobe xref: SCTID:247604006 ! Entire pancreatic acinus xref: UMLS:C0227578 [Term] id: UBERON:0001264 name: pancreas def: "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]. The mature pancreas of higher vertebrates and mammals comprises two major functional units: the exocrine pancreas, which is responsible for the production of digestive enzymes to be secreted into the gut lumen, and the endocrine pancreas, which has its role in the synthesis of several hormones with key regulatory functions in food uptake and metabolism. The exocrine portion constitutes the majority of the mass of the pancreas, and contains only two different cell types, the secretory acinar cells and the ductular cells. The endocrine portion, which comprises only 1–2% of the total mass, contains five different cell types, which are organized into mixed functional assemblies referred to as the islets of Langerhans[PMID]." [Wikipedia:Pancreas, PMID:16417468, GO:0031016] comment: taxon notes: As a secretory organ serving exocrine and endocrine functions, the pancreas is specific to the vertebrates[PMID:16417468] Hagfishes and lampreys are unique in the complete separation of their endocrine pancreas (islet or- gan) and their exocrine pancreas (50). The endocrine and exocrine pancreas are coassociated in crown gnathostomes (50). In Branchiostoma and Ciona, there is no diverticulum as there is in hagfishes, lampreys, and gnathostomes, only dispersed insulin-secreting cells in the walls of the gastrointestinal tract (51, 52) [PMID:20959416]. The zebrafish does not have a discrete pancreas. Exocrine pancreatic tissue can be found scattered along the intestinal tract (Figures 16 and 17 ). The acinar structure of the exocrine pancreas is very similar to that of mammals and comprises cells with a very dark, basophilic cytoplasm subset: uberon_slim subset: vertebrate_core subset: major_organ xref: BTO:0000988 xref: EFO:0000855 ! pancreas xref: EHDAA:6893 ! pancreas xref: FMA:7198 ! Pancreas xref: GAID:334 ! pancreas xref: VHOG:0000050 ! pancreas xref: MA:0000120 ! pancreas xref: MAT:0000075 ! pancreas xref: MIAA:0000075 ! pancreas xref: ncithesaurus:Pancreas xref: OpenCyc:Mx4rvVimZZwpEbGdrcN5Y29ycA xref: TAO:0000140 ! pancreas xref: XAO:0000136 ! pancreas xref: ZFA:0000140 ! pancreas xref: galen:Pancreas ! pancreas xref: OpenCyc:Mx4rvVimZZwpEbGdrcN5Y29ycA ! pancreas xref: EHDAA2:0001367 ! pancreas xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3f/Illu_pancrease.svg/200px-Illu_pancrease.svg.png xref: EMAPA:17503 ! pancreas of gland of foregut-midgut junction xref: EMAPA:18816 ! pancreas of gland of gut xref: MESH:A03.734 ! pancrea xref: EV:0100092 ! pancreas is_a: UBERON:0002075 ! viscus relationship: has_developmental_contribution_from UBERON:0003922 ! pancreatic bud relationship: part_of UBERON:0000949 ! endocrine system relationship: has_developmental_contribution_from UBERON:0003923 {source="Wikipedia"} ! dorsal pancreatic bud relationship: has_developmental_contribution_from UBERON:0003924 {source="Wikipedia"} ! ventral pancreatic bud relationship: only_in_taxon NCBITaxon:7742 {source="PMID:16417468"} ! Vertebrata xref: AAO:0010112 ! pancreas xref: SCTID:181277001 ! Entire pancreas subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/3/3f/Illu_pancrease.svg property_value: external_definition "Organ which secretes a fluid containing enzymes that aid in the digestion of food.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010112", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {external_class="VHOG:0000050", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD\, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "pancreatic" xsd:string xref: UMLS:C0030274 [Term] id: UBERON:0007329 ! pancreatic duct name: pancreatic duct def: "A duct that is part of the pancreas and connected to the duodenum." [UBERON:cjm, Wikipedia:Pancreatic_duct] comment: note that this class groups together accessory (dorsal) and main (ventral) pancreatic ducts. AO notes: in EHDAA2, the dorsal and ventral ducts are classified as epithelial sacs - review after overhaul of duct/epithelia terms subset: vertebrate_core synonym: "pancreas duct" EXACT [OBOL:accepted] synonym: "duct of pancreas" EXACT [OBOL:accepted] xref: MA:0000124 ! pancreatic duct xref: FMA:10419 ! Pancreatic duct xref: EHDAA:9194 ! pancreatic duct xref: TAO:0001372 ! pancreatic duct xref: ZFA:0001372 ! pancreatic duct is_a: UBERON:0003928 {source="ZFA"} ! digestive system duct relationship: part_of UBERON:0000017 {source="MA"} ! exocrine pancreas relationship: continuous_with UBERON:0002114 ! duodenum relationship: develops_from UBERON:0003922 ! pancreatic bud xref: SCTID:181278006 ! Entire pancreatic duct synonym: "ductus pancreaticus" RELATED LATIN [Wikipedia:Pancreatic_duct] xref: http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png xref: VHOG:0000254 ! pancreatic duct property_value: external_definition "Duct connecting the pancreas with the intestine. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000254", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000254", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS\, Lorent K\, Pack M\, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009970 name: epithelium of pancreatic duct comment: Editor note: in EHDAA2, the embryonic pancreatic ducts (dorsal, ventral) are classified as eithelial sacs, which would render them subclasses this synonym: "pancreatic duct epithelium" EXACT [FMA:67681] synonym: "pancreatic ductal epithelium" EXACT [FMA:67681] xref: FMA:67681 ! epithelium of pancreatic duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0007329 ! pancreatic duct relationship: develops_from UBERON:0000924 {source="FMA-inferred"} ! ectoderm xref: EFO:0002556 ! pancreatic duct epithelium def: "An epithelium that is part of a pancreatic duct." [OBOL:automatic] [Term] id: UBERON:0001064 name: ventral pancreatic duct alt_id: UBERON:0005627 def: "a duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla." [Wikipedia:Pancreatic_duct] comment: Development notes: Upon reaching its final destination, the ventral pancreatic bud fuses with the much larger dorsal pancreatic bud. At this point of fusion, the main ducts of the ventral and dorsal pancreatic buds fuse, forming the duct of Wirsung, the main pancreatic duct.[WP] subset: uberon_slim synonym: "ductus pancreatis ventralis" RELATED [] synonym: "duct of Wirsung" EXACT [Wikipedia:Pancreatic_duct] synonym: "canal of Wirsung" RELATED [BTO:0002362] synonym: "hepaticopancreatic duct" RELATED [BTO:0002362] synonym: "main pancreatic duct" EXACT [MA:0000126] synonym: "chief pancreatic duct" EXACT [FMA:16003] synonym: "pancreatic duct" BROAD [MESH:A03.734.667] xref: FMA:16003 ! main pancreatic duct xref: EHDAA2:0001396 ! ventral pancreas duct xref: RETIRED_EHDAA2:0002177 ! ventral pancreatic duct xref: EHDAA:6905 ! ventral pancreatic duc xref: GAID:337 ! pancreatic duct xref: MA:0000126 ! ventral pancreatic duct xref: ncithesaurus:Pancreatic_Duct xref: BTO:0002362 ! pancreatic duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/15/Gray1100.png/200px-Gray1100.png xref: MESH:A03.734.667 ! pancreatic duct xref: VHOG:0000256 ! ventral pancreatic duct xref: EMAPA:18821 ! ventral pancreatic duct of head of pancreas of gland of gut is_a: UBERON:0007329 {source="FMA"} ! pancreatic duct relationship: develops_from UBERON:0003924 {source="EHDAA2"} ! ventral pancreatic bud relationship: part_of UBERON:0000017 ! exocrine pancreas relationship: continuous_with UBERON:0001174 ! common bile duct relationship: channel_for UBERON:0001970 ! bile relationship: channels_into UBERON:0004913 ! hepatopancreatic ampulla xref: SCTID:245385001 ! Entire duct of Wirsung property_value: homology_notes "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000256", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS\, Lorent K\, Pack M\, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0030288 [Term] id: UBERON:0005429 name: dorsal pancreatic duct alt_id: UBERON:0005603 def: "Most people have just one pancreatic duct. However, some have an additional accessory pancreatic duct also called the Duct of Santorini, which connects straight to the duodenum at the minor duodenal papilla. Both these ducts connect to the second part (the vertical one) of the duodenum. However, the Duct of Santorini, which bypasses the Ampulla of Vater, is non-functional whereas the Duct of Wirsung is functional and carries the digestive enzymes released by the pancreas. It is named for Giovanni Domenico Santorini." [Wikipedia:Accessory_pancreatic_duct] synonym: "ductus pancreatis dorsalis" RELATED [] synonym: "accessory pancreatic duct of santorini" RELATED [Wikipedia:Accessory_pancreatic_duct] synonym: "duct of Santorini" EXACT [Wikipedia:Accessory_pancreatic_duct, FMA:14534] synonym: "pancreatic duct of santorini" RELATED [Wikipedia:Accessory_pancreatic_duct] synonym: "Santorini's duct" EXACT [FMA:14534] synonym: "accessory pancreatic duct" EXACT [MA:0000125] xref: FMA:14534 ! Accessory pancreatic duct xref: EHDAA2:0001372 ! dorsal pancreas duct xref: EHDAA:9188 ! accessory pancreatic duct xref: MA:0000125 ! dorsal pancreatic duct xref: RETIRED_EHDAA2:0000417 ! dorsal pancreatic duct xref: EMAPA:17505 ! dorsal pancreatic duct of body of pancreas of gland of foregut-midgut junction xref: EMAPA:17512 ! dorsal pancreatic duct of tail of pancreas of gland of foregut-midgut junction xref: EMAPA:18818 ! dorsal pancreatic duct of body of pancreas of gland of gut xref: EMAPA:18825 ! dorsal pancreatic duct of tail of pancreas of gland of gut xref: EHDAA:3013 ! dorsal pancreatic duct xref: VHOG:0000255 ! dorsal pancreatic duct is_a: UBERON:0007329 {source="FMA"} ! pancreatic duct relationship: develops_from UBERON:0003923 {source="EHDAA2"} ! dorsal pancreatic bud xref: SCTID:245386000 ! Entire accessory pancreatic duct synonym: "ductus pancreaticus accessorius" RELATED LATIN [Wikipedia:Accessory_pancreatic_duct] xref: http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png property_value: homology_notes "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000255", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS\, Lorent K\, Pack M\, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001069 name: head of pancreas def: "The head of pancreas is a portion of the pancreas that is lodged within the curve of the duodenum, and is flattened anteriorly (from before). The other parts of the pancreas are the body and the tail. Its upper border is overlapped by the superior part of the duodenum and its lower overlaps the horizontal part; its right and left borders overlap in front, and insinuate themselves behind, the descending and ascending parts of the duodenum respectively. [WP,unvetted]." [Wikipedia:Head_of_pancreas] subset: uberon_slim synonym: "pancreas head" EXACT [] synonym: "pancreatic head" EXACT [] synonym: "right extremity of pancreas" EXACT [] xref: FMA:10468 ! Head of pancreas xref: VHOG:0000448 ! pancreas head xref: MA:0000122 ! pancreas head xref: EHDAA2:0001374 ! pancreas head xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Illu_pancreas_duodenum.jpg/200px-Illu_pancreas_duodenum.jpg xref: EMAPA:17507 ! head of pancreas of gland of foregut-midgut junction xref: EMAPA:18820 ! head of pancreas of gland of gut is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001264 ! pancreas relationship: develops_from UBERON:0003924 {source="WP", source="EHDAA2-inferred"} ! ventral pancreatic bud xref: ncithesaurus:Head_of_the_Pancreas ! Head of the Pancreas xref: SCTID:362201006 ! Entire head of pancreas synonym: "caput pancreatis" RELATED LATIN [Wikipedia:Head_of_pancreas] xref: http://upload.wikimedia.org/wikipedia/commons/f/fe/Illu_pancreas_duodenum.jpg property_value: homology_notes "Hagfish and lampreys may have one or more endocrine buds - and later the vertebrate pancreas develop as independent ventral and dorsal buds that eventually fuse to become one organ.[well established][VHOG]" xsd:string {external_class="VHOG:0000448", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD\, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. Comptes Rendus Biologies (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0227579 [Term] id: UBERON:0010373 ! uncinate process of pancreas name: uncinate process of pancreas def: "In the head of the pancreas, the angle of junction of the lower and left lateral borders forms a prolongation, termed the uncinate process. During the embryonic development of the distal foregut, the duodenum c-shape is formed while rotating the ventral pancreatic bud into the dorsal bud. The dorsal and ventral pancreatic buds fuse. The dorsal pancreatic bud becomes the body, tail, and isthmus of the pancreas and the ventral pancreatic bud forms the pancreatic head and uncinate process[WP]" [Wikipedia:Uncinate_process_of_pancreas] synonym: "lesser pancreas" EXACT [FMA:15857] synonym: "processus uncinatus (pancreas)" EXACT [FMA:15857] synonym: "Winslow's pancreas" EXACT [FMA:15857] is_a: UBERON:0004529 {source="FMA"} ! anatomical projection relationship: part_of UBERON:0001069 {source="FMA"} ! head of pancreas relationship: develops_from UBERON:0003924 {source="Wikipedia"} ! ventral pancreatic bud xref: FMA:15857 ! uncinate process of pancreas xref: SCTID:245383008 ! Entire uncinate process of pancreas xref: EMAPA:18823 ! uncinate process of head of pancreas of gland of gut xref: ncithesaurus:Uncinate_Pancreas ! uncinate process of pancreas synonym: "processus uncinatus pancreatis" RELATED LATIN [Wikipedia:Uncinate_process_of_pancreas] xref: http://upload.wikimedia.org/wikipedia/commons/f/fe/Illu_pancreas_duodenum.jpg xref: UMLS:C0227580 [Term] id: UBERON:0005604 name: hepatic duct extrahepatic part xref: MA:0001636 ! hepatic duct extrahepatic part xref: EHDAA2:0000742 ! hepatic duct extrahepatic part xref: EMAPA:16844 ! extrahepatic part of hepatic duct of liver and biliary system xref: VHOG:0000215 ! extrahepatic part of the hepatic duct xref: EHDAA:3051 ! extrahepatic part of hepatic duct is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube relationship: part_of UBERON:0005171 ! hepatic duct relationship: part_of UBERON:0003703 ! extrahepatic bile duct synonym: "extrahepatic part of the hepatic duct" EXACT [VHOG:0000215] [Term] id: UBERON:0005605 name: hepatic duct intrahepatic part xref: MA:0001637 ! hepatic duct intrahepatic part xref: EHDAA2:0000743 ! hepatic duct intrahepatic part xref: EMAPA:16845 ! intrahepatic part of hepatic duct of liver and biliary system xref: VHOG:0000216 ! intrahepatic part of the hepatic duct xref: EHDAA:3053 ! intrahepatic part of hepatic duct is_a: UBERON:0007501 {source="EHDAA2"} ! arborizing epithelial duct system relationship: part_of UBERON:0005171 ! hepatic duct relationship: part_of UBERON:0003704 ! intrahepatic bile duct synonym: "intrahepatic part of the hepatic duct" EXACT [VHOG:0000216] [Term] id: UBERON:0000020 name: sense organ def: "An organ that is capable of detection of chemical stimulus involved in sensory perception of smell." [UBERON:cjm] subset: uberon_slim synonym: "sensillum" NARROW [WBbt:0006929] synonym: "sensor" RELATED [] synonym: "sensory organ" EXACT [] synonym: "organ of sense organ system" EXACT [OBOL:accepted] synonym: "organ of sensory organ system" EXACT [OBOL:accepted] synonym: "organ of sensory system" EXACT [OBOL:accepted] synonym: "sense organ system organ" EXACT [OBOL:automatic] synonym: "sensory organ system organ" EXACT [OBOL:automatic] synonym: "sensory system organ" EXACT [OBOL:accepted] synonym: "Sinnesorgan" RELATED [BTO:0000202] xref: BTO:0000202 xref: EHDAA:500 ! sensory organ xref: FBbt:00005155 ! sense organ xref: GAID:63 ! sense organ xref: HAO:0000930 ! sense organ xref: VHOG:0001407 ! sensory organ xref: WBbt:0006929 ! sensillum xref: MA:0000017 ! sensory organ xref: EHDAA2:0001824 ! sensory organ xref: AEO:0000094 ! sense organ xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Gray722.png/200px-Gray722.png xref: EMAPA:16192 ! sensory organ xref: MESH:A09 ! sense organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: part_of UBERON:0001032 ! sense organ system xref: SCTID:244485009 ! Entire sensory organ xref: ncithesaurus:Organ_of_the_Special_Sense ! organ of special sense xref: UMLS:C0935626 [Term] id: UBERON:0004090 name: periorbital region def: "." [HP:0000606] comment: AO notes: does not contain any subparts in FMA. In HP covers eyelid, eyebrow, soft tissue synonym: "periorbital area" EXACT [MA:0002875] synonym: "periorbita" EXACT [FMA:59351] xref: MA:0002875 ! periorbital area xref: FMA:59351 ! Periorbita is_a: UBERON:0000477 ! anatomical cluster relationship: surrounds UBERON:0004867 ! orbital cavity relationship: part_of UBERON:0001456 ! face relationship: has_part UBERON:0002515 ! periosteum xref: SCTID:362646004 ! Entire periorbital region [Term] id: UBERON:0004088 ! ocular region name: ocular region def: "." [HP:0000284] comment: TODO: consider the following: eyeball (eye proper) part_of eye (= eyeball+eyelid etc) part_of ocular region (= eye + adnexa such as eyebrow); note the FMA class is more narrow though, and is more like eye + muscles + vasculature // in HP covers eyelid, eyebrow. synonym: "content of orbital part of eye" EXACT [FMA:260119] synonym: "eye region" EXACT [OBOL:accepted] synonym: "orbital content" RELATED [FMA:260119] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001456 ! face xref: FMA:260119 ! orbital content [Term] id: UBERON:0000970 name: eye def: "An organ that detects light." [http://en.wikipedia.org/wiki/Eye, UBERON:cjm, Wikipedia:Eye] comment: Usage notes: This class encompasses a variety of light-detecting structures from different phyla with no implication of homology, from the compound insect eye to the vertebrate camera-type eye (distinct classes are provided for each). Structure notes: Note that whilst this is classified as an organ, it is in fact more of a unit composed of different structures: in Drosophila, it includes the interommatidial bristle as a part; we consider here the vertebrate eye to include the eyeball/eye proper as a part, with the eye having as parts (when present): eyelids, conjuctiva, subset: uberon_slim subset: functional_classification subset: major_organ synonym: "light-detecting organ" RELATED [] synonym: "photoreceptor" BROAD [] synonym: "visual apparatus" RELATED [EV:0100336] xref: BILA:0000017 xref: BTO:0000439 xref: EFO:0000827 ! eye xref: GAID:69 ! eye xref: MAT:0000140 ! eye xref: MIAA:0000140 ! eye xref: OpenCyc:Mx4rvViTvpwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvViTvpwpEbGdrcN5Y29ycA ! eye xref: MESH:A01.456.505.420 ! eye xref: EV:0100336 ! visual apparatus xref: FBbt:00005162 ! photoreceptor is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0002104 ! visual system relationship: capable_of GO:0009584 ! detection of visible light subset: organ_slim property_value: has_relational_adjective "optic" xsd:string [Term] id: UBERON:0000971 name: ommatidium def: "One of the small facets of the compound eye." [ISBN:3110148986, Wikipedia:Ommatidium] subset: uberon_slim synonym: "omatidium" EXACT [] xref: FBbt:00004510 ! ommatidium xref: HAO:0000666 ! ommatidium xref: MAT:0000143 ! omatidium xref: MIAA:0000143 ! omatidium xref: BTO:0001922 ! ommatidium is_a: UBERON:0002536 ! arthropod sensillum relationship: part_of UBERON:0000018 ! compound eye property_value: has_relational_adjective "ommatidial" xsd:string [Term] id: UBERON:0000018 name: compound eye def: "A light sensing organ composed of ommatidia" [FB:gg, Wikipedia:Compound_eye] subset: uberon_slim synonym: "adult compound eye" RELATED [] synonym: "insect eye" RELATED [] synonym: "Facettenauge" RELATED [BTO:0001921] synonym: "Komplexauge" RELATED [BTO:0001921] synonym: "zusammengesetztes Auge" RELATED [BTO:0001921] xref: FBbt:00004508 ! eye xref: HAO:0000217 ! compound eye xref: BTO:0001921 ! compound eye xref: TGMA:0000024 ! adult compound eye is_a: UBERON:0000970 ! eye relationship: has_part UBERON:0000971 ! ommatidium relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda subset: organ_slim [Term] id: UBERON:0010312 ! immature eye name: immature eye def: "Developing anatomical structure that develops into the eyeball and associated structures." [ZFA:0001678] synonym: "future eye" EXACT [] xref: TAO:0002201 ! immature eye intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: has_developmental_contribution_from UBERON:0003071 ! eye primordium relationship: develops_from UBERON:0003071 {evidence="definitional"} ! eye primordium xref: ZFA:0001678 ! immature eye property_value: external_definition "Multi-tissue structure that consists of the structures that develop into the retina and lens.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002201", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0000019 name: camera-type eye def: "The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field[GO]. The eye contains the following parts (when they are present in the organism): the eyeball (eye proper), the lacrimal apparatus, the conjuctival, the eyelid." [GO:0043010, UBERON:cjm] comment: AO notes: FMA distinguishes Eye (subdivision of face) which has its parts an Eyeball (organ). MA includes eyelid, conjunctiva and lacrimal apparatus as part of MA:eye - consistent with FMA - so we can infer that MA:eye is more like FMA:eye than FMA:eyeball. For other AOs this distinction is less meaningful - e.g. ZFA has no eyelid; XAO has no eyelid, but it has conjuctiva, which is considered part of the xao:eye. GO considers eyelid development part of eye development. See also notes on optic nerve - XAO, AAO and BTO consider this part of the eye. MA considers the eye muscles part of the eye, whereas FMA has a class 'orbital content' for this subset: uberon_slim subset: vertebrate_core synonym: "orbital part of face" EXACT [FMA:54448] synonym: "orbital region" RELATED [FMA:54448] synonym: "regio orbitalis" EXACT LATIN [FMA:TA, FMA:54448] synonym: "vertebrate eye" NARROW [] synonym: "camera-type eye plus associated structures" RELATED [] synonym: "eye" BROAD [FMA:54448] xref: ncithesaurus:Eye xref: NIF_GrossAnatomy:birnlex_1169 ! Eye xref: FMA:54448 ! Eye xref: EMAPA:16198 ! eye xref: AAO:0010340 ! eye xref: SCTID:181143004 ! Entire orbital region xref: VHOG:0000275 ! eye xref: EHDAA:936 ! eye xref: EHDAA2:0000484 ! eye xref: MA:0000261 ! eye xref: TAO:0000107 ! eye xref: XAO:0000179 ! eye xref: AAO:0010340 ! eye xref: ZFA:0000107 ! eye xref: BTO:0004688 ! regio orbitalis xref: OpenCyc:Mx8Ngx4rwKSh9pwpEbGdrcN5Y29ycB4rvVil5pwpEbGdrcN5Y29ycB4rvViTvpwpEbGdrcN5Y29ycA ! vertebrate eye is_a: UBERON:0000047 ! simple eye relationship: part_of UBERON:0004088 ! ocular region relationship: develops_from UBERON:0003072 {evidence="definitional"} ! optic cup relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest property_value: external_definition "A cavitated compound organ that transduces light waves into neural signals.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000107", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "eyes" RELATED PLURAL [TAO:0000107] property_value: homology_notes "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {external_class="VHOG:0000275", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0000033 ! head xref: UMLS:C0015392 [Term] id: UBERON:0010230 name: eyeball of camera-type eye def: "The camera-type eye apart from its appendages/adnexa." [Wikipedia:Globe_(human_eye)] comment: See notes for camera-type eye synonym: "eye" RELATED INCONSISTENT [] synonym: "bulbus oculi" EXACT [] synonym: "eyeball" EXACT [FMA:12513] synonym: "globe" RELATED [MIAA:0000283, HP:0100886] synonym: "eye globe" EXACT [VHOG:0001616] is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0000019 {source="FMA"} ! camera-type eye xref: FMA:12513 ! eyeball xref: MIAA:0000283 ! eyeball xref: SCTID:244486005 ! Entire eye xref: VHOG:0001616 ! eye globe [Term] id: UBERON:0000021 name: cutaneous appendage def: "Appendage that protrudes from the skin." [UBERON:cjm] comment: Examples: hair, nail (FMA); feather, claw, hoof, horn, wattle, spur, beak, scale(?), antler, bristle. Editors note: Mammary glands develop by similar mechanisms, and there is an argument for including them here (e.g. PMID:20484386), but these structures do not fit the current definition (lactiferous glands are part of the integumentary system in FMA). Note the FMA class is a subdivision of epidermis, which may be too restrictive for our purposes here. TODO: revise after definition of appendage is finalized in CARO2; in addition, verify subtypes w.r.t definition - e.g. beaks may overlap with skin of body rather than being part of it - rhamphotheca may be more appropriate synonym: "skin appendage" EXACT [FMA:71012] synonym: "epidermal appendage" NARROW [] synonym: "epidermal growth" RELATED [] subset: uberon_slim is_a: UBERON:0000026 {notes="subject to revision"} ! appendage relationship: part_of UBERON:0002416 ! integumental system relationship: attaches_to UBERON:0002097 ! skin of body xref: FMA:71012 ! skin appendage xref: SCTID:276160000 ! Entire skin appendage [Term] id: UBERON:0000022 name: feather def: "one of the epidermal growths that form the distinctive outer covering, or plumage, on birds. Feathers are formed in tiny follicles in the epidermis, or outer skin layer, that produce keratin proteins. The β-keratins in feathers, beaks and claws — and the claws, scales and shells of reptiles — are composed of protein strands hydrogen-bonded into β-pleated sheets, which are then further twisted and crosslinked by disulfide bridges into structures even tougher than the α-keratins of mammalian hair, horns and hoof. The exact signals that induce the growth of feathers on the skin are not known but it has been found that the transcription factor cDermo-1 induces the growth of feathers on skin and scales on the leg." [Wikipedia:Feather] comment: Taxon notes: They are among the characteristics that distinguish the extant Aves from other living groups. Feathers have also been noticed in those Theropoda which have been termed feathered dinosaurs. Although feathers cover most parts of the body of birds, they arise only from certain well-defined tracts on the skin. They aid in flight, thermal insulation, waterproofing and coloration that helps in communication and protection. Structure notes: The β-keratins in feathers, beaks and claws — and the claws, scales and shells of reptiles — are composed of protein strands hydrogen-bonded into β-pleated sheets, which are then further twisted and crosslinked by disulfide bridges into structures even tougher than the α-keratins of mammalian hair, horns and hoof. subset: uberon_slim xref: BTO:0000447 xref: GAID:1214 ! feather xref: MAT:0000156 ! feather xref: OpenCyc:Mx4rvVjW-5wpEbGdrcN5Y29ycA xref: EFO:0000955 ! feather xref: MESH:A13.370 ! feather xref: http://upload.wikimedia.org/wikipedia/commons/4/41/Parts_of_feather_modified.jpg is_a: UBERON:0000021 ! cutaneous appendage relationship: develops_from UBERON:0001003 ! epidermis relationship: only_in_taxon NCBITaxon:436491 ! Theropoda xref: SCTID:410027006 ! Entire feather property_value: seeAlso "http://xkcd.com/1104/" xsd:anyURI [Term] id: UBERON:0008286 name: feather calamus def: "The hollow basal portion of a feather below the vane[BTO]. At the base of the feather, the rachis expands to form the hollow tubular calamus (or quill) which inserts into a follicle in the skin. The basal part of the calamus is without vanes. This part is embedded within the skin follicle and has an opening at the base (proximal umbilicus) and a small opening on the side (distal umbilicus)[WP]." [BTO:0001608] synonym: "feather quill" RELATED [BTO:0001608] synonym: "quill" RELATED [] synonym: "calamus" BROAD [] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000022 ! feather relationship: overlaps UBERON:0011783 ! feather follicle placode xref: BTO:0001608 ! feather calamus [Term] id: UBERON:0008287 ! feather vane name: feather vane def: "Collection of feather barbs that branch from rachis" [] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0008292 ! vaned feather relationship: branch_of UBERON:0008288 ! feather rachis [Term] id: UBERON:0008288 name: feather rachis def: "A central shaft of feather, with two vanes either side." [] synonym: "feather shaft" RELATED [] synonym: "main shaft of feather" RELATED [] synonym: "rachis" BROAD [] synonym: "rachis of feather" EXACT [] is_a: UBERON:0011784 ! feather shaft relationship: part_of UBERON:0011784 ! feather shaft [Term] id: UBERON:0011784 name: feather shaft synonym: "feather shaft" EXACT [] synonym: "shaft of feather" EXACT [] synonym: "stem of feather" EXACT [] xref: SCTID:66810005 ! Feather shaft is_a: UBERON:0000025 ! tube relationship: part_of UBERON:0000022 ! feather [Term] id: UBERON:0008290 name: afterfeather is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000022 ! feather [Term] id: UBERON:0008291 name: down feather def: "A feather lacking a vane and having a rudimentary rachis and a tuft of non-interlocked barbs with elongated barbules extending from the calamus" [http://people.eku.edu/ritchisong/feather_evolution.htm, Wikipedia:Down_feather] comment: lacks vane synonym: "downy feather" EXACT [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "plumulaceous feather" EXACT [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "plumaceous feather" EXACT [http://people.eku.edu/ritchisong/feather_evolution.htm] is_a: UBERON:0000022 ! feather relationship: has_function_in GO:0001659 ! temperature homeostasis disjoint_from: UBERON:0008292 ! vaned feather [Term] id: UBERON:0008292 ! vaned feather name: vaned feather intersection_of: UBERON:0000022 ! feather intersection_of: has_part UBERON:0008287 ! feather vane def: "A feather that has_part a feather vane." [OBOL:automatic] [Term] id: UBERON:0008293 name: filoplume feather def: "A hairlike feather that grows alongside the down feathers." [http://en.wikipedia.org/wiki/Filoplume#Classification] comment: Taxon notes: In some passerines, filoplumes arise exposed beyond the contour feathers on the neck synonym: "filoplume" EXACT [] is_a: UBERON:0000022 ! feather [Term] id: UBERON:0008297 ! pennaceous feather name: pennaceous feather synonym: "pennaceous" RELATED [Wikipedia:Pennaceous_feather] synonym: "contour feather" RELATED [Wikipedia:Pennaceous_feather] def: "Pennaceous feathers are also known as contour feathers. This type of feather is present in most modern birds, and has been shown in some species of maniraptoran dinosaurs. Pennaceous feathers have a central shaft (or rachis) with vanes spreading to either side. These vanes are composed of a high number of flattened barbs, that are connected to one another with barbules. The barbules are tiny strands that criss-cross on the flattened side s of the barbs. This forms a kind of miniature velcro-like mesh that holds all the barbs together, stabilizing the vanes. Flight feathers (remiges and rectrices) are specialized types of pennaceous feathers, adapted for high loadings and often strongly asymmetric for improved flight performance[WP]." [Wikipedia:Pennaceous_feather] is_a: UBERON:0008292 ! vaned feather [Term] id: UBERON:0011793 ! flight feather name: flight feather def: "." [Wikipedia:Flight_feather] synonym: "contour feather" RELATED [http://people.eku.edu/ritchisong/feather_evolution.htm] is_a: UBERON:0008297 ! pennaceous feather relationship: has_function_in GO:0060361 ! flight [Term] id: UBERON:0011794 name: rectrix feather def: "A flight feather that lies along a single horizontal row on the rear margin of the anatomical tail. Only the central pair are attached (via ligaments) to the tail bones; the remaining rectrices are embedded into the rectricial bulbs, complex structures of fat and muscle that surround those bones. Rectrices are always paired, with a vast majority of species having six pairs. They are absent in grebes and some ratites, and greatly reduced in size in penguins" [Wikipedia:Flight_feather#Rectrices] synonym: "retrix feather" EXACT [] synonym: "retrix" EXACT [] synonym: "rectrix" EXACT [] synonym: "rectrices" EXACT PLURAL [] synonym: "retrices" EXACT PLURAL [] intersection_of: UBERON:0011793 ! flight feather intersection_of: part_of UBERON:0002415 ! tail [Term] id: UBERON:0011795 ! remex feather name: remex feather def: "A flight feather located on the posterior side of the wing" [Wikipedia:Flight_feather#Remiges] synonym: "remiges" EXACT PLURAL [] synonym: "remex" BROAD [] intersection_of: UBERON:0011793 ! flight feather intersection_of: part_of UBERON:0000024 ! forelimb wing [Term] id: UBERON:0011796 name: primary remex feather def: "A remex feather that is connected to the manus" [Wikipedia:Flight_feather#Primaries] comment: these are the longest and narrowest of the remiges (particularly those attached to the phalanges), and they can be individually rotated. These feathers are especially important for flapping flight, as they are the principal source of thrust, moving the bird forward through the air. Most thrust is generated on the downstroke of flapping flight. However, on the upstroke (when the bird often draws its wing in close to its body), the primaries are separated and rotated, reducing air resistance while still helping to provide some thrust synonym: "primary remiges" EXACT PLURAL [] synonym: "primary remex" EXACT [] synonym: "primary flight feather" EXACT [] intersection_of: UBERON:0011795 ! remex feather intersection_of: connected_to UBERON:0002398 ! manus [Term] id: UBERON:0011797 name: secondary remex feather def: "A remex feather that is connected to the ulna " [Wikipedia:Flight_feather#Secondaries] comment: In some species, the ligaments that bind these remiges to the bone connect to small, rounded projections, known as quill knobs, on the ulna; in other species, no such knobs exist. Secondary feathers remain close together in flight (they cannot be individually separated like the primaries can) and help to provide lift by creating the airfoil shape of the bird's wing. Secondaries tend to be shorter and broader than primaries, with blunter ends synonym: "secondary remiges" EXACT PLURAL [] synonym: "secondary remex" EXACT [] synonym: "secondary flight feather" EXACT [] intersection_of: UBERON:0011795 ! remex feather intersection_of: connected_to UBERON:0001424 ! ulna [Term] id: UBERON:0011798 name: tertial remex feather def: "A remex feather that is connected to the humerus." [Wikipedia:Flight_feather#Tertials] comment: ertials are connected to the humerus in some species. These elongated "true" tertials act as a protective cover for all or part of the folded primaries and secondaries, and do not qualify as flight feathers as such.[11] However, many authorities use the term tertials to refer to the shorter, more symmetrical innermost secondaries of passerines (which perform the same function as true tertials) in an effort to distinguish them from the other secondaries. synonym: "tertiary remiges" EXACT PLURAL [] synonym: "tertiary remex" EXACT [] synonym: "tertiary flight feather" EXACT [] synonym: "tertial remiges" EXACT PLURAL [] synonym: "tertial remex" EXACT [] synonym: "tertial flight feather" EXACT [] intersection_of: UBERON:0011795 ! remex feather intersection_of: connected_to UBERON:0000976 ! humerus [Term] id: UBERON:0011799 ! cavity of feather shaft name: cavity of feather shaft intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: part_of UBERON:0011784 ! feather shaft def: "An anatomical cavity that is part of a feather shaft." [OBOL:automatic] [Term] id: UBERON:0011800 name: dermal pulp of feather shaft intersection_of: UBERON:0000479 ! tissue intersection_of: part_of UBERON:0011784 ! feather shaft relationship: located_in UBERON:0011799 ! cavity of feather shaft relationship: develops_from UBERON:0011803 ! feather bud, dermal component def: "A tissue that is part of a cavity of feather shaft." [OBOL:automatic] [Term] id: UBERON:0008294 ! feather barb name: feather barb synonym: "barb" BROAD SENSU [] def: "One of a series of branches fused to the rachis (stem) of a feather. The barbs themselves also have branches called barbules, which have hooks that lock the barbs together[WP]." [Wikipedia:Barb_(feather)] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0000022 ! feather relationship: branch_of UBERON:0011784 ! feather shaft [Term] id: UBERON:0011785 name: ramus of feather barb synonym: "barb ramus" RELATED [] synonym: "main shaft of feather barb" EXACT [] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0008294 ! feather barb [Term] id: UBERON:0011786 name: ramus of feather barbule synonym: "barb ramus" RELATED [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "main shaft of feather barbule" EXACT [] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0008295 ! feather barbule [Term] id: UBERON:0008295 ! feather barbule name: feather barbule def: "Projection from feather bard." [] synonym: "barbule" BROAD SENSU [] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0000022 ! feather relationship: branch_of UBERON:0008294 ! feather barb [Term] id: UBERON:0012127 name: feather barbicel def: "A minute hook that projects off of a feather barbule, holding barbules together" [] synonym: "barbicel" BROAD SENSU [] synonym: "hooklet" BROAD SENSU [] synonym: "feather hooklet" EXACT [] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0000022 ! feather relationship: branch_of UBERON:0008295 ! feather barbule [Term] id: UBERON:0011782 ! feather follicle name: feather follicle def: "a small tubular invagination of the skin with a fleshy dermal papilla at the bottom from which the feather grows. The papilla is inserted in the opening at the end of the quill[TMD]. Forms by invagination of cylinder of epidermal tissue at base of feather bud." [http://medical-dictionary.thefreedictionary.com/feather+follicle, http://people.eku.edu/ritchisong/feather_evolution.htm] comment: The follicle consists of a series of tissue layers (from peripheral to central), including the dermis of the follicle, the epidermis of the follicle (outer epidermal layer), the follicle cavity or lumen (the space between epidermal layers), the follicle (epidermal) collar (or inner epidermal layer), and the dermal pulp (tissue at the center of the follicle). The proliferation of feather keratinocytes and most of the growth of the feather occurs in the follicle, or epidermal, collar (From: Prum 1999). is_a: UBERON:0000481 ! multi-tissue structure relationship: overlaps UBERON:0000022 ! feather relationship: overlaps UBERON:0001003 ! epidermis relationship: overlaps UBERON:0002067 ! dermis relationship: develops_from UBERON:0011783 ! feather follicle placode xref: SCTID:68922000 ! Feather follicle [Term] id: UBERON:0011783 ! feather follicle placode name: feather follicle placode def: "an epidermal thickening above a condensation of dermal cells that will give rise to a feather follicle" [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "feather placode" EXACT [] synonym: "feather bud primordium" EXACT [PMID:16172986] synonym: "feather primordium" EXACT [] is_a: UBERON:0011817 ! follicle placode intersection_of: UBERON:0001048 ! primordium intersection_of: develops_into UBERON:0011782 ! feather follicle relationship: part_of UBERON:0001003 ! epidermis xref: http://people.eku.edu/ritchisong/554images/Feather_follicle_development)v3.jpg [Term] id: UBERON:0011801 ! dermal condensation of feather follicle name: dermal condensation of feather follicle def: "A suprabasal cell population which together with the feather follicle placode develops into the feather follicle." [http://people.eku.edu/ritchisong/feather_evolution.htm] comment: Taxon notes: The development of placodes where dermal condensations occur, an evolutionary novelty, required changes in gene expression and timing. However, such changes are known to be an important mechanism in the origin of morphological innovations in many other organisms (True and Carroll 2002, Prum 2005) intersection_of: UBERON:0011585 ! cell condensation intersection_of: part_of UBERON:0002067 ! dermis intersection_of: adjacent_to UBERON:0011783 ! feather follicle placode [Term] id: UBERON:0011802 ! feather bud name: feather bud def: "." [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "feather papilla" EXACT [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "elongate feather bud" EXACT [http://people.eku.edu/ritchisong/feather_evolution.htm] is_a: UBERON:0005423 ! developing anatomical structure relationship: has_part UBERON:0011803 ! feather bud, dermal component relationship: has_part UBERON:0011804 ! feather bud, epidermal component [Term] id: UBERON:0011803 ! feather bud, dermal component name: feather bud, dermal component def: "The part of the feather bud formed by a proliferation of dermal cells" [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "dermal papilla" BROAD [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "dermal papilla of feather bud" EXACT [] synonym: "dermal papilla of feather papilla" EXACT [] synonym: "dermal core of feather papilla" EXACT [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0011802 ! feather bud relationship: develops_from UBERON:0011801 ! dermal condensation of feather follicle [Term] id: UBERON:0011804 ! feather bud, epidermal component name: feather bud, epidermal component synonym: "feather bud epithelium" EXACT [] synonym: "feather germ" RELATED [http://people.eku.edu/ritchisong/feather_evolution.htm] intersection_of: UBERON:0005153 ! epithelial bud intersection_of: part_of UBERON:0011802 ! feather bud relationship: develops_from UBERON:0011783 ! feather follicle placode def: "An epithelial bud that is part of a feather bud." [OBOL:automatic] [Term] id: UBERON:0011805 name: cavity of feather follicle def: "." [http://people.eku.edu/ritchisong/feather_evolution.htm] intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: part_of UBERON:0011782 ! feather follicle [Term] id: UBERON:0011806 name: dermis of feather follicle intersection_of: UBERON:0000479 ! tissue intersection_of: part_of UBERON:0011782 ! feather follicle intersection_of: part_of UBERON:0002067 ! dermis relationship: develops_from UBERON:0011804 ! feather bud, epidermal component def: "A tissue that is part of a dermis and is part of a feather follicle." [OBOL:automatic] [Term] id: UBERON:0011807 ! epidermis of feather follicle name: epidermis of feather follicle intersection_of: UBERON:0000479 ! tissue intersection_of: part_of UBERON:0011782 ! feather follicle intersection_of: part_of UBERON:0001003 ! epidermis relationship: develops_from UBERON:0011804 ! feather bud, epidermal component def: "A tissue that is part of a epidermis and is part of a feather follicle." [OBOL:automatic] [Term] id: UBERON:0011808 name: outer epidermal layer of feather follicle is_a: UBERON:0011807 ! epidermis of feather follicle [Term] id: UBERON:0011809 name: inner epidermal layer of feather follicle comment: The proliferation of feather keratinocytes and most of the growth of the feather occurs here synonym: "epidermal collar" BROAD [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "epidermal collar of feather follicle" EXACT [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "follicle collar" BROAD [http://people.eku.edu/ritchisong/feather_evolution.htm] synonym: "follicle collar of feather follicle" EXACT [http://people.eku.edu/ritchisong/feather_evolution.htm] is_a: UBERON:0011807 ! epidermis of feather follicle relationship: site_of GO:0043616 ! keratinocyte proliferation [Term] id: UBERON:0011792 name: feather muscle def: "Similar to erector pili muscles of mammals; attached to the sides of the follicle; capable of elevating or lowering entire groups of feathers." [http://medical-dictionary.thefreedictionary.com/feather+follicle] is_a: UBERON:0004253 ! skin muscle relationship: attaches_to UBERON:0011782 ! feather follicle [Term] id: UBERON:0013512 ! row of feathers name: row of feathers is_a: UBERON:0000477 ! anatomical cluster relationship: composed_primarily_of UBERON:0000022 ! feather [Term] id: UBERON:0013513 name: anal pterya def: "two row of feathers encircling the cloaca" [http://caiquesite.com/glossary.htm] synonym: "cloacal circlet" RELATED [http://caiquesite.com/glossary.htm] intersection_of: UBERON:0013512 ! row of feathers intersection_of: surrounds UBERON:0000162 ! cloaca [Term] id: UBERON:0000023 name: wing def: "Appendage that is used to produce lift for flight through the air." [Wikipedia:Wing] comment: This class is not monophyletic. See also: GO:0007629 subset: uberon_slim subset: grouping_class xref: EFO:0000885 ! wing xref: GAID:1217 ! wing xref: MAT:0000202 ! wing xref: MIAA:0000202 ! wing xref: BTO:0001463 ! wing xref: MESH:A13.395.823 ! wing is_a: UBERON:0000026 ! appendage relationship: has_function_in GO:0060361 ! flight relationship: confers_advantage_in ENVO:00000568 ! aerial habitat property_value: has_relational_adjective "alar" xsd:string [Term] id: UBERON:0000024 name: forelimb wing def: "Forelimb that is used to produce lift for flight through the air." [] synonym: "wing wing" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] comment: Examples: bat wing, bird wing is_a: UBERON:0000023 ! wing is_a: UBERON:0002102 ! forelimb relationship: homologous_to UBERON:0002102 ! forelimb [Term] id: UBERON:0000026 name: appendage def: "Major subdivision of an organism that protrudes from the body[DOS]. Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified]. An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs[BILA]." [GO:0048736, BILA:0000018, Wikipedia:Appendage] comment: GO includes tree trunks, but excludes antennae. We modify trunk to body in our definition. Note this is currently a subtype of organism subdivision - which would exclude feathers subset: uberon_slim synonym: "limbs/digits/tail" RELATED [MP:0000001] synonym: "extremity" RELATED [] synonym: "Extremitaet" RELATED [BTO:0001492] xref: CARO:0010003 xref: BILA:0000018 xref: EFO:0000799 ! appendage xref: HAO:0000144 ! appendage xref: MAT:0000023 ! appendage xref: OpenCyc:Mx4rvViC-JwpEbGdrcN5Y29ycA xref: ncithesaurus:Appendage ! Appendage xref: OpenCyc:Mx4rvViC-JwpEbGdrcN5Y29ycA ! appendage xref: EHDAA2:0003193 ! appendage xref: AEO:0000193 ! appendage xref: MIAA:0000023 ! appendage xref: FBbt:00007000 ! appendage xref: XAO:0000218 ! appendage xref: EV:0100155 ! appendages xref: VSAO:0000075 ! appendage xref: BTO:0001492 ! limb xref: MESH:A01.378 ! extremity is_a: UBERON:0000475 ! organism subdivision property_value: has_relational_adjective "appendicular" xsd:string xref: UMLS:C0598782 [Term] id: UBERON:0010758 ! appendage segment name: appendage segment is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000026 ! appendage xref: FBbt:00007018 ! appendage segment [Term] id: UBERON:0005059 name: obsolete Drosophila lymph gland comment: out of scope is_obsolete: true [Term] id: UBERON:0000029 name: lymph node def: "Oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system. Lymph nodes are garrisons of B, T, and other immune cells. Lymph nodes are found all through the body, and act as filters or traps for foreign particles. They contain white blood cells that use oxygen to process. Thus they are important in the proper functioning of the immune system. The lymph node is surrounded by a fibrous capsule, and inside the lymph node the fibrous capsule extends to form trabeculae. The substance of the lymph node is divided into the outer cortex and the inner medulla surrounded by the former all around except for at the hilum, where the medulla comes in direct contact with the surface. Thin reticular fibers, elastin and reticular fibers form a supporting meshwork called reticular network (RN) inside the node, within which the white blood cells (WBCs), most prominently, lymphocytes are tightly packed as follicles in the cortex. Elsewhere, there are only occasional WBCs. The RN provides not just the structural support, but also provide surface for adhesion of the dendritic cells, macrophages and lymphocytes. It allows for exchange of material with blood through the high endothelial venules and provides the growth and regulatory factors necessary for activation and maturation of immune cells[WP]." [GAID:947, Wikipedia:Lymph_node] subset: uberon_slim subset: vertebrate_core xref: BTO:0000784 xref: EFO:0000872 ! lymph node xref: FMA:5034 ! Lymph node xref: GAID:947 ! lymph node xref: VHOG:0001273 ! lymph node xref: MA:0000139 ! lymph node xref: MAT:0000442 ! lymph node xref: ncithesaurus:Lymph_Node ! Lymph Node xref: OpenCyc:Mx4rwLPqLpwpEbGdrcN5Y29ycA ! lymph node xref: ZFA:0005318 ! lymph node xref: MESH:A15.382.520.604.412 ! lymph node xref: EV:0100050 ! lymph node is_a: UBERON:0000064 ! organ part relationship: continuous_with UBERON:0001473 ! lymphatic vessel relationship: has_part UBERON:0002391 ! lymph relationship: part_of UBERON:0002465 ! lymphoid system relationship: never_in_taxon NCBITaxon:8570 {source="Wikipedia"} ! Serpentes relationship: dubious_for_taxon NCBITaxon:32443 {source="ZFA", source="doie:10.1177/0192623311409597"} ! Teleostei xref: galen:Lymphnode xref: SCTID:181756000 ! Entire lymph node xref: TAO:0005318 ! lymph node synonym: "nodus lymphaticus" RELATED LATIN [Wikipedia:Lymph_node] xref: http://upload.wikimedia.org/wikipedia/commons/b/b8/Illu_lymph_node_structure.png synonym: "lymph gland" RELATED [VHOG:0001273] property_value: homology_notes "Lymph nodes that are associated with the lymphatic system have evolved in mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0001273", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.630", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0024204 [Term] id: UBERON:0007644 ! thoracic lymph node name: thoracic lymph node def: "A lymph node that is part of a thorax. Includes lymph nodes of the lungs and mediastinal lymph nodes" [OBOL:automatic, Wikipedia:Lymph_node#Lymph_nodes_of_the_thorax] synonym: "lymph node of thorax" EXACT [FMA:12772] xref: FMA:12772 ! thoracic lymph node is_a: UBERON:0000029 {source="FMA"} ! lymph node intersection_of: UBERON:0000029 ! lymph node intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk xref: ncithesaurus:Thoracic_Lymph_Node ! Thoracic Lymph Node xref: SCTID:196374005 ! Entire lymph node of thorax xref: UMLS:C0229745 [Term] id: UBERON:0005334 ! oral lamina propria name: oral lamina propria synonym: "lamina propria of oral mucosa" EXACT [] xref: EMAPA:26947 ! oral lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0003343 ! mucosa of oral region def: "A lamina propria that is part of a mucosa of oral region." [OBOL:automatic] [Term] id: UBERON:0000031 name: lamina propria of trachea synonym: "trachea lamina propria" EXACT [] synonym: "tracheal lamina propria" EXACT [] synonym: "lamina propria mucosa of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria of windpipe" EXACT [OBOL:automatic] synonym: "trachea lamina propria mucosa" EXACT [OBOL:automatic] synonym: "trachea lamina propria mucosae" EXACT [OBOL:automatic] synonym: "windpipe lamina propria" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosa" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosae" EXACT [OBOL:automatic] xref: MA:0001858 ! trachea lamina propria xref: ncithesaurus:Trachea_Lamina_Propria ! Trachea Lamina Propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001005 ! trachea relationship: part_of UBERON:0001005 ! trachea def: "A lamina propria that is part of a respiratory airway." [OBOL:automatic] relationship: part_of UBERON:0000379 {is_inferred="true", source="reference_0000032"} ! tracheal mucosa xref: UMLS:C1710457 [Term] id: UBERON:0000033 name: head def: "The head is the anterior-most division of the body [GO]." [Wikipedia:Head, GO:0060322] subset: uberon_slim subset: vertebrate_core synonym: "cephalic area" RELATED [SPD:0000016] synonym: "adult head" NARROW [] synonym: "head (volume)" EXACT [FMA:7154] xref: BILA:0000115 xref: BTO:0000282 xref: FBbt:00000004 ! head xref: FMA:7154 ! Head xref: GAID:61 ! head xref: galen:Head xref: HAO:0000397 ! head xref: MA:0000023 ! head xref: MAT:0000294 ! head xref: MIAA:0000294 ! head xref: NIF_GrossAnatomy:birnlex_1230 ! Head xref: OpenCyc:Mx4rvVi6YJwpEbGdrcN5Y29ycA xref: TAO:0001114 ! head xref: WBbt:0005739 ! head xref: XAO:0003024 ! head xref: ZFA:0001114 ! head xref: ncithesaurus:Head ! Head xref: EFO:0000964 ! head xref: OpenCyc:Mx4rEOLm4rgPEdmAAAACs6hRjg ! heading xref: EHDAA2:0003106 ! head xref: AEO:0000106 ! head xref: TGMA:0000002 ! adult head xref: MESH:A01.456 ! head xref: SPD:0000016 ! cephalic area xref: VHOG:0001644 ! head is_a: UBERON:0011676 ! axial subdivision of organism relationship: part_of UBERON:0000153 ! anterior region of body relationship: part_of UBERON:0007811 ! craniocervical region relationship: spatially_disjoint_from UBERON:0002100 ! trunk relationship: spatially_disjoint_from UBERON:0000948 ! heart xref: AAO:0010335 ! head xref: SCTID:302548004 ! Entire head property_value: external_definition "Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010335", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Organism subdivision which is the part of the body which consists of the cranial and pharygeal regions.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001114", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Vertebrate evolution has been characterized by a fresh and vast array of cranial structures that collectively form the head.[well established][VHOG]" xsd:string {external_class="VHOG:0001644", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.82", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0018670 [Term] id: UBERON:0008816 ! embryonic head name: embryonic head intersection_of: UBERON:0000033 ! head intersection_of: part_of UBERON:0000922 ! embryo xref: FBbt:00000155 ! embryonic head def: "A head that is part of a embryo." [OBOL:automatic] [Term] id: UBERON:0000035 name: primary ovarian follicle synonym: "folliculus ovaricus primarius" EXACT [] synonym: "preantral follicle of ovary" EXACT [] synonym: "primary egg follicle" RELATED [] synonym: "primary follicle of ovary" EXACT [FMA:18634] synonym: "ovary primary follicle" EXACT [MA:0002907] xref: FMA:18634 ! Primary follicle of ovary xref: MA:0002907 ! ovary primary follicle xref: BTO:0000410 ! immature ovarian follicle xref: EMAPA:19284 ! primary follicle is_a: UBERON:0001305 ! follicle of ovary xref: SCTID:258665002 ! Entire primary ovarian follicle [Term] id: UBERON:0000036 name: secondary ovarian follicle synonym: "antral follicle of ovary" EXACT [] synonym: "antral ovarian follice" EXACT [GO:0001547] synonym: "antral follice" EXACT [GO:0001547] synonym: "folliculus ovaricus secondarius" EXACT [] synonym: "secondary egg follicle" RELATED [] synonym: "secondary follicle of ovary" EXACT [] synonym: "ovary secondary follicle" EXACT [MA:0002908] synonym: "ovary antral follicle" EXACT [MA:0002909] xref: FMA:18637 ! Secondary follicle of ovary xref: MA:0002908 ! ovary secondary follicle xref: MA:0002909 ! ovary antral follicle xref: EMAPA:29862 ! secondary follicle is_a: UBERON:0001305 ! follicle of ovary relationship: develops_from UBERON:0000035 ! primary ovarian follicle [Term] id: UBERON:0000037 name: tertiary ovarian follicle def: "Ovarian follicle is the basic unit of female reproductive biology and is composed of roughly spherical aggregations of cells found in the ovary. They contain a single oocyte (aka ovum or egg). These structures are periodically initiated to grow and develop, culminating in ovulation of usually a single competent oocyte. These eggs/ova are only developed once every menstrual cycle (i. e, once a month). [WP,unvetted]." [Wikipedia:Graafian_follicle] subset: uberon_slim synonym: "folliculus ovaricus tertiarius" EXACT [] synonym: "folliculus ovaricus tertiarius (vesiculous)" EXACT [] synonym: "Graafian follicle" EXACT [] synonym: "tertiary egg follicle" RELATED [] synonym: "tertiary follicle of ovary" EXACT [FMA:18641] synonym: "folliculus ovaricus tertiarius (vesiculosus)" EXACT [FMA:18641] synonym: "vesicular follicle of ovary" EXACT [FMA:18641] synonym: "vesicular ovarian follicle" EXACT [FMA:18641] xref: FMA:18641 ! Tertiary follicle of ovary xref: ncithesaurus:Graafian_Follicle ! Graafian Follicle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Primary_follicle-4.JPG/200px-Primary_follicle-4.JPG xref: EMAPA:30763 ! tertiary follicle is_a: UBERON:0001305 ! follicle of ovary relationship: develops_from UBERON:0000036 ! secondary ovarian follicle synonym: "folliculi ovarici vesiculosi" EXACT LATIN [FMA:TA, FMA:18641] xref: SCTID:362261008 ! Entire vesicular ovarian follicle xref: UMLS:C0600225 [Term] id: UBERON:0000038 name: follicular fluid def: "The fluid surrounding the OVUM and GRANULOSA CELLS in the Graafian follicle ( OVARIAN FOLLICLE). The follicular fluid contains sex steroids, glycoprotein hormones, plasma proteins, mucopolysaccharides, and enzymes." [MESH:D015571, Wikipedia:Follicular_fluid] comment: Follicular fluid is a liquid which fills the follicular antrum and surrounds the ovum in an ovarian follicle. This fluid is rich in hyaluronic acid. subset: uberon_slim synonym: "antral fluid, ovarian follicle" RELATED [] synonym: "liquor folliculi" EXACT [] synonym: "liquor follicularis" EXACT [FMA:18665] synonym: "ovarian follicular fluid" RELATED [BTO:0004383] synonym: "ovary follicular fluid" RELATED [BTO:0004383] synonym: "ovary follicle fluid" EXACT [MA:0002511] xref: GAID:372 ! follicular fluid xref: FMA:18665 ! Liquor folliculi xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/81/Gray3.png/200px-Gray3.png xref: BTO:0004383 ! follicular fluid xref: MA:0002511 ! ovary follicle fluid xref: MESH:A05.360.319.114.630.535.150 ! follicular fluid xref: ncithesaurus:Ovarian_Follicle_Fluid ! Ovarian Follicle Fluid is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0001305 ! follicle of ovary relationship: located_in UBERON:0000039 ! follicular antrum relationship: surrounds CL:0000025 ! egg relationship: has_part CHEBI:17089 ! glycoprotein synonym: "liquor folliculi" RELATED LATIN [Wikipedia:Follicular_fluid] xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Gray3.png xref: UMLS:C1709369 [Term] id: UBERON:0000039 name: follicular antrum def: "Region of ovarian follicle filled with follicular fluid." [http://en.wikipedia.org/wiki/Follicular_antrum, Wikipedia:Follicular_antrum] subset: uberon_slim synonym: "antral cavity" EXACT [FMA:18675] synonym: "antrum folliculare" EXACT [FMA:18675] xref: FMA:18675 ! Antral cavity is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0001305 ! follicle of ovary synonym: "antrum follicularum" RELATED LATIN [Wikipedia:Follicular_antrum] [Term] id: UBERON:0000040 ! Leydig's organ name: Leydig's organ def: "A hemopoietic organ found in elasmobranchs. Along with the spleen and special tissue around the gonads, this structure produces red blood cells and it is nestled along the top and bottom of the esophagus." [http://www.elasmo-research.org/education/topics/p_blood_cells.htm, Wikipedia:Leydig's_organ] comment: Taxon notes: Found in elasmobranchs (sharks and rays) but with some exceptions. Phenotype notes: Leydig's organ can be quite large - a 1.6-kilogram (3.5-pound) one was reported from a 1.8-metre (6-foot) long Bluntnose Sixgill Shark (Hexanchus griseus). Structure notes: divided into dorsal and ventral patches, gradation varies between species. Lacks erythroblasts and fat cells[Honma 1983] subset: uberon_slim is_a: UBERON:0004177 ! hemopoietic organ relationship: only_in_taxon NCBITaxon:7778 {source="Wikipedia"} ! Elasmobranchii relationship: never_in_taxon NCBITaxon:7863 {source="Wikipedia"} ! Holocephali relationship: part_of UBERON:0002405 ! immune system relationship: composed_primarily_of CL:0000738 {source="Honma1983"} ! leukocyte [Term] id: UBERON:0010014 name: epigonal organ def: "An elongate paired tissue ventral to the kidneys and partialy enveloping the anterior gonads in Elasmobranchii. Apparently important to the immune system" [http://www.fishbase.org/glossary/Glossary.php?q=epigonal+organ] synonym: "subgonal organ" EXACT [] is_a: UBERON:0004177 ! hemopoietic organ relationship: only_in_taxon NCBITaxon:7778 {source="Wikipedia"} ! Elasmobranchii relationship: never_in_taxon NCBITaxon:7863 {source="Wikipedia"} ! Holocephali relationship: part_of UBERON:0002405 ! immune system relationship: composed_primarily_of CL:0000738 {source="Honma1983"} ! leukocyte relationship: in_lateral_side_of UBERON:0000468 ! multi-cellular organism [Term] id: UBERON:0010015 name: ventral patch of Leydig's organ is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000040 ! Leydig's organ [Term] id: UBERON:0010051 name: dorsal patch of Leydig's organ is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000040 ! Leydig's organ [Term] id: UBERON:0010016 name: spiral valve of intestine def: "Coiled structure in the lumen of the small intestine that increases the length of the route through the diesgtive tract.[WP,cjm,Kardong]" [Wikipedia:Spiral_valve] synonym: "intestinal spiral valve" EXACT [] synonym: "spiral valve" BROAD [] is_a: UBERON:0003978 {source="cjm"} ! valve relationship: part_of UBERON:0002108 ! small intestine relationship: located_in UBERON:0006909 ! lumen of gut relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: never_in_taxon NCBITaxon:32523 {source="Wikipedia"} ! Tetrapoda disjoint_from: UBERON:0010017 disjoint_from: UBERON:0010018 [Term] id: UBERON:0010017 name: spiral valve of cystic duct def: "a series of crescentic folds of mucous membrane somewhat spirally arranged on the interior of the gallbladder and continuing into the cystic duct" [http://dictionary.reference.com/browse/spiral+valve, Wikipedia:Spiral_valves_of_Heister] synonym: "Heister's valve" EXACT [FMA:15855] synonym: "valve of Heister " EXACT [] synonym: "plica spiralis" EXACT LATIN [FMA:TA] synonym: "plica spiralis (ductus cysticus)" EXACT [FMA:15855] synonym: "spiral fold of cystic duct" EXACT [FMA:15855] is_a: UBERON:0003978 {source="FMA"} ! valve xref: FMA:15855 ! spiral valve of cystic duct xref: SCTID:270125000 ! Entire valve of Heister disjoint_from: UBERON:0010018 [Term] id: UBERON:0010018 name: spiral valve of conus arteriosus def: "The spiral valve alternately blocks & unblocks the entrances to the left and right pulmonary arches (sending unoxygenated blood to the skin & lungs)." [http://people.eku.edu/ritchisong/342notes9.html] comment: Taxon notes: many dipnoans and amphibians. Evolution notes: The spiral valve is considered to have evolved from the right member of the four embryonic endocardial ridges (Goodrich, 1930 - via Morris 1974) is_a: UBERON:0003978 {source="cjm"} ! valve relationship: part_of UBERON:0003983 {source="AAO"} ! conus arteriosus relationship: only_in_taxon NCBITaxon:8287 {evidence="NAS"} ! Sarcopterygii relationship: never_in_taxon NCBITaxon:32524 ! Amniota xref: AAO:0010251 ! spiral valve xref: http://cwx.prenhall.com/bookbind/pubbooks/martini10/chapter21/medialib/Kardong_fig_12_29.html [Term] id: UBERON:0010019 name: spiracle def: "a small hole behind each eye that opens to the mouth in some fish. In the primitive jawless fish the first gill opening immediately behind the mouth is essentially similar to the other gill openings." [ISBN10:0073040584, Wikipedia:Spiracle#Vertebrates] synonym: "vertebrate spiracle" EXACT [] comment: Taxon notes: The spiracle is still found in all cartilaginous fish except chimaeras, and in bony fishes in the coelacanth, sturgeon, paddlefish and bichirs. It is also seen as an otic notch in the skull of the extinct labyrinthodonts, and is thought to be associated with the ear opening in amniotes and frogs[WP]. In elasmobranchs (sharks and rays), a spiracle is found behind each eye, and is often used to pump water through the gills while the animal is at rest (Fouts, 2003). A spiracle is also found in primitive bony fishes as the chirrups. TODO - check GO:0035277-spiracle morphogenesis, open tracheal system - taxon constraint in GO is_a: UBERON:0003102 {source="cjm"} ! surface structure relationship: part_of UBERON:0001004 ! respiratory system relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: never_in_taxon NCBITaxon:32523 ! Tetrapoda [Term] id: UBERON:0013222 name: otic notch def: "Otic notches are invagination in the posterior margin of the skull roof, one behind each orbit. Such notches are found in labyrinthodonts and some of their immediate ancestors, but not their reptilian descendants. The presence or absence of the otic notches is one of the traits used to separate the amniotes from the amphibian grade tetrapods. The notches have been interpreted as part of an auditory structure, and are often shown holding a tympanum similar to those seen in modern anurans. Analysis of the columella (the stapes in amphibians and reptiles) of labyrinthodonts however indicate it did not function in transmitting low energy vibrations, thus rendering them effectively deaf to airborne sound. The otic notch instead functioned as a spiracle, at least in the early forms." [Wikipedia:Otic_notch] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0003113 ! dermatocranium [Term] id: UBERON:0001006 name: obsolete spiracle def: "OBSOLETE: The mostly slit-like opening on the body surface through which air is taken into the respiratory system." [ISBN:3110148986, Wikipedia:Spiracle] comment: This class was obsoleted as it grouped together disparate classes. For the fish structure, see UBERON:0010019. The arthropod structure will presumably be added to the arthropod anatomy synonym: "spiracular gland" RELATED [] synonym: "open tracheal system spiracle" NARROW [GO:0035277] synonym: "spiracle of open tracheal system" NARROW [GO:0035277] consider: FBbt:00005054 ! spiracle consider: HAO:0000950 ! spiracle consider: TGMA:0000578 ! spiracle xref: MAT:0000208 ! spiracle xref: MIAA:0000208 ! spiracle xref: EFO:0000936 ! spiracle is_obsolete: true consider: UBERON:0010019 [Term] id: UBERON:0004457 ! cavity lining name: cavity lining comment: Editor notes: consider merging with serous membrane. AO notes: in MA this groups pericardium, pleura and periotoneal cavity lining xref: MA:0002448 ! cavity lining is_a: UBERON:0004923 ! organ component layer is_a: UBERON:0004458 {notes="pre-inferred via union_of"} ! body cavity or lining [Term] id: UBERON:0004458 ! body cavity or lining name: body cavity or lining comment: Note that this class may be merged into 'serous sac'. See notes for 'cavity lining' xref: MA:0000005 ! body cavity or lining xref: EMAPA:16060 ! cavities and their linings is_a: UBERON:0001062 ! anatomical entity union_of: UBERON:0004457 ! cavity lining union_of: UBERON:0002323 ! coelemic cavity lumen [Term] id: UBERON:0000042 name: serous membrane def: "multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." [Wikipedia:Serous_membrane, http://purl.obolibrary.org/obo/uberon/tracker/86] comment: in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA. subset: uberon_slim subset: vertebrate_core synonym: "serosa" RELATED [Wikipedia:Serous_membrane] synonym: "tunica serosa" EXACT LATIN [FMA:9581] synonym: "wall of serous sac" EXACT [FMA:9581] xref: FMA:9581 ! Serous membrane xref: ncithesaurus:Serosa ! Serosa xref: GAID:19 ! serous membrane xref: http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png xref: ZFA:0005425 ! serous membrane xref: MESH:A10.615.789 ! serous membrane is_a: UBERON:0004457 ! cavity lining relationship: has_part UBERON:0001136 ! mesothelium relationship: has_part UBERON:0002384 ! connective tissue relationship: develops_from UBERON:0000926 {source="Wikipedia"} ! mesoderm relationship: part_of UBERON:0000060 ! anatomical wall xref: SCTID:362878009 ! Entire serous membrane xref: TAO:0005425 ! serous membrane xref: http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png property_value: external_definition "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005425", date_retrieved="2012-08-14", source="http://en.wikipedia.org/wiki/Serous_membrane"} property_value: external_definition "a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]" xsd:string {source="http://en.wikipedia.org/wiki/Serous_membrane"} xref: UMLS:C0036760 [Term] id: UBERON:0000044 name: dorsal root ganglion def: "ganglion on the dorsal root of each spinal nerve that is one of a series of ganglia lodging cell bodies of sensory neurons[BTO]. Trunk ganglion which is located adjacent to the spine on a dorsal root and contains the cell bodies of afferent sensory nerves[..]. one on the posterior root of each spinal nerve, composed of unipolar nerve cell bodies of the sensory neurons of the nerve[TFD]." [Wikipedia:Dorsal_root_ganglion] comment: Development notes: The sensory ganglia of spinal nerves arise only from the neural crest, whereas many sensory ganglia of the “dorsal” cranial nerves arise from epibranchial placodes as well as the neural crest[doi: 10.1093/icb/icn065]. Other ontology notes: FMA treats dorsal root ganglion and spinal ganglion as equivalent labels. MA is the only ontology to introduce two classes here (also EHDAA2) subset: uberon_slim subset: vertebrate_core synonym: "dorsal root ganglia" RELATED PLURAL [] synonym: "dorsal root ganglion" EXACT [BTO:0001264] synonym: "DRG" RELATED [] synonym: "ganglion spinalis" EXACT [FMA:5888] synonym: "spinal ganglion" EXACT [FMA:5888] synonym: "ganglion of dorsal root" EXACT [OBOL:automatic] synonym: "ganglion sensorium nervi spinalis" RELATED [BTO:0001264] synonym: "ganglion spinale" RELATED [BTO:0001264] xref: BTO:0001264 xref: EFO:0000900 ! dorsal root ganglion xref: EHDAA:2899 ! dorsal root ganglion xref: FMA:5888 ! Spinal ganglion xref: VHOG:0000222 ! dorsal root ganglion xref: MA:0000232 ! dorsal root ganglion xref: MA:0000231 ! spinal ganglion xref: MAT:0000162 ! dorsal root ganglion xref: MIAA:0000162 ! dorsal root ganglion xref: NIF_GrossAnatomy:birnlex_2596 ! Dorsal root ganglion xref: TAO:0000200 ! dorsal root ganglion xref: XAO:0000210 ! spinal ganglion xref: ZFA:0000200 ! dorsal root ganglion xref: ncithesaurus:Dorsal_Root_Ganglion ! Dorsal Root Ganglion xref: EHDAA2:0000418 ! dorsal root ganglion xref: EHDAA2:0001897 ! spinal ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/71/DRG_Chicken_e7.jpg/200px-DRG_Chicken_e7.jpg xref: EMAPA:16668 ! dorsal root ganglion of ganglion of spinal xref: EMAPA:18372 ! dorsal root ganglion of ganglion of peripheral nervous system of nervous system of tail of embryo xref: EV:0100373 ! spinal ganglion is_a: UBERON:0001800 {source="MA"} ! sensory ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0002261 ! dorsal root relationship: develops_from UBERON:0003083 {source="ZFA", source="UBERONREF:0000002"} ! trunk neural crest xref: AAO:0011032 ! dorsal root ganglion xref: SCTID:244455004 ! Entire spinal nerve ganglion synonym: "ganglion sensorium nervi spinalis" RELATED LATIN [Wikipedia:Dorsal_root_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/7/71/DRG_Chicken_e7.jpg property_value: external_definition "Trunk ganglion which is located adjacent to the spine on a dorsal root and contains the cell bodies of afferent sensory nerves.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000200", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "From comparative analyses of craniate brains, a morphotype of the brain in the earliest craniate stock can be constructed. In marked contrast to cephalochordates, the ancestral craniate morphotype had a plethora of unique features, which included a telencephalon with pallial and subpallial parts, paired olfactory bulbs with substantial projections to most or all of the telencephalic pallium, paired lateral eyes and ears, a lateral line system for both electroreception and mechanoreception, spinal cord dorsal root ganglia, and an autonomic nervous system.[well established][VHOG]" xsd:string {external_class="VHOG:0000222", ontology="VHOG", source="DOI:10.1002/1097-0185(20000615)261:3<111::AID-AR6>3.0.CO;2-F Butler AB\, Chordate evolution and the origin of craniates: An old brain in a new head. AnaT Rec (New Anat) (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0017070 [Term] id: UBERON:0000125 name: neural nucleus def: "Anatomical structure consisting of a discrete aggregate of neuronal soma[GO]." [GO:0048857, GO_REF:0000021, Wikipedia:Nucleus_(neuroanatomy)] comment: do not include NIF_Subcellular:sao1702920020 Nucleus. Proposed CUMBO def from MM: A subcortical part of the nervous system consisting of a relatively compact group of cells that is distinguishable histologically that share a commonality of cytoarchitecture, chemoarchitecturel and connectivity. (comments: I put in "subcortical" because I don't think we consider either the cerebellar cortex or cerebral cortex to be nuclei. Some people distinguish between a nucleus and a laminar structure (see Wikipedia definition). However, there are structures identified as nuclei that are laminar, e.g., lateral geniculate nucleus, although they are not laminated in all species. Also, I put in "relatively compact" and "distiguishable by histology" because we have groups of cells, e.g., cholinergic cell groups, doparminergic cell groups that are related on the 3 criteria but which we don't tend to consider nuclei because they don't occupy an easily defined territory. But all is open to debate. synonym: "nucleus" BROAD [] synonym: "nucleus of neuraxis" RELATED [] synonym: "neuraxis nucleus" EXACT [FMA:83686] synonym: "neuronal nucleus" EXACT [AEO:0000136] xref: FMA:83686 ! Nucleus of neuraxis xref: AEO:0000136 ! neuronal nucleus is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001016 ! nervous system relationship: has_part GO:0043025 ! neuronal cell body [Term] id: UBERON:0002308 name: nucleus of brain def: "Nucleus of neuraxis which is located within the brain. Example: pontobulbar nucleus, globose nucleus[FMA]. brain structure consisting of a relatively compact cluster of neurons. It is one of the two most common forms of nerve cell organization, the other being layered structures such as the cerebral cortex or cerebellar cortex. In anatomical sections, a nucleus shows up as a region of gray matter, often bordered by white matter. The vertebrate brain contains hundreds of distinguishable nuclei, varying widely in shape and size. A nucleus may itself have a complex internal structure, with multiple types of neurons arranged in clumps (subnuclei) or layers.[Wikipedia]" [FMA:83840, Wikipedia:Nucleus_(neuroanatomy)] comment: We considered merging with 'neural nucleus' synonym: "brain nucleus" EXACT [] xref: FMA:83840 ! Nucleus of brain xref: MA:0000811 ! brain nucleus xref: ZFA:0005575 ! brain nucleus xref: ncithesaurus:Brain_Nucleus ! Brain Nucleus intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0003528 ! brain grey matter xref: SCTID:426465002 ! Entire nucleus of brain xref: UMLS:C1706993 [Term] id: UBERON:0000045 name: ganglion def: "A biological tissue mass, most commonly a mass of nerve cell bodies." [Wikipedia:Ganglion] comment: TODO - check vert vs invert. Other species: Any of a number of aggregations of neurons, glial cells and their processes, surrounded by a glial cell and connective tissue sheath (plural: ganglia). // Subdivision of neural tree (organ) which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord); together with a nucleus and its associated nerve, it constitutes a neural tree (organ). Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. // a cluster of nerve cells and associated glial cells (nuclear location) // Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system. // Structures containing a collection of nerve cell bodies. (Source: BioGlossary, www.Biology-Text.com). subset: uberon_slim subset: vertebrate_core synonym: "ganglia" RELATED [] synonym: "neural ganglion" RELATED [BTO:0000497] xref: BTO:0000497 xref: EFO:0000899 ! ganglion xref: EHDAA:2897 ! ganglion xref: EHDAA:4662 ! ganglion xref: EHDAA:5621 ! ganglion xref: EHDAA:918 ! ganglion xref: FBbt:00005137 ! ganglion xref: FMA:5884 ! Ganglion xref: VHOG:0000156 ! ganglion xref: MA:0002406 ! ganglion xref: MAT:0000207 ! invertebrate ganglion xref: MAT:0000343 ! ganglion xref: MIAA:0000207 ! invertebrate ganglion xref: MIAA:0000343 ! ganglion xref: NIF_GrossAnatomy:nlx_anat_100302 ! Ganglion xref: TAO:0000190 ! ganglion xref: WBbt:0005189 ! ganglion xref: XAO:0000209 ! ganglion xref: ZFA:0000190 ! ganglion xref: ncithesaurus:Ganglion ! Ganglion xref: EHDAA2:0003135 ! ganglion xref: AEO:0000135 ! ganglion xref: TGMA:0001016 ! ganglia xref: MESH:A08.340 ! ganglia xref: EV:0100372 ! ganglion is_a: UBERON:0003714 {source="EHDAA2"} ! neural tissue is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001016 ! nervous system xref: AAO:0010426 ! ganglion relationship: develops_from UBERON:0003869 {evidence="definitional"} ! presumptive ganglion property_value: external_definition "Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010426", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Structures containing a collection of nerve cell bodies. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000190", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Cranial sensory placodes are focused areas of the head ectoderm of vertebrates that contribute to the development of the cranial sense organs and their associated ganglia. Placodes have long been considered a key character of vertebrates, and their evolution is proposed to have been essential for the evolution of an active predatory lifestyle by early vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000156", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.021 Mazet F\, Hutt JA\, Milloz J\, Millard J\, Graham A\, Shimeld SM\, Molecular evidence from Ciona intestinalis for the evolutionary origin of vertebrate sensory placodes. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "ganglionic" xsd:string xref: UMLS:C0017067 [Term] id: UBERON:0003338 name: ganglion of peripheral nervous system def: "A ganglion that is part of a peripheral nervous system [Automatically generated definition]." [OBOL:automatic] comment: We follow MA in including separate classes for ganglion and peripheral nervous system, even though for vertebrates gangia are always in the PNS synonym: "peripheral nervous system ganglion" EXACT [OBOL:automatic] xref: EMAPA:18371 ! ganglion of peripheral nervous system of nervous system of tail of embryo xref: MA:0001161 ! peripheral nervous system ganglion xref: BTO:0001123 ! peripheral ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0000010 ! peripheral nervous system [Term] id: UBERON:0003339 name: ganglion of central nervous system def: "A ganglion that is part of a central nervous system [Automatically generated definition]." [OBOL:automatic] comment: this has no subclasses in FMA. In EHDAA2 it has only the cranial ganglia synonym: "central nervous system ganglion" EXACT [OBOL:automatic] synonym: "ganglion of neuraxis" EXACT [OBOL:automatic] synonym: "neuraxis ganglion" EXACT [OBOL:automatic] xref: EMAPA:16658 ! ganglion of central nervous system of nervous system of organ system xref: FMA:83843 ! Ganglion of neuraxis xref: EHDAA2:0000227 ! central nervous system ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0000046 name: stemma def: "eye-spots which may be set into a pit to reduce the angles of light that enters and affects the eyespot, to allow the organism to deduce the angle of incoming light" [Wikipedia:Eye#Pit_eyes, Wikipedia:Stemma] subset: uberon_slim synonym: "pit eye" EXACT [Wikipedia:Eye#Pit_eyes] is_a: UBERON:0000047 ! simple eye [Term] id: UBERON:0000047 name: simple eye def: "An eye with one concave chamber. Note that \'simple\' does not imply a reduced level of complexity or acuity." [Wikipedia:Eye#Simple_eyes] subset: uberon_slim subset: grouping_class xref: TGMA:0000729 ! larval stemma is_a: UBERON:0000970 ! eye [Term] id: UBERON:0000048 name: pinhole eye def: "Simple eye that has a small aperture (which may be adjustable) and deep pit. It is only found in the nautiloids." [DOI:10.1146/annurev.ne.15.030192.000245, Wikipedia:Pinhole_eye] subset: uberon_slim subset: grouping_class is_a: UBERON:0000047 ! simple eye [Term] id: UBERON:0000049 name: spherical lensed eye def: "simple eye that consists of a lens of one refractive index" [Wikipepedia:Eye#Spherical_lensed_eye] subset: grouping_class is_a: UBERON:0000047 ! simple eye [Term] id: UBERON:0000050 name: simple eye with multiple lenses def: "simple eye that has two or more lenses. Some marine organisms bear more than one lens; for instance the copeopod Pontella has three. The outer has a parabolic surface, countering the effects of spherical aberration while allowing a sharp image to be formed. Copilla's eyes have two lenses, which move in and out like a telescope" [Wikipedia:Eye#Multiple_lenses] subset: uberon_slim subset: grouping_class is_a: UBERON:0000047 ! simple eye relationship: has_part UBERON:0000965 ! lens [Term] id: UBERON:0000052 ! fornix of brain name: fornix of brain def: "The fornix (Latin, 'vault' or 'arch') is a C-shaped bundle of fibres in the brain, and carries signals from the hippocampus to the mammillary bodies and septal nuclei. [WP,unvetted]." [Wikipedia:Vaginal_fornix_of_brain_of_brain] subset: uberon_slim synonym: "cerebral fornix" EXACT [] synonym: "brain fornix" EXACT [] synonym: "fornix" BROAD [] synonym: "fornix of neuraxis" EXACT [FMA:83865] synonym: "neuraxis fornix" EXACT [FMA:83865] xref: MA:0002747 ! fornix xref: NIF_GrossAnatomy:birnlex_705 ! Fornix xref: FMA:83865 ! Fornix of neuraxis xref: ncithesaurus:Cerebral_Fornix ! Cerebral Fornix xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/21/Gray747.png/200px-Gray747.png is_a: UBERON:0002437 ! cerebral white matter xref: SCTID:279302004 ! Entire cerebral fornix xref: UMLS:C0458370 [Term] id: UBERON:0000053 name: macula lutea def: "Oval yellow spot near the center of the retina of the human eye. It has a diameter of around 5 mm and is often histologically defined as having two or more layers of ganglion cells. Near its center is the fovea, a small pit that contains the largest concentration of cone cells in the eye and is responsible for central vision, and also contains the parafovea and perifovea[WP]. It is devoid of retinal blood vessels, except in its periphery, and receives nourishment from the choriocapillaris of the choroid. (From Cline et al., Dictionary of Visual Science, 4th ed)" [Wikipedia:Macula_of_retina, MESH:A09.371.729.522] subset: uberon_slim synonym: "macula" RELATED [] synonym: "maculae" RELATED [] synonym: "macula flava retinae" RELATED [BTO:0003015] synonym: "macula retinae" RELATED [BTO:0003015] xref: FMA:58637 ! Macula lutea xref: GAID:909 ! macula lutea xref: MA:0001306 ! macula xref: NIF_GrossAnatomy:birnlex_2540 ! Macula xref: ncithesaurus:Macula ! Macula xref: ncithesaurus:Macula_Lutea ! macula lutea xref: BTO:0003015 ! macula lutea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Human_eye_cross-sectional_view_grayscale.png/200px-Human_eye_cross-sectional_view_grayscale.png xref: MESH:A09.371.729.522 ! macula lutea xref: EV:0100349 ! macula lutea is_a: UBERON:0000064 ! organ part disjoint_from: UBERON:0000054 ! macula relationship: part_of UBERON:0000966 ! retina xref: SCTID:362517001 ! Entire macula lutea xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png xref: UMLS:C0450295 [Term] id: UBERON:0000055 name: vessel comment: compare with UBERON:0008782 def: "A tubular structure that contains, conveys body fluid, such as blood or lymph." [UBERON:cjm] subset: grouping_class is_a: UBERON:0004111 ! anatomical conduit [Term] id: UBERON:0006554 name: urinary system structure comment: editor note: note that we do not explicitly exclude entities such as WBbt:0005777 (excretory duct) here, but they will be automatically classified under this class after reasoning intersection_of: UBERON:0000061 ! anatomical structure intersection_of: part_of UBERON:0001008 ! urinary system xref: SCTID:122489005 ! Urinary system structure def: "An anatomical structure that is part of a excretory system." [OBOL:automatic] [Term] id: UBERON:0006555 ! excretory tube name: excretory tube intersection_of: UBERON:0000025 ! tube intersection_of: part_of UBERON:0001008 ! urinary system def: "A tube that is part of a excretory system." [OBOL:automatic] [Term] id: UBERON:0000056 name: ureter def: "Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs. In humans, organ with organ cavity which connects the renal sinus to the urinary bladder. Examples: the right and the left ureters." [Wikipedia:Ureter, GO:0090189, FMA:9704] subset: uberon_slim subset: major_organ synonym: "metanephric duct" RELATED [VHOG:0000605, ISBN10:0073040584] xref: BTO:0001409 xref: EFO:0000930 ! ureter xref: EHDAA:9341 ! ureter xref: FMA:9704 ! Ureter xref: GAID:438 ! ureter xref: VHOG:0000605 ! ureter xref: MA:0000378 ! ureter xref: MAT:0000120 ! ureter xref: MIAA:0000120 ! ureter xref: ncithesaurus:Ureter xref: OpenCyc:Mx4rvhmm6JwpEbGdrcN5Y29ycA xref: galen:Ureter ! ureter xref: OpenCyc:Mx4rvhmm6JwpEbGdrcN5Y29ycA ! ureter xref: EHDAA2:0002139 ! ureter xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Urinary_system.svg/200px-Urinary_system.svg.png xref: XAO:0000144 ! ureter xref: EMAPA:17950 ! ureter xref: MESH:A05.810.776 ! ureter xref: EV:0100097 ! ureter is_a: UBERON:0000062 ! organ is_a: UBERON:0000025 ! tube relationship: part_of UBERON:0002355 {xref="MA:0000378"} ! pelvis relationship: part_of UBERON:0011143 {source="FMA"} ! upper urinary tract relationship: develops_from UBERON:0005081 {source="GO"} ! ureter ureteric bud relationship: channels_from UBERON:0001224 ! renal pelvis relationship: channels_into UBERON:0001255 ! urinary bladder relationship: channel_for UBERON:0001088 ! urine xref: AAO:0010254 ! ureter xref: SCTID:302511008 ! Entire ureter subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg property_value: external_definition "Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010254", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The duct of amniotes that carries urine from a metanephric kidney to the urinary bladder. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000605", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {external_class="VHOG:0000605", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.543", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0000468 ! multi-cellular organism property_value: has_relational_adjective "ureteric" xsd:string property_value: has_relational_adjective "ureteral" xsd:string xref: UMLS:C0041951 [Term] id: UBERON:0000057 name: urethra def: "A tube which connects the urinary bladder to the outside of the body. In males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter and emerges above the vaginal opening. The external urethral sphincter is a striated muscle that allows voluntary control over urination." [Wikipedia:Urethra] subset: uberon_slim subset: major_organ xref: FMA:19667 ! Urethra xref: GAID:390 ! urethra xref: VHOG:0001264 ! urethra xref: MA:0000379 ! urethra xref: MAT:0000121 ! urethra xref: MIAA:0000121 ! urethra xref: OpenCyc:Mx4rvVjkypwpEbGdrcN5Y29ycA xref: XAO:0000153 ! urethra xref: EMAPA:30901 ! urethra of urinary system xref: ncithesaurus:Urethra ! Urethra xref: BTO:0001426 ! urethra xref: EFO:0000931 ! urethra xref: galen:Urethra ! urethra xref: OpenCyc:Mx4rvVjkypwpEbGdrcN5Y29ycA ! urethra xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Female_anatomy.png/200px-Female_anatomy.png xref: MESH:A05.360.444.492.726 ! urethra xref: EV:0100099 ! urethra is_a: UBERON:0000062 ! organ relationship: continuous_with UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001556 ! lower urinary tract relationship: has_function_in GO:0060073 ! micturition relationship: develops_from UBERON:0000164 {source="Wikipedia", notes="pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra"} ! primitive urogenital sinus relationship: channels_from UBERON:0001255 ! urinary bladder relationship: channel_for UBERON:0001088 ! urine xref: SCTID:302513006 ! Entire urethra subset: organ_slim property_value: has_relational_adjective "urethral" xsd:string xref: UMLS:C0041967 [Term] id: UBERON:0010390 name: lumen of urethra synonym: "urethral lumen" EXACT [FMA:19709] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra xref: FMA:19709 ! lumen of urethra xref: SCTID:279432008 ! Entire urethral lumen def: "An organ cavity that is part of a urethra." [OBOL:automatic] [Term] id: UBERON:0000025 name: tube synonym: "epithelial or endothelial lined tube" RELATED [] xref: galen:Tube ! tube is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: has_quality PATO:0001873 ! cylindrical relationship: has_quality PATO:0001873 ! cylindrical property_value: has_relational_adjective "tubular" xsd:string [Term] id: UBERON:0013522 ! subdivision of tube name: subdivision of tube is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000025 ! tube relationship: subdivision_of UBERON:0000025 ! tube [Term] id: UBERON:0003914 name: epithelial tube def: "Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GO:0060562, PMID:12526790] synonym: "epithelial or endothelial tube" EXACT [] xref: EHDAA2:0003114 ! epithelial tube xref: AEO:0000114 ! epithelial tube xref: FBbt:00007474 ! epithelial tube is_a: UBERON:0000025 ! tube intersection_of: UBERON:0000483 ! epithelium intersection_of: has_quality PATO:0001873 ! cylindrical [Term] id: UBERON:0000058 name: duct def: "A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA]." [Wikipedia:Duct_(anatomy), ZFA:0005171] comment: TODO - make distinctions between duct and tube clearer. Single layer of cells vs multiples? Function (e.g. exocrine gland duct?). Different ontologies use it in different ways (e.g. isa epithelial tube in FBbt). Consider adding duct of gland synonym: "anatomical duct" EXACT [] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] subset: vertebrate_core xref: FMA:30320 ! Duct xref: galen:Duct xref: ZFA:0005171 ! duct xref: FBbt:00100314 ! duct xref: ncithesaurus:Duct ! Duct is_a: UBERON:0004111 ! anatomical conduit relationship: has_function_in GO:0032941 ! tissue secretion xref: XAO:0004000 ! duct xref: TAO:0005171 ! duct xref: AAO:0011123 ! duct xref: SCTID:91726008 ! Entire duct (organ) xref: UMLS:C0687028 [Term] id: UBERON:0000059 name: large intestine def: "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]." [Wikipedia:Large_intestine_(anatomy), ISBN10:0073040584] subset: major_organ synonym: "intestinum crassum" RELATED [BTO:0000706] xref: BTO:0000706 xref: EFO:0000840 ! large intestine xref: FMA:7201 ! Large intestine xref: galen:LargeIntestine xref: VHOG:0000054 ! large intestine xref: MA:0000333 ! large intestine xref: MIAA:0000046 ! large intestine xref: ncithesaurus:Large_Intestine xref: OpenCyc:Mx4rvVkF5pwpEbGdrcN5Y29ycA xref: XAO:0000131 ! large intestine xref: GAID:306 ! large intestine xref: OpenCyc:Mx4rvVkF5pwpEbGdrcN5Y29ycA ! large intestine xref: EMAPA:19252 ! large intestine xref: MESH:A03.492.411.495 ! large intestine xref: EV:0100077 ! large intestine is_a: UBERON:0000062 ! organ is_a: UBERON:0004921 {source="cjm", order="2"} ! subdivision of digestive tract relationship: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0004907 ! lower digestive tract xref: AAO:0010396 ! large intestine xref: SCTID:181254001 ! Entire large intestine subset: organ_slim property_value: homology_notes "Intestinal surface area also is increased in amphibians and reptiles by internal folds and occasionally by a few villi. The intestine can be divided into a small intestine and a slightly wider large intestine.[well established][VHOG]" xsd:string {external_class="VHOG:0000054", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.566", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0021851 [Term] id: UBERON:0000061 name: anatomical structure def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome." [CARO:0000003] subset: upper_level synonym: "biological structure" EXACT [] xref: BILA:0000003 xref: CARO:0000003 ! anatomical structure xref: FBbt:00007001 ! anatomical structure xref: FMA:67135 ! Anatomical structure xref: MA:0003000 ! anatomical structure xref: HAO:0000003 ! anatomical structure xref: TAO:0000037 ! anatomical structure xref: XAO:0003000 ! anatomical structure xref: ZFA:0000037 ! anatomical structure xref: EHDAA2:0003003 ! anatomical structure xref: AEO:0000003 ! anatomical structure xref: TGMA:0001823 ! anatomical structure xref: MESH:A13 ! animal structure xref: GAID:781 ! animal structure is_a: UBERON:0000465 ! material anatomical entity xref: AAO:0010825 ! anatomical structure xref: SCTID:362889002 ! Entire anatomical structure xref: VHOG:0001759 ! anatomical structure [Term] id: UBERON:0000062 name: organ def: "Anatomical structure that performs a specific function or group of functions [WP]. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions[GO]." [Wikipedia:Organ_(anatomy)] subset: upper_level comment: note that CARO does not include a generic 'organ' class, only simple and compound organ synonym: "body organ" RELATED [] synonym: "element" RELATED [] xref: EFO:0000634 xref: FMA:67498 ! Organ xref: MA:0003001 ! organ xref: OpenCyc:Mx4rwP3iWpwpEbGdrcN5Y29ycA xref: ncithesaurus:Organ ! Organ xref: OpenCyc:Mx4rv5XMb5wpEbGdrcN5Y29ycA ! organ xref: NIF_GrossAnatomy:birnlex_4 ! Organ is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000467 ! anatomical system relationship: never_in_taxon NCBITaxon:110815 {source="Wikipedia"} ! Xenoturbella xref: UMLS:C0178784 xref: SCTID:272625005 ! Entire body organ [Term] id: UBERON:0000064 name: organ part def: "anatomical structure which has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement. Examples: osteon, cortical bone, neck of femur, bronchopulmonary segment, left lobe of liver, anterior right side of heart, interventricular branch of left coronary artery, right atrium, mitral valve, head of pancreas[FMA]." [FMA:82472] subset: disjointness_axiom_removed subset: upper_level synonym: "cardinal organ part" EXACT [] xref: FMA:82472 ! Cardinal organ part xref: EFO:0000635 ! organism part is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000062 ! organ xref: SCTID:91717005 ! Organ part xref: AAO:0011124 ! organ part xref: SCTID:113343008 ! Body organ structure [Term] id: UBERON:0011906 ! muscle head name: muscle head subset: upper_level synonym: "caput (musculus)" EXACT [FMA:85453] synonym: "caput musculi" EXACT [FMA:85453] synonym: "muscular organ head" EXACT [FMA:85453] synonym: "head of muscle organ" EXACT [FMA:85453] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001630 ! muscle organ xref: FMA:85453 ! head of muscle organ [Term] id: UBERON:0000067 name: embryo stage part def: "A stage that is part of the embryo stage." [UBERON:cjm] synonym: "embryonic stage part" EXACT [] subset: grouping_class is_a: UBERON:0000105 ! life cycle stage intersection_of: UBERON:0000105 ! life cycle stage intersection_of: part_of UBERON:0000068 ! embryo stage relationship: part_of UBERON:0000068 ! embryo stage [Term] id: UBERON:0000068 name: embryo stage def: "A life cycle stage that starts with fertilization and ends with the fully formed embryo." [] synonym: "embryonic stage" EXACT [] synonym: "embryogenesis" RELATED [] xref: XAO:1000012 ! embryonic stage xref: FBdv:00005289 ! embryonic stage xref: OGES:000022 ! embryo xref: EV:0300001 ! embryo xref: OGES:000000 ! Embryo is_a: UBERON:0000105 ! life cycle stage relationship: simultaneous_with GO:0009790 relationship: part_of UBERON:0000104 ! life cycle xref: SCTID:296280003 ! Entire embryo stage xref: BilaDO:0000002 ! embryo xref: MmusDv:0000002 ! embryo xref: HsapDv:0000002 ! embryonic stage [Term] id: UBERON:0007220 ! late embryonic stage name: late embryonic stage synonym: "fetus" NARROW [MIAA:0000399] synonym: "fetal stage" NARROW SENSU [UBERON:cjm] synonym: "fetus stage" NARROW SENSU [UBERON:cjm] synonym: "embryo late (growth) stage" EXACT [MIAA:0000399] synonym: "embryo late growth stage" RELATED [BTO:0000449] synonym: "embryo late stage" RELATED [BTO:0000449] xref: EVM:2990031 xref: MIAA:0000399 ! embryo late (growth) stage xref: OGES:000023 ! fetus xref: EV:0300011 ! fetus xref: FBdv:00005333 ! late embryonic stage xref: MmusDv:0000031 ! fetus is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: has_end UBERON:0000103 ! life cycle stage boundary xref: SCTID:367619004 ! Entire late embryo stage [Term] id: UBERON:0000069 name: larval stage def: "a distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva] comment: It is a misunderstanding that the larval form always reflects the group's evolutionary history. It could be the case, but often the larval stage has evolved secondarily, as in insects. In these cases the larval form might differ more from the group's common origin than the adult form[WP]. Uberon includes clade-specific subclasses. synonym: "larva stage" EXACT [] synonym: "larva" RELATED [] synonym: "tornaria" NARROW SENSU [NCBITaxon:10219] synonym: "metacestode" NARROW SENSU [BTO:0000859] synonym: "planula" NARROW SENSU [Wikipedia:Larva] synonym: "nauplius" NARROW SENSU [Wikipedia:Larva] synonym: "zoea" NARROW SENSU [Wikipedia:Larva] synonym: "nymph" NARROW SENSU [Wikipedia:Larva] synonym: "naiad, nymph" NARROW SENSU [Wikipedia:Larva] synonym: "caterpillar" NARROW SENSU [Wikipedia:Larva] synonym: "grub" NARROW SENSU [Wikipedia:Larva] synonym: "maggot" NARROW SENSU [Wikipedia:Larva] synonym: "wriggler" NARROW SENSU [Wikipedia:Larva] synonym: "trochophore" NARROW SENSU [Wikipedia:Larva] synonym: "veliger" NARROW SENSU [Wikipedia:Larva] synonym: "glochidium" NARROW SENSU [Wikipedia:Larva] synonym: "ammocoete" NARROW SENSU [Wikipedia:Larva] synonym: "leptocephalus" NARROW SENSU [Wikipedia:Larva] synonym: "bipinnaria" NARROW SENSU [Wikipedia:Larva] synonym: "planula stage" NARROW SENSU [Wikipedia:Larva] synonym: "nauplius stage" NARROW SENSU [Wikipedia:Larva] synonym: "zoea stage" NARROW SENSU [Wikipedia:Larva] synonym: "nymph stage" NARROW SENSU [Wikipedia:Larva] synonym: "naiad, nymph stage" NARROW SENSU [Wikipedia:Larva] synonym: "caterpillar stage" NARROW SENSU [Wikipedia:Larva] synonym: "grub stage" NARROW SENSU [Wikipedia:Larva] synonym: "maggot stage" NARROW SENSU [Wikipedia:Larva] synonym: "wriggler stage" NARROW SENSU [Wikipedia:Larva] synonym: "trochophore stage" NARROW SENSU [Wikipedia:Larva] synonym: "veliger stage" NARROW SENSU [Wikipedia:Larva] synonym: "glochidium stage" NARROW SENSU [Wikipedia:Larva] synonym: "ammocoete stage" NARROW SENSU [Wikipedia:Larva] synonym: "leptocephalus stage" NARROW SENSU [Wikipedia:Larva] synonym: "bipinnaria stage" NARROW SENSU [Wikipedia:Larva] xref: EFO:0001303 ! larval stage xref: BTO:0000915 ! nauplius xref: BTO:0000954 ! nymph xref: OGES:000008 xref: MIAA:0000400 ! larval stage xref: FBdv:00005336 ! larval stage xref: ZFS:0000048 ! larva is_a: UBERON:0000092 ! post-embryonic stage relationship: simultaneous_with GO:0002164 relationship: immediately_preceded_by UBERON:0000068 ! embryo stage relationship: never_in_taxon NCBITaxon:32524 ! Amniota [Term] id: UBERON:0004728 name: amphibian larval stage def: "Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form." [GO:0002117] comment: AO notes: the XAO class denotes a stage synonym: "tadpole stage" NARROW SENSU [Wikipedia:Larva] synonym: "polliwog stage" NARROW SENSU [Wikipedia:Larva] synonym: "tadpole" NARROW SENSU [Wikipedia:Larva] synonym: "polliwog" NARROW SENSU [Wikipedia:Larva] synonym: "larva" RELATED [XAO:1000008] synonym: "larva stage" BROAD [] xref: XAO:1000008 ! tadpole stage xref: XtroDO:0000056 ! tadpole is_a: UBERON:0000069 ! larval stage relationship: simultaneous_with GO:0002117 ! amphibian larval development relationship: only_in_taxon NCBITaxon:8292 ! Amphibia [Term] id: UBERON:0004729 ! nematode larval stage name: nematode larval stage def: "Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GO:0002119] xref: WBls:0000023 ! larva is_a: UBERON:0000069 ! larval stage relationship: simultaneous_with GO:0002119 ! nematode larval development relationship: only_in_taxon NCBITaxon:6231 ! Nematoda [Term] id: UBERON:0009850 ! nematode larva name: nematode larva is_a: UBERON:0002548 ! larva intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0004729 ! nematode larval stage def: "A multi-cellular organism that existence_starts_and_ends_during a nematode larval stage." [OBOL:automatic] [Term] id: UBERON:0004730 name: instar larval stage def: "This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster." [GO:0002168] xref: FBdv:00005336 is_a: UBERON:0000069 ! larval stage relationship: simultaneous_with GO:0002168 ! instar larval development [Term] id: UBERON:0008264 name: echinopluteus larval stage def: "Larval stage in echinoderms characterized by a planktonic and feeding larval form that possesses limb-like outgrowths bearing ciliated bands." [http://www.encyclopedia.com/doc/1O8-echinopluteuslarva.html] synonym: "pluteus larval stage" EXACT [] is_a: UBERON:0000069 ! larval stage relationship: only_in_taxon NCBITaxon:7586 ! Echinodermata [Term] id: UBERON:0000070 name: pupal stage def: "A life stage of some insects undergoing transformation. The pupal stage is found only in holometabolous insects, those that undergo a complete metamorphosis, going through four life stages; embryo, larva, pupa and imago." [Wikipedia:Pupa] synonym: "pupa stage" EXACT [] synonym: "aurelia stage" NARROW [Wikipedia:Pupa, NCBITaxon:37572] synonym: "chrysalis stage" NARROW [Wikipedia:Pupa, NCBITaxon:37572] synonym: "chrysalides stage" NARROW [Wikipedia:Pupa, NCBITaxon:37572] xref: FBdv:00005349 is_a: UBERON:0000092 ! post-embryonic stage relationship: simultaneous_with GO:0035209 relationship: immediately_preceded_by UBERON:0000069 ! larval stage relationship: only_in_taxon NCBITaxon:33392 ! Endopterygota [Term] id: UBERON:0000092 name: post-embryonic stage def: "stage succeeding embryo, including mature structure" [UBERON:cjm] comment: In birds, the postnatal stage begins when the beak penetrates the shell (i.e., external pipping) (Brown et al. 1997) synonym: "postembryonic stage" EXACT [] synonym: "postembryonic" RELATED [] synonym: "post-hatching stage" NARROW [] xref: WBls:0000022 ! postembryonic xref: OGES:000010 xref: OGES:000024 xref: OGES:000014 xref: BilaDO:0000003 ! post-embryonic development xref: MmusDv:0000030 ! post-embryonic development is_a: UBERON:0000105 ! life cycle stage disjoint_from: UBERON:0000068 ! embryo stage relationship: part_of UBERON:0000104 ! life cycle relationship: simultaneous_with GO:0009791 relationship: preceded_by UBERON:0000068 ! embryo stage [Term] id: UBERON:0012101 name: perinatal stage def: "the period spanning the range immediately before and after birth" [] comment: In birds, the paranatal stage starts when the beak penetrates into the air pocket (air cell) between the inner and outer shell membranes synonym: "paranatal stage" NARROW [] is_a: UBERON:0000105 ! life cycle stage relationship: overlaps UBERON:0000092 ! post-embryonic stage relationship: overlaps UBERON:0000068 ! embryo stage [Term] id: UBERON:0000071 name: death stage def: "End of the life of an organism." [XAO:0000437] comment: AO notes - ncit:Death is an outcome synonym: "death" RELATED [] xref: XAO:0000437 ! death xref: XtroDO:0000085 ! death is_a: UBERON:0000105 ! life cycle stage relationship: simultaneous_with GO:0016265 relationship: finishes UBERON:0000104 ! life cycle relationship: part_of UBERON:0000104 ! life cycle [Term] id: UBERON:0000072 name: segment of respiratory tract def: "An organ segment that is part of a respiratory tract [Automatically generated definition]." [OBOL:automatic] comment: Note that MA:0000434 has subclasses upper and lower, so it corresponds to a segment of the tract, rather than the tract as a whole synonym: "respiratory tract" RELATED [MA:0000434] xref: MA:0000434 ! respiratory tract intersection_of: UBERON:0000063 ! organ segment intersection_of: part_of UBERON:0000065 ! respiratory tract [Term] id: UBERON:0000063 name: organ segment def: "Organ region with one or more fixed or anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball[FMA]." [FMA:86140] synonym: "organ region with fixed fiat boundary" EXACT [FMA:86140] synonym: "segment of organ" EXACT [FMA:86140] subset: upper_level xref: FMA:86140 ! Organ segment is_a: UBERON:0000064 ! organ part [Term] id: UBERON:0000914 ! organismal segment name: organismal segment def: "One of the repeated divisions of the whole organism." [FB:gg, Wikipedia:Segmentation_(biology)] comment: editor note: review this post-CARO2 subset: uberon_slim subset: upper_level xref: FBbt:00000003 ! segment synonym: "segment" EXACT [FBbt:00000003] xref: HAO:0000929 ! segment xref: MAT:0000271 ! segment - adult xref: MIAA:0000271 ! segment - adult is_a: UBERON:0000475 ! organism subdivision [Term] id: UBERON:0008834 name: prostomium def: "The first body segment in annelids worms. It is in front of (but does not include) the mouth, being usually a small shelf- or lip-like extension over the dorsal side of the mouth. It sometimes bears antennae and eyes. By feeding, it often functions like a kind of overlip. The shape and composition of prostomium are important for annelid systematics." [Wikipedia:Prostomium] synonym: "acron" RELATED [BTO:0004198] is_a: UBERON:0000914 ! organismal segment xref: BTO:0004198 ! prostomium relationship: only_in_taxon NCBITaxon:6340 {source="Wikipedia"} ! Annelida [Term] id: UBERON:0008880 name: annelid pygidium def: "Rearmost segment of annelid worms." [Wikipedia:Annelid#Segmentation] is_a: UBERON:0000914 ! organismal segment relationship: only_in_taxon NCBITaxon:6340 {source="Wikipedia"} ! Annelida [Term] id: UBERON:0000073 name: regional part of nervous system def: "An anatomical structure that is part of a nervous system [Automatically generated definition]." [OBOL:automatic] subset: upper_level subset: non_informative synonym: "part of nervous system" EXACT [NIF_GrossAnatomy:birnlex_1157] xref: NIF_GrossAnatomy:birnlex_1157 ! Part of nervous system intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001016 ! nervous system created_by: Melissa Haendel creation_date: 2009-06-18T09:00:04Z xref: ncithesaurus:Nervous_System_Part ! Nervous System Part xref: SCTID:25087005 ! Structure of nervous system xref: UMLS:C1518256 [Term] id: UBERON:0004732 ! segmental subdivision of nervous system name: segmental subdivision of nervous system def: "An organ segment that is part of a nervous system [Automatically generated definition]." [OBOL:automatic] comment: Editor note: revisit this after CARO is revised and/or we have defined metameric segment synonym: "neuromere" RELATED [FBbt:00005140] xref: FBbt:00005140 ! neuromere intersection_of: UBERON:0000063 ! organ segment intersection_of: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0004733 ! segmental subdivision of hindbrain name: segmental subdivision of hindbrain def: "An organ segment that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] synonym: "hindbrain segment" EXACT [FMA:61998] synonym: "segment of hindbrain" EXACT [FMA:61998] xref: FMA:61998 ! Segment of hindbrain intersection_of: UBERON:0000063 ! organ segment intersection_of: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0004731 ! neuromere name: neuromere def: "A segment of the developing neural tube[MP]. A metameric segment of the central nervous system[ZFA]. morphologically or molecularly defined transient segments of the early developing brain. Rhombomeres are such segments that make up the rhombencephalon or hindbrain. [WP]." [Wikipedia:Neuromere, MP:0003208] comment: WP says: "More controversially, some argue that there exist early developmental segments that give rise to structures of the midbrain (mesomeres) and forebrain (prosomeres).". Note that ZFA has spinal neuromere synonym: "neural segment" EXACT [] synonym: "neural tube segment" EXACT [] synonym: "neuromere" EXACT [] xref: TAO:0001328 ! neuromere xref: ZFA:0001328 ! neuromere intersection_of: UBERON:0004732 ! segmental subdivision of nervous system intersection_of: part_of UBERON:0001049 ! neural tube created_by: Melissa Haendel creation_date: 2009-06-18T09:00:04Z property_value: external_definition "A metameric segment of the central nervous system.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001328", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "neuromeres" EXACT PLURAL [TAO:0001328] [Term] id: UBERON:0001892 ! rhombomere name: rhombomere def: "A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure. In human embryonic development, the rhombomeres are present by day 29[WP]." [Wikipedia:Rhombomere, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "future rhombencephalon" RELATED [MIAA:0000272] synonym: "hindbrain segment" BROAD [ZFA:0001064] synonym: "rhombomere" EXACT [] synonym: "segment of hindbrain" BROAD [ZFA:0001064] xref: VHOG:0000672 ! rhombomere xref: MAT:0000272 ! rhombomere xref: MIAA:0000272 ! rhombomere xref: TAO:0001064 ! rhombomere xref: ZFA:0001064 ! rhombomere xref: RETIRED_EHDAA2:0000669 ! future rhombencephalon xref: EMAPA:16148 ! future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16478 ! future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EFO:0003617 ! rhombomere intersection_of: UBERON:0004731 ! neuromere intersection_of: part_of UBERON:0002028 ! hindbrain xref: XAO:0004079 ! rhombomere property_value: external_definition "A segment of the developing hindbrain. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001064", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "rhombomeres" RELATED PLURAL [VHOG:0000672] property_value: homology_notes "Rhombomeric segmentation is found in all living vertebrates and is of fundamental importance to the development of the vertebrate head.[well established][VHOG]" xsd:string {external_class="VHOG:0000672", ontology="VHOG", source="DOI:10.1006/dbio.2002.0831 Mazet F\, Shimeld SM\, The Evolution of Chordate Neural Segmentation. Developmental Biology (2002)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000074 ! renal glomerulus name: renal glomerulus def: "A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]." [MP:0005325, Wikipedia:Glomerulus] comment: ZFA - The multi-tissue structure where the glomerular basement membrane supported by mesonephric podocytes filters blood from the glomerular capillaries. TODO - split glomerulus and glomerular tuft? DONE. GUDMAP: 'Together, the Bowman’s capsule and the glomerulus comprise the definitive renal corpuscle.' - here the glomerulus is part of the capsule? subset: vertebrate_core synonym: "glomerulus" BROAD [] synonym: "glomerular tuft" RELATED INCONSISTENT [] synonym: "renal corpuscle" RELATED INCONSISTENT [] synonym: "glomerular capillary tuft" RELATED [ZFA:0001288] synonym: "malphigian glomerulus" RELATED [BTO:0000530] xref: FMA:15624 ! Glomerulus xref: MA:0001657 ! glomerulus xref: ZFA:0001288 ! renal glomerulus xref: BTO:0000530 ! renal glomerulus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray1130.svg/200px-Gray1130.svg.png xref: http://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg xref: MESH:A05.810.453.736.520 ! kidney glomerulus xref: EV:0100386 ! glomerus xref: EFO:0003667 ! renal glomerulus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001229 {source="MA"} ! renal corpuscle relationship: surrounded_by UBERON:0001230 ! glomerular capsule relationship: develops_from UBERON:0005749 ! glomerular tuft created_by: Melissa Haendel creation_date: 2009-06-18T09:26:37Z xref: ncithesaurus:Glomerulus ! Glomerulus xref: TAO:0001288 ! renal glomeruli synonym: "glomerulus renis" RELATED LATIN [Wikipedia:Glomerulus] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg xref: SCTID:362217000 ! Entire glomerulus synonym: "renal glomeruli" EXACT [TAO:0001288] xref: UMLS:C0022663 [Term] id: UBERON:0005749 ! glomerular tuft name: glomerular tuft def: "the capillary loops of the kidney that normally function as a filtration unit[MP]. ...Soon afterwards, endothelial cells invade to make a capillary knot-like outgrowth, the glomerular tuft, which goes on to form the glomerulus[GudMap]." [MP:0005325, Wikipedia:Glomerulus, http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "glomerulus" RELATED INCONSISTENT [EMAPA:28239] synonym: "glomerular capillary tuft" RELATED [] xref: EMAPA:28239 ! glomerular tuft is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001230 ! glomerular capsule relationship: has_function_in GO:0003094 ! glomerular filtration relationship: develops_from UBERON:0003220 {source="Wikipedia"} ! metanephric mesenchyme xref: SCTID:362217000 ! Entire glomerulus [Term] id: UBERON:0004736 name: metanephric glomerulus def: "glomerulus of the mature vertebrate kidney, or metanephros." [GO:0072224] synonym: "glomerulus of metanephros" EXACT [] xref: VHOG:0001242 ! metanephric glomerulus intersection_of: UBERON:0000074 ! renal glomerulus intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0000077 name: mixed endoderm/mesoderm-derived structure def: "An anatomical structure that develops from the endoderm and the mesoderm." [UBERON:cjm] comment: Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple subset: grouping_class is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: develops_from UBERON:0000926 ! mesoderm [Term] id: UBERON:0000078 name: mixed ectoderm/mesoderm/endoderm-derived structure def: "An anatomical structure that develops from the ectoderm, mesoderm and endoderm." [UBERON:cjm] comment: Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple subset: grouping_class is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000924 ! ectoderm intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: develops_from UBERON:0000926 ! mesoderm [Term] id: UBERON:0004119 name: endoderm-derived structure def: "An anatomical structure that develops (entirely or partially) from the endoderm." [UBERON:cjm] comment: Grouping term for query purposes subset: grouping_class is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000925 ! endoderm [Term] id: UBERON:0004120 ! mesoderm-derived structure name: mesoderm-derived structure def: "An anatomical structure that develops (entirely or partially) from the mesoderm." [UBERON:cjm] comment: Grouping term for query purposes subset: grouping_class is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000926 ! mesoderm [Term] id: UBERON:0004121 name: ectoderm-derived structure def: "An anatomical structure that develops (entirely or partially) from the ectoderm." [UBERON:cjm] comment: Grouping term for query purposes subset: grouping_class is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000924 ! ectoderm [Term] id: UBERON:0010313 name: neural crest-derived structure def: "An anatomical structure that develops from the neural crest." [UBERON:cjm] comment: Grouping term for query purposes subset: grouping_class ! Subset consisting of classes creating for grouping purposes intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0002342 ! neural crest [Term] id: UBERON:0010314 name: structure with developmental contribution from neural crest def: "An anatomical structure that has some part that develops from the neural crest." [UBERON:cjm] comment: Grouping term for query purposes subset: grouping_class ! Subset consisting of classes creating for grouping purposes intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_developmental_contribution_from UBERON:0002342 ! neural crest [Term] id: UBERON:0010317 name: obsolete germ layer / neural crest derived structure comment: Grouping term for query purposes is_obsolete: true [Term] id: UBERON:0000079 name: male reproductive system def: "the organs associated with producing offspring in the gender that produces spermatozoa." [MP:0001145] synonym: "male genital system" EXACT [FMA:45664] synonym: "male genitals" EXACT [] synonym: "male genitalia" EXACT [] synonym: "genitalia of male organism" EXACT [OBOL:automatic] synonym: "male organism genitalia" EXACT [OBOL:automatic] synonym: "male organism reproductive system" EXACT [OBOL:automatic] synonym: "reproductive system of male organism" EXACT [OBOL:automatic] synonym: "male reproductive tract" RELATED [MA:0000396] synonym: "male genital organ" RELATED [BTO:0000082] synonym: "systema genitale masculinum" RELATED [BTO:0000082] xref: BTO:0000082 xref: FBbt:00004927 ! male reproductive system xref: HAO:0000505 ! male genitalia xref: VHOG:0000725 ! male reproductive system xref: OpenCyc:Mx4rvViCepwpEbGdrcN5Y29ycA xref: GAID:386 ! male genitalia xref: OpenCyc:Mx4rvViCepwpEbGdrcN5Y29ycA ! male reproductive system xref: FMA:45664 ! Male genital system xref: EHDAA2:0001054 ! male reproductive system xref: MA:0000396 ! male reproductive system xref: ncithesaurus:Male_Reproductive_System ! Male Reproductive System xref: ncithesaurus:Male_Genitalia ! male genitalia xref: EFO:0000970 ! male reproductive system xref: XAO:0000155 ! male genitalia xref: TGMA:0000634 ! male genitalia xref: EMAPA:17968 ! male reproductive system xref: MESH:A05.360.444 ! male genitalia xref: EHDAA:8136 ! male xref: EV:0100101 ! male reproductive system xref: WBbt:0008423 ! male genital is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003101 ! male organism disjoint_from: UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0003101 ! male organism xref: SCTID:361340001 ! Entire male genital system property_value: homology_notes "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000725", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J\, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0017422 xref: UMLS:C1963704 [Term] id: UBERON:0000080 name: mesonephros def: "In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney[GO]. One of three excretory organs that develop in vertebrates. It serves as the main excretory organ of aquatic vertebrates and as a temporary kidney in higher vertebrates. composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, Wikipedia:Mesonephros] comment: By contrast to the pronephros, the histological features of the mesonephros, with its primitive glomeruli, suggest that it probably functions as a primitive kidney, and is involved in the production of much of the amniotic fluid. Within the two mesonephroi, one located on either side of the dorsal mesentery of the hindgut, a substantial number (in the region of about 40 or more) of cranio-caudally segmented mesonephric tubules are formed. It has, however, been suggested that only the most rostrally located 4-6 pairs of mesonephric tubules drain into the mesonephric portion of the nephric duct. This is now seen to extend along the length of the mesonephroi, being located towards their lateral sides. The mesonephros is also retained over a considerably longer period than the pronephros, but gradually undergoes regression in a cranio-caudal direction. While the rostral part displays clear evidence of regression its more caudal part appears to display evidence of functional activity. Within the medial part of the mesonephros, vesicles are formed, although no glomeruli are formed there in this species. It is, however, difficult to believe that the relatively enormous mesonephroi do not have an excretory role in the mouse, only serving as a base for gonadal differentiation. In the human embryo, the medial part of the mesonephric tubules enlarges, become invaginated by capillaries, and form glomeruli. These then take on an excretory role. In the mouse, the mesonephric ducts appear to be patent throughout their length[GUDMAP] comment: Taxon notes: The mesonephros persists and form the permanent kidneys in fishes and amphibians, but in reptiles, birds, and mammals, it atrophies and for the most part disappears rapidly as the permanent kidney (metanephros) begins to develop during the sixth or seventh week. By the beginning of the fifth month only the ducts and a few of the tubules of the mesonephros remain[WP] subset: vertebrate_core synonym: "mesonephroi" EXACT PLURAL [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "opisthonephros" RELATED [XAO:0000141, VHOG:0000038] synonym: "opistonephros" RELATED [http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html] synonym: "opisto nephros" RELATED [] synonym: "Wolffian body" EXACT [BTO:0001542, GOC:yaf, MESH:A16.254.500, Wikipedia:Mesonephros] synonym: "mesonephric kidney" EXACT [XAO:0000141] xref: EFO:0000928 ! mesonephros xref: FMA:72171 ! Mesonephros xref: VHOG:0000038 ! mesonephros xref: ZFA:0000529 ! kidney xref: TAO:0000529 ! kidney xref: ncithesaurus:Mesonephros ! Mesonephros xref: GAID:1308 ! mesonephros xref: EHDAA:1581 ! mesonephros xref: EHDAA:5903 ! mesonephros xref: EHDAA2:0001130 ! mesonephros xref: XAO:0000141 ! mesonephric kidney xref: AAO:0010384 ! mesonephric kidney xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ad/Gray986.png/200px-Gray986.png xref: BTO:0001542 ! mesonephron xref: EMAPA:17369 ! mesonephros xref: EMAPA:16744 ! mesonephros of genitourinary system xref: EMAPA:27644 ! mesonephros of reproductive system xref: MESH:A16.254.500 ! mesonephros is_a: UBERON:0002113 ! kidney relationship: develops_from UBERON:0002120 ! pronephros xref: SCTID:308799002 ! Entire mesonephros subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray986.png property_value: external_definition "Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010384", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "A kidney formed of nephric tubules arising in the middle region of the nephric ridge; a transient embryonic stage that replaces the pronephros, but is itself replaced by the adult metanephros [in mammals; in fishes and amphibians it is the adult kidney]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000038", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates. (...) In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {external_class="VHOG:0000038", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "mesonephric" xsd:string xref: UMLS:C0025492 [Term] id: UBERON:0000081 ! metanephros name: metanephros def: "In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO]. During the fifth week of gestation, the mesonephric duct develops an outpouching, the ureteric bud, near its attachment to the cloaca. This bud, also called the metanephrogenic diverticulum, grows posteriorly and towards the head of the embryo. The elongated stalk of the ureteric bud, the metanephric duct, later forms the ureter. As the cranial end of the bud extends into the intermediate mesoderm, it undergoes a series of branchings to form the collecting duct system of the kidney. It also forms the major and minor calyces and the renal pelvis." [GO:0001656, Wikipedia:Metanephros#Metanephros] comment: TODO check developmental relationships synonym: "metanephron" EXACT [BTO:0001543] synonym: "definite kidney" RELATED [BTO:0001543] synonym: "definitive kidney" RELATED [BTO:0001543] synonym: "hind kidney" RELATED [BTO:0001543] xref: FMA:72172 ! Metanephros xref: VHOG:0000039 ! metanephros xref: BTO:0001543 ! metanephron xref: ncithesaurus:Metanephros ! Metanephros xref: EHDAA:3089 ! metanephros xref: EHDAA:5911 ! metanephros xref: EHDAA2:0001137 ! metanephros xref: EMAPA:17207 ! metanephros of genitourinary system xref: EMAPA:17373 ! metanephros of urinary system is_a: UBERON:0002113 ! kidney relationship: developmentally_replaces UBERON:0000080 {source="ISBN:9780878932504"} ! mesonephros relationship: develops_from UBERON:0005753 ! caudal part of nephrogenic cord relationship: develops_from UBERON:0005080 {source="GO"} ! metanephric ureteric bud xref: SCTID:308797000 ! Entire metanephros subset: organ_slim relationship: develops_from UBERON:0003220 {evidence="definitional"} ! metanephric mesenchyme synonym: "metanephric kidney" RELATED [VHOG:0000039] property_value: external_definition "A kidney formed of nephric tubules arising in the posterior region of the nephric ridge and drained by a ureter; replaces the embryonic pronephros and mesonephros [in mammals]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000039", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {external_class="VHOG:0000039", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.543", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "metanephric" xsd:string xref: UMLS:C0231049 [Term] id: UBERON:0000084 name: ureteric bud def: "a protrusion from the mesonephric duct during the development of the urinary and reproductive organs. It later develops into the adult kidney, except for the nephrons, which, in contrast, originate from the metanephric blastema[WP]. epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]" [Wikipedia:Ureteric_bud, MP:0010979, PMID:19828308, https://sourceforge.net/tracker/?group_id=36855&atid=440764] synonym: "metanephric diverticulum" RELATED [Wikipedia:Metanephros#Metanephros] synonym: "diverticulum" RELATED [BTO:0001646] synonym: "metanephric bud" RELATED [BTO:0001646] synonym: "ureteric ampulla" RELATED [] synonym: "gemma ureterica" RELATED LATIN [Wikipedia:Ureteric_bud] synonym: "diverticulum metanephricum" RELATED LATIN [Wikipedia:Ureteric_bud] synonym: "ureteric diverticulum" RELATED [VHOG:0000541] xref: VHOG:0000541 ! ureteric bud xref: BTO:0001646 ! ureteric bud xref: EHDAA:3091 ! ureteric bud xref: EHDAA:5917 ! ureteric bud xref: EHDAA2:0002140 ! ureteric bud xref: EMAPA:17209 ! ureteric bud of metanephros of genitourinary system xref: EMAPA:17376 ! ureteric bud of metanephros of urinary system is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: part_of UBERON:0003074 ! mesonephric duct relationship: develops_from UBERON:0003074 {source="EHDAA2"} ! mesonephric duct relationship: induced_by UBERON:0003220 {source="ISBN:9780878932504"} ! metanephric mesenchyme xref: ncithesaurus:Metanephric_Diverticulum ! Metanephric Diverticulum xref: SCTID:361528000 ! Ureteric bud property_value: external_definition "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000541", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {external_class="VHOG:0000541", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.543", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1284058 [Term] id: UBERON:0006364 name: ureteric bud tip def: "The terminal end of the ureteric tree; the ureteric tip cells are proliferating immature cells located at the branching points that induce the adjacent cap mesenchyme to undergo nephrogenesis." [http://www.gudmap.org/Organ_Summaries/Metanephros/Ureteric_tip.html, MP:0011760] comment: Editor note: MA placement to be checked synonym: "ureteric bud ampulla" RELATED [MP:0011760] synonym: "ureteric ampulla" RELATED [MP:0011760] xref: MA:0002601 ! ureteric tip xref: EMAPA:27605 ! ureteric tip of ureteric bud of metanephros of genitourinary system xref: EMAPA:27625 ! ureteric tip of ureteric bud of metanephros of urinary system xref: EMAPA:27694 ! ureteric tip of primitive collecting duct xref: EMAPA:27749 ! ureteric tip of collecting duct is_a: UBERON:0007499 ! epithelial sac relationship: part_of UBERON:0000084 ! ureteric bud xref: http://www.gudmap.org/Images/Organ_Summaries/Metanephros/Slide10.png [Term] id: UBERON:0012238 name: ureteric bud trunk def: "ureteric bud cells that elongate to form a rigid structure (stalk) consisting of polarized epithelial cells without branching; the stalks differentiate into the collecting system of the mature kidney, while the tip cells interact with the adjacent cells of the metanephric mesenchyme, inducing their conversion into nephrons." [MP:0011761] synonym: "ureteric stalk" RELATED [EMAPA:27608] synonym: "ureteric trunk" RELATED [EMAPA:27608] synonym: "ureteric bud stalk" RELATED [MP:0011761] is_a: UBERON:0010137 ! polarized epithelium relationship: part_of UBERON:0000084 ! ureteric bud xref: EMAPA:27608 ! ureteric trunk xref: EMAPA:27627 ! ureteric stalk xref: EMAPA:27697 ! ureteric trunk xref: EMAPA:28405 ! ureteric trunk xref: EMAPA:28494 ! ureteric trunk [Term] id: UBERON:0005080 ! metanephric ureteric bud name: metanephric ureteric bud def: "the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]." [GO:0035502, https://sourceforge.net/tracker/?group_id=36855&atid=440764] intersection_of: UBERON:0000084 ! ureteric bud intersection_of: develops_into UBERON:0000081 ! metanephros [Term] id: UBERON:0005081 ! ureter ureteric bud name: ureter ureteric bud def: "The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]." [GO:0035503] intersection_of: UBERON:0000084 ! ureteric bud intersection_of: develops_into UBERON:0000056 ! ureter [Term] id: UBERON:0000082 name: adult mammalian kidney is_a: UBERON:0002113 ! kidney relationship: develops_from UBERON:0000081 ! metanephros relationship: develops_from UBERON:0000084 ! ureteric bud [Term] id: UBERON:0005760 name: urorectal septum def: "The ridge of mesoderm covered with endoderm that in the early developing embryo partitions the endodermal cloaca into the primary urogenital sinus (ventrally) and the anorectal canal of the hindgut (dorsally); the urorectal septum eventually fuses with the cloacal membrane, dividing it into a dorsal anal membrane and a larger ventral urogenital membrane - this area of fusion is represented in the adult by the perineal body[MP]." [Wikipedia:Urorectal_septum, MP:anna] comment: Editor notes: todo - use to define cloacal septation in GO synonym: "urorectal fold" EXACT [MP:anna] synonym: "urorectal membrane" EXACT [MP:anna] synonym: "cloacal septum" RELATED [VHOG:0000018] synonym: "septum urorectale" EXACT LATIN [Wikipedia:Urorectal_septum] xref: Wikipedia:Urorectal_septum ! urorectal septum xref: VHOG:0000018 ! urorectal septum xref: EMAPA:17380 ! urorectal septum of urinary system xref: EMAPA:17212 ! urorectal septum of genitourinary system xref: EHDAA:5921 ! urorectal septum xref: EHDAA2:0002152 ! urorectal septum is_a: UBERON:0003037 ! septum relationship: part_of UBERON:0001008 ! urinary system relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region xref: ncithesaurus:Urorectal_Septum ! Urorectal Septum xref: http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray992.png property_value: external_definition "A ridge of mesoderm covered with endoderm that in the early developing embryo divides the endodermal cloaca into the urogenital sinus and the rectum. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000018", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/urorectal+septum", source="http://bgee.unil.ch/"} property_value: homology_notes "In mammals the lowly monotremes still have a cloaca. Higher types have done away with this structure and have a separate anal outlet for the rectum. The monotreme cloaca shows the initiation of this subdivision. The cloaca has such includes only the distal part, roughly comparable to the proctodeum. The more proximal part is divided into (1) a large dorsal passage into which the intestine opens, the coprodeum, and (2) a ventral portion, the urodeum with which the bladder connects. (...) the development of the placental mammals recapitulates in many respects the phylogenetic story. In the sexually indifferent stage of placental mammal there is a cloaca. While the indifferent stage still persists, a septum develops, and extends out to the closing membrane. This divides the cloaca into two chambers: a coprodeum continuous with the gut above, and a urodeum or urogenital sinus below.[well established][VHOG]" xsd:string {external_class="VHOG:0000018", ontology="VHOG", source="ISBN:978-0721676678 Romer AS\, Vertebrate body (1970) p.388-89 and Figure 300", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1519838 [Term] id: UBERON:0000083 name: mesonephric tubule def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] comment: TODO check xref: VHOG:0000500 ! mesonephric tubule xref: XAO:0000148 ! mesonephric tubule xref: EMAPA:27588 ! mesonephric tubule of mesonephros of genitourinary system xref: EMAPA:27659 ! mesonephric tubule of mesonephros of reproductive system xref: EHDAA2:0001134 ! mesonephros tubule intersection_of: UBERON:0003914 ! epithelial tube intersection_of: part_of UBERON:0000080 ! mesonephros xref: AAO:0010389 ! mesonephric tubule synonym: "tubuli mesonephrici" RELATED LATIN [Wikipedia:Mesonephric_tubules] synonym: "renal tubules" RELATED PLURAL [VHOG:0000500] property_value: external_definition "Any of the renal tubules composing the mesonephros. In mammals they function as excretory structures during the early embryonic development but are later incorporated into the reproductive system. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000500", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/mesonephric+tubule", source="http://bgee.unil.ch/"} property_value: homology_notes "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000500", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000086 name: zona pellucida def: "A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes." [Wikipedia:Zona_pellucida] subset: vertebrate_core synonym: "vitelline membrane" RELATED [] synonym: "vitelline envelope" RELATED [] synonym: "oolemma" RELATED [BTO:0003135] synonym: "pellucid zone" RELATED [BTO:0003135] synonym: "striated membrane" RELATED [BTO:0003135] synonym: "zona radiata" RELATED [BTO:0003135] synonym: "zona striata" RELATED [BTO:0003135] xref: EHDAA:31 ! zona pellucida xref: EHDAA:62 ! zona pellucida xref: GAID:410 ! zona pellucida xref: MA:0001715 ! zona pellucida xref: FMA:18674 ! Zona pellucida xref: ncithesaurus:Zona_Pellucida ! Zona Pellucida xref: BTO:0003135 ! zona pellucida xref: EHDAA2:0002220 ! zona pellucida xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/81/Gray3.png/200px-Gray3.png xref: EMAPA:16035 ! zona pellucida of mouse xref: EMAPA:16049 ! zona pellucida of extraembryonic component xref: MESH:A05.360.490.690.950 ! zona pellucida xref: ZFA:0001111 ! zona radiata xref: VHOG:0000720 ! zona pellucida - vitelline membrane (also: UBERON:0003125 'vitelline membrane') is_a: UBERON:0000476 ! acellular anatomical structure relationship: surrounds CL:0000023 ! oocyte relationship: part_of UBERON:0000992 ! female gonad xref: TAO:0001111 ! zona radiata xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Gray3.png synonym: "zona pellucida - vitelline membrane" BROAD [VHOG:0000720] property_value: homology_notes "Outside the plasma membrane, three envelopes surround the ovum. The first, the primary egg envelope, lies between the plasma membrane and the surrounding cells of the ovary. The most consistent component of this primary layer is the vitelline membrane, a transparent jacket of fibrous protein. In mammals, the homologous structure is called the zona pellucida.[well established][VHOG]" xsd:string {external_class="VHOG:0000720", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.159", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0043519 [Term] id: UBERON:0005764 name: acellular membrane xref: FMA:63871 ! Acellular membrane is_a: UBERON:0000476 ! acellular anatomical structure [Term] id: UBERON:0005769 name: basement membrane comment: we include this even though it is redundant with GO because we have subclasses that are appropriate for an ontology of gross anatomy synonym: "Basement membrane of connective tissue" EXACT [FMA:63872] synonym: "basal lamina" RELATED [GAID:915] synonym: "basement lamina" RELATED [GAID:915] xref: FMA:63872 ! Basement membrane xref: GAID:915 ! basement membrane xref: GO:0005604 ! basement membrane is_a: UBERON:0005764 ! acellular membrane relationship: part_of UBERON:0000483 ! epithelium xref: ncithesaurus:Basement_Membrane ! Basement Membrane xref: AAO:0010596 ! basement membrane xref: SCTID:68989006 ! Basement membrane xref: UMLS:C0004799 [Term] id: UBERON:0004749 name: blastodisc def: "a small, circular, white spot (approximately 2-3 mm across) on the surface of the yellow yolk of an egg that has been laid. The nucleus of the egg is in the germinal disc." [Wikipedia:Germinal_disc] synonym: "germinal disc" EXACT [Wikipedia:Germinal_disc] xref: AAO:0000043 ! blastodisc xref: ZFA:0001175 ! blastodisc xref: BTO:0000494 ! germinal disc xref: BTO:0001504 ! blastodisc is_a: UBERON:0002050 ! embryonic structure xref: TAO:0001175 ! blastodisc [Term] id: UBERON:0004750 name: blastoderm def: "A layer of cells formed at one pole of macrolecithal eggs such as the yolky egg of birds. The yolk prevents the division from taking place through the egg, resulting in meroblastic cleavage during the many cleavage divisions. At the animal pole (containing less yolk than the vegetal pole), the zygote divides and subdivides, forming the blastoderm, which gradually spreads around the yolk and forms the embryo. The blastoderm is composed of two layers, the epiblast and the hypoblast, which enclose the fluid-filled blastocoel cavity." [Wikipedia:Blastoderm] xref: AAO:0000042 ! blastoderm xref: ZFA:0001176 ! blastoderm xref: BTO:0000126 ! blastoderm xref: MESH:A16.254.085.067 ! blastoderm is_a: UBERON:0002050 ! embryonic structure relationship: has_part UBERON:0002532 ! epiblast relationship: has_part UBERON:0000089 ! hypoblast relationship: has_part CL:0000353 ! blastoderm cell relationship: develops_from UBERON:0004749 ! blastodisc xref: TAO:0001176 ! blastoderm [Term] id: UBERON:0000085 name: morula def: "An embryo at an early stage of embryonic development, consisting of cells (called blastomeres) in a solid ball contained within the zona pellucida[WP] The compacted embryo before cavity formation." [Wikipedia:Morula] comment: EHDAA2 has embryo starting later synonym: "morula (2-16 cells)" RELATED [EHDAA2:0000005] xref: ncithesaurus:Morula ! Morula xref: BTO:0001508 ! morula xref: GAID:1295 ! morula xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c6/Blastulation.png/200px-Blastulation.png xref: MESH:A16.254.270.550 ! morula xref: XAO:1000029 ! NF stage 6.5 xref: EHDAA2:0000005 ! morula (2-16 cells) is_a: UBERON:0000922 ! embryo relationship: part_of UBERON:0004716 {source="EHDAA2"} ! conceptus relationship: has_part CL:0000353 ! blastoderm cell relationship: surrounded_by UBERON:0000086 ! zona pellucida xref: SCTID:361474003 ! Morula xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png xref: UMLS:C0026573 [Term] id: UBERON:0000358 name: blastocyst def: "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." [GO:0001824, Wikipedia:Blastocyst] comment: Editor's note: Gilbert fig11.32 has blastocyst has giving rise to ICM and trophoblast (which in this source is a synonym for trophectoderm) synonym: "blastula" RELATED [FMA:83041] xref: BTO:0001099 xref: EFO:0000295 xref: FMA:83041 ! Blastocyst xref: ncithesaurus:Blastocyst ! Blastocyst xref: GAID:1153 ! blastocyst xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/72/Blastocyst_English.svg/200px-Blastocyst_English.svg.png xref: MESH:A16.254.085 ! blastocyst xref: EV:0100394 ! blastocyst is_a: UBERON:0002050 ! embryonic structure relationship: has_part UBERON:0000087 ! inner cell mass relationship: has_part UBERON:0000088 ! trophoblast relationship: part_of UBERON:0000307 ! blastula relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: existence_starts_and_ends_during UBERON:0000108 ! blastula stage xref: SCTID:308837009 ! Entire blastocyst synonym: "blastocystis" RELATED LATIN [Wikipedia:Blastocyst] xref: http://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg xref: UMLS:C1281743 [Term] id: UBERON:0000087 name: inner cell mass def: "Mass of cells inside the primordial embryo that will eventually give rise to the definitive structures of the fetus. This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred. The ICM lies within the blastocoele (more correctly termed \'blastocyst cavity\', as it is not strictly homologous to the blastocoele of anamniote vertebrates) and is entirely surrounded by the single layer of cells called trophoblast." [Wikipedia:Inner_cell_mass] synonym: "embryoblast" RELATED [] synonym: "pluriblast" RELATED [] xref: EFO:0000547 xref: VHOG:0000742 ! inner cell mass xref: FMA:86557 ! Inner cell mass xref: ncithesaurus:Inner_Cell_Mass ! Inner Cell Mass xref: EHDAA:40 ! inner cell mass xref: EHDAA2:0000830 ! inner cell mass xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/72/Blastocyst_English.svg/200px-Blastocyst_English.svg.png xref: EMAPA:16041 ! inner cell mass is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000922 {source="EHDAA2"} ! embryo relationship: develops_from UBERON:0000085 {source="EHDAA2"} ! morula relationship: develops_from UBERON:0000358 {source="Wikipedia"} ! blastocyst relationship: surrounded_by UBERON:0000088 ! trophoblast subset: early_development xref: SCTID:361456007 ! Inner cell mass synonym: "embryoblastus; massa cellularis interna; pluriblastus senior" RELATED LATIN [Wikipedia:Inner_cell_mass] xref: http://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg synonym: "ICM" RELATED [VHOG:0000742] property_value: external_definition "A group of cells found in the mammalian blastocyst that give rise to the embryo. [Biology_Online][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000742", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "A small sphere of cells known as the inner cell mass lies within the trophoblast (of all eutherian mammals).[well established][VHOG]" xsd:string {external_class="VHOG:0000742", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.144", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1283994 [Term] id: UBERON:0000088 name: trophoblast def: "Aggregate of cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg." [Wikipedia:Trophoblast] comment: Development notes: The postimplantation derivatives of the trophectoderm, which make up most of the fetal part of the placenta[PMID:19829370] synonym: "trophoblast layer" RELATED [MP:0005031] synonym: "trophoderm" RELATED [BTO:0001079] synonym: "trophoblastus" RELATED LATIN [Wikipedia:Trophoblast] synonym: "massa cellularis externa" RELATED LATIN [Wikipedia:Trophoblast] xref: BTO:0001079 xref: FMA:83029 ! Trophoblast xref: GAID:1152 ! trophoblast xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/72/Blastocyst_English.svg/200px-Blastocyst_English.svg.png xref: MESH:A11.936 ! trophoblast xref: EV:0100120 ! trophoblast is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000358 ! blastocyst relationship: composed_primarily_of CL:0000351 ! trophoblast cell relationship: develops_from UBERON:0004345 {source="MP-def", source="PMID:19829370"} ! trophectoderm subset: early_development xref: SCTID:362839005 ! Entire trophoblast xref: ncithesaurus:Trophoblast ! trophoblast xref: http://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg property_value: external_definition "the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta[MP]" xsd:string {ontology="MP", external_class="MP:0005031", external_class_label="trophoblast layer", date_retrieved="2012-08-23", source="ISBN:0-683-40008-8"} property_value: has_relational_adjective "trophoblastic" xsd:string xref: UMLS:C0041178 [Term] id: UBERON:0004345 ! trophectoderm name: trophectoderm def: "outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition" [MP:0005028] comment: Editor notes: distinction between trophectoderm and trophoblast unclear/inconsistent in many sources. AO notes: BTO has this has part of the trophoblast xref: EMAPA:16046 ! trophectoderm xref: BTO:0001840 ! trophectoderm xref: VHOG:0000979 ! trophectoderm xref: EHDAA2:0002091 ! trophectoderm xref: EHDAA:56 ! trophectoderm is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0000085 {source="EHDAA2"} ! morula relationship: part_of UBERON:0005631 {source="EHDAA2"} ! extraembryonic membrane relationship: has_part CL:1000274 ! trophectodermal cell subset: early_development property_value: external_definition "The outer cellular layer of the mammalian blastocyst. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.750, see_Kardong_KV][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000979", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the trophoblast develops rapidly so that contact may be made with the maternal uterine tissues when conditions are appropriate. We have here an excellent example of an embryonic adaptation, the development of a structure never present in either adult or embryo of 'lower' vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000979", ontology="VHOG", source="ISBN:978-0721676685 Romer AS\, Parsons TS\, Vertebrate body (1977) p.105-106", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "trophectodermal" xsd:string [Term] id: UBERON:0006280 name: polar trophectoderm def: "Trophectoderm that surrounds the inner cell mass (ICM)." [PMID:16341078] subset: emapa_ehdaa2 xref: EMAPA:16048 ! polar trophectoderm xref: EHDAA2:0001484 ! polar trophectoderm xref: VHOG:0000980 ! polar trophectoderm xref: EHDAA:60 ! polar trophectoderm is_a: UBERON:0000478 ! extraembryonic structure relationship: develops_from UBERON:0004345 {source="EHDAA2"} ! trophectoderm relationship: part_of UBERON:0004345 {source="EMAPA"} ! trophectoderm relationship: adjacent_to UBERON:0000087 ! inner cell mass subset: early_development synonym: "polar trophoblast" RELATED [VHOG:0000980] property_value: external_definition "The part of the trophectoderm overlying the inner cell mass. [See_Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.10][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000980", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the trophoblast develops rapidly so that contact may be made with the maternal uterine tissues when conditions are appropriate. We have here an excellent example of an embryonic adaptation, the development of a structure never present in either adult or embryo of 'lower' vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000980", ontology="VHOG", source="ISBN:978-0721676685 Romer AS\, Parsons TS\, Vertebrate body (1977) p.105-106", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006265 name: mural trophectoderm def: "Trophectoderm that surrounds blastocyst cavity." [PMID:16341078] subset: emapa_ehdaa2 xref: EMAPA:16047 ! mural trophectoderm xref: EHDAA2:0001206 ! mural trophectoderm xref: VHOG:0000597 ! mural trophectoderm xref: EHDAA:58 ! mural trophectoderm is_a: UBERON:0000478 ! extraembryonic structure relationship: part_of UBERON:0004345 {source="EMAPA"} ! trophectoderm relationship: part_of UBERON:0004345 ! trophectoderm relationship: surrounds UBERON:0000090 ! blastocele subset: early_development synonym: "mural trophoblast" RELATED [VHOG:0000597] property_value: external_definition "The part of the trophectoderm which surrounds the blastocoelic cavity. [See_Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.10][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000597", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the trophoblast develops rapidly so that contact may be made with the maternal uterine tissues when conditions are appropriate. We have here an excellent example of an embryonic adaptation, the development of a structure never present in either adult or embryo of 'lower' vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000597", ontology="VHOG", source="ISBN:978-0721676685 Romer AS\, Parsons T\, Vertebrate body (1977) p.105-106", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000089 name: hypoblast (generic) def: "." [Wikipedia:Hypoblast, https://sourceforge.net/tracker/?func=detail&aid=3560500&group_id=36855&atid=440764] comment: this term groups together disparate structures with different relationships. TODO - consider relationship to UBERON:0000091 ! bilaminar disc subset: grouping_class subset: uberon_slim subset: vertebrate_core synonym: "mesendoderm" RELATED [ZFIN:ZDB-PUB-961014-576] synonym: "hypoblastus" RELATED LATIN [Wikipedia:Hypoblast] synonym: "endomesoderm" RELATED [VHOG:0001222] synonym: "hypoblast" EXACT [VHOG:0001222] xref: AAO:0000229 ! hypoblast xref: VHOG:0001222 ! hypoblast xref: MAT:0000418 ! hypoblast xref: MIAA:0000418 ! hypoblast xref: TAO:0000117 ! hypoblast xref: XAO:0003044 ! endomesoderm xref: ZFA:0000117 ! hypoblast xref: ncithesaurus:Hypoblast ! Hypoblast xref: EFO:0001930 ! hypoblast xref: http://upload.wikimedia.org/wikipedia/commons/0/02/Cell_differentiation_gastrula.PNG xref: BTO:0003953 ! endomesoderm is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004750 ! blastoderm subset: early_development xref: AAO:0010619 ! endomesoderm xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png property_value: external_definition "A primary germ layer that can give rise to both mesoderm and endoderm.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010619", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "The inner of the two layers of the blastoderm that forms during gastrulation and give rise to the definitive mesoderm and endoderm. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000117", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "In mammal and avian, extraembryonic endoderm such as visceral endoderm and hypoblast play essential roles in the embryonic axis formation and germ layer development. These extraembryonic tissues are generally considered to have been created in ancestral amniotes evolved from the Xenopus-type ancestor (reference 1); The endomesoderm secretes as yet unidentified signals that posteriorize the ectoderm, which would otherwise adopt an anterior fate. Our results point to a conserved function at the base of deuterostomes for beta-catenin in germ layer specification and to a causal link in the definition of the posterior part of the embryonic ectoderm by way of activating posteriorizing endomesodermal factors (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001222", ontology="VHOG", source="DOI:10.1016/j.ydbio.2009.05.543 Takeuchi M\, Takahashi M\, Okabe M\, Aizawa S\, Germ layer patterning in bichir and lamprey; an insight into its evolution in vertebrates. Developmental Biology (2009) (reference 1)\, Darras S\, Gerhart J\, Terasaki M\, Kirschner M\, Lowe CJ\, Beta-catenin specifies the endomesoderm and defines the posterior organizer of the hemichordate Saccoglossus kowalevskii. Development (2011) (reference 2)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1512561 [Term] id: UBERON:0008776 name: inner cell mass derived hypoblast alt_id: UBERON:0000417 alt_id: UBERON:0003226 alt_id: UBERON:0003225 def: "The hypoblast is a tissue type that forms from the inner cell mass. It lies beneath the epiblast and consists of small cuboidal cells. Extraembryonic endoderm is derived from hypoblast." [Wikipedia:Hypoblast] comment: Note this inherits the taxon constraint to Theria; this may be too conservative synonym: "hypoblast" RELATED SENSU [ISBN:9780878932504, GO:0090008, VHOG:0001222] synonym: "primary endoderm" RELATED [MP:0011185] synonym: "primitive endoderm" EXACT [ISBN:9780878932504, MP:0011185] synonym: "visceral endoderm" RELATED [ISBN:9780878932504] is_a: UBERON:0000089 ! hypoblast relationship: adjacent_to UBERON:0002532 ! epiblast relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass xref: EHDAA2:0000796 ! hypoblast xref: BTO:0002123 xref: FMA:85520 ! Primitive endoderm xref: EHDAA:44 ! primitive endoderm xref: EHDAA:79 ! primitive endoderm xref: EMAPA:16051 ! primitive endoderm of embryo xref: EMAPA:16063 ! primitive endoderm of endoderm of embryo subset: early_development [Term] id: UBERON:0004046 name: anterior definitive endoderm def: "the mesendoderm which first migrates from the node and which gives rise to the gut" [MP:0008926] comment: TODO - check is_a: UBERON:0000089 ! hypoblast [Term] id: UBERON:0008800 name: parietal endoderm synonym: "distal endoderm" RELATED [EMAPA:16053] def: "primitive endoderm-derived tissue that lines the luminal surface of the mural trophectoderm[MP]" [PMID:19201946, MP:0011187] xref: EMAPA:16053 ! parietal endoderm is_a: UBERON:0000478 ! extraembryonic structure relationship: develops_from UBERON:0008780 {source="MP"} ! inner cell mass derived epiblast [Term] id: UBERON:0004877 name: visceral endoderm def: "Visceral endoderm, a population of extraembyonic endoderm, is an extraembryonic tissue that functions in a regulatory capacity but does not contribute directly to the formation of any adult organs[PMID:15905405]. primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut[MP]." [PMID:15905405, MP:0011186] comment: Note: Gilbert uses visceral endoderm as a synonym for primitive endoderm/hypoblast xref: EMAPA:16058 ! visceral endoderm xref: BTO:0003487 ! visceral endoderm is_a: UBERON:0005292 {source="BTO"} ! extraembryonic tissue relationship: develops_from UBERON:0000925 ! endoderm [Term] id: UBERON:0004044 name: anterior visceral endoderm def: "the extraembryonic tissue that is responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate patterning of adjacent embryonic tissue" [MP:0008533] comment: see also primitive streak synonym: "AVE" RELATED [BTO:0003361] xref: BTO:0003361 ! anterior visceral endoderm is_a: UBERON:0000478 ! extraembryonic structure relationship: develops_from UBERON:0000925 ! endoderm [Term] id: UBERON:0004878 name: distal visceral endoderm def: "precursors of the anterior visceral endoderm that arises at the distal tip of the embryo[MP]" [MP:0010126] is_a: UBERON:0000478 ! extraembryonic structure relationship: develops_from UBERON:0000925 ! endoderm [Term] id: UBERON:0008945 name: extraembryonic endoderm def: "An extraembryonic epithelium that is formed by the delaminated cells of the primitive endoderm (hypoblast) that goes on to form the yolk sac. In mammals, as in avians, these cells do not produce any part of the newborn organism (i.e. they are extraembryonic)" [http://www.ana.ed.ac.uk/database/humat/notes/extraemb/mesoder.htm, ISBN:9780878932504, UBERON:cjm] comment: The origin of extraembryonic endoderm is a highly controversial issue // forms the yolk sac (Gilbert) is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0008776 {source="EHDAA2", source="ISBN:9780878932504", gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! inner cell mass derived hypoblast xref: EHDAA:105 ! extraembryonic endoderm xref: EHDAA2:0000473 ! extraembryonic endoderm xref: EMAPA:16052 ! endoderm of extraembryonic component [Term] id: UBERON:0005728 name: extraembryonic mesoderm def: "." [http://www.ana.ed.ac.uk/database/humat/notes/extraemb/mesoder.htm] synonym: "extra-embryonic mesoderm" EXACT [] synonym: "extraembryonic mesenchyme" EXACT [] xref: EHDAA2:0000474 ! extraembryonic mesoderm xref: VHOG:0000616 ! extraembryonic mesoderm is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure relationship: develops_from UBERON:0008780 {source="EHDAA2"} ! inner cell mass derived epiblast relationship: develops_from UBERON:0003081 ! lateral plate mesoderm [Term] id: UBERON:0004366 name: extraembryonic ectoderm comment: Editor note: we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion. def: "layer of the endoderm of the extraembryonic tissue." [MP:0002583] xref: EMAPA:16065 ! ectoderm of extraembryonic component is_a: UBERON:0000478 ! extraembryonic structure is_a: UBERON:0000478 {source="cjm"} ! extraembryonic structure relationship: develops_from UBERON:0000924 ! ectoderm [Term] id: UBERON:0000090 ! blastocele name: blastocele def: "fluid-filled central region of a blastocyst. A blastocoele forms during embryogenesis when a zygote (a fertilized ovum) divides into many cells through mitosis." [Wikipedia:Blastocele] synonym: "blastocoele" EXACT [] synonym: "blastocyst cavity" EXACT [] synonym: "cleavage cavity" EXACT [] synonym: "segmentation cavity" EXACT [] synonym: "blastocoelic cavity" EXACT [EHDAA2:0000175] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Blastocyst.gif/200px-Blastocyst.gif xref: EMAPA:16044 ! blastocoelic cavity xref: EHDAA2:0000175 ! blastocoelic cavity xref: XAO:0000294 ! blastocoel xref: VHOG:0000811 ! blastocoelic cavity xref: EHDAA:50 ! blastocoelic cavity is_a: UBERON:0002553 ! anatomical cavity relationship: surrounded_by UBERON:0002532 ! epiblast relationship: dubious_for_taxon NCBITaxon:7955 {source="http://zfin.org/zf_info/zfbook/stages/gast.html"} ! Danio rerio subset: early_development xref: AAO:0010433 ! blastocoel xref: SCTID:361455006 ! Blastocyst cavity property_value: external_definition "A blastocoel forms during embryogenesis when a zygote (a fertilized ovum) divides into many cells through mitosis. The blastocoel is the cavity of the blastula, a closed space which is invaded by early mesenchyme and later obliterated by the enlarging archenteron.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010433", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0", source="ISBN:0815318960"} synonym: "blastocoel" RELATED [VHOG:0000811] property_value: external_definition "The cavity inside the blastula. [The_evolution_of_organ_systems_(2007)_Oxford:_Oxford_University_Press, p.150, see_Schmidt-Rhaesa_A][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000811", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In the development of many animals, a hollow blastula stage is formed during early embryogenesis. Such a hollow blastula is even regarded as an autapomorphy of Metazoa and is present already in some sponges.[well established][VHOG]" xsd:string {external_class="VHOG:0000811", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.150", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000091 name: bilaminar disc def: "the epiblast and the hypoblast, evolved from the embryoblast" [Wikipedia:Bilaminar_disc] synonym: "bilaminary embryonic disc" EXACT [] synonym: "bilaminary germ disc" EXACT [ISBN:9780878932504] synonym: "bilaminar disk" RELATED [Wikipedia:Bilaminar_disc] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Gray21.png/200px-Gray21.png xref: ncithesaurus:Bilaminar_Embryonic_Disc ! Bilaminar Embryonic Disc is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass subset: early_development xref: UMLS:C1283997 [Term] id: UBERON:0000093 name: sulcus def: "a depression or fissure in the surface of an organ." [Wikipedia:Sulcus_(anatomy)] is_a: UBERON:0000464 ! anatomical space subset: grouping_class subset: non_informative created_by: cjm creation_date: 2009-04-09T06:23:22Z [Term] id: UBERON:0013118 name: sulcus of brain def: "a depression or fissure in the surface of the brain. It surrounds the gyri, creating the characteristic appearance of the brain in humans and other large mammals." [Wikipedia:Sulcus_(neuroanatomy)] synonym: "fissure of brain" NARROW [Wikipedia:Sulcus_(neuroanatomy)] intersection_of: UBERON:0000093 ! sulcus intersection_of: part_of UBERON:0000955 ! brain [Term] id: UBERON:0000094 name: membrane organ def: "Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]" [FMA:7145] synonym: "membrane of organ" EXACT [] xref: FMA:7145 ! Membrane organ is_a: UBERON:0000062 ! organ created_by: cjm creation_date: 2009-07-30T05:19:13Z [Term] id: UBERON:0000095 ! cardiac neural crest name: cardiac neural crest def: "portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]" [Wikipedia:Cardiac_neural_crest] comment: AO notes - ZFA treats this as a subtype of NC. subset: vertebrate_core synonym: "cardiac neural crest complex" RELATED [Wikipedia:Cardiac_neural_crest] synonym: "complexus cristae neuralis cardiacus" RELATED [Wikipedia:Cardiac_neural_crest] xref: ZFA:0001648 ! cardiac neural crest is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0002342 ! neural crest relationship: overlaps UBERON:0005428 {source="Wikipedia"} ! vagal neural crest created_by: cjm creation_date: 2009-07-30T07:57:38Z xref: XAO:0004190 ! cardiac neural crest xref: TAO:0002173 ! cardiac neural crest [Term] id: UBERON:0005428 ! vagal neural crest name: vagal neural crest def: "Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]." [ZFIN:curator] subset: vertebrate_core subset: vertebrate_core synonym: "post-otic neural crest" EXACT [ZFA:0000818] xref: EHDAA2:0002156 ! vagal neural crest xref: EHDAA:669 ! vagal neural crest xref: VHOG:0001208 ! vagal neural crest xref: TAO:0000818 ! vagal neural crest xref: ZFA:0000818 ! vagal neural crest is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0002342 ! neural crest xref: XAO:0004191 ! vagal neural crest property_value: external_definition "Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000818", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001208", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000101 name: lobe of lung def: "A lung lobe is one of the rounded projections that compose the lung[GO]." [GOC:GO] synonym: "lung lobe" EXACT [] synonym: "pulminory lobe" EXACT [] synonym: "pulmonary lobe" EXACT [FMA:7311] xref: FMA:7311 ! Lobe of lung xref: ncithesaurus:Lung_Lobe ! Lung Lobe xref: galen:LobeOfLung ! lobe of lung xref: OpenCyc:Mx4rvo6-vpwpEbGdrcN5Y29ycA ! lung lobe is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002048 ! lung xref: SCTID:245524004 ! Entire lobe of lung xref: UMLS:C0225752 [Term] id: UBERON:0000102 name: lung vasculature def: "The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]." [GOC:GO] synonym: "lung vascular network" EXACT [OBOL:automatic] synonym: "vascular network of lung" EXACT [OBOL:automatic] synonym: "vasculature of lung" EXACT [OBOL:automatic] synonym: "pulmonary vasculature" EXACT [FMA:73750] xref: FMA:73750 ! Vasculature of lung is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002048 ! lung [Term] id: UBERON:0000103 name: life cycle stage boundary def: "Instant starting or ending a life cycle stage. These can be arbitrary/fiat." [UBERON:cjm] subset: upper_level synonym: "life cycle stage transition event" EXACT [] synonym: "life cycle stage transition instant" EXACT [] xref: span:ProcessBoundary is_a: UBERON:0000000 ! processual entity disjoint_from: UBERON:0000105 ! life cycle stage [Term] id: UBERON:0000104 name: life cycle def: "An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism." [UBERON:cjm] subset: upper_level synonym: "life" EXACT [] synonym: "lifespan" EXACT [] xref: FBdv_root:00000000 xref: OGES:000011 xref: MmusDv:0000000 xref: HsapDv:0000000 xref: ncithesaurus:Life ! Life is_a: UBERON:0000105 ! life cycle stage [Term] id: UBERON:0000105 name: life cycle stage def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [UBERON:cjm] comment: Editor notes: we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage subset: upper_level synonym: "developmental stage" EXACT [] synonym: "stage" NARROW [] xref: BILS:0000105 xref: EFO:0000399 xref: XAO:1000000 ! Xenopus developmental stage xref: ZFS:0100000 ! zebrafish stage xref: ZFS:0000000 ! Unknown xref: WBls:0000002 ! all stages xref: OlatDv:0000010 xref: MmusDv:0000001 ! mouse life cycle xref: ncithesaurus:Developmental_Stage ! Developmental Stage is_a: UBERON:0000000 ! processual entity relationship: has_end UBERON:0000103 ! life cycle stage boundary relationship: has_start UBERON:0000103 ! life cycle stage boundary [Term] id: UBERON:0000106 name: zygote stage def: "A stage at which the organism is a single cell produced by means of sexual reproduction." [Wikipedia:Zygote] synonym: "one cell stage" EXACT [] synonym: "1-cell stage" EXACT [] synonym: "fertilized egg stage" EXACT [BTO:0000854] xref: BILS:0000106 xref: ZFS:0000001 ! Zygote:1-cell xref: VHOG:0000745 ! one-cell stage xref: EMAPA:16033 ! one-cell stage xref: XAO:1000001 ! NF stage 1 xref: EHDAA:27 ! one-cell stage is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: starts UBERON:0000104 ! life cycle synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] synonym: "zygote" RELATED [VHOG:0000745] synonym: "fertilized egg stage" RELATED [] synonym: "one-cell stage" RELATED [VHOG:0000745] property_value: homology_notes "As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]" xsd:string {external_class="VHOG:0000745", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.107", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: EFO:0001322 ! fertilized egg stage xref: BilaDO:0000005 ! zygote xref: FBdv:00005288 ! fertilized egg stage [Term] id: UBERON:0000107 name: cleavage stage def: "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." [GO:0040016, Wikipedia:Cleavage_(embryo)] xref: BILS:0000107 xref: XAO:1000004 ! cleavage stage xref: EFO:0001290 ! cleavage stage xref: MESH:A16.254.270 ! ovum cleavage stage xref: OGES:000015 xref: OGES:000020 xref: BilaDO:0000006 ! cleavage xref: MmusDv:0000004 ! cleavage xref: ZFS:0000046 ! cleavage intersection_of: UBERON:0000105 ! life cycle stage intersection_of: simultaneous_with GO:0040016 relationship: part_of UBERON:0000068 ! embryo stage relationship: immediately_preceded_by UBERON:0000106 ! zygote stage [Term] id: UBERON:0007232 ! 2-cell stage name: 2 cell stage synonym: "two-cell stage" EXACT [OBOL:automatic] synonym: "NF stage 2 (2-cell)" NARROW SENSU [XAO:1000011] xref: EMAPA:16036 ! two-cell stage xref: XAO:1000011 ! NF stage 2 (2-cell) xref: ZFS:0000002 ! Cleavage:2-cell xref: XtroDO:0000006 ! NF stage 2 (2-cell) is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000107 ! cleavage stage relationship: immediately_preceded_by UBERON:0000106 ! zygote stage [Term] id: UBERON:0007233 name: 4 cell stage synonym: "four-cell stage" EXACT [OBOL:automatic] synonym: "NF stage 3 (4-cell)" NARROW SENSU [XAO:1000013] xref: ZFS:0000003 ! xref: XAO:1000013 ! NF stage 3 (4-cell) xref: XtroDO:0000007 ! NF stage 3, 4-cell stage is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000107 ! cleavage stage relationship: starts UBERON:0007234 ! 4-8 cell stage relationship: immediately_preceded_by UBERON:0007232 ! two-cell stage [Term] id: UBERON:0007236 name: 8 cell stage synonym: "eight-cell stage" EXACT [OBOL:automatic] synonym: "NF stage 4 (8-cell)" NARROW SENSU [XAO:1000014] xref: ZFS:0000004 xref: XAO:1000014 ! NF stage 4 (8-cell) xref: XtroDO:0000008 ! NF stage 4, 8-cell stage is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000107 ! cleavage stage relationship: finishes UBERON:0007234 ! 4-8 cell stage relationship: immediately_preceded_by UBERON:0007233 ! 4-cell stage [Term] id: UBERON:0007234 ! 4-8 cell stage name: 4-8 cell stage synonym: "four-eight cell stage" EXACT [OBOL:automatic] xref: EMAPA:16037 ! 4-8 cell stage is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000107 ! cleavage stage relationship: immediately_preceded_by UBERON:0007232 ! two-cell stage [Term] id: UBERON:0000108 name: blastula stage def: "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] xref: BILS:0000108 xref: XAO:1000003 ! blastula stage xref: OGES:000021 ! blastula xref: OGES:000016 ! blastula xref: OGES:000003 ! Blastula xref: OpenCyc:Mx4rEetFnKP2EdqAAAACs4vPlg ! blastula xref: EFO:0001282 ! blastula stage xref: BilaDO:0000007 ! blastula xref: MmusDv:0000007 ! blastula xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c6/Blastulation.png/200px-Blastulation.png is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000107 ! cleavage stage xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png xref: HsapDv:0000006 ! blastula stage xref: ZFS:0000045 ! blastula [Term] id: UBERON:0000109 ! gastrula stage name: gastrula stage def: "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GO:0007369] synonym: "trilaminar stage" RELATED [UBERON:cjm] synonym: "trilaminar disk stage" RELATED [UBERON:cjm] synonym: "trilaminar germ stage" RELATED [UBERON:cjm] synonym: "trilaminar blastoderm stage" RELATED [UBERON:cjm] synonym: "blastocystis trilaminaris stage" RELATED [UBERON:cjm] synonym: "trilaminar blastocyst stage" RELATED [UBERON:cjm] xref: BILS:0000109 xref: XAO:1000005 ! gastrula stage xref: FBdv:00005317 ! gastrula stage xref: EFO:0001296 ! gastrula stage xref: OGES:000004 xref: OGES:000019 xref: BilaDO:0000008 ! gastrula xref: MmusDv:0000013 ! gastrula xref: HsapDv:0000010 ! gastrula stage xref: ZFS:0000047 ! gastrula is_a: UBERON:0000105 ! life cycle stage relationship: simultaneous_with GO:0007369 relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000108 {source="BILS"} ! blastula stage [Term] id: UBERON:0004455 name: neurula embryo alt_id: UBERON:0007013 def: "An embryo at the neurula stage." [GOC:cjm] synonym: "neurula" EXACT [BTO:0001766] xref: ncithesaurus:Neurula xref: BTO:0001766 ! neurula xref: BILA:0000061 ! neurula embryo is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0000110 ! neurula stage relationship: develops_from UBERON:0004734 ! gastrula xref: UMLS:C1518306 [Term] id: UBERON:0000110 name: neurula stage def: "Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GO:0001841] xref: BILS:0000110 xref: XAO:1000006 ! neurula stage xref: BilaDO:0000009 ! neurula xref: MmusDv:0000016 ! neurula xref: HsapDv:0000012 ! neurula stage is_a: UBERON:0000105 ! life cycle stage relationship: simultaneous_with GO:0001841 relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000109 ! gastrula stage [Term] id: UBERON:0000111 name: organogenesis stage def: "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [Wikipedia:Organogenesis] synonym: "segmentation stage" RELATED [] xref: BILS:0000111 xref: OGES:000005 xref: OGES:000032 xref: BilaDO:0000010 ! organogenesis xref: MmusDv:0000018 ! organogenesis xref: HsapDv:0000015 ! organogenesis stage is_a: UBERON:0000105 ! life cycle stage relationship: simultaneous_with GO:0048513 ! organ development relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000110 ! neurula stage [Term] id: UBERON:0004707 name: pharyngula stage def: "A stage that follows the blastula, gastrula and neurula stages. At the pharyngula stage, all vertebrate embryos show remarkable similarities." [Wikipedia:Pharyngula] comment: Corresponds to E7-E11 in Mouse (Galis et al, TREE, 2001) synonym: "phylotypic stage" EXACT [] synonym: "pharyngula" RELATED [] xref: OGES:000006 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000110 ! neurula stage xref: EFO:0001310 ! pharyngula stage xref: DrerDO:0000052 ! Pharyngula xref: ZFS:0000050 ! pharyngula [Term] id: UBERON:0000066 name: fully formed stage def: "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both juvenile stage, and adult stage. " [UBERON:cjm] synonym: "fully formed animal stage" EXACT [] synonym: "juvenile-adult stage" EXACT [] synonym: "adult stage" BROAD [] xref: FBdv:00005369 xref: WBls:0000041 ! adult xref: BTO:0001043 ! adult is_a: UBERON:0000092 ! post-embryonic stage relationship: preceded_by UBERON:0000111 ! organogenesis stage xref: EFO:0001272 ! adult xref: BilaDO:0000004 ! adult xref: XtroDO:0000084 ! adult [Term] id: UBERON:0000112 ! juvenile stage name: juvenile stage comment: Consider renaming this to '(sexually) immature stage'; in mammals this would include infant (nourishment from lactation) and juvenile (prepubertal no longer dependent on mother) synonym: "immature stage" EXACT [VHOG:FB] xref: BILS:0000112 xref: XAO:1000010 ! juvenile stage xref: ZFS:0000051 ! juvenile xref: EFO:0001300 ! juvenile stage xref: BTO:0002168 ! juvenile xref: EV:0300051 ! child xref: OGES:000009 xref: XtroDO:0000083 ! juvenile xref: TS28 ! TS28 (P0-Adult) is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000066 ! fully formed stage relationship: preceded_by UBERON:0000069 {gci_relation="part_of", gci_filler="NCBITaxon:7955", source="ZFS"} ! larval stage property_value: external_definition "The stage of being a sexually immature adult animal[XAO:1000010]." xsd:string {source="XAO:1000010"} [Term] id: UBERON:0000113 name: post-juvenile adult stage def: "The stage of being a sexually mature adult animal." [UBERON:cjm] synonym: "adult stage" BROAD [] xref: BILS:0000113 xref: MIAA:0000403 ! adult stage xref: ZFS:0000044 ! adult xref: XAO:1000009 ! adult stage xref: EV:0300070 ! adult xref: OGES:000026 ! adolescent xref: OGES:000027 ! adult xref: EV:0300064 ! adolescent xref: MmusDv:0000039 ! adolescent xref: MmusDv:0000040 ! adult is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000066 ! fully formed stage relationship: preceded_by UBERON:0000112 ! juvenile stage xref: EFO:0001272 ! adult [Term] id: UBERON:0007222 name: late adult stage synonym: "geriatric stage" RELATED [EV:0300123] synonym: "geriatric" RELATED [EV:0300123] synonym: "elderly" RELATED [EV:0300123] synonym: "elderly stage" RELATED [EV:0300123] xref: EV:0300123 ! elderly xref: NIF_Organism:birnlex_691 ! Elderly is_a: UBERON:0000113 ! post-juvenile adult stage xref: ncithesaurus:Elderly ! Elderly xref: HsapDv:0000093 ! aged stage xref: UMLS:C0001792 [Term] id: UBERON:0007221 name: neonate stage def: "Of or pertaining to the period of time immediately following birth, or to the newborn." [Wikipedia:Infant, http://en.wiktionary.org/wiki/neonatal] comment: Editor note: consider splitting infant/newborn synonym: "neonatal stage" EXACT [OBOL:automatic] synonym: "infant stage" NARROW SENSU [UBERON:cjm] synonym: "hatchling stage" NARROW SENSU [UBERON:cjm] synonym: "nestling stage" NARROW SENSU [UBERON:cjm] synonym: "fledgling stage" NARROW SENSU [UBERON:cjm] synonym: "hatchling" NARROW SENSU [UBERON:cjm] synonym: "newborn stage" RELATED [UBERON:cjm] xref: BTO:0001762 ! neonate xref: EV:0300037 ! infant xref: NIF_Organism:birnlex_695 ! Infant xref: http://neurolex.org/wiki/Category:Newborn_organism xref: http://neurolex.org/wiki/Category:Infant_organism xref: OGES:000025 xref: MmusDv:0000038 ! infant xref: HsapDv:0000082 ! newborn stage xref: HsapDv:0000083 ! infant stage is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000112 ! juvenile stage [Term] id: UBERON:0007006 name: obsolete blastomere def: "a type of cell produced by division of the egg after fertilization." [Wikipedia:Blastomere] consider: BILA:0000052 ! blastomere consider: XAO:0003016 ! blastomere consider: ZFA:0000093 ! blastomere consider: VHOG:0001221 ! blastomere consider: FMA:72551 ! Blastomere is_obsolete: true replaced_by: CL:0000353 [Term] id: UBERON:0007010 name: cleaving embryo def: "Organism at the cleavage stage." [OBOL:automatic] xref: BILA:0000058 ! cleaving embryo is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_ends_with UBERON:0000107 ! cleavage stage intersection_of: existence_starts_with UBERON:0000107 ! cleavage stage [Term] id: UBERON:0007021 name: juvenile organism def: "A multi-cellular organism that is at the juvenile stage." [OBOL:automatic] synonym: "juvenile" BROAD [] xref: BILA:0000076 ! juvenile organism is_a: UBERON:0000468 ! multi-cellular organism intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_ends_with UBERON:0000112 ! juvenile stage intersection_of: existence_starts_with UBERON:0000112 ! juvenile stage xref: TAO:0002047 ! juvenile xref: http://neurolex.org/wiki/Category:Juvenile_organism property_value: external_definition "Whole organism that is not fully grown or sexually mature.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002047", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "juveniles" EXACT PLURAL [TAO:0002047] [Term] id: UBERON:0007023 ! adult organism name: adult organism synonym: "adult" BROAD [] xref: BILA:0000078 ! adult organism xref: HAO:0000087 ! adult xref: FBbt:00003004 ! adult is_a: UBERON:0000468 ! multi-cellular organism intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_ends_with UBERON:0000113 ! post-juvenile adult stage intersection_of: existence_starts_with UBERON:0000113 ! post-juvenile adult stage xref: ncithesaurus:Adult ! Adult xref: galen:Adult xref: TAO:0002046 ! adult xref: http://neurolex.org/wiki/Category:Adult_organism property_value: external_definition "Whole organism that is fully grown or sexually mature.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002046", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "adults" EXACT PLURAL [TAO:0002046] def: "A multi-cellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage." [OBOL:automatic] xref: UMLS:C0001675 [Term] id: UBERON:0011942 ! adult human name: obsolete adult human is_obsolete: true [Term] id: UBERON:0009953 ! post-embryonic organism name: post-embryonic organism synonym: "post-natal organism" NARROW [UBERON:cjm] synonym: "post-hatching organism" NARROW [UBERON:cjm] intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_with UBERON:0000092 ! post-embryonic stage xref: MA:0002405 ! postnatal mouse synonym: "postnatal mouse" NARROW [MA:0002405] synonym: "TS28 mouse" NARROW [MA:0002405] def: "A multi-cellular organism that existence_starts_with a post-embryonic stage." [OBOL:automatic] [Term] id: UBERON:0009096 name: gravid stage comment: Obsoleted as the gravid stage is not a life cycle stage. A similar term may be recreated when we have stages specific to structures such as the uterus is_obsolete: true consider: UBERON:0009097 [Term] id: UBERON:0009097 name: gravid organism def: "An organism containing a developing embryo, fetus, or unborn offspring within the body." [BTO:0004733] synonym: "pregnant organism" RELATED [] synonym: "gravid" RELATED [BTO:0004733] synonym: "pregnant stage" RELATED [BTO:0004733] synonym: "pregnant adult stage" RELATED [BTO:0004733] intersection_of: UBERON:0007023 ! adult organism intersection_of: has_part UBERON:0000922 ! embryo relationship: participates_in GO:0007565 ! female pregnancy xref: BTO:0004733 ! gravid adult [Term] id: UBERON:0000114 name: lung connective tissue def: "A portion of connective tissue that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of lung" EXACT [OBOL:automatic] synonym: "lung portion of connective tissue" EXACT [OBOL:automatic] synonym: "lung textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lung" EXACT [OBOL:automatic] synonym: "textus connectivus of lung" EXACT [OBOL:automatic] synonym: "lung interstitial tissue" RELATED [MA:0001782] xref: MA:0001782 ! lung connective tissue is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002048 ! lung xref: SCTID:201609008 ! Entire interstitial tissue of lung [Term] id: UBERON:0000115 name: lung epithelium def: "the epithelial layer of the lung." [MP:0006382] synonym: "epithelial tissue of lung" EXACT [OBOL:automatic] synonym: "epithelium of lung" EXACT [OBOL:automatic] synonym: "lung epithelial tissue" EXACT [OBOL:automatic] synonym: "pulmonary epithelium" RELATED [BTO:0001653] xref: MA:0001783 ! lung epithelium xref: BTO:0001653 ! lung epithelium is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002048 ! lung relationship: develops_from UBERON:0001041 ! foregut [Term] id: UBERON:0000116 name: lung saccule def: "Primitive gas exchange portion of the lung composed of type I and type II cells[GO]." [GO:0060430] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002299 {source="GO"} ! alveolus of lung [Term] id: UBERON:0006859 name: swim bladder bud def: "Embryonic structure that forms from the anterior gut epithelium at the level of the second somite that then matures to form the swim bladder." [ZFIN:ZDB-PUB-090511-18, ZFIN:ZDB-PUB-100202-11] xref: TAO:0005335 ! swim bladder bud xref: ZFA:0005335 ! swim bladder bud is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0000119 name: cell layer def: "Portion of tissue, that consists of one or more layers of cells connected to each other by cell junctions" [UBERON:cjm] synonym: "cell sheath" RELATED [] synonym: "layer of cells" EXACT [] subset: upper_level is_a: UBERON:0000479 ! portion of tissue relationship: has_part CL:0000213 ! lining cell [Term] id: UBERON:0000120 name: blood brain barrier def: "Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions." [DOI:10.1002/glia.20642, Wikipedia:Blood-brain_barrier] synonym: "BBB" RELATED [] synonym: "blood-brain barrier" EXACT [] xref: ncithesaurus:Blood-Brain_Barrier ! Blood-Brain Barrier is_a: UBERON:0000119 ! cell layer relationship: adjacent_to UBERON:0000179 ! haemolymphatic fluid relationship: adjacent_to UBERON:0000955 ! brain xref: UMLS:C0005854 [Term] id: UBERON:0011893 ! endoneurial fluid name: endoneurial fluid def: "Fluid of the ganglia and peripheral nerves that lie outside the brain and spinal cord" [MGI:llw2, MP:0003633] is_a: UBERON:0007794 {source="FMA"} ! serous fluid intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: located_in UBERON:0000123 ! endoneurium [Term] id: UBERON:0000121 name: perineurium def: "Connective tissue surrounding a fascicle." [Wikipedia:Perineurium] comment: consider FBbt:00007090 (perineurium): The outer two layers of glial cells that cover the central nervous system and the nerves. The outer layer is the perineurial sheath (sometimes referred to as the perineurial sheath outer layer); the inner layer is the sub-perineural glial sheath (sometimes referred to as the perineurial sheath inner layer) xref: FMA:52585 ! Perineurium xref: ncithesaurus:Perineurium ! Perineurium xref: BTO:0003153 ! perineurium xref: NIF_GrossAnatomy:nlx_anat_090205 ! Perineurium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9c/Gray636.png/200px-Gray636.png is_a: UBERON:0002384 ! connective tissue relationship: surrounds UBERON:0001019 ! fascicle xref: SCTID:362299001 ! Entire perineurium xref: http://upload.wikimedia.org/wikipedia/commons/9/9c/Gray636.png xref: UMLS:C0205890 [Term] id: UBERON:0000123 ! endoneurium name: endoneurium def: "a layer of delicate connective tissue that encloses the myelin sheath of a nerve fiber within a funiculus." [Wikipedia:Endodeurium] xref: FMA:52586 ! Endoneurium xref: NIF_GrossAnatomy:nlx_anat_090202 ! Endoneurium is_a: UBERON:0002384 ! connective tissue relationship: surrounds UBERON:0001021 ! nerve relationship: surrounds GO:0043209 ! myelin sheath xref: ncithesaurus:Endoneurium ! Endoneurium xref: SCTID:15931004 ! Endoneurium xref: UMLS:C0205888 [Term] id: UBERON:0000124 name: epineurium def: "outermost layer of connective tissue surrounding a peripheral nerve. It includes the blood vessels supplying the nerve. It consists of adipose tissue and fibrocollagenous tissues." [Wikipedia:Epineurium] xref: FMA:12234 ! Epineurium xref: ncithesaurus:Epineurium ! Epineurium xref: BTO:0003154 ! epineurium xref: NIF_GrossAnatomy:nlx_anat_090203 ! Epineurium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9c/Gray636.png/200px-Gray636.png is_a: UBERON:0002384 ! connective tissue relationship: surrounds UBERON:0002003 ! peripheral nerve xref: SCTID:64482002 ! Epineurium xref: http://upload.wikimedia.org/wikipedia/commons/9/9c/Gray636.png xref: UMLS:C0205889 [Term] id: UBERON:0000126 name: cranial nerve nucleus def: "collection of neurons (gray matter) in the brain stem that is associated with one or more cranial nerves." [Wikipedia:Cranial_nerve_nucleus] synonym: "nucleus of cranial nerve" EXACT [] synonym: "cranial neural nucleus" EXACT [FMA:54501] xref: FMA:54501 ! Nucleus of cranial nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: overlaps UBERON:0001785 ! cranial nerve xref: SCTID:280160003 ! Entire cranial nerve nucleus synonym: "nucleus nervi cranialis" RELATED LATIN [Wikipedia:Cranial_nerve_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png [Term] id: UBERON:0011775 ! vagus nerve nucleus name: vagus nerve nucleus synonym: "nucleus of vagal X nerve" EXACT [] synonym: "nucleus of vagal nerve" EXACT [] synonym: "nucleus of vagus nerve" EXACT [FMA:54573] synonym: "tenth cranial nerve nucleus" EXACT [FMA:54573] intersection_of: UBERON:0000126 ! cranial nerve nucleus intersection_of: overlaps UBERON:0001759 ! vagus nerve relationship: part_of UBERON:0002028 ! hindbrain xref: FMA:54573 ! vagus nerve nucleus xref: SCTID:362467005 ! Entire vagus nerve nucleus def: "A cranial nerve nucleus that overlaps a vagus nerve." [OBOL:automatic] [Term] id: UBERON:0011778 ! motor nucleus of vagal nerve name: motor nucleus of vagal nerve comment: Usage notes: in ZFA this is the superclass of dorsolateral and medial (which have not been generalized above ZFA). In this ontology it is a broad grouping class covering these zebrafish structures as well as the generalized dorsal motor nucleus synonym: "motor nucleus X" EXACT [ZFA:0000387] synonym: "nX" BROAD [ZFA:0000387] synonym: "nucleus motorius of nervi vagi" EXACT LATIN [ZFA:0000387] synonym: "vagal lobe" RELATED [ZFA:0000387] is_a: UBERON:0011775 ! vagus nerve nucleus xref: ZFA:0000387 ! motor nucleus of vagal nerve [Term] id: UBERON:0010127 name: future dorsal motor nucleus of vagus is_a: UBERON:0000125 {source="EHDAA2"} ! neural nucleus intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: develops_into UBERON:0002870 ! dorsal motor nucleus of vagus nerve xref: EHDAA2:0004650 ! future dorsal motor nucleus of vagus def: "A gray matter of neuraxis that develops_into a dorsal motor nucleus of vagus nerve." [OBOL:automatic] [Term] id: UBERON:0002870 name: dorsal motor nucleus of vagus nerve def: "The dorsal nucleus of the vagus nerve (or posterior motor nucleus of vagus) is a cranial nerve nucleus for the vagus nerve that arises from the floor of the fourth ventricle. It mostly serves parasympathetic vagal functions in the heart, gastrointestinal tract, lungs, and other thoracic and abdominal vagal innervations. [WP,unvetted]." [Wikipedia:Dorsal_nucleus_of_vagus_nerve] subset: uberon_slim synonym: "dorsal efferent nucleus of vagus" EXACT [FMA:54592] synonym: "dorsal vagal nucleus" EXACT [NIF_GrossAnatomy:birnlex_2642] synonym: "nucleus alaris" EXACT [NIF_GrossAnatomy:birnlex_2642] synonym: "dorsal motor nucleus of vagus X nerve" EXACT [MA:0001036] synonym: "nucleus posterior nervi vagi" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "dorsal nucleus of vagus nerve" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "dorsal motor nucleus of the vagus" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "dorsal motor nucleus of the vagus nerve" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "dorsal motor nucleus of vagus nerve" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "dorsal motor vagal nucleus" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "dorsal nucleus of the vagus nerve" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "dorsal vagal nucleus" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "posterior nucleus of vagus nerve" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] synonym: "vagus nucleus" RELATED [Wikipedia:Dorsal_nucleus_of_vagus_nerve] xref: MA:0001036 ! dorsal motor nucleus of vagus X nerve xref: FMA:54592 ! Dorsal motor nucleus of vagus nerve xref: NIF_GrossAnatomy:birnlex_2642 ! Dorsal motor nucleus of vagus nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/82/Gray697.png/200px-Gray697.png xref: EV:0100287 ! dorsal vagal nucleus xref: ABA:DMX ! Dorsal motor nucleus of the vagus nerve xref: BM:DX ! dorsal vagal nucleus is_a: UBERON:0011778 ! motor nucleus of vagal nerve relationship: part_of UBERON:0001896 {source="NIF", source="MA"} ! medulla oblongata relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus xref: ncithesaurus:Dorsal_Nucleus_of_the_Vagus_Nerve ! Dorsal Nucleus of the Vagus Nerve xref: SCTID:52884007 ! Dorsal motor nucleus of vagus nerve xref: EHDAA2:0004649 ! dorsal motor nucleus of vagus relationship: immediate_transformation_of UBERON:0010127 {evidence="definitional"} ! future dorsal motor nucleus of vagus xref: UMLS:C0926535 [Term] id: UBERON:0000151 name: pectoral fin def: "The paired pectoral fins are located on each side, usually just behind the operculum, and are homologous to the forelimbs of tetrapods." [Wikipedia:Pectoral_fin#Fins] comment: check definition of limb such that is excludes fins. Note the GO includes pectoral and pelvic fins as types of limbs. The Actinopterygii (ray finned fish) pectoral and pelvic fins aren't homologous as fore- or hindlimbs to those of tetrapods, whereas those of the Sarcopterygii (lobe finned fish) are in fact homologous. xref: TAO:0001161 ! pectoral fin xref: ZFA:0001161 ! pectoral fin xref: BTO:0004653 ! pectoral fin xref: VSAO:0000147 ! pectoral fin is_a: UBERON:0004710 {is_entailed="true"} ! pectoral appendage intersection_of: UBERON:0002534 ! paired fin intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: develops_from UBERON:0005419 ! pectoral appendage bud xref: SCTID:416982006 ! Pectoral fin property_value: external_definition "Paired fin that is located in the thoracic region of the body.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001161", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_definition "Paired fin that is located in the thoracic region of the body.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000147", date_retrieved="2012-08-14", source="TAO:curator"} synonym: "forefin" EXACT [VSAO:0000147] synonym: "nageoire pectorale@fr" RELATED [VSAO:0000147] synonym: "omoptcérygie@fr" RELATED [VSAO:0000147] synonym: "thoracoptcérygie@fr" RELATED [VSAO:0000147] [Term] id: UBERON:0000152 name: pelvic fin def: "The paired pelvic or ventral fins are located ventrally below the pectoral fins. They are homologous to the hindlimbs of tetrapods. The pelvic fin assists the fish in going up or down through the water, turning sharply, and stopping quickly." [Wikipedia:Pectoral_fin#Fins] comment: check definition of limb such that is excludes fins. Note the GO includes pectoral and pelvic fins as types of limbs. xref: TAO:0001184 ! pelvic fin xref: ZFA:0001184 ! pelvic fin xref: BTO:0004651 ! pelvic fin xref: EFO:0003644 ! pelvic fin xref: VSAO:0000129 ! pelvic fin is_a: UBERON:0004709 {is_entailed="true"} ! pelvic appendage intersection_of: UBERON:0002534 ! paired fin intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: develops_from UBERON:0005420 ! pelvic appendage bud property_value: external_definition "Paired fin located in the abdominal position of the body.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001184", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_definition "Paired fin located in the abdominal position of the body.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000129", date_retrieved="2012-08-14", source="TAO:curator"} synonym: "nageoire pelvienne@fr" RELATED [VSAO:0000129] synonym: "ischioptcérygie@fr" RELATED [VSAO:0000129] [Term] id: UBERON:0000153 ! anterior region of body name: anterior region of body is_a: UBERON:0000475 ! organism subdivision relationship: anterior_to UBERON:0000154 ! posterior region of body [Term] id: UBERON:0000154 ! posterior region of body name: posterior region of body is_a: UBERON:0000475 ! organism subdivision [Term] id: UBERON:0000155 name: theca cell layer def: "A layer of the ovarian follicles. They appear as the follicles become tertiary follicles. The theca folliculi are responsible for the production of testosterone from androstenedione in females, and indirectly the production of estrogens by supplying the neighboring granulosa cells with androstenedione that can then be used as a substrate for aromatase." [Wikipedia:Theca_of_follicle] subset: vertebrate_core synonym: "layer of theca cells" EXACT [] synonym: "theca cell layer of ovarian follicle" EXACT [] synonym: "theca folliculi" RELATED [] synonym: "theca of follicle" EXACT [] synonym: "thecal cell layer" EXACT [ZFA:0001113] xref: FMA:18656 ! Theca folliculi xref: TAO:0001113 ! thecal cell layer xref: ZFA:0001113 ! thecal cell layer xref: BTO:0002853 ! theca folliculi xref: EFO:0003629 ! thecal cell layer is_a: UBERON:0000119 ! cell layer relationship: has_part CL:0000503 ! theca cell relationship: part_of UBERON:0001305 ! follicle of ovary synonym: "theca folliculi" RELATED LATIN [Wikipedia:Theca_of_follicle] xref: SCTID:361385000 ! Entire theca folliculi [Term] id: UBERON:0000156 name: theca externa alt_id: UBERON:0005182 def: "The theca externa is the outer layers of the theca folliculi. It contains abundant collagen and is mainly supportive." [Wikipedia:Theca_externa] synonym: "ovary theca externa" EXACT [MA:0001713] synonym: "tunica externa of theca folliculi" EXACT [FMA:18657] synonym: "theca externa (folliculus ovaricus tertiarius)" EXACT [FMA:18657] synonym: "external coat of theca folliculi" RELATED [BTO:0002852] synonym: "tunica externa thecae folliculi" RELATED [BTO:0002852] xref: FMA:18657 ! Tunica externa of theca folliculi xref: BTO:0002852 ! theca externa xref: MA:0001713 ! ovary theca externa xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/50/Mature_Graffian_follicle.jpg/200px-Mature_Graffian_follicle.jpg is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0000155 ! theca cell layer relationship: surrounds UBERON:0000157 ! theca interna relationship: has_part GO:0005581 ! collagen xref: SCTID:258767003 ! Entire tunica externa of theca folliculi synonym: "tunica externa thecae folliculi" RELATED LATIN [Wikipedia:Theca_externa] [Term] id: UBERON:0000157 name: theca interna alt_id: UBERON:0005183 def: "Theca interna cells express receptors for luteinizing hormone, which when activated will stimulate the production of androstenedione from cholesterol by the enzyme desmolase. Androstenedione ultimately gives the granulosa cells the precursor substrate for estrogen manufacturing." [Wikipedia:Theca_externa#Theca_interna] synonym: "ovary theca interna" EXACT [MA:0001714] synonym: "tunica interna of theca folliculi" EXACT [FMA:18658] synonym: "theca interna (folliculus ovaricus tertiarius)" EXACT [FMA:18658] synonym: "internal coat of capsule of graafian follicle" RELATED [BTO:0002851] synonym: "tunica interna thecae folliculi" RELATED [BTO:0002851] xref: FMA:18658 ! Tunica interna of theca folliculi xref: BTO:0002851 ! theca interna xref: MA:0001714 ! ovary theca interna is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0000155 ! theca cell layer xref: SCTID:258869006 ! Entire tunica interna of theca folliculi [Term] id: UBERON:0000158 name: membranous layer synonym: "membranous organ component" EXACT [FMA:82500] xref: FMA:82500 ! Membranous layer is_a: UBERON:0004923 ! organ component layer [Term] id: UBERON:0001353 ! anal region name: anal region def: "The anus and surrounding regions. Encompasses both internal and external regions, where present" [UBERON:cjm] subset: uberon_slim xref: EFO:0000847 ! anal region xref: EHDAA:2931 ! anal region xref: VHOG:0000395 ! anal region xref: MA:0000329 ! anal region xref: MAT:0000042 ! anal region xref: MIAA:0000042 ! anal region xref: ncithesaurus:Anal_Region ! Anal Region xref: EHDAA2:0000122 ! anal region xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Gray408.png/200px-Gray408.png xref: EMAPA:16831 ! anal region xref: WBbt:0006919 ! anal region is_a: UBERON:0000477 {source="EHDAA2"} ! anatomical cluster relationship: overlaps UBERON:0006866 ! terminal part of digestive tract relationship: develops_from UBERON:0000931 {evidence="definitional"} ! proctodeum xref: SCTID:362680001 ! Entire anal region property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000395", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0230120 [Term] id: UBERON:0006867 name: anal part of perineum def: "The anal triangle is the posterior part of the perineum. It contains the anal canal. [WP,unvetted]." [Wikipedia:Anal_triangle] synonym: "anal region" BROAD [FMA:20347] synonym: "anal triangle" EXACT [FMA:20347] xref: FMA:20347 ! anal part of perineum is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002356 ! perineum relationship: part_of UBERON:0001353 ! anal region relationship: has_part UBERON:0000159 ! anal canal xref: SCTID:243995004 ! Anal triangle synonym: "regio analis" RELATED LATIN [Wikipedia:Anal_triangle] xref: http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png [Term] id: UBERON:0000159 name: anal canal def: "The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus." [Wikipedia:Anal_canal] comment: Editor notes: requires alignment with EHDAA2 and complete developmental relationships subset: uberon_slim synonym: "anal canal" EXACT [] synonym: "anal canal viewed anatomically" EXACT [] synonym: "anal pad" RELATED [] synonym: "anatomical anal canal" EXACT [] synonym: "anus" RELATED [] synonym: "cloaca" RELATED [] synonym: "cloacal chamber" RELATED [] synonym: "mesenteron" RELATED [] synonym: "canalis analis" RELATED [BTO:0001978] synonym: "pars analis recti" RELATED [BTO:0001978] xref: FMA:15703 ! Anal canal xref: galen:AnalCanal xref: MA:0000330 ! anal canal xref: ncithesaurus:Anal_Canal xref: BTO:0001978 ! anal canal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/17/Gray1078.png/200px-Gray1078.png xref: EMAPA:18256 ! anal canal is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0001353 ! anal region relationship: part_of UBERON:0000059 ! large intestine relationship: continuous_with UBERON:0001052 ! rectum relationship: continuous_with UBERON:0001245 ! anus relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer xref: SCTID:245438008 ! Entire anal canal synonym: "canalis analis" RELATED LATIN [Wikipedia:Anal_canal] xref: http://upload.wikimedia.org/wikipedia/commons/1/17/Gray1078.png xref: UMLS:C0227411 [Term] id: UBERON:0009882 name: anal column def: "One of a number of vertical folds, produced by an infolding of the mucous membrane and some of the muscular tissue in the upper half of the lumen of the anal canal. They are named after Giovanni Battista Morgagni who also has several other eponyms named after himself[WP]" [Wikipedia:Anal_columns] synonym: "column of Morgagni" EXACT [FMA:15713] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000159 ! anal canal xref: FMA:15713 ! anal column xref: SCTID:245444007 ! Entire anal column xref: ncithesaurus:Anal_Column ! Anal Column synonym: "columnae anales" RELATED LATIN [Wikipedia:Anal_columns] xref: http://upload.wikimedia.org/wikipedia/commons/1/17/Gray1078.png xref: UMLS:C0227428 [Term] id: UBERON:0006866 ! terminal part of digestive tract name: terminal part of digestive tract comment: Usage notes: this class is the superclass of 'rectum', which is currently reserved for the vertebrate structure. May be merged in future. synonym: "terminal section of digestive tract" RELATED [] synonym: "rectal part of digestive tract" RELATED [] synonym: "rectum" RELATED [FBbt:00005756] xref: FBbt:00005756 ! rectum xref: WBbt:0005773 ! rectum is_a: UBERON:0004921 ! subdivision of digestive tract relationship: develops_from UBERON:0001046 ! hindgut relationship: continuous_with UBERON:0001245 ! anus [Term] id: UBERON:0001052 name: rectum def: "The terminal portion of the intestine." [Wikipedia:Rectum] comment: Taxon notes: In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html subset: uberon_slim synonym: "terminal portion of intestine" EXACT [] synonym: "terminal portion of large intestine" RELATED [] synonym: "rectal sac" RELATED [] synonym: "intestinum rectum" RELATED [BTO:0001158] xref: BTO:0001158 xref: EFO:0000848 ! rectum xref: EHDAA:5836 ! rectum xref: FMA:14544 ! Rectum xref: GAID:311 ! rectum xref: VHOG:0000427 ! rectum xref: MA:0000336 ! rectum xref: MAT:0000050 ! rectum xref: MIAA:0000050 ! rectum xref: ncithesaurus:Rectum xref: OpenCyc:Mx4rvVjaU5wpEbGdrcN5Y29ycA xref: XAO:0000238 ! rectum xref: galen:Rectum ! rectum xref: OpenCyc:Mx4rvVjaU5wpEbGdrcN5Y29ycA ! rectum xref: EHDAA2:0001592 ! rectum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/75/Anorectum.gif/200px-Anorectum.gif xref: EMAPA:17896 ! rectum of hindgut xref: EMAPA:18925 ! rectum of gut xref: MESH:A03.492.411.495.767 ! rectum xref: EV:0100081 ! rectum xref: VHOG:0001751 ! rectum is_a: UBERON:0004921 {source="cjm", order="4"} ! subdivision of digestive tract relationship: distal_part_of UBERON:0000059 {source="Kardong"} ! large intestine relationship: part_of UBERON:0006866 ! terminal part of digestive tract relationship: part_of UBERON:0000059 {source="MA"} ! large intestine relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region relationship: continuous_with UBERON:0001159 ! sigmoid colon xref: AAO:0010401 ! rectum xref: SCTID:181261002 ! Entire rectum xref: http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif property_value: external_definition "The terminal portion of the large intestine between the ileo-pelvic colon and the anus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001751", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "rectal" xsd:string xref: UMLS:C0034896 [Term] id: UBERON:0012465 ! lumen of terminal part of digestive tract name: lumen of terminal part of digestive tract comment: includes the cloacal lumen, in species where this is present intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0006866 ! terminal part of digestive tract relationship: part_of UBERON:0006866 ! terminal part of digestive tract [Term] id: UBERON:0009670 name: rectal lumen def: "An anatomical space that surrounded_by a rectum." [OBOL:automatic] synonym: "lumen of rectum" EXACT [FMA:14598] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0012465 {source="cjm"} ! lumen of terminal part of digestive tract relationship: develops_in UBERON:0009669 {source="EHDAA2"} ! embryonic cloacal lumen xref: EHDAA2:0004587 ! rectal lumen xref: FMA:14598 ! lumen of rectum xref: SCTID:259740004 ! Entire rectal lumen [Term] id: UBERON:0000160 name: intestine def: "Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." [GOC:GO, Wikipedia:Intestine] comment: MA also has a class MA:0001524 bowel, not clear how this is different. Usage notes: this class is currently very general, encompassing the C elegans 'intestine', which is a tube of epithelial cells extending from the 'pharynx' to 'rectum'. Taxon notes: [in zebrafish] No stomach, small intestine, or large intestine can be distinguished. However, differences can be found in the morphology of the mucosa columnar epithelial cells and the number of goblet cells, suggesting functional differentiation. The intestine has numerous folds that become progressively shorter in a rostral-to-caudal direction. Proportionally, these folds are significantly larger than the finger-like intestinal villi of mammals and other amniotes (Wallace et al. 2005). Columnar-shaped absorptive enterocytes are the most numerous in the zebrafish intestinal epithelium. Goblet cells are the second most populous epithelial cell type. subset: uberon_slim subset: vertebrate_core synonym: "bowel" EXACT [] xref: BTO:0000648 xref: EFO:0000834 ! intestine xref: FMA:7199 ! Intestine xref: galen:Intestine xref: VHOG:0000056 ! intestine xref: MA:0000328 ! intestine xref: MA:0001524 ! bowel xref: MIAA:0000043 ! intestine xref: TAO:0001338 ! intestine xref: WBbt:0005772 ! intestine xref: XAO:0000129 ! intestine xref: ZFA:0001338 ! intestine xref: ncithesaurus:Intestine ! Intestine xref: GAID:295 ! intestine xref: AAO:0000246 ! intestines xref: MESH:A03.492.411 ! intestine xref: EV:0100071 ! intestine xref: ANISEED:1235303 ! Intestine is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract relationship: part_of UBERON:0005409 ! gastrointestinal system xref: SCTID:256876008 ! Entire intestine property_value: external_definition "Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000246", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "The tract of the alimentary canal. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000056", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "intestinal" xsd:string xref: UMLS:C0021853 [Term] id: UBERON:0000161 ! orifice name: orifice def: "Anatomical conduit that connects two adjacent body spaces, surrounded by two or more subdivisions of two or more organs. Examples: right atrioventricular orifice, orifice of artery, hilum of kidney, porta hepatis[FMA,modified]." [FMA:3724] comment: in FMA, this is an anatomical conduit *space*, rather than anatomical conduit subset: upper_ontology_conflict synonym: "anatomical orifice" EXACT [FMA:3724] synonym: "hilum" NARROW [] synonym: "anatomical ostium" EXACT [FMA:3724] xref: FMA:3724 ! Anatomical orifice is_a: UBERON:0004111 ! anatomical conduit xref: SCTID:91837002 ! Anatomical orifice [Term] id: UBERON:0012361 name: internal anal region is_a: UBERON:0000477 {source="EHDAA2"} ! anatomical cluster relationship: part_of UBERON:0001353 {source="EHDAA2"} ! anal region xref: EHDAA2:0004588 ! internal anal region [Term] id: UBERON:0012469 name: external anal region is_a: UBERON:0000477 {source="EHDAA2"} ! anatomical cluster relationship: part_of UBERON:0001353 {source="EHDAA2"} ! anal region xref: EHDAA2:0004589 ! external anal region [Term] id: UBERON:0011510 ! cloacal bursa name: cloacal bursa is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000162 ! cloaca relationship: has_function_in GO:0007585 {gci_relation="part_of", gci_filler="NCBITaxon:8459", notes="cloacal bursa"} ! respiratory gaseous exchange [Term] id: UBERON:0012420 name: coprodeum def: "Most proximal cloacal compartment, into which the large intestine empties[Kardong]" [ISBN10:0073040584] synonym: "coprodeal portion of cloaca" EXACT [] synonym: "coprodaeum" EXACT [] synonym: "cloacal coprodeum" EXACT [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000162 ! cloaca relationship: proximal_part_of UBERON:0000162 ! cloaca property_value: has_relational_adjective "coprodeal" xsd:string [Term] id: UBERON:0012421 name: urodeum def: "Cloacal compartment into which the urogenital system empties[Kardong]" [ISBN10:0073040584] comment: Taxon notes: This is where the urates collect. In the hen the oviduct opens into this compartment.[http://caiquesite.com/glossary.htm] synonym: "urodeal portion of cloaca" EXACT [] synonym: "urodaeum" EXACT [] synonym: "cloacal urodeum" EXACT [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000162 ! cloaca xref: SCTID:81191004 ! Urodeum property_value: has_relational_adjective "urodeal" xsd:string [Term] id: UBERON:0012462 name: proctodeum portion of cloaca def: "Most distal cloacal compartment; function is copulation and in some species develops a penis[Kardong]" [ISBN10:0073040584] comment: Taxon notes: For most birds this is where the phallus is located, but male parrots do not have a phallus. The Bursa of Fabricus is located here.[http://caiquesite.com/glossary.htm] synonym: "proctodeum" RELATED INCONSISTENT [] synonym: "proctodeal wall of cloaca" RELATED [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000162 ! cloaca relationship: distal_part_of UBERON:0000162 ! cloaca xref: SCTID:298233001 ! Entire proctodeum property_value: has_relational_adjective "proctodeal" xsd:string [Term] id: UBERON:0000162 ! cloaca name: cloaca def: "Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures" [Wikipedia:Cloaca, ISBN10:0073040584] comment: Development notes: hindgut endoderm and proctodeal ectoderm. Taxon notes: Human beings only have an embryonic cloaca, which is split up into separate tracts during the development of the urinary and reproductive organs[WP]. Editor notes: adding df link to embryonic cloaca leads to a cycle in uberon-simple, as cloaca is a suberclass of embryonic cloaca synonym: "vent" RELATED [XAO:0000244] synonym: "cloacal chamber" RELATED [AAO:0000095] xref: VHOG:0001186 ! cloaca xref: AAO:0000095 ! cloaca xref: XAO:0000244 ! cloaca xref: ncithesaurus:Cloaca ! Cloaca xref: GAID:1206 ! cloaca xref: MESH:A13.223 ! cloaca xref: SCTID:362857006 ! Entire cloaca is_a: UBERON:0000481 {source="AAO"} ! multi-tissue structure relationship: part_of UBERON:0004122 {source="AAO"} ! genitourinary system relationship: part_of UBERON:0001555 {source="ZFA"} ! digestive tract relationship: present_in_taxon NCBITaxon:9369 {notes="most adult placentals have no trace of a cloaca. However, the tenrecs and golden moles, small placental mammals native to Africa, retain a cloaca as adults."} ! Tenrecidae property_value: external_definition "Anatomical structure which is the common receptacle for the alimentary canal, Wolffian ducts, oviducts, and the bladder.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000095", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "A common passage for fecal, urinary, and reproductive discharge in most lower vertebrates as well as the terminal end of the hindgut before division into rectum, bladder, and genital primordia in mammalian embryos. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001186", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/cloaca", source="http://bgee.unil.ch/"} property_value: homology_notes "A cloaca is apparently a primitive vertebrate feature because it occurs in most primitive gnathostomes and persists in the embryos of almost all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0001186", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.572", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "cloacal" xsd:string xref: UMLS:C0008987 [Term] id: UBERON:0012463 name: cloacal lumen synonym: "cloacal chamber" EXACT [ZFA:0000330] comment: the ZFA class belongs here as it is an anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0012465 {source="cjm"} ! lumen of terminal part of digestive tract xref: ZFA:0000330 ! cloacal chamber xref: TAO:0000330 ! cloacal chamber [Term] id: UBERON:0012464 name: cloacal vent synonym: "vent" RELATED [] synonym: "cloacal orifice" RELATED [] synonym: "cloacal opening" EXACT [] intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012478 name: cloacal gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012479 name: urodeal gland synonym: "urodaeal gland" EXACT [] intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0012421 ! urodeum [Term] id: UBERON:0000163 ! embryonic cloaca name: embryonic cloaca def: "endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]." [Wikipedia:Cloaca_(embryology), MP:0010115] comment: compare UBERON:0000162 cloaca synonym: "cloaca" RELATED SENSU [] xref: EHDAA:4895 ! cloaca xref: EHDAA2:0000256 ! cloaca xref: EMAPA:27573 ! cloaca of genitourinary system xref: EMAPA:27638 ! cloaca of urinary system is_a: UBERON:0000162 ! cloaca relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001008 {source="EHDAA2"} ! excretory system relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region relationship: has_developmental_contribution_from UBERON:0003064 ! intermediate mesoderm [Term] id: UBERON:0006217 name: cloacal membrane def: "the membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings." [Wikipedia:Cloacal_membrane, MP:anna, MP:0011837] subset: emapa_ehdaa2 xref: EMAPA:16832 ! cloacal membrane xref: EHDAA2:0000257 ! cloacal membrane xref: VHOG:0001198 ! cloacal membrane xref: EHDAA:2933 ! cloacal membrane of anal region xref: EHDAA:214 ! cloacal membrane is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0000163 ! embryonic cloaca relationship: develops_from UBERON:0004341 {source="Wikipedia"} ! primitive streak relationship: has_developmental_contribution_from UBERON:0000924 ! ectoderm relationship: has_developmental_contribution_from UBERON:0000925 ! endoderm xref: ncithesaurus:Cloacal_Membrane ! Cloacal Membrane xref: SCTID:308826008 ! Entire cloacal membrane synonym: "embryonic cloacal membrane" EXACT [] synonym: "membrana cloacalis" RELATED LATIN [Wikipedia:Cloacal_membrane] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png property_value: external_definition "A membrane that separates the proctodeum and the hindgut in the early embryo. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.497, see_Kardong_KV][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001198", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In mammals, the cloaca exists as an embryonic structure that undergoes septation to become distinct urethral, anal, and genital orifices.[well established][VHOG]" xsd:string {external_class="VHOG:0001198", ontology="VHOG", source="PMID:11830557 De Santa Barbara P\, Roberts DJ\, Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13. Development (2002)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231056 [Term] id: UBERON:0009846 name: embryonic cloacal epithelium is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000163 ! embryonic cloaca relationship: part_of UBERON:0003929 {source="EHDAA2"} ! gut epithelium relationship: develops_from UBERON:0003353 {source="EHDAA2"} ! epithelium of hindgut xref: EHDAA2:0004585 ! cloacal epithelium synonym: "cloacal epithelium" BROAD [EHDAA2:0004585] def: "An epithelium that is part of a embryonic cloaca." [OBOL:automatic] [Term] id: UBERON:0009669 name: embryonic cloacal lumen intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0000163 ! embryonic cloaca relationship: part_of UBERON:0000163 ! embryonic cloaca relationship: surrounded_by UBERON:0009846 ! embryonic cloacal epithelium xref: EHDAA2:0004586 ! cloacal lumen def: "An anatomical space that surrounded_by a embryonic cloaca." [OBOL:automatic] [Term] id: UBERON:0009844 name: urogenital sinus lumen intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0000164 ! primitive urogenital sinus relationship: develops_in UBERON:0009669 {source="EHDAA2"} ! embryonic cloacal lumen relationship: surrounded_by UBERON:0004902 ! urogenital sinus epithelium xref: EHDAA2:0002142 ! urogenital sinus lumen def: "An anatomical space that surrounded_by a primitive urogenital sinus." [OBOL:automatic] [Term] id: UBERON:0000164 name: primitive urogenital sinus def: "Ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females[MP]." [Wikipedia:Definitive_urogenital_sinus] comment: Note that the term "urogenital sinus" may refer to the primitive urogenital sinus present as a transient developmental structure in most mammals or it may refer to a condition in which an unseptated cloaca persists in animals longer than normal[MP] synonym: "sinus urogenitalis" EXACT LATIN [] synonym: "urogenital sinus" BROAD [MP:0010116] synonym: "UGS" EXACT [MP:0010116] synonym: "fetal UGS" EXACT [PMID:18977204] xref: VHOG:0000414 ! urogenital sinus xref: ncithesaurus:Urogenital_Sinus ! Urogenital Sinus xref: EHDAA:5029 ! urogenital sinus xref: EHDAA:5919 ! urogenital sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Gray1109.png/200px-Gray1109.png xref: EMAPA:17211 ! urogenital sinus of genitourinary system xref: EMAPA:17379 ! urogenital sinus of urinary system is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0001008 {source="EHDAA2"} ! excretory system relationship: part_of UBERON:0000163 {source="MP-def"} ! embryonic cloaca relationship: develops_from UBERON:0003064 ! intermediate mesoderm xref: EHDAA2:0004060 ! urogenital sinus xref: SCTID:50961009 ! Urogenital sinus xref: http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png property_value: external_definition "The ventral part of the cloaca after its separation from the rectum, giving rise to the lower part of the bladder in both sexes, to the prostatic portion of the male urethra, and to the urethra and vestibule in the female. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000414", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/urogenital+sinus", source="http://bgee.unil.ch/"} property_value: homology_notes "In mammals the lowly monotremes still have a cloaca. Higher types have done away with this structure and have a separate anal outlet for the rectum. The monotreme cloaca shows the initiation of this subdivision. The cloaca has such includes only the distal part, roughly comparable to the proctodeum. The more proximal part is divided into (1) a large dorsal passage into which the intestine opens, the coprodeum, and (2) a ventral portion, the urodeum with which the bladder connects. (...) the development of the placental mammals recapitulates in many respects the phylogenetic story. In the sexually indifferent stage of placental mammal there is a cloaca. While the indifferent stage still persists, a septum develops, and extends out to the closing membrane. This divides the cloaca into two chambers: a coprodeum continuous with the gut above, and a urodeum or urogenital sinus below.[well established][VHOG]" xsd:string {external_class="VHOG:0000414", ontology="VHOG", source="ISBN:978-0721676678 Romer AS\, Vertebrate body (1970)p.388-89 and Figure 300", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231057 [Term] id: UBERON:0004902 name: urogenital sinus epithelium def: "The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra" [PMID:18977204] comment: we follow EHDAA2 in dividing the UGS into epithelium and lumen synonym: "UGE" EXACT [PMID:18977204] synonym: "epithelium of urogenital sinus" EXACT [OBOL:automatic] is_a: UBERON:0000483 {source="PMID:18977204"} ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000164 ! urogenital sinus relationship: develops_from UBERON:0009846 {source="EHDAA2"} ! embryonic cloacal epithelium xref: EHDAA2:0004061 ! urogenital sinus epithelium [Term] id: UBERON:0009845 ! urogenital sinus mesenchyme name: urogenital sinus mesenchyme def: "Mesenchyme that surrounds primitive urogenital sinus." [OBOL:automatic] comment: Androgen receptor (AR) activation releases instructive signals from UGM that acts on UGS epithelium (UGE) to stimulate cell proliferation, form prostate ductal progenitors (prostatic buds), and regulate cell adhesion dynamics to permit prostatic bud outgrowth synonym: "UGM" EXACT ABBREVIATION [PMID:18977204] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: surrounds UBERON:0000164 {source="PMID:18977204"} ! primitive urogenital sinus [Term] id: UBERON:0000168 name: segment of colon def: "An organ segment that is part of a colon [Automatically generated definition]." [OBOL:automatic] xref: FMA:222905 ! Segment of colon is_a: UBERON:0004921 {source="cjm", order="4"} ! subdivision of digestive tract intersection_of: UBERON:0000063 ! organ segment intersection_of: part_of UBERON:0001155 ! colon [Term] id: UBERON:0000170 ! pair of lungs name: pair of lungs synonym: "lungs" EXACT [] synonym: "lungs pair" EXACT [] synonym: "set of lungs" EXACT [] xref: FMA:68877 ! Pair of lungs xref: OpenCyc:Mx4rvVjKy5wpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvVjKy5wpEbGdrcN5Y29ycA ! lung is_a: UBERON:0000477 ! anatomical cluster relationship: has_part UBERON:0002167 ! right lung relationship: has_part UBERON:0002168 ! left lung relationship: part_of UBERON:0001558 {source="FMA-abduced"} ! lower respiratory tract relationship: located_in UBERON:0002224 ! thoracic cavity synonym: "pulmones" EXACT LATIN [FMA:TA, FMA:68877] [Term] id: UBERON:0000171 name: respiration organ def: "Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [GO:0007585] subset: functional_classification synonym: "breathing organ" EXACT [] synonym: "gas exchange organ" RELATED [] synonym: "respiratory organ" EXACT [] synonym: "apparatus respiratorius organ" EXACT [OBOL:automatic] synonym: "organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "organ of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system organ" EXACT [OBOL:automatic] xref: TGMA:0001247 ! spiracular apparatus xref: EMAPA:17607 ! respiratory xref: SPD:0000428 ! booklung intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange relationship: part_of UBERON:0001004 ! respiratory system xref: SCTID:272626006 ! Respiratory organ subset: organ_slim [Term] id: UBERON:0000172 name: vomit def: "Vomit is a bodily fluid consisting of the expulsed contents of the stomach of an organism disgorged through the mouth or nose." [ENVO:00000338] xref: ENVO:00000338 xref: OpenCyc:Mx4rvViQTJwpEbGdrcN5Y29ycA xref: galen:Vomitus ! vomitus xref: ncithesaurus:Vomitus ! vomitus xref: OpenCyc:Mx4rvViQTJwpEbGdrcN5Y29ycA ! vomit is_a: UBERON:0000463 ! portion of organism substance [Term] id: UBERON:0000173 name: amniotic fluid def: "Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided." [ENVO:02000021] synonym: "acqua amnii" RELATED [BTO:0000068] synonym: "liquor amnii" RELATED [BTO:0000068] xref: BTO:0000068 xref: ENVO:02000021 xref: VHOG:0001267 ! amniotic fluid xref: MA:0002893 ! amniotic fluid xref: ncithesaurus:Amniotic_Fluid ! Amniotic Fluid xref: GAID:1155 ! amniotic fluid xref: MESH:A12.098 ! amniotic fluid xref: EV:0100123 ! amniotic fluid is_a: UBERON:0000463 ! portion of organism substance relationship: surrounds UBERON:0000922 ! embryo xref: UMLS:C0002638 [Term] id: UBERON:0000174 ! excreta name: excreta alt_id: UBERON:0000324 alt_id: UBERON:0007550 def: "Excreta are bodily fluids consisting of waste matter, such as sweat or feces, discharged from the body." [ENVO:02000022] synonym: "excreted substance" EXACT [] synonym: "excretion" RELATED [BTO:0000491] synonym: "waste substance" EXACT [AEO:0000184] synonym: "waste substance" EXACT [AEO:0000184] xref: BTO:0000491 ! excretion xref: ENVO:02000022 xref: FMA:9674 ! Excretion xref: galen:Excretion xref: AEO:0000184 ! waste substance xref: EHDAA2:0003184 is_a: UBERON:0000463 ! portion of organism substance relationship: output_of GO:0007588 ! excretion [Term] id: UBERON:0007780 name: exudate def: "Exudates are fluids, cells, or other cellular substances that are slowly discharged from blood vessels usually from inflamed tissues." [MESH:A12.383] synonym: "transudates and exudate" RELATED [GAID:1195] xref: MESH:A12.383 ! (also: UBERON:0007779 'transudate') is_a: UBERON:0000463 ! portion of organism substance xref: ncithesaurus:Exudate ! Exudate [Term] id: UBERON:0000177 name: pus def: "Pus is a bodily fluid consisting of a whitish-yellow or yellow substance produced during inflammatory responses of the body that can be found in regions of pyogenic bacterial infections. Pus is produced from the dead and living cells which travel into the intercellular spaces around the affected cells." [ENVO:02000038, Wikipedia:Pus] comment: AO notes: biospecimen in NCIT synonym: "purulent exudate" RELATED [] xref: ENVO:02000038 xref: OpenCyc:Mx4rvVjG6ZwpEbGdrcN5Y29ycA xref: ncithesaurus:Pus ! Pus xref: galen:Pus ! pus xref: OpenCyc:Mx4rvVjG6ZwpEbGdrcN5Y29ycA ! pus is_a: UBERON:0000463 ! portion of organism substance relationship: has_function_in GO:0006954 ! inflammatory response xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/90/Swollen_eye_with_conjunctivitis.jpg/180px-Swollen_eye_with_conjunctivitis.jpg [Term] id: UBERON:0000178 name: blood def: "Circulating body substance which consists of blood plasma and hemoglobin-carrying red blood cells. Excludes blood analogues (see UBERON:0000179 haemolymphatic fluid)." [FMA:9670, Wikipedia:Blood] subset: uberon_slim subset: vertebrate_core synonym: "vertebrate blood" EXACT [] synonym: "portion of blood" EXACT [] synonym: "whole blood" RELATED [BTO:0000089] xref: BTO:0000089 xref: EFO:0000296 ! blood xref: ENVO:02000027 xref: FMA:9670 ! Portion of blood xref: galen:Blood xref: VHOG:0000224 ! blood xref: MA:0000059 ! blood xref: MIAA:0000315 ! blood xref: OpenCyc:Mx4rvVjI8JwpEbGdrcN5Y29ycA xref: TAO:0000007 ! blood xref: XAO:0000124 ! blood xref: ZFA:0000007 ! blood xref: ncithesaurus:Blood ! Blood xref: GAID:965 ! blood xref: EHDAA:418 ! blood xref: OpenCyc:Mx4rvVjI8JwpEbGdrcN5Y29ycA ! blood xref: AAO:0000046 ! blood xref: EHDAA2:0000176 ! blood xref: EMAPA:16332 ! blood xref: MESH:A12.207.152 ! blood xref: EV:0100047 ! blood is_a: UBERON:0000179 ! haemolymphatic fluid relationship: has_part CL:0000232 ! erythrocyte relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0004535 ! cardiovascular system property_value: external_definition "Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000046", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000046", date_retrieved="2012-06-20"} property_value: external_definition "A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000007", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG]" xsd:string {external_class="VHOG:0000224", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V\, Blood cells and blood cell development in the animal kingdom. Annual review of cell and developmental biology (2006) ", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0005767 [Term] id: UBERON:0000179 name: haemolymphatic fluid def: "Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs." [] synonym: "blood or blood analog" RELATED [] is_a: UBERON:0000463 ! portion of organism substance intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: part_of UBERON:0002390 ! hematopoietic system created_by: cjm creation_date: 2009-04-08T04:38:19Z [Term] id: UBERON:0000200 name: gyrus def: "A ridge, generally surrounded by one or more sulci." [Wikipedia:Gyrus] synonym: "gyrus of neuraxis" EXACT [FMA:83874] synonym: "cerebral gyrus" EXACT [BTO:0002495] synonym: "gyri of cerebrum" RELATED PLURAL [BTO:0002495] synonym: "gyri" RELATED PLURAL [BTO:0002495] synonym: "gyrus of cerebrum" RELATED [BTO:0002495] xref: BTO:0002495 ! cerebral gyrus xref: FMA:83874 ! gyrus of neuraxis is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001869 ! cerebral hemisphere relationship: surrounded_by UBERON:0000093 ! sulcus xref: ncithesaurus:Cerebral_Gyrus ! Cerebral Gyrus xref: SCTID:279165009 ! Structure of cerebral gyrus synonym: "neuraxis gyrus" EXACT [FMA:83874] xref: UMLS:C0458308 [Term] id: UBERON:0000201 name: endothelial blood brain barrier def: "A blood brain barrier that is composed of endothelial cells." [UBERON:cjm] xref: NIF_Subcellular:nlx_subcell_100205 ! Blood brain barrier is_a: UBERON:0000120 ! blood brain barrier intersection_of: UBERON:0000120 ! blood brain barrier intersection_of: has_part CL:0000115 ! endothelial cell relationship: has_part UBERON:0001986 ! endothelium created_by: cjm creation_date: 2009-04-10T08:15:44Z [Term] id: UBERON:0000202 name: glial blood brain barrier def: "A blood brain barrier composed of glial cells." [UBERON:cjm] xref: FBbt:00007091 ! sub-perineurial glial sheath is_a: UBERON:0000120 ! blood brain barrier intersection_of: UBERON:0000120 ! blood brain barrier intersection_of: has_part CL:0000124 ! glial cell relationship: has_part CL:0000124 ! glial cell created_by: cjm creation_date: 2009-04-10T08:42:24Z [Term] id: UBERON:0001950 name: neocortex def: "The neocortex is a part of the brain of mammals. It is the outer layer of the cerebral hemispheres, and made up of six layers, labelled I to VI (with VI being the innermost and I being the outermost). The neocortex is part of the cerebral cortex (along with the archicortex and paleocortex, which are cortical parts of the limbic system). It is involved in higher functions such as sensory perception, generation of motor commands, spatial reasoning, conscious thought and, in humans, language. Other names for the neocortex include neopallium and isocortex ('equal rind'). [WP,unvetted]." [Wikipedia:Neocortex, Wikipedia:Neocortex] subset: uberon_slim synonym: "cerebral neocortex" EXACT [] synonym: "homogenetic cortex" EXACT DEPRECATED [ISBN10:0471888893] synonym: "isocortex (sensu lato)" EXACT [FMA:62429] synonym: "isocortex" EXACT [] synonym: "neopallial cortex" EXACT [] synonym: "neopallium" EXACT [] synonym: "homotypical cortex" EXACT [NIF_GrossAnatomy:birnlex_2547] synonym: "nonolfactory cortex" RELATED [BTO:0000920] xref: BTO:0000920 xref: FMA:62429 ! Neocortex xref: GAID:677 ! neocortex xref: MA:0002754 ! neocortex xref: NIF_GrossAnatomy:birnlex_2547 ! Neocortex xref: MESH:A08.186.211.730.885.213.420 ! neocortex xref: ABA:Isocortex ! Isocortex xref: EHDAA2:0004662 ! neopallium is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: spatially_disjoint_from UBERON:0002421 {source="ABA"} ! hippocampal formation relationship: spatially_disjoint_from UBERON:0002264 {source="ABA"} ! olfactory bulb xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Neocortex.jpg [Term] id: UBERON:0000204 name: ventral part of telencephalon def: "Dorsal part (base region) of the telencephalon." [ISBN10:0471888893, GO:0021544, GO_REF:0000021, PMID:12626695] comment: AO notes: BTO term refers specifically to the avian structure subset: developmental_classification synonym: "subpallium" EXACT [ZFA:0000304, GO:0021544] synonym: "subpallium" NARROW [BTO:0003401] synonym: "area ventralis telencephali" EXACT [ZFA:0000304] synonym: "ventral telencephalon" EXACT [ZFA:0000304] xref: ZFA:0000304 ! ventral telencephalon xref: EFO:0003522 ! ventral telencephalon xref: BTO:0003401 ! subpallium is_a: UBERON:0000481 ! multitissue structure relationship: part_of UBERON:0001893 ! telencephalon relationship: adjacent_to UBERON:0000203 ! pallium created_by: cjm creation_date: 2009-04-18T12:12:27Z xref: TAO:0000304 ! ventral telencephalon [Term] id: UBERON:0000203 ! pallium name: pallium def: "Dorsal part (roof region) of the telencephalon[GO]." [ISBN10:0471888893, GO:0021543, Wikipedia:Pallium_(neuroanatomy), https://sourceforge.net/tracker/?func=detail&aid=3535324&group_id=76834&atid=994726] comment: Taxon notes: In humans the cerebrum has three parts: the archipallium, the paleopallium and the neopallium. The developing telencephalon or forebrain is divided into pallium and subpallium. In amphibians, the cerebrum includes archipallium, paleopallium and some of the basal nuclei. Reptiles first developed a neopallium, which continued to develop in the brains of more recent species to become the neocortex of humans and Old World monkeys. In fish, the archipallium is the largest part of the cerebrum. Some researchers suggest the early archipallium gave rise to the human hippocampus[WP] synonym: "area dorsalis telencephali" EXACT [ZFA:0000505] synonym: "dorsal telencephalic area" EXACT [ZFA:0000505] synonym: "dorsal part of telencephalon" EXACT [ISBN10:0471888893] synonym: "dorsal telencephalon" EXACT [ZFA:0000505] subset: developmental_classification xref: SCTID:369224000 ! Entire pallium xref: TAO:0007007 ! pallium xref: TAO:0000505 ! dorsal telencephalon xref: ZFA:0000505 ! dorsal telencephalon is_a: UBERON:0002020 {source="ZFA"} ! gray matter of neuraxis relationship: part_of UBERON:0001893 ! telencephalon created_by: cjm creation_date: 2009-04-18T12:03:09Z property_value: external_definition "The mantle of gray matter forming the cerebral cortex. http://www.thefreedictionary.com/pallium[TAO]" xsd:string {ontology="TAO", external_class="TAO:0007007", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: EFO:0003534 ! dorsal telencephalon [Term] id: UBERON:0007333 name: avian pallium def: "In the anatomy of animals, an avian pallium is the dorsal telencephalon of a bird's brain. Pallium of avian species tend to be relatively large, comprising ~75% of the telencephalic volume." [Wikipedia:Avian_pallium] xref: BTO:0003399 ! avian pallium is_a: UBERON:0000203 ! pallium relationship: part_of UBERON:0001893 ! telencephalon relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0007334 name: nidopallium def: "The nidopallium, meaning nested pallium, is the region of the avian brain that is used mostly for some types of executive functions but also other higher cognitive tasks. The region was renamed to nidopallium in 2002 during the Avian Brain Nomenclature Consortium because the prior name suggested that the region was used for more primitive functions." [Wikipedia:Nidopallium, http://en.wikipedia.org/wiki/Avian_Brain_Nomenclature_Consortium] synonym: "nested pallium" RELATED [BTO:0003389] xref: BTO:0003389 ! nidopallium is_a: UBERON:0000481 ! multitissue structure relationship: part_of UBERON:0007333 ! avian pallium [Term] id: UBERON:0007347 name: hyperpallium def: "Birds have a unique pallial structure known as the hyperpallium, once called the hyperstriatum." [Wikipedia:Hyperpallium] synonym: "hyperstriatum" RELATED [BTO:0003400] xref: BTO:0003400 ! hyperpallium is_a: UBERON:0000481 ! multitissue structure relationship: part_of UBERON:0007333 ! avian pallium [Term] id: UBERON:0007349 name: mesopallium synonym: "middle pallium" RELATED [BTO:0003405] xref: BTO:0003405 ! mesopallium is_a: UBERON:0000481 ! multitissue structure relationship: part_of UBERON:0007333 ! avian pallium [Term] id: UBERON:0007350 name: arcopallium def: "The arcopallium refers to regions of the avian brain which partially overlap regions homologous to the amygdala of mammals. These regions have formerly been referred to as archistriatum, and before this epistriatum or amygdaloid complex[1], and a recent change of nomenclature has divided the region into the arcopallium and posterior pallial amygdala.[2] The new nomenclature, adopted in 2004, reflects a modern understanding that the avian brain is broadly similar to the mammalian brain, containing large regions homologous to the mammalian neocortex, claustrum, and pallial amygdala. The outdated nomenclature it replaced perceived the avian brain as consisting almost entirely of enlarged basal ganglia, to which more complex outer layers had been added during a progress toward mammalian intelligence." [Wikipedia:Arcopallium] synonym: "arched pallium" RELATED [BTO:0003408] synonym: "archistriatum" RELATED [BM:ARCO, http://www.avianbrain.org/archistriatum.html] xref: BTO:0003408 ! arcopallium xref: BM:ARCO ! archistriatum is_a: UBERON:0000481 ! multitissue structure relationship: part_of UBERON:0007333 ! avian pallium [Term] id: UBERON:0007351 name: nucleus isthmo-opticus synonym: "nucleus isthmoopticus" RELATED [BTO:0003411] xref: BTO:0003411 ! nucleus isthmo-opticus is_a: UBERON:0000481 ! multitissue structure relationship: part_of UBERON:0007333 ! avian pallium [Term] id: UBERON:0000206 name: pharyngeal gill def: "Gills of vertebrates are developed in the walls of the pharynx along a series of gill slits opening to the exterior. In fish, the gills are located on both sides of the pharynx. Gills are made of filaments which help increase surface area for oxygen exchange. In bony fish, the gills are covered by a bony cover called an operculum. When a fish breathes, it opens its mouth at regular times and draws in a mouthful of water. It then draws the sides of its throat together, forcing the water through the gill openings. The water passes over the gills on the outside. Valves inside the mouth keep the water from escaping through the mouth again. The operculum can be very important in adjusting the pressure of water inside of the pharynx to allow proper ventilation of the gills. Lampreys and sharks lack an operculum, they have multiple gill openings. Also, they must use different methods to force water over the gills. In sharks and rays, this ventilation of the gills is achieved either by the use of spiracles or ram ventilation (ventilation by constantly swimming). Although some animals use this method it is much better for animals to use a spiracle because they are less susceptible to injury." [Wikipedia:Gill#Vertebrate_gills] is_a: UBERON:0002535 ! gill relationship: adjacent_to UBERON:0001042 ! chordate pharynx xref: ANISEED:1235300 ! Pharyngeal gill created_by: cjm creation_date: 2009-04-18T01:18:17Z [Term] id: UBERON:0011627 name: orbital part of frontal bone def: "The orbital or horizontal part of the frontal bone (pars orbitalis) consists of two thin triangular plates, the orbital plates, which form the vaults of the orbits, and are separated from one another by a median gap, the ethmoidal notch." [Wikipedia:Orbital_part_of_frontal_bone] synonym: "pars orbitalis ossis frontalis" EXACT LATIN [Wikipedia:Orbital_part_of_frontal_bone] synonym: "pars orbitalis" RELATED [Wikipedia:Orbital_part_of_frontal_bone] synonym: "pars orbitalis (os frontale)" EXACT [FMA:52849] xref: FMA:52849 ! orbital part of frontal bone is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0000209 ! tetrapod frontal bone relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium relationship: in_lateral_side_of UBERON:0002517 {source="FMA-abduced-lr"} ! basicranium [Term] id: UBERON:0000209 name: tetrapod frontal bone def: "In humans: A bone resembling a cockleshell in two portions the squama frontalis, corresponding with the region of the forehead, and an orbital or horizontal portion, the pars orbitalis, which enters into the formation of the roofs of the orbital and nasal cavities." [Wikipedia:Frontal_bone] comment: Taxon notes: fused in humans, paired in other animals Development notes: In the mouse the parietal originates from cephalic paraxial mesoderm (Jiang 2000; Morriss-Kay 2001), whereas in the chicken it is traced back to either mesodermal (Noden 1978) or neural crest (Couly 1992, 1993). synonym: "frontal bone" NARROW SENSU [FMA:52734, MA:0001466] synonym: "frontal" NARROW [AAO:0000206] synonym: "os frontal" NARROW SENSU [Wikipedia:Frontal_bone] xref: FMA:52734 ! Frontal bone xref: GAID:226 ! frontal bone xref: MA:0001466 ! frontal bone xref: VHOG:0001324 ! frontal bone (also: UBERON:0000210 'tetrapod parietal bone') (also: UBERON:0004866 'actinopterygian frontal bone') xref: EMAPA:19016 ! frontal bone xref: AAO:0000206 ! frontal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Gray136.png/200px-Gray136.png xref: MESH:A02.835.232.781.375 ! frontal bone is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0010428 {source="FMA"} ! flat bone relationship: part_of UBERON:0003113 {source="cjm"} ! dermatocranium relationship: part_of UBERON:0001703 ! neurocranium relationship: overlaps UBERON:0001697 ! orbit xref: ncithesaurus:Frontal_Bone ! Frontal Bone xref: SCTID:181793006 ! Entire frontal bone xref: VSAO:0000208 ! frontal bone relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone synonym: "os frontale" RELATED LATIN [Wikipedia:Frontal_bone] xref: http://upload.wikimedia.org/wikipedia/commons/5/5b/Frontal_bone.png xref: UMLS:C0016732 [Term] id: UBERON:0004865 name: actinopterygian parietal bone def: "Dermal bone that covers the otic region and may articulate with its antimere medially, with the frontal bone anteriorly, the pterotic laterally, the supraoccipital medio-posteriorly, and the epiotic and extrascapula latero-posteriorly. The parietal is a paired bone.[TAO]" [TAO:0000486, TAO:GA_TG] synonym: "frontal bone" NARROW [FMA:52734] synonym: "parietal bone" NARROW SENSU [TAO:0000486] synonym: "post parietal" RELATED [ZFA:0000486] synonym: "actinopterygian parietal" EXACT [] xref: TAO:0000486 ! parietal bone xref: ZFA:0000486 ! parietal bone xref: VHOG:0001327 ! interparietal bone (also: UBERON:0002229 'interparietal bone') is_a: UBERON:0002514 ! intramembranous bone relationship: part_of UBERON:0003110 {source="ZFA"} ! otic region relationship: part_of UBERON:0003113 {source="ZFA"} ! dermatocranium relationship: part_of UBERON:0001703 {source="ZFA"} ! neurocranium relationship: part_of UBERON:0004339 {source="PMID:11523816"} ! vault of skull property_value: external_definition "Dermal bone that covers the otic region and may articulate with its antimere medially, with the frontal bone anteriorly, the pterotic laterally, the supraoccipital medio-posteriorly, and the epiotic and extrascapula latero-posteriorly. The parietal is a paired bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000486", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps posttemporal-parietal joint (TAO:0002059)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000486", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps inter-parietal joint (TAO:0005245)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000486", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps frontal-parietal joint (TAO:0005255)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000486", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps supraoccipital-parietal joint (TAO:0005264)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000486", date_retrieved="2012-08-14"} synonym: "parietals" RELATED PLURAL [TAO:0000486] property_value: external_comment "The parietal is a flat, commonly squarish or rectangular bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000486", date_retrieved="2012-09-06", source="Curator"} property_value: homology_notes "The homologization of cranial bones of actinopterygians with those of sarcopterygians based on the bone names established in human anatomy is favored in order to permit the building of phylogenetic relationship schemes beyond the taxonomic boundaries of osteichthyans (including tetrapods). (...) In actinopterygians, the terms parietal and postparietal bones have to replace the commonly used terms 'frontal' and 'parietal' bones for the two paired bones on the skull roof.[well established][VHOG]" xsd:string {external_class="VHOG:0001327", ontology="VHOG", source="ISBN:978-3899370805 Arratia G\, Schultze HP\, Wilson MVH\, Mesozoic Fishes 4 - Homology and Phylogeny (2008) p.23-48", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000210 name: tetrapod parietal bone def: "In humans: bone forming side and roof of cranium. Each bone is irregularly quadrilateral in form, and has two surfaces, four borders, and four angles." [Wikipedia:Parietal_bone, ZFA:0000514] comment: Taxon notes: The frontal bone in teleost fish is the homolog of the parietal bone in tetrapods[various]. In many non-mammalian tetrapods, they are bordered to the rear by a pair of postparietal bones that may be solely in the roof of the skull, or slope downwards to contribute to the back of the skull, depending on the species. In the living tuatara, and many fossil species, a small opening, the parietal foramen, lies between the two parietal bones. This opening is the location of a third eye in the midline of the skull, which is much smaller than the two main eyes[WP] synonym: "os parietale" RELATED [Wikipedia:Parietal_bone] synonym: "frontal bone" NARROW [TAO:0000514] synonym: "parietal" NARROW SENSU [AAO:0000390] synonym: "parietal bone" NARROW SENSU [FMA:9613] synonym: "actinopterygian frontal bone" NARROW [TAO:0000514] xref: FMA:9613 ! Parietal bone xref: GAID:229 ! parietal bone xref: MA:0001469 ! parietal bone xref: VHOG:0001324 ! frontal bone (also: UBERON:0000209 'tetrapod frontal bone') (also: UBERON:0004866 'actinopterygian frontal bone') xref: EMAPA:18715 ! parietal bone xref: AAO:0000390 ! parietal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/21/Gray132.png/200px-Gray132.png xref: MESH:A02.835.232.781.651 ! parietal bone xref: VHOG:0001326 ! parietal bone is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0010428 {source="FMA"} ! flat bone relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0004339 {source="PMID:11523816"} ! vault of skull xref: ncithesaurus:Parietal_Bone ! Parietal Bone xref: SCTID:181794000 ! Entire parietal bone synonym: "os parietale" RELATED LATIN [Wikipedia:Parietal_bone] xref: http://upload.wikimedia.org/wikipedia/commons/2/21/Gray132.png property_value: homology_notes "The homologization of cranial bones of actinopterygians with those of sarcopterygians based on the bone names established in human anatomy is favored in order to permit the building of phylogenetic relationship schemes beyond the taxonomic boundaries of osteichthyans (including tetrapods). (...) In actinopterygians, the terms parietal and postparietal bones have to replace the commonly used terms 'frontal' and 'parietal' bones for the two paired bones on the skull roof.[well established][VHOG]" xsd:string {external_class="VHOG:0001326", ontology="VHOG", source="ISBN:978-3899370805 Arratia G\, Schultze HP\, Wilson MVH\, Mesozoic Fishes 4 - Homology and Phylogeny (2008) p.23-48", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0030558 [Term] id: UBERON:0004866 name: actinopterygian frontal bone def: "Dermal bone that bears part of the supraorbital canal and usually covers a large area of the neurocranium occupying part of the ethmoidal, orbitosphenoid, and otic regions. Commonly, the frontal bone articulates with its antimere medially, with lateral ethmoid, orbitosphenoid and pterosphenoid ventrolaterally, with supraorbital bone(s), autosphenotic and pterotic laterally, and with parietal posteriorly.[TAO]." [TAO:0000514] comment: The frontal bone in teleost fish is the homolog of the parietal bone in tetrapods synonym: "frontal bone" NARROW [TAO:0000514] synonym: "actinopterygian frontal bone" EXACT [TAO:0000514] synonym: "actinopterygian frontal" EXACT [TAO:0000514] xref: TAO:0000514 ! frontal bone xref: ZFA:0000514 ! frontal bone xref: VHOG:0001324 ! frontal bone (also: UBERON:0000209 'tetrapod frontal bone') (also: UBERON:0000210 'tetrapod parietal bone') is_a: UBERON:0008907 {source="ZFA"} ! dermal bone relationship: part_of UBERON:0003113 {source="ZFA"} ! dermatocranium relationship: overlaps UBERON:0001697 {source="ZFA-modified"} ! orbit relationship: part_of UBERON:0001703 {source="ZFA"} ! neurocranium relationship: part_of UBERON:0004339 {source="PMID:11523816"} ! vault of skull property_value: external_definition "Dermal bone that bears part of the supraorbital canal and usually covers a large area of the neurocranium occupying part of the ethmoidal, orbitosphenoid, and otic regions. Commonly, the frontal bone articulates with its antimere medially, with lateral ethmoid, orbitosphenoid and pterosphenoid ventrolaterally, with supraorbital bone(s), autosphenotic and pterotic laterally, and with parietal posteriorly.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000514", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps mesethmoid-frontal joint (TAO:0001678)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000514", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps frontal-pterotic joint (TAO:0001711)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000514", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps inter-frontal joint (TAO:0001922)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000514", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps lateral ethmoid-frontal joint (TAO:0002032)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000514", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps frontal-parietal joint (TAO:0005255)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000514", date_retrieved="2012-08-14"} synonym: "frontals" RELATED PLURAL [TAO:0000514] property_value: external_comment "The frontal bone may be paired or unpaired. The frontal bone of actinopterygians is homologous to the parietal of tetrapods. Actinopterygians do not have a frontal bone. For details, see Schultze (2008) and Wiley (2008).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000514", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0002229 name: interparietal bone def: "the bone of the cranium that lies above and anterior to the occipital bone in some mammals." [MP:0000077, Wikipedia:Interparietal_bone] comment: Taxon notes: rarely present in humans[PMID:3654370]. Editor notes: consider splitting classes for inter-parietal and post-parietal. postparietals paired in reptiles, fused in mammals. synonym: "inter-parietal bone" EXACT [EMAPA:19017] synonym: "interparietal" EXACT [EHDAA:9530] synonym: "post-parietal bone" RELATED [VHOG:0001327] synonym: "postparietal bone" RELATED [VHOG:0001327] synonym: "postparietal" RELATED [VHOG:0001327] synonym: "inca bone" RELATED [Wikipedia:Interparietal_bone] synonym: "os interparietale" RELATED [Wikipedia:Interparietal_bone] synonym: "ossicle of Goethe" RELATED [Wikipedia:Interparietal_bone] xref: FMA:75748 ! Interparietal bone xref: MA:0001467 ! interparietal bone xref: EHDAA:9530 ! interparietal xref: EMAPA:19017 ! inter-parietal bone xref: VHOG:0001327 ! interparietal bone (also: UBERON:0004865 'actinopterygian parietal bone') xref: SCTID:369438005 ! Entire interparietal bone is_a: UBERON:0001474 ! bone element relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0003113 {source="Kardong", notes="vault series"} ! dermatocranium relationship: part_of UBERON:0004339 {source="PMID:11523816"} ! vault of skull relationship: homologous_to UBERON:0004865 ! actinopterygian parietal bone relationship: only_in_taxon NCBITaxon:40674 {source="MP:0000077"} ! Mammalia relationship: develops_from UBERON:0006251 {evidence="definitional"} ! interparietal bone primordium relationship: anterior_to UBERON:0001676 ! occipital bone property_value: homology_notes "The homologization of cranial bones of actinopterygians with those of sarcopterygians based on the bone names established in human anatomy is favored in order to permit the building of phylogenetic relationship schemes beyond the taxonomic boundaries of osteichthyans (including tetrapods). (...) In actinopterygians, the terms parietal and postparietal bones have to replace the commonly used terms 'frontal' and 'parietal' bones for the two paired bones on the skull roof.[well established][VHOG]" xsd:string {external_class="VHOG:0001327", ontology="VHOG", source="ISBN:978-3899370805 Arratia G\, Schultze HP\, Wilson MVH\, Mesozoic Fishes 4 - Homology and Phylogeny (2008) p.23-48", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0010750 name: prefrontal bone def: "a bone separating the lacrimal and frontal bones in many tetrapod skulls" [Wikipedia:Prefrontal_bone] comment: Taxon notes: It first evolved in the sarcopterygian clade Rhipidistia, which includes lungfish and the Tetrapodomorpha. The prefrontal is found in most modern and extinct lungfish, amphibians and reptiles. It is very small, fused to the frontals or lost in many groups of coelurosaurian theropod dinosaurs and is completely absent in their modern descendants, the birds. The prefrontal was also lost in early mammaliaforms and so is not present in modern mammals either[WP] xref: AAO:0000460 ! prefrontal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/44/Dromaeosaurus_skull_en.svg/180px-Dromaeosaurus_skull_en.svg.png synonym: "prefrontal" BROAD [AAO:0000460] is_a: UBERON:0008907 {source="Kardong"} ! dermal bone relationship: part_of UBERON:0003113 {source="Kardong", notes="orbital series"} ! dermatocranium relationship: part_of UBERON:0011156 ! facial skeleton relationship: overlaps UBERON:0001697 {source="Kardong"} ! orbit relationship: adjacent_to UBERON:0000209 ! tetrapod frontal bone relationship: adjacent_to UBERON:0001680 ! lacrimal bone relationship: only_in_taxon NCBITaxon:8287 {source="Wikipedia"} ! Sarcopterygii relationship: dubious_for_taxon NCBITaxon:9606 {source="WP"} ! Homo sapiens [Term] id: UBERON:0011168 name: postfrontal bone def: "a bone behind and above the orbit of which it commonly forms part of the border that is present in many vertebrates and corresponds to the postorbital process of the frontal bone of various birds and mammals " [http://www.merriam-webster.com/dictionary/postfrontal] synonym: "postfrontal" BROAD [] is_a: UBERON:0008907 {source="Kardong"} ! dermal bone relationship: part_of UBERON:0003113 {source="Kardong", notes="orbital series"} ! dermatocranium relationship: part_of UBERON:0011156 ! facial skeleton relationship: overlaps UBERON:0001697 {source="Kardong"} ! orbit relationship: present_in_taxon NCBITaxon:8570 {source="Wikipedia"} ! Serpentes [Term] id: UBERON:0011169 name: postorbital bone def: "The postorbital is one of the bones in vertebrate skulls which forms a portion of the dermal skull roof and, sometimes, a ring about the orbit. Generally, it is located behind the postfrontal and posteriorly to the orbital fenestra. In some vertebrates, the postorbital is fused with the postfrontal to create a postorbitofrontal." [Wikipedia:Postorbital_bone] synonym: "postorbital" BROAD [] is_a: UBERON:0008907 {source="Kardong"} ! dermal bone relationship: part_of UBERON:0003113 {source="Kardong", notes="orbital series"} ! dermatocranium relationship: part_of UBERON:0011156 ! facial skeleton relationship: overlaps UBERON:0001697 {source="Kardong"} ! orbit [Term] id: UBERON:0011639 name: frontoparietal bone def: "An anuran dermal bone that usually is paired and roofs the braincase." [AAO:0000207] synonym: "fronto-parietaux" RELATED [AAO:0000207] synonym: "os fronto-parietale" RELATED [AAO:0000207] synonym: "parietaux" RELATED [AAO:0000207] synonym: "parietofrontal" RELATED [AAO:0000207] synonym: "frontoparietal" EXACT [AAO:0000207] is_a: UBERON:0008907 {source="AAO"} ! dermal bone relationship: part_of UBERON:0003113 {source="Kardong", notes="orbital series"} ! dermatocranium relationship: has_fused_element UBERON:0000209 ! tetrapod frontal bone relationship: has_fused_element UBERON:0000210 ! tetrapod parietal bone xref: AAO:0000207 ! frontoparietal [Term] id: UBERON:0000043 name: tendon def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [VSAO:0000073, Wikipedia:Tendon] comment: AO notes: in FMA, tendon is an organ component that with parts dense-irregular-connective-tissue of tendon and dense-irregular-connective-tissue of tendon sheath; we follow VSAO in making it a subtype of the former. In VSAO tendons connect muscle to bone; in WP the def states integument (e.g. auricular muscles) - but JB confirms this is not actually tendon but aponeurosis subset: uberon_slim synonym: "sinew" RELATED [Wikipedia:Tendon] xref: BTO:0001356 xref: FMA:9721 ! Tendon xref: GAID:276 ! tendon xref: VHOG:0001286 ! tendon xref: MA:0000115 ! tendon xref: OpenCyc:Mx4rvVjefJwpEbGdrcN5Y29ycA xref: XAO:0000173 ! tendon xref: ncithesaurus:Tendon ! Tendon xref: galen:Tendon ! tendon xref: OpenCyc:Mx4rvVjefJwpEbGdrcN5Y29ycA ! tendon xref: EHDAA2:0003091 ! tendon xref: AEO:0000091 ! tendon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3c/Achilles-tendon.jpg/200px-Achilles-tendon.jpg xref: MESH:A02.880 ! tendon xref: EV:0100149 ! tendon xref: VSAO:0000073 ! tendon is_a: UBERON:0007846 {source="VSAO"} ! dense regular connective tissue relationship: connects UBERON:0001630 ! muscle organ relationship: connects UBERON:0001474 ! bone element relationship: part_of UBERON:0002204 {source="OG"} ! musculoskeletal system relationship: has_part CL:0000057 {source="AEO"} ! fibroblast relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell xref: SCTID:256667004 ! Entire tendon xref: ZFA:0005647 ! tendon synonym: "tendo" RELATED LATIN [Wikipedia:Tendon] xref: http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg property_value: external_definition "Dense regular connective tissue that connects muscle to bone.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000073", date_retrieved="2012-08-14", source="PSPUB:0000170"} property_value: homology_notes "Phylogenetically, tendinous tissue first appears in the invertebrate chordate Branchiostoma as myosepta. This two-dimensional array of collagen fibers is highly organized, with fibers running along two primary axes. In hagfish the first linear tendons appear and the myosepta have developed specialized regions with unidirectional fiber orientation - a linear tendon within the flat sheet of myoseptum.[well established][VHOG]" xsd:string {external_class="VHOG:0001286", ontology="VHOG", source="DOI:10.1016/S1095-6433(02)00241-6 Summers AP\, Koob TJ\, The evolution of tendon - morphology and material properties. Comparative Biochemistry and Physiology-Part A: Molecular and Integrative Physiology (2002)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0039508 [Term] id: UBERON:0000304 name: tendon sheath def: "A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath" [Wikipedia:Tendon_sheath] synonym: "synovial tendon sheath" EXACT [FMA:45087] synonym: "vagina tendinis" RELATED LATIN [Wikipedia:Tendon_sheath] comment: TODO: add layer relations. 'tendon sheath' GAT in FMA. xref: FMA:76715 ! Tendon sheath xref: FMA:45087 ! synovial tendon sheath is_a: UBERON:0004923 ! organ component layer relationship: surrounds UBERON:0000043 ! tendon xref: BTO:0000051 ! tendon sheath xref: SCTID:361885006 ! Entire tendon sheath xref: ncithesaurus:Tendon_Sheath ! tendon sheath xref: UMLS:C0224856 [Term] id: UBERON:0011233 name: synovial membrane of synovial tendon sheath def: "Synovial sac which surrounds parts of one or more tendons . Examples: synovial tendon sheath of manual digit 2, radial bursa." [FMA:45087, Wikipedia:Synovial_sheath] comment: Alternate def: A synovial sheath is a layer of a tendon sheath containing tendons in the hand and foot. They lie internal to the fibrous tendon sheaths. An example is the common synovial sheath for the flexor tendons. [Wikipedia:Synovial_sheath] synonym: "synovium" BROAD [BTO:0001823] is_a: UBERON:0007616 {source="FMA"} ! layer of synovial tissue relationship: part_of UBERON:0000304 ! tendon sheath xref: FMA:40878 ! synovial membrane of synovial tendon sheath xref: BTO:0001823 ! synovium (also: UBERON:0002018 'synovial membrane of synovial joint') [Term] id: UBERON:0011234 name: fibrous membrane of synovial tendon sheath xref: FMA:40877 ! fibrous membrane of synovial tendon sheath is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0000304 ! tendon sheath [Term] id: UBERON:0008982 name: fascia def: "A dense regular connective tissue that that connects muscles together[WP, modified]." [Wikipedia:Fascia] synonym: "fascia cluster" EXACT [FMA:30318] is_a: UBERON:0007846 {source="Wikipedia"} ! dense regular connective tissue relationship: part_of UBERON:0002204 ! musculoskeletal system relationship: connects UBERON:0001630 {cardinality="2"} ! muscle organ relationship: connects UBERON:0001630 {notes="fasciae connect muscles to other muscles"} ! muscle organ xref: FMA:30318 ! fascia cluster xref: SCTID:181772008 ! Entire fascia xref: BTO:0002930 ! fascia xref: MESH:A02.340 ! fascia xref: EV:0100150 ! fascia xref: ncithesaurus:Fascia ! Fascia xref: UMLS:C0015641 [Term] id: UBERON:0006614 ! aponeurosis name: aponeurosis def: "A sheet of extracellular matrix." [AEO:0000092, Wikipedia:Aponeurosis] comment: AO notes: in ZFA, aponeuroses are subtypes of tendons, but this is inconsistent with tendons being muscle-bone connections synonym: "aponeuroses" RELATED PLURAL [Wikipedia:Aponeurosis] synonym: "aponeurotic" RELATED [Wikipedia:Aponeurosis] xref: FMA:9722 ! aponeurosis xref: EHDAA2:0003092 ! aponeurosis xref: AEO:0000092 ! aponeurosis is_a: UBERON:0000158 {source="FMA"} ! membranous layer relationship: part_of UBERON:0001630 {source="FMA"} ! muscle organ relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell relationship: has_part CL:0002320 {source="AEO"} ! connective tissue cell xref: ncithesaurus:Aponeurosis ! Aponeurosis xref: SCTID:331712004 ! Entire aponeurosis xref: http://upload.wikimedia.org/wikipedia/commons/e/e6/Aponeurosis.png xref: ZFA:0005652 ! aponeurosis xref: UMLS:C0225205 property_value: external_definition "Aponeuroses are layers of flat broad tendons. They have a shiny, whitish-silvery color, and are histologically similar to tendons, but are very sparingly supplied with blood vessels and nerves. When dissected, aponeuroses are papery, and peel off by sections. The primary regions with thick aponeurosis is in the ventral abdominal region, the dorsal lumbar region, and in the palmar region. Their primary function is to join muscles and the body parts the muscles act upon[Wikipedia:Aponeurosis]." xsd:string {source="Wikipedia:Aponeurosis"} [Term] id: UBERON:0000211 name: ligament def: "Nonparenchymatous organ that primarily consists of dense connective tissue aggregated into fasciculi by connective tissue. Examples: sutural ligament, radiate sternocostal ligament, ligament of liver, ovarian ligament[FMA]." [FMA:21496, Wikipedia:Ligament] comment: Note this groups both skeletal and non-skeletal ligaments. What is called a "ligament" in many AOs is actually a skeletal ligament subset: uberon_slim subset: vertebrate_core synonym: "ligament organ" EXACT [FMA:21496] xref: TAO:0001682 ! ligament xref: ZFA:0001675 ! ligament xref: FMA:21496 ! Ligament organ xref: galen:Ligament xref: VHOG:0001272 ! ligament xref: MA:0000113 ! ligament xref: OpenCyc:Mx4rvVjqpZwpEbGdrcN5Y29ycA xref: ncithesaurus:Ligament ! Ligament xref: EFO:0001966 ! ligament xref: MESH:A02.513 ! ligament xref: OpenCyc:Mx4rvVjqpZwpEbGdrcN5Y29ycA ! ligament is_a: UBERON:0007846 {source="VSAO"} ! dense regular connective tissue relationship: has_part UBERON:0007846 ! dense regular connective tissue xref: SCTID:182358004 ! Entire ligament xref: XAO:0004031 ! ligament xref: http://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg property_value: external_definition "Portion of connective tissue that connects bone or cartilage.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001682", date_retrieved="2012-08-14", source="TAO:wd"} property_value: homology_notes "Compared with their Ediacarian predecessor, Cambrian animals in general were characterized by their much stouter bodies. The stoutness of the body is likely due to the formation of ligaments and tendons, which in turn requires the crosslinking of collagen triple helices.[well established][VHOG]" xsd:string {external_class="VHOG:0001272", ontology="VHOG", source="PMID:8710894 Ohno S\, The notion of the Cambrian pananimalia genome. PNAS (1996)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0023685 [Term] id: UBERON:0008846 name: skeletal ligament def: "Ligament organ that primarily consists of regular dense connective tissue aggregated into fasciculi; connects bone and cartilage organs. Examples: sutural ligament, ligament of pinna, tarsal ligament." [FMA:25624, Wikipedia:Ligament#Articular_ligaments] comment: Editor notes: logical definition deliberately made strict to avoid classifying MA:spiral ligament as both nonskeletal and skeletal. see https://sourceforge.net/tracker/?group_id=76834&atid=1205376 synonym: "articular larua" EXACT [Wikipedia:Ligament] synonym: "articular ligament" EXACT [Wikipedia:Ligament] synonym: "true ligament" EXACT [Wikipedia:Ligament] synonym: "ligament" BROAD [ZFA:0001675, VSAO:0000072] is_a: UBERON:0000211 {source="FMA"} ! ligament intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001434 ! skeletal system intersection_of: connects UBERON:0004765 ! skeletal element relationship: connects UBERON:0004765 {notes="bones or cartilage organs"} ! skeletal element relationship: has_part CL:0000057 {source="AEO"} ! fibroblast relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell xref: FMA:25624 ! skeletal ligament xref: MA:0003005 ! skeletal ligament xref: EV:0100144 ! ligament xref: VSAO:0000072 ! ligament xref: AEO:0000090 ! ligament xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Knee_diagram.svg/200px-Knee_diagram.svg.png xref: EHDAA2:0003232 ! ligament xref: GAID:118 ! ligament xref: AAO:0010444 ! ligament xref: SCTID:410744003 ! Entire skeletal ligament property_value: external_definition "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000072", date_retrieved="2012-08-14", source="PSPUB:0000170"} [Term] id: UBERON:0008845 ! nonskeletal ligament name: nonskeletal ligament def: "Ligament organ that primarily consists of dense connective tissue aggregated into fasciculi which may be admixed with smooth muscle. Examples: ligament of liver, ovarian ligament." [FMA:25625] synonym: "non-skeletal ligament" EXACT [] synonym: "fibrous ligament" RELATED [Wikipedia:Ligament] is_a: UBERON:0000211 {source="FMA"} ! ligament xref: FMA:25625 ! nonskeletal ligament xref: MA:0003004 ! nonskeletal ligament disjoint_from: UBERON:0008846 ! skeletal ligament xref: SCTID:410746001 ! Entire ligament, non-skeletal [Term] id: UBERON:0008879 name: ligament of pinna comment: subclasses (anterior, superior, posterior) can be added on request synonym: "ligament of auricle" EXACT [FMA:61035] synonym: "pinna ligament" EXACT [FMA:61035] is_a: UBERON:0008846 {source="FMA"} ! skeletal ligament relationship: part_of UBERON:0001757 {source="MA"} ! pinna xref: FMA:61035 ! ligament of pinna xref: MA:0001228 ! auricular ligament synonym: "auricular ligament" EXACT [MA:0001228] xref: SCTID:362548009 ! Entire ligament of auricle [Term] id: UBERON:0000212 name: toilet claw def: "specialized claw or nail on the foot of certain primates, used for personal grooming." [Wikipedia:Toilet-claw] is_a: UBERON:0001705 ! nail relationship: has_function_in GO:0007625 ! grooming behavior relationship: has_function_in NBO:0000451 {source="Wikipedia"} ! personal grooming created_by: cjm creation_date: 2009-05-19T08:19:58Z [Term] id: UBERON:0000301 name: amniotic cavity def: "The amniotic cavity is formed by the fusion of the parts of the amniotic fold, which first makes its appearance at the cephalic extremity, and subsequently at the caudal end and sides of the embryo. As the amniotic fold rises and fuses over the dorsal aspect of the embryo, the amniotic cavity is formed. [WP,unvetted]." [Wikipedia:Amniotic_cavity] xref: BTO:0000025 xref: FMA:63941 ! Amniotic cavity xref: VHOG:0000855 ! amniotic cavity xref: ncithesaurus:Amniotic_Cavity ! Amniotic Cavity xref: EHDAA:83 ! amniotic cavity xref: EHDAA2:0000119 ! amniotic cavity xref: EMAPA:16079 ! amniotic cavity is_a: UBERON:0000464 ! anatomical space relationship: has_part UBERON:0000173 ! amniotic fluid relationship: develops_in UBERON:0000087 {source="EHDAA2"} ! inner cell mass relationship: located_in UBERON:0012466 {source="EHDAA2"} ! extraembryonic cavities relationship: has_quality PATO:0000608 ! closed xref: SCTID:280366002 ! Entire amniotic cavity synonym: "cavitas amniotica" RELATED LATIN [Wikipedia:Amniotic_cavity] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray31.png property_value: external_definition "The closed sac between the embryo and the amnion, containing the amniotic fluid. [Free_Online_Medical_Dictionary]" xsd:string {ontology="VHOG", external_class="VHOG:0000855", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/amniotic+cavity", source="http://bgee.unil.ch/"} xref: UMLS:C0230976 [Term] id: UBERON:0011145 ! adductor muscle synonym: "adductor" RELATED [] name: adductor muscle def: "A muscle capable of adduction. Adduction is a movement which brings a part of the anatomy closer to the middle sagittal plane of the body. It is opposed to abduction." [Wikipedia:Adduction, Wikipedia:Adductor_muscle] comment: we place the TAO class here even though it is a cranial muscle; it is defined functionally xref: FMA:74998 ! adductor muscle xref: TAO:0002136 ! adductor muscle xref: ZFA:0005268 ! adductor muscle subset: functional_classification is_a: UBERON:0001630 ! muscle organ property_value: external_definition "A muscle that brings a body part closer to the sagittal plane of the body.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002136", date_retrieved="2012-08-14", source="ZFA:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass cranial muscle (TAO:0001953)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002136", date_retrieved="2012-08-14"} [Term] id: UBERON:0011144 ! adductor muscle of hip name: adductor muscle of hip def: "." [Wikipedia:Adductor_muscles_of_the_hip] synonym: "adductor group (leg)" EXACT [MA:0002267] synonym: "muscle of adductor group" RELATED [] is_a: UBERON:0001630 {source="MA"} ! muscle organ is_a: UBERON:0011145 ! adductor muscle relationship: has_muscle_origin UBERON:0001272 ! innominate bone relationship: part_of UBERON:0010709 ! pelvic complex relationship: innervated_by UBERON:0005465 {source="dbpedia", notes="a small part of adductor magnus is innervated by the tibial nerve"} ! obturator nerve xref: BTO:0000030 ! adductor xref: MA:0002267 ! adductor group (leg) xref: SCTID:181670005 ! Entire adductor muscle xref: SCTID:368101007 ! Entire adductor muscle of lower extremity xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Anterior_Hip_Muscles_2.PNG [Term] id: UBERON:0000952 ! adductor muscle name: obsolete adductor muscle comment: obsoleted as it conflated a generic functional grouping with a specific group of muscles in the leg/hip is_obsolete: true consider: UBERON:0011145 ! adductor muscle consider: UBERON:0011144 ! adductor muscle of hip [Term] id: UBERON:0000303 name: adductor longus def: "An adductor muscle that attaches to the hip and femur. In humans, it is a part of the adductor group of the thigh, that as the name suggests adducts the thigh. The adductor longus muscle forms the medial wall of the femoral triangle[WP, generalized]." [Wikipedia:Adductor_longus_muscle] comment: Definition generalized to accommodate AAO class - "Originates on the iliac portion of the ventral iliac rim and inserts on the lateral surface of the M. adductor magnus." [AAO:0010034] synonym: "adductor longus muscle" EXACT [] synonym: "long adductor muscle" RELATED [BTO:0000029] synonym: "musculus adductor longus" RELATED [BTO:0000029] xref: BTO:0000029 xref: FMA:22441 ! Adductor longus xref: AAO:0010034 ! M. adductor longus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Anterior_Hip_Muscles_2.PNG/200px-Anterior_Hip_Muscles_2.PNG is_a: UBERON:0011144 {source="Wikipedia"} ! adductor muscle of hip relationship: part_of UBERON:0000376 ! hindlimb stylopod relationship: has_muscle_origin UBERON:0001275 {source="dbpedia", notes="pubic body just below the pubic crest"} ! pubis relationship: has_muscle_insertion UBERON:0000981 {source="dbpedia", notes="linea aspera"} ! femur xref: SCTID:181686003 ! Entire adductor longus synonym: "Musculus adductor longus" RELATED LATIN [Wikipedia:Adductor_longus_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Anterior_Hip_Muscles_2.PNG property_value: external_definition "Originates on the iliac portion of the ventral iliac rim and inserts on the lateral surface of the M. adductor magnus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010034", date_retrieved="2012-06-20", source="AAO:EJS"} [Term] id: UBERON:0000368 name: adductor brevis def: "The adductor brevis is a muscle in the thigh situated immediately behind the pectineus and adductor longus. It is somewhat triangular in form, and arises by a narrow origin from the outer surfaces of the superior and inferior rami of the pubis, between the gracilis and obturator externus. Its fibers, passing backward, lateralward, and downward, are inserted, by an aponeurosis, into the line leading from the lesser trochanter to the linea aspera and into the upper part of the linea aspera, immediately behind the pectineus and upper part of the adductor longus.[WP]." [Wikipedia:Adductor_brevis_muscle] synonym: "adductor brevis muscle" EXACT [] synonym: "Musculus adductos brevis" EXACT [FMA:22442] xref: BTO:0001288 xref: FMA:22442 ! Adductor brevis xref: OpenCyc:Mx4rv13lfJwpEbGdrcN5Y29ycA ! adductor brevis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Anterior_Hip_Muscles_2.PNG/200px-Anterior_Hip_Muscles_2.PNG is_a: UBERON:0011144 {source="Wikipedia"} ! adductor muscle of hip relationship: part_of UBERON:0000376 ! hindlimb stylopod xref: SCTID:181687007 ! Entire adductor brevis muscle relationship: innervated_by UBERON:0005465 {source="dbpedia"} ! obturator nerve relationship: has_muscle_origin UBERON:0001275 {source="dbpedia", notes="anterior surface of the inferior ramus and body of the pubis"} ! pubis relationship: has_muscle_insertion UBERON:0002504 {source="dbpedia", notes="the lesser trochanter and linea aspera of the femur"} ! lesser trochanter xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Anterior_Hip_Muscles_2.PNG [Term] id: UBERON:0000370 name: adductor magnus def: "An adductor muscle that attaches to the pelvic bone and the femur. In humans, the adductor magnus is a large triangular muscle, situated on the medial side of the thigh. The portion which arises from the ischiopubic ramus (a small part of the inferior ramus of the pubis, and the inferior ramus of the ischium) is called the 'adductor magnesius portion', and the portion arising from the tuberosity of the ischium is called the 'hamstring portion'. The hamstring portion is not considered part of the hamstring group of muscles, but it is adjacent to it.[WP,generalized]." [Wikipedia:Adductor_magnus_muscle] comment: Definition generalized to accommodate AAO class - "Origin by two heads that are separated by a ventral tendon of the M. semitendinosus. One head originates from the ventral border of the pubic portion of the pelvic rim. The other head originates from the ischiatic border of the pelvic rim. The ventral head fuses with accessory head from the M. semitendinosus and inserts along the ventro-medial border of the femur. The dorsal belly merges with the ventral and accessory heads and inserts along the medial surface of the femur." [AAO:0010040] synonym: "adductor magnus muscle" EXACT [] synonym: "musculus adductor magnus" RELATED LATIN [Wikipedia:Adductor_magnus_muscle] xref: BTO:0001312 xref: FMA:22443 ! Adductor magnus xref: galen:AdductorMagnus xref: OpenCyc:Mx4rvuSd6JwpEbGdrcN5Y29ycA ! adductor magnus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Anterior_Hip_Muscles_2.PNG/200px-Anterior_Hip_Muscles_2.PNG is_a: UBERON:0011144 {source="Wikipedia"} ! adductor muscle of hip relationship: part_of UBERON:0000376 ! hindlimb stylopod xref: SCTID:181688002 ! Entire adductor magnus muscle xref: AAO:0010040 ! M. adductor magnus relationship: has_muscle_origin UBERON:0001275 {source="dbpedia", notes="tuberosity of the ischium"} ! pubis relationship: has_muscle_insertion UBERON:0000981 {source="dbpedia"} ! femur relationship: innervated_by UBERON:0005465 {source="dbpedia", notes="posterior branch of obturator nerve and sciatic nerve"} ! obturator nerve relationship: innervated_by UBERON:0001322 {source="dbpedia", notes="posterior branch of obturator nerve and sciatic nerve"} ! sciatic nerve xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Anterior_Hip_Muscles_2.PNG property_value: external_definition "Origin by two heads that are separated by a ventral tendon of the M. semitendinosus. One head originates from the ventral border of the pubic portion of the pelvic rim. The other head originates from the ischiatic border of the pelvic rim. The ventral head fuses with accessory head from the M. semitendinosus and inserts along the ventro-medial border of the femur. The dorsal belly merges with the ventral and accessory heads and inserts along the medial surface of the femur.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010040", date_retrieved="2012-06-20", source="AAO:EJS"} [Term] id: UBERON:0001382 name: pectineus muscle def: "An adductor muscle that attaches to the pelvic bone and the femur. In humans, The pectineus muscle is a flat, quadrangular muscle, situated at the anterior part of the upper and medial aspect of the thigh. It can be classified in the medial compartment of thigh (when the function is emphasized) or the anterior compartment of thigh (when the nerve is emphasized). [WP,generalized]." [Wikipedia:Pectineus_muscle] comment: Definition generalized to accommodate AAO class - "Originates on the lateral border of the ilium and the anterior margin of the pubis. It inserts on the ventral surface of the femoral shaft." [AAO:0010036] synonym: "pectineus" EXACT [] synonym: "musculus pectineus" RELATED LATIN [Wikipedia:Pectineus_muscle] subset: uberon_slim xref: FMA:22440 ! Pectineus xref: MA:0002353 ! pectineus xref: AAO:0010036 ! M. pectineus synonym: "M. pectineus" EXACT [AAO:0010036] xref: ncithesaurus:Pectineus ! Pectineus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Anterior_Hip_Muscles_2.PNG/200px-Anterior_Hip_Muscles_2.PNG xref: SCTID:245017006 ! Entire pectineus muscle is_a: UBERON:0011144 {source="Wikipedia"} ! adductor muscle of hip relationship: part_of UBERON:0000376 ! hindlimb stylopod relationship: has_muscle_origin UBERON:0001275 {source="dbpedia", notes="pectineal line - superior pubic ramus"} ! pubis relationship: has_muscle_insertion UBERON:0000981 {source="dbpedia"} ! femur relationship: innervated_by UBERON:0001267 {source="dbpedia", notes="Femoral nerve sometimes obturator nerve"} ! femoral nerve relationship: innervated_by UBERON:0005465 {source="dbpedia", notes="Femoral nerve sometimes obturator nerve"} ! obturator nerve xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Anterior_Hip_Muscles_2.PNG property_value: external_definition "Originates on the lateral border of the ilium and the anterior margin of the pubis. It inserts on the ventral surface of the femoral shaft.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010036", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C0224447 [Term] id: UBERON:0000950 name: gracilis def: "The most superficial muscle on the medial side of the thigh. It is thin and flattened, broad above, narrow and tapering below. It arises by a thin aponeurosis from the anterior margins of the lower half of the symphysis pubis and the upper half of the pubic arch." [Wikipedia:Gracilis_muscle] comment: Editor's note: AAO has minor and major gracilis, which merge together, attaching the pelvic rim to the tibiofibula - this could be grouped with the mammalian gracilis at some level; note the current insertion site is 'tibia' which would be modified for amphibian tibiafibula subset: uberon_slim synonym: "gracilis muscle" EXACT [BTO:0000536] synonym: "musculus gracilis" EXACT LATIN [Wikipedia:Gracilis_muscle] xref: FMA:43882 ! Gracilis xref: galen:Gracilis xref: MA:0002311 ! gracilis xref: ncithesaurus:Gracilis ! Gracilis xref: BTO:0000536 ! gracilis muscle xref: OpenCyc:Mx4rv7If8pwpEbGdrcN5Y29ycA ! gracilis muscle is_a: UBERON:0011144 {source="Wikipedia"} ! adductor muscle of hip relationship: part_of UBERON:0000376 ! hindlimb stylopod xref: SCTID:181689005 ! Entire gracilis muscle relationship: has_muscle_origin UBERON:0001272 {source="dbpedia", notes="ischiopubic ramus"} ! innominate bone relationship: has_muscle_insertion UBERON:0000979 {source="dbpedia", notes="pes anserinus"} ! tibia relationship: homologous_to UBERON:0011914 {source="Kardong"} ! pubioischiotibialis muscle xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Anterior_Hip_Muscles_2.PNG xref: UMLS:C0224439 [Term] id: UBERON:0011914 ! pubioischiotibialis muscle name: pubioischiotibialis muscle def: "A muscle of lower tetrapods that covers musch of the lower thing and retracts it. Homologous to mammalian gracilis" [ISBN10:0073040584] is_a: UBERON:0001630 {source="Kardong"} ! muscle organ relationship: part_of UBERON:0000376 {source="Kardong"} ! hindlimb stylopod synonym: "pubioischiotibialis" EXACT [] synonym: "M. pubioischiotibialis" EXACT [] [Term] id: UBERON:0011043 name: obturator muscle def: "One of: obturator externus or obturator internus" [Wikipedia:Obturator_muscles] is_a: UBERON:0002000 {source="FMA"} ! gluteal muscle xref: FMA:19083 ! obturator muscle xref: ncithesaurus:Obturator_Muscle ! obturator muscle xref: SCTID:245024007 ! Entire obturator muscle xref: UMLS:C0224421 [Term] id: UBERON:0001368 name: obturator externus def: "An adductor muscle that attaches to the femur and the pelvis. In humans, the obturator externus muscle is a flat, triangular muscle, which covers the outer surface of the anterior wall of the pelvis. It is sometimes considered part of the medial compartment of thigh, and sometimes considered part of the gluteal region. [WP,generalized]." [Wikipedia:Obturator_externus_muscle] comment: Definition generalized to accommodate AAO class - "Originates on the ventro-lateral pelvic rim and inserts on the ventral aspect of the femur, medial to the insertion of the pectineus." [AAO:0010043] subset: uberon_slim synonym: "external obturator" RELATED [Wikipedia:Obturator_externus_muscle] synonym: "external obturatus" RELATED [Wikipedia:Obturator_externus_muscle] synonym: "externus obturator" RELATED [Wikipedia:Obturator_externus_muscle] synonym: "obturator externus" RELATED [Wikipedia:Obturator_externus_muscle] synonym: "obturatorius externus" RELATED [Wikipedia:Obturator_externus_muscle] synonym: "obturatus externus" RELATED [Wikipedia:Obturator_externus_muscle] synonym: "external obturator" EXACT [] xref: FMA:22299 ! Obturator externus xref: MA:0002347 ! obturator externus xref: AAO:0010043 ! M. obturator externus synonym: "M. obturator externus" EXACT [AAO:0010043] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Posterior_Hip_Muscles_1.PNG/200px-Posterior_Hip_Muscles_1.PNG is_a: UBERON:0011043 {source="FMA"} ! obturator muscle is_a: UBERON:0011144 {source="Wikipedia"} ! adductor muscle of hip relationship: attaches_to UBERON:0002503 {source="FMA"} ! greater trochanter relationship: part_of UBERON:0004470 {source="FMA"} ! musculature of pelvic girdle xref: SCTID:245026009 ! Entire obturator externus xref: ncithesaurus:Obturator_Externus_Muscle ! obturator externus muscle synonym: "musculus obturatorius externus" RELATED LATIN [Wikipedia:Obturator_externus_muscle] relationship: has_muscle_origin UBERON:0006803 {source="dbpedia", notes="obturator foramen and obturatory membrane"} ! obturator foramen relationship: has_muscle_insertion UBERON:0000981 {source="dbpedia", notes="trochanteric fossa of femur"} ! femur xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Posterior_Hip_Muscles_1.PNG property_value: external_definition "Originates on the ventro-lateral pelvic rim and inserts on the ventral aspect of the femur, medial to the insertion of the pectineus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010043", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C1518528 [Term] id: UBERON:0011048 name: obturator internus def: "The obturator internus muscle originates on the medial surface of the obturator membrane, the ischium near the membrane, and the rim of the pubis. It exits the pelvic cavity through the lesser sciatic foramen. The obturator internus is situated partly within the lesser pelvis, and partly at the back of the hip-joint. It functions to help laterally rotate extended thigh and abduct flexed thigh, as well as to steady the femoral head in the acetabulum." [Wikipedia:Obturator_internus_muscle] comment: Definition generalized to accommodate AAO class - "Originates on the entire lateral surface of the pelvic rim. Dorsal fibers insert distally to the dorso-medial surface of the caput femoris and ventral fibers extend around the acetabulum to insert on the tendon of the caput femoris." [AAO:0010052] synonym: "internus obturator" RELATED [Wikipedia:Obturator_internus_muscle] synonym: "obturator internus muscle" RELATED [Wikipedia:Obturator_internus_muscle] synonym: "obturatorius internus" RELATED [Wikipedia:Obturator_internus_muscle] synonym: "internal obturator" EXACT [FMA:22298] synonym: "musculus obturator internus" EXACT [FMA:22298] is_a: UBERON:0011043 {source="FMA"} ! obturator muscle relationship: attaches_to UBERON:0002503 {source="FMA"} ! greater trochanter relationship: part_of UBERON:0004470 {source="FMA"} ! musculature of pelvic girdle xref: FMA:22298 ! obturator internus xref: ncithesaurus:Obturator_Internus_Muscle ! obturator internus muscle xref: SCTID:245025008 ! Entire obturator internus xref: AAO:0010052 ! M. obturator internus synonym: "musculus obturatorius internus" RELATED LATIN [Wikipedia:Obturator_internus_muscle] relationship: has_muscle_insertion UBERON:0002503 {source="dbpedia", notes="medial aspect of the Greater trochanter"} ! greater trochanter xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Posterior_Hip_Muscles_1.PNG property_value: external_definition "Originates on the entire lateral surface of the pelvic rim. Dorsal fibers insert distally to the dorso-medial surface of the caput femoris and ventral fibers extend around the acetabulum to insert on the tendon of the caput femoris.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010052", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C1518529 [Term] id: UBERON:0000307 name: blastula alt_id: UBERON:0007011 def: "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] comment: TODO - check relationship with epiblast. Note in FMA this is not a subclass of embryo, but in uberon embryo is the whole organism from zygote onwards and thus includes the blastula subset: inconsistent_with_fma synonym: "blastosphere" RELATED [Wikipedia:Blastula] synonym: "blastula embryo" EXACT [BILA:0000059] xref: BTO:0000128 xref: OGEM:000006 ! blastula (also: UBERON:0000358 'blastocyst') xref: GAID:1294 ! blastula (also: UBERON:0000108 'blastula stage') xref: OpenCyc:Mx4rEetFnKP2EdqAAAACs4vPlg ! blastula xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c6/Blastulation.png/200px-Blastulation.png xref: MESH:A16.254.270.274 ! blastula xref: BILA:0000059 ! blastula embryo is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0000108 ! blastula stage relationship: develops_from UBERON:0007010 ! cleaving embryo [Term] id: UBERON:0004734 ! gastrula name: gastrula alt_id: UBERON:0007012 def: "Organism at the gastrula stage." [Wikipedia:Gastrula, Wikipedia:Trilaminar_blastocyst] comment: We explicitly merge the NCITA terms here synonym: "gastrula embryo" EXACT [BILA:0000060] synonym: "tri-laminar disc" RELATED [UBERON:cjm] synonym: "tri-laminar disk" RELATED [UBERON:cjm] synonym: "trilaminar disc" RELATED [UBERON:cjm] synonym: "trilaminar disk" RELATED [UBERON:cjm] synonym: "trilaminar germ" RELATED [UBERON:cjm] synonym: "trilaminar blastoderm" RELATED [UBERON:cjm] synonym: "blastocystis trilaminaris" RELATED [UBERON:cjm] synonym: "trilaminar blastocyst" RELATED [UBERON:cjm] xref: MIAA:0000179 ! gastrula xref: BTO:0001403 ! gastrula xref: GAID:1302 ! gastrula xref: MESH:A16.254.412 ! gastrula xref: BILA:0000060 ! gastrula embryo xref: FBbt:00005317 ! gastrula embryo is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0000109 ! gastrula stage relationship: develops_from UBERON:0000307 ! blastula xref: ncithesaurus:Gastrula ! Gastrula xref: ncithesaurus:Trilaminar_Embryonic_Disc ! trilaminar embryonic disc xref: UMLS:C0017199 xref: UMLS:C1284022 [Term] id: UBERON:0000309 name: body wall def: "the external portion of an animal body comprised of ectoderm and mesoderm layers that encloses the body cavity." [MP:0003385] synonym: "trunk wall" EXACT [FMA:10427] synonym: "wall of trunk" EXACT [FMA:10427] synonym: "Koerperwand" RELATED [BTO:0000139] xref: BTO:0000139 xref: FMA:10427 ! Body wall xref: galen:BodyWall is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk xref: SCTID:281483004 ! Entire body wall [Term] id: UBERON:0000310 name: breast def: "The breast is the upper ventral region of an animal's torso, particularly that of mammals, including human beings. The breasts of a female primate’s body contain the mammary glands, which secrete milk used to feed infants. Both men and women develop breasts from the same embryological tissues. However, at puberty female sex hormones, mainly estrogens, promote breast development, which does not happen with men. As a result women's breasts become more prominent than men's. [WP,unvetted]." [Wikipedia:Breast] synonym: "mammary part of chest" EXACT [FMA:9601] synonym: "mammary region" EXACT [FMA:9601] xref: BTO:0000149 xref: FMA:9601 ! Breast xref: galen:Breast xref: ncithesaurus:Breast ! Breast xref: GAID:33 ! breast xref: OpenCyc:Mx4rvVjV7ZwpEbGdrcN5Y29ycA ! breast xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Closeup_of_female_breast.jpg/200px-Closeup_of_female_breast.jpg xref: MESH:A01.236 ! breast xref: EV:0100124 ! breast is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0001443 ! chest xref: SCTID:181131000 ! Entire breast synonym: "mamma" RELATED LATIN [Wikipedia:Breast] xref: http://upload.wikimedia.org/wikipedia/commons/6/6e/Closeup_of_female_breast.jpg xref: UMLS:C0006141 [Term] id: UBERON:0000314 name: cecum mucosa def: "A mucosa that is part of a cecum [Automatically generated definition]." [OBOL:automatic] synonym: "Cecal mucosa" EXACT [FMA:14998] synonym: "caecum mucosa" EXACT [OBOL:automatic] synonym: "caecum mucosa of organ" EXACT [OBOL:automatic] synonym: "caecum mucous membrane" EXACT [OBOL:automatic] synonym: "caecum organ mucosa" EXACT [OBOL:automatic] synonym: "cecum mucosa of organ" EXACT [OBOL:automatic] synonym: "cecum mucous membrane" EXACT [OBOL:automatic] synonym: "cecum organ mucosa" EXACT [OBOL:automatic] synonym: "intestinum crassum caecum mucosa" EXACT [OBOL:automatic] synonym: "intestinum crassum caecum mucosa of organ" EXACT [OBOL:automatic] synonym: "intestinum crassum caecum mucous membrane" EXACT [OBOL:automatic] synonym: "intestinum crassum caecum organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of caecum" EXACT [OBOL:automatic] synonym: "mucosa of cecum" EXACT [OBOL:automatic] synonym: "mucosa of intestinum crassum caecum" EXACT [OBOL:automatic] synonym: "mucosa of organ of caecum" EXACT [OBOL:automatic] synonym: "mucosa of organ of cecum" EXACT [OBOL:automatic] synonym: "mucosa of organ of intestinum crassum caecum" EXACT [OBOL:automatic] synonym: "mucous membrane of caecum" EXACT [OBOL:automatic] synonym: "mucous membrane of cecum" EXACT [OBOL:automatic] synonym: "mucous membrane of intestinum crassum caecum" EXACT [OBOL:automatic] synonym: "organ mucosa of caecum" EXACT [OBOL:automatic] synonym: "organ mucosa of cecum" EXACT [OBOL:automatic] synonym: "organ mucosa of intestinum crassum caecum" EXACT [OBOL:automatic] xref: BTO:0000213 xref: FMA:14998 ! Mucosa of cecum is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001153 ! cecum [Term] id: UBERON:0000315 name: subarachnoid space def: "The space between the arachnoid and pia mater." [GOC:add, Wikipedia:Subarachnoid_space, http://sourceforge.net/tracker/?func=detail&atid=1109502&aid=3535256&group_id=76834] synonym: "cavitas subarachnoidea" RELATED LATIN [BTO:0000230] synonym: "spatium leptomeningeum" RELATED LATIN [BTO:0000230] synonym: "spatium subarachnoideum" RELATED LATIN [BTO:0000230] synonym: "subarachnoid cavity" RELATED [BTO:0000230] xref: BTO:0000230 xref: FMA:83716 ! Subarachnoid space xref: GAID:689 ! subarachnoid space xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f8/Gray769.png/200px-Gray769.png xref: MESH:A08.186.566.166.686 ! subarachnoid space intersection_of: UBERON:0000464 ! anatomical space intersection_of: adjacent_to UBERON:0002361 ! pia mater intersection_of: adjacent_to UBERON:0002362 ! arachnoid mater relationship: contains UBERON:0001359 ! cerebrospinal fluid relationship: contains UBERON:0001981 {source="ISBN10:0471888893"} ! blood vessel xref: SCTID:362311001 ! Entire subarachnoid space synonym: "spatium subarachnoideum" RELATED LATIN [Wikipedia:Subarachnoid_space] synonym: "cavum subarachnoideale" RELATED LATIN [Wikipedia:Subarachnoid_space] xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray769-en.svg [Term] id: UBERON:0008334 name: subarachnoid sulcus xref: FMA:75759 ! subarachnoid sulcus is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0000315 ! subarachnoid space [Term] id: UBERON:0002192 name: ventricular system choroidal fissure def: "The narrow cleft along the medial wall of the lateral ventricle along the margins of which the choroid plexus is attached; it lies between the upper surface of the thalamus and lateral edge of the fornix in the central part of the ventricle and between the terminal stria and fimbria hippocampi in the inferior horn[ZFA]." [ISBN:0815318960, ZFA:0001075] comment: Usage notes: not to be confused with optic fissure. the choroidal fissure is a subarachnoid space (via subarachnoid fissure in FMA). AO notes: Most ontologies appear to have switched to using less confusing primary terms for optic and choroidal fissues. Still need to check FMA - two possible terms? CARO notes: is this a groove or a space or a line? Structure notes: relate to lateral ventricle? subset: vertebrate_core synonym: "chorioidal fissure" RELATED [FMA:74512] synonym: "chorioid fissure" RELATED [FMA:74512] synonym: "choroid fissure" RELATED INCONSISTENT [FMA:74512, TAO:0001075] synonym: "lateral ventricle choroid fissure" EXACT [EHDAA2:0000250] synonym: "choroid invagination" RELATED [EHDAA2:0000250] synonym: "choroidal fissure of lateral ventricle" EXACT [FMA:83715] synonym: "ventricular system choroid fissure" EXACT [VHOG:0001756] xref: FMA:74512 ! Choroidal fissure xref: TAO:0001075 ! choroid fissure xref: ZFA:0001075 ! choroidal fissure xref: EHDAA2:0000250 ! lateral ventricle choroid fissure xref: FMA:83715 ! choroidal fissure of lateral ventricle xref: EHDAA:7567 ! choroid invagination xref: EMAPA:17548 ! choroid invagination xref: EMAPA:17768 ! choroid fissure xref: VHOG:0001756 ! ventricular system choroid fissure xref: ncithesaurus:Choroidal_Fissure ! Choroidal Fissure is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0005358 ! ventricle of nervous system disjoint_from: UBERON:0005412 ! optic fissure synonym: "choroidal fissure" RELATED [FMA:74512] xref: UMLS:C0262212 [Term] id: UBERON:0008335 name: ventrolateral sulcus of medulla oblongata def: "A longitudinal sulcus on the anterior surface of the medulla oblongata, lateral to the pyramid, from which emerge the fibers of the hypoglossal nerve." [Dorlands_Medical_Dictionary:MerckSource] synonym: "anterolateral groove of medulla oblongata" RELATED [BTO:0002777] synonym: "sulcus anterolateralis medullae oblongatae" RELATED [BTO:0002777] synonym: "sulcus ventrolateralis medullae spinalis" RELATED [BTO:0002777] synonym: "ventrolateral sulcus of spinal cord" RELATED [BTO:0002777] synonym: "anterolateral sulcus of medulla" EXACT [FMA:83797] synonym: "sulcus anterolateralis medullae oblongatae" EXACT LATIN [FMA:TA] synonym: "ventrolateral fissure of medulla" EXACT [FMA:83797] synonym: "ventrolateral sulcus" EXACT [FMA:83797] synonym: "ventrolateral sulcus of medulla" EXACT [FMA:83797] is_a: UBERON:0008334 {source="FMA"} ! subarachnoid sulcus relationship: part_of UBERON:0001896 {source="BTO"} ! medulla oblongata xref: BTO:0002777 ! anterolateral sulcus of medulla oblongata xref: FMA:83797 ! ventrolateral sulcus of medulla oblongata xref: SCTID:279291001 ! Entire spinal cord ventrolateral sulcus [Term] id: UBERON:0000319 name: cytotrophoblast def: "The cytotrophoblast (or layer of Langhans) is the inner layer of the trophoblast, interior to the syncytiotrophoblast in an embryo. It serves to anchor the embryonic chorion to the maternal endometrium. Cytotrophoblasts are stem cells in the chorionic villi. During differentiation, mononuclear cytotrophoblast fuse together into the multinucleated syncytiotrophoblasts. The primary villi has only the cytotrophoblast as an axe. [WP,unvetted]." [Wikipedia:Cytotrophoblast] comment: Editors note: todo - unify with EHDAA2, which distinguishes multiple types of cytotrophoblast synonym: "cellular trophoblast" EXACT [FMA:83039] synonym: "cytotrophoblastic cell" RELATED [FMA:83039] synonym: "cytotrophoblastic cell layer" EXACT [UBERON:cjm] synonym: "Langhans' layer" RELATED [BTO:0000322] synonym: "layer of Langhans" RELATED [] xref: BTO:0000322 xref: FMA:83039 ! Cytotrophoblast xref: ncithesaurus:Cytotrophoblast ! Cytotrophoblast xref: EHDAA:127 ! cytotrophoblast xref: EHDAA:152 ! cytotrophoblast xref: EHDAA:89 ! cytotrophoblast xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/df/Gray36.png/200px-Gray36.png xref: EMAPA:16067 ! cytotrophoblast is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000088 ! trophoblast relationship: adjacent_to UBERON:0000453 ! decidua basalis relationship: adjacent_to UBERON:0000371 ! syncytiotrophoblast xref: SCTID:308841008 ! Entire cytotrophoblast synonym: "cytotrophoblastus" RELATED LATIN [Wikipedia:Cytotrophoblast] xref: http://upload.wikimedia.org/wikipedia/commons/d/df/Gray36.png xref: VHOG:0000683 ! cytotrophoblast property_value: external_definition "A derivative layer of the trophoblast, the cells of which retain their boundaries and contribute to the extraembryonic mesoderm [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.189, see_Kardong_KV][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000683", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0230960 [Term] id: UBERON:0000320 name: duodenal mucosa alt_id: UBERON:0003348 def: "A mucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "Doudenal mucosa" EXACT [FMA:14942] synonym: "Duodenal mucous membrane" EXACT [FMA:14942] synonym: "mucous membrane of duodenum" EXACT [OBOL:automatic] synonym: "mucosa of duodenum" EXACT [OBOL:automatic] synonym: "duodenum mucosa" RELATED [BTO:0000367] xref: BTO:0000367 xref: FMA:14942 ! Mucosa of duodenum xref: EMAPA:27235 ! mucosa of duodenum of gut intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002114 ! duodenum xref: SCTID:362146003 ! Entire duodenal mucous membrane [Term] id: UBERON:0000322 name: cerebral lobe comment: set/singular synonym: "Cerebral lobes" EXACT [FMA:77800] synonym: "Cerebral lobes set" EXACT [FMA:77800] xref: BTO:0000445 xref: FMA:77800 ! Set of cerebral lobes is_a: UBERON:0002619 ! region of cerebral cortex synonym: "lobi cerebri" EXACT LATIN [FMA:TA, FMA:77800] xref: SCTID:272632001 ! Entire cerebral lobe synonym: "set of cerebral lobes" RELATED [FMA:77800] [Term] id: UBERON:0000323 name: late embryo comment: TODO - check fetus/embryo. WP: An embryo is a multicellular diploid eukaryote in its earliest stage of development, from the time of first cell division until birth, hatching, or germination. In humans, it is called an embryo until about eight weeks after fertilization (i.e. ten weeks LMP), and from then it is instead called a fetus. synonym: "embryo late growth stage" RELATED [BTO:0000449] synonym: "embryo late stage" RELATED [BTO:0000449] synonym: "fetus" NARROW [BTO:0000449] xref: BTO:0000449 xref: FMA:63919 ! Fetus xref: ncithesaurus:Fetus ! Fetus xref: EFO:0001323 ! fetus xref: GAID:552 ! fetus xref: OpenCyc:Mx4rvZfC2ZwpEbGdrcN5Y29ycA ! fetus xref: MESH:A16.378 ! fetus is_a: UBERON:0000922 ! embryo relationship: existence_ends_with UBERON:0007220 ! late embryonic stage xref: SCTID:83418008 ! fetus xref: FBbt:00005333 ! late embryo xref: UMLS:C0015965 xref: CALOHA:TS-0360 ! Fetus [Term] id: UBERON:0004716 name: conceptus def: "The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]." [Wikipedia:Conceptus, BTO:0003834] synonym: "embryo plus adnexa" EXACT [] xref: Wikipedia:Conceptus ! conceptus xref: BTO:0003834 ! conceptus xref: EHDAA2:0003235 ! conceptus xref: EHDAA2:0000001 ! human conceptus xref: AEO:0000194 ! conceptus is_a: UBERON:0000061 ! anatomical structure relationship: existence_ends_with UBERON:0000068 ! embryo stage relationship: existence_starts_with UBERON:0000068 ! embryo stage relationship: has_part UBERON:0000478 ! extraembryonic structure relationship: has_part UBERON:0002050 ! embryonic structure relationship: develops_from CL:0000365 ! zygote xref: ncithesaurus:Conceptus ! Conceptus xref: UMLS:C1516779 [Term] id: UBERON:0000922 name: embryo def: "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [BTO:0000379, FB:FBrf0039741, FB:FBrf0041814, GO:0009790, Wikipedia:Embryo] comment: Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo subset: uberon_slim subset: vertebrate_core synonym: "developmental tissue" RELATED [] synonym: "developing organism" RELATED [BILA:0000056] synonym: "embryonic organism" EXACT [BILA:0000056] xref: BTO:0000379 xref: EHDAA:38 ! embryo xref: FBbt:00000052 ! embryo xref: FMA:69068 ! Embryo xref: GAID:963 ! embryo xref: MAT:0000226 ! embryo xref: MIAA:0000019 ! developmental tissue (also: UBERON:0005423 'developing anatomical structure') xref: XAO:0000113 ! embryo xref: OGEM:000001 ! embryo xref: ncithesaurus:Embryo ! Embryo xref: EFO:0001367 ! embryo xref: OpenCyc:Mx4rwP1ceZwpEbGdrcN5Y29ycA ! embryo xref: EHDAA2_RETIRED:0003236 ! embryo xref: EHDAA2:0000002 ! human embryo xref: ZFA:0000103 ! embryo xref: AEO:0000169 ! embryo xref: EMAPA:16039 ! embryo xref: MESH:A16.254 ! embryo xref: BILA:0000056 ! embryonic organism xref: VHOG:0001766 ! embryo xref: http://neurolex.org/wiki/Category:Embryonic_organism is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_ends_with UBERON:0000068 ! embryo stage intersection_of: existence_starts_with UBERON:0000068 ! embryo stage xref: AAO:0011035 ! embryo xref: SCTID:57991002 ! Entire embryo xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Wrinkledfrog_embryos.jpg xref: VHOG:0001766 ! embryo property_value: has_relational_adjective "embryonic" xsd:string xref: UMLS:C0013935 [Term] id: UBERON:0005889 name: zygote cortex synonym: "cortex" BROAD [XAO:0000216, AAO:0010327] comment: Usage notes: candidate for obsoletion xref: XAO:0000216 ! cortex xref: AAO:0010327 ! cortex is_a: UBERON:0000470 ! cell part relationship: part_of CL:0000365 ! zygote [Term] id: UBERON:0000326 name: pancreatic juice def: "Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach." [GO:0030157] synonym: "succus pancreaticus" RELATED [BTO:0000504] xref: BTO:0000504 xref: FMA:62973 ! Pancreatic juice xref: GAID:1166 ! pancreatic juice xref: MESH:A12.200.567 ! pancreatic juice is_a: UBERON:0000456 ! bodily secretion relationship: secreted_by UBERON:0001264 ! pancreas [Term] id: UBERON:0000328 name: gut wall synonym: "wall of gut" EXACT [FMA:45653] synonym: "wall of digestive tract" EXACT [] synonym: "wall of alimentary tract" RELATED [] xref: BTO:0000547 xref: FMA:45653 ! Wall of gut is_a: UBERON:0000060 ! anatomical wall relationship: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0000331 name: ileal mucosa def: "A mucosa that is part of a ileum [Automatically generated definition]." [OBOL:automatic] synonym: "ileal mucous membrane" EXACT [FMA:14956] synonym: "ileum mucosa" EXACT [FMA:14956] synonym: "ileum mucosa" EXACT [OBOL:automatic] synonym: "ileum mucosa of organ" EXACT [OBOL:automatic] synonym: "ileum mucous membrane" EXACT [OBOL:automatic] synonym: "ileum organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of ileum" EXACT [OBOL:automatic] synonym: "mucosa of organ of ileum" EXACT [OBOL:automatic] synonym: "mucous membrane of ileum" EXACT [OBOL:automatic] synonym: "organ mucosa of ileum" EXACT [OBOL:automatic] xref: BTO:0000619 xref: FMA:14956 ! Mucosa of ileum is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002116 ! ileum xref: SCTID:85458007 ! Ileal mucous membrane structure [Term] id: UBERON:0000341 name: throat def: "In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted]." [Wikipedia:Throat] comment: Taxon notes: The hyoid bone and the clavicle are the only bones located in the throat of mammals. synonym: "gula" RELATED LATIN [] xref: BTO:0000828 xref: FMA:228738 ! Throat xref: ncithesaurus:Throat ! Throat xref: OpenCyc:Mx4rwQtO_JwpEbGdrcN5Y29ycA ! throat xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Throat_Diagram.png/200px-Throat_Diagram.png is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000974 ! neck xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Throat_Diagram.png property_value: has_relational_adjective "gular" xsd:string xref: UMLS:C0230069 [Term] id: UBERON:0004923 name: organ component layer xref: FMA:82485 ! Organ component layer subset: upper_level is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000060 ! anatomical wall [Term] id: UBERON:0000344 name: mucosa def: "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]" [Wikipedia:Mucous_membrane] comment: AO notes: FMA has mucosa vs region of mucosa; these are subtypes of Mucosa: Mucosa of gallbladder, tongue, .... The following are subtypes of Region of mucosa: Mucosa of zone of stomach, trachea, bronchus, dorsum of tongue.... Depends on whether the covered area is an organ or organ component. Uberon does not regard organ vs organ component as crucial distinction and thus collapses these into a single class deliberately synonym: "mucosa of organ" EXACT [FMA:85355] synonym: "mucous membrane" EXACT [FMA:85355] synonym: "organ mucosa" EXACT [FMA:85355] synonym: "region of mucosa" RELATED [FMA:85358] synonym: "mucosa of organ part" EXACT [FMA:85358] synonym: "mucosal region" EXACT [FMA:85358] synonym: "tunica mucosa" RELATED [BTO:0000886] xref: BTO:0000886 xref: FMA:85355 ! Mucosa xref: ncithesaurus:Mucosa ! Mucosa xref: GAID:297 ! mucous membrane xref: FMA:85358 ! Region of mucosa xref: galen:Mucosa ! mucosa xref: OpenCyc:Mx4rvmKNOpwpEbGdrcN5Y29ycA ! mucous membrane xref: http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png xref: EHDAA2:0003234 ! mucous membrane xref: AEO:0000199 ! mucous membrane xref: MESH:A10.615.550 ! mucous membrane xref: EV:0100382 ! mucosa is_a: UBERON:0004923 ! organ component layer relationship: capable_of GO:0070254 ! mucus secretion relationship: spatially_disjoint_from UBERON:0000009 ! submucosa xref: SCTID:361693009 ! Entire mucous membrane synonym: "tunica mucosa" RELATED LATIN [Wikipedia:Mucous_membrane] xref: http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png property_value: has_relational_adjective "mucosal" xsd:string xref: UMLS:C0026724 [Term] id: UBERON:0000030 name: lamina propria def: "A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions." [Wikipedia:Lamina_propria] comment: Editor notes: need to implement rules such that "lamina propria of X" is classified as part of some "mucosa of X" subset: uberon_slim synonym: "lamina propria mucosa" EXACT [] synonym: "lamina propria mucosae" EXACT [] synonym: "tunica propria" RELATED [BTO:0002330] xref: ncithesaurus:Lamina_Propria ! Lamina Propria xref: BTO:0002330 ! lamina propria xref: FMA:62517 ! Lamina propria xref: SCTID:298225002 ! Lamina propria mucosae xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fb/GI_Organization.svg/250px-GI_Organization.svg.png is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0000344 ! mucosa relationship: composed_primarily_of UBERON:0011825 ! loose connective tissue relationship: immediately_deep_to UBERON:0000483 ! epithelium xref: UMLS:C1179187 [Term] id: UBERON:0006676 ! muscularis mucosa name: muscularis mucosa def: "A the thin layer of smooth muscle found in most parts of the gastrointestinal tract, located outside the lamina propria mucosae and separating it from the submucosa[WP]." [Wikipedia:Muscularis_mucosae] synonym: "muscularis mucosae" EXACT [FMA:68413] synonym: "laminar muscularis mucosa" RELATED [Wikipedia:Muscularis_mucosae] synonym: "lamina muscularis mucosa" RELATED [BTO:0004839] xref: FMA:68413 ! Muscularis mucosae xref: BTO:0004839 ! muscularis mucosa is_a: UBERON:0001135 {source="FMA"} ! smooth muscle tissue relationship: part_of UBERON:0001555 {source="BTO"} ! digestive tract relationship: part_of UBERON:0000344 {source="Wikipedia"} ! mucosa relationship: immediately_deep_to UBERON:0000030 ! lamina propria xref: ncithesaurus:Muscularis_Mucosa ! Muscularis Mucosa xref: galen:MuscularisMucosae xref: SCTID:370140002 ! Muscularis mucosae xref: http://upload.wikimedia.org/wikipedia/commons/5/54/Gray1058.png xref: UMLS:C0225357 [Term] id: UBERON:0000009 name: submucosa def: "A layer of dense irregular connective tissue in the gastrointestinal tract that supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle (fibers running circularly within layer of longitudinal muscle). [WP,unvetted]." [Wikipedia:Submucosa] subset: uberon_slim synonym: "organ submucosa" EXACT [FMA:85391] synonym: "submucosa of organ" EXACT [FMA:85391] synonym: "region of submucosa" EXACT [FMA:85392] synonym: "submucosa of region of organ" EXACT [FMA:85392] synonym: "submucous layer" RELATED [BTO:0002107] synonym: "tela submucosa" RELATED [BTO:0002107] synonym: "tunica submucosa" RELATED [] xref: FMA:85391 ! Submucosa xref: FMA:85392 ! Region of submucosa xref: ncithesaurus:Submucosa ! Submucosa xref: BTO:0002107 ! submucosa xref: SCTID:68439008 ! Tunica submucosa xref: http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png is_a: UBERON:0004923 ! organ component layer relationship: composed_primarily_of UBERON:0011822 ! dense irregular connective tissue xref: http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png property_value: has_relational_adjective "submucosal" xsd:string xref: UMLS:C0225344 [Term] id: UBERON:0006660 ! muscle layer name: muscle layer def: "A region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis." [Wikipedia:Muscular_layer] comment: AO notes: NCITA class appears to be defined more generally synonym: "muscularis" RELATED [] synonym: "muscularis layer" EXACT [FMA:45634] synonym: "muscular layer" EXACT [OBOL:automatic] synonym: "muscular coat" RELATED [Wikipedia:Muscularis_externa] synonym: "muscularis propria" RELATED [Wikipedia:Muscularis_externa] synonym: "transverse muscular fibers" RELATED [Wikipedia:Muscularis_externa] synonym: "tunica muscularis" RELATED [Wikipedia:Muscularis_externa] synonym: "muscularis externa" RELATED [BTO:0004838] synonym: "tunica externa" RELATED [BTO:0004838] synonym: "tunica muscularis" EXACT LATIN [BTO:0004838] is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: composed_primarily_of UBERON:0002385 ! muscle tissue relationship: spatially_disjoint_from UBERON:0000009 ! submucosa relationship: spatially_disjoint_from UBERON:0006676 ! muscularis mucosa xref: FMA:45634 ! Muscle layer xref: BTO:0004838 ! muscular coat xref: SCTID:86915006 ! Muscularis propria xref: ncithesaurus:Muscle_Layer ! Muscle Layer property_value: external_definition "An outer layer of smooth muscle surrounding a hollow or tubular organ as the bladder, esophagus, large intestine, small intestine, stomach, ureter, uterus, and vagina that often consists of an inner layer of circular fibers serving to narrow the lumen of the organ and an outer layer of longitudinal fibers serving to shorten its length[BTO]." xsd:string {source="BTO:0004838"} xref: UMLS:C0225358 [Term] id: UBERON:0012368 ! circular muscle layer name: circular muscle layer synonym: "inner muscularis" RELATED [FMA:62899] synonym: "inner muscularis layer" RELATED [FMA:62899] synonym: "circular smooth muscle" RELATED [BTO:0005213] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0006660 ! muscle layer xref: FMA:62899 ! inner muscle layer xref: BTO:0005213 ! circular smooth muscle [Term] id: UBERON:0012369 ! longitudinal muscle layer name: longitudinal muscle layer synonym: "outer muscularis" RELATED [FMA:62900] synonym: "outer muscularis layer" RELATED [FMA:62900] synonym: "longitudinal smooth muscle" RELATED [BTO:0005214] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0006660 ! muscle layer xref: FMA:62900 ! outer muscle layer xref: BTO:0005214 ! longitudinal smooth muscle [Term] id: UBERON:0000345 name: myelin def: "a dielectric (electrically insulating) material that forms a layer, the myelin sheath, usually around only the axon of a neuron. Myelin is about 40 % water; the dry mass of myelin is about 70 - 85 % lipids and about 15 - 30 % proteins. Some of the proteins that make up myelin are myelin basic protein (MBP), myelin oligodendrocyte glycoprotein (MOG), and proteolipid protein (PLP). The primary lipid of myelin is a glycolipid called galactocerebroside (GalC). The intertwining hydrocarbon chains of sphingomyelin serve to strengthen the myelin sheath." [Wikipedia:Myelin] comment: editor note: cede to other ontology. Retired in ncit xref: BTO:0000894 xref: FMA:62977 ! Myelin xref: ncithesaurus:Myelin ! Myelin is_a: UBERON:0000061 ! anatomical structure [Term] id: UBERON:0000346 name: myelin membrane comment: BTO has def The multilamellar myelin membrane is a specisalised lipid-rich domain of the glial cell plasma membrane. FMA has primary term name Myelinated plasma membrane of Schwann cell synonym: "myelinated plasma membrane of Schwann cell" EXACT [FMA:73417] xref: BTO:0000895 xref: FMA:73417 ! Myelinated plasma membrane of Schwann cell is_a: UBERON:0000470 ! cell part relationship: has_part UBERON:0000345 ! myelin [Term] id: UBERON:0000347 name: myelin sheath def: "the insulating envelope that surrounds nerve fibers or axons." [MP:0003871] synonym: "medullary sheath" RELATED [BTO:0000900] xref: BTO:0000900 xref: FMA:62983 ! Myelin sheath xref: ncithesaurus:Myelin_Sheath ! Myelin Sheath xref: GO:0043209 ! myelin sheath xref: GAID:731 ! myelin sheath xref: MESH:A08.637.600.500 ! myelin sheath is_a: UBERON:0000470 ! cell part relationship: has_part UBERON:0000345 ! myelin xref: UMLS:C0026973 [Term] id: UBERON:0011096 name: lacrimal nerve def: "The lacrimal nerve is the smallest of the three branches of the ophthalmic division of the trigeminal nerve." [Wikipedia:Lacrimal_nerve] is_a: UBERON:0002003 {source="ncithesaurus"} ! peripheral nerve relationship: branch_of UBERON:0000348 {source="FMA"} ! ophthalmic nerve xref: FMA:52628 ! lacrimal nerve xref: SCTID:280218007 ! Entire lacrimal nerve xref: http://upload.wikimedia.org/wikipedia/commons/4/45/Gray787.png [Term] id: UBERON:0000349 name: limbic system def: "A set of midline structures surrounding the brainstem of the mammalian brain, originally described anatomically, e.g., hippocampal formation, amygdala, hypothalamus, cingulate cortex. Although the original designation was anatomical, the limbic system has come to be associated with the system in the brain subserving emotional functions. As such, it is very poorly defined and doesn't correspond closely to the anatomical meaning any longer. [BirnLex]. including the hippocampus, amygdala, anterior thalamic nuclei, and limbic cortex, which support a variety of functions including emotion, behavior, long term memory, and olfaction [Wikipedia]." [BIRNLEX:Limbic_system, Wikipedia:Limbic_system] comment: obsoletion recommended. The current part_of children were chosen as the intersection of what is stated in wikipedia and in the FMA. NIF: We are including Limbic System because it is still used by neuroscientists and others, but as a data annotation term, it is very poor because it is not a clearly defined entity. xref: BTO:0000928 xref: FMA:242000 ! Limbic system xref: GAID:615 ! limbic system xref: OpenCyc:Mx4rwAeba5wpEbGdrcN5Y29ycA ! limbic system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Brain_limbicsystem.jpg/200px-Brain_limbicsystem.jpg xref: MESH:A08.186.211.577 ! limbic system is_a: UBERON:0000467 {source="GO"} ! anatomical system relationship: part_of UBERON:0001890 ! forebrain xref: SCTID:361342009 ! Entire limbic system xref: ncithesaurus:Limbic_System ! limbic system xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Brain_limbicsystem.jpg xref: UMLS:C0023715 [Term] id: UBERON:0000351 name: nuchal ligament def: "a fibrous membrane, which, in the neck, represents the supraspinal ligaments of the upper vertebræ. As it is required for running, not all animals have a nuchal ligament" [Wikipedia:Nuchal_ligament] synonym: "paddywhack" RELATED [Wikipedia:Paddywhack] synonym: "paxwax" RELATED [] synonym: "ligament of neck" EXACT [FMA:13427] synonym: "ligamentum nuchae" EXACT LATIN [FMA:13427] xref: BTO:0000952 xref: FMA:13427 ! Ligamentum nuchae xref: EMAPA:19207 ! ligamentum nuchae is_a: UBERON:0008846 ! skeletal ligament relationship: part_of UBERON:0012477 {source="BTO"} ! dorsal part of neck relationship: attaches_to UBERON:0001676 ! occipital bone relationship: attaches_to UBERON:0002413 ! cervical vertebra xref: SCTID:166962007 ! Entire ligament of neck [Term] id: UBERON:0000353 name: parenchyma def: "functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin[WP]." [Wikipedia:Parenchyma] xref: FMA:45732 ! Parenchyma xref: ncithesaurus:Parenchyma ! Parenchyma xref: EHDAA:3015 ! parenchyma xref: EHDAA:3905 ! parenchyma xref: EHDAA:3999 ! parenchyma xref: EHDAA:4005 ! parenchyma xref: EHDAA:6899 ! parenchyma xref: EHDAA:6903 ! parenchyma xref: EHDAA:6994 ! parenchyma xref: EHDAA:8086 ! parenchyma xref: EHDAA:9182 ! parenchyma xref: EHDAA:9190 ! parenchyma xref: EHDAA:9196 ! parenchyma xref: EHDAA:9202 ! parenchyma is_a: UBERON:0000064 ! organ part xref: UMLS:C0933845 [Term] id: UBERON:0003937 ! sex gland name: sex gland def: "any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction" [MP:0000653] synonym: "reproductive gland" EXACT [MA:0001751] synonym: "genitalia gland" EXACT [OBOL:automatic] synonym: "gland of genitalia" EXACT [OBOL:automatic] synonym: "gland of reproductive system" EXACT [OBOL:automatic] synonym: "reproductive system gland" EXACT [OBOL:automatic] xref: MA:0001751 ! reproductive gland is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000990 ! reproductive system subset: organ_slim [Term] id: UBERON:0010147 ! male accessory sex gland name: male accessory sex gland def: "Any gland, other than the gonad, associated with the genital tract, such as the ampulla of the ductus deferens and the bulbourethral, prostate and vesicular glands of the male." [BTO:0004798] is_a: UBERON:0005399 {source="BTO"} ! male reproductive gland relationship: part_of UBERON:0000079 ! male reproductive system xref: BTO:0004798 ! accessory sex gland [Term] id: UBERON:0005300 name: obsolete reproductive gland is_obsolete: true replaced_by: UBERON:0003937 ! sex gland [Term] id: UBERON:0005398 name: female reproductive gland xref: BTO:0000254 ! female reproductive gland xref: MA:0000383 ! female reproductive gland intersection_of: UBERON:0003937 ! sex gland intersection_of: part_of UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0003134 ! female reproductive organ subset: organ_slim def: "A sex gland that is part of a female reproductive system." [OBOL:automatic] [Term] id: UBERON:0005399 name: male reproductive gland xref: MA:0000399 ! male reproductive gland xref: BTO:0000080 ! male reproductive gland intersection_of: UBERON:0003937 ! sex gland intersection_of: part_of UBERON:0000079 ! male reproductive system subset: organ_slim def: "A sex gland that is part of a male reproductive system." [OBOL:automatic] [Term] id: UBERON:0000359 ! preputial gland name: preputial gland def: "An exocrine gland that are located in front of the genitals of some mammals (including mice) and produce pheromones[WP]." [Wikipedia:Preputial_gland] synonym: "preputial glands" EXACT [FMA:71652] synonym: "preputial glands set" EXACT [FMA:71652] synonym: "glandulae preputiales" EXACT LATIN [FMA:TA, FMA:71652] synonym: "set of preputial glands" RELATED PLURAL [FMA:71652] xref: FMA:71652 ! Set of preputial glands xref: ncithesaurus:Prepucial_Gland_MMHCC ! Preputial Gland xref: SCTID:278916008 ! Entire preputial gland is_a: UBERON:0001821 ! sebaceous gland relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: dubious_for_taxon NCBITaxon:9606 {source="ISBN10:0123813611"} ! Homo sapiens relationship: part_of UBERON:0000990 ! reproductive system property_value: homology_notes "There is debate about whether humans have functional homologues to preputial glands." xsd:string {source="http://en.wikipedia.org/wiki/Preputial_gland#Human_homologoues"} property_value: external_definition "the paired, lobulated, modified sebaceous glands of the corona, the neck of the glans penis, and the inner surface of the prepuce with pheromonal functions in male rodents; male preputial secretions strongly attract females, may accelerate estrus, and have been implicated in intermale aggression; homologous to the clitoral glands (aka female preputial glands) in female rodents; there is no true anatomical equivalent in humans." xsd:string {ontology="MP", external_class="MP:0002717"} subset: organ_slim xref: UMLS:C1947929 [Term] id: UBERON:0005301 name: male preputial gland def: "One of the sebaceous glands of the corona and neck of the glans penis." [MP:0002717] comment: FMA:19653 was previously placed here, but ISBN10:0123813611 states that no true equivalent in humans. See also https://sourceforge.net/tracker/index.php?func=detail&aid=3588536&group_id=76834&atid=1109502 synonym: "preputial gland" BROAD [BTO:0001111, EMAPA:30640] synonym: "preputial gland of male" EXACT [] synonym: "preputial gland of penis" EXACT [FMA:19653] synonym: "gland of Tyson" RELATED [BTO:0001111] xref: EMAPA:30640 ! preputial gland xref: BTO:0001111 ! preputial gland xref: MA:0000403 ! male preputial gland xref: EMAPA:30502 ! preputial gland of male of preputial swelling of male xref: EMAPA:30659 ! preputial gland of male of prepuce of male of penis is_a: UBERON:0010147 ! male accessory sex gland intersection_of: UBERON:0000359 ! preputial gland intersection_of: part_of UBERON:0003101 ! male organism relationship: part_of UBERON:0001332 ! prepuce of penis relationship: never_in_taxon NCBITaxon:9606 {source="ISBN10:0123813611"} ! Homo sapiens xref: ncithesaurus:Preputial_Gland ! Preputial Gland relationship: part_of UBERON:0000079 {is_inferred="true", source="reference_0000032"} ! male reproductive system xref: UMLS:C0227956 [Term] id: UBERON:0005302 name: female preputial gland def: "The paired, lobulated, modified sebaceous glands located on the side of the clitoris in female rodents; in contrast to the preputial glands in male rodents, clitoral glands are a minor source of olfactory stimuli contributing to sexual attractivity; unlike other sebaceous glands, they undergo progressive atrophy of the glandular portion with marked ductal ectasia as rodents age; there is no true anatomical equivalent in humans[MP]." [MP:0011834, https://sourceforge.net/tracker/index.php?func=detail&aid=3588536&group_id=76834&atid=1109502] synonym: "clitoral gland" EXACT [MA:0001702] synonym: "preputial gland of female" EXACT [EMAPA:30499] xref: MA:0001703 ! female preputial gland xref: MA:0001702 ! clitoral gland xref: EMAPA:30499 ! preputial gland of female of preputial swelling of female xref: EMAPA:30711 ! preputial gland of female of prepuce of female xref: BTO:0003119 ! clitoral gland intersection_of: UBERON:0000359 ! preputial gland intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0000474 ! female reproductive system relationship: never_in_taxon NCBITaxon:9606 {source="ISBN10:0123813611"} ! Homo sapiens xref: ncithesaurus:Clitoral_Gland ! Clitoral Gland property_value: external_definition "large, lobulated, modified sebaceous glands located on the side of the clitoris in female mice; little is known about their function and, unlike other sebaceous glands, they undergo progressive atrophy of the glandular portion with marked ductal ectasia as mice age; there is no equivalent gland in humans." xsd:string {source="MP", source="MGI:J:63036"} xref: UMLS:C2699356 [Term] id: UBERON:0012327 name: pearly penile papule def: "small saliences on the ridge of the glans of the male genital organs." [Wikipedia:Hirsuties_coronae_glandis] synonym: "preputial gland of penis" RELATED INCONSISTENT [FMA:19653] synonym: "hirsuties coronae glandis" EXACT PLURAL [Wikipedia:Hirsuties_coronae_glandis] synonym: "hirsutoid papilloma" EXACT [Wikipedia:Hirsuties_coronae_glandis] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0001332 {source="FMA"} ! prepuce of penis relationship: present_in_taxon NCBITaxon:9606 {source="Wikipedia:Preputial_gland"} ! Homo sapiens disjoint_from: UBERON:0005301 ! male preputial gland xref: FMA:19653 ! preputial gland of penis [Term] id: UBERON:0012328 name: penile spine def: "Keratinized structures along the glans and/or shaft of their penis that may be involved in sexual selection." [Wikipedia:Penile_spines] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0000989 ! penis relationship: present_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: UBERON:0008331 name: clitoral smooth muscle synonym: "clitoris smooth muscle" RELATED [BTO:0005000] is_a: UBERON:0001135 {source="BTO"} ! smooth muscle tissue relationship: part_of UBERON:0002411 {source="BTO"} ! clitoris intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002411 ! clitoris xref: BTO:0005000 ! clitoral smooth muscle def: "A smooth muscle tissue that is part of a clitoris." [OBOL:automatic] [Term] id: UBERON:0000360 name: obsolete rectal gland is_obsolete: true consider: UBERON:0004757 consider: UBERON:0004758 consider: UBERON:0004759 consider: UBERON:0004760 [Term] id: UBERON:0004757 name: rectal gland def: "An evagination of the terminal portion of the intestine of Elasmobranchii. Function formerly thought to be related to digestion or excretion, but now considered to secrete high concentrations of excess sodium chloride. Found also in the coelacanth Latimeria chalumnae[BTO]." [BTO:0001157] comment: does not include FMA:15724 Rectal gland // epithelial tissue gland - concentrates & secretes excess Na & Cl in sharks. large shark liver produces copious amounts of urea, making the shark hyperosmotic to seawater, & thus a shark acts like a fresh water fish, constantly gaining water. Excess salts are concentrated by the rectal gland and secreted xref: BTO:0001157 is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0001052 ! rectum relationship: capable_of GO:0055078 ! sodium ion homeostasis relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata xref: SCTID:80455007 ! Rectal gland subset: organ_slim [Term] id: UBERON:0004758 name: salt gland def: "an organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles. In sharks, salt glands are found in the rectum, but in birds and reptiles, they are found in or on the skull, in the area of the eyes, nostrils or mouth. In crocodiles, the salt is excreted through the tongue. Such glands work by active transport via sodium-potassium pump that moves salt from the blood into the gland, where it can be excreted as a concentrated solution. Salt glands function to keep salt balance, and allow marine vertebrates to drink seawater[WP]." [Wikipedia:Salt_gland] subset: functional_classification xref: GAID:1235 ! salt gland xref: BTO:0001204 ! salt gland xref: MESH:A13.811 ! salt gland intersection_of: UBERON:0002530 ! gland intersection_of: capable_of GO:0055078 ! sodium ion homeostasis relationship: confers_advantage_in ENVO:00000569 ! marine habitat subset: organ_slim [Term] id: UBERON:0004759 name: salt gland of cranial region def: "A salt gland located in the cranium or cranial region." [OBOL:automatic] intersection_of: UBERON:0002530 ! gland intersection_of: capable_of GO:0055078 ! sodium ion homeostasis intersection_of: part_of UBERON:0003128 ! cranium subset: organ_slim [Term] id: UBERON:0004760 name: gland of anal canal def: "A gland that is part of an anal canal [Automatically generated definition]." [OBOL:automatic, Wikipedia:Anal_gland] synonym: "rectal gland" RELATED [] synonym: "anal gland" RELATED [] synonym: "anal sac" RELATED SENSU [Wikipedia:Anal_gland] synonym: "gland of anus" RELATED [] synonym: "gland of anal canal" EXACT [OBOL:automatic] xref: FMA:15724 ! Rectal glan xref: FMA:15720 ! anal gland xref: EMAPA:27233 ! gland of mucosa of rostral part of anal canal xref: EMAPA:27221 ! gland of mucosa of caudal part of anal canal xref: EMAPA:27543 ! gland of mucosa of anal canal intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000159 ! anal canal xref: ncithesaurus:Anal_Gland ! Anal Gland (also: UBERON:0011253 'gland of anal sac') subset: organ_slim xref: SCTID:245448005 ! Entire anal gland xref: UMLS:C0162322 [Term] id: UBERON:0011252 ! scent gland name: scent gland def: "Scent glands are exocrine glands found in most mammals. They produce semi-viscous secretions which contain pheromones and other semiochemical compounds. These odor-messengers indicate information such as status, territory marking, mood, and sexual power. The odor may be subliminal—not consciously detectable. Though it is not their primary function, the salivary glands may also function as scent glands in some animals." [Wikipedia:Scent_gland] xref: http://upload.wikimedia.org/wikipedia/commons/8/85/Civetglands.png is_a: UBERON:0002530 ! gland relationship: has_function_in GO:0035636 ! multi-organism signaling xref: BTO:0002068 ! scent gland xref: MESH:A13.820 ! scent gland property_value: external_definition "Exocrine glands in animals which secrete scents which either repel or attract other animals, e.g. perianal glands of skunks, anal glands of weasels, musk glands of foxes, ventral glands of wood rats, and dorsal glands of peccaries[MESH:A13.820]." xsd:string {source="MESH:A13.820"} [Term] id: UBERON:0013234 name: violet gland def: "The violet gland or supracaudal gland is an important gland located on the upper surface of the tail of certain mammals, including European badgers and canids such as foxes, wolves the domestic dog, as well as the domestic cat. It is used for intra species signalling, scent marking, and contributes to the strong odor of foxes in particular." [Wikipedia:Violet_gland] synonym: "supracaudal gland" RELATED [] is_a: UBERON:0011252 ! scent gland relationship: part_of UBERON:0007812 ! post-anal tail relationship: only_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: UBERON:0008978 ! anal sac name: anal sac def: "In carnivores, either of two sacs found between the internal and external anal sphincters, lined with sebaceous glands and in some species with apocrine glands." [BTO:0001681] is_a: UBERON:0000064 {source="BTO"} ! organ part relationship: part_of UBERON:0001245 {source="BTO"} ! anus xref: SCTID:362169000 ! Entire anal sac xref: BTO:0001681 ! anal sac xref: MESH:A13.073 ! anal sac [Term] id: UBERON:0011253 name: gland of anal sac def: "." [Wikipedia:Anal_gland] synonym: "anal sac gland" EXACT [] synonym: "anal gland" RELATED [] synonym: "musk gland" RELATED [] is_a: UBERON:0011252 ! scent gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: part_of UBERON:0008978 ! anal sac xref: ncithesaurus:Anal_Gland ! anal gland (also: UBERON:0004760 'gland of anal canal') xref: SCTID:91610001 ! Anal sac glands xref: UMLS:C0162322 [Term] id: UBERON:0013212 name: anal sac gland secretion synonym: "anal gland secretion" RELATED [] synonym: "hyena butter" RELATED SENSU [Wikipedia:Hyena_butter] synonym: "musk" RELATED [] intersection_of: UBERON:0000456 ! bodily secretion intersection_of: secreted_by UBERON:0011253 ! gland of anal sac [Term] id: UBERON:0012281 ! perianal gland name: perianal gland synonym: "circumanal gland" RELATED [MESH:A13.734] synonym: "perianal gland" RELATED [MESH:A13.734] is_a: UBERON:0002365 ! exocrine gland relationship: part_of UBERON:0001353 ! anal region xref: MESH:A13.734 ! perianal gland xref: ncithesaurus:Perianal_Gland ! perianal gland [Term] id: UBERON:0011263 ! femoral gland name: femoral gland def: "A gland arranged along a row on the underside of the hindlimb in some lizards[Kardong]" [ISBN10:0073040584] is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0002199 {source="Kardong"} ! integument relationship: part_of UBERON:0000376 {source="Kardong"} ! hindlimb stylopod relationship: part_of UBERON:0002330 {source="Kardong"} ! exocrine system [Term] id: UBERON:0011264 name: femoral pore def: "Femoral pores are a part of a holocrine secretory gland found on the inside of the thighs of certain lizards and amphisbaenians which releases pheromones to attract mates or mark territory. In certain species only the male has these pores and in other species, both sexes have them, with the males being larger.[1] Femoral pores appear as a series of pits or holes within a row of scales on the ventral portion of the animal's thigh." [Wikipedia:Femoral_pore] comment: Taxon notes: Femoral pores are present in all genera in the families Cordylidae, Crotaphytidae, Hoplocercidae, Iguanidae, Phrynosomatidae, and Xantusiidae.[1] They are absent in all genera in the Anguidae, Chamaeleonidae, Dibamidae, Helodermatidae, Scincidae, Xenosauridae, and Varanidae families.[1] They are present in other lizards and amphisbaenians quite variably, some geckoes, Phelsuma, for example have these pores, others in the same family do not[WP] intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0011263 ! femoral gland [Term] id: UBERON:0000362 name: renal medulla def: "The renal medulla is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the arcuate arterioles. The arcuate arterioles each in turn branch into interlobular arterioles, which finally reach the glomeruli. At the glomerulus the blood reaches a highly disfavourable pressure gradient and a large exchange surface area, which forces the serum portion of the blood out of the vessel into the renal tubules. Flow continues through the renal tubules, including the proximal tubule, the Loop of Henle, and finally leaves the kidney by means of the collecting duct, leading to the renal ureter. The renal medulla (latin renes medulla = kidney middle) contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood. The renal medulla is hypertonic to the filtrate in the nephron and aids in the reabsorption of water. [WP,unvetted]." [Wikipedia:Renal_medulla] synonym: "renal medullae" EXACT [FMA:86327] synonym: "renal medullae set" EXACT [FMA:86327] synonym: "kidney medulla" EXACT [OBOL:automatic] synonym: "medulla of kidney" EXACT [OBOL:automatic] synonym: "medullary pyramids" EXACT [FMA:74268] synonym: "renal pyramids" EXACT [FMA:74268] synonym: "renal pyramids set" EXACT [FMA:74268] synonym: "renal marrow" RELATED [BTO:0001167] synonym: "medulla renalis" EXACT LATIN [FMA:TA, FMA:74268] synonym: "pyramides renales" EXACT LATIN [FMA:TA, FMA:74268] xref: BTO:0001167 xref: FMA:74268 ! set of renal pyramids xref: ncithesaurus:Renal_Medulla ! Renal Medulla xref: GAID:425 ! kidney medulla xref: galen:MedullaOfKidney ! medulla of kidney xref: MA:0000373 ! kidney medulla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/69/Illu_kidney.jpg/200px-Illu_kidney.jpg xref: EMAPA:19279 ! renal medulla xref: MESH:A05.810.453.466 ! kidney medulla (also: UBERON:0001228 'renal papilla') is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000958 ! medulla intersection_of: part_of UBERON:0002113 ! kidney relationship: has_function_in GO:0070295 ! renal water reabsorption xref: SCTID:30737000 ! Structure of medulla of kidney xref: http://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg synonym: "set of renal pyramids" RELATED [FMA:74268] synonym: "set of medullary pyramids" RELATED [FMA:74268] xref: UMLS:C0022664 [Term] id: UBERON:0004200 ! kidney pyramid name: kidney pyramid alt_id: UBERON:0005098 alt_id: UBERON:0002449 def: "Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts[GO]. One of a number of pyramidal masses seen on longitudinal section of the kidney; collectively, they constitute the renal medulla, and contain part of the secreting tubules and the collecting tubules[BTO]. Renal pyramids (or malpighian pyramids) are cone-shaped tissues of the kidney. The renal medulla is made up of 8 to 18 of these conical subdivisions. The broad base of each pyramid faces the renal cortex, and its apex, or papilla, points internally. The pyramids appear striped because they are formed by straight parallel segments of nephrons. [WP,unvetted]." [GO:0072056, Wikipedia:Renal_pyramids, BTO:0003926] comment: not the same as FMA:50609 Pyramid (which is a volume / dimensional entity) synonym: "pyramid" BROAD [GO:0072056] synonym: "renal pyramid" EXACT [Wikipedia:Renal_pyramids] synonym: "malpighian pyramid" EXACT [Wikipedia:Renal_pyramids] synonym: "medullary pyramid" RELATED [] synonym: "pyramis renalis" RELATED [BTO:0003926] synonym: "malphigian pyramid" RELATED [BTO:0003926] synonym: "pyramid of Malphigi" RELATED [ncithesaurus:Pyramid_of_Malpighi] xref: BTO:0003926 ! renal pyramid xref: FMA:258870 ! Renal pyramid xref: MA:0001654 ! renal pyramid xref: ncithesaurus:Renal_Pyramid ! Renal Pyramid xref: BTO:0003926 ! renal pyramid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Kidney_PioM.png/200px-Kidney_PioM.png is_a: UBERON:0000061 ! anatomical structure is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000362 ! renal medulla xref: SCTID:361328001 ! Entire renal pyramid xref: ncithesaurus:Pyramid_of_Malpighi ! Pyramid of Malpighi synonym: "pyramides renales" RELATED LATIN [Wikipedia:Renal_pyramids] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png xref: UMLS:C1514613 xref: UMLS:C0227629 [Term] id: UBERON:0000363 name: reticuloendothelial system def: "A part of the immune system that consists of the phagocytic cells located in reticular connective tissue. The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen. The Kupffer cells of the liver and tissue histiocytes are also part of the RES. A lymphoma of the reticuloendothelial system is called reticuloendotheliosis[WP]." [Wikipedia:Reticuloendothelial_system] synonym: "mononuclear phagocyte system" EXACT [FMA:84189] synonym: "lymphoreticular system" EXACT [Wikipedia:Reticuloendothelial_system] synonym: "lymphoreticular" RELATED [BioMart:BioMart] synonym: "RES" EXACT [Wikipedia:Reticuloendothelial_system] xref: BTO:0001174 xref: FMA:84189 ! Mononuclear phagocyte system xref: ncithesaurus:Reticuloendothelial_System ! Reticuloendothelial System xref: GAID:1004 ! reticuloendothelial system xref: MESH:A15.382.812 ! reticuloendothelial system xref: EV:0100048 ! lymphoreticular system is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002405 ! immune system xref: SCTID:278874002 ! Entire lymphoreticular system xref: UMLS:C0035287 [Term] id: UBERON:0000364 name: obsolete rootlet synonym: "Rootlets" EXACT [FMA:76787] synonym: "Rootlets set" EXACT [FMA:76787] xref: BTO:0001192 consider: FMA:76787 ! Set of rootlets is_obsolete: true synonym: "fila radicularia" EXACT LATIN [FMA:TA, FMA:76787] [Term] id: UBERON:0002435 name: striatum def: "A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO]." [Wikipedia:Striatum, GOC:jl] comment: AO notes: FMA divides striatum of neuraxis into 4, neostriatum is seperate class. In NIF these are synonyms. TODO - check striatum vs corpus striatum see http://en.wikipedia.org/wiki/Striatum#History. Check caudoputamen subset: uberon_slim synonym: "corpus striatum" RELATED [MA:0000891] synonym: "neostriatum" EXACT [GO:0021756, Wikipedia:Striatum] synonym: "striate nucleus" EXACT [GO:0021756, Wikipedia:Striatum] xref: FMA:77618 ! Striatum xref: FMA:83683 ! striatum of neuraxis xref: MA:0000891 ! striatum xref: EFO:0000109 ! obsolete_CNS brain striatum MMHCC xref: NIF_GrossAnatomy:birnlex_1672 ! Striatum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/BrainCaudatePutamen.svg/200px-BrainCaudatePutamen.svg.png xref: BTO:0000418 ! neostriatum xref: MESH:A08.186.211.730.885.105.487.550 ! neostriatum xref: ABA:STR ! Striatum xref: BM:N ! neostriatum is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002420 {source="NIF"} ! basal ganglion relationship: part_of UBERON:0000204 {source="GO"} ! ventral telencephalon relationship: part_of UBERON:0000369 {source="BTO"} ! corpus striatum relationship: spatially_disjoint_from UBERON:0006514 {source="ABA"} ! pallidum xref: ncithesaurus:Striatum ! Striatum xref: http://upload.wikimedia.org/wikipedia/commons/3/33/BrainCaudatePutamen.svg synonym: "striatum of neuraxis" EXACT [FMA:83683] synonym: "neuraxis striatum" EXACT [FMA:83683] property_value: has_relational_adjective "striatal" xsd:string [Term] id: UBERON:0010082 name: future corpus striatum intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: develops_into UBERON:0000369 ! corpus striatum xref: EHDAA2:0000596 ! future corpus striatum def: "A multi-tissue structure that develops_into a corpus striatum." [OBOL:automatic] [Term] id: UBERON:0000369 name: corpus striatum def: "The corpus striatum (striated body) is a compound structure consisting of the caudate nucleus and the lentiform nucleus, which consists of the putamen and the globus pallidus[WP]." [Wikipedia:Corpus_striatum] comment: The term has been used in a few different ways: * It is a pair of nuclear masses which form the basal ganglia, along with the subthalamic nucleus and the substantia nigra. * It may also refer to both the basal ganglia and internal capsule collectively.[2] * According to the 1917 version of Gray's Anatomy, it is the combination of the lentiform nucleus (also known as the lenticular nucleus) and the caudate nucleus * According to BrainInfo it is a part of the basal ganglia comprising the globus pallidus and striatum synonym: "striate body" RELATED [BTO:0001311] synonym: "striated body" RELATED [BTO:0001311] xref: BTO:0001311 xref: EFO:0000381 ! corpus striatum xref: FMA:77616 ! Corpus striatum xref: VHOG:0001175 ! corpus striatum xref: ncithesaurus:Corpus_Striatum ! Corpus Striatum xref: GAID:667 ! corpus striatum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/Gray656.png/200px-Gray656.png xref: EMAPA:17549 ! corpus striatum xref: MESH:A08.186.211.730.885.105.487 ! corpus striatum xref: EV:0100184 ! corpus striatum is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002420 {source="MA"} ! basal ganglion xref: SCTID:279318005 ! Entire corpus striatum relationship: immediate_transformation_of UBERON:0010082 {evidence="definitional"} ! future corpus striatum property_value: homology_notes "Thus, certain telencephalic characters - such as the presence of a pallium divided into lateral, dorsal, and medial formations and a subpallium divided into striatum and septum - appear to characterize all vertebrates. They are primitive characters and are homologous among all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0001175", ontology="VHOG", source="DOI:10.1146/annurev.ne.04.030181.001505\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.487 Figure 14-10", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0010097 xref: CALOHA:TS-0183 ! Corpus striatum [Term] id: UBERON:0002777 name: obsolete neostriatum subset: uberon_slim consider: FMA:77617 ! Neostriatum consider: NIF_GrossAnatomy:birnlex_1672 ! Striatum xref: GAID:669 ! neostriatum is_obsolete: true [Term] id: UBERON:0005382 name: dorsal striatum def: "Those portions of the caudate nucleus and especially the putamen located generally superior to a plane representing the anterior commissure; also called the dorsal basal ganglia; may function in motor activities with cognitive origins." [BTO:0004701, Wikipedia:Dorsal_striatum] synonym: "caudoputamen" RELATED [NIF_GrossAnatomy:nlx_anat_100312] synonym: "striatum dorsale" RELATED [BTO:0004701] synonym: "dorsal basal ganglion" RELATED [BTO:0004701] synonym: "dorsal basal ganglia" RELATED [BTO:0004701] synonym: "corpus striatum" RELATED [Wikipedia:Dorsal_striatum] synonym: "striated body" RELATED [Wikipedia:Dorsal_striatum] xref: MA:0002971 ! dorsal striatum xref: BTO:0004701 ! dorsal striatum xref: FMA:77620 ! dorsal striatum xref: NIF_GrossAnatomy:nlx_anat_1010001 ! Dorsal Striatum xref: ABA:STRd ! Striatum dorsal region is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002435 ! striatum property_value: external_definition "According to the 1917 version of Gray's Anatomy, it is the combination of the lentiform nucleus and the caudate nucleus" xsd:string {source="http://en.wikipedia.org/wiki/Dorsal_striatum"} property_value: external_definition "According to BrainInfo it is a part of the basal ganglia comprising the globus pallidus and striatum" xsd:string {source="http://en.wikipedia.org/wiki/Dorsal_striatum"} property_value: external_definition "It may also refer to both the basal ganglia and the internal capsule collectively." xsd:string {source="http://en.wikipedia.org/wiki/Dorsal_striatum"} property_value: external_definition "It may also refer to the putamen and caudate collectively." xsd:string {source="http://en.wikipedia.org/wiki/Dorsal_striatum"} [Term] id: UBERON:0005383 name: caudate-putamen def: "Regional part of telencephalon in some species, e.g., rodent, equivalent to the dorsal striatum (caudate nucleus and putamen). Unlike the dorsal striatum of primates, for example, the caudoputamen is not split into separate nuclei by the fibers of the internal capsule. Rather, the internal capsule splits into fiber bundles which course through the structure." [NIF_GrossAnatomy:nlx_anat_100312] comment: CHECK - rodents. The caudate nucleus and putamen are separated by a clear white matter bundle in most species but not in rodents (MM) synonym: "caudate putamen" EXACT [] synonym: "caudoputamen" EXACT [NIF_GrossAnatomy:nlx_anat_100312] synonym: "caudateputamen" EXACT [NIF_GrossAnatomy:nlx_anat_100312] xref: MA:0000893 ! caudate-putamen xref: NIF_GrossAnatomy:nlx_anat_100312 ! caudoputamen xref: BTO:0000212 ! caudate putamen xref: EMAPA:19095 ! caudate-putamen xref: ABA:CP ! Caudoputamen xref: BM:Tel-C-Pu ! caudate-putamen xref: EFO:0001912 ! caudate putamen is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0005382 ! dorsal striatum [Term] id: UBERON:0010122 name: future caudate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: develops_into UBERON:0001873 ! caudate nucleus relationship: develops_from UBERON:0010082 {source="EHDAA2"} ! future corpus striatum xref: EHDAA2:0004461 ! future caudate nucleus def: "A nucleus of brain that develops_into a caudate nucleus." [OBOL:automatic] [Term] id: UBERON:0001873 name: caudate nucleus def: "Nucleus of brain which is an elongated crescent-shaped mass lying parallel and adjacent to the lateral ventricle throughout its extent." [Wikipedia:Caudate_nucleus] comment: CHECK - rodents. The caudate nucleus and putamen are separated by a clear white matter bundle in most species but not in rodents (MM) subset: uberon_slim synonym: "caudatus" EXACT [] synonym: "nucleus caudatus" RELATED [BTO:0000211] xref: BTO:0000211 xref: EFO:0000907 ! caudate nucleus xref: FMA:61833 ! Caudate nucleus xref: GAID:670 ! caudate nucleu xref: MA:0000894 ! caudate nucleus xref: MAT:0000513 ! caudate nucleus xref: NIF_GrossAnatomy:birnlex_1373 ! Caudate nucleus xref: ncithesaurus:Caudate_Nucleus ! Caudate Nucleus xref: OpenCyc:Mx4rvvyAjJwpEbGdrcN5Y29ycA ! caudate nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/91/Telencephalon-Horiconatal.jpg/200px-Telencephalon-Horiconatal.jpg xref: EMAPA:18207 ! caudate nucleus xref: MESH:A08.186.211.730.885.105.487.550.184 ! caudate nucleu xref: EV:0100185 ! caudate nucleus xref: BM:Tel-CA ! caudate nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0002435 ! striatum relationship: part_of UBERON:0005383 ! caudate-putamen xref: SCTID:279297002 ! Entire caudate nucleus relationship: immediate_transformation_of UBERON:0010122 {evidence="definitional"} ! future caudate nucleus synonym: "nucleus caudatus" RELATED LATIN [Wikipedia:Caudate_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Telencephalon-Horiconatal.jpg xref: UMLS:C0007461 [Term] id: UBERON:0001874 name: putamen def: "Nucleus of brain which lies ventral to the caudate nucleus and internal capsule and medial to the external capsule. The putamen and caudate nucleus together form the dorsal striatum. It is also one of the structures that comprises the basal ganglia. Through various pathways, the putamen is connected to the substantia nigra and globus pallidus. The main function of the putamen is to regulate movements and influence various types of learning. It employs dopamine to perform its functions. The putamen also plays a role in degenerative neurological disorders, such as Parkinson's disease." [Wikipedia:Putamen] comment: CHECK - rodents. The caudate nucleus and putamen are separated by a clear white matter bundle in most species but not in rodents (MM) subset: uberon_slim synonym: "nucleus putamen" EXACT [] xref: FMA:61834 ! Putamen xref: GAID:671 ! putamen xref: VHOG:0001456 ! putamen xref: MA:0000895 ! putamen xref: NIF_GrossAnatomy:birnlex_809 ! Putamen xref: ncithesaurus:Putamen ! Putamen xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/BrainCaudatePutamen.svg/200px-BrainCaudatePutamen.svg.png xref: MESH:A08.186.211.730.885.105.487.550.784 ! putamen xref: EV:0100187 ! putamen xref: BM:Tel-Pu ! putamen is_a: UBERON:0002308 {source="FMA"} ! nucleus of brain relationship: part_of UBERON:0001869 {source="FMA"} ! cerebral hemisphere relationship: part_of UBERON:0002435 ! striatum relationship: part_of UBERON:0005383 ! caudate-putamen xref: SCTID:281512002 ! Entire putamen xref: http://upload.wikimedia.org/wikipedia/commons/3/33/BrainCaudatePutamen.svg property_value: homology_notes "All nuclei of the mammalian basal ganglia are also present in the oldest vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0001456", ontology="VHOG", source="DOI:10.1016/j.cub.2011.05.001 Stephenson-Jones M\, Samuelsson E\, Ericsson J\, Robertson B\, Grillner S\, Evolutionary conservation of the basal ganglia as a common vertebrate mechanism for action selection. Current Biology (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0034169 [Term] id: UBERON:0008884 name: left putamen intersection_of: UBERON:0001874 ! putamen intersection_of: part_of UBERON:0002812 ! left cerebral hemisphere xref: FMA:72829 ! left putamen def: "A putamen that is part of a left cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0008885 name: right putamen xref: FMA:72828 ! right putamen intersection_of: UBERON:0001874 ! putamen intersection_of: part_of UBERON:0002813 ! right cerebral hemisphere def: "A putamen that is part of a right cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0000371 name: syncytiotrophoblast def: "extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." [Wikipedia:Syncytiotrophoblast, http://embryology.med.unsw.edu.au/Notes/placenta5.htm] synonym: "syncytial trophoblast" EXACT [FMA:83040] synonym: "syntrophoblast" RELATED [] synonym: "syncitiotrophoblast" RELATED [] synonym: "syntrophoblast layer" EXACT [ISBN10:0073040584 "Vertebrates\, Kardong"] xref: BTO:0001335 xref: FMA:83040 ! Syncytial trophoblast xref: ncithesaurus:Syncytiotrophoblast ! Syncytiotrophoblast xref: EHDAA:129 ! syncytiotrophoblast xref: EHDAA:91 ! syncytiotrophoblast xref: EMAPA:16068 ! syncytiotrophoblast is_a: UBERON:0002050 {source="FMA"} ! embryonic structure relationship: part_of UBERON:0004364 {source="EMAPA"} ! ectoplacental cone relationship: part_of UBERON:0000088 {source="BTO"} ! trophoblast relationship: composed_primarily_of CL:0000525 ! syncytiotrophoblast cell xref: SCTID:256965005 ! Entire syncytial trophoblast synonym: "syncitiotrophoblastus" RELATED LATIN [Wikipedia:Syncytiotrophoblast] xref: http://upload.wikimedia.org/wikipedia/commons/d/df/Gray36.png xref: UMLS:C1135936 [Term] id: UBERON:0000311 ! extensor muscle name: extensor muscle def: "A muscle that, upon contraction, tends to straighten a joint or limb. The antagonist of a flexor muscle[BTO]. Any of the muscles that increase the angle between members of a limb, as by straightening the elbow or knee or bending the wrist or spine backward. The movement is usually directed backward, with the notable exception of the knee joint. In humans, certain muscles of the hand and foot are named for this function. In the hand these include the extensor carpi radialis brevis, extensor carpi radialis longus, and extensor carpi ulnaris, which run from the humerus (bone of the upper arm) along the back of the forearm to the metacarpal bones at the back of the hand[Britannica]" [http://www.britannica.com/EBchecked/topic/198909/extensor-muscle] synonym: "extensor" RELATED [] xref: BTO:0000151 xref: FMA:75000 ! extensor muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0004708 ! limb/fin relationship: develops_from UBERON:0010962 ! extensor pre-muscle mass [Term] id: UBERON:0010962 ! extensor pre-muscle mass name: extensor pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group xref: EHDAA2:0000459 ! extensor pre-muscle mass [Term] id: UBERON:0000366 ! flexor muscle name: flexor muscle def: "A muscle that when contracted acts to bend a joint or limb in the body." [BTO:0001257] subset: vertebrate_core synonym: "flexor" RELATED [] xref: BTO:0001257 xref: FMA:74559 ! Flexor xref: FMA:74999 ! flexor muscle xref: ZFA:0005271 ! flexor muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0004708 ! limb/fin relationship: develops_from UBERON:0010977 ! flexor pre-muscle mass xref: TAO:0005271 ! flexor muscle property_value: external_definition "A muscle that decreases the angle of a joint.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005271", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0010977 ! flexor pre-muscle mass name: flexor pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group xref: EHDAA2:0000543 ! flexor pre-muscle mass [Term] id: UBERON:0001521 name: flexor carpi radialis muscle def: "A muscle of the forearm that acts to flex and abduct the manus. [WP,unvetted]." [Wikipedia:Flexor_carpi_radialis_muscle] comment: AO notes - we group the AAO class here, despite the different insertion site - requires vetting "Muscle which originates on the inner border of the humerus and inserts on the carpus." [AAO:0010733] subset: uberon_slim synonym: "flexor carpi radialis" EXACT [MA:0002297] xref: FMA:38459 ! Flexor carpi radialis xref: MA:0002297 ! flexor carpi radialis xref: ncithesaurus:Flexor_Carpi_Radialis ! Flexor Carpi Radialis xref: AAO:0010733 ! M. flexor carpi radialis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/59/Flexor-carpi-radialis.png/200px-Flexor-carpi-radialis.png is_a: UBERON:0000366 ! flexor muscle relationship: has_muscle_origin UBERON:0006806 ! medial epicondyle of humerus relationship: has_muscle_insertion UBERON:0002374 {notes="2 and 3 in human"} ! metacarpal bone relationship: part_of UBERON:0002386 ! forelimb zeugopod xref: http://upload.wikimedia.org/wikipedia/commons/5/59/Flexor-carpi-radialis.png property_value: external_definition "Muscle which originates on the inner border of the humerus and inserts on the carpus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010733", date_retrieved="2012-06-20", source="AAO:MEJ"} xref: SCTID:361816002 ! Entire flexor carpi radialis muscle xref: UMLS:C0224252 [Term] id: UBERON:0001522 name: flexor carpi ulnaris muscle def: "The flexor carpi ulnaris muscle (FCU) is a muscle of the human forearm that acts to flex and adduct the manus. [WP,unvetted]." [Wikipedia:Flexor_carpi_ulnaris_muscle] comment: AO notes: AAO has a class with the same name, the exact insertion point is unclear; consider grouping "Muscle which originates from the medial condyle of the humerus and inserts on the carpus." [AAO:0010734] synonym: "flexor carpi ulnaris" EXACT [Wikipedia:Flexor_carpi_ulnaris_muscle] subset: uberon_slim xref: FMA:38465 ! Flexor carpi ulnaris xref: MA:0002298 ! flexor carpi ulnaris xref: ncithesaurus:Flexor_Carpi_Ulnaris ! Flexor Carpi Ulnaris xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c1/FCU.png/200px-FCU.png is_a: UBERON:0000366 ! flexor muscle relationship: part_of UBERON:0002386 ! forelimb zeugopod xref: SCTID:244985003 ! Entire flexor carpi ulnaris synonym: "musculus flexor carpi ulnaris" RELATED LATIN [Wikipedia:Flexor_carpi_ulnaris_muscle] relationship: has_muscle_insertion UBERON:0001429 {source="dbpedia"} ! pisiform relationship: has_muscle_origin UBERON:0006806 {source="dbpedia", notes="medial epicondyle"} ! medial epicondyle of humerus xref: http://upload.wikimedia.org/wikipedia/commons/c/c1/FCU.png xref: UMLS:C0224254 [Term] id: UBERON:0001523 name: flexor digitorum profundus def: "In human anatomy, the flexor digitorum profundus is a muscle in the forearm that flexes the fingers. It is considered to be an extrinsic muscle because its action is at a different location than the main body of the muscle. Flexor digitorum profundus, along with flexor digitorum superficialis have long tendons that run down the arm and through the carpal tunnel and attach to the palmar side of the phalanges of the fingers. This muscle originates from the upper 3/4ths anterior and medial side of the ulna. Flexor digitorum profundus lies deep to superficialis, but it attaches more distally. To get around this problem profundus's tendons go through the tendons of superficialis, and end up attaching to the distal phalanx. [WP,unvetted]." [Wikipedia:Flexor_digitorum_profundus_muscle] comment: Note that in EMAPA, this is part of the leg, which is presumably a mistake synonym: "flexor digitorum profundus muscle" EXACT [Wikipedia:Flexor_digitorum_profundus_muscle] subset: uberon_slim xref: BTO:0001246 xref: FMA:38478 ! Flexor digitorum profundus xref: MA:0002300 ! flexor digitorum profundus xref: ncithesaurus:Flexor_Digitorum_Profundus ! Flexor Digitorum Profundus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/24/Flexor-digitorum-profundis.png/200px-Flexor-digitorum-profundis.png xref: EMAPA:19319 ! flexor digitorum profundus is_a: UBERON:0000366 {source="BTO"} ! flexor muscle relationship: part_of UBERON:0003822 {source="FMA"} ! upper arm relationship: has_muscle_antagonist UBERON:0007612 {source="dbpedia"} ! extensor digitorum communis synonym: "musculus flexor digitorum profundus" RELATED LATIN [Wikipedia:Flexor_digitorum_profundus_muscle] relationship: has_muscle_insertion UBERON:0004300 {source="dbpedia", notes="base of the distal phalanges of the fingers"} ! distal phalanx relationship: has_muscle_origin UBERON:0001010 {source="dbpedia", notes="upper 3/4 of the volar and medial surfaces of the body of the ulna interosseous membrane and deep fascia of the forearm"} ! diaphysis of ulna xref: http://upload.wikimedia.org/wikipedia/commons/2/24/Flexor-digitorum-profundis.png xref: UMLS:C0224261 [Term] id: UBERON:0001392 name: flexor hallucis longus def: "The Flexor hallucis longus muscle (FHL) is a muscle of the leg. It is one of the deep muscles of the posterior compartment of the leg. The other deep muscles of the leg are flexor digitorum longus and tibialis posterior. FHL is the largest and most powerful of these deep muscles. The Flexor hallucis longus is situated on the fibular side of the leg. It arises from the inferior two-thirds of the posterior surface of the body of the fibula, with the exception of 2.5 cm. at its lowest part; from the lower part of the interosseous membrane; from an intermuscular septum between it and the Peronæi, laterally, and from the fascia covering the Tibialis posterior, medially. The fibers pass obliquely downward and backward, and end in a tendon which occupies nearly the whole length of the posterior surface of the muscle. This tendon lies in a groove which crosses the posterior surface of the lower end of the tibia, the posterior surface of the talus, and the under surface of the sustentaculum tali of the calcaneus; in the sole of the foot it runs forward between the two heads of the Flexor hallucis brevis, and is inserted into the base of the last phalanx of the great toe. The grooves on the talus and calcaneus, which contain the tendon of the muscle, are converted by tendinous fibers into distinct canals, lined by a mucous sheath. As the tendon passes forward in the sole of the foot, it is situated above, and crosses from the lateral to the medial side of the tendon of the Flexor digitorum longus, to which it is connected by a fibrous slip. [WP,unvetted]." [Wikipedia:Flexor_hallucis_longus_muscle] synonym: "flexor hallucis longus muscle" EXACT [Wikipedia:Flexor_hallucis_longus_muscle] subset: uberon_slim xref: FMA:22593 ! Flexor hallucis longus xref: MA:0002301 ! flexor hallucis longus xref: ncithesaurus:Flexor_Hallucis_Longus ! Flexor Hallucis Longus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/92/Gray442.png/200px-Gray442.png is_a: UBERON:0000366 ! flexor muscle relationship: part_of UBERON:0000978 ! leg relationship: has_muscle_insertion UBERON:0004315 {source="dbpedia", notes="Plantar surface; base of distal phalanx of hallux"} ! distal phalanx of pedal digit 1 relationship: innervated_by UBERON:0001323 {source="dbpedia", notes="tibial nerve S1 and S2 nerve roots"} ! tibial nerve relationship: has_muscle_origin UBERON:0001446 {source="dbpedia", notes="fibula posterior aspect of middle 1/3"} ! fibula relationship: homologous_to UBERON:0011909 {source="ISBN10:0073040584"} ! gastrocnemius internus xref: http://upload.wikimedia.org/wikipedia/commons/9/92/Gray442.png xref: SCTID:361826009 ! Entire flexor hallucis longus muscle xref: UMLS:C0224473 [Term] id: UBERON:0011022 name: flexor hallucis brevis def: "The Flexor hallucis brevis arises, by a pointed tendinous process, from the medial part of the under surface of the cuboid bone, from the contiguous portion of the third cuneiform, and from the prolongation of the tendon of the Tibialis posterior which is attached to that bone. It divides in front into two portions, which are inserted into the medial and lateral sides of the base of the first phalanx of the great toe, a sesamoid bone being present in each tendon at its insertion. The medial portion is blended with the Abductor hallucis previous to its insertion; the lateral portion with the Adductor hallucis; the tendon of the Flexor hallucis longus lies in a groove between them; the lateral portion is sometimes described as the first Interosseous plantaris." [Wikipedia:Flexor_hallucis_brevis_muscle] synonym: "flexor hallucis brevis muscle" EXACT [Wikipedia:Flexor_hallucis_brevis_muscle] synonym: "m.flexor hallucis brevis" EXACT [FMA:37449] is_a: UBERON:0000366 ! flexor muscle relationship: part_of UBERON:0002387 ! pes xref: FMA:37449 ! flexor hallucis brevis synonym: "musculus flexor hallucis brevis" RELATED LATIN [Wikipedia:Flexor_hallucis_brevis_muscle] relationship: has_muscle_insertion UBERON:0001479 {source="dbpedia", notes="medial and lateral sesamoid bones of first metatarsal"} ! sesamoid bone relationship: has_muscle_insertion UBERON:0003650 {source="dbpedia", notes="medial and lateral sesamoid bones of first metatarsal"} ! metatarsal bone of digit 1 relationship: has_muscle_origin UBERON:0010721 {source="dbpedia", notes="plantar surface of cuneiform bones"} ! distal tarsal bone xref: http://upload.wikimedia.org/wikipedia/commons/5/58/Musculus_flexor_hallucis_brevis.png xref: SCTID:181730007 ! Entire flexor hallucis brevis muscle [Term] id: UBERON:0008245 name: pennate muscle def: "A pennate muscle (also called a penniform muscle) is a muscle with fascicles that attach obliquely (in a slanting position) to its tendon. These types of muscles generally allow better stabilization and force production but less flexibility. Individual muscle fibers are formed into bundles of fasciculi and these bundles of fasciculi are formed into bundles of fascicles which compose the entire muscle itself. In a pennate muscle, the fascicles will form an angle with its central tendon. If all the fascicles are on the same side of the tendon, the pennate muscle is called unipennate. Examples of this include certain muscles in the manus. If there are fascicles on both sides of the central tendon, the pennate muscle is called bipennate. The rectus femoris, a large muscle in the quadriceps, is typical. If the central tendon branches within a pennate muscle, the muscle is called multipennate, as seen in the deltoid muscle in the shoulder." [Wikipedia:Pennate_muscle] comment: note the FMA class does not denote a muscle organ. todo: add child classes xref: Wikipedia:Pennate_muscle ! pennate muscle xref: FMA:74993 ! pennate muscle is_a: UBERON:0001630 ! muscle organ relationship: innervated_by UBERON:0001267 {source="dbpedia"} ! femoral nerve relationship: has_muscle_antagonist UBERON:0002463 {source="dbpedia"} ! hamstring muscle relationship: has_muscle_origin UBERON:0001269 {source="dbpedia", notes="anterior inferior iliac spine and the exterior surface of the bony ridge which forms the iliac portion of the acetabulum"} ! acetabular part of hip bone xref: http://upload.wikimedia.org/wikipedia/commons/1/14/Rectus_femoris.png [Term] id: UBERON:0000372 name: extensor digitorum brevis def: "a muscle on the upper surface of the foot that helps extend digits 2 through 4." [Wikipedia:Extensor_digitorum_brevis_muscle] synonym: "extensor digitorum brevis muscle" EXACT [] xref: BTO:0001337 xref: FMA:51140 ! Extensor digitorum brevis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Gray441.png/200px-Gray441.png xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Gray1241.png/200px-Gray1241.png is_a: UBERON:0000311 {source="BTO"} ! extensor muscle relationship: part_of UBERON:0002387 ! pes synonym: "musculus extensor digitorum brevis" RELATED LATIN [Wikipedia:Extensor_digitorum_brevis_muscle] relationship: has_muscle_insertion UBERON:0003221 {source="dbpedia", notes="proximal dorsal region of middle phalanges 2 3 and 4"} ! phalanx relationship: has_muscle_origin UBERON:0001450 {source="dbpedia", notes="dorsal surface of calcaneus"} ! calcaneus xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray441.png [Term] id: UBERON:0001386 name: extensor digitorum longus def: "The Extensor digitorum longus is a pennate muscle, situated at the lateral part of the front of the leg. [WP,unvetted]." [Wikipedia:Extensor_digitorum_longus_muscle] subset: uberon_slim synonym: "extensor digitorum longus muscle" EXACT [BTO:0000436] synonym: "toe extensor" EXACT [HP:0011916] synonym: "toe extensor muscle" EXACT [] xref: BTO:0000436 xref: FMA:22534 ! Extensor digitorum longus xref: MA:0002295 ! extensor digitorum longus xref: ncithesaurus:Extensor_Digitorum_Longus ! Extensor Digitorum Longus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Gray1241.png/200px-Gray1241.png is_a: UBERON:0000311 {source="BTO"} ! extensor muscle relationship: part_of UBERON:0000978 ! leg relationship: innervated_by UBERON:0001324 {source="dbpedia"} ! common fibular nerve synonym: "musculus extensor digitorum longus" RELATED LATIN [Wikipedia:Extensor_digitorum_longus_muscle] relationship: has_muscle_insertion UBERON:0001449 {source="dbpedia", notes="Dorsal surface; middle and distal phalanges of lateral four digits"} ! phalanx of pes relationship: has_muscle_origin UBERON:0009991 {source="dbpedia", notes="Anterior lateral condyle of tibia anterior shaft of fibula and superior of interosseous membrane"} ! lateral condyle of tibia relationship: has_muscle_origin UBERON:0000979 {source="dbpedia", notes="Anterior lateral condyle of tibia anterior shaft of fibula and superior of interosseous membrane"} ! tibia relationship: has_muscle_origin UBERON:0001446 {source="dbpedia", notes="Anterior lateral condyle of tibia anterior shaft of fibula and superior of interosseous membrane"} ! fibula xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1241.png xref: UMLS:C0224464 [Term] id: UBERON:0007612 name: extensor digitorum communis def: "A muscle on the back of the forearm that extends the fingers and wrist." [BTO:0001343, Wikipedia:Extensor_digitorum_muscle] synonym: "extensor communis" RELATED [] synonym: "extensor digitorum" EXACT [FMA:38500] synonym: "extensor digitorum communis muscle" EXACT [] xref: BTO:0001343 ! extensor digitorum communis xref: MA:0002293 ! extensor digitorum communis xref: FMA:38500 ! extensor digitorum xref: ncithesaurus:Extensor_Digitorum_Communis ! Extensor Digitorum Communis is_a: UBERON:0011024 {source="Wikipedia"} ! extrinsic extensor muscle of manus relationship: has_muscle_antagonist UBERON:0001523 {source="dbpedia"} ! flexor digitorum profundus relationship: has_muscle_antagonist UBERON:0003222 {source="dbpedia"} ! flexor digitorum superficialis synonym: "musculus extensor digitorum" RELATED LATIN [Wikipedia:Extensor_digitorum_muscle] relationship: has_muscle_insertion UBERON:0004300 {source="dbpedia", notes="extensor expansion of middle and distal phalanges of the 2nd 3rd 4th and 5th fingers"} ! distal phalanx xref: http://upload.wikimedia.org/wikipedia/commons/e/e9/Extensor_digitorum_muscle.png xref: UMLS:C1707982 [Term] id: UBERON:0007613 name: extensor digitorum lateralis muscle comment: Origin distal to extensor digitorum communis. The part of this muscle that gives a tendon to the 5th digit is comparable to the extensor digiti quinti proprius of the human [ISBN10:9780716717553] xref: MA:0002294 ! extensor digitorum lateralis synonym: "extensor digitorum lateralis" EXACT [MA:0002294] xref: ncithesaurus:Extensor_Digitorum_Lateralis ! Extensor Digitorum Lateralis is_a: UBERON:0011024 {source="Wikipedia"} ! extrinsic extensor muscle of manus relationship: has_muscle_insertion UBERON:0003639 {source="ISBN10:9780716717553"} ! manual digit 5 phalanx relationship: never_in_taxon NCBITaxon:9606 {source="ISBN10:9780716717553"} ! Homo sapiens xref: UMLS:C1707983 [Term] id: UBERON:0007614 name: extensor digiti minimi muscle def: "The extensor minimi digiti (extensor digiti quinti proprius) is a slender muscle of the forearm, placed on the ulnar side of the Extensor digitorum communis, with which it is generally connected. It arises from the common Extensor tendon by a thin tendinous slip, from the intermuscular septa between it and the adjacent muscles. Its tendon runs through a compartment of the dorsal carpal ligament behind the distal radio-ulnar joint, then divides into two as it crosses the manus, and finally joins the expansion of the Extensor digitorum communis tendon on the dorsum of the first phalanx of the little finger[WP]." [Wikipedia:Extensor_digiti_minimi_muscle, http://www.anatomyatlases.org/AnatomicVariants/MuscularSystem/Text/E/14Extensor.shtml] comment: The tendon of insertion is sometimes divided and gives a slip to the fourth digit. An ulnar slip has been observed to end on the base of the fifth metacarpal, thus exactly reproducing the arrangement of the serially homologous slip known as peroneus tertius in the leg. The muscle may be absent in rare cases, but fusion with extensor digitorum is frequent, in which case the tendon comes from the common extensor. synonym: "extensor digiti minimi" RELATED [Wikipedia:Extensor_digiti_minimi_muscle] synonym: "extensor digiti minimi %28hand%29" RELATED [Wikipedia:Extensor_digiti_minimi_muscle] synonym: "extensor digiti quinti proprius" RELATED [Wikipedia:Extensor_digiti_minimi_muscle, http://www.anatomyatlases.org/AnatomicVariants/MuscularSystem/Text/E/14Extensor.shtml] synonym: "musculus extensor digiti minimi" RELATED LATIN [Wikipedia:Extensor_digiti_minimi_muscle] xref: FMA:38503 ! extensor digiti minimi xref: SCTID:361819009 ! Entire extensor digiti minimi muscle is_a: UBERON:0011024 {source="Wikipedia"} ! extrinsic extensor muscle of manus relationship: has_muscle_origin UBERON:0006807 {source="dbpedia", notes="the anterior portion of the lateral epicondyle of the humerus"} ! ectepicondyle of humerus relationship: has_muscle_insertion UBERON:0004331 {source="dbpedia", notes="at the extensor expansion located at the base of the proximal phalanx of digit V on the dorsal side"} ! proximal phalanx of manual digit 5 xref: http://upload.wikimedia.org/wikipedia/commons/1/15/Gray424.png [Term] id: UBERON:0011024 ! extrinsic extensor muscle of manus name: extrinsic extensor muscle of manus def: "The extrinsic extensor muscles of the hand are located in the back of the forearm and have long tendons connecting them to bones in the hand, where they exert their action." [Wikipedia:Extrinsic_extensor_muscles_of_the_hand] synonym: "extrinsic extensor muscle of hand" EXACT [Wikipedia:Extrinsic_extensor_muscles_of_the_hand] intersection_of: UBERON:0000311 ! extensor muscle intersection_of: part_of UBERON:0002386 ! forelimb zeugopod intersection_of: has_muscle_insertion UBERON:0005897 ! manus bone [Term] id: UBERON:0011867 ! extensor carpi radialis muscle name: extensor carpi radialis muscle synonym: "extensor carpi radialis" EXACT [] is_a: UBERON:0011024 ! extrinsic extensor muscle of manus relationship: innervated_by UBERON:0001492 ! radial nerve relationship: has_muscle_origin UBERON:0000976 ! humerus relationship: has_muscle_insertion UBERON:0002374 ! metacarpal bone xref: SCTID:276166006 ! Entire extensor carpi radialis muscle [Term] id: UBERON:0001524 name: extensor carpi radialis longus muscle def: "Extensor carpi radialis longus is one of the five main muscles that control movements at the wrist. This muscle is quite long, starting on the lateral side of the humerus, and attaching to the base of the second metacarpal bone (metacarpal of the index finger). [WP,unvetted]." [Wikipedia:Extensor_carpi_radialis_longus_muscle] synonym: "extensor carpi radialis longus" EXACT [MA:0002291] subset: uberon_slim xref: FMA:38494 ! Extensor carpi radialis longus xref: MA:0002291 ! extensor carpi radialis longus xref: ncithesaurus:Extensor_Carpi_Radialis_Longus ! Extensor Carpi Radialis Longus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/75/ECR-longus.png/200px-ECR-longus.png is_a: UBERON:0011867 ! extensor carpi radialis muscle relationship: has_muscle_origin UBERON:0004404 {source="dbpedia", notes="lateral supracondylar ridge"} ! distal epiphysis of humerus relationship: has_muscle_insertion UBERON:0003646 {source="dbpedia", notes="base"} ! metacarpal bone of digit 2 relationship: innervated_by UBERON:0001492 {source="dbpedia"} ! radial nerve synonym: "musculus extensor carpi radialis longus" RELATED LATIN [Wikipedia:Extensor_carpi_radialis_longus_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/7/75/ECR-longus.png xref: SCTID:244990000 ! Entire extensor carpi radialis longus muscle xref: UMLS:C0224266 [Term] id: UBERON:0001525 name: extensor carpi radialis brevis muscle def: "The Extensor carpi radialis brevis is shorter and thicker than the extensor carpi radialis longus. The longus muscle can be found above the distal end of the Extensor carpi radialis brevis. [WP,unvetted]." [Wikipedia:Extensor_carpi_radialis_brevis_muscle] subset: uberon_slim synonym: "extensor carpi radialis brevis" EXACT [MA:0002290] synonym: "musculus extensor carpi radialis brevis" EXACT LATIN [Wikipedia:Extensor_carpi_radialis_brevis_muscle] xref: FMA:38497 ! Extensor carpi radialis brevis xref: MA:0002290 ! extensor carpi radialis brevis xref: ncithesaurus:Extensor_Carpi_Radialis_Brevis ! Extensor Carpi Radialis Brevis is_a: UBERON:0011867 ! extensor carpi radialis muscle relationship: innervated_by UBERON:0001492 {source="dbpedia", notes="deep part"} ! radial nerve relationship: has_muscle_origin UBERON:0006807 {source="dbpedia"} ! ectepicondyle of humerus relationship: has_muscle_insertion UBERON:0003647 {source="dbpedia", notes="base"} ! metacarpal bone of digit 3 xref: SCTID:244991001 ! Entire extensor carpi radialis brevis muscle xref: UMLS:C0224267 [Term] id: UBERON:0001526 name: extensor carpi ulnaris muscle def: "Extensor carpi ulnaris is a muscle located in the forearm that acts to extend and adduct the wrist. Being an extensor muscle, extensor carpi ulnaris is on the posterior side of the forearm. [WP]." [Wikipedia:Extensor_carpi_ulnaris_muscle] comment: Taxon notes: Amphibians - def: "Muscle of the forearm: It shares a common origin with two other muscles of the forearm. It arises from the lateral epicondyle of the humerus by two tendons: the first one is in common with the m. extensor digitorum communis longus, and the second one is broad and in common with the m. epicondylocubitalis. It is pinnately attached to the dorsal surface of the distal carpal 5-4-3." [AAO:0010281]. Note that we make the insertion relationship a GCI until digit numbering issues are resolved synonym: "musculus extensor carpi ulnaris" EXACT [] synonym: "ECU muscle" EXACT [] synonym: "extensor carpi ulnaris" EXACT [] subset: uberon_slim xref: FMA:38506 ! Extensor carpi ulnaris xref: MA:0002292 ! extensor carpi ulnaris xref: AAO:0010281 ! M. extensor carpi ulnaris xref: ncithesaurus:Extensor_Carpi_Ulnaris ! Extensor Carpi Ulnaris xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Gray418.png/200px-Gray418.png is_a: UBERON:0011024 {source="Wikipedia"} ! extrinsic extensor muscle of manus relationship: innervated_by UBERON:0001492 {source="dbpedia", notes="deep part"} ! radial nerve relationship: has_muscle_origin UBERON:0006807 ! ectepicondyle of humerus relationship: has_muscle_origin UBERON:0001424 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! ulna relationship: has_muscle_insertion UBERON:0003649 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! metacarpal bone of digit 5 xref: SCTID:244992008 ! Entire extensor carpi ulnaris xref: http://upload.wikimedia.org/wikipedia/commons/2/25/Extensor_carpi_ulnaris_muscle.png property_value: external_definition "Muscle of the forearm: It shares a common origin with two other muscles of the forearm. It arises from the lateral epicondyle of the humerus by two tendons: the first one is in common with the m. extensor digitorum communis longus, and the second one is broad and in common with the m. epicondylocubitalis. It is pinnately attached to the dorsal surface of the distal carpal 5-4-3.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010281", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C0224272 [Term] id: UBERON:0000373 name: tapetum of corpus callosum def: "On either side of the corpus collosum, the fibers radiate in the white substance and pass to the various parts of the cerebral cortex; those curving forward from the genu into the frontal lobe constitute the forceps anterior, and those curving backward into the occipital lobe, the forceps posterior. Between these two parts is the main body of the fibers which constitute the tapetum and extend laterally on either side into the temporal lobe, and cover in the central part of the lateral ventricle. [Wikipedia via Greys]" [Wikipedia:Tapetum_of_corpus_callosum] comment: not to be confused with BTO:0001350 or GO:0048655-tapetal layer morphogenesis synonym: "tapetum" BROAD INCONSISTENT [FMA:77208] xref: FMA:77208 ! Tapetum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Gray733.png/200px-Gray733.png is_a: UBERON:0002316 ! white matter of neuraxis xref: SCTID:279312006 ! Entire tapetum of corpus callosum synonym: "tapetum corporis callosi" RELATED LATIN [Wikipedia:Tapetum_of_corpus_callosum] xref: http://upload.wikimedia.org/wikipedia/commons/a/aa/Gray733.png [Term] id: UBERON:0000375 name: mandibular nerve def: "the motor and sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the auricle, the external acoustic meatus, tympanic membrane, temporal region, the cheek, the skin overlying the mandible, the anterior portion of the tongue, the floor of the mouth, lower teeth and gingiva and transmits motor information from the muscles of mastication, the mylohyoid muscle and digastric muscle and the muscles tensor tympani and tensor veli palatini." [MP:0009800, Wikipedia:Mandibular_nerve] synonym: "inferior maxillary nerve" EXACT [FMA:52996] synonym: "mandibular division [V3]" EXACT [FMA:52996] synonym: "mandibular division [Vc]" EXACT [FMA:52996] synonym: "mandibular division of fifth cranial nerve" EXACT [FMA:52996] synonym: "mandibular division of trigeminal nerve [Vc; V3]" EXACT [FMA:52996] synonym: "mandibular nerve [V3]" EXACT [FMA:52996] synonym: "mandibular nerve [Vc]" EXACT [FMA:52996] synonym: "nervus mandibularis [Vc; V3]" EXACT [FMA:52996] synonym: "third division of fifth cranial nerve" EXACT [FMA:52996] synonym: "third division of trigeminal nerve" EXACT [FMA:52996] synonym: "trigeminal V nerve mandibular division" EXACT [MA:0001101] synonym: "nervus mandibularis" RELATED [BTO:0001375] synonym: "ramus mandibularis (ramus V3)" EXACT [AAO:0010688] xref: BTO:0001375 xref: FMA:52996 ! Mandibular nerve xref: ncithesaurus:Inferior_Maxillary_Nerve ! Inferior Maxillary Nerve xref: GAID:834 ! mandibular nerve xref: OpenCyc:Mx4rvcQKSpwpEbGdrcN5Y29ycA ! mandibular nerve xref: MA:0001101 ! trigeminal V nerve mandibular division xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray781.png/200px-Gray781.png xref: EHDAA2:0002086 ! trigeminal V nerve mandibular division xref: MESH:A08.800.800.120.760.500 ! mandibular nerve xref: VHOG:0001345 ! trigeminal V nerve mandibular division xref: AAO:0010688 ! ramus mandibularis (ramus V3) xref: AAO:0010703 ! ramus mandibularis V3 (main branch) is_a: UBERON:0000063 ! organ segment is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0001645 ! trigeminal nerve synonym: "nervus mandibularis [vc]" EXACT LATIN [FMA:TA, FMA:52996] synonym: "nervus mandibularis [v3]" EXACT LATIN [FMA:TA, FMA:52996] xref: SCTID:280212008 ! Entire mandibular nerve synonym: "n. mandibularis" RELATED LATIN [Wikipedia:Mandibular_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray781.png xref: UMLS:C0024695 [Term] id: UBERON:0000377 name: maxillary nerve def: "the sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses." [MP:0009799, Wikipedia:Maxillary_nerve] synonym: "maxillary division [V2]" EXACT [FMA:52724] synonym: "maxillary division [Vb]" EXACT [FMA:52724] synonym: "maxillary division of fifth cranial nerve" EXACT [FMA:52724] synonym: "maxillary division of trigeminal nerve (Vb; V2)" EXACT [FMA:52724] synonym: "maxillary nerve [V2]" EXACT [FMA:52724] synonym: "maxillary nerve [Vb]" EXACT [FMA:52724] synonym: "nervus maxillaris (Vb; V2)" EXACT [FMA:52724] synonym: "second division of fifth cranial nerve" EXACT [FMA:52724] synonym: "second division of trigeminal nerve" EXACT [FMA:52724] synonym: "trigeminal V nerve maxillary division" EXACT [MA:0001103] synonym: "nervus maxillaris" RELATED [BTO:0001378] synonym: "ramus maxillaris (ramus V2)" EXACT [AAO:0010670] xref: BTO:0001378 xref: FMA:52724 ! Maxillary nerve xref: MA:0001103 ! trigeminal V nerve maxillary division xref: GAID:836 ! maxillary nerve xref: OpenCyc:Mx4rvWNU9JwpEbGdrcN5Y29ycA ! maxillary nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a9/Gray779.png/200px-Gray779.png xref: EHDAA2:0002087 ! trigeminal V nerve maxillary division xref: MESH:A08.800.800.120.760.550 ! maxillary nerve xref: VHOG:0001346 ! trigeminal V nerve maxillary division xref: AAO:0010670 ! ramus maxillaris (ramus V2) is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0001645 ! trigeminal nerve synonym: "nervus maxillaris [vb]" EXACT LATIN [FMA:TA, FMA:52724] synonym: "nervus maxillaris [v2]" EXACT LATIN [FMA:TA, FMA:52724] xref: SCTID:280211001 ! Entire maxillary nerve synonym: "n. maxillaris" RELATED LATIN [Wikipedia:Maxillary_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray779.png property_value: external_definition "Medial ramus (sensory) of the trigeminal nerve.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010670", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of trunk maxillary-mandibularis (AAO:0010669)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010670", date_retrieved="2012-06-20"} [Term] id: UBERON:0013646 name: buccal nerve def: "The buccal nerve (also called the long buccal nerve) is a nerve in the face. It is a branch of the mandibular nerve (which is itself a branch of the trigeminal nerve) and transmits sensory information from skin over the buccal membrane (in general, the cheek) and from the second and third molar teeth." [Wikipedia:Buccal_nerve] synonym: "buccinator branch" RELATED [Wikipedia:Buccal_nerve] synonym: "long buccal nerve" RELATED [Wikipedia:Buccal_nerve] synonym: "buccinator nerve" EXACT [FMA:53066] synonym: "long buccal nerve" EXACT [FMA:53066] is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0000375 {source="FMA"} ! mandibular nerve xref: FMA:53066 ! buccal nerve xref: SCTID:280253000 ! Entire buccal nerve [Term] id: UBERON:0013647 name: lateral pterygoid nerve def: "External Pterygoid Nerve (or lateral pterygoid nerve): The nerve to the Pterygoideus externus frequently arises in conjunction with the buccinator nerve, but it may be given off separately from the anterior division of the mandibular nerve. It enters the deep surface of the muscle." [Wikipedia:Lateral_pterygoid_nerve] synonym: "external pterygoid nerve" RELATED [Wikipedia:Lateral_pterygoid_nerve] synonym: "branch of buccal nerve to lateral pterygoid" EXACT [FMA:53107] synonym: "nerve to lateral pterygoid" EXACT [FMA:53107] synonym: "nervus pterygoideus lateralis" EXACT [FMA:TA] is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0013646 {source="FMA"} ! buccal nerve xref: FMA:53107 ! lateral pterygoid nerve xref: SCTID:48852002 ! Lateral pterygoid nerve [Term] id: UBERON:0003273 name: skeletal muscle of tongue def: "A portion of skeletal muscle tissue that is part of a tongue [Automatically generated definition]." [OBOL:automatic] synonym: "skeletal muscle tissue of tongue" EXACT [OBOL:automatic] synonym: "tongue skeletal muscle" EXACT [OBOL:automatic] synonym: "tongue skeletal muscle tissue" EXACT [OBOL:automatic] xref: EHDAA:9146 ! skeletal muscle (also: UBERON:0001134 'skeletal muscle tissue') xref: VHOG:0001390 ! tongue skeletal muscle xref: ncithesaurus:Tongue_Skeletal_Muscle_Tissue ! Tongue Skeletal Muscle Tissue xref: MA:0001596 ! tongue skeletal muscle xref: EHDAA2:0002065 ! tongue skeletal muscle xref: EMAPA:17883 ! skeletal muscle of tongue of pharynx of foregut xref: EMAPA:18879 ! skeletal muscle of tongue of pharynx of gut intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0000378 ! tongue muscle relationship: develops_from UBERON:0005594 {source="ISBN10:1607950324"} ! head somite property_value: homology_notes "The lamprey head contains another group of muscles, the epi- and hypo-branchial muscles (EBM and HBM), derivatives of anterior trunk myotomes. (...) The origin and the migration pattern of HBM precursors are very similar to that of the gnathostome MPP, especially to that of the tongue muscle precursors. Other evidence of homology of lamprey HBM to the gnathostome tongue muscle is that HBM is innervated by the nerve termed the hypoglossal nerve based on its morphological position associated with the head/trunk interface. (...) The HBM-specific expression of the LampPax3/7 gene is consistent with the homology of this muscle to the gnathostome tongue muscle, or to the hypobranchial series as a whole (including the infrahyoid and possibly the diaphragm in mammals).[well established][VHOG]" xsd:string {external_class="VHOG:0001390", ontology="VHOG", source="DOI:10.1002/dvdy.20587 Kusakabe R\, Kuratani S\, Evolution and developmental patterning of the vertebrate skeletal muscles: perspectives from the lamprey. Developmental Dynamics (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: part_of UBERON:0004477 {source="reference_0000032"} ! tongue musculature xref: UMLS:C1710437 [Term] id: UBERON:0007367 name: surface of tongue synonym: "tongue surface" EXACT [FMA:54647] xref: FMA:54647 ! Surface of tongue intersection_of: UBERON:0006984 ! anatomical surface intersection_of: part_of UBERON:0001723 ! tongue xref: SCTID:314870004 ! Tongue surface region def: "An anatomical surface that is part of a tongue." [OBOL:automatic] [Term] id: UBERON:0007371 name: superior surface of tongue synonym: "dorsal surface of tongue" EXACT [FMA:54646] xref: FMA:54646 ! Superior surface of tongue is_a: UBERON:0007367 ! surface of tongue [Term] id: UBERON:0007373 name: inferior surface of tongue synonym: "ventral surface of tongue" EXACT [FMA:54648] synonym: "ventrum linguae" EXACT [] xref: FMA:54648 ! Inferior surface of tongue is_a: UBERON:0007367 ! surface of tongue xref: SCTID:362100003 ! Entire inferior surface of tongue [Term] id: UBERON:0000379 name: tracheal mucosa synonym: "Mucous membrane of trachea" EXACT [FMA:7471] synonym: "Tracheal mucous membrane" EXACT [FMA:7471] synonym: "Tunica mucosa (tracheae)" EXACT [FMA:7471] synonym: "mucosa of organ of trachea" EXACT [OBOL:automatic] synonym: "mucosa of organ of windpipe" EXACT [OBOL:automatic] synonym: "mucosa of trachea" EXACT [OBOL:automatic] synonym: "mucosa of windpipe" EXACT [OBOL:automatic] synonym: "mucous membrane of trachea" EXACT [OBOL:automatic] synonym: "mucous membrane of windpipe" EXACT [OBOL:automatic] synonym: "organ mucosa of trachea" EXACT [OBOL:automatic] synonym: "organ mucosa of windpipe" EXACT [OBOL:automatic] synonym: "trachea mucosa" EXACT [OBOL:automatic] synonym: "trachea mucosa of organ" EXACT [OBOL:automatic] synonym: "trachea mucous membrane" EXACT [OBOL:automatic] synonym: "trachea organ mucosa" EXACT [OBOL:automatic] synonym: "windpipe mucosa" EXACT [OBOL:automatic] synonym: "windpipe mucosa of organ" EXACT [OBOL:automatic] synonym: "windpipe mucous membrane" EXACT [OBOL:automatic] synonym: "windpipe organ mucosa" EXACT [OBOL:automatic] xref: BTO:0001390 xref: FMA:7471 ! Mucosa of trachea is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001005 ! trachea synonym: "tunica mucosa tracheae" EXACT LATIN [FMA:TA, FMA:7471] xref: SCTID:660006 ! Tracheal mucous membrane def: "A mucosa that is part of a respiratory airway." [OBOL:automatic] [Term] id: UBERON:0000380 name: obsolete tuber comment: undefined in FMA. BTO and MIAA refers to plant structure only xref: BTO:0001400 consider: FMA:75430 ! Tuber consider: EFO:0001015 ! tuber xref: OpenCyc:Mx4raeDj5Cw8QdiT7e8pb2JzAA ! tuber is_obsolete: true [Term] id: UBERON:0000381 name: urinary bladder detrusor smooth muscle def: "bundles of smooth muscle fibers forming the muscular wall of the urinary bladder, which are arranged in a longitudinal and a circular layer and, on contraction, serve to expel urine[MP]." [MP:0011774, Wikipedia:Detrusor_urinae_muscle] synonym: "detrusor muscle" EXACT [BTO:0001453] synonym: "detrusor muscle of bladder" EXACT [EMAPA:28637] synonym: "detrusor urinae muscle" EXACT [Wikipedia:Detrusor_urinae_muscle] synonym: "muscularis propria of the urinary bladder" EXACT [Wikipedia:Detrusor_urinae_muscle] synonym: "muscularis propria" BROAD [Wikipedia:Detrusor_urinae_muscle, ncithesaurus:Muscularis_Propria] synonym: "urinary bladder detrussor smooth muscle" EXACT [MA:0001698] synonym: "detrusor" EXACT [FMA:68018] synonym: "musculus detrusor vesicae urinariae" RELATED LATIN [Wikipedia:Detrusor_urinae_muscle] synonym: "urinary bladder detrusor muscle" EXACT [MA:0001698] xref: BTO:0001453 ! detrusor xref: FMA:68018 ! detrusor xref: EMAPA:28637 ! detrusor muscle of bladder xref: MA:0001698 ! urinary bladder detrussor smooth muscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/57/Illu_bladder.jpg/200px-Illu_bladder.jpg xref: ncithesaurus:Muscularis_Propria ! muscularis propria xref: SCTID:279414008 ! Entire detrusor muscle of urinary bladder is_a: UBERON:0001135 ! smooth muscle tissue relationship: part_of UBERON:0012378 {source="FMA"} ! muscle layer of bladder relationship: has_function_in GO:0060073 ! micturition relationship: has_muscle_insertion UBERON:0000996 {gci_relation="part_of", gci_filler="UBERON:0003100", notes="female", source="dbpedia-modified"} ! vagina relationship: has_muscle_insertion UBERON:0002367 {gci_relation="part_of", gci_filler="UBERON:0003101", notes="male", source="dbpedia-modified", source="dbpedia-modified"} ! prostate gland relationship: has_muscle_origin UBERON:0001275 {source="dbpedia", notes="posterior surface of the body of the pubis"} ! pubis xref: http://upload.wikimedia.org/wikipedia/commons/5/57/Illu_bladder.jpg [Term] id: UBERON:0000385 name: obsolete labial gland comment: the label 'labial gland' refers to two distinct classes. From the BTO def: 1. One of the small tubular mucous and serous glands lying beneath the mucous membrane of the lips.n2. A salivary gland, or modification thereof, opening at the base of the labium in certain insects. synonym: "Labial glands" EXACT [FMA:71613] synonym: "Labial glands set" EXACT [FMA:71613] xref: BTO:0001548 consider: FMA:71613 ! Set of labial glands consider: HAO:0000449 ! labial gland is_obsolete: true synonym: "glandulae labiales" EXACT LATIN [FMA:TA, FMA:71613] [Term] id: UBERON:0000387 name: meniscus def: "crescent-shaped fibrocartilaginous structure present in the knee, acromioclavicular, sternoclavicular, and temporomandibular joints[2] that, in contrast to articular disks, only partly divides a joint cavity.[3] A small meniscus also occurs in the radio-carpal joint." [Wikipedia:Meniscus_(anatomy)] synonym: "articular disc" EXACT [FMA:76690] xref: BTO:0001592 xref: FMA:76690 ! Articular disc xref: ncithesaurus:Meniscus ! Meniscus xref: galen:Meniscus ! meniscus xref: EV:0100145 ! meniscus is_a: UBERON:0000061 ! anatomical structure xref: UMLS:C0224498 [Term] id: UBERON:0000389 name: lens cortex synonym: "cortex of lens" EXACT [FMA:58970] xref: BTO:0001632 xref: FMA:58970 ! Cortex of lens xref: MESH:A09.371.509.225 ! crystalline lens cortex is_a: UBERON:0001851 ! cortex relationship: part_of UBERON:0000965 ! lens xref: SCTID:280626006 ! Entire cortex of lens [Term] id: UBERON:0000390 name: lens nucleus def: "The core of the crystalline lens, surrounded by the cortex." [BTO:0001633] comment: editor note: needs checked; cf nucleus in GO synonym: "nucleus of lens" EXACT [FMA:58971] xref: BTO:0001633 xref: FMA:58971 ! Nucleus of lens xref: MESH:A09.371.509.670 ! crystalline lens nucleu is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000965 ! lens xref: SCTID:280628007 ! Entire nucleus of lens [Term] id: UBERON:0000392 name: longissimus muscle def: "The longissimus is the muscle lateral to the semispinalis. It is the longest subdivision of the sacrospinalis that extends forward into the transverse processes of the posterior cervical vertebrae. [WP,unvetted]." [Wikipedia:Longissimus] synonym: "musculus longissimus" EXACT [BTO:0001648] synonym: "intermediate column of erector spinae" RELATED [] xref: BTO:0001648 xref: FMA:77178 ! longissimus synonym: "longissimus" EXACT [FMA:77178] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Longissimus.png/200px-Longissimus.png is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column relationship: part_of UBERON:0002462 {source="BTO"} ! erector spinae relationship: innervated_by UBERON:0006839 {source="dbpedia"} ! posterior ramus of spinal nerve relationship: has_muscle_origin UBERON:0001077 {source="dbpedia"} ! transverse process of vertebra relationship: has_muscle_insertion UBERON:0001077 {source="dbpedia"} ! transverse process of vertebra synonym: "musculus longissimus" RELATED LATIN [Wikipedia:Longissimus] xref: http://upload.wikimedia.org/wikipedia/commons/1/1f/Longissimus.png xref: SCTID:244858006 ! Entire longissimus muscle [Term] id: UBERON:0001401 name: longissimus thoracis muscle def: "The longissimus is the muscle lateral to the semispinalis. It is the longest subdivision of the sacrospinalis that extends forward into the transverse processes of the posterior cervical vertebrae. [WP,unvetted]." [Wikipedia:Longissimus#Longissimus_thoracis] comment: Editor's note: TODO - add logical definition to determine if AAO class belongs here. Classified as erector spinae in AAO subset: uberon_slim synonym: "longissimus dorsi" RELATED [BTO:0001651] synonym: "musculus longissimus thoracis" RELATED [BTO:0001651] xref: FMA:22709 ! Longissimus thoracis xref: MA:0002339 ! longissimus thoracis synonym: "longissimus thoracis" EXACT [MA:0002339] xref: ncithesaurus:Longissimus_Thoracis ! Longissimus Thoracis xref: BTO:0001651 ! longissimus thoracis xref: AAO:0010775 ! M. longissimus dorsi xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Longissimus.png/200px-Longissimus.png is_a: UBERON:0000392 {source="FMA"} ! longissimus xref: SCTID:244859003 ! Entire longissimus thoracis muscle property_value: external_definition "Epaxial muscle which originates on the antero-lateral urostyle and inserts variably along the neural spines and transverse processes of the presacral vertebrae to the exoccipital bone.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010775", date_retrieved="2012-06-20", source="AAO:MEJ"} xref: UMLS:C0224307 [Term] id: UBERON:0001402 name: longissimus cervicis muscle def: "The longissimus is the muscle lateral to the semispinalis. It is the longest subdivision of the sacrospinalis that extends forward into the transverse processes of the posterior cervical vertebrae. [WP,unvetted]." [Wikipedia:Longissimus#Longissimus_cervicis] subset: uberon_slim synonym: "musculus longissimus cervicis" RELATED [BTO:0001650] xref: FMA:22711 ! Longissimus cervicis xref: MA:0002337 ! longissimus cervicis synonym: "longissimus cervicis" EXACT [MA:0002337] xref: ncithesaurus:Longissimus_Cervicis ! Longissimus Cervicis xref: BTO:0001650 ! longissimus cervicis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Longissimus.png/200px-Longissimus.png is_a: UBERON:0000392 ! longissimus xref: SCTID:244860008 ! Entire longissimus cervicis muscle xref: UMLS:C0224308 [Term] id: UBERON:0001403 name: longissimus capitis def: "The longissimus is the muscle lateral to the semispinalis. It is the longest subdivision of the sacrospinalis that extends forward into the transverse processes of the posterior cervical vertebrae. [WP,unvetted]." [Wikipedia:Longissimus#Longissimus_capitis] subset: uberon_slim synonym: "musculus longissimus capitis" RELATED [BTO:0001649] synonym: "trachelomastoid muscle" RELATED [BTO:0001649] xref: FMA:22714 ! Longissimus capitis xref: MA:0002336 ! longissimus capitis xref: ncithesaurus:Longissimus_Capitis ! Longissimus Capitis xref: BTO:0001649 ! longissimus capitis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Longissimus.png/200px-Longissimus.png xref: SCTID:244861007 ! Entire longissimus capitis muscle is_a: UBERON:0000392 ! longissimus relationship: has_muscle_insertion UBERON:0011220 {source="Wikipedia:Mastoid_process"} ! mastoid process of temporal bone xref: UMLS:C0224309 [Term] id: UBERON:0011219 name: longissimus lumborum muscle def: "Lumbar muscle that extends and rotates the vertebral column." [BTO:0001925] synonym: "musculus longissimus lumborum" RELATED [BTO:0001925] is_a: UBERON:0000392 ! longissimus xref: BTO:0001925 ! longissimus lumborum xref: MA:0002338 ! longissimus lumborum xref: ncithesaurus:Longissimus_Lumborum ! longissimus lumborum synonym: "longissimus lumborum" EXACT [MA:0002338] xref: UMLS:C1708736 [Term] id: UBERON:0011465 name: longissimus atlantis muscle def: "A muscle that runs beneath the longissimus capitis and inserts on the wing of the atlas " [http://de.wikipedia.org/wiki/Musculus_longissimus] comment: present in horses and dogs is_a: UBERON:0000392 ! longissimus relationship: attaches_to UBERON:0001092 ! cervical vertebra 1 xref: MA:0002335 ! longissimus atlantis synonym: "longissimus atlantis" EXACT [MA:0002335] [Term] id: UBERON:0000397 name: colonic epithelium def: "An epithelium that is part of a colon [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "Colon epithelium" EXACT [FMA:17302] synonym: "colon epithelial tissue" EXACT [OBOL:automatic] synonym: "colon epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of colon" EXACT [OBOL:automatic] synonym: "epithelial tissue of large bowel" EXACT [OBOL:automatic] synonym: "epithelium of colon" EXACT [OBOL:automatic] synonym: "epithelium of large bowel" EXACT [OBOL:automatic] synonym: "large bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "large bowel epithelium" EXACT [OBOL:automatic] synonym: "posterior intestine epithelium" EXACT [ZFA:0005128] xref: BTO:0001709 xref: FMA:17302 ! Epithelium of colon xref: ZFA:0005128 ! posterior intestine epithelium is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001155 ! colon xref: SCTID:42978003 ! Colonic epithelium xref: TAO:0005128 ! posterior intestine epithelium property_value: external_definition "Intestinal epithelium which lines the lumen of the posterior intestine.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005128", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0008342 name: intestinal villus of duodenum def: "An intestinal villus in the duodenum." [OBOL:automatic] intersection_of: UBERON:0001213 ! intestinal villus intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0000320 ! duodenal mucosa xref: FMA:63300 ! intestinal villus of duodenum [Term] id: UBERON:0008343 name: intestinal villus of jejunum def: "An intestinal villus in the jejunum." [OBOL:automatic] intersection_of: UBERON:0001213 ! intestinal villus intersection_of: part_of UBERON:0002115 ! jejunum relationship: part_of UBERON:0000399 ! jejunal mucosa xref: FMA:63301 ! intestinal villus of jejunum [Term] id: UBERON:0008344 name: intestinal villus of ileum def: "An intestinal villus in the ileum." [OBOL:automatic] intersection_of: UBERON:0001213 ! intestinal villus intersection_of: part_of UBERON:0002116 ! ileum relationship: part_of UBERON:0000331 ! ileal mucosa xref: FMA:63302 ! intestinal villus of ileum [Term] id: UBERON:0008345 name: ileal epithelium synonym: "epithelium of ileum" EXACT [FMA:17233] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002116 ! ileum relationship: part_of UBERON:0008344 {source="FMA"} ! intestinal villus of ileum xref: FMA:17233 ! ileal epithelium xref: SCTID:47046000 ! Ileal epithelium def: "An epithelium that is part of a ileum." [OBOL:automatic] [Term] id: UBERON:0000399 name: jejunal mucosa alt_id: UBERON:0003349 def: "A mucosa that is part of a jejunum [Automatically generated definition]." [OBOL:automatic] synonym: "jejunal mucous membrane" EXACT [FMA:14949] synonym: "jejunum mucosa" EXACT [FMA:14949] synonym: "mucosa of jejunum" EXACT [FMA:14949] synonym: "jejunum mucosa of organ" EXACT [OBOL:automatic] synonym: "jejunum mucous membrane" EXACT [OBOL:automatic] synonym: "jejunum organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of jejunum" EXACT [OBOL:automatic] synonym: "mucous membrane of jejunum" EXACT [OBOL:automatic] synonym: "organ mucosa of jejunum" EXACT [OBOL:automatic] xref: BTO:0001742 xref: FMA:14949 ! Mucosa of jejunum xref: EMAPA:27109 ! mucosa of jejunum of midgut xref: EMAPA:27347 ! mucosa of jejunum of gut is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002115 ! jejunum xref: SCTID:362151009 ! Entire jejunal mucous membrane [Term] id: UBERON:0000400 name: jejunal epithelium synonym: "epithelium of jejunum" EXACT [] xref: BTO:0001743 xref: FMA:17232 ! Jejunal epithelium is_a: UBERON:0001902 {source="BTO"} ! epithelium of small intestine intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002115 ! jejunum relationship: part_of UBERON:0008343 {source="FMA"} ! intestinal villus of jejunum xref: SCTID:57300004 ! Jejunal epithelium def: "An epithelium that is part of a jejunum." [OBOL:automatic] [Term] id: UBERON:0008346 name: duodenal epithelium synonym: "epithelium of duodenum" EXACT [FMA:17231] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0008342 {source="FMA"} ! intestinal villus of duodenum xref: FMA:17231 ! duodenal epithelium xref: SCTID:66036002 ! Duodenal epithelium def: "An epithelium that is part of a duodenum." [OBOL:automatic] [Term] id: UBERON:0000401 name: mandibular ramus def: "The ramus of the mandible (perpendicular portion) is quadrilateral in shape, and has two surfaces, four borders, and two processes[WP]." [Wikipedia:Ramus_of_the_mandible] synonym: "lower ramus" RELATED [Wikipedia:Ramus_of_the_mandible] synonym: "rami mandibulae" RELATED PLURAL [Wikipedia:Ramus_of_the_mandible] synonym: "ramus mandibulae" RELATED PLURAL [Wikipedia:Ramus_of_the_mandible] synonym: "ramus of mandible" EXACT [FMA:52828] synonym: "mandible ramus" EXACT [MA:0002815] xref: BTO:0001751 xref: FMA:52828 ! Ramus of mandible xref: EMAPA:25100 ! ramus xref: MA:0002815 ! mandible ramus is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001684 ! mandible xref: SCTID:361739000 ! Entire ramus of mandible synonym: "ramus mandibulae" RELATED LATIN [Wikipedia:Ramus_of_the_mandible] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png [Term] id: UBERON:0011342 ! surface of mandible name: surface of mandible synonym: "mandibular surface" EXACT [FMA:57558] is_a: UBERON:0006984 ! anatomical surface relationship: part_of UBERON:0001684 ! mandible xref: FMA:57558 ! surface of mandible [Term] id: UBERON:0011343 name: medial surface of mandible synonym: "medial surface of mandibular ramus" NARROW [FMA:59464] is_a: UBERON:0011342 ! surface of mandible xref: FMA:59464 ! medial surface of ramus of mandible synonym: "medial surface of ramus of mandible" EXACT [FMA:59464] [Term] id: UBERON:0011344 name: lateral surface of mandible synonym: "lateral surface of mandibular ramus" BROAD [FMA:59463] is_a: UBERON:0011342 ! surface of mandible xref: FMA:59463 ! lateral surface of ramus of mandible synonym: "lateral surface of ramus of mandible" EXACT [FMA:59463] [Term] id: UBERON:0000403 name: scalp def: "The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendonous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL)." [MESH:A01.456.810, Wikipedia:Scalp] xref: BTO:0001809 xref: FMA:46494 ! Scalp xref: GAID:80 ! scalp xref: galen:Scalp ! scalp xref: OpenCyc:Mx4rwNtaz5wpEbGdrcN5Y29ycA ! scalp xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/eb/Double_cowlick.jpg/200px-Double_cowlick.jpg xref: MESH:A01.456.810 ! scalp is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0000033 {source="BTO"} ! head relationship: overlaps UBERON:0002097 {source="BTO"} ! skin of body xref: SCTID:181480002 ! Entire scalp xref: ncithesaurus:Scalp ! scalp synonym: "scalpus" RELATED LATIN [Wikipedia:Scalp] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Layers_of_the_scalp_and_meninges.png xref: UMLS:C0036270 [Term] id: UBERON:0000407 name: sympathetic trunk def: "One of a a paired bundle of nerve fibers that run from the base of the skull to the coccyx." [Wikipedia:Sympathetic_trunk] synonym: "sympathetic chain" EXACT [FMA:6258] synonym: "gangliated cord" EXACT [Wikipedia:Sympathetic_trunk] synonym: "sympathetic ganglionic chain" EXACT [Wikipedia:Sympathetic_trunk] xref: BTO:0001834 xref: FMA:6258 ! Sympathetic trunk xref: XAO:0000211 ! sympathetic chain xref: EV:0100374 ! sympathetic chain is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0000013 ! sympathetic nervous system xref: AAO:0010791 ! sympathetic chain xref: SCTID:181099004 ! Entire sympathetic trunk synonym: "truncus sympathicus" RELATED LATIN [Wikipedia:Sympathetic_trunk] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray847.png relationship: in_lateral_side_of UBERON:0000013 {source="FMA-abduced-lr"} ! sympathetic nervous system [Term] id: UBERON:0000408 name: vertebral ganglion synonym: "Intermediate ganglion" EXACT [FMA:6572] xref: BTO:0001835 xref: FMA:6572 ! Vertebral ganglion is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001991 ! cervical ganglion xref: SCTID:176596009 ! Entire vertebral ganglion [Term] id: UBERON:0000409 name: serous gland def: "Serous glands contain serous acini, a grouping of serous cells that secrete a fluid, isotonic with blood plasma, that contains enzymes such as alpha amylase. Serous glands are most common in the parotid gland and lacrimal gland but are also present in the submandibular gland and, to a far lesser extent, the sublingual gland." [Wikipedia:Serous_gland] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png xref: BTO:0001837 xref: FMA:62889 ! Serous gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: has_part CL:0000313 ! serous secreting cell relationship: has_part UBERON:0013232 ! serous acinus subset: organ_slim property_value: external_definition "glands that secrete watery albuminous material that often contains enzymes[MP:0008052]." xsd:string {source="MP:0008052"} [Term] id: UBERON:0013232 name: serous acinus intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0000409 ! serous gland relationship: has_part CL:0000313 ! serous secreting cell xref: FMA:86279 ! serous acinus [Term] id: UBERON:0000410 name: bronchial mucosa def: "A mucosa that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "Mucous membrane of bronchus" EXACT [FMA:62652] synonym: "bronchi mucosa" EXACT [OBOL:automatic] synonym: "bronchi mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchi mucous membrane" EXACT [OBOL:automatic] synonym: "bronchi organ mucosa" EXACT [OBOL:automatic] synonym: "bronchial trunk mucosa" EXACT [OBOL:automatic] synonym: "bronchial trunk mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchial trunk mucous membrane" EXACT [OBOL:automatic] synonym: "bronchial trunk organ mucosa" EXACT [OBOL:automatic] synonym: "bronchus mucosa" EXACT [OBOL:automatic] synonym: "bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bronchi" EXACT [OBOL:automatic] synonym: "mucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "mucosa of bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchi" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchial trunk" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchi" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchial trunk" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchi" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchus" EXACT [OBOL:automatic] xref: BTO:0001846 xref: FMA:62652 ! Mucosa of bronchus is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002185 ! bronchus synonym: "tunica mucosa bronchi" EXACT LATIN [FMA:TA, FMA:62652] xref: SCTID:30802009 ! Mucous membrane of bronchus [Term] id: UBERON:0000414 name: mucous gland def: "A gland that secretes mucus[cjm]. In humans, these are found in several different parts of the body, typically stain lighter than serous glands during standard histological preparation. Most are multicellular, but goblet cell are single-celled glands. [WP,modified]." [Wikipedia:Mucous_gland] property_value: taxon_notes "In frogs and salamanders, this is the smaller of the two types of gland, the other being the granular (poison) gland. In these species the mucous gland is a cluster of cells that release secretion into a common duct[Kardong]" xsd:string {scope="NCBITaxon:8292", source="Kardong"} synonym: "mucus gland" RELATED [] synonym: "glandula mucosa" RELATED [BTO:0001979] synonym: "muciparous gland" RELATED [BTO:0001979] xref: BTO:0001979 xref: FMA:62888 ! Mucous gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Gray1021.png/200px-Gray1021.png intersection_of: UBERON:0002365 ! exocrine gland intersection_of: capable_of GO:0070254 ! mucus secretion relationship: secretes UBERON:0000912 ! mucus relationship: has_part CL:0000319 ! mucus secreting cell xref: AAO:0010601 ! mucous gland subset: organ_slim synonym: "glandula mucosa" RELATED LATIN [Wikipedia:Mucous_gland] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png [Term] id: UBERON:0000415 name: artery wall def: "An anatomical wall that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "Arterial wall" EXACT [FMA:14155] synonym: "wall of artery" EXACT [FMA:14155] xref: BTO:0002009 xref: FMA:14155 ! Wall of artery xref: galen:ArterialWall is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0001637 ! artery [Term] id: UBERON:0000418 name: obsolete tubercle is_obsolete: true [Term] id: UBERON:0000420 name: myoepithelium def: "An epithelium consisting of myopethelial cells, which are contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament[CL]." [CL:0000185, Wikipedia:Myoepithelial_cell] synonym: "myo-epithelium" EXACT [FMA:67805] xref: BTO:0002308 xref: FMA:67805 ! Myo-epithelium intersection_of: UBERON:0000488 ! atypical epithelium intersection_of: has_part CL:0000185 ! myoepithelial cell synonym: "myoepitheliocytus" RELATED LATIN [Wikipedia:Myoepithelial_cell] [Term] id: UBERON:0008974 ! apocrine gland name: apocrine gland def: "A gland whose discharged secretion contains part of the secreting cells." [BTO:0001162, Wikipedia:Apocrine] synonym: "true apocrine gland" EXACT [] is_a: UBERON:0002530 {source="BTO"} ! gland xref: SCTID:361698000 ! Entire apocrine gland xref: BTO:0001162 ! apocrine gland subset: organ_slim property_value: has_relational_adjective "apocrine" xsd:string [Term] id: UBERON:0010243 name: merocrine gland def: "One in which the secretory cells maintain their integrity throughout the secretory cycle." [BTO:0002324, Wikipedia:Merocrine] intersection_of: UBERON:0002530 ! gland intersection_of: capable_of GO:0006887 ! exocytosis disjoint_from: UBERON:0008974 {source="cjm"} ! apocrine gland xref: BTO:0002324 ! merocrine gland property_value: has_relational_adjective "merocrine" xsd:string [Term] id: UBERON:0012344 name: holocrine gland def: "A gland whose discharged secretion contains entire secreting cells." [BTO:0002325, Wikipedia:Holocrine_glands, Wikipedia:Holocrine] is_a: UBERON:0002530 {source="BTO"} ! gland xref: BTO:0002325 ! holocrine gland [Term] id: UBERON:0000382 name: apocrine sweat gland def: "Apocrine sweat glands are sweat glands composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. In humans, apocrine sweat glands are found only in certain locations of the body: the axillae (armpits), the areola of the nipples, and the genitoanal region. The ducts of apocrine glands open into the canals of hair follicles. The stimulus for the secretion of apocrine sweat glands is adrenaline, which is a hormone carried in the blood[WP]." [Wikipedia:Apocrine_sweat_gland] comment: A note of confusion is the difference between apocrine secretion and apocrine sweat gland. Apocrine secretion refers to the apical loss of a cell's membrane to create cell blebs, thus creating a secretory product. Apocrine sweat gland refers to a structure, not a secretion process. Apocrine sweat glands actually use a merocrine type secretion, or that mediated by exocytosis of secretory granules. When "apocrine gland" is used without the word sweat, it is often referring to the gland which uses merocrine secretion, and not the secretion method. The important difference in apocrine sweat gland structure is its larger lumen, compared to the more narrow lumen of the eccrine sweat gland. synonym: "glandula sudorifera apocrina" EXACT LATIN [Wikipedia:Apocrine_sweat_gland] xref: BTO:0001458 xref: FMA:59155 ! Apocrine sweat gland xref: ncithesaurus:Apocrine_Sweat_Gland ! Apocrine Sweat Gland xref: MESH:A10.336.899.206 ! apocrine gland is_a: UBERON:0001820 {source="FMA"} ! sweat gland is_a: UBERON:0010243 {source="Wikipedia", notes="The term apocrine sweat gland is a misnomer. While it was once thought that apocrine sweat glands were true apocrine glands\, it is now known that they use merocrine excretion. However\, they have retained the original name"} ! merocrine gland relationship: part_of UBERON:0001003 {source="FMA"} ! epidermis relationship: never_in_taxon NCBITaxon:9822 {source="http://www.nal.usda.gov/awic/pubs/swine/swine.htm"} ! Sus disjoint_from: UBERON:0000423 ! eccrine sweat gland xref: SCTID:399916008 ! Entire apocrine sweat gland subset: organ_slim xref: UMLS:C0930083 [Term] id: UBERON:0000423 name: eccrine sweat gland def: "An ordinary, or simple, sweat gland; they are of the merocrine type, unbranched, coiled, tubular glands that are distributed over almost all of the body surface, and promote cooling by evaporation of their secretion." [BTO:0002323, Wikipedia:Eccrine_sweat_gland] synonym: "eccrine gland" RELATED [FMA:59154] synonym: "merocrine sweat gland" RELATED [] synonym: "glandula sudorifera merocrina" EXACT LATIN [Wikipedia:Eccrine_sweat_gland] synonym: "glandula sudorifera eccrina" EXACT LATIN [Wikipedia:Eccrine_sweat_gland] xref: BTO:0002323 ! eccrine sweat gland xref: FMA:59154 ! Eccrine sweat gland xref: ncithesaurus:Eccrine_Sweat_Gland ! Eccrine Sweat Gland xref: GAID:945 ! eccrine gland xref: MESH:A10.336.899.480 ! eccrine gland xref: SCTID:361699008 ! Entire eccrine gland is_a: UBERON:0001820 ! sweat gland is_a: UBERON:0010243 {source="BTO"} ! merocrine gland relationship: part_of UBERON:0001003 {source="FMA"} ! epidermis subset: organ_slim xref: UMLS:C0013492 [Term] id: UBERON:0000426 name: extravillous trophoblast synonym: "intermediate trophoblast" EXACT [FMA:86561] synonym: "interstitial trophoblast" RELATED [BTO:0002366] xref: BTO:0002366 xref: FMA:86561 ! Intermediate trophoblast is_a: UBERON:0002050 ! embryonic structure [Term] id: UBERON:0000427 name: obsolete cytotrophoblastic cell consider: ncithesaurus:Cytotrophoblastic_Cell ! Cytotrophoblastic Cell is_obsolete: true [Term] id: UBERON:0000430 name: ventral intermediate nucleus of thalamus def: "A nucleus medially located within the ventral nuclei of the thalamus." [BTO:0002469] subset: vertebrate_core synonym: "nucleus ventralis intermedius thalami" RELATED [BTO:0002469] xref: BTO:0002469 ! ventral intermediate nucleus of thalamus xref: FMA:84347 ! Ventral intermediate nucleus of thalamus xref: ZFA:0000370 ! intermediate thalamic nucleus xref: EV:0100208 ! ventral intermediate thalamic nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001900 {source="ZFA", source="BTO-definition"} ! subthalamus xref: TAO:0000370 ! intermediate thalamic nucleus synonym: "intermediate thalamic nucleus" RELATED [TAO:0000370] [Term] id: UBERON:0000431 name: ventral medial complex of thalamus synonym: "ventral medial nuclei of thalamus" EXACT [FMA:77795] synonym: "ventral medial complex of thalamus" EXACT [FMA:77795] synonym: "nuclei ventrales mediales thalami" RELATED [BTO:0002470] xref: BTO:0002470 xref: FMA:77795 ! Set of ventral medial nuclei of thalamus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001897 ! thalamus synonym: "set of ventral medial nuclei of thalamus" RELATED [FMA:77795] [Term] id: UBERON:0009641 ! ansa lenticularis name: ansa lenticularis def: "The ansa lenticularis (ansa lentiformis in older texts) is a part of the brain, making up the superior layer of the substantia innominata of Meynert. Its fibers, derived from the medullary lamina of the lentiform nucleus, pass medially to end in the thalamus and subthalamic region, while others are said to end in the tegmentum and red nucleus. It is classified by NeuroNames as part of the subthalamus." [Wikipedia:Ansa_lenticularis] synonym: "ansa lenticularis in thalamo" EXACT LATIN [FMA:TA] synonym: "ansa lenticularis in thalamus" EXACT [FMA:62070] synonym: "ventral peduncle of lateral forebrain bundle" EXACT [FMA:62070] is_a: UBERON:0002791 {source="NIF_GrossAnatomy"} ! regional part of telencephalon relationship: part_of UBERON:0001900 {source="FMA"} ! subthalamus xref: FMA:62070 ! ansa lenticularis xref: NIF_GrossAnatomy:nlx_anat_1010011 ! Ansa lenticularis xref: http://upload.wikimedia.org/wikipedia/commons/9/94/DA-loops_in_PD.jpg xref: SCTID:37467007 ! Entire ansa lenticularis [Term] id: UBERON:0009643 name: central tegmental tract def: "The central tegmental tract is a structure in the midbrain and pons. The central tegmental tract includes ascending axonal fibers which arise from the rostral nucleus solitarius and terminate in the ventral posteromedial nucleus (VPM) of thalamus. Information from the thalamus will go to cortical taste area, namely the insula and frontal operculum. It also contains descending axonal fibers from the parvocellular red nucleus. The descending axons will project to the inferior olivary nucleus. This latter pathway will be used to connect the contralateral cerebellum." [Wikipedia:Central_tegmental_tract] is_a: UBERON:0007702 {source="FMA"} ! tract of brain xref: FMA:83850 ! central tegmental tract xref: NIF_GrossAnatomy:nlx_anat_1010012 ! Central tegmental tract xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Midbrainsuperiorcolliculus.png xref: SCTID:369034000 ! Entire central tegmental tract [Term] id: UBERON:0000433 name: posterior paraventricular nucleus of thalamus synonym: "dorsal paraventricular nucleus of thalamus" EXACT [FMA:76961] synonym: "nucleus paraventricularis posterior thalami" RELATED [BTO:0002477] xref: BTO:0002477 xref: FMA:76961 ! Dorsal paraventricular nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0000434 name: anterior paraventricular nucleus of thalamus synonym: "ventral paraventricular nucleus of thalamus" EXACT [FMA:76962] synonym: "nucleus paraventricularis anterior thalami" RELATED [BTO:0002478] xref: BTO:0002478 xref: FMA:76962 ! Ventral paraventricular nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0006569 name: diencephalic nucleus xref: ZFA:0001659 ! diencephalic nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001894 ! diencephalon xref: TAO:0002191 ! diencephalic nucleus def: "A nucleus of brain that is part of a diencephalon." [OBOL:automatic] [Term] id: UBERON:0006568 name: hypothalamic nucleus synonym: "nucleus of hypothalamus" EXACT [FMA:258762] xref: BTO:0002449 ! hypothalamic nucleus xref: FMA:258762 ! nucleus of hypothalamus xref: MA:0002426 ! hypothalamic nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001898 ! hypothalamus xref: SCTID:279304003 ! Hypothalamic nucleus def: "A nucleus of brain that is part of a hypothalamus." [OBOL:automatic] [Term] id: UBERON:0000435 name: lateral tuberal nucleus def: "Nerve cell nuclei situated ventrally in the intermediate hypothalamic region, mainly in the lateral hypothalamic area." [BTO:0002481] synonym: "Lateral tuberal hypothalamic nuclei" EXACT [FMA:62336] synonym: "Lateral tuberal nuclei" EXACT [FMA:62336] synonym: "lateral tuberal nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_1206] synonym: "nuclei tuberales laterales" RELATED [BTO:0002481] xref: BTO:0002481 xref: FMA:62336 ! Lateral tuberal nucleus xref: NIF_GrossAnatomy:birnlex_1206 ! Lateral tuberal nuclear complex xref: EV:0100240 ! lateral tuberal nucleus xref: BM:TU ! lateral tuberal nucleus xref: ABA:TU ! Tuberal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002430 ! lateral hypothalamic area [Term] id: UBERON:0000438 name: obsolete set of arachnoid trabecula synonym: "Arachnoid trabeculae set" EXACT [FMA:77761] consider: FMA:77761 ! Set of arachnoid trabeculae is_obsolete: true synonym: "trabeculae arachnoideae" EXACT LATIN [FMA:TA, FMA:77761] [Term] id: UBERON:0000439 name: arachnoid trabecula def: "a small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue." [GO:0060343] synonym: "trabecula arachnoideum" RELATED LATIN [] xref: BTO:0002500 ! xref: FMA:83979 ! Arachnoid trabecula is_a: UBERON:0000440 ! trabecula relationship: has_part GO:0005581 ! collagen relationship: part_of UBERON:0002362 ! arachnoid mater [Term] id: UBERON:0000440 name: trabecula def: "A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like.. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]." [Wikipedia:Trabecula, GO:0060343] subset: grouping_class xref: BTO:0002501 ! trabecula xref: FMA:85273 ! Trabecula is_a: UBERON:0000064 ! organ part relationship: has_part GO:0005581 ! collagen property_value: has_relational_adjective "trabecular" xsd:string [Term] id: UBERON:0010183 name: liver trabecula def: "A trabecula that is part of a liver" [OBOL:automatic, GO:0060344] synonym: "hepatic trabecula" RELATED [] intersection_of: UBERON:0000440 ! trabecula intersection_of: part_of UBERON:0002107 ! liver [Term] id: UBERON:0005945 name: neurocranial trabecula synonym: "neurocranial trabeculae" EXACT PLURAL [ZFA:0001321] synonym: "trabecula" BROAD SENSU [ZFA:0001321] synonym: "trabecular cartilage" BROAD [ZFA:0001321] xref: ZFA:0001321 ! neurocranial trabecula xref: EFO:0003677 ! neurocranial trabecula is_a: UBERON:0000440 ! trabecula is_a: UBERON:0003932 {source="ZFA"} ! cartilage element of chondrocranium relationship: part_of UBERON:0003112 {source="ZFA"} ! olfactory region relationship: part_of UBERON:0001703 {source="ZFA"} ! neurocranium xref: TAO:0001321 ! neurocranial trabecula [Term] id: UBERON:0007215 ! trabecula cranii name: trabecula cranii def: "Paired thin medially aligned bar of cartilage that extends from the anterior end of the chondrocranium to just anterior to the anterior end of the notochord. The posterior ends of the trabeculae cranii are continuous with the parachordal cartilages, and they enclose the hypophyseal fenestra." [ZFIN:curator] comment: A paired cartilage element appearing in the preotic section of the head at the border between the brain and visceral structures (The Trabecula cranii: development and homology of an enigmatic vertebrate head structure - Cerny et al 2006) synonym: "trabeculae cranii" EXACT PLURAL [ZFA:0001507] xref: TAO:0001507 ! trabecula cranii xref: ZFA:0001507 ! trabecula cranii is_a: UBERON:0003932 ! cartilaginous elemenet of chondrocranium relationship: part_of UBERON:0005945 ! neurocranial trabecula [Term] id: UBERON:0000449 name: decidual cell def: "Before the fertilized ovum reaches the uterus, the mucous membrane of the body of the uterus undergoes important changes and is then known as the decidua. The thickness and vascularity of the mucous membrane are greatly increased; its glands are elongated and open on its free surface by funnel-shaped orifices, while their deeper portions are tortuous and dilated into irregular spaces. The interglandular tissue is also increased in quantity, and is crowded with large round, oval, or polygonal cells, termed decidual cells. Their enlargement is due to glycogen and lipid accumulation in the cytoplasm allowing these cells to provide a rich source of nutrition for the developing embryo. [WP,unvetted]." [Wikipedia:Decidual_cells] comment: request from CL xref: BTO:0002770 xref: FMA:86480 ! Decidual cell xref: ncithesaurus:Decidual_Cell ! Decidual Cell is_a: UBERON:0000478 ! extraembryonic structure xref: UMLS:C1511740 [Term] id: UBERON:0000450 name: corpus albicans def: "White fibrous tissue that replaces the regressing corpus luteum in the human ovary in the latter half of pregnancy, or soon after ovulation when pregnancy does not supervene." [BTO:0002784] synonym: "corpus albicans of ovary" EXACT [FMA:18620] synonym: "corpus fibrosum" RELATED [BTO:0002784] synonym: "corpus mamillare" RELATED [BTO:0002784] synonym: "mamillary body" RELATED INCONSISTENT [BTO:0002784] synonym: "mammillary body" RELATED INCONSISTENT [BTO:0002784] xref: BTO:0002784 xref: FMA:18620 ! Corpus albicans xref: EMAPA:29888 ! corpus albicans is_a: UBERON:0003982 {source="BTO"} ! mature ovarian follicle xref: SCTID:258043001 ! Entire corpus albicans of ovary [Term] id: UBERON:0001384 name: primary motor cortex def: "a brain region that in humans is located in the posterior portion of the frontal lobe. It works in association with pre-motor areas to plan and execute movements. M1 contains large neurons known as Betz cells which send long axons down the spinal cord to synapse onto alpha motor neurons which connect to the muscles. Pre-motor areas are involved in planning actions (in concert with the basal ganglia) and refining movements based upon sensory input (this requires the cerebellum). The human primary motor cortex is located in the dorsal part of the precentral gyrus and the anterior bank of the central sulcus. The precentral gyrus is in front of the postcentral gyrus from which it is separated by the central sulcus. Its anterior border is the precentral sulcus, while inferiorly it borders to the lateral fissure (Sylvian fissure). Medially, it is contiguous with the paracentral lobule." [Wikipedia:Primary_motor_cortex] comment: TODO: in MA this is asserted to be part_of BOTH frontal and parietal cortex. in ABA these are disjoint. FMA makes no commitment beyond cerebral cortex. Wikipedia says frontal lobe. Check if species difference or difference in definition. Removed relationship: part_of UBERON:0001872 {source="MA-modified"} ! parietal lobe subset: uberon_slim synonym: "motor cortex" EXACT [FMA:224854] synonym: "prefrontal gyrus" RELATED [MP:0000798, Wikipedia:Primary_motor_cortex] xref: FMA:224854 ! Primary motor cortex xref: MA:0000907 ! primary motor cortex xref: EFO:0002472 ! somatomotor cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/eb/Ba4.png/200px-Ba4.png xref: BTO:0004348 ! motor cortex xref: MESH:A08.186.211.730.885.213.270.548 ! motor cortex xref: BM:Tel-Cx-M1 ! primary motor cortex is_a: UBERON:0002619 ! region of cerebral cortex relationship: part_of UBERON:0001870 {source="MA", source="Wikipedia"} ! frontal cortex relationship: part_of UBERON:0001950 ! neocortex xref: SCTID:11931008 ! Motor cortex xref: ncithesaurus:Primary_Motor_Cortex ! primary motor cortex synonym: "gyrus precentralis" RELATED LATIN [Wikipedia:Primary_motor_cortex] xref: http://upload.wikimedia.org/wikipedia/commons/e/eb/Ba4.png property_value: external_definition "the area of the frontal lobe that is involved with integration of voluntary movements and with speech.[MP]" xsd:string {ontology="MP", external_class="MP:0000800", date_retrieved="2012-08-31", source="MGI:csmith"} xref: UMLS:C0026607 [Term] id: UBERON:0000451 name: prefrontal cortex def: "The prefrontal cortex (PFC) is the anterior part of the frontal lobes of the brain, lying in front of the motor and premotor areas. This brain region has been implicated in planning complex cognitive behaviors, personality expression, decision making and moderating correct social behavior. The basic activity of this brain region is considered to be orchestration of thoughts and actions in accordance with internal goals. The most typical psychological term for functions carried out by the pre-frontal cortex area is executive function. Executive function relates to abilities to differentiate among conflicting thoughts, determine good and bad, better and best, same and different, future consequences of current activities, working toward a defined goal, prediction of outcomes, expectation based on actions, and social 'control' (the ability to suppress urges that, if not suppressed, could lead to socially-unacceptable outcomes). Many authors have indicated an integral link between a person's personality and the functions of the prefrontal cortex. [WP,unvetted]." [Wikipedia:Prefrontal_cortex, Wikipedia:Prefrontal_cortex] comment: TODO - check MA synonym: "prefrontal association cortex" EXACT [FMA:224850] synonym: "frontal association cortex" RELATED ATTRIBUTION_REQUIRED [MA:0000906] synonym: "prefrontal association complex" RELATED [BTO:0002807] xref: BTO:0002807 xref: FMA:224850 ! Prefrontal cortex xref: EFO:0001384 ! prefrontal cortex xref: GAID:676 ! prefrontal cortex xref: MA:0000906 ! frontal association cortex xref: NIF_GrossAnatomy:nlx_anat_090801 ! Prefrontal cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/59/Gray726-Brodman-prefrontal.svg/200px-Gray726-Brodman-prefrontal.svg.png xref: MESH:A08.186.211.730.885.213.270.700 ! prefrontal cortex is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0001870 ! frontal cortex xref: http://upload.wikimedia.org/wikipedia/commons/5/59/Gray726-Brodman-prefrontal.svg [Term] id: UBERON:0000454 name: cerebral subcortex synonym: "Cerebral medulla" EXACT [FMA:242188] synonym: "subcortex" RELATED [BTO:0002858] xref: BTO:0002858 xref: FMA:242188 ! Cerebral subcortex is_a: UBERON:0000064 ! organ part xref: ncithesaurus:Cerebral_Subcortex ! cerebral subcortex [Term] id: UBERON:0000456 alt_id: UBERON:0006540 name: bodily secretion def: "Body substance in a liquid or semisolid state produced by an exocrine gland. Example: saliva, sebum, blood, plasma, semen, urine." [FMA:9675] comment: AO notes: BTO has two distunct classes, with exocrine glandular secretion a subtype of secretion - however, all examples in BTO directly under secretion appear to be exocrine gland secretions synonym: "external secretion" RELATED [BTO:0002977] synonym: "exocrine gland fluid" RELATED [] synonym: "exocrine gland secretion" RELATED [] synonym: "exocrine gland fluid or secretion" RELATED [] synonym: "secretion" RELATED [FMA:9675] synonym: "secreted substance" EXACT [] synonym: "exocrine gland fluid/secretion" EXACT [MA:0002504] xref: BTO:0002979 xref: FMA:9675 ! Secretion xref: galen:Secretion ! secretion xref: MESH:A12.200 ! bodily secretion xref: MA:0002504 ! exocrine gland fluid/secretion xref: BTO:0002977 ! exocrine glandular secretion xref: ncithesaurus:Exocrine_Gland_Fluid_or_Secretion ! Exocrine Gland Fluid or Secretion xref: AEO:0001005 ! secretion intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0002365 ! exocrine gland xref: UMLS:C1516992 [Term] id: UBERON:0000457 name: cavernous artery synonym: "Cavernous branch of cavernous part of internal carotid artery" EXACT [FMA:70527] xref: BTO:0002996 xref: FMA:70527 ! Cavernous artery is_a: UBERON:0000063 ! organ segment is_a: UBERON:0001637 ! artery synonym: "ramus sinus cavernosi (pars cavernosa) (arteria carotis interna)" EXACT LATIN [FMA:TA, FMA:70527] [Term] id: UBERON:0000459 name: uterine wall def: "An anatomical wall that is part of a uterus [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of uterus" EXACT [OBOL:automatic] synonym: "uterus anatomical wall" EXACT [OBOL:automatic] synonym: "uterus wall" EXACT [OBOL:automatic] synonym: "wall of uterus" EXACT [OBOL:automatic] xref: BTO:0003083 xref: FMA:17560 ! Wall of uterus is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus xref: SCTID:245485002 ! Uterine wall [Term] id: UBERON:0011826 ! vestibular gland name: vestibular gland def: "Lobular organ the parenchyma of which consists of glandular acini which communicate with the vestibule of vagina. Examples: right vestibular gland, lesser vestibular gland." [FMA:20020, Wikipedia:Vestibular_glands] subset: grouping_class is_a: UBERON:0005398 ! female reproductive gland relationship: part_of UBERON:0000474 ! female reproductive system xref: FMA:20020 ! vestibular gland [Term] id: UBERON:0000460 ! major vestibular gland name: major vestibular gland def: "Gland found in pairs located slightly below and to the left and right of the opening of the vagina in women. Bartholin's glands are homologous to bulbourethral glands in males. However, while Bartholin's glands are located in the superficial perineal pouch, bulbourethral glands are located in the deep perineal pouch. They secrete mucus to provide vaginal lubrication." [Wikipedia:Bartholin's_gland] synonym: "Bartholin's gland" EXACT [FMA:9598] synonym: "Duverney's gland" RELATED [FMA:9598] synonym: "Tiedemann's gland" EXACT [FMA:9598] synonym: "vulvovaginal gland" EXACT [FMA:9598] synonym: "greater vestibular gland" RELATED [MA:0002936] synonym: "glandula vestibularis major" RELATED [BTO:0003115] synonym: "greater vestibular glands of bartholin" RELATED [Wikipedia:Bartholin%27s_gland] xref: BTO:0003115 xref: FMA:9598 ! Greater vestibular gland xref: GAID:384 ! bartholin's gland xref: MA:0002936 ! bartholin's gland xref: MESH:A05.360.319.887.220 ! bartholin's gland is_a: UBERON:0011826 ! vestibular gland relationship: part_of UBERON:0002330 ! exocrine system relationship: part_of UBERON:0002416 {source="FMA"} ! integumental system relationship: sexually_homologous_to UBERON:0002366 {source="Wikipedia"} ! bulbo-urethral gland relationship: secretes UBERON:0000912 ! mucus relationship: develops_from UBERON:0000164 {source="Wikipedia"} ! primitive urogenital sinus xref: SCTID:362244005 ! Entire Bartholin's gland subset: organ_slim relationship: in_lateral_side_of UBERON:0005056 {source="FMA-abduced-lr"} ! external female genitalia [Term] id: UBERON:0010150 name: duct of major vestibular gland def: "One of a pair of ducts leading from the Bartholin's glands to the surface of the vulva" [Wikipedia:Bartholin's_duct] synonym: "greater vestibular gland duct" EXACT [FMA:20088] synonym: "Bartholin's duct" RELATED INCONSISTENT [Wikipedia:Bartholin's_duct] synonym: "duct of greater vestibular gland" EXACT [FMA:20088] intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0000460 ! major vestibular gland relationship: homologous_to UBERON:0010151 ! duct of bulbourethral gland xref: FMA:20088 ! duct of greater vestibular gland disjoint_from: UBERON:0003985 ! major sublingual duct [Term] id: UBERON:0000461 name: minor vestibular gland def: "Small mucous glands opening upon the vestibular mucous membrane between the urethral and the vaginal orifice." [BTO:0003116] comment: Editors note: compare with Skene's gland. Structure notes: check and part_of relationships to mammalian vulva / urethra synonym: "glandula vestibular minor" EXACT [FMA:20019] synonym: "lesser vestibular gland" EXACT [FMA:20019] synonym: "glandula vestibulares minor" RELATED [BTO:0003116] synonym: "Guerin's gland" RELATED [BTO:0003116] synonym: "Guérin's gland" RELATED [] synonym: "paraurethral gland" RELATED [BTO:0003116] synonym: "periurethral gland" RELATED [BTO:0003116] synonym: "Schueller's gland" RELATED [BTO:0003116] synonym: "skene's gland" RELATED [BTO:0003116] synonym: "urethral gland of female urethra" RELATED [BTO:0003116] synonym: "female urethral gland" BROAD [EMAPA:29653] xref: BTO:0003116 xref: FMA:20019 ! Lesser vestibular gland is_a: UBERON:0010145 {source="ncithesaurus"} ! paraurethral gland is_a: UBERON:0011826 ! vestibular gland relationship: part_of UBERON:0000474 {source="FMA"} ! female reproductive system relationship: part_of UBERON:0001334 ! female urethra xref: SCTID:279869001 ! Entire minor vestibular gland xref: ncithesaurus:Skene_s_Gland ! skene gland subset: organ_slim [Term] id: UBERON:0010145 ! paraurethral gland name: paraurethral gland def: "In human anatomy (female), the Skene's glands (also known as the lesser vestibular glands, periurethral glands, skene glands, paraurethral glands, U-spot, or female prostate) are glands located on the anterior wall of the vagina, around the lower end of the urethra. They drain into the urethra and near the urethral opening. These glands are surrounded with tissue, which includes the part of the clitoris that reaches up inside the vagina and swells with blood during sexual arousal." [Wikipedia:Skene%27s_gland] comment: AO notes: in MP female urethral gland, Skene gland and paraurethral gland are exact syns. Note that NCITA seems to use the term in a more generic way, as a parent for skene gland, cowper gland (which may be the same as the male bulbo-urethral gland) synonym: "female urethral gland" RELATED INCONSISTENT [] synonym: "U-spot" RELATED [Wikipedia:Skene%27s_gland] synonym: "periurethral gland" EXACT [Wikipedia:Skene%27s_gland] synonym: "female prostate" EXACT [PMID:10668204, Wikipedia:Skene%27s_gland] synonym: "para-urethral gland" EXACT [FMA:20083] synonym: "Skene's gland" EXACT [FMA:20083] synonym: "Skene gland" EXACT [] is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0000474 {source="FMA"} ! female reproductive system relationship: sexually_homologous_to UBERON:0002367 {source="PMID:10668204"} ! prostate gland xref: FMA:20083 ! paraurethral gland xref: SCTID:264125007 ! Entire paraurethral gland xref: ncithesaurus:Paraurethral_Gland ! Paraurethral Gland synonym: "glandulae vestibulares minores" RELATED LATIN [Wikipedia:Skene%27s_gland] xref: http://upload.wikimedia.org/wikipedia/commons/b/b8/Skenes_gland.jpg xref: UMLS:C0221315 [Term] id: UBERON:0001338 name: urethral gland def: "any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine" [MP:anna] subset: uberon_slim synonym: "urethra gland (male or female)" EXACT [] synonym: "urethra gland" EXACT [] synonym: "gland of urethra" EXACT [OBOL:automatic] xref: FMA:19683 ! Urethral gland xref: MA:0001688 ! urethra gland is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0002330 ! exocrine system relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: SCTID:279477005 ! Entire urethral gland subset: organ_slim [Term] id: UBERON:0010186 name: male urethral gland def: "Any of the many glands that branch off the wall of the urethra of male mammals. The glands secrete mucus, which is incorporated into the semen, and are most numerous in the section of the urethra that runs through the penis. [WP,unvetted]." [Wikipedia:Urethral_gland] synonym: "Littre's gland" EXACT [FMA:21443] synonym: "gland of male urethra" EXACT [] synonym: "gland of Littre" EXACT [] synonym: "male urethra gland" EXACT [] intersection_of: UBERON:0001338 ! urethral gland intersection_of: part_of UBERON:0001333 ! male urethra xref: FMA:21443 ! urethral gland (male) xref: SCTID:303562001 ! Entire Littre's gland xref: EMAPA:29645 ! male urethral gland synonym: "glandulae urethrales urethrae masculinae" RELATED LATIN [Wikipedia:Urethral_gland] xref: ncithesaurus:Urethral_Gland ! gland of littre synonym: "urethral gland (male)" EXACT [FMA:21443] xref: UMLS:C1314737 [Term] id: UBERON:0010187 name: female urethral gland def: "An urethral gland that is part of a female urethra." [OBOL:automatic] synonym: "urethral gland (female)" EXACT [FMA:21444] synonym: "gland of female urethra" EXACT [] synonym: "female urethra gland" EXACT [] intersection_of: UBERON:0001338 ! urethral gland intersection_of: part_of UBERON:0001334 ! female urethra xref: FMA:21444 ! urethral gland (female) xref: SCTID:279476001 ! Female urethral gland xref: EMAPA:29653 ! female urethral gland [Term] id: UBERON:0010146 name: paraurethral duct def: "The Skene's ducts are a pair of ducts leading from the Skene's glands to the surface of the vulva, to the left and right of the urethral opening. Like the Skene's glands, they are named after Alexander Skene." [Wikipedia:Skene%27s_ducts] comment: AO notes: FMA has separate class 'duct of paraurethral gland' (FMA:21860) synonym: "duct of Skene's gland" EXACT INCONSISTENT [FMA:21860] synonym: "paraurethral gland duct" EXACT INCONSISTENT [FMA:21860] synonym: "duct of paraurethral gland" EXACT INCONSISTENT [FMA:21860] synonym: "Skene's duct" EXACT [FMA:21445] synonym: "periurethral duct" EXACT [] synonym: "female prostate duct" EXACT [PMID:10668204] synonym: "ductus paraurethrales urethrae femininae" RELATED LATIN [Wikipedia:Skene%27s_ducts] intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0010145 ! paraurethral gland relationship: homologous_to UBERON:0002485 {source="PMID:10668204"} ! prostate duct xref: FMA:21445 ! paraurethral duct xref: SCTID:279480006 ! Entire paraurethral ducts xref: http://upload.wikimedia.org/wikipedia/commons/b/b8/Skenes_gland.jpg [Term] id: UBERON:0000462 name: obsolete villus is_obsolete: true [Term] id: UBERON:0000463 name: portion of organism substance def: "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [CARO:MAH] subset: upper_level synonym: "body fluid or substance" EXACT [MA:0002450] synonym: "portion of body substance" EXACT [FMA:9669] synonym: "body substance" EXACT [FMA:9669] synonym: "organism substance" EXACT [] xref: BILA:0000004 xref: CARO:0000004 ! portion of organism substance xref: FBbt:00007019 ! portion of organism substance xref: HAO:0000004 ! portion of organism substance xref: ZFA:0001487 ! portion of organism substance xref: FMA:9669 ! Portion of body substance xref: EHDAA2:0003004 ! portion of organism substance xref: AEO:0000004 ! portion of organism substance xref: MA:0002450 ! body fluid or substance xref: TGMA:0001824 ! portion of organism substance is_a: UBERON:0000465 ! material anatomical entity relationship: part_of UBERON:0000468 ! multi-cellular organism xref: ncithesaurus:Body_Fluid_or_Substance ! Body Fluid or Substance xref: galen:BodySubstance xref: AAO:0010839 ! portion of organism substance xref: XAO:0004001 ! portion of organism substance xref: SPD:0000008 ! portion of organism substance xref: TAO:0001487 ! portion of organism substance xref: VHOG:0001726 ! portion of organism substance [Term] id: UBERON:0006314 ! bodily fluid name: bodily fluid def: "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." [MESH:A12.207, Wikipedia:Body_fluid] comment: consider merging with parent class synonym: "body fluid" EXACT [GAID:266] xref: NIF_GrossAnatomy:birnlex_20 ! Bodily fluid xref: GAID:266 ! body fluid xref: MESH:A12.207 ! body fluid is_a: UBERON:0000463 ! portion of organism substance relationship: output_of GO:0007589 ! body fluid secretion xref: galen:BodyFluid [Term] id: UBERON:0007779 name: transudate def: "Body substance in liquid state, which is derived from plasma by passage through the (intact) wall of capillaries without further processing by secretory cells or glands." [FMA:12276] xref: FMA:12276 ! transudate xref: MESH:A12.383 ! (also: UBERON:0007780 'exudate') xref: GAID:1195 ! exudates and transudate is_a: UBERON:0006314 ! bodily fluid is_a: UBERON:0000463 {source="FMA"} ! portion of organism substance xref: ncithesaurus:Transudate ! Transudate property_value: has_relational_adjective "transudative" xsd:string [Term] id: UBERON:0007793 name: labyrinthine fluid def: "Fluids found within the osseous labyrinth (PERILYMPH) and the membranous labyrinth (ENDOLYMPH) of the inner ear. (From Gray's Anatomy, 30th American ed, p1328, 1332)" [MESH:A12.207.571] synonym: "labyrinthine fluid" RELATED [MESH:A12.207.571] xref: MESH:A12.207.571 ! labyrinthine fluid xref: GAID:1183 ! labyrinthine fluid is_a: UBERON:0006314 {source="MESH"} ! bodily fluid [Term] id: UBERON:0007794 name: serous fluid def: "Transudate contained in a serous sac." [FMA:20932] xref: FMA:20932 ! serous fluid is_a: UBERON:0007779 {source="FMA"} ! transudate [Term] id: UBERON:0000464 name: anatomical space def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [CARO:MAH] subset: upper_level synonym: "lumen" BROAD [] synonym: "lumen space" EXACT [] synonym: "space" BROAD [] xref: BILA:0000005 xref: CARO:0000005 ! anatomical space xref: FBbt:00007017 ! anatomical space xref: FMA:5897 ! Anatomical space xref: HAO:0000005 ! anatomical space xref: TAO:0001668 ! anatomical space xref: ZFA:0001643 ! anatomical space xref: EHDAA2:0003005 ! anatomical space xref: AEO:0000005 ! anatomical space xref: XAO:0003190 ! anatomical space xref: TGMA:0001825 ! anatomical space is_a: UBERON:0000466 ! immaterial anatomical entity relationship: surrounded_by UBERON:0000061 ! anatomical structure xref: AAO:0010110 ! anatomical space xref: VHOG:0001728 ! anatomical space xref: ncithesaurus:Lumen_Space ! lumen xref: UMLS:C0524461 [Term] id: UBERON:0000465 name: material anatomical entity def: "Anatomical entity that has mass." [CARO:MAH] subset: upper_level xref: BILA:0000006 xref: CARO:0000006 ! material anatomical entity xref: FBbt:00007016 ! material anatomical entity xref: FMA:67165 ! Material anatomical entity xref: HAO:0000006 ! material anatomical entity xref: TAO:0001836 ! material anatomical entity xref: EHDAA2:0003006 ! material anatomical entity xref: AEO:0000006 ! material anatomical entity xref: TGMA:0001826 ! material anatomical entity is_a: UBERON:0001062 ! anatomical entity xref: AAO:0010264 ! material anatomical entity xref: VHOG:0001721 ! material anatomical entity [Term] id: UBERON:0000466 name: immaterial anatomical entity def: "Anatomical entity that has no mass." [CARO:MAH] subset: disjointness_axiom_removed subset: upper_level synonym: "immaterial physical anatomical entity" EXACT [FMA:67112] xref: BILA:0000007 xref: CARO:0000007 ! immaterial anatomical entity xref: FBbt:00007015 ! immaterial anatomical entity xref: HAO:0000007 ! immaterial anatomical entity xref: FMA:67112 ! Immaterial anatomical entity xref: EHDAA2:0003007 ! immaterial anatomical entity xref: AEO:0000007 ! immaterial anatomical entity xref: TGMA:0001827 ! immaterial anatomical entity is_a: UBERON:0001062 ! anatomical entity xref: AAO:0010265 ! immaterial anatomical entity xref: TAO:0001835 ! immaterial anatomical entity xref: VHOG:0001727 ! immaterial anatomical entity [Term] id: UBERON:0000467 name: anatomical system def: "Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity[CARO]. A group of organs that work together to perform a certain task [Wikipedia]." [CARO:0000011, CARO:MAH, Wikipedia:Organ_system] subset: uberon_slim subset: upper_level synonym: "body system" EXACT [NIF_GrossAnatomy:birnlex_14] synonym: "organ system" EXACT [] synonym: "system" BROAD [GO:0048731] xref: AAO:0000007 ! anatomical_system xref: BILA:0000011 xref: CARO:0000011 ! anatomical system xref: EHDAA:392 ! organ system xref: EHDAA2:0003011 ! anatomical system xref: FBbt:00004856 ! organ system xref: FMA:7149 ! Organ system xref: galen:AnatomicalSystem xref: HAO:0000011 ! anatomical system xref: MA:0000003 ! organ system xref: TAO:0001439 ! anatomical system xref: XAO:0003002 ! anatomical system xref: ZFA:0001439 ! anatomical system xref: ncithesaurus:Organ_System ! Organ System xref: OpenCyc:Mx4rCWM0QCtDEdyAAADggVbxzQ ! organ system xref: EHDAA2:0001330 ! organ system xref: AEO:0000011 ! anatomical system xref: TGMA:0001831 ! anatomical system xref: EMAPA:16103 ! organ system xref: WBbt:0005746 ! Organ system xref: EV:0100000 ! Anatomical System xref: NIF_GrossAnatomy:birnlex_14 ! Body system xref: SCTID:278195005 ! Entire body system is_a: UBERON:0000480 ! anatomical group relationship: part_of UBERON:0000468 ! multi-cellular organism property_value: external_definition "Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000007", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity.[CARO]" xsd:string {ontology="CARO", external_class="CARO:0000011", date_retrieved="2012-06-20", source="CARO:MAH", source="FMA:7149"} xref: VHOG:0001725 ! anatomical system property_value: external_definition "Anatomical group that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001439", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0460002 [Term] id: UBERON:0000468 name: multi-cellular organism def: "Anatomical structure that is an individual member of a species and consists of more than one cell." [CARO:0000012, CARO:MAH, Wikipedia:Multi-cellular_organism] comment: TODO - split body and mc organism? body continues after death stage subset: uberon_slim subset: upper_level synonym: "organism" EXACT [] synonym: "whole organism" EXACT [] synonym: "body" EXACT [] synonym: "adult mouse" EXACT [MA:0002405] synonym: "TS28" RELATED [MA:0002405] synonym: "whole body" EXACT [BTO:0001489] synonym: "Koerper" RELATED [BTO:0001489] xref: BILA:0000012 xref: CARO:0000012 ! multi-cellular organism xref: HAO:0000012 ! multi-cellular organism xref: TAO:0001094 ! body xref: XAO:0003004 ! whole organism xref: ZFA:0001094 ! whole organism xref: FMA:256135 ! Body xref: MA:0002405 ! adult mouse (also: UBERON:0009953 'post-embryonic organism') xref: ncithesaurus:Whole_Organism ! Whole Organism xref: NIF_GrossAnatomy:birnlex_18 ! Body xref: EHDAA2:0003103 ! body xref: AEO:0000103 ! body xref: AEO:0000191 ! multi-cellular organism xref: BTO:0001489 ! whole body xref: TADS:0000001 ! adult body xref: TGMA:0001832 ! multi-cellular organism xref: VHOG:0000671 ! organism xref: FBbt:00000001 ! organism xref: WBbt:0007833 ! organism xref: EMAPA:25765 ! mouse xref: EHDAA:1 ! human xref: EHDAA2:0003191 ! multi-cellular organism xref: EHDAA:9178 ! body (also: UBERON:0001150 'body of pancreas') xref: EV:0100016 ! whole body xref: EFO:0002906 ! whole organism is_a: UBERON:0000061 ! anatomical structure xref: galen:Organism xref: AAO:0010026 ! multi-cellular organism xref: SCTID:243928005 ! Entire body region property_value: external_definition "Anatomical structure that is an individual member of a species.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001094", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "organismal" xsd:string [Term] id: UBERON:0000470 name: cell part def: "Anatomical structure that is a direct part of the cell." [CARO:MAH] comment: todo - move metadata to GO and obsolete this class. Note the inconsistency between the usage of the label 'cell component' in GO and CARO subset: upper_level synonym: "cell component" RELATED [CARO:0000014] xref: BILA:0000014 xref: CARO:0000014 ! cell component xref: FBbt:00007012 ! cell component xref: FMA:86454 ! Cell component xref: GO:0044464 xref: HAO:0000014 ! cell component xref: ncithesaurus:Cell_Part ! Cell Part xref: OpenCyc:Mx4rwQwkcZwpEbGdrcN5Y29ycA ! cell part xref: NIF_Subcellular:sao-1337158144 ! Cellular Component xref: TGMA:0001834 ! cell component is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: part_of CL:0000000 ! cell relationship: part_of CL:0000000 ! cell xref: AAO:0010271 ! cell component xref: UMLS:C1178969 [Term] id: UBERON:0000471 name: compound organ component def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019, CARO:MAH] subset: upper_level xref: BILA:0000019 xref: CARO:0000019 ! compound organ component xref: HAO:0000019 ! compound organ component xref: TAO:0001489 ! compound organ component xref: XAO:0003039 ! compound organ component xref: ZFA:0001489 ! compound organ component xref: EHDAA2:0003019 ! compound organ component xref: AEO:0000019 ! compound organ component xref: TGMA:0001835 ! compound organ component is_a: UBERON:0000481 ! multi-tissue structure xref: AAO:0010017 ! compound organ component [Term] id: UBERON:0000472 name: simple organ def: "Multi-tissue structure that is not part of a compound organ." [CARO:0000021, CARO:MAH] subset: upper_level xref: BILA:0000021 xref: CARO:0000021 ! simple organ xref: HAO:0000021 ! simple organ xref: TAO:0001492 ! simple organ xref: XAO:0003038 ! simple organ xref: ZFA:0001492 ! simple organ xref: EHDAA2:0003190 ! simple organ xref: AEO:0000190 ! simple organ xref: TGMA:0001836 ! simple organ is_a: UBERON:0000481 ! multi-tissue structure xref: AAO:0010051 ! simple organ [Term] id: UBERON:0000473 name: testis alt_id: UBERON:0002117 def: "gonad of a male animal, produces and releases sperm." [Wikipedia:Testis] subset: uberon_slim subset: vertebrate_core synonym: "testes" RELATED PLURAL [] synonym: "gonad of male genitalia" EXACT [OBOL:automatic] synonym: "gonad of male genitals" EXACT [OBOL:automatic] synonym: "gonad of male reproductive system" EXACT [OBOL:automatic] synonym: "gonada of male genitalia" EXACT [OBOL:automatic] synonym: "gonada of male genitals" EXACT [OBOL:automatic] synonym: "gonada of male reproductive system" EXACT [OBOL:automatic] synonym: "male genitalia gonad" EXACT [OBOL:automatic] synonym: "male genitalia gonada" EXACT [OBOL:automatic] synonym: "male genitals gonad" EXACT [OBOL:automatic] synonym: "male gonad" EXACT [OBOL:automatic] synonym: "male reproductive system gonad" EXACT [OBOL:automatic] synonym: "male reproductive system gonada" EXACT [OBOL:automatic] synonym: "genitalia of male organism gonad" EXACT [OBOL:automatic] synonym: "genitalia of male organism gonada" EXACT [OBOL:automatic] synonym: "gonad of genitalia of male organism" EXACT [OBOL:automatic] synonym: "gonad of male organism genitalia" EXACT [OBOL:automatic] synonym: "gonad of male organism reproductive system" EXACT [OBOL:automatic] synonym: "gonad of reproductive system of male organism" EXACT [OBOL:automatic] synonym: "gonada of genitalia of male organism" EXACT [OBOL:automatic] synonym: "gonada of male organism genitalia" EXACT [OBOL:automatic] synonym: "gonada of male organism reproductive system" EXACT [OBOL:automatic] synonym: "gonada of reproductive system of male organism" EXACT [OBOL:automatic] synonym: "male organism genitalia gonad" EXACT [OBOL:automatic] synonym: "male organism genitalia gonada" EXACT [OBOL:automatic] synonym: "male organism reproductive system gonad" EXACT [OBOL:automatic] synonym: "male organism reproductive system gonada" EXACT [OBOL:automatic] synonym: "reproductive system of male organism gonad" EXACT [OBOL:automatic] synonym: "reproductive system of male organism gonada" EXACT [OBOL:automatic] synonym: "testicle" EXACT [FMA:7210] synonym: "orchis" RELATED [BTO:0001363] synonym: "testiculus" RELATED [BTO:0001363] xref: AAO:0000606 ! testis xref: BILA:0000124 xref: BTO:0001363 xref: EHDAA:8146 ! testis xref: FBbt:00004928 ! testis xref: FMA:7210 ! Testis xref: GAID:396 ! testis xref: HAO:0001007 ! testis xref: VHOG:0000252 ! testis xref: MA:0000411 ! testis xref: MAT:0000132 ! testis xref: MIAA:0000132 ! testis xref: ncithesaurus:Testis xref: TAO:0000598 ! testis xref: WBbt:0006794 ! male gonad xref: XAO:0000157 ! testis xref: ZFA:0000598 ! testis xref: EFO:0000984 ! testis xref: OpenCyc:Mx4rvVjM25wpEbGdrcN5Y29ycA ! testicle xref: galen:Testis ! testis xref: EHDAA2:0002007 ! testis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Gray1144.png/200px-Gray1144.png xref: EMAPA:17972 ! testis xref: MESH:A05.360.444.849 ! testis xref: EV:0100102 ! testis is_a: UBERON:0000991 ! gonad intersection_of: UBERON:0000991 ! gonad intersection_of: part_of UBERON:0000079 ! male reproductive system relationship: part_of UBERON:0000079 ! male reproductive system relationship: develops_from UBERON:0009117 ! indifferent gonad relationship: in_lateral_side_of UBERON:0000468 {gci_relation="part_of", gci_filler="NCBITaxon:7742", notes="vertebrates"} ! multi-cellular organism xref: SCTID:181431007 ! Entire testis disjoint_from: UBERON:0000992 ! female gonad subset: organ_slim property_value: external_definition "Either of paired male reproductive organs which are involved in the production of sperm and male sex hormones.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000606", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Male reproductive organ.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000598", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {external_class="VHOG:0000252", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM\, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007)\, DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B\, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "testicular" xsd:string xref: UMLS:C0039597 [Term] id: UBERON:0009196 ! indifferent external genitalia name: indifferent external genitalia is_a: UBERON:0004176 {source="cjm"} ! external genitalia xref: EHDAA2:0004021 ! indifferent external genitalia disjoint_from: UBERON:0004053 ! external male genitalia disjoint_from: UBERON:0005056 ! external female genitalia subset: organ_slim [Term] id: UBERON:0009117 ! indifferent gonad name: indifferent gonad def: "A gonad prior to differentiating into a definitive testis or ovary." [http://www.medterms.com/script/main/art.asp?articlekey=8981] comment: typically part of the embryo - however, in male tammar wallabies the gonads are indifferent at the neonatal stage[8827321] is_a: UBERON:0000991 ! gonad relationship: part_of UBERON:0009196 ! indifferent external genitalia disjoint_from: UBERON:0000473 ! testis disjoint_from: UBERON:0000992 ! female gonad xref: EHDAA2:0000716 ! indifferent gonad xref: ncithesaurus:Indifferent_Gonad ! Indifferent Gonad subset: organ_slim xref: UMLS:C1512703 [Term] id: UBERON:0009118 name: marsupial pouch synonym: "pouch" BROAD [] def: "." [Wikipedia:Pouch_(marsupial)] is_a: UBERON:0005156 ! reproductive structure [Term] id: UBERON:0010896 name: piston cartilage is_a: UBERON:0002418 ! cartilage tissue comment: Composition notes: composed of lamprin, an elastin-like protein, unique to lampreys synonym: "lingual cartilage" EXACT [] synonym: "piston" RELATED [] synonym: "lamprey tongue" RELATED [] subset: cyclostome_subset [Term] id: UBERON:0011303 name: lamprey sucker is_a: UBERON:0000475 ! organism subdivision xref: http://purl.obolibrary.org/obo/uberon/images/lamprey_sucker_rosava_3238889218.jpg [Term] id: UBERON:0009120 ! gill filament name: gill filament def: "Portion of tissue that projects outward from the gill and is a thread-like, soft, red respiratory and excretory structure." [ZFIN:ZDB-PUB-961014-576, http:www.briancoad.com/Dictionary/G.htm] synonym: "gill filaments" EXACT PLURAL [ZFA:0000667] xref: TAO:0000667 ! gill filament is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0002535 {source="ZFA"} ! gill relationship: capable_of GO:0007585 ! respiratory gaseous exchange xref: ZFA:0000667 ! gill filament xref: BTO:0002150 ! gill filament property_value: external_definition "Branched region of the gill where respiratory exchange takes place. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000667", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: EFO:0003554 ! gill filament [Term] id: UBERON:0000474 name: female reproductive system def: "The organs of the female reproductive system." [Wikipedia:Female_genitalia] subset: uberon_slim synonym: "female genital system" RELATED [] synonym: "female genitalia" RELATED [] synonym: "female organism genitalia" EXACT [OBOL:automatic] synonym: "female organism reproductive system" EXACT [OBOL:automatic] synonym: "genitalia of female organism" EXACT [OBOL:automatic] synonym: "reproductive system of female organism" EXACT [OBOL:automatic] synonym: "female reproductive tract" RELATED [MA:0000381] synonym: "gynaecological tissue" RELATED [BTO:0000083] synonym: "systema genitale femininum" RELATED [BTO:0000083] xref: BTO:0000083 xref: FBbt:00004864 ! female reproductive system xref: FMA:45663 ! Female genital system xref: GAID:364 ! female genitalia xref: HAO:0000324 ! female genitalia xref: VHOG:0000726 ! female reproductive system xref: MA:0000381 ! female reproductive system xref: MIAA:0000028 ! reproductive system - female xref: ncithesaurus:Female_Reproductive_System xref: OpenCyc:Mx4rvVipTZwpEbGdrcN5Y29ycA xref: XAO:0000156 ! female genitalia xref: EFO:0000969 ! female reproductive system xref: OpenCyc:Mx4rvVipTZwpEbGdrcN5Y29ycA ! female reproductive system xref: EHDAA2:0000506 ! female reproductive system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/68/Scheme_female_reproductive_system-en.svg/200px-Scheme_female_reproductive_system-en.svg.png xref: TGMA:0000635 ! female genitalia xref: EMAPA:17959 ! female reproductive system (also: UBERON:0003134 'female reproductive organ') xref: WBbt:0006748 ! vulva xref: MESH:A05.360.319 ! female genitalia xref: EHDAA:8116 ! female xref: EV:0100110 ! female reproductive system xref: WikipediaCategory:Female_reproductive_system is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0003100 ! female organism xref: SCTID:361386004 ! Entire female genital system property_value: homology_notes "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000726", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J\, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0700038 [Term] id: UBERON:0003974 name: cranial vagina comment: Editor notes: relationship to caudal Mullerian duct? def: "the upper third of the vagina." [MP:0009077] synonym: "upper third of vagina" EXACT [] is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0000996 ! vagina xref: SCTID:362247003 ! Entire upper third of vagina [Term] id: UBERON:0000051 name: fornix of vagina def: "The deepest portions of the vagina, extending into the recesses created by the vaginal portion of cervix[WP,unvetted]." [Wikipedia:Vaginal_fornix] subset: uberon_slim synonym: "fornix" BROAD [] synonym: "vaginal fornix" EXACT [] synonym: "fornix vaginae" EXACT [] synonym: "vaginal fornices" RELATED PLURAL [] xref: FMA:19985 ! Fornix of vagina xref: ncithesaurus:Vaginal_Fornix ! Vaginal Fornix xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Female_anatomy.png/200px-Female_anatomy.png is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0000996 ! vagina disjoint_from: UBERON:0000052 ! fornix of brain synonym: "fornix vaginae" EXACT LATIN [FMA:TA, FMA:19985] xref: SCTID:245475003 ! Entire fornix of vagina xref: UMLS:C0227794 [Term] id: UBERON:0011894 name: lumen of vagina synonym: "vaginal lumen" EXACT [FMA:19982] synonym: "vaginal lumen" EXACT [] intersection_of: UBERON:0002558 ! organ cavity intersection_of: part_of UBERON:0000996 ! vagina xref: FMA:19982 ! lumen of vagina [Term] id: UBERON:0008330 name: vestibulum vaginae def: "The space posterior to the glans clitoridis and between the labia minora, containing the openings of the vagina, urethra, and ducts of the greater vestibular glands." [BTO:0003145, Wikipedia:Vulval_vestibule] synonym: "introitus of vagina" RELATED [MP:anna] synonym: "introitus" RELATED [] synonym: "vaginal introitus" RELATED [BTO:0003145] synonym: "vestibule of vagina" RELATED [BTO:0003145] synonym: "vestibulum pudendi" RELATED [BTO:0003145] synonym: "vagina vestibule" EXACT [MP:0011848] synonym: "vestibulum pudendi" EXACT [] synonym: "vaginal vestibule" EXACT [FMA:19970] synonym: "vestibule of vagina" EXACT [FMA:19970] synonym: "vaginal opening" RELATED [MP:0001142] synonym: "vagina opening" RELATED [MP:0001142] synonym: "vestibulum vaginae" RELATED LATIN [Wikipedia:Vulval_vestibule] is_a: UBERON:0001349 {source="FMA"} ! vestibule relationship: part_of UBERON:0005056 {source="FMA"} ! external female genitalia relationship: part_of UBERON:0000997 {source="BTO"} ! vulva xref: BTO:0003145 ! vestibulum vaginae xref: FMA:19970 ! vestibule of vagina xref: SCTID:181446000 ! Entire introitus of vagina xref: http://upload.wikimedia.org/wikipedia/commons/f/f3/Scheidenvorhof.jpg [Term] id: UBERON:0012317 name: vagina orifice def: "The vaginal orifice is a median slit below and behind the opening of the urethra; its size varies inversely with that of the hymen." [Wikipedia:Vaginal_orifice] synonym: "vaginal introitus" RELATED [] synonym: "introitus of vagina" RELATED INCONSISTENT [] synonym: "introitus" RELATED INCONSISTENT [FMA:19984] synonym: "ostium vaginae" EXACT [FMA:TA] synonym: "vaginal orifice" EXACT [FMA:19984] synonym: "orifice of vagina" EXACT [FMA:19984] synonym: "vaginal opening" EXACT [] intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0000996 ! vagina xref: FMA:19984 ! orifice of vagina [Term] id: UBERON:0001346 name: vaginal hymen def: "The hymen, or the vaginal corona, is a fold of mucous membrane that surrounds or partially covers the external vaginal opening. It forms part of the vulva, or external genitalia[WP]." [Wikipedia:Hymen] synonym: "hymen of vagina" EXACT [FMA:20005] synonym: "hymen vaginae" EXACT [] synonym: "hymen" BROAD [MESH:A05.360.319.779.479] synonym: "vaginal corona" RELATED [Wikipedia:Hymen] xref: FMA:20005 ! hymen of vagina xref: MA:0002465 ! vaginal hymen xref: MESH:A05.360.319.779.479 ! hymen xref: SCTID:245473005 ! Entire hymen xref: ncithesaurus:Hymen ! Hymen is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0000996 {source="FMA"} ! vagina synonym: "hymen vaginae" RELATED LATIN [Wikipedia:Hymen] xref: http://upload.wikimedia.org/wikipedia/commons/2/26/Gray1229.png xref: UMLS:C0020412 [Term] id: UBERON:0000475 name: organism subdivision def: "Anatomical structure which is a primary subdivision of whole organism. The mereological sum of these is the whole organism." [CARO:0000032, CARO:MAH, Wikipedia:Body_part] comment: Editor note: revise after CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency subset: uberon_slim subset: upper_level synonym: "body region" RELATED [FMA:7153] synonym: "body part" RELATED [] synonym: "cardinal body part" RELATED [FMA:7153] xref: BILA:0000032 xref: CARO:0000032 ! organism subdivision xref: FBbt:00007009 ! organism subdivision xref: FMA:7153 ! Cardinal body part xref: galen:BodyPart xref: HAO:0000032 ! organism subdivision xref: MAT:0000293 ! body part xref: MIAA:0000293 ! body part xref: TAO:0001308 ! organism subdivision xref: XAO:0003013 ! organism subdivision xref: ZFA:0001308 ! organism subdivision xref: ncithesaurus:Body_Part ! Body Part xref: EFO:0000808 ! animal body part xref: OpenCyc:Mx4rvViAHJwpEbGdrcN5Y29ycA ! body part xref: MA:0002433 ! anatomic region xref: EHDAA2:0003032 ! organism subdivision xref: AEO:0000032 ! organism subdivision xref: TGMA:0001840 ! organism subdivision xref: MESH:A01 ! body region is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000468 xref: AAO:0010053 ! organism subdivision xref: VHOG:0001758 ! organism subdivision synonym: "anatomic region" EXACT [MA:0002433] xref: UMLS:C0229962 [Term] id: UBERON:0000476 name: acellular anatomical structure def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [CARO:MAH] subset: vertebrate_core xref: BILA:0000040 xref: CARO:0000040 ! acellular anatomical structure xref: FBbt:00007013 ! acellular anatomical structure xref: FMA:63863 ! Acellular anatomical structure xref: HAO:0000040 ! acellular anatomical structure xref: TAO:0000382 ! acellular anatomical structure xref: XAO:0003162 ! acellular anatomical structure xref: ZFA:0000382 ! acellular anatomical structure xref: EHDAA2:0003040 ! acellular anatomical structure xref: AEO:0000040 ! acellular anatomical structure xref: TGMA:0001841 ! acellular anatomical structure is_a: UBERON:0000061 ! anatomical structure disjoint_from: UBERON:0000480 ! anatomical group xref: AAO:0010268 ! acellular anatomical structure property_value: external_definition "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or tissue.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010268", date_retrieved="2012-06-20", source="AAO:BJB"} [Term] id: UBERON:0000477 name: anatomical cluster def: "Anatomical group that has its parts adjacent to one another." [CARO:MAH] subset: disjointness_axiom_removed subset: upper_level xref: BILA:0000041 xref: CARO:0000041 ! anatomical cluster xref: FMA:49443 ! Anatomical cluster xref: HAO:0000041 ! anatomical cluster xref: TAO:0001478 ! anatomical cluster xref: XAO:0003160 ! anatomical cluster xref: ZFA:0001478 ! anatomical cluster xref: EHDAA2:0003041 ! anatomical cluster xref: AEO:0000041 ! anatomical cluster xref: TGMA:0001842 ! anatomical cluster xref: FBbt:00007277 ! anatomical cluster xref: TADS:0000605 ! anatomical cluster is_a: UBERON:0000480 ! anatomical group xref: AAO:0010009 ! anatomical cluster xref: VHOG:0001737 ! anatomical cluster [Term] id: UBERON:0000478 name: extraembryonic structure def: "Anatomical structure that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo." [CARO:MAH, https://cedar.bio.indiana.edu/trac/env/ontologies/ticket/279] comment: see also conceptus extraembryonic component in EHDAA2. Note that the FBbt class is *not* placed here until the tracker issue is resolved. subset: uberon_slim subset: vertebrate_core synonym: "extra-embryonic structure" EXACT [] synonym: "extraembryonic component" RELATED [] synonym: "extraembryonic tissue" RELATED [] xref: BILA:0000042 xref: CARO:0000042 ! extraembryonic structure xref: FMA:85537 ! Extra-embryonic structure xref: HAO:0000042 ! extraembryonic structure xref: VHOG:0000292 ! extraembryonic structure xref: TAO:0000020 ! extraembryonic structure xref: ZFA:0000020 ! extraembryonic structure xref: ncithesaurus:Extraembryonic_Structure ! Extraembryonic Structure xref: EHDAA2:0003042 ! extraembryonic structure xref: AEO:0000042 ! extraembryonic structure xref: TGMA:0001843 ! extraembryonic structure xref: EMAPA:16042 ! extraembryonic component xref: EHDAA:46 ! extraembryonic component intersection_of: UBERON:0000061 ! anatomical structure intersection_of: adjacent_to UBERON:0002050 ! embryonic structure intersection_of: existence_starts_and_ends_during UBERON:0000068 ! embryo stage disjoint_from: UBERON:0002050 ! embryonic structure property_value: seeAlso FBbt:00005835 xref: AAO:0010020 ! extraembryonic structure xref: SCTID:314908006 ! Extra-embryonic structure xref: XAO:0004005 ! extraembryonic structure xref: UMLS:C1282438 [Term] id: UBERON:0005292 name: extraembryonic tissue def: "Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo." [UBERON:cjm] synonym: "extra-embryonic tissue" EXACT [] xref: MAT:0000061 ! extraembryonic tissue xref: MIAA:0000061 ! extraembryonic tissue xref: BTO:0003360 ! extraembryonic tissue xref: EFO:0001406 ! extraembryonic tissue intersection_of: UBERON:0000479 ! portion of tissue intersection_of: adjacent_to UBERON:0002050 ! embryonic structure intersection_of: existence_starts_and_ends_during UBERON:0000068 ! embryo stage [Term] id: UBERON:0000479 name: tissue def: "Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships." [CARO:0000043, CARO:MAH, FMA:9637] comment: This class was sourced from CARO, which was initially sourced from FMA. Nomenclature changes have been made. Note also AEO introduces a class AEO:0000013 'single-cell tissue' subset: upper_level synonym: "portion of tissue" EXACT [CARO:0000043] synonym: "tissue portion" EXACT [] synonym: "simple tissue" EXACT [AEO:0000043] xref: BILA:0000043 xref: CARO:0000043 ! portion of tissue xref: FBbt:00007003 ! portion of tissue xref: FMA:9637 ! Portion of tissue xref: HAO:0000043 ! portion of tissue xref: TAO:0001477 ! portion of tissue xref: XAO:0003040 ! portion of tissue xref: ZFA:0001477 ! portion of tissue xref: AAO:0000607 ! tissue xref: NIF_GrossAnatomy:birnlex_19 ! Tissue xref: EHDAA2:0003043 ! simple tissue xref: TGMA:0001844 ! portion of tissue xref: WBbt:0005729 ! Tissue xref: MESH:A10 ! tissue xref: AEO:0000043 ! simple tissue is_a: UBERON:0000061 ! anatomical structure xref: ncithesaurus:Tissue ! Tissue xref: galen:Tissue xref: AAO:0010054 ! portion of tissue xref: MA:0003002 ! tissue xref: VHOG:0001757 ! portion of tissue xref: UMLS:C0040300 [Term] id: UBERON:0000480 name: anatomical group def: "Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue." [CARO:0000054, CARO:MAH] subset: upper_level xref: BILA:0000054 xref: CARO:0000054 ! anatomical group xref: HAO:0000054 ! anatomical group xref: TAO:0001512 ! anatomical group xref: XAO:0003001 ! anatomical group xref: ZFA:0001512 ! anatomical group xref: EHDAA2:0003054 ! anatomical group xref: AEO:0000054 ! anatomical group xref: TGMA:0001846 ! anatomical group is_a: UBERON:0000061 ! anatomical structure xref: AAO:0010008 ! anatomical group xref: VHOG:0001724 ! anatomical group [Term] id: UBERON:0000481 name: multi-tissue structure def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055, CARO:MAH] subset: upper_level xref: BILA:0000055 xref: CARO:0000055 ! multi-tissue structure xref: FBbt:00007010 ! multi-tissue structure xref: HAO:0000055 ! multi-tissue structure xref: TAO:0001488 ! multi-tissue structure xref: XAO:0003037 ! multi-tissue structure xref: ZFA:0001488 ! multi-tissue structure xref: EHDAA2:0003055 ! multi-tissue structure xref: AEO:0000055 ! multi-tissue structure xref: TGMA:0001847 ! multi-tissue structure is_a: UBERON:0000061 ! anatomical structure relationship: has_part UBERON:0000479 ! portion of tissue xref: AAO:0010048 ! multi-tissue structure xref: VHOG:0001762 ! multi-tissue structure [Term] id: UBERON:0000482 name: basal lamina def: "Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue." [CARO:MAH, Wikipedia:Basal_lamina] comment: TODO - use GO. subset: uberon_slim subset: vertebrate_core synonym: "basal lamina of connective tissue" EXACT [] xref: BILA:0000065 xref: CARO:0000065 ! basal lamina xref: FMA:62918 ! Basal lamina xref: HAO:0000065 ! basal lamina xref: TAO:0001485 ! basal lamina xref: WBbt:0005756 ! basal lamina xref: XAO:0003163 ! basal lamina xref: ZFA:0001485 ! basal lamina xref: ncithesaurus:Basal_Lamina ! Basal Lamina xref: GO:0005605 ! basal lamina xref: NIF_Subcellular:sao1397492660 ! Basal Lamina xref: EHDAA2:0003065 ! basal lamina xref: AEO:0000065 ! basal lamina xref: TGMA:0001850 ! basal lamina xref: MESH:A10.272.220 ! basement membrane is_a: UBERON:0000476 ! acellular anatomical structure relationship: adjacent_to UBERON:0000483 ! epithelium xref: AAO:0010269 ! basal lamina synonym: "lamina basalis" RELATED LATIN [Wikipedia:Basal_lamina] xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Basal_lamina.jpg xref: VHOG:0001592 ! basal lamina synonym: "basal laminae" RELATED PLURAL [VHOG:0001592] property_value: homology_notes "A basal lamina is certainly present in Bilateria and was evaluated as an autapomorphy of this taxon.[well established][VHOG]" xsd:string {external_class="VHOG:0001592", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.57", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0085872 [Term] id: UBERON:0011586 name: obsolete proteinaceous extracellular matrix comment: obsoleted as it was already present in GO is_obsolete: true !consider: VSAO:0000021 ! proteinaceous extracellular matrix consider: GO:0005578 ! proteinaceous extracellular matrix [Term] id: UBERON:0008883 name: osteoid def: "Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue" [Wikipedia:Osteoid, VSAO:0000046] comment: AO notes: Note that in VSAO this was classified both as tissue and acellular extracellular matrix. Consider also the AEO class 'bone condensation'. is_a intercellular matrix in FMA. synonym: "pre-bone" EXACT [PSPUB:0000170] synonym: "prebone" EXACT [VSAO:curator] synonym: "prebone tissue" EXACT [FMA:66830] is_a: UBERON:0002481 {source="VSAO"} ! bone tissue relationship: composed_primarily_of GO:0005578 ! proteinaceous extracellular matrix xref: FMA:66830 ! osteoid xref: XAO:0004035 ! osteoid xref: ncithesaurus:Osteoid ! Osteoid xref: SCTID:39365008 ! Osteoid tissue xref: VSAO:0000046 ! osteoid xref: http://upload.wikimedia.org/wikipedia/commons/9/9c/Active_osteoblasts.jpg property_value: external_definition "Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000046", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass proteinaceous extracellular matrix (VSAO:0000021)[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000046", date_retrieved="2012-08-14"} xref: galen:Osteoid ! osteoid xref: UMLS:C0682561 [Term] id: UBERON:0000483 name: epithelium def: "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]." [CARO:MAH, Wikipedia:Epithelium] subset: uberon_slim subset: vertebrate_core synonym: "epithelial tissue" EXACT [] synonym: "portion of epithelium" EXACT [FMA:9639] xref: AAO:0000144 ! epithelium xref: BILA:0000066 xref: BTO:0000416 xref: CARO:0000066 ! epithelium xref: FBbt:00007005 ! epithelium xref: FMA:9639 ! Portion of epithelium xref: GAID:402 ! epithelium xref: HAO:0000066 ! epithelium xref: VHOG:0000387 ! epithelium xref: TAO:0001486 ! epithelium xref: XAO:0003045 ! epithelium xref: ZFA:0001486 ! epithelium xref: ncithesaurus:Epithelium ! Epithelium xref: EHDAA2:0003066 ! epithelium xref: AEO:0000066 ! epithelium xref: MESH:A10.272 ! epithelium intersection_of: UBERON:0000119 ! cell layer intersection_of: has_part CL:0000066 ! epithelial cell union_of: UBERON:0000486 ! multilaminar epithelium union_of: UBERON:0000490 ! unilaminar epithelium relationship: has_part GO:0005911 ! cell-cell junction xref: AAO:0010055 ! epithelium xref: SCTID:31610004 ! Epithelium xref: http://upload.wikimedia.org/wikipedia/commons/c/c3/Tkanka_nablonkowa.png property_value: external_definition "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010055", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina.[CARO]" xsd:string {ontology="CARO", external_class="CARO:0000066", date_retrieved="2012-06-20", source="CARO:MAH", source="FMA:9639"} property_value: external_definition "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001486", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "The two basic types of metazoan tissue are epithelial and connective. The simplest metazoans, and developmental stages of many primitive invertebrates, consist solely of these two layers. Thus, epithelial and connective tissues may be the primary (original) tissues of metazoans, and both are important in the functional organization of animals.[well established][VHOG]" xsd:string {external_class="VHOG:0000387", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.59", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "epithelial" xsd:string xref: UMLS:C0014609 [Term] id: UBERON:0010077 ! cuboidal epithelium name: cuboidal epithelium def: "An epithelium consisting of cuboidal epithelial cells." [Wikipedia:Cuboidal_epithelium] comment: AO notes: in NCIT this is glandular. Editor notes: TODO - coordinate with CL, add cuboidal cell is_a: UBERON:0000483 ! epithelium xref: ncithesaurus:Cuboidal_Epithelium ! Cuboidal Epithelium xref: UMLS:C0682577 [Term] id: UBERON:0000484 name: simple cuboidal epithelium def: "Unilaminar epithelium that consists of a single layer of cuboidal cells." [CARO:MAH, Wikipedia:Simple_cuboidal_epithelium] comment: Editor notes: needs to be synchronized with CL - there is no distinct cuboidal cell in CL subset: uberon_slim subset: vertebrate_core synonym: "epithelium simplex cuboideum" EXACT [] xref: BILA:0000067 xref: CARO:0000067 ! simple cuboidal epithelium xref: FMA:45566 ! Simple cuboidal epithelium xref: HAO:0000067 ! simple cuboidal epithelium xref: TAO:0001497 ! simple cuboidal epithelium xref: ZFA:0001497 ! simple cuboidal epithelium xref: ncithesaurus:Simple_Cuboidal_Epithelium ! Simple Cuboidal Epithelium xref: EHDAA2:0003067 ! simple cuboidal epithelium xref: AEO:0000067 ! simple cuboidal epithelium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d0/Gray1133.png/200px-Gray1133.png is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0010077 ! cuboidal epithelium xref: AAO:0010064 ! simple cuboidal epithelium xref: XAO:0004009 ! simple cuboidal epithelium xref: http://upload.wikimedia.org/wikipedia/commons/d/d0/Gray1133.png xref: UMLS:C0836134 [Term] id: UBERON:0012274 ! columnar epithelium name: columnar epithelium def: "An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified]" [Wikipedia:Columnar_epithelium] is_a: UBERON:0000483 ! epithelium relationship: has_part CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: UBERON:0000485 name: simple columnar epithelium def: "Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]" [CARO:MAH, Wikipedia:Simple_columnar_epithelium, FMA:FMA] subset: uberon_slim subset: vertebrate_core synonym: "epithelium simplex columnare" EXACT [] synonym: "simple columnar epithelium" EXACT [] synonym: "columnar epithlium" BROAD [AEO:0000068] synonym: "columnar epithelium" BROAD [EHDAA2:0003068] xref: CARO:0000068 ! simple columnar epithlium xref: FMA:45567 ! Simple columnar epithelium xref: HAO:0000068 ! simple columnar epithelium xref: TAO:0001496 ! simple columnar epithelium xref: ZFA:0001496 ! simple columnar epithelium xref: ncithesaurus:Simple_Columnar_Epithelium ! Simple Columnar Epithelium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Gray1059.png/200px-Gray1059.png xref: FBbt:00007027 ! cuboidal/columnar epithelium xref: HAO:0000068 ! simple columnar epithelium xref: BILA:0000068 ! simple columnar epithlium xref: AEO:0000068 ! columnar epithlium is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0012274 ! columnar epithelium xref: AAO:0010063 ! simple columnar epithelium xref: XAO:0004008 ! simple columnar epithelium xref: EHDAA2_RETIRED:0003068 ! columnar epithelium xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray1059.png property_value: external_definition "Unilaminar epithelium that consists of a single layer of columnar cells.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010063", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Unilaminar epithelium that consists of a single layer of columnar cells.[CARO]" xsd:string {ontology="CARO", external_class="CARO:0000068", date_retrieved="2012-06-20", source="CARO:MAH", source="FMA:45567"} xref: SCTID:32210007 ! Columnar epithelium property_value: external_definition "Unilaminar epithelium that consists of a single layer of columnar cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001496", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0836135 [Term] id: UBERON:0000486 name: multilaminar epithelium def: "Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]" [CARO:MAH, Wikipedia:Stratified_epithelium, FMA:FMA] subset: uberon_slim subset: vertebrate_core synonym: "stratified epithelium" EXACT [] synonym: "laminated epithelium" RELATED [BTO:0002074] xref: BILA:0000069 xref: CARO:0000069 ! multilaminar epithelium xref: FMA:45562 ! Multilaminar epithelium xref: HAO:0000069 ! multilaminar epithelium xref: TAO:0001494 ! multilaminar epithelium xref: ZFA:0001494 ! multilaminar epithelium xref: ncithesaurus:Stratified_Epithelium ! Stratified Epithelium xref: BTO:0002074 ! stratified epithelium xref: EHDAA2:0003069 ! multilaminar epithelium xref: AEO:0000069 ! multilaminar epithelium is_a: UBERON:0000483 ! epithelium !disjoint_from: UBERON:0000490 ! unilaminar epithelium xref: AAO:0010059 ! multilaminar epithelium xref: SCTID:309044005 ! Multilaminar epithelium xref: XAO:0004006 ! multilaminar epithelium property_value: external_definition "Epithelium that consists of more than one layer of epithelial cells.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010059", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Epithelium that consists of more than one layer of epithelial cells.[CARO]" xsd:string {ontology="CARO", external_class="CARO:0000069", date_retrieved="2012-06-20", source="CARO:MAH", source="FMA:45562"} property_value: external_definition "Epithelium that consists of more than one layer of epithelial cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001494", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0682575 [Term] id: UBERON:0000487 name: simple squamous epithelium def: "Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]" [CARO:MAH, Wikipedia:Simple_squamous_epithelium, FMA:45565] subset: uberon_slim subset: vertebrate_core synonym: "epithelium simplex squamosum" EXACT [] xref: BILA:0000070 xref: CARO:0000070 ! simple squamous epithelium xref: FMA:45565 ! Simple squamous epithelium xref: HAO:0000070 ! simple squamous epithelium xref: TAO:0001498 ! simple squamous epithelium xref: ZFA:0001498 ! simple squamous epithelium xref: ncithesaurus:Simple_Squamous_Epithelium ! Simple Squamous Epithelium xref: EHDAA2:0003070 ! simple squamous epithelium xref: AEO:0000070 ! simple squamous epithelium xref: BTO:0002073 ! pavement epithelium (also: UBERON:0000490 'unilaminar epithelium') intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: has_part CL:0000076 ! squamous epithelial cell xref: AAO:0010066 ! simple squamous epithelium xref: XAO:0004010 ! simple squamous epithelium xref: http://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg property_value: external_definition "Unilaminar epithelium that consists of a single layer of squamous cells.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010066", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Unilaminar epithelium that consists of a single layer of squamous cells.[CARO]" xsd:string {ontology="CARO", external_class="CARO:0000070", date_retrieved="2012-06-20", source="CARO:MAH", source="FMA:45565"} property_value: external_definition "Unilaminar epithelium that consists of a single layer of squamous cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001498", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0836133 [Term] id: UBERON:0006914 ! squamous epithelium name: squamous epithelium def: "an epithelium characterised by its most superficial layer consisting of squamous epithelial cells." [Wikipedia:Squamous_epithelium] comment: consider FBbt:00007028 (squamous epithelium) A type of epithelium that is made up of flattened cells which are arranged with their long axes in the plane of the epithelium xref: BTO:0002072 ! squamous epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: has_part CL:0000076 ! squamous epithelial cell xref: ncithesaurus:Squamous_Epithelium ! Squamous Epithelium xref: SCTID:40118003 ! Squamous epithelium xref: UMLS:C0221909 [Term] id: UBERON:0006915 ! stratified squamous epithelium name: stratified squamous epithelium def: "Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA]" [FMA:45563, Wikipedia:Stratified_squamous_epithelium] synonym: "epithelium stratificatum squamosum" EXACT [FMA:45563] xref: FMA:45563 ! stratified squamous epithelium intersection_of: UBERON:0000486 ! multilaminar epithelium intersection_of: has_part CL:0000076 ! squamous epithelial cell xref: ncithesaurus:Stratified_Squamous_Epithelium ! Stratified Squamous Epithelium xref: UMLS:C0836131 [Term] id: UBERON:0010304 name: non-keratinized stratified squamous epithelium def: "Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus." [FMA:45569, Wikipedia:Stratified_squamous_epithelium#Nonkeratinized] synonym: "epithelium stratificatum squamosum noncornificatum" EXACT [FMA:45569] synonym: "nonkeratinizing stratified squamous epithelium" EXACT [FMA:45569] is_a: UBERON:0006915 {source="FMA"} ! stratified squamous epithelium xref: FMA:45569 ! nonkeratinizing stratified squamous epithelium [Term] id: UBERON:0012329 name: keratinized stratified squamous epithelium def: "Keratinized stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesize and accumulate keratin." [FMA:45568, Wikipedia:Stratified_squamous_epithelium#Keratinized] synonym: "epithelium stratificatum squamosum cornificatum" EXACT LATIN [FMA:45568] intersection_of: UBERON:0006915 ! stratified squamous epithelium intersection_of: has_part GO:0045095 ! keratin filament disjoint_from: UBERON:0010304 ! nonkeratinizing stratified squamous epithelium xref: FMA:45568 ! keratinized stratified squamous epithelium [Term] id: UBERON:0000488 name: atypical epithelium def: "Epithelium that consists of epithelial cells not arranged in one ore more layers." [CARO:MAH] subset: vertebrate_core synonym: "heterogenous epithelium" EXACT [] xref: BILA:0000071 xref: CARO:0000071 ! atypical epithelium xref: FMA:61741 ! Atypical epithelium xref: HAO:0000071 ! atypical epithelium xref: TAO:0001493 ! atypical epithelium xref: ZFA:0001493 ! atypical epithelium xref: EHDAA2:0003071 ! atypical epithelium xref: AEO:0000071 ! atypical epithelium is_a: UBERON:0000483 ! epithelium xref: AAO:0010057 ! atypical epithelium xref: XAO:0004004 ! atypical epithelium property_value: external_definition "Epithelium that consists of epithelial cells not arranged in one or more layers.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001493", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0007601 name: ciliated epithelium def: "Epithelium bearing vibratile cilia on the free surface." [http://medical-dictionary.thefreedictionary.com/ciliated+epithelium] intersection_of: UBERON:0000483 ! epithelium intersection_of: has_part CL:0000067 ! ciliated epithelial cell [Term] id: UBERON:0007602 name: stratified columnar epithelium def: "Stratified columnar epithelia is a rare type of epithelial tissue composed of column shaped cells arranged in multiple layers. Stratified columnar epithelia are found in the ocular conjunctiva of the eye, in parts of the pharynx and anus, the female's uterus, the male urethra and vas deferens. Also found in intralobular ducts in salivary glands.[WP]" [Wikipedia:Stratified_columnar_epithelia] synonym: "epithelium stratificatum columnare" EXACT [FMA:45564] xref: FMA:45564 ! stratified columnar epithelium is_a: UBERON:0000486 {source="FMA"} ! multilaminar epithelium is_a: UBERON:0012274 ! columnar epithelium xref: ncithesaurus:Stratified_Columnar_Epithelium ! Stratified Columnar Epithelium xref: UMLS:C0836132 [Term] id: UBERON:0007603 name: stratified cuboidal epithelium def: "Stratified cuboidal epithelia is a rare type of epithelial tissue composed of cuboidally shaped cells arranged in multiple layers. They protect areas such as ducts of sweat glands, mammary glands, and salivary glands." [Wikipedia:Stratified_cuboidal_epithelium] synonym: "epithelium stratificatum cuboideum" EXACT [FMA:63912] xref: FMA:63912 ! stratified cuboidal epithelium is_a: UBERON:0000486 {source="FMA"} ! multilaminar epithelium is_a: UBERON:0010077 ! cuboidal epithelium xref: ncithesaurus:Stratified_Cuboidal_Epithelium ! Stratified Cuboidal Epithelium xref: http://upload.wikimedia.org/wikipedia/commons/1/18/Gray940.png xref: UMLS:C0932055 [Term] id: UBERON:0007592 ! ciliated columnar epithelium name: ciliated columnar epithelium def: "Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA]" [FMA:64798] xref: FMA:64798 ! ciliated columnar epithelium is_a: UBERON:0000485 {source="FMA"} ! simple columnar epithelium intersection_of: UBERON:0000485 ! simple columnar epithelium intersection_of: has_part CL:0000067 ! ciliated epithelial cell [Term] id: UBERON:0007606 name: ciliated stratified columnar epithelium xref: FMA:67521 ! ciliated stratified columnar epithelium is_a: UBERON:0007602 {source="FMA"} ! stratified columnar epithelium intersection_of: UBERON:0007602 ! stratified columnar epithelium intersection_of: has_part CL:0000067 ! ciliated epithelial cell [Term] id: UBERON:0006934 ! sensory epithelium name: sensory epithelium def: "Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue." [BTO:0000314] comment: note that the definition sourced from Dorlands say 'simple columnar', but FMA says atypical synonym: "neuroepithelium" RELATED INCONSISTENT [BTO:0000314] xref: FMA:62410 ! sensory epithelium is_a: UBERON:0000488 ! atypical epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: has_part CL:0000098 ! sensory epithelial cell disjoint_from: UBERON:0004022 ! embryonic neuroepithelium relationship: part_of UBERON:0000010 ! peripheral nervous system xref: SCTID:309045006 ! Sensory epithelium [Term] id: UBERON:0000489 name: cavitated compound organ def: "Compound organ that contains one or more macroscopic anatomical spaces." [CARO:MAH] subset: upper_level xref: BILA:0000072 xref: CARO:0000072 ! cavitated compound organ xref: HAO:0000072 ! cavitated compound organ xref: TAO:0001490 ! cavitated compound organ xref: XAO:0003165 ! cavitated compound organ xref: ZFA:0001490 ! cavitated compound organ xref: EHDAA2:0003072 ! cavitated compound organ xref: AEO:0000072 ! cavitated compound organ xref: TGMA:0001857 ! cavitated compound organ xref: FMA:55671 ! cavitated organ synonym: "cavitated organ" EXACT [FMA:55671] intersection_of: UBERON:0003103 ! compound organ intersection_of: has_part UBERON:0002553 ! anatomical cavity xref: AAO:0010016 ! cavitated compound organ subset: organ_slim xref: VHOG:0001730 ! cavitated compound organ [Term] id: UBERON:0000490 name: unilaminar epithelium def: "Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]" [CARO:MAH, FMA:45561] comment: AO/editor notes: consider adding disjointness axiom between unilaminar and multilaminar - but note that this will render EHDAA2:0003244 (chorionic trophoblast) unsatisfiable subset: vertebrate_core synonym: "simple epithelium" EXACT [FMA:45561] xref: BILA:0000073 xref: CARO:0000073 ! unilaminar epithelium xref: FMA:45561 ! Unilaminar epithelium xref: HAO:0000073 ! unilaminar epithelium xref: TAO:0001495 ! unilaminar epithelium xref: ZFA:0001495 ! unilaminar epithelium xref: ncithesaurus:Simple_Epithelium ! Simple Epithelium xref: EHDAA2:0003073 ! unilaminar epithelium xref: AEO:0000073 ! unilaminar epithelium xref: BTO:0002073 ! pavement epithelium (also: UBERON:0000487 'simple squamous epithelium') is_a: UBERON:0000483 ! epithelium !disjoint_from: UBERON:0000486 ! multilaminar epithelium xref: AAO:0010062 ! unilaminar epithelium xref: SCTID:309043004 ! Unilaminar epithelium xref: XAO:0004007 ! unilaminar epithelium property_value: external_definition "Epithelium that consists of a single layer of epithelial cells.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010062", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Epithelium that consists of a single layer of epithelial cells.[CARO]" xsd:string {ontology="CARO", external_class="CARO:0000073", date_retrieved="2012-06-20", source="CARO:MAH", source="FMA:45561"} property_value: external_definition "Epithelium that consists of a single layer of epithelial cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001495", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0682574 [Term] id: UBERON:0000491 name: solid compound organ def: "Compound organ that does not contain macroscopic anatomical spaces." [CARO:MAH] subset: upper_level xref: BILA:0000074 xref: CARO:0000074 ! solid compound organ xref: HAO:0000074 ! solid compound organ xref: TAO:0001491 ! solid compound organ xref: XAO:0003164 ! solid compound organ xref: ZFA:0001491 ! solid compound organ xref: EHDAA2:0003074 ! solid compound organ xref: AEO:0000074 ! solid compound organ xref: TGMA:0001859 ! solid compound organ is_a: UBERON:0003103 ! compound organ xref: AAO:0010019 ! solid compound organ subset: organ_slim [Term] id: UBERON:0003891 ! stroma name: stroma def: "Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma." [Wikipedia:Stroma_of_ovary_%28animal_tissue%29] xref: FMA:81494 ! Stroma xref: ncithesaurus:Stroma_Connective_Tissue ! Stroma is_a: UBERON:0002384 ! connective tissue subset: grouping_class property_value: has_relational_adjective "stromal" xsd:string xref: UMLS:C0927195 [Term] id: UBERON:0005169 name: interstitial tissue def: "connective tissue between the cellular elements of a structure." [http://medical-dictionary.thefreedictionary.com/tissue] comment: Editors note: specify differentia from stroma synonym: "interstitium" EXACT [] xref: FMA:86301 ! Interstitium is_a: UBERON:0003891 {source="FMA"} ! stroma xref: SCTID:85293002 ! Interstitial tissue property_value: has_relational_adjective "interstital" xsd:string [Term] id: UBERON:0002473 name: intercerebral commissure def: "Class of unpaired telencephalic white matter structures consisting of fiber pathways which project across the midsagittal plane and which serve to interconnect telencephalic structures lying within the contralateral cerebral hemisphere[FMA]." [FMA:67930] synonym: "interhemispheric commissure" RELATED [MA:0002721] synonym: "brain commissure" NARROW [] xref: FMA:67930 ! Intercerebral commissure xref: MA:0002721 ! intercerebral commissure is_a: UBERON:0001020 ! commissure relationship: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0002437 ! cerebral white matter [Term] id: UBERON:0005341 ! ventral commissure name: ventral commissure def: "the fiber tracts that connect the ventral region of the two cerebral hemispheres and span the longitudinal fissure, including the anterior and the habenular commissures[MP]." [MP:0008220] is_a: UBERON:0001020 ! commissure [Term] id: UBERON:0000935 name: anterior commissure def: "bundle of nerve fibers (white matter), connecting the two cerebral hemispheres across the midline, and placed in front of the columns of the fornix. The great majority of fibers connecting the two hemispheres travel through the corpus callosum, which is over 10 times larger than the anterior commissure, and other routes of communication pass through the hippocampal commissure or, indirectly, via subcortical connections. Nevertheless, the anterior commissure is a significant pathway that can be clearly distinguished in the brains of all mammals." [Wikipedia:Anterior_commissure] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "commissura anterior" RELATED [] synonym: "commissura rostral" RELATED [] synonym: "commissura rostralis" EXACT [] synonym: "precommisure" RELATED [Wikipedia:Anterior_commisure] synonym: "rostral commissure" RELATED [] xref: FMA:61961 ! Anterior commissure xref: MA:0002722 ! anterior commissure xref: TAO:0001108 ! anterior commissure xref: ZFA:0001108 ! anterior commissure xref: ncithesaurus:Anterior_Commissure ! Anterior Commissure xref: BTO:0002169 ! anterior commissure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b4/Gray744.png/200px-Gray744.png xref: EMAPA:19038 ! anterior commissure xref: BM:Tel-AC ! anterior commissure is_a: UBERON:0002473 {source="MA", source="FMA"} ! intercerebral commissure xref: SCTID:369119009 ! Entire anterior commissure xref: NIF_GrossAnatomy:Class_4 ! Anterior commissure xref: NIF_GrossAnatomy:birnlex_1557 ! Anterior commissure synonym: "commissura anterior" RELATED LATIN [Wikipedia:Anterior_commissure] xref: http://upload.wikimedia.org/wikipedia/commons/b/b4/Gray744.png xref: VHOG:0001558 ! anterior commissure property_value: homology_notes "In all vertebrates the thin structure that connects the two halves of the telencephalon shows a ridge-like thickening at the basal side known as the anterior commissure.[well established][VHOG]" xsd:string {external_class="VHOG:0001558", ontology="VHOG", source="DOI:10.1111/j.1749-6632.1969.tb20432.x", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0152335 [Term] id: UBERON:0001909 name: habenular commissure def: "The habenular commissure, is a brain commissure (a band of nerve fibers) situated in front of the pineal gland that connects the habenular nucleus on one side of the diencephalon with that on the other side. The habernular commissure is part of the trigonum habenulæ (a small depressed triangular area situated in front of the superior colliculus and on the lateral aspect of the posterior part of the tænia thalami). The trigonum habenulæ also contains groups of nerve cells termed the ganglion habenulæ. Fibers enter the trigonum habenulæ from the stalk of the pineal gland, and the habenular commissure. Most of the trigonum habenulæ's fibers are, however, directed downward and form a bundle, the fasciculus retroflexus of Meynert, which passes medial to the red nucleus, and, after decussating with the corresponding fasciculus of the opposite side, ends in the interpeduncular ganglion. Nerve cell fibers enter the trigonum habenulæ from the stalk of the pineal body, and the habernular commissure. [WP,unvetted]." [Wikipedia:Habenular_commissure] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "commissura habenularum" EXACT [ZFA:0000359] synonym: "commissure habenularum" EXACT [MP:0008231] xref: FMA:62048 ! Habenular commissure xref: NIF_GrossAnatomy:birnlex_1609 ! Habenular commissure xref: TAO:0000359 ! habenular commissure xref: ZFA:0000359 ! habenular commissure xref: BM:Die-Epi-HC ! habenular commissure is_a: UBERON:0005341 ! ventral commissure relationship: part_of UBERON:0001904 ! habenula xref: SCTID:279335009 ! Entire habenular commissure synonym: "commissura habenularum" RELATED LATIN [Wikipedia:Habenular_commissure] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png [Term] id: UBERON:0000936 name: posterior commissure def: "Rounded band of white fibers crossing the middle line on the dorsal aspect of the upper end of the cerebral aqueduct. It is important in the bilateral pupillary light reflex. Its fibers acquire their medullary sheaths early, but their connections have not been definitely determined. Most of them have their origin in a nucleus, the nucleus of the posterior commissure (nucleus of Darkschewitsch), which lies in the central gray substance of the upper end of the cerebral aqueduct, in front of the nucleus of the oculomotor nerve. Some are probably derived from the posterior part of the thalamus and from the superior colliculus, whereas others are believed to be continued downward into the medial longitudinal fasciculus. The posterior commissure interconnects the pretectal nuclei, mediating the consensual pupillary light reflex[WP].Diencephalic tract which is located in the vicinity of the dorsal diencephalon and mesencephalon and connects the pretectal nuclei. From Neuroanatomy of the Zebrafish Brain[ZFA]." [Wikipedia:Posterior_commissure, ZFA:0000320] comment: AO notes: part_of brainstem in MA; midbrain tectum in NIF subset: uberon_slim subset: vertebrate_core synonym: "caudal commissure" EXACT [FMA:62072, ZFA:0000320] synonym: "epithalamic commissure" EXACT [FMA:62072] xref: FMA:62072 ! Posterior commissure xref: MA:0002743 ! posterior commissure xref: NIF_GrossAnatomy:birnlex_1026 ! Posterior commissure xref: TAO:0000320 ! caudal commissure xref: ZFA:0000320 ! caudal commissure xref: ncithesaurus:Posterior_Commissure ! Posterior Commissure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d7/Gray715.png/200px-Gray715.png xref: BM:MB-Tec-PC ! posterior commissure is_a: UBERON:0001020 ! commissure relationship: part_of UBERON:0001894 {source="FMA"} ! diencephalon relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata synonym: "commissura posterior" RELATED LATIN [Wikipedia:Posterior_commissure] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png xref: UMLS:C0152327 [Term] id: UBERON:0005340 ! dorsal telencephalic commissure name: dorsal telencephalic commissure def: "the fiber tracts that connect the dorsal region of the two cerebral hemispheres and span the longitudinal fissure, including the corpus callosum and hippocampal commissure[MP]." [MP:0008219] synonym: "dorsal commissure" EXACT [MP:0008219] is_a: UBERON:0001020 ! commissure [Term] id: UBERON:0000908 name: hippocampal commissure alt_id: UBERON:Commissure-MA_0002723 def: "The lateral portions of the body of the fornix are joined by a thin triangular lamina, named the psalterium (lyra). This lamina contains some transverse fibers that connect the two hippocampi across the middle line and constitute the commissure of fornix (hippocampal commissure)." [Wikipedia:Commissure_of_fornix] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "commissure of fornix" RELATED [Wikipedia:Commissure_of_fornix] synonym: "commissure of fornix of forebrain" EXACT [FMA:61970] synonym: "dorsal hippocampal commissure" EXACT [FMA:61970] synonym: "fornical commissure" EXACT [FMA:61970] synonym: "fornix commissure" EXACT [FMA:61970] synonym: "hippocampus commissure" EXACT [MP:0008221] synonym: "delta fornicis" EXACT [MP:0008221] xref: MA:0002723 ! hippocampal commissure xref: FMA:61970 ! Commissure of fornix of forebrain xref: NIF_GrossAnatomy:birnlex_746 ! Commissure of fornix xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/21/Gray747.png/200px-Gray747.png is_a: UBERON:0005340 ! dorsal telencephalic commissure relationship: part_of UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0002437 ! cerebral white matter synonym: "commissura hippocampi" EXACT LATIN [FMA:TA, FMA:61970] xref: SCTID:369115003 ! Entire hippocampal commissure xref: http://upload.wikimedia.org/wikipedia/commons/2/21/Gray747.png [Term] id: UBERON:0002336 name: corpus callosum def: "The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres[GO]." [Wikipedia:Corpus_callosum] subset: uberon_slim xref: BTO:0000615 xref: FMA:86464 ! Corpus callosum xref: GAID:683 ! corpus callosum xref: MA:0000188 ! corpus callosum xref: MAT:0000286 ! corpus callosum xref: MIAA:0000286 ! corpus callosum xref: NIF_GrossAnatomy:birnlex_1087 ! Corpus callosum xref: OpenCyc:Mx4rvbNzdZwpEbGdrcN5Y29ycA xref: ncithesaurus:Corpus_Callosum ! Corpus Callosum xref: EFO:0001390 ! corpus callosum xref: OpenCyc:Mx4rvbNzdZwpEbGdrcN5Y29ycA ! corpus callosum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Gray733.png/200px-Gray733.png xref: MESH:A08.186.211.730.885.362 ! corpus callosum xref: EV:0100305 ! corpus callosum xref: BM:Tel-CC ! corpus callosum is_a: UBERON:0002473 {source="MA", source="FMA"} ! intercerebral commissure is_a: UBERON:0005340 ! dorsal telencephalic commissure relationship: never_in_taxon NCBITaxon:9255 ! Monotremata relationship: only_in_taxon NCBITaxon:9347 {source="Wikipedia"} ! Eutheria xref: SCTID:362354006 ! Entire corpus callosum xref: http://upload.wikimedia.org/wikipedia/commons/a/aa/Gray733.png xref: VHOG:0001608 ! corpus callosum property_value: external_definition "The largest commissure of the brain connecting the cerebral hemispheres. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001608", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/corpus+callosum", source="http://bgee.unil.ch/"} property_value: homology_notes "In addition to the anterior commissure, placental mammals have a phylogenetically new forebrain commissure, the corpus callosum, which primarily interconnects the neocortex of the cerebral hemispheres.[well established][VHOG]" xsd:string {external_class="VHOG:0001608", ontology="VHOG", source="DOI:10.1111/j.1749-6632.1969.tb20447.x Ebner FF\, A comparison of primitive forebrain organization in metatherian and eutherian mammals. Annals of the New York Academy of Sciences (1969)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: taxon_notes "The corpus callosum is found only in placental mammals. other groups do have other brain structures that allow for communication between the two hemispheres, such as the anterior commissure, which serves as the primary mode of interhemispheric communication in marsupials." xsd:string {source="http://en.wikipedia.org/wiki/Corpus_callosum#Species_Differences"} xref: UMLS:C0010090 [Term] id: UBERON:0012112 name: ingested food comment: AO notes: FMA def restricts this to 'oral cavity, pharynx or esophagus', but child terms includes chyme - which is in the stomach is_a: UBERON:0000463 {source="FMA"} ! portion of organism substance xref: FMA:62964 ! ingested food property_value: external_definition "Body substance, which consists of food admixed with saliva contained in the oral cavity, pharynx or esophagus[FMA]." xsd:string {ontology="FMA", external_class="FMA:62964"} [Term] id: UBERON:0000910 name: chyme def: "Chyme is a bodily fluid consisting of a liquid substance found in the stomach before passing through the pyloric valve and entering the duodenum. It results from the mechanical and chemical breakdown of a bolus and consists of partially digested food, water, hydrochloric acid, and various digestive enzymes." [Wikipedia:Chyme] synonym: "chymus" EXACT [ENVO:02000026] xref: ENVO:02000026 xref: FMA:62961 ! Chyme is_a: UBERON:0012112 {source="FMA"} ! ingested food [Term] id: UBERON:0012113 name: bolus of food def: "Ingested food contained in the esophagus." [FMA:78441, Wikipedia:Bolus_(digestion)] synonym: "bolus" BROAD [] synonym: "food bolus" EXACT [FMA:78441] synonym: "bolus of ingested food" EXACT [FMA:78441] is_a: UBERON:0012112 {source="FMA"} ! ingested food xref: FMA:78441 ! bolus of ingested food [Term] id: UBERON:0012114 name: cud def: "a bolus of semi-degraded food regurgitated from the reticulorumen of a ruminant, produced during the physical digestive process of rumination" [Wikipedia:Cud] synonym: "bolus of cud" RELATED [] intersection_of: UBERON:0012113 ! bolus of ingested food intersection_of: output_of GO:0036147 ! rumination xref: SCTID:110606000 ! Cud [Term] id: UBERON:0000911 name: chyle def: "Chyle is a bodily fluid consisting of a milky fluid consisting of lymph and emulsified fats; formed in the small intestine during digestion of ingested fats." [http://wordnet.princeton.edu/perl/webwn?s=chyle, Wikipedia:Chyle] xref: ENVO:02000030 xref: FMA:61403 ! Chyle xref: GAID:1187 ! chyle xref: MESH:A12.207.630.350 ! chyle is_a: UBERON:0000463 ! portion of organism substance relationship: has_part UBERON:0002391 ! lymph xref: ncithesaurus:Chyle ! chyle xref: UMLS:C0008730 [Term] id: UBERON:0000912 ! mucus name: mucus def: "Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water." [Wikipedia:Mucus] xref: ENVO:02000040 xref: FMA:66938 ! Mucus xref: OpenCyc:Mx4rvVjHq5wpEbGdrcN5Y29ycA xref: ncithesaurus:Mucus ! Mucus xref: GAID:1164 ! mucus xref: galen:Mucus ! mucus xref: OpenCyc:Mx4rvVjHq5wpEbGdrcN5Y29ycA ! mucus xref: MESH:A12.200.503 ! mucus is_a: UBERON:0000456 ! bodily secretion relationship: secreted_by UBERON:0000344 ! mucosa property_value: has_relational_adjective "mucoid" xsd:string property_value: has_relational_adjective "mucous" xsd:string xref: UMLS:C0026727 [Term] id: UBERON:0000913 name: interstitial fluid def: "Interstitial fluid is a bodily fluid consisting of a solution which bathes and surrounds the cells of multicellular animals. It is the main component of the extracellular fluid, which also includes plasma and transcellular fluid." [FMA:9673, Wikipedia:Interstitial_fluid] synonym: "intercellular fluid" EXACT [ENVO:02000042] synonym: "tissue fluid" EXACT [ENVO:02000042] xref: ENVO:02000042 xref: FMA:9673 ! Tissue fluid is_a: UBERON:0000463 ! portion of organism substance [Term] id: UBERON:0001443 name: chest def: "Subdivision of trunk proper, which is demarcated from the neck by the plane of the superior thoracic aperture and from the abdomen internally by the inferior surface of the diaphragm and externally by the costal margin and associated with the thoracic vertebral column and ribcage and from the back of the thorax by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines; together with the abdomen and the perineum, it constitutes the trunk proper[FMA]." [Wikipedia:Chest, FMA:9576] comment: editor note - FMA:24216 present in FMA1, but gone in subsequent versions subset: uberon_slim synonym: "anterior thoracic region" EXACT [] synonym: "anterolateral part of thorax" EXACT [] synonym: "front of thorax" EXACT [] synonym: "ventral part of thoracic region" EXACT [] synonym: "anterior chest" EXACT [FMA:24816] synonym: "front of chest" EXACT [FMA:24816] synonym: "thorax" RELATED [FMA:9576] xref: galen:Chest xref: MA:0000031 ! chest xref: OpenCyc:Mx4rvVikFZwpEbGdrcN5Y29ycA xref: FMA:9576 ! thorax xref: ncithesaurus:Chest ! Chest xref: EFO:0000965 ! thorax xref: MAT:0000295 ! thorax xref: MIAA:0000295 ! thorax xref: ncithesaurus:Thorax ! Thorax xref: EFO:0000965 ! thorax xref: galen:Thorax ! thorax xref: MESH:A01.911 ! thorax xref: GAID:91 ! thorax xref: EV:0100010 ! thorax xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Chest.jpg/200px-Chest.jpg xref: BTO:0001368 ! thorax is_a: UBERON:0009569 {source="FMA-modified"} ! subdivision of trunk relationship: part_of UBERON:0000915 {source="FMA", source="MA"} ! thoracic segment of trunk relationship: spatially_disjoint_from UBERON:0000916 ! abdomen synonym: "pectus" EXACT LATIN [FMA:TA, FMA:24816] synonym: "thorax" RELATED LATIN [Wikipedia:Chest] xref: http://upload.wikimedia.org/wikipedia/commons/d/db/Chest.jpg synonym: "thoracic body wall" RELATED [MA:0000031] xref: UMLS:C1527391 xref: UMLS:C0817096 [Term] id: UBERON:0005482 name: obsolete region of thorax is_obsolete: true synonym: "thoracic region" EXACT [FMA:20358] synonym: "thoracic subdivision" EXACT [FMA:20358] synonym: "subdivision of thorax" EXACT [FMA:20358] consider: FMA:20358 ! Subdivision of thorax consider: SCTID:425803006 ! Region of thorax [Term] id: UBERON:0000915 name: thoracic segment of trunk def: "Organismal subdivision of body that lies between the head and the abdomen [Wikipedia]." [Wikipedia:Thorax] comment: Usage notes: note that we use the slightly verbose term 'thoracic segment of trunk' to avoid confusuon with insect thorax. todo - taxonomic constraints. Also, in FMA 'thorax' is a synonym for chest subset: uberon_slim synonym: "upper body" RELATED [] synonym: "thorax" RELATED [MA:0000022] xref: FMA:259209 ! thoracic segment of trunk xref: MA:0000022 ! thoracic segment of trunk is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk is_a: UBERON:0011676 ! axial subdivision of organism relationship: spatially_disjoint_from UBERON:0000033 ! head relationship: spatially_disjoint_from UBERON:0002417 ! abdominal segment of trunk relationship: spatially_disjoint_from UBERON:0000026 ! appendage xref: SCTID:302551006 ! Entire thorax [Term] id: UBERON:0002417 ! abdominal segment of trunk name: abdominal segment of trunk def: "the abdominal segment of the torso." [Wikipedia:Lumbar] synonym: "abdomen/pelvis/perineum" RELATED [MA:0000021] synonym: "lower body" RELATED [MA:0000021] synonym: "lumbar region" RELATED [UBERON:cjm] xref: FMA:259211 ! Abdominal segment of trunk xref: MA:0000021 ! abdominal segment of trunk is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk is_a: UBERON:0011676 ! axial subdivision of organism xref: SCTID:362875007 ! Entire lower body [Term] id: UBERON:0000916 name: abdomen def: "In vertebrates such as mammals the abdomen (belly) constitutes the part of the body between the thorax (chest) and pelvis. The region enclosed by the abdomen is termed the abdominal cavity." [Wikipedia:Abdomen] comment: Taxon notes: Vertebrate specific. In arthropods 'abdomen' is the most distal section of the body which lies behind the thorax or cephalothorax. If need be we can introduce some grouping class subset: uberon_slim synonym: "celiac region" RELATED [] synonym: "adult abdomen" RELATED [] synonym: "belly" RELATED [] synonym: "abdominopelvic region" EXACT [FMA:9577] synonym: "abdominopelvis" EXACT [FMA:9577] xref: BTO:0000020 xref: FMA:9577 ! Abdomen xref: GAID:16 ! abdomen xref: galen:Abdomen xref: MA:0000029 ! abdomen xref: MAT:0000298 ! abdomen xref: MIAA:0000298 ! abdomen xref: OpenCyc:Mx4rvVjgyZwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvVjgyZwpEbGdrcN5Y29ycA ! abdomen xref: MESH:A01.047 ! abdomen xref: EV:0100011 ! abdomen xref: EFO:0000968 ! abdomen is_a: UBERON:0009569 ! subdivision of trunk relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002417 {source="MA"} ! abdominal segment of trunk xref: SCTID:302553009 ! Entire abdomen property_value: has_relational_adjective "abdominal" xsd:string [Term] id: UBERON:0005462 name: lower back def: "Subdivision of abdominal segment of trunk which in humans is demarcated from the front of the abdomen by the posterior surface of the anterior layer of the thoracolumbar fascia and the anterior surface of the lumbar vertebral column; together with the front of the abdomen, it constitutes the abdomen[Modified from FMA]." [FMA:61681] comment: overlaps with region sometimes called 'loin' synonym: "abdominal back" EXACT [FMA:61681] synonym: "dorsum of abdomen" EXACT [FMA:61681] synonym: "lumbar part of back" EXACT [FMA:61681] synonym: "lumbar region of back" EXACT [UBERON:cjm] synonym: "lumbar region" BROAD [FMA:61681] synonym: "posterior part of abdomen" EXACT [FMA:61681] synonym: "back of abdomen" EXACT [FMA:61681] synonym: "lower back" EXACT [MA:0000027] synonym: "loin" RELATED [Wikipedia:Loin, BTO:0001505] xref: BTO:0001505 ! loin xref: FMA:61681 ! Back of abdomen xref: MA:0000027 ! lower back is_a: UBERON:0009569 ! subdivision of trunk relationship: part_of UBERON:0002417 {source="MA"} ! abdominal segment of trunk relationship: part_of UBERON:0001137 ! dorsum synonym: "regio lumbalis" EXACT LATIN [FMA:TA, FMA:61681] xref: ncithesaurus:Lumbar_Region ! Lumbar Region xref: SCTID:182343007 ! Entire lumbar region xref: UMLS:C0024090 [Term] id: UBERON:0000917 name: obsolete abdominal segment synonym: "segment of abdomen" EXACT [OBOL:automatic] consider: FBbt:00000021 ! abdominal segment consider: HAO:0000016 ! abdominal segment consider: SPD:0000055 ! abdominal segment is_obsolete: true consider: UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0000918 name: obsolete yolk def: "The nutritive substance contained in the egg." [FB:gg] synonym: "vegetal yolk mass" BROAD [] synonym: "yolk cell" RELATED [] consider: FBbt:00000035 ! yolk xref: MAT:0000335 ! yolk xref: MIAA:0000335 ! yolk consider: XAO:0000281 ! vegetal yolk mass consider: ZFA:0000084 ! yolk consider: GO:0060417 ! yolk consider: BTO:0000371 ! egg yolk is_obsolete: true consider: UBERON:0007378 ! egg yolk consider: GO:0060417 ! yolk [Term] id: UBERON:0000919 name: obsolete lipid droplet consider: FBbt:00000037 ! lipid droplet consider: FMA:62962 ! Lipid droplet consider: GO:0005811 ! lipid particle is_obsolete: true replaced_by: GO:0005811 ! lipid particle [Term] id: UBERON:0000920 ! egg chorion name: egg chorion def: "A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish [GO]." [GO:0042600, Wikipedia:Chorion_(egg)] subset: uberon_slim subset: dubious_grouping subset: vertebrate_core synonym: "chorion (egg)" EXACT [] synonym: "chorion" RELATED [] xref: FBbt:00000038 ! chorion xref: TAO:0000329 ! chorion xref: ZFA:0000329 ! chorion xref: TGMA:0000681 ! chorion is_a: UBERON:0000476 ! acellular anatomical structure is_a: UBERON:0000478 ! extraembryonic structure disjoint_from: UBERON:0003124 ! chorion relationship: surrounds UBERON:0003125 ! vitelline membrane property_value: external_definition "The egg shell. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000329", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0000921 name: obsolete pronucleus def: "." [Wikipedia:Pronucleus] consider: FBbt:00000048 ! pronucleus consider: FMA:84673 ! Pronucleus consider: GO:0045120 ! pronucleus is_obsolete: true replaced_by: GO:0045120 ! pronucleus [Term] id: UBERON:0010316 ! germ layer / neural crest name: germ layer / neural crest is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0000479 {source="GO", source="ZFA"} ! tissue relationship: develops_from UBERON:0002532 ! epiblast [Term] id: UBERON:0000923 name: germ layer def: "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." [Wikipedia:Germ_layer] comment: Classically the germ layers are ectoderm, mesoderm and endoderm. Alternatively: primary = ectoderm, endoderm; secondary=mesoderm; tertiary=dorsal mesoderm, NC[UBERONREF:0000002] subset: uberon_slim subset: vertebrate_core synonym: "embryonic germ layer" RELATED [] synonym: "embryonic germ layers" RELATED [] synonym: "embryonic tissue" BROAD [FMA:69069] synonym: "germinal layer" EXACT [ncithesaurus:Germinal_Layer] synonym: "primary germ layer" NARROW [GO:0001704, ZFA:0001122] xref: AAO:0000480 ! primary_germ_layer xref: BILA:0000035 xref: BTO:0000556 xref: FBbt:00000110 ! germ layer xref: FMA:69069 ! Embryonic tissue xref: GAID:1303 ! germ layer xref: VHOG:0001223 ! primary germ layer xref: TAO:0001122 ! primary germ layer xref: XAO:0003011 ! primary germ layer xref: ZFA:0001122 ! primary germ layer xref: ncithesaurus:Germinal_Layer xref: ncithesaurus:Embryonic_Tissue ! Embryonic Tissue xref: MESH:A16.254.425 ! germ layer is_a: UBERON:0010316 ! germ layer / neural crest relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0002532 ! epiblast property_value: homology_notes "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001223", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) Limb development and evolution\, p.722", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0920502 xref: UMLS:C1708239 [Term] id: UBERON:0000924 name: ectoderm def: "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." [Wikipedia:Ectoderm] subset: uberon_slim subset: vertebrate_core synonym: "embryonic ectoderm" EXACT [VHOG:0000153] xref: AAO:0000137 ! ectoderm xref: BILA:0000036 xref: BTO:0000315 xref: EFO:0000414 ! ectoderm xref: FBbt:00000111 ! ectoderm xref: FMA:69070 ! Ectoderm xref: GAID:1304 ! ectoderm xref: MAT:0000155 ! ectoderm xref: MAT:0000173 ! ectoderm xref: MIAA:0000173 ! ectoderm xref: TAO:0000016 ! ectoderm xref: XAO:0000001 ! ectoderm xref: ZFA:0000016 ! ectoderm xref: VHOG:0000153 ! embryonic ectoderm xref: ncithesaurus:Ectoderm ! Ectoderm xref: EHDAA2:0000428 ! ectoderm xref: MESH:A16.254.425.273 ! ectoderm xref: EMAPA:16069 ! ectoderm of embryo xref: EV:0100003 ! ectoderm is_a: UBERON:0000923 ! germ layer relationship: has_part CL:0000221 ! ectodermal cell relationship: develops_from UBERON:0006601 {source="cjm"} ! presumptive ectoderm xref: SCTID:362851007 ! Entire ectoderm xref: http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png property_value: external_definition "Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000137", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000153", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) Limb development and evolution\, p.722", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "ectodermal" xsd:string xref: UMLS:C0013574 [Term] id: UBERON:0000925 name: endoderm def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [Wikipedia:Endoderm] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "entoderm" RELATED [] xref: AAO:0000139 ! endoderm xref: BILA:0000038 xref: BTO:0000800 xref: FBbt:00000125 ! endoderm xref: FMA:69071 ! Endoderm xref: GAID:1305 ! endoderm xref: MAT:0000175 ! endoderm xref: MIAA:0000175 ! endoderm xref: TAO:0000017 ! endoderm xref: XAO:0000090 ! endoderm xref: ZFA:0000017 ! endoderm xref: ncithesaurus:Endoderm ! Endoderm xref: EFO:0002545 ! endoderm xref: VHOG:0000154 ! embryonic endoderm xref: EHDAA2:0000436 ! endoderm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/df/Gray10.png/200px-Gray10.png xref: MESH:A16.254.425.407 ! endoderm xref: EV:0100005 ! endoderm is_a: UBERON:0000923 ! germ layer relationship: has_part CL:0000223 ! endodermal cell relationship: develops_from UBERON:0006595 {source="ZFA"} ! presumptive endoderm xref: SCTID:362855003 ! Entire endoderm xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png property_value: homology_notes "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000154", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) Limb development and evolution\, p.722", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "endodermal" xsd:string xref: UMLS:C0014144 [Term] id: UBERON:0000926 name: mesoderm alt_id: UBERON:0003263 def: "The middle germ layer of the embryo, between the endoderm and ectoderm." [Wikipedia:Mesoderm] comment: Taxon notes: sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates[UBERONREF:0000002] subset: uberon_slim subset: vertebrate_core synonym: "entire mesoderm" RELATED [UBERON:cjm, SCTID:362854004] synonym: "mesodermal mantle" RELATED [] xref: AAO:0000304 ! mesoderm xref: BILA:0000037 xref: BTO:0000839 xref: EMAPA:16083 ! mesoderm xref: EHDAA:124 ! mesoderm xref: EHDAA:160 ! mesoderm xref: EHDAA:168 ! mesoderm (also: UBERON:0003264 'mesoderm of yolk sac') xref: EHDAA:183 ! mesoderm xref: FBbt:00000126 ! mesoderm xref: FMA:69072 ! Mesoderm xref: GAID:522 ! mesoderm xref: MAT:0000174 ! mesoderm xref: MIAA:0000174 ! mesoderm xref: TAO:0000041 ! mesoderm xref: XAO:0000050 ! mesoderm xref: ZFA:0000041 ! mesoderm xref: ncithesaurus:Mesoderm ! Mesoderm xref: EFO:0001981 ! mesoderm xref: VHOG:0000152 ! embryonic mesoderm xref: EHDAA2:0001128 ! mesoderm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e8/Mesoderm.png/200px-Mesoderm.png xref: MESH:A16.254.425.660 ! mesoderm xref: EV:0100006 ! mesoderm is_a: UBERON:0000923 {notes="sometimes not considered primary"} ! germ layer relationship: has_part CL:0000222 ! mesodermal cell relationship: never_in_taxon NCBITaxon:6040 ! Porifera relationship: develops_from UBERON:0006603 {source="ZFA"} ! presumptive mesoderm xref: SCTID:362854004 ! Entire mesoderm xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png property_value: external_definition "Primary germ layer that is the middle of the embryonic germ layers.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000304", date_retrieved="2012-06-20", source="AAO:EJS"} synonym: "embryonic mesoderm" RELATED [VHOG:0000152] property_value: homology_notes "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000152", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) Limb development and evolution\, p.722", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "mesodermal" xsd:string xref: UMLS:C0025485 [Term] id: UBERON:0002342 name: neural crest def: "The neural crest, a transient component of the ectoderm, is located in between the neural tube and the epidermis (or the free margins of the neural folds) of an embryo during neural tube formation. Neural crest cells quickly migrate during or shortly after neurulation, an embryological event marked by neural tube closure." [Wikipedia:Neural_crest] comment: Editor note: consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). Taxon notes: A well developed neural crest population is present in lampreys (Horigome et al. 1999 ; Tomsa & Langeland, 1999) and gnathostomes. chordate fossils from the early Cambrian (Yunnanozoan and Haikouella) with apparent neural-crest derived structures (pharyngeal denticles and pharyngeal skeletons resembling the striped mucocartilage of the branchial bars in lamprey ammocoete larvae), suggests that neural crest arose very early in vertebrate evolution (Chen et al. 1999; Holland & Chen, 2001). The invertebrate chordates apparently lack defini- tive neural crest. One marker of migrating neural crest in some vertebrates, the antibody HNK1, does not recognize any cells in amphioxus embryos (Holland, unpublished). Even so, in both amphioxus and tunicates, cells at the edges of the neural plate and adjacent nonneural ectoderm share some properties of neural crest[PMID:11523831]. Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995), slug (Nieto et al., 1994), AP-2 (Zhang et al., 1996; Schorle et al., 1996), and Wnt-1/3a (Ikeya et al., 1997) are expressed in the dorsal most region of the neural tube, and have been shown to be involved in the generation of neural crest cells. subset: uberon_slim subset: vertebrate_core subset: vertebrate_core xref: FMA:86666 ! Neural crest xref: GAID:1310 ! neural crest xref: VHOG:0000057 ! neural crest xref: MAT:0000066 ! neural crest - early xref: MIAA:0000066 ! neural crest - early xref: TAO:0000045 ! neural crest (also: UBERON:0010170 'region of neural crest') xref: XAO:0000048 ! neural crest xref: ZFA:0000045 ! neural crest (also: UBERON:0010170 'region of neural crest') xref: ncithesaurus:Neural_Crest ! Neural Crest xref: BTO:0001764 ! neural crest xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Gray644.png/200px-Gray644.png xref: MESH:A16.254.600 ! neural crest is_a: UBERON:0010316 ! germ layer / neural crest relationship: part_of UBERON:0002346 {source="XAO", source="UBERONREF:0000002"} ! neural ectoderm relationship: develops_from UBERON:0003075 {source="BTO"} ! neural plate relationship: develops_from UBERON:0005062 {source="PMID:11523831"} ! neural fold relationship: only_in_taxon NCBITaxon:7711 {source="GOTAX:0000352"} ! Chordata relationship: only_in_taxon NCBITaxon:7742 {source="ISBN10:0073040584"} ! Vertebrata relationship: existence_starts_during UBERON:0000110 {source="PMID:11523831"} ! neurula stage relationship: composed_primarily_of CL:0000333 {notes="pre migratory UBERONREF:0000002"} ! neural crest cell xref: AAO:0010578 ! neural crest xref: SCTID:361462002 ! Neural crest xref: EHDAA2:0004419 ! neural crest synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] xref: http://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png property_value: external_definition "Migratory cell population which delaminates from neural tube, borders surface ectoderm and neural ectoderm, and gives rise to many different tissue types.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010578", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship type change: differentiates_from ectoderm (AAO:0000137) CHANGED TO: develops_from ectoderm (UBERON:0000924)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010578", date_retrieved="2012-06-20"} property_value: external_definition "A cell population arising from the dorsolateral aspect of the central nervous system primordium during the segmentation period, and later migrating along stereotyped pathways to give rise to a diverse and well-defined set of cell types including pigment cells, peripheral neurons and glia, and head cartilage. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000045", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "neural crest material" RELATED [VHOG:0000057] property_value: homology_notes "We conclude that the neural crest is a vertebrate novelty, but that neural crest cells and their derivatives evolved and diversified in a step-wise fashion - first by elaboration of neural plate border cells, then by the innovation or co-option of new or ancient metazoan cell fates.[well established][VHOG]" xsd:string {external_class="VHOG:0000057", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2012.01495.x Hall BK\, Gillis JA\, Incremental evolution of the neural crest\, neural crest cells and neural crest-derived skeletal tissues. J Anat (2012)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0027789 [Term] id: UBERON:0010170 name: region of neural crest is_a: UBERON:0000480 {source="EHDAA2"} ! anatomical group relationship: part_of UBERON:0002342 ! neural crest xref: ZFA:0000045 ! neural crest (also: UBERON:0002342 'neural crest') xref: TAO:0000045 ! neural crest (also: UBERON:0002342 'neural crest') property_value: external_definition "A cell population arising from the dorsolateral aspect of the central nervous system primordium during the segmentation period, and later migrating along stereotyped pathways to give rise to a diverse and well-defined set of cell types including pigment cells, peripheral neurons and glia, and head cartilage. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000045", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0000927 name: mesectoderm def: "A double row of cells which are located at the midline from the end of gastrulations. The morphology of these cells is distinct from adjacent ectodermal cells - they are elongated such that one end remains exposed to the outside of the embryo at the mideline while the other end bissects the internalised mesoderm." [FB:FBrf0089570] comment: Split term? The part of the mesenchyme derived from ectoderm, especially from the embryonic neural crest from which the pigment cells, meninges, and most of the branchial cartilages develop.[TFD] subset: uberon_slim synonym: "MesEc" RELATED [] xref: FBbt:00000136 ! mesectoderm xref: MAT:0000243 ! mesectoderm xref: MIAA:0000243 ! mesectoderm is_a: UBERON:0000923 ! germ layer relationship: adjacent_to UBERON:0000924 ! ectoderm property_value: has_relational_adjective "mesectodermal" xsd:string [Term] id: UBERON:0000928 name: embryonic segment comment: This class was created automatically from a combination of ontologies synonym: "segment - embryonic" EXACT [] xref: FBbt:00000154 ! embryonic segment xref: MAT:0000244 ! segment - embryonic xref: MIAA:0000244 ! segment - embryonic is_a: UBERON:0000914 ! organismal segment relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0000929 name: pharyngeal branch of vagus nerve def: "Motor nerve of the pharynx, arises from the upper part of the ganglion nodosum, and consists principally of filaments from the cranial portion of the accessory nerve." [Wikipedia:Pharyngeal_branch_of_vagus_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "pharyngeal branch of inferior vagal ganglion" EXACT [] synonym: "pharyngeal branch" EXACT [] synonym: "pharyngeal branch of vagus nerve" EXACT [] synonym: "ramus pharyngealis nervi vagalis" EXACT [] synonym: "tenth cranial nerve pharyngeal branch" EXACT [] synonym: "vagal pharyngeal branch" EXACT [] synonym: "vagus nerve pharyngeal branch" EXACT [] xref: FMA:6234 ! Pharyngeal branch of vagus nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5e/Gray791.png/200px-Gray791.png is_a: UBERON:0001021 ! nerve relationship: part_of UBERON:0001005 ! trachea relationship: part_of UBERON:0001759 ! vagus nerve synonym: "ramus pharyngeus" EXACT LATIN [FMA:TA, FMA:6234] xref: SCTID:280298006 ! Pharyngeal branch of vagus synonym: "ramus pharyngeus nervi vagi" RELATED LATIN [Wikipedia:Pharyngeal_branch_of_vagus_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png synonym: "pharyngeal branch of vagus" EXACT [FMA:6234] [Term] id: UBERON:0000932 name: obsolete ventral longitudinal muscle comment: originally unified on basis of terminological similarity consider: FBbt:00000482 ! ventral longitudinal muscle consider: WBbt:0005814 ! ventral longitudinal muscle is_obsolete: true [Term] id: UBERON:0000933 name: pharyngeal muscle def: "A muscle that acts on the pharynx[WP, vetted]." [Wikipedia:Pharyngeal_muscles, UBERON:cjm] comment: Innervation notes: They are innervated by the pharyngeal branch of the Vagus nerve (CN X) with the exception of the stylopharyngeus muscle which is innervated by the glossopharyngeal nerve (CN IX).[WP] property_value: external_definition "A pharyngeal muscle is any muscle that forms part of the pharynx[GO]." xsd:string {ontology="GO", external_class="GO:0043282", date_retrieved="2012-06-30", source="GOC:go_curators", notes="does not quite work for some muscles such as stylopharyngeus"} synonym: "branchial muscle" EXACT [ZFA:0000172] synonym: "muscle of pharynx" EXACT [] synonym: "pharynx muscle" EXACT [] synonym: "muscle organ of pharynx" EXACT [OBOL:automatic] synonym: "pharynx muscle organ" EXACT [OBOL:automatic] synonym: "musculus pharyngis" RELATED [BTO:0001048] xref: BTO:0001048 xref: FMA:46619 ! Muscle of pharynx xref: GAID:154 ! pharyngeal muscle xref: MA:0001797 ! pharynx muscle xref: ncithesaurus:Pharyngeal_Muscle ! Pharyngeal Muscle xref: MESH:A02.633.567.800 ! pharyngeal muscle xref: ZFA:0000172 ! branchial muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0004467 {source="ZFA"} ! musculature of pharynx xref: SCTID:244798004 ! Entire pharyngeal muscle xref: TAO:0000172 ! branchial muscle synonym: "musculi pharyngis" RELATED LATIN [Wikipedia:Pharyngeal_muscles] synonym: "tunica muscularis pharyngis" RELATED LATIN [Wikipedia:Pharyngeal_muscles] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Gray1030.png synonym: "branchial muscles" RELATED PLURAL [TAO:0000172] xref: EFO:0003504 ! branchial muscle xref: UMLS:C0031346 [Term] id: UBERON:0004467 name: musculature of pharynx def: "A musculature that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] comment: See comments for 'pharyngeal muscle' subset: vertebrate_core xref: FMA:264609 ! Musculature of pharynx xref: ZFA:0001307 ! pharyngeal musculature is_a: UBERON:0001015 ! musculature relationship: overlaps UBERON:0001042 ! chordate pharynx xref: TAO:0001307 ! pharyngeal musculature synonym: "set of muscles of pharynx" RELATED [FMA:264609] synonym: "pharyngeal musculature" EXACT [TAO:0001307] [Term] id: UBERON:0011996 ! pharyngeal adductor name: pharyngeal adductor is_a: UBERON:0000933 {source="ZFA"} ! pharyngeal muscle xref: TAO:0000463 ! adductor xref: ZFA:0000463 ! adductor [Term] id: UBERON:0010937 name: salpingopharyngeus muscle def: "The salpingopharyngeus muscle arises from the inferior part of the cartilage of the pharyngotympanic tube (Eustachian tube) in the nasal cavity; it passes downward and blends with the posterior fasciculus of the palatopharyngeus muscle. The salpingopharyngeus is known to raise the pharynx and larynx during deglutition (swallowing) and laterally draws the pharyngeal walls up. In addition, it opens the pharyngeal orifice of the pharyngotympanic tube during swallowing. This allows for the equalization of pressure between the auditory canal and the pharynx. The salpingopharyngeus is innervated by the vagus nerve (CN X) via the pharyngeal plexus." [Wikipedia:Salpingopharyngeus_muscle] synonym: "salpingopharyngeus" EXACT [Wikipedia:Salpingopharyngeus_muscle] is_a: UBERON:0000933 {source="FMA"} ! pharyngeal muscle xref: FMA:46665 ! salpingopharyngeus xref: ncithesaurus:Salpingopharyngeus ! salpingopharyngeus synonym: "musculus salpingopharyngeus" RELATED LATIN [Wikipedia:Salpingopharyngeus_muscle] relationship: has_muscle_insertion UBERON:0010234 {source="dbpedia", notes="fibers pass downward and blend with the palatopharyngeus muscle to the upper border thyroid cartilage blending with constrictor fibers"} ! palatopharyngeus relationship: has_muscle_insertion UBERON:0001738 {source="dbpedia", notes="fibers pass downward and blend with the palatopharyngeus muscle to the upper border thyroid cartilage blending with constrictor fibers"} ! thyroid cartilage relationship: innervated_by UBERON:0001759 {source="dbpedia", notes="vagus nerve and cranial accessory nerve"} ! vagus nerve relationship: innervated_by UBERON:0002019 {source="dbpedia", notes="vagus nerve and cranial accessory nerve"} ! accessory XI nerve relationship: has_muscle_origin UBERON:0007354 {source="dbpedia", notes="lower part of the cartilage of the auditory tube"} ! cartilage of pharyngotympanic tube xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Salpingopharyngeus.png property_value: external_definition "Salpingopharyngeus is a muscle that attaches to pharyngotympanic tube and the pharynx and is innervated by pharyngeal plexus of CN X and participates in oral/pharyngeal behaviors.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: SCTID:244807009 ! Entire salpingopharyngeus muscle relationship: in_lateral_side_of UBERON:0001042 {source="FMA-abduced-lr"} ! chordate pharynx xref: UMLS:C1521985 [Term] id: UBERON:0002240 name: spinal cord def: "Elongated, approximately cylindrical part of the central nervous system that lies in the vertebral canal and from which the spinal nerves emerge." [OMD:spinal+cord, Wikipedia:Spinal_cord] comment: TODO: add superclass to unify with VNC? subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "spinal cord structure" RELATED [ZFA:0000075] synonym: "medulla spinalis" RELATED [BTO:0001279] synonym: "spinal medulla" RELATED [BTO:0001279] xref: BTO:0001279 xref: EFO:0000110 ! spinal cord xref: EHDAA:2863 ! spinal cord xref: FMA:7647 ! Spinal cord xref: GAID:695 ! spinal cord xref: VHOG:0000601 ! spinal cord xref: MA:0000216 ! spinal cord xref: MAT:0000183 ! spinal cord xref: MIAA:0000183 ! spinal cord xref: NIF_GrossAnatomy:birnlex_1709 ! Spinal cord xref: OpenCyc:Mx4rvVjjk5wpEbGdrcN5Y29ycA xref: TAO:0000075 ! spinal cord xref: XAO:0000020 ! spinal cord xref: ZFA:0000075 ! spinal cord xref: ncithesaurus:Spinal_Cord ! Spinal Cord xref: OpenCyc:Mx4rvVjjk5wpEbGdrcN5Y29ycA ! spinal cord xref: EHDAA2:0001255 ! spinal cord xref: EMAPA:17577 ! spinal cord of central nervous system of nervous system of organ system xref: EMAPA:17700 ! spinal cord of central nervous system of nervous system of tail of embryo xref: MESH:A08.186.854 ! spinal cord xref: EV:0100316 ! spinal cord xref: BM:SpC ! spinal cord is_a: UBERON:0000489 ! cavitated compound organ relationship: develops_from UBERON:0003076 ! posterior neural tube relationship: spatially_disjoint_from UBERON:0000955 ! brain relationship: part_of UBERON:0001017 ! central nervous system relationship: part_of UBERON:0001137 ! dorsum relationship: has_part CL:0005000 {source="ZFA"} ! spinal cord interneuron xref: AAO:0010151 ! spinal cord xref: SCTID:180959008 ! Entire spinal cord subset: organ_slim relationship: immediate_transformation_of UBERON:0006241 {evidence="definitional"} ! future spinal cord relationship: has_developmental_contribution_from UBERON:0003853 {evidence="definitional"} ! spinal cord neural crest synonym: "medulla spinalis" RELATED LATIN [Wikipedia:Spinal_cord] xref: http://upload.wikimedia.org/wikipedia/commons/5/58/Spinal_cord_direv.svg property_value: external_definition "Part of the central nervous system which descends from the hindbrain within the vertebral column.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010151", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000601", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.165", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0037925 [Term] id: UBERON:0005053 ! nerve cord name: nerve cord subset: dubious_grouping xref: BILA:0000136 ! nerve cord xref: BTO:0001656 ! nerve cord is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0005054 name: dorsal nerve cord def: "The dorsal tubular cord of nervous tissue above the notochord of a chordate that comprises or develops into the central nervous system[BTO]. The nerve cord of chordates develops dorsally in the body as a hollow tube above the notochord. In most species it differentiates in embryogeny into the brain anteriorly and spinal cord that runs through the trunk and tail. Together the brain and spinal cord are the central nervous system to which peripheral sensory and motor nerves connect[TOL]. The dorsal nerve cord is one of the embryonic features unique to chordates, along with a notochord, a post-anal tail and pharyngeal slits. The dorsal nerve cord is a hollow cord dorsal to the notochord. It is formed from a part of the ectoderm that rolls, forming the hollow tube, compared to other animal phyla, which have solid, ventral tubes. The dorsal nerve cord is later modified into the brain and spinal cord. Dorsal nerve cord is mainly found in phylum Vertebrata[WP]." [BTO:0002329, Wikipedia:Dorsal_nerve_cord, http://tolweb.org/Chordata/2499] xref: BTO:0002329 ! dorsal nerve cord is_a: UBERON:0005053 ! nerve cord relationship: develops_from UBERON:0000924 ! ectoderm relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata [Term] id: UBERON:0000934 name: ventral nerve cord def: "The pair of closely united ventral longitudinal nerves with their segmental ganglia that is characteristic of many elongate invertebrates (as earthworms)[BTO]. A large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring[WB]. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms[GO]." [WB:Paper00000938, Wikipedia:Ventral_nerve_cord, GO:0007419, BTO:0002328] comment: The ventral nerve cords make up the nervous system of some phyla of the invertebrates, particularly within the nematodes, annelids and the arthropods. It usually consists of cerebral ganglia anteriorly with the nerve cords running down the ventral ('belly', as opposed to back) plane of the organism. This characteristic is important in qualifying the difference compared to the chordates, which have a dorsal nerve cord. Ventral nerve cords from anterior to posterior (the thoracic and abdominal tagma in the arthropods) are made up of segmented ganglia that are connected by a tract of nerve fibers passing from one side to the other of the nerve cord called commissures. The complete system bears some likeness to a rope ladder. In some animals the bilateral ganglia are fused into a single large ganglion per segment. This characteristic is found mostly in the insects. subset: uberon_slim synonym: "ventral cord" EXACT [GO:0007419] xref: EFO:0000896 ! ventral nerve cord xref: FBbt:00001102 ! ventral nerve cord xref: MAT:0000339 ! ventral nerve cord xref: MIAA:0000339 ! ventral nerve cord xref: WBbt:0005829 ! ventral nerve cord xref: BTO:0002328 ! ventral nerve cord is_a: UBERON:0005053 ! nerve cord relationship: never_in_taxon NCBITaxon:7711 ! Chordata [Term] id: UBERON:0000937 name: obsolete proneural cluster synonym: "proneural clusters" RELATED [ZFA:0000068] consider: FBbt:00001135 ! proneural cluster consider: ZFA:0000068 ! proneural cluster is_obsolete: true comment: obsoleted because inconsistencies arise due to ZFA term being both embryonic and extraembryonic [Term] id: UBERON:0000939 name: imaginal disc def: "A tissue in the larva which gives rise to the adult external cuticle." [FB:gg, Wikipedia:Imaginal_disc] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "imaginal disk" RELATED [] xref: FBbt:00001761 ! imaginal disc xref: MAT:0000064 ! imaginal disc xref: MIAA:0000064 ! imaginal disc xref: BTO:0004658 ! imaginal disc is_a: UBERON:0000481 ! multi-tissue structure relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0001908 name: optic tract def: "Diencephalic white matter (tract) which is comprised of retinal ganglion cell axons after which they have passed through the optic chiasm[ZFA]. Predominantly white matter structure found in diencephalon consisting of fibers originating in the retina. The optic tract is considered to extend from the point of the optic chiasm and terminates largely, although not exclusively, in the lateral geniculate complex. Other fibers end in the superior colliculus and other structures in the diencephalon, midbrain and brainstem (MM)[NIF]." [Wikipedia:Optic_tract, ZFIN:curator, NIF_GrossAnatomy] comment: editor note: relationships need checking by expert. NIF and ZFA both state part of diencepahalon; MA says part of optic nerve II. in uberon, CNS and PNS are spatially disjoint, and axon tracts are part of the CNS so we make the relationship to CNII 'continuous_with' subset: uberon_slim subset: vertebrate_core synonym: "optic lemniscus" EXACT [] synonym: "visual pathway" RELATED [GAID:735] xref: FMA:62046 ! Optic tract xref: VHOG:0001164 ! optic tract xref: MA:0001099 ! optic tract xref: NIF_GrossAnatomy:birnlex_1684 ! Optic tract xref: TAO:0000252 ! optic tract xref: ZFA:0000252 ! optic tract xref: MESH:A08.612.220.860 ! visual pathway xref: GAID:735 ! visual pathway xref: ncithesaurus:Optic_Tract ! Optic Tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Gray773.png/200px-Gray773.png xref: BM:Tel-OT ! optic tract is_a: UBERON:0001018 ! axon tract relationship: continuous_with UBERON:0000959 ! optic chiasma relationship: part_of UBERON:0001894 ! diencephalon relationship: continuous_with UBERON:0000941 ! cranial nerve II relationship: part_of UBERON:0002104 ! visual system xref: SCTID:280952003 ! Entire optic tract xref: XAO:0004101 ! optic tract synonym: "tractus opticus" RELATED LATIN [Wikipedia:Optic_tract] xref: http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray773.png xref: UMLS:C0152405 [Term] id: UBERON:0000959 name: optic chiasma def: "Nerve trunk which is continuous with right and left optic nerves and right and left optic tracts.[FMA]" [Wikipedia:Optic_chiasm, ZFIN:curator, FMA:FMA] subset: uberon_slim subset: vertebrate_core synonym: "decussation of optic nerve fibers" EXACT [] synonym: "optic chiasm" EXACT [Wikipedia:Optic_chiasm] synonym: "chiasma opticum" EXACT LATIN [Wikipedia:Optic_chiasm] xref: EHDAA:10227 ! optic chiasm xref: FMA:62045 ! Optic chiasm xref: GAID:832 ! optic chiasm xref: VHOG:0000190 ! optic chiasm xref: MA:0001098 ! optic chiasm xref: NIF_GrossAnatomy:birnlex_1416 ! Optic chiasm xref: TAO:0000556 ! optic chiasm xref: ZFA:0000556 ! optic chiasm xref: EHDAA2:0001302 ! optic chiasm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/1543%2CVisalius%27OpticChiasma.jpg/200px-1543%2CVisalius%27OpticChiasma.jpg xref: EMAPA:17603 ! optic chiasma xref: MESH:A08.800.800.120.680.600 ! optic chiasm xref: BM:Tel-OCX ! optic chiasm is_a: UBERON:0002464 ! nerve trunk relationship: continuous_with UBERON:0000941 ! cranial nerve II relationship: part_of UBERON:0001894 ! diencephalon synonym: "chiasma opticum" EXACT LATIN [FMA:TA, FMA:62045] xref: AAO:0010622 ! optic chiasm xref: SCTID:244453006 ! Optic chiasma xref: XAO:0004071 ! optic chiasm xref: ncithesaurus:Optic_Chiasm ! optic chiasm property_value: external_definition "The point at which fibers of the optic nerves cross.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010622", date_retrieved="2012-06-20", source="AAO:DSM"} property_value: homology_notes "The chiasm has been studied in great detail in some animals, while in others relatively little or nothing is known. Although there are some gross architectural features that are conserved within some animals, such as birds and fish, the general picture is one of diversity. This review will attempt to consider the key features of such diversity of chiasmatic organisation in vertebrates and the mechanisms that sculpt them from the limited literature that is available. However, as so much research has been undertaken on the structure and development of the chiasm in laboratory animals, any review must consider the information that has been gleaned from them and hope that future studies will determine whether the features revealed in these animals, and the underlying mechanisms that generate them, have a common vertebrate plan.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000190", ontology="VHOG", source="DOI:10.1016/j.preteyeres.2005.04.005 Jeffery G\, Erskine L\, Variations in the architecture and development of the vertebrate optic chiasm. Progress in retinal and eye research (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0029126 [Term] id: UBERON:0004904 name: nerve connecting eye with brain def: "A nerve that connects the eye to the brain and carries the impulses formed by the retina to the visual cortex of the brain[BTO]." [BTO:0000966] comment: for the vertebrate-specific structure, see UBERON:0000941 (cranial nerve II) subset: grouping_class synonym: "optic nerve (generic)" EXACT [] synonym: "optic nerve" BROAD [BTO:0000966] xref: BTO:0000966 ! optic nerve xref: FBbt:00001956 ! optic nerve xref: TADS:0000232 ! adult optic nerve xref: EV:0100351 ! optic nerve intersection_of: UBERON:0001021 ! nerve intersection_of: continuous_with UBERON:0005388 ! photoreceptor array intersection_of: continuous_with UBERON:0000955 ! brain relationship: part_of UBERON:0002104 ! visual system [Term] id: UBERON:0000941 name: cranial nerve II def: "Cranial nerve which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]." [ISBN:0471209627, Wikipedia:Optic_nerve, ZFA:0000435] comment: Editor notes: A sensory tract that develops as an outpocketing of the brain - we classify as a cranial nerve as is traditional, but not strictly a nerve. AO notes: (relaion to eye): MA, XAO, AAO and BTO consider this part of the eye. This is in contrast to GO, FMA, EHDAA2 (FMA has a class 'intra-ocular part of optic nerve' which represents the region of overlap). Relation to brain: part of diencephalon in EHDAA2, ZFA. In NIF, has the optic nerve root as part, which is a feature part of the diencphalon. Structure notes: We are consistent here with the FMA in considering CN-II continuous with the retina. Editor notes: - determine the precise relationship between CN II and the CNS subset: uberon_slim subset: vertebrate_core synonym: "CN-II" RELATED [ZFA:0000435] synonym: "optic nerve" BROAD SENSU [FMA:50863, ZFA:0000435] synonym: "optic II nerve" EXACT [EHDAA2:0001313] synonym: "optic nerve [II]" EXACT [] synonym: "second cranial nerve" EXACT [] synonym: "optic II" EXACT [EHDAA2:0001313] synonym: "cranial II" EXACT [] synonym: "nervus opticus [II]" EXACT LATIN [FMA:TA, FMA:50863] synonym: "nervus opticus" EXACT [] synonym: "02 optic nerve" EXACT [AAO:0010345] xref: EHDAA:6788 ! optic nerve xref: FMA:50863 ! Optic nerve xref: GAID:831 ! optic nerve xref: VHOG:0000543 ! optic nerve xref: MA:0001097 ! optic II nerve xref: NIF_GrossAnatomy:birnlex_1640 ! Optic nerve xref: OpenCyc:Mx4rvVjLm5wpEbGdrcN5Y29ycA xref: TAO:0000435 ! cranial nerve II xref: XAO:0000188 ! cranial nerve II xref: ZFA:0000435 ! cranial nerve II xref: ncithesaurus:Optic_Nerve ! Optic Nerve xref: OpenCyc:Mx4rvVjLm5wpEbGdrcN5Y29ycA ! optic nerve xref: EHDAA2:0001313 ! optic II nerve xref: EMAPA:17846 ! optic nerve xref: EMAPA:17575 ! optic II xref: MESH:A08.800.800.120.680 ! optic nerve xref: AAO:0010345 ! 02 optic nerve xref: SCTID:180938001 ! Entire optic nerve is_a: UBERON:0002464 ! nerve trunk intersection_of: UBERON:0001785 ! cranial nerve intersection_of: continuous_with UBERON:0000966 ! retina intersection_of: continuous_with UBERON:0000959 ! optic chiasma relationship: develops_from UBERON:0003902 {source="EHDAA2"} ! retinal neural layer relationship: continuous_with UBERON:0003098 ! optic stalk relationship: part_of UBERON:0002104 ! visual system property_value: external_definition "Fibrous, somatic sensory element covered by a fibrous connective-tissue sheath and is continuous with the layer of nerve cells on the inner surface of the eye.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010345", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "A collection of nerve cells that project visual information from the eyes to the brain. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000435", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "optic" RELATED [TAO:0000435] property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup (reference 1); The (optic) stalk persists as the optic nerve (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000543", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429\, http://medical-dictionary.thefreedictionary.com/optic+stalk", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: EFO:0004258 ! optic nerve xref: UMLS:C0029130 [Term] id: UBERON:0000942 name: frontal nerve (branch of ophthalmic) def: "The frontal nerve is the largest branch of the ophthalmic, and may be regarded, both from its size and direction, as the continuation of the nerve. It enters the orbit through the supraorbital foramen, and runs forward between the Levator palpebræ superioris and the periosteum. Midway between the apex and base of the orbit it divides into two branches, supratrochlear nerve and supraorbital nerve. [WP,unvetted]." [Wikipedia:Frontal_nerve] subset: uberon_slim synonym: "frontal nerve" EXACT [FMA:52638] xref: FMA:52638 ! frontal nerve xref: ncithesaurus:Frontal_Nerve ! Frontal Nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/45/Gray787.png/200px-Gray787.png is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0000348 {source="FMA"} ! ophthalmic nerve xref: SCTID:280219004 ! Entire frontal nerve synonym: "nervus frontalis" RELATED LATIN [Wikipedia:Frontal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/4/45/Gray787.png xref: UMLS:C0228712 [Term] id: UBERON:0000943 name: obsolete labial sensillum consider: FBbt:00002721 ! labial sensillum consider: WBbt:0005107 ! labial sensillum is_obsolete: true [Term] id: UBERON:0000944 name: obsolete dorsal branch synonym: "dorsal vein" EXACT [] consider: FBbt:00003051 ! dorsal branch consider: FMA:76733 ! Dorsal vein is_obsolete: true synonym: "ramus dorsalis" EXACT LATIN [FMA:TA, FMA:76733] [Term] id: UBERON:0000946 name: cardial valve def: "Flap of tissue that prevents regurgitation of blood from the ventricles to the atria or from the pulmonary arteries or aorta to the ventricles." [Wikipedia:Cardiac_valve] comment: Terminology notes: Rector et al: One might be tempted to define “heart valve” equivalently to “valve in the heart”, and “valve” as a “structure which functions as a valve”. But this combination results in the “foramen ovale” being classified as a kind of “heart valve”, since it is undoubtedly located in the heart and functions as a valve subset: uberon_slim subset: vertebrate_core synonym: "cardiac valve" RELATED [GO:0003170] synonym: "heart valve" EXACT [] synonym: "heart valves" RELATED [] synonym: "stomodaeal valve" RELATED [] synonym: "valve of heart" EXACT [] xref: BTO:0000564 xref: FMA:7110 ! Cardiac valve xref: GAID:176 ! heart valve xref: galen:HeartValve xref: VHOG:0000818 ! heart valve xref: MA:0000086 ! heart valve xref: OpenCyc:Mx4rv8oyuJwpEbGdrcN5Y29ycA xref: TAO:0005065 ! heart valve xref: ZFA:0005065 ! heart valve xref: ncithesaurus:Cardiac_Valve ! Cardiac Valve xref: OpenCyc:Mx4rv8oyuJwpEbGdrcN5Y29ycA ! heart valve xref: MESH:A07.541.510 ! heart valve xref: EMAPA:17869 ! valve of heart xref: EV:0100024 ! cardiac valve is_a: UBERON:0003978 ! valve relationship: part_of UBERON:0000948 ! heart relationship: develops_from UBERON:0002062 {source="PMID:15797462"} ! endocardial cushion disjoint_from: UBERON:0004754 ! foramen ovale of heart xref: SCTID:181285005 ! Entire heart valve xref: XAO:0004126 ! cardiac valve property_value: external_definition "One of the four structures within the heart that prevent backflow of blood by opening and closing with each heartbeat. The valves include two semilunar valves, the aortic and pulmonary; the mitral or bicuspid valve; and the tricuspid valve. The valves permit blood flow in only one direction. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000818", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/heart+valve", source="http://bgee.unil.ch/"} property_value: homology_notes "Extensive conservation of valve developmental mechanisms also has been observed among vertebrate species including chicken, mouse, and human.[well established][VHOG]" xsd:string {external_class="VHOG:0000818", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0018826 [Term] id: UBERON:0010191 name: aortic system is_a: UBERON:0000480 {source="EHDAA2"} ! anatomical group xref: EHDAA2:0004512 ! aortic system [Term] id: UBERON:0000947 name: aorta def: "Artery carrying blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation" [Wikipedia:Aorta] comment: Editor notes: This class is currently a mixed bag, encompassing (1) the entirety of the mammalian aorta together with (2) the developmental and phylogenetic homologs of its segments: the ventral aorta and dorsal aortae. Taxon notes: All amniotes have a broadly similar arrangement to that of humans, albeit with a number of individual variations. In fish, however, there are two separate vessels referred to as aortas. The ventral aorta carries de-oxygenated blood from the heart to the gills; part of this vessel forms the ascending aorta in tetrapods (the remainder forms the pulmonary artery). A second, dorsal aorta carries oxygenated blood from the gills to the rest of the body, and is homologous with the descending aorta of tetrapods. The two aortas are connected by a number of vessels, one passing through each of the gills. Amphibians also retain the fifth connecting vessel, so that the aorta has two parallel arches[WP]. subset: uberon_slim subset: grouping_class synonym: "dorsal aorta" NARROW SENSU [ZFA:0000014, Wikipedia:Aorta#In_other_animals] synonym: "trunk of aortic tree" EXACT [] synonym: "trunk of systemic arterial tree" EXACT [] xref: BTO:0000135 xref: EFO:0000265 ! aorta xref: FMA:3734 ! Aorta xref: GAID:469 ! aorta xref: galen:Aorta xref: VHOG:0001523 ! aorta xref: MA:0000062 ! aorta xref: MAT:0000035 ! aorta xref: MIAA:0000035 ! aorta xref: OpenCyc:Mx4rvVjvTpwpEbGdrcN5Y29ycA xref: XAO:0003010 ! aorta xref: ncithesaurus:Aorta ! Aorta xref: OpenCyc:Mx4rvVjvTpwpEbGdrcN5Y29ycA ! aorta xref: MESH:A07.231.114.056 ! aorta xref: EMAPA:18601 ! aorta xref: EV:0100027 ! aorta is_a: UBERON:0001637 {source="BTO"} ! artery is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel relationship: overlaps UBERON:0002224 {source="MA-modified"} ! thoracic cavity relationship: part_of UBERON:0004571 {source="Wikipedia"} ! systemic arterial system relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system xref: AAO:0010213 ! aorta xref: SCTID:181298001 ! Entire aorta synonym: "aorta, arteria maxima" RELATED LATIN [Wikipedia:Aorta] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Aorta_scheme.jpg property_value: external_definition "The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010213", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {external_class="VHOG:0001523", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "aortic" xsd:string xref: UMLS:C0003483 [Term] id: UBERON:0005805 ! dorsal aorta name: dorsal aorta def: "The artery in vertebrate embryos that transports blood from the aortic arches to the trunk and limbs. In adult fish it is a major artery that carries oxygenated blood from the efferent branchial arteries to branches that supply the body organ. In adult tetrapods it arises from the systemic arch[BTO]. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once[GO]. Each primitive aorta receives anteriorly a vein 'the vitelline vein' from the yolk-sac, and is prolonged backward on the lateral aspect of the notochord under the name of the dorsal aorta. The dorsal aortae give branches to the yolk-sac, and are continued backward through the body-stalk as the umbilical arteries to the villi of the chorion. The two dorsal aortae combine to become the descending aorta in later development[WP]." [Wikipedia:Dorsal_aorta, GO:0035907, https://sourceforge.net/tracker/?func=detail&aid=3316981&group_id=36855&atid=440764, BTO:0004673] subset: vertebrate_core synonym: "dorsal aort%c3%a6" RELATED [Wikipedia:Dorsal_aorta] synonym: "dorsal aorta root" RELATED [VHOG:0000264] synonym: "dorsal aortic root" RELATED [VHOG:0000264] synonym: "DA" EXACT [ZFA:0000014] xref: VHOG:0000264 ! dorsal aorta xref: ZFA:0000014 ! dorsal aorta xref: VHOG:0000264 ! dorsal aorta xref: EHDAA:402 ! dorsal aorta xref: XAO:0000051 ! dorsal aorta xref: BTO:0004673 ! dorsal aorta xref: EMAPA:18606 ! dorsal aorta of aorta is_a: UBERON:0000947 ! aorta relationship: develops_from UBERON:0003064 ! intermediate mesoderm relationship: develops_from UBERON:0001917 ! endothelium of artery relationship: part_of UBERON:0002201 ! vasculature of trunk relationship: homologous_to UBERON:0001514 {source="Wikipedia"} ! descending aorta xref: AAO:0011029 ! dorsal aorta xref: SCTID:338637006 ! Entire dorsal aorta xref: TAO:0000014 ! dorsal aorta synonym: "aortae dorsales" RELATED LATIN [Wikipedia:Dorsal_aorta] xref: http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray459.png property_value: external_definition "Principal unpaired, median artery of the trunk, leading from the paired roots (radices) of the dorsal aorta to the caudal artery. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000014", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of axial vasculature (TAO:0001073)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000014", date_retrieved="2012-08-14"} property_value: homology_notes "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {external_class="VHOG:0000264", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0010190 name: pair of dorsal aortae synonym: "paired dorsal aortae" EXACT [EHDAA2:0000410] is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system xref: EHDAA2:0000410 ! paired dorsal aortae xref: MA:0000476 ! dorsal aorta [Term] id: UBERON:0005613 name: left dorsal aorta comment: Contributes to the arch of aorta in humans[http://emedicine.medscape.com/article/899609-overview] xref: MA:0000478 ! left dorsal aorta xref: EHDAA2:0000936 ! left dorsal aorta xref: EMAPA:16205 ! left of dorsal aorta of arterial system of cardiovascular system of organ system xref: VHOG:0000484 ! left dorsal aorta xref: EHDAA:404 ! left of dorsal aorta xref: SCTID:361403005 ! Primitive left dorsal aorta is_a: UBERON:0000947 ! aorta relationship: part_of UBERON:0005805 ! dorsal aorta property_value: homology_notes "A study of embryos shows that in all vertebrates six arterial arches link the ventral aorta with a pair of lateral dorsal aortae on each side of the body. The latter unite posteriorly to form a single median dorsal aorta wich takes blood to the body.[well established][VHOG]" xsd:string {external_class="VHOG:0000484", ontology="VHOG", source="ISBN:978-0174480198 Roberts MBV\, Biology: a functional approach (1986) p.572", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005622 name: right dorsal aorta comment: Normally regresses in humans[http://emedicine.medscape.com/article/899609-overview] xref: MA:0000479 ! right dorsal aorta xref: EHDAA2:0001720 ! right dorsal aorta xref: EMAPA:16206 ! right of dorsal aorta of arterial system of cardiovascular system of organ system xref: VHOG:0000485 ! right dorsal aorta xref: EHDAA:406 ! right of dorsal aorta xref: SCTID:361404004 ! Primitive right dorsal aorta is_a: UBERON:0000947 ! aorta relationship: part_of UBERON:0005805 ! dorsal aorta property_value: homology_notes "A study of embryos shows that in all vertebrates six arterial arches link the ventral aorta with a pair of lateral dorsal aortae on each side of the body. The latter unite posteriorly to form a single median dorsal aorta wich takes blood to the body.[well established][VHOG]" xsd:string {external_class="VHOG:0000485", ontology="VHOG", source="ISBN:978-0174480198 Roberts MBV\, Biology: a functional approach (1986) p.572", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003085 name: ventral aorta def: "The artery in vertebrate embryos that carries blood from the ventricle of the heart to the aortic arches. In adult fish it branches into afferent branchial arteries supplying the gills. In adult tetrapods it is represented by the ascending part of the aorta[BTO]. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once[GO]." [BTO:0004674, GO:0035908] comment: Taxon notes (via vHOG): "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them." Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective, Third Edition (2001) Orlando Fla.: Harcourt College Publishers, p.620. // in Reptiles, splits to form bases of 3 arteries: left aortic arch, right aortic arch and pulmonary trunk. In birds, the right systemic arch becomes predominant, the left never fully develops [Kardong] subset: uberon_slim xref: VHOG:0000121 ! ventral aorta xref: TAO:0000604 ! ventral aorta xref: XAO:0000338 ! ventral aorta xref: ZFA:0000604 ! ventral aorta xref: BTO:0004674 ! ventral aorta is_a: UBERON:0000947 ! aorta relationship: homologous_to UBERON:0001496 {source="Wikipedia", source="PMID:2297080"} ! ascending aorta relationship: channels_from UBERON:0000948 ! heart xref: AAO:0010412 ! ventral aorta property_value: external_definition "Outflow artery from the heart to the aortic arches. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000604", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {external_class="VHOG:0000121", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001496 ! ascending aorta name: ascending aorta def: "The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart’s axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]" [Wikipedia:Ascending_aorta, GO:0035905] subset: uberon_slim synonym: "pars ascendens aortae" EXACT [] xref: FMA:3736 ! Ascending aorta xref: MA:0002570 ! ascending aorta xref: ncithesaurus:Ascending_Aorta ! Ascending Aorta xref: EHDAA:9828 ! ascending aorta xref: OpenCyc:Mx4rwVFqO5wpEbGdrcN5Y29ycA ! ascending aorta xref: EHDAA2:0000147 ! ascending aorta xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Gray506.svg/200px-Gray506.svg.png xref: EMAPA:17014 ! ascending aorta of aortico-pulmonary spiral septum xref: EMAPA:18604 ! ascending xref: EMAPA:25959 ! ascending aorta of arterial system of cardiovascular system of organ system is_a: UBERON:0005800 ! segment of aorta relationship: part_of UBERON:0001515 ! thoracic aorta relationship: develops_from UBERON:0005338 {source="EHDAA2"} ! outflow tract aortic component relationship: has_developmental_contribution_from UBERON:0002061 ! truncus arteriosus relationship: has_developmental_contribution_from UBERON:0005432 ! aortic sac xref: SCTID:181299009 ! Entire ascending aorta synonym: "pars ascendens aortae, aorta ascendens" RELATED LATIN [Wikipedia:Ascending_aorta] xref: http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg xref: UMLS:C0003956 [Term] id: UBERON:0000949 name: endocrine system def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [NLM:endocrine+system, Wikipedia:Endocrine_system] subset: uberon_slim subset: vertebrate_core synonym: "endocrine system" EXACT [] synonym: "systema endocrinum" EXACT [] synonym: "endocrine glandular system" EXACT [EHDAA2:0002224] xref: FBbt:00005068 ! endocrine system xref: FMA:9668 ! Endocrine system xref: GAID:439 ! endocrine system xref: VHOG:0000098 ! endocrine system xref: MA:0000012 ! endocrine system xref: TAO:0001158 ! endocrine system xref: XAO:0000158 ! endocrine system xref: ZFA:0001158 ! endocrine system xref: ncithesaurus:Endocrine_System ! Endocrine System xref: MESH:A06 ! endocrine system xref: EV:0100128 ! endocrine system xref: EFO:0002969 ! endocrine system xref: EHDAA2:0002224 ! endocrine glandular system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0050886 ! endocrine process disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system xref: AAO:0010279 ! endocrine system xref: SCTID:278876000 ! Entire endocrine system property_value: external_definition "Anatomical system containing glands which regulates bodily functions though the secretion of hormones.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010279", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "Multicellular organisms have complex endocrine systems, allowing responses to environmental stimuli, regulation of development, reproduction, and homeostasis. Nuclear receptors (NRs), a metazoan-specific family of ligand-activated transcription factors, play central roles in endocrine responses, as intermediates between signaling molecules and target genes. The NR family includes ligand-bound and orphan receptors, that is, receptors with no known ligand or for which there is no ligand Pocket. Understanding NR evolution has been further improved by comparison of several completed genomes, particularly those of deuterostomes and ecdysozoans. In contrast, evolution of NR ligands is still much debated. One hypothesis proposes that several independent gains and losses of ligand-binding ability in NRs occurred in protostomes and deuterostomes. A second hypothesis, pertaining to the NR3 subfamily (vertebrate steroid hormone receptors and estrogen related receptor), proposes that before the divergence of protostomes and deuterostomes, there was an ancestral steroid receptor (AncSR) that was ligand-activated and that orphan receptors secondarily lost the ability to bind a ligand. (...) Our analysis reveals that steroidogenesis has been independently elaborated in the 3 main bilaterian lineages (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000098", ontology="VHOG", source="DOI:10.1073/pnas.0812138106 Markov GV\, Tavares R\, Dauphin-Villemant C\, Demeneix BA\, Baker ME\, Laudet V\, Independent elaboration of steroid hormone signaling pathways in metazoans. PNAS (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "endocrine" xsd:string xref: UMLS:C0014136 [Term] id: UBERON:0000951 name: rotator muscle of the vertebral column def: "Any of a number of short transversospinal muscles chiefly developed in cervical, lumbar, and thoracic regions, arising from the transverse process of one vertebra and inserted into the root of the spinous process of the next two or three vertebrae above, with nerve supply from the dorsal branches of the spinal nerve, and whose actions rotate the vertebral column." [http://medical-dictionary.thefreedictionary.com/rotator+muscle] comment: This class was created automatically from a combination of ontologies synonym: "rotator muscle" EXACT [FMA:23081] xref: FMA:23081 ! rotator muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0001137 ! dorsum relationship: attaches_to UBERON:0002412 ! vertebra xref: SCTID:244872002 ! Entire rotator muscle [Term] id: UBERON:0000954 name: obsolete intestine muscle def: "intestinal muscle cell, attach to intestine and body wall anterior to anus" [WB:Paper00000653] subset: uberon_slim synonym: "intestinal muscle" EXACT [] consider: FBbt:00003537 ! intestine muscle consider: WBbt:0005796 ! intestinal muscle is_obsolete: true [Term] id: UBERON:0000955 name: brain def: "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals.[1] Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." [Wikipedia:Brain] comment: include synganglion? subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "synganglion" RELATED [] synonym: "encephalon" RELATED [BTO:0000142] xref: BILA:0000135 xref: BTO:0000142 xref: EHDAA:2641 ! brain xref: EHDAA:6485 ! brain xref: EMAPA:16894 ! brain xref: FBbt:00005095 ! brain xref: FMA:50801 ! Brain xref: GAID:571 ! brain xref: galen:Brain xref: VHOG:0000157 ! brain xref: MA:0000168 ! brain xref: MAT:0000098 ! brain xref: MIAA:0000098 ! brain xref: NIF_GrossAnatomy:birnlex_796 ! Brain xref: OpenCyc:Mx4rvVjT65wpEbGdrcN5Y29ycA xref: TAO:0000008 ! brain xref: XAO:0000010 ! brain xref: ZFA:0000008 ! brain xref: ncithesaurus:Brain ! Brain xref: EFO:0000302 ! brain xref: OpenCyc:Mx4rvVjT65wpEbGdrcN5Y29ycA ! brain xref: EHDAA2:0000183 ! brain xref: MESH:A08.186.211 ! brain xref: EV:0100164 ! brain xref: ABA:Brain ! Basic cell groups and regions is_a: UBERON:0000062 {source="GO"} ! organ relationship: part_of UBERON:0001017 {source="FMA"} ! central nervous system xref: AAO:0010478 ! brain xref: SCTID:258335003 ! Entire brain property_value: external_definition "Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010478", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000008", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000157", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.165", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0006104 [Term] id: UBERON:0008823 name: neural tube derived brain is_a: UBERON:0000489 {source="ZFA"} ! cavitated compound organ comment: note that a reasoner should automatically classify all the vertebrate ontology brain classes here synonym: "vertebrate brain" NARROW [] intersection_of: UBERON:0000955 ! brain intersection_of: develops_from UBERON:0001049 ! neural tube relationship: immediate_transformation_of UBERON:0006238 {evidence="definitional"} ! future brain relationship: part_of UBERON:0000033 {source="FMA"} ! head def: "A brain that develops_from a neural tube." [OBOL:automatic] [Term] id: UBERON:0000956 name: cerebral cortex def: "The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2–4 mm (0.08–0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted]." [Wikipedia:Cerebral_cortex] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "cortex of cerebral hemisphere" EXACT [] synonym: "brain cortex" RELATED [BTO:0000233] synonym: "pallium of the brain" RELATED [BTO:0000233] xref: BTO:0000233 xref: EFO:0000328 ! cerebral cortex xref: EHDAA:5464 ! cerebral cortex xref: FMA:61830 ! Cerebral cortex xref: GAID:629 ! cerebral cortex xref: VHOG:0000722 ! cerebral cortex xref: MA:0000185 ! cerebral cortex xref: MAT:0000108 ! cerebral cortex xref: MIAA:0000108 ! cerebral cortex xref: NIF_GrossAnatomy:birnlex_1494 ! Cerebral cortex xref: ncithesaurus:Cortex ! Cerebral Cortex xref: EHDAA2:0000234 ! cerebral cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7b/Cerebral_Cortex_location.jpg/200px-Cerebral_Cortex_location.jpg xref: EMAPA:17544 ! cerebral cortex xref: MESH:A08.186.211.730.885.213 ! cerebral cortex xref: EV:0100166 ! cerebral cortex xref: ABA:CTX ! Cerebral cortex xref: BM:Tel-Cx ! cerebral cortex is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0000203 {source="GO", source="ISBN10:0471888893"} ! pallium relationship: has_function_in GO:0007613 {source="Wikipedia"} ! memory relationship: has_developmental_contribution_from UBERON:0004035 ! subplate relationship: has_developmental_contribution_from UBERON:0005343 ! cortical plate xref: SCTID:362880003 ! Entire cerebral cortex synonym: "cortex cerebri" RELATED LATIN [Wikipedia:Cerebral_cortex] xref: http://upload.wikimedia.org/wikipedia/commons/9/9a/Brainmaps-macaque-hippocampus.jpg property_value: homology_notes "Migration of neurons from the basal or striatal portions of the anterior part of the neural tube occurs to varying degrees in different vertebrate classes, but a true cerebral cortex is generally acknowledged to have made its first appearance in reptiles. The definition can be unambiguous, since 'cortex' simply implies the existence of a surface neuronal layer with an overlying 'zonal lamina' or 'molecular' layer containing dendrites and axons, which is separated from the underlying basal 'matrix' by white matter. Although reptilian cerebral cortex does indeed fulfill these conditions in certain locations, the separation from striatal structures is often indistinct, so that it may even be argued that some primitive dipnoans possess a pallium or cortex. Nevertheless, an extensive laminated layer separated by underlying white matter is well represented only in reptiles and mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0000722", ontology="VHOG", source="DOI:10.1111/j.1749-6632.1969.tb20437.x Kruger L\, Experimental analyses of the reptilian nervous system. Annals of the New York Academy of Sciences (1969)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0007776 [Term] id: UBERON:0000957 name: lamina def: "Any thin layer or plate." [Wikipedia:Lamina_of_the_vertebral_arch] comment: TODO - merge with cell layer? subset: uberon_slim subset: upper_level is_a: UBERON:0000479 ! portion of tissue xref: http://upload.wikimedia.org/wikipedia/commons/8/80/Laminaarcusvertebrae.png property_value: has_relational_adjective "laminal" xsd:string [Term] id: UBERON:0000958 name: medulla def: "Middle part of an organ (as opposed to the cortex)[WP]." [Wikipedia:Bone_marrow_of_ovary] comment: This class is used in a very general sense subset: upper_level xref: FMA:61108 ! Medulla xref: galen:Medulla ! medulla xref: BM:Me ! medulla is_a: UBERON:0000471 ! compound organ component relationship: surrounded_by UBERON:0001851 ! cortex property_value: has_relational_adjective "medullary" xsd:string [Term] id: UBERON:0000960 name: obsolete pharyngeal nerve def: "OBSOLETE. Original definition: The pharyngeal nerve (pterygopalatine nerve) is a small branch arising from the posterior part of the pterygopalatine ganglion. It passes through the pharyngeal canal with the pharyngeal branch of the maxillary artery, and is distributed to the mucous membrane of the nasal part of the pharynx, behind the auditory tube. [WP,unvetted]." [Wikipedia:Pharyngeal_nerve] subset: uberon_slim consider: FBbt:00004021 ! pharyngeal nerve consider: FMA:77524 ! Pharyngeal nerve consider: WBbt:0005441 ! pharyngeal nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d7/Gray780.png/200px-Gray780.png is_obsolete: true [Term] id: UBERON:0000961 name: thoracic ganglion def: "The thoracic ganglia are paravertebral ganglia. The thoracic portion of the sympathetic trunk typically has 12 thoracic ganglia. Emerging from the ganglia are thoracic splancic nerves (the cardiopulmonary, the greater, lesser, and least splanchic nerves) that help provide sympathetic innervation to abdominal structures. Also, the ganglia of the thoracic sympathetic trunk have both white and gray rami communicantes. The white rami carry sympathetic fibers arising in the spinal cord into the sympathetic trunk. [WP,unvetted]." [Wikipedia:Thoracic_ganglion] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "thoracic paravertebral ganglion" EXACT [] synonym: "thoracic splanchnic ganglion" EXACT [] synonym: "thoracic sympathetic ganglion" EXACT [] synonym: "ganglion of thorax" EXACT [OBOL:automatic] synonym: "thorax ganglion" EXACT [OBOL:automatic] xref: FMA:6471 ! Thoracic ganglion xref: VHOG:0000515 ! thoracic ganglion xref: MA:0001159 ! thoracic ganglion xref: ncithesaurus:Thoracic_Ganglion ! Thoracic Ganglion xref: BTO:0001831 ! thoracic ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3e/Gray849.png/200px-Gray849.png xref: RETIRED_EHDAA2:0002012 ! thoracic xref: EMAPA:17158 ! thoracic xref: EHDAA:4664 ! thoracic is_a: UBERON:0001807 ! paravertebral ganglion synonym: "ganglion thoracicum splanchnicum" EXACT LATIN [FMA:TA, FMA:6471] xref: SCTID:181102004 ! Entire thoracic sympathetic ganglion xref: UMLS:C0229010 [Term] id: UBERON:0000962 name: nerve of cervical vertebra def: "The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]." [Wikipedia:Cervical_nerves] comment: Innervates: sternohyoid muscle, sternothyroid muscle, omohyoid muscle[WP] subset: uberon_slim synonym: "cervical nerve tree" EXACT [] synonym: "cervical spinal nerve" EXACT [] synonym: "cervical nerve" EXACT [FMA:5859] xref: FMA:5859 ! cervical nerve xref: ncithesaurus:Cervical_Nerve ! Cervical Nerve xref: NIF_GrossAnatomy:nlx_anat_20090207 ! Cervical spinal nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Gray795.png/200px-Gray795.png is_a: UBERON:0001780 ! spinal nerve xref: SCTID:360497008 ! Entire cervical spinal nerve xref: UMLS:C0228815 [Term] id: UBERON:0000963 name: head sensillum comment: This class was created automatically from a combination of ontologies xref: FBbt:00004114 ! head sensillum xref: MAT:0000204 ! head sensillum xref: MIAA:0000204 ! head sensillum is_a: UBERON:0002536 ! arthropod sensillum [Term] id: UBERON:0012430 name: tunica fibrosa of eyeball xref: FMA:58102 ! fibrous layer of eyeball synonym: "fibrous layer of eyeball" EXACT [FMA:58102] synonym: "tunica fibrosa" BROAD [] is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0010230 ! eyeball of camera-type eye relationship: present_in_taxon NCBITaxon:7955 {source="doi:10.1177/0192623311409597"} ! Danio rerio [Term] id: UBERON:0000964 name: cornea def: "transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power." [Wikipedia:Cornea] comment: Taxon notes: Compared to terrestial animals, the cornea [of zebrafish] is relatively flat. It consists of nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman’s membrane in mammals subset: uberon_slim subset: vertebrate_core synonym: "cornea of camera-type eye" EXACT [GO:0061303] synonym: "tunica cornea" RELATED [] xref: BTO:0000286 xref: EFO:0000377 ! cornea xref: EHDAA:10199 ! cornea xref: FMA:58238 ! Cornea xref: GAID:892 ! cornea xref: VHOG:0000164 ! cornea xref: MA:0000266 ! cornea xref: ncithesaurus:Cornea xref: OpenCyc:Mx4rvViBa5wpEbGdrcN5Y29ycA xref: TAO:0000640 ! cornea xref: XAO:0000180 ! cornea xref: ZFA:0000640 ! cornea xref: OpenCyc:Mx4rvViBa5wpEbGdrcN5Y29ycA ! cornea xref: EHDAA2:0000316 ! cornea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: EMAPA:17161 ! cornea xref: MESH:A09.371.060.217 ! cornea xref: EV:0100341 ! cornea is_a: UBERON:0003102 ! surface structure relationship: develops_from UBERON:0005427 ! corneal primordium relationship: induced_by UBERON:0005426 ! lens vesicle relationship: continuous_with UBERON:0001773 ! sclera relationship: part_of UBERON:0001801 {source="MA"} ! anterior segment of eyeball relationship: part_of UBERON:0010409 {source="MA"} ! eye surface relationship: part_of UBERON:0012430 {source="FMA"} ! tunica fibrosa of eyeball xref: AAO:0010344 ! cornea xref: SCTID:181162001 ! Entire cornea relationship: develops_from UBERON:0004348 {evidence="definitional"} ! optic eminence xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg property_value: has_relational_adjective "corneal" xsd:string xref: UMLS:C0010031 [Term] id: UBERON:0005427 ! corneal primordium name: corneal primordium def: "Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea." [ZFIN:ZDB-PUB-061010-3] xref: ZFA:0001688 ! corneal primordium is_a: UBERON:0000479 {source="ZFA"} ! tissue is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: part_of UBERON:0000019 {source="ZFA"} ! camera-type eye relationship: develops_from UBERON:0002342 ! neural crest xref: TAO:0002188 ! corneal primordium [Term] id: UBERON:0011918 name: line of Schwalbe def: "The thickened peripheral margin of the vitreous membrane of the cornea." [MP:0006250] comment: AO notes: A line in FMA, a structure in MP synonym: "Schwalbe's ring" EXACT [MP:0006250] synonym: "Schwalbe line" EXACT [FMA:58422] synonym: "Schwalbe's line" EXACT [FMA:58422] is_a: UBERON:0006800 {source="FMA"} ! anatomical line relationship: part_of UBERON:0000964 ! cornea relationship: part_of UBERON:0005969 {source="MP"} ! reticulum trabeculare xref: FMA:58422 ! line of schwalbe [Term] id: UBERON:0005389 ! transparent eye structure name: transparent eye structure comment: transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array synonym: "lens" NARROW [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000970 ! eye [Term] id: UBERON:0000965 ! lens name: lens of camera-type eye def: "Transparent part of camera-type eye that helps to refract light to be focused on the retina." [Wikipedia:Lens_(anatomy)] comment: Taxon notes: This class excludes compound eye corneal lenses. subset: uberon_slim subset: vertebrate_core synonym: "lens" EXACT SENSU [] synonym: "eye lens" EXACT SENSU [] synonym: "camera-type eye lens" EXACT [GO:0002088] synonym: "crystalline lens" RELATED [BTO:0000723] synonym: "ocular lens" RELATED [BTO:0000723] synonym: "lens crystallina" EXACT [Wikipedia:Lens_%28anatomy%29] xref: BTO:0000723 xref: EHDAA:9057 ! lens xref: FMA:58241 ! Lens xref: VHOG:0000169 ! lens xref: MA:0000275 ! lens xref: MAT:0000141 ! lens xref: MIAA:0000141 ! lens xref: TAO:0000035 ! lens xref: XAO:0000008 ! lens xref: ZFA:0000035 ! lens xref: ncithesaurus:Crystalline_Lens ! Lens xref: OpenCyc:Mx4rvVj0fZwpEbGdrcN5Y29ycA ! lens xref: RETIRED_EHDAA2:0000975 ! lens xref: EMAPA:17838 ! lens xref: MESH:A09.371.509 ! crystalline len xref: EV:0100343 ! lens xref: AAO:0010348 ! lens is_a: UBERON:0005389 ! transparent eye structure relationship: develops_from UBERON:0003073 ! lens placode relationship: part_of UBERON:0001801 ! anterior segment of eyeball relationship: induced_by UBERON:0003902 ! retinal neural layer relationship: develops_from UBERON:0005426 ! lens vesicle disjoint_from: UBERON:0000207 ! compound eye corneal lens xref: AAO:0010348 ! lens xref: SCTID:181169005 ! Entire lens property_value: homology_notes "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {external_class="VHOG:0000169", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0023317 [Term] id: UBERON:0000207 ! compound eye corneal lens name: compound eye corneal lens def: "A chitinous extracellular secretion of the four underlying cone cells and the pigment cells." [GO:0048058] synonym: "acellular lens" RELATED [] xref: FBbt:00004199 ! lens xref: TADS:0000304 ! adult eye lens is_a: UBERON:0000476 ! acellular anatomical structure is_a: UBERON:0005389 ! transparent eye structure relationship: part_of UBERON:0000018 ! compound eye created_by: cjm creation_date: 2009-04-18T01:35:32Z [Term] id: UBERON:0000208 name: obsolete cellular lens created_by: cjm creation_date: 2009-04-18T01:37:39Z is_obsolete: true replaced_by: UBERON:0000965 ! lens [Term] id: UBERON:0005388 ! photoreceptor array name: photoreceptor array def: "An array of photoreceptors and any supporting cells found in an eye." [UBERON:cjm] synonym: "light-sensitive tissue" EXACT [] xref: FBbt:00004200 ! retina is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0000970 ! eye [Term] id: UBERON:0000966 name: retina def: "The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [Wikipedia:Retina, ZFIN:curator] comment: Currently this class encompasses only verteberate AOs but could in theory also include cephalopod - we may want to make a more specific class for vertebrate retina. note that this class excludes ommatidial retinas, as the retina must be part of an eyeball. Use the parent class photoreceptor array / light-sensitive tissue for arthropods subset: uberon_slim subset: vertebrate_core synonym: "retina of camera-type eye" EXACT [GO:0060041] synonym: "inner layer of eyeball" EXACT [] synonym: "tunica interna of eyeball" EXACT [] synonym: "Netzhaut" RELATED [BTO:0001175] xref: BTO:0001175 xref: EFO:0000832 ! retina xref: EHDAA:4757 ! retina xref: FMA:58301 ! Retina xref: GAID:755 ! retina xref: VHOG:0000229 ! retina xref: MA:0000276 ! retina xref: MAT:0000142 ! retina xref: MIAA:0000142 ! retina xref: ncithesaurus:Retina xref: NIF_GrossAnatomy:birnlex_1153 ! Retina xref: NIF_GrossAnatomy:birnlex_1156 xref: OpenCyc:Mx4rvViTfpwpEbGdrcN5Y29ycA xref: TAO:0000152 ! retina xref: XAO:0000009 ! retina xref: ZFA:0000152 ! retina xref: OpenCyc:Mx4rvViTfpwpEbGdrcN5Y29ycA ! retina xref: EHDAA2:0001627 ! retina xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Human_eye_cross-sectional_view_grayscale.png/200px-Human_eye_cross-sectional_view_grayscale.png xref: EMAPA:17168 ! retina xref: MESH:A09.371.729 ! retina xref: EV:0100348 ! retina is_a: UBERON:0005388 ! photoreceptor array relationship: develops_from UBERON:0003072 {source="EHDAA2"} ! optic cup relationship: part_of UBERON:0001802 ! posterior segment of eyeball relationship: never_in_taxon NCBITaxon:6656 ! Arthropoda relationship: has_part CL:0000573 {source="FMA"} ! retinal cone cell relationship: has_part CL:0000604 {source="FMA"} ! retinal rod cell relationship: has_part CL:0000740 {source="FMA"} ! retinal ganglion cell xref: AAO:0010352 ! retina xref: SCTID:181171005 ! Entire retina xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png property_value: external_definition "The portion of the eye developing from the optic primordium and including the neural retina and the retinal pigment layer. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000152", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {external_class="VHOG:0000229", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "retinal" xsd:string xref: UMLS:C0035298 [Term] id: UBERON:0000967 name: obsolete adult thoracic sensillum synonym: "thoracic sensillum" EXACT [] synonym: "arthropod sensillum of thorax" EXACT [OBOL:automatic] synonym: "sensillum of thorax" EXACT [OBOL:automatic] synonym: "thorax arthropod sensillum" EXACT [OBOL:automatic] synonym: "thorax sensillum" EXACT [OBOL:automatic] consider: FBbt:00004245 ! adult thoracic sensillum consider: MAT:0000205 ! thoracic sensillum consider: MIAA:0000205 ! thoracic sensillum is_obsolete: true [Term] id: UBERON:0000968 name: obsolete adult abdominal sensillum synonym: "abdominal sensillum" EXACT [] synonym: "abdomen arthropod sensillum" EXACT [OBOL:automatic] synonym: "abdomen sensillum" EXACT [OBOL:automatic] synonym: "arthropod sensillum of abdomen" EXACT [OBOL:automatic] synonym: "sensillum of abdomen" EXACT [OBOL:automatic] consider: FBbt:00004461 ! adult abdominal sensillum consider: MAT:0000206 ! abdominal sensillum consider: MIAA:0000206 ! abdominal sensillum is_obsolete: true [Term] id: UBERON:0000972 name: antenna def: "The paired, usually multiple jointed, sensory organs articulating on the procephalic region of the head capsule; its highly versatile sensory structures are capable to detect the various environmental stimuli. In the context of Drosophila refers to they are the most anterior segmented sensory appendage of the head." [FB:gg, ISBN:3110148986, Wikipedia:Antenna_(biology)] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology subset: uberon_slim synonym: "feeler" RELATED [BTO:0000074] xref: BTO:0000074 xref: EFO:0000874 ! antenna xref: FBbt:00004511 ! antenna xref: HAO:0000101 ! antenna xref: MAT:0000086 ! antenna xref: MIAA:0000086 ! antenna xref: OpenCyc:Mx4rvVjSAZwpEbGdrcN5Y29ycA ! antenna xref: TGMA:0000007 ! adult antenna xref: AEO:0000198 ! antenna is_a: UBERON:0000026 ! appendage relationship: part_of UBERON:0000033 ! head relationship: in_lateral_side_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda property_value: has_relational_adjective "antennal" xsd:string property_value: has_relational_adjective "antenno" xsd:string [Term] id: UBERON:0000973 name: obsolete labrum is_obsolete: true [Term] id: UBERON:0005905 name: insect labrum def: "A mouthpart of insects." [Wikipedia:Insect_mouthparts#Labrum] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology synonym: "labium" RELATED [BTO:0004104] synonym: "labrum" RELATED [BTO:0004104] synonym: "insect labium" EXACT [BTO:0004104] xref: BTO:0004104 ! insect labium xref: FBbt:00004522 ! labrum xref: HAO:0000456 ! labrum xref: TADS:0000039 ! adult labrum is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000165 ! mouth relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0000974 name: neck def: "Subdivision of body proper, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the cervical vertebral coumn, it is partially surrounded by skin of neck. Examples: There is only one neck[FMA]." [Wikipedia:Neck] comment: Usage notes: true necks are considered to be present when the pectoral girdle is separate from the skull - Tiktaalik is the earliest known fish to have a true neck. subset: uberon_slim xref: BTO:0000420 xref: FMA:7155 ! Neck xref: GAID:86 ! neck xref: MA:0000024 ! neck xref: MAT:0000297 ! neck xref: MIAA:0000297 ! neck xref: ncithesaurus:Neck ! Neck xref: EFO:0000967 ! neck xref: galen:Neck ! neck xref: OpenCyc:Mx4rvVjLF5wpEbGdrcN5Y29ycA ! neck xref: EHDAA2:0003108 ! neck xref: AEO:0000108 ! neck xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/99/Female_neck.jpg/200px-Female_neck.jpg xref: MESH:A01.598 ! neck is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000153 ! anterior region of body relationship: part_of UBERON:0007811 ! craniocervical region relationship: anteriorly_connected_to UBERON:0000033 ! head relationship: posteriorly_connected_to UBERON:0002100 ! trunk relationship: dubious_for_taxon NCBITaxon:32443 {source="ISBN:9780674021839"} ! Teleostei xref: SCTID:302550007 ! Entire neck synonym: "collum" RELATED LATIN [Wikipedia:Neck] synonym: "neck (volume)" RELATED [FMA:7155] property_value: has_relational_adjective "cervical" xsd:string xref: UMLS:C0027530 [Term] id: UBERON:0007811 name: craniocervical region def: "The anteriormost subdivision of the body that includes the head and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae." [UBERON:cjm] synonym: "head and neck" EXACT [FMA:280881] synonym: "head or neck" RELATED [] xref: MA:0000006 ! head and neck xref: EV:0100009 ! head and neck is_a: UBERON:0000475 {source="MA"} ! organism subdivision relationship: has_part UBERON:0000974 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! neck relationship: has_part UBERON:0000033 ! head relationship: part_of UBERON:0000153 ! anterior region of body xref: ncithesaurus:Head_and_Neck ! Head and Neck xref: galen:HeadAndNeck xref: SCTID:361355005 ! Entire head and neck xref: FMA:280881 ! craniocervical region xref: WikipediaCategory:Head_and_neck xref: UMLS:C0460004 xref: CALOHA:TS-2356 ! Head and neck [Term] id: UBERON:0008229 name: craniocervical region musculature synonym: "head or neck muscle" RELATED [MA:0000571] synonym: "head or neck muscle" EXACT [MA:0000571] xref: MA:0000571 ! head or neck muscle is_a: UBERON:0001015 {source="MA"} ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0007811 {source="MA"} ! craniocervical region def: "A musculature that is part of a craniocervical region." [OBOL:automatic] [Term] id: UBERON:0000975 name: sternum def: "A midventral endochondral skeletal element which represents the origin site of the pectoral muscles[PHENOSCAPE:ad]." [PHENOSCAPE:ad, Wikipedia:Sternum] comment: Development notes: While its developmental origins are similar to the ribs (from the myospetum and septum of the trunk region), it is often associated with the pectoral skeleton, due to both function and physical connections (i.e. the coracoid of archosaurs). It may be a single element or a series of smaller structure (sternebrae). Based on Kardong 2012. [ad]. Editor note: in EMAPA and EHDAA2 this is part of the skeleton of pectoral girdle; the classic def of pectoral girdle (see WP) excludes the rib cage and sternum. Taxon notes: It probably first evolved in early tetrapods as an extension of the pectoral girdle; it is not found in fish. In amphibians and reptiles it is typically a shield-shaped structure, often composed entirely of cartilage. It is absent in both turtles and snakes. In birds it is a relatively large bone and typically bears an enormous projecting keel to which the flight muscles are attached. Only in mammals does the sternum take on the elongated, segmented form seen in humans. In some mammals, such as opossums, the individual segments never fuse and remain separated by cartilagenous plates throughout life[WP] subset: uberon_slim synonym: "vertebrate sternum" EXACT [] synonym: "breastbone" RELATED [BTO:0001302] xref: AAO:0000765 ! sternum xref: BTO:0001302 xref: FMA:7485 ! Sternum xref: GAID:246 ! sternum xref: VHOG:0000856 ! sternum xref: MA:0001331 ! sternum xref: OpenCyc:Mx4rvVjO6JwpEbGdrcN5Y29ycA xref: ncithesaurus:Sternum ! Sternum xref: EHDAA:9561 ! sternum xref: galen:Sternum ! sternum xref: OpenCyc:Mx4rvVjO6JwpEbGdrcN5Y29ycA ! sternum xref: EHDAA2:0001914 ! sternum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/12/Illu_thoracic_cage.jpg/200px-Illu_thoracic_cage.jpg xref: EMAPA:18344 ! sternum xref: MESH:A02.835.232.904.766 ! sternum is_a: UBERON:0010363 {source="Kardong"} ! endochondral element relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0003252 {source="FMA"} ! rib cage relationship: connected_to UBERON:0002228 ! rib relationship: connected_to UBERON:0007831 ! pectoral girdle skeleton relationship: only_in_taxon NCBITaxon:32523 {source="Kardong"} ! Tetrapoda relationship: never_in_taxon NCBITaxon:8570 {source="Wikipedia"} ! Serpentes xref: SCTID:302522007 ! Entire sternum relationship: connected_to UBERON:0008255 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! right clavicle relationship: connected_to UBERON:0008256 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! left clavicle property_value: external_definition "Single element that constitutes the postzonal area of the pectoral girdle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000765", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of postzonal element (AAO:0000938)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000765", date_retrieved="2012-06-20"} property_value: homology_notes "Fishes lack a sternum. (...) A sternum is absent in the first fossil tetrapods, but it is present in modern amphibians. (...) Thus, a sternum occurs in some modern amphibians, birds, mammals and archosaurs. However, its absence in the common ancestors to these groups means that it has arisen independently several times within the field of the midventral connective tissue.[well established][VHOG]" xsd:string {external_class="VHOG:0000856", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.294", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "sternal" xsd:string xref: UMLS:C0038293 [Term] id: UBERON:0000976 name: humerus def: "Paired endochondral long bone that extends between the pectoral girdle and the skeletal parts of the forelimb. [PHENOSCAPE:mah]" [PHENOSCAPE:mah, Wikipedia:Humerus, AAO:0000679] comment: homologous to proximal metapterygial mesomere of pectoral appendage [Hall 2007] subset: uberon_slim synonym: "humerus bone" EXACT [] synonym: "humeri" EXACT PLURAL [PHENOSCAPE:ad] xref: AAO:0000679 ! humerus xref: FMA:13303 ! Humerus xref: GAID:183 ! humerus xref: galen:Humerus xref: VHOG:0001158 ! humerus xref: MA:0001356 ! humerus xref: ncithesaurus:Humerus ! Humerus xref: EFO:0001398 ! humerus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/67/Illu_upper_extremity.jpg/200px-Illu_upper_extremity.jpg xref: XAO:0003210 ! humerus xref: EMAPA:18468 ! humerus of mesenchyme of upper arm xref: EMAPA:19106 ! humerus of upper arm xref: MESH:A02.835.232.087.412 ! humerus is_a: UBERON:0002495 {source="FMA"} ! long bone relationship: part_of UBERON:0001440 {source="FMA"} ! forelimb skeleton relationship: part_of UBERON:0003822 {source="FMA"} ! forelimb stylopod relationship: proximally_connected_to UBERON:0007831 ! pectoral girdle skeleton xref: SCTID:181923006 ! Entire humerus relationship: develops_from UBERON:0006245 {evidence="definitional"} ! humerus cartilage condensation xref: http://upload.wikimedia.org/wikipedia/commons/6/67/Illu_upper_extremity.jpg property_value: external_definition "Paired, elongate, cylindrical bones of endochondral origin that extend from the pectoral girdle to the elbows.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000679", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0001158", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "humeral" xsd:string xref: UMLS:C0020164 [Term] id: UBERON:0010703 ! forelimb zeugopod skeleton name: forelimb zeugopod skeleton def: "The collection of all skeletal elements in an forelimb zeugopod region." [UBERON:cjm] synonym: "wing zeugopod skeleton" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] comment: Editor notes: adding proxinally_connected_to humerus causes inconsistencies - requires investigation synonym: "antebrachium skeleton" EXACT [PHENOSCAPE:ni] synonym: "antebrachial skeleton" EXACT [] synonym: "forearm skeleton" EXACT [FMA:71199] synonym: "forelimb epipodium" RELATED [VSAO:NI, VSAO:0005011] synonym: "forelimb epipodium skeleton" RELATED [] synonym: "anterior zeugopodium" RELATED [VSAO:NI, VSAO:0005011] synonym: "anterior zeugopodium skeleton" EXACT [VSAO:NI, VSAO:0005011] synonym: "skeleton of forearm" EXACT [FMA:71199] synonym: "fore epipodium" RELATED [AAO:0000200] synonym: "fore epipodium skeleton" EXACT [] synonym: "radius and ulna" RELATED [] xref: FMA:71199 ! skeleton of forearm xref: VSAO:0005011 ! anterior zeugopodium xref: AAO:0000200 ! fore epipodium intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: subdivision_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0001440 ! forelimb skeleton !relationship: proximally_connected_to UBERON:0000976 ! humerus property_value: external_definition "Segment of the forearm corresponding to the radius and ulna.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000200", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0001423 name: radius bone def: "The major preaxial endochondral bone in the anterior zeugopod[Phenoscape]." [PHENOSCAPE:mah, Wikipedia:Radius_(bone)] comment: Due to the presence of the radius in Tetrpodomorph fish this element is not inherently linked to the presence of digits or flexor musculature. The corresponding bone in the posterior fin/limb is the tibia.[Phenoscape]. In four-legged animals, the radius is the main load-bearing bone of the lower forelimb. Its structure is similar in most terrestrial tetrapods, but it may be fused with the ulna in some mammals (such as horses) and reduced or modified in animals with flippers or vestigial forelimbs [ISBN:0-03-910284-X] subset: uberon_slim synonym: "radius" EXACT [MA:0001357] xref: AAO:0000788 ! radius xref: FMA:23463 ! Radius xref: GAID:185 ! radius xref: MA:0001357 ! radius xref: galen:Radius ! radius xref: OpenCyc:Mx4rwUsDcZwpEbGdrcN5Y29ycA ! radius xref: EMAPA:18466 ! radius of mesenchyme of forearm xref: EMAPA:19103 ! radius of forearm xref: MESH:A02.835.232.087.702 ! radius xref: ncithesaurus:Radius_Bone ! Radius Bone xref: SCTID:181940002 ! Entire radius xref: VSAO:0005012 ! radius is_a: UBERON:0002495 ! long bone relationship: preaxial_part_of UBERON:0010703 ! forelimb zeugopod skeleton relationship: part_of UBERON:0010703 {source="VSAO"} ! forelimb zeugopod skeleton relationship: develops_from UBERON:0006286 {evidence="definitional"} ! radius cartilage condensation property_value: external_definition "One of the two long bones of endochondral origin of the fore-epipodium; it is located on the lateral side of the ulna. Its upper end articulates with both the humerus and the ulna, whereas the lower articulates with the carpals.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000788", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0034627 [Term] id: UBERON:0006286 name: radius cartilage condensation xref: EMAPA:18054 ! radius cartilage condensation xref: EHDAA2:0001585 ! radius cartilage condensation xref: VHOG:0001318 ! radius cartilage condensation xref: EHDAA:7267 ! radius cartilage condensation intersection_of: UBERON:0005863 ! cartilagenous condensation intersection_of: develops_into UBERON:0001423 ! radius relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton relationship: part_of UBERON:0003327 {source="EHDAA2"} ! mesenchyme of forearm def: "A cartilaginous condensation that develops_into a radius bone." [OBOL:automatic] [Term] id: UBERON:0010846 name: radius pre-cartilage condensation comment: Editor notes: still to decide whether this is a distinct pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0001423 ! radius relationship: part_of UBERON:0003327 {source="EHDAA2"} ! mesenchyme of forearm relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton relationship: develops_from UBERON:0006287 {source="EHDAA2"} ! radius-ulna pre-cartilage condensation xref: EHDAA2:0001586 ! radius pre-cartilage condensation def: "A pre-cartilage condensation that develops_into a radius bone." [OBOL:automatic] [Term] id: UBERON:0006287 name: radius-ulna pre-cartilage condensation comment: AO notes: EMAPA has a separate radius-ulna cartilage condensation. xref: EMAPA:17420 ! radius-ulna pre-cartilage condensation xref: EHDAA2:0001587 ! radius-ulna pre-cartilage condensation xref: VHOG:0000949 ! radius-ulna pre-cartilage condensation xref: EHDAA:4178 ! radius-ulna pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0003327 ! mesenchyme of forearm [Term] id: UBERON:0010848 ! radius-ulna cartilage condensation name: radius-ulna cartilage condensation comment: AO notes: note that this is not represented as a single unit in EHDAA2 synonym: "radio-ulna cartilage condensation" EXACT [EMAPA:17711] is_a: UBERON:0005863 ! cartilagenous condensation relationship: part_of UBERON:0003327 {source="EMAPA"} ! mesenchyme of forearm relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton relationship: develops_from UBERON:0006287 ! radius-ulna pre-cartilage condensation xref: EMAPA:17711 ! radius-ulna cartilage condensation [Term] id: UBERON:0001424 name: ulna def: "The major postaxial endochondral bone in the anterior zeugopod[Phenoscape]." [PHENOSCAPE:mah, Wikipedia:Ulna] comment: The corresponding bone in the posterior fin/limb is the fibula. subset: uberon_slim xref: AAO:0000789 ! ulna xref: FMA:23466 ! Ulna xref: GAID:188 ! ulna xref: MA:0001358 ! ulna xref: ncithesaurus:Ulna ! Ulna xref: galen:Ulna ! ulna xref: OpenCyc:Mx4rwPtIM5wpEbGdrcN5Y29ycA ! ulna xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/67/Illu_upper_extremity.jpg/200px-Illu_upper_extremity.jpg xref: EMAPA:18467 ! ulna of mesenchyme of forearm xref: EMAPA:19104 ! ulna of forearm xref: MESH:A02.835.232.087.911 ! ulna xref: SCTID:181948009 ! Entire ulna xref: VSAO:0005013 ! ulna is_a: UBERON:0002495 ! long bone relationship: postaxial_part_of UBERON:0010703 ! forelimb zeugopod skeleton relationship: part_of UBERON:0010703 {source="VSAO"} ! forelimb zeugopod skeleton relationship: develops_from UBERON:0006306 {evidence="definitional"} ! ulna cartilage condensation xref: http://upload.wikimedia.org/wikipedia/commons/6/67/Illu_upper_extremity.jpg property_value: external_definition "One of the two long bones of endochondral origin of the fore-epipodium; it is located on the medial (inner) side of the radius. The upper end of the ulna articulates with the lower end of the humerus forming a strong hinge joint with the carpals, whereas the lower articulates with the carpals.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000789", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: has_relational_adjective "ulnar" xsd:string xref: UMLS:C0041600 [Term] id: UBERON:0006306 name: ulna cartilage condensation xref: EMAPA:18055 ! ulna cartilage condensation xref: EHDAA2:0002098 ! ulna cartilage condensation xref: VHOG:0001155 ! ulna cartilage condensation xref: EHDAA:7269 ! ulna cartilage condensation is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005863 ! cartilagenous condensation intersection_of: develops_into UBERON:0001424 ! ulna relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton relationship: part_of UBERON:0003327 ! mesenchyme of forearm def: "A cartilaginous condensation that develops_into a ulna." [OBOL:automatic] [Term] id: UBERON:0010847 name: ulna pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0001424 ! ulna relationship: develops_from UBERON:0006287 {source="EHDAA2"} ! radius-ulna pre-cartilage condensation relationship: part_of UBERON:0003327 {source="EHDAA2"} ! mesenchyme of forearm relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton xref: EHDAA2:0002100 ! ulna pre-cartilage condensation xref: EHDAA:6226 ! ulna pre-cartilage condensation def: "A pre-cartilage condensation that develops_into a ulna." [OBOL:automatic] [Term] id: UBERON:0000979 name: tibia def: "The major preaxial endochondral bone in the posterior zeugopod[Phenoscape]." [PHENOSCAPE:mah, Wikipedia:Tibia] subset: uberon_slim synonym: "shankbone" EXACT [Wikipedia:Tibia] synonym: "shinbone" EXACT [Wikipedia:Tibia] xref: AAO:0000890 ! tibia xref: BTO:0001252 xref: FMA:24476 ! Tibia xref: GAID:204 ! tibia xref: MA:0001361 ! tibia xref: ncithesaurus:Tibia ! Tibia xref: galen:Tibia ! tibia xref: OpenCyc:Mx4rvtq3-ZwpEbGdrcN5Y29ycA ! shinbone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2a/Gray260.png/200px-Gray260.png xref: EMAPA:19142 ! tibia xref: MESH:A02.835.232.500.883 ! tibia xref: EFO:0003054 ! tibia is_a: UBERON:0002495 {source="FMA"} ! long bone relationship: preaxial_part_of UBERON:0010720 ! hindlimb zeugopod skeleton relationship: part_of UBERON:0010720 ! hindlimb zeugopod skeleton relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: SCTID:182061009 ! Entire tibia relationship: develops_from UBERON:0010849 ! tibia cartilaginous condensation xref: http://upload.wikimedia.org/wikipedia/commons/2/2a/Gray260.png property_value: external_definition "One of the two long bones of endochondral origin of the hind-epipodium; it is a straight, simple bone whose section is more or less rectangular at the ends and circular at its central portion.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000890", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0040184 [Term] id: UBERON:0010849 name: tibia cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0000979 ! tibia relationship: part_of UBERON:0010720 ! hindlimb zeugopod skeleton relationship: part_of UBERON:0005259 {source="EMAPA"} ! lower leg mesenchyme relationship: develops_from UBERON:0010850 ! tibia pre-cartilage condensation xref: EMAPA:18155 ! tibia cartilage condensation def: "A cartilaginous condensation that develops_into a tibia." [OBOL:automatic] [Term] id: UBERON:0010850 name: tibia pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0000979 ! tibia relationship: part_of UBERON:0010720 ! hindlimb zeugopod skeleton relationship: part_of UBERON:0005259 {source="EHDAA2"} ! lower leg mesenchyme xref: EHDAA2:0002036 ! tibia pre-cartilage condensation def: "A pre-cartilage condensation that develops_into a tibia." [OBOL:automatic] [Term] id: UBERON:0000313 name: tibial cartilage def: "Cartilage pertaining to the tibia." [Dorlands_Medical_Dictionary:MerckSource] comment: TODO synonym: "cartilage of tibia" EXACT [FMA:33923] xref: BTO:0000207 xref: FMA:33923 ! Cartilage of tibia intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0000979 ! tibia [Term] id: UBERON:0000981 name: femur def: "Endochondral longbone connecting the pelvic girdle with posterior zeugopodium skeleton.[VSAO, modified]." [Wikipedia:Femur, VSAO:0000186] comment: homologous to proximal metapterygial mesomere of pelvic appendage [Hall 2007]. subset: uberon_slim synonym: "thigh bone" EXACT [] synonym: "femoral bone" RELATED [BTO:0001284] synonym: "os femorale" RELATED [BTO:0001284] synonym: "os femoris" RELATED [BTO:0001284] xref: AAO:0000889 ! femur xref: BTO:0001284 xref: FMA:9611 ! Femur xref: GAID:199 ! femur xref: galen:Femur xref: VHOG:0001159 ! femur xref: MA:0001359 ! femur xref: OpenCyc:Mx4rvVjOJJwpEbGdrcN5Y29ycA xref: ncithesaurus:Femur ! Femur xref: EFO:0001396 ! femur xref: OpenCyc:Mx4rvVjOJJwpEbGdrcN5Y29ycA ! femur xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/73/Gray252.png/200px-Gray252.png xref: XAO:0003214 ! femur xref: EMAPA:18514 ! femur of mesenchyme of upper leg xref: EMAPA:19143 ! femur of upper leg xref: MESH:A02.835.232.500.247 ! femur xref: VSAO:0000186 ! femur is_a: UBERON:0002495 ! long bone is_a: UBERON:0008202 {source="MA"} ! bone of hip region relationship: proximally_connected_to UBERON:0007832 ! pelvic girdle skeleton relationship: part_of UBERON:0001441 {source="FMA"} ! hindlimb skeleton relationship: part_of UBERON:0000376 {source="FMA"} ! hindlimb stylopod relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: develops_from UBERON:0010129 {evidence="definitional"} ! femur cartilage condensation xref: SCTID:182046008 ! Entire femur relationship: connected_to UBERON:0001272 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! innominate bone relationship: connected_to UBERON:0002446 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! patella relationship: connected_to UBERON:0000979 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tibia synonym: "os femoris, os longissimum" RELATED LATIN [Wikipedia:Femur] xref: http://upload.wikimedia.org/wikipedia/commons/7/73/Gray252.png property_value: external_definition "Paired, elongate, cylindrical bones of endochondral origin that form the thighs, extending from the pelvic girdles to the knees.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000889", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Endochondral longbone connecting the pelvic girdle with posterior zeugopodium.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000186", date_retrieved="2012-08-14", source="VSAO:NI"} property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0001159", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "femoral" xsd:string xref: UMLS:C0015811 [Term] id: UBERON:0006767 name: head of femur def: "The hemispheric articular surface at the upper extremity of the thigh bone[Stedman, 26th ed]. The femur head is the highest part of the thigh bone. It is supported by the neck of the femur. The head is globular and forms rather more than a hemisphere, is directed upward, medialward, and a little forward, the greater part of its convexity being above and in front. Its surface is smooth, coated with cartilage in the fresh state, except over an ovoid depression, the fovea capitis femoris, which is situated a little below and behind the center of the head, and gives attachment to the ligament of head of femur. If there is a fracture of the neck of the femur, the blood supply through the ligament becomes crucial. In orthopedic surgery, the head of the femur is important because it can undergo avascular necrosis and consequent osteochondritis dissecans. The head is removed in total hip replacement surgery [WP]." [Wikipedia:Femur_head, MESH:A02.835.232.500.247.343] synonym: "femur head" RELATED [MESH:A02.835.232.500.247.343] synonym: "acetabular head" EXACT [AAO:0000892] synonym: "caput femoris" RELATED [AAO:0000892, Wikipedia:Femur_head] synonym: "femoral head" EXACT [FMA:32851] synonym: "capital femoral epiphysis" RELATED [http://medical-dictionary.thefreedictionary.com/capital+femoral+epiphysis] xref: MESH:A02.835.232.500.247.343 ! femur head xref: FMA:32851 ! Head of femur xref: AAO:0000892 ! acetabular head is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004412 ! proximal epiphysis of femur relationship: adjacent_to UBERON:0001269 ! acetabular part of hip bone xref: ncithesaurus:Head_of_the_Femur ! Head of the Femur xref: galen:FemoralHead xref: SCTID:361791000 ! Entire head of femur synonym: "caput femoris" RELATED LATIN [Wikipedia:Femur_head] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Gray243.png property_value: external_definition "Proximal head of the femur, which articulates with the acetabulum.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000892", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0015813 [Term] id: UBERON:0012078 name: fovea capitis of femur def: "The surface of the head of the femur is smooth, coated with cartilage in the fresh state, except over an ovoid depression, the fovea of head of femur, which is situated a little below and behind the center of the head, and gives attachment to the ligamentum teres." [Wikipedia:Fovea_of_head_of_femur] comment: Absent in pinnipeds synonym: "fovea of head of femur" RELATED [Wikipedia:Fovea_of_head_of_femur] synonym: "fovea capitis" BROAD [Wikipedia:Fovea_of_head_of_femur] synonym: "fovea capitis of femoral head" EXACT [] synonym: "fovea capitis femoris" EXACT LATIN [Wikipedia:Fovea_of_head_of_femur] synonym: "fovea capitis femoris (caput femoris)" EXACT [FMA:43700] synonym: "fovea for ligament of head of femur" EXACT [FMA:43700] xref: FMA:43700 ! fovea for ligament of head of femur is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004412 ! proximal epiphysis of femur [Term] id: UBERON:0007119 name: neck of femur def: "The femur neck or neck of the femur is a flattened pyramidal process of bone, connecting the femoral head with the femoral shaft, and forming with the latter a wide angle opening medialward." [Wikipedia:Femur_neck] synonym: "femoral neck" RELATED [Wikipedia:Femur_neck] synonym: "neck of femur" RELATED [Wikipedia:Femur_neck] synonym: "femur neck" RELATED [Wikipedia:Femur_neck] synonym: "neck of the femur" RELATED [Wikipedia:Femur_neck] synonym: "femoral neck" EXACT [FMA:42385] xref: FMA:42385 ! neck of femur xref: MESH:A02.835.232.500.247.510 xref: GAID:201 ! femur neck is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0006863 ! proximal metaphysis of femur xref: ncithesaurus:Femoral_Neck ! Femoral Neck xref: galen:NeckOfFemur xref: SCTID:361792007 ! Entire neck of femur synonym: "collum femoris" RELATED LATIN [Wikipedia:Femur_neck] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Gray243.png xref: UMLS:C0015815 [Term] id: UBERON:0004905 ! articulation name: articulation def: "anatomical cluster that connects two or more adjacent skeletal elements or hardened body parts." [] synonym: "joint" NARROW [] subset: grouping_class xref: FBbt:00005811 ! articulation is_a: UBERON:0000477 ! anatomical cluster [Term] id: UBERON:0000982 name: skeletal joint def: "Anatomical cluster that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]." [VSAO:0000101, Wikipedia:Joint] subset: uberon_slim subset: vertebrate_core synonym: "joint" BROAD [FMA:7490, VSAO:0000101] synonym: "articular joint" RELATED [BTO:0001686] synonym: "articulation" BROAD [VSAO:0000101] xref: FMA:7490 ! Joint xref: GAID:102 ! joint xref: galen:Joint xref: VHOG:0001276 ! joint xref: MA:0000319 ! joint xref: MAT:0000188 ! joint xref: MIAA:0000188 ! joint xref: RETIRED_EHDAA2:0003182 ! joint xref: AEO:0000182 ! joint xref: OpenCyc:Mx4rvVjjdpwpEbGdrcN5Y29ycA xref: TAO:0000367 ! joint xref: XAO:0000171 ! joint xref: ZFA:0001596 ! joint xref: ncithesaurus:Joint ! Joint xref: BTO:0001686 ! joint xref: EFO:0000948 ! joint xref: MESH:A02.835.583 ! joint xref: SCTID:302536002 ! Entire joint xref: VSAO:0000101 ! joint is_a: UBERON:0004905 ! articulation relationship: connects UBERON:0004765 ! skeletal element relationship: part_of UBERON:0004770 ! articular system disjoint_from: UBERON:0001474 ! bone element union_of: UBERON:0011134 ! nonsynovial joint union_of: UBERON:0002217 ! synovial joint subset: organ_slim property_value: external_definition "Anatomical cluster which consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000367", date_retrieved="2012-08-14", source="TAO:pem"} property_value: external_definition "Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000101", date_retrieved="2012-08-14", source="PSPUB:0000170"} xref: UMLS:C0022417 [Term] id: UBERON:0002217 name: synovial joint def: "Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]" [Wikipedia:Synovial_joint, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "articulatio synoviale" EXACT [] synonym: "diarthrodial joints" RELATED PLURAL [ZFA:0005153] synonym: "diarthroses" EXACT PLURAL [ZFA:0005153] synonym: "diarthrosis" EXACT [] synonym: "diarthrosis joint" EXACT [] xref: FMA:7501 ! Synovial joint xref: MA:0000322 ! synovial joint xref: OpenCyc:Mx4rv2bBV5wpEbGdrcN5Y29ycA xref: ZFA:0005153 ! synovial joint xref: galen:SynovialJoint ! synovial joint xref: OpenCyc:Mx4rv2bBV5wpEbGdrcN5Y29ycA ! synovial joint xref: EHDAA2:0003183 ! synovial joint xref: AEO:0000183 ! synovial joint is_a: UBERON:0000982 ! skeletal joint xref: SCTID:113234001 ! Entire synovial joint xref: TAO:0005153 ! synovial joint property_value: external_definition "Is a joint that is located at the point of contact of articulating bones allowing movement. The joint has a capsule containing synovial fluid surrounding the articulating bone surfaces.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005153", date_retrieved="2012-08-14", source="ZFIN:Curator"} [Term] id: UBERON:0011134 ! nonsynovial joint name: nonsynovial joint def: "Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis." [FMA:7491] synonym: "solid joint" EXACT [FMA:7491] is_a: UBERON:0000982 {source="FMA"} ! skeletal joint disjoint_from: UBERON:0002217 ! synovial joint xref: FMA:7491 ! nonsynovial joint [Term] id: UBERON:0011866 name: condylar joint is_a: UBERON:0002217 ! synovial joint def: "In a condyloid joint (condyloid articulation, ellipsoidal joint) an ovoid articular surface, or condyle, is received into an elliptical cavity. This permits movement in two planes, allowing flexion, extension, adduction, abduction, and circumduction." [Wikipedia:Condyloid_joint] synonym: "condylar joint" RELATED [Wikipedia:Condyloid_joint] synonym: "condyloid" RELATED [Wikipedia:Condyloid_joint] synonym: "condyloid articulation" RELATED [Wikipedia:Condyloid_joint] synonym: "condyloid joints" RELATED [Wikipedia:Condyloid_joint] synonym: "ellipsoidal joint" RELATED [Wikipedia:Condyloid_joint] synonym: "articulatio ellipsoidea" RELATED LATIN [Wikipedia:Condyloid_joint] xref: FMA:75300 ! condylar joint xref: SCTID:335493003 ! Entire condylar joint [Term] id: UBERON:0011873 name: synarthrosis def: "A synarthrosis is a type of joint which permits very little or no movement under normal conditions. Most synarthrosis joints are fibrous. Suture joints and synchondroses are synarthroses." [Wikipedia:Synarthrosis] synonym: "synarthrodial joint" RELATED [Wikipedia:Synarthrosis] synonym: "synarthrodial" RELATED [Wikipedia:Synarthrosis] synonym: "synarthroses" RELATED [Wikipedia:Synarthrosis] is_a: UBERON:0000982 ! skeletal joint xref: ncithesaurus:Synarthrosis ! synarthrosis xref: UMLS:C0699803 [Term] id: UBERON:0011874 name: amphiarthrosis def: "Amphiarthrosis is a type of continuous, slightly movable joint." [Wikipedia:Amphiarthrosis] synonym: "amphiarthrodial" RELATED [Wikipedia:Amphiarthrosis] synonym: "amphiarthroses" RELATED [Wikipedia:Amphiarthrosis] is_a: UBERON:0000982 ! skeletal joint xref: FMA:76693 ! amphiarthrosis xref: ncithesaurus:Amphiarthrosis ! amphiarthrosis xref: UMLS:C0224520 [Term] id: UBERON:0004772 name: eyelid tarsus def: "The tarsi (tarsal plates) are two comparatively thick, elongated plates of dense connective tissue, about 2.5 cm. in length; one is found in each eyelid, and contributes to its form and support. They directly abut the lid margins." [Wikipedia:Tarsus_(eyelids)] comment: Taxon notes: In most taxa (birds, mammals, lizards), the tarsal plate is described as a dense, fibrous connective tissue, possibly including cartilage, present within one or both of the upper and lower eyelids (Gau- thier et al., 1988; Rieppel, 2000). In humans, the tarsal plate of the upper eyelid is composed of collagens types I, III, and V, as well as glycosaminogly- cans (chondroitin sulphate 4 and 6), aggrecan, and cartilage oligomeric matrix proteins but lacks collagen type II as well as chondrocytes (Milz et al., 2005). Thus, for humans, the upper tarsal plate represents neither a truly fibrous nor a truly cartilagi- nous element but instead one that is composed of a unique transitional tissue (Milz et al., 2005). In many birds, lizards, and Sphenodon (the tuatara), the upper eyelid has lim- ited mobility and a putative tarsal plate is instead found within the lower eyelid (Underwood, 1970; Gau- thier et al., 1988). [PMID:16496288] synonym: "tarsus palpebralis" EXACT [PMID:16496288] synonym: "tarsal plate" EXACT [] synonym: "tarsi" RELATED PLURAL [] synonym: "eyelid tarsi" RELATED PLURAL [] synonym: "tarsal plate of eyelid" EXACT [FMA:59086] synonym: "tarsal plate" EXACT [FMA:59086] xref: MA:0000270 ! eyelid tarsus xref: FMA:59086 ! tarsal plate of eyelid is_a: UBERON:0000094 {source="FMA"} ! membrane organ relationship: part_of UBERON:0001711 {source="FMA"} ! eyelid relationship: part_of UBERON:0003581 {source="cjm"} ! eyelid connective tissue disjoint_from: UBERON:0004454 ! tarsal region xref: ncithesaurus:Tarsal_Plate ! Tarsal Plate xref: SCTID:362529005 ! Entire tarsal plate subset: organ_slim xref: UMLS:C0459586 [Term] id: UBERON:0004773 name: superior eyelid tarsus def: "An eyelid tarsus that is part of a upper eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "tarsus of upper eyelid" EXACT [] synonym: "tarsal plate of upper eyelid" EXACT [FMA:59087] synonym: "superior tarsal plate" EXACT [FMA:59087] synonym: "superior tarsus of eyelid" EXACT [] synonym: "superior tarsus" EXACT [FMA:59087] xref: FMA:59087 ! tarsal plate of upper eyelid xref: MA:0001260 ! superior eyelid tarsus intersection_of: UBERON:0004772 ! eyelid tarsus intersection_of: part_of UBERON:0001712 ! upper eyelid synonym: "tarsus superior" EXACT LATIN [FMA:TA, FMA:59087] xref: SCTID:368773004 ! Entire superior tarsal plate [Term] id: UBERON:0004774 name: inferior eyelid tarsus def: "An eyelid tarsus that is part of a lower eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "tarsus of lower eyelid" EXACT [] synonym: "tarsal plate of lower eyelid" EXACT [FMA:59088] synonym: "inferior tarsal plate" EXACT [FMA:59088] synonym: "inferior tarsus of eyelid" EXACT [] synonym: "inferior tarsus" EXACT [FMA:59088] xref: FMA:59088 ! tarsal plate of lower eyelid xref: MA:0001257 ! inferior eyelid tarsus intersection_of: UBERON:0004772 ! eyelid tarsus intersection_of: part_of UBERON:0001713 ! lower eyelid synonym: "tarsus inferior" EXACT LATIN [FMA:TA, FMA:59088] xref: SCTID:368774005 ! Entire inferior tarsal plate [Term] id: UBERON:0010379 name: superior tarsal muscle def: "The superior tarsal muscle is a smooth muscle adjoining the levator palpebrae superioris muscle that helps to raise the upper eyelid." [Wikipedia:Superior_tarsal_muscle] comment: Editors note: declaring this to be both smooth muscle and part of the LPS leads to a disjointness violation (smooth muscle and striated muscle) synonym: "mueller muscle" RELATED [Wikipedia:Superior_tarsal_muscle] synonym: "Muller's muscle" RELATED [Wikipedia:Superior_tarsal_muscle] synonym: "Müller's muscle" RELATED [Wikipedia:Superior_tarsal_muscle] synonym: "the superior tarsal muscle" RELATED [Wikipedia:Superior_tarsal_muscle] synonym: "Mueller's muscle" EXACT [FMA:49058] is_a: UBERON:0001135 ! smooth muscle tissue relationship: continuous_with UBERON:0001604 {source="FMA"} ! levator palpebrae superioris relationship: part_of UBERON:0001712 ! upper eyelid xref: FMA:49058 ! superior tarsal muscle relationship: innervated_by UBERON:0000013 {source="dbpedia"} ! sympathetic nervous system synonym: "musculus tarsalis superior" RELATED LATIN [Wikipedia:Superior_tarsal_muscle] relationship: has_muscle_origin UBERON:0001604 {source="dbpedia", notes="underside of levator palpebrae superioris"} ! levator palpebrae superioris xref: http://upload.wikimedia.org/wikipedia/commons/6/6f/Gray894.png xref: SCTID:244775007 ! Entire superior tarsal muscle [Term] id: UBERON:0010309 name: palpebral bone def: "An ossified element investing the upper eyelid." [Wikipedia:Palpebral_(bone), PMID:16496288] comment: Taxon notes: The most extreme development of the palpebral is found in the armored dino- saur Euoplocephalus tutus, where the bone forms a quarter-sphere and adducts to completely occlude the or- bit (Coombs, 1972; Vickaryous and Russell, 2003). Notwithstanding the superficially similar position, palpe- brals and tarsal plates differ both anatomically and developmentally and are not considered homologous (Gauthier et al., 1988). Editor notes PMID:16496288 says 'invests' the eyelid, is this consistent across taxa? synonym: "palpebral" EXACT [] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001712 ! upper eyelid relationship: only_in_taxon NCBITaxon:8457 ! Sauropsida [Term] id: UBERON:0000984 name: imaginal disc-derived wing def: "A flight organ of the adult external thorax that is derived from a dorsal mesothoracic disc." [FB:gg] comment: TODO: review. hymenoptera thorax = fusion of thorax and mesosoma/metasoma subset: uberon_slim synonym: "adult mesothoracic wing" RELATED [] synonym: "adult metathoracic wing" RELATED [] synonym: "thoracic wing" RELATED [] synonym: "wing" BROAD SENSU [FBbt:00004729] synonym: "thorax wing" RELATED [OBOL:automatic] synonym: "wing of thorax" RELATED [OBOL:automatic] xref: FBbt:00004729 ! wing xref: HAO:0001089 ! wing xref: TGMA:0000196 ! adult mesothoracic wing is_a: UBERON:0000023 ! wing intersection_of: UBERON:0000023 ! wing intersection_of: develops_from UBERON:0000939 ! imaginal disc [Term] id: UBERON:0000985 name: axillary vein def: "In human anatomy, the axillary vein is a large blood vessel that conveys blood from the lateral aspect of the thorax, axilla (armpit) and upper limb toward the heart. There is one axillary vein on each side of the body. Its origin is at the lower margin of the teres major muscle and a continuation of the brachial vein. Its tributaries include the basilic vein and cephalic vein, which are both superficial veins. It terminates at the lateral margin of the first rib, at which it becomes the subclavian vein. It is accompanied along its course by a similarly named artery, the axillary artery. [WP,unvetted]." [Wikipedia:Axillary_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "subcostal vein" RELATED [] xref: FMA:13329 ! Axillary vein xref: GAID:527 ! axillary vein xref: galen:AxillaryVein xref: MA:0002084 ! axillary vein xref: ncithesaurus:Axillary_Vein ! Axillary Vein xref: OpenCyc:Mx4rwLSHK5wpEbGdrcN5Y29ycA ! axillary vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Gray576.png/200px-Gray576.png xref: EMAPA:18758 ! axillary vein xref: MESH:A07.231.908.077 ! axillary vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0001467 ! shoulder xref: SCTID:181389002 ! Entire axillary vein synonym: "vena axillaris" RELATED LATIN [Wikipedia:Axillary_vein] xref: http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray576.png xref: UMLS:C0004456 [Term] id: UBERON:0000987 name: haltere def: "The capitate stalk on both sides of the thorax having developed from the dorsal metathoracic wing-buds, it is freely movable and capable of vibration, representing the hind wing of Diptera; used for flight balance." [FB:gg, ISBN:3110148986, Wikipedia:Haltere] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology subset: uberon_slim synonym: "balancer organ" RELATED [] xref: EFO:0000886 ! haltere xref: FBbt:00004783 ! haltere xref: MAT:0000203 ! haltere xref: MIAA:0000203 ! haltere xref: OpenCyc:Mx4rwL1JcJwpEbGdrcN5Y29ycA ! halter is_a: UBERON:0000026 ! appendage relationship: develops_from UBERON:0000939 ! imaginal disc relationship: part_of UBERON:0000914 ! organismal segment [Term] id: UBERON:0000988 name: pons def: "Brainstrem structure that has as its parts the pontine tegmentum and basal part of pons[FMA]." [Wikipedia:Pons, FMA:67943] comment: The pons is not present in zebrafish. In this ontology we currently have some structures which are applicable to zebrafish appearing as parts of the pons. Currently we only include the weaker dubious_for_taxon relationship ubtil this is resolved subset: uberon_slim synonym: "pons of Varolius" EXACT [] synonym: "pons Varolii" EXACT [ncithesaurus:Pons_Varolii] xref: BTO:0001101 xref: FMA:67943 ! Pons xref: GAID:578 ! pon xref: VHOG:0001176 ! pons xref: MA:0000204 ! pons xref: MAT:0000115 ! pons xref: MIAA:0000115 ! pons xref: NIF_GrossAnatomy:birnlex_733 ! Pons xref: EFO:0001394 ! pons xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/36/Gray768.png/200px-Gray768.png xref: MESH:A08.186.211.132.810.428.600 ! pon xref: EMAPA:17563 ! pons xref: EV:0100253 ! pons xref: ABA:P ! Pons xref: BM:Pons ! pons is_a: UBERON:0002680 ! regional part of metencephalon relationship: part_of UBERON:0001895 ! metencephalon relationship: part_of UBERON:0002298 ! brainstem relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: dubious_for_taxon NCBITaxon:7955 ! Danio rerio relationship: spatially_disjoint_from UBERON:0001896 {source="ABA"} ! medulla oblongata xref: SCTID:279103004 ! Entire pons xref: EHDAA2:0004394 ! pons xref: ncithesaurus:Pons_Varolii ! Pons Varolii xref: http://upload.wikimedia.org/wikipedia/commons/3/36/Gray768.png property_value: external_definition "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001176", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/pons", source="http://bgee.unil.ch/"} property_value: homology_notes "During the embryonic development of birds and mammals, neuroblasts migrate from the cerebellum into the ventral part of the rhombencephalon and differentiate into pontine and other nuclei, which relay information from between the cerebrum and cerebellum, and a conspicuous band of transverse fibers. This region is known as the pons. A pons does not differentiate in reptiles and anamniotes (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001176", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.474", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0032639 [Term] id: UBERON:0008811 ! intromittent organ name: intromittent organ def: "an external organ of a male organism that is specialized to deliver sperm during copulation. Intromittent organs are found most often in terrestrial species, as most aquatic species fertilize their eggs externally, although there are exceptions[WP]." [Wikipedia:Intromittent_organ] subset: grouping_class comment: this is a broad grouping class connecting a number of different analagous organs by their function. We place the insect aedeagus here rather than penis, although this is somewhat arbitrary given the broadness of the current definition synonym: "aedeagus" NARROW SENSU [FBbt:00004850] synonym: "penis" NARROW [] xref: AAO:0010255 ! intromittent organ xref: TGMA:0000585 ! aedeagus xref: HAO:0000091 ! aedeagus xref: FBbt:00004850 ! aedeagus is_a: UBERON:0003133 ! reproductive organ relationship: part_of UBERON:0000079 ! male reproductive system relationship: has_function_in GO:0007620 ! copulation subset: organ_slim xref: TAO:0002036 ! intromittent organ property_value: external_definition "Surface structure that is an external structure of a male organism through which sperm is transferred to a female organism during mating.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002036", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0010516 ! clasper name: clasper def: "a male anatomical structure found some groups of animals, used in mating. Male cartilaginous fish have claspers formed from the posterior portion of their pelvic fin which serve as intromittent organs used to channel semen into the female's cloaca during mating. The act of mating in some fish including sharks usually includes one of the claspers raised to allow water into the siphon through a specific orifice. The clasper is then inserted into the vagina, where it opens like an umbrella to anchor its position. The siphon then begins to contract expelling water and sperm. Male chimaeras have cephalic claspers on their heads, which are thought to aid in holding the female during mating" [Wikipedia:clasper] comment: Taxon notes: the term is also used for insect claspers, but we reserve it for the elasmobranchii structure is_a: UBERON:0008811 {source="Wikipedia"} ! intromittent organ [Term] id: UBERON:0010517 name: cephalic clasper def: "A mace-like spiny-headed rod found on the mid-dorsal surface of heads of male Holocephali. Thought to aid in holding the female during copulation." [Wikipedia:Chimaera#Description_and_tastes, http://fishbase.org/glossary/Glossary.php?q=tenaculum, http://www.fishbase.org/glossary/Glossary.php?q=cephalic+clasper] synonym: "tenaculum" RELATED [] synonym: "anterior tenaculum" RELATED [] synonym: "head clasper" RELATED [http://www.fishbase.org/glossary/Glossary.php?q=head+clasper] intersection_of: UBERON:0010516 ! clasper intersection_of: part_of UBERON:0000033 ! head relationship: in_median_plane_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:7864 ! Chimaeriformes [Term] id: UBERON:0010518 name: pelvic fin clasper def: "The rod-like extension of the medial portion of the pelvic fin in male Elasmobranchii and Holocephali. Claspers are used as intromittent organs (not in clasping), the grooves on their facing surfaces together forming a tube for the transmission of sperm when the claspers are held together. The anterior proximal opening is called the apopyle, the posterior distal opening the rhipidion" [http://fishbase.org/Glossary/Glossary.php?q=clasper] synonym: "clapser" RELATED [] synonym: "myxopterygium" EXACT [http://fishbase.org/Glossary/Glossary.php?q=clasper] intersection_of: UBERON:0010516 ! clasper intersection_of: part_of UBERON:0000152 ! pelvic fin [Term] id: UBERON:0000989 name: penis def: "The penis (plural penises, penes) is an external sexual organ of certain biologically male organisms, in both vertebrates and invertebrates. The penis is a reproductive organ, technically an intromittent organ, and for placental mammals, additionally serves as the external organ of urination. The penis is generally found on mammals and reptiles. [WP,unvetted]." [Wikipedia:Penis] comment: Most male birds (e.g., roosters and turkeys) have a cloaca (also present on the female), but not a penis. Among bird species with a penis are paleognathes (tinamous and ratites), Anatidae (ducks, geese and swans), and a very few other species (such as flamingoes). A bird penis is different in structure from mammal penises, being an erectile expansion of the cloacal wall and being erected by lymph, not blood. It is usually partially feathered and in some species features spines and brush-like filaments, and in flaccid state curls up inside the cloaca[WP] subset: uberon_slim synonym: "phallus" RELATED [] xref: BTO:0000405 xref: FMA:9707 ! Penis xref: GAID:389 ! penis xref: VHOG:0000727 ! penis xref: MA:0000408 ! penis xref: MAT:0000186 ! penis xref: MIAA:0000186 ! penis xref: ncithesaurus:Penis xref: OpenCyc:Mx4rvVjkCZwpEbGdrcN5Y29ycA xref: EFO:0000987 ! penis xref: EHDAA:9380 ! penis xref: galen:Penis ! penis xref: OpenCyc:Mx4rvVjkCZwpEbGdrcN5Y29ycA ! penis xref: EHDAA2:0001433 ! penis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/87/Labelled_flaccid_penis.jpg/200px-Labelled_flaccid_penis.jpg xref: EMAPA:18682 ! penis xref: EMAPA:18996 ! penile region xref: MESH:A05.360.444.492 ! penis xref: EV:0100107 ! penis is_a: UBERON:0008811 {source="Wikipedia"} ! intromittent organ relationship: develops_from UBERON:0005876 {source="EHDAA2"} ! genital tubercle relationship: develops_from UBERON:0004876 {source="Wikipedia"} ! urogenital ridge xref: SCTID:265793009 ! Entire penis subset: organ_slim property_value: has_relational_adjective "penile" xsd:string property_value: has_relational_adjective "phallic" xsd:string xref: UMLS:C0030851 [Term] id: UBERON:0008812 name: hemipenis def: "one of a pair of intromittent organs of male squamates. Hemipenes are usually held inverted, within the body, and are everted for reproduction via erectile tissue like that in the human penis. Only one is used at a time, and some evidence indicates males alternate use between copulations. The hemipenis itself has a variety of shapes, depending on species. Often the hemipenis bears spines or hooks, in order to anchor the male within the female. Some species even have forked hemipenes (each hemipenis has two tips). Due to being everted and inverted, hemipenes do not have a completely enclosed channel for the conduction of sperm, but rather a seminal groove which seals as the erectile tissue expands" [Wikipedia:Hemipenis] synonym: "hemipenes" RELATED PLURAL [Wikipedia:Hemipenis] is_a: UBERON:0008811 {source="Wikipedia"} ! intromittent organ relationship: only_in_taxon NCBITaxon:8509 ! Squamata subset: organ_slim xref: SCTID:27265006 ! Hemipenis structure [Term] id: UBERON:0004122 name: genitourinary system synonym: "genitourinary tract" RELATED [] synonym: "GU tract" RELATED [] synonym: "urogenital system" EXACT [] synonym: "urogenital tract" RELATED [BTO:0003091] synonym: "Urogenitalsystem" RELATED [BTO:0003091] property_value: has_relational_adjective "urogenital" xsd:string property_value: has_relational_adjective "genitourinary" xsd:string xref: BILA:0000122 ! urogenital system xref: GAID:362 ! urogenital system xref: XAO:0000140 ! urogenital system xref: OpenCyc:Mx4rQRpVMgAKEdyHxgDggVfs8g ! genitourinary system xref: ncithesaurus:Genitourinary_System ! Genitourinary System xref: BTO:0003091 ! urogenital system xref: VHOG:0000286 ! urogenital system xref: EMAPA:16367 ! genitourinary system xref: AAO:0000624 ! urogenital system xref: MESH:A05 ! urogenital system xref: EHDAA:1013 ! urogenital system xref: EV:0100094 ! urogenital system xref: EFO:0003864 ! genitourinary system is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: has_part UBERON:0000990 ! reproductive system intersection_of: has_part UBERON:0001008 ! urinary system relationship: develops_from UBERON:0003064 {source="AAO"} ! intermediate mesoderm xref: galen:GenitoUrinarySystem xref: SCTID:278861008 ! Entire genitourinary system property_value: external_definition "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000624", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship type change: differentiates_from intermediate mesoderm (AAO:0010575) CHANGED TO: develops_from intermediate mesoderm (UBERON:0003064)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000624", date_retrieved="2012-06-20"} property_value: homology_notes "Kidneys and gonads (of vertebrates) develop from adjacent tissues, and after the excretory or urinary ducts have developed, the reproductive system usually taps into them or their derivatives.[well established][VHOG]" xsd:string {external_class="VHOG:0000286", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.633", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An anatomical system that has_part a reproductive system and has_part a excretory system." [OBOL:automatic] xref: UMLS:C0042066 [Term] id: UBERON:0000990 name: reproductive system def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] comment: Editor notes: consider splitting genitalia from reproductive system subset: uberon_slim subset: functional_classification subset: vertebrate_core synonym: "genital system" RELATED [] synonym: "animal reproductive system" RELATED [BTO:0000081] synonym: "Geschlechtsorgan" RELATED [BTO:0000081] synonym: "organa genitalia" RELATED [BTO:0000081] synonym: "reproductive tissue" RELATED [BTO:0000081] synonym: "genitalia" RELATED PLURAL [] xref: BILA:0000103 xref: BTO:0000081 xref: EHDAA:5923 ! reproductive system xref: FBbt:00004857 ! reproductive system xref: FMA:7160 ! Genital system xref: HAO:0000374 ! genitalia xref: HAO:0000895 ! reproductive system xref: VHOG:0000182 ! reproductive system xref: MA:0000326 ! reproductive system xref: MIAA:0000305 ! reproductive system xref: OpenCyc:Mx4rvVja4ZwpEbGdrcN5Y29ycA xref: TAO:0000632 ! reproductive system xref: WBbt:0005747 ! reproductive system xref: XAO:0000142 ! genital system xref: ZFA:0000632 ! reproductive system xref: ncithesaurus:Reproductive_System ! Reproductive System xref: EFO:0000809 ! animal reproductive system xref: GAID:363 ! genitalia xref: OpenCyc:Mx4rvVja4ZwpEbGdrcN5Y29ycA ! reproductive system xref: EHDAA2:0001603 ! reproductive system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/52/Penis.svg/200px-Penis.svg.png xref: EMAPA:17381 ! reproductive system (also: UBERON:0003133 'reproductive organ') xref: EV:0100100 ! reproductive system is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: has_function_in GO:0000003 ! reproduction disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system relationship: develops_from UBERON:0000926 ! mesoderm xref: AAO:0010258 ! reproductive system xref: SCTID:278875001 ! Entire reproductive system synonym: "systemata genitalia" RELATED LATIN [Wikipedia:Reproductive_system] xref: http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg property_value: external_definition "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010258", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "Arguably, one of the most important aspects of urbilaterian organogenesis would have been gonadogenesis, since Urbilateria must have successfully generated gametes and developed a strategy for extrusion and fertilization, in order to be the ancestor of all living Bilateria.[well established][VHOG]" xsd:string {external_class="VHOG:0000182", ontology="VHOG", source="PMID:21672850 Extavour CGM\, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across Bilateria. Integrative and Comparative Biology (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1261210 [Term] id: UBERON:0000991 name: gonad def: "Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [ISBN:0140512888, Wikipedia:Gonad, ZFA:0000413, ZFIN:curator] comment: FMA xref is a 'general anatomical term' subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "gonada" EXACT [] xref: AAO:0000213 ! gonad xref: BILA:0000123 xref: BTO:0000534 xref: FBbt:00004858 ! gonad xref: FMA:18250 ! Gonad xref: GAID:368 ! gonad xref: HAO:0000379 ! gonad xref: VHOG:0000397 ! gonad xref: MA:0002420 ! gonad xref: TAO:0000413 ! gonad xref: WBbt:0005175 ! gonad xref: XAO:0003146 ! gonad xref: ZFA:0000413 ! gonad xref: ncithesaurus:Gonad ! Gonad xref: OpenCyc:Mx4rwQvdiZwpEbGdrcN5Y29ycA ! gonad xref: MESH:A05.360.576 ! gonad xref: EMAPA:17383 ! gonad of reproductive system xref: EMAPA:16857 ! gonad of genitourinary system is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: has_part CL:0000586 ! germ cell relationship: part_of UBERON:0000990 ! reproductive system relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: site_of GO:0007276 ! gamete generation relationship: develops_from UBERON:0005564 ! gonad primordium xref: SCTID:304623008 ! Entire gonad subset: organ_slim property_value: external_definition "Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000213", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The part of the reproductive system that produces and releases eggs (ovary) or sperm (testis).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000413", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000397", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T\, Capel B\, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "gonadal" xsd:string xref: UMLS:C0018067 [Term] id: UBERON:0000992 name: female gonad def: "Ovum-producing female reproductive organ." [Wikipedia:Ovary] comment: Ovaries of some kind are found in the female reproductive system of many animals that employ sexual reproduction, including invertebrates. However, they develop in a very different way in most invertebrates than they do in vertebrates, and are not truly homologous. Many of the features found in human ovaries are common to all vertebrates, including the presence of follicular cells, tunica albuginea, and so on. However, many species produce a far greater number of eggs during their lifetime than do humans, so that, in fish and amphibians, there may be hundreds, or even millions of fertile eggs present in the ovary at any given time. In these species, fresh eggs may be developing from the germinal epithelium throughout life. Corpora lutea are found only in mammals, and in some elasmobranch fish; in other species, the remnants of the follicle are quickly resorbed by the ovary. In birds, reptiles, and monotremes, the egg is relatively large, filling the follicle, and distorting the shape of the ovary at maturity. Amphibians and reptiles have no ovarian medulla; the central part of the ovary is a hollow, lymph-filled space. The ovary of teleosts is also often hollow, but in this case, the eggs are shed into the cavity, which opens into the oviduct. Although most normal female vertebrates have two ovaries, this is not the case in all species. In birds and platypuses, the right ovary never matures, so that only the left is functional. In some elasmobranchs, the reverse is true, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo[WP]. subset: uberon_slim subset: vertebrate_core synonym: "ovary" EXACT [] synonym: "ovum-producing ovary" EXACT SENSU [GO:0061039] synonym: "ovaries" RELATED PLURAL [] synonym: "female reproductive system gonad" EXACT [OBOL:automatic] synonym: "female reproductive system gonada" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "female organism genitalia gonad" EXACT [OBOL:automatic] synonym: "female organism genitalia gonada" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonad" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonada" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonad" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonada" EXACT [OBOL:automatic] synonym: "gonad of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonad of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonad of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonad of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "gonada of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonada of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonada of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonada of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "reproductive system of female organism gonad" EXACT [OBOL:automatic] synonym: "reproductive system of female organism gonada" EXACT [OBOL:automatic] xref: AAO:0000371 ! ovary xref: BILA:0000125 xref: BTO:0000975 xref: EHDAA:8124 ! ovary xref: FBbt:00004865 ! ovary xref: FMA:7209 ! Ovary xref: GAID:367 ! ovary xref: VHOG:0000251 ! ovary xref: MA:0000384 ! ovary xref: MIAA:0000125 ! ovary xref: ncithesaurus:Ovary xref: OpenCyc:Mx4rvVi9QJwpEbGdrcN5Y29ycA xref: TAO:0000403 ! ovary xref: XAO:0000258 ! ovary xref: ZFA:0000403 ! ovary xref: EHDAA2:0001360 ! ovary xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Female_anatomy.png/200px-Female_anatomy.png xref: EMAPA:17962 ! ovary xref: MESH:A05.360.319.114.630 ! ovary xref: EV:0100111 ! ovary intersection_of: UBERON:0000991 ! gonad intersection_of: part_of UBERON:0000474 ! female reproductive system relationship: develops_from UBERON:0009117 ! indifferent gonad relationship: only_in_taxon NCBITaxon:33208 ! Metazoa xref: SCTID:181464007 ! Entire ovary subset: organ_slim synonym: "ovarium" RELATED LATIN [Wikipedia:Ovary] xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray589.png property_value: external_definition "Either of paired female reproductive organs involved in production of ova and female sex hormones.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000371", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Female reproductive organ.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000403", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass gonad (TAO:0000413) CHANGED TO: develops_from gonad (UBERON:0000991)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000403", date_retrieved="2012-08-14"} property_value: homology_notes " (...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {external_class="VHOG:0000251", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM\, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007)\, DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B\, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0003975 {source="FMA-abduced-lr", gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! internal female genitalia property_value: has_relational_adjective "ovarian" xsd:string xref: EFO:0000973 ! animal ovary xref: UMLS:C0029939 [Term] id: UBERON:0000993 name: oviduct def: "passage from the ovaries to the outside of the body[Wikipedia:Oviduct]." [Wikipedia:Oviduct] comment: Usage notes: sometimes oviduct is used interchangeably with follaopian tube. Here they are different - the oviduct connects the gonad to the outside in a variety of animals. The mammal-class fallopian tube is derived from the mullerian duct and connects the gonads to the uterus. Taxon notes: in birds divided into infundibulum, magnum, isthmus, uterus, and vagina subset: uberon_slim subset: vertebrate_core synonym: "uterine tube" EXACT [] synonym: "tuba uterina" RELATED [BTO:0000980] synonym: "tuba uterinae" RELATED [BTO:0000980] xref: GAID:366 ! oviduct xref: BTO:0000980 ! oviduct xref: VHOG:0001136 ! oviduct xref: MAT:0000126 ! oviduct xref: MIAA:0000126 ! oviduct xref: TAO:0000560 ! oviduct xref: XAO:0003052 ! oviduct xref: ZFA:0000560 ! oviduct xref: EFO:0000974 ! oviduct (also: UBERON:0003889 'fallopian tube') xref: EMAPA:18984 ! oviduct xref: MESH:A13.706 ! oviduct is_a: UBERON:0000025 ! tube relationship: connects UBERON:0000992 ! female gonad relationship: connects UBERON:0013514 ! space surrounding organism relationship: part_of UBERON:0000474 ! female reproductive system xref: ncithesaurus:Oviduct ! Oviduct xref: AAO:0010533 ! oviduct property_value: external_definition "A passage through which ova leave the maternal body or pass to an organ communicating with the exterior of the body. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001136", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/oviduct", source="http://bgee.unil.ch/"} property_value: homology_notes "In all remaining vertebrates (i.e., coelacanths, lungfishes, amphibians, reptiles, birds, and mammals), the oviduct arises in ontogeny as a longitudinal, groovelike invagination of the coelomic epithelium on the lateral surface of the mesonephros.[well established][VHOG]" xsd:string {external_class="VHOG:0001136", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.687-688", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0029954 [Term] id: UBERON:0006835 name: arthropod oviduct def: "A tube that connects ovary to the uterus." [TADS:0000415] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology. Note that this is not even analagous to the class 'oviduct' in uberon (as the oviduct is the entire tube, from gonad to outside) xref: TADS:0000415 ! adult oviduct xref: FBbt:00004911 ! oviduct is_a: UBERON:0003914 {source="FBbt"} ! epithelial tube relationship: continuous_with UBERON:0000992 ! female gonad relationship: continuous_with UBERON:0006834 ! uterus or analog relationship: part_of UBERON:0000474 ! female reproductive system relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0003889 name: fallopian tube def: "Two very fine tubes lined with ciliated epithelia, leading from the ovaries of female mammals into the uterus, via the utero-tubal junction[WP]. Embryos have two pairs of ducts to let gametes out of the body; one pair (the Mullerian ducts) develops in females into the Fallopian tubes, uterus and vagina, while the other pair (the Wolffian ducts) develops in males into the epididymis and vas deferens." [Wikipedia:Fallopian_tube] comment: http://en.wikipedia.org/wiki/Talk:Fallopian_tube#Homology subset: uberon_slim synonym: "salpinx" BROAD [] synonym: "salpinges" BROAD PLURAL [] synonym: "fallopian tubes" RELATED [] synonym: "mammalian oviduct" EXACT [http://sourceforge.net/tracker/?func=detail&aid=3293337&group_id=36855&atid=440764] synonym: "uterine tube (sensu Mammalia)" EXACT [] synonym: "female paramesonephric duct" RELATED [EHDAA2:0000504] xref: FMA:18245 ! Uterine tube xref: GAID:365 ! fallopian tube xref: galen:FallopianTube xref: ncithesaurus:Fallopian_Tube xref: MA:0000385 ! oviduct xref: OpenCyc:Mx4rvViVeZwpEbGdrcN5Y29ycA xref: EFO:0000974 ! oviduct (also: UBERON:0000993 'oviduct') xref: OpenCyc:Mx4rvViVeZwpEbGdrcN5Y29ycA ! fallopian tube xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/68/Scheme_female_reproductive_system-en.svg/200px-Scheme_female_reproductive_system-en.svg.png xref: MESH:A05.360.319.114.373 ! fallopian tube xref: EV:0100112 ! uterine tube xref: EHDAA2:0000504 ! female paramesonephric duct intersection_of: UBERON:0000025 ! tube intersection_of: develops_from UBERON:0003890 ! mullerian duct intersection_of: part_of UBERON:0000993 ! oviduct relationship: part_of UBERON:0002355 ! pelvis relationship: connects UBERON:0000992 ! female gonad relationship: connects UBERON:0000995 ! uterus relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: SCTID:181463001 ! Entire fallopian tube synonym: "tuba uterina" RELATED LATIN [Wikipedia:Fallopian_tube] xref: http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg relationship: in_lateral_side_of UBERON:0003975 {source="FMA-abduced-lr"} ! internal female genitalia xref: UMLS:C0015560 [Term] id: UBERON:0011283 name: epoophoron def: "A remnant of the Mesonephric duct that can be found next to the ovary and fallopian tube." [Wikipedia:Epoophoron] synonym: "epoöphoron" RELATED [Wikipedia:Epoophoron] synonym: "epooephoron" RELATED [Wikipedia:Epoophoron] synonym: "organ of Rosenmüller" RELATED [Wikipedia:Epoophoron] synonym: "organ of rosenmueller" RELATED [Wikipedia:Epoophoron] synonym: "organ of rosenmuller" RELATED [Wikipedia:Epoophoron] synonym: "parovarium" RELATED [Wikipedia:Epoophoron] synonym: "organ of Rosenmuller" EXACT [FMA:18691] is_a: UBERON:0006590 {source="FMA"} ! vestigial embryonic structure relationship: part_of UBERON:0000474 ! female reproductive system relationship: develops_from UBERON:0003074 {source="Wikipedia"} ! mesonephric duct relationship: sexually_homologous_to UBERON:0001301 {source="Wikipedia"} ! epididymis xref: FMA:18691 ! epoophoron [Term] id: UBERON:0013248 name: paradidymis def: "A small collection of convoluted tubules, situated in front of the lower part of the cord above the head of the epididymis. These tubes are lined with columnar ciliated epithelium, and probably represent the remains of a part of the Wolffian body but are functionless and vestigial. The Wolffian body operates as a kidney (metanephros) in fishes and amphibians, but the corresponding tissue is co-opted to form parts of the male reproductive system in other classes of vertebrate. The paradidymis represents a remnant of an unused, atrophied part of the Wolffian body[WP,modified]." [Wikipedia:Paradidymis] is_a: UBERON:0003914 ! epithelial tube relationship: develops_from UBERON:0000083 {source="Wikipedia"} ! mesonephric tubule relationship: part_of UBERON:0000079 ! male reproductive system synonym: "organ of Giraldés" EXACT [] synonym: "organ of Giraldes" EXACT [FMA:74055] synonym: "Waldeyer's organ" EXACT [FMA:74055] xref: FMA:74055 ! paradidymis xref: SCTID:279643005 ! Entire paradidymis [Term] id: UBERON:0013249 name: paroophoron def: "A collection of a few scattered rudimentary tubules child, situated in the broad ligament between the epoophoron and the uterus." [Wikipedia:Paroophoron] synonym: "paroöphoron" RELATED [Wikipedia:Paroophoron] synonym: "parooephoron" RELATED [Wikipedia:Paroophoron] is_a: UBERON:0003914 ! epithelial tube relationship: part_of UBERON:0000474 ! female reproductive system relationship: develops_from UBERON:0000083 {source="Wikipedia"} ! mesonephric tubule synonym: "Kobelt's tubules" EXACT [FMA:18692] is_a: UBERON:0006590 {source="FMA"} ! vestigial embryonic structure xref: FMA:18692 ! paroophoron [Term] id: UBERON:0002247 name: uterine horn def: "The uterine horns are the points where the uterus and the fallopian tubes meet. It is one of the points of attachment for the round ligament of uterus (the other being the mons pubis). The uterine horns are far more prominent in other animals than they are in humans[WP,unvetted]." [Wikipedia:Uterine_horns] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:77053 ! Uterine horn xref: MA:0000393 ! uterine horn xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/27/Illu_female_pelvis.jpg/200px-Illu_female_pelvis.jpg xref: BTO:0004235 ! uterine horn xref: EMAPA:18985 ! uterine horn is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000995 {source="MA"} ! uterus relationship: connected_to UBERON:0003889 ! fallopian tube xref: SCTID:245480007 ! Entire horn of uterus xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Illu_female_pelvis.jpg relationship: in_lateral_side_of UBERON:0000995 ! uterus [Term] id: UBERON:0003890 alt_id: UBERON:0005318 name: Mullerian duct def: "paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]." [Wikipedia:Paramesonephric_duct, http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html, GO:0061205] comment: Development notes: Sertoli cells secrete anti-Mullerian hormone (AMH) inducing the demise of this duct synonym: "paramesonephric duct" EXACT [EMAPA:27665] synonym: "Müllerian duct" EXACT [] synonym: "Muellerian duct" EXACT [] synonym: "ductus paramesonephricus" EXACT [] synonym: "early paramesonephric duct" NARROW [EHDAA2:0004048] xref: GAID:1309 ! mullerian duct xref: XAO:0000330 ! Mullerian duct xref: ncithesaurus:Mullerian_Duct ! Mullerian Duct xref: VHOG:0001199 ! paramesonephric duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Gray1109.png/200px-Gray1109.png xref: MESH:A16.254.570 ! mullerian duct xref: EMAPA:27665 ! paramesonephric duct xref: RETIRED_EHDAA2:0001399 ! paramesonephric ducts xref: EHDAA2:0004048 ! early paramesonephric duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0000922 ! embryo relationship: in_lateral_side_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm xref: AAO:0010141 ! Mullerian duct xref: SCTID:308802006 ! Entire paramesonephric duct xref: http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png property_value: external_definition "Transient developmental organ which gives rise to oviducts in female (documented to persist in some male frogs).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010141", date_retrieved="2012-06-20", source="AAO:RED"} property_value: external_definition "Either of the paired embryonic ducts developing into the uterine tubes, uterus, and vagina in the female and becoming largely obliterated in the male. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001199", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/paramesonephric+duct", source="http://bgee.unil.ch/"} property_value: homology_notes "In females, the archinephric (mesonephric) ducts tend to function only within the urinary systems. The muellerian duct arises embryologically next to the archinephric (wolffian) duct. In males, the muellerian duct regresses if it appears at all, but in females, the muellerian ducts become the oviducts of the reproductive system.[well established][VHOG]" xsd:string {external_class="VHOG:0001199", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.559", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0026732 [Term] id: UBERON:0000994 name: spermathecum def: "an organ of the female reproductive tract in insects, some molluscs, oligochaeta worms and certain other invertebrates and vertebrates.[1] Its purpose is to receive and store sperm from the male, and can sometimes be the site of fertilization when the oocytes are ready.[2] Some species have multiple spermathecae, as seen in earthworms, where four pairs of spermathecae are present. One pair in 6,7,8 and 9 segments. They receive and store the spermatozoa of another earthworm during copulation.[3] They are lined with epithelium and are variable in shape; some are thin, heavily coiled tubes, others are vague outpocketings from the main reproductive tract. It is one of the many variations in sexual reproduction[WP]. an accordion-like tube that contains sperm and is the site of oocyte fertilization." [Wikipedia:Spermatheca] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "seminal receptacle" RELATED [] synonym: "spermatheca" RELATED PLURAL [] synonym: "receptaculum seminis" RELATED [BTO:0001273] xref: FBbt:00004921 ! spermathecum xref: MAT:0000168 ! spermathecum xref: MIAA:0000168 ! spermathecum xref: WBbt:0005319 ! spermatheca xref: EFO:0000977 ! spermathecum xref: BTO:0001273 ! spermatheca xref: HAO:0000945 ! spermatheca xref: TGMA:0000560 ! spermatheca is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0000991 ! gonad relationship: part_of UBERON:0000474 ! female reproductive system [Term] id: UBERON:0000995 name: uterus def: "a major female hormone-responsive reproductive sex organ of most mammals including humans. One end, the cervix, opens into the vagina, while the other is connected to one or both fallopian tubes, depending on the species. It is within the uterus that the fetus develops during gestation, usually developing completely in placental mammals such as humans and partially in marsupials such as kangaroos and opossums. Two uteruses usually form initially in a female fetus, and in placental mammals they may partially or completely fuse into a single uterus depending on the species. In many species with two uteruses, only one is functional. Humans and other higher primates such as chimpanzees, along with horses, usually have a single completely fused uterus, although in some individuals the uteruses may not have completely fused[WP]." [Wikipedia:Uterus] comment: Most animals that lay eggs, such as birds and reptiles, have an oviduct instead of a uterus. In monotremes, mammals which lay eggs and include the platypus, either the term uterus or oviduct is used to describe the same organ, but the egg does not develop a placenta within the mother and thus does not receive further nourishment after formation and fertilization. Marsupials have two uteruses, each of which connect to a lateral vagina and which both use a third, middle "vagina" which functions as the birth canal. Marsupial embryos form a choriovitelline "placenta" (which can be thought of as something between a monotreme egg and a "true" placenta), in which the egg's yolk sac supplies a large part of the embryo's nutrition but also attaches to the uterine wall and takes nutrients from the mother's bloodstream. subset: uberon_slim xref: FMA:17558 ! Uterus xref: GAID:172 ! uterus xref: VHOG:0001137 ! uterus xref: MA:0000389 ! uterus xref: MAT:0000127 ! uterus xref: MIAA:0000127 ! uterus xref: ncithesaurus:Uterus xref: OpenCyc:Mx4rvViojJwpEbGdrcN5Y29ycA xref: BTO:0001424 ! uterus xref: EFO:0000975 ! uterus xref: galen:Uterus ! uterus xref: OpenCyc:Mx4rvViojJwpEbGdrcN5Y29ycA ! uterus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Female_anatomy.png/200px-Female_anatomy.png xref: EMAPA:29915 ! uterus xref: MESH:A05.360.319.679 ! uterus xref: EV:0100113 ! uterus is_a: UBERON:0013515 {source="cjm"} ! zone of uterine tube relationship: part_of UBERON:0004175 ! internal genitalia relationship: transformation_of UBERON:0005795 ! embryonic uterus relationship: only_in_taxon NCBITaxon:32525 ! Theria xref: SCTID:181452004 ! Entire uterus subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/6/6a/Female_reproductive_system_lateral_nolabel.png property_value: external_definition "The hollow muscular organ in female mammals in which the blastocyst normally becomes embedded and in which the developing embryo and fetus is nourished. Its cavity opens into the vagina below and into a uterine tube on either side. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001137", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/uterus", source="http://bgee.unil.ch/"} property_value: homology_notes "An infundibulum, uterine tube, uterus, and vagina also differentiate along the oviducts of eutherian mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0001137", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.678", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "uterine" xsd:string xref: UMLS:C0042149 [Term] id: UBERON:0006834 ! uterus or analog name: uterus or analog def: "A subdivision of a the reproductive tract in a female organism that is the site of embryo development." [] subset: grouping_class synonym: "uterus" BROAD SENSU [FBbt:00004924] xref: FBbt:00004924 ! uterus xref: WBbt:0006760 ! uterus xref: TADS:0000421 ! adult uterus intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: site_of GO:0009790 ! embryo development relationship: part_of UBERON:0000474 ! female reproductive system relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: UBERON:0009098 name: gravid uterus def: "The uterus in pregnancy" [http://medical-dictionary.thefreedictionary.com/gravid+uterus] synonym: "womb" RELATED [] intersection_of: UBERON:0000995 ! uterus intersection_of: contains UBERON:0000922 ! embryo relationship: part_of UBERON:0009097 ! gravid organism relationship: site_of GO:0007565 ! female pregnancy xref: ncithesaurus:Gravid_Uterus ! Gravid Uterus xref: ncithesaurus:Pregnant_Uterus ! pregnant uterus xref: SCTID:362253003 ! Entire gravid uterus xref: UMLS:C1514389 [Term] id: UBERON:0005795 ! embryonic uterus name: embryonic uterus synonym: "fetal uterus" EXACT [FMA:72173] xref: FMA:72173 ! fetal uterus is_a: UBERON:0002050 ! embryonic structure xref: SCTID:255782009 ! Entire fetal uterus [Term] id: UBERON:0005796 name: duplex uterus def: "the duplex uterus is doubled, and is found in monotremes, marsupials, elephants and rodents" [http://www.shsu.edu/~bio_mlt/Chap14.html] is_a: UBERON:0000995 ! uterus [Term] id: UBERON:0005797 name: bipartite uterus def: "the bipartite uterus is y-shaped externally and divided internally (ungulates, carnivores)" [http://www.shsu.edu/~bio_mlt/Chap14.html] is_a: UBERON:0000995 ! uterus [Term] id: UBERON:0005798 name: bicornuate uterus def: "the bicornate uterus is y-shaped but has no internal partition (some ungulates, whales)" [http://www.shsu.edu/~bio_mlt/Chap14.html, Wikipedia:Bicornuate_uterus, Wikipedia:Uterus#Forms_in_mammals] synonym: "bicornate uterus" EXACT [] synonym: "uterus with two horns" EXACT [] is_a: UBERON:0000995 ! uterus [Term] id: UBERON:0005799 name: simplex uterus def: "the simplex uterus has only one uterine chamber (primates)" [http://www.shsu.edu/~bio_mlt/Chap14.html] is_a: UBERON:0000995 ! uterus [Term] id: UBERON:0006955 name: uterine epithelium synonym: "uterus epithelium" RELATED [BTO:0003082] xref: BTO:0003082 ! uterine epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000995 ! uterus def: "An epithelium that is part of a uterus." [OBOL:automatic] [Term] id: UBERON:0000996 name: vagina def: "a fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]." [Wikipedia:Vagina, FMA:19949] comment: Taxon notes (via vHOG): "The distal end of the oviducts differentiates as a vagina in Metatheria and Eutheria." Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective, Third Edition (2001) Orlando Fla.: Harcourt College Publishers, p.688 subset: uberon_slim synonym: "vaginae" RELATED PLURAL [] synonym: "distal oviductal region" RELATED [] synonym: "distal portion of oviduct" RELATED [] xref: BTO:0000243 xref: FMA:19949 ! Vagina xref: GAID:381 ! vagina xref: VHOG:0001138 ! vagina xref: MA:0000394 ! vagina xref: MAT:0000128 ! vagina xref: MIAA:0000128 ! vagina xref: ncithesaurus:Vagina xref: OpenCyc:Mx4rvVj1B5wpEbGdrcN5Y29ycA xref: EFO:0000976 ! vagina xref: galen:Vagina ! vagina xref: OpenCyc:Mx4rvVj1B5wpEbGdrcN5Y29ycA ! vagina xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a4/Vaginal_opening_-_english_description.jpg/200px-Vaginal_opening_-_english_description.jpg xref: EMAPA:18986 ! vagina xref: MESH:A05.360.319.779 ! vagina xref: EV:0100117 ! vagina is_a: UBERON:0013515 {source="cjm"} ! zone of uterine tube relationship: part_of UBERON:0003975 {source="FMA"} ! internal female genitalia relationship: develops_from UBERON:0000164 {source="Wikipedia"} ! primitive urogenital sinus xref: SCTID:181441005 ! Entire vagina xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/Illu_repdt_female.jpg property_value: external_definition "The genital canal in the female, leading from the opening of the vulva to the cervix of the uterus. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001138", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/vagina", source="http://bgee.unil.ch/"} property_value: external_definition "Organ with organ cavity which connects the cervical canal of uterus to the vestibule of vagina.[FMA]" xsd:string {ontology="FMA", external_class="FMA:19949", date_retrieved="2012-11-29"} property_value: homology_notes "The distal end of the oviducts differentiates as a vagina in Metatheria and Eutheria.[well established][VHOG]" xsd:string {external_class="VHOG:0001138", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.688", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "vaginal" xsd:string xref: UMLS:C0042232 [Term] id: UBERON:0013523 name: lateral vaginal canal def: "One of two lateral tracts connecting a uterus to a common median tract separated from the median vagina via ureters which prevent their fusion. Found in marsupials" [UBERON:cjm] synonym: "lateral vagina" EXACT [] synonym: "lateral vaginae" EXACT PLURAL [] intersection_of: UBERON:0000996 ! vagina intersection_of: in_lateral_side_of UBERON:0003975 ! internal female genitalia intersection_of: connected_to UBERON:0013524 ! median vagina relationship: only_in_taxon NCBITaxon:9263 {editor="cjm"} ! Metatheria relationship: channel_for UBERON:0001968 {notes="the lateral vaginae serve as transport for the sperm"} ! semen [Term] id: UBERON:0013524 name: median vaginal canal def: "A median canal in the reproductive system of marsupials that connects the uteri to a common tract, joining with the two lateral vaginas. Connects the uterine openings directly with the urogenital sinus" [UBERON:cjm] synonym: "midline birth canal" RELATED [] synonym: "median vagina" EXACT [] synonym: "central vagina" EXACT [] synonym: "central pseudovaginal canal" EXACT [] synonym: "median pseudovaginal canal" EXACT [] intersection_of: UBERON:0000996 ! vagina intersection_of: in_median_plane_of UBERON:0003975 ! internal female genitalia intersection_of: connected_to UBERON:0013523 ! lateral vagina relationship: only_in_taxon NCBITaxon:9263 {editor="cjm"} ! Metatheria relationship: channel_for UBERON:0000922 ! embryo [Term] id: UBERON:0000997 name: mammalian vulva def: "external genital organs of the female mammal[WP]." [Wikipedia:Vulva] comment: editor note: todo - add pudendum subset: uberon_slim synonym: "mammalian vulva" EXACT [] synonym: "skin of female pudendum" EXACT [] synonym: "skin of vulva" EXACT [] synonym: "vulva" EXACT [MA:0000395] synonym: "female pudendum" EXACT [FMA:20462] synonym: "pudendum femininum" EXACT LATIN [FMA:TA, FMA:20462] synonym: "puboperineal region" EXACT [FMA:20462] synonym: "female pudendum" EXACT [BTO:0003101] xref: BTO:0003101 ! female pudendum xref: FMA:20462 ! Vulva xref: GAID:383 ! vulva xref: VHOG:0001458 ! vulva xref: MA:0000395 ! vulva xref: MAT:0000169 ! vulva xref: MIAA:0000169 ! vulva xref: ncithesaurus:Vulva xref: OpenCyc:Mx4rvgAWeJwpEbGdrcN5Y29ycA xref: EFO:0000978 ! vulva xref: galen:Vulva ! vulva xref: OpenCyc:Mx4rvgAWeJwpEbGdrcN5Y29ycA ! vulva xref: MESH:A05.360.319.887 ! vulva xref: EV:0100118 ! vulva xref: SCTID:265796001 ! Entire vulva is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0005056 ! external female genitalia relationship: only_in_taxon NCBITaxon:40674 ! Mammalia synonym: "pudendum femininum" RELATED LATIN [Wikipedia:Vulva] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Female_unshaved_genitalia.jpg property_value: external_definition "The external genital organs of the female, including the labia majora, labia minora, clitoris, and vestibule of the vagina. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001458", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/vulva", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "vulval" xsd:string xref: UMLS:C0042993 [Term] id: UBERON:0005295 ! sex cord name: sex cord def: "Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female." [http://www.answers.com/topic/sex-cord, Wikipedia:Sex_cords] synonym: "primitive sex cord" RELATED [] synonym: "gonad cord" RELATED [] synonym: "gonadal cord" RELATED [] xref: RETIRED_EHDAA2:0001523 ! primitive sex cords is_a: UBERON:0005154 {source="EHDAA2"} ! epithelial cord relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0005294 ! genital ridge xref: EHDAA2:0004051 ! primitive sex cords (also: UBERON:0010141 'primitive sex cord of indifferent gonad') xref: SCTID:343823004 ! Entire primitive sex cord xref: ncithesaurus:Gonadal_Cord ! gonadal cord xref: UMLS:C1512242 [Term] id: UBERON:0010141 ! primitive sex cord of indifferent gonad name: primitive sex cord of indifferent gonad comment: Usage notes: note that this represents the indifferent structure. intersection_of: UBERON:0005295 ! sex cord intersection_of: part_of UBERON:0009117 {source="EHDAA2"} ! indifferent gonad relationship: develops_from UBERON:0005891 {source="EHDAA2"} ! coelomic epithelium synonym: "indifferent sex cord" EXACT [] synonym: "primitive sex cords" EXACT [EHDAA2:0004051] xref: EHDAA2:0004051 ! primitive sex cords (also: UBERON:0005295 'sex cord') def: "A sex cord that is part of a indifferent gonad." [OBOL:automatic] [Term] id: UBERON:0005296 ! ovary sex cord name: ovary sex cord def: "structures that develop from sex cords in the female. After further development they become the ovarian follicles." [Wikipedia:Cortical_cords] comment: TODO check secondary vs cortical vs ovary synonym: "ovary primitive sex cord" RELATED [] synonym: "cortical sex cord" RELATED [] synonym: "cortical cord" RELATED [] synonym: "secondary cord" RELATED [] synonym: "ovigerous cords" EXACT PLURAL [VHOG:0001339] synonym: "ovigerous cord" EXACT [] xref: EHDAA2:0001363 ! ovary primitive sex cords xref: EHDAA:8130 ! primitive sex cords xref: VHOG:0001339 ! ovigerous cords intersection_of: UBERON:0005295 ! sex cord intersection_of: part_of UBERON:0000992 ! female gonad relationship: develops_from UBERON:0010141 ! primitive sex cord of indifferent gonad xref: ncithesaurus:Cortical_Cord ! Cortical Cord xref: UMLS:C1511527 [Term] id: UBERON:0005297 ! testis sex cord name: testis sex cord def: "The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]." [Wikipedia:Testis_cords] comment: check primary vs testis synonym: "testis cord" EXACT [MP:0006424] synonym: "testis primitive sex cord" RELATED [] synonym: "primary sex cord" RELATED [] synonym: "testis primary sex cords" EXACT [EHDAA2:0002011] xref: EHDAA2:0002011 ! testis primary sex cords xref: EHDAA:8152 ! primitive sex cords xref: EMAPA:29098 ! primary sex cord xref: VHOG:0001321 ! testis cords intersection_of: UBERON:0005295 ! sex cord intersection_of: part_of UBERON:0000473 ! testis relationship: develops_from UBERON:0010141 ! primitive sex cord of indifferent gonad [Term] id: UBERON:0001343 ! seminiferous tubule of testis name: seminiferous tubule of testis def: "Seminiferous tubules are located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. The epithelium of the tubule consists of sustentacular or Sertoli cells, which are tall, columnar type cells that line the tubule. In between the Sertoli cells are spermatogenic cells, which differentiate through meiosis to sperm cells. There are two types: convoluted and straight. convuluted towards the lateral side and straight as the tubule comes medially to form ducts which will exit the testis. [WP,unvetted]." [Wikipedia:Seminiferous_tubule] subset: uberon_slim synonym: "tubuli seminiferi" EXACT [] synonym: "testis - seminiferous tubule" EXACT [] synonym: "seminiferous tubule" EXACT [] synonym: "seminiferous cord" EXACT [EMAPA:18685] xref: BTO:0001235 xref: FMA:19825 ! Seminiferous tubule of testis xref: GAID:400 ! seminiferous tubule xref: VHOG:0001363 ! seminiferous tubule xref: MA:0000412 ! seminiferous tubule xref: MAT:0000503 ! seminiferous tubule xref: XAO:0003088 ! seminiferous tubule xref: ncithesaurus:Seminiferous_Tubule ! Seminiferous Tubule xref: EFO:0001404 ! seminiferous tubules xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6a/Gray1145.png/200px-Gray1145.png xref: EMAPA:31476 ! Seminiferous tubule xref: MESH:A05.360.444.849.700 ! seminiferous tubule xref: EV:0100380 ! seminiferous tubule is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0000473 ! testicle relationship: site_of GO:0007126 ! meiosis relationship: site_of GO:0007283 ! spermatogenesis relationship: develops_from UBERON:0005297 {source="Wikipedia"} ! testis sex cord relationship: channel_for CL:0000019 ! sperm relationship: channels_into UBERON:0003959 ! rete testis xref: ncithesaurus:Seminiferous_Cord ! Seminiferous Cord xref: AAO:0010399 ! seminiferous tubule xref: SCTID:279614002 ! Entire seminiferous tubule xref: EMAPA:18685 ! seminiferous cord synonym: "tubuli seminiferi" RELATED LATIN [Wikipedia:Seminiferous_tubule] xref: http://upload.wikimedia.org/wikipedia/commons/4/49/Seminiferous_tubule_and_sperm_low_mag.jpg property_value: external_definition "Any of the coiled tubules located in the testes in which spermatozoa are produced.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010399", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "One of two or three twisted curved tubules in each lobule of the testis in which spermatogenesis occurs. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001363", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/SEMINIFEROUS+TUBULE", source="http://bgee.unil.ch/"} property_value: homology_notes "Frogs among amphibians and the amniotes have males with testes that are composed of seminiferous tubules, which differ from ampullae in being long, highly convoluted ductules.[well established][VHOG]" xsd:string {external_class="VHOG:0001363", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.688 and Figure 21-28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1519236 xref: UMLS:C0036630 [Term] id: UBERON:0004813 name: seminiferous tubule epithelium def: "The epithelium lining the seminiferous tubules composed of primary male germ cells (spermatogonia) and supporting sertoli cells. As spermatogenesis proceeds, the developing germ cells migrate toward the lumen. The adluminal compartment, the inner two thirds of the tubules, contains spermatocytes and the more advanced germ cells[GAID]." [Wikipedia:Germinal_epithelium_(male)] synonym: "epithelial tissue of seminiferous tubule" EXACT [OBOL:automatic] synonym: "epithelial tissue of seminiferous tubule of testis" EXACT [OBOL:automatic] synonym: "epithelium of seminiferous tubule" EXACT [OBOL:automatic] synonym: "epithelium of seminiferous tubule of testis" EXACT [OBOL:automatic] synonym: "seminiferous tubule epithelial tissue" EXACT [OBOL:automatic] synonym: "seminiferous epithelium" EXACT [BTO:0001811] synonym: "male germinal epithelium" EXACT [Wikipedia:Germinal_epithelium_(male)] synonym: "germinal epithelium (male)" EXACT [Wikipedia:Germinal_epithelium_(male)] synonym: "wall of seminiferous tubule" EXACT [Wikipedia:Germinal_epithelium_(male)] synonym: "testis germinal epithelium" EXACT [VHOG:0000631] xref: MA:0001748 ! seminiferous tubule epithelium xref: FMA:19885 ! Epithelium of seminiferous tubule of testis xref: BTO:0001811 ! seminiferous epithelium xref: GAID:401 ! seminiferous epithelium xref: VHOG:0000631 ! testis germinal epithelium xref: RETIRED_EHDAA2:0002009 ! testis germinal epithelium xref: MESH:A05.360.444.849.700.700 ! seminiferous epithelium xref: EHDAA:8148 ! germinal epithelium of testis is_a: UBERON:0001136 ! mesothelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001343 ! part_of seminiferous tubule of testis relationship: has_part CL:0000020 ! spermatogonium relationship: has_part CL:0000216 ! Sertoli cell xref: ncithesaurus:Seminiferous_Epithelium ! Seminiferous Epithelium xref: UMLS:C0036629 [Term] id: UBERON:0003959 ! rete testis name: rete testis def: "An anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the vasa efferentia[WP]." [MP:0006416, Wikipedia:Rete_testis] comment: Editors note: add more specific classification e.g. anastomosing network - consider FMA:3726 synonym: "Haller's rete" EXACT [FMA:19834] xref: FMA:19834 ! rete testis xref: EMAPA:18332 ! rete testis xref: GAID:399 ! rete testis xref: ncithesaurus:Rete_Testis ! Rete Testis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b5/Hodenschema.svg/200px-Hodenschema.svg.png xref: MESH:A05.360.444.849.600 ! rete testis is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0005051 ! mediastinum testis relationship: develops_from UBERON:0005297 {source="Wikipedia"} ! testis sex cord relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0001343 ! seminiferous tubule of testis relationship: channels_into UBERON:0006946 ! efferent duct xref: SCTID:279617009 ! Entire rete testis xref: http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg xref: UMLS:C0035278 [Term] id: UBERON:0006946 ! efferent duct name: efferent duct def: "The efferent ducts (or efferent ductules or ductuli efferentes) connect the rete testis with the initial section of the epididymis. The ductuli are unilaminar and composed of columnar ciliated and non-ciliated (absorptive) cells. The ciliated cells serve to stir the luminal fluids, possibly to help ensure homogeneous absorption of water from the fluid produced by the testis, which results in an increase in the concentration of luminal sperm. The epithelium is surrounded by a band of smooth muscle that helps to propel the sperm toward the epididymis." [Wikipedia:Efferent_ducts] comment: AO notes: Check EMAPA. Taxon notes: There are two basic designs for efferent ductule structure: a) multiple entries into the epididymis, as seen in most large mammals. In humans and other large mammals, there are approximately 15-20 efferent ducts, which also occupy nearly one third of the head of the epididymis. b) single entry, as seen in most small animals such as rodents, whereby the 3-6 ductules merge into a single small ductule prior to entering the epididymis synonym: "seminal duct" EXACT [] synonym: "efferent ductule" EXACT [Wikipedia:Efferent_ducts] synonym: "efferent ductule" EXACT [FMA:19081] synonym: "vasa efferentia" RELATED [AAO:0010532, Wikipedia:Efferent_ducts] synonym: "ductuli efferentes testis" RELATED [Wikipedia:Efferent_ducts] xref: MA:0000398 ! efferent duct xref: FMA:19081 ! efferent ductule xref: EMAPA:18993 ! efferent duct of seminal vesicle is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0000079 ! male reproductive system relationship: part_of UBERON:0006947 {source="FMA"} ! male genital duct relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0003959 ! rete testis relationship: channels_into UBERON:0001301 ! epididymis xref: ncithesaurus:Efferent_Ductule ! Efferent Duct xref: AAO:0010532 ! efferent ductules synonym: "ductuli efferentes testis" RELATED LATIN [Wikipedia:Efferent_ducts] xref: http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg property_value: external_definition "Any of a group ranging from one to twelve (varies in species) small seminal ducts per testis which transport sperm from the testes to the kidney.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010532", date_retrieved="2012-06-20", source="AAO:BJB"} xref: UMLS:C0228013 [Term] id: UBERON:0006948 name: efferent duct epithelium synonym: "epithelium of efferent ductule of testis" EXACT [FMA:19195] xref: MA:0001734 ! efferent duct epithelium xref: FMA:19195 ! epithelium of efferent ductule of testis intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006946 ! efferent duct def: "An epithelium that is part of a efferent duct." [OBOL:automatic] [Term] id: UBERON:0001301 ! epididymis name: epididymis def: "A narrow, tightly-coiled tube connecting the efferent ducts from the rear of each testicle to its vas deferens." [Wikipedia:Epididymis] comment: Taxon notes: A similar, but probably non-homologous, structure is found in cartilaginous fishes[WP]. Kardong has epididymis in elasmobranch.Structures notes: Typically divided into three main regions. In reptiles, there is an additional canal between the testis and the head of the epididymis, which receives the various efferent ducts. This is, however, absent in all birds and mammals. The epididymis is covered by a two layered pseudostratified epithelium. The epithelium is separated by a basement membrane from the connective tissue wall which has smooth muscle cells. subset: uberon_slim synonym: "epididymus" EXACT [] xref: BTO:0000408 xref: FMA:18255 ! Epididymis xref: GAID:397 ! epididymis xref: galen:Epididymis xref: VHOG:0001265 ! epididymis xref: MA:0000397 ! epididymis xref: MAT:0000130 ! epididymus xref: MIAA:0000130 ! epididymus xref: ncithesaurus:Epididymis xref: EFO:0000982 ! epididymus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Illu_testis_surface.jpg/200px-Illu_testis_surface.jpg xref: EMAPA:19290 ! epididymis xref: MESH:A05.360.444.849.286 ! epididymis xref: EV:0100103 ! epididymis is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0006947 {source="FMA"} ! male genital duct relationship: develops_from UBERON:0003074 {source="Wikipedia"} ! mesonephric duct relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0006946 ! efferent duct relationship: channels_into UBERON:0001000 ! vas deferens xref: SCTID:181432000 ! Entire epididymis xref: http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_testis_surface.jpg property_value: has_relational_adjective "epididymal" xsd:string xref: UMLS:C0014533 [Term] id: UBERON:0001000 ! vas deferens name: vas deferens def: "duct that transports sperm from the testis. In mammals this is from the epididymis." [Wikipedia:Vas_deferens] comment: Taxon notes (from WP): Most vertebrates have some form of duct to transfer the sperm from the testes to the urethra. In cartilaginous fish and amphibians, sperm is carried through the archinephric duct, which also partially helps to transport urine from the kidneys. In teleosts, there is a distinct sperm duct, separate from the ureters, and often called the vas deferens, although probably not truly homologous with that in humans. In cartilaginous fishes, the part of the archinephric duct closest to the testis is coiled up to form an epididymis. Below this are a number of small glands secreting components of the seminal fluid. The final portion of the duct also receives ducts from the kidneys in most species. In amniotes, however, the archinephric duct has become a true vas deferens, and is used only for conducting sperm, never urine. As in cartilaginous fish, the upper part of the duct forms the epididymis. In many species, the vas deferens ends in a small sac for storing sperm. The only vertebrates to lack any structure resembling a vas deferens are the primitive jawless fishes, which release sperm directly into the body cavity, and then into the surrounding water through a simple opening in the body wall. subset: uberon_slim subset: vertebrate_core synonym: "deferent duct" EXACT [] synonym: "ductus deferens" EXACT [Wikipedia:Vas_deferens] synonym: "sperm duct" RELATED [] synonym: "vas deferen" EXACT [] synonym: "vasa deferentia" RELATED [] xref: FMA:19234 ! Deferent duct xref: GAID:404 ! vas deferen xref: MA:0000413 ! vas deferens xref: MIAA:0000129 ! ductus deferens xref: ncithesaurus:Vas_Deferens ! Vas Deferens xref: BTO:0001427 ! vas deferens xref: EFO:0000981 ! ductus deferens xref: VHOG:0001135 ! ductus deferens xref: galen:VasDeferens ! vas deferens xref: OpenCyc:Mx4rvjv7bpwpEbGdrcN5Y29ycA ! vas deferens xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Male_anatomy_en.svg/200px-Male_anatomy_en.svg.png xref: EMAPA:18681 ! ductus deferens xref: MESH:A05.360.444.930 ! vas deferen xref: EV:0100105 ! vas deferens xref: SCTID:245467009 ! Entire vas deferens is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0006947 ! male genital duct relationship: part_of UBERON:0005352 {source="FMA"} ! spermatic cord relationship: channel_for UBERON:0001968 ! semen relationship: channels_from UBERON:0001301 ! epididymis relationship: channels_into UBERON:0000999 ! ejaculatory duct relationship: only_in_taxon NCBITaxon:32524 ! Amniota xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg property_value: homology_notes "The continuation of the archinephric duct, now called the deferent duct, extends caudally to the cloaca or to the part of the mammalian urethra that is derived from the cloaca.[well established][VHOG]" xsd:string {external_class="VHOG:0001135", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.670", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0042360 [Term] id: UBERON:0000999 ! ejaculatory duct name: ejaculatory duct def: "The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]." [Wikipedia:Ejaculatory_duct] subset: uberon_slim synonym: "ductus ejaculatorius" EXACT [BTO:0001580] synonym: "ductus ejaculatorii" EXACT PLURAL [BTO:0001580] xref: FMA:19325 ! Ejaculatory duct xref: GAID:388 ! ejaculatory duct xref: MAT:0000170 ! ejaculatory duct xref: MIAA:0000170 ! ejaculatory duct xref: ncithesaurus:Ejaculatory_Duct ! Ejaculatory Duct xref: BTO:0001580 ! ejaculatory duct xref: EFO:0000985 ! ejaculatory duct xref: OpenCyc:Mx4rwOt7MJwpEbGdrcN5Y29ycA ! ejaculatory duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/35/Male_anatomy.png/200px-Male_anatomy.png xref: EMAPA:19088 ! ejaculatory duct xref: MESH:A05.360.444.251 ! ejaculatory duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0000079 ! male reproductive system relationship: in_lateral_side_of UBERON:0000079 ! male reproductive system relationship: has_function_in GO:0042713 ! sperm ejaculation relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: channel_for UBERON:0010143 ! seminal vesicle fluid relationship: channel_for UBERON:0001968 ! semen relationship: channels_from UBERON:0001000 ! vas deferens relationship: channels_from UBERON:0000998 ! seminal vesicle relationship: channels_into UBERON:0000057 ! urethra xref: SCTID:279665005 ! Entire ejaculatory duct synonym: "ductus ejaculatorii" RELATED LATIN [Wikipedia:Ejaculatory_duct] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png xref: UMLS:C0013747 [Term] id: UBERON:0006953 name: ejaculatory duct epithelium def: "The ejaculatory duct epithelium is composed of cuboidal to columnar cells between or through which project the terminal parts of the ducts of the unicellular prostate glands." [PMID:1238970] comment: TODO: split off insect classes xref: BTO:0002618 ! ejaculatory duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000999 ! ejaculatory duct [Term] id: UBERON:0000998 name: seminal vesicle def: "Either of a pair of glandular pouches that lie one on either side of the male reproductive tract and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct." [BTO:0001234, Wikipedia:Seminal_vesicle] comment: Function notes: The seminal vesicles secrete a significant proportion of the fluid that ultimately becomes semen. Lipofuscin granules from dead epithelial cells give the secretion its yellowish color. About 50-70%[2] of the seminal fluid in humans originates from the seminal vesicles, but is not expelled in the first ejaculate fractions which are dominated by spermatozoa and zinc-rich prostatic fluid. subset: uberon_slim synonym: "gon_male_sves" RELATED [] synonym: "seminal gland" BROAD [] synonym: "vas efferens" RELATED [] synonym: "vesicul%c3%a6 seminales" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicula seminalis" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesiculae seminales" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular gland" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular glands" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular seminalis" RELATED [Wikipedia:Seminal_vesicle] synonym: "glandula seminalis" RELATED [BTO:0001234] synonym: "glandula vesiculosa" RELATED [BTO:0001234] synonym: "vesicula seminalis" RELATED [BTO:0001234] xref: BTO:0001234 xref: FMA:19386 ! Seminal vesicle xref: GAID:394 ! seminal vesicle xref: VHOG:0001379 ! seminal vesicle xref: MA:0000410 ! seminal vesicle xref: MAT:0000171 ! seminal vesicle xref: MIAA:0000171 ! seminal vesicle xref: ncithesaurus:Seminal_Vesicle ! Seminal Vesicle xref: EFO:0000986 ! seminal vesicle xref: OpenCyc:Mx4rwTtRpJwpEbGdrcN5Y29ycA ! seminal vesicle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Male_anatomy_en.svg/200px-Male_anatomy_en.svg.png xref: EMAPA:19180 ! seminal vesicle xref: MESH:A05.360.444.713 ! seminal vesicle xref: EV:0100106 ! seminal vesicle is_a: UBERON:0006868 ! seminal gland relationship: develops_from UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000473 ! testicle relationship: secretes UBERON:0010143 ! seminal vesicle fluid xref: AAO:0010788 ! seminal vesicle xref: SCTID:181434004 ! Entire seminal vesicle subset: organ_slim synonym: "vesiculæ seminales" RELATED LATIN [Wikipedia:Seminal_vesicle] xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg property_value: external_definition "Either of a pair of pouchlike glands situated on each side of the male urinary bladder that secrete seminal fluid and nourish and promote the movement of spermatozoa through the urethra. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001379", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/prominence", source="http://bgee.unil.ch/"} property_value: homology_notes " (In mammalian testis) Along the way (the sperm travel), three accessory sex glands, the seminal vesicle, prostate, and bulbourethral (Cowper's) gland, respectively, add their secretions as sperm move from the testes to the urethra.[well established][VHOG]" xsd:string {external_class="VHOG:0001379", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.556", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0036628 [Term] id: UBERON:0005903 name: duct of seminal vesicle def: "Each seminal vesicle consists of a single tube, coiled upon itself, and giving off several irregular cecal diverticula; the separate coils, as well as the diverticula, are connected together by fibrous tissue. When uncoiled, the tube is about the diameter of a quill, and varies in length from 10 to 15 cm.; it ends posteriorly in a cul-de-sac; its anterior extremity becomes constricted into a narrow straight duct called the excretory duct of seminal gland (or duct of the seminal vesicle), which joins with the corresponding ductus deferens to form the ejaculatory duct[WP]." [Wikipedia:Excretory_duct_of_seminal_gland] synonym: "ductus excretorius (vesicula seminalis)" EXACT [FMA:19473] synonym: "excretory duct of seminal gland" EXACT [FMA:19473] synonym: "seminal vesicle duct" EXACT [FMA:19473] synonym: "ductus excretorius glandulae vesiculosae" EXACT LATIN [FMA:TA, FMA:19473] xref: FMA:19473 ! duct of seminal vesicle xref: EMAPA:29282 ! duct of the seminal vesicle intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: channel_for UBERON:0010143 ! seminal vesicle fluid relationship: channels_into UBERON:0000999 ! ejaculatory duct xref: SCTID:279675008 ! Entire duct of seminal vesicle synonym: "ductus excretorius glandulae vesiculosae" RELATED LATIN [Wikipedia:Excretory_duct_of_seminal_gland] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Gray1160.png [Term] id: UBERON:0007194 name: vesicular gland def: "The vesicular gland is part of the male reproductive system. The vesicular gland contributes fluids, energy substrates, and buffers to semen. It can be found near the Coagulating gland, which also belongs to the reproductive system." [BTO:0003717] comment: todo - check this agaist seminal vesicle xref: BTO:0003717 ! vesicular gland xref: MA:0000405 ! vesicular gland is_a: UBERON:0010147 ! male accessory sex gland xref: ncithesaurus:Vesicular_Gland ! Vesicular Gland [Term] id: UBERON:0008807 name: coagulating gland is_a: UBERON:0010147 ! male accessory sex gland relationship: part_of UBERON:0002367 {source="EMAPA", not_supported_by="MA"} ! prostate gland xref: BTO:0000265 ! coagulating gland xref: EMAPA:29794 ! anterior prostate gland synonym: "anterior prostate gland" EXACT [EMAPA:29794] synonym: "prostate gland anterior lobe" RELATED [MA:0000402] xref: MA:0000402 ! coagulating gland xref: SCTID:78779004 ! Coagulating gland xref: ncithesaurus:Coagulating_Gland ! Coagulating Gland [Term] id: UBERON:0006868 name: seminal fluid secreting gland xref: FBbt:00004958 ! seminal vesicle xref: WBbt:0006870 ! seminal vesicle intersection_of: UBERON:0002530 ! gland intersection_of: secretes UBERON:0006530 ! seminal fluid relationship: part_of UBERON:0006947 ! male genital duct subset: organ_slim subset: grouping_class def: "A gland that secretes a seminal fluid." [OBOL:automatic] [Term] id: UBERON:0005904 name: duct of male reproductive system comment: groups the individual ducts in a variety of species subset: grouping_class intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0000079 ! male reproductive system def: "A duct that is part of a male reproductive system." [OBOL:automatic] [Term] id: UBERON:0006947 ! male genital duct alt_id: UBERON:0010140 name: male genital duct def: "A duct or series of ducts that transports sperm from the gonad. In mammals this is from the seminiferous tubules through rete testis, vas efferentia, epididymis, vas deferens, ejeculatory duct to the urethra." [UBERON:cjm] comment: Taxon notes: we use this as a generic grouping class for a number of taxa. AO notes: in FMA includes as parts: seminal vesicle, efferent ductule (vas efferentia), epididymis, deferent duct (vas deferens), ejaculatory duct xref: FMA:55678 ! male genital duct xref: ZFA:0001268 ! sperm duct synonym: "sperm duct" EXACT [ZFA:0001268] is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0004054 ! internal male genitalia relationship: channel_for UBERON:0001968 ! semen relationship: channels_from UBERON:0000473 ! testis subset: grouping_class xref: TAO:0001268 ! sperm duct synonym: "sperm ducts" EXACT PLURAL [TAO:0001268] relationship: in_lateral_side_of UBERON:0004054 {source="FMA-abduced-lr"} ! internal male genitalia [Term] id: UBERON:0001004 name: respiratory system def: "Functional system which consists of structures involved in respiration." [Wikipedia:Respiratory_system] subset: uberon_slim subset: functional_classification subset: vertebrate_core synonym: "apparatus respiratorius" EXACT [] synonym: "respiratory system" EXACT [] synonym: "apparatus respiratorius " RELATED [BTO:0000203] synonym: "Atmungssystem" RELATED [BTO:0000203] xref: AAO:0000541 ! respiratory_system xref: BTO:0000203 xref: EFO:0000804 ! respiratory system xref: EHDAA:2203 ! respiratory system xref: FMA:7158 ! Respiratory system xref: GAID:78 ! respiratory system xref: VHOG:0000202 ! respiratory system xref: MA:0000327 ! respiratory system xref: MAT:0000030 ! respiratory system xref: MIAA:0000030 ! respiratory system xref: OpenCyc:Mx4rvVjzFJwpEbGdrcN5Y29ycA xref: TAO:0000272 ! respiratory system xref: XAO:0000117 ! respiratory system xref: ZFA:0000272 ! respiratory system xref: ncithesaurus:Respiratory_System ! Respiratory System xref: OpenCyc:Mx4rvVjzFJwpEbGdrcN5Y29ycA ! respiratory system xref: EHDAA2:0001604 ! respiratory system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5e/Respiratory_system_complete_en.svg/200px-Respiratory_system_complete_en.svg.png xref: EMAPA:16727 ! respiratory system xref: MESH:A04 ! respiratory system xref: EV:0100036 ! respiratory system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha xref: SCTID:278197002 ! Entire respiratory system synonym: "systema respiratorium" RELATED LATIN [Wikipedia:Respiratory_system] xref: http://upload.wikimedia.org/wikipedia/commons/5/5e/Respiratory_system_complete_en.svg property_value: external_definition "The anatomical system in which the exchange of oxygen and carbon dioxide between the organism and its environment.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000541", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "There is no doubt that the primitive pattern of vertebrate air-breathing is the buccal pulse pump found in actinopterygian fishes.[well established][VHOG]" xsd:string {external_class="VHOG:0000202", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.599 and Figure 18-23", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0035237 [Term] id: UBERON:0000065 name: respiratory tract def: "anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts" [UBERON:cjm] xref: VHOG:0000393 ! respiratory tract xref: EHDAA:1568 ! respiratory tract xref: EHDAA:2219 ! respiratory tract xref: OpenCyc:Mx4rvvM--pwpEbGdrcN5Y29ycA ! respiratory tract xref: EHDAA2:0001606 ! respiratory tract xref: EMAPA:16737 ! respiratory tract is_a: UBERON:0001005 ! respiratory airway relationship: develops_from UBERON:0008947 ! respiratory primordium relationship: develops_from UBERON:0007026 {source="NBK10107"} ! primitive gut relationship: part_of UBERON:0001004 ! respiratory system xref: SCTID:361110005 ! Entire respiratory tract [Term] id: UBERON:0001005 name: respiratory airway def: "An airway through which respiratory air passes in organisms." [Wikipedia:Trachea] comment: This class generically groups trachea and analagous structures throughout metazoa. Consider renaming, as the term could be taken to mean lumen of tracheal system (e.g. in SNOMED) subset: uberon_slim subset: grouping_class is_a: UBERON:0003103 ! compound organ relationship: part_of UBERON:0001004 ! respiratory system xref: SCTID:361380005 ! Entire respiratory airway [Term] id: UBERON:0000117 ! respiratory tube name: respiratory tube def: "A tube in the respiratory tract." [GO:0030323] comment: Consider merging into respiratory tract is_a: UBERON:0000025 ! tube intersection_of: UBERON:0000025 ! tube intersection_of: part_of UBERON:0000065 ! respiratory tract synonym: "tracheobronchial tree segment" NARROW [FMA:12224] synonym: "segment of tracheobronchial tree" NARROW [FMA:12224] xref: FMA:12224 ! segment of tracheobronchial tree [Term] id: UBERON:0003126 name: trachea def: "The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]." [GO:0060438, Wikipedia:Vertebrate_trachea] comment: Taxon notes: in mouse 15-18 C-rings, 15-20 in human. [ISBN10:0123813611]. In birds, the trachea runs from the pharynx to the syrinx, from which the primary bronchi diverge. Swans have an unusually elongated trachea, part of which is coiled beneath the sternum; this may act as a resonator to amplify sound. In some birds, the cartilagenous rings are complete, and may even be ossified. In amphibians, the trachea is normally extremely short, and leads directly into the lungs, without clear primary bronchi. A longer trachea is, however found in some long-necked salamanders, and in caecilians. While there are irregular cartilagenous nodules on the amphibian trachea, these do not form the rings found in amniotes. The only vertebrate to have lungs, but no trachea, is Polypterus, in which the lungs arise directly from the pharynx. subset: uberon_slim subset: major_organ synonym: "cartilaginous trachea" EXACT [] synonym: "vertebrate trachea" EXACT SENSU [] synonym: "windpipe" EXACT [] synonym: "tracheal tubule" RELATED [BTO:0001388] xref: OpenCyc:Mx4rvViOX5wpEbGdrcN5Y29ycA xref: BTO:0001388 xref: EHDAA:3078 ! trachea xref: FMA:7394 ! Trachea xref: GAID:361 ! trachea xref: VHOG:0000371 ! trachea xref: MA:0000441 ! trachea xref: MAT:0000137 ! trachea xref: MIAA:0000137 ! trachea xref: XAO:0000118 ! trachea xref: EFO:0000935 ! trachea xref: ncithesaurus:Trachea ! Trachea xref: EFO:0000935 ! trachea xref: OpenCyc:Mx4rvViOX5wpEbGdrcN5Y29ycA ! windpipe xref: EHDAA2:0002066 ! trachea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Illu_conducting_passages.jpg/200px-Illu_conducting_passages.jpg xref: EMAPA:16853 ! trachea xref: MESH:A04.889 ! trachea xref: EV:0100040 ! trachea is_a: UBERON:0000117 ! respiratory tube relationship: part_of UBERON:0007196 ! tracheobronchial tree relationship: located_in UBERON:0002224 ! thoracic cavity relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium xref: AAO:0010140 ! trachea xref: SCTID:181213009 ! Entire trachea xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg property_value: external_definition "An elongated tube which carries air to and from the lungs.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010140", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The respiratory tube between the larynx and the bronchi. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000371", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In primitive fishes and most tetrapods, the lungs of adults are usually paired. They lie ventral to the digestive tract and are connected to the outside environment through the trachea.[well established][VHOG]" xsd:string {external_class="VHOG:0000371", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.409", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "tracheal" xsd:string xref: UMLS:C0040578 [Term] id: UBERON:0003604 name: trachea cartilage def: "The cartilages of the trachea (or tracheal rings) vary from sixteen to twenty in number: each forms an imperfect ring, which occupies the anterior two-thirds or so of the circumference of the trachea, being deficient behind, where the tube is completed by fibrous tissue and unstriped muscular fibers." [Wikipedia:Tracheal_rings] comment: Editor notes: check whether to classify as part of splanchoncranium synonym: "tracheal cartilage" EXACT [FMA:7434] synonym: "cartilage of windpipe" EXACT [OBOL:automatic] synonym: "cartilage of trachea" EXACT [OBOL:automatic] synonym: "cartilaginous trachea cartilage" EXACT [OBOL:automatic] synonym: "windpipe cartilage" EXACT [OBOL:automatic] synonym: "cartilago trachealis" EXACT [FMA:7434] synonym: "cartilage of the trachea" RELATED [Wikipedia:Tracheal_rings] synonym: "ring of the trachea" RELATED [Wikipedia:Tracheal_rings] synonym: "tracheal ring" RELATED [Wikipedia:Tracheal_rings] synonym: "trachea ring" RELATED [] synonym: "cartilaginous ring of trachea" EXACT [EMAPA:18699] xref: MA:0001857 ! trachea cartilage xref: ncithesaurus:Trachea_Cartilage ! Trachea Cartilage xref: FMA:7434 ! Tracheal cartilage xref: EMAPA:18699 ! cartilaginous ring of trachea intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0007267 ! trachea pre-cartilage rings xref: SCTID:278979006 ! Entire tracheal cartilage synonym: "cartilagines tracheales" RELATED LATIN [Wikipedia:Tracheal_rings] xref: http://upload.wikimedia.org/wikipedia/commons/5/56/Gray952.png xref: UMLS:C1710456 [Term] id: UBERON:0007267 ! trachea pre-cartilage rings name: trachea pre-cartilage rings xref: EHDAA2:0002070 ! trachea pre-cartilage rings xref: EHDAA:7082 ! pre-cartilage rings intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0009505 {source="EHDAA2"} ! associated mesenchyme of trachea def: "A pre-cartilage condensation that is part of a trachea." [OBOL:automatic] [Term] id: UBERON:0006833 name: lumen of trachea synonym: "tracheal lumen" EXACT [FMA:7469] synonym: "lumen of cartilaginous trachea" EXACT [OBOL:automatic] xref: FMA:7469 ! lumen of trachea intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0003126 ! trachea relationship: part_of UBERON:0003126 ! trachea xref: SCTID:197486000 ! Entire tracheal lumen def: "An anatomical space that surrounded_by a trachea." [OBOL:automatic] [Term] id: UBERON:0003127 ! open tracheal system trachea name: open tracheal system trachea def: "A trachea composed of composed of spiracles, tracheae, and tracheoles [Wikipedia]. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster." [GO:0007424, Wikipedia:Invertebrate_trachea] comment: TODO check if is_a epithelium subset: uberon_slim synonym: "invertebrate trachea" EXACT [] synonym: "trachea" BROAD SENSU [FBbt:00005043] xref: FBbt:00005043 ! trachea xref: SPD:0000434 ! trachea xref: TADS:0000315 ! adult trachea is_a: UBERON:0001005 ! respiratory airway relationship: has_part UBERON:0003914 ! epithelial tube relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0006832 name: lumen of open tracheal system trachea synonym: "tracheal lumen" BROAD SENSU [FBbt:00007410] xref: FBbt:00007410 ! tracheal lumen intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0003127 ! open tracheal system trachea relationship: part_of UBERON:0003127 ! open tracheal system trachea def: "An anatomical space that surrounded_by a open tracheal system trachea." [OBOL:automatic] [Term] id: UBERON:0005155 ! open tracheal system name: open tracheal system def: "An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster." [GO:0007424] subset: uberon_slim synonym: "open tracheal system" EXACT [] synonym: "invertebrate tracheal system" EXACT [] synonym: "tracheal system" BROAD SENSU [FBbt:00005024] xref: FBbt:00005024 ! tracheal system xref: SPD:0000427 ! tracheal system xref: TADS:0000043 ! adult respiratory system xref: BTO:0003870 ! insect tracheal system is_a: UBERON:0000467 ! anatomical system relationship: capable_of GO:0007585 ! respiratory gaseous exchange relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0001008 ! excretory system name: excretory system def: "The excretory system is the system of an organism that mainly performs the function of excretion, the bodily process of discharging wastes. It is responsible for the elimination of wastes produced by the processes that maintain homeostasis." [BILA:0000015, Wikipedia:Excretory_system] comment: In various sources such as Encyclopedia Britannica, the excretory and urinary systems are indeed the same system (see wikipedia talk page); we merge two BTO classes here subset: uberon_slim subset: vertebrate_core synonym: "urinary tract" EXACT [] synonym: "urinary system" EXACT [] synonym: "renal system" EXACT [GO:0001977] synonym: "renal/urinary system" RELATED [] synonym: "renal or urinary system" RELATED [EHDAA:5901] synonym: "systema urinaria" EXACT [FMA:7159] synonym: "urinary system" EXACT [] synonym: "systema urinarium" EXACT [BTO:0003092] xref: BILA:0000015 xref: EFO:0000803 ! renal system xref: FBbt:00005056 ! excretory system xref: FMA:7159 ! Urinary system xref: GAID:391 ! urinary system xref: VHOG:0000723 ! renal system xref: MAT:0000027 ! renal system xref: MIAA:0000027 ! renal system xref: ncithesaurus:Urinary_System xref: TAO:0000163 ! renal system xref: WBbt:0005736 ! excretory system xref: XAO:0000143 ! urinary system xref: ZFA:0000163 ! renal system xref: TADS:0000162 ! adult excretory system xref: BTO:0003092 ! urinary system xref: BTO:0001244 ! urinary tract xref: MA:0000325 ! renal/urinary system xref: EHDAA2:0001601 ! renal system xref: EMAPA:17366 ! urinary system xref: EHDAA:5901 ! renal or urinary system xref: EHDAA:5901 ! renal or urinary system xref: EV:0100095 ! urinary system xref: MESH:A05.810 ! urinary tract intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0007588 ! excretion disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system xref: AAO:0010257 ! urinary system xref: SCTID:362204003 ! Entire urinary system xref: galen:UrinaryTract ! urinary tract relationship: never_in_taxon NCBITaxon:110815 {source="Wikipedia"} ! Xenoturbella relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha property_value: external_definition "An anatomical system which consists of organs and tissues which produce, store, and excrete urine.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010257", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "Evolution of vertebrate renal anatomy appears quite conservative when compared, for example, to evolution of respiratory and cardiovascular systems in vertebrates. Major anatomical changes in vertebrates kidneys separate those of birds and mammals from kidneys of lower vertebrates. General increase in animal size from fish to mammals is reflected by an increase in total number of nephrons per kidney, rather than by constant change in tubular dimensions.[well established][VHOG]" xsd:string {external_class="VHOG:0000723", ontology="VHOG", source="ISBN:978-3540428541 Kapoor BG\, Bhavna Khanna\, Ichthyology Handbook (2004) p.406", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1508753 [Term] id: UBERON:0001009 ! circulatory system name: circulatory system def: "organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] comment: the cardiovascular system and the lymphatic system are parts of the circulatory system subset: uberon_slim xref: FBbt:00005057 ! circulatory system xref: OpenCyc:Mx4rvVjzG5wpEbGdrcN5Y29ycA ! circulatory system xref: VHOG:0001248 ! circulatory system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Circulatory_System_en.svg/200px-Circulatory_System_en.svg.png is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system relationship: never_in_taxon NCBITaxon:6157 ! Platyhelminthes relationship: never_in_taxon NCBITaxon:6073 ! Cnidaria relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha xref: AAO:0000959 ! circulatory system synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] xref: http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg property_value: external_definition "Anatomical system of ion binding, a pumping mechanism, and an efficient vascular system; consisting of the blood, heart, and blood and lymph vessels, respectively.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000959", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG]" xsd:string {external_class="VHOG:0001248", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.493", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009054 name: open circulatory system comment: The Open Circulatory System is a system in which fluid (called hemolymph) in a cavity called the hemocoel bathes the organs directly with oxygen and nutrients and there is no distinction between blood and interstitial fluid; this combined fluid is called hemolymph or haemolymph is_a: UBERON:0001009 {source="GO"} ! circulatory system [Term] id: UBERON:0009055 ! closed circulatory system name: closed circulatory system comment: Editor notes: consider merging with cardiovascular system? Taxon notes: The circulatory systems of all vertebrates, as well as of annelids (for example, earthworms) and cephalopods (squid and octopus) are closed, just as in humans. Still, the systems of fish, amphibians, reptiles, and birds show various stages of the evolution of the circulatory system is_a: UBERON:0001009 {source="GO"} ! circulatory system [Term] id: UBERON:0009056 name: two-pass circulatory system def: "A closed circulatory system in which blood passes twice through the heart to supply the body once." [Wikipedia:Double_circulatory_system, GO:0035905] is_a: UBERON:0009055 ! closed circulatory system [Term] id: UBERON:0009057 name: one-pass circulatory system def: "A closed circulatory system in which blood passes once through the heart to supply the body once." [GO:0035907] is_a: UBERON:0009055 ! closed circulatory system [Term] id: UBERON:0004535 ! cardiovascular system name: cardiovascular system def: "Anatomical system that has as its parts the heart and blood vessels." [BTO:0000088] comment: Usage notes: we treat cardiovascular as part of circulatory system, with the latter including other kinds of circulation, including lymph. subset: uberon_slim subset: vertebrate_core synonym: "CV system" RELATED [BTO:0000088] synonym: "Herz und Gefaesssystem" RELATED [BTO:0000088] xref: BILA:0000016 xref: BTO:0000088 xref: EFO:0000791 ! cardiovascular system xref: EHDAA:394 ! cardiovascular system xref: FMA:7161 ! Cardiovascular system xref: GAID:467 ! cardiovascular system xref: VHOG:0000302 ! cardiovascular system xref: MA:0000010 ! cardiovascular system xref: MAT:0000016 ! cardiovascular system xref: MIAA:0000016 ! cardiovascular system xref: OpenCyc:Mx4rvVjzG5wpEbGdrcN5Y29ycA xref: TAO:0000010 ! cardiovascular system xref: XAO:0000100 ! cardiovascular system xref: ZFA:0000010 ! cardiovascular system xref: XAO:0001010 ! circulatory system xref: ncithesaurus:Cardiovascular_System ! Cardiovascular System xref: EHDAA2:0000216 ! cardiovascular system (also: UBERON:0011695 'embryonic cardiovascular system') xref: EMAPA:16104 ! cardiovascular system of organ system xref: EMAPA:16370 ! cardiovascular system of extraembryonic component xref: MESH:A07 ! cardiovascular system xref: EV:0100017 ! cardiovascular system xref: WikipediaCategory:Cardiovascular_system intersection_of: UBERON:0000467 ! anatomical system intersection_of: part_of UBERON:0001009 ! circulatory system intersection_of: has_part UBERON:0001981 ! blood vessel intersection_of: has_part UBERON:0000948 ! heart xref: AAO:0011001 ! cardiovascular system xref: SCTID:278198007 ! Entire cardiovascular system property_value: homology_notes "The vessels of the cardiovascular system are as varied as the diverse organs they supply. However, these variations are based on modifications of a fundamental plan of organization common to vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000302", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.451", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0007226 [Term] id: UBERON:0011695 ! embryonic cardiovascular system name: embryonic cardiovascular system synonym: "fetal circulatory system" RELATED [] synonym: "embryonic circulatory system" RELATED [] synonym: "conceptus cardiovascular system" EXACT [] intersection_of: UBERON:0004535 ! cardiovascular system intersection_of: part_of UBERON:0004716 ! conceptus xref: EHDAA2:0000216 ! cardiovascular system (also: UBERON:0004535 'cardiovascular system') def: "A cardiovascular system that is part of a conceptus." [OBOL:automatic] [Term] id: UBERON:0007798 name: vascular system comment: in both MA and BTO, the arterial system and venous sytem are subtypes of the vascular system xref: MA:0002718 ! vascular system xref: BTO:0001085 ! vascular system is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0004535 {source="MA"} ! cardiovascular system xref: ncithesaurus:Vascular_System ! Vascular System xref: EHDAA2:0004520 ! vascular system xref: UMLS:C0489903 [Term] id: UBERON:0002465 name: lymphoid system alt_id: UBERON:0002096 def: "The lymphatic system in vertebrates is a network of conduits that carry a clear fluid called lymph. It also includes the lymphoid tissue through which the lymph travels. Lymphoid tissue is found in many organs, particularly the lymph nodes, and in the lymphoid follicles associated with the digestive system such as the tonsils. The system also includes all the structures dedicated to the circulation and production of lymphocytes, which includes the spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system (Wikipedia)." [Wikipedia:Lymphoid_system, https://sourceforge.net/tracker/?func=detail&aid=3153468&group_id=76834&atid=1205376] comment: We follow FMA and MA in distinguishing between lymphatic system and lymphoid system, with lymhoid tissue part of the non-lymphatic component, although these terms are often used interchangeably. We assume the ZFA term lymphatic tissue actually corresponds to the broader class (e.g. ZFA lymph node in the ZFA lymphatic system). See tracker for more comments. subset: uberon_slim subset: vertebrate_core synonym: "lymphatic system" NARROW [ZFA:0000385] synonym: "lymphatic circulatory system" RELATED [UBERON:cjm] xref: FMA:74594 ! Lymphoid system xref: VHOG:0000842 ! lymphatic system xref: MA:0002435 ! lymphoid system xref: EFO:0000870 ! lymphatic system (also: UBERON:0006558 'lymphatic part of lymphoid system') xref: EHDAA:8677 ! lymphatic system xref: GAID:931 ! lymphatic system xref: VHOG:0000842 ! lymphatic system xref: MAT:0000197 ! lymphatic system xref: MIAA:0000197 ! lymphatic system xref: ZFA:0000385 ! lymphatic system xref: XAO:0003199 ! lymphatic system xref: ncithesaurus:Lymphatic_System ! Lymphatic System xref: OpenCyc:Mx4rwQAKT5wpEbGdrcN5Y29ycA ! lymphatic system xref: EHDAA2:0001043 ! lymphatic system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/36/Illu_capillary_microcirculation.jpg/200px-Illu_capillary_microcirculation.jpg is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0002405 ! immune system relationship: part_of UBERON:0002193 ! hemolymphoid system xref: SCTID:362589007 ! Entire lymphoid system xref: TAO:0000385 ! lymphatic system synonym: "systema lymphoideum" RELATED LATIN [Wikipedia:Lymphoid_system] xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/TE-Lymphatic_system_diagram.svg property_value: external_definition "Part of the circulatory system which consists of a series of vessels which collect blood (exclusive of erythrocytes) which seep through capillary walls and return it to the veins.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010522", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "Tetrapods have evolved distinct lymphatic systems, in which lymphatic capillaries help drain most of the tissues of the body.[well established][VHOG]" xsd:string {external_class="VHOG:0000842", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.627", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0024235 property_value: has_relational_adjective "lymphoid" xsd:string [Term] id: UBERON:0006558 name: lymphatic part of lymphoid system def: "." [Wikipedia:Lymphatic_system] comment: AO notes: in FMA this is part of the cardiovascular system, but here we treat the CV system as a separate component of the circulatory system from the lymphatic system synonym: "lymphatic tree system" EXACT [FMA:7162] synonym: "lymphatic system" EXACT [MA:0002435, FMA:7162] xref: FMA:7162 ! Lymphatic system xref: EFO:0000870 ! lymphatic system (also: UBERON:0002465 'lymphoid system') xref: MA:0002961 ! lymphatic system xref: EMAPA:18248 ! lymphatic system xref: MESH:A15.382.520 ! lymphatic system is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001009 ! circulatory system relationship: part_of UBERON:0002465 ! lymphoid system relationship: part_of UBERON:0007798 {source="MA"} ! vascular system xref: AAO:0010522 ! lymphatic system xref: SCTID:362597000 ! Entire lymphatic system property_value: external_definition "Part of the circulatory system which consists of a series of vessels which collect blood (exclusive of erythrocytes) which seep through capillary walls and return it to the veins.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010522", date_retrieved="2012-06-20", source="AAO:BJB"} xref: VHOG:0001761 ! lymphatic system synonym: "lymporeticular system" RELATED [VHOG:0001761] property_value: has_relational_adjective "lymporeticular" xsd:string [Term] id: UBERON:0006561 name: non-lymphatic part of lymphoid system synonym: "non-lymphatic lymphoid system" EXACT [FMA:74623] xref: FMA:74623 ! Non-lymphatic lymphoid system is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0002465 ! lymphoid system [Term] id: UBERON:0002193 name: hemolymphoid system def: "Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs." [] synonym: "haemolymphoid system" RELATED [] synonym: "hematolymphoid system" EXACT [] synonym: "lymphomyeloid complex" EXACT [] xref: FMA:74562 ! Hemolymphoid system xref: MA:0000013 ! hemolymphoid system xref: EHDAA2:0004615 ! hemolymphoid system xref: EMAPA:18534 ! haemolymphoid system of gland of organ system xref: EMAPA:18765 ! haemolymphoid system of organ system is_a: UBERON:0000467 {source="MA"} ! anatomical system [Term] id: UBERON:0002390 name: hematopoietic system def: "The tissues concerned in production of the blood, including the bone marrow, liver, lymph nodes, spleen, and thymus[BTO]. Anatomical system that consists of the blood and blood forming tissues. The bodily system of organs and tissues, primarily the bone marrow, spleen, tonsils, and lymph nodes, involved in the production of blood[FD]." [http://www.thefreedictionary.com/hematopoietic+system, BTO:0000570, OMD:haematological, Wikipedia:Hematopoietic_system] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "haematological system" EXACT [] synonym: "haematopoietic system" RELATED [] synonym: "haemopoietic system" EXACT [] synonym: "hematological system" RELATED [] synonym: "hematolymphoid system" RELATED [] synonym: "hemopoietic system" RELATED [] synonym: "organa haemopoietica" EXACT [] synonym: "Blutbildungssystem" RELATED [BTO:0000570] xref: BTO:0000570 xref: EFO:0000798 ! haemopoietic system xref: FMA:9667 ! Hematopoietic system xref: GAID:1008 ! hematopoietic system xref: VHOG:0001624 ! hematopoietic system xref: MA:0002434 ! hematopoietic system xref: MAT:0000022 ! haemopoietic system xref: MIAA:0000022 ! haemopoietic system xref: TAO:0005023 ! hematopoietic system xref: XAO:0000122 ! hematological system xref: ZFA:0005023 ! hematopoietic system xref: ncithesaurus:Hematopoietic_System ! Hematopoietic System xref: MESH:A15.378 ! hematopoietic system xref: EV:0100045 ! hematological system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system relationship: part_of UBERON:0002193 ! hemolymphoid system xref: AAO:0011002 ! hematological system xref: SCTID:362587009 ! Entire hematopoietic system relationship: develops_from UBERON:0003061 {evidence="definitional"} ! blood island property_value: external_definition "Anatomical system that consists of the blood and blood forming tissues.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011002", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "Zebrafish developmental hematopoiesis shows close correspondence to the development of the mammalian hematopoietic system and is regulated by conserved molecular pathways.[well established][VHOG]" xsd:string {external_class="VHOG:0001624", ontology="VHOG", source="DOI:10.1016/j.coph.2010.05.004 Ellett F\, Lieschke GJ\, Zebrafish as a model for vertebrate hematopoiesis. Current Opinion in Pharmacology (2010)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0018957 property_value: has_relational_adjective "hematopoietic" xsd:string [Term] id: UBERON:0001011 name: hemolymph def: "Blood analogue used by all arthropods and most mollusks that have an open circulatory system. In these animals there is no distinction between blood and interstitial fluid. The liquid fills all of the interior (the hemocoel) of the body and surrounds all cells." [Wikipedia:Hemolymph] subset: uberon_slim synonym: "haemolymph" RELATED [] xref: BTO:0000572 xref: FBbt:00005061 ! hemolymph xref: GAID:1220 ! hemolymph xref: MAT:0000054 ! hemolymph xref: MIAA:0000054 ! hemolymph xref: TGMA:0000000 ! hemolymph xref: MESH:A13.453 ! hemolymph is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0001009 ! circulatory system [Term] id: UBERON:0001013 name: adipose tissue def: "Connective tissue composed of adipocytes." [Wikipedia:Adipose_tissue] comment: Note in FMA this is dense irregular connective tissue. Taxon notes: n humans, adipose tissue is located beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow) and in breast tissue. Adipose tissue is found in specific locations, which are referred to as adipose depots. Adipose tissue contains several cell types, with the highest percentage of cells being adipocytes, which contain fat droplets. Other cell types include fibroblasts, macrophages, and endothelial cells. Adipose tissue contains many small blood vessels.; Mice have eight major adipose depots, four of which are within the abdominal cavity. The paired gonadal depots are attached to the uterus and ovaries in females and the epididymis and testes in males; the paired retroperitoneal depots are found along the dorsal wall of the abdomen, surrounding the kidney, and, when massive, extend into the pelvis. The mesenteric depot forms a glue-like web that supports the intestines, and the omental depot, which originates near the stomach and spleen, and, when massive, extends into the ventral abdomen. subset: uberon_slim subset: vertebrate_core synonym: "fat tissue" EXACT [] synonym: "fatty tissue" EXACT [] synonym: "fatty depot" RELATED [] synonym: "fat" EXACT [MA:0000009] synonym: "adipose" RELATED [BTO:0001487] synonym: "bodyfat" RELATED [BTO:0001487] xref: AAO:0000001 ! adipose_tissue xref: EFO:0000234 ! adipose tissue xref: EFO:0000790 ! fat tissue xref: FMA:20110 ! Adipose tissue xref: GAID:920 ! adipose tissue xref: galen:FattyTissue xref: VHOG:0001284 ! adipose tissue xref: MA:0000009 ! adipose tissue xref: MAT:0000015 ! fat tissue xref: MIAA:0000015 ! fat tissue xref: OpenCyc:Mx4rvVjc_ZwpEbGdrcN5Y29ycA xref: XAO:0003049 ! adipose tissue xref: ncithesaurus:Adipose_Tissue ! Adipose Tissue xref: BTO:0001487 ! adipose tissue xref: OpenCyc:Mx4rvVjc_ZwpEbGdrcN5Y29ycA ! fatty tissue xref: EHDAA2:0003120 ! fat tissue xref: AEO:000020 ! fat tissue xref: ZFA:0005345 ! adipose tissue xref: MESH:A10.165.114 ! adipose tissue xref: EV:0100381 ! adipose tissue is_a: UBERON:0002384 {source="MA"} ! connective tissue intersection_of: UBERON:0000479 ! portion of tissue intersection_of: composed_primarily_of CL:0000136 ! fat cell disjoint_from: UBERON:0003714 ! neural tissue xref: SCTID:55603005 ! Adipose tissue xref: TAO:0002134 ! adipose tissue property_value: external_definition "Tissue that contains adipocytes, used for cushioning, thermal insulation, lubrication (primarily in the pericardium) and energy storage.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000001", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000001", date_retrieved="2012-06-20"} property_value: external_definition "Connective tissue in which fat is stored.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002134", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Adipose tissue is unique to vertebrates. It is found in mostmammals, birds, reptiles and amphibians, and a variety is found in some species of fish. Furthermore, in insects the fat body found in larvae as well as in adults shares some homology with adipose tissue.[well established][VHOG]" xsd:string {external_class="VHOG:0001284", ontology="VHOG", source="DOI:10.1017/S0029665107005423 Haugen F\, Drevon CA\, The interplay between nutrients and the adipose tissue. The Proceedings of the Nutrition Society (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0001527 property_value: has_relational_adjective "adipose" xsd:string [Term] id: UBERON:0003916 name: fat pad def: "a mass of closely packed fat cells (adipose tissue) surrounded by fibrous tissue septa[TMD]." [http://medical-dictionary.thefreedictionary.com/fat+pad, GO:0060613, BTO:0000444] comment: AO notes: FMA says isa fascia organ. Note that XAO and AAO have structures called fat pad/body, but these are gonad-associated, so we place them with the gonad-specific subclass synonym: "fat body" RELATED [FMA:58616] xref: BTO:0000444 ! fat pad xref: FMA:58616 ! Fat body xref: MA:0002481 ! fat pad is_a: UBERON:0001013 ! adipose tissue property_value: external_definition "An accumulation of adipose tissue (fat cells) enclosed in fibrous tissue[BTO]." xsd:string {ontology="BTO"} [Term] id: UBERON:0003917 name: arthropod fat body def: "an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism." [GO:0007503] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology synonym: "fat body" EXACT SENSU [FBbt:00005066] synonym: "fat body sensu invertebrata" RELATED [EFO:0000810] xref: FBbt:00005066 ! fat body xref: FBbt:00001704 ! embryonic/larval fat body xref: GAID:1213 ! fat body xref: MIAA:0000096 ! fat body xref: TADS:0000321 ! adult fat body xref: TGMA:0001856 ! fat body xref: BTO:0000442 ! fat body xref: MESH:A13.365 ! fat body xref: EFO:0000810 ! fat body sensu invertebrata is_a: UBERON:0001013 ! adipose tissue is_a: UBERON:0000062 ! organ relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda property_value: external_definition "A fatty tissue especially of nearly mature insect larvae that serves as a food reserve[BTO]." xsd:string {ontology="BTO"} [Term] id: UBERON:0012167 name: buccal fat pad def: "The Buccal fat pad is one of several encapsulated fat masses in the cheek. It is a deep fat pad located on either side of the face between the buccinator muscle and several more superficial muscles. It should not be confused with the malar fat pad, which is directly below the skin of the cheek. It should also not be confused with jowl fat pads. It is implicated in the formation of hollow cheeks and the nasolabial fold, but not in the formation of jowls." [Wikipedia:Buccal_fat_pad] synonym: "Bichat's fat pad" EXACT [FMA:59799] intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0001567 ! cheek xref: FMA:59799 ! buccal fat pad xref: SCTID:25930004 ! Buccal fat pad [Term] id: UBERON:0001014 name: obsolete fat body synonym: "fat pad" EXACT [] is_obsolete: true consider: UBERON:0003917 ! arthropod fat body [Term] id: UBERON:0001016 name: nervous system def: "a network of specialized cells that communicate information about an organism's surroundings and itself[Wikipedia]." [ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "Nervensystem" RELATED [BTO:0001484] xref: AAO:0000324 ! nervous_system xref: BILA:0000079 xref: EFO:0000802 ! nervous system xref: EHDAA:826 ! nervous system xref: FBbt:00005093 ! nervous system xref: FMA:7157 ! Nervous system xref: GAID:466 ! nervous system xref: VHOG:0000402 ! nervous system xref: MA:0000016 ! nervous system xref: MAT:0000026 ! nervous system xref: MIAA:0000026 ! nervous system xref: NIF_GrossAnatomy:birnlex_844 ! Nervous system xref: OpenCyc:Mx4rvViT_pwpEbGdrcN5Y29ycA xref: TAO:0000396 ! nervous system xref: WBbt:0005735 ! nervous system xref: XAO:0000177 ! nervous system xref: ZFA:0000396 ! nervous system xref: ncithesaurus:Nervous_System ! Nervous System xref: BTO:0001484 ! nervous system xref: OpenCyc:Mx4rvViT_pwpEbGdrcN5Y29ycA ! nervous system xref: EHDAA2:0001246 ! nervous system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Nervous_system_diagram.png/200px-Nervous_system_diagram.png xref: MESH:A08 ! nervous system xref: EMAPA:16469 ! nervous system of organ system xref: EV:0100162 ! nervous system (also: UBERON:0001021 'nerve') is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system relationship: develops_from UBERON:0000924 ! ectoderm relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa xref: SCTID:278196006 ! Entire nervous system synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg property_value: external_definition "Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000324", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: axiom_lost_from_external_ontology "relationship type change: differentiates_from ectoderm (AAO:0000137) CHANGED TO: develops_from ectoderm (UBERON:0000924)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000324", date_retrieved="2012-06-20"} property_value: external_definition "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000396", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG]" xsd:string {external_class="VHOG:0000402", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.117", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "neural" xsd:string property_value: has_relational_adjective "nervous" xsd:string xref: UMLS:C0027763 [Term] id: UBERON:0005743 ! central nervous system plus retina name: obsolete central nervous system plus retina is_obsolete: true comment: this class was originally added to account for some definitions of the CNS that includes retina. Most existing AOs use CNS to exclude the retina (ZFA retina NOT part_of CNS. XAO excludes retina in text def, retina (previously) part_of CNS. MA retina NOT part_of CNS. NIF_GA retina NOT part_of CNS. Fly also excludes it. EFO also excludes it. GO also excludes it). Whilst logically valid, the use case is better served by following the developmental relationships for retina. See: http://groups.google.com/group/pons-representation-and-deployment/browse_thread/thread/957da161a4dd4f85/a340e30cc8e9b2ce?lnk=gst&q=retina#a340e30cc8e9b2ce [Term] id: UBERON:0001017 ! central nervous system name: central nervous system def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord[GO]. The part of the nervous system which in vertebrates consists of the brain and spinal cord, to which sensory impulses are transmitted and from which motor impulses pass out, and which supervises and coordinates the activity of the entire nervous system[XAO]. Neuraxis plus retina[INCF]." [FB:gg, ISBN:3110148986, NLM:central+nervous+system, Wikipedia:Central_nervous_system, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "CNS" EXACT [] synonym: "cerebrospinal axis" EXACT [FMA:55675] synonym: "neuraxis" EXACT [FMA:55675] xref: FMA:55675 ! neuraxis xref: AAO:0000090 ! central_nervous_system xref: BILA:0000080 xref: BTO:0000227 xref: EFO:0000908 ! central nervous system xref: EHDAA:828 ! central nervous system xref: FBbt:00005094 ! central nervous system xref: GAID:570 ! central nervous system xref: VHOG:0000293 ! central nervous system xref: MA:0000167 ! central nervous system xref: MAT:0000457 ! central nervous system xref: NIF_GrossAnatomy:birnlex_1099 ! Central nervous system xref: TAO:0000012 ! central nervous system xref: XAO:0000215 ! central nervous system xref: ZFA:0000012 ! central nervous system xref: ncithesaurus:Central_Nervous_System ! Central Nervous System xref: OpenCyc:Mx4rvzYt3pwpEbGdrcN5Y29ycA ! central nervous system xref: EHDAA2:0000225 ! central nervous system xref: EMAPA:16470 ! central nervous system of nervous system of organ system xref: EMAPA:16754 ! central nervous system of nervous system of tail of embryo xref: MESH:A08.186 ! central nervous system xref: EV:0100163 ! central nervous system is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0001016 ! nervous system synonym: "systema nervosum centrale" EXACT LATIN [FMA:TA, FMA:55675] xref: SCTID:278199004 ! Entire central nervous system relationship: develops_from UBERON:0001049 {gci_relation="part_of", gci_filler="NCBITaxon:7742", evidence="definitional"} ! neural tube relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha property_value: external_definition "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000090", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000012", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]" xsd:string {external_class="VHOG:0000293", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1)\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.165 (reference 2)\, DOI:10.1016/j.cell.2007.02.040 Denes AS\, Jekely G\, Steinmetz PRH\, Raible F\, Snyman H\, Prud'homme B\, Ferrier DEK\, Balavoine G and Arendt D\, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0927232 [Term] id: UBERON:0001022 name: cell body def: "Cell component which consists of the plasma membrane and the cytoplasm surrounding the nucleus.[FMA]" [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html, Wikipedia:Cell_body, FMA:FMA] comment: TODO - use GO subset: uberon_slim synonym: "cell soma" EXACT [] synonym: "soma" RELATED [] xref: FBbt:00005107 ! cell body xref: FMA:67301 ! Cell body xref: GO:0043025 ! cell soma xref: NIF_Subcellular:sao1044911821 ! Neuronal Cell Body is_a: UBERON:0000470 ! cell part relationship: part_of CL:0000540 ! neuron [Term] id: UBERON:0001023 name: obsolete dendrite def: "The region of a neuron receiving inputs from other neurons, typically a slender neurite, often branched. In insect neurons, this is often not a clear designation and often presynaptic sites co-extend with postsynaptic ones." [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html, Wikipedia:Dendrite] comment: Made obsolete as it was equivalent to GO class subset: uberon_slim consider: FBbt:00005110 ! dendrite consider: FMA:67314 ! Dendrite consider: GAID:749 ! dendrite consider: ncithesaurus:Dendrite ! Dendrite consider: GO:0030425 ! dendrite consider: OpenCyc:Mx4rviIdspwpEbGdrcN5Y29ycA ! dendrite consider: NIF_Subcellular:sao1211023249 ! Dendrite consider: TGMA:0001373 ! dendrite consider: MESH:A08.663.256 ! dendrite is_obsolete: true property_value: has_relational_adjective "dendritic" xsd:string consider: UMLS:C0011305 [Term] id: UBERON:0001024 name: obsolete neurite def: "One of the processes or extensions of a neuron, axon or dendrite or cell body fiber. // Cell appendage of the neuron which includes the axon and the dendrite." [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html, Wikipedia:Neurite] comment: Made obsolete as it was equivalent to GO class subset: uberon_slim consider: FBbt:00005113 ! neurite consider: FMA:61814 ! Neurite consider: GAID:751 ! neurite consider: GO:0043005 ! neurite consider: NIF_Subcellular:sao-867568886 ! Neuron Process consider: MESH:A08.663.256.500 ! neurite is_obsolete: true [Term] id: UBERON:0001025 name: obsolete synapse def: "The structural contact that is the site of transmission between neurons, identified by a presynaptic ribbon and synaptic vesicles as the input element and one or (usually) more postsynaptic elements with various specializations (membrane densities, cisternae, etc.)." [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html, Wikipedia:Synapse] comment: Made obsolete as it was equivalent to GO class subset: uberon_slim synonym: "synaptic junction" EXACT [] consider: FBbt:00005114 ! synapse consider: FMA:67408 ! Synapse consider: GAID:766 ! synapse consider: GO:0045202 consider: ncithesaurus:Synapse ! Synapse consider: NIF_Subcellular:sao914572699 ! Synapse consider: MESH:A08.850 ! synapse consider: SCTID:362298009 ! Entire synapse consider: UMLS:C0039062 property_value: has_relational_adjective "synaptic" xsd:string is_obsolete: true [Term] id: UBERON:0001026 name: obsolete motor nerve def: "General anatomical term applied to nerves in which somatic efferent nerve fibers predominate[FMA]. A motor nerve is an efferent nerve that exclusively contains the axons of somatic and branchial motoneurons, which innervate skeletal muscles (that ensure locomotion) and branchial muscles (that motorize the face and neck)[WP]." [Wikipedia:Motor_nerve] synonym: "efferent nerve" RELATED [] synonym: "nervus motorius" EXACT [] is_obsolete: true [Term] id: UBERON:0001027 name: sensory nerve def: "A group of neurons that provides a nervous response from a tissue[AEO]." [AEO:0000201, Wikipedia:Sensory_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "afferent nerve" RELATED [] synonym: "nervus sensorius" EXACT [] xref: FBbt:00005136 ! sensory nerve xref: FMA:5868 ! Sensory nerve xref: OpenCyc:Mx4rv0GdXpwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rv0GdXpwpEbGdrcN5Y29ycA ! sensory nerve xref: EHDAA2:0003200 ! afferent nerve xref: AEO:0000201 ! afferent nerve is_a: UBERON:0001021 ! nerve relationship: has_part CL:0000526 {source="AEO"} ! afferent neuron synonym: "nervus sensorius" RELATED LATIN [Wikipedia:Sensory_nerve] property_value: external_definition "General anatomical term applied to nerves in which somatic afferent nerve fibers predominate[FMA]. nerves that receive sensory stimuli made up of nerve fibers, called sensory fibers (mechanoreceptor fibers sense body movement and pressure placed against the body, and nociceptor fibers sense tissue injury)[WP][Wikipedia:Sensory_nerve]." xsd:string {source="Wikipedia:Sensory_nerve"} [Term] id: UBERON:0006798 name: efferent nerve def: "A group of neurons that provides a nervous signal to a tissue." [AEO:JB] xref: EHDAA2:0003231 ! efferent nerve xref: AEO:0000202 is_a: UBERON:0001021 ! nerve relationship: has_part CL:0000527 {source="AEO"} ! efferent neuron [Term] id: UBERON:0001029 name: neuromuscular junction def: "." [Wikipedia:Neuromuscular_junction] comment: TODO - use GO subset: uberon_slim synonym: "myoneural junction" EXACT [] xref: FBbt:00005142 ! neuromuscular junction xref: FMA:61803 ! Neuromuscular junction xref: GAID:809 ! neuromuscular junction xref: GO:0031594 ! neuromuscular junction xref: NIF_Subcellular:sao1124888485 ! Neuromuscular Junction xref: MESH:A08.800.550.550.550 ! neuromuscular junction is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001016 ! nervous system synonym: "synapsis neuromuscularis; junctio neuromuscularis" RELATED LATIN [Wikipedia:Neuromuscular_junction] xref: http://upload.wikimedia.org/wikipedia/commons/2/23/NMJ.jpg [Term] id: UBERON:0001030 name: obsolete synaptic ribbon synonym: "ribbon synapse" EXACT [] consider: FBbt:00005143 ! synaptic ribbon consider: FMA:67107 ! Ribbon synapse consider: NIF_Subcellular:sao1884931180 ! Ribbon Synapse consider: GO:0048788 ! presynaptic cytoskeletal matrix assembled at active zones is_obsolete: true [Term] id: UBERON:0001031 name: neurilemma def: "thin membranous sheath around a nerve fiber[TFD]." [Wikipedia:Neurilemma, http://www.thefreedictionary.com/neurolemma] comment: FMA def is 'Neural tissue which consists of Schwann cells' which does not fit, but we still use 'neural tissue' here. WP def specifically states Schwann cells, which would restrict it to PNS subset: uberon_slim synonym: "neurolemma" EXACT [] synonym: "sheath of Schwann" EXACT [] synonym: "endoneural membrane" RELATED [BTO:0003048] synonym: "Schwann's membrane" RELATED [BTO:0003048] xref: FBbt:00005151 ! neurilemma xref: FMA:62976 ! Neurilemma xref: GAID:730 ! neurilemma xref: ncithesaurus:Sheath_of_Schwann ! Sheath of Schwann xref: BTO:0003048 ! neurolemma xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Gray631.png/200px-Gray631.png xref: MESH:A08.561.600 ! neurilemma is_a: UBERON:0003714 ! neural tissue relationship: part_of UBERON:0001016 ! nervous system xref: UMLS:C0027807 [Term] id: UBERON:0004456 ! entire sense organ system name: entire sense organ system def: "Sum of all sensory systems in an organism." [] comment: note the distinct between entire sensory system and individual system. this reconciles is_a and part_of distinctions between ssAOs subset: uberon_slim synonym: "sense organ system" EXACT [FMA:78499] xref: FMA:78499 ! Sense organ system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system relationship: overlaps UBERON:0001016 ! nervous system [Term] id: UBERON:0001032 name: sensory system def: "Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information." [Wikipedia:Sensory_system] comment: note the distinct between entire sensory system and individual system. this reconciles is_a and part_of distinctions between ssAOs subset: uberon_slim subset: vertebrate_core synonym: "sense organ subsystem" EXACT [] synonym: "sensory organ system" RELATED [] synonym: "sensory subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] xref: AAO:0000555 ! sensory_system xref: BILA:0000099 xref: EFO:0000805 ! sensory system xref: MA:0002442 ! sensory organ system xref: MAT:0000031 ! sensory system xref: MIAA:0000031 ! sensory system xref: TAO:0000282 ! sensory system xref: ZFA:0000282 ! sensory system xref: FBbt:00005827 ! embryonic sensory system xref: XAO:0003194 ! sensory system xref: FMA:75259 ! Set of sense organs xref: NIF_GrossAnatomy:nlx_anat_090816 ! Sensory system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Gray722.png/200px-Gray722.png xref: EHDAA2:0003094 ! sense organ is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0004456 ! entire sense organ system relationship: overlaps UBERON:0001016 ! nervous system synonym: "organa sensuum" EXACT LATIN [FMA:TA, FMA:75259] synonym: "organa sensuum" RELATED LATIN [Wikipedia:Sensory_system] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png xref: VHOG:0001674 ! sensory system synonym: "set of sense organs" RELATED [FMA:75259] synonym: "sensory systems" EXACT PLURAL [TAO:0000282] property_value: homology_notes "An early step in the evolution of neural crest, therefore, may have been the origin of a specific dorsal neural cell population contributing to sensory processing; this would predate the divergence of the amphioxus and vertebrate lineages.[well established][VHOG]" xsd:string {external_class="VHOG:0001674", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001033 name: gustatory system def: "A subset of the sensory system for the sensing of taste." [Wikipedia:Gustatory_system] comment: in ZFA and MA this is a subtype of sensory system. we should change sensory system to disambiguate parts and wholes subset: uberon_slim subset: vertebrate_core synonym: "gustatory organ system" EXACT [] synonym: "taste system" EXACT [] xref: BILA:0000143 xref: EFO:0000830 ! taste system xref: FMA:7194 ! Gustatory system xref: MA:0002446 ! gustatory system xref: MAT:0000275 ! taste system xref: MIAA:0000275 ! taste system xref: TAO:0001101 ! gustatory system xref: ZFA:0001101 ! gustatory system xref: XAO:0003197 ! gustatory system xref: NIF_GrossAnatomy:nlx_anat_090803 ! Gustatory system xref: XAO:0003197 ! gustatory system intersection_of: UBERON:0000467 ! anatomical system intersection_of: has_function_in GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system xref: AAO:0010577 ! gustatory system xref: SCTID:423940004 ! Structure of gustatory system property_value: external_definition "The sensory system used for the sense of taste.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010577", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: has_relational_adjective "gustatory" xsd:string [Term] id: UBERON:0001034 name: obsolete photoreceptor def: "Can refer to a light sensitive organ, a photoreceptor cell or a photoreceptor protein. This class was made obsolete because it was ambiguous" [Wikipedia:Photoreceptor] xref: BTO:0001060 consider: FBbt:00005162 ! photoreceptor consider: FMA:85613 ! Photoreceptor consider: GAID:778 ! photoreceptor is_obsolete: true consider: CL:0000210 [Term] id: UBERON:0001035 name: dento-alveolar joint def: "Fibrous joint in which the periodontal ligament connects a tooth to the alveolar bone of the maxilla or mandible. Examples: Dento-alveolar joint of incisor tooth.[FMA]" [Wikipedia:Gomphosis, FMA:FMA] comment: This class was created automatically from a combination of ontologies synonym: "dento-alveolar syndesmosis" EXACT [FMA:7495] synonym: "peg-and-socket joint" EXACT [FMA:7495] synonym: "socket" BROAD [FMA:7495] synonym: "gomphosis" EXACT [MA:0001499] xref: FMA:7495 ! Dento-alveolar joint xref: MA:0001499 ! gomphosis xref: OpenCyc:Mx4rveAQeZwpEbGdrcN5Y29ycA ! gomphosis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6c/Gray1003.png/200px-Gray1003.png is_a: UBERON:0002209 {source="FMA"} ! fibrous joint is_a: UBERON:0002213 {source="MA"} ! cartilaginous joint relationship: part_of UBERON:0001708 ! jaw relationship: connects UBERON:0004103 ! alveolar ridge relationship: connects UBERON:0001091 ! calcareous tooth synonym: "syndesmosis dentoalveolaris" EXACT LATIN [FMA:TA, FMA:7495] xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray1003.png xref: SCTID:50870008 ! Entire gomphosis [Term] id: UBERON:0011120 name: laryngeal joint synonym: "joint of larynx" EXACT [FMA:55100] synonym: "laryngeal articulation" EXACT [FMA:55100] is_a: UBERON:0002217 {source="FMA"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001739 ! laryngeal cartilage relationship: part_of UBERON:0010323 ! cranial skeletal system xref: FMA:55100 ! laryngeal joint def: "A skeletal joint that connects a laryngeal cartilage." [OBOL:automatic] [Term] id: UBERON:0011121 name: cricothyroid joint def: "The cricoarytenoid articulation (or joint) is a joint connecting the cricoid cartilage and the thyroid cartilage." [Wikipedia:Cricothyroid_articulation] synonym: "crico-thyroid joint" RELATED [Wikipedia:Cricothyroid_articulation] synonym: "cricothyroid articulation" EXACT [FMA:55101] is_a: UBERON:0011120 {source="FMA"} ! laryngeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001738 ! thyroid cartilage intersection_of: connects UBERON:0002375 ! cricoid cartilage relationship: part_of UBERON:0010323 {source="cjm"} ! cranial skeletal system xref: FMA:55101 ! cricothyroid joint xref: ncithesaurus:Cricothyroid_Joint ! cricothyroid joint xref: http://upload.wikimedia.org/wikipedia/commons/8/8a/Larynx_external_en.svg xref: SCTID:361944002 ! Entire cricothyroid articulation xref: UMLS:C0225540 [Term] id: UBERON:0011122 name: cricoarytenoid joint def: "The cricoarytenoid articulation (or joint) is a joint connecting the cricoid cartilage and the arytenoid cartilage." [Wikipedia:Cricoarytenoid_articulation] synonym: "crico-arytenoid joint" RELATED [Wikipedia:Cricoarytenoid_articulation] synonym: "cricoarytenoid articulation" EXACT [FMA:55102] synonym: "crico-arytenoid joint" EXACT [FMA:55102] is_a: UBERON:0011120 {source="FMA"} ! laryngeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001740 ! arytenoid cartilage intersection_of: connects UBERON:0002375 ! cricoid cartilage relationship: part_of UBERON:0010323 {source="cjm"} ! cranial skeletal system xref: FMA:55102 ! crico-arytenoid joint xref: ncithesaurus:Cricoarytenoid_Joint ! cricoarytenoid joint xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray960.png xref: SCTID:361945001 ! Entire cricoarytenoid articulation xref: UMLS:C0225555 [Term] id: UBERON:0011932 name: pilosebaceous unit def: "An epidermal invagination that has as parts a hair follicle, a sebaceous gland, and arrector pili muscle" [Wikipedia:Pilosebaceous_unit, PMC:PMC3130146] synonym: "pilo-sebaceous apparatus" EXACT [FMA:70661] synonym: "pilo-sebaceous unit" EXACT [] synonym: "pilosebaceous apparatus" EXACT [] synonym: "fabrica pilosebacea" EXACT [Wikipedia:Pilosebaceous_unit] is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: part_of UBERON:0002416 ! integumental system xref: FMA:70661 ! pilosebaceous unit [Term] id: UBERON:0001037 name: strand of hair def: "A filament, mostly protein, that grows from follicles found in the dermis[WP]." [Wikipedia:Hair] comment: this class defines an individual hair. todo - consider fur / coat of fur, which has_part hair. TODO: for now we treat vibrissa/whisker as a syonym, but these have different follicles. We could introduce subclasses (see also: Pangolin scales) subset: uberon_slim synonym: "hair" EXACT [] synonym: "coat hair" RELATED [] synonym: "coat/ hair" RELATED [] synonym: "microchaeta" RELATED [] synonym: "setulae" RELATED [] synonym: "vibrissa" RELATED SENSU [] synonym: "whisker" RELATED SENSU [] synonym: "quill" RELATED SENSU [] synonym: "fur" RELATED [] xref: FMA:53667 ! Hair xref: GAID:71 ! hair xref: VHOG:0001191 ! hair xref: MA:0000155 ! coat hair xref: MAT:0000160 ! hair xref: MIAA:0000160 ! hair xref: OpenCyc:Mx4rvVjOX5wpEbGdrcN5Y29ycA-Mp88EdaAAACgycbRww xref: ncithesaurus:Hair ! Hair xref: BTO:0001501 ! hair xref: EFO:0000958 ! hair xref: EMAPA:18769 ! hair xref: MESH:A17.360 ! hair xref: EV:0100157 ! hair is_a: UBERON:0000021 {source="FMA"} ! cutaneous appendage relationship: part_of UBERON:0011932 {source="FMA"} ! pilosebaceous unit relationship: part_of UBERON:0001003 {source="FMA"} ! epidermis relationship: develops_from UBERON:0002073 ! hair follicle relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: SCTID:361702001 ! Entire hair xref: http://upload.wikimedia.org/wikipedia/commons/2/25/Gray945.png xref: UMLS:C0018494 [Term] id: UBERON:0000329 name: hair root def: "The enlarged basal part of a hair within the skin[BTO]. The root of the hair ends in an enlargement, the hair bulb, which is whiter in color and softer in texture than the shaft, and is lodged in a follicular involution of the epidermis called the hair follicle. [Wikipedia]." [Wikipedia:Hair_root, BTO:0000555] synonym: "root of hair" EXACT [FMA:70730] xref: BTO:0000555 ! hair root xref: FMA:70730 ! Hair root xref: ncithesaurus:Hair_Root ! Hair Root xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5e/Gray944.png/200px-Gray944.png is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001037 ! hair xref: UMLS:C1182707 [Term] id: UBERON:0002073 name: hair follicle def: "a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open[GO]." [Wikipedia:Hair_follicle] subset: uberon_slim xref: BTO:0000554 xref: FMA:70660 ! Hair follicle xref: GAID:934 ! hair follicle xref: VHOG:0001268 ! hair follicle xref: MA:0000154 ! hair follicle xref: OpenCyc:Mx4rvVjOI5wpEbGdrcN5Y29ycA xref: ncithesaurus:Hair_Follicle ! Hair Follicle xref: EFO:0002464 ! hair follicle xref: OpenCyc:Mx4rvVjOI5wpEbGdrcN5Y29ycA ! hair follicle xref: EMAPA:29741 ! hair follicle xref: EMAPA:18771 ! follicle of hair xref: MESH:A10.272.497.500 ! hair follicle xref: EV:0100156 ! hair follicle is_a: UBERON:0000025 ! tube relationship: overlaps UBERON:0001037 ! hair relationship: part_of UBERON:0011932 {source="FMA"} ! pilosebaceous unit relationship: part_of UBERON:0001003 {source="FMA"} ! epidermis relationship: develops_from UBERON:0005086 ! hair follicle placode xref: SCTID:280830006 ! Entire hair follicle subset: organ_slim synonym: "folliculus pili" RELATED LATIN [Wikipedia:Hair_follicle] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Hair_follicle-en.svg property_value: homology_notes "The earliest reliable record of hair is found in a fossil of the Paleocene period, in which the structure of hair cuticles is preserved. Its appearance suggests that the complicated structure of the hair follicle, closely similar to that of present-day mammals, had already appeared at this time.[well established][VHOG]" xsd:string {external_class="VHOG:0001268", ontology="VHOG", source="ISBN:978-4431998051 Morioka K\, Hair follicle: differentiation under the electron microscope\, An atlas (2005) p.3", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0221971 [Term] id: UBERON:0010419 name: vibrissa follicle intersection_of: UBERON:0002073 ! hair follicle intersection_of: part_of UBERON:0011933 ! vibrissa unit synonym: "follicle of vibrissa" EXACT [EMAPA:26720] synonym: "vibrissa follicle" RELATED [MP:0010234] synonym: "follicle of sinus hair" EXACT [EMAPA:26759] xref: MA:0002910 ! vibrissa follicle xref: EMAPA:26720 ! follicle of vibrissa xref: EMAPA:26759 ! follicle of sinus hair def: "A hair follicle that is part of a vibrissa unit." [OBOL:automatic] [Term] id: UBERON:0011817 ! follicle placode name: follicle placode comment: Includes hair and feather follicles is_a: UBERON:0011814 {source="NBK53175"} ! non-neurogenic ectodermal placode relationship: has_developmental_contribution_from UBERON:0001003 ! epidermis relationship: has_developmental_contribution_from UBERON:0002067 ! dermis [Term] id: UBERON:0005086 ! hair follicle placode name: hair follicle placode def: "An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud[GO]." [GO:0060789] synonym: "hair gem" RELATED [ISBN:9780878932504 "Developmental Biology"] synonym: "hair peg" RELATED [ISBN:9780878932504 "Developmental Biology"] synonym: "vibrissa placode" NARROW [] is_a: UBERON:0011817 ! follicle placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: develops_into UBERON:0002073 ! hair follicle relationship: develops_from UBERON:0001003 ! epidermis relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer [Term] id: UBERON:0002074 name: hair shaft def: "The non-growing portion of a hair which protrudes from the skin, i.e., from the follicle[BTO]. the cuticle, and/or cortex and/or medulla of a hair[MP]." [BTO:0004672, MP:0003809] comment: TODO - add distinct subclasses for coat hair vs vibrissa hair synonym: "scapus pili" RELATED [BTO:0004672] synonym: "shaft of hair" EXACT [] xref: FMA:70728 ! Hair shaft xref: MA:0000159 ! hair shaft xref: BTO:0004672 ! hair shaft is_a: UBERON:0000021 ! cutaneous appendage relationship: part_of UBERON:0001037 {source="FMA"} ! strand of hair xref: ncithesaurus:Shaft_of_the_Hair ! Shaft of the Hair xref: SCTID:361359004 ! Entire hair shaft xref: UMLS:C0221961 [Term] id: UBERON:0005184 name: hair medulla def: "Innermost layer of the hair shaft." [Wikipedia:Bone_marrow_of_ovary_(hair)] synonym: "medulla of hair shaft" RELATED [BTO:0004671] xref: MA:0000158 ! hair medulla xref: BTO:0004671 ! hair medulla intersection_of: UBERON:0000958 ! medulla intersection_of: part_of UBERON:0001037 ! hair xref: SCTID:318929009 ! Entire hair medulla [Term] id: UBERON:0005932 ! bulb of hair follicle name: bulb of hair follicle comment: see https://sourceforge.net/tracker/?func=detail&aid=3213510&group_id=76834&atid=1205376 synonym: "hair bulb" EXACT [FMA:70666] synonym: "hair follicle bulb" EXACT [FMA:70666] synonym: "coat hair bulb" NARROW SENSU [MA:0000161] xref: FMA:70666 ! bulb of hair follicle xref: MA:0000161 ! coat hair bulb xref: EMAPA:18770 ! bulb of hair is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002073 ! hair follicle xref: ncithesaurus:Hair_Bulb ! Hair Bulb xref: SCTID:361360009 ! Entire hair bulb xref: UMLS:C0221962 [Term] id: UBERON:0011936 name: vibrissa hair bulb comment: see https://sourceforge.net/tracker/?func=detail&aid=3213510&group_id=76834&atid=1205376 synonym: "vibrissa bulb" EXACT [EMAPA:26716] synonym: "bulb of vibrissa follicle" EXACT [] synonym: "bulb of sinus hair" EXACT [EMAPA:26753] intersection_of: UBERON:0005932 ! bulb of hair follicle intersection_of: part_of UBERON:0011933 ! vibrissa unit xref: MA:0000783 ! vibrissa hair bulb xref: EMAPA:26716 ! bulb xref: EMAPA:26753 ! bulb def: "A bulb of hair follicle that is part of a vibrissa unit." [OBOL:automatic] relationship: part_of UBERON:0010419 {is_inferred="true", source="reference_0000032"} ! vibrissa follicle [Term] id: UBERON:0005968 ! infundibulum of hair follicle name: infundibulum of hair follicle def: "the portion of the hair follicle from the entrance of the sebaceous gland duct to the surface opening." [https://sourceforge.net/tracker/?func=detail&aid=3565357&group_id=76834&atid=1205376, UBERON:ps] synonym: "dermal piliary canal" EXACT [FMA:70722] synonym: "hair follicle infundibulum" EXACT [FMA:70722] xref: MA:0003016 ! hair follicle infundibulum xref: FMA:70722 ! infundibulum of hair follicle is_a: UBERON:0000061 ! anatomical structure disjoint_from: UBERON:0002434 ! pituitary stalk relationship: part_of UBERON:0002073 ! hair follicle xref: ncithesaurus:Hair_Follicle_Infundibulum ! Hair Follicle Infundibulum xref: SCTID:319522000 ! Entire infundibulum of hair follicle xref: UMLS:C0221973 [Term] id: UBERON:0005933 ! hair root sheath name: hair root sheath comment: AO notes: see https://sourceforge.net/tracker/?func=detail&aid=3213510&group_id=76834&atid=1205376 xref: MA:0000162 ! hair root sheath xref: EMAPA:18772 ! root sheath of hair is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0005932 ! bulb of hair follicle [Term] id: UBERON:0011937 name: vibrissa root sheath intersection_of: UBERON:0005933 ! hair root sheath intersection_of: part_of UBERON:0011933 ! vibrissa unit synonym: "root sheath of sinus hair" EXACT [EMAPA:26765] synonym: "root sheath of vibrissa" EXACT [] synonym: "root sheath of vibrissa hair" EXACT [] xref: MA:0000784 ! vibrissa root sheath xref: EMAPA:26724 ! root sheath of vibrissa xref: EMAPA:26765 ! root sheath of sinus hair def: "A hair root sheath that is part of a vibrissa unit." [OBOL:automatic] relationship: part_of UBERON:0011936 {is_inferred="true", source="reference_0000032"} ! vibrissa hair bulb [Term] id: UBERON:0005941 ! hair inner root sheath name: hair inner root sheath def: "A multilayered tube composed of terminally differentiated hair follicle keratinocytes that is surrounded by the outer root sheath; the layers of the inner root sheath include the companion layer, Henle's layer, Huxley's layer and the inner root sheath cuticle[MP]." [MP:0010685, https://sourceforge.net/tracker/?func=detail&aid=3213510&group_id=76834&atid=1205376] synonym: "hair follicle inner root sheath" EXACT [MP:0010685] synonym: "inner root sheath" RELATED [BTO:0003971] synonym: "inner root sheath of hair follicle" EXACT [FMA:70935] synonym: "inner sheath of hair follicle" EXACT [FMA:70935] synonym: "internal root sheath of hair follicle" EXACT [FMA:70935] xref: BTO:0003971 ! hair follicle inner root sheath xref: MA:0000779 ! hair inner root sheath xref: FMA:70935 ! inner root sheath of hair follicle is_a: UBERON:0005933 ! hair root sheath [Term] id: UBERON:0011938 name: vibrissa inner root sheath xref: MA:0000785 ! vibrissa inner root sheath intersection_of: UBERON:0005941 ! hair inner root sheath intersection_of: part_of UBERON:0011933 ! vibrissa unit def: "A hair inner root sheath that is part of a vibrissa unit." [OBOL:automatic] relationship: part_of UBERON:0011936 {source="reference_0000032"} ! vibrissa hair bulb [Term] id: UBERON:0005942 ! hair outer root sheath name: hair outer root sheath def: "It surrounds the hair follicle like a sleeve all the way to the bulb. The outer root sheath is essentially a stratified epithelium that is contiguous with the epidermis." [Keratin.com:http://www.keratin.com/, https://sourceforge.net/tracker/?func=detail&aid=3213510&group_id=76834&atid=1205376] synonym: "ORS" RELATED [BTO:0003969] synonym: "outer root sheath" RELATED [BTO:0003969] synonym: "hair follicle outer root sheath" EXACT [BTO:0003969] synonym: "outer root sheath of hair follicle" EXACT [FMA:70943] synonym: "external root sheath of hair follicle" EXACT [FMA:70943] xref: MA:0000780 ! hair outer root sheath xref: BTO:0003969 ! hair follicle outer root sheath xref: FMA:70943 ! outer root sheath of hair follicle is_a: UBERON:0005933 ! hair root sheath xref: SCTID:319224003 ! Entire outer root sheath [Term] id: UBERON:0011939 name: vibrissa outer root sheath intersection_of: UBERON:0005942 ! hair outer root sheath intersection_of: part_of UBERON:0011933 ! vibrissa unit xref: MA:0000786 ! vibrissa outer root sheath def: "A hair outer root sheath that is part of a vibrissa unit." [OBOL:automatic] relationship: part_of UBERON:0011936 {source="reference_0000032"} ! vibrissa hair bulb [Term] id: UBERON:0005943 name: hair root sheath matrix xref: MA:0000781 ! hair root sheath matrix is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0005933 ! hair root sheath [Term] id: UBERON:0000412 ! dermal papilla name: dermal papilla def: "small, nipple-like extensions (or interdigitations) of the dermis into the epidermis. They can be observed at the surface of the skin in hands and feet as epidermal or papillary ridges (colloquially known as fingerprints). The dermal papillae nourishes all hair follicles and bring food and oxygen to the lower layers of epidermal cells. The pattern of ridges they produce in hands and feet are inherited features that are developed before birth. They remain unaltered (except size) throughout life, and are therefore used for fingerprints. The dermal papillae are part of the uppermost layer of the dermis, the papillary dermis, and the ridges they form greatly increase the surface area between the dermis and epidermis. Because the dermis' main function is to support the epidermis, this greatly increases the exchange of oxygen, nutrients, and waste products between these two layers. Additionally, the increase in surface area prevent the dermal and epidermal layers from separating from each others by strengthening the junction between them. With age, the papillae tend to flatten and sometimes increase in numbers. Dermal papillae also play a pivotal role in hair formation, growth and, cycling" [Wikipedia:Dermal_papillae] comment: Consider adding grouping class for TAO:0001995 ! papilla synonym: "dermal papillae" EXACT PLURAL [] synonym: "follicular papilla" EXACT [FMA:70737] synonym: "hair follicle dermal papilla" RELATED [MP:0010687] synonym: "dermal papilla cell" RELATED [BTO:0001858] synonym: "DPC" RELATED [BTO:0001858] synonym: "papilla corii" RELATED [BTO:0001858] synonym: "papilla dermatis" RELATED [BTO:0001858] synonym: "papilla dermis" RELATED [BTO:0001858] synonym: "papilla of corium" RELATED [BTO:0001858] synonym: "skin papilla" RELATED [BTO:0001858] xref: BTO:0001858 xref: FMA:70737 ! Dermal papilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Skin.jpg/200px-Skin.jpg is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001992 ! papillary layer of dermis xref: ncithesaurus:Dermal_Papilla ! Dermal Papilla xref: SCTID:320101005 ! Entire dermal papilla synonym: "papillae dermis" RELATED LATIN [Wikipedia:Dermal_papillae] xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Skin.jpg xref: UMLS:C0221931 [Term] id: UBERON:0001992 name: papillary layer of dermis def: "Dense irregular connective tissue of the skin that consists of fibroblasts, various connective tissue cell types, and collagen, predominantly type III.[FMA]" [Wikipedia:Papillary_dermis, FMA:FMA] comment: AO notes: check AO subset: uberon_slim synonym: "corpus papillary" EXACT [MP:0009545] synonym: "papillary layer" EXACT [MP:0009545] synonym: "stratum papillare corii" EXACT [MP:0009545] synonym: "stratum papillare" EXACT [MP:0009545] synonym: "superficial dermis" EXACT [MP:0009545] synonym: "papillary layer of dermis" EXACT [FMA:64776] synonym: "dermis papillary layer" EXACT [] synonym: "papillary dermis" EXACT [] synonym: "superficial dermis" EXACT [MA:0000802] synonym: "dermis papillary layer" EXACT [MA:0000800] xref: FMA:64776 ! Papillary layer of dermis xref: MA:0000800 ! dermis papillary layer xref: MA:0000802 ! superficial dermis is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0002067 ! dermis xref: ncithesaurus:Papillary_Dermis ! papillary dermis xref: ncithesaurus:Stratum_Papillare ! stratum papillare synonym: "stratum papillare" RELATED LATIN [Wikipedia:Papillary_dermis] xref: http://upload.wikimedia.org/wikipedia/commons/b/b4/Normal_Epidermis_and_Dermis_with_Intradermal_Nevus_10x.JPG xref: UMLS:C0682598 xref: UMLS:C0221930 [Term] id: UBERON:0007377 ! stratum compactum name: stratum compactum def: "Portion of the dermis characterized by a well-arranged, plywood-like, collagenous network." [ZFIN:ZDB-PUB-040726-12, ISBN10:0073040584 "Vertebrates\, Kardong"] comment: connective tissue in the skin is usually diffuse and irregular, although in some species collagen bundles are arranged in a distinct ordered layer in the dermis synonym: "dermal deep region" EXACT [ZFA:0001182] xref: TAO:0001182 ! dermal deep region xref: ZFA:0001182 ! dermal deep region is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0002067 ! dermis xref: AAO:0010600 ! stratum compactum property_value: external_definition "Portion of the dermis characterized by a well-arranged, plywood-like, collagenous network. Le Guellec et al, 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001182", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from collagenous dermal stroma (TAO:0001186)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001182", date_retrieved="2012-08-14"} [Term] id: UBERON:0012244 name: stratum intermedium of epidermis def: "A temporary layer between old and new skin that is invalided by white blood cells[Kardong]." [ISBN10:0073040584] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0001003 {source="Kardong"} ! epidermis [Term] id: UBERON:0001993 name: reticular layer of dermis def: "lower layer of the dermis, found under the papillary dermis, composed of dense irregular connective tissue featuring densely packed collagen fibers. It is the primary location of dermal elastic fibers." [Wikipedia:Reticular_dermis] subset: uberon_slim synonym: "dermis reticular layer" EXACT [] synonym: "reticular dermis" EXACT [] synonym: "stratum reticulare" EXACT [Wikipedia:Reticular_dermis] xref: FMA:64778 ! Reticular layer of dermis xref: MA:0000801 ! dermis reticular layer is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0002067 ! dermis relationship: part_of UBERON:0008877 {source="FMA"} ! epidermal-dermal junction relationship: adjacent_to UBERON:0001992 ! papillary layer of dermis xref: ncithesaurus:Reticular_Dermis ! reticular dermis xref: ncithesaurus:Stratum_Reticulare ! stratum reticulare synonym: "stratum reticulare" RELATED LATIN [Wikipedia:Reticular_dermis] xref: UMLS:C0682599 xref: UMLS:C1514988 [Term] id: UBERON:0005198 name: obsolete coat hair bulb is_obsolete: true [Term] id: UBERON:0001038 name: chordotonal organ def: "Chordotonal organs are arthropod sensory structures consisting of special sensilla called the scolopidia, which are mechano-transducers and respond mainly to stretch or flexion. In insects, they consist of bundles of internal sensilla, each of which has a cap cell, an enveloping cell and one or more sense cells. The distal end of the organ is usually attached to the cuticle of the body wall, marked by a pit, a thickened disc or a nodule of chitin, and the base of the organ is connected with the hypodermis, often by a special ligament." [FB:FBrf0056378, Wikipedia:Chordotonal_organ] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "ch" RELATED [] synonym: "scolopophorous organ" RELATED [] xref: FBbt:00005215 ! chordotonal organ xref: MAT:0000209 ! chordotonal organ xref: MIAA:0000209 ! chordotonal organ xref: EFO:0000940 ! chordotonal organ is_a: UBERON:0000020 ! sense organ relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda subset: organ_slim [Term] id: UBERON:0008852 ! visceral yolk sac name: visceral yolk sac def: "extraembryonic tissue membrane, formed from the visceral endoderm and the extraembryonic mesoderm, which is located ventral to the embryonic disc and is connected to the presumptive midgut of the embryo; the yolk that it contains is the site of embryonic hematopoiesis and vitelline circulation is involved in early embryonic circulation; it is the origin of the primordial germ cells" [MP:0001718] comment: TODO - check synonym: "secondary yolk sac" EXACT [MP:0001718] synonym: "umbilical vesicle" EXACT [MP:0001718] synonym: "vitelline sac" EXACT [MP:0001718] synonym: "yolk sac" BROAD [MP:0001718] is_a: UBERON:0001040 ! yolk sac [Term] id: UBERON:0008853 name: parietal yolk sac def: "tissue that consists of two cellular layers (parietal endoderm and trophoblast) separated by a relatively thick nonvascular basement membrane (Reichert's membrane), and acts as a protective layer to supports and facilitates transport of nutrients between the uterine tissue and the yolk sac cavity." [PMID:1150659, PMID:21123814, MP:0011203] synonym: "primary yolk sac" EXACT [MP:0011203] is_a: UBERON:0001040 ! yolk sac xref: EHDAA2:0003237 ! primary yolk sac [Term] id: UBERON:0001040 name: yolk sac def: "Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes." [Wikipedia:Yolk_sac] comment: Taxon notes: In therians, a structure homologous to the yolk sac is is present, but contains no yolk platelets. Instead it is filled with fluid [ISBN10:0073040584 "Vertebrates\, Kardong"] subset: uberon_slim synonym: "vesicula umbilicalis" RELATED LATIN [Wikipedia:Yolk_sac] synonym: "saccus vitellinus" RELATED LATIN [Wikipedia:Yolk_sac] xref: EHDAA:164 ! yolk sac xref: FMA:87180 ! Yolk sac xref: GAID:1301 ! yolk sac xref: VHOG:0000830 ! yolk sac xref: ncithesaurus:Yolk_Sac ! Yolk Sac xref: BTO:0001471 ! yolk sac xref: EHDAA2:0002212 ! yolk sac xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/17/Gray22.png/200px-Gray22.png xref: EMAPA:16085 ! yolk sac xref: MESH:A16.254.403.981 ! yolk sac xref: EFO:0003078 ! yolk sac is_a: UBERON:0005631 ! extraembryonic membrane relationship: develops_from UBERON:0004872 {source="ISBN10:0073040584"} ! splanchnic layer of lateral plate mesoderm relationship: develops_from UBERON:0000925 {source="ISBN10:0073040584"} ! endoderm xref: SCTID:362845002 ! Entire yolk sac xref: http://upload.wikimedia.org/wikipedia/commons/1/17/Gray22.png property_value: external_definition "One of the extraembryonic fetal membranes that balloons out from the fetal midgut. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000830", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/yolk+sac", source="http://bgee.unil.ch/"} property_value: homology_notes "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {external_class="VHOG:0000830", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.187", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0043425 [Term] id: UBERON:0010048 name: Duvernoy's gland def: "A gland situated on the upper lip found in non-venomous snakes. Releases secretion via duct adjacent to posterior maxillary teeth." [ISBN10:0073040584, Wikipedia:Duvernoy's_gland] is_a: UBERON:0010047 ! oral gland disjoint_from: UBERON:0000460 ! major vestibular gland relationship: homologous_to UBERON:0008976 {source="ISBN10:0073040584"} ! venom gland relationship: only_in_taxon NCBITaxon:8578 {source="Wikipedia"} ! Colubridae [Term] id: UBERON:0010049 name: supralabial gland def: "Glandular tissue present in lips of reptiles." [ISBN10:0073040584, Wikipedia:Duvernoy's_gland] is_a: UBERON:0010047 ! oral gland [Term] id: UBERON:0010050 name: infralabial gland def: "Glandular tissue present in lips of reptiles." [ISBN10:0073040584, Wikipedia:Duvernoy's_gland] is_a: UBERON:0010047 ! oral gland [Term] id: UBERON:0001044 name: salivary gland def: "saliva-secreting exocrine glands of the oral cavity[GO]. The salivary glands in mammals are exocrine glands, glands with ducts, that produce saliva. They also secrete amylase, an enzyme that breaks down starch into maltose. In other organisms such as insects, salivary glands are often used to produce biologically important proteins like silk or glues, and fly salivary glands contain polytene chromosomes that have been useful in genetic research[WP]." [GO:0007431, Wikipedia:Salivary_gland] comment: currently we define saliva and salivary glands very generally in functional terms but it may be more appropriate to split this class. From WP: In most vertebrates, saliva does not contain any enzymes, consisting of mucus and water only, and its primary function is to moisten food while eating. As a result, true salivary glands are rarely found in fish or aquatic tetrapods, although there are often individual mucus-secreting cells. Amphibians have a single salivary gland, the intermaxillary gland, located in the forward part of the palate. Reptiles and birds normally have only very small glands on the lips, palate, and base of the mouth, although there are some birds with large glands, which produce a sticky saliva that helps in nest-building. The distinct parotid, submandibular, and sublingual glands are only developed in mammals.[3] The salivary glands of some species, however, are modified to produce enzymes; salivary amylase is found in many, but by no means all, bird and mammal species (including humans, as noted above). Furthermore, the venom glands of poisonous snakes, Gila monsters, and some shrews, are modified salivary glands subset: uberon_slim subset: functional_classification xref: BTO:0001203 xref: EFO:0000859 ! salivary gland xref: EHDAA:7987 ! salivary gland xref: FBbt:00005382 ! salivary gland xref: FMA:9597 ! Salivary gland xref: GAID:937 ! salivary gland xref: VHOG:0000376 ! salivary gland xref: MA:0000346 ! salivary gland xref: MAT:0000079 ! salivary gland xref: MIAA:0000079 ! salivary gland xref: OpenCyc:Mx4rvVjl5ZwpEbGdrcN5Y29ycA xref: ncithesaurus:Salivary_Gland ! Salivary Gland xref: galen:SalivaryGland ! salivary gland xref: OpenCyc:Mx4rvVjl5ZwpEbGdrcN5Y29ycA ! salivary gland xref: EHDAA2:0001775 ! salivary gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/51/Illu_quiz_hn_02.jpg/200px-Illu_quiz_hn_02.jpg xref: EMAPA:17751 ! salivary gland xref: MESH:A10.336.779 ! salivary gland xref: EV:0100059 ! salivary gland is_a: UBERON:0010047 ! oral gland intersection_of: UBERON:0002530 ! gland intersection_of: secretes UBERON:0001836 ! saliva relationship: located_in UBERON:0000167 ! oral cavity relationship: part_of UBERON:0001041 ! foregut xref: SCTID:181236000 ! Entire salivary gland subset: organ_slim synonym: "glandulae salivariae" RELATED LATIN [Wikipedia:Salivary_gland] xref: http://upload.wikimedia.org/wikipedia/commons/5/51/Illu_quiz_hn_02.jpg property_value: external_definition "A gland that produces the saliva. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-25, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000376", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In air-feeding animals, the lack of water column to lubricate the food has been compensated for by the evolution of the salivary glands. These glands are present only in amniotes and are controlled by the parasympathetic system.[well established][VHOG]" xsd:string {external_class="VHOG:0000376", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptationm(2005) p.211", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0036098 [Term] id: UBERON:0002539 name: pharyngeal arch def: "One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches" [NLM:branchial+arch, Wikipedia:Pharyngeal_arch, PMID:16313389] comment: Numbered cranial to caudal. different in mammals. branchial arch = ZFA:0001613 pharyngeal arch 3-7. generally gill arch 1 = pharyngeal arch 3. terminology varies as to whether branchial arch follows gill or pharyngeal numbering subset: uberon_slim subset: vertebrate_core synonym: "pharyngeal arches" EXACT PLURAL [] synonym: "visceral arch" RELATED [] synonym: "branchial arch" NARROW [MP:0002884, BTO:0001785] xref: VHOG:0000155 ! pharyngeal arch xref: MAT:0000242 ! pharyngeal arch xref: MIAA:0000242 ! pharyngeal arch xref: TAO:0001306 ! pharyngeal arch xref: XAO:0000096 ! pharyngeal arch xref: ZFA:0001306 ! pharyngeal arch xref: ncithesaurus:Pharyngeal_Arch ! Pharyngeal Arch xref: EFO:0000959 ! pharyngeal arch xref: BTO:0001785 ! branchial arch xref: XAO:0000096 ! pharyngeal arch xref: AAO:0010359 ! pharyngeal arch xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Gray41.png/200px-Gray41.png xref: EMAPA:16117 ! branchial arch xref: MESH:A16.254.160 ! branchial region xref: GAID:1292 ! branchial region xref: EHDAA:571 ! branchial arch is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata relationship: part_of UBERON:0008814 ! pharyngeal system relationship: part_of UBERON:0008816 {source="PMID:16313389"} ! embryonic head relationship: induced_by UBERON:0007690 {source="PMID:16313389"} ! early pharyngeal endoderm relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest xref: SCTID:308766004 ! Entire branchial arch (also: UBERON:0008896 'post-hyoid pharyngeal arch') synonym: "arcus pharyngei" RELATED LATIN [Wikipedia:Pharyngeal_arch] xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png property_value: external_definition "One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010359", date_retrieved="2012-06-20", source="NLM:branchial+arch"} property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down.[well established][VHOG]" xsd:string {external_class="VHOG:0000155", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0080322 [Term] id: UBERON:0008814 ! pharyngeal system name: pharyngeal system def: "A transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph, GO:0060037] synonym: "pharyngeal apparatus" EXACT [] synonym: "pharyngeal arches and clefts" RELATED [] synonym: "pharyngeal arch region" EXACT [EHDAA2:0000187] xref: EHDAA2:0000187 ! pharyngeal arch region is_a: UBERON:0002050 ! embryonic structure xref: ncithesaurus:Pharyngeal_Apparatus ! Pharyngeal Apparatus xref: UMLS:C1519038 [Term] id: UBERON:0008815 name: pharyngeal slit def: "filter-feeding organs found in non-vertebrate chordates (lancelets and tunicates) and hemichordates living in aquatic environments. These repeated segments are controlled by similar developmental mechanisms." [Wikipedia:Pharyngeal_slit] comment: Editor/Taxon notes: requires review. Kardong uses the term pharyngeal slit for Chondrichthyans. 'branchial slit' may also be used for aminiote structures? is_a: UBERON:0000062 ! organ relationship: has_function_in GO:0007631 ! feeding behavior relationship: never_in_taxon NCBITaxon:7742 ! Vertebrata relationship: only_in_taxon NCBITaxon:7711 ! Chordata subset: organ_slim [Term] id: UBERON:0006562 ! pharynx name: pharynx def: "The pharynx is the part of the digestive system immediately posterior to the mouth[GO]." [GO:0060465] comment: Taxon notes: This is a dubious grouping class that collects structures as diverse as the chordate pharynx (which is a subclass - UBERON:0001042) and the nematode pharynx. This portion of the ontology should be revised, but this should be done in sync with GO, from which this grouping arises subset: uberon_slim subset: grouping_class synonym: "pharyngeal tube" EXACT [] xref: MAT:0000049 ! pharynx xref: MIAA:0000049 ! pharynx xref: WBbt:0003681 ! pharynx xref: FBbt:00005380 ! pharynx is_a: UBERON:0004921 ! subdivision of digestive tract property_value: external_definition "A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} property_value: has_relational_adjective "pharyngeal" xsd:string property_value: has_relational_adjective "branchial" xsd:string [Term] id: UBERON:0009145 name: pharyngeal region is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0001041 {source="EHDAA2"} ! foregut relationship: part_of UBERON:0001557 {source="EHDAA2"} ! upper respiratory tract xref: EMAPA:16549 ! pharyngeal region xref: RETIRED_EHDAA2:0001454 ! pharyngeal region [Term] id: UBERON:0001042 name: chordate pharynx def: "Funnel-shaped fibromuscular tube that conducts food to the esophagus, and air to the larynyx and lungs. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx)[MESH]. Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills[ZFA]." [Wikipedia:Pharynx] comment: Note that MA/FMA pharynx not part of digestive/alimentary system, we follow their lead here subset: uberon_slim subset: vertebrate_core synonym: "pharynx" BROAD SENSU [FMA:46688] xref: BTO:0001049 xref: EFO:0000836 ! pharynx xref: EHDAA:2947 ! pharynx xref: FMA:46688 ! Pharynx xref: GAID:155 ! pharynx xref: VHOG:0000462 ! pharynx xref: MA:0000432 ! pharynx xref: OpenCyc:Mx4rvViv7ZwpEbGdrcN5Y29ycA xref: TAO:0000056 ! pharynx xref: ZFA:0000056 ! pharynx xref: XAO:0003227 ! pharynx xref: ncithesaurus:Pharynx ! Pharynx xref: galen:Pharynx ! pharynx xref: OpenCyc:Mx4rvViv7ZwpEbGdrcN5Y29ycA ! pharynx xref: EHDAA2:0001458 ! pharynx xref: EMAPA:16706 ! pharynx of foregut xref: EMAPA:18838 ! pharynx of gut xref: MESH:A03.867 ! pharynx xref: EV:0100065 ! pharynx xref: AAO:0000967 ! pharynx xref: SCTID:181211006 ! Entire pharynx is_a: UBERON:0006562 ! pharynx relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001004 ! respiratory system relationship: develops_from UBERON:0009145 {source="EHDAA2"} ! pharyngeal region relationship: continuous_with UBERON:0001043 ! esophagus relationship: distally_connected_to UBERON:0001043 ! esophagus property_value: external_definition "Anatomical cavity bounded by the derivatives of the branchial arches.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000967", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: develops_from respiratory system (UBERON:0001004)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000967", date_retrieved="2012-06-20"} property_value: axiom_lost_from_external_ontology "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: part_of respiratory system (UBERON:0001004)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000967", date_retrieved="2012-06-20"} property_value: external_definition "Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000056", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "The portion of the alimentary canal between the mouth and the oesophagus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000462", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the earliest vertebrates possessed unjointed internal and external branchial arches, and musculature encircling the pharynx.[well established][VHOG]" xsd:string {external_class="VHOG:0000462", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) Box essay 13.1 and Box figure I\, p.502-503", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0031354 [Term] id: UBERON:0009143 ! esophageal region name: developing esophageal region comment: consider merging into esophagus synonym: "oesophageal region" BROAD [EMAPA:16700] synonym: "esophageal region" BROAD [] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0001041 {source="EHDAA2"} ! foregut xref: EMAPA:16700 ! oesophageal region xref: RETIRED_EHDAA2:0000654 ! oesophageal region synonym: "oesophageal region" EXACT [RETIRED_EHDAA2:0000654] xref: SCTID:245404000 ! Region of esophagus [Term] id: UBERON:0001043 name: esophagus def: "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." [Wikipedia:Esophagus, http://www.rivm.nl/interspeciesinfo/inter/oesophagus/] comment: AO notes: esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995) subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "gullet" EXACT [] synonym: "oesophagus" EXACT [] xref: AAO:0000145 ! esophagus xref: BTO:0000959 xref: EFO:0000835 ! oesophagus xref: EHDAA:2937 ! oesophagus xref: FMA:7131 ! Esophagus xref: GAID:291 ! esophagus xref: galen:Esophagus xref: VHOG:0000450 ! oesophagus xref: MA:0000352 ! esophagus xref: MAT:0000048 ! oesophagus xref: MIAA:0000048 ! oesophagus xref: ncithesaurus:Esophagus xref: OpenCyc:Mx4rvVj9Q5wpEbGdrcN5Y29ycA xref: TAO:0000204 ! esophagus xref: XAO:0000127 ! esophagus xref: ZFA:0000204 ! esophagus xref: OpenCyc:Mx4rvVj9Q5wpEbGdrcN5Y29ycA ! esophagus xref: EHDAA2:0001285 ! oesophagus xref: EMAPA:16833 ! oesophagus of foregut xref: EMAPA:18860 ! oesophagus of gut xref: MESH:A03.365 ! esophagus xref: EV:0100069 ! oesophagus xref: ANISEED:1235301 ! Esophagus is_a: UBERON:0000062 {source="FMA", source="MA"} ! organ is_a: UBERON:0004921 ! subdivision of digestive tract relationship: located_in UBERON:0002224 ! thoracic cavity relationship: develops_from UBERON:0009143 ! esophageal region relationship: distally_connected_to UBERON:0000945 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="only in species that have a stomach"} ! stomach relationship: proximally_connected_to UBERON:0001042 ! chordate pharynx xref: SCTID:181245004 ! Entire esophagus subset: organ_slim synonym: "œsophagus" RELATED LATIN [Wikipedia:Esophagus] xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg property_value: external_definition "Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000145", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "The few structural specializations in (adult lampreys) pharynx include complex valves on the external gill openings that direct the tidal flow, and the division of the ancestral pharynx into an oesophagus and a respiratory pharynx.[well established][VHOG]" xsd:string {external_class="VHOG:0000450", ontology="VHOG", source="DOI:10.1111/j.1096-3642.1996.tb01658.x Mallatt J\, Ventilation and the origin of jawed vertebrates: a new mouth. Zoological Journal of the Linnean Society (1996)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "esophageal" xsd:string xref: UMLS:C0014876 [Term] id: UBERON:0010039 ! food storage organ name: food storage organ def: "An organ of the digestive tract that is capable of retaining and storing food" [UBERON:cjm] comment: This is a very broad functionally defined grouping class that collects disparate structures from insects to vertebrates subset: grouping_class subset: functional_classification is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0005409 ! gastrointestinal system xref: TADS:0000172 ! adult stomach xref: TGMA:0001041 ! adult stomach [Term] id: UBERON:0000945 name: stomach def: "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." [UBERON:cjm, ISBN10:0073040584, Wikipedia:Stomach] comment: Taxon notes: We restrict this to the vertebrate specific structure - see the grouping class 'food storage organ' for analogous structures in other species. Teleosts: Zebrafish is functionally stomach-less, but may retain ontogenic footprint. Although the precise shape and size of the stomach varies widely among different vertebrates, the relative positions of the oesophageal and duodenal openings remain relatively constant. As a result, the organ always curves somewhat to the left before curving back to meet the pyloric sphincter. However, lampreys, hagfishes, chimaeras, lungfishes, and some teleost fish have no stomach at all, with the oesophagus opening directly into the intestine. The gastric lining is usually divided into two regions, an anterior portion lined by fundic glands, and a posterior with pyloric glands. Cardiac glands are unique to mammals, and even then are absent in a number of species. The distributions of these glands vary between species, and do not always correspond with the same regions as in man. Furthermore, in many non-human mammals, a portion of the stomach anterior to the cardiac glands is lined with epithelium essentially identical to that of the oesophagus. Ruminants, in particular, have a complex stomach, the first three chambers of which are all lined with oesophageal mucosa -- Stomach#In_other_animals subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "anterior intestine" RELATED [] synonym: "mesenteron" RELATED [] synonym: "stomach chamber" NARROW [] synonym: "ventriculus" RELATED [] synonym: "gaster" RELATED [BTO:0001307] xref: AAO:0000579 ! stomach xref: BTO:0001307 xref: EFO:0000837 ! stomach xref: EHDAA:2993 ! stomach xref: FMA:7148 ! Stomach xref: GAID:293 ! stomach xref: VHOG:0000408 ! stomach xref: MA:0000353 ! stomach xref: MAT:0000051 ! stomach xref: MIAA:0000051 ! stomach xref: ncithesaurus:Stomach xref: OpenCyc:Mx4rvVjlqpwpEbGdrcN5Y29ycA xref: TAO:0002121 ! stomach xref: XAO:0000128 ! stomach xref: galen:Stomach ! stomach xref: OpenCyc:Mx4rvVjlqpwpEbGdrcN5Y29ycA ! stomach xref: EHDAA2:0001915 ! stomach xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Stomach_diagram.svg/200px-Stomach_diagram.svg.png xref: EMAPA:17021 ! stomach of foregut xref: EMAPA:18889 ! stomach of gut xref: MESH:A03.492.766 ! stomach xref: EV:0100070 ! stomach xref: ANISEED:1235297 ! Stomach is_a: UBERON:0010039 {source="cjm"} ! food storage organ is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract relationship: part_of UBERON:0001041 ! foregut relationship: capable_of GO:0001696 {evidence="ISBN:0486692132"} ! gastric acid secretion relationship: never_in_taxon NCBITaxon:7955 {source="ZFA"} ! Danio rerio relationship: only_in_taxon NCBITaxon:7776 {source="Kardong", notes="absent in lampreys and hagfishes"} ! Gnathostomata relationship: only_in_taxon NCBITaxon:7742 {source="Wikipedia"} ! Vertebrata xref: SCTID:181246003 ! Entire stomach subset: organ_slim synonym: "Ventricular" RELATED LATIN [Wikipedia:Stomach] xref: http://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg property_value: external_definition "Portion of alimentary canal with increased circular and longitudinal smooth muscle. Bounded posteriorly by the pyloric sphincter. Mucosal lining has increased folding.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000579", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "It appears that the stomach has an ancient origin. The stomach first appears in the fish lineage. The prevertebrate chordates do not have a true stomach, whereas the cartilaginous and bony fish do. Although most fish do have a true stomach, some fish species appear to have lost the stomach secondarily. The remaining vertebrate lineages do have a true stomach (at least in the adult animal), although there is great variation in the size and shape of the stomach.[well established][VHOG]" xsd:string {external_class="VHOG:0000408", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00076.x Smith DM\, Grasty RC\, Theodosiou NA\, Tabin CJ\, Nascone-Yoder NM\, Evolutionary relationships between the amphibian\, avian\, and mammalian stomachs. Evolution and development (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0038351 [Term] id: UBERON:0001007 name: digestive system def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [FB:gg, NLM:alimentary+system, Wikipedia:Digestive_system,] comment: note that many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class subset: uberon_slim subset: vertebrate_core synonym: "alimentary system" RELATED [] synonym: "alimentary tract" RELATED [] synonym: "gastrointestinal system" RELATED [] synonym: "gut" RELATED [] xref: AAO:0000129 ! digestive_system xref: BILA:0000082 xref: FBbt:00005055 ! digestive system xref: FMA:7152 ! Alimentary system xref: GAID:278 ! digestive system xref: galen:DigestiveSystem xref: MA:0002431 ! digestive system xref: MAT:0000018 ! digestive system xref: MIAA:0000018 ! digestive system xref: TAO:0000339 ! digestive system xref: ZFA:0000339 ! digestive system xref: WBbt:0005748 ! alimentary system xref: XAO:0000125 ! alimentary system xref: TADS:0000170 ! adult alimentary system xref: EFO:0000793 ! digestive system component xref: BTO:0000058 ! alimentary canal (also: UBERON:0005409 'gastrointestinal system') xref: MESH:A03 ! digestive system xref: EV:0100056 ! alimentary system (also: UBERON:0005409 'gastrointestinal system') intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0007586 ! digestion disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system xref: ncithesaurus:Digestive_System ! Digestive System xref: SCTID:278859004 ! Entire digestive system property_value: external_definition "An anatomical system consisting of the alimentary canal and digestive glands responsible for intake, absorption, digestion and excretion of food.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000129", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: has_relational_adjective "digestive" xsd:string [Term] id: UBERON:0005409 name: gastrointestinal system comment: note that many anatomy ontologies consider this synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class. We have one entity that is part of both gastrointestinal and hepatobiliary systems: hepatopancreatic ampulla synonym: "alimentary system" RELATED [MA:0000323] synonym: "alimentary tract" RELATED [MA:0000323] synonym: "gastrointestinal tract" RELATED INCONSISTENT [FMA:71132] synonym: "gastro-intestinal system" RELATED [FMA:71132] synonym: "gastrointestinal system" RELATED [FMA:71132] synonym: "GI tract" RELATED [GAID:294] synonym: "gastrointestinal (GI) tract" RELATED [GAID:294] xref: MA:0000323 ! gastrointestinal system xref: EHDAA2:0000110 ! alimentary system xref: EHDAA:514 ! alimentary system xref: VHOG:0000412 ! alimentary system xref: GAID:294 ! gastrointestinal system xref: ncithesaurus:Gastrointestinal_System xref: FMA:71132 ! gastrointestinal tract xref: BTO:0000058 ! alimentary canal (also: UBERON:0001007 'digestive system') xref: EMAPA:16246 ! alimentary system xref: MESH:A03.492 ! gastrointestinal system xref: EV:0100056 ! alimentary system (also: UBERON:0001007 'digestive system') is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0001007 ! digestive system xref: SCTID:373871007 ! Entire gastrointestinal system xref: galen:GastrointestinalTract ! gastrointestinal tract property_value: homology_notes "All metazoans (with degenerate exceptions) have some sort of digestive cavity with a means of entrance to and exit from it.[well established][VHOG]" xsd:string {external_class="VHOG:0000412", ontology="VHOG", source="ISBN:978-0721676685 Sherwood Romer A and Parsons T\, Vertebrate body (1977) p.3", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0012240 [Term] id: UBERON:0002423 ! hepatobiliary system name: hepatobiliary system def: "The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. The parts are: liver, bile duct, gall bladder and hepatic duct" [Wikipedia:Hepatobiliary_system, GO:0061008] subset: uberon_slim subset: vertebrate_core synonym: "hepaticobiliary system" EXACT [GO:0061008] synonym: "liver and biliary system" EXACT [] synonym: "liver/biliary system" RELATED [] xref: EFO:0000800 ! liver and biliary system xref: EHDAA:2189 ! liver and biliary system xref: VHOG:0000294 ! liver and biliary system xref: MA:0000324 ! hepatobiliary system xref: MAT:0000024 ! liver and biliary system xref: MIAA:0000024 ! liver and biliary system xref: TAO:0000036 ! liver and biliary system xref: XAO:0000132 ! liver and biliary system xref: ZFA:0000036 ! liver and biliary system xref: ncithesaurus:Hepatobiliary_System ! Hepatobiliary System xref: EHDAA2:0000998 ! liver and biliary system xref: EMAPA:16840 ! liver and biliary system xref: EV:0100088 ! liver and biliary system xref: AAO:0011056 ! liver and biliary system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system relationship: part_of UBERON:0001007 ! digestive system xref: UMLS:C1711359 property_value: external_definition "System responsible for the production and movement of bile[ZFIN:curator]." xsd:string {source="ZFIN:curator"} [Term] id: UBERON:0001555 name: digestive tract def: "Tube extending from the mouth to the anus." [http://en.wikipedia.org/wiki/Talk:Human_gastrointestinal_tract, http://sourceforge.net/tracker/?func=detail&atid=440764&aid=2991587&group_id=36855] comment: Terminology notes: we following Kardong in naming the entire tube from mouth to anus the alimentary canal. Kardong calls the portion of this tract that excludes buccal cavity and pharynx the 'alimentary canal', consider adding an extra class for this. AO notes: GO says gut is region of DT, from intestines to anus. ZFA treats as synonym for alimentary canal, and treats it as the sum of DT + organs (ZF has no term from stomach). GO says intestines to anus (excludes stomach and esophagus). MA appears to agree with GO (stomach and esophagus are not parts). FMA includes stomach and esophagus as parts of gut -- the FMA divides gut into lower and upper GI tract; it's not clear if this is exhaustive (small intestine is in neither), but lower GI tract may correspond better to the GO definition. NOTE: GO now changed, see sf id in def xref. Note that FMA also has a term 'gastrointestinal tract', but this includes the liver. subset: uberon_slim subset: vertebrate_core synonym: "alimentary canal" NARROW [] synonym: "gut tube" RELATED [] synonym: "digestive tube" EXACT [] synonym: "gut" BROAD [] synonym: "enteric tract" EXACT [ZFA:0000112] xref: BILA:0000083 ! digestive tract xref: BTO:0000545 ! gut xref: EHDAA:518 ! gut xref: FBbt:00003125 ! alimentary canal xref: FMA:45615 ! Gut xref: VHOG:0000309 ! gut xref: OpenCyc:Mx4rvVi0GpwpEbGdrcN5Y29ycA xref: TAO:0000112 ! gut xref: ZFA:0000112 ! gut xref: OpenCyc:Mx4rvVi0GpwpEbGdrcN5Y29ycA ! digestive tract xref: EHDAA2:0000726 ! gut (also: UBERON:0004907 'lower digestive tract') xref: BTO:0000511 ! gastrointestinal tract xref: TGMA:0001819 ! adult alimentary canal xref: EMAPA:16247 ! gut xref: WBbt:0005743 ! digestive tract xref: galen:AlimentaryTract is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001007 ! digestive system relationship: develops_from UBERON:0007026 {source="NBK10107"} ! primitive gut relationship: never_in_taxon NCBITaxon:41324 {source="doi:10.1371/journal.pone.0016309"} ! Siboglinidae relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha xref: AAO:0010023 ! gut tube xref: ncithesaurus:Gastrointestinal_Tract ! Gastrointestinal Tract property_value: external_definition "The alimentary or digestive tract, and associated organs.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000112", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000309", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.203\, ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0017189 [Term] id: UBERON:0004921 ! subdivision of digestive tract name: subdivision of digestive tract comment: intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct. synonym: "subdivision of alimentary system" RELATED [FMA:71131] synonym: "alimentary system subdivision" RELATED [FMA:71131] subset: non_informative xref: FMA:71131 ! Subdivision of alimentary system xref: FBbt:00100315 ! gut section is_a: UBERON:0013522 ! subdivision of tube relationship: part_of UBERON:0001555 ! digestive tract relationship: subdivision_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0004907 name: lower digestive tract def: "the region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]." [Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract] comment: WP: small intestine, large intestine, anus. Anal canal not part of LGIT according to FMA, but anus is considered part of LGIT according to WP. Duodenum overlaps both U/L subset: uberon_slim synonym: "gut" BROAD [GO:0048565] synonym: "lower GI tract" EXACT [] synonym: "lower gastrointestinal tract" EXACT [] xref: MA:0000917 ! gut xref: FMA:49179 ! Lower gastrointestinal tract xref: ncithesaurus:Lower_Gastrointestinal_Tract ! Lower Gastrointestinal Tract xref: galen:LowerGastrointestinalTract ! lower gastrointestinal tract xref: EHDAA2:0000726 ! gut (also: UBERON:0001555 'digestive tract') is_a: UBERON:0004921 ! subdivision of digestive tract relationship: develops_from UBERON:0001046 ! hindgut relationship: part_of UBERON:0005409 ! gastrointestinal system xref: SCTID:279973004 ! Entire lower gastrointestinal tract xref: UMLS:C0226875 [Term] id: UBERON:0004908 name: upper digestive tract def: "the region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum." [Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract] comment: WP: small intestine, large intestine, anus. Anal canal not part of LGIT according to FMA, but anus is considered part of LGIT according to WP. Duodenum overlaps both U/L. In Galen, entire GI tract excludes esophagus subset: uberon_slim synonym: "upper gastrointestinal tract" EXACT [] synonym: "upper GI tract" EXACT [] xref: FMA:49177 ! upper gastrointestinal tract xref: ncithesaurus:Upper_Gastrointestinal_Tract is_a: UBERON:0004921 ! subdivision of digestive tract relationship: develops_from UBERON:0001041 ! foregut xref: galen:UpperGastrointestinalTract xref: SCTID:181244000 ! Entire upper gastrointestinal tract xref: UMLS:C0226874 [Term] id: UBERON:0001041 name: foregut def: "Anterior subdivision of a digestive tract[CJM]. An anterior part of the alimentary canal derived from the ectoderm[WP]." [Wikipedia:Foregut] comment: Editor notes: Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class (as it appears to be in FMA) subset: uberon_slim subset: developmental_classification xref: BILA:0000085 xref: BTO:0000507 xref: EHDAA:520 ! foregut xref: FBbt:00005379 ! foregut xref: FMA:45616 ! Foregut xref: VHOG:0000285 ! foregut xref: MA:0001526 ! foregut xref: XAO:0000232 ! foregut xref: ncithesaurus:Foregut ! Foregut xref: EHDAA2:0000557 ! foregut xref: TGMA:0001014 ! adult foregut xref: EMAPA:16548 ! foregut is_a: UBERON:0004921 ! subdivision of digestive tract xref: AAO:0011042 ! foregut xref: SCTID:361409009 ! primitive foregut synonym: "praeenteron" RELATED LATIN [Wikipedia:Foregut] synonym: "proenteron" RELATED LATIN [Wikipedia:Foregut] xref: http://upload.wikimedia.org/wikipedia/commons/9/9a/Gray27.png property_value: homology_notes "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000285", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.203\, ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231051 [Term] id: UBERON:0001045 name: midgut def: "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]. In humans: originates from the foregut at the opening of the bile duct into the duodenum and continues through the small intestine and much of the large intestine until the transition to the hindgut about two-thirds of the way through the transverse colon. That part of the alimentary canal which lies between the gizzard and the hind intestine." [Wikipedia:Midgut, GO:0007494] comment: Editor notes: Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class. AO Notes: in FMA this class has no children. synonym: "mesenteron" RELATED LATIN [Wikipedia:Midgut] subset: uberon_slim subset: developmental_classification xref: BILA:0000086 xref: BTO:0000863 xref: FMA:45617 ! Midgut xref: VHOG:0000290 ! midgut xref: MA:0001564 ! midgut xref: XAO:0000103 ! midgut xref: ncithesaurus:Midgut ! Midgut xref: EFO:0001950 ! midgut xref: EHDAA:983 ! midgut xref: FBbt:00005383 ! midgut xref: EHDAA2:0001185 ! midgut xref: TGMA:0001036 ! adult midgut xref: EMAPA:16255 ! midgut is_a: UBERON:0004921 ! subdivision of digestive tract relationship: proximally_connected_to UBERON:0001041 ! foregut xref: SCTID:361410004 ! primitive midgut xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg property_value: homology_notes "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000290", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.203\, ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231052 [Term] id: UBERON:0001046 name: hindgut def: "Posterior subdivision of a digestive tract[CJM]." [Wikipedia:Hindgut] comment: Editor notes: Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - UBERONREF:0000002). We may explicitly make this a developmental class. AO Notes: in FMA this class has no children. subset: uberon_slim subset: developmental_classification xref: BILA:0000087 xref: BTO:0000510 xref: FBbt:00005384 ! hindgut xref: FMA:45618 ! Hindgut xref: VHOG:0000459 ! hindgut xref: MA:0001527 ! hindgut xref: XAO:0000104 ! hindgut xref: ncithesaurus:Hindgut ! Hindgut xref: EHDAA:975 ! hindgut xref: EHDAA2:0000779 ! hindgut xref: TGMA:0001020 ! adult hindgut xref: EMAPA:16715 ! hindgut is_a: UBERON:0004921 ! subdivision of digestive tract relationship: proximally_connected_to UBERON:0001045 ! midgut relationship: develops_from UBERON:0003104 {source="Wikipedia"} ! mesenchyme xref: AAO:0011052 ! hindgut xref: SCTID:362856002 ! Entire hindgut synonym: "metenteron" RELATED LATIN [Wikipedia:Hindgut] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png property_value: homology_notes "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000459", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.203\, ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231053 [Term] id: UBERON:0011698 name: midgut loop def: "Portion of midgut after it bends around the superior mesenteric artery" [Wikipedia:Wikipedia] is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0001045 {source="VHOG"} ! midgut xref: VHOG:0000673 ! midgut loop xref: ncithesaurus:Midgut_Loop ! midgut loop xref: EMAPA:17036 ! loop xref: UMLS:C1513298 [Term] id: UBERON:0009890 name: anterior intestinal portal synonym: "fovea cardiaca" EXACT [http://www.drugs.com/dict/fovea-cardiaca.html] def: "opening of the foregut into the midgut" [http://www.drugs.com/dict/fovea-cardiaca.html] is_a: UBERON:0004111 ! anatomical conduit relationship: adjacent_to UBERON:0001041 ! foregut relationship: adjacent_to UBERON:0001046 ! hindgut [Term] id: UBERON:0004906 name: ectodermal gut def: "A portion of the gut that is derived from ectoderm." [GO:0007439] intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001555 ! digestive tract intersection_of: develops_from UBERON:0000924 ! ectoderm [Term] id: UBERON:0004185 name: endodermal gut def: "A portions of the gut that is derived from endoderm." [GO:0061031] intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001555 ! digestive tract intersection_of: develops_from UBERON:0000925 ! endoderm [Term] id: UBERON:0004163 name: anterior ectodermal midgut def: "portions of the midgut that are derived from ectoderm." [GO:0007441] is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0000924 ! ectoderm [Term] id: UBERON:0000100 name: blastopore def: "Structure around the opening into the archenteron during the embryonic stages of an organism. The distinction between protostomes and deuterostomes is based on the direction in which the mouth (stoma) develops in relation to the blastopore." [Wikipedia:Blastopore] comment: In protostome development, the first opening in development, the blastopore, becomes the animal's mouth; In deuterostome development, the blastopore becomes the animal's anus subset: metazoa_core xref: XAO:0000208 ! blastopore xref: BTO:0001695 ! blastopore xref: AAO:0000045 ! blastopore is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004735 ! archenteron relationship: homologous_to FBbt:00000123 {source="vVHOG:0001202"} ! amnioproctodeal invagination relationship: dubious_for_taxon NCBITaxon:7955 {source="http://zfin.org/zf_info/zfbook/stages/gast.html"} ! Danio rerio subset: early_development property_value: external_definition "A slit-like invagination on the dorsal side of the blastula surface of the embryo where the mesoderm and endoderm move inside the embryo at gatrulation.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000045", date_retrieved="2012-06-20", source="AAO:BJB"} [Term] id: UBERON:0004879 ! marginal zone of embryo name: marginal zone of embryo def: "Belt-like region of presumptive mesoderm at the equator of the late blastula." [XAO:0000068, http://purl.obolibrary.org/obo/uberon/tracker/153] comment: See tracker item for discussion synonym: "marginal zone" BROAD [XAO:0000068] synonym: "margin" BROAD [ZFA:0000038] xref: XAO:0000068 ! marginal zone xref: ZFA:0000038 ! margin is_a: UBERON:0002050 ! embryonic structure subset: early_development xref: AAO:0010448 ! marginal zone xref: TAO:0000038 ! margin synonym: "margins" RELATED PLURAL [TAO:0000038] [Term] id: UBERON:0009888 name: Koller's sickle def: "a local thickening of cells that acts as a margin separating sheets of cells from posterior margin of avian blastoderms from hypoblasts as they migrate anteriorly to push primary hypoblast cells anteriorly to form a secondary hypoblast known as the endoblast" [Wikipedia:Koller's_sickle, PMID:9693154] synonym: "Kohler's sickle" EXACT [] is_a: UBERON:0002050 ! embryonic structure subset: early_development [Term] id: UBERON:0002541 name: germ ring def: "The thickend rim of the blastoderm evident during late blastula and gastrula stages[FishBase]. Embryonic structure which is a uniform thickened annulus at the blastoderm margin, consisting of two layers in addition to the EVL, the epiblast and the hypoblast. The germ ring is formed by the involution of the blastoderm back upon itself[ZFA]" [http://www.fishbase.org/glossary/Glossary.php?q=germ%20ring] comment: todo - check timing of appearance and disappearance - check relationship with primitive streak. he blastopore lips in amphibians appear to have the equivalent function of the germ ring in zebrafish (ES) xref: AAO:0000211 ! germ_ring xref: MAT:0000255 ! germ ring xref: MIAA:0000255 ! germ ring xref: TAO:0000111 ! germ ring xref: ZFA:0000111 ! germ ring xref: EFO:0003427 ! germ ring is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004734 ! gastrula relationship: dubious_for_taxon NCBITaxon:40674 ! Mammalia subset: early_development property_value: external_definition "Embryonic structure that forms as a thickened annulus at the blastoderm rim. The germ ring is thickened because it is the involuting margin of the blastoderm[ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"} [Term] id: UBERON:0003062 ! primitive knot name: primitive knot alt_id: UBERON:0004018 def: "organizer for gastrulation in vertebrates. The primitive knot starts as a regional knot of cells that forms on the blastodisc immediately anterior to where the outer layer of cells will begin to migrate inwards - an area known as the primitive streak. Posterior to the node is the primitive pit, where the cells of the epiblast (the upper layer of embryonic cells) initially begin to invaginate. This invagination expands posteriorly into the primitive groove as the cells layers continue to move into the space between the embryonic cells and the yolk. This differentiates the embryo into the germ layers - endoderm, mesoderm, and ectoderm. The primitive knot migrates posteriorly as gastrulation proceeds, eventually being absorbed into the tail bud.[WP]. the regional thickening of cells at the rostral tip of the vertebrate primitive streak through which gastrulating cells migrate anteriorally to form tissues in the future head and neck; this region organizes the formation of the three embryonic layers and establishes the longitudinal axis and the polarity of the embryo[MP]." [Wikipedia:Primitive_knot, Wikipedia:Regional_specification#Dorsal.2Fventral_axis_.26_organizer, MP:0004066] comment: This class groups together possibly disparate structures, following homology class in vHOG; early development terms need review subset: uberon_slim synonym: "Spemann Mangold organizer" EXACT SENSU [ZFA:0000071] synonym: "Spemann's organizer" EXACT SENSU [ZFA:0000071] synonym: "organizer" EXACT [ZFA:0000071] synonym: "shield" EXACT [ZFA:0000071] synonym: "embryonic shield" EXACT [http://zfin.org/zf_info/zfbook/stages/gast.html] synonym: "dorsal marginal zone" RELATED [XAO:0000072] synonym: "embryonic organizer" EXACT [GAID:1312] synonym: "embryo organizer" EXACT [GAID:1312] synonym: "Hensen node" EXACT SENSU [GAID:1312, Wikipedia:Primitive_knot] synonym: "Hensen's node" EXACT SENSU [GAID:1312, Wikipedia:Primitive_knot] synonym: "primitive node" EXACT [Wikipedia:Primitive_knot] synonym: "DMZ" RELATED [VHOG:0000598] synonym: "node" BROAD [EMAPA:16075, ISBN:9780878932504] xref: EHDAA:549 ! primitive node xref: ncithesaurus:Primitive_Node ! Primitive Node xref: EHDAA2:0001272 ! primitive node xref: EMAPA:16075 ! node xref: BILA:0000053 ! organizer xref: BTO:0003395 ! Spemanns organizer xref: GAID:1312 ! embryonic organizer xref: TAO:0000071 ! shield xref: XAO:0000072 ! dorsal marginal zone xref: ZFA:0000071 ! shield xref: AAO:0000346 ! organizer xref: VHOG:0000598 ! organizer xref: MESH:A16.254.650 ! embryonic organizer is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance relationship: part_of UBERON:0002541 {source="ZFA"} ! germ ring relationship: part_of UBERON:0004341 {source="EHDAA"} ! primitive streak relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata subset: early_development xref: SCTID:361464001 ! Primitive node relationship: develops_from UBERON:0007283 {evidence="definitional"} ! presumptive shield synonym: "nodus primitivus" RELATED LATIN [Wikipedia:Primitive_knot] property_value: external_definition "A signaling center that directs the development of the whole embryo or of part of the embryo.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000346", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "The organizer is a central feature of vertebrate embryogenesis. It was first characterized in functional terms in amphibians by Spemann and Mangold (1924), and homologous tissues have since been identified in representatives of most other vertebrate classes, including mammals (the node), birds (Henson's node) and teleost fish (the embryonic shield).[well established][VHOG]" xsd:string {external_class="VHOG:0000598", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00073.x Neidert AH\, Panopoulou G and Langeland JA\, Amphioxus goosecoid and the evolution of the head organizer and prechordal plate. Evolution and Development (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1283999 property_value: external_definition "Embryonic structure that is a local accumulation of cells along the germ ring. The shield marks the dorsal side of the embryo[ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"} [Term] id: UBERON:0004341 ! primitive streak name: primitive streak def: "The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP]" [MP:0002231, Wikipedia:Primitive_streak] comment: AO notes: VHOG includes a very broad grouping here based on PMID:9609826 xref: EMAPA:16072 ! primitive streak xref: ncithesaurus:Primitive_Streak ! Primitive Streak xref: EHDAA2:0001525 ! primitive streak xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f4/Gray13.png/200px-Gray13.png xref: EHDAA:185 ! primitive streak xref: VHOG:0001202 ! primitive streak - blastopore - amnioproctodeal invagination is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium relationship: part_of UBERON:0000922 {source="EHDAA2"} ! embryo relationship: develops_from UBERON:0008780 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="ISBN:9780878932504"} ! inner cell mass derived epiblast relationship: develops_into UBERON:0000925 ! endoderm relationship: develops_into UBERON:0000926 ! mesoderm relationship: dubious_for_taxon NCBITaxon:32443 ! Teleostei subset: early_development xref: SCTID:361438007 ! Primitive streak xref: http://upload.wikimedia.org/wikipedia/commons/f/f4/Gray13.png synonym: "primitive streak - blastopore - germ ring" EXACT [VHOG:0001202] property_value: homology_notes " (...) the blastopore equivalent of chordates (germ ring in fish, marginal zone/blastopore lip in frog and node/primitive streak in chick and mouse) (...) (reference 1); Indeed, the primitive streak has been considered the homologue of the blastopore since the 1870s (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001202", ontology="VHOG", source="PMID:9609826 Wu LH\, Lengyel JA\, Role of caudal in hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore. Development (1998)\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.139", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0033153 [Term] id: UBERON:0002532 name: epiblast (generic) def: "In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]" [Wikipedia:Epiblast, ZFIN:curator] comment: MP says - tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper. In HOG, epiblast is part of primitive streak/blastpore, which is inconsistent with the MP definition of primitive streak as a ridge of the epiblast. Note that these terms, epiblast and hypoblast, are also used to describe layers of the avian embryonic blastoderm, but the layers so-named seem to be altogether different in these two kinds of vertebrate embryos(CVS). Consider obsoleting this as a grouping class subset: uberon_slim subset: grouping_class subset: vertebrate_core synonym: "epiblast" EXACT [VHOG:0000243] synonym: "blastocyst" RELATED [] synonym: "primitive ectoderm" RELATED [VHOG:0000243] synonym: "ectoblast" RELATED [MP:0003886] xref: VHOG:0000243 ! epiblast xref: MAT:0000067 ! epiblast xref: MIAA:0000067 ! epiblast xref: BTO:0004593 ! epiblast is_a: UBERON:0002050 ! embryonic structure relationship: has_part CL:0000352 ! epiblast cell subset: early_development synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png property_value: homology_notes "In pregastrula zebrafish embryos, the epiblast is an inverted cup of cells that sits on top of a large yolk cell. (...) In amniote embryos (mammals and birds), gastrulation initiates in an epithelial layer called the epiblast. Cells in the epiblast undergo an epithelial to mesenchymal transition (EMT), migrate through the primitive streak (PS), and incorporate in the middle (mesoderm) or outer (endoderm) layer. The presumptive definitive endoderm (DE) cells invade and displace an outer layer of extraembryonic tissue cells, the hypoblast in chick and the visceral endoderm (VE) in mouse, which form supporting structures such as the yolk sac.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000243", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.042308.113344 Zorn AM\, Wells JM\, Vertebrate endoderm development and organ formation. Annual Review of Cell Developmental Biology (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0008780 name: inner cell mass derived epiblast synonym: "embryonic epiblast" RELATED [MP:0003886] intersection_of: UBERON:0002532 ! epiblast intersection_of: develops_from UBERON:0000087 ! inner cell mass relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass relationship: part_of UBERON:0000091 ! bilaminar disc xref: EMAPA:16050 ! epiblast xref: EHDAA2:0000444 ! epiblast xref: EHDAA:42 ! epiblast xref: EHDAA:75 ! epiblast xref: ncithesaurus:Epiblast ! Epiblast subset: early_development def: "An epiblast (generic) that develops_from a inner cell mass." [OBOL:automatic] xref: UMLS:C1516906 [Term] id: UBERON:0008781 name: blastodisc derived epiblast comment: part of blastodisc in BTO; indirect development in ZFA: df DEL df deep blastomere isa blastomere po blastodisc intersection_of: UBERON:0002532 ! epiblast intersection_of: develops_from UBERON:0004749 ! blastodisc relationship: develops_from UBERON:0004749 {source="Wikipedia"} ! blastodisc relationship: part_of UBERON:0002541 {source="ZFA"} ! germ ring xref: TAO:0000018 ! epiblast xref: ZFA:0000018 ! epiblast relationship: dubious_for_taxon NCBITaxon:40674 ! Mammalia subset: early_development property_value: external_definition "The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000018", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass embryonic structure (VSAO:0000178) CHANGED TO: develops_from embryonic structure (UBERON:0002050)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000018", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass embryonic structure (VSAO:0000178) CHANGED TO: part_of embryonic structure (UBERON:0002050)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000018", date_retrieved="2012-08-14"} def: "An epiblast (generic) that develops_from a blastodisc." [OBOL:automatic] [Term] id: UBERON:0007026 ! primitive gut name: primitive gut comment: The endodermal cells generate only the lining of the digestive tube and its glands; mesodermal mesenchyme cells will surround this tube to provide the muscles for peristalsis[NBK10107] xref: BILA:0000084 ! primitive gut xref: ncithesaurus:Primordial_Gut ! primordial gut is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000925 ! endoderm relationship: develops_into UBERON:0001555 ! digestive tract relationship: existence_starts_during UBERON:0000109 ! gastrula stage xref: SCTID:360394002 ! Primitive gut region xref: UMLS:C1514442 [Term] id: UBERON:0004735 ! archenteron name: archenteron def: "The cavity of a gastrula forming a primitive gut[BTO]. The primitive gut that forms during gastrulation in the developing blastula. It develops into the digestive tract of an animal. As primary mesenchyme cells detach from the vegetal pole in the blastula and enter the fluid filled cavity in the center (the blastocoel), the remaining cells at the vegetal pole flatten to form a vegetal plate. This buckles inwards towards the blastocoel in a process called invagination. The cells continue to be rearranged until the shallow dip formed by invagination transforms into a deeper, narrower pouch formed by the gastrula's endoderm. This narrowing and lengthening of the archenteron is driven by convergent extension. The open end of the archenteron is called the blastopore. The filopodia--thin fibers formed by the mesenchyme cells--found in a late gastrula contract to drag the tip of the archenteron across the blastocoel. The endoderm of the archenteron will fuse with the ectoderm of the blastocoel wall. At this point gastrulation is complete, and the gastrula has a functional digestive tube. The indentation that is actually formed is called the lip of the blastopore in amphibians and fish, and the primitive streak in birds and mammals. Each is controlled by the dorsal blastopore, and primitive node (also known as Hensen's node), respectively." [Wikipedia:Archenteron] synonym: "gastrocoel" RELATED [XAO:0000092] synonym: "mesenteron" RELATED [UBERON:cjm] xref: BTO:0001696 ! archenteron xref: XAO:0000092 ! archenteron is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0007026 ! primitive gut relationship: part_of UBERON:0004734 ! gastrula relationship: dubious_for_taxon NCBITaxon:7955 {source="http://zfin.org/zf_info/zfbook/stages/gast.html"} ! Danio rerio xref: AAO:0010430 ! archenteron [Term] id: UBERON:0000930 name: stomodeum def: "Anterior part of the embryonic alimentary canal formed as an invagination of the ectoderm; the future mouth[ZFA]. In humans, a depression between the brain and the pericardium in an embryo, and is the precursor of the mouth and the anterior lobe of the pituitary gland. The stomodeum is lined by ectoderm, and is separated from the anterior end of the fore-gut by the buccopharyngeal membrane. This membrane is devoid of mesoderm, being formed by the apposition of the stomodeal ectoderm with the fore-gut endoderm; at the end of the third week it disappears, and thus a communication is established between the mouth and the future pharynx[WP]. The anterior part of the embryonic digestive system deriving from the stomodeal invagination of the ectoderm[FBbt]." [Wikipedia:Stomodeum] comment: Editor note: consider indicating location. e.g. anterior. Note some AOs place this as part of oral opening, but it's not clear when this structure comes into existence. Taxon note: This class groups together disparate structures as all being the anterior part of the early metazoan digestive tract and precursor of the mouth. However, the developmental processes vary, so this class may be split in future. E.g. in mammals it is a rostral depression surrounded by prominences. Outgrowth of the prominences produces a stomodeal cavity. subset: uberon_slim subset: grouping_class subset: vertebrate_core synonym: "primitive oral cavity" EXACT [UBERON:cjm] synonym: "stomodaeum" EXACT [] synonym: "stomatodeum" EXACT [Wikipedia:Stomodeum] synonym: "mouth primordium" EXACT [XAO:0000269] xref: FBbt:00000439 ! stomodeum xref: ZFA:0001290 ! stomodeum xref: EMAPA:16263 ! stomatodaeum xref: XAO:0000269 ! mouth primordium xref: ncithesaurus:Stomodeum ! Stomodeum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/93/Gray977.png/200px-Gray977.png xref: TGMA:0000135 ! adult stomodeum xref: BTO:0004224 ! stomodeum is_a: UBERON:0003102 {source="ZFA"} ! surface structure relationship: part_of UBERON:0007026 ! primitive gut relationship: part_of UBERON:0000924 ! ectoderm xref: EHDAA2:0001929 ! stomatodaeum xref: TAO:0001290 ! stomodeum xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png property_value: external_definition "Anterior part of the embryonic alimentary canal formed as an invagination of the ectoderm; the future mouth.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001290", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "stomodeal" xsd:string xref: UMLS:C1514977 [Term] id: UBERON:0009715 name: stomodeal cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: part_of UBERON:0000930 ! stomodeum def: "An anatomical cavity that surrounded_by a stomodeum." [OBOL:automatic] [Term] id: UBERON:0000931 ! proctodeum name: proctodeum def: "Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage[ZFA]. A proctodeum is the back ectodermal part of an alimentary canal. It is created during embryogenesis by a folding of the outer body wall[WP]." [Wikipedia:Proctodeum] comment: removed WBbt:0006795 - junction between the alimentary and genital tracts in the male. subset: uberon_slim synonym: "proctodaeum" EXACT [] synonym: "embryonic proctodaeum" EXACT [] xref: FBbt:00000440 xref: VHOG:0000139 ! proctodeum xref: XAO:0001019 ! proctodeum xref: AAO:0011087 ! proctodeum xref: ncithesaurus:Proctodeum ! Proctodeum xref: ZFA:0000066 ! proctodeum xref: VHOG:0000139 ! proctodeum xref: TAO:0000066 ! proctodeum xref: EHDAA2:0000121 ! anal pit is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0007026 ! primitive gut relationship: develops_from UBERON:0000924 ! ectoderm relationship: develops_into UBERON:0001353 ! anal region xref: AAO:0011087 ! proctodeum property_value: external_definition "Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011087", date_retrieved="2012-06-20", source="ZFA:0000066"} property_value: external_definition "An inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000066", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "anal pit" RELATED [VHOG:0000139] property_value: has_relational_adjective "proctodeal" xsd:string xref: UMLS:C0231054 [Term] id: UBERON:0001245 name: anus def: "Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts." [Wikipedia:Anus, ZFIN:curator] comment: Taxon notes: In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html subset: uberon_slim synonym: "opening of terminal part of digestive tract" EXACT [] synonym: "anal orifice" EXACT [] synonym: "anal opening" EXACT [] synonym: "proctodeum" RELATED [] xref: FMA:15711 ! Anus xref: GAID:312 ! anus xref: galen:Anus xref: MA:0000331 ! anus xref: OpenCyc:Mx4rvVjaEZwpEbGdrcN5Y29ycA xref: WBbt:0005364 ! anus xref: FBbt:00003148 ! adult anus xref: FBbt:00001893 ! larval anus xref: TADS:0000066 ! adult anus xref: BTO:0001680 ! anus xref: TGMA:0001279 ! anus xref: OpenCyc:Mx4rvVjaEZwpEbGdrcN5Y29ycA ! anus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/75/Anorectum.gif/200px-Anorectum.gif xref: MESH:A03.492.411.495.767.288 ! anus xref: EV:0100082 ! anus intersection_of: UBERON:0000161 ! orifice intersection_of: distal_part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0000931 ! proctodeum xref: ncithesaurus:Anus ! Anus xref: SCTID:181262009 ! Entire anus xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Protovsdeuterostomes.svg property_value: has_relational_adjective "anal" xsd:string xref: UMLS:C0003461 [Term] id: UBERON:0000165 name: mouth def: "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes teeth, gums, lips, tongue and parts of the palate." [Wikipedia:Mouth, http://purl.obolibrary.org/obo/uberon/references/reference_0000034] comment: AO notes: in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "regio oralis" EXACT [BTO:0004698] synonym: "stoma" RELATED [] synonym: "adult mouth" EXACT [] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral vestibule" RELATED [BTO:0001090] synonym: "rima oris" RELATED [BTO:0001090] synonym: "vestibule of mouth" RELATED [BTO:0001090] synonym: "vestibulum oris" RELATED [BTO:0001090] synonym: "stomatodaeum" RELATED [VHOG:0000812] synonym: "regio oralis" EXACT LATIN [FMA:TA, FMA:49184] synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] synonym: "oral region" RELATED [EHDAA2:0001326] xref: BTO:0001090 xref: EFO:0000825 ! mouth xref: FMA:49184 ! Mouth xref: GAID:75 ! mouth xref: VHOG:0000812 ! mouth xref: MA:0002474 ! mouth xref: MAT:0000038 ! mouth xref: MIAA:0000038 ! mouth xref: OpenCyc:Mx4rvVidh5wpEbGdrcN5Y29ycA xref: TAO:0000547 ! mouth xref: XAO:0003029 ! mouth xref: ZFA:0000547 ! mouth xref: galen:Mouth ! mouth xref: OpenCyc:Mx4rvVidh5wpEbGdrcN5Y29ycA ! mouth xref: http://upload.wikimedia.org/wikipedia/commons/thumb/0/06/Mouth_illustration-Otis_Archives.jpg/180px-Mouth_illustration-Otis_Archives.jpg xref: http://purl.obolibrary.org/obo/uberon/images/lamprey_sucker_rosava_3238889218.jpg xref: TGMA:0000131 ! adult mouth (also: UBERON:0000166 'oral opening') xref: MESH:A01.456.505.631 ! mouth xref: FBbt:00003126 ! adult mouth xref: TADS:0000040 ! adult mouth xref: EHDAA2:0001326 ! oral region xref: MA:0000341 ! oral region xref: VHOG:0000280 ! oral region xref: TAO:0000590 ! oral region xref: ZFA:0000590 ! oral region xref: EHDAA:542 ! oral region xref: EMAPA:16262 ! oral region xref: BTO:0004698 ! regio oralis intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: proximal_part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0000033 ! head relationship: develops_from UBERON:0000930 ! stomodeum relationship: overlaps UBERON:0001004 {notes="exceptions in some taxa"} ! respiratory system xref: AAO:0010355 ! mouth property_value: external_definition "Cavity in which food is initially ingested and generally contains teeth, tongue and glands.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010355", date_retrieved="2012-06-20", source="AAO:BJB"} xref: SCTID:21082005 ! Entire mouth region property_value: homology_notes "Molecular and developmental cell lineage data suggest that the acoel mouth opening is homologous to the mouth of protostomes and deuterostomes and that the last common ancestor of the Bilateria (the 'urbilaterian') had only this single digestive opening.[well established][VHOG]" xsd:string {external_class="VHOG:0000812", ontology="VHOG", source="DOI:10.1038/nature07309 Hejnol A\, Martindale MQ\, Acoel development indicates the independent evolution of the bilaterian mouth and anus. Nature (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "oral" xsd:string [Term] id: UBERON:0000166 name: oral opening def: "The orifice that connects the mouth to the exterio of the body." [http://purl.obolibrary.org/obo/uberon/references/reference_0000034] subset: uberon_slim subset: vertebrate_core synonym: "mouth" RELATED INCONSISTENT [] synonym: "oral part of face" RELATED [] synonym: "subdivision of mouth" RELATED [] synonym: "oral fissure" EXACT [FMA:59806] synonym: "oral orifice" EXACT [FMA:59806] xref: FMA:59806 ! Oral opening is_a: UBERON:0000161 {source="FMA"} ! orifice relationship: part_of UBERON:0000165 ! mouth relationship: overlaps UBERON:0001004 ! respiratory system property_value: homology_notes " (...) mouth development is very similar in protostomes and 'basal' deuterostomes, whereas the chordate mouth seems to develop at a new position. Recent data for echinoderms and hemichordates further suggest that this change in mouth position may result from change in the influence of a conserved ectodermal patterning system on mouth development. It has been suggested that the mouths of vertebrates and urochordates may constitute a 'new' mouth.[well established][VHOG]" xsd:string {external_class="VHOG:0000280", ontology="VHOG", source="DOI:10.1016/j.semcdb.2007.06.002 Christiaen L\, Jaszczyszyn Y\, Kerfant M\, Kanob S\, Thermes V\, Joly JS\, Evolutionary modification of mouth position in deuterostomes. Seminars in Cell and Developmental Biology (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000167 name: oral cavity def: "Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present)" [UBERON:cjm, ISBN10:0073040584, http://purl.obolibrary.org/obo/uberon/references/reference_0000034] subset: uberon_slim subset: vertebrate_core synonym: "cavity of mouth" EXACT [] synonym: "buccal cavity" EXACT [FMA:20292, ISBN10:0073040584] synonym: "bucca" RELATED [] xref: AAO:0000053 ! buccal_cavity xref: EHDAA:6970 ! oral cavity xref: FMA:20292 ! Oral cavity xref: HAO:0000669 ! oral cavity xref: VHOG:0000188 ! oral cavity xref: TAO:0001027 ! oral cavity xref: WBbt:0005255 ! buccal cavity xref: XAO:0000126 ! oral cavity xref: ZFA:0001027 ! oral cavity xref: ncithesaurus:Oral_Cavity ! Oral Cavity xref: EFO:0001975 ! obsolete_oral cavity xref: EHDAA2:0001324 ! oral cavity xref: TGMA:0000102 ! adult cibarium xref: EMAPA:17411 ! oral cavity xref: EMAPA:18399 ! cavity of oral region xref: EV:0100057 ! oral cavity is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0000165 ! mouth relationship: part_of UBERON:0000165 ! mouth xref: AAO:0000960 ! buccal cavity xref: SCTID:181220002 ! Entire oral cavity property_value: external_definition "Anatomical cavity bounded anteriorly by the mouth and posteriorly by the derivatives of the branchial arches.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000960", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "The cavity of the mouth, bounded by the jaw bones and associated structures (muscles and mucosa). [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000188", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/oral+cavity", source="http://bgee.unil.ch/"} property_value: homology_notes "Echinoderms, hemichordates, and chordates are called deuterostomes because the mouth arises not from the blastopore but from a second invagination at the anterior end of the larva that pushes in to connect with the archenteron.[well established][VHOG]" xsd:string {external_class="VHOG:0000188", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.32", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0226896 [Term] id: UBERON:0011640 name: palatoglossal arch def: "A fold that lies between the mouth and pharynx and marks the posterior border of the mouth" [ISBN10:0073040584, Wikipedia:Palatoglossal_arch] synonym: "anterior pillar of fauces" EXACT [FMA:55024] synonym: "glossopalatine arch" EXACT [FMA:55024] synonym: "plica anterior faucium" EXACT LATIN [FMA:TA] synonym: "arcus palatoglossus" EXACT [Wikipedia:Palatoglossal_arch] synonym: "arcus glossopalatinus" EXACT [Wikipedia:Palatoglossal_arch] is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: adjacent_to UBERON:0000165 ! mouth relationship: adjacent_to UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001555 ! digestive tract xref: FMA:55024 ! palatoglossal arch xref: SCTID:276958001 ! Entire anterior pillar of fauces [Term] id: UBERON:0004022 ! embryonic neuroepithelium name: embryonic neuroepithelium def: "the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [MP:0004261] synonym: "neurepithelium" BROAD [BTO:0000314] synonym: "neuroepithelium" EXACT [AEO:0001008] xref: BTO:0000314 ! neuroepithelium xref: EHDAA2:0004654 ! neuroepithelium xref: AEO:0001008 ! neuroepithelium is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0001049 ! neural tube [Term] id: UBERON:0000076 name: external ectoderm def: "The surface ectoderm (or external ectoderm forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis [WP,unvetted]." [Wikipedia:External_ectoderm] comment: Editor note: merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube). synonym: "surface ectoderm" EXACT [] xref: FMA:87656 ! Surface ectoderm xref: ncithesaurus:Surface_Ectoderm ! Surface Ectoderm xref: EHDAA:1494 ! surface ectoderm xref: EHDAA:350 ! surface ectoderm xref: EHDAA:4784 ! surface ectoderm xref: EHDAA:4790 ! surface ectoderm xref: EHDAA:4796 ! surface ectoderm xref: EHDAA:7860 ! surface ectoderm xref: EHDAA2:0001968 ! surface ectoderm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1d/Ectoderm.png/200px-Ectoderm.png xref: EMAPA:16096 ! surface ectoderm of ectoderm of embryo xref: EMAPA:16539 ! surface ectoderm of optic eminence (also: UBERON:0005216 'optic eminence surface ectoderm') is_a: UBERON:0000923 ! germ layer relationship: part_of UBERON:0000924 ! ectoderm xref: UMLS:C1515087 [Term] id: UBERON:0005497 name: non-neural ectoderm subset: vertebrate_core comment: Development notes: After gastrulation, neural crest cells are specified at the border of the neural plate and the non-neural ectoderm. Editor note: todo - epidermis? todo - track down EHDAA2 class in new release // Gene notes: One of the first genes to be expressed in nonneural ectoderm in amphioxus is BMP2/4 (Panopoulou et al. 1998). BMP2/4 homologues appear to have a very ancient role in distinguishing neural from nonneural ectoderm; in Drosophila as well as in amphioxus and vertebrates, BMP2/4 homologues are expressed in nonneural ectoderm and function in distinguishing neural from nonneural ectoderm (Francois & Bier, 1995 ; Sasai et al. 1995 ; Wilson & Hemmati-Brivanlou, 1995; Panopoulou et al. 1998). A change in level of BMP2/4 from very high in nonneural ectoderm to low in neural ectoderm appears to be a key factor in development of neural crest (Baker & Bronner-Fraser,1997a,1997b;Erickson&Reedy,1998;Marchantet al.1998 ;Selleck et al. 1998) synonym: "surface ectoderm" RELATED [UBERONREF:0000002] synonym: "epithelial ectoderm" NARROW [UBERONREF:0000002] synonym: "epidermal ectoderm" NARROW [UBERONREF:0000002] synonym: "ventral ectoderm" EXACT [ZFA:0001178] synonym: "non neural ectoderm" EXACT [ZFA:0001178] xref: ZFA:0001178 ! non neural ectoderm xref: RETIRED_EHDAA2:0001273 ! non-neural ectoderm xref: EMAPA:16074 ! non-neural ectoderm xref: VHOG:0001372 ! non neural ectoderm xref: EHDAA:257 ! non-neural ectoderm xref: EFO:0003643 ! non neural ectoderm is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: develops_from UBERON:0000924 {source="UBERONREF:0000002"} ! ectoderm relationship: spatially_disjoint_from UBERON:0002346 ! neural ectoderm xref: XAO:0004091 ! non-neural ectoderm xref: TAO:0001178 ! non neural ectoderm property_value: homology_notes "In the early gastrula of vertebrates, factors from the organizer (e.g. noggin, chordin, and follistatin in Xenopus) antagonize the epidermalizing factor bone morphogenetic protein 4 (BMP4), thus dividing the epiblast into neuroectoderm. In Drosophila, decapentaplegic, the homologue of BMP4, interacts similarly with the protein short gastrulation, the homologue of chordin. Thus, a comparable molecular mechanism for distinguishing non-neural ectoderm from neural ectoderm was probably present in the common ancestor of all bilaterally symmetrical animals.[well established][VHOG]" xsd:string {external_class="VHOG:0001372", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002346 name: neurectoderm def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] comment: Terminology notes: we prefer neurectoderm to neural ectoderm since placodal ectoderm is not classified here subset: uberon_slim subset: vertebrate_core synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] synonym: "presumptive central nervous system" RELATED [] xref: BILA:0000039 xref: EHDAA:1498 ! neural ectoderm xref: EHDAA:255 ! neural ectoderm xref: FBbt:00001061 ! ventral neurogenic region xref: FMA:87657 ! Neural ectoderm xref: VHOG:0000150 ! neuroectoderm xref: MAT:0000176 ! neurectoderm xref: MIAA:0000176 ! neurectoderm xref: TAO:0001120 ! neuroectoderm xref: XAO:0000042 ! neuroectoderm xref: ZFA:0001120 ! neuroectoderm xref: ncithesaurus:Neuroectoderm ! Neuroectoderm xref: EHDAA2:0001248 ! neural ectoderm xref: AAO:0011074 ! neuroectoderm xref: EMAPA:16073 ! neural ectoderm of ectoderm of embryo xref: EV:0100004 ! neuroectoderm is_a: UBERON:0000923 ! germ layer relationship: develops_from UBERON:0000924 {source="UBERONREF:0000002"} ! ectoderm relationship: has_part CL:0000133 ! neurectodermal cell relationship: has_part CL:0000530 {source="ZFA"} ! primary neuron synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] synonym: "ventral neurogenic region" RELATED [VHOG:0000150] property_value: homology_notes "(...) the ability of ectoderm to produce neuronal cells is a general metazoan feature.[well established][VHOG]" xsd:string {external_class="VHOG:0000150", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "neurectodermal" xsd:string xref: UMLS:C1518271 [Term] id: UBERON:0010232 name: placodal ectoderm is_a: UBERON:0000479 ! tissue relationship: develops_from UBERON:0000924 {source="UBERONREF:0000002"} ! ectoderm [Term] id: UBERON:0003075 name: neural plate def: "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]" [ISBN:0815318960, OMD:neural+plate, Wikipedia:Neural_plate, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "presumptive central nervous system" RELATED [] xref: EHDAA:346 ! neural plate xref: EHDAA:902 ! neural plate xref: VHOG:0000068 ! neural plate xref: TAO:0000132 ! neural plate xref: XAO:0000249 ! neural plate xref: ZFA:0000132 ! neural plate xref: ncithesaurus:Neural_Plate ! Neural Plate xref: BTO:0001765 ! neural plate xref: RETIRED_EHDAA2:0001252 ! neural plate xref: EMAPA:16095 ! neural plate of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16527 ! neural plate of future spinal cord of central nervous system of nervous system of organ system xref: EMAPA:16756 ! neural plate of future spinal cord of central nervous system of nervous system of tail of embryo is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0000483 {source="GO"} ! epithelium relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0002346 ! neural ectoderm relationship: part_of UBERON:0002346 {source="XAO"} ! neural ectoderm relationship: develops_from UBERON:0007284 {source="ZFA"} ! presumptive neural plate relationship: only_in_taxon NCBITaxon:7711 {source="GOTAX:0000352"} ! Chordata relationship: induced_by UBERON:0002328 {source="Wikipedia"} ! notochord xref: AAO:0011072 ! neural plate synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] xref: http://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png property_value: external_definition "The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000132", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000068", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0920623 [Term] id: UBERON:0005061 name: neural groove def: "The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds." [GOC:cjm, GO:0001842, Wikipedia:Neural_groove] xref: XAO:0000248 ! neural groove is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003075 ! neural plate xref: ncithesaurus:Neural_Groove ! Neural Groove xref: AAO:0011071 ! neural groove xref: SCTID:361463007 ! Neural groove property_value: external_definition "The neural groove is a shallow median groove between the neural folds of an embryo. The neural folds are two longitudinal ridges that are caused by a folding up of the ectoderm in front of the primitive streak of the developing embryo. The groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or canal, the ectodermal wall of which forms the rudiment of the nervous system. After the coalescence of the neural folds over the anterior end of the primitive streak, the blastopore no longer opens on the surface but into the closed canal of the neural tube, and thus a transitory communication, the neurenteric canal, is established between the neural tube and the primitive digestive tube. The coalescence of the neural folds occurs first in the region of the hind-brain, and from there extends forward and backward; toward the end of the third week the front opening (anterior neuropore) of the tube finally closes at the anterior end of the future brain, and forms a recess which is in contact, for a time, with the overlying ectoderm; the hinder part of the neural groove presents for a time a rhomboidal shape, and to this expanded portion the term sinus rhomboidalis has been applied. Before the neural groove is closed a ridge of ectodermal cells appears along the prominent margin of each neural fold; this is termed the neural crest or ganglion ridge, and from it the spinal and cranial nerve ganglia and the ganglia of the sympathetic nervous system are developed. By the upward growth of the mesoderm the neural tube is ultimately separated from the overlying ectoderm. The cephalic end of the neural groove exhibits several dilatations, which, when the tube is closed, assume the form of three vesicles; these constitute the three primary cerebral vesicles, and correspond respectively to the future fore-brain (prosencephalon), mid-brain (mesencephalon), and hind-brain (rhombencephalon). The walls of the vesicles are developed into the nervous tissue and neuroglia of the brain, and their cavities are modified to form its ventricles. The remainder of the tube forms the medulla spinalis or spinal cord; from its ectodermal wall the nervous and neuroglial elements of the medulla spinalis are developed while the cavity persists as the central canal[Wikipedia:Neural_groove]." xsd:string {source="Wikipedia:Neural_groove"} xref: UMLS:C0814992 [Term] id: UBERON:0005062 name: neural fold def: "One of the two elevated edges of the neural groove[GO,MP]." [GO:0001842, MP:0011256, Wikipedia:Neural_fold] synonym: "medullary fold" EXACT [MP:0011256] xref: EMAPA:16142 ! neural fold of future midbrain of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16146 ! neural fold of future prosencephalon xref: EMAPA:16151 ! neural fold of anterior pro-rhombomere xref: EMAPA:16155 ! neural fold of early hindbrain neural ectoderm xref: EMAPA:16159 ! neural fold of posterior pro-rhombomere xref: EMAPA:16288 ! neural fold of hindbrain posterior to rhombomere 05 xref: EMAPA:16292 ! neural fold of rhombomere 01 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16295 ! neural fold of rhombomere 02 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16299 ! neural fold of rhombomere 03 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16303 ! neural fold of rhombomere 04 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16307 ! neural fold of rhombomere 05 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16093 ! neural fold of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16162 ! neural fold of neural plate of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16528 ! neural fold of neural plate of future spinal cord of central nervous system of nervous system of organ system xref: EHDAA2:0001249 ! neural fold is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0005157 ! epithelial fold relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003075 ! neural plate xref: ncithesaurus:Neural_Fold ! Neural Fold xref: SCTID:361461009 ! Neural fold xref: XAO:0004087 ! neural fold property_value: external_definition "In front of the primitive streak two longitudinal ridges, caused by a folding up of the ectoderm, make their appearance, one on either side of the middle line. These are named the neural folds; they commence some little distance behind the anterior end of the embryonic disk, where they are continuous with each other, and from there gradually extend backward, one on either side of the anterior end of the primitive streak. Also, after differentiation it turns into the neural tubes[Wikipedia:Neural_fold]." xsd:string {source="Wikipedia:Neural_fold"} xref: UMLS:C0814993 [Term] id: UBERON:0003076 name: posterior neural tube comment: This class was created automatically from a combination of ontologies xref: VHOG:0001383 ! posterior neural tube xref: TAO:0007037 ! posterior neural tube xref: XAO:0000250 ! posterior neural tube xref: ZFA:0007037 ! posterior neural tube is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001049 ! neural tube relationship: develops_from UBERON:0003057 ! chordal neural plate xref: AAO:0011082 ! posterior neural tube property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001383", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0007135 ! neural keel name: neural keel def: "An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section." [ZFIN:ZDB-PUB-961014-576] synonym: "presumptive central nervous system" RELATED [ZFA:0000131] xref: TAO:0000131 ! neural keel xref: ZFA:0000131 ! neural keel xref: EFO:0003497 ! neural keel is_a: UBERON:0000479 ! portion of tissue relationship: develops_from UBERON:0003075 ! neural plate property_value: external_definition "An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000131", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005068 name: neural rod def: "a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]." [GO:0014024, ZFA:0000133] xref: ZFA:0000133 ! neural rod xref: EFO:0003498 ! neural rod is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0002346 ! neural ectoderm relationship: develops_from UBERON:0007135 ! neural keel xref: TAO:0000133 ! neural rod property_value: external_definition "An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000133", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0001049 name: neural tube def: "In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube] comment: The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium[GO:0021915] subset: uberon_slim subset: vertebrate_core synonym: "presumptive central nervous system" RELATED [] xref: BTO:0001057 xref: EHDAA:2869 ! neural tube xref: EHDAA:908 ! neural tube xref: EMAPA:16164 ! neural tube of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16530 ! neural tube of future spinal cord of central nervous system of nervous system of organ system xref: EMAPA:16757 ! neural tube of future spinal cord of central nervous system of nervous system of tail of embryo xref: VHOG:0000307 ! neural tube xref: MAT:0000069 ! neural tube xref: MIAA:0000069 ! neural tube xref: TAO:0001135 ! neural tube xref: ZFA:0001135 ! neural tube xref: XAO:0003204 ! neural tube xref: ncithesaurus:Neural_Tube ! Neural Tube xref: EHDAA2:0001254 ! neural tube xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001016 {source="GO"} ! nervous system relationship: develops_from UBERON:0002346 ! neural ectoderm relationship: develops_from UBERON:0005068 ! neural rod relationship: develops_into UBERON:0001017 ! central nervous system xref: AAO:0010617 ! neural tube xref: SCTID:362852000 ! Entire neural tube synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png property_value: external_definition "Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010617", date_retrieved="2012-06-20", source="AAO:JOR"} property_value: external_definition "The dorsal tubular structure in the vertebrate embryo that develops into the brain and spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000307", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/neural+tube", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000307", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231024 [Term] id: UBERON:0001054 name: Malpighian tubule def: "The most important structure of the insect's excretory organ, which may comprise cystiform or labyrinthine highly versatile tubules having their outlet into the inital section of the rectum[FBbt]. Any of a group of long blind vessels opening into the posterior part of the alimentary canal in most insects and some other arthropods and functioning primarily as excretory organs[BTO]." [ISBN:3110148986, Wikipedia:Malpighian_tubule] comment: Editor note: this will be ceded to the Arthropod Anatomy Ontology subset: uberon_slim synonym: "Malphigian tube" RELATED [BTO:0000810] synonym: "tuba Malpighii" RELATED [BTO:0000810] xref: BTO:0000810 xref: EFO:0000243 ! Malpighian tubule xref: FBbt:00005786 ! Malpighian tubule xref: FBbt:00001896 ! embryonic/larval Malpighian tubule xref: GAID:1228 ! malpighian tubule xref: MAT:0000123 ! Malpighian tubules xref: MIAA:0000123 ! Malpighian tubules xref: TADS:0000163 ! adult malpighian tubule xref: TGMA:0001038 ! adult Malpighian tubules xref: MESH:A13.574 ! malpighian tubule is_a: UBERON:0009773 {source="GO"} ! renal tubule relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda xref: SCTID:41055008 ! Malpighian tubules [Term] id: UBERON:0009962 name: excretory gland comment: todo - child terms def: "A gland that discharges its secretion through a duct opening on an internal or external surface of the body, as a lacrimal gland." [Dorlands_Medical_Dictionary:MerckSource] is_a: UBERON:0002530 {source="BTO"} ! gland relationship: part_of UBERON:0001008 ! excretory system xref: BTO:0000431 ! excretory gland [Term] id: UBERON:0009963 ! antennal gland name: antennal gland def: "Excretory gland situated in the basal article of the antennal peduncle. It functions to rehulate ionic balance" [BTO:0000075, UBERON:cjm] comment: Editor note: consider also classifying this as a renal tubule - or separate terms for coiled/nephridial canal. Editor note: cede this term to Arthropod AO synonym: "green gland" EXACT [] is_a: UBERON:0009962 {source="BTO"} ! excretory gland relationship: part_of UBERON:0000972 {source="BTO"} ! antenna relationship: only_in_taxon NCBITaxon:6657 ! Crustacea xref: BTO:0000075 ! antennal gland [Term] id: UBERON:0009964 name: crustacean maxillary gland def: "Excretory organ in maxillary segment with duct opening on maxilla." [http://crustacea.nhm.org/glossary/define.html] comment: Taxon notes: consider generalizing to include millipedes, centipedes. Function: Two different excretory organs are found among crustaceans: the antennal gland and the maxillary gland. Both have the same basic structure: an end sac and a convoluted duct that may expand into a bladder before opening to the outside. In most adult crustaceans only one or the other gland functions. The functional gland may change during the life cycle. Terminology note: http://crustacea.nhm.org/glossary/define.html?termID=327 suggests green gland as the generic term and antennal as the decapoda term. Editor note: cede this term to Arthropod AO is_a: UBERON:0009962 {source="BTO"} ! excretory gland relationship: only_in_taxon NCBITaxon:6657 ! Crustacea disjoint_from: UBERON:0001832 ! sublingual gland [Term] id: UBERON:0010264 ! hepatopancreas name: hepatopancreas def: "an organ of the digestive tract of arthropods and molluscs. It provides the functions which in mammals are provided separately by the liver and pancreas, including the production of digestive enzymes, and absorption of digested food." [Wikipedia:Hepatopancreas] is_a: UBERON:0006925 {source="BTO"} ! digestive gland relationship: part_of UBERON:0001045 {source="BTO"} ! midgut relationship: present_in_taxon NCBITaxon:6657 ! Crustacea xref: BTO:0000597 ! hepatopancreas disjoint_from: UBERON:0001264 ! pancreas disjoint_from: UBERON:0002107 ! liver [Term] id: UBERON:0010265 name: mollusc hepatopancreas def: "." [Wikipedia:Digestive_system_of_gastropods#Hepatopancreas] is_a: UBERON:0010264 ! hepatopancreas relationship: only_in_taxon NCBITaxon:6447 ! Mollusca [Term] id: UBERON:0010266 name: arthropod hepatopancreas def: "Digestive gland of crustaceans with functions approximately analogous to liver and pancreas of vertebrates - enzyme secretion, food absorption and storage." [BTO:0000597] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology synonym: "crustacean digestive gland" RELATED [] synonym: "midgut gland" RELATED [BTO:0000597] is_a: UBERON:0010264 ! hepatopancreas relationship: part_of UBERON:0002405 {source="PMID:18025161"} ! immune system relationship: has_part CL:0000387 {source="PMID:18025161"} ! hemocyte (sensu Nematoda and Protostomia) relationship: only_in_taxon NCBITaxon:6657 ! Crustacea [Term] id: UBERON:0009965 name: coxal gland def: "a gland found in some arthropods, for collecting and excreting urine. The gland comprises an end sac (saccule), a long duct (labyrinth) and a terminal bladder (reservoir). There is generally only one pair (two in some spiders), and they open on the coxae of the walking legs[WP]." [Wikipedia:Coxal_gland] comment: Taxon notes: They are found in all arachnids (with the exception of some Acari), and in other chelicerates, such as horseshoe crabs. Homology: The coxal gland is thought to be homologous with the antennal gland of crustaceans. Editor note: cede this term to Arthropod AO is_a: UBERON:0009962 {source="BTO"} ! excretory gland relationship: homologous_to UBERON:0009963 ! antennal gland relationship: only_in_taxon NCBITaxon:6854 ! Arachnida xref: TADS:0000080 ! adult coxal gland xref: SPD:0000116 ! coxal gland [Term] id: UBERON:0001055 name: obsolete ureter def: "the tube that conducts the urine from the renal pelvis to the bladder." [MP:0000534] is_obsolete: true consider: UBERON:0000056 consider: UBERON:0000057 [Term] id: UBERON:0001053 name: neurohemal organ def: "A system of neurons that has the specialized function to produce and secrete hormones, and that constitutes, in whole or in part, an endocrine organ or system." [BTO:0002106] relationship: part_of UBERON:0001016 {source="BTO"} ! nervous system synonym: "neurohaemal organ" RELATED [] xref: EFO:0000864 ! neurohemal organ xref: FBbt:00005757 ! neurohemal organ xref: MAT:0000212 ! neurohemal organ xref: MIAA:0000212 ! neurohemal organ xref: BTO:0002106 ! neurohemal organ is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001016 ! nervous system subset: organ_slim [Term] id: UBERON:0012325 name: retrocerebral complex def: "Corpora allata with Corpora cardiaca form the retrocerebral complex, a neurosecretory organ." [BTO:0001803] is_a: UBERON:0002368 {source="BTO"} ! endocrine gland xref: BTO:0001803 ! retrocerebral complex xref: FBbt:00001718 ! retrocerebral complex [Term] id: UBERON:0001056 name: corpus cardiacum def: "One of a pair of neurohemal organs located on the walls of the aorta just behind the brain. The corpora cardiaca release their store of PTTH only after they receive a signal from neurosecretory cells in the brain." [BTO:0000432, http://en.wikipedia.org/wiki/Corpus_cardiacum#Endocrine_system] comment: will be ceded to arthropod anatomy ontology synonym: "corpora cardiaca" RELATED PLURAL [BTO:0000432] xref: BTO:0000432 xref: EFO:0000380 ! corpus cardiacum xref: FBbt:00005799 ! corpus cardiacum xref: MAT:0000211 ! corpus cardiacum xref: MIAA:0000211 ! corpus cardiacum is_a: UBERON:0002368 {source="BTO"} ! endocrine gland relationship: part_of UBERON:0012325 {source="BTO-modified"} ! retrocerebral complex [Term] id: UBERON:0001057 name: corpus allatum def: "One of a pair of separate or fused bodies in many insects that are sometimes closely associated with the corpora cardiaca and that secrete hormones (as juvenile hormone)[BTO]." [BTO:0000291, http://en.wikipedia.org/wiki/Corpora_allata] comment: will be ceded to arthropod anatomy ontology subset: uberon_slim synonym: "corpora allata" RELATED PLURAL [BTO:0000291] xref: BTO:0000291 xref: EFO:0000379 ! corpus allatum xref: FBbt:00005800 ! corpus allatum xref: MAT:0000210 ! corpus allatum xref: MIAA:0000210 ! corpus allatum xref: MESH:A08.713.100 ! corpora allata is_a: UBERON:0002368 {source="BTO"} ! endocrine gland relationship: part_of UBERON:0012325 {source="BTO-modified"} ! retrocerebral complex relationship: capable_of GO:0045443 {source="Wikipedia"} ! juvenile hormone secretion [Term] id: UBERON:0001058 name: mushroom body def: "Prominent lobed neuropils found in annelids and all arthropods except crustaceans. They are thought to be involved in olfactory associative learning and memory[MESH] Mushroom body neuropils are divided into calyces, pedunculus, and its subsequent lobes. In Drosophila these are the alpha, beta, and gamma lobes." [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html, Wikipedia:Mushroom_body, MESH:A13.641] comment: Taxon notes: Also in annelids. "Comparison to the verte- brate pallium reveals that the annelid mushroom bodies develop from similar molecular coordinates within a conserved overall molecular brain topology and that their development involves conserved patterning mechanisms and produces conserved neuron types that existed already in the proto- stome-deuterostome ancestors. These data indicate deep homology of pallium and mushroom bodies and date back the origin of higher brain centers to prebilaterian times" [PMID:20813265] subset: uberon_slim synonym: "corpora pedunculata" EXACT [FBbt:00005801] synonym: "mushroom bodies" EXACT PLURAL [] xref: EFO:0000925 ! mushroom body xref: FBbt:00005801 ! mushroom body xref: GAID:1231 ! mushroom body xref: MAT:0000336 ! mushroom body xref: MIAA:0000336 ! mushroom body xref: BTO:0002675 ! mushroom body xref: MESH:A13.641 ! mushroom body is_a: UBERON:0000045 ! ganglion relationship: part_of UBERON:0000955 ! brain relationship: only_in_taxon NCBITaxon:33317 {notes="annelids and arthropods"} ! Protostomia relationship: present_in_taxon NCBITaxon:6340 ! Annelida relationship: present_in_taxon NCBITaxon:6656 ! Arthropoda relationship: never_in_taxon NCBITaxon:6217 ! Nemertea relationship: has_function_in GO:0008355 {source="Wikipedia"} ! olfactory learning relationship: has_function_in GO:0007613 {source="Wikipedia"} ! memory [Term] id: UBERON:0001059 name: pars intercerebralis def: "a neurosecretory center of the insect brain, located along the anterior midline[wiktionary]. A medial cleft or depression dividing the left and right protocerebrum and containing numerous large and small somata of neurosecretory and neuromodulatory neurons[FBbt]." [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html, http://en.wiktionary.org/wiki/pars_intercerebralis] comment: will be ceded to arthropod anatomy ontology subset: uberon_slim xref: EFO:0000926 ! pars intercerebralis xref: FBbt:00005802 ! pars intercerebralis xref: MAT:0000337 ! pars intercerebralis xref: MIAA:0000337 ! pars intercerebralis is_a: UBERON:0005162 ! multi cell component structure relationship: part_of UBERON:0000955 {source="FBbt"} ! brain relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0001062 name: anatomical entity def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [CARO:MAH, FMA:62955] subset: upper_level xref: BILA:0000000 xref: FBbt_root:00000000 ! anatomical entity xref: FBbt:10000000 ! anatomical entity xref: FMA:62955 ! Anatomical entity xref: HAO:0000000 ! anatomical entity xref: NIF_GrossAnatomy:birnlex_6 xref: TAO:0100000 ! teleost anatomical entity xref: ZFA:0100000 ! zebrafish anatomical entity xref: NIF_GrossAnatomy:birnlex_6 ! Anatomical entity xref: EHDAA2:0002229 ! anatomical entity xref: AEO:0000000 ! anatomical entity xref: CARO:0000000 ! anatomical entity xref: TGMA:0001822 ! anatomical entity xref: MA:0000001 ! mouse anatomical entity xref: AAO:0010841 ! unclassified anatomical entity xref: ncithesaurus:Anatomic_Structure_System_or_Substance ! anatomic structure, system, or substance xref: UMLS:C1515976 [Term] id: UBERON:0001063 name: flocculus alt_id: UBERON:Flocculus-MA_0000992 def: "a small lobe of the cerebellum at the posterior border of the middle cerebellar peduncle anterior to the biventer lobule[WP]." [Wikipedia:Flocculus_(cerebellar)] comment: AO Notes: flocculus is an exact label for two distinct classes in NIF. Function notes: At its base, the flocculus receives input from the middle ears vestibular system and regulates balance. Many floccular projections descend to the spinal cord and connect to the motor nuclei involved in control of eye movement.[WP]. Taxon notes: enlarged in pterosaurs[PMID:14586467] subset: uberon_slim synonym: "hemispheric lobule X" RELATED INCONSISTENT [NIF_GrossAnatomy:nlx_anat_20081213] xref: MA:0000992 ! flocculus xref: FMA:83881 ! Flocculus of cerebellum xref: NIF_GrossAnatomy:birnlex_1329 ! Flocculus xref: ABA:FL ! Flocculus is_a: UBERON:0002749 ! regional part of cerebellar cortex relationship: part_of UBERON:0002245 ! hemisphere of cerebellum relationship: part_of UBERON:0003012 {source="FMA-abduced-lr"} ! flocculonodular lobe relationship: spatially_disjoint_from UBERON:0005348 {source="ABA"} ! ansiform lobule relationship: spatially_disjoint_from UBERON:0005347 {source="ABA"} ! copula pyramidis relationship: spatially_disjoint_from UBERON:0005351 {source="ABA"} ! paraflocculus relationship: spatially_disjoint_from UBERON:0005349 {source="ABA"} ! paramedian lobule relationship: spatially_disjoint_from UBERON:0005350 {source="ABA"} ! lobule simplex xref: SCTID:30711003 ! Flocculus synonym: "flocculus of cerebellum" EXACT [FMA:83881] synonym: "H X" RELATED [FMA:83881] synonym: "lobule X" RELATED [FMA:83881] synonym: "neuraxis flocculus" EXACT [FMA:83881] [Term] id: UBERON:0004913 ! hepatopancreatic ampulla name: hepatopancreatic ampulla def: "A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct." [Wikipedia:Ampulla_of_Vater] subset: vertebrate_core synonym: "ampulla of Vater" EXACT [] synonym: "Vater's ampulla" EXACT [] synonym: "biliaropancreatic ampulla" EXACT [] synonym: "ampulla of bile duct" EXACT [FMA:15076] synonym: "papilla duodeni major" RELATED [ZFA:0005167] synonym: "papilla Vateri" EXACT [ZFA:0005167] xref: GAID:283 ! vater's ampulla xref: FMA:15076 ! hepatopancreatic ampulla xref: ZFA:0005167 ! hepatopancreatic ampulla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Biliary_system_new.svg/200px-Biliary_system_new.svg.png xref: MESH:A03.159.183.079.300.900 ! vater's ampulla intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0004914 ! duodenal papilla intersection_of: part_of UBERON:0001174 ! common bile duct synonym: "ampulla biliaropancreatica" EXACT LATIN [FMA:TA, FMA:15076] xref: ncithesaurus:Ampulla_of_Vater ! Ampulla of Vater xref: galen:AmpullaOfVater xref: SCTID:362200007 ! Entire ampulla of Vater xref: TAO:0005167 ! hepatopancreatic ampulla synonym: "Ampulla hepatopancreatica, ampulla Vaterii" RELATED LATIN [Wikipedia:Ampulla_of_Vater] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Biliary_system_new.svg property_value: external_definition "Ampulla formed by the union of the pancreatic duct and the common bile duct where they enter the intestine.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005167", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-070212-11", source="ZFIN:ZDB-PUB-080414-12"} xref: UMLS:C0042425 [Term] id: UBERON:0004914 name: duodenal papilla synonym: "papilla of duodenum" EXACT [] synonym: "papilla duodenalis" EXACT [] xref: FMA:15953 ! duodenal papilla xref: EMAPA:18662 ! duodenal papilla of duodenum of foregut-midgut junction xref: EMAPA:18853 ! duodenal papilla of duodenum of gut xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/43/Gray1057.png/200px-Gray1057.png is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002114 ! duodenum xref: SCTID:245389007 ! Entire duodenal papilla synonym: "papilla duodeni major" RELATED LATIN [Wikipedia:Major_duodenal_papilla] synonym: "papilla duodeni minor" RELATED LATIN [Wikipedia:Minor_duodenal_papilla] xref: http://upload.wikimedia.org/wikipedia/commons/4/43/Gray1057.png [Term] id: UBERON:0012271 name: major duodenal papilla def: "The common bile duct and the pancreatic duct together perforate the medial side of the second portion of the duodenum obliquely, some 7 to 10 cm below the pylorus, forming a structure called the major duodenal papilla. The accessory pancreatic duct sometimes pierces it about 2 cm above and slightly in front of these." [Wikipedia:Major_duodenal_papilla] synonym: "major papilla" RELATED [Wikipedia:Major_duodenal_papilla] synonym: "papilla duodeni major" RELATED LATIN [Wikipedia:Major_duodenal_papilla] synonym: "greater duodenal papilla" EXACT [FMA:15074] synonym: "tubercle of Vater" EXACT [FMA:15074] is_a: UBERON:0004914 ! duodenal papilla xref: FMA:15074 ! major duodenal papilla xref: SCTID:181272007 ! Entire greater duodenal papilla [Term] id: UBERON:0012272 name: minor duodenal papilla def: "The minor duodenal papilla is the opening of the accessory pancreatic duct into the duodenum. It is sometimes absent, and often nonfunctional." [Wikipedia:Minor_duodenal_papilla] synonym: "minor papilla" RELATED [Wikipedia:Minor_duodenal_papilla] synonym: "Santorini's minor caruncle" EXACT [Wikipedia:Minor_duodenal_papilla] synonym: "lesser duodenal papilla" EXACT [FMA:15075] synonym: "Santorini's caruncle" EXACT [FMA:15075] is_a: UBERON:0004914 ! duodenal papilla xref: FMA:15075 ! minor duodenal papilla xref: SCTID:245390003 ! Entire lesser duodenal papilla [Term] id: UBERON:0012273 ! periampullary region of duodenum name: periampullary region of duodenum synonym: "periampullary region" EXACT [] is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0002114 ! duodenum xref: ncithesaurus:Periampullary_Region ! periampullary region xref: UMLS:C1882332 [Term] id: UBERON:0013644 name: duodenal ampulla def: "the very first part of the duodenum which is slightly dilated." [Wikipedia:Duodenal_cap] synonym: "ampulla (duodenum)" EXACT [FMA:14927] synonym: "ampulla duodeni" EXACT [FMA:TA] synonym: "ampulla of duodenum" EXACT [FMA:14927] synonym: "bulbus (duodenum)" EXACT [FMA:14927] synonym: "bulbus duodeni" EXACT [FMA:TA] synonym: "duodenal cap" EXACT [FMA:14927] synonym: "duodenal cap viewed radiologically" EXACT [FMA:14927] is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0002114 ! duodenum relationship: adjacent_to UBERON:0000945 ! stomach xref: FMA:14927 ! duodenal ampulla xref: SCTID:362149005 ! Entire duodenal ampulla [Term] id: UBERON:0005050 name: liver papillary process synonym: "processus papillaris" EXACT [FMA:14506] synonym: "papillary process of caudate lobe of liver" EXACT [FMA:14506] xref: FMA:14506 ! Papillary process of caudate lobe of liver xref: MA:0001643 ! liver papillary process is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0002107 ! liver xref: SCTID:271187002 ! Entire papillary process of caudate lobe of liver [Term] id: UBERON:0004915 name: sphincter of hepatopancreatic ampulla def: "muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. Relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[WP]." [Wikipedia:Sphincter_of_ampulla] synonym: "sphincter of Oddi" EXACT [] synonym: "Oddi's sphincter" EXACT [] synonym: "hepatopancreatic ampullary sphincter" EXACT [FMA:15077] synonym: "musculus sphincter ampullae" EXACT [FMA:15077] synonym: "sphincter of ampulla of vater" EXACT [FMA:15077] xref: GAID:285 ! oddi's sphincter xref: FMA:15077 ! sphincter of hepatopancreatic ampulla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/43/Gray1057.png/200px-Gray1057.png xref: EMAPA:18663 ! sphincter of Oddi of duodenum of foregut-midgut junction xref: EMAPA:18854 ! sphincter of Oddi of duodenum of gut xref: MESH:A03.159.183.079.300.900.600 ! oddi's sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0004913 ! hepatopancreatic ampulla xref: ncithesaurus:Sphincter_of_Oddi ! Sphincter of Oddi xref: SCTID:181271000 ! Entire sphincter of Oddi xref: http://upload.wikimedia.org/wikipedia/commons/4/43/Gray1057.png xref: UMLS:C0028872 [Term] id: UBERON:0001065 name: parotid duct def: "The parotid duct, also known as Stensen's duct, is the route that saliva takes from the parotid gland into the mouth. It passes through the buccal fat, buccopharyngeal fascia, and buccinator muscle then opens into the vestibule of the mouth opposite the upper second molar tooth. The buccinator acts as a valve that prevents inflation of the duct during blowing. Running along with the duct superiorly is the transverse facial artery and upper buccal nerve; running along with the duct inferiorly is the lower buccal nerve. [WP,unvetted]." [Wikipedia:Parotid_duct] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "duct of parotid gland" EXACT [] synonym: "stenon duct" EXACT [] synonym: "Stensen's duct" EXACT [] synonym: "Stensens's duct" EXACT [] synonym: "duct of parotid" EXACT [OBOL:automatic] synonym: "parotid gland duct" EXACT [OBOL:automatic] xref: FMA:10420 ! Parotid duct xref: MA:0002697 ! parotid duct xref: ncithesaurus:Parotid_Duct ! Parotid Duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a1/Gray1023.png/200px-Gray1023.png xref: BTO:0004554 ! parotid gland duct is_a: UBERON:0001837 ! duct of salivary gland intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001831 ! parotid gland relationship: part_of UBERON:0001831 ! parotid gland relationship: channels_from UBERON:0001831 ! parotid gland xref: SCTID:362175009 ! Entire parotid duct synonym: "ductus parotideus" RELATED LATIN [Wikipedia:Parotid_duct] xref: http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray1023.png xref: UMLS:C0227458 [Term] id: UBERON:0001068 name: skin of back def: "A zone of skin that is part of a back [Automatically generated definition]." [OBOL:automatic] comment: todo - distinguish between entire skin of region and arbitrary zone of skin on region synonym: "skin, dorsal region" EXACT [UBERON:cjm] synonym: "back skin" EXACT [] synonym: "back zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of back" EXACT [OBOL:automatic] xref: FMA:10462 ! Skin of back xref: MA:0000498 ! back skin xref: FMA:22985 ! Zone of skin of back is_a: UBERON:0001085 {source="MA"} ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0011270 {source="MA"} ! dorsal trunk xref: SCTID:181492002 ! Entire skin of back [Term] id: UBERON:0005191 name: obsolete cervical artery def: "An artery that is part of a uterine cervix [Automatically generated definition]." [OBOL:automatic] is_obsolete: true [Term] id: UBERON:0012320 name: cervical artery def: "An artery of the neck" [UBERON:cjm] xref: ncithesaurus:Cervical_Artery ! Cervical Artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0000974 ! neck xref: UMLS:C1707349 [Term] id: UBERON:0012324 name: transverse cervical artery def: "The transverse cervical artery (transverse artery of neck, transversa colli artery) is a branch of the thyrocervical trunk, running at a higher level than the suprascapular artery." [Wikipedia:Transverse_cervical_artery] comment: AO notes: Unclear if MA class belongs here or in parent synonym: "cervical artery" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "cervical transverse artery" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "descending branch of the transverse cervical" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transversalis artery colli" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transversalis colli artery" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transverse cervical" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transverse cervical vessels" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "cervical artery" RELATED [MA:0001936] xref: FMA:10664 ! transverse cervical artery xref: MA:0001936 ! cervical artery xref: SCTID:244224008 ! Entire transverse cervical artery is_a: UBERON:0001637 {source="MA"} ! artery relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0001071 name: superficial cervical artery def: "It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery. ." [Wikipedia:Superficial_branch_of_transverse_cervical_artery] comment: The transverse cervical artery splits into two branches, a superficial one and a deep one[WP] synonym: "superficial branch of transverse cervical artery" EXACT [Wikipedia:Superficial_branch_of_transverse_cervical_artery] subset: uberon_slim xref: FMA:10665 ! Superficial cervical artery xref: MA:0002052 ! superficial cervical artery xref: ncithesaurus:Superficial_Cervical_Artery ! Superficial Cervical Artery is_a: UBERON:0001637 ! artery relationship: part_of UBERON:0000974 ! neck xref: SCTID:161746006 ! Entire superficial cervical artery xref: Wikipedia:Superficial_branch_of_transverse_cervical_artery ! superficial branch of transverse cervical artery xref: UMLS:C0226271 [Term] id: UBERON:0012321 name: deep cervical artery def: "The deep cervical artery (Profunda cervicalis) is an artery of the neck." [Wikipedia:Deep_cervical_artery] synonym: "profunda cervicalis" RELATED [Wikipedia:Deep_cervical_artery] is_a: UBERON:0001637 ! artery relationship: part_of UBERON:0000974 ! neck relationship: branch_of UBERON:0004688 {source="FMA"} ! costo-cervical trunk xref: FMA:10659 ! deep cervical artery xref: SCTID:244223002 ! Entire deep cervical artery [Term] id: UBERON:0012322 name: ascending cervical artery def: "The ascending cervical artery is a small branch which arises from the inferior thyroid artery as that vessel is passing behind the carotid sheath; it runs up on the anterior tubercles of the transverse processes of the cervical vertebrC& in the interval between the Scalenus anterior and Longus capitis. To the muscles of the neck it gives twigs which anastomose with branches of the vertebral, and it sends one or two spinal branches into the vertebral canal through the intervertebral foramina to be distributed to the medulla spinalis and its membranes, and to the bodies of the vertebrC&, in the same manner as the spinal branches from the vertebral. It anastomoses with the ascending pharyngeal and occipital arteries." [Wikipedia:Ascending_cervical_artery] synonym: "ascending cervical" RELATED [Wikipedia:Ascending_cervical_artery] is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0007149 {source="FMA"} ! inferior thyroid artery relationship: part_of UBERON:0007149 {source="FMA"} ! inferior thyroid artery relationship: part_of UBERON:0000974 ! neck xref: FMA:52489 ! ascending cervical artery xref: SCTID:161846001 ! Entire ascending cervical artery [Term] id: UBERON:0004087 name: vena cava def: "The superior and inferior vena cava are collectively called the venae cavae. They are the veins that return deoxygenated blood from the body into the heart. They both empty into the right atrium. The inferior vena cava (or posterior vena cava in animals) travels up alongside the abdominal aorta with blood from the lower part of the body (see # 11 in the diagram). It is the largest vein in the body. The superior vena cava (or anterior vena cava in animals) is above the heart, and forms from a convergence of the left and right brachiocephalic veins that contain blood from the head and the arms (see # 3 in the diagram). [WP,unvetted]." [Wikipedia:Venae_cavae] xref: MA:0000068 ! vena cava xref: EMAPA:18415 ! vena cava xref: GAID:547 ! venae cavae xref: BTO:0001438 ! vena cava xref: OpenCyc:Mx4rkJQ4U6gEEdudWQACs5b6Bw ! vena cava xref: ncithesaurus:Vena_Cava ! Vena Cava xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7c/Heart_numlabels.png/200px-Heart_numlabels.png xref: MESH:A07.231.908.949 ! venae cavae is_a: UBERON:0001638 ! vein relationship: located_in UBERON:0002224 ! thoracic cavity xref: AAO:0010215 ! vena cava xref: SCTID:244405007 ! Entire vena cava xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Relations_of_the_aorta,_trachea,_esophagus_and_other_heart_structures.png xref: UMLS:C0042460 [Term] id: UBERON:0001072 ! inferior vena cava name: inferior vena cava def: "Trunk of systemic vein which is formed by the union of the right common iliac vein and the left common iliac vein and terminates in the right atrium." [Wikipedia:Inferior_vena_cava] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "posterior vena cava" EXACT [] synonym: "vena cava inferior" RELATED [BTO:0002682] xref: FMA:10951 ! Inferior vena cava xref: GAID:548 ! inferior vena cava xref: galen:InferiorVenaCava xref: VHOG:0001194 ! posterior vena cava xref: MA:0000480 ! inferior vena cava xref: XAO:0000388 ! posterior vena cava xref: ncithesaurus:Inferior_Vena_Cava ! Inferior Vena Cava xref: BTO:0002682 ! inferior vena cava xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray577.png/200px-Gray577.png xref: EMAPA:18416 ! inferior of vena cava xref: MESH:A07.231.908.949.648 ! inferior vena cava is_a: UBERON:0004087 ! vena cava relationship: develops_from UBERON:0005487 {source="Wikipedia:Vitelline_vein"} ! vitelline vein xref: AAO:0011083 ! posterior vena cava xref: SCTID:181369003 ! Entire inferior vena cava xref: EHDAA2:0000611 ! inferior vena cava synonym: "vena cava inferior" RELATED LATIN [Wikipedia:Inferior_vena_cava] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray577.png synonym: "caudal vena cava" RELATED [VHOG:0001194] property_value: homology_notes "Phylogenetic modifications within this basic pattern of arteries and veins are largely correlated with functional changes. In the transition from water to land, gills gave way to lungs, accompanied by the establishment of a pulmonary circulation. In some fishes and certainly in tetrapods, the cardinal veins become less involved in blood return. Instead, the composite, prominent postcava (posterior vena cava) arose to drain the posterior part of the body and the precava (anterior vena cava) developed to drain the anterior part of the body.[well established][VHOG]" xsd:string {external_class="VHOG:0001194", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.454-455", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0042458 [Term] id: UBERON:0001073 name: ileocecal junction def: "A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice" [http://www.medilexicon.com/medicaldictionary.php?t=46539] comment: This class was created automatically from a combination of ontologies synonym: "ileocaecal junction" EXACT [] xref: FMA:11338 ! Ileocecal junction xref: MA:0000332 ! ileocaecal junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000059 ! large intestine intersection_of: connects UBERON:0002108 ! small intestine relationship: part_of UBERON:0000160 ! intestine xref: SCTID:264021000 ! Ileocecal junction [Term] id: UBERON:0001074 name: pericardial cavity def: "Cavity of serous sac surrounded by serous pericardium.[FMA]" [Wikipedia:Pericardial_cavity, FMA:FMA] subset: uberon_slim subset: vertebrate_core synonym: "pericardial space" EXACT [Wikipedia:Pericardial_cavity] synonym: "cavity of pericardial sac" EXACT [] xref: FMA:11350 ! Pericardial cavity xref: VHOG:0000556 ! pericardial cavity xref: MA:0000053 ! pericardial cavity xref: ZFA:0001655 ! pericardial cavity xref: ncithesaurus:Pericardial_Cavity ! Pericardial Cavity xref: EHDAA2:0001434 ! pericardial cavity xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray968.png/200px-Gray968.png xref: EMAPA:18447 ! pericardial cavity xref: EMAPA:18448 ! cavity of pericardial cavity intersection_of: UBERON:0002323 ! coelemic cavity lumen intersection_of: part_of UBERON:0002406 ! pericardial sac intersection_of: surrounded_by UBERON:0002357 ! serous pericardium is_a: UBERON:0002323 {source="MA"} ! body cavity relationship: part_of UBERON:0002406 {source="FMA"} ! pericardial sac relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom relationship: present_in_taxon NCBITaxon:7718 {source="PMID:20959416"} ! Ciona xref: SCTID:362027001 ! Entire pericardial cavity xref: TAO:0002220 ! pericardial cavity synonym: "cavitas pericardiaca" RELATED LATIN [Wikipedia:Pericardial_cavity] xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray968.png property_value: external_definition "Anatomical space in which the heart is located and is surrounded by the pericardium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002220", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: galen:PericardialSpace ! pericardial space property_value: homology_notes "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart (of other tetrapods) is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {external_class="VHOG:0000556", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0225972 [Term] id: UBERON:0001130 name: vertebral column def: "Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body." [Wikipedia:Vertebral_column, UBERON:cjm, https://sourceforge.net/tracker/?func=detail&aid=3530322&group_id=76834&atid=2257941] comment: Editor notes: Note that in contrast to VSAO, this is a subset of the skeletal system, and thus includes intervertebral joints, cartilage and ligaments etc. Some ontologies such as AAO seem to purely refer to the skeleton subset: uberon_slim subset: vertebrate_core synonym: "backbone" NARROW [FMA:13478] synonym: "spine" BROAD [FMA:13478] synonym: "spinal column" RELATED [MESH:A02.835.232.834] synonym: "vertebral column skeleton" NARROW [AAO:0000699] synonym: "columna vertebralis" RELATED [BTO:0000818] synonym: "vertebral region" RELATED [] xref: AAO:0000734 ! vertebral_column xref: BTO:0000818 xref: EHDA:10119 ! spinal xref: EMAPA:16666 ! spinal xref: FMA:13478 ! Vertebral column xref: GAID:106 ! spine xref: VHOG:0001142 ! vertebral column xref: MA:0002416 ! vertebral column xref: OpenCyc:Mx4rv6GF55wpEbGdrcN5Y29ycA xref: TAO:0001559 ! vertebral column xref: XAO:0003074 ! vertebral column xref: ZFA:0001559 ! vertebral column xref: ncithesaurus:Spinal_Cord_Column ! Spinal Cord Column xref: ncithesaurus:Vertebral_Column ! Vertebral Column xref: EFO:0001369 ! vertebral column structure xref: galen:SpinalColumn ! spinal column xref: OpenCyc:Mx4rv2j-CpwpEbGdrcN5Y29ycA ! backbone xref: OpenCyc:Mx4rv6GF55wpEbGdrcN5Y29ycA ! vertebral column xref: OpenCyc:Mx4rvVkFEpwpEbGdrcN5Y29ycA ! spinal column xref: NIF_Subcellular:sao1145756102 ! Spine xref: AAO:0000699 ! vertebral column skeleton xref: MESH:A02.835.232.834 ! spine is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: part_of UBERON:0011138 {source="cjm"} ! post-cranial axial skeletal system xref: SCTID:44300000 ! Entire vertebral column xref: VSAO:0000185 ! vertebral column property_value: external_definition "Anatomical cluster that consists of all the vertebra in the body.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000185", date_retrieved="2012-08-14", source="VSAO:curator"} property_value: external_definition "The vertebral column consists of a series of vertebrae connected by ligaments. It provides a supporting axis for the body and protects the spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001142", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/vertebral+column", source="http://bgee.unil.ch/"} property_value: homology_notes "Vertebrata is characterized by three synapomorphies. First, vertebrates have a backbone composed of vertebrae (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001142", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.53", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1519455 xref: UMLS:C0037949 [Term] id: UBERON:0010913 ! vertebral element name: vertebral element def: "Skeletal element that forms around the notochord and is part of the vertebral column." [VSAO:0000184] comment: Note that Uberon includes a distinct subclass for bony vertebra is_a: UBERON:0004765 {source="VSAO"} ! skeletal element relationship: part_of UBERON:0001130 {source="VSAO"} ! vertebral column relationship: develops_from UBERON:0003089 {source="cjm"} ! sclerotome xref: VSAO:0000184 ! vertebral element xref: VHOG:0001143 ! vertebra (also: UBERON:0002412 'vertebra') property_value: homology_notes "In contrast to lampreys and jawed vertebrates, hagfishes were thought to lack vertebrae. Now, long overlooked vertebral rudiments have been analysed in hagfish, suggesting that vertebrae existed in the last common ancestor of all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0001143", ontology="VHOG", source="DOI:10.1016/j.cub.2011.07.014 Janvier P\, Comparative anatomy: all vertebrates do have vertebrae. Current Biology (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "vertebral" xsd:string [Term] id: UBERON:0002412 ! vertebra name: vertebra def: "Irregular bone that articulates with other vertebrae, or with one other vertebra and the skull or the sacrum[FMA]. All serially repeated ossified, cartilaginous, and ligamentous elements around the notochord (Schultze and Arratia, 1988)[ZFA]." [Wikipedia:Vertebra, ZFIN:curator, FMA:9914] comment: Editor notes: Consider changing name to make distinction from inferred superclass 'vertebral element' clear // note we follow FMA in making this an irregular bone - however vertebra have epiphyses which are currently classified as belonging to long bones subset: uberon_slim subset: vertebrate_core synonym: "vertebra bone" EXACT [] synonym: "vertebrae" EXACT PLURAL [PHENOSCAPE:ad] xref: AAO:0000691 ! vertebra xref: FMA:9914 ! Vertebra xref: VHOG:0001143 ! vertebra (also: UBERON:0010913 'vertebral element') xref: MA:0000309 ! vertebra xref: TAO:0001189 ! vertebra xref: ZFA:0001189 ! vertebra xref: ncithesaurus:Vertebra ! Vertebra xref: EFO:0001371 ! vertebra xref: galen:Vertebra ! vertebra xref: OpenCyc:Mx4rvt2Dh5wpEbGdrcN5Y29ycA ! vertebra is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0010913 ! vertebral element relationship: part_of UBERON:0001130 ! vertebral column relationship: develops_from UBERON:0011094 ! vertebra cartilaginous condensation xref: SCTID:181817002 ! Entire vertebra xref: XAO:0004019 ! vertebra property_value: external_definition "Main component of the vertebral column. It consists of two essential parts, a dorsal neural arch and a ventral centrum.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000691", date_retrieved="2012-06-20", source="AAO:Pugener_and_Maglia_2008"} property_value: external_definition "Endochondral bone that forms around the notochord and is part of the vertebral column.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001189", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "In contrast to lampreys and jawed vertebrates, hagfishes were thought to lack vertebrae. Now, long overlooked vertebral rudiments have been analysed in hagfish, suggesting that vertebrae existed in the last common ancestor of all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0001143", ontology="VHOG", source="DOI:10.1016/j.cub.2011.07.014 Janvier P\, Comparative anatomy: all vertebrates do have vertebrae. Current Biology (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0549207 xref: CALOHA:TS-2352 ! Vertebra [Term] id: UBERON:0011094 name: vertebra cartilaginous condensation comment: AO notes: This class is a superclass of individual vertebral cartilage condensations. Note that EHDAA2 represents these as condensation groups is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0001130 ! vertebral column relationship: develops_into UBERON:0002412 ! vertebra ! vertebra relationship: develops_from UBERON:0011095 ! vertebra pre-cartilage condensation xref: VHOG:0000584 ! vertebral cartilage condensation synonym: "vertebral cartilage condensation" EXACT [VHOG:0000584] def: "A cartilaginous condensation that is part of a vertebral column." [OBOL:automatic] [Term] id: UBERON:0011095 name: vertebra pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0001130 ! vertebral column relationship: develops_into UBERON:0002412 ! vertebra ! vertebra relationship: develops_from UBERON:0003089 {source="EHDAA2-abduced"} ! sclerotome xref: VHOG:0000582 ! vertebral pre-cartilage condensation synonym: "vertebral pre-cartilage condensation" EXACT [VHOG:0000582] def: "A pre-cartilage condensation that is part of a vertebral column." [OBOL:automatic] [Term] id: UBERON:0001075 ! body of vertebra name: body of vertebra def: "The body is the largest part of a vertebra, and is more or less cylindrical in shape. Its upper and lower surfaces are flattened and rough, and give attachment to the intervertebral fibrocartilages, and each presents a rim around its circumference. In front, the body is convex from side to side and concave from above downward. Behind, it is flat from above downward and slightly concave from side to side. Its anterior surface presents a few small apertures, for the passage of nutrient vessels. On the posterior surface is a single large, irregular aperture, or occasionally more than one, for the exit of the basi-vertebral veins from the body of the vertebra. [WP,unvetted]." [Wikipedia:Body_of_vertebra] comment: AO notes: VSAO definition states it surrounds notochord but not applicable to post-natal. Editor notes: vertebra classes required generalization for cartilage columns // todo - add subclasses: acoelus, amphicoelus, procoelus, opsithocoelus, heterocoelus; pleurocentrum, intercentrum; todo: add developmental relationships subset: uberon_slim subset: vertebrate_core synonym: "vertebral centrum" EXACT [MA:0001457] synonym: "corpus vertebrae" RELATED [Wikipedia:Body_of_vertebra] synonym: "centra" EXACT PLURAL [PHENOSCAPE:ad] synonym: "centrum" EXACT [] synonym: "centrum of vertebra" EXACT [] synonym: "autocentrum" EXACT [ZFA:0000126] synonym: "corpus vertebrae (vertebrale)" EXACT [FMA:11945] synonym: "vertebral body" EXACT [FMA:11945] xref: FMA:11945 ! Body of vertebra xref: MA:0001457 ! vertebral body xref: AAO:0000697 ! centrum xref: ZFA:0000126 ! centrum xref: OpenCyc:Mx4rvXU4VpwpEbGdrcN5Y29ycA xref: ncithesaurus:Vertebral_Body ! Vertebral Body xref: OpenCyc:Mx4rvXU4VpwpEbGdrcN5Y29ycA ! vertebral body xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/63/Corpusvertebrae.png/200px-Corpusvertebrae.png is_a: UBERON:0004765 {source="VSAO"} ! skeletal element relationship: part_of UBERON:0002412 {source="MA"} ! vertebra xref: SCTID:361745008 ! Entire body of vertebra xref: SCTID:362867001 ! Entire centrum of vertebra xref: TAO:0000126 ! centrum xref: VSAO:0000183 ! vertebral centrum synonym: "corpus vertebrae" RELATED LATIN [Wikipedia:Body_of_vertebra] xref: http://upload.wikimedia.org/wikipedia/commons/6/63/Corpusvertebrae.png property_value: external_definition "Cylindrical body of bone, round or oval in cross section, which functionally replaces the notochord.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000697", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_2008"} property_value: external_definition "Centra are represented by mineralized, calcified, or ossified portions that surround the notochord. The autocentrum, present in Danio and all other living teleosts, is formed by direct ossification outside the elastica externa of the notochord (Arratia, 1999).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000126", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Skeletal element that surrounds the notochord.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000183", date_retrieved="2012-08-14", source="VSAO:curator"} synonym: "centre vertcébral@fr" RELATED [TAO:0000126] synonym: "pcérichorde@fr" RELATED [TAO:0000126] property_value: external_comment "The vertebral centrum may be cartilaginous, develop as cartilage but be replaced by bone or mineralized, or form directly through intramembranous ossification.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000183", date_retrieved="2012-09-06", source="Curator"} xref: UMLS:C0223084 [Term] id: UBERON:0009291 name: cartilaginous centrum of vertebra comment: cartilaginous centrum of vertebra[PMID:11746457] is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0001075 ! body of vertebra xref: SCTID:317278007 ! cartilaginous centrum of vertebra [Term] id: UBERON:0001076 name: spinous process of vertebra def: "The spinous process of a vertebra is directed backward and downward from the junction of the laminae (in humans), and serves for the attachment of muscles and ligaments. In animals without an erect stance, the process points upward and may slant forward or backward. Spinous processes are exaggerated in some animals, such as the extinct Dimetrodon and Spinosaurus, where they form a sail- or finback." [Wikipedia:Spinous_process] comment: Editor notes: todo - reconcile AAO def: "Small, posteriorly directed process at the posterior margin of each neural arch lamina; it is not a neural spine." [AAO:0000739] subset: uberon_slim subset: vertebrate_core synonym: "neural spine" RELATED [] synonym: "processus spinosus" EXACT [] synonym: "processus spinosus vertebrae" EXACT [] synonym: "vertebra spinous process" EXACT [] synonym: "spinous process" BROAD [] xref: FMA:11948 ! Spinous process of vertebra xref: MA:0001455 ! vertebra spinous process xref: ZFA:0001336 ! neural spine xref: AAO:0000705 ! neural_spine xref: AAO:0000739 ! spinous process xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/48/Processusspinosusvertebrae.png/200px-Processusspinosusvertebrae.png xref: EMAPA:25107 ! spinous process is_a: UBERON:0006061 ! process of vertebra relationship: part_of UBERON:0003861 ! neural arch xref: SCTID:264259004 ! Entire spinous process of vertebra xref: TAO:0001336 ! neural spine xref: http://upload.wikimedia.org/wikipedia/commons/4/48/Processusspinosusvertebrae.png property_value: external_definition "Elaboration of the mid-dorsal keel into a posterior or posterolateral process.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000705", date_retrieved="2012-06-20", source="AAO:Pugener_and_Maglia_2008"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of mid-dorsal keel (AAO:0000735)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000705", date_retrieved="2012-06-20"} property_value: external_definition "Small, posteriorly directed process at the posterior margin of each neural arch lamina; it is not a neural spine.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000739", date_retrieved="2012-06-20", source="AAO:Pugener_2002"} property_value: external_definition "Neural spines are extensions of neural arches dorsal to the neural canal in the median skeletogenous septum. Neural spines are typically unpaired median structures but can be paired in some instances, e.g., in the abdominal region of basal teleosts such as Leptolepis, Elops, Megalops, and Hiodon).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001336", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "neuracanthe@fr" RELATED [TAO:0001336] synonym: "cépine neurale@fr" RELATED [TAO:0001336] [Term] id: UBERON:0001078 name: pedicle of vertebra def: "The pedicles are two short, thick processes, which project backward, one on either side, from the upper part of the body, at the junction of its posterior and lateral surfaces. They connect the body of the spinal vertebra to the arch. [WP,unvetted]." [Wikipedia:Pedicle_of_vertebral_arch] subset: uberon_slim synonym: "pedicle of vertebral arch" EXACT [FMA:11950] synonym: "pediculus arcus vertebrae" EXACT LATIN [FMA:TA] synonym: "vertebral pedicle" EXACT [FMA:11950] synonym: "pedicle" BROAD [] xref: FMA:11950 ! Pedicle of vertebra xref: MA:0001458 ! vertebral pedicle xref: OpenCyc:Mx4rvYdjdJwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvYdjdJwpEbGdrcN5Y29ycA ! vertebral pedicle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d0/Pediculusarcusvertebrae.png/200px-Pediculusarcusvertebrae.png is_a: UBERON:0006061 ! process of vertebra relationship: part_of UBERON:0002412 ! vertebra xref: SCTID:277422007 ! Entire pedicle of vertebra xref: ncithesaurus:Pedicle_of_Vertebral_Arch ! pedicle of vertebral arch synonym: "pediculus arcus vertebrae, radix arcus vertebrae" RELATED LATIN [Wikipedia:Pedicle_of_vertebral_arch] xref: http://upload.wikimedia.org/wikipedia/commons/d/d0/Pediculusarcusvertebrae.png xref: UMLS:C0223080 [Term] id: UBERON:0011136 name: ligament of vertebral column def: "ligament that joins successive centra. Important in controlling the stiffness of the vertebral column when it flexes." [ISBN10:0073040584] synonym: "vertebral column ligament" EXACT [FMA:31892] synonym: "intervertebral ligament" BROAD [] intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: part_of UBERON:0001075 ! body of vertebra relationship: part_of UBERON:0001130 ! vertebral column xref: FMA:31892 ! ligament of vertebral column xref: SCTID:244590009 ! Entire intervertebral ligament [Term] id: UBERON:0001468 name: intervertebral joint def: "The joint between adjacent vertebral bodies. May be composed of the nucleus pulposus, annular ligament, and the anterior and posterior longitudinal ligaments." [http://www.medilexicon.com/medicaldictionary.php?t=87401] comment: AO notes: FMA has 'intervertebral joint' as a GAT, and has two distinct classes 'intervertebral symphysis' and 'intervertebral syndesmosis', but note that the latter do not connect the centra synonym: "joint of vertebral body" EXACT [FMA:25511] synonym: "vertebral joint" BROAD [] synonym: "inter-vertebral joint" EXACT [] synonym: "inter-centrum joint" EXACT [] synonym: "intervertebral symphysis" EXACT [FMA:25511] xref: FMA:25511 ! intervertebral symphysis xref: MA:0001514 ! joint of vertebral body is_a: UBERON:0002216 {source="FMA"} ! symphysis intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001075 {cardinality="2"} ! body of vertebra relationship: part_of UBERON:0001130 {source="FMA"} ! vertebral column relationship: connects UBERON:0001075 {notes="connects successive pairs of centra"} ! body of vertebra xref: SCTID:244512000 ! Entire intervertebral symphysis xref: ncithesaurus:Vertebral_Joint ! vertebral joint xref: UMLS:C1182940 [Term] id: UBERON:0011135 ! intervertebral cartilage name: intervertebral cartilage def: "A cartilage element that lies between two successive vertebral centra." [ISBN10:0073040584] is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: adjacent_to UBERON:0001075 {cardinality="2"} ! body of vertebra relationship: adjacent_to UBERON:0001075 {notes="between two centra"} ! body of vertebra relationship: part_of UBERON:0001468 {source="MA", source="FMA"} ! intervertebral joint xref: AAO:0000795 ! intervertebral cartilage property_value: external_definition "Block of cartilage, which usually ossifies, that lies between successive vertebral centra.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000795", date_retrieved="2012-06-20", source="AAO:Trueb_1973"} [Term] id: UBERON:0001066 name: intervertebral disk def: "A pad of fibrocartilage between the articular surfaces of two successive vertebral centra which has nucleus pulposus at its core." [Wikipedia:Intervertebral_disk, ISBN10:0073040584] comment: Taxon/Terminology notes: strictly speaking the term intervertebral disk [applies to intervertebral cartilage] whose gel-like core is nucleus puloposus, by this definition only in mammals subset: uberon_slim synonym: "intervertebral disc" EXACT [] synonym: "spinal disc" EXACT [Wikipedia:Spinal_disc] synonym: "intervertebral fibrocartilage" RELATED [BTO:0003625] synonym: "spinal disk" RELATED [BTO:0003625] xref: FMA:10446 ! Intervertebral disk xref: GAID:105 ! intervertebral disk xref: MA:0000110 ! intervertebral disc xref: OpenCyc:Mx4rv11AcpwpEbGdrcN5Y29ycA xref: ncithesaurus:Intervertebral_Disc ! Intervertebral Disc xref: BTO:0003625 ! intervertebral disc xref: EFO:0001370 ! intervertebral disc xref: OpenCyc:Mx4rv11AcpwpEbGdrcN5Y29ycA ! intervertebral disk xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/92/Gray301.png/200px-Gray301.png xref: MESH:A02.165.410 ! intervertebral disk intersection_of: UBERON:0011135 ! intervertebral cartilage intersection_of: has_part UBERON:0002242 ! nucleus pulposus synonym: "discus intervertebralis" EXACT LATIN [FMA:TA, FMA:10446] xref: SCTID:244570000 ! Entire intervertebral disc xref: UMLS:C0021815 [Term] id: UBERON:0002242 name: nucleus pulposus def: "a jelly-like connective tissue in the middle of the spinal disc. It is the remnant of the notochord. It functions to distribute hydraulic pressure in all directions within each disc under compressive loads. The nucleus pulposus consists of chondrocytes, collagen fibrils, and proteoglycan aggrecans that have hyaluronic long chains which attract water. Attached to each hyaluronic chain are side chains of chondroitin sulfate and keratan sulfate[WP]." [Wikipedia:Nucleus_pulposus] comment: AO notes: we group two FMA classes together subset: uberon_slim synonym: "nucleus propulsus of intervertebral disk" RELATED [Wikipedia:Nucleus_pulposus] synonym: "nucleus pulposus (diskus intervertebralis)" EXACT [FMA:13550] synonym: "nucleus propulsus" RELATED [Wikipedia:Nucleus_pulposus] synonym: "pulpy nucleus" EXACT [] xref: FMA:76703 ! Nucleus pulposus xref: FMA:13550 ! nucleus pulposus of intervertebral disk xref: MA:0000112 ! nucleus pulposus xref: BTO:0003626 ! nucleus pulposus xref: SCTID:316586000 ! Entire nucleus pulposus of intervertebral disc xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Cervical_vertebra_english.png/200px-Cervical_vertebra_english.png is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0001066 ! intervertebral disk relationship: develops_from UBERON:0002328 {source="Wikipedia", editor="mah", source="ISBN10:0073040584"} ! notochord xref: http://upload.wikimedia.org/wikipedia/commons/d/d9/Cervical_vertebra_english.png synonym: "nucleus pulposus of intervertebral disk" RELATED [FMA:13550] [Term] id: UBERON:0004715 name: annulus fibrosus disci intervertebralis def: "The ring of fibrocartilage and fibrous tissue forming the circumference of the intervertebral disc; surrounds the nucleus pulposus, which is prone to herniation when the annulus fibrosus is compromised." [BTO:0003629, Wikipedia:Annulus_fibrosus_disci_intervertebralis] synonym: "annulus fibrosus of intervertebral disc" RELATED [BTO:0003629] synonym: "fibrous ring of intervertebral disc" RELATED [BTO:0003629] synonym: "anulus fibrosus of intervertebral disk" EXACT [FMA:13551] synonym: "annulus fibrosus" BROAD [MA:0000111] synonym: "anulus fibrosus (diskus intervertebralis)" EXACT [FMA:13551] xref: Wikipedia:Annulus_fibrosus_disci_intervertebralis ! annulus fibrosus disci intervertebralis xref: BTO:0003629 ! annulus fibrosus disci intervertebralis xref: MA:0000111 ! annulus fibrosus xref: FMA:13551 ! anulus fibrosus of intervertebral disk xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Cervical_vertebra_english.png/200px-Cervical_vertebra_english.png intersection_of: UBERON:0006444 ! annulus fibrosus intersection_of: part_of UBERON:0001066 ! intervertebral disk disjoint_from: UBERON:0006008 ! fibrous ring of heart xref: http://upload.wikimedia.org/wikipedia/commons/d/d9/Cervical_vertebra_english.png [Term] id: UBERON:0001067 name: vertebral arch joint def: "a synovial joint between the superior articular process of one vertebra and the inferior articular process of the vertebra directly above it. There are two facet joints in each spinal motion segment[WP]." [Wikipedia:Zygapophysial_joint] subset: uberon_slim synonym: "spinal facet joint" EXACT [HP:0008482] synonym: "facet joint" EXACT [] synonym: "joint of vertebral arch" EXACT [] synonym: "joint of vertebral articular process" EXACT [] synonym: "zygapophyseal joint" EXACT [] synonym: "zygapophysial joint" EXACT [] xref: FMA:10447 ! Vertebral arch joint xref: GAID:275 ! zygapophyseal joint xref: MA:0001513 ! joint of vertebral arch xref: ncithesaurus:Facet_Joint ! Facet Joint xref: OpenCyc:Mx4rvorHEpwpEbGdrcN5Y29ycA ! vertebral arch joint xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/Gray90.png/200px-Gray90.png xref: MESH:A02.835.583.979 ! zygapophyseal joint intersection_of: UBERON:0002217 ! synovial joint intersection_of: connects UBERON:0001079 ! superior articular process of vertebra intersection_of: connects UBERON:0001080 ! inferior articular process of vertebra relationship: part_of UBERON:0003861 ! neural arch xref: SCTID:89836005 ! Entire zygapophyseal joint synonym: "articulationes zygapophysiales" RELATED LATIN [Wikipedia:Zygapophysial_joint] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray90.png xref: UMLS:C0224521 [Term] id: UBERON:0010358 name: arch of centrum of vertebra comment: AO notes: Note that humans do not have hemal arches, so VA=NA for FMA synonym: "arch of vertebra" NARROW [FMA:11946] synonym: "arcus vertebrae (vertebralis)" NARROW [FMA:11946] synonym: "vertebra arch" NARROW [MA:0001453] synonym: "vertebral arch" NARROW [FMA:11946] is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0002412 {source="FMA"} ! vertebra xref: FMA:11946 ! vertebral arch (also: UBERON:0003861 'neural arch') xref: VHOG:0001670 ! vertebra neural arch (also: UBERON:0003861 'neural arch') property_value: homology_notes " (...) certain common components [of vertebral structure] are found in nearly all vertebrate. A representative vertebra has a vertebral arch or neural arch, which extends dorsally around the spinal cord.[well established][VHOG]" xsd:string {external_class="VHOG:0001670", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.270", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006065 name: hemal arch def: "Bony canal attached to the ventral surface or the vertebral centrum that encloses and protects the caudal artery and vein ventrally. The arch consists of right and left halves, which are fused ventrally to give a V- or Y-shape to the ventral aspect of the vertebra[AAO]. Hemal arches extend ventrally from the centra of caudal and transitional vertebrae to enclose the caudal artery and vein. In cyprinids, the hemal arch forms directly in membrane bone[ZFA]." [ZFIN:curator, Wikipedia:Haemal_arch, AAO:0000726] comment: Taxon notes: fish, most reptiles, some birds, and some mammals with long tails.[WP] synonym: "haemal arch" EXACT [AAO:0000726, ZFA:0000519] synonym: "ventral arcocentrum" EXACT [ZFA:0000519] synonym: "ventral arch" RELATED [AAO:0000726] synonym: "chevron" RELATED [PHENOSCAPE:ad] xref: ZFA:0000519 ! hemal arch xref: AAO:0000726 ! haemal arch is_a: UBERON:0010358 ! vertebral arch is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0001095 ! caudal vertebra xref: TAO:0000519 ! hemal arch property_value: external_definition "Bony canal attached to the ventral surface or the vertebral centrum that encloses and protects the caudal artery and vein ventrally. The arch consists of right and left halves, which are fused ventrally to give a V- or Y-shape to the ventral aspect of the vertebra.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000726", date_retrieved="2012-06-20", source="AAO:Pugener_2002"} property_value: external_definition "Hemal arches extend ventrally from the centra of caudal and transitional vertebrae to enclose the caudal artery and vein. In cyprinids, the hemal arch forms directly in membrane bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000519", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from basiventral (TAO:0001361)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000519", date_retrieved="2012-08-14"} [Term] id: UBERON:0006063 ! cartilaginous neural arch name: cartilaginous neural arch def: "One of the cartilaginous structures surrounding the embryonic spinal cord, formed by the dorsal growth of the dorsolateral arcualia; it is the primordium of the vertebral arch." [BTO:0001763] xref: BTO:0001763 ! neural arch is_a: UBERON:0010358 ! vertebral arch relationship: has_part UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0003861 name: neural arch def: "posterior part of a vertebra that consists of a pair of pedicles and a pair of laminae, and supports seven processes: four articular processes, two transverse processes one spinous process[WP]. ZFA: A neural arch encloses the neural canal and typically meets its partner to form a neural spine. The neural arch can be a replacement ossification of the basidorsal cartilage or can form directly in membrane bone." [Wikipedia:Vertebral_arch] comment: Taxon notes: tiny neural arches present in Hagfish (which lack a true vertebraal column). subset: vertebrate_core synonym: "vertebra neural arch" BROAD SENSU [MA:0001453] synonym: "vertebra dorsal arch" RELATED [MA:0001453] synonym: "arcus vertebrae (vertebralis)" EXACT [FMA:11946] synonym: "arcus vertebra" EXACT [Wikipedia:Vertebral_arch] synonym: "arcus vertebrae" EXACT PLURAL [Wikipedia:Vertebral_arch] synonym: "dorsal arcocentrum" EXACT [ZFA:0001066] xref: VHOG:0001670 ! vertebra neural arch (also: UBERON:0010358 'arch of centrum of vertebra') xref: MA:0001453 ! vertebra neural arch xref: FMA:11946 ! vertebral arch (also: UBERON:0010358 'arch of centrum of vertebra') xref: ZFA:0001066 ! neural arch xref: OpenCyc:Mx4rwKYHvZwpEbGdrcN5Y29ycA ! vertebral arch xref: MA:0001453 ! vertebra arch xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray82.png/200px-Gray82.png xref: AAO:0000725 ! neural arch xref: EFO:0003618 ! neural arch is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0010358 ! vertebral arch relationship: develops_from UBERON:0006063 ! cartilaginous neural arch xref: ncithesaurus:Arch_of_the_Vertebra ! Arch of the Vertebra xref: SCTID:317373001 ! Entire arch of vertebra xref: TAO:0001066 ! neural arch synonym: "arcus vertebrae" RELATED LATIN [Wikipedia:Vertebral_arch] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray82.png property_value: external_definition "Bony arch perched on the vertebral centrum; successive arches enclose the neural canal that surrounds and protects the spinal cord dorsally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000725", date_retrieved="2012-06-20", source="AAO:Pugener_2002"} property_value: external_definition "A neural arch encloses the neural canal and typically meets its partner to form a neural spine. The neural arch can be a replacement ossification of the basidorsal cartilage or can form directly in membrane bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001066", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from basidorsal (TAO:0001060)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001066", date_retrieved="2012-08-14"} property_value: homology_notes " (...) certain common components [of vertebral structure] are found in nearly all vertebrate. A representative vertebra has a vertebral arch or neural arch, which extends dorsally around the spinal cord.[well established][VHOG]" xsd:string {external_class="VHOG:0001670", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.270", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0223076 [Term] id: UBERON:0006061 name: process of vertebra def: "A process projection from a part of the vertebra such as centrum or arches. Examples: transverse process, diapophyses, parapophyses, and zygapophyses (both the cranial zygapophyses and the caudal zygapophyses)." [Wikipedia:Vertebral_column#Structure_of_individual_vertebrae] synonym: "vertebral process" EXACT [FMA:24530] synonym: "vertebra process" EXACT [] xref: FMA:24530 ! process of vertebra is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0002412 ! vertebra [Term] id: UBERON:0006062 ! articular process of vertebra name: articular process of vertebra def: "Paired processes at the cephalic and caudal ends of the neural arch. They function as interlocking structures between adjacent vertebrae, and limit dorsoventral flexion and lateral movement of the column in the trunk region[AAO]. The articular processes or zygapophyses of a vertebra, in human anatomy contain two superior and two inferior, spring from the junctions of the pedicles and laminae. These stick out of an end of a vertebra to lock with a zygapophysis on the next vertebra, to make the backbone more stable. The superior processes project upward from a lower vertebra, and their articular surfaces are directed more or less backward. The inferior processes project downward from a higher vertebra, and their articular surfaces are directed more or less forward and outward. The articular surfaces are coated with hyaline cartilage." [Wikipedia:Articular_processes, AAO:Pugener_and_Maglia_2008] comment: todo - class as endochondral bone, check species subset: vertebrate_core synonym: "articular process" BROAD [Wikipedia:Articular_processes] synonym: "zygapophysis" EXACT [Wikipedia:Articular_processes] synonym: "processus articularis (zygapophysis)" EXACT [FMA:11952] xref: FMA:11952 ! articular process of vertebra xref: AAO:0000710 ! zygapophysis xref: ZFA:0001603 ! intercalarium articulating process is_a: UBERON:0006061 ! process of vertebra relationship: in_lateral_side_of UBERON:0002412 ! vertebra xref: SCTID:317570004 ! Entire articular process of vertebra xref: TAO:0001549 ! intercalarium articulating process synonym: "p. articularis inferior vertebrae, p. articularis superior vertebrae," RELATED LATIN [Wikipedia:Articular_processes] xref: http://upload.wikimedia.org/wikipedia/commons/3/3e/Processusarticularissuperiorvertebrae.png property_value: external_definition "Paired processes at the cephalic and caudal ends of the neural arch. They function as interlocking structures between adjacent vertebrae, and limit dorsoventral flexion and lateral movement of the column in the trunk region.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000710", date_retrieved="2012-06-20", source="AAO:Pugener_and_Maglia_2008"} synonym: "intercalarium articulating process" RELATED [TAO:0001549] [Term] id: UBERON:0001079 ! superior articular process of vertebra name: superior articular process of vertebra def: "Paired processes at the cephalic end of the neural arch. The articular facets of the prezygapophyses face dorsomedially and articulate with the lateroventrally facing facets of the postzygapophyses of the preceding vertebra." [AAO:Pugener_and_Maglia_2008] comment: TODO - add distinct classes for hemal vs neural? subset: vertebrate_core synonym: "cranial articular process of vertebra" EXACT [] synonym: "prezygapophysis" EXACT [] synonym: "processus articularis superior" EXACT [] synonym: "vertebra cranial articular process" EXACT [] synonym: "neural prezygapophysis" EXACT [ZFA:0001325] synonym: "neural prezygopophyses" EXACT [ZFA:0001325] xref: FMA:11953 ! Superior articular process of vertebra xref: MA:0001452 ! vertebra cranial articular process xref: AAO:0000703 ! prezygapophysis xref: ZFA:0001325 ! neural prezygapophysis is_a: UBERON:0006062 ! articular process of vertebra xref: SCTID:42424006 ! Entire superior articular process of vertebra xref: http://www.informatics.jax.org/cookbook/figures/figure20.shtml xref: TAO:0001325 ! neural prezygapophysis property_value: external_definition "Paired, anteromedially directed processes from the neural arches, ligamentously joined to the postzygapophyses of the preceding vertebra.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001325", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "neural prezygapophyses" RELATED PLURAL [TAO:0001325] [Term] id: UBERON:0001080 ! inferior articular process of vertebra name: inferior articular process of vertebra def: "Paired processes at the caudal end of the neural arch. The articular facets of the postzygapophyses face lateroventrally and articulate with the dorsomedially facing facets of the prezygapophyses of the succeeding vertebra." [AAO:LAP] comment: TODO - add distinct classes for hemal vs neural? subset: vertebrate_core synonym: "processus obliquus posterior" RELATED [AAO:0000702] synonym: "caudal articular process of vertebra" EXACT [] synonym: "postzygapophysis" EXACT [] synonym: "processus articularis inferior" EXACT [] synonym: "vertebra caudal articular process" EXACT [] synonym: "neural postzygapophysis" NARROW [ZFA:0000681] synonym: "neural postzygopophysis" EXACT [ZFA:0000681] xref: FMA:11954 ! Inferior articular process of vertebra xref: MA:0001451 ! vertebra caudal articular process xref: AAO:0000702 ! postzygapophysis xref: ZFA:0000681 ! neural postzygapophysis is_a: UBERON:0006062 ! articular process of vertebra xref: SCTID:30079000 ! Entire inferior articular process of vertebra xref: TAO:0000681 ! neural postzygapophysis property_value: external_definition "Paired, dorsomedially directed processes on the posterior ends of the centra, ligamentously joined to the neural prezygapophyses of the immediately posterior vertebra.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000681", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "neural postzygapophyses" RELATED PLURAL [TAO:0000681] synonym: "neural postzygopophyses" RELATED [TAO:0000681] [Term] id: UBERON:0011200 name: sacrococcygeal symphysis def: "The sacrococcygeal symphysis (sacrococcygeal articulation, articulation of the sacrum and coccyx) is an amphiarthrodial joint, formed between the oval surface at the apex of the sacrum, and the base of the coccyx. It is a slightly moveable joint which is frequently, partially or completely, obliterated in old age, homologous with the joints between the bodies of the vertebrae." [Wikipedia:Sacrococcygeal_symphysis] synonym: "sacrococcygeal joint" RELATED [Wikipedia:Sacrococcygeal_symphysis] is_a: UBERON:0001468 {source="FMA"} ! intervertebral joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001350 ! coccyx intersection_of: connects UBERON:0003690 ! sacrum xref: FMA:16210 ! sacrococcygeal joint xref: ncithesaurus:Sacrococcygeal_Joint ! sacrococcygeal joint synonym: "sacrococcygeal joint" EXACT [FMA:16210] xref: http://upload.wikimedia.org/wikipedia/commons/7/7f/Gray320.png xref: UMLS:C0224593 [Term] id: UBERON:0001082 name: epicardium of ventricle def: "The external layer of the ventricle bounding the ventricular myocardium. It is formed by a single layer of mesothelial cells supported by a basal lamina, and imbricated with collagen, fibroblasts, and vascular structures in the subepicardial space. Hu et al. 2001.." [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "ventricular epicardium" EXACT [] synonym: "cardiac ventricle epicardium" EXACT [OBOL:automatic] synonym: "cardiac ventricle heart epicardium" EXACT [OBOL:automatic] synonym: "cardiac ventricle visceral serous pericardium of heart" EXACT [OBOL:automatic] synonym: "epicardium of cardiac ventricle" EXACT [OBOL:automatic] synonym: "epicardium of heart ventricle" EXACT [OBOL:automatic] synonym: "epicardium of lower chamber of heart" EXACT [OBOL:automatic] synonym: "epicardium of ventricle of heart" EXACT [OBOL:automatic] synonym: "heart epicardium of cardiac ventricle" EXACT [OBOL:automatic] synonym: "heart epicardium of heart ventricle" EXACT [OBOL:automatic] synonym: "heart epicardium of lower chamber of heart" EXACT [OBOL:automatic] synonym: "heart epicardium of ventricle of heart" EXACT [OBOL:automatic] synonym: "heart ventricle epicardium" EXACT [OBOL:automatic] synonym: "heart ventricle heart epicardium" EXACT [OBOL:automatic] synonym: "heart ventricle visceral serous pericardium of heart" EXACT [OBOL:automatic] synonym: "lower chamber of heart epicardium" EXACT [OBOL:automatic] synonym: "lower chamber of heart heart epicardium" EXACT [OBOL:automatic] synonym: "lower chamber of heart visceral serous pericardium of heart" EXACT [OBOL:automatic] synonym: "ventricle of heart epicardium" EXACT [OBOL:automatic] synonym: "ventricle of heart heart epicardium" EXACT [OBOL:automatic] synonym: "ventricle of heart visceral serous pericardium of heart" EXACT [OBOL:automatic] synonym: "visceral serous pericardium of heart of cardiac ventricle" EXACT [OBOL:automatic] synonym: "visceral serous pericardium of heart of heart ventricle" EXACT [OBOL:automatic] synonym: "visceral serous pericardium of heart of lower chamber of heart" EXACT [OBOL:automatic] synonym: "visceral serous pericardium of heart of ventricle of heart" EXACT [OBOL:automatic] xref: FMA:12150 ! Epicardium of ventricle xref: TAO:0005058 ! ventricular epicardium xref: ZFA:0005058 ! ventricular epicardium is_a: UBERON:0002348 ! epicardium intersection_of: UBERON:0002348 ! epicardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: external_definition "The external layer of the ventricle bounding the ventricular myocardium. It is formed by a single layer of mesothelial cells supported by a basal lamina, and imbricated with collagen, fibroblasts, and vascular structures in the subepicardial space. Hu et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005058", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005983 ! heart layer name: heart layer def: "the laminar structure of the heart" [MP:0010545] intersection_of: UBERON:0004923 ! organ component layer intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0004123 name: myocardial layer synonym: "myocardium layer" EXACT [] synonym: "layer of myocardium" EXACT [] xref: MA:0000080 ! myocardium layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: part_of UBERON:0002349 ! myocardium def: "An organ component layer that is part of a myocardium." [OBOL:automatic] [Term] id: UBERON:0004125 name: myocardial compact layer def: "outer dense layer of the myocardium uniting the epicardium and myocardium[MP]." [MP:0004056] synonym: "myocardium compact layer" EXACT [MA:0002865] xref: MA:0002865 ! myocardium compact layer is_a: UBERON:0004123 ! myocardium layer [Term] id: UBERON:0002349 name: myocardium def: "middle muscular layer of the heart wall[M-W]. Muscle layer of organ which has as its parts the myocardium proper and the conducting system of the heart[FMA]." [Wikipedia:Myocardium] comment: TODO - check 'Myocardum proper' in FMA. We superclass the more generic class for now. FMA has is_a muscle layer - should we add this? ZFA and BTO both have is_a 'cardiac muscle' (tissue?). But in U we also follow FMA and have cardiac muscle tissue of myocardium (there is also Fibrocollagenous connective tissue of myocardium), which would be identical (see issue-10). Note that GO also treats left/right ventricular cardiac muscle tissue synonymous with ventricular myocardium subset: uberon_slim subset: vertebrate_core synonym: "cardiac muscle" RELATED [ZFA:0001319] synonym: "heart myocardium" EXACT [] synonym: "muscle of heart" EXACT [FMA:9462] synonym: "heart muscle " RELATED [ZFA:0001319] xref: BTO:0000901 xref: EFO:0000819 ! myocardium xref: FMA:9462 ! Myocardium xref: GAID:173 ! myocardium xref: MA:0000164 ! myocardium xref: MAT:0000453 ! myocardium xref: ncithesaurus:Myocardium xref: OpenCyc:Mx4ro36AFrCvEduAAAAOpmP6tw xref: TAO:0001319 ! myocardium xref: XAO:0000065 ! myocardium xref: ZFA:0001319 ! myocardium xref: VHOG:0000083 ! heart myocardium xref: galen:Myocardium ! myocardium xref: OpenCyc:Mx4ro36AFrCvEduAAAAOpmP6tw ! myocardium xref: RETIRED_EHDAA2:0001220 ! myocardium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Glanzstreifen.jpg/200px-Glanzstreifen.jpg xref: MESH:A02.633.580 ! myocardium xref: EV:0100022 ! myocardium is_a: UBERON:0005983 ! heart layer relationship: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000383 ! musculature of body xref: AAO:0010410 ! myocardium xref: SCTID:362012001 ! Entire myocardium xref: EHDAA2:0004150 ! heart muscle property_value: external_definition "The middle layer of the heart, consisting of cardiac muscle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010410", date_retrieved="2012-06-20", source="AAO:BJB"} synonym: "heart muscle" RELATED [FMA:9462] property_value: external_definition "Robust muscular tunic of the heart which forms the basic part of its walls. Its external surface is covered by the pericardium and its internal one by the endocardium. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000083", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "myocardial" xsd:string xref: UMLS:C0027061 [Term] id: UBERON:0002511 ! trabecula carnea name: trabecula carnea def: "The trabeculae carneae (columnae carneae, or fleshy beams), are rounded or irregular muscular columns which project from the inner surface of the right and left ventricles of the heart.[1] They should not be confused with the pectinate muscles, which are present in the right[1] and left atria only. They are of three kinds: * some are attached along their entire length on one side and merely form prominent ridges,* others are fixed at their extremities but free in the middle, * while a third set, the papillary muscles are continuous by their bases with the wall of the ventricle, while their apices give origin to the chordæ tendineæ which pass to be attached to the segments of both the mitral valve and the tricuspid valve. The purpose of the trabeculae carneae is most likely to prevent suction that would occur with a flat surfaced membrane and thus impair the heart's ability to pump efficiently. The trabeculae carneae also serve a similar function to papillary muscles in that their contraction pulls on the chordae tendineae, preventing inversion of the mitral (bicuspid) and tricuspid valves, that is, their bulging towards the atrial chambers, which would lead to subsequent leakage of the blood into the atria. So by the action of papillary muscles on the atrioventricular valves, backflow of the blood from the ventricles into the atria is prevented[WP]." [Wikipedia:Trabeculae_carneae] comment: Note that WP states they are ventricular, but MP has classes for atrial ventricular carnea. synonym: "heart trabecula" RELATED [GO:0060347] synonym: "cardiac trabecula" RELATED [GO:0060347] synonym: "trabecula of heart" RELATED [] synonym: "ventricle trabecula carnea" EXACT [MA:0002831] synonym: "ventricular trabecula" RELATED [MA:0002831] xref: FMA:7269 ! Trabecula carnea xref: MA:0002831 ! trabecula carnea xref: EMAPA:18626 ! trabeculae carneae is_a: UBERON:0000440 ! trabecula relationship: part_of UBERON:0000948 ! heart synonym: "trabeculae carneae cordis" RELATED LATIN [Wikipedia:Trabeculae_carneae] xref: SCTID:118755002 ! Trabeculae carneae cordis [Term] id: UBERON:0004124 ! myocardium trabecular layer name: myocardium trabecular layer def: "The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]." [ZFA:0005059] subset: vertebrate_core synonym: "trabecular layer" EXACT [ZFA:0005059] synonym: "myocardial trabecular layer" EXACT [] xref: ZFA:0005059 ! trabecular layer xref: MA:0002866 ! myocardium trabecular layer xref: EFO:0003706 ! trabecular layer is_a: UBERON:0004123 ! myocardium layer relationship: has_part CL:0000187 ! muscle cell xref: TAO:0005059 ! trabecular layer property_value: external_definition "The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the the endocardium. Unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae of the zebrafish have more strut-like character, and are more uniform without apparent regional differences Hu et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005059", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "trabeculae" RELATED [TAO:0005059] [Term] id: UBERON:0004126 name: trabecular layer of ventricle comment: todo - check FMA subset: vertebrate_core synonym: "trabecular cardiac ventricle muscle" EXACT [GO:0003222] synonym: "ventricular trabecular myocardium" EXACT [GO:0003222] synonym: "myocardium of region of ventricle" EXACT [FMA:83511] xref: ZFA:0005060 ! trabecular layer of ventricle xref: FMA:83511 ! Myocardium of region of ventricle intersection_of: UBERON:0004124 ! myocardium trabecular layer intersection_of: part_of UBERON:0002082 ! cardiac ventricle xref: TAO:0005060 ! trabecular layer of ventricle def: "A myocardium trabecular layer that is part of a cardiac ventricle." [OBOL:automatic] relationship: part_of UBERON:0001083 {source="reference_0000032"} ! myocardium of ventricle relationship: part_of UBERON:0004784 {source="reference_0000032"} ! heart ventricle wall [Term] id: UBERON:0006570 name: trabecula carnea of right ventricle synonym: "trabeculae carneae (ventriculus dexter)" EXACT [FMA:7270] xref: FMA:7270 ! trabecula carnea of right ventricle intersection_of: UBERON:0002511 ! trabecula carnea intersection_of: part_of UBERON:0002080 ! right ventricle xref: SCTID:192373001 ! Entire trabecula carnea of right ventricle def: "A trabecula carnea that is part of a heart right ventricle." [OBOL:automatic] [Term] id: UBERON:0006571 name: trabecula carnea of left ventricle synonym: "trabeculae carneae (ventriculus sinister)" EXACT [FMA:7271] xref: FMA:7271 ! trabecula carnea of left ventricle intersection_of: UBERON:0002511 ! trabecula carnea intersection_of: part_of UBERON:0002084 ! left ventricle xref: SCTID:190344008 ! Entire trabecula carnea of left ventricle def: "A trabecula carnea that is part of a heart left ventricle." [OBOL:automatic] [Term] id: UBERON:0006828 name: trabecula carnea of atrium def: "the supporting bundles of muscular fibers lining the walls of the atria[MP]." [MP:0010581] comment: Dubious: Not present in any AO. Note that WP states that trabecular carnea are ventricular and 'They should not be confused with the pectinate muscles, which are present in the right[1] and left atria only' intersection_of: UBERON:0002511 ! trabecula carnea intersection_of: part_of UBERON:0002081 ! cardiac atrium [Term] id: UBERON:0003452 name: trabecula carnea cardiac muscle tissue def: "A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle" EXACT [OBOL:automatic] synonym: "cardiac muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle of heart muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle of heart textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of heart muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of heart myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of muscle of heart of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of heart muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of heart myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of muscle of heart of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea heart muscle muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea heart muscle textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea heart myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea heart myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle of heart muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle of heart textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of heart muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of heart myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of muscle of heart" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of heart muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of heart myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of muscle of heart" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of myocardium" EXACT [OBOL:automatic] xref: MA:0002833 ! trabecula carnea cardiac muscle tissue xref: FMA:84428 ! Cardiac muscle tissue of trabecula carnea intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002511 ! trabecula carnea [Term] id: UBERON:0004127 ! compact layer of ventricle name: compact layer of ventricle def: "The outer layer the ventricular myocardium, muscle fibers are arranged in a compact form and involved the entire ventricle." [ZFA:0005062] synonym: "ventricle myocardium compact zone" EXACT [MP:0010556] synonym: "ventricular myocardial compact layer" EXACT [MP:0010556] synonym: "ventricular myocardial compact zone" EXACT [MP:0010556] synonym: "compact cardiac ventricle muscle" EXACT [] synonym: "ventricular compact myocardium" EXACT [] xref: ZFA:0005062 ! compact layer of ventricle intersection_of: UBERON:0004125 ! myocardial compact layer intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0001083 {source="ZFA"} ! myocardium of ventricle xref: TAO:0005062 ! compact layer of ventricle property_value: external_definition "The outer layer the ventricular myocardium, muscle fibers are arranged in a compact form and involved the entire ventricle.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005062", date_retrieved="2012-08-14", source="ZFIN:curator"} relationship: part_of UBERON:0004784 {source="reference_0000032"} ! heart ventricle wall [Term] id: UBERON:0001083 name: myocardium of ventricle def: "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer." [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "ventricle myocardium" EXACT [] synonym: "ventricular myocardium" EXACT [] synonym: "cardiac muscle of cardiac ventricle" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart ventricle" EXACT [OBOL:automatic] synonym: "cardiac muscle of lower chamber of heart" EXACT [OBOL:automatic] synonym: "cardiac muscle of ventricle of heart" EXACT [OBOL:automatic] synonym: "cardiac ventricle cardiac muscle" EXACT [OBOL:automatic] synonym: "cardiac ventricle heart muscle" EXACT [OBOL:automatic] synonym: "cardiac ventricle heart myocardium" EXACT [OBOL:automatic] synonym: "cardiac ventricle muscle of heart" EXACT [OBOL:automatic] synonym: "cardiac ventricle myocardium" EXACT [OBOL:automatic] synonym: "heart muscle of cardiac ventricle" EXACT [OBOL:automatic] synonym: "heart muscle of heart ventricle" EXACT [OBOL:automatic] synonym: "heart muscle of lower chamber of heart" EXACT [OBOL:automatic] synonym: "heart muscle of ventricle of heart" EXACT [OBOL:automatic] synonym: "heart myocardium of cardiac ventricle" EXACT [OBOL:automatic] synonym: "heart myocardium of heart ventricle" EXACT [OBOL:automatic] synonym: "heart myocardium of lower chamber of heart" EXACT [OBOL:automatic] synonym: "heart myocardium of ventricle of heart" EXACT [OBOL:automatic] synonym: "heart ventricle cardiac muscle" EXACT [OBOL:automatic] synonym: "heart ventricle heart muscle" EXACT [OBOL:automatic] synonym: "heart ventricle heart myocardium" EXACT [OBOL:automatic] synonym: "heart ventricle muscle of heart" EXACT [OBOL:automatic] synonym: "heart ventricle myocardium" EXACT [OBOL:automatic] synonym: "lower chamber of heart cardiac muscle" EXACT [OBOL:automatic] synonym: "lower chamber of heart heart muscle" EXACT [OBOL:automatic] synonym: "lower chamber of heart heart myocardium" EXACT [OBOL:automatic] synonym: "lower chamber of heart muscle of heart" EXACT [OBOL:automatic] synonym: "lower chamber of heart myocardium" EXACT [OBOL:automatic] synonym: "muscle of heart of cardiac ventricle" EXACT [OBOL:automatic] synonym: "muscle of heart of heart ventricle" EXACT [OBOL:automatic] synonym: "muscle of heart of lower chamber of heart" EXACT [OBOL:automatic] synonym: "muscle of heart of ventricle of heart" EXACT [OBOL:automatic] synonym: "myocardium of cardiac ventricle" EXACT [OBOL:automatic] synonym: "myocardium of heart ventricle" EXACT [OBOL:automatic] synonym: "myocardium of lower chamber of heart" EXACT [OBOL:automatic] synonym: "myocardium of ventricle of heart" EXACT [OBOL:automatic] synonym: "ventricle of heart cardiac muscle" EXACT [OBOL:automatic] synonym: "ventricle of heart heart muscle" EXACT [OBOL:automatic] synonym: "ventricle of heart heart myocardium" EXACT [OBOL:automatic] synonym: "ventricle of heart muscle of heart" EXACT [OBOL:automatic] synonym: "ventricle of heart myocardium" EXACT [OBOL:automatic] xref: FMA:12151 ! Myocardium of ventricle xref: VHOG:0000604 ! ventricle myocardium xref: MA:0000082 ! ventricle myocardium xref: TAO:0005061 ! ventricular myocardium xref: ZFA:0005061 ! ventricular myocardium xref: EFO:0003088 ! ventricular myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle xref: SCTID:192084000 ! Entire myocardium of ventricle property_value: external_definition "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer Hu et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005061", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "ventricle cardiac muscle" RELATED [VHOG:0000604] property_value: homology_notes "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000604", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.481", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: part_of UBERON:0004784 {source="reference_0000032"} ! heart ventricle wall [Term] id: UBERON:0002302 name: myocardium of atrium def: "A myocardium that is part of a cardiac atrium [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "atrial myocardium" EXACT [] synonym: "atrium myocardium" EXACT [] synonym: "Cardiac atria cardiac muscle" EXACT [OBOL:automatic] synonym: "Cardiac atria heart muscle" EXACT [OBOL:automatic] synonym: "Cardiac atria heart myocardium" EXACT [OBOL:automatic] synonym: "Cardiac atria muscle of heart" EXACT [OBOL:automatic] synonym: "Cardiac atria myocardium" EXACT [OBOL:automatic] synonym: "atrium of heart cardiac muscle" EXACT [OBOL:automatic] synonym: "atrium of heart heart muscle" EXACT [OBOL:automatic] synonym: "atrium of heart heart myocardium" EXACT [OBOL:automatic] synonym: "atrium of heart muscle of heart" EXACT [OBOL:automatic] synonym: "atrium of heart myocardium" EXACT [OBOL:automatic] synonym: "cardiac atrium cardiac muscle" EXACT [OBOL:automatic] synonym: "cardiac atrium heart muscle" EXACT [OBOL:automatic] synonym: "cardiac atrium heart myocardium" EXACT [OBOL:automatic] synonym: "cardiac atrium muscle of heart" EXACT [OBOL:automatic] synonym: "cardiac atrium myocardium" EXACT [OBOL:automatic] synonym: "cardiac muscle of Cardiac atria" EXACT [OBOL:automatic] synonym: "cardiac muscle of atrium of heart" EXACT [OBOL:automatic] synonym: "cardiac muscle of cardiac atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart atrium" EXACT [OBOL:automatic] synonym: "heart atrium cardiac muscle" EXACT [OBOL:automatic] synonym: "heart atrium heart muscle" EXACT [OBOL:automatic] synonym: "heart atrium heart myocardium" EXACT [OBOL:automatic] synonym: "heart atrium muscle of heart" EXACT [OBOL:automatic] synonym: "heart atrium myocardium" EXACT [OBOL:automatic] synonym: "heart muscle of Cardiac atria" EXACT [OBOL:automatic] synonym: "heart muscle of atrium of heart" EXACT [OBOL:automatic] synonym: "heart muscle of cardiac atrium" EXACT [OBOL:automatic] synonym: "heart muscle of heart atrium" EXACT [OBOL:automatic] synonym: "heart myocardium of Cardiac atria" EXACT [OBOL:automatic] synonym: "heart myocardium of atrium of heart" EXACT [OBOL:automatic] synonym: "heart myocardium of cardiac atrium" EXACT [OBOL:automatic] synonym: "heart myocardium of heart atrium" EXACT [OBOL:automatic] synonym: "muscle of heart of Cardiac atria" EXACT [OBOL:automatic] synonym: "muscle of heart of atrium of heart" EXACT [OBOL:automatic] synonym: "muscle of heart of cardiac atrium" EXACT [OBOL:automatic] synonym: "muscle of heart of heart atrium" EXACT [OBOL:automatic] synonym: "myocardium of Cardiac atria" EXACT [OBOL:automatic] synonym: "myocardium of atrium of heart" EXACT [OBOL:automatic] synonym: "myocardium of cardiac atrium" EXACT [OBOL:automatic] synonym: "myocardium of heart atrium" EXACT [OBOL:automatic] xref: FMA:83509 ! Myocardium of atrium xref: VHOG:0000602 ! atrium myocardium xref: MA:0000081 ! atrium myocardium xref: TAO:0001374 ! atrial myocardium xref: ZFA:0001374 ! atrial myocardium xref: EFO:0003087 ! atrial myocardium is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0002081 ! cardiac atrium xref: SCTID:191910002 ! Entire myocardium of atrium synonym: "atrium cardiac muscle" RELATED [VHOG:0000602] property_value: homology_notes "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000602", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.481", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001084 name: skin of head def: "A zone of skin that is part of a head [Automatically generated definition]." [OBOL:automatic] comment: todo - distinguish between entire skin of region and arbitrary zone of skin on region synonym: "head skin" EXACT [] synonym: "adult head zone of skin" EXACT [OBOL:automatic] synonym: "head zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of adult head" EXACT [OBOL:automatic] synonym: "zone of skin of head" EXACT [OBOL:automatic] xref: FMA:12166 ! Skin of head xref: MA:0000582 ! head skin xref: FMA:24756 ! Zone of skin of head xref: ncithesaurus:Head_Skin ! Head Skin is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000033 ! head xref: SCTID:181484006 ! Entire skin of head xref: UMLS:C0205029 [Term] id: UBERON:0001085 name: skin of trunk def: "A zone of skin that is part of a trunk [Automatically generated definition]." [OBOL:automatic] comment: todo - distinguish between entire skin of region and arbitrary zone of skin on region synonym: "trunk skin" EXACT [] synonym: "torso zone of skin" EXACT [OBOL:automatic] synonym: "trunk zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of torso" EXACT [OBOL:automatic] synonym: "zone of skin of trunk" EXACT [OBOL:automatic] xref: FMA:12167 ! Skin of trunk xref: MA:0000517 ! trunk skin xref: FMA:23093 ! Zone of skin of trunk is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002100 ! trunk xref: ncithesaurus:Skin_of_the_Trunk ! Skin of the Trunk xref: SCTID:181489001 ! Entire skin of trunk xref: UMLS:C0205031 [Term] id: UBERON:0001087 ! pleural fluid name: pleural fluid def: "Transudate contained in the pleural cavity.[FMA]" [Wikipedia:Pleural_fluid, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:12273 ! Pleural fluid (also: UBERON:0011893 'endoneurial fluid') xref: MA:0002532 ! pleural fluid xref: MAT:0000500 ! pleural fluid xref: BTO:0003080 ! pleural fluid is_a: UBERON:0007794 {source="FMA"} ! serous fluid intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: located_in UBERON:0002402 ! pleural cavity xref: ncithesaurus:Pleural_Fluid ! Pleural Fluid [Term] id: UBERON:0000175 name: pleural effusion def: "Pleural effusion is a bodily fluid that is produced in exess and accumulates in the pleural cavity, the fluid-filled space that surrounds the lungs. Excessive amounts of such fluid can impair breathing by limiting the expansion of the lungs during inhalation." [ENVO:02000033] comment: cede to MPATH? Note the ncit class is under finding. xref: ENVO:02000033 xref: ncithesaurus:Pleural_Effusion xref: OpenCyc:Mx4rLaTGCK2TEduAAAAOpmP6tw ! pleural effusion is_a: UBERON:0001087 ! pleural fluid [Term] id: UBERON:0001088 name: urine def: "Excretion in liquid state processed by the kidney.[FMA]" [Wikipedia:Urine, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: ENVO:00002047 xref: FMA:12274 ! Urine xref: GAID:1189 ! urine xref: MA:0002545 ! urine xref: MAT:0000058 ! urine xref: MIAA:0000058 ! urine xref: OpenCyc:Mx4rvVjGppwpEbGdrcN5Y29ycA xref: ncithesaurus:Urine ! Urine xref: BTO:0001419 ! urine xref: EFO:0001939 ! urine xref: galen:Urine ! urine xref: OpenCyc:Mx4rvVjGppwpEbGdrcN5Y29ycA ! urine xref: MESH:A12.207.927 ! urine is_a: UBERON:0000174 ! excreta xref: UMLS:C0042036 [Term] id: UBERON:0001089 name: sweat def: "Secretion produced by a sweat gland.[FMA]" [Wikipedia:Sweat, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "skin exudate" RELATED [BTO:0001254] xref: BTO:0001254 xref: ENVO:02000025 xref: FMA:12275 ! Sweat xref: GAID:1172 ! sweat xref: MA:0002539 ! sweat xref: OpenCyc:Mx4rvVjJtZwpEbGdrcN5Y29ycA xref: ncithesaurus:Sweat ! Sweat xref: OpenCyc:Mx4rvVjJtZwpEbGdrcN5Y29ycA ! sweat xref: MESH:A12.200.849 ! sweat is_a: UBERON:0000456 ! bodily secretion xref: UMLS:C0038984 [Term] id: UBERON:0007772 name: scrotal sweat synonym: "sweat of scrotum" EXACT [FMA:73266] xref: FMA:73266 ! sweat of scrotum is_a: UBERON:0001089 {source="FMA"} ! sweat intersection_of: UBERON:0001089 ! sweat intersection_of: secreted_by UBERON:0007773 ! scrotal sweat gland def: "A sweat that secreted_by a scrotal sweat gland." [OBOL:automatic] [Term] id: UBERON:0007773 ! scrotal sweat gland name: scrotal sweat gland xref: EMAPA:29743 ! sweat gland intersection_of: UBERON:0001820 ! sweat gland intersection_of: part_of UBERON:0001300 ! scrotum subset: organ_slim def: "A sweat gland that is part of a scrotum." [OBOL:automatic] [Term] id: UBERON:0001090 ! synovial fluid name: synovial fluid def: "Transudate contained in the synovial cavity of joints, and in the cavity of tendon sheaths and bursae.[FMA]" [Wikipedia:Synovial_fluid, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "joint fluid" EXACT [] xref: ENVO:02000039 xref: FMA:12277 ! Synovial fluid xref: GAID:265 ! synovial fluid xref: MA:0002544 ! synovial fluid xref: ZFA:0005154 ! synovial fluid xref: ncithesaurus:Synovial_Fluid ! Synovial Fluid xref: galen:SynovialFluid ! synovial fluid xref: BTO:0001339 ! synovia xref: MESH:A02.835.583.443.800.800 ! synovial fluid is_a: UBERON:0007794 {source="FMA"} ! serous fluid intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: located_in UBERON:0007617 ! synovial cavity of joint xref: TAO:0005154 ! synovial fluid property_value: external_definition "Portion of organism substance that is a clear fluid that occupies the space in synovial joints.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005154", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0039097 [Term] id: UBERON:0007617 ! synovial cavity of joint name: synovial cavity of joint synonym: "articular cavity (synovial joint)" EXACT [FMA:11356] synonym: "cavitas articularis (junctura synovialis)" EXACT [FMA:11356] synonym: "cavity of synovial joint" EXACT [FMA:11356] xref: FMA:11356 ! synovial cavity of joint intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: part_of UBERON:0002217 ! synovial joint def: "An anatomical cavity that surrounded_by a synovial joint." [OBOL:automatic] [Term] id: UBERON:0007618 name: synovial cavity of hip joint xref: FMA:9701 ! synovial cavity of hip joint xref: EMAPA:19021 ! synovial cavity of hip bone intersection_of: UBERON:0007617 ! synovial cavity of joint intersection_of: part_of UBERON:0001486 ! hip joint relationship: part_of UBERON:0001486 {source="FMA"} ! hip joint def: "A synovial cavity of joint that is part of a hip joint." [OBOL:automatic] [Term] id: UBERON:0007842 name: membrane bone def: "Bone element that arises as a result of intramembranous ossification." [GO_REF:0000034, PSPUB:0000170] xref: VSAO:0000023 ! membrane bone is_a: UBERON:0001474 {source="VSAO"} ! bone element relationship: output_of GO:0001957 ! intramembranous ossification xref: EHDAA2:0003085 ! membrane bone xref: XAO:0004014 ! membrane bone xref: ZFA:0001636 ! membrane bone xref: TAO:0001645 ! membrane bone xref: AEO:0000085 ! membrane bone xref: EHDAA2:0003085 ! membrane bone property_value: external_definition "Bone element that arises as a result of intramembranous ossification.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000023", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170"} property_value: external_definition "Intramembranous bone that forms deep in the organism.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001645", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0002514 ! intramembranous bone name: intramembranous bone def: "Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [Wikipedia:Intramembranous_ossification, GO:0001957] synonym: "membrane bone" RELATED [AEO:0000085] xref: ZFA:0001635 ! intramembranous bone intersection_of: UBERON:0001474 ! bone element intersection_of: output_of GO:0001957 ! intramembranous ossification relationship: develops_from UBERON:0003104 ! mesenchyme xref: TAO:0001644 ! intramembranous bone property_value: external_definition "Bone that forms directly within mesenchyme, and does not replace other tissues.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001644", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_comment "[In TAO], This term was made obsolete because it is considered a synonym of membrane bone (VSAO:0000023).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001644", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0008907 name: dermal bone def: "Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]." [VSAO:curator, VSAO:0000130, Wikipedia:Dermal_bone] is_a: UBERON:0007842 {source="VSAO"} ! membrane bone relationship: part_of UBERON:0010364 {source="VSAO"} ! dermal skeleton intersection_of: UBERON:0007842 ! membrane bone intersection_of: part_of UBERON:0010364 ! dermal skeleton comment: Note that other AOs are not yet in sync with this classification xref: VSAO:0000130 ! dermal bone xref: AAO:0010769 ! dermal bone xref: ZFA:0001590 ! dermal bone xref: XAO:0004015 ! dermal bone xref: TAO:0001590 ! dermal bone property_value: external_definition "Intramembranous bone that forms superficially in the organism.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001590", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0002513 ! endochondral bone name: endochondral bone def: "Replacement bone that forms within cartilage." [Wikipedia:Endochondral_ossification, GO:0001958, VSAO:0000145] comment: note that some structures, e.g. in ZFA are both intramembrane and endochondral. Editor notes: placement in this class to be inferred subset: uberon_slim subset: vertebrate_core synonym: "cartilaginous bone" RELATED [BTO:0002157] synonym: "ossified chondrogenic bone" EXACT [VSAO:0000145] xref: ZFA:0001591 ! endochondral bone xref: BTO:0002157 ! endochondral bone xref: EHDAA2:0003083 ! endochondral bone xref: AEO:0000083 ! endochondral bone xref: VSAO:0000145 ! endochondral bone is_a: UBERON:0010363 {source="VSAO"} ! endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: develops_from UBERON:0005863 ! cartilaginous condensation relationship: developmentally_replaces UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0007844 {source="VSAO"} ! cartilage element xref: AAO:0010776 ! endochondral bone xref: XAO:0004018 ! endochondral bone xref: TAO:0001591 ! endochondral bone xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg property_value: external_definition "Replacement bone that forms within cartilage.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000145", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170"} property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000009" xsd:anyURI [Term] id: UBERON:0004756 ! dermal skeletal element name: dermal skeletal element def: "dermis-derived entity that is made of skeletal tissue." [] synonym: "dermal element" EXACT [VSAO:curator] intersection_of: UBERON:0004765 ! skeletal element intersection_of: develops_from UBERON:0002067 ! dermis intersection_of: has_part UBERON:0004755 ! skeletal tissue [Term] id: UBERON:0002542 ! scale name: scale def: "A small rigid plate that grows out of an animal's skin to provide protection. In lepidopteran (butterfly and moth) species, scales are plates on the surface of the insect wing, and provide coloration. Scales are quite common and have evolved multiple times with varying structure and function." [Wikipedia:Scale_(zoology)] comment: Usage notes: currently defined in a very inclusive fashion - may be obsoleted and replaced by more specific classes in future versions. The TAO, VSAO amd ZFA classes by this name are classified as 'dermal scales' subset: grouping_class synonym: "scales" RELATED [] xref: BTO:0005055 ! scale xref: HAO:0000907 ! scale xref: MAT:0000257 ! scale xref: MIAA:0000257 ! scale xref: OpenCyc:Mx4rvVi9M5wpEbGdrcN5Y29ycA xref: EFO:0000960 ! scale xref: OpenCyc:Mx4rvVi9M5wpEbGdrcN5Y29ycA ! scale is_a: UBERON:0003102 ! surface structure [Term] id: UBERON:0007380 name: dermal scale def: "Dermal bone that is thin, flexible, and platelike, and that develops in overlapping skinfolds that cover the body and often the head of fish and the bases of the fins." [TAO:curator, Wikipedia:Scale_(zoology)#Fish_scales] synonym: "fish scale" RELATED [Wikipedia:Scale_(zoology)#Fish_scales] synonym: "scales" EXACT PLURAL [ZFA:0000277] xref: TAO:0000277 ! scale xref: ZFA:0000277 ! scale xref: VSAO:0000048 ! scale is_a: UBERON:0002542 ! scale relationship: part_of UBERON:0002067 ! dermis xref: AAO:0010056 ! dermal scales [Term] id: UBERON:0008201 name: scute def: "A bony external plate or scale, as on the shell of a turtle, the skin of crocodilians, the feet of some birds. Scutes are similar to scales and serve the same function. Unlike the scales of fish and snakes, which are formed from the epidermis, scutes are formed in the lower vascular layer of the skin and the epidermal element is only the top surface. Forming in the living dermis, the scutes produce a horny outer layer, that is superficially similar to that of scales. Scutes will usually not overlap as snake scales (but see the pangolin). The outer keratin layer is shed piecemeal, and not in one continuous layer of skin as seen in snakes or lizards. The dermal base may contain bone and produce dermal armour. Scutes with a bony base are properly called osteoderms. Dermal scutes are also found in the feet of birds and tails of some mammals, and are believed to be the primitive form of dermal armour in reptiles. The term is also used to describe the heavy armour of the armadillo and the extinct glyptodon, and is occasionally used as an alternative to scales in describing snakes or certain fishes, such as sturgeons[WP]." [Wikipedia:Scute] comment: Currently being reviewed by PHENOSCAPE:ad synonym: "scutum" EXACT [Wikipedia:Scute] synonym: "scuta" EXACT PLURAL [Wikipedia:Scute] synonym: "scutae" EXACT PLURAL [Wikipedia:Scute] synonym: "osteoderm" NARROW [Wikipedia:Scute] xref: SCTID:17148007 ! Scute structure is_a: UBERON:0007381 {source="Kardong", quote="it is a fold in the epidermal surface hence it is an epidermal scale"} ! epidermal scale [Term] id: UBERON:0000041 name: dermal denticle def: "Multi-tissue structure composed of enameloid, dentine surrounding a pulp cavity, and bone of attachment anchoring the element into the dermis[VSAO]. small outgrowths which cover the skin of many cartilaginous fish including sharks. They are similar in structure to teeth, and teeth may have evolved from denticle-like structures in primitive fish.[citation needed] The placoid scales in sharks are formed of dentine with dermal papillae located in the core. These scales develop from the dermal layer of the skin, which is in contrast to the epidermal development seen the in the elasmoid scales of tetrapods. The shape of denticle varies from species to species and can be used in identification. Studies have found that the denticles create tiny vortices that reduce drag to make swimming more efficient. Denticles also allow sharks to swim silently compared to other fish that generate considerable noise when they ply the water[WP]." [Wikipedia:Dermal_denticle, VSAO:0000079] comment: TODO check dentin def // Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. subset: uberon_slim synonym: "placoid scale" EXACT [] xref: VSAO:0000079 ! odontode scale is_a: UBERON:0004756 ! dermal skeletal element relationship: has_part UBERON:0001751 ! dentine property_value: external_definition "Multi-tissue structure composed of enameloid, dentine surrounding a pulp cavity, and bone of attachment anchoring the element into the dermis.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000079", date_retrieved="2012-08-14", source="PSPUB:0000170"} synonym: "odontode scale" EXACT [VSAO:0000079] [Term] id: UBERON:0007381 name: epidermal scale def: "A fold in the surface epidermis composed of keratin[Kardong]." [Wikipedia:Reptile_scale, ISBN10:0073040584] is_a: UBERON:0002542 ! scale relationship: part_of UBERON:0001003 ! epidermis [Term] id: UBERON:0012243 name: nuptial pad def: "Raised calluses of cornified epidermis used by the male to hold the female during mating." [ISBN10:0073040584] is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0001003 {source="Kardong"} ! epidermis [Term] id: UBERON:0012443 ! row of scales name: row of scales synonym: "set of scales" RELATED [] is_a: UBERON:0000477 ! anatomical cluster relationship: composed_primarily_of UBERON:0002542 ! scale [Term] id: UBERON:0012444 name: gastropege def: "a single row of large ventral scales in snakes that aid locomotion." [http://en.wikivet.net] synonym: "row of ventral scales" RELATED [] is_a: UBERON:0012443 ! row of scales [Term] id: UBERON:0003913 name: tooth-like structure def: "hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food." [GOC:cjm] comment: see dermal denticle subset: grouping_class synonym: "tooth-like organ" EXACT [GOC:cjm] xref: HAO:0001019 ! tooth is_a: UBERON:0004765 ! skeletal element relationship: has_function_in GO:0071626 ! mastication [Term] id: UBERON:0003912 name: chitinous tooth def: "tooth-like structure composed of chitin." [] intersection_of: UBERON:0003913 ! tooth-like structure intersection_of: composed_primarily_of CHEBI:17029 ! chitin [Term] id: UBERON:0004289 name: radula def: "an anatomical structure found in mollusks and used for feeding. It is a minutely toothed, chitinous ribbon. It is typically used for scraping or cutting food before the food enters the esophagus. The radula is unique to the molluscs, and is found in all classes of mollusks except for the bivalves." [Wikipedia:Radula] comment: The first bona fide radula dates to the Early Cambrian,[3] although trace fossils from the earlier Ediacaran have been suggested to have been made by the radula of the organism Kimberella.[WP] xref: BTO:0001506 ! radula is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of CHEBI:17029 ! chitin [Term] id: UBERON:0004767 name: vomerine tooth def: "A tooth that is on the vomer." [http://www.encyclo.co.uk/define/Vomerine%20teeth] xref: TAO:0001631 ! vomerine tooth xref: AAO:0000635 ! vomerine_teeth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0002396 ! vomer property_value: external_definition "Tooth that is attached to the vomer.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001631", date_retrieved="2012-08-14", source="TAO:wd"} property_value: axiom_lost_from_external_ontology "relationship type change: OBO_REL:part_of vomer (TAO:0000308) CHANGED TO: attaches_to vomer (UBERON:0002396)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001631", date_retrieved="2012-08-14"} [Term] id: UBERON:0011593 name: maxillary tooth def: "Tooth that is attached to a maxilla[TAO,modified]." [TAO:0001627] synonym: "maxillary teeth" EXACT PLURAL [AAO:0000287] intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0002397 ! maxilla relationship: part_of UBERON:0009680 ! set of upper jaw teeth xref: TAO:0001627 ! maxillary tooth xref: AAO:0000287 ! maxillary teeth xref: SCTID:422279005 ! Entire maxillary tooth property_value: external_definition "Tooth that is attached to the maxilla.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001627", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0011594 name: dentary tooth def: "Tooth that is attached to a dentary/mandible[TAO,modified]." [TAO:0001628] comment: Editor notes: Note that we treat dentary tooth and mandibular tooth as equivalent synonym: "mandibular teeth" RELATED PLURAL [AAO:0000641] synonym: "mandibular tooth" RELATED [] synonym: "tooth of dentary" RELATED [] intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0004742 ! dentary relationship: part_of UBERON:0009679 ! set of lower jaw teeth xref: TAO:0001628 ! dentary tooth xref: AAO:0000125 ! dentary tooth xref: AAO:0000641 ! mandibular teeth xref: SCTID:245547003 ! Entire mandibular teeth property_value: external_definition "Tooth that is attached to the dentary.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001628", date_retrieved="2012-08-14", source="TAO:wd"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of dentary tooth row (TAO:0001952)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001628", date_retrieved="2012-08-14"} [Term] id: UBERON:0011603 name: coronoid tooth def: "Tooth that is attached to a coronoid bone." [UBERON:cjm] synonym: "coronoid teeth" EXACT PLURAL [AAO:0000104] intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0011598 ! coronoid bone relationship: part_of UBERON:0009679 ! set of lower jaw teeth xref: AAO:0000104 ! coronoid tooth [Term] id: UBERON:0012070 name: palatal tooth def: "A tooth that is on the roof of the mouth." [http://palaeos.com/vertebrates/therapsida/anteosauria.html] synonym: "palatal teeth" EXACT PLURAL [] intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0012071 ! palate bone relationship: part_of UBERON:0009680 ! set of upper jaw teeth [Term] id: UBERON:0012071 ! palate bone name: palate bone synonym: "palatal bone" EXACT [] def: "Any bone that is part of a palate." [UBERON:cjm] comment: Note this is distinct (but not disjoint) from palatine bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007375 ! roof of mouth relationship: part_of UBERON:0012072 ! palatal part of dermatocranium xref: ncithesaurus:Palate_Bone ! palate bone xref: UMLS:C1518857 [Term] id: UBERON:0012072 ! palatal part of dermatocranium name: palatal part of dermatocranium synonym: "palatal series" RELATED [ISBN10:0073040584] synonym: "dermatocranium, palatal series" RELATED [ISBN10:0073040584] is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0003113 ! dermatocranium relationship: part_of UBERON:0007375 ! roof of mouth [Term] id: UBERON:0012073 name: tooth of palatine bone def: "A tooth that is attached to a palatine bone." [UBERON:cjm] synonym: "palatine tooth" EXACT [] synonym: "palatine teeth" EXACT PLURAL [] intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0001682 ! palatine bone property_value: external_definition "Teeth present in some fishes on the palatine bones, bones that lie inside the upper jaw bones (sometimes maxillaries, sometimes premaxillaries) usually behind the vomerine tooth patch." xsd:string {source="http://www.fishbase.org/glossary/Glossary.php?q=palatine+teeth"} [Term] id: UBERON:0012074 name: bony part of hard palate synonym: "bony palate" EXACT [FMA:59857] synonym: "palatum osseum" EXACT [FMA:TA] intersection_of: UBERON:0000075 ! subdivision of skeletal system intersection_of: subdivision_of UBERON:0003216 ! hard palate relationship: part_of UBERON:0003216 {source="FMA"} ! hard palate relationship: part_of UBERON:0012072 ! palatal part of dermatocranium xref: FMA:59857 ! bony part of hard palate def: "A subdivision of skeletal system that subdivision_of a hard palate." [OBOL:automatic] [Term] id: UBERON:0013068 name: palatine torus def: "A bony protuberance sometimes found on the hard palate at the junction of the intermaxillary suture and the transverse palatine suture." [http://palaeos.com/vertebrates/glossary/glossaryP.html] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001682 ! palatine bone synonym: "crista palatina" EXACT [FMA:59201] synonym: "torus palatinus" EXACT LATIN [http://palaeos.com/vertebrates/glossary/glossaryP.html] xref: FMA:59201 ! palatine torus [Term] id: UBERON:0005046 name: mucosa of hard palate def: "A mucosa that is part of a hard palate [Automatically generated definition]." [OBOL:automatic] synonym: "hard palate mucosa" EXACT [OBOL:accepted] synonym: "hard palate mucous membrane" EXACT [OBOL:automatic] synonym: "mucous membrane of hard palate" EXACT [OBOL:automatic] synonym: "organ mucosa of hard palate" EXACT [OBOL:automatic] xref: FMA:59783 ! Mucosa of hard palate intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0003216 ! part_of hard palate xref: SCTID:245841005 ! Mucosa of hard palate [Term] id: UBERON:0001091 name: calcareous tooth def: "Organ with a cavity which consist of dentine surrounded by enamel. Examples: incisor, molar." [Wikipedia:Tooth_(animal), Wikipedia:Tooth, FMA:12516] comment: Editors note: we place ZFA ctb 5 tooth here for now. Consider changing name from calcaeous tooth. Note that sea cucumbers develop calcareous tooth-like structures subset: uberon_slim subset: vertebrate_core synonym: "tooth" EXACT [] synonym: "dentine containing tooth" EXACT [] synonym: "vertebrate tooth" EXACT [] xref: BTO:0000397 xref: EFO:0000839 ! tooth xref: FMA:12516 ! Tooth xref: GAID:1260 ! tooth xref: VHOG:0000127 ! tooth xref: MA:0000348 ! tooth xref: MAT:0000041 ! tooth xref: MIAA:0000041 ! tooth xref: OpenCyc:Mx4rvVjUEZwpEbGdrcN5Y29ycA xref: TAO:0001625 ! tooth xref: XAO:0000431 ! tooth xref: ZFA:0000694 ! ceratobranchial 5 tooth xref: ncithesaurus:Tooth ! Tooth xref: OpenCyc:Mx4rvVjUEZwpEbGdrcN5Y29ycA ! tooth xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/14/Teeth_by_David_Shankbone.jpg/200px-Teeth_by_David_Shankbone.jpg xref: MESH:A14.254.860 ! tooth xref: EV:0100063 ! tooth xref: AEO:0000220 xref: EHDAA2:0004605 ! tooth xref: VHOG:0001733 ! tooth xref: SCTID:302214001 ! Entire tooth is_a: UBERON:0003913 ! tooth-like structure relationship: has_developmental_contribution_from UBERON:0005176 {source="ZFA-modified"} ! tooth enamel organ relationship: has_developmental_contribution_from UBERON:0000930 {source="XAO-modified"} ! stomodeum relationship: has_part UBERON:0001751 ! dentine relationship: has_part UBERON:0001752 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! enamel relationship: never_in_taxon NCBITaxon:8782 ! Aves relationship: part_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! jaw region relationship: in_lateral_side_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! jaw region relationship: develops_from UBERON:0005087 {evidence="definitional"} ! tooth placode property_value: homology_notes "The ancestor of recent vertebrate teeth was a tooth-like structure on the outer body surface of jawless fishes.[well established][VHOG]" xsd:string {external_class="VHOG:0001733", ontology="VHOG", source="PMID:19266065 Koussoulakou DS\, Margaritis LH\, Koussoulakos SL\, A curriculum vitae of teeth: evolution\, generation\, regeneration. International Journal of Biological Sciences (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "dental" xsd:string xref: UMLS:C0040426 [Term] id: UBERON:0003856 name: odontogenic mesenchyme def: "Mesenchyme that gives rise to an odontogenic papilla." [UBERON:cjm] comment: Editor notes: we follow ZFA in introducing an additional distinction between the dental papilla and the (uncondensed) mesenchyme. Note that in some species such as zebrafish teeth are not part of the mouth, and sharks have dermal denticles which share similar developmental origins with teeth. For now we assume a NC origin for all and add a taxon restriction to 1st arch mesenchyme subset: vertebrate_core synonym: "tooth mesenchyme" EXACT [OBOL:automatic] synonym: "dental organ mesenchyme" EXACT [OBOL:automatic] synonym: "enamel organ mesenchyme" EXACT [OBOL:automatic] synonym: "tooth enamel organ mesenchyme" EXACT [OBOL:automatic] synonym: "dental mesenchyme" EXACT [ZFA:0005139] xref: VHOG_RETIRED:0001444 xref: ZFA:0005139 ! dental mesenchyme is_a: UBERON:0005253 {source="ZFA"} ! head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005176 ! tooth enamel organ relationship: part_of UBERON:0005176 {source="ZFA"} ! tooth enamel organ relationship: develops_from UBERON:0010259 {source="JB", gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! 1st arch mesenchyme from neural crest relationship: develops_from UBERON:0007213 {notes="see comments"} ! mesenchyme derived from head neural crest xref: TAO:0005139 ! dental mesenchyme property_value: external_definition "Mesenchyme enclosed by dental organ.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005139", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0001763 name: odontogenic papilla def: "Tissue of the developing tooth. It is composed of pre-odontoblast and undiffentiated mesnchyme cells and connects to the basal lamina[ZFA]. The dental papilla is a condensation of ectomesenchymal cells called odontoblasts, seen in histologic sections of a developing tooth. It lies below a cellular aggregation known as the enamel organ. The dental papilla appears after 8-10 weeks intra uteral life. The dental papilla gives rise to the dentin and pulp of a tooth. The enamel organ, dental papilla, and dental follicle together forms one unit, called the tooth germ. This is of importance because all the tissues of a tooth and its supporting structures form from these distinct cellular aggregations." [Wikipedia:Dental_papilla, ZFA:0005140] subset: uberon_slim subset: vertebrate_core synonym: "pharyngeal tooth mesenchyme" NARROW SENSU [ZFA:0005140] synonym: "tooth mesenchyme" RELATED [ZFA:0005140] synonym: "dentinal papilla" RELATED [BTO:0001839] synonym: "papilla dentis" RELATED LATIN [Wikipedia:Dental_papilla] synonym: "dermal papilla" RELATED INCONSISTENT [ISBN10:0073040584] synonym: "dental papilla" RELATED [MA:0001598] xref: FMA:57662 ! Dental papilla xref: GAID:1277 ! dental papilla xref: MA:0001598 ! dental papilla xref: TAO:0005140 ! dental papilla xref: ZFA:0005140 ! dental papilla xref: BTO:0001839 ! dental papilla xref: VHOG:0001465 ! dental papilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/22/Gray1011.png/200px-Gray1011.png xref: MESH:A14.254.900.720.250 ! dental papilla xref: VSAO:0000025 ! odontogenic papilla xref: XAO:0004045 ! odontogenic papilla is_a: UBERON:0005856 {source="JB"} ! developing mesenchymal condensation relationship: part_of UBERON:0005176 {source="BTO", notes="suspect"} ! tooth enamel organ relationship: located_in UBERON:0001828 {source="FMA-implied", gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! gingiva relationship: develops_from UBERON:0003856 {source="ZFA"} ! odontogenic mesenchyme relationship: has_part CL:0000060 ! odontoblast xref: http://upload.wikimedia.org/wikipedia/commons/2/22/Gray1011.png property_value: external_definition "Tissue of the developing tooth. It is composed of pre-odontoblast and undiffentiated mesnchyme cells and connects to the basal lamina.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005140", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Cell condensation that is a well-defined population of densely organized mesenchymal cells that aggregates adjacent to an epithelium.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000025", date_retrieved="2012-08-14", source="PSPUB:0000170"} synonym: "odontogenic condensation" EXACT [VSAO:0000025] property_value: homology_notes "Teeth and tooth-like structures, together named odontodes, are repeated organs thought to share a common evolutionary origin. These structures can be found in gnathostomes at different locations along the body: oral teeth in the jaws, teeth and denticles in the oral-pharyngeal cavity, and dermal denticles on elasmobranch skin.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001465", ontology="VHOG", source="DOI:10.1186/1471-2148-11-307 The homology of odontodes in gnathostomes: insights from Dlx gene expression in the dogfish\, Scyliorhinus canicula. BMC Evolutionary Biology (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0008969 ! dental follicle name: dental follicle def: "The dental follicle is a sac containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts, cementoblasts and fibroblasts. They develop into the alveolar bone, the cementum with Sharpey's fibers and the periodontal ligament fibers respectively." [Wikipedia:Dental_follicle] is_a: UBERON:0005087 {source="BTO"} ! tooth placode relationship: part_of UBERON:0000165 {source="BTO"} ! mouth relationship: develops_from UBERON:0002342 {source="PMID:19767574"} ! neural crest synonym: "tooth follicle" RELATED [BTO:0000337] xref: SCTID:110975002 ! Follicle of tooth xref: BTO:0000337 ! dental follicle [Term] id: UBERON:0005087 ! tooth placode name: tooth placode def: "An tooth placode is a thickening of the ectoderm that will give rise to the tooth bud[GO]." [GO:0060790] comment: Location notes: In mammals this may be located in the alveolar ridges, but note that some species such as zebrafish have ceratobranchial teeth. Sharks have dermal denticles that share developmental origins. Currently we don't include location information due to this diversity, but in future we may include specific subclasses and/or taxon GCIs. synonym: "dental primordium" EXACT [ZFA:0001153] synonym: "tooth germ" RELATED [ZFA:0001153] synonym: "dental placode" EXACT [OBOL:automatic] synonym: "odontogenic placode" EXACT [OBOL:automatic] xref: ZFA:0001153 ! tooth placode is_a: UBERON:0011814 {source="NBK53175"} ! non-neurogenic ectodermal placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: develops_into UBERON:0001091 ! calcareous tooth relationship: has_developmental_contribution_from UBERON:0004362 {source="Wikipedia:Tooth_development", notes="check for other species"} ! pharyngeal arch 1 xref: TAO:0001153 ! tooth placode xref: BTO:0001511 ! tooth germ property_value: external_definition "Placode that develops into a tooth. The placode is a thickening of the pharyngeal epithelium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001153", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0008281 ! tooth bud name: tooth bud def: "A knoblike tooth primordium developing into an enamel organ surrounded by a dental sac and encasing the odontogenic papilla." [BTO:0001838] is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007499 ! epithelial sac relationship: develops_from UBERON:0005087 ! tooth placode synonym: "tooth germ" RELATED [Wikipedia:Tooth_development] xref: BTO:0001838 ! tooth bud xref: ncithesaurus:Tooth_Bud ! Tooth Bud xref: SCTID:53301001 ! Tooth bud xref: MESH:A14.254.900.720 ! tooth germ xref: UMLS:C0040442 [Term] id: UBERON:0004825 name: dental lamina def: "a band of epithelial tissue seen in histologic sections of a developing tooth. The dental lamina is first evidence of tooth development and begins at the sixth week in utero or three weeks after the rupture of the buccopharyngeal membrane. It is formed when cells of the oral ectoderm proliferate faster than cells of other areas. Best described as an in-growth of oral ectoderm, the dental lamina is frequently distinguished from the vestibular lamina, which develops concurrently. This dividing tissue is surrounded by and, some would argue, stimulated by ectomysenchymal growth. When it is present, the dental lamina connects the developing tooth bud to the epithelium of the oral cavity. Eventually, the dental lamina disintegrates into small clusters of epithelium and is resorbed. In situations when the clusters are not resorbed, (this remanent of the dental lamina is sometimes known as the glands of Serres) eruption cysts are formed over the developing tooth and delay its eruption into the oral cavity. This invagination of ectodermal tissues is the progenitor to the later ameloblasts and enamel while the ectomysenchyme is responsible for the odontogenic papilla and later odontoblasts." [Wikipedia:Dental_lamina] synonym: "embryonic dental lamina" EXACT [] comment: Homology notes: In the epidermis of embryonic birds, there remains a transient thickening that is comparable to the early formation of the dental lamina in the mouse[PMID:10954731]. AO notes: check MA placement, this structure is the developing structure xref: MA:0001597 ! dental lamina xref: EMAPA:18292 ! dental lamina of epithelium of incisor of tooth of lower jaw xref: EMAPA:18295 ! dental lamina of epithelium of molar of tooth of lower jaw xref: EMAPA:18298 ! dental lamina of epithelium of incisor of tooth of upper jaw xref: EMAPA:18301 ! dental lamina of epithelium of molar of tooth of upper jaw is_a: UBERON:0000483 ! epithelium is_a: UBERON:0000957 ! lamina relationship: part_of UBERON:0001091 {source="MA"} ! calcareous tooth xref: SCTID:362862007 ! fetal dental lamina synonym: "lamina dentalis" RELATED LATIN [Wikipedia:Dental_lamina] xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Dentallamina11-17-05.jpg [Term] id: UBERON:0005176 ! tooth enamel organ name: tooth enamel organ def: "." [Wikipedia:Enamel_organ, https://sourceforge.net/tracker/?func=detail&aid=3556489&group_id=76834&atid=994726] comment: Editor notes: some sources treat the dental organ as epithelium - we treat it as the mereological sum of dentail epithelium plus dental papilla (consistent with treatment in many AOs), but this may be revised.Development notes: NOT develeops_from NC[UBERONREF:0000002]. Alternate definitioon: A cellular aggregation seen in histologic sections of a developing tooth. It lies above a condensation of ectomesenchymal cells called the odontogenic papilla. Historically, enamel organ has been the term to describe this structure, but it was attempted unsuccessfully in recent years to change the name to dental organ in order to better represent its multiple functions apart from enamel formation[WP] subset: vertebrate_core synonym: "enamel organ" EXACT [MP:0010747] synonym: "dental organ" EXACT [ZFA:0005138] synonym: "odontogenic organ" RELATED [] xref: MA:0001604 ! tooth enamel organ xref: ZFA:0005138 ! dental organ xref: BTO:0001722 ! enamel organ xref: MESH:A14.254.900.720.265 ! enamel organ is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: part_of UBERON:0001091 {source="MA-abduced"} ! calcareous tooth relationship: develops_from UBERON:0005087 {source="ZFA"} ! tooth placode relationship: never_in_taxon NCBITaxon:8782 ! Aves xref: SCTID:362863002 ! Entire enamel organ xref: TAO:0005138 ! dental organ synonym: "organum enameleum" RELATED LATIN [Wikipedia:Enamel_organ] property_value: external_definition "A structure that is involved in tooth formation. A bell shape two layer epithelial structure that descends toward the ceratobranchial 5 bone, enclosing the dental mesenchyme. At later times in tooth development the cells at the apex of the bell may be involved in enameloid formation. This structure remains at the base of the erupted tooth and is the source of replacement teeth.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005138", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0003843 name: dental epithelium def: "Epithelium that is part of a developing tooth or dental organ." [ZFA:0005134, https://sourceforge.net/tracker/?func=detail&aid=3556489&group_id=76834&atid=994726] comment: Editor notes: see comments for dentail organ. Development notes: In the developing molar dentition of the mouse, tooth inductive po- tential resides in the dental epithelium until embryonic day (E)12.5 (3). Thereafter, tooth inductive potential shifts to neural crest-derived dental mesenchyme, which acquires the ability to direct tooth formation in nonodontogenic tissues (3, 4)[PMID:10954731]. Editor notes: todo - full developmental relationships subset: vertebrate_core synonym: "dental epithelia" EXACT PLURAL [ZFA:0005134] synonym: "dental epithelium" EXACT [ZFA:0005134] synonym: "tooth epithelium" EXACT [] synonym: "odontogenic epithelium" EXACT [] xref: VHOG:0001443 xref: ZFA:0005134 ! dental epithelium xref: XAO:0003203 ! dental epithelium xref: BTO:0001723 ! enamel epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005176 ! tooth enamel organ relationship: part_of UBERON:0005176 {source="BTO"} ! tooth enamel organ relationship: develops_from UBERON:0004362 {notes="epithelium", source="JB"} ! pharyngeal arch 1 xref: AAO:0011027 ! dental epithelium xref: TAO:0005134 ! dental epithelium xref: ncithesaurus:Odontogenic_Epithelial_Remnants ! odontogenic epithelium xref: UMLS:C1709309 [Term] id: UBERON:0006949 ! cervical loop name: cervical loop def: "The cervical loop is the location on an enamel organ in a developing tooth where the outer enamel epithelium and the inner enamel epithelium join. The cervical loop is a histologic term indicating a specific epithelial structure at the apical side of the tooth germ, consisting of loosely aggregated stellate reticulum in the center surrounded by stratum intermedium. These tissues are enveloped by a basal layer of epithelium known on the outside of the tooth as outer enamel epithelium and on the inside as inner enamel epithelium. During root formation the inner layers of epithelium disappear and only the basal layers are left creating Hertwig's Epithelial Root Sheath (HERS). At this point it is usually referred to as HERS instead of the cervical loop to indicate the structural difference[WP]." [Wikipedia:Cervical_loop] is_a: UBERON:0003843 ! dental epithelium relationship: part_of UBERON:0005176 ! tooth enamel organ relationship: continuous_with UBERON:0006951 ! inner dental epithelium relationship: continuous_with UBERON:0006952 ! outer dental epithelium [Term] id: UBERON:0006950 name: stellate reticulum alt_id: UBERON:0007441 def: "The stellate reticulum is a group of cells located in the center of the enamel organ of a developing tooth. These cells are star shaped and synthesize glycosaminoglycans. As glycosamingoglycans are produced, water is drawn in between the cells and stretch them apart. As they are moved further away from one another, the stellate reticulum maintain contact with one another through desmosomes, resulting in their unique appearance. stellate reticulum is lost after the first layer of dentin is laid down. this brings cells in inner enamel epithelium closer to blood vessels at the periphery[WP]." [Wikipedia:Stellate_reticulum] is_a: UBERON:0003843 ! dental epithelium xref: BTO:0003910 ! stellate reticulum relationship: part_of UBERON:0005176 {source="BTO"} ! tooth enamel organ relationship: part_of UBERON:0006949 ! cervical loop relationship: capable_of GO:0006024 ! glycosaminoglycan biosynthetic process xref: ncithesaurus:Stellate_Reticulum ! Stellate Reticulum synonym: "reticulum stellatum" RELATED LATIN [Wikipedia:Stellate_reticulum] xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Cervical-loop.png xref: UMLS:C1514963 [Term] id: UBERON:0006951 name: inner dental epithelium def: "Inner layer of the dental organ, composed of ameloblasts[ZFA]. The inner enamel epithelium, also known as the internal enamel epithelium, is a layer of cells located on the rim nearest the odontogenic papilla of the enamel organ in a developing tooth. This layer is first seen during the bell stage. The location of the enamel organ where the outer and inner enamel epithelium join is called the cervical loop[WP]." [ZFIN:curator, Wikipedia:Inner_enamel_epithelium] synonym: "inner enamel epithelium" EXACT [ZFA:0005136] xref: ZFA:0005136 ! inner dental epithelium xref: BTO:0003463 ! inner dental epithelium is_a: UBERON:0003843 {source="ZFA"} ! dental epithelium relationship: part_of UBERON:0005176 ! tooth enamel organ relationship: has_part CL:0000059 ! ameloblast xref: ncithesaurus:Inner_Enamel_Epithelium ! Inner Enamel Epithelium xref: TAO:0005136 ! inner dental epithelium synonym: "epithelium enameleum internum" RELATED LATIN [Wikipedia:Inner_enamel_epithelium] xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Cervical-loop.png property_value: external_definition "Inner layer of the dental organ, composed of ameloblasts.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005136", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C1512780 [Term] id: UBERON:0006952 name: outer dental epithelium def: "Outer layer of the dental organ[ZFA]. a layer of cuboidal cells located on the periphery of the enamel organ in a developing tooth. This layer is first seen during the bell stage." [ZFIN:curator, Wikipedia:Outer_enamel_epithelium] synonym: "outer enamel epithelium" EXACT [OBOL:automatic] synonym: "external enamel epithelium" EXACT [Wikipedia:Outer_enamel_epithelium] synonym: "external dental epithelium" EXACT [BTO:0003462] xref: ZFA:0005137 ! outer dental epithelium xref: BTO:0003462 ! external dental epithelium is_a: UBERON:0003843 {source="ZFA"} ! dental epithelium relationship: part_of UBERON:0005176 ! tooth enamel organ xref: ncithesaurus:Outer_Enamel_Epithelium ! Outer Enamel Epithelium xref: TAO:0005137 ! outer dental epithelium synonym: "epithelium enameleum externum" RELATED LATIN [Wikipedia:Outer_enamel_epithelium] xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Cervical-loop.png property_value: external_definition "Outer layer of the dental organ.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005137", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "outer enamel epithilium" RELATED [TAO:0005137] xref: UMLS:C1518682 [Term] id: UBERON:0007440 name: stratum intermedium of tooth def: "The stratum intermedium in a developing tooth is a layer of two or three cells between the inner enamel epithelium and the newly forming cells of the stellate reticulum. It first appears during the early bell stage of tooth development, at around the 14th week of intrauterine life (in humans). The stratum intermedium has a notably high alkaline phosphatase activity. This layer, along with the inner enamel epithelium, is responsible for the tooth enamel formation. It is a part of the dental (enamel) organ." [Wikipedia:Stratum_intermedium] is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0005176 {source="BTO"} ! tooth enamel organ synonym: "stratum intermedium" BROAD [BTO:0005009] xref: BTO:0005009 ! stratum intermedium xref: ncithesaurus:Stratum_Intermedium ! Stratum Intermedium xref: UMLS:C1514987 [Term] id: UBERON:0003672 ! dentition name: dentition comment: In FMA this is an anatomical set synonym: "set of teeth" EXACT [FMA:75150] synonym: "teeth" EXACT [FMA:75150] synonym: "teeth set" EXACT [FMA:75150] synonym: "teeth" RELATED [] xref: FMA:75150 ! Dentition xref: GAID:1249 ! dentition xref: ncithesaurus:Dentition ! Dentition xref: OpenCyc:Mx4rvVi65JwpEbGdrcN5Y29ycA ! set of teeth xref: AAO:0000126 ! dentition xref: MESH:A14.254 ! dentition is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: has_part UBERON:0001091 ! tooth relationship: part_of UBERON:0010323 ! cranial skeletal system relationship: part_of UBERON:0000165 {source="FMA"} ! mouth synonym: "dentes" EXACT LATIN [FMA:TA, FMA:75150] xref: SCTID:245543004 ! Dentition property_value: external_definition "Dentition refers to set of teeth, especially with regard to their number, kind, and arrangement, in the mouth.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000126", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0011443 [Term] id: UBERON:0009678 ! tooth row name: tooth row def: "Anatomical cluster consisting of adjacent teeth constituting a row." [ZFIN:curator] synonym: "tooth rows" EXACT PLURAL [ZFA:0001642] synonym: "row of teeth" EXACT [UBERON:cjm] synonym: "dental arcade" EXACT [FMA:59415] is_a: UBERON:0003672 ! dentition xref: ZFA:0001642 ! tooth row xref: TAO:0001667 ! tooth row xref: FMA:59415 ! dental arcade [Term] id: UBERON:0012115 name: dental comb def: "a dental structure found in some mammals, comprising a group of front teeth arranged in a manner that facilitates grooming." [Wikipedia:Toothcomb] comment: Taxon notes: The toothcomb occurs in lemuriform primates (which includes lemurs and lorisoids), treeshrews, colugos, hyraxes, and some African antelopes. The structures evolved independently in different types of mammals through convergent evolution and vary both in dental composition and structure. In most mammals the comb is formed by a group of teeth with fine spaces between them. The toothcombs in most mammals include incisors only, while in lemuriform primates they include incisors and canine teeth that tilt forward at the front of the lower jaw, followed by a canine-shaped first premolar. The toothcombs of colugos and hyraxes take a different form with the individual incisors being serrated, providing multiple tines per tooth synonym: "toothcomb" EXACT [Wikipedia:Toothcomb] synonym: "tooth comb" EXACT [Wikipedia:Toothcomb] is_a: UBERON:0009678 ! tooth row relationship: has_function_in GO:0007625 ! grooming behavior [Term] id: UBERON:0001077 ! transverse process of vertebra name: transverse process of vertebra def: "The transverse or costal processes of a vertebra, two in number, project one at either side from the point where the lamina joins the pedicle, between the superior and inferior articular processes. They serve for the attachment of muscles and ligaments. [WP,unvetted]." [Wikipedia:Transverse_process] subset: uberon_slim synonym: "transverse process" EXACT [] synonym: "processus transversus" EXACT [] synonym: "processus transversus vertebrae" EXACT [] synonym: "vertebra transverse process" EXACT [] xref: FMA:11949 ! Transverse process of vertebra xref: MA:0001456 ! vertebra transverse process xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a1/Processustransversusvertebrae.PNG/200px-Processustransversusvertebrae.PNG is_a: UBERON:0006061 ! process of vertebra xref: SCTID:264238006 ! Entire transverse process of vertebra xref: XAO:0003102 ! transverse process xref: AAO:0000698 ! transverse_process [Term] id: UBERON:0003109 name: parapophysis def: "Endochondral bone that forms from a lateral outgrowth of the basiventral arcualia and connects the rib with the vertebral centrum[TAO]. A lateral or ventrolateral projections of vertebrae to which ribs are attached in Danio rerio. ZFA: They can arise through replacement ossification of a basiventral or form directly in bone. They are separated from the centrum in basal teleosts, e.g., Leptolepis coryphaenoides, Megalops and Elops." [ZFIN:curator] comment: TODO - check subset: uberon_slim synonym: "lateral process of basiventral" RELATED [] xref: AAO:0000708 ! parapophysis xref: TAO:0001362 ! parapophysis xref: ZFA:0001362 ! parapophysis is_a: UBERON:0001077 ! transverse process of vertebra relationship: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0002513 ! endochondral bone property_value: external_definition "Projections on each side of the vertebra from the point where the neural arch lamina joins the pedicel for the articulation with the head of a single-headed rib or the upper head of a double-headed rib. Also called diapophyses. They provide surfaces for the attachment of muscles. In anurans, the term transverse process is used in reference to the processes associated with the presacral and postsacral vertebrae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000698", date_retrieved="2012-06-20", source="AAO:Pugener_2002", source="AAO:Pugener_and_Maglia_2008", source="AAO:Trueb_1973"} property_value: external_definition "Paired processes, which arise near the dorsolateral part of the vertebral centrum, for the attachment of the capitulum of two-headed ribs.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000708", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} property_value: external_definition "Endochondral bone that forms from a lateral outgrowth of the basiventral arcualia and connects the rib with the vertebral centrum.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001362", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from basiventral (TAO:0001361)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001362", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of non-Weberian precaudal vertebra (TAO:0001582)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001362", date_retrieved="2012-08-14"} synonym: "parapophyses" EXACT PLURAL [TAO:0001362] synonym: "transverse apophyses" EXACT PLURAL [TAO:0001362] synonym: "transverse apophysis" EXACT [TAO:0001362] [Term] id: UBERON:0005813 ! tubercle name: tubercle def: "a round nodule, small eminence, or warty outgrowth found on bones, skin, or within the lungs in tuberculosis. They are also found on the leading edge of Humpback Whale's flippers, improving fluid flow over the flipper's surface[WP]." [Wikipedia:Tubercle_(anatomy)] subset: grouping_class subset: upper_level xref: FMA:75429 ! tubercle xref: BTO:0002173 ! tubercle is_a: UBERON:0004529 ! anatomical projection xref: AAO:0010605 ! tubercles [Term] id: UBERON:0006770 name: apophysis xref: FMA:75428 ! apophysis is_a: UBERON:0004530 ! bony projection xref: SCTID:65000005 ! Apophysis [Term] id: UBERON:0005815 name: anterior tubercle of transverse process of cervical vertebra synonym: "anterior costal tubercle of transverse process of cervical vertebra" EXACT [FMA:24126] synonym: "anterior tubercle of cervical vertebra" EXACT [FMA:24126] xref: FMA:24126 ! anterior tubercle of transverse process of cervical vertebra is_a: UBERON:0005813 ! tubercle relationship: part_of UBERON:0002413 ! cervical vertebra synonym: "tuberculum cervicales anterius vertebrae" EXACT LATIN [FMA:TA, FMA:24126] [Term] id: UBERON:0005816 name: posterior tubercle of transverse process of cervical vertebra synonym: "posterior costal tubercle of transverse process of cervical vertebra" EXACT [FMA:24128] synonym: "posterior tubercle of cervical vertebra" EXACT [FMA:24128] xref: FMA:24128 ! posterior tubercle of transverse process of cervical vertebra is_a: UBERON:0005813 ! tubercle relationship: part_of UBERON:0002413 ! cervical vertebra synonym: "tuberculum cervicales posterius vertebrae" EXACT LATIN [FMA:TA, FMA:24128] [Term] id: UBERON:0005810 name: cervical vertebra 1 anterior tubercle comment: TODO - check: anterior vs ventral; arch vs transverse process synonym: "cervical vertebra 1 ventral tubercle" EXACT [MA:0002871] synonym: "atlas ventral tubercle" EXACT [MA:0002871] synonym: "ventral tubercle of atlas" EXACT [MP:0010731] synonym: "anterior tubercle of atlas" EXACT [FMA:23991] synonym: "tubercle of anterior arch of atlas" EXACT [FMA:23991] synonym: "tuberculum anterius (atlas)" EXACT [FMA:23991] xref: MA:0002871 ! cervical vertebra 1 ventral tubercle xref: FMA:23991 ! anterior tubercle of atlas is_a: UBERON:0005813 ! tubercle relationship: part_of UBERON:0005814 ! arch of atlas xref: SCTID:281224005 ! Anterior tubercle of atlas [Term] id: UBERON:0005814 ! arch of atlas name: arch of atlas def: "." [Wikipedia:Arch_of_the_atlas] synonym: "atlas arch" EXACT [FMA:23975] xref: FMA:23975 ! arch of atlas xref: SCTID:272708001 ! Arch of atlas intersection_of: UBERON:0010358 ! vertebral arch intersection_of: part_of UBERON:0001092 ! cervical vertebra 1 [Term] id: UBERON:0003996 name: arcus anterior alt_id: UBERON:0005209 def: "The anterior arch of the atlas forms about one-fifth of the ring of the atlas: its anterior surface is convex, and presents at its center the anterior tubercle for the attachment of the Longus colli muscles; posteriorly it is concave, and marked by a smooth, oval or circular facet (fovea dentis), for articulation with the odontoid process (dens) of the axis[WP]. The arch that connects the lateral masses of the atlas anteriorly and articulates with the anterior articular facet of the dens of the axis[MP]." [MP:0009879, Wikipedia:Anterior_arch_of_atlas] synonym: "cervical vertebra 1 arcus anterior" EXACT [MA:0002954] synonym: "anterior arch of atlas" EXACT [MA:0002954] synonym: "arcus anterior atlantis" EXACT [MA:0002954] xref: MA:0002954 ! cervical vertebra 1 arcus anterior xref: FMA:23976 ! Anterior arch of atlas is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0001092 ! atlas xref: SCTID:181891000 ! Entire anterior arch of atlas synonym: "arcus anterior atlantis" RELATED LATIN [Wikipedia:Anterior_arch_of_atlas] xref: http://upload.wikimedia.org/wikipedia/commons/9/9a/Arcusanterioratlantis.png [Term] id: UBERON:0007800 name: proatlas def: "a small, paired bony element (more rarely, having fused parts) located between the skull and the atlas in tuataras, crocodiles, chameleons, and many fossil reptiles; it is uncommon in turtles and mammals (hedgehog). The proatlas apparently develops from the ossified neural part of the sclerotome. Externally it resembles the neural arch of the vertebra, since it articulates anteriorly with the lateral occipital bone and posteriorly with the anterior articular process of the atlas." [http://encyclopedia2.thefreedictionary.com/Proatlas] comment: Variation notes: sometimes seen in humans as an anomaly. is_a: UBERON:0002413 ! cervical vertebra relationship: anterior_to UBERON:0001092 ! atlas [Term] id: UBERON:0001092 name: cervical vertebra 1 def: "." [Wikipedia:Atlas_(anatomy)] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "atlas (CI)" EXACT [] synonym: "C1 vertebra" EXACT [] synonym: "C1" BROAD [] synonym: "first cervical vertebra" EXACT [] synonym: "atlas" EXACT [] synonym: "atlas vertebra" EXACT [] synonym: "cervical atlas" EXACT [MP:0011576] xref: AAO:0000709 ! atlas xref: EHDAA:10606 ! atlas xref: FMA:12519 ! Atlas xref: GAID:236 ! atlas xref: MA:0001421 ! cervical vertebra 1 xref: ncithesaurus:C1_Vertebra ! C1 Vertebra xref: ZFA:0001167 ! vertebra 1 xref: MESH:A02.835.232.834.151.213 ! atla xref: SCTID:181818007 ! Entire atlas vertebra is_a: UBERON:0002413 ! cervical vertebra relationship: anterior_to UBERON:0001093 ! cervical vertebra 2 property_value: vertebra_number "1" xsd:nonNegativeInteger xref: TAO:0001167 ! vertebra 1 relationship: anteriorly_connected_to UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! occipital bone property_value: external_definition "First postcranial vertebra, which is modified anteriorly to articulate with the skull.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000709", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} property_value: external_definition "Vertebra that is posteriorly adjacent to the neurocranium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001167", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "vertebra 1" EXACT [TAO:0001167] xref: UMLS:C0004170 [Term] id: UBERON:0001093 name: cervical vertebra 2 def: "second cervical vertebra (C2) of the spine." [Wikipedia:Axis_(anatomy)] comment: note: not the same as ZFA term 'axis' subset: uberon_slim subset: vertebrate_core synonym: "C2 vertebra" EXACT [] synonym: "C2" BROAD [] synonym: "axis (CII)" EXACT [] synonym: "axis vertebra" EXACT [] synonym: "second cervical vertebra" EXACT [] synonym: "cervical vertebra 2" EXACT [MA:0001422] synonym: "cervical axis" EXACT [MP:0004608] synonym: "axis" RELATED INCONSISTENT [MA:0001422] synonym: "vertebra 2" EXACT [ZFA:0001168] xref: MA:0001422 ! cervical vertebra 2 xref: EHDAA:10608 ! axis xref: FMA:12520 ! Axis xref: GAID:237 ! axis xref: ZFA:0001168 ! vertebra 2 xref: ncithesaurus:C2_Vertebra ! c2 vertebra xref: OpenCyc:Mx4rv-zaJJwpEbGdrcN5Y29ycA ! second cervical vertebra xref: MESH:A02.835.232.834.151.383 ! axis xref: SCTID:181819004 ! Entire axis vertebra is_a: UBERON:0002413 ! cervical vertebra property_value: vertebra_number "2" xsd:nonNegativeInteger xref: TAO:0001168 ! vertebra 2 relationship: anteriorly_connected_to UBERON:0001092 {source="FMA"} ! cervical vertebra 1 property_value: external_definition "Vertebra that is posteriorly adjacent to vertebra 1.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001168", date_retrieved="2012-08-14", source="TAO:wd"} xref: UMLS:C0004457 [Term] id: UBERON:0001095 name: caudal vertebra def: "bones in the tails or coccyx of mammals. In zebrafish: Vertebra bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae." [Wikipedia:Caudal_vertebra, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "caudal vertebrae" EXACT PLURAL [] synonym: "tail vertebra" RELATED [MA:0000310] xref: MA:0000310 ! caudal vertebra xref: OpenCyc:Mx4rv9IEzZwpEbGdrcN5Y29ycA xref: TAO:0000326 ! caudal vertebra xref: XAO:0003079 ! caudal vertebra xref: ZFA:0000326 ! caudal vertebra xref: EMAPA:18374 ! vertebra of axial skeleton of skeleton of tail of embryo intersection_of: UBERON:0002412 ! vertebra intersection_of: part_of UBERON:0006076 ! caudal region of vertebral column property_value: external_definition "Vertebrae bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000326", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0013503 name: caudal vertebra cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0001095 ! caudal vertebra relationship: part_of UBERON:0006076 ! caudal region of vertebral column relationship: develops_from UBERON:0013504 ! caudal vertebra pre-cartilage condensation [Term] id: UBERON:0013504 name: caudal vertebra pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0001095 ! caudal vertebra relationship: part_of UBERON:0006076 ! caudal region of vertebral column [Term] id: UBERON:0006070 name: coccygeal vertebra def: "A caudal vertebra that is part of a coccyx." [UBERON:cjm] comment: AO notes: we assume the MA class represents a subtype of caudal vertebra in what corresponds to the coccyx in humans synonym: "coccygea" RELATED [MA:0001420] synonym: "caudal vertebra" BROAD SENSU [FMA:12527] synonym: "fused tail vertebra" EXACT [UBERON:cjm] synonym: "coccygeal segment" EXACT [] xref: MA:0001420 ! coccygeal vertebra xref: FMA:12527 ! Coccygeal vertebra xref: ncithesaurus:Coccygeal_Vertebra ! Coccygeal Vertebra xref: OpenCyc:Mx4rv9IEzZwpEbGdrcN5Y29ycA ! coccygeal vertebra xref: galen:CoccygealVertebra is_a: UBERON:0001095 {source="MA"} ! caudal vertebra intersection_of: UBERON:0001095 ! caudal vertebra intersection_of: part_of UBERON:0001350 ! coccyx relationship: develops_from UBERON:0013517 ! coccygeal vertebra cartilaginous condensation xref: SCTID:361774004 ! Entire coccygeal vertebra xref: UMLS:C0223616 [Term] id: UBERON:0013517 name: coccygeal vertebra cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0006070 ! coccygeal vertebra relationship: develops_from UBERON:0013518 ! coccygeal vertebra pre-cartilage condensation xref: EHDAA2:0000260 ! coccygeal vertebral cartilage condensation group synonym: "coccygeal vertebral cartilage condensation group" EXACT [EHDAA2:0000260] [Term] id: UBERON:0013518 name: coccygeal vertebra pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0006070 ! coccygeal vertebra [Term] id: UBERON:0006068 name: bone of tail synonym: "tail bone" EXACT [MA:0000696] xref: MA:0000696 ! tail bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007812 ! post-anal tail def: "A bone that is part of a post-anal tail." [OBOL:automatic] [Term] id: UBERON:0001350 ! coccyx name: coccyx def: "A collection of caudal vertebrae in the coccygeal region - may be fused[cjm]." [Wikipedia:Coccyx, UBERON:cjm] comment: In MA the subclass hierarchy is cocc V is_a caud V is_a tail bone. Taxon notes: In humans: The coccyx, commonly referred to as the tailbone, is the final segment of the human vertebral column. Comprising three to five separate or fused vertebrae (the coccygeal vertebrae) below the sacrum, it is attached to the sacrum by a fibrocartilaginous joint, the sacrococcygeal symphysis, which permits limited movement between the sacrum and the coccyx. The term coccyx comes originally from the Greek language and means 'cuckoo', referring to the curved shape of a cuckoo's beak when viewed from the side. [WP,unvetted]. subset: uberon_slim synonym: "coccygeal vertebrae I-IV" EXACT [FMA:20229] synonym: "tailbone" RELATED SENSU [FMA:20229] synonym: "coccyx [coccygeal vertebrae i-iv]" EXACT [FMA:20229] synonym: "coccygeal skeleton" EXACT [EHDAA2:0000259] xref: AAO:0000731 ! coccyx xref: FMA:20229 ! Coccyx xref: GAID:239 ! coccyx xref: galen:Coccyx xref: OpenCyc:Mx4rv1XqHJwpEbGdrcN5Y29ycA xref: ncithesaurus:Coccyx ! Coccyx xref: OpenCyc:Mx4rv1XqHJwpEbGdrcN5Y29ycA ! tail bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/91/Gray100.png/200px-Gray100.png xref: MESH:A02.835.232.834.229 ! coccyx xref: EHDAA2:0000259 ! coccygeal skeleton is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: part_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001270 {source="FMA"} ! bony pelvis relationship: has_fused_element UBERON:0006070 ! coccygeal vertebra synonym: "coccyx [vertebrae coccygeae i-iv]" EXACT LATIN [FMA:TA, FMA:20229] synonym: "os coccygis" EXACT LATIN [FMA:TA, FMA:20229] xref: SCTID:182028002 ! Entire coccyx subset: organ_slim relationship: anteriorly_connected_to UBERON:0003690 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sacrum synonym: "os coccygis" RELATED LATIN [Wikipedia:Coccyx] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Gray100.png property_value: external_definition "Small, bony element consisting of several fused, rudimentary caudal vertebrae; near metamorphosis the hypochord fuses to the coccyx, thereby forming the urostyle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000731", date_retrieved="2012-06-20", source="AAO:Pugener_2002", source="AAO:Pugener_and_Maglia_2008"} property_value: has_relational_adjective "coccygeal" xsd:string xref: UMLS:C0009194 [Term] id: UBERON:0007801 name: pygostyle def: "Pygostyle refers to a number of the final few caudal vertebrae fused into a single ossification, supporting the tail feathers and musculature. In modern birds, the rectrices attach to these[WP]." [Wikipedia:Pygostyle] is_a: UBERON:0001474 ! bone element relationship: part_of UBERON:0001130 ! vertebral column relationship: only_in_taxon NCBITaxon:8782 {source="Wikipedia"} ! Aves xref: SCTID:416894001 ! Pygostyle subset: organ_slim xref: http://people.eku.edu/ritchisong/birdskeleton.gif [Term] id: UBERON:0007802 name: uropygial gland def: "A large gland at the base of a bird's tail dorsal to the cloaca at the end of the pygostyle that secretes an oil used in preening. It opens through a caudally directed nipple." [BTO:0001420, Wikipedia:Uropygial_gland, http://en.wikivet.net] comment: The gland is found near the base of the tail and is shaped into two symmetric parts. The oil of each part of the gland is secreted through the surface of the skin through a grease nipple-like nub. A bird will typically transfer this oil to its feathers by rubbing its head against the oil and then around the rest of the body. Tailward areas are usually preened utilizing the beak. Not all birds have a uropygial gland. Exceptions include the emu, ostrich, and bustards. These typically find other means to stay clean and dry, such as taking a dust bath synonym: "oil gland" RELATED [BTO:0001420] synonym: "preen gland" RELATED [] synonym: "preen oil gland" RELATED [] xref: BTO:0001420 ! uropygial gland is_a: UBERON:0002365 {source="BTO"} ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: secretes UBERON:0007803 ! preen oil relationship: part_of UBERON:0002415 {source="BTO"} ! tail relationship: only_in_taxon NCBITaxon:8782 {source="Wikipedia"} ! Aves relationship: has_function_in GO:0007625 ! grooming behavior relationship: has_function_in NBO:0000451 ! personal grooming xref: SCTID:48626006 ! Uropygial gland subset: organ_slim [Term] id: UBERON:0011676 ! axial subdivision of organism name: axial subdivision of organism def: "A major subdivision of an organism that divides an organism along its anterio-posterior axis. In vertebrates, this is based on the vertebral column." [UBERON:cjm] is_a: UBERON:0000475 ! organism subdivision subset: upper_level [Term] id: UBERON:0005434 ! cervical region name: cervical region synonym: "cervical region" EXACT [FMA:24219] synonym: "neck subdivision" EXACT [FMA:24219] synonym: "region of neck" EXACT [FMA:24219] synonym: "subdivision of neck" EXACT [FMA:24219] xref: FMA:24219 ! Subdivision of neck is_a: UBERON:0011676 ! axial subdivision of organism relationship: part_of UBERON:0000974 ! neck xref: SCTID:123958008 ! Region of neck [Term] id: UBERON:0002100 name: trunk def: "Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present." [TAO:0001115, Wikipedia:Torso, UBERONREF:0000006] comment: editor note - check AAO subset: uberon_slim subset: vertebrate_core synonym: "thoracolumbar region" EXACT [] synonym: "torso" EXACT [] synonym: "Rumpf" RELATED [BTO:0001493] synonym: "trunk region" EXACT [XAO:0000054] xref: BILA:0000116 xref: FMA:7181 ! Trunk xref: MA:0000004 ! trunk xref: MAT:0000296 ! trunk xref: MIAA:0000296 ! trunk xref: OpenCyc:Mx4rvVkJjpwpEbGdrcN5Y29ycA xref: TAO:0001115 ! trunk xref: XAO:0003025 ! trunk xref: ZFA:0001115 ! trunk xref: ncithesaurus:Trunk ! Trunk xref: BTO:0001493 ! trunk xref: EFO:0000966 ! trunk xref: galen:Trunk ! trunk xref: OpenCyc:Mx4rvVkJjpwpEbGdrcN5Y29ycA ! torso xref: AAO:0010339 ! trunk xref: XAO:0000054 ! trunk region is_a: UBERON:0011676 ! axial subdivision of organism relationship: has_part UBERON:0000915 ! thoracic segment of trunk relationship: has_part UBERON:0000916 ! abdomen relationship: spatially_disjoint_from UBERON:0000026 ! appendage relationship: spatially_disjoint_from UBERON:0000033 ! head disjoint_from: UBERON:0002464 ! nerve trunk xref: SCTID:262225004 ! Entire trunk property_value: external_definition "Organism subdivision that is the part of the body posterior to the head and anterior to the tail.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010339", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Organism subdivision which is the part of the body posterior to the head and anterior to the tail.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001115", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0460005 [Term] id: UBERON:0009569 ! subdivision of trunk name: subdivision of trunk synonym: "region of trunk" EXACT [FMA:25054] synonym: "trunk subdivision" EXACT [FMA:25054] subset: non_informative is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0002100 ! trunk xref: FMA:25054 ! subdivision of trunk xref: SCTID:22943007 ! Trunk structure [Term] id: UBERON:0001137 name: dorsum def: "The dorsal part of an animal, which in vertebrares includes the vertebral column. [cjm]." [Wikipedia:Dorsum_(anatomy), UBERONREF:0000006] comment: Taxon notes: In humans, called the back, a large posterior area of the human body, rising from the top of the buttocks to the back of the neck and the shoulders. It is the surface opposite to the chest, its height being defined by the vertebral column (commonly referred to as the spine or backbone) and its breadth being supported by the ribcage and shoulders. The spinal canal runs through the spine and provides nerves to the rest of the body subset: uberon_slim synonym: "back" EXACT [FMA:14181] synonym: "back of body proper" EXACT [FMA:14181] synonym: "dorsal part of organism" EXACT [] xref: FMA:14181 ! back xref: GAID:30 ! back xref: galen:Back xref: OpenCyc:Mx4rvVkEU5wpEbGdrcN5Y29ycA xref: ncithesaurus:Back ! Back xref: EFO:0001405 ! back xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ee/432px-Gray-back.PNG/200px-432px-Gray-back.PNG xref: BTO:0001713 ! dorsum xref: MESH:A01.176 ! back is_a: UBERON:0000475 ! organism subdivision xref: SCTID:123961009 ! Back region property_value: has_relational_adjective "dorsal" xsd:string xref: UMLS:C0004600 [Term] id: UBERON:0013235 ! ventrum name: ventrum def: "The ventral part of an animal. [cjm]." [UBERONREF:0000006] is_a: UBERON:0000475 ! organism subdivision synonym: "front of body proper" EXACT [FMA:259204] synonym: "front" BROAD [] synonym: "ventral region of organism" EXACT [] synonym: "ventral part of organism" EXACT [] synonym: "ventral region" BROAD [] xref: FMA:259204 ! front of body proper [Term] id: UBERON:0011270 name: dorsal trunk def: "The part of the trunk that is in the dorsum[cjm]. In humans, the subdivision of trunk which is demarcated from the trunk proper by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines, the external surface of the posterior abdominal wall; together with the trunk proper, it constitutes the trunk[FMA]." [FMA:25056, Wikipedia:Human_back, UBERONREF:0000006] synonym: "dorsal part of trunk" EXACT [] synonym: "dorsum of trunk" EXACT [FMA:25056] synonym: "trunk back" EXACT [FMA:25056] synonym: "back of trunk" EXACT [FMA:25056] is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum xref: FMA:25056 ! back of trunk xref: MA:0000020 ! back of trunk [Term] id: UBERON:0013236 name: ventral trunk synonym: "anterolateral part of trunk" EXACT [FMA:25055] synonym: "front of trunk" EXACT [FMA:25055] synonym: "trunk front" EXACT [FMA:25055] synonym: "trunk proper" EXACT [FMA:25055] is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk relationship: part_of UBERON:0013235 ! ventrum xref: FMA:25055 ! trunk proper property_value: external_definition "Subdivision of trunk which is demarcated from the back of trunk by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines, the external surface of the posterior abdominal wall and from the limbs by the inguinal folds; together with the back of trunk, it constitutes the trunk. Examples: There is only one trunk proper[FMA:25055]." xsd:string {source="FMA:25055"} [Term] id: UBERON:0008231 name: dorsal thoracic segment of trunk def: "Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax." [FMA:24217] synonym: "dorsum of thorax" EXACT [FMA:24217] synonym: "posterior part of thorax" EXACT [FMA:24217] synonym: "thoracic back" EXACT [FMA:24217] synonym: "thoracic part of back" EXACT [FMA:24217] synonym: "upper back" EXACT [MA:0000028] xref: FMA:24217 ! back of thorax xref: MA:0000028 ! upper back is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0011270 {source="FMA"} ! dorsal trunk relationship: part_of UBERON:0000915 {source="FMA"} ! thoracic segment of trunk relationship: part_of UBERON:0000915 {source="MA"} ! thorax xref: SCTID:362666008 ! Entire upper back synonym: "back of thorax" RELATED [FMA:24217] [Term] id: UBERON:0005473 name: sacral region comment: Taxn notes: Amphibians - 1 sacral vertebra; Living reptiles & most birds - 2 sacral vertebrae; Most mammals - 3 to 5 sacral vertebrae. TODO - split sacral from sacrococcygeal synonym: "back of pelvis" EXACT [FMA:24228] synonym: "pelvic back" EXACT [FMA:24228] synonym: "sacral part of pelvis" EXACT [FMA:24228] synonym: "posterior part of pelvis" EXACT [FMA:24228] synonym: "rump" NARROW SENSU [Wikipedia:Rump_(animal)] synonym: "croup" NARROW SENSU [Wikipedia:Rump_(animal)] xref: FMA:24228 ! Posterior part of pelvis is_a: UBERON:0011676 ! axial subdivision of organism relationship: part_of UBERON:0002355 ! pelvis synonym: "regio sacralis" EXACT LATIN [FMA:TA, FMA:24228] xref: SCTID:182344001 ! Entire sacral region [Term] id: UBERON:0006071 name: caudal region comment: We follow XAO is distinguishing the tail region from the tail; the tail bud is part of the tail region; the tail starts after the tail bud synonym: "postsacral region" RELATED [AAO:0000082] synonym: "tail region" RELATED [AAO:0000082] xref: XAO:0000087 ! tail region is_a: UBERON:0011676 ! axial subdivision of organism relationship: part_of UBERON:0000154 ! posterior region of body [Term] id: UBERON:0004451 ! trunk or cervical vertebra name: trunk or cervical vertebra def: "A vertebra in the trunk or cervical region. Includes all cervical, thoracic and lumbar vertebrae, but excludes caudal vertebra." [UBERONREF:0000006] comment: In humans, there are 24 presacral vertebrae (7 cervical, 12 thoracic, and 5 lumbar). AO notes: it's not clear if the XAO class belongs here or below xref: MA:0002869 ! presacral vertebra xref: XAO:0003077 ! presacral vertebra is_a: UBERON:0002412 ! vertebra union_of: UBERON:0011677 ! trunk vertebra union_of: UBERON:0002413 ! cervical vertebra synonym: "presacral vertebra" EXACT [MA:0002869] [Term] id: UBERON:0011677 ! trunk vertebra name: trunk vertebra def: "A vertebra in the trunk region. For tetrapods, includes lumbar and thoracic vertebrae. Excludes cervical, caudal, sacral (if present)." [UBERONREF:0000006] synonym: "thoracolumbar vertebra" EXACT [] synonym: "abdominal vertebra" RELATED [TAO:0000263] synonym: "trunk vertebra" RELATED [TAO:0000263] is_a: UBERON:0004451 ! trunk or cervical vertebra intersection_of: UBERON:0002412 ! vertebra intersection_of: part_of UBERON:0009568 ! trunk region of vertebral column xref: TAO:0000263 ! precaudal vertebra xref: ZFA:0000263 ! precaudal vertebra property_value: external_definition "Post-Weberian vertebrae lacking hemal spines (Weitzman, 1962), refers generally to the anterior vertebral region bounding the abdominal cavity. Alternate but not quite synonymous terms are abdominal or trunk vertebrae, which bear parapophyses and ribs. In many actinopterygians dorsal to the posterior abdominal cavity there are transitional vertebrae lacking ribs but also without hemal spines or sometimes even enclosed hemal arches. The primary definition would identify these vertebrae as precaudal. Bird and Mabee, 2003.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000263", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "precaudal vertebra" RELATED [TAO:0000263] synonym: "abdominal vertebrae" RELATED [TAO:0000263] synonym: "precaudal vertebrae" RELATED PLURAL [TAO:0000263] synonym: "trunk vertebrae" RELATED [TAO:0000263] [Term] id: UBERON:0006077 ! subdivision of vertebral column name: subdivision of vertebral column def: "A collection of all skeletal elements in some subdivision of the vertebral column." [UBERON:cjm] subset: non_informative synonym: "vertebral region" RELATED [] synonym: "vertebral subdivision" RELATED [] synonym: "vertebral column subdivision" EXACT [FMA:16201] synonym: "subdivision of vertebral skeleton" EXACT [UBERON:cjm] xref: FMA:16201 ! subdivision of vertebral column intersection_of: UBERON:0000075 ! subdivision of skeletal system intersection_of: subdivision_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001137 {source="FMA"} ! back [Term] id: UBERON:0009568 name: trunk region of vertebral column def: "Subdivision of vertebral column that corresponds to the trunk of the body, containing the trunk/presacral vertebrae." [UBERONREF:0000006] synonym: "trunk region" RELATED [AAO:0000612] synonym: "presacral region" RELATED [AAO:0000612] synonym: "thoracolumbar region" RELATED [AAO:0000612] xref: AAO:0000612 ! trunk region (also: UBERON:0006073 'thoracic region of vertebral column') intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0002100 ! trunk intersection_of: part_of UBERON:0002100 ! trunk xref: ncithesaurus:Thoracolumbar_Region ! thoracolumbar region property_value: external_definition "Region of the vertebral column between the atlas and the sacrum consisting of seven to 285 vertebrae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000612", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} xref: SCTID:281699004 ! Entire presacral region [Term] id: UBERON:0006072 ! cervical region of vertebral column name: cervical region of vertebral column def: "That portion of the spine comprising the cervical vertebrae. The neck area of the spine." [Medical_Dictionary:http://medical-dictionary.thefreedictionary.com/] synonym: "cervical vertebral column" EXACT [FMA:24138] synonym: "cervical spinal column" EXACT [FMA:24138] synonym: "cervical spine" EXACT [FMA:24138] synonym: "cervical skeleton" EXACT [EHDAA2:0000238] xref: EHDAA2:0000238 ! cervical skeleton xref: AAO:0000092 ! cervical region xref: EHDAA:5051 ! cervical region xref: EMAPA:17215 ! cervical region xref: FMA:24138 ! Cervical vertebral column xref: BTO:0004148 ! cervical spine intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0005434 ! cervical region relationship: part_of UBERON:0012477 {source="FMA"} ! dorsal part of neck relationship: part_of UBERON:0002090 ! postcranial axial skeleton xref: ncithesaurus:Cervical_Spine ! Cervical Spine xref: SCTID:260488005 ! Entire cervical spine property_value: external_definition "Anterior region of the vertebral column consisting of one to 19 or 20 vertebrae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000092", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} xref: UMLS:C0728985 [Term] id: UBERON:0006073 ! thoracic region of vertebral column name: thoracic region of vertebral column def: "That part of the spine comprising the thoracic vertebrae." [Medical_Dictionary:http://medical-dictionary.thefreedictionary.com/] synonym: "thoracic vertebral column" EXACT [FMA:9140] synonym: "columna vertebralis thoracicus" EXACT [FMA:9140] synonym: "thoracic spine" EXACT [FMA:9140] synonym: "thoracic skeleton" EXACT [EHDAA2:0002013] xref: EHDAA2:0002013 ! thoracic skeleton xref: EHDAA:5063 ! thoracic region xref: EMAPA:17396 ! thoracic region xref: FMA:9140 ! Thoracic vertebral column xref: BTO:0004150 ! thoracic spine xref: AAO:0000612 ! trunk region (also: UBERON:0009568 'trunk region of vertebral column') intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0008231 {source="FMA"} ! dorsal thoracic segment of trunk relationship: part_of UBERON:0002090 ! postcranial axial skeleton xref: ncithesaurus:Thoracic_Spine ! Thoracic Spine xref: SCTID:243931006 ! Entire thoracic spine property_value: external_definition "Region of the vertebral column between the atlas and the sacrum consisting of seven to 285 vertebrae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000612", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} xref: UMLS:C0581269 [Term] id: UBERON:0006074 ! lumbar region of vertebral column name: lumbar region of vertebral column def: "Subdivision of vertebral column that corresponds to the lumbar subdivision of the body, containing the lumbar vertebrae." [UBERONREF:0000006] synonym: "lumbar spine" EXACT [BTO:0004147] synonym: "lumbar vertebral column" EXACT [FMA:16203] synonym: "lumbar skeleton" EXACT [EHDAA2:0001037] xref: EHDAA2:0001037 ! lumbar skeleton xref: EHDAA:5055 ! lumbar region xref: EMAPA:17393 ! lumbar region xref: GAID:31 ! lumbosacral region xref: FMA:16203 ! Lumbar vertebral column xref: BTO:0004147 ! lumbar spine intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0005462 ! lower back relationship: part_of UBERON:0005462 ! lower back relationship: part_of UBERON:0002090 ! postcranial axial skeleton xref: ncithesaurus:Lumbar_Spine ! Lumbar Spine xref: SCTID:243932004 ! Entire lumbar spine [Term] id: UBERON:0006075 ! sacral region of vertebral column name: sacral region of vertebral column def: "Subdivision of vertebral column that corresponds to the sacral subdivision of the body, containing the sacral vertebrae or sacrum." [UBERONREF:0000006] comment: In adult humans, the sacral skeleton is fused and called the sacrum synonym: "sacrum" NARROW [] synonym: "sacral skeleton" EXACT [EHDAA2:0001772] xref: EHDAA2:0001772 ! sacral skeleton xref: AAO:0000724 ! sacral region xref: GAID:32 ! sacrococcygeal region xref: EHDAA:5059 ! sacral region xref: EMAPA:17676 ! sacral region intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0005473 ! sacral region relationship: part_of UBERON:0005473 ! sacral region relationship: part_of UBERON:0002090 ! postcranial axial skeleton property_value: external_definition "Region of the vertebral column represented by one or two vertebrae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000724", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} [Term] id: UBERON:0011271 name: caudal-sacral region of vertebral column def: "Subdivision of vertebral column that is posterior to the sacral region and anterior to the caudal region." [UBERONREF:0000006] comment: Definition to be reviewed for generality across tetrapods xref: AAO:0000080 ! caudal-sacral region is_a: UBERON:0006077 ! subdivision of vertebral column property_value: external_definition "Region of the vertebral column posterior to the sacrum consisting of two to four vertebrae. The last of these vertebrae is distinguished by the possession of a well-developed haemal arch; it supports the posterior part of the cloaca and marks the posterior limit of the trunk.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000080", date_retrieved="2012-06-20", source="AAO:Duellman_and_Treub_1994"} [Term] id: UBERON:0006076 ! caudal region of vertebral column name: caudal region of vertebral column def: "Subdivision of vertebral column that corresponds to the sacral subdivision of the body, containing the caudal vertebrae." [UBERONREF:0000006] comment: in AAO, this is posterior to the caudal-sacral region synonym: "postsacral region" RELATED [AAO:0000082] synonym: "tail region" RELATED [AAO:0000082] synonym: "caudal region" RELATED [AAO:0000082] synonym: "caudal skeleton" EXACT [UBERONREF:0000006] xref: AAO:0000082 ! caudal region intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0006071 ! caudal region relationship: part_of UBERON:0006071 ! caudal region relationship: part_of UBERON:0002090 ! postcranial axial skeleton property_value: external_definition "Region of the vertebral column posterior to the caudal-sacral region, that may consists of two or three to more than 100 vertebrae. These vertebrae exhibit a gradual reduction in the sizes of their transverse processes and zygapophyses, but these structures are never entirely absent. All caudal vertebrae bear haemal arches.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000082", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} [Term] id: UBERON:0002413 name: cervical vertebra def: "A vertebra immediately inferior to the skull[WP]." [Wikipedia:Cervical_vertebrae] comment: In some species, some parts of the skull may be composed of vertebra-like elements, e.g. the occipital bone in humans is composed of four vertebra-like segments. In many vertebrate species, cervical vertebrae are variable in number; however, almost all mammals have seven (including those with very short necks relative to body size, such as elephants or whales, and those with very long necks, such as giraffes). The few exceptions include the manatee and the sloths, of which the two-toed sloth has six cervical vertebrae and the three-toed sloth has up to nine cervical vertebrae. In many species, though not in mammals, the cervical vertebrae bear ribs. In many other groups, such as lizards and saurischian dinosaurs, the cervical ribs are large; in birds they are small and completely fused to the vertebrae. The transverse processes of mammals are homologous to the cervical ribs of other amniotes. Thoracic vertebrae in all species are defined as those vertebrae which also carry a pair of ribs, and lie caudal to the cervical vertebrae. n humans, cervical vertebrae are the smallest of the true vertebrae, and can be readily distinguished from those of the thoracic or lumbar regions by the presence of a foramen (hole) in each transverse process, through which passes the vertebral artery. subset: uberon_slim synonym: "cervical vertebrae" EXACT PLURAL [] xref: FMA:9915 ! Cervical vertebra xref: GAID:235 ! cervical vertebrae xref: galen:CervicalVertebra xref: MA:0000311 ! cervical vertebra xref: XAO:0003076 ! cervical vertebra xref: ncithesaurus:Cervical_Vertebra ! Cervical Vertebra xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f8/Illu_vertebral_column.jpg/200px-Illu_vertebral_column.jpg xref: EMAPA:17674 ! vertebra of cervical region xref: MESH:A02.835.232.834.151 ! cervical vertebrae is_a: UBERON:0004451 ! trunk or cervical vertebra intersection_of: UBERON:0002412 ! vertebra intersection_of: part_of UBERON:0006072 ! cervical region of vertebral column relationship: part_of UBERON:0000974 ! neck relationship: develops_from UBERON:0013505 ! cervical vertebra cartilaginous condensation xref: SCTID:181820005 ! Entire cervical vertebra synonym: "vertebrae cervicales" RELATED LATIN [Wikipedia:Cervical_vertebrae] xref: http://upload.wikimedia.org/wikipedia/commons/f/f8/Illu_vertebral_column.jpg [Term] id: UBERON:0013505 name: cervical vertebra cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0006072 ! cervical region of vertebral column relationship: develops_from UBERON:0013506 ! cervical vertebra pre-cartilage condensation xref: EHDAA2:0000240 ! cervical vertebral cartilage condensation group synonym: "cervical vertebral cartilage condensation group" EXACT [EHDAA2:0000240] [Term] id: UBERON:0013506 name: cervical vertebra pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0006072 ! cervical region of vertebral column [Term] id: UBERON:0002347 name: thoracic vertebra def: "In humans, the 12 thoracic vertebrae compose the middle segment of the vertebral column, between the cervical vertebrae and the lumbar vertebrae. They are intermediate in size between those of the cervical and lumbar regions; they increase in size as one proceeds down the spine, the upper vertebrae being much smaller than those in the lower part of the region. They are distinguished by the presence of facets on the sides of the bodies for articulation with the heads of the ribs, and facets on the transverse processes of all, except the eleventh and twelfth, for articulation with the tubercles of the ribs. [WP,unvetted]." [Wikipedia:Thoracic_vertebrae] subset: uberon_slim synonym: "dorsal vertebra" EXACT [] synonym: "vertebra thoracica" EXACT [] synonym: "thorax vertebra" EXACT [OBOL:automatic] synonym: "vertebra of thorax" EXACT [OBOL:automatic] xref: FMA:9139 ! Thoracic vertebra xref: GAID:244 ! thoracic vertebrae xref: MA:0000314 ! thoracic vertebra xref: OpenCyc:Mx4rvdZIBpwpEbGdrcN5Y29ycA xref: ncithesaurus:Thoracic_Vertebra ! Thoracic Vertebra xref: OpenCyc:Mx4rvdZIBpwpEbGdrcN5Y29ycA ! dorsal vertebra xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/Gray90.png/200px-Gray90.png xref: EMAPA:18011 ! vertebra of thoracic region xref: MESH:A02.835.232.834.892 ! thoracic vertebrae intersection_of: UBERON:0002412 ! vertebra intersection_of: part_of UBERON:0006073 ! thoracic region of vertebral column relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: develops_from UBERON:0013507 ! thoracic vertebra cartilaginous condensation xref: SCTID:181821009 ! Entire thoracic vertebra xref: UMLS:C0039987 [Term] id: UBERON:0013507 name: thoracic vertebra cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0002347 ! thoracic vertebra relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: develops_from UBERON:0013508 ! thoracic vertebra pre-cartilage condensation xref: EHDAA2:0002014 ! thoracic vertebral cartilage condensation group synonym: "thoracic vertebral cartilage condensation group" EXACT [EHDAA2:0002014] [Term] id: UBERON:0013508 name: thoracic vertebra pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0002347 ! thoracic vertebra relationship: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0002414 name: lumbar vertebra def: "Large vertebra of the movable part of the vertebral column, characterized by the absence of the foramen transversarium within the transverse process, and by the absence of facets on the sides of the body." [Wikipedia:Lumbar_vertebrae] comment: Whereas all rats had six lumbar vertebrae, variable patterns in mice included mostly five vertebrae in DBA/2J, mostly six vertebrae in C57BL/6J, and a mix in B6129PF2/J - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700063/ subset: uberon_slim xref: FMA:9921 ! Lumbar vertebra xref: GAID:240 ! lumbar vertebrae xref: MA:0000312 ! lumbar vertebra xref: OpenCyc:Mx4rvaOek5wpEbGdrcN5Y29ycA xref: ncithesaurus:Lumbar_Vertebra ! Lumbar Vertebra xref: galen:LumbarVertebra ! lumbar vertebra xref: OpenCyc:Mx4rvaOek5wpEbGdrcN5Y29ycA ! lumbar vertebra xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c8/Gray93.png/200px-Gray93.png xref: EMAPA:18007 ! vertebra of lumbar region xref: MESH:A02.835.232.834.519 ! lumbar vertebrae intersection_of: UBERON:0002412 ! vertebra intersection_of: part_of UBERON:0006074 ! lumbar region of vertebral column relationship: develops_from UBERON:0013509 ! lumbar vertebra cartilaginous condensation xref: SCTID:181822002 ! Entire lumbar vertebra xref: UMLS:C0024091 [Term] id: UBERON:0013509 name: lumbar vertebra cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0002414 ! lumbar vertebra relationship: part_of UBERON:0006074 ! lumbar region of vertebral column relationship: develops_from UBERON:0013510 ! lumbar vertebra pre-cartilage condensation xref: EHDAA2:0001038 ! lumbar vertebral cartilage condensation group synonym: "lumbar vertebral cartilage condensation group" EXACT [EHDAA2:0001038] [Term] id: UBERON:0013510 name: lumbar vertebra pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0002414 ! lumbar vertebra relationship: part_of UBERON:0006074 ! lumbar region of vertebral column [Term] id: UBERON:0001094 name: sacral vertebra subset: uberon_slim synonym: "sacral segment" EXACT [] synonym: "segment of sacrum" EXACT [] xref: FMA:12526 ! Sacral vertebra xref: MA:0000313 ! sacral vertebra xref: OpenCyc:Mx4rv-ZsXpwpEbGdrcN5Y29ycA xref: XAO:0003078 ! sacral vertebra xref: ncithesaurus:Sacral_Vertebra ! Sacral Vertebra xref: galen:SacralVertebra ! sacral vertebra xref: OpenCyc:Mx4rv-ZsXpwpEbGdrcN5Y29ycA ! sacral vertebra xref: EMAPA:18336 ! vertebra of sacral region intersection_of: UBERON:0002412 ! vertebra intersection_of: part_of UBERON:0006075 ! sacral region of vertebral column relationship: develops_from UBERON:0010745 ! sacral vertebra cartilage condensation xref: SCTID:361773005 ! Entire sacral vertebra def: "A vertebra that is part of a sacral region of vertebral column." [OBOL:automatic] xref: UMLS:C1261045 [Term] id: UBERON:0010744 name: sacral vertebra pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: part_of UBERON:0006075 {source="EHDAA2"} ! sacral region of vertebral column xref: EHDAA2:0001774 ! sacral vertebral pre-cartilage condensation group synonym: "sacral vertebral pre-cartilage condensation group" EXACT [EHDAA2:0001774] xref: EMAPA:17677 ! vertebral pre-cartilage condensation [Term] id: UBERON:0010745 name: sacral vertebra cartilage condensation synonym: "sacral vertebral cartilage condensation" EXACT [] is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0010744 {source="EHDAA2"} ! sacral vertebral pre-cartilage condensation group relationship: part_of UBERON:0006075 {source="EHDAA2"} ! sacral region of vertebral column xref: EHDAA2:0001773 ! sacral vertebral cartilage condensation group synonym: "sacral vertebral cartilage condensation group" EXACT [EHDAA2:0001773] xref: EMAPA:18009 ! vertebral cartilage condensation [Term] id: UBERON:0001948 name: regional part of spinal cord subset: non_informative synonym: "spinal cord part" RELATED [] xref: NIF_GrossAnatomy:birnlex_1496 ! Regional part of spinal cord intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002240 ! spinal cord xref: SCTID:244437008 ! Region of spinal cord xref: ncithesaurus:Spinal_Cord_Part ! Spinal Cord Part def: "A multi-tissue structure that is part of a spinal cord." [OBOL:automatic] xref: UMLS:C1268166 [Term] id: UBERON:0005844 ! spinal cord segment name: spinal cord segment comment: Editor notes: This is currently used loosely to refer to cervical, lumbar, etc as well as the metamerically repeated segments, which may correspond more closely with the ZFA neuromere term synonym: "spinal neuromere" RELATED [TAO:0001332] synonym: "axial regional part of spinal cord" EXACT [NIF_GrossAnatomy:birnlex_2665] synonym: "axial part of spinal cord" EXACT [NIF_GrossAnatomy:birnlex_2665] synonym: "segment of spinal cord" EXACT [FMA:62420] xref: NIF_GrossAnatomy:birnlex_2665 ! Axial regional part of spinal cord xref: FMA:62420 ! Segment of spinal cord xref: ZFA:0001332 ! spinal neuromere is_a: UBERON:0001948 ! regional part of spinal cord xref: SCTID:278748001 ! Segment of spinal cord xref: TAO:0001332 ! spinal neuromere synonym: "spinal neuromeres" RELATED PLURAL [TAO:0001332] [Term] id: UBERON:0002726 ! cervical spinal cord name: cervical spinal cord synonym: "cervical segments of spinal cord [1-8]" EXACT [FMA:71166] synonym: "cervical spinal cord" EXACT [FMA:71166] synonym: "cervical segment of spinal cord" EXACT [FMA:71166] xref: FMA:71166 ! Cervical segment of spinal cord xref: NIF_GrossAnatomy:birnlex_1499 ! Cervical spinal cord xref: ncithesaurus:Cervical_Spinal_Cord ! Cervical Spinal Cord intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: adjacent_to UBERON:0005434 ! cervical region synonym: "segmenta cervicalia medullae spinalis [1-8" EXACT LATIN [FMA:TA, FMA:71166] xref: SCTID:180960003 ! Entire cervical spinal cord def: "A spinal cord segment that adjacent_to a cervical region." [OBOL:automatic] xref: UMLS:C0581619 [Term] id: UBERON:0003038 ! thoracic spinal cord name: thoracic spinal cord def: "The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]." [Wikipedia:Thoracic_spinal_cord] subset: uberon_slim synonym: "thoracic region of spinal cord" EXACT [FMA:71167] synonym: "thoracic segments of spinal cord [1-12]" EXACT [FMA:71167] synonym: "thoracic spinal cord" EXACT [FMA:71167] synonym: "thoracic segment of spinal cord" EXACT [FMA:71167] xref: FMA:71167 ! Thoracic segment of spinal cord xref: NIF_GrossAnatomy:birnlex_966 ! Thoracic spinal cord xref: ncithesaurus:Thoracic_Spinal_Cord ! Thoracic Spinal Cord xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/68/Gray820.png/200px-Gray820.png intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0008231 ! dorsal thoracic segment of trunk synonym: "segmenta thoracica medullae spinalis [1-12]" EXACT LATIN [FMA:TA, FMA:71167] xref: SCTID:278750009 ! Segment of thoracic spinal cord xref: UMLS:C0581620 [Term] id: UBERON:0002792 ! lumbar spinal cord name: lumbar spinal cord def: "." [Wikipedia:Lumbar_spinal_cord] subset: uberon_slim synonym: "lumbar segments of spinal cord [1-5]" EXACT [FMA:71168] synonym: "lumbar spinal cord" EXACT [FMA:71168] synonym: "lumbar segment of spinal cord" EXACT [FMA:71168] xref: FMA:71168 ! Lumbar segment of spinal cord xref: NIF_GrossAnatomy:birnlex_1704 ! Lumbar spinal cord xref: ncithesaurus:Lumbar_Spinal_Cord ! Lumbar Spinal Cord intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: part_of UBERON:0005462 ! lower back synonym: "segmenta lumbalia medullae spinalis [1-5]" EXACT LATIN [FMA:TA, FMA:71168] xref: SCTID:180962006 ! Entire lumbar spinal cord xref: UMLS:C0581621 [Term] id: UBERON:0005843 ! sacral spinal cord name: sacral spinal cord synonym: "sacral segment of spinal cord" EXACT [FMA:256623] synonym: "sacral segments of spinal cord [1-5]" EXACT [FMA:256623] xref: NIF_GrossAnatomy:birnlex_1275 ! Sacral spinal cord xref: FMA:256623 ! Sacral segment of spinal cord intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: adjacent_to UBERON:0005473 ! sacral region synonym: "segmenta sacralia medullae spinalis [1-5]" EXACT LATIN [FMA:TA, FMA:256623] xref: ncithesaurus:Sacral_Spinal_Cord ! Sacral Spinal Cord xref: SCTID:244438003 ! Entire sacral spinal cord def: "A spinal cord segment that adjacent_to a sacral region." [OBOL:automatic] xref: UMLS:C0581669 [Term] id: UBERON:0005845 ! caudal segment of spinal cord name: caudal segment of spinal cord comment: for spinal cord segments, we treat coccygeal/caudal as synonyms - we only differentiate where bone is concerned synonym: "coccygeal segments of spinal cord [1-3]" EXACT [FMA:256635] synonym: "coccygeal segment of spinal cord" EXACT [FMA:256635] xref: FMA:256635 ! coccygeal segment of spinal cord intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: adjacent_to UBERON:0006071 ! caudal region synonym: "segmenta coccygea medullae spinalis [1-3]" EXACT LATIN [FMA:TA, FMA:256635] xref: SCTID:278753006 ! Segment of coccygeal spinal cord def: "A spinal cord segment that adjacent_to a caudal region." [OBOL:automatic] [Term] id: UBERON:0007714 ! cervical subsegment of spinal cord name: cervical subsegment of spinal cord synonym: "segment part of cervical spinal cord" EXACT [NIF_GrossAnatomy:birnlex_1688] xref: FMA:256653 ! cervical subsegment of spinal cord xref: NIF_GrossAnatomy:birnlex_1688 ! Segment part of cervical spinal cord is_a: UBERON:0005844 {source="FMA", source="NIF"} ! spinal cord segment relationship: part_of UBERON:0002726 ! cervical spinal cord xref: SCTID:278749009 ! Segment of cervical spinal cord [Term] id: UBERON:0007715 ! thoracic subsegment of spinal cord name: thoracic subsegment of spinal cord synonym: "segment part of thoracic spinal cord" EXACT [NIF_GrossAnatomy:birnlex_892] xref: FMA:256655 ! thoracic subsegment of spinal cord xref: NIF_GrossAnatomy:birnlex_892 ! Segment part of thoracic spinal cord is_a: UBERON:0005844 {source="FMA", source="NIF"} ! spinal cord segment relationship: part_of UBERON:0003038 ! thoracic spinal cord [Term] id: UBERON:0007716 ! lumbar subsegment of spinal cord name: lumbar subsegment of spinal cord synonym: "segment part of lumbar spinal cord" EXACT [NIF_GrossAnatomy:birnlex_1652] xref: FMA:256657 ! lumbar subsegment of spinal cord xref: NIF_GrossAnatomy:birnlex_1652 ! Segment part of lumbar spinal cord is_a: UBERON:0005844 {source="FMA", source="NIF"} ! spinal cord segment relationship: part_of UBERON:0002792 ! lumbar spinal cord xref: SCTID:278751008 ! Segment of lumbar spinal cord [Term] id: UBERON:0007717 ! sacral subsegment of spinal cord name: sacral subsegment of spinal cord synonym: "segment part of sacral spinal cord" EXACT [NIF_GrossAnatomy:birnlex_1512] xref: FMA:256659 ! sacral subsegment of spinal cord xref: NIF_GrossAnatomy:birnlex_1512 ! Segment part of sacral spinal cord is_a: UBERON:0005844 {source="FMA", source="NIF"} ! spinal cord segment relationship: part_of UBERON:0005843 ! sacral spinal cord xref: SCTID:278752001 ! Segment of sacral spinal cord [Term] id: UBERON:0001096 name: wall of esophagus def: "An anatomical wall that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "esophageal wall" EXACT [] synonym: "esophagus wall" EXACT [] synonym: "anatomical wall of esophagus" EXACT [OBOL:automatic] synonym: "anatomical wall of gullet" EXACT [OBOL:automatic] synonym: "anatomical wall of oesophagus" EXACT [OBOL:automatic] synonym: "esophagus anatomical wall" EXACT [OBOL:automatic] synonym: "gullet anatomical wall" EXACT [OBOL:automatic] synonym: "gullet wall" EXACT [OBOL:automatic] synonym: "oesophagus anatomical wall" EXACT [OBOL:automatic] synonym: "oesophagus wall" EXACT [OBOL:automatic] synonym: "wall of gullet" EXACT [OBOL:automatic] synonym: "wall of oesophagus" EXACT [OBOL:automatic] xref: FMA:12611 ! Wall of esophagus xref: MA:0002691 ! esophagus wall is_a: UBERON:0000060 ! wall intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0001097 name: axillary lymph node def: "The Axillary lymph nodes are of large size, vary from twenty to thirty in number, and may be arranged in the following groups: brachial lymph nodes (or 'lateral') pectoral axillary lymph nodes (or 'anterior') subscapular axillary lymph nodes (or 'posterior') central lymph nodes apical lymph nodes (or 'medial' or 'subclavicular') [WP,unvetted]." [Wikipedia:Axillary_lymph_node, Wikipedia:Axillary_lymph_nodes] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "axillary node" EXACT [] xref: FMA:12771 ! Axillary lymph node xref: MA:0000735 ! axillary lymph node xref: ncithesaurus:Axillary_Lymph_Node ! Axillary Lymph Node xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/73/Gray607.png/200px-Gray607.png is_a: UBERON:0003968 {source="CL:tm"} ! peripheral lymph node relationship: part_of UBERON:0001467 ! shoulder xref: SCTID:181759007 ! Entire axillary lymph node synonym: "nodi lymphoidei axillares" RELATED LATIN [Wikipedia:Axillary_lymph_nodes] xref: http://upload.wikimedia.org/wikipedia/commons/7/73/Gray607.png xref: UMLS:C0729594 [Term] id: UBERON:0001098 name: incisor tooth def: "Incisors are the first kind of tooth in heterodont mammals. They are located in the premaxilla above and mandible below. [WP,unvetted]." [Wikipedia:Incisor_tooth] comment: Humans normally have eight (8) incisors; Among other animals, some other primates, cats and horses have twelve. Rodents have four, while Foxes have nine. Rabbits and hares (lagomorphs) were once considered rodents, but are distinguished by having eight — one small pair, called 'peg teeth', is located directly behind the most anterior pair. Incisors are used to bite off tough foods, such as red meat subset: uberon_slim synonym: "incisor" EXACT [MA:0000349] xref: MA:0000349 ! incisor xref: GAID:1263 ! incisor xref: EHDAA:8011 ! incisor xref: EHDAA:8047 ! incisor xref: FMA:12823 ! Incisor tooth xref: GAID:1263 ! incisor xref: MA:0000349 ! incisor xref: ncithesaurus:Incisor ! Incisor xref: BTO:0001741 ! incisor xref: OpenCyc:Mx4rwP1ch5wpEbGdrcN5Y29ycA ! incisor xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Gray997.png/200px-Gray997.png xref: MESH:A14.254.860.425 ! incisor is_a: UBERON:0001091 ! tooth relationship: part_of UBERON:0003672 ! dentition xref: SCTID:420856006 ! Entire incisor tooth disjoint_from: UBERON:0003655 ! molar tooth disjoint_from: UBERON:0003674 ! cuspid disjoint_from: UBERON:0007120 ! premolar tooth xref: UMLS:C0021156 [Term] id: UBERON:0001099 name: subcostal vein def: "The subcostal vein is a vein in the human body that runs along the bottom of the twelfth rib. It has the same essential qualities as the posterior intercostal veins, except that it cannot be considered intercostal because it is not between two ribs. Each subcostal vein gives off a posterior (dorsal) branch which has a similar distribution to the posterior ramus of an intercostal artery. [WP,unvetted]." [Wikipedia:Subcostal_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:12845 ! Subcostal vein xref: MA:0002222 ! subcostal vein xref: ncithesaurus:Subcostal_Vein ! Subcostal Vein is_a: UBERON:0001638 ! vein xref: SCTID:25248001 ! Entire subcostal vein synonym: "vena subcostalis" RELATED LATIN [Wikipedia:Subcostal_vein] xref: UMLS:C0226653 [Term] id: UBERON:0004711 ! jugular vein name: jugular vein def: "Any one of the several large veins of the neck that drain blood from the head[BTO]. Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins[GAID]. The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava[WP]." [BTO:0001744, Wikipedia:Jugular_vein] synonym: "vena jugularis" RELATED [BTO:0001744] synonym: "jugular" RELATED [] xref: BTO:0001744 ! jugular vein xref: MA:0002154 ! jugular vein xref: GAID:536 ! jugular vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f8/Gray558.png/200px-Gray558.png xref: EMAPA:18638 ! jugular vein xref: MESH:A07.231.908.498 ! jugular vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0000974 ! neck xref: ncithesaurus:Jugular_Vein ! Jugular Vein xref: SCTID:244403000 ! Entire jugular vein xref: http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray558.png xref: UMLS:C0022427 [Term] id: UBERON:0001104 name: anterior jugular vein def: "The anterior jugular vein begins near the hyoid bone by the confluence of several superficial veins from the submaxillary region. It descends between the median line and the anterior border of the Sternocleidomastoideus, and, at the lower part of the neck, passes beneath that muscle to open into the termination of the external jugular, or, in some instances, into the subclavian vein. It varies considerably in size, bearing usually an inverse proportion to the external jugular; most frequently there are two anterior jugulars, a right and left; but sometimes only one. Its tributaries are some laryngeal veins, and occasionally a small thyroid vein. Just above the sternum the two anterior jugular veins communicate by a transverse trunk, the venous jugular arch, which receive tributaries from the inferior thyroid veins; each also communicates with the internal jugular. There are no valves in this vein. [WP,unvetted]." [Wikipedia:Anterior_jugular_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "anterior external jugular vein" EXACT [] xref: FMA:13318 ! Anterior jugular vein xref: MA:0002155 ! anterior jugular vein xref: ncithesaurus:Anterior_Jugular_Vein ! Anterior Jugular Vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f8/Gray558.png/200px-Gray558.png is_a: UBERON:0004711 ! jugular vein relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein xref: SCTID:65478008 ! Entire anterior jugular vein synonym: "vena jugularis anterior" RELATED LATIN [Wikipedia:Anterior_jugular_vein] xref: http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray558.png xref: UMLS:C0226545 [Term] id: UBERON:0001101 name: external jugular vein def: "The external jugular vein receives the greater part of the blood from the exterior of the cranium and the deep parts of the face, being formed by the junction of the posterior division of the posterior facial with the posterior auricular vein. [WP,unvetted]." [Wikipedia:External_jugular_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "external jugular venous tree" EXACT [] synonym: "external jugular" RELATED [EHDAA2:0000468] synonym: "vena jugularis externa" RELATED LATIN [Wikipedia:External_jugular_vein] xref: FMA:13110 ! External jugular vein xref: galen:ExternalJugularVein xref: MA:0002156 ! external jugular vein xref: ncithesaurus:External_Jugular_Vein ! External Jugular Vein xref: OpenCyc:Mx4rvrm0c5wpEbGdrcN5Y29ycA ! external jugular vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png xref: XAO:0000379 ! external jugular xref: EHDAA2:0000468 ! external jugular xref: EMAPA:17875 ! external jugular vein xref: EHDAA:9887 ! external jugular is_a: UBERON:0004711 ! jugular vein relationship: tributary_of UBERON:0001587 {source="FMA"} ! subclavian vein xref: AAO:0010508 ! external jugular xref: SCTID:181373000 ! Entire external jugular vein xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png property_value: external_definition "Vein which collects blood from the muscles of the head and tongue and the thyroid gland.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010508", date_retrieved="2012-06-20", source="AAO:BJB"} xref: UMLS:C0226543 [Term] id: UBERON:0001586 name: internal jugular vein def: "The two internal jugular veins collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]." [Wikipedia:Internal_jugular_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "internal jugular venous tree" EXACT [] synonym: "internal jugular" EXACT [EHDAA2:0000877] xref: EHDAA:5407 ! internal jugular vein xref: FMA:4724 ! Internal jugular vein xref: galen:InternalJugularVein xref: MA:0002157 ! internal jugular vein xref: ncithesaurus:Internal_Jugular_Vein ! Internal Jugular Vein xref: OpenCyc:Mx4rvqdb95wpEbGdrcN5Y29ycA ! internal jugular vein xref: RETIRED_EHDAA2:0000878 ! internal jugular vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Gray562.png/200px-Gray562.png xref: XAO:0000382 ! internal jugular xref: EHDAA2:0000877 ! internal jugular xref: EMAPA:17620 ! internal jugular vein is_a: UBERON:0004711 ! jugular vein xref: AAO:0010236 ! internal jugular vein xref: SCTID:181372005 ! Entire internal jugular vein synonym: "vena jugularis interna" RELATED LATIN [Wikipedia:Internal_jugular_vein] xref: http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray562.png property_value: external_definition "Vein which receives many veins draining the palate, brain, and the orbital, nasal, and auditory regions.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010236", date_retrieved="2012-06-20", source="AAO:BJB"} xref: UMLS:C0226550 [Term] id: UBERON:0010084 name: future diaphragm is_a: UBERON:0000481 ! multi-tissue structure relationship: located_in UBERON:0002323 ! coelemic cavity lumen intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: develops_into UBERON:0001103 ! diaphragm xref: EHDAA2:0000599 ! future diaphragm def: "A skeletal muscle tissue that develops_into a diaphragm." [OBOL:automatic] [Term] id: UBERON:0001103 name: diaphragm def: "The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]." [GO:0060539, Wikipedia:Thoracid_diaphragm] comment: The existence of some membrane separating the pharynx from the stomach can be traced widely among the chordates. Thus amphioxus possesses an atrium by which water exits the pharynx, which has been argued (and disputed) to be homologous to structures in ascidians and hagfishes.[3] The urochordate epicardium separates digestive organs from the pharynx and heart, but the anus returns to the upper compartment to discharge wastes through an outgoing siphon (Thoracic_diaphragm#Comparative_anatomy_and_evolution) subset: uberon_slim synonym: "thoracic diaphragm" EXACT [] synonym: "diaphragm muscle" EXACT [BTO:0000341] synonym: "midriff" RELATED [BTO:0000341] synonym: "phren" RELATED [BTO:0000341] xref: BTO:0000341 xref: FMA:13295 ! Diaphragm xref: GAID:158 ! diaphragm xref: VHOG:0000713 ! diaphragm xref: MA:0001904 ! diaphragm xref: MAT:0000502 ! diaphragm xref: OpenCyc:Mx4rvVivz5wpEbGdrcN5Y29ycA xref: ncithesaurus:Diaphragm ! Diaphragm xref: EFO:0000937 ! diaphragm xref: EMAPA:17701 ! diaphragm xref: MESH:A02.633.567.900.300 ! diaphragm xref: EV:0100376 ! diaphragm is_a: UBERON:0001134 ! skeletal muscle tissue is_a: UBERON:0002426 ! chest muscle relationship: part_of UBERON:0001004 ! respiratory system relationship: never_in_taxon NCBITaxon:8782 {source="Wikipedia:Thoracic_diaphragm#Comparative_anatomy_and_evolution"} ! Aves xref: SCTID:181614006 ! Entire diaphragm xref: EHDAA2:0003495 ! diaphragm muscle subset: organ_slim relationship: immediate_transformation_of UBERON:0010084 {evidence="definitional"} ! future diaphragm property_value: external_definition "A musculomembranous partition separating the abdominal and thoraic cavities and functioning in respiration. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000713", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/diaphragm", source="http://bgee.unil.ch/"} property_value: homology_notes "The mammals are characterized by a diaphragm, which separates the thoracic portion of the body cavity from the abdominal region and assists in drawing air into the lungs and forcing it out. Modern reptiles lack a muscular diaphragm and it is reasonable to suppose that the diaphragm developed as a new device that made possible a large degree of oxygen intake for active animals. The change may have taken place during the transition from reptile to mammal (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000713", ontology="VHOG", source="ISBN:978-0471384618 Colbert EH\, Evolution of the vertebrates: a history of the backboned animals through time (2001) p.278", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "phrenic" xsd:string xref: UMLS:C0011980 [Term] id: UBERON:0011655 ! interclavicle name: interclavicle def: "Dermal bone of pectoral girdle that is median and ventral in position." [VSAO:0000161] comment: See discussion on pectoral girdles - change relationship to overlaps? Kardong: enlarged oval scale. // Present in therapids and monotremes, reduced in size in marsupials and placentals. is_a: UBERON:0008907 {source="VSAO"} ! dermal bone relationship: part_of UBERON:0007831 {source="VSAO"} ! pectoral girdle skeleton xref: VSAO:0000161 ! interclavicle [Term] id: UBERON:0001105 name: clavicle def: "A paired dermal or endochondral bone that is part of the pectoral girdle. The clavicle may be in contact with the interclavicle or coracoid and forms an attachment site for pectoral musculature. [PHENOSCAPE:ad]." [PHENOSCAPE:ad, Wikipedia:Clavicle] comment: Taxon notes: The clavicle first appears as part of the skeleton in primitive bony fish, where it is associated with the pectoral fin; they also have a bone called the cleithrum. In such fish, the paired clavicles run behind and below the gills on each side, and are joined by a solid symphysis on the fish's underside. They are, however, absent in cartilagenous fish and in the vast majority of living bony fish, including all of the teleosts[ISBN 0-03-910284-X] AO Notes: FMA and MA differ in whether they consider this part of the shoulder. Development notes: In most birds and mammals the clavicles are the only dermal elements in the trunk, and is the only membrane bone associated with the pectoral girdle in these taxa. However, there can be secondary cartilage, or subsequent endochondral ossification, or fusion with endochondral elements. In rodents, the lateral ends of the clavicle are endochondral but the main portion is dermal.[ISBN:978-0-12-319060-4] subset: uberon_slim synonym: "collar bone" EXACT [] synonym: "clavicula" EXACT [VSAO:0005031] synonym: "clavicle bone" EXACT [VSAO:0005031] xref: AAO:0000761 ! clavicle xref: FMA:13321 ! Clavicle xref: GAID:182 ! clavicle xref: galen:Clavicle xref: VHOG:0000849 ! clavicle xref: MA:0001329 ! clavicle xref: OpenCyc:Mx4rvVjijZwpEbGdrcN5Y29ycA xref: ncithesaurus:Clavicle ! Clavicle xref: OpenCyc:Mx4rvVjijZwpEbGdrcN5Y29ycA ! clavicle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/59/Pectoral_girdles-en.svg/200px-Pectoral_girdles-en.svg.png xref: EMAPA:18721 ! clavicle xref: MESH:A02.835.232.087.227 ! clavicle is_a: UBERON:0002495 {source="FMA"} ! long bone is_a: UBERON:0003461 {source="MA"} ! shoulder bone relationship: part_of UBERON:0007831 {source="FMA", source="VSAO"} ! pectoral girdle skeleton relationship: has_developmental_contribution_from UBERON:0010843 {source="ISBN:978-0-12-319060-4", notes="from secondary cartilage of fusion"} ! clavicle cartilaginous condensation relationship: develops_from UBERON:0010905 {source="ISBN:978-0-12-319060-4", editor="mah"} ! clavicle bone primordium relationship: in_lateral_side_of UBERON:0002091 ! appendicular skeleton relationship: connected_to UBERON:0000975 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sternum xref: SCTID:181910004 ! Entire clavicle xref: VSAO:0005031 ! clavicle bone xref: http://upload.wikimedia.org/wikipedia/commons/5/59/Pectoral_girdles-en.svg property_value: external_definition "Slender, paired bones of intramembranous origin that invest the anterior margins of the procoracoids.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000761", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of zonal element (AAO:0000936)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000761", date_retrieved="2012-06-20"} property_value: homology_notes "In early tetrapods, the connecting skull bone, the posttemporal, and adjoining shoulder bones, supracleithrum and postcleithrum (=anocleithrum), are absent, leaving a dermal shoulder girdle composed of the remaining ventral elements: the paired cleithrum and clavicle, and an unpaired midventral interclavicle that joins both halves of the girdle across the midline. (...) Several dermal elements of the shoulder persist in early synapsids. The clavicle and interclavicle are present in therapsids and monotremes, but in marsupials and placentals, the interclavicle is absent, the clavicle often is reduced in size, and the scapula becomes the predominant shoulder element.[well established][VHOG]" xsd:string {external_class="VHOG:0000849", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.330-333 and Figure 9.18", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "clavicular" xsd:string xref: UMLS:C0008913 [Term] id: UBERON:0010843 name: clavicle cartilaginous condensation comment: In most birds and mammals the clavicles are the only dermal elements in the trunk, and is the only membrane bone associated with the pectoral girdle in these taxa. However, there can be secondary cartilage, or subsequent endochondral ossification, or fusion with endochondral elements. In rodents, the lateral ends of the clavicle are endochondral but the main portion is dermal.[ISBN:978-0-12-319060-4] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0001105 ! clavicle relationship: part_of UBERON:0007831 ! pectoral girdle skeleton relationship: develops_from UBERON:0010844 ! clavicle pre-cartilage condensation xref: EMAPA:18342 ! clavicle cartilage condensation def: "A cartilaginous condensation that develops_into a clavicle." [OBOL:automatic] [Term] id: UBERON:0010844 name: clavicle pre-cartilage condensation comment: In most birds and mammals the clavicles are the only dermal elements in the trunk, and is the only membrane bone associated with the pectoral girdle in these taxa. However, there can be secondary cartilage, or subsequent endochondral ossification, or fusion with endochondral elements. In rodents, the lateral ends of the clavicle are endochondral but the main portion is dermal.[ISBN:978-0-12-319060-4] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0001105 ! clavicle relationship: part_of UBERON:0007831 ! pectoral girdle skeleton xref: EMAPA:18026 ! clavicle pre-cartilage condensation def: "A pre-cartilage condensation that develops_into a clavicle." [OBOL:automatic] [Term] id: UBERON:0010905 ! clavicle bone primordium name: clavicle bone primordium comment: lateral part derives from a fish dermal bone while the medial part comes from a spur off the manubrium endochondral bone[JB] synonym: "calvicle primordium" EXACT [] is_a: UBERON:0002514 {source="EHDAA2"} ! intramembranous bone relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme relationship: has_developmental_contribution_from UBERON:0002342 {editor="mah", source="PMC1352163", notes="shown in mouse"} ! neural crest relationship: part_of UBERON:0007831 {source="EHDAA2"} ! pectoral girdle skeleton xref: EHDAA2:0000254 ! clavicle bone primordium [Term] id: UBERON:0008255 ! right clavicle name: right clavicle xref: FMA:13322 ! right clavicle is_a: UBERON:0001105 {source="FMA"} ! clavicle intersection_of: UBERON:0001105 ! clavicle intersection_of: in_right_side_of UBERON:0002091 ! appendicular skeleton def: "A clavicle that is in the right side of a entire appendicular skeleton." [OBOL:automatic] [Term] id: UBERON:0008256 name: left clavicle xref: FMA:13323 ! left clavicle is_a: UBERON:0001105 {source="FMA"} ! clavicle intersection_of: UBERON:0001105 ! clavicle intersection_of: in_left_side_of UBERON:0002091 ! appendicular skeleton def: "A clavicle that is in the left side of a entire appendicular skeleton." [OBOL:automatic] [Term] id: UBERON:0007841 name: furcula def: "Dermal bone that develops from the fusion of the paired clavicle condensations in Archosauria. Serves as both an attachment site for pectoral musculature as well as a mechanical strengthening/ spacing element in the pectoral girdle. [PHENOSCAPE:ad]." [PHENOSCAPE:ad, Wikipedia:Furcula] comment: Comment: Found in both avian and non-avian theropods including, but not limited to: Coelophysoids, Allosauroids, Spinosauridae, Tyrannosauroids, Oviraptorosauria, Troodontidae and Dromaeosauridae. Editor notes: currently assigned to be part of the pectoral girdle, but this may be incorrect if PG is a paired structure. synonym: "wishbone" RELATED [Wikipedia:Furcula] synonym: "fused clavicle" RELATED [] synonym: "furcula bone" EXACT [] is_a: UBERON:0008907 ! dermal bone relationship: part_of UBERON:0007831 ! pectoral girdle skeleton relationship: only_in_taxon NCBITaxon:8492 {source="http://people.eku.edu/ritchisong/342notes5.htm"} ! Archosauria relationship: has_fused_element UBERON:0008255 ! right clavicle relationship: has_fused_element UBERON:0008256 ! left clavicle relationship: has_fused_element UBERON:0011655 ! interclavicle [Term] id: UBERON:0001106 name: cephalic vein def: "In human anatomy, the cephalic vein is a superficial vein of the upper limb. It is also called the antecubital vein. It communicates with the basilic vein via the median cubital vein at the elbow and is located in the superficial fascia along the anterolateral surface of the biceps brachii muscle. Superiorly the cephalic vein passes between the deltoid and pectoralis major muscles and through the deltopectoral triangle, where it empties into the axillary vein. It is often visible through the skin, and its location in the deltopectoral groove is fairly consistent, making this site a good candidate for cannulation. It is often referred to as the 'House-man's Friend' for this reason and is generally a good place for cannulaton when a large bore cannula needs to be sited. [WP,unvetted]." [Wikipedia:Cephalic_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "cephalic vein of forearm" EXACT [] xref: FMA:13324 ! Cephalic vein xref: galen:CephalicVein xref: MA:0002092 ! cephalic vein xref: ncithesaurus:Cephalic_Vein ! Cephalic Vein xref: OpenCyc:Mx4rwTpbQZwpEbGdrcN5Y29ycA ! cephalic vein xref: EMAPA:25075 ! cephalic vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0001460 ! arm relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein relationship: tributary_of UBERON:0000985 {source="FMA/obol"} ! axillary vein synonym: "vena cephalica antebrachii" EXACT LATIN [FMA:TA, FMA:13324] xref: SCTID:181391005 ! Entire cephalic vein synonym: "vena cephalica" RELATED LATIN [Wikipedia:Cephalic_vein] xref: http://upload.wikimedia.org/wikipedia/commons/b/ba/Gray574.png xref: UMLS:C0226802 [Term] id: UBERON:0008523 name: infrahyoid muscle def: "The infrahyoid muscles are a group of four pairs of muscles in the anterior part of the neck. (The term infrahyoid refers to the region below to the hyoid bone in the neck. ) Collectively, they are referred to as the strap muscles, because the muscles are long and flat much like a strap." [Wikipedia:Infrahyoid_muscles] synonym: "infrahyoid" RELATED [Wikipedia:Infrahyoid_muscles] synonym: "infrahyoid muscle" RELATED [Wikipedia:Infrahyoid_muscles] synonym: "infrahyoidala" RELATED [Wikipedia:Infrahyoid_muscles] synonym: "strap muscle" RELATED [Wikipedia:Infrahyoid_muscles] synonym: "strap muscles" RELATED [Wikipedia:Infrahyoid_muscles] is_a: UBERON:0005493 ! hyoid muscle xref: FMA:13338 ! infrahyoid muscle xref: SCTID:244829008 ! Entire infrahyoid muscle relationship: innervated_by UBERON:0005430 {source="dbpedia"} ! ansa cervicalis synonym: "musculi infrahyoidei" RELATED LATIN [Wikipedia:Infrahyoid_muscles] xref: http://upload.wikimedia.org/wikipedia/commons/4/48/Infrahyoid_muscles.png [Term] id: UBERON:0001107 name: sternohyoid muscle def: "The sternohyoid muscle is a thin, narrow muscle attaching the hyoid bone to the sternum, one of the paired strap muscles of the infrahyoid muscles serving to depress the hyoid bone. It is innervated by the ansa cervicalis. The muscle arises from the posterior border of the medial end of the clavicle, the posterior sternoclavicular ligament, and the upper and posterior part of the manubrium sterni. Passing upward and medially, it is inserted by short tendinous fibers into the lower border of the body of the hyoid bone. [WP,unvetted]." [Wikipedia:Sternohyoid_muscle] comment: AO notes: Note that as defined here, this structure attaches to the sternum, which is a tetrapod structure. TAO has class 'sternohyoid' as part of mandibular muscle, but no sternum, so excluded here. The TAO/ZFA class has no definition, but the dictionary of icthyology states: "a large muscle originating on the ventral spine of the postcleithrum and inserting on the sides of the urohyal. It functions in rapid opening of the jaw and expanding the buccal cavity" - a generic way of grouping these is via a hyoid - girdle connection synonym: "sternohyoidei" RELATED PLURAL [Wikipedia:Sternohyoid_muscle] synonym: "sternohyoideus" EXACT [Wikipedia:Sternohyoid_muscle] synonym: "sternohyoid" EXACT [Wikipedia:Sternohyoid_muscle] synonym: "sternohyoideus muscle" EXACT [Wikipedia:Sternohyoid_muscle] subset: uberon_slim subset: vertebrate_core xref: FMA:13341 ! Sternohyoid xref: MA:0002383 ! sternohyoid xref: ncithesaurus:Sternohyoid ! Sternohyoid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/67/Sternohyoid_muscle.PNG/200px-Sternohyoid_muscle.PNG xref: EMAPA:19271 ! sternohyoid xref: SCTID:244830003 ! Entire sternohyoid muscle is_a: UBERON:0008523 {source="FMA"} ! infrahyoid muscle relationship: has_muscle_insertion UBERON:0001685 {source="dbpedia"} ! hyoid bone relationship: innervated_by UBERON:0005430 {source="dbpedia"} ! ansa cervicalis relationship: innervated_by UBERON:0001780 {source="dbpedia", notes="inferred"} ! spinal nerve synonym: "musculus sternohyoideus" RELATED LATIN [Wikipedia:Sternohyoid_muscle] relationship: has_muscle_origin UBERON:0002205 {source="dbpedia", notes="manubrium of sternum"} ! manubrium of sternum xref: http://upload.wikimedia.org/wikipedia/commons/6/67/Sternohyoid_muscle.PNG property_value: external_definition "The sternohyoid is a somitic muscle that participates in oral/pharyngeal behaviors and is innervated by the cervical plexus; it attaches to the hyoid appratus and the sternum.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C0224162 [Term] id: UBERON:0001108 name: omohyoid muscle def: "The omohyoid muscle is a muscle at the front of the neck that consists of two bellies separated by an intermediate tendon. It belongs to the group of infrahyoid muscles. [WP,unvetted]." [Wikipedia:Omohyoid_muscle] comment: interior and superior belly subset: uberon_slim synonym: "omohyoid" EXACT [] synonym: "omohyoideus" EXACT [Wikipedia:Omohyoid_muscle] synonym: "omohyoideus muscle" EXACT [Wikipedia:Omohyoid_muscle] xref: FMA:13342 ! Omohyoid xref: MA:0002348 ! omohyoid xref: SCTID:244833001 ! Entire omohyoid muscle xref: ncithesaurus:Omohyoid ! Omohyoid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b0/Gray1210.png/200px-Gray1210.png is_a: UBERON:0008523 {source="FMA"} ! infrahyoid muscle relationship: has_muscle_insertion UBERON:0001685 {source="dbpedia"} ! hyoid bone relationship: innervated_by UBERON:0005430 {source="dbpedia"} ! ansa cervicalis relationship: innervated_by UBERON:0001780 {source="dbpedia", notes="inferred"} ! spinal nerve synonym: "musculus omohyoideus" RELATED LATIN [Wikipedia:Omohyoid_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/b/b0/Gray1210.png property_value: external_definition "The omohyoid is a somitic muscle that participates in oral/pharyngeal behaviors and is innervated by the cervical plexus; it attaches to the hyoid appratus and the scapula.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C0224163 [Term] id: UBERON:0001109 name: sternothyroid muscle def: "The Sternothyreoideus (or Sternothyroid muscle) is shorter and wider than the Sternohyoideus, beneath which it is situated. It arises from the posterior surface of the manubrium sterni, below the origin of the Sternohyoideus, and from the edge of the cartilage of the first rib, and sometimes that of the second rib, it is inserted into the oblique line on the lamina of the thyroid cartilage. This muscle is in close contact with its fellow at the lower part of the neck, but diverges somewhat as it ascends; it is occasionally traversed by a transverse or oblique tendinous inscription. [WP,unvetted]." [Wikipedia:Sternothyroid_muscle] subset: uberon_slim synonym: "sternothyroid" EXACT [] synonym: "sterno-thyroideus" RELATED [Wikipedia:Sternothyroid_muscle] synonym: "sternothyreoidei" RELATED PLURAL [Wikipedia:Sternothyroid_muscle] synonym: "sternothyreoideus" RELATED [Wikipedia:Sternothyroid_muscle] synonym: "sternothyroideus" RELATED [Wikipedia:Sternothyroid_muscle] xref: FMA:13343 ! Sternothyroid xref: MA:0002386 ! sternothyroid xref: ncithesaurus:Sternothyroid ! Sternothyroid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/10/Sternothyroideus.png/200px-Sternothyroideus.png xref: EMAPA:19272 ! sternothyroid xref: SCTID:244831004 ! Entire sternothyroid muscle is_a: UBERON:0008523 {source="FMA"} ! infrahyoid muscle relationship: has_muscle_insertion UBERON:0001738 {source="dbpedia"} ! thyroid cartilage relationship: innervated_by UBERON:0005430 {source="dbpedia"} ! ansa cervicalis relationship: innervated_by UBERON:0001780 {source="dbpedia", notes="inferred"} ! spinal nerve relationship: has_muscle_origin UBERON:0002205 {source="dbpedia"} ! manubrium of sternum synonym: "musculus sternothyroideus" RELATED LATIN [Wikipedia:Sternothyroid_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/1/10/Sternothyroideus.png property_value: external_definition "The sternothyroid is a somitic muscle that participates in oral/pharyngeal behaviors and is innervated by the cervical plexus; it attaches to the thyroid cartilage and the sternum.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C0224166 [Term] id: UBERON:0001110 name: thyrohyoid muscle def: "The thyrohyoid muscle is a small, quadrilateral muscle appearing like an upward continuation of the Sternothyreoideus. It belongs to the infrahyoid muscles group. It arises from the oblique line on the lamina of the thyroid cartilage, and is inserted into the lower border of the greater cornu of the hyoid bone. [WP,unvetted]." [Wikipedia:Thyrohyoid_muscle] subset: uberon_slim synonym: "thyreohyoideus" RELATED [Wikipedia:Thyrohyoid_muscle] synonym: "thyreohyoideus muscle" RELATED [Wikipedia:Thyrohyoid_muscle] synonym: "thyrohyoid" EXACT [Wikipedia:Thyrohyoid_muscle] synonym: "thyrohyoideus" RELATED [Wikipedia:Thyrohyoid_muscle] xref: FMA:13344 ! Thyrohyoid xref: MA:0002393 ! thyrohyoid xref: ncithesaurus:Thyrohyoid ! Thyrohyoid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Thyrohyoid_muscle.PNG/200px-Thyrohyoid_muscle.PNG xref: EMAPA:19273 ! thyrohyoid of pretracheal xref: EMAPA:25143 ! thyrohyoid of pre-tracheal muscle xref: SCTID:244832006 ! Entire thyrohyoid muscle is_a: UBERON:0008523 {source="FMA"} ! infrahyoid muscle relationship: has_muscle_insertion UBERON:0001685 {source="dbpedia"} ! hyoid bone synonym: "musculus thyrohyoideus" RELATED LATIN [Wikipedia:Thyrohyoid_muscle] relationship: innervated_by UBERON:0000962 {source="dbpedia", notes="first cervical nerve via hypoglossal nerve"} ! cervical nerve relationship: innervated_by UBERON:0001650 {source="dbpedia", notes="first cervical nerve via hypoglossal nerve"} ! hypoglossal nerve xref: http://upload.wikimedia.org/wikipedia/commons/a/aa/Thyrohyoid_muscle.PNG property_value: external_definition "The thyrohyoid is a somitic muscle that participates in oral/pharyngeal behaviors and is innervated by C1 and Cranial Nerve XII ; it attaches to the thyroid cartilage and the hyoid apparatus.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C0224167 [Term] id: UBERON:0010921 name: thyrohyoid ligament is_a: UBERON:0008845 {source="FMA"} ! nonskeletal ligament xref: FMA:55135 ! thyrohyoid ligament xref: ncithesaurus:Thyrohyoid_Ligament ! thyrohyoid ligament xref: SCTID:279551000 ! Entire thyrohyoid ligament xref: UMLS:C0225534 [Term] id: UBERON:0010925 name: median thyrohyoid ligament def: "The middle thicker part of the thyrohyoid membrane is termed the median thyrohyoid ligament (middle hyothyroid ligament, middle thyrohyoid ligament), its lateral thinner portions are pierced by the superior laryngeal vessels and the internal branch of the superior laryngeal nerve. Its anterior surface is in relation with the Thyreohyoideus, Sternohyoideus, and Omohyoideus, and with the body of the hyoid bone" [Wikipedia:Median_thyrohyoid_ligament] synonym: "middle thyrohyoid ligament" EXACT [FMA:55138] synonym: "ligamentum thyrohyoideum medianum" EXACT [] is_a: UBERON:0010921 {source="FMA"} ! thyrohyoid ligament xref: FMA:55138 ! median thyrohyoid ligament xref: ncithesaurus:Middle_Thyrohyoid_Ligament ! middle thyrohyoid ligament xref: SCTID:279554008 ! Entire middle thyrohyoid ligament xref: UMLS:C0225535 [Term] id: UBERON:0010926 name: lateral thyrohyoid ligament def: "The lateral thyrohyoid ligament (lateral hyothyroid ligament) is a round elastic cord, which forms the posterior border of the hyothyroid membrane and passes between the tip of the superior cornu of the thyroid cartilage and the extremity of the greater cornu of the hyoid bone. The recurrent laryngeal nerve typical lies lateral to this ligament" [Wikipedia:Lateral_thyrohyoid_ligament] synonym: "ligamentum thyrohyoideum laterale" EXACT [] synonym: "ligamentum hyothyreoideum laterale" EXACT [] is_a: UBERON:0010921 {source="FMA"} ! thyrohyoid ligament xref: FMA:55139 ! lateral thyrohyoid ligament xref: ncithesaurus:Lateral_Thyrohyoid_Ligament ! lateral thyrohyoid ligament xref: SCTID:279555009 ! Lateral thyrohyoid ligament xref: UMLS:C0458565 [Term] id: UBERON:0010927 name: thyroepiglotticus muscle def: "fibers of the thyroarytenoid muscle that continue to the margin of the epiglottis; it closes the inlet to the larynx." [Wikipedia:Thyroepiglottic_muscle, http://medical-dictionary.thefreedictionary.com/thyroepiglottic+muscle] comment: AO notes: not a distinct muscle in FMA synonym: "thyroepiglottus" EXACT [] synonym: "thyroepiglottus muscle" EXACT [] synonym: "pars thyroepiglottica (musculus thyroarytenoideus)" EXACT [FMA:46594] synonym: "pars thyroepiglottica musculus thyroarytenoidei" EXACT LATIN [FMA:TA] synonym: "thyro-epiglottic part of thyro-arytenoid" EXACT [FMA:46594] synonym: "thyroepiglottic muscle" EXACT [FMA:46594] synonym: "thyroepiglottic" EXACT [] synonym: "thyroepiglotticus" EXACT [FMA:46594] is_a: UBERON:0001568 {source="ncithesaurus"} ! muscle of larynx relationship: part_of UBERON:0008576 {source="FMA"} ! thyro-arytenoid xref: FMA:46594 ! thyroepiglotticus xref: ncithesaurus:Thyroepiglottic_Muscle ! thyroepiglottic muscle xref: SCTID:244819001 ! Entire thyroepiglottic muscle synonym: "pars thyroepiglottica musculi thyroarytenoidei" RELATED LATIN [Wikipedia:Thyroepiglottic_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Musculusthyreoarytenoideus.png property_value: external_definition "Thexton, see notes from WG2.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C0224182 [Term] id: UBERON:0001111 name: intercostal muscle def: "Intercostal muscles are several groups of muscles that run between the ribs, and help form and move the chest wall. There are three principal layers; the external intercostal muscles, which aid in quiet and forced inhalation. They originate on ribs 1-11 and have their insertion on ribs 2-12. The external intercostals are responsible for the elevation of the ribs, and expanding the transverse dimensions of the thoracic cavity. Located around the ribs the internal intercostal muscles, which aid in forced expiration (quiet expiration is a passive process). They originate on ribs 2-12 and have their insertions on ribs 1-11. The internal intercostals are responsible for the depression of the ribs decreasing the transverse dimensions of the thoracic cavity. the innermost intercostal muscle, the deep layers of the internal intercostal muscles which are separated from them by the neurovascular bundle. Both the external and internal muscles are innervated by the intercostal nerves, and are provided by the intercostal arteries and intercostal veins. Their fibers run in opposite directions. [WP,unvetted]." [Wikipedia:Intercostal_muscle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "intercostales" RELATED [] xref: FMA:13354 ! Intercostal muscle xref: GAID:159 ! intercostal muscle xref: VHOG:0000903 ! intercostal muscle xref: MA:0002324 ! intercostales xref: ncithesaurus:Intercostal_Muscle ! Intercostal Muscle xref: EFO:0001368 ! intercostal muscle xref: OpenCyc:Mx4rwQo8QJwpEbGdrcN5Y29ycA ! intercostal muscle xref: EHDAA2:0000841 ! intercostal muscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Gray411.png/200px-Gray411.png xref: MESH:A02.633.567.900.500 ! intercostal muscle xref: EHDAA:5988 ! intercostal xref: BTO:0005281 ! intercostal muscle is_a: UBERON:0002426 {source="FMA"} ! chest muscle relationship: located_in UBERON:0012198 {source="cjm"} ! intercostal space relationship: develops_from UBERON:0010970 {source="EHDAA2"} ! intercostal pre-muscle mass xref: SCTID:181746004 ! Entire intercostal muscle relationship: innervated_by UBERON:0003727 {source="dbpedia"} ! intercostal nerve relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="ribs 2-12"} ! rib relationship: has_muscle_origin UBERON:0002228 {source="dbpedia", notes="ribs 1-11"} ! rib xref: http://upload.wikimedia.org/wikipedia/commons/f/f2/Gray411.png property_value: homology_notes "Inspiration by active expansion of the thorax evolved later, in the ancestor of reptiles, birds, and mammals. This was powered originally by the intercostal muscles (as in lizards or crocodilians) and later (in mammals only) by a muscular diaphragm.[well established][VHOG]" xsd:string {external_class="VHOG:0000903", ontology="VHOG", source="ISBN:978-0262112789 Kent RD\, The MIT Encyclopedia of Communication Disorders (20039 p.56", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0021724 [Term] id: UBERON:0010970 name: intercostal pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0003897 {source="EHDAA2"} ! axial muscle relationship: located_in UBERON:0012198 {source="cjm"} ! intercostal space xref: EHDAA2:0000843 ! intercostal pre-muscle mass [Term] id: UBERON:0001112 name: latissimus dorsi muscle def: "The latissimus dorsi is the larger, flat, dorso-lateral muscle on the trunk, posterior to the arm, and partly covered by the trapezius on its median dorsal region. [WP,unvetted]." [Wikipedia:Latissimus_dorsi_muscle] subset: uberon_slim synonym: "latissimus dorsi" EXACT [] synonym: "musculus latissimus dorsi" EXACT [] xref: EHDAA:8307 ! latissimus dorsi xref: FMA:13357 ! Latissimus dorsi xref: VHOG:0000930 ! latissimus dorsi xref: MA:0002331 ! latissimus dorsi xref: EHDAA2:0000932 ! latissimus dorsi xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Latissimus_dorsi.png/200px-Latissimus_dorsi.png xref: EMAPA:18178 ! latissimus dorsi xref: EFO:0003067 ! latissimus dorsi xref: ncithesaurus:Musculus_Latissimus_Dorsi ! musculus latissimus dorsi is_a: UBERON:0001482 ! muscle of shoulder relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle relationship: develops_from UBERON:0010982 {source="EHDAA2"} ! latissimus dorsi pre-muscle mass relationship: has_muscle_antagonist UBERON:0001476 {source="dbpedia"} ! deltoid relationship: has_muscle_antagonist UBERON:0002380 {source="dbpedia"} ! trapezius synonym: "musculus latissimus dorsi" RELATED LATIN [Wikipedia:Latissimus_dorsi_muscle] relationship: has_muscle_insertion UBERON:0000976 {source="dbpedia", notes="floor of intertubercular groove of the humerus"} ! humerus relationship: has_muscle_origin UBERON:0007175 {source="dbpedia", notes="spinous processes of thoracic T7-T12 thoracolumbar fascia iliac crest and inferior 3 or 4 ribs inferior angle of scapula"} ! inferior angle of scapula xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Latissimus_dorsi.png xref: SCTID:181747008 ! Entire latissimus dorsi muscle xref: UMLS:C0224362 [Term] id: UBERON:0010982 name: latissimus dorsi pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle xref: EHDAA2:0000933 ! latissimus dorsi pre-muscle mass [Term] id: UBERON:0001113 name: lobe of liver def: "Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe." [Wikipedia:Liver#Lobes] comment: editor note: some work needs to be done to ensure the child terms of this class have correct isa/partof placement. in MA they are subclasses, in FMA they are parts synonym: "hepatic lobe" EXACT [] synonym: "liver lobe" EXACT [] synonym: "lobus hepatis" EXACT [] xref: FMA:13361 ! Lobe of liver xref: MA:0000360 ! liver lobe xref: ncithesaurus:Liver_Lobe ! Liver Lobe xref: EMAPA:18306 ! lobe of liver is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002107 ! liver xref: SCTID:245378000 ! Lobe of liver xref: UMLS:C0447541 [Term] id: UBERON:0001114 ! right lobe of liver name: right lobe of liver def: "The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]." [Wikipedia:Right_lobe_of_liver] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "lobus hepaticus dexter" EXACT LATIN [] synonym: "liver right lobe" EXACT [] synonym: "right liver lobe" EXACT [ZFA:0005173] synonym: "gall bladder lobe" RELATED SENSU [ZFA:0005173] xref: FMA:13362 ! Right lobe of liver xref: VHOG:0001424 ! liver right lobe xref: MA:0000363 ! liver right lobe xref: ZFA:0005173 ! right liver lobe xref: EHDAA2:0001008 ! liver right lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Gray1087-liver.png/200px-Gray1087-liver.png xref: EMAPA:18311 ! right of lobe of liver xref: EHDAA:4001 ! right lobe of liver is_a: UBERON:0001113 ! lobe of liver xref: ncithesaurus:Right_Lobe_of_the_Liver ! Right Lobe of the Liver xref: SCTID:362182008 ! Entire right lobe of liver xref: TAO:0005173 ! right liver lobe synonym: "lobus hepatis dexter" RELATED LATIN [Wikipedia:Right_lobe_of_liver] xref: http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png property_value: external_definition "Portion of the liver which develops on the fish's right side adjacent to the gall bladder.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005173", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "2nd lobe" RELATED [TAO:0005173] synonym: "second lobe" RELATED [TAO:0005173] xref: UMLS:C0227481 [Term] id: UBERON:0001115 ! left lobe of liver name: left lobe of liver def: "The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]." [Wikipedia:Left_lobe_of_liver] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "lobus hepaticus sinister" EXACT LATIN [] synonym: "left liver lobe" EXACT [] synonym: "liver left lobe" EXACT [] xref: FMA:13363 ! Left lobe of liver xref: VHOG:0001423 ! liver left lobe xref: MA:0000361 ! liver left lobe xref: ZFA:0005172 ! left liver lobe xref: EHDAA2:0001000 ! liver left lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Gray1087-liver.png/200px-Gray1087-liver.png xref: EMAPA:18307 ! left of lobe of liver xref: EHDAA:3995 ! left lobe of liver is_a: UBERON:0001113 ! lobe of liver xref: ncithesaurus:Left_Lobe_of_the_Liver ! Left Lobe of the Liver xref: SCTID:362183003 ! Entire left lobe of liver xref: TAO:0005172 ! left liver lobe synonym: "lobus hepatis sinister" RELATED LATIN [Wikipedia:Left_lobe_of_liver] xref: http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png property_value: external_definition "Portion of the liver which develops on the fish's left side.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005172", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0227486 [Term] id: UBERON:0001116 name: quadrate lobe of liver def: "The quadrate lobe is an area of the liver situated on the under surface of the right lobe, bounded in front by the anterior margin of the liver; behind by the porta hepatis; on the right, by the fossa for the gall-bladder; and on the left, by the fossa for the umbilical vein. It is oblong in shape, its antero-posterior diameter being greater than its transverse. [WP,unvetted]." [Wikipedia:Quadrate_lobe_of_liver] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "liver quadrate lobe" EXACT [] synonym: "lobus quadratus" EXACT [] xref: FMA:13364 ! Quadrate lobe of liver xref: VHOG:0000509 ! liver quadrate lobe xref: MA:0000365 ! liver quadrate lobe xref: ncithesaurus:Lobus_Quadratus ! Lobus Quadratus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Gray1087-liver.png/200px-Gray1087-liver.png xref: EHDAA2:0001012 ! liver right quadrate lobe xref: EMAPA:18318 ! quadrate lobe xref: EHDAA:8082 ! quadrate lobe is_a: UBERON:0001114 ! right lobe of liver xref: SCTID:279929003 ! Entire quadrate lobe of liver synonym: "lobus quadratus" RELATED LATIN [Wikipedia:Quadrate_lobe_of_liver] xref: http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png property_value: external_definition "The portion of the right lobe of the liver between the gall bladder, the porta hepatis, the round ligament and the lower margin of the organ. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000509", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001117 name: caudate lobe of liver def: "The caudate lobe (posterior hepatic segment I, Spigelian lobe) is situated upon the postero-superior surface of the liver on the right lobe of the liver, opposite the tenth and eleventh thoracic vertebrae. It is bounded on the left side by the physiological division of the liver called the ligamentum venosum. It is bounded, below, by the porta; on the right, by the fossa for the inferior vena cava; and, on the left, by the fossa for the ductus venosus. It looks backward, being nearly vertical in position; it is longer from above downward than from side to side, and is somewhat concave in the transverse direction. The caudate process is a small elevation of the hepatic substance extending obliquely and laterally, from the lower extremity of the caudate lobe to the under surface of the right lobe. It is situated behind the porta, and separates the fossa for the gall-bladder from the commencement of the fossa for the inferior vena cava. Budd-Chiari syndrome, caused by occlusion of hepatic venous outflow, can lead to hypertrophy of the caudate lobe due to its own caval anastomosis that allows for continued function of this lobe of the liver. [WP,unvetted]." [Wikipedia:Caudate_lobe_of_liver] comment: Editor/taxon notes: Check left vs right in mouse and human subset: uberon_slim synonym: "hepatovenous segment i" EXACT [] synonym: "liver caudate lobe" EXACT [] synonym: "liver caudate process" RELATED [] synonym: "lobus caudatus" EXACT [] synonym: "posterior hepatic segment i" EXACT [] synonym: "posterior liver" EXACT [] synonym: "posterior part of liver" EXACT [] synonym: "segment i of liver" EXACT [] synonym: "spiegelian lobe" EXACT [] synonym: "spigel lobe" EXACT [] synonym: "lobus caudatus" EXACT [] synonym: "couinaud hepatic segment i" EXACT [FMA:13365] synonym: "pars posterior hepatis" EXACT LATIN [FMA:TA, FMA:13365] synonym: "segmentum hepatis i" EXACT LATIN [FMA:TA, FMA:13365] xref: FMA:13365 ! Caudate lobe of liver xref: VHOG:0000508 ! liver caudate lobe xref: MA:0000364 ! liver caudate lobe xref: ncithesaurus:Lobus_Caudatus ! Caudate Lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Gray1087-liver.png/200px-Gray1087-liver.png xref: EHDAA2:0001005 ! liver right caudate lobe xref: EMAPA:18313 ! caudate lobe xref: EHDAA:6990 ! caudate lobe xref: SCTID:362184009 ! Entire caudate lobe of liver is_a: UBERON:0001114 {source="MA"} ! right lobe of liver relationship: part_of UBERON:0001115 {source="FMA"} ! left lobe of liver synonym: "segment hepatis posterius I, lobus caudatus" RELATED LATIN [Wikipedia:Caudate_lobe_of_liver] xref: http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png property_value: external_definition "The portion of the right lobe of the liver between the fissure of the ligamentum venosum and the bare area of the liver. It ends into the superior recess of the lesser peritoneal sac. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000508", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The caudate lobe is the only real and constant hepatic lobe of mammals (...) .[well established][VHOG]" xsd:string {external_class="VHOG:0000508", ontology="VHOG", source="PMID:1610084 Van Minh T\, Galizia G\, Lieto E\, Anatomy of the caudate lobe of the liver. New aspects and surgical applications. (Article in French) Annales de chirurgie (1992)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0227489 [Term] id: UBERON:0007324 name: pancreatic lobe comment: todo - check synonym: "lobulus pancreaticus" EXACT [FMA:16012] synonym: "pancreatic lobule" EXACT [FMA:16012] xref: FMA:16012 ! pancreatic lobule xref: MA:0000721 ! pancreas lobe is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000017 ! exocrine pancreas synonym: "pancreas lobe" EXACT [MA:0000721] [Term] id: UBERON:0001118 name: lobe of thyroid gland def: "The lobes of the thyroid gland are conical in shape, the apex of each being directed upward and lateralward as far as the junction of the middle with the lower third of the thyroid cartilage; the base looks downward, and is on a level with the fifth or sixth tracheal ring. Each lobe is about 5 cm. long; its greatest width is about 3 cm. , and its thickness about 2 cm. The lateral or superficial surface is convex, and covered by the skin, the superficial and deep fasciæ, the Sternocleidomastoideus, the superior belly of the Omohyoideus, the Sternohyoideus and Sternothyreoideus, and beneath the last muscle by the pretracheal layer of the deep fascia, which forms a capsule for the gland. The deep or medial surface is moulded over the underlying structures, viz. , the thyroid and cricoid cartilages, the trachea, the Constrictor pharyngis inferior and posterior part of the Cricothyreoideus, the esophagus (particularly on the left side of the neck), the superior and inferior thyroid arteries, and the recurrent nerves. The anterior border is thin, and inclines obliquely from above downward toward the middle line of the neck, while the posterior border is thick and overlaps the common carotid artery, and, as a rule, the parathyroids. [WP,unvetted]." [Wikipedia:Lobes_of_thyroid_gland] comment: This class was created automatically from a combination of ontologies synonym: "lobus (glandula thyroidea)" EXACT [] synonym: "thyroid gland lobe" EXACT [] synonym: "thyroid lobe" EXACT [] xref: FMA:13367 ! Lobe of thyroid gland xref: MA:0000131 ! thyroid gland lobe xref: ncithesaurus:Thyroid_Gland_Lobe ! Thyroid Gland Lobe xref: VHOG:0000732 ! thyroid lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9e/Gray1174.png/200px-Gray1174.png xref: EHDAA2:0002032 ! thyroid lobe xref: EMAPA:18196 ! lobe of thyroid of gland of foregut xref: EMAPA:18830 ! lobe of thyroid of gland of gut is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002046 ! thyroid gland xref: SCTID:245537001 ! Entire lobe of thyroid gland synonym: "lobuli glandulae thyroideae" RELATED LATIN [Wikipedia:Lobes_of_thyroid_gland] xref: http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray1174.png property_value: homology_notes "Thus, a thyroid capable of forming iodotyrosines and iodothyronines is present in all vertebrates. (...) Certain morphologic changes occur after the biochemical evolution of the thyroid has ceased. In the adult lamprey and in most bony fishes, the gland is not encapsulated. (...) In cartilaginous fish, the thyroid is encapsulated. In the higher vertebrate forms, the thyroid is a one- or two-lobed encapsulated structure.[well established][VHOG]" xsd:string {external_class="VHOG:0000732", ontology="VHOG", source="http://www.thyroidmanager.org/Chapter1/chapter01.htm", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0002046 {source="FMA-abduced-lr"} ! thyroid gland xref: UMLS:C0447647 [Term] id: UBERON:0001119 name: right lobe of thyroid gland synonym: "lobus dexter (glandula thyroidea)" EXACT [] synonym: "thyroid gland right lobe" EXACT [] synonym: "right thyroid lobe" EXACT [] xref: FMA:13368 ! Right lobe of thyroid gland xref: MA:0000729 ! thyroid gland right lobe xref: VHOG:0000733 ! right thyroid lobe xref: EHDAA2:0001759 ! right thyroid lobe intersection_of: UBERON:0001118 ! lobe of thyroid gland intersection_of: in_right_side_of UBERON:0002046 ! thyroid gland xref: ncithesaurus:Right_Thyroid_Gland_Lobe ! Right Thyroid Gland Lobe xref: SCTID:170482008 ! Entire right lobe of thyroid gland xref: EMAPA:18198 ! right property_value: homology_notes "Thus, a thyroid capable of forming iodotyrosines and iodothyronines is present in all vertebrates. (...) Certain morphologic changes occur after the biochemical evolution of the thyroid has ceased. In the adult lamprey and in most bony fishes, the gland is not encapsulated. (...) In cartilaginous fish, the thyroid is encapsulated. In the higher vertebrate forms, the thyroid is a one- or two-lobed encapsulated structure.[well established][VHOG]" xsd:string {external_class="VHOG:0000733", ontology="VHOG", source="http://www.thyroidmanager.org/Chapter1/chapter01.htm", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A lobe of thyroid gland that is in the right side of a thyroid gland." [OBOL:automatic] xref: UMLS:C0229581 [Term] id: UBERON:0001120 name: left lobe of thyroid gland synonym: "lobus sinister (glandula thyroidea)" EXACT [] synonym: "thyroid gland left lobe" EXACT [] synonym: "left thyroid lobe" EXACT [] xref: FMA:13369 ! Left lobe of thyroid gland xref: MA:0000728 ! thyroid gland left lobe xref: VHOG:0000734 ! left thyroid lobe xref: EHDAA2:0000965 ! left thyroid lobe intersection_of: UBERON:0001118 ! lobe of thyroid gland intersection_of: in_left_side_of UBERON:0002046 ! thyroid gland xref: ncithesaurus:Left_Thyroid_Gland_Lobe ! Left Thyroid Gland Lobe xref: SCTID:170784008 ! Entire left lobe of thyroid gland xref: EMAPA:18197 ! left property_value: homology_notes "Thus, a thyroid capable of forming iodotyrosines and iodothyronines is present in all vertebrates. (...) Certain morphologic changes occur after the biochemical evolution of the thyroid has ceased. In the adult lamprey and in most bony fishes, the gland is not encapsulated. (...) In cartilaginous fish, the thyroid is encapsulated. In the higher vertebrate forms, the thyroid is a one- or two-lobed encapsulated structure.[well established][VHOG]" xsd:string {external_class="VHOG:0000734", ontology="VHOG", source="http://www.thyroidmanager.org/Chapter1/chapter01.htm", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A lobe of thyroid gland that is in the left side of a thyroid gland." [OBOL:automatic] xref: UMLS:C0229582 [Term] id: UBERON:0001121 name: longus colli muscle def: "The Longus colli muscle is a muscle of the human body. The Longus colli is situated on the anterior surface of the vertebral column, between the atlas and the third thoracic vertebra. It is broad in the middle, narrow and pointed at either end, and consists of three portions, a superior oblique, an inferior oblique, and a vertical. The superior oblique portion arises from the anterior tubercles of the transverse processes of the third, fourth, and fifth cervical vertebræ and, ascending obliquely with a medial inclination, is inserted by a narrow tendon into the tubercle on the anterior arch of the atlas. The inferior oblique portion, the smallest part of the muscle, arises from the front of the bodies of the first two or three thoracic vertebræ; and, ascending obliquely in a lateral direction, is inserted into the anterior tubercles of the transverse processes of the fifth and sixth cervical vertebræ. The vertical portion arises, below, from the front of the bodies of the upper three thoracic and lower three cervical vertebræ, and is inserted into the front of the bodies of the second, third, and fourth cervical vertebræ. [WP,unvetted]." [Wikipedia:Longus_colli_muscle] synonym: "longi colli" RELATED [Wikipedia:Longus_colli_muscle] synonym: "longus colli muscle" EXACT [Wikipedia:Longus_colli_muscle] synonym: "longus colli" EXACT [MA:0002341] synonym: "musculus longus colli" RELATED LATIN [Wikipedia:Longus_colli_muscle] subset: uberon_slim xref: FMA:13370 ! Longus colli xref: MA:0002341 ! longus colli xref: ncithesaurus:Longus_Colli ! Longus Colli xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a6/Longus_colli.png/200px-Longus_colli.png xref: SCTID:244836009 ! Entire longus colli xref: http://upload.wikimedia.org/wikipedia/commons/a/a6/Longus_colli.png subset: organ_slim is_a: UBERON:0001630 ! muscle organ relationship: located_in UBERON:0008818 {source="FMA-modified"} ! superior mediastinum relationship: has_muscle_origin UBERON:0001077 {source="dbpedia", notes="Transverse processes of C-5 to T-3"} ! transverse process of vertebra relationship: has_muscle_insertion UBERON:0003996 {source="dbpedia"} ! arcus anterior xref: UMLS:C0224169 [Term] id: UBERON:0001122 name: scalenus medius def: "The Scalenus medius, the largest and longest of the three scalene muscles, arises from the posterior tubercles of the transverse processes of the lower six cervical vertebræ. It descendes along the side of the vertebral column to insert by a broad attachment into the upper surface of the first rib, between the tubercle and the subclavian groove. The brachial plexus and the subclavian artery pass anterior to it. Because it elevates the upper ribs, the middle scalene muscle is also one of the accessory muscles of respiration. [WP,unvetted]." [Wikipedia:Scalenus_medius] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "medial scalene muscle" EXACT [] synonym: "scalenus medius muscle" EXACT [] synonym: "middle scalene" EXACT [] xref: FMA:13386 ! Scalenus medius xref: MA:0002370 ! scalenus medius xref: ncithesaurus:Scalenus_Medius ! Scalenus Medius xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fa/Scalenus_medius.png/200px-Scalenus_medius.png is_a: UBERON:0002377 ! muscle of neck synonym: "musculus scalenus medius" EXACT LATIN [FMA:TA, FMA:13386] relationship: has_muscle_insertion UBERON:0004601 {source="dbpedia"} ! rib 1 relationship: has_muscle_origin UBERON:0002413 {source="dbpedia"} ! cervical vertebra synonym: "musculus scalenus medius" RELATED LATIN [Wikipedia:Scalenus_medius] relationship: innervated_by UBERON:0000962 {source="dbpedia", notes="Ventral rami of the third to eighth cervical spinal nerves"} ! cervical nerve xref: http://upload.wikimedia.org/wikipedia/commons/f/fa/Scalenus_medius.png xref: SCTID:244844009 ! Entire scalenus medius muscle xref: UMLS:C0224174 [Term] id: UBERON:0001123 name: scalenus posterior def: "The Scalenus posterior (Scalenus posticus), the smallest and most deeply seated of the three Scaleni, arises, by two or three separate tendons, from the posterior tubercles of the transverse processes of the lower two or three cervical vertebræ, and is inserted by a thin tendon into the outer surface of the second rib, behind the attachment of the Serratus anterior. It is occasionally blended with the Scalenus medius. [WP,unvetted]." [Wikipedia:Scalenus_posterior] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "posterior scalene" EXACT [] synonym: "posterior scalene muscle" EXACT [] synonym: "scalenus dorsalis" EXACT [] synonym: "scalenus dorsalis muscle" EXACT [] xref: FMA:13387 ! Scalenus posterior xref: MA:0002369 ! scalenus dorsalis xref: ncithesaurus:Scalenus_Dorsalis ! Scalenus Dorsalis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f3/Scalenus_posterior.png/200px-Scalenus_posterior.png is_a: UBERON:0002377 ! muscle of neck synonym: "musculus scalenus posterior" EXACT LATIN [FMA:TA, FMA:13387] synonym: "musculus scalenus posterior" RELATED LATIN [Wikipedia:Scalenus_posterior] relationship: has_muscle_origin UBERON:0001077 {source="dbpedia", notes="transverse processes of C4 - C6"} ! transverse process of vertebra xref: http://upload.wikimedia.org/wikipedia/commons/f/f3/Scalenus_posterior.png xref: UMLS:C1710019 [Term] id: UBERON:0001125 name: serratus anterior def: "The serratus anterior is a muscle that originates on the surface of the upper eight or nine ribs at the side of the chest and inserts along the entire anterior length of the medial border of the scapula. [WP,unvetted]." [Wikipedia:Serratus_anterior_muscle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "Boxer's muscle" EXACT [] synonym: "serratus anterior muscle" EXACT [] synonym: "serratus ventralis" EXACT [] xref: FMA:13397 ! Serratus anterior xref: VHOG:0000679 ! serratus anterior xref: MA:0002378 ! serratus ventralis xref: OpenCyc:Mx4rvWn_D5wpEbGdrcN5Y29ycA xref: ncithesaurus:Serratus_Ventralis ! Serratus Ventralis xref: EHDAA:9463 ! serratus anterior xref: OpenCyc:Mx4rvWn_D5wpEbGdrcN5Y29ycA ! serratus anterior muscle xref: EHDAA2:0001832 ! serratus anterior xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c6/Serratus_anterior.png/200px-Serratus_anterior.png xref: EMAPA:18525 ! serratus anterior is_a: UBERON:0001482 ! muscle of shoulder relationship: develops_from UBERON:0010986 {source="EHDAA2"} ! serratus anterior pre-muscle mass xref: SCTID:181748003 ! Entire serratus anterior muscle relationship: has_muscle_antagonist UBERON:0002380 {source="dbpedia"} ! trapezius synonym: "musculus serratus anterior, serratus lateralis" RELATED LATIN [Wikipedia:Serratus_anterior_muscle] relationship: has_muscle_insertion UBERON:0006849 {source="dbpedia", notes="costal aspect of medial margin of the scapula"} ! scapula relationship: innervated_by UBERON:0003726 {source="dbpedia", notes="long thoracic nerve"} ! thoracic nerve relationship: has_muscle_origin UBERON:0002228 {source="dbpedia", notes="fleshy slips from the outer surface of upper 8 or 9 ribs"} ! rib xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Serratus_anterior.png xref: UMLS:C1710059 [Term] id: UBERON:0010986 name: serratus anterior pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0003897 {source="EHDAA2"} ! axial muscle xref: EHDAA2:0001833 ! serratus anterior pre-muscle mass [Term] id: UBERON:0011217 name: serratus posterior synonym: "serratus posterior muscle" EXACT [FMA:13400] is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column relationship: innervated_by UBERON:0003727 {source="dbpedia-abduced"} ! intercostal nerve relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia-abduced"} ! rib xref: FMA:13400 ! serratus posterior xref: SCTID:244934006 ! Entire serratus posterior muscle [Term] id: UBERON:0001126 name: serratus posterior superior muscle def: "The Serratus posterior superior is a thin, quadrilateral muscle, situated at the upper and back part of the thorax. It arises by a thin and broad aponeurosis from the lower part of the ligamentum nuchae, from the spinous processes of the seventh cervical and upper two or three thoracic vertebræ and from the supraspinal ligament. Inclining downward and lateralward it becomes muscular, and is inserted, by four fleshy digitations, into the upper borders of the second, third, fourth, and fifth ribs, a little beyond their angles. [WP,unvetted]." [Wikipedia:Serratus_posterior_superior_muscle] subset: uberon_slim synonym: "superior serratus posterior" EXACT [] synonym: "serratus dorsalis cranialis" EXACT [MA:0002377] synonym: "serratus dorsalis cranialis muscle" EXACT [] synonym: "serratus posterior superior" EXACT [FMA:13401] xref: FMA:13401 ! serratus posterior superior xref: MA:0002377 ! serratus dorsalis cranialis xref: ncithesaurus:Serratus_Dorsalis_Cranialis ! Serratus Dorsalis Cranialis is_a: UBERON:0011217 {source="FMA"} ! serratus posterior relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="rib 2 thru 5 in human"} ! rib relationship: has_muscle_origin UBERON:0000351 ! nuchal ligament relationship: has_muscle_origin UBERON:0001076 {source="dbpedia", notes="C7 thru T3 in human"} ! spinous process of vertebra relationship: innervated_by UBERON:0003727 {source="dbpedia", notes="2 thru 5 in human"} ! intercostal nerve xref: SCTID:244935007 ! Serratus posterior superior xref: UMLS:C1710058 [Term] id: UBERON:0001127 name: serratus posterior inferior muscle def: "The Serratus posterior inferior muscle (or posterior serratus) is a muscle of the human body. [WP,unvetted]." [Wikipedia:Serratus_posterior_inferior_muscle] subset: uberon_slim synonym: "inferior serratus posterior" EXACT [] synonym: "serratus dorsalis caudalis" EXACT [] xref: FMA:13402 ! Serratus posterior inferior xref: MA:0002376 ! serratus dorsalis caudalis xref: ncithesaurus:Serratus_Dorsalis_Caudalis ! Serratus Dorsalis Caudalis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Serratus_posterior.PNG/200px-Serratus_posterior.PNG is_a: UBERON:0011217 {source="FMA"} ! serratus posterior relationship: has_muscle_origin UBERON:0002412 {source="dbpedia", notes="T11 through L2 in human"} ! vertebra relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="inferior border of 9th thru 12th in humans"} ! rib relationship: innervated_by UBERON:0003727 {source="dbpedia", notes="T9 through T12 in human"} ! intercostal nerve xref: SCTID:244936008 ! Serratus posterior inferior xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Serratus_posterior.PNG/250px-Serratus_posterior.PNG synonym: "serratus posterior inferior" EXACT [FMA:13402] synonym: "serratus posterior inferior" RELATED [MA:0002376] xref: UMLS:C1711277 [Term] id: UBERON:0010946 name: occipitofrontalis muscle def: "The occipitofrontalis or epicranius is a muscle which covers parts of the skull. It consists of two parts or bellies: The occipital belly, near the occipital bone, and the frontal belly, near the frontal bone. Some sources consider the occipitofrontalis to be a structure consisting of two distinct muscles, the Frontalis and the occipitalis. However, Terminologia Anatomica currently classifies it as a single muscle." [Wikipedia:Occipitofrontalis_muscle] comment: zone of muscle in FMA synonym: "epicranius" RELATED [Wikipedia:Occipitofrontalis_muscle] synonym: "occipitofrontalis" RELATED [Wikipedia:Occipitofrontalis_muscle] is_a: UBERON:0002376 ! muscle of head xref: FMA:9624 ! occipitofrontalis xref: SCTID:361811007 ! Entire occipitofrontalis muscle xref: ncithesaurus:Occipito-frontalis_Muscle relationship: has_muscle_insertion UBERON:0006661 {source="dbpedia"} ! epicranial aponeurosis relationship: innervated_by UBERON:0001647 {source="dbpedia"} ! facial nerve synonym: "musculus occipitofrontalis" RELATED LATIN [Wikipedia:Occipitofrontalis_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray378.png xref: UMLS:C1518531 [Term] id: UBERON:0010947 name: occipitalis synonym: "occipital belly of occipitofrontalis" EXACT [FMA:46758] synonym: "occipital part of occipitofrontalis" EXACT [FMA:46758] synonym: "venter occipitalis (musculus occipitofrontalis)" EXACT [FMA:46758] synonym: "venter transversa musculus occipitofrontalis occipitalis" EXACT LATIN [FMA:TA] is_a: UBERON:0010938 ! muscle belly relationship: part_of UBERON:0010946 {source="FMA"} ! occipitofrontalis muscle xref: FMA:46758 ! occipitalis xref: SCTID:21405000 ! Structure of occipital belly of occipitofrontalis muscle [Term] id: UBERON:0010948 name: cleidooccipital muscle comment: Some studies have indicated a supernumerary cleido-occipital muscle more or less separate from the sterno-cleido-mastoid muscle; The frequency of cleido-occipital muscle occurrence has been reported up to 33% synonym: "cleido-occipitalis" EXACT [] synonym: "cleido-occipitalis muscle" EXACT [] is_a: UBERON:0000933 ! pharyngeal muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0001105 ! clavicle intersection_of: attaches_to UBERON:0001676 ! occipital bone xref: MA:0002276 ! cleidooccipital synonym: "cleidooccipital" EXACT [MA:0002276] def: "A muscle organ that attaches_to a clavicle and attaches_to a occipital bone." [OBOL:automatic] [Term] id: UBERON:0010949 name: sternooccipital muscle is_a: UBERON:0002377 ! muscle of neck intersection_of: UBERON:0001630 ! muscle organ intersection_of: has_muscle_origin UBERON:0000975 ! sternum intersection_of: has_muscle_insertion UBERON:0001676 ! occipital bone synonym: "sternooccipital" EXACT [MA:0002385] xref: MA:0002385 ! sternooccipital xref: ncithesaurus:Sternooccipital ! sternooccipital def: "A muscle organ that has_muscle_insertion a occipital bone and has_muscle_origin a sternum." [OBOL:automatic] xref: UMLS:C1710196 [Term] id: UBERON:0001128 name: sternocleidomastoid def: "a paired muscle in the superficial layers of the anterior portion of the neck. It acts to flex and rotate the head. It also acts as an accessory muscle of inspiration, along with the scalene muscles of the neck. [WP,unvetted]." [Wikipedia:Sternocleidomastoid_muscle] comment: Editor notes: TODO: sternocleidomastoid = sternomastoid + Cleidomastoideus. Origin: from manubrium sterni (sterno) and clavicle (cleido) and it's insertion at the mastoid process of the temporal bone. subset: uberon_slim synonym: "sterno-cleido-mastoid" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sterno-mastoid" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternocleidomastoid" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternocleidomastoid muscles" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternocleidomastoidei" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternocleidomastoideus" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternocleidomastoideus muscle" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternocleidomastoids" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternomastoid" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternomastoid muscle" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "supraclavicularis muscle" RELATED [Wikipedia:Sternocleidomastoid_muscle] synonym: "sternocleidomastoid muscle" EXACT [BTO:0005125] synonym: "sternomastoid" EXACT [] synonym: "sternomastoid muscle" EXACT [] synonym: "sterno-mastoid" EXACT [] synonym: "SCM" BROAD ABBREVIATION [] xref: FMA:13407 ! Sternocleidomastoid xref: MA:0002384 ! sternomastoid xref: OpenCyc:Mx4rv2bMg5wpEbGdrcN5Y29ycA xref: ncithesaurus:Sternocleidomastoid_Muscle ! Sternocleidomastoid Muscle xref: OpenCyc:Mx4rv2bMg5wpEbGdrcN5Y29ycA ! sternocleidomastoid muscle xref: VHOG:0000853 ! sterno-mastoid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/61/Gray512.png/200px-Gray512.png xref: EMAPA:25137 ! sterno-mastoid xref: BTO:0005125 ! sternocleidomastoid muscle is_a: UBERON:0002377 ! muscle of neck relationship: develops_from UBERON:0010987 ! sterno-mastoid pre-muscle mass xref: SCTID:181741009 ! Entire sternocleidomastoid muscle synonym: "musculus sternocleidomastoideus" RELATED LATIN [Wikipedia:Sternocleidomastoid_muscle] relationship: innervated_by UBERON:0003725 {source="dbpedia", notes="sensory: cervical plexus"} ! cervical plexus relationship: has_muscle_origin UBERON:0002205 {source="dbpedia", notes="manubrium sterni medial portion of the clavicle"} ! manubrium of sternum relationship: has_muscle_origin UBERON:0001105 {source="dbpedia", notes="manubrium sterni medial portion of the clavicle"} ! clavicle relationship: has_muscle_insertion UBERON:0011220 {source="Wikipedia:Mastoid_process"} ! mastoid process of temporal bone xref: http://upload.wikimedia.org/wikipedia/commons/f/f9/Gray512.svg property_value: homology_notes "The sternomastoid and the three parts of the trapezius are branchiomeric muscles that have secondarily acquired an attachment to the pectoral girdle. They evolved from the fish cucullaris.[well established][VHOG]" xsd:string {external_class="VHOG:0000853", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.345", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0224153 [Term] id: UBERON:0011371 name: sternocephalicus muscle def: "The sternocephalicus is a flat muscle and its caudal border is adjacent to the ventral border of the brachiocephalicus. The lateral aspect of this muscle is crossed obliquely by the external jugular vein. It originates as a unit on the first sternebrae. The cranial portion of the muscle divides into two separate sections with different insertion points. These are the sternomastoideus and the sterno-occipitalis. The ventral portion, the sternomastiodeus is the stronger and main continuation of the sternocephalicus, which inserts on the mastoid part of the temporal bone. The thin but wide dorsal segment, the sterno-occipitalis attaches to the dorsal nuchal crest by a thin aponeurosis. The main action provided by the sternocephalicus is movement of the head and neck to the side. Ventral branches of the cervical nerves are attached to this muscle." [MURDOCH:1749] synonym: "sternocephalicus" EXACT [] intersection_of: UBERON:0001630 ! muscle organ intersection_of: has_muscle_origin UBERON:0002208 ! sternebra intersection_of: has_muscle_insertion UBERON:0011220 ! mastoid process of temporal bone intersection_of: has_muscle_insertion UBERON:0001676 ! occipital bone relationship: has_muscle_insertion UBERON:0001676 {notes="nuchal crest"} ! occipital bone xref: SCTID:21636001 ! Sternocephalicus muscle [Term] id: UBERON:0011364 ! cleidocephalicus muscle name: cleidocephalicus muscle def: "The cleidomastoideus is a thick, strap-like muscle that together with the cleidocervicalis forms the proximal part of the brachiocephalicus. It lies beneath the cleidocervicalis. Its origin is the clavicular tendon with its insertion being at the mastoid process of the temporal bone. It is distinctly narrow and is united with the cleidocervicalis and cleidobrachialis by the clavicular tendon. Together with the other two components of the brachiocephalicus muscle, its primary function is to advance the free limb, however, it can also act as an shoulder extensor. Acting bilaterally, it fixes and depresses the neck, while by its unilateral action, it allows the head and neck to be drawn to the side. Its blood supply is the inferior cervical, carotid and vertebral arteries and its nerve supply is the spinal accessory, cervical and axillary nerves." [MURDOCH:379] comment: alt def: "Combination of cleidomastoid and cleidocervical muscles" intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0001105 ! clavicle intersection_of: attaches_to UBERON:0011220 ! mastoid process of temporal bone relationship: has_muscle_origin UBERON:0001105 ! clavicle relationship: has_muscle_insertion UBERON:0011220 ! mastoid process of temporal bone relationship: part_of UBERON:0011368 ! brachiocephalic muscle synonym: "pars mastoideus" RELATED [] synonym: "cleidomastoid" RELATED [] synonym: "cleidomastoid muscle" RELATED [] synonym: "cleidomastoideus" RELATED [] synonym: "cleidocephalic" EXACT [MA:0002275] synonym: "cleidocephalicus" EXACT [] synonym: "cleidocephalic muscle" EXACT [] xref: MA:0002275 ! cleidocephalic xref: ncithesaurus:Cleidocephalic ! cleidocephalic xref: UMLS:C1707412 [Term] id: UBERON:0011366 name: cleidobrachialis muscle def: "This muscle makes up the distal segment of the brachiocephalicus. It originates at the clavicular tendon but functionally, from the head and neck through the cleidocervicalis. It inserts at the distal end of the cranial border of the humerus, where it lies between the biceps brachii medially and the brachialis laterally. The muscle partly covers the pectoral muscles at their insertions. In conjunction with the cleidocervicalis, it advances the limb, extends the shoulder and causes lateral movement of the head and neck." [MURDOCH:376] intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0001105 ! clavicle intersection_of: attaches_to UBERON:0000976 ! humerus intersection_of: part_of UBERON:0011364 ! cleidocephalicus muscle relationship: has_muscle_origin UBERON:0001105 ! clavicle relationship: has_muscle_insertion UBERON:0000976 ! humerus synonym: "cleidobrachialis" EXACT [] synonym: "cleidobrachial muscle" EXACT [] xref: MA:0002274 ! cleidobrachial xref: ncithesaurus:Cleidobrachial ! cleidobrachial synonym: "cleidobrachial" EXACT [MA:0002274] xref: UMLS:C1707411 [Term] id: UBERON:0011368 ! brachiocephalic muscle name: brachiocephalic muscle def: "The brachiocephalicus is a long and flat, complex of muscles that extends from the lower half of the humeral shaft to the head and neck. The muscle divides into two parts at the clavicular intersection. This is also the point of origin for all the muscles that make up the brachiocephalicus. This point is situated just cranial to the shoulder. The two main sections are the cleidobrachialis which is distal to the clavicular intersection and the cleidocephalicus which extends proximally to the clavivular intersection. The cleidocephalicus can also be divided into the pars cervicalis, which inserts on the broad aponeurosis, over the fibrous raphe of the cranial half of the neck. The other part, the pars mastoideus inserts on the mastoid process of the temporal bone via a strong tendon. The cleidobrachialis extends distally from the clavicular intersection and inserts on the cranial edge of the distal half of the humerus. The tendon that inserts the cleidobrachialis lies between the brachialis muscle and the biceps brachii. As a result of the brachiocephalicus spanning a large region it has the ability to provide a number of actions. These include extending the shoulder joint, protracts the limb, provides lateral movement of the head and allows the neck to be depressed." [http://ccg.murdoch.edu.au/museum/] comment: The brachiocephalicus is more complex than other muscles of the forelimb. It consists of 2 elements that unite at the clavicle in dogs. In dogs the caudal part, known as the cleidobrachialis, runs from the clavicle to the humerus and is closely associated with the deltoid. The cranial portion runs from the clavicle to various attachments via a broad aponeurosis on the upper part of the head and neck. It is called the cleidomastoideus in the dog because it inserts on the mastoid process of the temporal bone. It may have a different name, like cleido-occipitalis, in other mammals. The name brachiocephalicus signifies that this complex of muscles runs from the upper arm to the head and does not specify the details of muscle attachments because these vary so much from species to species. The brachiocephalicus advances the limb and may also extend the shoulder joint, but this depends on the cranial attachment being fixed and the limb being free to move. However, when the forelimb is firmly on the ground and the head is free to move, it forces the head and neck either ventrally or to one side depending on whether or not both muscles act in tandem intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0000976 ! humerus intersection_of: attaches_to UBERON:0011220 ! mastoid process of temporal bone synonym: "brachiocephalicus" BROAD [] [Term] id: UBERON:0011369 name: omotransversarius muscle def: "The omotransversarius is a straplike muscle, which advances and adducts the forelimb, as well as flexes the neck laterally. It covers the transverse processes of the cervical vertebrae, lying to their side. The omotransversarius lies ventral to the trapezius, cranial to the deltoid muscle and is covered cranially by the cleidocervicalis. It extends from the atlas to the spine of the scapula, with its origin on the transverse process of the atlas and its insertion in the distal end of the spine of the scapula. Its name can be split into omo, which is Greek for shoulder, and tranversarius which relates to its attachment to the transverse process of the atlas. This muscle is innervated by the accessory nerve." [MURDOCH:1433] synonym: "omotransverse muscle" EXACT [] synonym: "omotransverse" EXACT [MA:0002349] intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0011370 ! transverse process of atlas intersection_of: attaches_to UBERON:0004651 ! scapula spine xref: MA:0002349 ! omotransverse xref: ncithesaurus:Omotransverse ! omotransverse xref: UMLS:C1709311 [Term] id: UBERON:0011370 ! transverse process of atlas name: transverse process of atlas intersection_of: UBERON:0001077 ! transverse process of vertebra intersection_of: part_of UBERON:0001092 ! cervical vertebra 1 xref: FMA:23981 ! transverse process of atlas xref: SCTID:181895009 ! Transverse process of atlas relationship: in_lateral_side_of UBERON:0001092 {source="FMA-abduced-lr"} ! cervical vertebra 1 def: "A transverse process of vertebra that is part of a cervical vertebra 1." [OBOL:automatic] [Term] id: UBERON:0010987 ! sterno-mastoid pre-muscle mass name: sterno-mastoid pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0002376 {source="EHDAA2"} ! muscle of head xref: EHDAA2:0001913 ! sterno-mastoid pre-muscle mass [Term] id: UBERON:0001129 name: subscapularis muscle def: "The subscapularis is a large triangular muscle which fills the subscapular fossa and inserts into the lesser tubercle of the humerus and the front of the capsule of the shoulder-joint. [WP,unvetted]." [Wikipedia:Subscapularis_muscle] subset: uberon_slim synonym: "subscapularis" EXACT [MA:0002388] synonym: "subcoracoscapularis" RELATED SENSU [ISBN10:0073040584] xref: EHDAA:8317 ! subscapularis xref: FMA:13413 ! Subscapularis xref: VHOG:0000850 ! subscapularis xref: MA:0002388 ! subscapularis xref: ncithesaurus:Subscapularis ! Subscapularis xref: OpenCyc:Mx4rviCRIJwpEbGdrcN5Y29ycA ! subscapularis muscle xref: EHDAA2:0001943 ! subscapularis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Gray411.png/200px-Gray411.png xref: EMAPA:18181 ! subscapularis is_a: UBERON:0001482 ! muscle of shoulder relationship: develops_from UBERON:0010993 ! subscapularis pre-muscle mass relationship: part_of UBERON:0003683 {source="Wikipedia"} ! rotator cuff relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle xref: SCTID:277446000 ! Entire subscapularis synonym: "musculus subscapularis" RELATED LATIN [Wikipedia:Subscapularis_muscle] relationship: has_muscle_insertion UBERON:0000976 {source="dbpedia", notes="lesser tubercle of humerus"} ! humerus xref: http://upload.wikimedia.org/wikipedia/commons/f/f2/Gray411.png xref: UMLS:C0584884 [Term] id: UBERON:0010993 ! subscapularis pre-muscle mass name: subscapularis pre-muscle mass is_a: UBERON:0005865 ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group xref: EMAPA:17750 ! subscapularis pre-muscle mass [Term] id: UBERON:0011251 name: levator claviculae muscle def: "A skeletal muscle in the posterior triangle of the neck. It originates on the transverse processes of the upper cervical vertebrae and is inserted in the lateral half of the clavicle" [Wikipedia:Levator_claviculae_muscle] comment: Taxon notes: The levator claviculae is an infrequently recognized anatomical variant in humans, distinguished from, for example, cervical adenopathy or a thrombosed vein, but a normal muscle in lower mammals and anthropoids. In humans, when present, it often appears unilaterally, most commonly on the left side, or bilaterally.[WP] synonym: "omocervicalis" EXACT [Wikipedia:Levator_claviculae_muscle] synonym: "levator claviculae" EXACT [Wikipedia:Levator_claviculae_muscle] synonym: "musculus levator claviculae" EXACT LATIN [Wikipedia:Levator_claviculae_muscle] synonym: "cleidocervicalis muscle" EXACT [Wikipedia:Levator_claviculae_muscle] synonym: "cleidocervicalis" EXACT [Wikipedia:Levator_claviculae_muscle] synonym: "tracheloacromial muscle" EXACT [Wikipedia:Levator_claviculae_muscle] synonym: "pars cervicalis" RELATED [] is_a: UBERON:0002377 ! muscle of neck relationship: has_muscle_insertion UBERON:0001105 {source="Wikipedia", notes="lateral half"} ! clavicle relationship: has_muscle_origin UBERON:0001077 {source="dbpedia", notes="nterior portion of transverse processes of C1 - C4 vertebrae"} ! transverse process of vertebra relationship: has_muscle_origin UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0011364 ! cleidocephalicus muscle property_value: external_definition "Cleidocervicalis is one of two muscles, which make up the cleidocephalic component of the complex brachiocephalic muscle. It is a thin triangular muscle which has a broad origin on the median raphe of the mid dorsal aspect of the neck. The muscle is bounded caudally by the trapezius and cranially by the occipital component of the sternocephalicus . The cleidocervicalis tapers as it passes ventrally across the side of the neck to insert into the clavicular tendon. It is innervated by the accessory nerve. The brachiocephalic complex advances the limb, extends the shoulder joint and fixes the neck." xsd:string {source="MURDOCH:378"} [Term] id: UBERON:0010952 name: frontalis def: "The frontalis muscle is thin, of a quadrilateral form, and intimately adherent to the superficial fascia. It is broader than the Occipitalis and its fibers are longer and paler in color. It is located on the front of the head. It has no bony attachments. Its medial fibers are continuous with those of the Procerus; its immediate fibers blend with the Corrugator and Orbicularis oculi, thus attached to the skin of the eyebrows; and its lateral fibers are also blended with the latter muscle over the zygomatic process of the frontal bone. In the eyebrows, its primary function is to lift them (thus opposing the orbital portion of the orbicularis), especially when looking up. It also acts when a view is too distant or dim. From these attachments the fibers are directed upward, and join the galea aponeurotica below the coronal suture. The medial margins of the Frontales are joined together for some distance above the root of the nose; but between the Occipitales there is a considerable, though variable, interval, occupied by the galea aponeurotica. It could be part of occipitofrontalis muscle." [Wikipedia:Frontalis_muscle] synonym: "frontal belly of occipitofrontalis muscle" RELATED [Wikipedia:Frontalis_muscle] synonym: "frontal belly of occipitofrontalis" EXACT [FMA:46757] synonym: "frontal part of occipitofrontalis" EXACT [FMA:46757] synonym: "venter frontalis (musculus occipitofrontalis)" EXACT [FMA:46757] synonym: "venter frontalis musculus occipitofrontalis" EXACT LATIN [FMA:TA] synonym: "orbito-temporo-auricularis" EXACT [PMID:18657257] is_a: UBERON:0010938 ! muscle belly relationship: part_of UBERON:0010946 {source="FMA"} ! occipitofrontalis muscle xref: FMA:46757 ! frontalis xref: SCTID:368680005 ! Entire frontal belly of occipitofrontalis muscle relationship: innervated_by UBERON:0001647 {source="dbpedia"} ! facial nerve relationship: has_muscle_origin UBERON:0006661 {source="dbpedia"} ! epicranial aponeurosis synonym: "venter frontalis musculi occipitofrontalis" RELATED LATIN [Wikipedia:Frontalis_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/b/be/Musculus_frontalis.png [Term] id: UBERON:0010953 name: nasalis muscle def: "The nasalis (compressor naris) is a sphincter-like muscle of the nose whose function is to compress the nasal cartilage. It consists of two parts, transverse and alar: The transverse part arises from the maxilla, above and lateral to the incisive fossa; its fibers proceed upward and medially, expanding into a thin aponeurosis which is continuous on the bridge of the nose with that of the muscle of the opposite side, and with the aponeurosis of the Procerus. The alar part is attached at one end to the greater alar cartilage, and at the other to the integument at the point of the nose. Other sources divide it into \"Compressor nasalis\" and \"Dilator nasalis\"." [Wikipedia:Nasalis_muscle] synonym: "compressor naris" RELATED [Wikipedia:Nasalis_muscle] synonym: "compressor narium minor" RELATED [Wikipedia:Nasalis_muscle] synonym: "compressor nasi" RELATED [Wikipedia:Nasalis_muscle] synonym: "nasalis" EXACT [FMA:46770] is_a: UBERON:0008522 {source="FMA"} ! nasal muscle xref: FMA:46770 ! nasalis xref: SCTID:244732001 ! Entire nasalis relationship: has_muscle_insertion UBERON:0001681 {source="dbpedia"} ! nasal bone relationship: has_muscle_origin UBERON:0002397 {source="dbpedia"} ! maxilla synonym: "musculus nasalis" RELATED LATIN [Wikipedia:Nasalis_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/b/bb/Nasalis.png relationship: in_lateral_side_of UBERON:0000004 {source="FMA-abduced-lr"} ! olfactory apparatus [Term] id: UBERON:0010276 name: vertebral column opening comment: AO notes: in AAO this is a space rather than conduit xref: AAO:0000700 ! vertebral column opening synonym: "vertebral conduit" EXACT [] intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: part_of UBERON:0002412 ! vertebra def: "An anatomical conduit that is part of a vertebra." [OBOL:automatic] [Term] id: UBERON:0001131 name: vertebral foramen def: "In a typical vertebra, the vertebral foramen is the foramen formed by the anterior segment, and the posterior part, the vertebral arch. The vertebral foramen begins at cervical vertebrae #1 and continues inferior to lumbar vertebrae #5. Within this foramen the spinal cord and associated meninges are housed. [WP,unvetted]." [Wikipedia:Vertebral_foramen] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "vertebra neural canal" EXACT [] xref: FMA:13479 ! Vertebral foramen xref: MA:0001454 ! vertebra neural canal xref: AAO:0000729 ! spinal foramen xref: OpenCyc:Mx4rv_EvQZwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rv_EvQZwpEbGdrcN5Y29ycA ! vertebral foramen xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/10/Foramenvertebrale.png/200px-Foramenvertebrale.png is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0002412 ! vertebra xref: SCTID:280734009 ! Vertebral foramen synonym: "foramen vertebrale" RELATED LATIN [Wikipedia:Vertebral_foramen] xref: http://upload.wikimedia.org/wikipedia/commons/1/10/Foramenvertebrale.png property_value: external_definition "Opening on the vertebra for a spinal nerve as it emerges from the spinal canal.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000729", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0008429 name: cervical vertebral foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0002413 ! cervical vertebra xref: FMA:13480 ! cervical vertebral foramen xref: SCTID:280833008 ! Cervical vertebral foramen def: "A vertebral foramen that is part of a cervical vertebra." [OBOL:automatic] [Term] id: UBERON:0008430 name: lumbar vertebral foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0002414 ! lumbar vertebra xref: FMA:24826 ! lumbar vertebral foramen xref: SCTID:280835001 ! Lumbar vertebral foramen def: "A vertebral foramen that is part of a lumbar vertebra." [OBOL:automatic] [Term] id: UBERON:0008431 name: sacral foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0001094 ! sacral vertebra xref: FMA:31749 ! sacral foramen def: "A vertebral foramen that is part of a sacral vertebra." [OBOL:automatic] [Term] id: UBERON:0008432 name: thoracic vertebral foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0002347 ! thoracic vertebra xref: FMA:9143 ! thoracic vertebral foramen xref: SCTID:280834002 ! Thoracic vertebral foramen def: "A vertebral foramen that is part of a thoracic vertebra." [OBOL:automatic] [Term] id: UBERON:0008433 name: lumbar vertebral arch synonym: "arch of lumbar vertebra" EXACT [FMA:16076] intersection_of: UBERON:0003861 ! vertebral arch intersection_of: part_of UBERON:0002414 ! lumbar vertebra xref: FMA:16076 ! lumbar vertebral arch xref: SCTID:312766000 ! Entire arch of lumbar vertebra def: "A neural arch that is part of a lumbar vertebra." [OBOL:automatic] [Term] id: UBERON:0008434 name: cervical vertebral arch synonym: "arch of cervical vertebra" EXACT [FMA:23893] intersection_of: UBERON:0003861 ! vertebral arch intersection_of: part_of UBERON:0002413 ! cervical vertebra xref: FMA:23893 ! cervical vertebral arch xref: SCTID:165269004 ! Entire arch of cervical vertebra def: "A neural arch that is part of a cervical vertebra." [OBOL:automatic] [Term] id: UBERON:0008435 name: vertebral arch of sacral segment intersection_of: UBERON:0003861 ! vertebral arch intersection_of: part_of UBERON:0001094 ! sacral vertebra xref: FMA:32401 ! vertebral arch of sacral segment def: "A neural arch that is part of a sacral vertebra." [OBOL:automatic] [Term] id: UBERON:0008436 name: thoracic vertebral arch synonym: "arch of thoracic vertebra" EXACT [FMA:9151] intersection_of: UBERON:0003861 ! vertebral arch intersection_of: part_of UBERON:0002347 ! thoracic vertebra xref: FMA:9151 ! thoracic vertebral arch xref: SCTID:312764002 ! Entire arch of thoracic vertebra def: "A neural arch that is part of a thoracic vertebra." [OBOL:automatic] [Term] id: UBERON:0008456 name: superior articular process of lumbar vertebra synonym: "cranial articular process of lumbar vertebra" EXACT [FMA:16126] intersection_of: UBERON:0001079 ! superior articular process of vertebra intersection_of: part_of UBERON:0002414 ! lumbar vertebra xref: FMA:16126 ! superior articular process of lumbar vertebra xref: SCTID:305677003 ! Entire superior articular process of lumbar vertebra def: "A superior articular process of vertebra that is part of a lumbar vertebra." [OBOL:automatic] [Term] id: UBERON:0008457 name: superior articular process of sacral vertebra synonym: "articular process of sacral segment" EXACT [FMA:16215] synonym: "processus articularis superior (os sacrum)" EXACT [FMA:16215] synonym: "processus articularis superior ossis sacri" EXACT LATIN [FMA:TA] synonym: "superior articular process of sacral segment" EXACT [FMA:16215] synonym: "superior articular process of sacrum" EXACT [FMA:16215] intersection_of: UBERON:0001079 ! superior articular process of vertebra intersection_of: part_of UBERON:0001094 ! sacral vertebra xref: FMA:16215 ! superior articular process of sacral vertebra def: "A superior articular process of vertebra that is part of a sacral vertebra." [OBOL:automatic] [Term] id: UBERON:0008459 name: superior articular process of cervical vertebra intersection_of: UBERON:0001079 ! superior articular process of vertebra intersection_of: part_of UBERON:0002413 ! cervical vertebra xref: FMA:23969 ! superior articular process of cervical vertebra xref: SCTID:57767002 ! Entire superior articular process of cervical vertebra def: "A superior articular process of vertebra that is part of a cervical vertebra." [OBOL:automatic] [Term] id: UBERON:0008460 name: superior articular process of thoracic vertebra synonym: "cranial articular process of thoracic vertebra" EXACT [FMA:9155] synonym: "processus articularis (zygapophysis) thoracicus superior" EXACT [FMA:9155] synonym: "superior apophyseal process" EXACT [FMA:9155] synonym: "superior zygapophysis" EXACT [FMA:9155] intersection_of: UBERON:0001079 ! superior articular process of vertebra intersection_of: part_of UBERON:0002347 ! thoracic vertebra xref: FMA:9155 ! superior articular process of thoracic vertebra xref: SCTID:367801006 ! Entire superior articular process of thoracic vertebra def: "A superior articular process of vertebra that is part of a thoracic vertebra." [OBOL:automatic] [Term] id: UBERON:0008461 name: inferior articular process of lumbar vertebra synonym: "caudal articular process of lumbar vertebra" EXACT [FMA:16127] intersection_of: UBERON:0001080 ! inferior articular process of vertebra intersection_of: part_of UBERON:0002414 ! lumbar vertebra xref: FMA:16127 ! inferior articular process of lumbar vertebra xref: SCTID:306283004 ! Entire inferior articular process of lumbar vertebra def: "An inferior articular process of vertebra that is part of a lumbar vertebra." [OBOL:automatic] [Term] id: UBERON:0008462 name: inferior articular process of cervical vertebra intersection_of: UBERON:0001080 ! inferior articular process of vertebra intersection_of: part_of UBERON:0002413 ! cervical vertebra xref: FMA:23970 ! inferior articular process of cervical vertebra xref: SCTID:61633005 ! Entire inferior articular process of cervical vertebra def: "An inferior articular process of vertebra that is part of a cervical vertebra." [OBOL:automatic] [Term] id: UBERON:0008463 name: inferior articular process of thoracic vertebra synonym: "caudal articular process of thoracic vertebra" EXACT [FMA:9156] synonym: "inferior apophyseal process" EXACT [FMA:9156] synonym: "inferior zygapophysis" EXACT [FMA:9156] synonym: "processus articularis (zygapophysis) thoracicus inferior" EXACT [FMA:9156] intersection_of: UBERON:0001080 ! inferior articular process of vertebra intersection_of: part_of UBERON:0002347 ! thoracic vertebra xref: FMA:9156 ! inferior articular process of thoracic vertebra xref: SCTID:367814007 ! Entire inferior articular process of thoracic vertebra def: "An inferior articular process of vertebra that is part of a thoracic vertebra." [OBOL:automatic] [Term] id: UBERON:0001132 name: parathyroid gland def: "The parathyroid gland is an organ specialised for secretion of parathyroid hormone[GO]. Parathyroid glands control the amount of calcium in the blood and within the bones[WP]." [Wikipedia:Parathyroid_gland] comment: Development notes: table 13.1 of Kardong is used to create the taxon-specific developmental relationships here, although some omissions are made for simplicity. Additional notes: Parathyroid glands are found in all adult tetrapods, although they vary in their number, and in their exact position. Mammals typically have four parathyroids, while other groups typically have six. Fish do not possess parathyroid glands, although the ultimobranchial glands, which are found close to the oesophagus, may have a similar function and could even be homologous with the tetrapod parathyroids. Even these glands are absent in the most primitive vertebrates, the jawless fish, but as these species have no bone in their skeletons, only cartilage, it may be that they have less need to regulate calcium metabolism. The conserved homology of genes and calcium-sensing receptors in fish gills with those in the parathryroid glands of birds and mammals is recognized by evolutionary developmental biology as evolution-using genes and gene networks in novel ways to generate new structures with some similar functions and novel functions[WP]. The parathryoid gland is not formed in fish, but is only found in tetrapods. In humans and chick it emerges from pouches 3 and 4, but in mice it is exclusively generated by the third pouch[PMID:16313389] subset: uberon_slim synonym: "parathyroid" EXACT [] synonym: "parathyroid secreting cell" RELATED [] xref: BTO:0000997 xref: EFO:0000862 ! parathyroid xref: FMA:13890 ! Parathyroid gland xref: GAID:452 ! parathyroid gland xref: VHOG:0001188 ! parathyroid gland xref: MA:0000128 ! parathyroid gland xref: MAT:0000082 ! parathyroid xref: MIAA:0000082 ! parathyroid xref: XAO:0000167 ! parathyroid xref: ncithesaurus:Parathyroid_Gland ! Parathyroid Gland xref: MESH:A06.407.560 ! parathyroid gland xref: EV:0100134 ! parathyroid is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0000949 ! endocrine system relationship: has_function_in GO:0055074 {source="Wikipedia"} ! calcium ion homeostasis relationship: capable_of GO:0035898 ! parathyroid hormone secretion relationship: only_in_taxon NCBITaxon:32523 {source="PMID:16313389"} ! Tetrapoda relationship: has_developmental_contribution_from UBERON:0010026 {gci_relation="part_of", gci_filler="NCBITaxon:8293", notes="Urodele", source="ISBN10:0073040584-table13.1"} ! ventral part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010028 {gci_relation="part_of", gci_filler="NCBITaxon:8293", notes="Urodele", source="ISBN10:0073040584-table13.1"} ! ventral part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010026 {gci_relation="part_of", gci_filler="NCBITaxon:8342", notes="Anurans", source="ISBN10:0073040584-table13.1", source="XAO"} ! ventral part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010028 {gci_relation="part_of", gci_filler="NCBITaxon:8342", notes="Anurans", source="ISBN10:0073040584-table13.1"} ! ventral part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010026 {gci_relation="part_of", gci_filler="NCBITaxon:8782", notes="Aves", source="ISBN10:0073040584-table13.1"} ! ventral part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010028 {gci_relation="part_of", gci_filler="NCBITaxon:8782", notes="Aves", source="ISBN10:0073040584-table13.1"} ! ventral part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010025 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="Mammals", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010027 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="Mammals", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 4 relationship: develops_from UBERON:0007124 {source="PMID:16313389", gci_relation="part_of", gci_filler="NCBITaxon:10090", source="PMID:16313389"} ! pharyngeal pouch 3 relationship: develops_from UBERON:0007125 {source="PMID:16313389", gci_relation="part_of", gci_filler="NCBITaxon:9030", notes="pouches 3 and 4 in chick"} ! pharyngeal pouch 4 relationship: develops_from UBERON:0007125 {source="PMID:16313389", gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="pouches 3 and 4 in human"} ! pharyngeal pouch 4 relationship: homologous_to ZFA:0001200 {source="ZFA:0001200"} ! corpuscles of Stannius xref: AAO:0010545 ! parathyroid gland xref: SCTID:181121007 ! Entire parathyroid gland subset: organ_slim property_value: external_definition "Either of the two pairs of small, spherical, encapsulated glands which develop from ventral growths of the third and fourth pharyngeal pouches and are closely associated with the external jugular veins. Calcitonin and parathyroid hormone are secreted by these glands.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010545", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Any one of several small structures, usually four, attached to the dorsal surfaces of the lateral lobes of the thyroid gland. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001188", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/parathyroid+gland", source="http://bgee.unil.ch/"} property_value: homology_notes "The evolution of the tetrapods, and the shift from an aquatic to a terrestrial environment, was believed to have required new controls for regulating calcium homeostasis, and thus the evolution of parathyroid glands (...) both the tetrapod parathyroid and the gills of fish contribute to the regulation of extracellular calcium levels. It is therefore reasonable to suggest that the parathyroid gland evolved as a result of the transformation of the gills into the parathyroid glands of tetrapods and the transition from an aquatic to a terrestrial environment. This interpretation would also explain the positioning of the parathyroid gland within the pharynx in the tetrapod body. Were the parathyroid gland to have emerged de novo with the evolution of the tetrapods it could, as an endocrine organ, have been placed anywhere in the body and still exert its effect.[well established][VHOG]" xsd:string {external_class="VHOG:0001188", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M\, Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0030518 [Term] id: UBERON:0006749 name: superior parathyroid gland comment: Taxon notes: Mammals typically have four parathyroids, while other groups typically have six xref: FMA:55558 ! superior parathyroid gland xref: EHDAA:3870 ! superior parathyroid xref: EHDAA:9135 ! superior parathyroid xref: EHDAA2:0001954 ! superior parathyroid is_a: UBERON:0001132 ! parathyroid gland relationship: has_developmental_contribution_from UBERON:0010027 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="EHDAA2-modified"} ! dorsal part of pharyngeal pouch 4 xref: ncithesaurus:Superior_Parathyroid_Gland ! Superior Parathyroid Gland xref: SCTID:245540001 ! Superior parathyroid gland subset: organ_slim relationship: in_lateral_side_of UBERON:0000949 {source="FMA-abduced-lr"} ! endocrine system xref: UMLS:C0447651 [Term] id: UBERON:0006755 name: inferior parathyroid gland comment: Taxon notes: Mammals typically have four parathyroids, while other groups typically have six xref: FMA:55559 ! inferior parathyroid gland xref: EHDAA:3864 ! inferior parathyroid xref: EHDAA:9127 ! inferior parathyroid xref: EHDAA2:0000821 ! inferior parathyroid is_a: UBERON:0001132 ! parathyroid gland relationship: develops_from UBERON:0007124 {source="http://emedicine.medscape.com/article/845125-overview"} ! pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010025 {source="EHDAA2", notes="epithelium"} ! dorsal part of pharyngeal pouch 3 xref: ncithesaurus:Inferior_Parathyroid_Gland ! Inferior Parathyroid Gland xref: SCTID:245542009 ! Inferior parathyroid gland subset: organ_slim relationship: in_lateral_side_of UBERON:0000949 {source="FMA-abduced-lr"} ! endocrine system xref: UMLS:C0447650 [Term] id: UBERON:0011197 name: parathyroid epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001132 ! parathyroid gland is_a: UBERON:0000486 {source="EHDAA2-abduced"} ! multilaminar epithelium relationship: develops_from UBERON:0004117 ! pharyngeal pouch relationship: composed_primarily_of CL:0002260 ! epithelial cell of parathyroid gland xref: ncithesaurus:Parathyroid_Gland_Epithelial_Tissue def: "An epithelium that is part of a parathyroid gland." [OBOL:automatic] xref: UMLS:C1709466 xref: CALOHA:TS-2141 ! Parathyroid epithelium [Term] id: UBERON:0011195 name: inferior parathyroid epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006755 ! inferior parathyroid gland relationship: develops_from UBERON:0010025 {source="EHDAA2"} ! dorsal part of pharyngeal pouch 3 xref: EHDAA2:0000824 ! inferior parathyroid epithelium xref: EHDAA:3868 ! endodermal epithelium def: "An epithelium that is part of a inferior parathyroid gland." [OBOL:automatic] [Term] id: UBERON:0011196 name: superior parathyroid epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006749 ! superior parathyroid gland relationship: develops_from UBERON:0007125 {source="EHDAA2"} ! pharyngeal pouch 4 xref: EHDAA2:0001957 ! superior parathyroid epithelium xref: EHDAA:3874 ! endodermal epithelium def: "An epithelium that is part of a superior parathyroid gland." [OBOL:automatic] [Term] id: UBERON:0008242 name: lower back muscle xref: MA:0000502 ! lower back muscle is_a: UBERON:0003833 {source="MA"} ! abdominal segment muscle intersection_of: UBERON:0002324 ! muscle of back intersection_of: part_of UBERON:0005462 ! lumbar region relationship: part_of UBERON:0005462 {source="MA"} ! lumbar region xref: SCTID:317178000 ! Entire muscle of lower back def: "A muscle of back that is part of a lower back." [OBOL:automatic] [Term] id: UBERON:0008243 name: upper back muscle xref: MA:0000508 ! upper back muscle is_a: UBERON:0003830 {source="MA"} ! thoracic segment muscle intersection_of: UBERON:0002324 ! muscle of back intersection_of: part_of UBERON:0008231 ! dorsal thoracic segment of trunk relationship: part_of UBERON:0008231 {source="MA"} ! dorsal thoracic segment of trunk xref: SCTID:305071003 ! Entire muscle of upper back def: "A muscle of back that is part of a dorsal thoracic segment of trunk." [OBOL:automatic] [Term] id: UBERON:0005617 ! mesenteric vein name: mesenteric vein def: "Veins which return blood from the intestines; the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein." [MESH:A07.231.908.670.385, Wikipedia:Mesenteric_vein] xref: MA:0002177 ! mesenteric vein xref: RETIRED_EHDAA2:0001125 ! mesenteric vein xref: BTO:0002781 ! mesenteric vein xref: EMAPA:17348 ! mesenteric vein xref: MESH:A07.231.908.670.385 ! mesenteric vein xref: EHDAA:4442 ! mesenteric vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0005806 ! portal system xref: ncithesaurus:Mesenteric_Vein ! Mesenteric Vein xref: SCTID:304045008 ! Entire mesenteric vein xref: UMLS:C0025473 [Term] id: UBERON:0001138 name: superior mesenteric vein def: "In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Superior_mesenteric_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "upper mesenteric vein" RELATED [BTO:0002783] xref: EHDAA:5414 ! superior mesenteric vein xref: FMA:14332 ! Superior mesenteric vein xref: VHOG:0000552 ! superior mesenteric vein xref: MA:0002179 ! superior mesenteric vein xref: ncithesaurus:Superior_Mesenteric_Vein ! Superior Mesenteric Vein xref: BTO:0002783 ! superior mesenteric vein xref: OpenCyc:Mx4rwFjmM5wpEbGdrcN5Y29ycA ! superior mesenteric vein xref: EHDAA2:0001951 ! superior mesenteric vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Gray591.png/200px-Gray591.png xref: EMAPA:18643 ! superior of mesenteric vein is_a: UBERON:0005617 ! mesenteric vein relationship: develops_from UBERON:0005487 {source="Wikipedia:Vitelline_vein"} ! vitelline vein xref: SCTID:278031001 ! Entire superior mesenteric vein synonym: "vena mesenterica superior" RELATED LATIN [Wikipedia:Superior_mesenteric_vein] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png xref: UMLS:C0226742 [Term] id: UBERON:0001215 name: inferior mesenteric vein def: "In human anatomy, the inferior mesenteric vein (IMV) is a blood vessel that drains blood from the large intestine. It usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Inferior_mesenteric_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lower mesenteric vein" RELATED [BTO:0002782] xref: EHDAA:8712 ! inferior mesenteric vein xref: FMA:15391 ! Inferior mesenteric vein xref: VHOG:0001118 ! inferior mesenteric vein xref: MA:0002178 ! inferior mesenteric vein xref: OpenCyc:Mx4rvcV53ZwpEbGdrcN5Y29ycA xref: ncithesaurus:Inferior_Mesenteric_Vein ! Inferior Mesenteric Vein xref: BTO:0002782 ! inferior mesenteric vein xref: OpenCyc:Mx4rvcV53ZwpEbGdrcN5Y29ycA ! inferior mesenteric vein xref: EHDAA2:0000819 ! inferior mesenteric vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Gray591.png/200px-Gray591.png xref: EMAPA:18642 ! inferior of mesenteric vein is_a: UBERON:0005617 ! mesenteric vein relationship: tributary_of UBERON:0003713 {source="FMA/obol"} ! splenic vein xref: SCTID:281055007 ! Entire inferior mesenteric vein synonym: "vena mesenterica inferior" RELATED LATIN [Wikipedia:Inferior_mesenteric_vein] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png xref: UMLS:C0226754 [Term] id: UBERON:0001139 name: common iliac vein def: "In human anatomy, the common iliac veins are formed by the external iliac veins and internal iliac veins and together, in the abdomen at the level of the fifth lumbar vertebrae, form the inferior vena cava. They drain blood from the pelvis and lower limbs. Both common iliac veins are accompanied along their course by common iliac arteries. [WP,unvetted]." [Wikipedia:Common_iliac_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "common iliac venous tree" EXACT [] xref: FMA:14333 ! Common iliac vein xref: galen:CommonIliacVein xref: MA:0002143 ! common iliac vein xref: OpenCyc:Mx4rv92CGZwpEbGdrcN5Y29ycA xref: ncithesaurus:Common_Iliac_Vein ! Common Iliac Vein xref: OpenCyc:Mx4rv92CGZwpEbGdrcN5Y29ycA ! common iliac vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Iliac_veins.gif/200px-Iliac_veins.gif xref: EMAPA:17874 ! common iliac vein is_a: UBERON:0001638 ! vein xref: SCTID:181398004 ! Entire common iliac vein synonym: "vena iliaca communis" RELATED LATIN [Wikipedia:Common_iliac_vein] xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Iliac_veins.gif relationship: in_lateral_side_of UBERON:0001072 {source="FMA-abduced-lr"} ! inferior vena cava xref: UMLS:C0226758 [Term] id: UBERON:0003920 ! venous blood vessel name: venous blood vessel def: "a blood vessel that carries blood from the capillaries toward the heart" [http://www.thefreedictionary.com/venous+blood+vessel] comment: Compare to: vein synonym: "segment of venous tree organ" EXACT [FMA:86188] synonym: "venous tree organ segment" EXACT [FMA:86188] xref: MA:0000066 ! venous blood vessel xref: FMA:86188 ! Segment of venous tree organ intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004582 ! venous system [Term] id: UBERON:0001140 name: renal vein def: "The renal veins are veins that drain the kidney. They connect the kidney to the inferior vena cava. It is usually singular to each kidney, except in the condition 'multiple renal veins'. It also divides into 2 divisions upon entering the kidney: the anterior branch which receives blood from the anterior portion of the kidney and, the posterior branch which receives blood from the posterior portion. Often, each renal vein will have a branch that receives blood from the ureter. [WP,unvetted]." [Wikipedia:Renal_vein, Wikipedia:Renal_vein] comment: AO notes: see also MA:0002591 'kidney venous blood vessel'. in EHDAA2, the renal vein is part of the kidney subset: uberon_slim synonym: "renal venous tree" EXACT [] synonym: "kidney vein" EXACT [OBOL:automatic] synonym: "vein of kidney" EXACT [OBOL:automatic] synonym: "kidney venous blood vessel" EXACT [MA:0002591] xref: EHDAA:8722 ! renal vein xref: FMA:14334 ! Renal vein xref: GAID:544 ! renal vein xref: MA:0002210 ! renal vein xref: OpenCyc:Mx4rvdUXKJwpEbGdrcN5Y29ycA xref: ncithesaurus:Renal_Vein ! Renal Vein xref: BTO:0002681 ! renal vein xref: galen:RenalVein ! renal vein xref: OpenCyc:Mx4rvdUXKJwpEbGdrcN5Y29ycA ! renal vein xref: EHDAA2:0001602 ! renal vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/76/Gray1122.png/200px-Gray1122.png xref: EMAPA:19223 ! renal vein of large blood vessels xref: EMAPA:28376 ! renal vein of renal vasculature xref: MESH:A07.231.908.752 ! renal vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002113 ! kidney relationship: tributary_of UBERON:0001072 ! inferior vena cava xref: SCTID:116358006 ! Vein of kidney synonym: "venae renales" RELATED LATIN [Wikipedia:Renal_vein] xref: http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1122.png xref: UMLS:C0035092 [Term] id: UBERON:0001141 name: right renal vein comment: This class was created automatically from a combination of ontologies xref: FMA:14335 ! Right renal vein xref: MA:0002212 ! right renal vein xref: ncithesaurus:Right_Renal_Vein ! Right Renal Vein xref: OpenCyc:Mx8Ngh4rvgHsHZwpEbGdrcN5Y29ycB4rvdUXKJwpEbGdrcN5Y29ycA ! right renal vein is_a: UBERON:0001140 ! renal vein xref: SCTID:116357001 ! Entire right renal vein xref: UMLS:C0508000 [Term] id: UBERON:0001142 name: left renal vein def: "The renal veins are veins that drain the kidney. They connect the kidney to the inferior vena cava. It is usually singular to each kidney, except in the condition 'multiple renal veins'. It also divides into 2 divisions upon entering the kidney: the anterior branch which receives blood from the anterior portion of the kidney and, the posterior branch which receives blood from the posterior portion. Often, each renal vein will have a branch that receives blood from the ureter. [WP,unvetted]." [Wikipedia:Left_renal_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:14336 ! Left renal vein xref: MA:0002211 ! left renal vein xref: ncithesaurus:Left_Renal_Vein ! Left Renal Vein xref: OpenCyc:Mx8Ngh4rvgIFoJwpEbGdrcN5Y29ycB4rvdUXKJwpEbGdrcN5Y29ycA ! left renal veins xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/76/Gray1122.png/200px-Gray1122.png is_a: UBERON:0001140 ! renal vein xref: SCTID:116356005 ! Entire left renal vein xref: UMLS:C0508001 [Term] id: UBERON:0001143 name: hepatic vein def: "Vein that carries blood away from the liver[ZFA]." [ZFA:0000670, Wikipedia:Hepatic_vein, https://sourceforge.net/tracker/?func=detail&aid=3565355&group_id=76834&atid=1205376] comment: Definition derived from ZFA but general enough for other species. subset: uberon_slim subset: vertebrate_core synonym: "hepatic veins" RELATED PLURAL [] synonym: "vena hepatica" EXACT LATIN [] synonym: "liver vein" EXACT [OBOL:automatic] synonym: "vein of liver" EXACT [OBOL:automatic] xref: MA:0003015 ! hepatic vein xref: FMA:14337 ! Hepatic vein xref: GAID:534 ! hepatic vein xref: galen:HepaticVein xref: OpenCyc:Mx4rv5GivJwpEbGdrcN5Y29ycA xref: TAO:0000670 ! hepatic vein xref: XAO:0000387 ! hepatic vein xref: ZFA:0000670 ! hepatic vein xref: ncithesaurus:Hepatic_Vein ! Hepatic Vein xref: OpenCyc:Mx4rv5GivJwpEbGdrcN5Y29ycA ! hepatic vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/61/Gray1121.png/200px-Gray1121.png xref: EMAPA:19221 ! hepatic vein xref: MESH:A07.231.908.380 ! hepatic vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: channels_from UBERON:0002107 ! liver relationship: part_of UBERON:0006877 ! vasculature of liver relationship: develops_from UBERON:0005487 {source="Wikipedia:Vitelline_vein"} ! vitelline vein relationship: tributary_of UBERON:0001072 {source="FMA-abduced-lr"} ! inferior vena cava disjoint_from: UBERON:0001639 ! hepatic portal vein xref: AAO:0010216 ! hepatic vein xref: SCTID:278191001 ! Entire hepatic vein synonym: "venae hepaticae" RELATED LATIN [Wikipedia:Hepatic_vein] xref: http://upload.wikimedia.org/wikipedia/commons/6/61/Gray1121.png xref: UMLS:C0019155 [Term] id: UBERON:0011955 name: left hepatic vein intersection_of: UBERON:0001143 ! hepatic vein intersection_of: part_of UBERON:0001115 ! left lobe of liver xref: FMA:14339 ! left hepatic vein xref: SCTID:55188000 ! Entire left hepatic vein def: "A hepatic vein that is part of a left lobe of liver." [OBOL:automatic] [Term] id: UBERON:0011956 name: right hepatic vein intersection_of: UBERON:0001143 ! hepatic vein intersection_of: part_of UBERON:0001114 ! right lobe of liver xref: FMA:14338 ! right hepatic vein xref: SCTID:18135006 ! Entire right hepatic vein def: "A hepatic vein that is part of a right lobe of liver." [OBOL:automatic] [Term] id: UBERON:0011957 name: middle hepatic vein is_a: UBERON:0001143 ! hepatic vein xref: FMA:14340 ! middle hepatic vein xref: SCTID:54895000 ! Entire middle hepatic vein [Term] id: UBERON:0001144 name: testicular vein def: "The testicular vein (or spermatic vein), the male gonadal vein, carries deoxygenated blood from its corresponding testis to the inferior vena cava or one of its tributaries. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis: the right testicular vein generally joins the inferior vena cava; the left testicular vein, unlike the right, often joins the left renal vein instead of the inferior vena cava. The veins emerge from the back of the testis, and receive tributaries from the epididymis; they unite and form a convoluted plexus, called the pampiniform plexus, which constitutes the greater mass of the spermatic cord; the vessels composing this plexus are very numerous, and ascend along the cord, in front of the ductus deferens. Below the subcutaneous inguinal ring, they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins, which ascend on the Psoas major, behind the peritoneum, lying one on either side of the internal spermatic artery. These unite to form a single vein, which opens, on the right side, into the inferior vena cava (at an acute angle), on the left side into the left renal vein (at a right angle). The spermatic veins are provided with valves. The left spermatic vein passes behind the iliac colon and is thus exposed to pressure from the contents of that part of the bowel. [WP,unvetted]." [Wikipedia:Testicular_vein, https://sourceforge.net/tracker/?func=detail&aid=3220553&group_id=76834&atid=1205376] comment: Comment: todo - check testicular vs spermatic vein (MA:0002218) subset: uberon_slim synonym: "testicular venous tree" EXACT [Wikipedia:Testicular_vein] synonym: "male gonadal vein" EXACT [Wikipedia:Testicular_vein] synonym: "spermatic vein" EXACT [Wikipedia:Testicular_vein] synonym: "testicle vein" EXACT [OBOL:automatic] synonym: "vein of testicle" EXACT [OBOL:automatic] synonym: "vena tesicularis" RELATED [BTO:0002678] xref: FMA:14344 ! Testicular vein xref: MA:0002234 ! testicular vein xref: MA:0002218 ! spermatic vein xref: OpenCyc:Mx4rv1WIHpwpEbGdrcN5Y29ycA xref: BTO:0002678 ! testicular vein xref: OpenCyc:Mx4rv1WIHpwpEbGdrcN5Y29ycA ! testicular vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/Gray590.png/200px-Gray590.png xref: EMAPA:18647 ! testicular vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: connected_to UBERON:0000473 ! testicle relationship: connected_to UBERON:0001072 ! inferior vena cava relationship: connected_to UBERON:0001330 ! pampiniform plexus relationship: sexually_homologous_to UBERON:0001145 ! ovarian vein relationship: in_lateral_side_of UBERON:0000468 ! multi-cellular organism xref: ncithesaurus:Spermatic_Vein ! Spermatic Vein xref: SCTID:264496006 ! Entire testicular vein synonym: "vena testicularis sinistra," RELATED LATIN [Wikipedia:Testicular_vein] synonym: "venae spermaticae" RELATED LATIN [Wikipedia:Testicular_vein] synonym: "vena testicularis dextra," RELATED LATIN [Wikipedia:Testicular_vein] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/Gray590.png xref: UMLS:C0226718 [Term] id: UBERON:0000442 name: right testicular vein def: "A vein that drains the left pampiniform plexus and empties into the left renal vein." [Dorlands_Medical_Dictionary:MerckSource] synonym: "vena testicularis sinistra" RELATED [BTO:0002680] synonym: "vena testicularis (adrenalis) dextra" EXACT [FMA:14341] synonym: "vena testicularis dextra" RELATED [BTO:0002679] xref: BTO:0002679 xref: FMA:14341 ! Right testicular vein xref: MA:0002220 ! right spermatic vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: connected_to UBERON:0004534 ! right testicle relationship: connected_to UBERON:0001142 ! left renal vein relationship: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:53500001 ! Entire right testicular vein synonym: "right spermatic vein" EXACT [MA:0002220] [Term] id: UBERON:0000443 name: left testicular vein def: "A vein that drains the right pampiniform plexus and empties into the inferior vena cava." [Dorlands_Medical_Dictionary:MerckSource] synonym: "vena testicularis dextra" RELATED [BTO:0002679] synonym: "vena testicularis sinistra" RELATED [BTO:0002680] xref: BTO:0002680 xref: FMA:14345 ! Left testicular vein xref: MA:0002219 ! left spermatic vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: connected_to UBERON:0004533 ! left testicle relationship: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:90988008 ! Entire left testicular vein synonym: "left spermatic vein" EXACT [MA:0002219] [Term] id: UBERON:0001145 name: ovarian vein def: "The ovarian vein, the female gonadal vein, carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries. It is the female equivalent of the testicular vein, and is the venous counterpart of the ovarian artery. It can be found in the suspensory ligament of the ovary. It a paired vein, with one supplying each ovary. The right ovarian vein travels through the suspensatory ligament of the ovary and generally joins the inferior vena cava. The left ovarian vein, unlike the right, often joins the left renal vein instead of the inferior vena cava. [WP,unvetted]." [Wikipedia:Ovarian_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "ovary vein" EXACT [OBOL:automatic] synonym: "vein of ovary" EXACT [OBOL:automatic] synonym: "female reproductive system gonad vein" EXACT [OBOL:automatic] synonym: "female reproductive system gonada vein" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system vein" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system vein" EXACT [OBOL:automatic] synonym: "vein of female reproductive system gonad" EXACT [OBOL:automatic] synonym: "vein of female reproductive system gonada" EXACT [OBOL:automatic] synonym: "vein of gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "vein of gonada of female reproductive system" EXACT [OBOL:automatic] xref: FMA:14346 ! Ovarian vein xref: MA:0002186 ! ovarian vein xref: ncithesaurus:Ovarian_Vein ! Ovarian Vein xref: OpenCyc:Mx4rvrST5ZwpEbGdrcN5Y29ycA ! ovarian vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Ovarschaf.jpg/200px-Ovarschaf.jpg xref: EMAPA:18644 ! ovarian vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: connected_to UBERON:0000992 ! female gonad relationship: in_lateral_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:278193003 ! Entire ovarian vein synonym: "vena ovarica sinistra, vena ovarica dextra" RELATED LATIN [Wikipedia:Ovarian_vein] xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Ovarschaf.jpg xref: UMLS:C0226720 [Term] id: UBERON:0001146 name: suprarenal vein def: "The Suprarenal veins are two in number: the right ends in the inferior vena cava. the left ends in the left renal or left inferior phrenic vein. They receive blood from the adrenal glands and will sometimes form anastomoses with the inferior phrenic veins. [WP,unvetted]." [Wikipedia:Suprarenal_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: EHDAA:8731 ! suprarenal vein xref: FMA:14348 ! Suprarenal vein xref: MA:0002229 ! suprarenal vein xref: ncithesaurus:Suprarenal_Vein ! Suprarenal Vein xref: EHDAA2:0001966 ! suprarenal vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/76/Gray1122.png/200px-Gray1122.png is_a: UBERON:0001638 ! vein xref: SCTID:278194009 ! Entire suprarenal vein xref: UMLS:C0226717 [Term] id: UBERON:0001147 name: trunk of peripheral nerve comment: This class was created automatically from a combination of ontologies subset: non_informative subset: grouping_class synonym: "peripheral nerve trunk" EXACT [] synonym: "peripheral neural trunk" EXACT [] xref: FMA:14383 ! Trunk of peripheral nerve xref: MA:0000229 ! peripheral nerve trunk xref: EMAPA:16986 ! nerve trunk (also: UBERON:0002464 'nerve trunk') (also: UBERON:0003439 'nerve of trunk region') (also: UBERON:0004295 'sympathetic nerve trunk') is_a: UBERON:0002464 ! nerve trunk relationship: part_of UBERON:0002003 ! peripheral nerve [Term] id: UBERON:0001148 name: median nerve def: "The median nerve is a nerve in humans and other animals. It is in the upper limb. It is one of the five main nerves originating from the brachial plexus. The median nerve is formed from parts of the medial and lateral cords of the brachial plexus, and continues down the arm to enter the forearm with the brachial artery. It originates from the brachial plexus with roots from C5, C6, C7, C8 & T1. The median nerve is the only nerve that passes through the carpal tunnel, where it may be compressed to cause carpal tunnel syndrome. [WP,unvetted]." [Wikipedia:Median_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: EHDAA:5648 ! median nerve xref: FMA:14385 ! Median nerve xref: GAID:843 ! median nerve xref: MA:0001168 ! median nerve xref: ncithesaurus:Median_Nerve ! Median Nerve xref: OpenCyc:Mx4rwF4HF5wpEbGdrcN5Y29ycA ! median nerve xref: EHDAA2:0001086 ! median nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Nerves_of_the_left_upper_extremity.gif/200px-Nerves_of_the_left_upper_extremity.gif xref: EMAPA:17277 ! median nerve xref: MESH:A08.800.800.720.050.500 ! median nerve is_a: UBERON:0002003 ! peripheral nerve relationship: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001814 ! brachial nerve plexus xref: SCTID:181010001 ! Entire median nerve synonym: "nervus medianus" RELATED LATIN [Wikipedia:Median_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/a/a7/Nerves_of_the_left_upper_extremity.gif xref: UMLS:C0025058 [Term] id: UBERON:0001149 name: bare area of liver comment: This class was created automatically from a combination of ontologies synonym: "area nuda (hepar)" EXACT [] synonym: "area nuda hepatis" EXACT [] synonym: "liver bare area" EXACT [] xref: FMA:14480 ! Bare area of liver xref: MA:0000359 ! liver bare area xref: EMAPA:17945 ! bare area of liver xref: EMAPA:18308 ! bare area of left of lobe of liver xref: EMAPA:18312 ! bare area of right of lobe of liver is_a: UBERON:0000466 ! immaterial anatomical entity relationship: part_of UBERON:0001114 ! right lobe of liver xref: SCTID:279965008 ! Entire area nuda hepatis [Term] id: UBERON:0001150 name: body of pancreas def: "The body of the pancreas is a subsection of the pancreas organ in the human body. It is somewhat prismatic in shape, and has three surfaces: anterior, posterior, and inferior. It is at the same level as the transpyloric plane. [WP,unvetted]." [Wikipedia:Body_of_pancreas] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "pancreas body" EXACT [] synonym: "pancreas corpus" RELATED [] synonym: "pancreatic body" EXACT [] xref: FMA:14518 ! Body of pancreas xref: VHOG:0000451 ! pancreas body xref: MA:0000121 ! pancreas body xref: EHDAA2:0001368 ! pancreas body xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Illu_pancreas_duodenum.jpg/200px-Illu_pancreas_duodenum.jpg xref: EMAPA:17504 ! body of pancreas of gland of foregut-midgut junction xref: EMAPA:18817 ! body of pancreas of gland of gut xref: EHDAA:9178 ! body (also: UBERON:0000468 'multi-cellular organism') is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001264 ! pancreas xref: ncithesaurus:Body_of_the_Pancreas ! Body of the Pancreas xref: SCTID:362202004 ! Entire body of pancreas synonym: "corpus pancreatis" RELATED LATIN [Wikipedia:Body_of_pancreas] xref: http://upload.wikimedia.org/wikipedia/commons/f/fe/Illu_pancreas_duodenum.jpg property_value: homology_notes "Hagfish and lampreys may have one or more endocrine buds - and later the vertebrate pancreas develop as independent ventral and dorsal buds that eventually fuse to become one organ.[well established][VHOG]" xsd:string {external_class="VHOG:0000451", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD\, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. Comptes Rendus Biologies (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0227582 [Term] id: UBERON:0001151 name: tail of pancreas def: "The tail of the pancreas, located anatomically left near the hilum of the spleen, is not simply an anatomical distinction. The tail is the only part of the pancreas which contains Pancreatic Polypeptide (PP) cells, which are responsible for secreting pancreatic polypeptide to coordinate exocrine and islet enzyme release. PP cells are found in the tail's periphery. Beta cells and delta cells are found in the central part of the tail as with the rest of the pancreas. The cells described above are located exclusively in the islet cells; their secretions reach exocrine portions of the pancreas via the capillary network surrounding the islet cell populations. [WP,unvetted]." [Wikipedia:Tail_of_pancreas] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "left extremity of pancreas" EXACT [FMA:14519] synonym: "pancreatic tail" EXACT [FMA:14519] synonym: "pancreas tail" EXACT [] xref: FMA:14519 ! Tail of pancreas xref: VHOG:0000452 ! pancreas tail xref: MA:0000123 ! pancreas tail xref: EHDAA2:0001390 ! pancreas tail xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Illu_pancreas_duodenum.jpg/200px-Illu_pancreas_duodenum.jpg xref: EMAPA:17511 ! tail of pancreas of gland of foregut-midgut junction xref: EMAPA:18824 ! tail of pancreas of gland of gut is_a: UBERON:0000064 ! organ part relationship: develops_from UBERON:0009708 {source="EHDAA2"} ! dorsal pancreas relationship: part_of UBERON:0001264 {source="FMA"} ! pancreas xref: ncithesaurus:Tail_of_the_Pancreas ! Tail of the Pancreas xref: SCTID:245382003 ! Entire tail of pancreas synonym: "cauda pancreatis" RELATED LATIN [Wikipedia:Tail_of_pancreas] xref: http://upload.wikimedia.org/wikipedia/commons/f/fe/Illu_pancreas_duodenum.jpg property_value: homology_notes "Hagfish and lampreys may have one or more endocrine buds - and later the vertebrate pancreas develop as independent ventral and dorsal buds that eventually fuse to become one organ.[well established][VHOG]" xsd:string {external_class="VHOG:0000452", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD\, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. Comptes Rendus Biologies (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0227590 [Term] id: UBERON:0009854 ! digestive tract diverticulum name: digestive tract diverticulum def: "Branch or outpocketing of the digestive tract." [UBERON:cjm] is_a: UBERON:0004921 ! subdivision of digestive tract intersection_of: UBERON:0009856 ! sac intersection_of: part_of UBERON:0001555 ! digestive tract xref: FBbt:00100316 ! diverticulum of gut synonym: "diverticulum of gut" RELATED [FBbt:00100316] synonym: "intestinal pouch" RELATED [] [Term] id: UBERON:0001153 name: caecum def: "Pouch, connecting the ileum with the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve, and is the beginning of the large intestine. It is also separated from the colon by the cecocolic junction." [Wikipedia:Cecum] comment: Taxon notes: A cecum is present in most amniote species, and also in lungfish, but not in any living species of amphibian. In reptiles, it is usually a single median structure, arising from the dorsal side of the large intestine. Birds typically have two paired ceca, as, unlike other mammals, do hyraxes. Most mammalian herbivores have a relatively large cecum, hosting a large number of bacteria, which aid in the enzymatic breakdown of plant materials such as cellulose; in many species, it is considerably wider than the colon. In contrast, obligatory carnivores, whose diets contain little or no plant material, have a reduced cecum, which is often partially or wholly replaced by the vermiform appendix. Many fish have a number of small outpocketings, called pyloric ceca, along their intestine; despite the name they are not homologous with the cecum of amniotes, and their purpose is to increase the overall area of the digestive epithelium.[2] Some invertebrates, such as squid,[3] may also have structures with the same name, but these have no relationship with those of vertebrates.[WP] Kardong: in some herbivorous lizards, a cecum is present between small and large intestines subset: uberon_slim synonym: "caeca" NARROW PLURAL [NCBITaxon:8782] synonym: "ceca" NARROW PLURAL [NCBITaxon:8782] synonym: "cecum" EXACT [FMA:14541] synonym: "intestinum crassum caecum" EXACT [] synonym: "blind intestine" RELATED [BTO:0000166] synonym: "blindgut" RELATED [BTO:0000166] synonym: "intestinum caecum" RELATED [BTO:0000166] synonym: "intestinum crassum cecum" RELATED [BTO:0000166] xref: BTO:0000166 xref: FMA:14541 ! Cecum xref: GAID:307 ! cecum xref: galen:Cecum xref: MA:0000334 ! cecum xref: MIAA:0000288 ! caecum xref: ncithesaurus:Cecum xref: EFO:0000850 ! caecum xref: VHOG:0001559 ! caecum xref: EHDAA:3913 ! caecum xref: OpenCyc:Mx4rve6u4JwpEbGdrcN5Y29ycA ! caecum xref: EHDAA2:0000206 ! caecum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/82/Stomach_colon_rectum_diagram.svg/200px-Stomach_colon_rectum_diagram.svg.png xref: MESH:A03.492.411.495.209 ! cecum xref: EV:0100397 ! cecum is_a: UBERON:0009854 ! digestive tract diverticulum relationship: continuous_with UBERON:0001156 {source="Wikipedia"} ! ascending colon relationship: part_of UBERON:0001155 {source="EHDAA2"} ! colon relationship: part_of UBERON:0000059 {source="MA"} ! large intestine relationship: develops_from UBERON:0001045 {source="Wikipedia"} ! midgut relationship: never_in_taxon NCBITaxon:32443 {source="Wikipedia"} ! Teleostei relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata xref: SCTID:181256004 ! Entire cecum xref: http://upload.wikimedia.org/wikipedia/commons/8/82/Stomach_colon_rectum_diagram.svg property_value: has_relational_adjective "caecal" xsd:string xref: UMLS:C0007531 [Term] id: UBERON:0001154 name: vermiform appendix def: "a blind-ended tube connected to the cecum, from which it develops embryologically[WP]." [Wikipedia:Vermiform_appendix] subset: uberon_slim synonym: "caecal appendix" EXACT [] synonym: "cecal appendix" EXACT [] synonym: "appendix" EXACT [] synonym: "vermix" BROAD [] synonym: "appendix vermiformis" EXACT LATIN [FMA:TA, FMA:14542] synonym: "apex of cecum" RELATED [VHOG:0001306] xref: BTO:0000084 ! vermiform appendix xref: EFO:0000849 ! appendix xref: FMA:14542 ! Appendix xref: GAID:308 ! appendix xref: VHOG:0001306 ! appendix xref: MA:0001540 ! appendix xref: MAT:0000287 ! appendix xref: MIAA:0000287 ! appendix xref: ncithesaurus:Vermiform_Appendix xref: OpenCyc:Mx4rvVjGgJwpEbGdrcN5Y29ycA xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ad/Gray536.png/200px-Gray536.png xref: MESH:A03.492.411.495.209.290 ! appendix xref: EV:0100076 ! vermiform appendix xref: EV:0100080 ! appendix is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001153 {source="MA"} ! caecum relationship: part_of UBERON:0004907 {source="FMA"} ! lower digestive tract relationship: develops_from UBERON:0001045 {source="Wikipedia"} ! midgut xref: galen:AppendixVermiformis xref: SCTID:181255000 ! Entire appendix xref: EHDAA2:0000588 ! appendix subset: organ_slim synonym: "appendix vermiformis" RELATED LATIN [Wikipedia:Vermiform_appendix] xref: http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray536.png property_value: homology_notes "A comparative anatomical approach reveals three apparent morphotypes of the cecal appendix, as well as appendix-like structures in some species that lack a true cecal appendix. Cladistic analyses indicate that the appendix has evolved independently at least twice (at least once in diprotodont marsupials and at least once in Euarchontoglires), shows a highly significant (P < 0.0001) phylogenetic signal in its distribution, and has been maintained in mammalian evolution for 80 million years or longer.[well established][VHOG]" xsd:string {external_class="VHOG:0001306", ontology="VHOG", source="DOI:10.1111/j.1420-9101.2009.01809.x Smith HF\, Fisher RE\, Everett ML\, Thomas AD\, Randal Bollinger R\, Parker W\, Comparative anatomy and phylogenetic distribution of the mammalian cecal appendix. Journal of Evolutionary Biology (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "appendiceal" xsd:string xref: UMLS:C0003617 property_value: external_definition "Organ with organ cavity which is continuous proximally with the cecum and distally terminates in the tip of the appendix. Examples: There is only one appendix[FMA:14542]." xsd:string {source="FMA:14542"} [Term] id: UBERON:0001155 name: colon def: "Last portion of the digestive system in most vertebrates; it extracts water and salt from solid wastes before they are eliminated from the body[WP] In mammals, the colon consists of four sections: the ascending colon, the transverse colon, the descending colon, and the sigmoid colon[WP]. In zebrafish, the posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates. Wallace et al, 2005." [Wikipedia:Colon_(anatomy), ZFIN:curator] comment: TODO: abstract this such that it legitimately covers all vertebrates subset: uberon_slim subset: vertebrate_core synonym: "hindgut" RELATED [] synonym: "large bowel" EXACT [] synonym: "posterior intestine" NARROW [] synonym: "posterior intestine - zebrafish" BROAD [] xref: BTO:0000269 xref: EFO:0000361 ! colon xref: FMA:14543 ! Colon xref: GAID:309 ! colon xref: galen:Colon xref: VHOG:0000648 ! colon xref: MA:0000335 ! colon xref: MAP:0000001 ! colon xref: MAT:0000526 ! colon xref: ncithesaurus:Colon xref: OpenCyc:Mx4rvgLEM5wpEbGdrcN5Y29ycA xref: TAO:0000706 ! posterior intestine xref: XAO:0000243 ! colon xref: ZFA:0000706 ! posterior intestine xref: OpenCyc:Mx4rvgLEM5wpEbGdrcN5Y29ycA ! colon xref: EMAPA:18939 ! colon xref: MESH:A03.492.411.495.356 ! colon xref: EV:0100079 ! colon is_a: UBERON:0004921 {source="cjm", order="3"} ! subdivision of digestive tract relationship: part_of UBERON:0000059 {source="FMA"} ! large intestine xref: AAO:0010400 ! colon xref: SCTID:302508007 ! Entire colon property_value: external_definition "The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010400", date_retrieved="2012-06-20", source="UBERON:0001155"} property_value: external_definition "The posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates. Wallace et al, 2005.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000706", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000648", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "colonic" xsd:string xref: UMLS:C0009368 [Term] id: UBERON:0012652 ! colorectum name: colorectum def: "The colon and rectum considered as a unit." [BTO:0001613] is_a: UBERON:0004921 {source="cjm", order="non-canonical"} ! subdivision of digestive tract relationship: part_of UBERON:0000059 ! large intestine xref: BTO:0001613 ! colorectum xref: ncithesaurus:Colorectal_Region ! colorectal region property_value: has_relational_adjective "colorectal" xsd:string xref: UMLS:C1711309 xref: CALOHA:TS-1298 ! Colorectum [Term] id: UBERON:0001156 name: ascending colon def: "Organ part which is continuous with the cecum proximally and the transverse colon distally.[FMA]" [Wikipedia:Ascending_colon, FMA:FMA] comment: Note that in MA, this is a subclass of colon subset: uberon_slim xref: EFO:0000843 ! ascending colon xref: FMA:14545 ! Ascending colon xref: galen:AscendingColon xref: MA:0001541 ! ascending colon xref: MAT:0000311 ! ascending colon xref: MIAA:0000311 ! ascending colon xref: ncithesaurus:Ascending_Colon xref: OpenCyc:Mx4rv3H0FZwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rv3H0FZwpEbGdrcN5Y29ycA ! ascending colon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3b/Dickdarm-Schema.svg/200px-Dickdarm-Schema.svg.png xref: BTO:0000270 ! colon ascendens is_a: UBERON:0000168 {source="FMA"} ! segment of colon relationship: continuous_with UBERON:0001157 ! transverse colon relationship: develops_from UBERON:0001045 {source="Wikipedia"} ! midgut xref: SCTID:362162009 ! Entire ascending colon synonym: "colon ascendens" RELATED LATIN [Wikipedia:Ascending_colon] synonym: "spiral colon" RELATED SENSU [Wikipedia:Spiral_colon] xref: http://upload.wikimedia.org/wikipedia/commons/3/3b/Dickdarm-Schema.svg xref: UMLS:C0227375 [Term] id: UBERON:0010239 name: spiral colon def: "A variant of the ascending colon in ruminants and pigs." [Wikipedia:Spiral_colon] comment: Editor notes: Consider merging with ascending colon synonym: "coiled colon" EXACT [] is_a: UBERON:0000168 ! segment of colon relationship: continuous_with UBERON:0001157 ! transverse colon relationship: develops_from UBERON:0001045 {source="Wikipedia"} ! midgut relationship: homologous_to UBERON:0001156 ! ascending colon xref: ncithesaurus:Spiral_Colon xref: UMLS:C0227374 [Term] id: UBERON:0001157 name: transverse colon def: "The transverse colon the longest and most movable part of the colon, passes with a downward convexity from the right hypochondrium region across the abdomen, opposite the confines of the epigastric and umbilical zones, into the left hypochondrium region, where it curves sharply on itself beneath the lower end of the spleen, forming the splenic or left colic flexure. The right colic flexure is adjacent to the liver. In its course, it describes an arch, the concavity of which is directed backward and a little upward; toward its splenic end there is often an abrupt U-shaped curve which may descend lower than the main curve. It is almost completely invested by peritoneum, and is connected to the inferior border of the pancreas by a large and wide duplicature of that membrane, the transverse mesocolon. It is in relation, by its upper surface, with the liver and gall-bladder, the greater curvature of the stomach, and the lower end of the spleen; by its under surface, with the small intestine; by its anterior surface, with the anterior layers of the greater omentum and the abdominal parietes; its posterior surface is in relation from right to left with the descending portion of the duodenum, the head of the pancreas, and some of the convolutions of the jejunum and ileum. [WP,unvetted]." [Wikipedia:Transverse_colon] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: EFO:0000844 ! transverse colon xref: FMA:14546 ! Transverse colon xref: MA:0001543 ! transverse colon xref: MAT:0000312 ! transverse colon xref: MIAA:0000312 ! transverse colon xref: ncithesaurus:Transverse_Colon xref: OpenCyc:Mx4rvg7qyJwpEbGdrcN5Y29ycA xref: galen:TransverseColon ! transverse colon xref: OpenCyc:Mx4rvg7qyJwpEbGdrcN5Y29ycA ! transverse colon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3b/Dickdarm-Schema.svg/200px-Dickdarm-Schema.svg.png xref: BTO:0000272 ! colon transversum is_a: UBERON:0000168 {source="FMA"} ! segment of colon relationship: continuous_with UBERON:0001158 ! descending colon relationship: develops_from UBERON:0001045 {source="Wikipedia"} ! midgut xref: SCTID:362163004 ! Entire transverse colon synonym: "colon transversum" RELATED LATIN [Wikipedia:Transverse_colon] xref: http://upload.wikimedia.org/wikipedia/commons/3/3b/Dickdarm-Schema.svg xref: UMLS:C0227386 [Term] id: UBERON:0001158 name: descending colon def: "The descending colon of humans passes downward through the left hypochondrium and lumbar regions, along the lateral border of the left kidney. At the lower end of the kidney it turns medialward toward the lateral border of the psoas muscle, and then descends, in the angle between psoas and quadratus lumborum, to the crest of the ilium, where it ends in the sigmoid colon. The peritoneum covers its anterior surface and sides, and therefore the descending colon is described as retroperitoneal. (The transverse colon and sigmoid colon, which are immediately proximal and distal, are intraperitoneal). Its posterior surface is connected by areolar tissue with the lower and lateral part of the left kidney, the aponeurotic origin of the transversus abdominis, and the quadratus lumborum. It is smaller in caliber and more deeply placed than the ascending colon. It has a mesentery in 33% of people, and is therefore more frequently covered with peritoneum on its posterior surface than the ascending colon (which has a mesentery in 25% of people). However, it is less likely to undergo volvulus than the ascending colon. In front of it are some coils of small intestine. [WP,unvetted]." [Wikipedia:Descending_colon] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: EFO:0000845 ! descending colon xref: FMA:14547 ! Descending colon xref: galen:DescendingColon xref: MA:0001542 ! descending colon xref: MAT:0000313 ! descending colon xref: MIAA:0000313 ! descending colon xref: ncithesaurus:Descending_Colon xref: OpenCyc:Mx4rwHsNhpwpEbGdrcN5Y29ycA ! descending colon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/ca/Gray1223.png/200px-Gray1223.png xref: BTO:0000641 ! colon descendens is_a: UBERON:0000168 {source="FMA"} ! segment of colon relationship: continuous_with UBERON:0001159 ! sigmoid colon relationship: develops_from UBERON:0001046 {source="Wikipedia"} ! hindgut xref: SCTID:362165006 ! Entire descending colon synonym: "colon descendens" RELATED LATIN [Wikipedia:Descending_colon] xref: http://upload.wikimedia.org/wikipedia/commons/c/ca/Gray1223.png xref: UMLS:C0227389 [Term] id: UBERON:0001159 name: sigmoid colon def: "the part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity." [Wikipedia:Sigmoid_colon] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "sigmoid colon" RELATED [] synonym: "sigmoid flexure" RELATED [] synonym: "colon sigmoideum" RELATED [] synonym: "pelvic colon" RELATED [] xref: BTO:0000645 ! colon sigmoideum xref: EFO:0000846 ! sigmoid colon xref: FMA:14548 ! Sigmoid colon xref: MAT:0000314 ! sigmoid colon xref: MIAA:0000314 ! sigmoid colon xref: ncithesaurus:Sigmoid_Colon xref: ncithesaurus:Sigmoid_Flexure ! sigmoid flexure xref: galen:SigmoidColon ! sigmoid colon xref: OpenCyc:Mx4rwHX_-5wpEbGdrcN5Y29ycA ! sigmoid colon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3b/Dickdarm-Schema.svg/200px-Dickdarm-Schema.svg.png xref: MESH:A03.492.411.495.356.668 ! sigmoid is_a: UBERON:0000168 {source="FMA"} ! segment of colon relationship: continuous_with UBERON:0001052 ! rectum relationship: develops_from UBERON:0001046 {source="Wikipedia"} ! hindgut xref: SCTID:362166007 ! Entire sigmoid colon synonym: "colon sigmoideum" RELATED LATIN [Wikipedia:Sigmoid_colon] xref: http://upload.wikimedia.org/wikipedia/commons/3/3b/Dickdarm-Schema.svg xref: UMLS:C0227391 xref: UMLS:C0682612 [Term] id: UBERON:0009870 name: zone of stomach def: "A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland." [Wikipedia:Stomach#Sections, ISBN10:0073040584] comment: Editor notes: We follow Kardong in defining stomach regions by gland, but we also include 'body of stomach'. In future we may want to have different partitions of the stomach synonym: "gastric zone" EXACT [FMA:14558] synonym: "section of stomach" EXACT [] synonym: "region of stomach" EXACT [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000945 {source="Obol"} ! stomach xref: FMA:14558 ! zone of stomach xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Regions_of_stomach.svg/500px-Regions_of_stomach.svg.png xref: SCTID:245415005 ! Region of stomach (also: UBERON:0009034 'stomach region') [Term] id: UBERON:0001160 name: fundus of stomach def: "The fundus is the portion of the stomach that lies above the cardiac notch, and contains the fundic glands[GO, Kardong]." [GO:0014825, Wikipedia:Fundus_%28stomach%29, ISBN10:0073040584] subset: uberon_slim synonym: "fundus gastricus (ventricularis)" EXACT [] synonym: "gastric fundus" EXACT [] synonym: "stomach fundus" EXACT [] synonym: "fundus gastricus" RELATED [BTO:0000502] synonym: "fundus gastricus ventricularis" RELATED [BTO:0000502] synonym: "fundus ventricularis" RELATED [BTO:0000502] synonym: "fundus ventriculi" RELATED [BTO:0000502] xref: BTO:0000502 ! gastric fundus xref: FMA:14559 ! Fundus of stomach xref: GAID:320 ! gastric fundus xref: galen:GastricFundus xref: VHOG:0000421 ! stomach fundus xref: MA:0001612 ! stomach fundus xref: EFO:0002554 ! gastric fundus xref: EHDAA2:0001919 ! stomach fundus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Gray1046.svg/200px-Gray1046.svg.png xref: EHDAA:4844 ! fundus xref: MESH:A03.492.766.419 ! gastric fundus is_a: UBERON:0009870 ! zone of stomach relationship: has_part UBERON:0010038 ! fundic gastric gland xref: ncithesaurus:Fundus_of_the_Stomach ! Fundus of the Stomach xref: SCTID:362139007 ! Entire gastric fundus xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg property_value: external_definition "The greater curvature of the stomach. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000421", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000421", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0017129 [Term] id: UBERON:0001161 name: body of stomach def: "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]." [GO:0014845, Wikipedia:Body_of_stomach] comment: Note that we include this as zone of stomach even though it is not distinguished by gland type subset: uberon_slim synonym: "corpus gastricum (ventriculare)" EXACT [] synonym: "gastric body" EXACT [] synonym: "gastric corpus" RELATED [] synonym: "stomach body" EXACT [] synonym: "corpus gastricum" RELATED [BTO:0000505] synonym: "corpus ventriculare" RELATED [BTO:0000505] synonym: "corpus ventriculi" RELATED [BTO:0000505] xref: BTO:0000505 xref: FMA:14560 ! Body of stomach xref: galen:GastricCorpus xref: MA:0002559 ! stomach body xref: ncithesaurus:Body_of_Stomach xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Gray1046.svg/200px-Gray1046.svg.png is_a: UBERON:0009870 {source="FMA"} ! zone of stomach synonym: "corpus gastricum" RELATED LATIN [Wikipedia:Body_of_stomach] xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg xref: SCTID:362140009 ! Entire gastric corpus xref: UMLS:C0227230 [Term] id: UBERON:0007650 name: esophagogastric junction def: "the junction between the esophagus and the stomach epithelium" [http://www.thefreedictionary.com/esophagogastric+junction] synonym: "cardioesophageal junction" EXACT [FMA:9434] synonym: "gastroesophageal junction" EXACT [FMA:9434] synonym: "esophageal sphincter" RELATED [MESH:A03.365.414] synonym: "esophagogastric junction" RELATED [MESH:A03.365.414] synonym: "squamocolumnar junction between esophagus and stomach" RELATED [] synonym: "GEJ" RELATED [] xref: FMA:9434 ! esophagogastric junction xref: MESH:A03.365.414 ! esophagogastric junction xref: GAID:292 ! esophagogastric junction xref: BTO:0004364 ! gastroesophageal junction is_a: UBERON:0007651 ! anatomical junction relationship: continuous_with UBERON:0001043 {source="MESH"} ! esophagus relationship: continuous_with UBERON:0001276 {source="tFD"} ! epithelium of stomach xref: ncithesaurus:Gastroesophageal_Junction ! Gastroesophageal Junction xref: SCTID:362130006 ! Entire cardioesophageal junction xref: UMLS:C0014871 [Term] id: UBERON:0001162 name: cardia of stomach alt_id: UBERON:0004712 def: "The part of the stomach attached to the esophagus. The cardia begins immediately distal to the z-line of the gastroeosphageal junction, where the squamous epithelium of the esophagus gives way to the columnar epithelium of the gastrointestinal tract[WP]" [BTO:0000198, Wikipedia:Cardia] comment: Editor notes: We follow Kardong in defining stomach regions by glands. Boundary notes: There were previously conflicting statements in the academic anatomy community[10][11][12] over whether the cardia is part of the stomach, part of the esophagus or a distinct entity. Modern surgical and medical textbooks have agreed that "The gastric cardia is now clearly considered to be part of the stomach"[13][14]. Classical anatomy textbooks, and some other resources[15], describe the cardia as the first of 4 regions of the stomach. This makes sense histologically because the mucosa of the cardia is the same as that of the stomach[WP]. synonym: "antrum cardiacum" RELATED [Wikipedia:Cardia] synonym: "cardiac orifice" RELATED [Wikipedia:Cardia] synonym: "cardiac region" RELATED [Wikipedia:Cardia] synonym: "antrum cardiacum" RELATED LATIN [Wikipedia:Cardia] synonym: "cardial orifice" RELATED [Wikipedia:Cardia] synonym: "cardial part of stomach" EXACT [] synonym: "cardiac antrum" RELATED [] synonym: "gastric cardia" EXACT [] synonym: "pars cardiaca (gaster)" EXACT [] synonym: "stomach cardiac region" EXACT [MA:0001609] synonym: "pars cardiaca gastricae" EXACT LATIN [FMA:TA, FMA:14561] xref: FMA:14561 ! Cardia of stomach xref: MA:0001609 ! stomach cardiac region xref: ncithesaurus:Cardia xref: MESH:A03.492.766.163 ! cardia xref: BTO:0000198 ! cardia xref: GAID:319 ! cardia xref: SCTID:362138004 ! Entire cardia xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Illu_stomach.jpg/200px-Illu_stomach.jpg intersection_of: UBERON:0009870 ! zone of stomach intersection_of: has_part UBERON:0008859 ! cardiac gastric gland relationship: continuous_with UBERON:0001043 ! esophagus relationship: continuous_with UBERON:0001161 ! body of stomach relationship: only_in_taxon NCBITaxon:40674 {source="ISBN10:0073040584"} ! Mammalia xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Illu_stomach.jpg xref: UMLS:C0007144 [Term] id: UBERON:0001163 name: lesser curvature of stomach def: "The lesser curvature of the stomach, extending between the cardiac and pyloric orifices, forms the right or posterior border of the stomach. It descends as a continuation of the right margin of the esophagus in front of the fibers of the right crus of the diaphragm, and then, turning to the right, it crosses the first lumbar vertebra and ends at the pylorus. Nearer its pyloric than its cardiac end is a well-marked notch, the incisura angularis, which varies somewhat in position with the state of distension of the viscus; it serves to separate the stomach into a right and a left portion. The lesser curvature gives attachment to the two layers of the hepatogastric ligament, and between these two layers are the left gastric artery and the right gastric branch of the hepatic artery. [WP,unvetted]." [Wikipedia:Lesser_curvature_of_stomach] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "stomach lesser curvature" EXACT [] xref: FMA:14572 ! Lesser curvature of stomach xref: galen:LesserCurvatureOfStomach xref: MA:0001616 ! stomach lesser curvature xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Gray1046.svg/200px-Gray1046.svg.png is_a: UBERON:0009870 {source="FMA"} ! zone of stomach xref: ncithesaurus:Lesser_Curvature ! Lesser Curvature of the Stomach xref: SCTID:362133008 ! Entire lesser curvature of stomach xref: UMLS:C0227221 [Term] id: UBERON:0001164 name: greater curvature of stomach def: "The greater curvature of the stomach is directed mainly forward, and is four or five times as long as the lesser curvature. [WP,unvetted]." [Wikipedia:Greater_curvature_of_stomach] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "stomach greater curvature" EXACT [] xref: FMA:14574 ! Greater curvature of stomach xref: galen:GreaterCurvatureOfStomach xref: MA:0001615 ! stomach greater curvature xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Gray1046.svg/200px-Gray1046.svg.png is_a: UBERON:0009870 {source="FMA"} ! zone of stomach xref: ncithesaurus:Greater_Curvature ! Greater Curvature of the Stomach xref: SCTID:362134002 ! Entire greater curvature of stomach xref: UMLS:C0227223 [Term] id: UBERON:0001166 ! pylorus name: pylorus def: "The region of the stomach that connects to the duodenum. It is divided in two parts: the pyloric antrum, which connects to the body of the stomach. the pyloric canal, which connects to the duodenum. The pyloric sphincter, or valve, is a strong ring of smooth muscle at the end of the pyloric canal and lets food pass from the stomach to the duodenum. It receives sympathetic innervation from celiac ganglion. [WP,unvetted]." [Wikipedia:Pylorus] comment: Editor notes: We follow Kardong in defining stomach regions by glands subset: uberon_slim synonym: "pars pylorica" EXACT LATIN [] synonym: "pyloric part of stomach" EXACT [] synonym: "stomach pyloric region" EXACT [] synonym: "pyloric region" EXACT [] synonym: "stomach pyloric region" EXACT [EHDAA2:0001580] xref: BTO:0001146 ! pyloric region xref: FMA:14581 ! Pylorus xref: GAID:333 ! pylorus xref: MA:0002560 ! stomach pyloric region xref: EHDAA:4860 ! pyloric region xref: EMAPA:17631 ! pyloric region of stomach of foregut xref: EMAPA:18915 ! pyloric region of stomach of gut xref: ncithesaurus:Pylorus xref: galen:Pylorus ! pylorus xref: VHOG:0000420 ! pyloric region xref: EHDAA2:0001580 ! stomach pyloric region xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Gray1046.svg/200px-Gray1046.svg.png xref: MESH:A03.492.766.799 ! pylorus intersection_of: UBERON:0009870 ! zone of stomach intersection_of: has_part UBERON:0008861 ! pyloric gastric gland intersection_of: has_part UBERON:0001165 ! pyloric antrum intersection_of: has_part UBERON:0008858 ! pyloric canal synonym: "pars pylorica gastricae" EXACT LATIN [FMA:TA, FMA:14581] xref: SCTID:362143006 ! Entire pylorus synonym: "valvula pylori" RELATED LATIN [Wikipedia:Pylorus] xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg property_value: external_definition "The orifice which allows the passage from the stomach into the intestine. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000420", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000420", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "pyloric" xsd:string xref: UMLS:C0034196 [Term] id: UBERON:0001165 name: pyloric antrum def: "Pyloric antrum (antrum, lesser cul-de-sac) is the initial portion of the pyloric part of the stomach. It is near the bottom of the stomach on the left side of the pyloric sphincter, which separates the stomach and the duodenum. It may temporarily become partially or completely shut off from the remainder of the stomach during digestion by peristaltic contraction of the prepyloric sphincter; it is demarcated, sometimes, from the second part of the pyloric part of the stomach by a slight groove. [WP,unvetted]." [Wikipedia:Pyloric_antrum] subset: uberon_slim synonym: "antrum" BROAD [] synonym: "antrum of stomach" EXACT [] synonym: "gastric antrum" RELATED [BTO:0001732] synonym: "antrum of Willis" RELATED [BTO:0001732] synonym: "stomach antrum" RELATED [] synonym: "stomach pyloric antrum" EXACT [] synonym: "antrum pylori" RELATED [BTO:0001732] synonym: "antrum pyloricum" RELATED [BTO:0001732] xref: FMA:14579 ! Pyloric antrum xref: GAID:332 ! pyloric antrum xref: MA:0001624 ! stomach pyloric antrum xref: BTO:0001732 ! gastric antrum xref: EFO:0002555 ! pyloric antrum xref: galen:PyloricAntrum ! pyloric antrum xref: EMAPA:17891 ! pyloric antrum of pyloric region of stomach of foregut xref: EMAPA:18919 ! pyloric antrum of pyloric region of stomach of gut xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Gray1046.svg/200px-Gray1046.svg.png xref: MESH:A03.492.766.716 ! pyloric antrum is_a: UBERON:0009870 {source="FMA"} ! zone of stomach relationship: part_of UBERON:0001166 {source="Wikipedia"} ! pylorus relationship: continuous_with UBERON:0001161 ! body of stomach xref: ncithesaurus:Antrum_Pylori ! Antrum Pylori xref: SCTID:362142001 ! Entire pyloric antrum synonym: "antrum pyloricum" RELATED LATIN [Wikipedia:Pyloric_antrum] xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg xref: UMLS:C0034193 [Term] id: UBERON:0008858 name: pyloric canal def: "the short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter" [MP:0010791, Wikipedia:Pyloric_canal] synonym: "canalis pyloricus" EXACT [Wikipedia:Pyloric_canal] is_a: UBERON:0009870 {source="FMA"} ! zone of stomach relationship: part_of UBERON:0001166 {source="Wikipedia"} ! pylorus relationship: continuous_with UBERON:0001165 ! pyloric antrum relationship: continuous_with UBERON:0001202 ! pyloric sphincter xref: FMA:14580 ! pyloric canal xref: SCTID:245417002 ! Entire pyloric canal synonym: "canalis pyloricus" RELATED LATIN [Wikipedia:Pyloric_canal] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Illu_stomach.jpg [Term] id: UBERON:0011185 name: gastrointestinal sphincter def: "A sphincter muscle that is part of the gastrointestinal system" [OBOL:automatic] intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0005409 ! gastrointestinal system xref: ncithesaurus:Gastrointestinal_Sphincter ! gastrointestinal sphincter xref: UMLS:C1517464 [Term] id: UBERON:0001202 name: pyloric sphincter def: "A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]." [UBERON:cjm] subset: uberon_slim synonym: "pyloric valve" EXACT [Wikipedia:Pylorus] xref: FMA:14916 ! Pyloric sphincter xref: VHOG:0001466 ! pyloric sphincter xref: XAO:0000457 ! pyloric sphincter xref: ncithesaurus:Pyloric_Sphincter ! Pyloric Sphincter xref: OpenCyc:Mx4rvly2ZZwpEbGdrcN5Y29ycA ! pyloric sphincter xref: MA:0002952 ! pyloric sphincter xref: EMAPA:19251 ! pyloric sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0001166 ! pylorus relationship: continuous_with UBERON:0008858 ! pyloric canal relationship: adjacent_to UBERON:0002114 ! duodenum xref: AAO:0011093 ! pyloric sphincter xref: SCTID:268073008 ! Entire pyloric sphincter property_value: homology_notes "(...) the adult Xenopus stomach exhibits both glandular and aglandular regions and a distinct pyloric sphincter similar to that of the amniotic vertebrates (...).[uncertain][VHOG]" xsd:string {external_class="VHOG:0001466", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00076.x", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0227238 [Term] id: UBERON:0010238 name: torus pylorus def: "A fleshy protuberance at the pylorus of some species such as ruminants and pigs, that projects into the lumen of the pyloric canal" [http://medical-dictionary.thefreedictionary.com/torus+pyloricus] synonym: "torus pyloricus" EXACT [] is_a: UBERON:0009034 {source="MA"} ! stomach region relationship: part_of UBERON:0001166 ! pylorus relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: never_in_taxon NCBITaxon:314146 ! Euarchontoglires xref: SCTID:14214007 ! Torus pyloricus [Term] id: UBERON:0013472 ! upper esophagus name: upper esophagus synonym: "upper third of esophagus" RELATED [] xref: SCTID:276801001 ! Entire upper third of esophagus xref: ncithesaurus:Upper_Third_of_the_Esophagus ! upper third of the esophagus is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0013473 name: lower esophagus synonym: "lower third of esophagus" RELATED [] xref: SCTID:362129001 ! Entire lower third of esophagus xref: ncithesaurus:Lower_Third_of_the_Esophagus ! lower third of the esophagus is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0013474 name: middle part of esophagus synonym: "middle third of esophagus" RELATED [] xref: SCTID:276802008 ! Entire middle third of esophagus xref: ncithesaurus:Middle_Third_of_the_Esophagus ! middle third of the esophagus is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0007652 name: esophageal sphincter def: "A sphincter muscle that is part of an esophagus." [OBOL:accepted] comment: editor note - check for specific subtypes across species. Note mammals have upper and lower, but lower is really part of cardia and thus is not classified under here synonym: "oesophagial sphincter" EXACT [ZFA:0000415] xref: ZFA:0000415 ! esophageal sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0001043 ! esophagus xref: SCTID:277765007 ! Esophageal sphincter xref: TAO:0000415 ! esophageal sphincter [Term] id: UBERON:0007268 ! upper esophageal sphincter name: upper esophageal sphincter def: "The upper esophageal sphincter (UES) (also called the Pharyngoesophageal sphincter) refers to the superior portion of the esophagus. Unlike the lower esophageal sphincter, it consists of striated muscle and is under conscious control. The primary muscle of the UES is the cricopharyngeus portion of the inferior pharyngeal constrictor. During swallowing the upper esophageal sphincter opens so the bolus can pass into the esophagus. A secondary role of the UES is to reduce backflow from the esophagus into the pharynx." [Wikipedia:Upper_esophageal_sphincter] synonym: "upper esophageal sphincter muscle" EXACT [] synonym: "upper oesophageal sphincter" EXACT [Wikipedia:Upper_esophageal_sphincter] synonym: "pharyngoesophageal sphincter" EXACT [Wikipedia:Upper_esophageal_sphincter] is_a: UBERON:0004590 ! sphincter muscle relationship: overlaps UBERON:0013472 ! upper esophagus relationship: composed_primarily_of UBERON:0002036 {source="Wikipedia"} ! striated muscle tissue xref: ncithesaurus:Upper_Esophageal_Sphincter ! Upper Esophageal Sphincter xref: http://upload.wikimedia.org/wikipedia/commons/2/22/Musculusconstrictorpharyngisinferior.png xref: UMLS:C1451819 [Term] id: UBERON:0004550 name: gastroesophageal sphincter def: "A sphincter muscle that is part of a cardia of stomach [Automatically generated definition]." [OBOL:automatic] comment: todo - split? check FMA:63048 ! circular muscle layer of abdominal part of esophagus synonym: "cardiac sphincter" RELATED [MA:0002951] synonym: "lower esophageal sphincter" RELATED [MA:0002951] synonym: "gastroesophageal sphincter" EXACT [FMA:14915] synonym: "inferior esophageal sphincter" EXACT [FMA:14915] synonym: "cardiac sphincter" RELATED [Wikipedia:Cardia] synonym: "esophageal sphincter" RELATED [Wikipedia:Cardia] synonym: "esophageal sphincter%2c lower" RELATED [Wikipedia:Cardia] synonym: "esophageal-cardiac junction" RELATED [Wikipedia:Cardia] synonym: "esophagogastric junction" RELATED [Wikipedia:Cardia] synonym: "gastro-esophageal junction" RELATED [Wikipedia:Cardia] synonym: "gastro-esophageal sphincter" RELATED [Wikipedia:Cardia] synonym: "gastro-oesophageal junction" RELATED [Wikipedia:Cardia] synonym: "gastroesophageal junction" RELATED [Wikipedia:Cardia] synonym: "gastroesophageal sphincter" RELATED [Wikipedia:Cardia] synonym: "lower esophageal sphincter" RELATED [Wikipedia:Cardia] synonym: "gastroesophageal sphincter muscle" EXACT [] synonym: "LES" RELATED [Wikipedia:Cardia] xref: FMA:14915 ! Cardiac sphincter xref: MA:0002951 ! gastroesophageal sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0001162 {source="MA"} ! cardia of stomach xref: ncithesaurus:Lower_Esophageal_Sphincter ! Lower Esophageal Sphincter xref: galen:LowerEsophagealSphincter xref: galen:LowerEsophagealSphincter xref: SCTID:267809009 ! Entire inferior esophageal sphincter xref: UMLS:C0227192 [Term] id: UBERON:0001167 name: wall of stomach def: "An anatomical wall that is part of a stomach [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "gastric wall" EXACT [] synonym: "stomach wall" EXACT [] synonym: "anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "stomach anatomical wall" EXACT [OBOL:automatic] synonym: "ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "ventriculus wall" EXACT [OBOL:automatic] synonym: "wall of ventriculus" EXACT [OBOL:automatic] xref: FMA:14582 ! Wall of stomach xref: MA:0002692 ! stomach wall xref: galen:WallOfStomach ! wall of stomach is_a: UBERON:0000060 ! wall intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0000945 ! stomach xref: SCTID:279995000 ! Entire wall of stomach [Term] id: UBERON:0001168 name: wall of small intestine def: "An anatomical wall that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "small intestinal wall" EXACT [] synonym: "small intestine wall" EXACT [] synonym: "anatomical wall of small bowel" EXACT [OBOL:automatic] synonym: "anatomical wall of small intestine" EXACT [OBOL:automatic] synonym: "small bowel anatomical wall" EXACT [OBOL:automatic] synonym: "small bowel wall" EXACT [OBOL:automatic] synonym: "small intestine anatomical wall" EXACT [OBOL:automatic] synonym: "wall of small bowel" EXACT [OBOL:automatic] xref: FMA:14615 ! Wall of small intestine xref: MA:0002696 ! small intestine wall xref: ncithesaurus:Small_Intestinal_Wall_Tissue ! small intestinal wall tissue is_a: UBERON:0000060 ! wall intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0002108 ! small intestine xref: UMLS:C1519375 [Term] id: UBERON:0001169 name: wall of large intestine def: "An anatomical wall that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "large intestinal wall" EXACT [] synonym: "large intestine wall" EXACT [] synonym: "anatomical wall of large intestine" EXACT [OBOL:automatic] synonym: "large intestine anatomical wall" EXACT [OBOL:automatic] xref: FMA:14619 ! Wall of large intestine xref: MA:0002695 ! large intestine wall is_a: UBERON:0000060 ! wall intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001262 ! wall of intestine [Term] id: UBERON:0009911 name: lobule subset: upper_level is_a: UBERON:0000064 ! organ part xref: FMA:45737 ! lobule xref: ncithesaurus:Lobule ! Lobule xref: UMLS:C0921005 [Term] id: UBERON:0009912 name: anatomical lobe subset: upper_level is_a: UBERON:0000064 ! organ part xref: FMA:45728 ! anatomical lobe [Term] id: UBERON:0009913 name: renal lobe def: "the portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]." [MP:0011381, Wikipedia:Renal_lobe] comment: Edtor note: todo - add has_part relationships. Taxon notes: human kidneys have multilobar (multipyramidal) architecture while mice and rats have unilobar (unipyramidal) kidneys[MP] synonym: "kidney lobe" EXACT [MP:0011381] synonym: "lobus renalis" EXACT [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "lobi renalis" EXACT PLURAL [Wikipedia:Renal_lobe] intersection_of: UBERON:0009912 ! anatomical lobe intersection_of: part_of UBERON:0002113 ! kidney xref: FMA:17881 ! renal lobe xref: ncithesaurus:Kidney_Lower_Lobe ! kidney lobe synonym: "lobi renales" RELATED LATIN [Wikipedia:Renal_lobe] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png xref: UMLS:C0736382 [Term] id: UBERON:0009914 name: renal lobule def: "the portion of a renal lobe consisting of nephrons grouped around a single medullary ray and draining into a single collecting duct; human kidneys have multilobular, multipapillary architecture while mice and rats have unilobular, unipapillary kidneys" [MP:0011382, Wikipedia:Cortical_lobule] comment: Alternate definition: One of the subdivisions of the kidney, consisting of a medullary ray and that portion of the convoluted port (renal corpuscles and convoluted tubules) associated with its collecting duct. -http://www.mondofacto.com/facts/dictionary?lobulus+corticalis+renalis synonym: "kidney lobule" EXACT [MP:0011382] synonym: "lobulus renalis" EXACT [] synonym: "cortical lobule" RELATED [MP:0011382, Wikipedia:Cortical_lobule] synonym: "cortical lobule of kidney" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "lobulus corticalis renalis" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "renal cortical lobule" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "renculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "reniculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "renunculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] intersection_of: UBERON:0009911 ! lobule intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0009913 {source="FMA"} ! renal lobe xref: FMA:17670 ! renal lobule synonym: "lobuli corticales renis" RELATED LATIN [Wikipedia:Cortical_lobule] xref: SCTID:361330004 ! Entire cortical lobule of kidney [Term] id: UBERON:0001171 name: portal lobule def: "the triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel." [MP:0008992] comment: This class was created automatically from a combination of ontologies xref: FMA:14653 ! Portal lobule xref: MA:0002498 ! portal lobule xref: ncithesaurus:Portal_Lobule ! Portal Lobule is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001280 ! liver parenchyma xref: UMLS:C0682620 [Term] id: UBERON:0010704 name: parenchyma of quadrate lobe of liver intersection_of: UBERON:0001280 ! liver parenchyma intersection_of: part_of UBERON:0001116 ! quadrate lobe of liver xref: FMA:71676 ! parenchyma of quadrate lobe of liver xref: EMAPA:18320 ! parenchyma of quadrate lobe xref: EHDAA2:0001014 ! liver right quadrate lobe parenchyma synonym: "liver right quadrate lobe parenchyma" EXACT [EHDAA2:0001014] synonym: "parenchyma of quadrate lobe" EXACT [EMAPA:18320] def: "A liver parenchyma that is part of a quadrate lobe of liver." [OBOL:automatic] [Term] id: UBERON:0010706 name: parenchyma of caudate lobe of liver intersection_of: UBERON:0001280 ! liver parenchyma intersection_of: part_of UBERON:0001117 ! caudate lobe of liver xref: FMA:71659 ! parenchyma of caudate lobe of liver xref: EMAPA:18315 ! parenchyma of caudate lobe xref: EHDAA2:0001007 ! liver right caudate lobe parenchyma synonym: "parenchyma of caudate lobe" EXACT [EMAPA:18315] synonym: "liver right caudate lobe parenchyma" EXACT [EHDAA2:0001007] def: "A liver parenchyma that is part of a caudate lobe of liver." [OBOL:automatic] [Term] id: UBERON:0001172 name: hepatic acinus comment: This class was created automatically from a combination of ontologies synonym: "liver acinus" EXACT [] synonym: "portal acinus" EXACT [] xref: FMA:14654 ! Hepatic acinus xref: MA:0002496 ! liver acinus xref: ncithesaurus:Liver_Acinus ! Liver Acinus is_a: UBERON:0009842 {source="FMA"} ! acinus relationship: part_of UBERON:0001171 ! portal lobule relationship: part_of UBERON:0004647 ! liver lobule xref: SCTID:272214009 ! Entire hepatic acinus xref: UMLS:C0227519 [Term] id: UBERON:0010081 name: future common hepatic duct is_a: UBERON:0003914 ! epithelial tube relationship: develops_from UBERON:0005604 ! hepatic duct extrahepatic part intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: develops_into UBERON:0001175 ! common hepatic duct xref: EHDAA2:0000595 ! future common hepatic duct def: "An extrahepatic bile duct that develops_into a common hepatic duct." [OBOL:automatic] [Term] id: UBERON:0002394 name: bile duct def: "Duct that carries bile from the liver to the small intestine." [Wikipedia:Bile_duct, ZFA:0001100] comment: The path is as follows: Bile canaliculi → Canals of Hering → interlobular bile ducts → intrahepatic bile ducts → left and right hepatic ducts merge to form → common hepatic duct exits liver and joins → cystic duct (from gall bladder) forming → common bile duct → joins with pancreatic duct → forming ampulla of Vater → enters duodenum [WP] subset: uberon_slim synonym: "hepatic duct" RELATED [] synonym: "gall duct" RELATED [BTO:0000122] xref: BTO:0000122 xref: FMA:9706 ! Bile duct xref: GAID:280 ! bile duct xref: VHOG:0000212 ! bile duct xref: MA:0000354 ! bile duct xref: ncithesaurus:Bile_Duct xref: OpenCyc:Mx4rvdCds5wpEbGdrcN5Y29ycA xref: XAO:0000134 ! bile duct xref: OpenCyc:Mx4rvdCds5wpEbGdrcN5Y29ycA ! bile duct xref: EHDAA2:0000741 ! hepatic duct (also: UBERON:0005171 'hepatic duct') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5d/Digestive_system_showing_bile_duct.png/200px-Digestive_system_showing_bile_duct.png xref: MESH:A03.159.183 ! bile duct xref: EV:0100091 ! bile duct is_a: UBERON:0000058 ! duct intersection_of: UBERON:0000058 ! duct intersection_of: channel_for UBERON:0001970 ! bile relationship: part_of UBERON:0002294 ! biliary system relationship: develops_from UBERON:0008835 {source="XAO"} ! hepatic diverticulum relationship: part_of UBERON:0001173 {source="MA"} ! biliary tree relationship: has_part CL:0000168 {gci_relation="part_of", gci_filler="NCBITaxon:7769", source="PMID:16417468"} ! insulin secreting cell xref: AAO:0011019 ! bile duct xref: SCTID:276157007 ! Entire bile duct xref: http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png synonym: "biliary duct" RELATED [FMA:9706] property_value: external_definition "Any of the excretory ducts in the liver that convey bile between the liver and the intestine. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000212", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/bile+duct", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the amphibian liver has characteristics in common with both fish and terrestrial vertebrates. (...) The histological structure of the liver is similar to that in other vertebrates, with hepatocytes arranged in clusters and cords separated by a meshwork of sinusoids and the presence of the traditional triad of portal venule, hepatic arteriole, and bile duct.[well established][VHOG]" xsd:string {external_class="VHOG:0000212", ontology="VHOG", source="DOI:10.1053/ax.2000.7133 Crawshaw GJ\, Weinkle TK\, Clinical and pathological aspects of the amphibian liver. Seminars in Avian and Exotic Pet Medicine (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0005400 [Term] id: UBERON:0005171 name: hepatic duct def: "The hepatic duct is the duct that leads from the liver to the bile duct[GO]. A duct that carries bile from the liver to the small intestine[ZFA]." [GO:0061011] comment: TODO - MA distinguishes between bile duct, hepatic duct, common bile duct and common hepatic duct. in FMA hepatic duct and common hepatic duct are the same subset: vertebrate_core xref: MA:0000357 ! hepatic duct xref: EHDAA2:0000741 ! hepatic duct (also: UBERON:0002394 'bile duct') xref: EHDAA:3049 ! hepatic duct xref: VHOG:0000219 ! hepatic duct xref: galen:HepaticDuct xref: TAO:0001100 ! hepatic duct xref: ZFA:0001100 ! hepatic duct xref: OpenCyc:Mx4rvWo8WJwpEbGdrcN5Y29ycA ! hepatic duct xref: EMAPA:16843 ! hepatic duct of liver and biliary system xref: EMAPA:18672 ! hepatic duct of left of lobe of liver is_a: UBERON:0002394 ! bile duct relationship: continuous_with UBERON:0002107 ! liver relationship: part_of UBERON:0001173 ! biliary tree xref: ncithesaurus:Hepatic_Duct ! Hepatic Duct xref: SCTID:245399002 ! Entire hepatic duct property_value: external_definition "A duct that carries bile from the liver to the small intestine.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001100", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "The excretory duct of the liver or one of its branches in the lobes of the liver. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000219", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/hepatic+duct", source="http://bgee.unil.ch/"} xref: UMLS:C0917710 [Term] id: UBERON:0001175 name: common hepatic duct def: "Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]." [Wikipedia:Common_hepatic_duct, ZFIN:curator] comment: TODO - MA distinguishes between bile duct, hepatic duct, common bile duct and common hepatic duct. in FMA hepatic duct and common hepatic duct are the same. Common is part of extra-hepatic part subset: uberon_slim synonym: "hepatic duct" RELATED [] xref: FMA:14668 ! Common hepatic duct xref: GAID:286 ! common hepatic duct xref: VHOG:0000220 ! common hepatic duct xref: MA:0002660 ! common hepatic duct xref: ncithesaurus:Common_Hepatic_Duct ! Common Hepatic Duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/48/Illu_liver_gallbladder.jpg/200px-Illu_liver_gallbladder.jpg xref: EMAPA:19101 ! common of extrahepatic part of hepatic duct of liver and biliary system xref: MESH:A03.159.183.079.600 ! common hepatic duct relationship: immediate_transformation_of UBERON:0010081 {evidence="definitional"} ! future common hepatic duct is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct relationship: part_of UBERON:0005604 {source="MA"} ! hepatic duct extrahepatic part relationship: continuous_with UBERON:0001176 {source="Wikipedia"} ! right hepatic duct relationship: continuous_with UBERON:0001177 {source="Wikipedia"} ! left hepatic duct relationship: channel_for UBERON:0001970 ! bile relationship: channels_into UBERON:0001174 ! common bile duct xref: SCTID:245403006 ! Entire common hepatic duct synonym: "ductus hepaticus communis" RELATED LATIN [Wikipedia:Common_hepatic_duct] xref: http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg property_value: external_definition "The duct which conveys the bile from the liver and unites with the cystic duct to form the common bile duct. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000220", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0019149 [Term] id: UBERON:0003703 name: extrahepatic bile duct def: "Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct." [MESH:A03.159.183.079] subset: vertebrate_core synonym: "extrahepatic biliary system" RELATED [GAID:281] synonym: "bile duct extrahepatic part" RELATED [MA:0002659] synonym: "extrahepatic biliary system" RELATED [] xref: MA:0002659 ! bile duct extrahepatic part xref: FMA:14678 ! Extrahepatic bile duct xref: GAID:281 ! extrahepatic bile duct xref: ncithesaurus:Extrahepatic_Bile_Duct ! Extrahepatic Bile Duct xref: MESH:A03.159.183.079 ! extrahepatic bile duct is_a: UBERON:0002394 ! bile duct relationship: spatially_disjoint_from UBERON:0002107 ! liver xref: SCTID:276158002 ! Entire extrahepatic bile duct xref: UMLS:C0206187 [Term] id: UBERON:0003704 name: intrahepatic bile duct def: "Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct." [MESH:A03.159.183.158] subset: vertebrate_core synonym: "bile duct intrahepatic part" EXACT [MA:0001630] synonym: "intrahepatic biliary system" RELATED [] xref: MA:0001630 ! bile duct intrahepatic part xref: FMA:15766 ! Intrahepatic bile duct xref: GAID:287 ! intrahepatic bile duct xref: ZFA:0005169 ! intrahepatic bile duct xref: ncithesaurus:Intrahepatic_Bile_Duct ! Intrahepatic Bile Duct xref: MESH:A03.159.183.158 ! intrahepatic bile duct is_a: UBERON:0002394 {source="FMA"} ! bile duct relationship: part_of UBERON:0002107 {source="MA"} ! liver intersection_of: UBERON:0002394 ! bile duct intersection_of: part_of UBERON:0002107 ! liver xref: SCTID:362193005 ! Entire intrahepatic bile duct xref: TAO:0005169 ! intrahepatic bile duct property_value: external_definition "Duct that collects bile from the bile ductules and connects to the extrahepatic bile duct.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005169", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0005401 [Term] id: UBERON:0004058 name: biliary ductule def: "One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP]" [MP:0009494, BTO:0002840] comment: ZFIN: Digestive system duct that collects bile from the canaliculus and transports bile through the liver -- (check if the same) // The smallest and the most peripheral branches of the biliary tree consist of a portal part (portal ductule) and an intralobular part (intralobular ductule) // xref: BTO:0002840 ! bile ductule xref: ZFA:0005164 ! bile ductule synonym: "bile capillary" RELATED [BTO:0002840] synonym: "biliary ductule" RELATED [BTO:0002840] synonym: "cholangiole" RELATED [BTO:0002840] synonym: "bile ductule" EXACT [BTO:0002840] synonym: "biliary ductule" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi] synonym: "ductuli biliferi" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi] is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0002394 {source="BTO"} ! bile duct relationship: adjacent_to UBERON:0001175 ! common hepatic duct relationship: part_of UBERON:0002107 ! liver xref: TAO:0005164 ! bile ductule [Term] id: UBERON:0001282 name: intralobular bile duct def: "The Canals of Hering, or intrahepatic bile ductules, are part of the outflow system of exocrine bile product from the liver." [Wikipedia:Canals_of_Hering] comment: Editor notes: Note that this is part of the intrahepatic bile duct in MA, as this class is more alike the tree in FMA. Note also that SCT has canal of Hering and Entire IBduct as the only sibling terms under 'Structure of intralobular bile duct' (i.e. the CoH is the only part of the entire IBduct) subset: uberon_slim synonym: "canal of Herring" EXACT [FMA:17545] synonym: "cholangiole" EXACT [FMA:17545] synonym: "canal of Hering" RELATED [] synonym: "cholangiole" EXACT [] synonym: "canals of Hering" RELATED PLURAL [Wikipedia:Canals_of_Hering] synonym: "duct of Herring" RELATED [Wikipedia:Canals_of_Hering] synonym: "intrahepatic bile ductule" RELATED [Wikipedia:Canals_of_Hering] xref: FMA:17545 ! Intralobular bile duct xref: MA:0002669 ! intralobular bile duct is_a: UBERON:0003704 {source="FMA"} ! intrahepatic bile duct relationship: part_of UBERON:0004647 {source="FMA"} ! liver lobule relationship: part_of UBERON:0001172 {source="FMA"} ! hepatic acinus xref: ncithesaurus:Canal_of_Hering ! Canal of Hering xref: SCTID:269922006 ! Entire intralobular bile duct xref: SCTID:227002 ! Canal of Hering xref: UMLS:C0227517 [Term] id: UBERON:0001246 name: interlobular bile duct def: "the canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad." [MP:0009500] comment: This class was created automatically from a combination of ontologies xref: FMA:15767 ! Interlobular bile duct xref: MA:0002668 ! interlobular bile duct xref: ncithesaurus:Interlobular_Bile_Duct ! Interlobular Bile Duct is_a: UBERON:0003704 {source="FMA"} ! intrahepatic bile duct relationship: part_of UBERON:0001279 {source="FMA"} ! portal triad xref: SCTID:83488001 ! Structure of interlobular bile duct xref: UMLS:C0227515 [Term] id: UBERON:0001174 ! common bile duct name: common bile duct def: "a tube-like anatomic structure in the human gastrointestinal tract. It is formed by the union of the common hepatic duct and the cystic duct (from the gall bladder). It is later joined by the pancreatic duct to form the ampulla of Vater. There, the two ducts are surrounded by the muscular sphincter of Oddi." [Wikipedia:Common_bile_duct] subset: uberon_slim subset: vertebrate_core synonym: "ductus choledochus (biliaris)" EXACT [] synonym: "ductus choledochus" RELATED LATIN [Wikipedia:Common_bile_duct] xref: EHDAA:3981 ! common bile duct xref: FMA:14667 ! Common bile duct xref: GAID:282 ! common bile duct xref: galen:CommonBileDuct xref: VHOG:0000214 ! common bile duct xref: MA:0001631 ! common bile duct xref: ZFA:0005165 ! common bile duct xref: ncithesaurus:Common_Bile_Duct ! Common Bile Duct xref: EHDAA2:0000303 ! common bile duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5d/Digestive_system_showing_bile_duct.png/200px-Digestive_system_showing_bile_duct.png xref: EMAPA:17201 ! common bile duct xref: MESH:A03.159.183.079.300 ! common bile duct is_a: UBERON:0003703 ! extrahepatic bile duct relationship: part_of UBERON:0001173 ! biliary tree relationship: channel_for UBERON:0001970 ! bile relationship: channels_into UBERON:0001064 ! main pancreatic duct relationship: continuous_with UBERON:0001152 ! cystic duct relationship: continuous_with UBERON:0001175 ! common hepatic duct xref: SCTID:362199009 ! Entire common bile duct xref: TAO:0005165 ! common bile duct xref: http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png property_value: external_definition "Digestive system duct that collects bile from the hepatic bile duct and the cystic duct.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005165", date_retrieved="2012-08-14", source="ZFIN:Curator"} property_value: external_definition "The duct formed by the union of the common hepatic and cystic ducts. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000214", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0009437 [Term] id: UBERON:0001176 name: right hepatic duct def: "The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26034] comment: This class was created automatically from a combination of ontologies synonym: "ductus hepaticus dexter" RELATED LATIN [] xref: EHDAA:3992 ! right hepatic duct xref: FMA:14669 ! Right hepatic duct xref: VHOG:0000217 ! right hepatic duct xref: MA:0001639 ! right hepatic duct xref: ncithesaurus:Right_Hepatic_Duct ! Right Hepatic Duct xref: EHDAA2:0001727 ! right hepatic duct xref: EMAPA:19100 ! right of extrahepatic part of hepatic duct of liver and biliary system xref: EMAPA:18305 ! right of intrahepatic part of hepatic duct of liver and biliary system intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: continuous_with UBERON:0001114 ! right lobe of liver relationship: part_of UBERON:0005171 ! hepatic duct xref: SCTID:245401008 ! Entire right hepatic duct property_value: external_definition "The duct which drains bile from the right half of the liver and unites with the left hepatic duct to form the common hepatic duct. [adapted_from_http://www.medterms.com/script/main/art.asp?articlekey=26032][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000217", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0227557 [Term] id: UBERON:0001177 name: left hepatic duct def: "The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26035] synonym: "ductus hepaticus sinister" RELATED LATIN [] xref: EHDAA:3990 ! left hepatic duct xref: FMA:14670 ! Left hepatic duct xref: VHOG:0000218 ! left hepatic duct xref: MA:0001638 ! left hepatic duct xref: ncithesaurus:Left_Hepatic_Duct ! Left Hepatic Duct xref: EHDAA2:0000941 ! left hepatic duct xref: EMAPA:19099 ! left of extrahepatic part of hepatic duct of liver and biliary system xref: EMAPA:18304 ! left of intrahepatic part of hepatic duct of liver and biliary system intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: continuous_with UBERON:0001115 ! left lobe of liver relationship: part_of UBERON:0005171 ! hepatic duct xref: SCTID:245400009 ! Entire left hepatic duct property_value: external_definition "The duct which drains bile from the left half of the liver and unites with the right hepatic duct to form the common hepatic duct. [adapted_from_http://www.medterms.com/script/main/art.asp?articlekey=26032][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000218", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0227560 [Term] id: UBERON:0001283 name: bile canaliculus def: "Fine tubular canals running between liver cells, throughout the parenchyma, usually occurring singly between each adjacent pair of cells, and forming a three-dimensional network of polyhedral meshes, with a single cell in each mesh[BTO]. A thin tube that collects bile secreted by hepatocytes. The bile canaliculi merge and form bile ductules, which eventually become common hepatic duct. Hepatocytes are polyhedral in shape, therefore having no set shape or design. They have surfaces facing the sinusoids, (called sinusoidal faces) and surfaces which contact other hepatocytes, (called lateral faces). Bile canaliculi are formed by grooves on some of the lateral faces of these hepatocytes. Microvilli are present in the canaliculi but are sparse. [WP,unvetted]." [Wikipedia:Bile_canaliculus, BTO:0002841] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "bile capillary" RELATED [BTO:0002841] synonym: "biliary canaliculus" RELATED [BTO:0002841] synonym: "bile canaliculi" RELATED PLURAL [Wikipedia:Bile_canaliculus] xref: FMA:17547 ! Bile canaliculus xref: MA:0002495 ! bile canaliculus xref: ZFA:0005163 ! bile canaliculus xref: ncithesaurus:Bile_Canaliculus ! Bile Canaliculus xref: BTO:0002841 ! bile canaliculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d9/Gray1094.png/200px-Gray1094.png xref: MESH:A03.159.183.158.125 ! bile canaliculi is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0004647 {source="FMA"} ! liver lobule relationship: part_of UBERON:0005452 {source="FMA"} ! hepatic plate relationship: part_of UBERON:0001172 {source="FMA"} ! hepatic acinus relationship: part_of UBERON:0002394 {source="BTO"} ! bile duct xref: SCTID:270023005 ! Entire bile canaliculus xref: TAO:0005163 ! bile canaliculus xref: http://upload.wikimedia.org/wikipedia/commons/d/d9/Gray1094.png xref: UMLS:C0005393 [Term] id: UBERON:0001182 name: superior mesenteric artery def: "In human anatomy, the superior mesenteric artery (SMA) arises from the anterior surface of the abdominal aorta, just inferior to the origin of the celiac trunk, and supplies the intestine from the lower part of the duodenum through two-thirds of the transverse colon, as well as the pancreas. [WP,unvetted]." [Wikipedia:Superior_mesenteric_artery] subset: uberon_slim synonym: "superior mesenteric arterial tree" EXACT [] synonym: "arteria mesenterica superior" RELATED [BTO:0002303] xref: EHDAA:3358 ! superior mesenteric artery xref: EHDAA:5313 ! superior mesenteric artery xref: FMA:14749 ! Superior mesenteric artery xref: GAID:502 ! superior mesenteric artery xref: VHOG:0000754 ! superior mesenteric artery xref: MA:0002005 ! superior mesenteric artery xref: ncithesaurus:Superior_Mesenteric_Artery ! Superior Mesenteric Artery xref: BTO:0002303 ! superior mesenteric artery xref: galen:SuperiorMesentericArtery ! superior mesenteric artery xref: OpenCyc:Mx4rwE5KipwpEbGdrcN5Y29ycA ! superior mesenteric artery xref: EHDAA2:0001949 ! superior mesenteric artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/68/Gray1099.png/200px-Gray1099.png xref: EMAPA:18619 ! superior of mesenteric artery xref: MESH:A07.231.114.565.755 ! superior mesenteric artery is_a: UBERON:0005616 {source="MA"} ! mesenteric artery relationship: supplies UBERON:0000160 ! intestine xref: SCTID:362048004 ! Entire superior mesenteric artery synonym: "arteria mesenterica superior" RELATED LATIN [Wikipedia:Superior_mesenteric_artery] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Superior_mesenteric_a.gif xref: UMLS:C0162861 [Term] id: UBERON:0001183 name: inferior mesenteric artery def: "In human anatomy, the inferior mesenteric artery, often abbreviated as IMA, supplies the large intestine from the left colic (or splenic) flexure to the upper part of the rectum, which includes the descending colon, the sigmoid colon, and part of the rectum. Proximally, its territory of distribution overlaps (forms a watershed) with the middle colic artery, and therefore the superior mesenteric artery. The SMA and IMA anastomose via the marginal artery (artery of Drummond). The territory of distribution of the IMA is more or less equivalent to the embryonic hindgut. [WP,unvetted]." [Wikipedia:Inferior_mesenteric_artery] subset: uberon_slim synonym: "IMA" BROAD ABBREVIATION [] synonym: "inferior mesenteric arterial tree" EXACT [] synonym: "arteria mesenterica inferior" RELATED [BTO:0002302] synonym: "arteria mesenterica inferior" RELATED LATIN [Wikipedia:Inferior_mesenteric_artery] xref: EHDAA:4345 ! inferior mesenteric artery xref: FMA:14750 ! Inferior mesenteric artery xref: GAID:501 ! inferior mesenteric artery xref: galen:InferiorMesentericArtery xref: VHOG:0001116 ! inferior mesenteric artery xref: MA:0002004 ! inferior mesenteric artery xref: OpenCyc:Mx4rv-t-S5wpEbGdrcN5Y29ycA xref: ncithesaurus:Inferior_Mesenteric_Artery ! Inferior Mesenteric Artery xref: BTO:0002302 ! inferior mesenteric artery xref: OpenCyc:Mx4rv-t-S5wpEbGdrcN5Y29ycA ! inferior mesenteric artery xref: EHDAA2:0000817 ! inferior mesenteric artery xref: EMAPA:18618 ! inferior of mesenteric artery xref: MESH:A07.231.114.565.510 ! inferior mesenteric artery is_a: UBERON:0005616 {source="MA"} ! mesenteric artery relationship: supplies UBERON:0000059 ! large intestine xref: SCTID:181341006 ! Entire inferior mesenteric artery xref: http://upload.wikimedia.org/wikipedia/commons/e/e4/Gray538.png xref: UMLS:C0162860 [Term] id: UBERON:0001184 name: renal artery def: "One of two laterally paired arteries that supplies the kidneys. These are large arteries that branch from the dorsal aorta in primitive vertebrates." [ISBN10:0073040584, Wikipedia:Renal_artery] comment: Editor notes: renal arteries vary widely even in humans. Sub-structures should be checked for taxon variability. subset: uberon_slim subset: vertebrate_core synonym: "renal arterial tree" EXACT [] synonym: "renal arteries" RELATED PLURAL [] xref: BTO:0001165 xref: EHDAA:5321 ! renal artery xref: EHDAA:8594 ! renal artery xref: FMA:14751 ! Renal artery xref: GAID:507 ! renal artery xref: MA:0002035 ! renal artery xref: OpenCyc:Mx4rveOFHpwpEbGdrcN5Y29ycA xref: TAO:0000420 ! renal artery xref: ZFA:0000420 ! renal artery xref: ncithesaurus:Renal_Artery ! Renal Artery xref: EFO:0002552 ! renal artery xref: galen:RenalArtery ! renal artery xref: OpenCyc:Mx4rveOFHpwpEbGdrcN5Y29ycA ! renal artery xref: RETIRED_EHDAA2:0001600 ! renal artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Gray1120.png/200px-Gray1120.png xref: EMAPA:17862 ! renal artery of arterial system of cardiovascular system of organ system xref: EMAPA:28373 ! renal artery of renal arterial system xref: MESH:A07.231.114.745 ! renal artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002113 ! kidney relationship: branch_of UBERON:0001516 {source="Wikipedia", notes="dorsal aorta in Kardong"} ! abdominal aorta xref: AAO:0010223 ! renal artery xref: EHDAA2:0004100 ! renal artery xref: SCTID:181339005 ! Entire renal artery synonym: "arteria renalis" RELATED LATIN [Wikipedia:Renal_artery] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png property_value: external_definition "Artery which supplies blood via branches to the gonads, oviducts, and kidneys.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010223", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The renal arteries normally arise off the side of the abdominal aorta, immediately below the superior mesenteric artery, and supply the kidneys with blood. Each is directed across the crus of the diaphragm, so as to form nearly a right angle with the aorta. The renal arteries carry a large portion of total blood flow to the kidneys. Up to a third of total cardiac output can pass through the renal arteries to be filtered by the kidneys. The arterial supply of the kidneys is variable and there may be one or more renal arteries supplying each kidney. It is located above the renal vein. It has a radius of approximately 0.25cm, 0.26 cm at the root. The measured mean diameter can differ depending on the imaging method used. For example, the diameter was found to be 5.04 ± 0.74 mm using ultrasound, but 5.68 ± 1.19 mm using angiography. [WP,unvetted].[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Renal_artery"} xref: UMLS:C0035065 [Term] id: UBERON:0001185 name: right renal artery def: "Renal artery that supplies the right kidney" [UBERON:cjm] comment: The right [renal artery] passes behind the inferior vena cava, the right renal vein, the head of the pancreas, and the descending part of the duodenum[WP] subset: uberon_slim synonym: "right renal arterial tree" EXACT [] xref: FMA:14752 ! Right renal artery xref: MA:0002037 ! right renal artery xref: OpenCyc:Mx4rtW8I0KgEEdudWQACs5b6Bw xref: ncithesaurus:Right_Renal_Artery ! Right Renal Artery xref: OpenCyc:Mx4rtW8I0KgEEdudWQACs5b6Bw ! right renal artery xref: OpenCyc:Mx8Ngh4rvgHsHZwpEbGdrcN5Y29ycB4rveOFHpwpEbGdrcN5Y29ycA ! right renal artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Gray1120.png/200px-Gray1120.png intersection_of: UBERON:0001184 ! renal artery intersection_of: supplies UBERON:0004539 ! right kidney xref: SCTID:36800007 ! Entire right renal artery xref: UMLS:C0226332 [Term] id: UBERON:0001186 name: left renal artery def: "Renal artery that supplies the left kidney" [UBERON:cjm] comment: The left [renal artery] is somewhat higher than the right; it lies behind the left renal vein, the body of the pancreas and the splenic vein, and is crossed by the inferior mesenteric vein[WP] synonym: "left renal arterial tree" EXACT [] xref: FMA:14753 ! Left renal artery xref: MA:0002036 ! left renal artery xref: OpenCyc:Mx4rtW8I0agEEdudWQACs5b6Bw xref: ncithesaurus:Left_Renal_Artery ! Left Renal Artery xref: OpenCyc:Mx4rtW8I0agEEdudWQACs5b6Bw ! left renal artery xref: OpenCyc:Mx8Ngh4rvgIFoJwpEbGdrcN5Y29ycB4rveOFHpwpEbGdrcN5Y29ycA ! left renal artery intersection_of: UBERON:0001184 ! renal artery intersection_of: supplies UBERON:0004538 ! left kidney xref: SCTID:19215005 ! Entire left renal artery xref: UMLS:C0226333 [Term] id: UBERON:0010192 ! genital artery name: genital artery def: "One of the laterally paired arteries that supply the gonads." [ISBN10:0073040584, Wikipedia:Gonadal_artery] synonym: "gonadal artery" EXACT [] intersection_of: UBERON:0004573 ! systemic artery intersection_of: supplies UBERON:0000991 ! gonad relationship: branch_of UBERON:0001516 {source="Wikipedia"} ! abdominal aorta [Term] id: UBERON:0001187 name: testicular artery def: "The testicular artery (the male gonadal artery, also called the internal spermatic arteries in older texts) is a branch of the abdominal aorta that supplies blood to the testis. It is a paired artery, with one for each of the testes. It is the male equivalent of the ovarian artery. Because the testis is found in a different location than that of its female equivalent, it has a different course than the ovarian artery. They are two slender vessels of considerable length, and arise from the front of the aorta a little below the renal arteries. Each passes obliquely downward and lateralward behind the peritoneum, resting on the Psoas major, the right spermatic lying in front of the inferior vena cava and behind the middle colic and ileocolic arteries and the terminal part of the ileum, the left behind the left colic and sigmoid arteries and the iliac colon. Each crosses obliquely over the ureter and the lower part of the external iliac artery to reach the abdominal inguinal ring, through which it passes, and accompanies the other constituents of the spermatic cord along the inguinal canal to the scrotum, where it becomes tortuous, and divides into several branches. Two or three of these accompany the ductus deferens, and supply the epididymis, anastomosing with the artery of the ductus deferens; others pierce the back part of the tunica albuginea, and supply the substance of the testis. The internal spermatic artery supplies one or two small branches to the ureter, and in the inguinal canal gives one or two twigs to the Cremaster. [WP,unvetted]." [Wikipedia:Testicular_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "testicular arterial tree" EXACT [] xref: FMA:14758 ! Testicular artery xref: MA:0002063 ! testicular artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/af/Gray531.png/200px-Gray531.png xref: EMAPA:18621 ! testicular artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000473 ! testicle xref: SCTID:244281003 ! Entire testicular artery synonym: "arteria testicularis" RELATED LATIN [Wikipedia:Testicular_artery] xref: http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png [Term] id: UBERON:0004533 ! left testicle name: left testicle def: "A testis that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "left testis" EXACT [MA:0001746] xref: FMA:7212 ! Left testis xref: MA:0001746 ! left testis xref: ncithesaurus:Left_Testis ! Left Testis intersection_of: UBERON:0000473 ! testis intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:367720001 ! Entire left testis xref: UMLS:C0227998 [Term] id: UBERON:0004534 ! right testicle name: right testicle def: "A testis that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "right testis" EXACT [MA:0001747] xref: FMA:7211 ! Right testis xref: MA:0001747 ! right testis xref: OpenCyc:Mx4rvVjM25wpEbGdrcN5Y29ycA xref: ncithesaurus:Right_Testis ! Right Testis intersection_of: UBERON:0000473 ! testis intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:367719007 ! Entire right testis xref: UMLS:C0227997 [Term] id: UBERON:0001189 name: left testicular artery comment: This class was created automatically from a combination of ontologies synonym: "left spermatic artery" EXACT [] synonym: "trunk of left testicular arterial tree" EXACT [] xref: FMA:14760 ! Left testicular artery xref: MA:0002041 ! left spermatic artery xref: ncithesaurus:Left_Spermatic_Artery ! Left Spermatic Artery intersection_of: UBERON:0001187 ! testicular artery intersection_of: supplies UBERON:0004533 ! left testicle relationship: supplies UBERON:0001223 ! left ureter def: "A testicular artery that supplies a left testicle." [OBOL:automatic] xref: UMLS:C0734077 [Term] id: UBERON:0001188 name: right testicular artery comment: This class was created automatically from a combination of ontologies synonym: "right spermatic artery" EXACT [] synonym: "trunk of right testicular arterial tree" EXACT [] xref: FMA:14759 ! Right testicular artery xref: MA:0002042 ! right spermatic artery xref: ncithesaurus:Right_Spermatic_Artery ! Right Spermatic Artery intersection_of: UBERON:0001187 ! testicular artery intersection_of: supplies UBERON:0004534 ! right testicle relationship: supplies UBERON:0001222 ! right ureter def: "A testicular artery that supplies a right testicle." [OBOL:automatic] xref: UMLS:C0734076 [Term] id: UBERON:0001190 name: ovarian artery def: "In human anatomy, the ovarian artery is a blood vessel that supplies oxygenated blood to the ovary. It arises from the abdominal aorta below the renal artery, and does not pass out of the abdominal cavity. It can be found in the suspensory ligament of the ovary. [WP,unvetted]." [Wikipedia:Ovarian_artery] subset: uberon_slim synonym: "ovarian arterial tree" EXACT [] xref: FMA:14761 ! Ovarian artery xref: MA:0002012 ! ovarian artery xref: ncithesaurus:Ovarian_Artery ! Ovarian Artery xref: OpenCyc:Mx4rwOa9PZwpEbGdrcN5Y29ycA ! ovarian artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ae/Gray1170.png/200px-Gray1170.png xref: EMAPA:18620 ! ovarian artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000992 ! female gonad xref: SCTID:244280002 ! Entire ovarian artery synonym: "arteria ovarica" RELATED LATIN [Wikipedia:Ovarian_artery] xref: http://upload.wikimedia.org/wikipedia/commons/a/ae/Gray1170.png xref: UMLS:C0226411 [Term] id: UBERON:0009659 name: spermatic artery comment: add child terms is_a: UBERON:0010192 ! genital artery xref: MA:0002040 ! spermatic artery xref: ncithesaurus:Spermatic_Artery ! Spermatic Artery xref: UMLS:C0226409 [Term] id: UBERON:0001192 name: left gastric artery def: "In human anatomy, the left gastric artery arises from the celiac artery, and runs along the superior portion of the lesser curvature of the stomach. Branches also supply the lower esophagus. The left gastric artery anastomoses with the right gastric artery, which supplies the inferior portion. [WP,unvetted]." [Wikipedia:Left_gastric_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "gastric artery" EXACT [] xref: FMA:14768 ! Left gastric artery xref: galen:LeftGastricArtery xref: MA:0001961 ! gastric artery xref: ncithesaurus:Gastric_Artery ! Gastric Artery xref: OpenCyc:Mx4rwMjqKZwpEbGdrcN5Y29ycA ! left gastric artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Gray532.png/200px-Gray532.png is_a: UBERON:0001637 ! artery relationship: part_of UBERON:0001640 ! celiac artery relationship: supplies UBERON:0000945 ! stomach xref: SCTID:244267000 ! Entire left gastric artery synonym: "arteria gastrica sinistra" RELATED LATIN [Wikipedia:Left_gastric_artery] xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png xref: UMLS:C0226299 [Term] id: UBERON:0001193 name: hepatic artery def: "An artery that supplies the liver." [UBERON:cjm, Wikipedia:Hepatic_artery_proper] synonym: "arteria hepatica propria" EXACT LATIN [] comment: Usage notes: currently defined in a generic fashion. subset: uberon_slim subset: vertebrate_core xref: FMA:14769 ! Hepatic artery xref: GAID:496 ! hepatic artery xref: galen:HepaticArtery xref: MA:0001963 ! hepatic artery xref: ZFA:0005161 ! hepatic artery xref: ncithesaurus:Hepatic_Artery ! Hepatic Artery xref: OpenCyc:Mx4rvzKtFpwpEbGdrcN5Y29ycA ! hepatic artery xref: BTO:0004307 ! hepatic artery xref: EMAPA:17859 ! hepatic artery xref: MESH:A07.231.114.407 ! hepatic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002107 ! liver xref: SCTID:76015000 ! Hepatic artery xref: TAO:0005161 ! hepatic artery xref: http://upload.wikimedia.org/wikipedia/commons/4/4c/Common_and_proper_hepatic_artery.png property_value: external_definition "Artery that supplies blood to the liver.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005161", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0019145 [Term] id: UBERON:0001194 name: splenic artery def: "In anatomy, the splenic artery (in the past called the lienal artery) is the blood vessel that supplies oxygenated blood to the spleen. It branches from the celiac artery, and follows a course superior to the pancreas. [WP,unvetted]." [Wikipedia:Splenic_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lienal artery" EXACT [MA:0001991] synonym: "arteria splenica" EXACT LATIN [Wikipedia:Splenic_artery] synonym: "arteria lienalis" RELATED LATIN [Wikipedia:Splenic_artery] xref: FMA:14773 ! Splenic artery xref: GAID:510 ! splenic artery xref: MA:0001991 ! lienal artery xref: OpenCyc:Mx4rv0cb2ZwpEbGdrcN5Y29ycA xref: ncithesaurus:Splenic_Artery ! Splenic Artery xref: galen:SplenicArtery ! splenic artery xref: OpenCyc:Mx4rv0cb2ZwpEbGdrcN5Y29ycA ! lienal artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a2/Gray1188.png/200px-Gray1188.png xref: EMAPA:19216 ! splenic artery xref: MESH:A07.231.114.814 ! splenic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002106 ! spleen relationship: branch_of UBERON:0001640 ! celiac artery xref: SCTID:244266009 ! Entire splenic artery xref: http://upload.wikimedia.org/wikipedia/commons/a/a2/Gray1188.png xref: UMLS:C0037996 [Term] id: UBERON:0001196 name: middle colic artery def: "The middle colic artery is a branch of the superior mesenteric artery that mostly supplies the transverse colon. It arises just below the pancreas, and, passing downward and forward between the layers of the transverse mesocolon, divides into two branches: right and left. The right branch anastomoses with the right colic artery The left branch anastomoses with the left colic artery, a branch of the inferior mesenteric artery. The arches thus formed are placed about two fingers’ breadth from the transverse colon, to which they distribute branches. [WP,unvetted]." [Wikipedia:Middle_colic_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:14810 ! Middle colic artery xref: MA:0002007 ! middle colic artery xref: ncithesaurus:Middle_Colic_Artery ! Middle Colic Artery xref: galen:MiddleColicArtery ! middle colic artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Gray537.png/200px-Gray537.png is_a: UBERON:0001637 ! artery relationship: part_of UBERON:0001182 ! superior mesenteric artery relationship: supplies UBERON:0000059 ! large intestine xref: SCTID:244276007 ! Entire middle colic artery synonym: "arteria colica media" RELATED LATIN [Wikipedia:Middle_colic_artery] xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Gray537.png xref: UMLS:C0226328 [Term] id: UBERON:0001197 name: ileocolic artery def: "The Ileocolic Artery is the lowest branch arising from the concavity of the superior mesenteric artery. It passes downward and to the right behind the peritoneum toward the right iliac fossa, where it divides into a superior and an inferior branch; the inferior anastomoses with the end of the superior mesenteric artery, the superior with the right colic artery. Supplies the cecum, ileum, and appendix. [WP,unvetted]." [Wikipedia:Ileocolic_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:14815 ! Ileocolic artery xref: galen:IleocolicArtery xref: MA:0001970 ! ileocolic artery is_a: UBERON:0001637 ! artery relationship: part_of UBERON:0001182 ! superior mesenteric artery xref: ncithesaurus:Ileo-colic_Artery ! Ileo-Colic Artery xref: SCTID:244279000 ! Entire ileocolic artery synonym: "arteria ileocolica" RELATED LATIN [Wikipedia:Ileocolic_artery] xref: http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray536.png xref: UMLS:C0226323 [Term] id: UBERON:0001198 name: superior suprarenal artery def: "Each (left and right) superior suprarenal artery is a branch of the inferior phrenic artery on that side of the body. The left and right phrenic arteries supply the diaphragm, and come off the aorta. [WP,unvetted]." [Wikipedia:Superior_suprarenal_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "superior adrenal branch of inferior phrenic artery" EXACT [] synonym: "superior suprarenal branch of inferior phrenic artery" EXACT [] synonym: "arteriae suprarenales superiores" EXACT LATIN [Wikipedia:Superior_suprarenal_artery] xref: FMA:14863 ! Superior suprarenal artery xref: MA:0002057 ! superior suprarenal artery xref: ncithesaurus:Superior_Suprarenal_Artery ! Superior Suprarenal Artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/61/Gray1121.png/200px-Gray1121.png is_a: UBERON:0005624 ! suprarenal artery relationship: branch_of UBERON:0012255 ! inferior phrenic artery xref: SCTID:303424001 ! Entire superior suprarenal artery xref: http://upload.wikimedia.org/wikipedia/commons/6/61/Gray1121.png xref: UMLS:C0580876 [Term] id: UBERON:0001199 name: mucosa of stomach def: "The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits. In men it is about 1 mm thick and its surface is smooth, soft, and velvety. It consists of epithelium, lamina propria, and the muscularis mucosae. In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the organ it is thrown into numerous plaits or rugae, which, for the most part, have a longitudinal direction, and are most marked toward the pyloric end of the stomach, and along the greater curvature. These folds are entirely obliterated when the organ becomes distended. When examined with a lens, the inner surface of the mucous membrane presents a peculiar honeycomb appearance from being covered with funnel-like depressions or foveolae of a polygonal or hexagonal form, which vary from 0.12 to 0.25 mm. in diameter. These are the ducts of the gastric glands, and at the bottom of each may be seen one or more minute orifices, the openings of the gland tubes. Gastric glands are simple or branched tubular glands that emerge on the deeper part of the gastric foveola, inside the gastric areas and outlined by the folds of the mucosa. There are three types of glands: cardiac glands (in the proximal part of the stomach), oxyntic glands (the dominating type of gland), and pyloric glands. The cardiac glands mainly contain mucus producing cells. The bottom part of the oxyntic glands is dominated by zymogen (chief) cells that produce pepsinogen (an inactive precursor of the pepsin enzyme). Parietal cells, which secrete hydrochloric acid are scattered in the glands, with most of them in the middle part. The upper part of the glands consist of mucous neck cells; in this part the dividing cells are seen. The pyloric glands contain mucus-secreting cells. Several types of endocrine cells are found in all regions of the gastric mucosa. In the pyloric glands contain gastrin producing cells (G cells); this hormone stimulates acid production from the parietal cells. ECL (enterochromaffine-like) cells, found in the oxyntic glands release histamine, which also is a powerful stimulant of the acid secretion. The A cells produce glucagon, which mobilizes the hepatic glycogen, and the enterochromaffin cells that produce serotonin, which stimulates the contraction of the smooth muscles. The surface of the mucous membrane is covered by a single layer of columnar epithelium . This epithelium commences very abruptly at the cardiac orifice, where there is a sudden transition from the stratified epithelium of the esophagus. The epithelial lining of the gland ducts is of the same character and is continuous with the general epithelial lining of the stomach. [WP,unvetted]." [Wikipedia:Gastric_mucosa] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "gastric mucosa" EXACT [] synonym: "gastric mucous membrane" EXACT [] synonym: "mucous membrane of stomach" EXACT [] synonym: "stomach mucosa" EXACT [] synonym: "tunica mucosa (gaster)" EXACT [] synonym: "mucosa of organ of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of ventriculus" EXACT [OBOL:automatic] synonym: "mucosa of ventriculus" EXACT [OBOL:automatic] synonym: "mucous membrane of ventriculus" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of ventriculus" EXACT [OBOL:automatic] synonym: "stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach mucous membrane" EXACT [OBOL:automatic] synonym: "stomach organ mucosa" EXACT [OBOL:automatic] synonym: "ventriculus mucosa" EXACT [OBOL:automatic] synonym: "ventriculus mucosa of organ" EXACT [OBOL:automatic] synonym: "ventriculus mucous membrane" EXACT [OBOL:automatic] synonym: "ventriculus organ mucosa" EXACT [OBOL:automatic] synonym: "Magenschleimhaut" RELATED [BTO:0001308] synonym: "tunica mucosa gastris" RELATED [BTO:0001308] xref: BTO:0001308 xref: FMA:14907 ! Mucosa of stomach xref: GAID:321 ! gastric mucosa xref: galen:GastricMucosa xref: MA:0002683 ! stomach mucosa xref: ncithesaurus:Gastric_Mucosa ! Gastric Mucosa xref: OpenCyc:Mx8NhB4rvcD6KJwpEbGdrcN5Y29ycB4rvmKNOpwpEbGdrcN5Y29ycB4rvVj5FpwpEbGdrcN5Y29ycB4rvVjlqpwpEbGdrcN5Y29ycA ! gastric mucosa xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Illu_stomach2.jpg/200px-Illu_stomach2.jpg xref: MESH:A03.492.766.440 ! gastric mucosa is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0001167 ! wall of stomach relationship: capable_of GO:0001696 ! gastric acid secretion synonym: "tunica mucosa gastricae" EXACT LATIN [FMA:TA, FMA:14907] xref: SCTID:362131005 ! Entire gastric mucous membrane synonym: "tunica mucosa gastris" RELATED LATIN [Wikipedia:Gastric_mucosa] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Illu_stomach2.jpg xref: UMLS:C0017136 [Term] id: UBERON:0001200 name: submucosa of stomach def: "A submucosa that is part of a stomach [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "gastric submucosa" EXACT [] synonym: "stomach submucosa" EXACT [] synonym: "tela submucosa (gaster)" EXACT [] synonym: "submucosa of ventriculus" EXACT [OBOL:automatic] synonym: "ventriculus submucosa" EXACT [OBOL:automatic] xref: FMA:14908 ! Submucosa of stomach xref: MA:0002685 ! stomach submucosa xref: ncithesaurus:Gastric_Submucosa ! Gastric Submucosa xref: BTO:0002110 ! tela submucosa gastris is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0001167 ! wall of stomach xref: SCTID:52459002 ! Gastric submucosa xref: UMLS:C0227211 [Term] id: UBERON:0001201 name: serosa of stomach def: "A serous membrane that is part of a wall of stomach [Automatically generated definition]." [OBOL:automatic] comment: TODO - check serosa/peritoneum synonym: "gastric serosa" RELATED [] synonym: "serous coat of stomach" EXACT [] synonym: "stomach serosa" EXACT [] synonym: "tunica serosa (gaster)" EXACT [] synonym: "visceral peritoneum of stomach" EXACT [] synonym: "gastric wall serosa" EXACT [OBOL:automatic] synonym: "gastric wall serous membrane" EXACT [OBOL:automatic] synonym: "serosa of gastric wall" EXACT [OBOL:automatic] synonym: "serosa of stomach wall" EXACT [OBOL:automatic] synonym: "serosa of wall of stomach" EXACT [OBOL:automatic] synonym: "serous membrane of gastric wall" EXACT [OBOL:automatic] synonym: "serous membrane of stomach wall" EXACT [OBOL:automatic] synonym: "serous membrane of wall of stomach" EXACT [OBOL:automatic] synonym: "stomach wall serosa" EXACT [OBOL:automatic] synonym: "stomach wall serous membrane" EXACT [OBOL:automatic] synonym: "wall of stomach serosa" EXACT [OBOL:automatic] synonym: "wall of stomach serous membrane" EXACT [OBOL:automatic] synonym: "anatomical wall of stomach serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of stomach serous membrane" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus serous membrane" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "serosa of stomach anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of ventriculus wall" EXACT [OBOL:automatic] synonym: "serosa of wall of ventriculus" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "serous membrane of stomach anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of ventriculus wall" EXACT [OBOL:automatic] synonym: "serous membrane of wall of ventriculus" EXACT [OBOL:automatic] synonym: "stomach anatomical wall serosa" EXACT [OBOL:automatic] synonym: "stomach anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "ventriculus anatomical wall serosa" EXACT [OBOL:automatic] synonym: "ventriculus anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "ventriculus wall serosa" EXACT [OBOL:automatic] synonym: "ventriculus wall serous membrane" EXACT [OBOL:automatic] synonym: "wall of ventriculus serosa" EXACT [OBOL:automatic] synonym: "wall of ventriculus serous membrane" EXACT [OBOL:automatic] xref: FMA:14914 ! Serosa of stomach xref: MA:0001626 ! stomach serosa is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001167 ! wall of stomach relationship: part_of UBERON:0001167 ! wall of stomach synonym: "tunica serosa gastricae" EXACT LATIN [FMA:TA, FMA:14914] xref: SCTID:1353004 ! Gastric serosa xref: ncithesaurus:Gastric_Serosal_Surface ! gastric serosal surface xref: UMLS:C1517453 [Term] id: UBERON:0001203 name: muscularis mucosae of stomach comment: This class was created automatically from a combination of ontologies synonym: "lamina muscularis mucosae (tunica mucosa)(gaster)" EXACT [] synonym: "lamina muscularis of gastric mucosa" EXACT [] synonym: "muscular coat of stomach" EXACT [] synonym: "stomach muscularis mucosa" EXACT [] synonym: "gastric muscularis mucosa" EXACT [] xref: FMA:14924 ! Muscularis mucosae of stomach xref: MA:0002684 ! stomach muscularis mucosa intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0001199 ! mucosa of stomach synonym: "tunica muscularis gastricae" EXACT LATIN [FMA:TA, FMA:14924] xref: SCTID:64551004 ! Lamina muscularis of gastric mucosa xref: ncithesaurus:Gastric_Muscularis_Mucosa ! gastric muscularis mucosa def: "A muscularis mucosa that is part of a mucosa of stomach." [OBOL:automatic] xref: UMLS:C0227200 [Term] id: UBERON:0001204 name: mucosa of small intestine def: "A mucosa that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "mucous membrane of small intestine" EXACT [] synonym: "small intestinal mucosa" EXACT [] synonym: "small intestine mucosa" EXACT [] synonym: "small intestine mucous membrane" EXACT [] synonym: "tunica mucosa (intestinum tenue)" EXACT [] synonym: "mucosa of organ of small bowel" EXACT [OBOL:automatic] synonym: "mucosa of organ of small intestine" EXACT [OBOL:automatic] synonym: "mucosa of small bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of small bowel" EXACT [OBOL:automatic] synonym: "organ mucosa of small bowel" EXACT [OBOL:automatic] synonym: "organ mucosa of small intestine" EXACT [OBOL:automatic] synonym: "small bowel mucosa" EXACT [OBOL:automatic] synonym: "small bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "small bowel mucous membrane" EXACT [OBOL:automatic] synonym: "small bowel organ mucosa" EXACT [OBOL:automatic] synonym: "small intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "small intestine organ mucosa" EXACT [OBOL:automatic] xref: BTO:0001259 xref: FMA:14933 ! Mucosa of small intestine xref: MA:0002686 ! small intestine mucosa xref: ncithesaurus:Small_Intestinal_Mucosa ! Small Intestinal Mucosa is_a: UBERON:0001242 ! intestinal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 ! wall of small intestine relationship: part_of UBERON:0001242 ! intestinal mucosa synonym: "tunica mucosa intestini tenuis" EXACT LATIN [FMA:TA, FMA:14933] xref: SCTID:362144000 ! Entire small intestine mucous membrane xref: UMLS:C0227261 [Term] id: UBERON:0001205 name: submucosa of small intestine def: "submucosal tissue in the small intestines." [Wikipedia:Small_intestinal_submucosa] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "small intestinal submucosa" EXACT [] synonym: "small intestine submucosa" EXACT [] synonym: "tela submucosa (intestinum tenue)" EXACT [] synonym: "small bowel submucosa" EXACT [OBOL:automatic] synonym: "submucosa of small bowel" EXACT [OBOL:automatic] synonym: "tela submucosa intestini tenuis" EXACT LATIN [BTO:0002112] xref: FMA:14934 ! Submucosa of small intestine xref: MA:0001562 ! small intestine submucosa xref: ncithesaurus:Small_Intestinal_Submucosa ! Small Intestinal Submucosa is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 ! wall of small intestine xref: SCTID:691000 ! Small intestine submucosa xref: BTO:0002112 ! tela submucosa intestini tenuis xref: UMLS:C0227268 [Term] id: UBERON:0001206 name: serosa of small intestine def: "A serous membrane that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] comment: Histology notes: duodenum, 1st part serosa, 2nd - 4th adventitia synonym: "serous coat of small intestine" EXACT [] synonym: "small intestinal serosa" EXACT [] synonym: "small intestine serosa" EXACT [] synonym: "tunica serosa (intestinum tenue)" EXACT [] synonym: "visceral peritoneum of small intestine" EXACT [] synonym: "serosa of small bowel" EXACT [OBOL:automatic] synonym: "serous membrane of small bowel" EXACT [OBOL:automatic] synonym: "serous membrane of small intestine" EXACT [OBOL:automatic] synonym: "small bowel serosa" EXACT [OBOL:automatic] synonym: "small bowel serous membrane" EXACT [OBOL:automatic] synonym: "small intestine serous membrane" EXACT [OBOL:automatic] xref: FMA:14938 ! Serosa of small intestine xref: MA:0001558 ! small intestine serosa is_a: UBERON:0001243 ! serosa of intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 ! wall of small intestine relationship: part_of UBERON:0001243 ! serosa of intestine synonym: "tunica serosa intestini tenuis" EXACT LATIN [FMA:TA, FMA:14938] xref: SCTID:8266009 ! Small intestine serosa [Term] id: UBERON:0001207 name: mucosa of large intestine def: "A mucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "large intestinal mucosa" EXACT [] synonym: "large intestine mucosa" EXACT [] synonym: "mucous membrane of large intestine" EXACT [] synonym: "large intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "large intestine mucous membrane" EXACT [OBOL:automatic] synonym: "large intestine organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of large intestine" EXACT [OBOL:automatic] synonym: "organ mucosa of large intestine" EXACT [OBOL:automatic] xref: FMA:14969 ! Mucosa of large intestine xref: MA:0002688 ! large intestine mucosa xref: ncithesaurus:Large_Intestinal_Mucosa ! Large Intestinal Mucosa is_a: UBERON:0001242 ! intestinal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 ! wall of large intestine relationship: part_of UBERON:0001242 ! intestinal mucosa synonym: "tunica mucosa intestini crassi" EXACT LATIN [FMA:TA, FMA:14969] xref: UMLS:C0734203 [Term] id: UBERON:0001208 name: submucosa of large intestine def: "A submucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "large intestinal submucosa" EXACT [] synonym: "large intestine submucosa" EXACT [] xref: FMA:14970 ! Submucosa of large intestine xref: MA:0002690 ! large intestine submucosa xref: ncithesaurus:Large_Intestinal_Submucosa ! Large Intestinal Submucosa xref: BTO:0002111 ! tela submucosa intestini crassi is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 ! wall of large intestine xref: UMLS:C0734204 [Term] id: UBERON:0001209 name: serosa of large intestine def: "A serous membrane that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] comment: TODO - check serosa/peritoneum synonym: "large intestinal serosa" EXACT [] synonym: "large intestine serosa" EXACT [] synonym: "serous coat of large intestine" EXACT [] synonym: "visceral peritoneum of large intestine" EXACT [] synonym: "large intestine serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of large intestine" EXACT [OBOL:automatic] xref: FMA:14975 ! Serosa of large intestine xref: MA:0001546 ! large intestine serosa xref: ncithesaurus:Large_Intestinal_Serosal_Surface ! large intestinal serosal surface is_a: UBERON:0001243 ! serosa of intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 ! wall of large intestine relationship: part_of UBERON:0001243 ! serosa of intestine synonym: "tunica serosa intestini crassi" EXACT LATIN [FMA:TA, FMA:14975] xref: UMLS:C1517727 [Term] id: UBERON:0001210 name: muscularis mucosae of small intestine comment: This class was created automatically from a combination of ontologies synonym: "lamina muscularis mucosae (tunica mucosa)(intestinum tenue)" EXACT [] synonym: "lamina muscularis of small intestine mucous membrane" EXACT [] synonym: "small intestine muscularis mucosa" EXACT [] xref: FMA:15051 ! Muscularis mucosae of small intestine xref: MA:0002687 ! small intestine muscularis mucosa xref: ncithesaurus:Small_Intestinal_Muscularis_Mucosa ! Small Intestinal Muscularis Mucosa intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001204 ! mucosa of small intestine relationship: part_of UBERON:0001240 ! muscularis mucosae of intestine xref: SCTID:36401004 ! Lamina muscularis of small intestine mucous membrane def: "A muscularis mucosa that is part of a small intestine." [OBOL:automatic] xref: UMLS:C0227262 [Term] id: UBERON:0012494 name: muscularis mucosae of duodenum synonym: "lamina muscularis of duodenal mucous membrane" EXACT [FMA:15059] synonym: "lamina muscularis of duodenum" EXACT [] intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0002114 ! duodenum is_a: UBERON:0006676 {source="FMA"} ! muscularis mucosa relationship: part_of UBERON:0000320 {source="FMA"} ! duodenal mucosa xref: FMA:15059 ! muscularis mucosae of duodenum xref: EMAPA:27259 ! muscularis mucosa of mucosa of duodenum of gut xref: SCTID:37457002 ! Lamina muscularis of duodenal mucous membrane [Term] id: UBERON:0012497 name: muscularis mucosae of rectum synonym: "lamina muscularis of rectal mucosa" EXACT [FMA:15687] synonym: "lamina muscularis of rectal mucous membrane" EXACT [FMA:15687] intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0003346 {source="FMA"} ! mucosa of rectum xref: FMA:15687 ! muscularis mucosae of rectum xref: EMAPA:27343 ! muscularis mucosa of mucosa of rectum of gut xref: SCTID:53420003 ! Lamina muscularis of rectal mucous membrane [Term] id: UBERON:0001212 name: duodenal gland def: "compound tubular submucosal glands found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]." [Wikipedia:Brunner's_glands] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "Brunner's gland" EXACT [FMA:15060] synonym: "gland of Brunner" EXACT [FMA:15060] synonym: "glandula duodenales" RELATED [BTO:0002376] synonym: "glandula duodenales Brunneri" RELATED [BTO:0002376] xref: FMA:15060 ! Duodenal gland xref: GAID:314 ! brunner's gland xref: MA:0001551 ! brunner's gland xref: ncithesaurus:Brunner_s_Gland ! Brunner's Gland xref: BTO:0002376 ! duodenal gland xref: MESH:A03.492.411.620.270.322 ! brunner's gland is_a: UBERON:0011148 {notes="compound tubular"} ! submucosal gland relationship: secretes UBERON:0000912 ! mucus relationship: part_of UBERON:0002330 {source="MA-inferred"} ! exocrine system relationship: part_of UBERON:0003332 {source="FMA"} ! submucosa of duodenum xref: SCTID:41298001 ! Duodenal gland subset: organ_slim xref: UMLS:C0006323 [Term] id: UBERON:0001213 ! intestinal villus name: intestinal villus alt_id: UBERON:0007607 def: "Tiny, finger-like projections that protrude from the epithelial lining of the intestinal wall[WP]" [Wikipedia:Intestinal_villus] comment: Editor notes: in mammals, villi are (largely?) absent from the large intestine, so we treat this as equivalent to small intestinal villus. small/large subdivision may not make sense for all speciesi for which this is present (see ZFA). Note that VHOG quotes ISBN:978-0030223693 as suggesting there are some villi in the large intestine. AO Notes: the BTO class refers to a generic villous subset: uberon_slim subset: vertebrate_core synonym: "villus intestinalis (intestinum tenue)" EXACT [FMA:15072] synonym: "villus" EXACT [BTO:0003121] synonym: "intestinal villi" EXACT PLURAL [ZFA:0005125] synonym: "intestinal villus layer" RELATED [] synonym: "villi intestinales" EXACT PLURAL [] synonym: "enteric villi" EXACT PLURAL [HP:0011473] synonym: "enteric villous" EXACT [HP:0011473] synonym: "enteric villus" EXACT [HP:0011473] synonym: "small intestine villus" RELATED [MA:0001563] xref: FMA:15072 ! Intestinal villus xref: TAO:0005125 ! intestinal villus xref: ZFA:0005125 ! intestinal villus xref: BTO:0003121 ! villus xref: MA:0001563 ! small intestine villus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/38/Small_intestine_low_mag.jpg/200px-Small_intestine_low_mag.jpg is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0001204 {source="FMA", gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="may be present in other parts in other species"} ! mucosa of small intestine relationship: part_of UBERON:0001277 {source="ZFA"} ! intestinal epithelium xref: ncithesaurus:Villus ! Villus xref: SCTID:23230007 ! Intestinal villus synonym: "villi intestinales" RELATED LATIN [Wikipedia:Intestinal_villus] xref: http://upload.wikimedia.org/wikipedia/commons/3/38/Small_intestine_low_mag.jpg property_value: external_definition "The entire digestive tract is lined by well developed villi, which are longest in the intestinal bulb and decrease progressively in size towards the caudal end of the intestine. No crypts are present, but, the regions between the villi, the intervillus pockets, have a crypt-like function. Cells are produced in the intervillus pockets and shed from the villus tips. Crosnier et al. 2005[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005125", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C1519988 [Term] id: UBERON:0012423 name: layer of microvilli def: "A layer of microvilli, Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments[GO,modified]" [Wikipedia:Microvillus, GO:0005902] comment: AO notes: FMA class represents an individual microvillus. xref: FMA:67296 ! microvillus xref: ncithesaurus:Microvillus ! microvillus xref: MESH:A11.284.180.565 ! microvilli synonym: "microvillus" RELATED [FMA:67296] synonym: "microvilli" RELATED [MESH:A11.284.180.565] is_a: UBERON:0005162 ! multi cell component structure relationship: composed_primarily_of GO:0005902 ! microvillus xref: UMLS:C0026049 [Term] id: UBERON:0012424 name: brush border layer def: "the microvilli-covered surface of simple cuboidal epithelium and simple columnar epithelium cells found in certain locations of the body. Found in small intestine and kidney" [Wikipedia:Brush_border] comment: AO notes: FMA class represents an individual microvillus is_a: UBERON:0012423 ! layer of microvilli relationship: part_of UBERON:0000490 ! unilaminar epithelium xref: FMA:70977 ! brush border synonym: "brush border" RELATED [FMA:70977] synonym: "brush border membrane" RELATED [Wikipedia:Brush_border] [Term] id: UBERON:0012425 name: striated border microvillus layer comment: AO notes: FMA class represents an individual microvillus is_a: UBERON:0012423 ! layer of microvilli xref: FMA:70978 ! striated border synonym: "striated border" RELATED [FMA:70978] [Term] id: UBERON:0012426 name: short microvillus layer comment: AO notes: FMA class represents an individual microvillus is_a: UBERON:0012423 ! layer of microvilli xref: FMA:70979 ! short microvillus synonym: "short microvillus" RELATED [FMA:70979] [Term] id: UBERON:0012427 name: intestinal brush border synonym: "brush border microvillus later of intestine" EXACT [] intersection_of: UBERON:0012424 ! brush border layer intersection_of: part_of UBERON:0000160 ! intestine [Term] id: UBERON:0012428 name: proximal convoluted tubule brush border intersection_of: UBERON:0012424 ! brush border layer intersection_of: part_of UBERON:0001287 ! proximal convoluted tubule [Term] id: UBERON:0001214 name: pancreatic tributary of splenic vein def: "The pancreatic veins consist of several small vessels which drain the body and tail of the pancreas, and open into the trunk of the great pancreatic vein. [WP,unvetted]." [Wikipedia:Pancreatic_vein] comment: AO notes: see also MA:0002165 ! lieno-pancreatic vein subset: uberon_slim synonym: "pancreatic vein" EXACT [] xref: FMA:15388 ! Pancreatic tributary of splenic vein xref: MA:0002189 ! pancreatic vein xref: ncithesaurus:Pancreatic_Vein ! Pancreatic Vein is_a: UBERON:0002017 ! portal vein relationship: tributary_of UBERON:0003713 {source="FMA/obol"} ! splenic vein xref: SCTID:264492008 ! Entire pancreatic vein xref: UMLS:C0226743 [Term] id: UBERON:0001216 name: jejunal vein def: "The jejunal veins are tributaries of the superior mesenteric vein. [WP,unvetted]." [Wikipedia:Jejunal_veins] comment: This class was created automatically from a combination of ontologies xref: FMA:15402 ! Jejunal vein xref: MA:0002153 ! jejunal vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Gray591.png/200px-Gray591.png is_a: UBERON:0002017 {source="FMA"} ! portal vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002115 ! jejunum relationship: tributary_of UBERON:0001138 {source="FMA/obol"} ! superior mesenteric vein synonym: "venae jejunales" RELATED LATIN [Wikipedia:Jejunal_veins] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png [Term] id: UBERON:0001217 name: ileal vein xref: FMA:15405 ! Ileal vein xref: MA:0002140 ! ileal vein xref: ncithesaurus:Ileal_Vein ! Ileal Vein is_a: UBERON:0002017 ! portal vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002116 ! ileum relationship: part_of UBERON:0001138 ! superior mesenteric vein relationship: tributary_of UBERON:0001138 {source="FMA/obol"} ! superior mesenteric vein xref: UMLS:C1301431 [Term] id: UBERON:0001218 name: middle colic vein def: "The middle colic vein drains the transverse colon. It is a tributary of the superior mesenteric vein, and follows the path of its corresponding artery, the middle colic artery. [WP,unvetted]." [Wikipedia:Middle_colic_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "vena colica media (intermedia)" EXACT [] xref: FMA:15406 ! Middle colic vein xref: MA:0002181 ! middle colic vein xref: OpenCyc:Mx4rvywYIpwpEbGdrcN5Y29ycA ! middle colic vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Gray591.png/200px-Gray591.png is_a: UBERON:0002017 ! portal vein relationship: part_of UBERON:0001138 ! superior mesenteric vein relationship: tributary_of UBERON:0001138 {source="FMA/obol"} ! superior mesenteric vein xref: SCTID:9018004 ! Entire middle colic vein synonym: "vena colica media" RELATED LATIN [Wikipedia:Middle_colic_vein] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png [Term] id: UBERON:0001219 name: ileocolic vein def: "The ileocolic vein is a vein which drains the ileum, colon, and cecum. [WP,unvetted]." [Wikipedia:Ileocolic_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:15408 ! Ileocolic vein xref: MA:0002141 ! ileocolic vein xref: ncithesaurus:Ileocolic_Vein ! Ileocolic Vein is_a: UBERON:0002017 ! portal vein relationship: part_of UBERON:0001138 ! superior mesenteric vein relationship: tributary_of UBERON:0001138 {source="FMA/obol"} ! superior mesenteric vein xref: SCTID:36208008 ! Entire ileocolic vein synonym: "vena ileocolica" RELATED LATIN [Wikipedia:Ileocolic_vein] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png xref: UMLS:C0226744 [Term] id: UBERON:0001220 name: quadratus lumborum def: "The Quadratus lumborum is irregular and quadrilateral in shape, and broader below than above. [WP,unvetted]." [Wikipedia:Quadratus_lumborum_muscle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "muscle of posterior abdominal wall" EXACT [] xref: FMA:15569 ! Quadratus lumborum xref: MA:0002362 ! quadratus lumborum xref: ncithesaurus:Quadratus_Lumborum ! Quadratus Lumborum xref: OpenCyc:Mx4rvj1wcpwpEbGdrcN5Y29ycA ! quadratus lumborum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/de/Gray1124.png/200px-Gray1124.png xref: EMAPA:18524 ! quadratus lumborum is_a: UBERON:0002378 ! muscle of abdomen subset: organ_slim relationship: has_muscle_insertion UBERON:0001077 {source="dbpedia", notes="Last rib and transverse processes of lumbar vertebrae"} ! transverse process of vertebra relationship: has_muscle_insertion UBERON:0002414 {source="dbpedia", notes="Last rib and transverse processes of lumbar vertebrae"} ! lumbar vertebra relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="Last rib and transverse processes of lumbar vertebrae"} ! rib xref: http://upload.wikimedia.org/wikipedia/commons/d/de/Gray1124.png xref: UMLS:C0224380 [Term] id: UBERON:0001221 name: transversus abdominis muscle def: "The transversus abdominis muscle, also known as the transversalis muscle and transverse abdominal muscle, is a muscle layer of the anterior and lateral abdominal wall which is just deep to (layered below) the internal oblique muscle. It is thought to be a major muscle of the functional core of the human body; although some argue that due to its small cross-sectional area, it cannot generate the forces required to be a prime core stabilizer. [WP,unvetted]." [Wikipedia:Transversus_abdominis_muscle] subset: uberon_slim synonym: "musculus transversus abdominis" EXACT LATIN [FMA:TA] synonym: "transverse abdominal" EXACT [FMA:15570] synonym: "transversis abdominus" EXACT LATIN [Wikipedia:Transversus_abdominis_muscle] synonym: "transversalis" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transversalis muscle" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transverse abdominal" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transverse abdominal muscle" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transverse abdominis" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transverse abdominus" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transversus" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transversus abdominis" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transversus abdominus" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transversus abdominus muscle" RELATED [Wikipedia:Transversus_abdominis_muscle] synonym: "transverse abdominal" EXACT [] xref: EHDAA:8254 ! transversus abdominis xref: FMA:15570 ! Transversus abdominis xref: VHOG:0000845 ! transversus abdominis xref: MA:0002396 ! transversus abdominis xref: ncithesaurus:Transversus_Abdominis ! Transversus Abdominis xref: EHDAA2:0002078 ! transversus abdominis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/32/Illu_trunk_muscles.jpg/200px-Illu_trunk_muscles.jpg xref: EMAPA:18165 ! transversus abdominis xref: SCTID:244949003 ! Entire transversus abdominis muscle relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme is_a: UBERON:0002461 ! anterior abdominal wall muscle relationship: part_of UBERON:0006635 {source="VHOG"} ! anterior abdominal wall synonym: "musculus transversus abdominis" EXACT LATIN [FMA:TA, FMA:15570] synonym: "transversus abdominis" EXACT LATIN [] subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/3/32/Illu_trunk_muscles.jpg property_value: external_definition "One of a pair of transverse abdominal muscles that is the anterolateral muscle of the abdomen, lying immediately under the internal abdominal oblique. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000845", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/transversus+abdominis", source="http://bgee.unil.ch/"} property_value: homology_notes "Behind the thorax, the lateral group (of muscles in reptiles and mammals) remains essentially as for amphibians. (It breaks into three sheet-like layers: external oblique muscle, the internal oblique, and the transversus). More anteriorly, however, the ribs, now enlarged, penetrate and alter this group of muscles. The transversus is excluded from the thorax and the external and internal obliques become, respectively, the external and internal intercostal muscles, which contribute to the new function of ventilation of the lungs.[well established][VHOG]" xsd:string {external_class="VHOG:0000845", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.193", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0224378 [Term] id: UBERON:0001222 name: right ureter def: "An ureter that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies xref: FMA:15571 ! Right ureter xref: MA:0001685 ! right ureter xref: ncithesaurus:Right_Ureter ! Right Ureter intersection_of: UBERON:0000056 ! ureter intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:276251000 ! Entire right ureter xref: UMLS:C0227682 [Term] id: UBERON:0001223 name: left ureter def: "An ureter that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies xref: FMA:15572 ! Left ureter xref: MA:0001684 ! left ureter xref: ncithesaurus:Left_Ureter ! Left Ureter intersection_of: UBERON:0000056 ! ureter intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:276340002 ! Entire left ureter xref: UMLS:C0227683 [Term] id: UBERON:0001224 name: renal pelvis def: "funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]." [Wikipedia:Renal_pelvis, MP:0004194] comment: In this ontology, the renal pelvis is represented as the area of part-overlap between the kidney and the ureter subset: uberon_slim synonym: "kidney pelvis" EXACT [] synonym: "pelvis of ureter" EXACT [] synonym: "pyelum" RELATED [MP:0004194] synonym: "p. renallis" RELATED LATIN [Wikipedia:Renal_pelvis] xref: FMA:15575 ! Renal pelvis xref: GAID:426 ! kidney pelvis xref: MA:0000374 ! kidney pelvis xref: EMAPA:17948 ! pelvis xref: ncithesaurus:Renal_Pelvis ! Renal Pelvis xref: galen:RenalPelvis ! renal pelvis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Illu_kidney2.jpg/200px-Illu_kidney2.jpg xref: MESH:A05.810.453.537 ! kidney pelvis is_a: UBERON:0000063 ! organ segment disjoint_from: UBERON:0002355 ! pelvis relationship: part_of UBERON:0000056 {source="FMA"} ! ureter relationship: part_of UBERON:0002113 {source="MA"} ! kidney relationship: channels_from UBERON:0002113 ! kidney relationship: channels_into UBERON:0000056 ! ureter relationship: channel_for UBERON:0001088 ! urine xref: SCTID:362221007 ! Entire renal pelvis xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg xref: UMLS:C0227666 [Term] id: UBERON:0010533 name: metanephros cortex def: "The metanephric cortex is the outer region of the metanephros[GO]." [GO:0072214] intersection_of: UBERON:0001225 ! cortex of kidney intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0000081 {source="VHOG"} ! metanephros relationship: develops_from UBERON:0005113 ! metanephric cortex mesenchyme xref: VHOG:0000714 ! metanephros cortex [Term] id: UBERON:0005113 ! metanephric cortex mesenchyme name: metanephric cortex mesenchyme xref: EHDAA2:0001140 ! metanephros cortex is_a: UBERON:0003104 ! mesenchyme relationship: develops_from UBERON:0010531 {source="EHDAA2"} ! metanephros induced blastemal cells [Term] id: UBERON:0001225 ! cortex of kidney name: cortex of kidney def: "Region of parenchyma of kidney representing the outer portion.[FMA]" [Wikipedia:Renal_cortex, FMA:FMA] subset: uberon_slim synonym: "kidney cortex" EXACT [] synonym: "renal cortex" EXACT [] xref: BTO:0001166 xref: FMA:15581 ! Cortex of kidney xref: GAID:424 ! kidney cortex xref: galen:CortexOfKidney xref: MA:0000372 ! kidney cortex xref: ncithesaurus:Renal_Cortex ! Renal Cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/69/Illu_kidney.jpg/200px-Illu_kidney.jpg xref: EMAPA:17952 ! renal cortex xref: MESH:A05.810.453.324 ! kidney cortex is_a: UBERON:0001851 ! cortex intersection_of: UBERON:0001851 ! cortex intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0008987 {source="FMA"} ! renal parenchyma synonym: "cortex renalis" EXACT LATIN [FMA:TA, FMA:15581] xref: SCTID:362211004 ! Entire cortex of kidney xref: http://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg xref: UMLS:C0022655 [Term] id: UBERON:0006517 ! kidney calyx name: kidney calyx def: "Recesses of the kidney pelvis which divides into two wide, cup-shaped major renal calices, with each major calix subdivided into 7 to 14 minor calices. Urine empties into a minor calix from collecting tubules, then passes through the major calix, renal pelvis, and ureter to enter the urinary bladder. (From Moore, Clinically Oriented Anatomy, 3d ed, p211)" [MESH:A05.810.453.537.503] synonym: "renal calyx" EXACT [MA:0000369] synonym: "calyx" BROAD [EMAPA:18676] xref: MA:0000369 ! kidney calyx xref: MESH:A05.810.453.537.503 ! kidney calice xref: GAID:427 ! kidney calice xref: EMAPA:18676 ! calyx is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001224 ! renal pelvis xref: ncithesaurus:Renal_Calyx ! Renal Calyx xref: SCTID:276832000 ! Entire calyx xref: UMLS:C0022651 [Term] id: UBERON:0001226 name: major calyx def: "The major calyx, in the kidney, surrounds the apex of the malpighian pyramids. Urine formed in the kidney passes through a papilla at the apex into a minor calyx then into major calyx before passing through the renal pelvis into the ureter. Peristalsis of the smooth muscle originating in pace-maker cells originating in the walls of the calyces propels urine through the pelvis and ureters to the bladder. [WP,unvetted]." [Wikipedia:Major_calyx] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "major calix" EXACT [] xref: FMA:15613 ! Major calyx xref: MA:0001644 ! major calyx xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Kidney_PioM.png/200px-Kidney_PioM.png xref: EMAPA:18677 ! major is_a: UBERON:0006517 ! kidney calyx xref: SCTID:1106008 ! Entire major calyx synonym: "calices renales majores" RELATED LATIN [Wikipedia:Major_calyx] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png [Term] id: UBERON:0001227 name: minor calyx def: "The minor calyx, in the kidney, surrounds the apex of the malpighian pyramids. Urine formed in the kidney passes through a papilla at the apex into the minor calyx then into the major calyx. Peristalsis of the smooth muscle originating in pace-maker cells originating in the walls of the calyces propels urine through the pelvis and ureters to the bladder. [WP,unvetted]." [Wikipedia:Minor_calyx] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "minor calix" EXACT [] xref: FMA:15614 ! Minor calyx xref: MA:0001645 ! minor calyx xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Kidney_PioM.png/200px-Kidney_PioM.png xref: EMAPA:18678 ! minor is_a: UBERON:0006517 ! kidney calyx xref: SCTID:26293004 ! Entire minor calyx synonym: "calices renales minores" RELATED LATIN [Wikipedia:Minor_calyx] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png [Term] id: UBERON:0001228 name: renal papilla def: "In the kidney, the renal papilla is the location where the Medullary pyramids empty urine into the renal pelvis. Histologically it is marked by medullary collecting ducts converging to channel the fluid. Transitional epithelium begins to be seen. [WP,unvetted]." [Wikipedia:Renal_papilla] comment: This class was created automatically from a combination of ontologies synonym: "kidney papilla" EXACT [MP:0011303] subset: uberon_slim xref: FMA:15622 ! Renal papilla xref: MA:0002730 ! renal papilla xref: ncithesaurus:Renal_Papilla ! Renal Papilla xref: BTO:0003925 ! renal papilla xref: galen:RenalPapilla ! renal papilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Kidney_PioM.png/200px-Kidney_PioM.png xref: MESH:A05.810.453.466 ! kidney medulla (also: UBERON:0000362 'renal medulla') is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001294 ! inner medulla of kidney xref: SCTID:362214007 ! Entire renal papilla xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png xref: UMLS:C0022666 [Term] id: UBERON:0001229 ! renal corpuscle name: renal corpuscle def: "In the kidney, a renal corpuscle is the initial blood-filtering component of a nephron. It consists of two structures: a glomerulus and a Bowman's capsule[WP,unvetted]." [Wikipedia:Renal_corpuscle] comment: Together, the Bowmans capsule and the glomerulus comprise the definitive renal corpuscle. http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron subset: uberon_slim subset: vertebrate_core synonym: "kidney corpuscle" RELATED [Wikipedia:Renal_corpuscle] synonym: "corpusculum renale" EXACT LATIN [] synonym: "cortical renal corpuscle" RELATED [MA:0000376] synonym: "malphighian corpuscle" RELATED [MA:0000376] synonym: "malphigian corpuscle" EXACT [] synonym: "Malpighian corpuscle" EXACT [ZFA:0005281] synonym: "corpusculum renis" RELATED LATIN [Wikipedia:Renal_corpuscle] xref: BTO:0000333 xref: FMA:15625 ! Renal corpuscle xref: VHOG:0001262 ! renal corpuscle xref: MA:0000376 ! renal corpuscle xref: ncithesaurus:Renal_Corpuscle ! Renal Corpuscle xref: ZFA:0005281 ! renal corpuscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/22/Renal_corpuscle.svg/200px-Renal_corpuscle.svg.png xref: EV:0100385 ! renal corpuscle is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001285 ! nephron relationship: part_of UBERON:0007684 {source="FMA"} ! uriniferous tubule xref: SCTID:361329009 ! Entire renal corpuscle xref: EMAPA:28236 ! mature renal corpuscle xref: TAO:0005281 ! renal corpuscle xref: http://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg property_value: external_definition "The part of the nephron that filters blood.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005281", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated. Paired highly vascularized structures of the pronephros, responsible for blood filtration.[XAO]" xsd:string {ontology="XAO", external_class="XAO:0000146", date_retrieved="2012-11-28", source="XAO:curator"} property_value: external_definition "A mass of arterial capillaries enveloped in a capsule and attached to a tubule in the kidney[BTO]" xsd:string {ontology="BTO", external_class="BTO:0000333", date_retrieved="2012-11-28", source="BTO:curator"} xref: UMLS:C0227635 [Term] id: UBERON:0001230 name: glomerular capsule def: "The Bowman's capsule is a cup-like sac at the beginning of the tubular component of a nephron in the mammalian kidney. A glomerulus is enclosed in the sac. Fluids from blood in the glomerulus are collected in the Bowman's capsule and further processed along the nephron to form urine. This process is known as ultrafiltration. [WP,unvetted]." [Wikipedia:Bowman%27s_capsule] comment: One fold of the S-shaped body gives rise to Bowman’s capsule[GUDMAP] subset: uberon_slim subset: vertebrate_core synonym: "capsula glomerularis" EXACT LATIN [] synonym: "capsula glomeruli" RELATED LATIN [] synonym: "Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "Bowmans capsule" EXACT [KUPO:0001001] xref: FMA:15626 ! Glomerular capsule xref: MA:0001660 ! glomerular capsule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray1130.svg/200px-Gray1130.svg.png xref: ZFA:0005254 ! renal glomerular capsule xref: ZFA:0005310 ! pronephric glomerular capsule xref: BTO:0002297 ! renal glomerular capsule xref: EMAPA:27973 ! Bowman's capsule of maturing renal corpuscle xref: EMAPA:28257 ! Bowman's capsule of mature renal corpuscle xref: KUPO:0001001 ! bowmans capsule is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001229 ! renal corpuscle relationship: develops_from UBERON:0004199 ! S-shaped body relationship: has_function_in GO:0003094 {source="Wikipedia"} ! glomerular filtration xref: AAO:0010526 ! Bowman's capsule xref: SCTID:361331000 ! Entire glomerular capsule xref: ncithesaurus:Bowman_s_Capsule ! Bowman Capsule xref: TAO:0005254 ! renal glomerular capsule xref: TAO:0005310 ! pronephric glomerular capsule xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg property_value: external_definition "Anatomical structure found in the kidney consisting of an expanded end of a kidney tubule surrounding a glomerulus and is the major site of filtration.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010526", date_retrieved="2012-06-20", source="AAO:BJB"} synonym: "renal glomerular capsule" EXACT [TAO:0005254] synonym: "bowman's capsule " RELATED [TAO:0005254] synonym: "pronephric glomerular capsule" RELATED [TAO:0005310] xref: UMLS:C0524448 [Term] id: UBERON:0002015 ! kidney capsule name: kidney capsule def: "The renal capsule is a tough fibrous layer surrounding the kidney and covered in a thick layer of ' adipose tissue. It provides some protection from trauma and damage. The renal capsule relates to the other layers in the following order (moving from innermost to outermost): renal medulla renal cortex renal capsule perinephric fat (or 'perirenal fat') renal fascia paranephric fat (or 'pararenal fat') peritoneum (anteriorly), and transversalis fascia (posteriorly). [WP,unvetted]." [Wikipedia:Kidney_capsule] subset: uberon_slim synonym: "capsule of kidney" EXACT [] synonym: "fibrous capsule of kidney" EXACT [FMA:66610] synonym: "renal capsule" EXACT [GO:0072127] xref: FMA:66610 ! Fibrous capsule of kidney xref: galen:CapsuleOfKidney xref: MA:0000370 ! kidney capsule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/69/Illu_kidney.jpg/200px-Illu_kidney.jpg xref: EMAPA:18679 ! renal capsule is_a: UBERON:0002384 ! connective tissue disjoint_from: UBERON:0001230 ! glomerular capsule relationship: part_of UBERON:0002113 ! kidney xref: ncithesaurus:Renal_Capsule ! Renal Capsule xref: SCTID:243657006 ! Entire fibrous capsule of kidney xref: UMLS:C0227637 [Term] id: UBERON:0005750 name: glomerular parietal epithelium def: "A single layer of simple squamous epithelium in the glomerular capsule. Does not function in filtration[UBERON]. outer layer of the glomerular capsule composed of a single layer of simple squamous epithelium[MP]" [UBERON:cjm, MP:0011498] comment: TODO - check this. BTO has podocytes under here subset: vertebrate_core synonym: "parietal capsular epithelium" EXACT [MP:0011498] synonym: "Bowman's parietal epithelium" EXACT [MP:0011498] synonym: "parietal epithelium of Bowman's capsule" EXACT [MP:0011498] synonym: "parietal layer of Bowman's capsule" EXACT [MP:0011498] synonym: "parietal layer of Bowman capsule" EXACT [] synonym: "parietal layer of glomerular capsule" EXACT [MP:0011498] synonym: "capsular epithelium" EXACT [BTO:0002296] synonym: "parietal layer of glomerular capsule" EXACT [FMA:74272] synonym: "glomerular capsule parietal layer" EXACT [FMA:74272] synonym: "outer layer of glomerular capsule" EXACT [FMA:74272] synonym: "renal glomerular capsule epithelium" EXACT [ZFA:0005253] synonym: "parietal epithelial layer" EXACT [ZFA:0005253] xref: MA:0002605 ! glomerular parietal epithelium xref: FMA:74272 ! parietal layer of glomerular capsule xref: BTO:0002296 ! capsular epithelium xref: ZFA:0005253 ! renal glomerular capsule epithelium xref: EMAPA:27979 ! parietal epithelium xref: EMAPA:28260 ! parietal epithelium is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0004188 ! glomerular epithelium relationship: part_of UBERON:0001230 ! glomerular capsule relationship: adjacent_to UBERON:0001286 ! Bowman's space xref: TAO:0005253 ! renal glomerular capsule epithelium xref: ncithesaurus:Parietal_Layer_of_Bowman_s_Capsule ! parietal layer of bowman capsule xref: SCTID:362218005 ! Entire parietal layer of Bowman's capsule property_value: external_definition "Simple squamous epithelium that lines the capsule of the renal glomerulus.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005253", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0227645 [Term] id: UBERON:0005751 name: visceral layer of glomerular capsule def: "The inner, or visceral, layer of the renal glomerular capsule, overlying the capillaries, composed of podocytes, and separated from the outer, or parietal, layer by the capsular (Bowman's) space[BTO]. Lies just above the thickened glomerular basement membrane and is made of podocytes. Beneath the visceral layer lie the glomerular capillaries[WP]. inner layer of the glomerular capsule surrounding the capillary endothelial cells and composed of highly specialized epithelial cells (podocytes) that are separated by filtration slits; the visceral layer is separated from the outer parietal layer by the urinary space (also known as the Bowman's or capsular space)[MP]" [BTO:0001515, MP:0011497] comment: TODO - check - the BTO class 'glomerular epithelium' is the visceral layer. But GO uses 'glomerular epithelium' as the mereological sum of P+V layers subset: inconsistent_with_fma synonym: "visceral epithelium of Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "inner epithelial layer of Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "podocyte layer of Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "glomerular capsule visceral layer" EXACT [MP:0011497] synonym: "Bowman's visceral epithelium" EXACT [MP:0011497] synonym: "visceral epithelium of Bowman's capsule" EXACT [MP:0011497] synonym: "visceral layer of Bowman's capsule" EXACT [MP:0011497] synonym: "visceral layer of glomerular capsule" EXACT [MP:0011497] xref: FMA:74273 ! visceral layer of glomerular capsule xref: ncithesaurus:Visceral_Layer_of_Bowman_s_Capsule ! visceral layer of bowman capsule is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0001230 ! glomerular capsule relationship: adjacent_to UBERON:0001286 ! Bowman's space relationship: has_part CL:0000653 ! podocyte xref: SCTID:244093000 ! Entire visceral layer of Bowman's capsule xref: UMLS:C0227644 [Term] id: UBERON:0004188 name: glomerular epithelium def: "The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros." [GO:0072010] comment: TODO - check - GO says outer, BTO says inner. Make this a superclass synonym: "kidney glomerular epithelium" EXACT [MA:0002847] synonym: "epithelium of glomerulus" EXACT [] synonym: "epithelium of renal glomerulus" EXACT [] synonym: "epithelium of kidney glomerulus" EXACT [] synonym: "glomerular epithelial cell" RELATED [BTO:0001515] xref: BTO:0001515 ! glomerular epithelium xref: MA:0002847 ! kidney glomerular epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000074 ! renal glomerulus [Term] id: UBERON:0001286 ! Bowman's space name: Bowman's space def: "a narrow chalice-shaped cavity between the glomerular and capsular epithelium of the glomerular capsule of the kidney[TFD]. Between the visceral and parietal layers, into which the filtrate enters after passing through the podocytes' filtration slits[WP]. luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries[MP]" [Wikipedia:Bowman's_space, http://medical-dictionary.thefreedictionary.com/bowman's+space, MP:0011499] comment: TODO - fix ZFA subset: uberon_slim subset: vertebrate_core synonym: "bowman's space" EXACT [] synonym: "urinary space" EXACT [] synonym: "capsular space" EXACT [http://medical-dictionary.thefreedictionary.com/bowman's+space] synonym: "urinary space of renal corpuscle" EXACT [EMAPA:28263] synonym: "renal capsular space" EXACT [ZFA:0005283] synonym: "inter-glomerular space" EXACT [ZFA:0005283] synonym: "pronephric capsular space" EXACT [ZFA:0005312] synonym: "inter-glomerular space" EXACT [ZFA:0005312] synonym: "glomerular urinary space" EXACT [MP:0011499] synonym: "glomerular capsule space" EXACT [MP:0011499] xref: FMA:17676 ! Bowman's space xref: MA:0001664 ! urinary space xref: ncithesaurus:Urinary_Space ! Urinary Space xref: ZFA:0005283 ! renal capsular space xref: ZFA:0005312 ! pronephric capsular space xref: EMAPA:27985 ! urinary space of renal corpuscle of Bowman's capsule of maturing renal corpuscle xref: EMAPA:28263 ! urinary space of renal corpuscle of Bowman's capsule of mature renal corpuscle is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0001230 ! glomerular capsule xref: SCTID:244284006 ! Entire Bowman's space xref: TAO:0005283 ! renal capsular space xref: TAO:0005312 ! pronephric capsular space property_value: external_definition "Space between the renal glomerulus and the glomerular capsule. Renal filtrate collects here then passes into the renal tubule.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005283", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Space between the renal glomerulus and the glomerular capsule. Renal filtrate collects here then passes into the renal tubule.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005312", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "bowmanb%s space" RELATED [TAO:0005312] xref: UMLS:C0227643 [Term] id: UBERON:0005777 name: glomerular basement membrane def: "The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration through the filtration slits between the podocytes, separating the blood on the inside from the filtrate on the outside. It is a fusion of the endothelial cell and podocyte basal laminas." [Wikipedia:Glomerular_basement_membrane] subset: vertebrate_core synonym: "GBM" BROAD ABBREVIATION [] synonym: "glomerular filtration membrane" EXACT [ZFA:0005285] synonym: "glomerular capillary basement membrane" EXACT [MA:0001659] xref: FMA:74274 ! Glomerular basement membrane xref: ZFA:0005285 ! glomerular basement membrane xref: EMAPA:28251 ! glomerular basement membrane of glomerular tuft xref: EMAPA:30965 ! glomerular basement membrane of maturing glomerular tuft xref: MA:0001659 ! glomerular capillary basement membrane intersection_of: UBERON:0005769 ! basement membrane intersection_of: part_of UBERON:0000074 ! renal glomerulus relationship: part_of UBERON:0001229 ! renal corpuscle relationship: capable_of GO:0003094 ! glomerular filtration xref: ncithesaurus:Glomerular_Basement_Membrane ! Glomerular Basement Membrane xref: SCTID:243897006 ! Entire glomerular capillary basement membrane xref: TAO:0005285 ! glomerular basement membrane xref: http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png property_value: external_definition "Membrane between the mesonephric podocytes and the renal glomerular capillaries. It is a trilaminar structure composed of the fused basement membranes of the glomerular capillaries and basement membrane of the podocytes. The capillary membranes touch the GBM at contact points that are separated by pores. The membrane is semi-permeable allowing water and small molecules to pass into the renal capsular space.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005285", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-000824-1"} relationship: part_of UBERON:0004188 {is_inferred="true", source="reference_0000032"} ! glomerular epithelium xref: UMLS:C0599297 [Term] id: UBERON:0005787 name: lamina densa def: "Middle layer of the glomerular basement membrane." [ZFIN:curator] subset: vertebrate_core synonym: "middle layer of glomerular basement membrane" EXACT [FMA:74276] synonym: "lamina densa of glomerular basement membrane" EXACT [FMA:74276] xref: ZFA:0005286 ! lamina densa xref: FMA:74276 ! middle layer of glomerular basement membrane intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: part_of UBERON:0005777 ! glomerular basement membrane intersection_of: adjacent_to UBERON:0005789 ! lamina rara externa intersection_of: adjacent_to UBERON:0005788 ! lamina rara interna xref: ncithesaurus:Lamina_Densa ! Lamina Densa xref: TAO:0005286 ! lamina densa xref: UMLS:C1235665 [Term] id: UBERON:0005788 ! lamina rara interna name: lamina rara interna def: "Layer of the glomerular basement membrane adjacent to the glomerular capillary." [ZFIN:curator] subset: vertebrate_core synonym: "internal layer of glomerular basement membrane" EXACT [FMA:74277] synonym: "lamina interna of glomerular basement membrane" EXACT [FMA:74277] xref: ZFA:0005287 ! lamina rara interna xref: FMA:74277 ! internal layer of glomerular basement membrane intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: part_of UBERON:0005777 ! glomerular basement membrane intersection_of: adjacent_to UBERON:0001230 ! glomerular capsule xref: ncithesaurus:Lamina_Rara_Interna ! Lamina Rara Interna xref: TAO:0005287 ! lamina rara interna xref: UMLS:C1517719 [Term] id: UBERON:0005789 ! lamina rara externa name: lamina rara externa def: "Layer of the glomerular basement membrane adjacent to the podocytes and capsular space." [ZFIN:curator] subset: vertebrate_core synonym: "lamina externa of glomerular basement membrane" EXACT [FMA:74275] synonym: "external layer of glomerular basement membrane" EXACT [FMA:74275] xref: ZFA:0005288 ! lamina rara externa xref: FMA:74275 ! external layer of glomerular basement membrane intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: part_of UBERON:0005777 ! glomerular basement membrane intersection_of: adjacent_to UBERON:0001286 ! Bowman's space xref: ncithesaurus:Lamina_Rara_Externa ! Lamina Rara Externa xref: TAO:0005288 ! lamina rara externa xref: UMLS:C1517718 [Term] id: UBERON:0006553 name: renal duct def: "A tube in the kidney that collect and transport urine." [ZFIN:ZDB-PUB-071029-9] comment: in ZFA this is defined as part of mesonephros xref: ZFA:0005289 ! renal duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0002113 ! kidney xref: TAO:0005289 ! renal duct [Term] id: UBERON:0009201 ! nephric duct name: nephric duct def: "A nephric duct is a tube that drains a primitive kidney[GO]." [GO:0072176] comment: pronephric duct or mesonephric duct is_a: UBERON:0000058 ! duct is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0003060 name: pronephric duct def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]." [Wikipedia:Pronephric_duct] subset: uberon_slim synonym: "archinephric duct" RELATED [VHOG:0000082] xref: TAO:0000150 ! pronephric duct xref: XAO:0000063 ! pronephric duct xref: ZFA:0000150 ! pronephric duct xref: ncithesaurus:Pronephric_Duct ! Pronephric Duct xref: VHOG:0000082 ! archinephric duct (also: UBERON:0003074 'mesonephric duct') is_a: UBERON:0009201 {source="GO"} ! nephric duct relationship: part_of UBERON:0002120 ! pronephros relationship: develops_from UBERON:0005721 {source="XAO"} ! pronephric mesoderm relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm xref: AAO:0011088 ! pronephric duct xref: SCTID:361406002 ! Pronephric duct synonym: "ductus pronephricus" RELATED LATIN [Wikipedia:Pronephric_duct] property_value: external_definition "Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000150", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000082", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {external_class="VHOG:0000082", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1283945 [Term] id: UBERON:0003074 name: mesonephric duct def: "Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]." [Wikipedia:Mesonephric_duct, ZFIN:curator] comment: TODO - mesonephric portion of the nephric duct. Development notes: In the male the Wolffian duct persists, and forms for example the epididymis, the ductus deferens, the ejaculatory duct, seminal vesicle and efferent ducts. subset: uberon_slim subset: vertebrate_core synonym: "renal duct" RELATED [] synonym: "Wolffian duct" EXACT [Wikipedia:Wolffian_duct, ZFA:0000546, GOC:yaf] synonym: "Leydig's duct" RELATED [Wikipedia:Wolffian_duct] synonym: "archinephric duct" RELATED [Wikipedia:Wolffian_duct, VHOG:0000082] xref: EMAPA:16577 ! nephric duct xref: TAO:0000546 ! mesonephric duct xref: XAO:0000242 ! mesonephric duct xref: ZFA:0000546 ! mesonephric duct xref: GAID:1315 ! wolffian duct xref: AAO:0000637 ! Wolffian_duct xref: ncithesaurus:Mesonephric_Duct ! Mesonephric Duct xref: VHOG:0000082 ! archinephric duct (also: UBERON:0003060 'pronephric duct') xref: EHDAA2:0001243 ! nephric duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Gray1109.png/200px-Gray1109.png xref: EHDAA:1590 ! nephric duct xref: MESH:A16.254.940 ! wolffian duct is_a: UBERON:0009201 {source="GO"} ! nephric duct relationship: develops_from UBERON:0003060 ! pronephric duct relationship: part_of UBERON:0000080 ! mesonephros xref: SCTID:308800003 ! Entire mesonephric duct synonym: "ductus mesonephricus; ductus Wolffi" RELATED LATIN [Wikipedia:Mesonephric_duct] xref: http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png property_value: external_definition "Anatomical structure consisting of either of a pair of longitudinal ducts which carry urine and in males, sperm, to the cloaca.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000637", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000082", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {external_class="VHOG:0000082", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0043204 [Term] id: UBERON:0007684 name: uriniferous tubule def: "functional unit of the kidney that forms urine, consisting of two parts, the nephron and the collecting tubule." [ISBN10:0073040584 "Vertebrates\, Kardong"] xref: FMA:17691 ! uriniferous tubule is_a: UBERON:0003914 ! epithelial tube relationship: part_of UBERON:0002113 {source="FMA"} ! kidney [Term] id: UBERON:0009773 ! renal tubule name: renal tubule synonym: "renal tubule (generic)" EXACT [UBERON:cjm] synonym: "tubule of excretory system" EXACT [UBERON:cjm, OBOL:automatic] def: "A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10, GO:0061333] subset: grouping_class is_a: UBERON:0003914 ! epithelial tube relationship: part_of UBERON:0001008 ! excretory system [Term] id: UBERON:0001231 name: nephron tubule alt_id: UBERON:0004210 def: "An epithelial tube that is part of the nephron, the functional part of the kidney." [GO:0072078, Wikipedia:Renal_tubule] comment: note that in ISBN10:0073040584 "Vertebrates\, Kardong", the uriniferous tubule contains the nephron, so we have a separate class, rather than using a synonym, as in MA subset: uberon_slim subset: vertebrate_core synonym: "renal tubule" BROAD [] synonym: "tubulus renalis" EXACT [] synonym: "kidney tubule" EXACT [GAID:433] synonym: "uriniferous tubule" RELATED [MA:0000377] xref: BTO:0000343 xref: GAID:433 ! kidney tubule xref: FMA:15627 ! Renal tubule xref: MA:0000377 ! renal tubule xref: TAO:0001287 ! renal tubule xref: ZFA:0001287 ! renal tubule xref: ncithesaurus:Renal_Tubule ! Renal Tubule xref: EMAPA:27782 ! renal tubule xref: MESH:A05.810.453.736.560 ! kidney tubule xref: EV:0100387 ! renal tubule xref: EFO:0003666 ! renal tubule is_a: UBERON:0009773 {source="GO"} ! renal tubule intersection_of: UBERON:0003914 ! epithelial tube intersection_of: part_of UBERON:0001285 {source="ZFA", source="GO", source="MA"} ! nephron relationship: develops_from UBERON:0003918 {notes="checkme"} ! kidney mesenchyme relationship: has_part CL:0005009 {source="ZFA"} ! renal principal cell xref: SCTID:361332007 ! Entire renal tubule xref: UMLS:C0022674 [Term] id: UBERON:0007685 ! region of nephron tubule name: region of nephron tubule comment: note - consider moving MA:0000377 renal tubule here, as it includes the various segments (proximal etc) as subclasses, not parts synonym: "renal tubule region" EXACT [FMA:17692] xref: FMA:17692 ! region of renal tubule is_a: UBERON:0003914 ! epithelial tube relationship: part_of UBERON:0001231 ! nephron tubule synonym: "region of renal tubule" RELATED [FMA:17692] [Term] id: UBERON:0001232 ! collecting duct of renal tubule name: collecting duct of renal tubule def: "The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient" [GO:0072044, Wikipedia:Collecting_tubule] comment: note that in ISBN10:0073040584 "Vertebrates\, Kardong", the nephron is adjacent to the collecting tubule, consistent with FMA, but not GO. Wikipedia says: Many sources include the connecting tubule as part of the collecting duct system. However, the embryological origin is more similar to the nephron than it is to the rest of the collecting duct (which derives from the ureteric bud), and other sources therefore classify the connecting tubule with the nephron subset: uberon_slim subset: vertebrate_core synonym: "collecting duct" EXACT [GO:0072044] synonym: "collecting tubule" RELATED [] synonym: "kidney collecting duct" EXACT [] synonym: "renal collecting tubule" EXACT [FMA:15628] synonym: "tubulus renalis colligens" EXACT [] synonym: "collecting duct system" RELATED [BTO:0000761] synonym: "junctional tube" RELATED [Wikipedia:Connecting_tubule] synonym: "arcuate renal tubule" RELATED [Wikipedia:Connecting_tubule] synonym: "tubulus renalis arcuatus" EXACT LATIN [Wikipedia:Connecting_tubule] synonym: "kidney collecting tubule" RELATED [] xref: GAID:434 ! collecting kidney tubule xref: FMA:15628 ! Collecting duct of renal tubule xref: MA:0000371 ! kidney collecting duct xref: ZFA:0005294 ! collecting duct xref: EMAPA:28407 ! collecting duct xref: BTO:0000761 ! collecting duct xref: MESH:A05.810.453.736.560.510 ! collecting kidney tubule xref: EV:0100391 ! renal collecting duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0001285 {source="GO", notes="checkme"} ! nephron relationship: part_of UBERON:0007684 {source="FMA"} ! uriniferous tubule xref: SCTID:28202009 ! Collecting duct xref: TAO:0005294 ! collecting duct property_value: external_definition "Renal duct that collects the output from renal tubules.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005294", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0004737 name: metanephric collecting duct def: "A collecting duct of renal tubule that is part of a metanephros [Automatically generated definition]." [OBOL:automatic] synonym: "collecting duct of metanephros" EXACT [] xref: VHOG:0000983 ! metanephric collecting ducts intersection_of: UBERON:0001232 ! collecting duct of renal tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0003220 {source="Wikipedia-abduced"} ! metanephric mesenchyme synonym: "metanephric collecting tubule" RELATED [VHOG:0000983] relationship: part_of UBERON:0005110 {is_inferred="true", source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0001233 name: right adrenal gland def: "An adrenal gland that is in the right side of the abdomen" [OBOL:automatic] comment: in humans, the right adrenal gland is triangular shaped[WP] synonym: "right suprarenal gland" EXACT [] synonym: "glandula suprarenalis dexter" EXACT LATIN [] xref: FMA:15629 ! Right adrenal gland xref: MA:0000719 ! right adrenal gland xref: ncithesaurus:Right_Adrenal_Gland ! Right Adrenal Gland intersection_of: UBERON:0002369 ! adrenal gland intersection_of: in_right_side_of UBERON:0000916 ! abdomen xref: SCTID:281625001 ! Entire right adrenal gland xref: UMLS:C0229559 [Term] id: UBERON:0001234 name: left adrenal gland def: "An adrenal gland that is in the left side of the abdomen" [OBOL:automatic] comment: in humans, the left adrenal gland is semilunar shaped[WP] synonym: "left suprarenal gland" EXACT [] synonym: "glandula suprarenalis sinister" EXACT LATIN [] xref: FMA:15630 ! Left adrenal gland xref: MA:0000718 ! left adrenal gland xref: ncithesaurus:Left_Adrenal_Gland ! Left Adrenal Gland intersection_of: UBERON:0002369 ! adrenal gland intersection_of: in_left_side_of UBERON:0000916 ! abdomen xref: SCTID:281626000 ! Entire left adrenal gland xref: UMLS:C0229560 [Term] id: UBERON:0001235 ! adrenal cortex name: adrenal cortex def: "Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively. It is also a secondary site of androgen synthesis. [WP,unvetted]." [Wikipedia:Adrenal_cortex] comment: Taxon notes: Kardong states that mammals are the first to have distinct cortext and medulla, but this contradicts XAO subset: uberon_slim synonym: "adrenal gland cortex" EXACT [] synonym: "cortex (glandula suprarenalis)" EXACT [] synonym: "cortex of adrenal gland" EXACT [] synonym: "cortex of suprarenal gland" EXACT [] synonym: "suprarenal cortex" EXACT [] synonym: "suprarenal" RELATED [] synonym: "cortex glandulae suprarenalis" RELATED [BTO:0000045] xref: BTO:0000045 xref: EFO:0000237 ! adrenal cortex xref: FMA:15632 ! Adrenal cortex xref: GAID:447 ! adrenal cortex xref: VHOG:0001481 ! adrenal gland cortex xref: MA:0000118 ! adrenal gland cortex xref: MAT:0000494 ! adrenal cortex xref: ncithesaurus:Adrenal_Cortex xref: XAO:0000165 ! adrenal cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Gray1185.png/200px-Gray1185.png xref: EMAPA:18427 ! cortex xref: MESH:A06.407.071.140 ! adrenal cortex xref: EV:0100136 ! adrenal cortex is_a: UBERON:0001851 ! cortex intersection_of: UBERON:0001851 ! cortex intersection_of: part_of UBERON:0002369 ! adrenal gland relationship: part_of UBERON:0002369 ! adrenal gland relationship: develops_from UBERON:0000926 {source="Wikipedia"} ! mesoderm relationship: capable_of GO:0006705 ! mineralocorticoid synthesis relationship: capable_of GO:0006704 ! glucocorticoid biosynthetic process xref: AAO:0011009 ! adrenal cortex xref: SCTID:362584002 ! Entire adrenal cortex synonym: "cortex glandulae suprarenalis" RELATED LATIN [Wikipedia:Adrenal_cortex] xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray1185.png property_value: homology_notes "All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues (medulla), but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG]" xsd:string {external_class="VHOG:0001481", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.518 and Figure 15-9", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0001613 [Term] id: UBERON:0001236 ! adrenal medulla name: adrenal medulla def: "The adrenal medulla is part of the adrenal gland. It is located at the center of the gland, being surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine, norepinephrine, and a small amount of dopamine in response to stimulation by sympathetic preganglionic neurons. Composed mainly of hormone-producing chromaffin cells, the adrenal medulla is the principal site of the conversion of the amino acid tyrosine into the catecholamines adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine[WP,unvetted]." [Wikipedia:Adrenal_medulla] subset: uberon_slim synonym: "adrenal gland medulla" EXACT [] synonym: "chromaffin cells" RELATED [] synonym: "medulla (glandula suprarenalis)" EXACT [] synonym: "medulla of suprarenal gland" EXACT [] synonym: "suprarenal medulla" EXACT [] synonym: "medulla of adrenal gland" EXACT [OBOL:automatic] synonym: "medulla of glandula suprarenalis" RELATED [BTO:0000049] xref: BTO:0000049 xref: EFO:0000852 ! adrenal medulla xref: FMA:15633 ! Adrenal medulla xref: GAID:451 ! adrenal medulla xref: VHOG:0001378 ! adrenal medulla xref: MA:0000119 ! adrenal gland medulla xref: MAT:0000495 ! adrenal medulla xref: ncithesaurus:Adrenal_Medulla xref: XAO:0000166 ! adrenal medulla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Gray1185.png/200px-Gray1185.png xref: EMAPA:18428 ! medulla of adrenal gland xref: MESH:A06.224.161 ! chromaffin cell xref: EV:0100137 ! adrenal medulla is_a: UBERON:0000958 ! medulla intersection_of: UBERON:0000958 ! medulla intersection_of: part_of UBERON:0002369 ! adrenal gland relationship: surrounded_by UBERON:0001235 {source="Wikipedia"} ! adrenal cortex relationship: develops_from UBERON:0002342 {source="Kardong", source="UBERONREF:0000002"} ! neural crest relationship: has_part CL:0002082 {source="FMA"} ! type II cell of adrenal medulla relationship: has_part CL:0002083 {source="FMA"} ! type I cell of adrenal medulla relationship: has_part CL:1000426 ! chromaffin cell of adrenal gland synonym: "medulla glandulae suprarenalis" EXACT LATIN [FMA:TA, FMA:15633] xref: AAO:0011010 ! adrenal medulla xref: SCTID:362585001 ! Entire adrenal medulla xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray1185.png property_value: homology_notes "All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues (medulla), but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG]" xsd:string {external_class="VHOG:0001378", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.518 and Figure 15-9", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0001629 [Term] id: UBERON:0006858 ! adrenal/interrenal gland name: adrenal/interrenal gland def: "This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells[GO]" [GO:0030325] comment: Editor notes: keep this grouping class so long as it is required for GO subset: grouping_class synonym: "adrenal gland - interrenal gland" EXACT [VHOG:0001141] synonym: "adrenal gland/interrenal tissue" EXACT [] xref: VHOG:0001141 ! adrenal gland - interrenal gland (also: UBERON:0002369 'adrenal gland') (also: UBERON:0006856 'interrenal gland') is_a: UBERON:0002368 ! endocrine gland relationship: part_of UBERON:0000916 ! abdomen relationship: develops_from UBERON:0003064 ! intermediate mesoderm relationship: has_part CL:0000166 ! chromaffin cell relationship: has_part CL:0000457 ! biogenic amine secreting cell subset: organ_slim synonym: "adrenal - interrenal gland" RELATED [VHOG:0001141] synonym: "suprarenal gland - interrenal gland" RELATED [VHOG:0001141] property_value: homology_notes "All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues, but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG]" xsd:string {external_class="VHOG:0001141", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.518 and Figure 15-9", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002369 ! adrenal gland name: adrenal gland def: "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]." [Wikipedia:Adrenal_gland, BTO:0000047] comment: Taxon notes: The origin of the adrenal gland is still controversial. It is thought to share the same origin as the kidney and gonads, derived from coelomic epithelium of the urogenital ridge and/or the underlying mesenchyme (Keegan and Hammer, 2002; Morohashi, 1997). We follow Kardong and state homology at the level of the cortex and medulla rather than gland as a whole subset: uberon_slim synonym: "adrenal medulla cell" RELATED [] synonym: "suprarenal gland" RELATED [Wikipedia:Adrenal_gland] synonym: "interrenal gland" RELATED HOMOLOGY [GO:0030325] synonym: "adrenal" RELATED [BTO:0000047] synonym: "adrenal capsule" RELATED [BTO:0000047] synonym: "atrabiliary capsule" RELATED [BTO:0000047] synonym: "epinephros" RELATED [BTO:0000047] synonym: "glandula suprarenalis" RELATED [BTO:0000047] synonym: "suprarenal capsule" RELATED [BTO:0000047] synonym: "epinephric gland" RELATED [Wikipedia:Adrenal_gland] synonym: "glandula suprarenalis" EXACT LATIN [Wikipedia:Adrenal_gland] synonym: "glandula adrenalis" EXACT LATIN [Wikipedia:Adrenal_gland] xref: BTO:0000047 xref: EFO:0000238 ! adrenal gland xref: FMA:9604 ! Adrenal gland xref: GAID:446 ! adrenal gland xref: galen:AdrenalGland xref: MA:0000116 ! adrenal gland xref: MAT:0000071 ! adrenal gland xref: MIAA:0000071 ! adrenal gland xref: OpenCyc:Mx4rvXYiz5wpEbGdrcN5Y29ycA xref: XAO:0000164 ! adrenal gland xref: ncithesaurus:Adrenal_Gland ! Adrenal Gland xref: OpenCyc:Mx4rvXYiz5wpEbGdrcN5Y29ycA ! adrenal gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c6/Illu_endocrine_system.jpg/200px-Illu_endocrine_system.jpg xref: EMAPA:18426 ! adrenal gland xref: MESH:A06.407.071 ! adrenal gland xref: EV:0100135 ! adrenal gland xref: VHOG:0001141 ! adrenal gland - interrenal gland (also: UBERON:0006858 'adrenal/interrenal gland') (also: UBERON:0006856 'interrenal gland') is_a: UBERON:0006858 ! adrenal/interrenal gland relationship: has_developmental_contribution_from UBERON:0000926 {source="Wikipedia"} ! mesoderm relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest relationship: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000949 ! endocrine system xref: AAO:0010551 ! adrenal gland xref: SCTID:181127006 ! Entire adrenal gland subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/9/9d/Illu_endocrine_system_New.png property_value: external_definition "Anatomical structure which is found on the surface of the kidney and secretes various hormones including epinephrine, norephinephrine, aldosterone, corticosterone, and cortisol.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010551", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues, but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG]" xsd:string {external_class="VHOG:0001141", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.518 and Figure 15-9", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0000949 {source="FMA-abduced-lr"} ! endocrine system xref: UMLS:C0001625 [Term] id: UBERON:0006856 name: interrenal gland def: "Structures in fishes homologous to the cortical tissue of the mammalian adrenal gland; they are in close proximity to or imbedded in the head kidney." [BTO:0000808, doi:10.1242/dev.00427] comment: Editor notes: check isa - not a true gland? There are two types of interrenal cells identified (1) The noradrenaline type, which contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. (2) The adrenaline type, in which the vesicles are smaller and contain homogenous electron-lucent granules that are separated from the vesicular membrane by a visible -- halo http://dev.biologists.org/content/130/10/2107.full synonym: "interrenal tissue" RELATED [] synonym: "interrenal bodies" RELATED [] synonym: "interrenal gland" RELATED [] synonym: "interrenal body" RELATED [BTO:0000808] synonym: "interrenal" RELATED [http://dev.biologists.org/content/130/10/2107.full] xref: BTO:0000808 ! interrenal gland xref: GAID:1227 ! interrenal gland xref: ZFA:0001345 ! interrenal gland xref: MESH:A13.530 ! interrenal gland xref: VHOG:0001141 ! adrenal gland - interrenal gland (also: UBERON:0006858 'adrenal/interrenal gland') (also: UBERON:0002369 'adrenal gland') is_a: UBERON:0006858 ! adrenal/interrenal gland relationship: develops_from UBERON:0006857 {source="ZFA"} ! interrenal primordium relationship: homologous_to UBERON:0001235 {source="ZFA:0001345"} ! adrenal cortex relationship: part_of UBERON:0007132 {source="ZFA"} ! head kidney relationship: capable_of GO:0006694 {source="doi:10.1242/dev.00427"} ! steroid biosynthetic process relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002", notes="check body vs gland"} ! neural crest subset: organ_slim xref: TAO:0001345 ! interrenal gland property_value: external_definition "An epithelial structure consisting of steroid producing cells interposed with chromaffin cells embedded within the head kidney. The interrenal gland is thought to be the equivalent of the mammalian adrenal cortex in zebrafish. Hsu et al. 2003.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001345", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "All craniates have groups of cells homologous to the mammalian adrenocortical and chromaffin tissues, but they are scattered in and near the kidneys in fishes. (...) The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well established][VHOG]" xsd:string {external_class="VHOG:0001141", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.518 and Figure 15-9", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006857 ! interrenal primordium name: interrenal primordium comment: Development notes: splanchnic mesoderm adjacent to urogenital ridge. Editor notes: consider ceding to TAO/ZFA - however, structure also present in cyclostomes xref: TAO:0001346 ! interrenal primordium xref: ZFA:0001346 ! interrenal primordium is_a: UBERON:0001048 {source="Obol"} ! primordium is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0003064 ! intermediate mesoderm relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0010074 name: chromaffin system def: "The cells of the body which stain with chromium salts. They occur along the sympathetic nerves, in the adrenal gland, and in various other organs." [MESH:A06.224] comment: Taxon notes: in adult cylostomes and teleosts, the interrenal bodies are separate from chromaffin bodies synonym: "argentaffin system" RELATED [MESH:A06.224] synonym: "chromaffin tissue" RELATED [] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000949 {source="cjm"} ! endocrine system relationship: composed_primarily_of CL:0000166 ! chromaffin cell relationship: develops_from UBERON:0002342 {source="CL", source="Kardong"} ! neural crest relationship: homologous_to UBERON:0001236 {source="Kardong"} ! adrenal medulla xref: MESH:A06.224 ! chromaffin system xref: FMA:79645 ! chromaffin system [Term] id: UBERON:0012279 ! paraganglion name: paraganglion def: "Small bodies containing chromaffin cells occurring outside of the adrenal medulla, most commonly near the sympathetic ganglia and in organs such as the kidney, liver, heart and gonads." [MESH:A06.224.736, Wikipedia:Paraganglion] comment: Editors note: unrevised synonym: "chromaffin paraganglia" RELATED PLURAL [MESH:A06.224.736] synonym: "chromaffin paraganglion" RELATED [MESH:A06.224.736] synonym: "chromaffin body" RELATED [MESH:A06.224.736] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000949 {source="FMA"} ! endocrine system relationship: has_part CL:0000166 ! chromaffin cell xref: FMA:15648 ! paraganglion xref: ncithesaurus:Paraganglion ! paraganglion xref: SCTID:329735008 ! Entire paraganglion of extremity xref: EMAPA:18223 ! paraganglion of Zuckerkandl xref: MESH:A06.224.736 ! chromaffin paraganglia xref: UMLS:C0030419 xref: CALOHA:TS-2358 ! Paraganglia chromaffin [Term] id: UBERON:0001237 name: paraaortic body def: "." [Wikipedia:Organ_of_Zuckerkandl] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "organ of zuckerkandl" EXACT [] synonym: "para-aortic body" RELATED [] synonym: "paraganglia of zuckerkandl" RELATED [] synonym: "paraganglion of Zuckerkandl" EXACT [EMAPA:18223] xref: EMAPA:18223 ! paraganglion of Zuckerkandl xref: FMA:15647 ! Paraaortic body xref: GAID:444 ! para-aortic body xref: MA:0001137 ! organ of zuckerkandl xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/af/Gray531.png/200px-Gray531.png xref: MESH:A06.224.636 ! para-aortic body is_a: UBERON:0000062 {source="FMA"} ! organ relationship: part_of UBERON:0000949 ! endocrine system xref: SCTID:276159005 ! Entire paraaortic body subset: organ_slim xref: ncithesaurus:Paraaortic ! paraaortic region xref: http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png xref: UMLS:C0442134 [Term] id: UBERON:0001238 name: lamina propria of small intestine def: "Lamina propria that is part_of the small intestine." [GOC:Obol] synonym: "lamina propria mucosae of small intestine" EXACT [] synonym: "lamina propria of mucosa of small intestine" EXACT [] synonym: "small intestine lamina propria" EXACT [] synonym: "lamina propria mucosa of small bowel" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of small intestine" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of small bowel" EXACT [OBOL:automatic] synonym: "lamina propria of small bowel" EXACT [OBOL:automatic] synonym: "small bowel lamina propria" EXACT [OBOL:automatic] synonym: "small bowel lamina propria mucosa" EXACT [OBOL:automatic] synonym: "small bowel lamina propria mucosae" EXACT [OBOL:automatic] synonym: "small intestine lamina propria mucosa" EXACT [OBOL:automatic] synonym: "small intestine lamina propria mucosae" EXACT [OBOL:automatic] xref: FMA:15651 ! Lamina propria of small intestine xref: MA:0001554 ! small intestine lamina propria xref: ncithesaurus:Small_Intestinal_Lamina_Propria ! Small Intestinal Lamina Propria is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001204 ! mucosa of small intestine xref: SCTID:63588008 ! Small intestine lamina propria relationship: part_of UBERON:0001168 {source="reference_0000032"} ! wall of small intestine xref: UMLS:C1711325 [Term] id: UBERON:0011189 name: lamina propria of large intestine synonym: "lamina propria of mucosa of large intestine" EXACT [FMA:15654] synonym: "large intestine lamina propria" EXACT [FMA:15654] synonym: "large intestinal lamina propria" EXACT [] intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001207 {source="FMA"} ! mucosa of large intestine xref: FMA:15654 ! lamina propria of large intestine xref: ncithesaurus:Large_Intestinal_Lamina_Propria def: "A lamina propria that is part of a large intestine." [OBOL:automatic] relationship: part_of UBERON:0001169 {source="reference_0000032"} ! wall of large intestine xref: UMLS:C1708644 [Term] id: UBERON:0001239 name: muscularis mucosae of large intestine comment: This class was created automatically from a combination of ontologies synonym: "lamina muscularis of large intestine mucosa" EXACT [] synonym: "lamina muscularis of large intestine mucous membrane" EXACT [] synonym: "large intestine muscularis mucosa" EXACT [] xref: FMA:15655 ! Muscularis mucosae of large intestine xref: MA:0002689 ! large intestine muscularis mucosa xref: ncithesaurus:Large_Intestinal_Muscularis_Mucosa ! Large Intestinal Muscularis Mucosa intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001207 ! mucosa of large intestine relationship: part_of UBERON:0001240 ! muscularis mucosae of intestine def: "A muscularis mucosa that is part of a large intestine." [OBOL:automatic] xref: UMLS:C0734776 [Term] id: UBERON:0001240 name: muscularis mucosae of intestine comment: This class was created automatically from a combination of ontologies synonym: "intestine muscularis mucosa" EXACT [] xref: FMA:15691 ! Muscularis mucosae of intestine xref: MA:0002694 ! intestine muscularis mucosa intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001242 ! intestinal mucosa def: "A muscularis mucosa that is part of a intestine." [OBOL:automatic] [Term] id: UBERON:0001241 name: crypt of Lieberkuhn of small intestine def: "A crypt of lieberkuhn that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "small intestinal crypt of Lieberkuhn" EXACT [] synonym: "small intestine crypt of Lieberkuhn" EXACT [] synonym: "crypt of lieberkuhn of small bowel" EXACT [OBOL:automatic] synonym: "crypt of lieberkuhn of small intestine" EXACT [OBOL:automatic] synonym: "intestinal gland of small bowel" EXACT [OBOL:automatic] synonym: "intestinal gland of small intestine" EXACT [OBOL:automatic] synonym: "lieberkuhn crypt of small bowel" EXACT [OBOL:automatic] synonym: "lieberkuhn crypt of small intestine" EXACT [OBOL:automatic] synonym: "small bowel crypt of lieberkuhn" EXACT [OBOL:automatic] synonym: "small bowel intestinal gland" EXACT [OBOL:automatic] synonym: "small bowel lieberkuhn crypt" EXACT [OBOL:automatic] synonym: "small intestine crypt of lieberkuhn" EXACT [OBOL:automatic] synonym: "small intestine intestinal gland" EXACT [OBOL:automatic] synonym: "small intestine lieberkuhn crypt" EXACT [OBOL:automatic] xref: FMA:15693 ! Crypt of Lieberkuhn of small intestine xref: MA:0001552 ! small intestine crypt of lieberkuhn xref: SCTID:52688008 ! Small intestinal crypt of LieberkCIsogai et al.2001." [ZFIN:curator] comment: Editor notes: review this term, check taxon scope synonym: "MsA" RELATED [] xref: FMA:50570 ! Mesencephalic artery xref: TAO:0001068 ! mesencephalic artery xref: ZFA:0001068 ! mesencephalic artery is_a: UBERON:0001637 ! artery relationship: supplies UBERON:0001891 ! midbrain xref: XAO:0004173 ! mesencephalic artery property_value: external_definition "Develops from the proximal portion of the primitive mesencephalic artery. Isogai et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001068", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from primitive mesencephalic artery (TAO:0001062)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001068", date_retrieved="2012-08-14"} [Term] id: UBERON:0010205 name: mesencephalic vein def: "One of the several veins that drain the mesencephalon; the posterior ones are tributaries to the great cerebral vein; the lateral ones are tributaries to the basal vein. The main veins are: pontomesencephalic vein [TA] (vena pontomesencephalica [TA]), interpeduncular veins [TA] (venae interpedunculares [TA]), intercollicular vein [TA] (vena intercollicularis [TA]), and lateral mesencephalic vein [TA] (vena mesencephalica lateralis [TA])[MedLex]. The major vein of the midbrain, which crosses the midbrain medially to meet it's partner the mesencephalic artery[XAO]." [XAO:0004174, http://www.medilexicon.com/medicaldictionary.php?t=97378] comment: Editor notes: review this term, check taxon scope; note FMA has specific subtypes synonym: "venae mesencephalicae" EXACT PLURAL [http://www.medilexicon.com/medicaldictionary.php?s=venae+mesencephalicae] synonym: "vena mesencephalica" EXACT [http://www.medilexicon.com/medicaldictionary.php?s=venae+mesencephalicae] is_a: UBERON:0001638 {source="XAO"} ! vein xref: XAO:0004174 ! mesencephalic vein xref: ZFA:0005092 ! mesencephalic vein xref: TAO:0005092 ! mesencephalic vein xref: SCTID:43225002 ! Entire mesencephalic vein synonym: "msv" RELATED [TAO:0005092] [Term] id: UBERON:0009688 name: posterior inferior cerebellar artery is_a: UBERON:0001637 {source="EHDAA2"} ! artery relationship: develops_from UBERON:0001535 {source="EHDAA2"} ! vertebral artery relationship: branch_of UBERON:0001535 {source="FMA"} ! vertebral artery relationship: part_of UBERON:0001535 {source="FMA"} ! vertebral artery xref: FMA:50518 ! posterior inferior cerebellar artery xref: EHDAA2:0000660 ! posterior inferior cerebellar artery synonym: "posterior inferior cerebellar artery" EXACT [EHDAA2:0000660] xref: ncithesaurus:Posterior_Inferior_Cerebellar_Artery ! Posterior Inferior Cerebellar Artery xref: SCTID:244212001 ! Entire posterior inferior cerebellar artery xref: UMLS:C0149573 [Term] id: UBERON:0009689 name: anterior inferior cerebellar artery is_a: UBERON:0001637 {source="EHDAA2"} ! artery relationship: develops_from UBERON:0001633 {source="EHDAA2"} ! basilar artery relationship: develops_from UBERON:0001532 {source="EHDAA2"} ! internal carotid artery relationship: branch_of UBERON:0001633 {source="FMA"} ! basilar artery relationship: part_of UBERON:0001633 {source="FMA"} ! basilar artery relationship: part_of UBERON:0003472 {source="EHDAA2"} ! cerebellar artery xref: FMA:50544 ! anterior inferior cerebellar artery xref: EHDAA2:0000587 ! anterior inferior cerebellar artery xref: ncithesaurus:Anterior_Inferior_Cerebellar_Artery ! Anterior Inferior Cerebellar Artery xref: SCTID:244213006 ! Entire anterior inferior cerebellar artery xref: UMLS:C0226245 [Term] id: UBERON:0001635 name: superior cerebellar artery def: "The superior cerebellar artery (SCA) arises near the termination of the basilar artery. It passes lateralward, immediately below the oculomotor nerve, which separates it from the posterior cerebral artery, winds around the cerebral peduncle, close to the trochlear nerve, and, arriving at the upper surface of the cerebellum, divides into branches which ramify in the pia mater and anastomose with those of the inferior cerebellar arteries. Several branches are given to the pineal body, the anterior medullary velum, and the tela chorioidea of the third ventricle. [WP,unvetted]." [Wikipedia:Superior_cerebellar_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:50573 ! Superior cerebellar artery xref: MA:0001934 ! superior cerebellar artery xref: ncithesaurus:Superior_Cerebellar_Artery ! Superior Cerebellar Artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e1/CerebellumArteries.jpg/200px-CerebellumArteries.jpg xref: EMAPA:19309 ! superior cerebellar artery is_a: UBERON:0001637 ! artery relationship: part_of UBERON:0001633 ! basilar artery relationship: supplies UBERON:0001895 ! metencephalon relationship: supplies UBERON:0002037 ! cerebellum xref: SCTID:244214000 ! Entire superior cerebellar artery xref: EHDAA2:0000681 ! superior cerebellar artery synonym: "arteria superior cerebelli" RELATED LATIN [Wikipedia:Superior_cerebellar_artery] xref: http://upload.wikimedia.org/wikipedia/commons/e/e1/CerebellumArteries.jpg xref: UMLS:C0149575 [Term] id: UBERON:0001636 name: posterior cerebral artery def: "The posterior cerebral artery (PCA) is one of a pair of blood vessels that supplies oxygenated blood to the posterior aspect of the brain in human anatomy]. It arises near the intersection of the posterior communicating artery and the basilar artery and connects with the ipsilateral middle cerebral artery (MCA) and internal carotid artery via the posterior communicating artery (PCommA). [WP,unvetted]." [Wikipedia:Posterior_cerebral_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:50583 ! Posterior cerebral artery xref: GAID:488 ! posterior cerebral artery xref: MA:0002022 ! posterior cerebral artery xref: ncithesaurus:Posterior_Cerebral_Artery ! Posterior Cerebral Artery xref: OpenCyc:Mx4rwO4qIJwpEbGdrcN5Y29ycA ! posterior cerebral artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/25/Gray517.png/200px-Gray517.png xref: EMAPA:17861 ! posterior cerebral artery xref: EMAPA:18616 ! posterior of cerebral artery xref: MESH:A07.231.114.228.700 ! posterior cerebral artery is_a: UBERON:0004449 ! cerebral artery relationship: part_of UBERON:0001633 ! basilar artery xref: SCTID:181313007 ! Entire posterior cerebral artery xref: EHDAA2:0000659 ! posterior cerebral artery synonym: "arteria cerebri posterior" RELATED LATIN [Wikipedia:Posterior_cerebral_artery] xref: http://upload.wikimedia.org/wikipedia/commons/2/25/Gray517.png relationship: in_lateral_side_of UBERON:0001633 {source="FMA-abduced-lr"} ! basilar artery xref: UMLS:C0149576 [Term] id: UBERON:0003509 ! arterial blood vessel name: arterial blood vessel def: "A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta." [UBERON:cjm] comment: only in MA - supertype of artery, arteriole, aorta. xref: MA:0000061 ! arterial blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004572 ! arterial system [Term] id: UBERON:0001637 name: artery def: "An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]." [AEO:JB] comment: Editor notes: Note that in FMA an artery is a tree, whereas AEO/JB defines it as a tube; FMA includes a separate class for what it calls the trunk. Classification in this ontology may currently (Jan 2012) represent a mix of both schemes, although we are gradually revising in the direction of the AEO scheme. subset: uberon_slim subset: vertebrate_core synonym: "arterial subtree" EXACT [] synonym: "arterial system" RELATED [] synonym: "arterial tree organ part" EXACT [] synonym: "arterial vessel" RELATED [] xref: BTO:0000573 xref: EFO:0000814 ! artery xref: FMA:50720 ! Artery xref: GAID:468 ! artery xref: galen:Artery xref: VHOG:0001251 ! artery xref: MA:0000064 ! artery xref: MAT:0000034 ! artery xref: MIAA:0000034 ! artery xref: ncithesaurus:Artery xref: TAO:0000005 ! artery xref: XAO:0000114 ! artery xref: ZFA:0000005 ! artery xref: OpenCyc:Mx4rvVjknZwpEbGdrcN5Y29ycA ! artery xref: EHDAA2:0000143 ! arterial system (also: UBERON:0004572 'arterial system') xref: AEO:0000208 ! artery xref: MESH:A07.231.114 ! artery xref: EV:0100026 ! artery xref: EHDAA2:0003253 ! artery is_a: UBERON:0001981 ! blood vessel relationship: part_of UBERON:0004572 ! arterial system relationship: channels_from UBERON:0000948 ! heart xref: AAO:0010211 ! artery xref: SCTID:362877004 ! Entire artery property_value: external_definition "Part of the circulatory system composed of blood vessels which carry oxygenated blood away from the heart to the rest of the body.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010211", date_retrieved="2012-06-20", source="AAO:BJB"} synonym: "arteries" EXACT PLURAL [TAO:0000005] property_value: homology_notes "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {external_class="VHOG:0001251", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH\, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "arterial" xsd:string xref: UMLS:C0003842 [Term] id: UBERON:0001638 name: vein def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [Wikipedia:Vein] comment: TODO - check with MA - vein vs venous blood vessel subset: uberon_slim subset: vertebrate_core synonym: "venous subtree" BROAD [] synonym: "venous tree organ part" EXACT [] synonym: "venous vessel" BROAD [] xref: BTO:0000234 xref: EFO:0000816 ! vein xref: FMA:50723 ! Vein xref: GAID:492 ! vein xref: VHOG:0001252 ! vein xref: MA:0000067 ! vein xref: MAT:0000037 ! vein xref: MIAA:0000037 ! vein xref: OpenCyc:Mx4rvVjkWpwpEbGdrcN5Y29ycA xref: TAO:0000082 ! vein xref: XAO:0000115 ! vein xref: ZFA:0000082 ! vein xref: ncithesaurus:Vein ! Vein xref: galen:Vein ! vein xref: OpenCyc:Mx4rvVjkWpwpEbGdrcN5Y29ycA ! vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c2/Venous_system_en.svg/200px-Venous_system_en.svg.png xref: AEO:0000209 ! vein xref: MESH:A07.231.908 ! vein xref: EV:0100031 ! vein xref: EHDAA2:0003254 ! vein is_a: UBERON:0003920 ! venous blood vessel relationship: channels_from UBERON:0001982 ! capillary xref: AAO:0010212 ! vein xref: SCTID:181367001 ! Entire vein xref: VHOG:0001743 ! vein synonym: "vena" RELATED LATIN [Wikipedia:Vein] xref: http://upload.wikimedia.org/wikipedia/commons/c/c2/Venous_system_en.svg property_value: external_definition "Part of the circulatory system composed of blood vessels which carry blood from other organs, tissues, and cells to the heart.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010212", date_retrieved="2012-06-20", source="AAO:BJB"} synonym: "venae" RELATED PLURAL [VHOG:0001743] property_value: homology_notes "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {external_class="VHOG:0001743", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH\, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0042449 [Term] id: UBERON:0005806 ! portal system name: portal system def: "In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]." [Wikipedia:Portal_venous_system] xref: FMA:45628 ! portal venous system synonym: "portal venous system" EXACT [FMA:45628] is_a: UBERON:0002049 ! vasculature relationship: part_of UBERON:0004535 ! cardiovascular system xref: ncithesaurus:Portal_Venous_System ! Portal Venous System xref: SCTID:362063001 ! Entire portal venous system xref: MESH:A07.231.908.670 ! portal system xref: UMLS:C0226727 [Term] id: UBERON:0010194 ! hepatic portal system name: hepatic portal system def: "A portal system that begins in capillaries in the wall of the digestive tract and and runs as the hepatic portal vein to the liver." [ISBN10:0073040584] is_a: UBERON:0005806 ! portal venous system xref: AAO:0010225 ! hepatic-portal system synonym: "hepatic-portal system" EXACT [AAO:0010225] synonym: "portal system of liver" EXACT [] property_value: external_definition "Part of the circulatory system which includes the ventral abdominal vein, pelvic veins, and portal vein and collects blood from the pelvic region, liver, gall bladder and stomach.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010225", date_retrieved="2012-06-20", source="AAO:BJB"} [Term] id: UBERON:0010195 name: renal portal system def: "A portal system that transports blood returning from capillary beds within tail or hindlimbs through paired renal portal veins that empty into capillaries within the kidneys." [ISBN10:0073040584] comment: Function notes: function not well understood. Taxon notes: present in all classes of vertebrates except mammals; the mammalian kidney has a low pressure vascular network that may be its counterpart [ISBN10:0073040584] synonym: "renal-portal system" EXACT [AAO:0010518] synonym: "portal system of kidney" EXACT [] is_a: UBERON:0005806 ! portal venous system relationship: never_in_taxon NCBITaxon:40674 {source="ISBN10:0073040584"} ! Mammalia xref: AAO:0010518 ! renal-portal system property_value: external_definition "Part of the circulatory system in which the veins of the hindlimb combine to form the pair Jacobson's veins which receive many small vesicles from the kidney and also collects blood from the oviducal vein.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010518", date_retrieved="2012-06-20", source="AAO:BJB"} [Term] id: UBERON:0002017 name: portal vein def: "A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]." [BTO:0001792] subset: uberon_slim synonym: "portal venous tree organ part" EXACT [FMA:66645] xref: EHDAA:6510 ! portal vein xref: FMA:66645 ! Portal vein xref: GAID:540 ! portal vein xref: VHOG:0000656 ! portal vein xref: MA:0002198 ! portal vein xref: OpenCyc:Mx4rv_bem5wpEbGdrcN5Y29ycA xref: XAO:0000392 ! portal vein xref: ncithesaurus:Portal_Vein ! Portal Vein xref: BTO:0001792 ! portal vein xref: galen:PortalVein ! portal vein xref: OpenCyc:Mx4rv_bem5wpEbGdrcN5Y29ycA ! portal vein xref: EHDAA2:0001485 ! portal vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Gray591.png/200px-Gray591.png xref: EMAPA:17349 ! portal vein xref: MESH:A07.231.908.670.567 ! portal vein is_a: UBERON:0001638 {source="FMA"} ! vein relationship: part_of UBERON:0005806 ! portal venous system xref: SCTID:362064007 ! Entire portal vein xref: UMLS:C0032718 [Term] id: UBERON:0001639 name: hepatic portal vein def: "A portal vein that transports nutrients from the digestive tract to the liver[Kardong]. A vein in the abdominal cavity that drains blood from the gastrointestinal tract and spleen. It is usually formed by the confluence of the superior mesenteric and splenic veins, and also receives blood from the inferior mesenteric, gastric, and cystic veins. The hepatic portal vein is a major component of the hepatic portal system, one of the main portal venous systems in the body. Conditions involving the hepatic portal vein cause considerable illness and death. An important example of such a condition is elevated blood pressure in the hepatic portal vein. This condition, called portal hypertension, is a major complication of cirrhosis worldwide. [WP,unvetted]." [Wikipedia:Hepatic_portal_vein, http://sourceforge.net/tracker/?func=detail&aid=3091300&group_id=76834&atid=1205376, ISBN10:0073040584] subset: uberon_slim subset: vertebrate_core synonym: "hepatic portal tree" EXACT [] synonym: "HPV" RELATED [] synonym: "primary hepatic portal veins" RELATED [] synonym: "portal vein" RELATED INCONSISTENT [] synonym: "liver portal vein" EXACT [OBOL:automatic] synonym: "portal vein of liver" EXACT [OBOL:automatic] synonym: "primary hepatic portal vein" RELATED [ZFA:0005090] xref: FMA:50735 ! Hepatic portal vein xref: VHOG:0000642 ! hepatic portal vein xref: MA:0002132 ! hepatic portal vein xref: TAO:0005090 ! hepatic portal vein xref: ZFA:0005090 ! hepatic portal vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Gray591.png/200px-Gray591.png is_a: UBERON:0002017 {source="MA"} ! portal vein relationship: overlaps UBERON:0002107 ! liver relationship: part_of UBERON:0010194 ! hepatic portal system relationship: develops_from UBERON:0005487 {source="Wikipedia:Vitelline_vein"} ! vitelline vein xref: AAO:0010214 ! hepatic portal vein synonym: "vena portae hepatis" RELATED LATIN [Wikipedia:Hepatic_portal_vein] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png property_value: homology_notes "Adults of all vertebrates lose the vitelline veins and establish a single large hepatic portal vein (...) by the selective retention of parts of the left and right subintestinals and of several anastomoses that occur between them within and just posterior to the liver.[well established][VHOG]" xsd:string {external_class="VHOG:0000642", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.265", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0010193 name: renal portal vein def: "A portal vein that empties into capillaries within the kidneys." [ISBN10:0073040584] comment: Function notes: function not well understood. [ISBN10:0073040584] synonym: "renal portal veins" EXACT PLURAL [ZFA:0000577] xref: TAO:0000577 ! renal portal vein is_a: UBERON:0001638 {source="ZFA"} ! vein relationship: part_of UBERON:0002201 {source="ZFA"} ! vasculature of trunk xref: ZFA:0000577 ! renal portal vein [Term] id: UBERON:0012254 ! abdominal aorta artery name: abdominal aorta artery def: "An artery that originates from the abdominal aorta" [UBERON:cjm, http://en.wikipedia.org/wiki/Abdominal_aorta#Branches] synonym: "artery of abdomen" EXACT [] synonym: "abdominal artery" EXACT [] intersection_of: UBERON:0001637 ! artery intersection_of: branch_of UBERON:0001516 ! abdominal aorta xref: SCTID:281470000 ! Entire artery of abdomen [Term] id: UBERON:0001640 name: celiac artery def: "The celiac artery, also known as the celiac trunk, is the first major branch of the abdominal aorta." [Wikipedia:Celiac_artery] comment: dorsal aorta in Kardong subset: uberon_slim synonym: "coeliac artery" EXACT [Wikipedia:Celiac_artery] synonym: "coeliac trunk" RELATED [Wikipedia:Celiac_artery] synonym: "celiac tree" EXACT [] synonym: "coeliac axis" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunck" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunk" RELATED [Wikipedia:Celiac_artery] synonym: "truncus coeliacus" RELATED [Wikipedia:Celiac_artery] synonym: "truncus cœliacus" RELATED LATIN [Wikipedia:Celiac_artery] synonym: "truncus coeliacus" RELATED LATIN [Wikipedia:Celiac_artery] synonym: "arteria cœliaca" RELATED LATIN [Wikipedia:Celiac_artery] synonym: "arteria coeliaca" RELATED LATIN [Wikipedia:Celiac_artery] xref: FMA:50737 ! Celiac artery xref: GAID:483 ! celiac artery xref: MA:0001931 ! celiac artery xref: ncithesaurus:Coeliac_Artery ! Coeliac Artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Gray532.png/200px-Gray532.png xref: MESH:A07.231.114.207 ! celiac artery is_a: UBERON:0004573 {source="FMA"} ! systemic artery relationship: branch_of UBERON:0001516 {source="Wikipedia", notes="dorsal aorta in primitive verts"} ! abdominal aorta relationship: develops_from UBERON:0006002 {source="Wikipedia"} ! vitelline artery relationship: supplies UBERON:0000160 {source="Kardong"} ! intestine relationship: supplies UBERON:0000945 {source="Kardong"} ! stomach relationship: supplies UBERON:0002106 {source="Kardong"} ! spleen relationship: supplies UBERON:0002107 {source="Kardong"} ! liver xref: SCTID:181340007 ! Entire celiac artery xref: EHDAA2:0004519 ! coeliac trunk (also: UBERON:0006637 'coeliac trunk') xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png xref: UMLS:C0007569 [Term] id: UBERON:0005616 name: mesenteric artery def: "Arteries which arise from the abdominal aorta and distribute to most of the intestines." [MESH:A07.231.114.565, Wikipedia:Mesenteric_artery] comment: Editors note: includes posterior and anterior mesenteric arteries, which branch from the dorsal aorta (see Kardong), and superior and inferior mesenteric arteries xref: MA:0002003 ! mesenteric artery xref: EHDAA2:0001123 ! mesenteric artery xref: BTO:0000779 ! mesenteric artery xref: EMAPA:17312 ! mesenteric artery xref: MESH:A07.231.114.565 ! mesenteric artery xref: VHOG:0001117 ! mesenteric artery xref: EHDAA:4343 ! mesenteric artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000160 ! intestine relationship: branch_of UBERON:0001516 {source="Wikipedia"} ! abdominal aorta xref: ncithesaurus:Mesenteric_Artery ! Mesenteric Artery xref: SCTID:281084003 ! Entire mesenteric artery xref: XAO:0000370 ! arteria mesenterica posterior xref: UMLS:C0025465 [Term] id: UBERON:0001641 name: transverse sinus def: "The transverse sinuses (left and right lateral sinuses), within a human head, are two areas beneath the brain, which allow blood veins to span the area, from the back of the head towards the nose. They drain from the straight sinus and superior sagittal sinus (along the top and back of the brain) to the sigmoid sinuses (at the center of the head), at the internal jugular vein. See diagram (at right): labeled under the brain as '' . The transverse sinuses are of large size and begin at the internal occipital protuberance; one, generally the right, being the direct continuation of the superior sagittal sinus, the other of the straight sinus. Each transverse sinus passes lateralward and forward, describing a slight curve with its convexity upward, to the base of the petrous portion of the temporal bone, and lies, in this part of its course, in the attached margin of the tentorium cerebelli; it then leaves the tentorium and curves downward and medialward to reach the jugular foramen, where it ends in the internal jugular vein. In its course it rests upon the squama of the occipital, the mastoid angle of the parietal, the mastoid part of the temporal, and, just before its termination, the jugular process of the occipital; the portion which occupies the groove on the mastoid part of the temporal is sometimes termed the sigmoid sinus. The transverse sinuses are frequently of unequal size, with the one formed by the superior sagittal sinus being the larger; they increase in size as they proceed, from back to center. On transverse section, the horizontal portion exhibits a prismatic form, the curved portion has a semicylindrical form. They receive the blood from the superior petrosal sinuses at the base of the petrous portion of the temporal bone; they communicate with the veins of the pericranium by means of the mastoid and condyloid emissary veins; and they receive some of the inferior cerebral and inferior cerebellar veins, and some veins from the diploë. The petrosquamous sinus, when present, runs backward along the junction of the squama and petrous portion of the temporal, and opens into the transverse sinus. [WP,unvetted]." [Wikipedia:Transverse_sinuses] comment: todo - check su subset: uberon_slim synonym: "groove for right and left transverse sinuses" RELATED [Wikipedia:Transverse_sinuses] synonym: "sinus transversus" RELATED [Wikipedia:Transverse_sinuses] synonym: "transverse sinus" RELATED [Wikipedia:Transverse_sinuses] synonym: "transverse sinus vein" RELATED [Wikipedia:Transverse_sinuses] synonym: "sinus transversus durae matris" EXACT LATIN [Wikipedia:Transverse_sinuses] xref: FMA:50763 ! Transverse sinus xref: MA:0001868 ! transverse sinus xref: OpenCyc:Mx4rwDb62ZwpEbGdrcN5Y29ycA ! transverse sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Gray488_blue.gif/200px-Gray488_blue.gif xref: EMAPA:18637 ! transverse is_a: UBERON:0006615 {source="MA"} ! venous sinus relationship: part_of UBERON:0000033 ! head xref: ncithesaurus:Transverse_Sinus ! Transverse Sinus xref: SCTID:279262004 ! Entire transverse sinus synonym: "lateral sinus" RELATED [FMA:50763] [Term] id: UBERON:0009968 ! primitive superior sagittal sinus name: primitive superior sagittal sinus is_a: UBERON:0001638 {source="EHDAA2"} ! vein relationship: part_of UBERON:0005486 {source="EHDAA2"} ! venous dural sinus xref: EHDAA2:0001527 ! primitive superior sagittal sinus xref: EMAPA:18636 ! superior sagittal xref: EHDAA:9876 ! primitive superior sagittal sinus [Term] id: UBERON:0001642 name: superior sagittal sinus def: "The superior sagittal sinus (also known as the superior longitudinal sinus), within a human cranium, is an area above/behind the brain, which allows blood veins to span the area, from the top of the head towards the back. It is believed that the cerebrospinal fluid drains through the arachnoid granulations into the dural venous sinuses of the superior sagittal sinus. [WP,unvetted]." [Wikipedia:Superior_sagittal_sinus] subset: uberon_slim xref: FMA:50767 ! Superior sagittal sinus xref: MA:0001867 ! superior sagittal sinus xref: OpenCyc:Mx4rv9naEJwpEbGdrcN5Y29ycA xref: ncithesaurus:Superior_Sagittal_Sinus ! Superior Sagittal Sinus xref: OpenCyc:Mx4rv9naEJwpEbGdrcN5Y29ycA ! superior sagittal sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Gray488_blue.gif/200px-Gray488_blue.gif is_a: UBERON:0006615 {source="MA"} ! venous sinus relationship: develops_from UBERON:0009968 {source="cjm"} ! primitive superior sagittal sinus xref: SCTID:362075006 ! Entire superior sagittal sinus synonym: "sinus sagittalis superior" RELATED LATIN [Wikipedia:Superior_sagittal_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray488_blue.gif xref: UMLS:C0226859 [Term] id: UBERON:0007152 name: inferior sagittal sinus xref: FMA:50768 ! Inferior sagittal sinus xref: EMAPA:18635 ! inferior sagittal is_a: UBERON:0006615 {source="cjm"} ! venous sinus relationship: part_of UBERON:0005486 ! venous dural sinus xref: ncithesaurus:Inferior_Sagittal_Sinus ! Inferior Sagittal Sinus xref: SCTID:279260007 ! Entire inferior sagittal sinus xref: UMLS:C0226861 [Term] id: UBERON:0001643 name: oculomotor nerve def: "Cranial nerve which connects the midbrain to the extra-ocular and intra-ocular muscles. // Cranial nerve that runs to the eye muscles." [ISBN:0471209627, Wikipedia:Oculomotor_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "CN-III" RELATED [] synonym: "cranial nerve III" RELATED [] synonym: "occulomotor" RELATED [] synonym: "oculomotor III nerve" EXACT [] synonym: "Oculomotor nerve [III]" EXACT [] synonym: "oculomotor nerve tree" EXACT [] synonym: "third cranial nerve" EXACT [] synonym: "oculomotor III" EXACT [EHDAA2:0001284] xref: FMA:50864 ! Oculomotor nerve xref: GAID:829 ! oculomotor nerve xref: VHOG:0000692 ! oculomotor nerve xref: MA:0001095 ! oculomotor III nerve xref: NIF_GrossAnatomy:birnlex_1646 ! Oculomotor nerve xref: TAO:0000405 ! cranial nerve III xref: XAO:0003090 ! cranial nerve III xref: ZFA:0000405 ! cranial nerve III xref: ncithesaurus:Oculomotor_Nerve ! Oculomotor Nerve xref: OpenCyc:Mx4rvj7pZpwpEbGdrcN5Y29ycA ! oculomotor nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/69/Gray776.png/200px-Gray776.png xref: EHDAA2:0001284 ! oculomotor III xref: EMAPA:17574 ! oculomotor III xref: MESH:A08.800.800.120.600 ! oculomotor nerve xref: EHDAA:3736 ! oculomotor III xref: BM:MB-IIIN ! oculomotor nerve is_a: UBERON:0001785 ! cranial nerve relationship: develops_from_part_of UBERON:0005073 {source="GO"} ! preganglionic parasympathetic nervous system relationship: develops_from UBERON:0010285 {source="Wikipedia"} ! midbrain basal plate synonym: "nervus oculomotorius [iii]" EXACT LATIN [FMA:TA, FMA:50864] xref: AAO:0010468 ! 03 oculomotor nerve xref: SCTID:362456009 ! Entire oculomotor nerve synonym: "nervus oculomotorius" RELATED LATIN [Wikipedia:Oculomotor_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/6/69/Gray776.png property_value: external_definition "Somatic efferent fibers which innervate four eye muscles.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010468", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000692", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0028864 [Term] id: UBERON:0001644 name: trochlear nerve def: "Cranial nerve that runs to the eye muscles." [ISBN:0471209627, Wikipedia:Trochlear_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "CN-IV" RELATED [] synonym: "cranial nerve IV" RELATED [] synonym: "fourth cranial nerve" EXACT [] synonym: "pathetic nerve" RELATED [] synonym: "superior oblique nerve" EXACT [] synonym: "trochlear" RELATED [] synonym: "trochlear IV nerve" EXACT [] synonym: "Trochlear nerve [IV]" EXACT [] synonym: "trochlear nerve tree" EXACT [] xref: FMA:50865 ! Trochlear nerve xref: GAID:838 ! trochlear nerve xref: VHOG:0000705 ! trochlear nerve xref: MA:0001105 ! trochlear IV nerve xref: NIF_GrossAnatomy:birnlex_1654 ! Trochlear nerve xref: TAO:0000600 ! cranial nerve IV xref: XAO:0003091 ! cranial nerve IV xref: ZFA:0000600 ! cranial nerve IV xref: EMAPA:18218 ! trochlear IV xref: EHDAA2:0002090 ! trochlear IV xref: ncithesaurus:Trochlear_Nerve ! Trochlear Nerve xref: OpenCyc:Mx4rvyeBQ5wpEbGdrcN5Y29ycA ! fourth cranial nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Trochlear_nerve.png/200px-Trochlear_nerve.png xref: MESH:A08.800.800.120.800 ! trochlear nerve xref: BM:IVN ! trochlear nerve is_a: UBERON:0001785 ! cranial nerve synonym: "nervus trochlearis [iv]" EXACT LATIN [FMA:TA, FMA:50865] xref: AAO:0010469 ! 04 trochlear nerve xref: SCTID:180939009 ! Entire trochlear nerve synonym: "nervus trochlearis" RELATED LATIN [Wikipedia:Trochlear_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Trochlear_nerve.png property_value: external_definition "Somatic efferent nerve which supplies a single eye muscle, the m. obliquus superior.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010469", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000705", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0041159 [Term] id: UBERON:0001645 name: trigeminal nerve def: "Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw)." [ISBN:0471209627, Wikipedia:Trigeminal_nerve] comment: Taxon notes: the ophthalmic usually usually merges with the other two. In some vertebrates, the ophthalmic emerges from the brain separately[Kardong] The trigeminal nerve has 3 branches in mammals - similar branches are present in nonmammalian vertebrates, but in some a separate profundus nerve that corresponds to opthalmic branch in mammls[ISBN10:0471888893] subset: uberon_slim subset: vertebrate_core synonym: "CN-V" RELATED [] synonym: "cranial nerve V" RELATED [] synonym: "fifth cranial nerve" EXACT [] synonym: "trigeminal nerve [V]" EXACT [] synonym: "trigeminal nerve tree" EXACT [] synonym: "trigeminal v nerve" EXACT [] synonym: "trigeminal V" EXACT [EHDAA2:0002084] synonym: "nervus trigeminus" RELATED [BTO:0001072] synonym: "trigeminus" RELATED [BTO:0001072] xref: BTO:0001072 xref: FMA:50866 ! Trigeminal nerve xref: GAID:726 ! trigeminal nerve xref: VHOG:0000704 ! trigeminal nerve xref: MA:0001100 ! trigeminal V nerve xref: NIF_GrossAnatomy:birnlex_869 ! Trigeminal nerve xref: TAO:0000697 ! cranial nerve V xref: XAO:0003092 ! cranial nerve V xref: ZFA:0000697 ! cranial nerve V xref: ncithesaurus:Trigeminal_Nerve ! Trigeminal Nerve xref: EFO:0001402 ! trigeminal nerve xref: OpenCyc:Mx4rwMF8CJwpEbGdrcN5Y29ycA ! trigeminal nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/99/Gray778_Trigeminal.png/200px-Gray778_Trigeminal.png xref: EHDAA2:0002084 ! trigeminal V xref: EMAPA:17576 ! trigeminal V of cranial of nerve of central nervous system of nervous system of organ system xref: MESH:A08.800.800.120.760 ! trigeminal nerve xref: EHDAA:3738 ! trigeminal V xref: BM:VN ! trigeminal nerve is_a: UBERON:0001785 ! cranial nerve relationship: has_developmental_contribution_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon relationship: has_developmental_contribution_from UBERON:0002342 {source="Wikipedia"} ! neural crest synonym: "nervus trigeminus [v]" EXACT LATIN [FMA:TA, FMA:50866] xref: AAO:0010470 ! 05 trigeminal nerve xref: SCTID:362459002 ! Entire trigeminal nerve synonym: "nervus trigeminus" EXACT LATIN [Wikipedia:Trigeminal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/9/99/Gray778_Trigeminal.png property_value: external_definition "Nerve consists of motor and sensory components. Ganglion cells of the sensory component form the proximal part of the trigeminal (Gasserian) ganglion. From the ganglion 3 major rami innervate jaws, snout, and buccal roof.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010470", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000704", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0040996 [Term] id: UBERON:0001646 name: abducens nerve def: "Cranial nerve that runs to the eye muscles." [ISBN:0471209627, Wikipedia:Abducens_nerve] comment: Taxon notes: Homologous abducens nerves are found in all vertebrates except lampreys and hagfishes.[WP] It controls the movement of a single muscle, the lateral rectus muscle of the eye, in humans. In most other mammals it also innervates the musculus retractor bulbi, which can retract the eye for protection[WP] subset: uberon_slim subset: vertebrate_core synonym: "abducens nerve [VI]" EXACT [] synonym: "abducens nerve tree" EXACT [] synonym: "abducens VI nerve" EXACT [] synonym: "abducent nerve" RELATED [] synonym: "abducent nerve [VI]" EXACT [] synonym: "CN-VI" RELATED [] synonym: "cranial nerve VI" RELATED [] synonym: "lateral rectus nerve" EXACT [] synonym: "nervus abducens" EXACT [] synonym: "sixth cranial nerve" EXACT [] xref: FMA:50867 ! Abducens nerve xref: GAID:824 ! abducens nerve xref: VHOG:0000697 ! abducens nerve xref: MA:0001087 ! abducens VI nerve xref: NIF_GrossAnatomy:birnlex_876 ! Abducens nerve xref: TAO:0000310 ! cranial nerve VI xref: XAO:0003093 ! cranial nerve VI xref: ZFA:0000310 ! cranial nerve VI xref: ncithesaurus:Abducens_Nerve ! Abducens Nerve xref: OpenCyc:Mx4rvjl41ZwpEbGdrcN5Y29ycA ! abducens nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Abducens_nerve1.png/200px-Abducens_nerve1.png xref: EHDAA2:0000103 ! abducens VI nerve xref: MESH:A08.800.800.120.030 ! abducens nerve xref: BM:Pons-VIN ! abducens nerve is_a: UBERON:0001785 ! cranial nerve relationship: only_in_taxon NCBITaxon:7776 {source="Wikipedia", notes="found in all vertebrates except lampreys and hagfishes"} ! Gnathostomata relationship: develops_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon synonym: "nervus abducens [VI]" EXACT LATIN [FMA:TA, FMA:50867] xref: AAO:0010471 ! 06 abducens nerve xref: SCTID:180941005 ! Entire abducens nerve synonym: "nervus abducens" RELATED LATIN [Wikipedia:Abducens_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/2/29/Abducens_nerve1.png property_value: external_definition "Somatic motor nerve which bifurcates innervating m. rectus lateralis and m. retractor bulbi (eye muscles).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010471", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000697", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0000741 [Term] id: UBERON:0010271 name: musculus retractor bulbi def: "Cranial nerve VI innervated; ventral and posterior to the eye." [AAO:0010122] comment: Editors note: TODO - add innervation relationships // In most other mammals it also innervates the musculus retractor bulbi, which can retract the eye for protection[wiki/Abducens_nerve] synonym: "M. retractor bulbi" EXACT [] synonym: "retractor bulbi" EXACT [] synonym: "retractor bulbi muscle" EXACT [] is_a: UBERON:0001601 {source="cjm"} ! extra-ocular muscle relationship: never_in_taxon NCBITaxon:9606 {source="Wikipedia"} ! Homo sapiens xref: AAO:0010122 ! musculus retractor bulbi [Term] id: UBERON:0001647 name: facial nerve def: "Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches)." [ISBN:0471209627, Wikipedia:Facial_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "branchiomeric cranial nerve" EXACT [] synonym: "CN-VII" RELATED [] synonym: "cranial nerve VII" RELATED [] synonym: "Facial nerve [VII]" EXACT [] synonym: "facial nerve tree" EXACT [] synonym: "facial VII nerve" EXACT [] synonym: "seventh cranial nerve" EXACT [] synonym: "face nerve" EXACT [OBOL:automatic] synonym: "nerve of face" EXACT [OBOL:automatic] synonym: "facial VII" EXACT [EHDAA2:0000489] synonym: "nervus facialis" EXACT [ZFA:0000664] xref: FMA:50868 ! Facial nerve xref: GAID:719 ! facial nerve xref: VHOG:0000706 ! facial nerve xref: MA:0001091 ! facial VII nerve xref: NIF_GrossAnatomy:birnlex_827 ! Facial nerve xref: TAO:0000664 ! cranial nerve VII xref: XAO:0003094 ! cranial nerve VII xref: ZFA:0000664 ! cranial nerve VII xref: ncithesaurus:Facial_Nerve ! Facial Nerve xref: OpenCyc:Mx4rvthgEpwpEbGdrcN5Y29ycA ! facial nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Cranial_nerve_VII.svg/200px-Cranial_nerve_VII.svg.png xref: EHDAA2:0000489 ! facial VII xref: EMAPA:17796 ! facial VII of cranial of nerve of central nervous system of nervous system of organ system xref: MESH:A08.800.800.120.250 ! facial nerve xref: EHDAA:3729 ! facial VII xref: BM:Pons-VIIN ! facial nerve is_a: UBERON:0001785 ! cranial nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001456 ! face relationship: part_of UBERON:0001033 ! gustatory system relationship: develops_from_part_of UBERON:0005073 {source="GO"} ! preganglionic parasympathetic nervous system relationship: has_developmental_contribution_from UBERON:0003066 {source="Wikipedia"} ! pharyngeal arch 2 relationship: has_developmental_contribution_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon relationship: has_developmental_contribution_from UBERON:0002342 {source="Wikipedia"} ! neural crest synonym: "nervus facialis [vii]" EXACT LATIN [FMA:TA, FMA:50868] xref: AAO:0010472 ! 07 facial nerve xref: SCTID:362460007 ! Entire facial nerve synonym: "nervus facialis" RELATED LATIN [Wikipedia:Facial_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/1/1f/Cranial_nerve_VII.svg property_value: external_definition "Slender nerve composed of branchiomotor and visceral efferent fibers innervating the mouth and various muscles within the jaw. Sensory components innervate the bucccal roof and somatomotor components innervate the depressor musculature and muscle interhyoideus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010472", date_retrieved="2012-06-20", source="AAO:DSM"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000706", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0015462 [Term] id: UBERON:0009675 name: facial VII nerve chorda tympani branch is_a: UBERON:0001785 ! cranial nerve relationship: part_of UBERON:0001647 {source="EHDAA2"} ! facial nerve xref: EHDAA2:0000490 ! facial VII nerve chorda tympani branch xref: MA:0001092 ! facial VII nerve chorda tympani branch xref: VHOG:0001343 ! facial VII nerve chorda tympani branch xref: EMAPA:18217 ! chorda tympani branch xref: EHDAA:3719 ! chorda tympani branch [Term] id: UBERON:0001648 name: vestibulocochlear nerve def: "Cranial nerve that runs to the ear." [ISBN:0471209627, Wikipedia:Vestibulocochlear_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "acoustic nerve" EXACT [] synonym: "acoustic VIII nerve" EXACT [] synonym: "VIII nerve" EXACT [] synonym: "acoustic nerve (crosby)" EXACT [] synonym: "CN-VIII" EXACT [] synonym: "cochlear-vestibular nerve" EXACT [] synonym: "cochleovestibular nerve" EXACT [] synonym: "cranial nerve VIII" EXACT [] synonym: "eighth cranial nerve" EXACT [] synonym: "VIIIth cranial nerve" EXACT [] synonym: "octaval nerve" RELATED [] synonym: "stato-acoustic nerve" EXACT [] synonym: "statoacoustic nerve" RELATED [] synonym: "Vestibulocochlear nerve [VIII]" EXACT [] synonym: "vestibulocochlear nerve tree" EXACT [] synonym: "vestibulocochlear VIII nerve" EXACT [] synonym: "nervus vestibulocochlearis" RELATED [BTO:0003490] xref: FMA:50869 ! Vestibulocochlear nerve xref: GAID:839 ! vestibulocochlear nerve xref: VHOG:0000695 ! vestibulocochlear nerve xref: MA:0001109 ! vestibulocochlear VIII nerve xref: NIF_GrossAnatomy:birnlex_890 ! Vestibulocochlear nerve xref: OpenCyc:Mx4rvVjMFZwpEbGdrcN5Y29ycA xref: TAO:0000247 ! cranial nerve VIII xref: XAO:0003095 ! cranial nerve VIII xref: ZFA:0000247 ! cranial nerve VIII xref: EHDAA2:0002194 ! vestibulocochlear VIII xref: BTO:0003490 ! vestibulocochlear nerve (also: UBERON:0004727 'cochlear nerve') xref: OpenCyc:Mx4rvVjMFZwpEbGdrcN5Y29ycA ! acoustic nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Gray789.png/200px-Gray789.png xref: EMAPA:17801 ! vestibulocochlear VIII of cranial of nerve of central nervous system of nervous system of organ system xref: MESH:A08.800.800.120.910 ! vestibulocochlear nerve is_a: UBERON:0001785 ! cranial nerve relationship: continuous_with UBERON:0001844 ! cochlea relationship: develops_from UBERON:0003069 {source="Wikipedia"} ! otic placode synonym: "nervus vestibulocochlearis [viii]" EXACT LATIN [FMA:TA, FMA:50869] xref: ncithesaurus:Vestibulocochlear_Nerve ! Vestibulocochlear Nerve xref: AAO:0010473 ! 08 auditory nerve xref: SCTID:180945001 ! Entire vestibulocochlear nerve xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray789.png property_value: external_definition "Nerve primarily composed of special somatic afferent fibers innervating the inner ear, and is involved in balance, position, and hearing.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010473", date_retrieved="2012-06-20", source="AAO:DSM"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000695", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0001162 [Term] id: UBERON:0004727 name: cochlear nerve def: "a nerve in the head that carries signals from the cochlea of the inner ear to the brain. It is part of the vestibulocochlear nerve, the 8th cranial nerve which is found in higher vertebrates; the other portion of the 8th cranial nerve is the vestibular nerve which carries spatial orientation information from the semicircular canals. The cochlear nerve is a sensory nerve, one which conducts to the brain information about the environment, in this case acoustic energy impinging on the tympanic membrane. The cochlear nerve arises from within the cochlea and extends to the brainstem, where its fibers make contact with the cochlear nucleus, the next stage of neural processing in the auditory system[WP]." [ISBN:Wikipedia:Cochlear_nerve] subset: uberon_slim synonym: "auditory nerve" EXACT [FMA:53431] synonym: "cochlear root of acoustic nerve" EXACT [FMA:53431] synonym: "cochlear root of eighth cranial nerve" EXACT [FMA:53431] synonym: "vestibulocochlear VIII nerve cochlear component" EXACT [MA:0001110] synonym: "nervus vestibulocochlearis" RELATED [BTO:0003490] synonym: "cochlear component" BROAD [] xref: FMA:53431 ! Cochlear nerve xref: GAID:723 ! cochlear nerve xref: MA:0001110 ! vestibulocochlear VIII nerve cochlear component xref: VHOG:0001182 ! vestibulocochlear VIII nerve cochlear component xref: ncithesaurus:Cochlear_Nerve ! Cochlear Nerve xref: BTO:0003490 ! vestibulocochlear nerve (also: UBERON:0001648 'vestibulocochlear nerve') xref: OpenCyc:Mx4rwIhQfZwpEbGdrcN5Y29ycA ! cochlear nerve xref: EHDAA2:0002195 ! vestibulocochlear VIII cochlear component xref: MESH:A08.800.800.120.910.120 ! cochlear nerve xref: BM:VIIIN ! auditory nerve is_a: UBERON:0001785 ! cranial nerve relationship: branch_of UBERON:0001648 ! vestibulocochlear nerve xref: SCTID:280286001 ! Entire cochlear nerve xref: UMLS:C0009201 [Term] id: UBERON:0003723 name: vestibular nerve def: "The vestibular nerve is one of the two branches of the Vestibulocochlear nerve (the cochlear nerve being the other). It goes to the semicircular canals via the vestibular ganglion. It receives positional information. Axons of the vestibular nerve synapse in the vestibular nucleus on the lateral floor and wall of the fourth ventricle in the pons and medulla. It arises from bipolar cells in the vestibular ganglion, ganglion of Scarpa, which is situated in the upper part of the outer end of the internal auditory meatus. [WP,unvetted]." [Wikipedia:Vestibular_nerve] synonym: "scarpa ganglion" RELATED [GAID:840] synonym: "scarpa's ganglion" RELATED [GAID:840] synonym: "scarpas ganglion" RELATED [GAID:840] synonym: "vestibular root of acoustic nerve" EXACT [FMA:53401] synonym: "vestibular root of eighth cranial nerve" EXACT [FMA:53401] synonym: "vestibulocochlear VIII nerve vestibular component" EXACT [MA:0001111] xref: FMA:53401 ! Vestibular nerve xref: GAID:840 ! vestibular nerve xref: MA:0001111 ! vestibulocochlear VIII nerve vestibular component xref: VHOG:0001181 ! vestibulocochlear VIII nerve vestibular component xref: ncithesaurus:Vestibular_Nerve ! Vestibular Nerve xref: OpenCyc:Mx4rvxAWX5wpEbGdrcN5Y29ycA ! vestibular nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Vestibular_system%27s_semicircular_canal-_a_cross-section.jpg/200px-Vestibular_system%27s_semicircular_canal-_a_cross-section.jpg xref: EHDAA2:0002200 ! vestibulocochlear VIII nerve vestibular component xref: MESH:A08.800.800.120.910.900 ! vestibular nerve xref: EMAPA:17803 ! vestibular component xref: EHDAA:3749 ! vestibular component is_a: UBERON:0001785 ! cranial nerve relationship: branch_of UBERON:0001648 ! vestibulocochlear nerve xref: SCTID:362464003 ! Entire vestibular nerve synonym: "nervus vestibularis" RELATED LATIN [Wikipedia:Vestibular_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Vestibular_system%27s_semicircular_canal-_a_cross-section.jpg xref: UMLS:C0042598 [Term] id: UBERON:0001649 name: glossopharyngeal nerve def: "Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult)." [ISBN:0471209627, Wikipedia:Glossopharyngeal_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "CN-IX" RELATED [] synonym: "cranial nerve IX" RELATED [] synonym: "glossopharyngeal IX nerve" EXACT [] synonym: "Glossopharyngeal nerve [IX]" EXACT [] synonym: "glossopharyngeal nerve tree" EXACT [] synonym: "ninth cranial nerve" EXACT [] synonym: "glossopharyngeal IX" EXACT [EHDAA2:0000709] synonym: "nervus glossopharyngeus" EXACT [ZFA:0000668] xref: FMA:50870 ! Glossopharyngeal nerve xref: GAID:827 ! glossopharyngeal nerve xref: VHOG:0000701 ! glossopharyngeal nerve xref: MA:0001093 ! glossopharyngeal IX nerve xref: NIF_GrossAnatomy:birnlex_899 ! Glossopharyngeal nerve xref: TAO:0000668 ! cranial nerve IX xref: XAO:0003096 ! cranial nerve IX xref: ZFA:0000668 ! cranial nerve IX xref: ncithesaurus:Glossopharyngeal_Nerve ! Glossopharyngeal Nerve xref: OpenCyc:Mx4rwIr5X5wpEbGdrcN5Y29ycA ! glossopharyngeal nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5e/Gray791.png/200px-Gray791.png xref: EHDAA2:0000709 ! glossopharyngeal IX xref: EMAPA:17268 ! glossopharyngeal IX of cranial of nerve of central nervous system of nervous system of organ system xref: MESH:A08.800.800.120.290 ! glossopharyngeal nerve xref: EHDAA:3733 ! glossopharyngeal IX xref: BTO:0004979 ! glossopharyngeal nerve is_a: UBERON:0001785 {source="FMA"} ! cranial nerve relationship: part_of UBERON:0001033 ! gustatory system relationship: has_developmental_contribution_from UBERON:0005239 {source="Wikipedia", notes="motor"} ! basal plate metencephalon relationship: has_developmental_contribution_from UBERON:0002342 {source="Wikipedia", notes="sensory"} ! neural crest synonym: "nervus glossopharyngeus [ix]" EXACT LATIN [FMA:TA, FMA:50870] xref: AAO:0010474 ! 09 glossopharyngeus nerve xref: SCTID:362465002 ! Entire glossopharyngeal nerve synonym: "nervus glossopharyngeus" RELATED LATIN [Wikipedia:Glossopharyngeal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png property_value: external_definition "Small nerve consisting of branchiomotor and visceral efferent and afferent fibers which innervate the m. subarculais rectus I, dorsal buccal mucosa, and the tongue.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010474", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000701", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0017679 [Term] id: UBERON:0001650 name: hypoglossal nerve def: "Nerve that innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO:0021566, Wikipedia:Hypoglossal_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "Hypoglossal nerve [XII]" EXACT [] synonym: "hypoglossal nerve tree" EXACT [] synonym: "hypoglossal XII nerve" EXACT [] synonym: "twelfth cranial nerve" EXACT [] synonym: "hypoglossal XII" EXACT [EHDAA2:0000798] synonym: "cranial nerve XII" EXACT [NIF_GrossAnatomy:birnlex_820] xref: FMA:50871 ! Hypoglossal nerve xref: GAID:828 ! hypoglossal nerve xref: VHOG:0000693 ! hypoglossal nerve xref: MA:0001094 ! hypoglossal XII nerve xref: NIF_GrossAnatomy:birnlex_820 ! Hypoglossal nerve xref: OpenCyc:Mx4rv9eWA5wpEbGdrcN5Y29ycA xref: ncithesaurus:Hypoglossal_Nerve ! Hypoglossal Nerve xref: BTO:0003386 ! hypoglossal nerve xref: OpenCyc:Mx4rv9eWA5wpEbGdrcN5Y29ycA ! hypoglossal nerve xref: EHDAA2:0000798 ! hypoglossal XII xref: EMAPA:17269 ! hypoglossal XII xref: MESH:A08.800.800.120.330 ! hypoglossal nerve xref: EHDAA:2859 ! hypoglossal XII is_a: UBERON:0001785 ! cranial nerve synonym: "nervus hypoglossus [xii]" EXACT LATIN [FMA:TA, FMA:50871] xref: AAO:0010477 ! 12 hypoglossus nerve xref: SCTID:362471008 ! Entire hypoglossal nerve xref: XAO:0004215 ! cranial nerve XII synonym: "nervus hypoglossus" RELATED LATIN [Wikipedia:Hypoglossal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/e/ef/Gray794.png property_value: external_definition "Nerve which innervates the muscles associated with the tongue including mm geniohyoideus, genioglossus, hyoglossus and rectus cervicis.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010477", date_retrieved="2012-06-20", source="AAO:EJS"} synonym: "CN-XII" RELATED [VHOG:0000693] property_value: external_definition "Cranial nerve that innervates muscles in the tongue. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-14, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000693", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Cranial nerves XI and XII evolved in the common ancestor to amniotes (non-amphibian tetrapods) thus totalling twelve pairs.[well established][VHOG]" xsd:string {external_class="VHOG:0000693", ontology="VHOG", source="http://en.wikipedia.org/wiki/Cranial_nerves", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0020614 [Term] id: UBERON:0001651 name: right pulmonary artery def: "The pulmonary arteries carry blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood. In the human heart, the pulmonary trunk (pulmonary artery or main pulmonary artery) begins at the base of the right ventricle. It is short and wide - approximately 5 cm (2 inches) in length and 3 cm (1.2 inches) in diameter. It then branches into two pulmonary arteries (left and right), which deliver deoxygenated blood to the corresponding lung. [WP,unvetted]." [Wikipedia:Right_pulmonary_artery] comment: TODO - add class 'pulmonary artery tree organ' subset: uberon_slim synonym: "right main pulmonary artery" EXACT [] synonym: "right pulmonary arterial tree" EXACT [] xref: FMA:50872 ! Right pulmonary artery xref: MA:0002500 ! right pulmonary artery xref: ncithesaurus:Right_Pulmonary_Artery ! Right Pulmonary Artery xref: galen:RightPulmonaryArtery ! right pulmonary artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Alveoli_diagram.png/200px-Alveoli_diagram.png is_a: UBERON:0002012 ! pulmonary artery xref: SCTID:244235003 ! Entire right pulmonary artery synonym: "arteria pulmonalis dextra" RELATED LATIN [Wikipedia:Right_pulmonary_artery] xref: http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png xref: UMLS:C0923924 [Term] id: UBERON:0001652 name: left pulmonary artery def: "The pulmonary arteries carry blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood. In the human heart, the pulmonary trunk (pulmonary artery or main pulmonary artery) begins at the base of the right ventricle. It is short and wide - approximately 5 cm (2 inches) in length and 3 cm (1.2 inches) in diameter. It then branches into two pulmonary arteries (left and right), which deliver deoxygenated blood to the corresponding lung. [WP,unvetted]." [Wikipedia:Left_pulmonary_artery] comment: TODO - add class 'pulmonary artery tree organ' subset: uberon_slim synonym: "left main pulmonary artery" EXACT [] synonym: "left pulmonary arterial tree" EXACT [] xref: FMA:50873 ! Left pulmonary artery xref: galen:LeftPulmonaryArtery xref: MA:0002032 ! left pulmonary artery xref: ncithesaurus:Left_Pulmonary_Artery ! Left Pulmonary Artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Alveoli_diagram.png/200px-Alveoli_diagram.png is_a: UBERON:0002012 ! pulmonary artery xref: SCTID:244234004 ! Entire left pulmonary artery synonym: "arteria pulmonalis sinistra" RELATED LATIN [Wikipedia:Left_pulmonary_artery] xref: http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png xref: UMLS:C0923925 [Term] id: UBERON:0001653 name: facial vein def: "The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]." [Wikipedia:Facial_vein] comment: Comment note MA and NCITA also has 'anterior facial vein' subset: uberon_slim synonym: "face vein" EXACT [OBOL:automatic] synonym: "vein of face" EXACT [OBOL:automatic] synonym: "vena facialis anterior" RELATED LATIN [Wikipedia:Facial_vein] synonym: "anterior facial vein" RELATED INCONSISTENT [Wikipedia:Facial_vein] xref: FMA:50874 ! Facial vein xref: MA:0002115 ! facial vein xref: ncithesaurus:Facial_Vein ! Facial Vein xref: OpenCyc:Mx4rvziz3JwpEbGdrcN5Y29ycA ! facial vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png xref: EMAPA:19220 ! facial vein is_a: UBERON:0001638 ! vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0001456 ! face relationship: tributary_of UBERON:0001586 {source="FMA"} ! internal jugular vein xref: AAO:0010513 ! facial vein xref: SCTID:181374006 ! Entire facial vein xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png property_value: external_definition "Vein which collects blood from muscles of the head and drains into the external jugular vein.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010513", date_retrieved="2012-06-20", source="AAO:BJB"} xref: UMLS:C0226532 [Term] id: UBERON:0001654 name: supra-orbital vein def: "The supraorbital vein begins on the forehead where it communicates with the frontal branch of the superficial temporal vein. It runs downward superficial to the Frontalis muscle, and joins the frontal vein at the medial angle of the orbit to form the angular vein. Previous to its junction with the frontal vein, it sends through the supraorbital notch into the orbit a branch which communicates with the ophthalmic vein; as this vessel passes through the notch, it receives the frontal diploic vein through a foramen at the bottom of the notch. The areas drained by this vessel are the forehead, eyebrow and upper eyelid. [WP,unvetted]." [Wikipedia:Supra-orbital_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "supraorbital vein" EXACT [] xref: FMA:50904 ! Supra-orbital vein xref: MA:0002228 ! supraorbital vein xref: ncithesaurus:Supra-orbital_Vein ! Supraorbital Vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001653 {source="FMA"} ! facial vein xref: SCTID:152006005 ! Entire supraorbital vein xref: UMLS:C0226535 [Term] id: UBERON:0001655 name: submental vein comment: This class was created automatically from a combination of ontologies xref: FMA:50925 ! Submental vein xref: MA:0002223 ! submental vein xref: ncithesaurus:Submental_Vein ! Submental Vein is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001653 {source="FMA/obol"} ! facial vein xref: SCTID:152309009 ! Entire submental vein xref: UMLS:C0226541 [Term] id: UBERON:0001656 name: retromandibular vein def: "The retromandibular vein (temporomaxillary vein, posterior facial vein), formed by the union of the superficial temporal and maxillary veins, descends in the substance of the parotid gland, superficial to the external carotid artery but beneath the facial nerve, between the ramus of the mandible and the sternocleidomastoideus muscle. It divides into two branches: an anterior, which passes forward and unites with the anterior facial vein to form the common facial vein. a posterior, which is joined by the posterior auricular vein and becomes the external jugular vein. [WP,unvetted]." [Wikipedia:Retromandibular_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "posterior facial vein" EXACT [] synonym: "vena retromandibularis" RELATED LATIN [Wikipedia:Retromandibular_vein] synonym: "vena facialis posterior" RELATED LATIN [Wikipedia:Retromandibular_vein] xref: FMA:50928 ! Retromandibular vein xref: MA:0002117 ! posterior facial vein xref: OpenCyc:Mx4rv0bn95wpEbGdrcN5Y29ycA xref: ncithesaurus:Temporo-maxillary_Vein ! Retromandibular Vein xref: OpenCyc:Mx4rv0bn95wpEbGdrcN5Y29ycA ! posterior facial vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png is_a: UBERON:0001653 ! facial vein relationship: tributary_of UBERON:0001101 {source="FMA"} ! external jugular vein xref: SCTID:151299003 ! Entire retromandibular vein xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png xref: UMLS:C0226520 [Term] id: UBERON:0001657 name: superficial temporal vein def: "The superficial temporal vein is a vein of the side of the head. [WP,unvetted]." [Wikipedia:Superficial_temporal_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:50932 ! Superficial temporal vein xref: MA:0002242 ! superficial temporal vein xref: ncithesaurus:Superficial_Temporal_Vein ! Superficial Temporal Vein xref: BTO:0003748 ! superficial temporal vein xref: OpenCyc:Mx4rvmANWZwpEbGdrcN5Y29ycA ! superficial temporal vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png xref: EMAPA:19315 ! superficial temporal vein is_a: UBERON:0001671 ! temporal vein relationship: tributary_of UBERON:0001101 {source="FMA/obol"} ! external jugular vein relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein relationship: tributary_of UBERON:0001656 {source="FMA/obol"} ! retromandibular vein xref: SCTID:150087005 ! Entire superficial temporal vein synonym: "venae temporales superficiales" RELATED LATIN [Wikipedia:Superficial_temporal_vein] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png xref: UMLS:C0226521 [Term] id: UBERON:0001658 name: middle temporal vein comment: This class was created automatically from a combination of ontologies xref: FMA:50935 ! Middle temporal vein xref: MA:0002241 ! middle temporal vein is_a: UBERON:0001671 ! temporal vein relationship: tributary_of UBERON:0001101 {source="FMA/obol"} ! external jugular vein relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein relationship: tributary_of UBERON:0001656 {source="FMA/obol"} ! retromandibular vein xref: SCTID:151400007 ! Entire middle temporal vein [Term] id: UBERON:0001659 name: transverse facial vein def: "The superficial temporal vein is a vein of the side of the head. [WP,unvetted]." [Wikipedia:Superficial_temporal_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:50938 ! Transverse facial vein xref: MA:0002247 ! transverse facial vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001101 {source="FMA/obol"} ! external jugular vein relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein relationship: tributary_of UBERON:0001656 {source="FMA/obol"} ! retromandibular vein xref: SCTID:151501009 ! Entire transverse facial vein [Term] id: UBERON:0001660 name: maxillary vein def: "The maxillary veins (internal maxillary vein in older sources) consist of a short trunk which accompanies the first part of the internal maxillary artery. It is formed by a confluence of the veins of the pterygoid plexus, and passes backward between the sphenomandibular ligament and the neck of the mandible, and unites with the superficial temporal vein to form the retromandibular vein. [WP,unvetted]." [Wikipedia:Maxillary_vein] comment: Taxon notes: in horses, a branch of the external jugular gives off the occipital and caudal auricular vein subset: uberon_slim xref: FMA:50941 ! Maxillary vein xref: MA:0002169 ! maxillary vein xref: ncithesaurus:Internal_Maxillary_Vein ! Maxillary Vein xref: OpenCyc:Mx4rvlDSc5wpEbGdrcN5Y29ycA ! maxillary vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001656 {source="FMA"} ! retromandibular vein xref: SCTID:29972009 ! Entire maxillary vein xref: UMLS:C0226524 [Term] id: UBERON:0001661 name: deep temporal vein comment: This class was created automatically from a combination of ontologies xref: FMA:50954 ! Deep temporal vein xref: MA:0002240 ! deep temporal vein xref: ncithesaurus:Deep_Temporal_Vein ! Deep Temporal Vein is_a: UBERON:0001671 ! temporal vein xref: SCTID:798000 ! Entire deep temporal vein xref: UMLS:C0226526 [Term] id: UBERON:0006197 ! auricular vein name: auricular vein def: "Any vein serving the ear region" [http://www.thefreedictionary.com/auricular+vein] comment: Taxon notes: In humans this refers to either the anterior or posterior auricular vein, passing in front of or behind the ear. This class also groups other auricular veins, including the greater, ventral, central auricular nerves. These may exhibit different branching structures. In the pig, the external jugular branches to the maxillary to the caudal auricular to the middle auricular, then onto various unique patterns is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0000033 ! head relationship: tributary_of UBERON:0001101 {source="cjm"} ! external jugular vein synonym: "vena auriculares" EXACT LATIN [] synonym: "venae auriculares" EXACT LATIN [] xref: ncithesaurus:Auricular_Vein ! Auricular Vein xref: UMLS:C2698201 [Term] id: UBERON:0001662 name: anterior auricular vein def: "The anterior auricular veins are veins which drain the anterior aspect of the external ear. [WP,unvetted]." [Wikipedia:Anterior_auricular_veins] comment: This class was created automatically from a combination of ontologies xref: FMA:50956 ! Anterior auricular vein xref: MA:0002083 ! anterior auricular vein xref: ncithesaurus:Anterior_Auricular_Vein ! Anterior Auricular Vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png is_a: UBERON:0006197 ! auricular vein relationship: tributary_of UBERON:0001656 {source="FMA"} ! retromandibular vein xref: SCTID:151602009 ! Entire anterior auricular vein synonym: "venae auriculares anteriores" RELATED LATIN [Wikipedia:Anterior_auricular_veins] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png xref: UMLS:C0226527 [Term] id: UBERON:0006199 name: posterior auricular vein def: "The posterior auricular vein begins upon the side of the head, in a plexus which communicates with the tributaries of the occipital vein and superficial temporal veins. It descends behind the auricula, and joins the posterior division of the posterior facial vein to form the external jugular. It receive the stylomastoid vein, and some tributaries from the cranial surface of the auricula." [Wikipedia:Posterior_auricular_vein] comment: AO notes: check placement of AO class synonym: "posterior auricular vein" EXACT [FMA:50851] xref: FMA:50851 ! Posterior auricular vein xref: MA:0002090 ! caudal auricular vein is_a: UBERON:0006197 ! auricular vein relationship: tributary_of UBERON:0001101 {source="FMA"} ! external jugular vein xref: ncithesaurus:Posterior_Auricular_Vein ! Posterior Auricular Vein xref: SCTID:150188002 ! Entire posterior auricular vein synonym: "venae auricularis posterior" RELATED LATIN [Wikipedia:Posterior_auricular_vein] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png xref: UMLS:C0226544 [Term] id: UBERON:0001663 name: cerebral vein def: "The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]." [Wikipedia:Cerebral_veins] comment: This class was created automatically from a combination of ontologies synonym: "venae encephali" RELATED LATIN [Wikipedia:Cerebral_veins] synonym: "venae cerebri" RELATED LATIN [Wikipedia:Cerebral_veins] xref: FMA:50981 ! Cerebral vein xref: GAID:530 ! cerebral vein xref: MA:0002096 ! cerebral vein xref: ncithesaurus:Cerebral_Vein ! Cerebral Vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9f/Gray568.png/200px-Gray568.png xref: MESH:A07.231.908.155 ! cerebral vein is_a: UBERON:0001638 ! vein xref: SCTID:244392000 ! Entire cerebral vein xref: XAO:0004160 ! cerebral vein xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/Gray568.png xref: UMLS:C0007797 [Term] id: UBERON:0001664 name: inferior cerebral vein def: "The inferior cerebral veins, of small size, drain the under surfaces of the hemispheres. Those on the orbital surface of the frontal lobe join the superior cerebral veins, and through these open into the superior sagittal sinus. Those of the temporal lobe anastomose with the middle cerebral and basal veins, and join the cavernous, sphenoparietal, and superior petrosal sinuses. [WP,unvetted]." [Wikipedia:Inferior_cerebral_veins] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:50986 ! Inferior cerebral vein xref: MA:0002097 ! inferior cerebral vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/25/Gray517.png/200px-Gray517.png is_a: UBERON:0001663 ! cerebral vein xref: SCTID:244395003 ! Entire inferior cerebral vein xref: http://upload.wikimedia.org/wikipedia/commons/2/25/Gray517.png [Term] id: UBERON:0006666 name: great cerebral vein def: "The great cerebral vein is one of the large blood vessels in the skull draining the cerebrum (brain)[WP,unvetted]" [Wikipedia:Great_cerebral_vein] synonym: "great cerebral vein of Galen" EXACT [FMA:50993] synonym: "vein of Galen" EXACT [FMA:50993] synonym: "great cerebral vein" EXACT [FMA:50993] xref: FMA:50993 ! Great cerebral vein xref: EMAPA:19311 ! great cerebral vein of Galen xref: ncithesaurus:Great_Cerebral_Vein_of_Galen ! Great Cerebral Vein of Galen xref: SCTID:244396002 ! Entire great cerebral vein is_a: UBERON:0001663 ! cerebral vein xref: UMLS:C0042448 [Term] id: UBERON:0001666 name: flexor digitorum longus def: "The Flexor digitorum longus is situated on the tibial side of the leg. At its origin it is thin and pointed, but it gradually increases in size as it descends. This muscle serves to curl the second, third, fourth, and fifth toes (flexion of phalanges II-V). [WP,unvetted]." [Wikipedia:Flexor_digitorum_longus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: BTO:0000466 xref: FMA:51071 ! Flexor digitorum longus xref: MA:0002299 ! flexor digitorum longus xref: ncithesaurus:Flexor_Digitorum_Longus ! Flexor Digitorum Longus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/92/Gray442.png/200px-Gray442.png is_a: UBERON:0001383 ! muscle of leg xref: SCTID:181703002 ! Entire flexor digitorum longus xref: UMLS:C1261048 [Term] id: UBERON:0008296 name: femoral muscle def: "Origin: anterior and lateral surfaces of femur; insertion: patella, common tendon of quadriceps femoris; innervation: femoral; action, extends leg." [BTO:0002542] comment: todo - logical definition synonym: "crureus" RELATED [BTO:0002542] synonym: "intermediate great muscle" RELATED [BTO:0002542] synonym: "intermediate vastus muscle" RELATED [BTO:0002542] synonym: "musculus vastus intermedius" RELATED [BTO:0002542] is_a: UBERON:0001383 {source="BTO"} ! muscle of leg xref: BTO:0002542 ! femoral muscle [Term] id: UBERON:0001667 name: tibialis posterior def: "The Tibialis posterior is the most central of all the leg muscles, and is located in the posterior compartment of the leg. It is the key stabilizing muscle of the lower leg. [WP,unvetted]." [Wikipedia:Tibialis_posterior_muscle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "tibialis caudalis" EXACT [] synonym: "ibialis posticus" RELATED [BTO:0000867] synonym: "posterior tibialis" RELATED [BTO:0000867] synonym: "tibialis posterior muscle" RELATED [BTO:0000867] xref: BTO:0000867 xref: FMA:51099 ! Tibialis posterior xref: MA:0002394 ! tibialis caudalis xref: ncithesaurus:Tibialis_Caudalis ! Tibialis Caudalis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/92/Gray442.png/200px-Gray442.png is_a: UBERON:0008230 ! tibialis relationship: has_muscle_insertion UBERON:0001452 {source="dbpedia"} ! distal tarsal bone 1 relationship: has_muscle_insertion UBERON:0001451 {source="dbpedia"} ! navicular bone of pes relationship: innervated_by UBERON:0001323 {source="dbpedia"} ! tibial nerve relationship: has_muscle_origin UBERON:0000979 {source="dbpedia"} ! tibia relationship: has_muscle_origin UBERON:0001446 {source="dbpedia"} ! fibula relationship: has_muscle_antagonist UBERON:0001385 {source="dbpedia"} ! tibialis anterior synonym: "musculus tibialis posterior" RELATED LATIN [Wikipedia:Tibialis_posterior_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/9/92/Gray442.png xref: SCTID:361824007 ! Entire tibialis posterior muscle xref: UMLS:C1711425 [Term] id: UBERON:0001668 name: cerebellar vein def: "Cerebellar veins are veins which drain the cerebellum. More specifically, they are: Superior cerebellar veins Inferior cerebellar veins [WP,unvetted]." [Wikipedia:Cerebellar_veins] comment: This class was created automatically from a combination of ontologies synonym: "cerebellum vein" EXACT [OBOL:automatic] synonym: "epencephalon-1 vein" EXACT [OBOL:automatic] synonym: "vein of cerebellum" EXACT [OBOL:automatic] synonym: "vein of epencephalon-1" EXACT [OBOL:automatic] xref: FMA:51227 ! Cerebellar vein xref: MA:0002093 ! cerebellar vein xref: ncithesaurus:Cerebellar_Vein ! Cerebellar Vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002037 ! cerebellum xref: SCTID:40693009 ! Entire cerebellar vein xref: UMLS:C0226601 [Term] id: UBERON:0001669 name: superior cerebellar vein def: "The superior cerebellar veins pass partly forward and medialward, across the superior vermis, to end in the straight sinus and the internal cerebral veins, partly lateralward to the transverse and superior petrosal sinuses. [WP,unvetted]." [Wikipedia:Superior_cerebellar_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "vein of superior cerebellar hemisphere" EXACT [] xref: FMA:51232 ! Superior cerebellar vein xref: MA:0002095 ! superior cerebellar vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Gray704.png/200px-Gray704.png is_a: UBERON:0001668 ! cerebellar vein xref: SCTID:64307009 ! Entire superior cerebellar vein [Term] id: UBERON:0001670 name: inferior cerebellar vein def: "The inferior cerebellar veins are of large size, end in the transverse, superior petrosal, and occipital sinuses. [WP,unvetted]." [Wikipedia:Inferior_cerebellar_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "inferior vein of cerebellar hemisphere" EXACT [] xref: FMA:51233 ! Inferior cerebellar vein xref: MA:0002094 ! inferior cerebellar vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Gray704.png/200px-Gray704.png is_a: UBERON:0001668 ! cerebellar vein xref: SCTID:69104006 ! Entire inferior cerebellar vein [Term] id: UBERON:0001671 name: temporal vein def: "The superficial temporal vein is a vein of the side of the head. [WP,unvetted]." [Wikipedia:Superficial_temporal_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:51302 ! Temporal vein xref: MA:0002239 ! temporal vein xref: ncithesaurus:Temporal_Vein ! Temporal Vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray557.png/200px-Gray557.png is_a: UBERON:0001638 ! vein xref: UMLS:C0924206 [Term] id: UBERON:0001672 name: anterior cerebral vein comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "ACeV" RELATED [] synonym: "rostral cerebral vein" RELATED [] xref: FMA:51306 ! Anterior cerebral vein xref: TAO:0001067 ! anterior cerebral vein xref: ZFA:0001067 ! anterior cerebral vein is_a: UBERON:0001663 ! cerebral vein relationship: part_of UBERON:0002200 ! vasculature of head xref: SCTID:55155007 ! Structure of anterior cerebral vein xref: XAO:0004158 ! anterior cerebral vein [Term] id: UBERON:0001620 name: central retinal artery def: "The central retinal artery (retinal artery) branches off the ophthalmic artery, running inferior to the optic nerve within its dural sheath to the eyeball. [WP,unvetted]." [Wikipedia:Central_retinal_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "central artery of retina" EXACT [] synonym: "retinal artery" EXACT [] synonym: "Zinn's artery" EXACT [] synonym: "arteria centralis retinae" RELATED [Wikipedia:Central_retinal_artery] synonym: "central artery of the retina" RELATED [Wikipedia:Central_retinal_artery] xref: FMA:49879 ! Central retinal artery xref: GAID:508 ! retinal artery xref: MA:0002038 ! retinal artery xref: ncithesaurus:Retinal_Artery ! Retinal Artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/59/Gray514_updated.png/200px-Gray514_updated.png xref: MESH:A07.231.114.765 ! retinal artery is_a: UBERON:0001637 ! artery xref: SCTID:277771001 ! Entire retinal artery synonym: "arteria centralis retinae" RELATED LATIN [Wikipedia:Central_retinal_artery] xref: http://upload.wikimedia.org/wikipedia/commons/5/59/Gray514_updated.png xref: UMLS:C0035301 [Term] id: UBERON:0001673 name: central retinal vein def: "The central retinal vein (retinal vein) is a short vein that runs through the optic nerve and drains blood from the capillaries of the retina into the larger veins outside the eye. The anatomy of the veins of the orbit of the eye varies between individuals, and in some the central retinal vein drains into the superior ophthalmic vein, and in some it drains directly into the cavernous sinus. [WP,unvetted]." [Wikipedia:Central_retinal_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "retinal vein" EXACT [] xref: FMA:51799 ! Central retinal vein xref: GAID:524 ! retinal vein xref: MA:0002213 ! retinal vein xref: ncithesaurus:Retinal_Vein ! Retinal Vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Gray572.png/200px-Gray572.png xref: MESH:A07.231.611.773 ! retinal vein is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0005486 {source="FMA/obol"} ! venous dural sinus relationship: tributary_of UBERON:0003712 {source="FMA/obol"} ! cavernous sinus xref: SCTID:280913005 ! Entire retinal vein synonym: "vena centralis retinae" RELATED LATIN [Wikipedia:Central_retinal_vein] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray572.png xref: EFO:0004271 ! retinal vein xref: UMLS:C0035327 [Term] id: UBERON:0001674 name: masseteric vein def: "A plexiform vein accompanying the masseteric artery that empty into the pterygoid venous plexus." [http://www.drugs.com/dict/masseteric-veins.html] synonym: "masseteric veins" RELATED PLURAL [] xref: FMA:52519 ! Masseteric vein xref: MA:0002167 ! masseteric vein xref: ncithesaurus:Masseteric_Vein ! Masseteric Vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001597 ! masseter muscle xref: UMLS:C0925179 [Term] id: UBERON:0013648 name: masseteric artery def: "The masseteric artery is small and passes laterally through the mandibular notch to the deep surface of the masseter muscle, which it supplies. It anastomoses with the masseteric branches of the external maxillary artery and with the transverse facial artery." [Wikipedia:Masseteric_artery] synonym: "arteria masseterica" EXACT LATIN [Wikipedia:Masseteric_artery] intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001597 ! masseter muscle relationship: branch_of UBERON:0001616 {source="FMA"} ! maxillary artery xref: FMA:49739 ! masseteric artery xref: SCTID:147864007 ! Entire masseteric artery xref: UMLS:C0226149 xref: ncithesaurus:Masseteric_Artery ! masseteric artery [Term] id: UBERON:0001675 name: trigeminal ganglion def: "A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear. Kimmel et al, 1995." [Wikipedia:Trigeminal_ganglion, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "Gasserian ganglia" RELATED PLURAL [Wikipedia:Trigeminal_ganglion] synonym: "Gasserian ganglion" EXACT [Wikipedia:Trigeminal_ganglion] synonym: "gV" RELATED [] synonym: "semilunar ganglion" EXACT [ISBN10:0471888893] synonym: "trigeminal ganglia" RELATED PLURAL [] synonym: "trigeminus ganglion" RELATED [] synonym: "trigeminal V ganglion" EXACT [MA:0001080] synonym: "5th ganglion" EXACT [ZFA:0000295] synonym: "fifth ganglion" EXACT [ZFA:0000295] synonym: "ganglion of trigeminal nerve" RELATED [BTO:0001231] synonym: "ganglion trigeminale" RELATED [BTO:0001231] synonym: "Gasser's ganglion" RELATED [BTO:0001231] xref: BTO:0001231 xref: EFO:0000903 ! trigeminal ganglion xref: FMA:52618 ! Trigeminal ganglion xref: GAID:725 ! trigeminal ganglion xref: MAT:0000511 ! trigeminal ganglion xref: TAO:0000295 ! trigeminal ganglion xref: XAO:0000427 ! gasserian ganglion xref: XAO:0000428 ! trigeminal ganglion xref: ZFA:0000295 ! trigeminal ganglion xref: ncithesaurus:Trigeminal_Ganglion ! Trigeminal Ganglion xref: VHOG:0000694 ! trigeminal V ganglion xref: MA:0001080 ! trigeminal V ganglion xref: EHDAA2:0002085 ! trigeminal V ganglion xref: BTO:0001231 ! trigeminal ganglion xref: EHDAA:2113 ! trigeminal V ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/69/Gray776.png/200px-Gray776.png xref: EMAPA:16797 ! trigeminal V of cranial of ganglion of central nervous system of nervous system of organ system xref: MESH:A08.340.390.850 ! trigeminal ganglion is_a: UBERON:0001800 {source="ncithesaurus"} ! sensory ganglion is_a: UBERON:0001714 ! cranial ganglion relationship: develops_from UBERON:0003070 {source="EHDAA2"} ! trigeminal placode relationship: develops_from UBERON:0005563 ! trigeminal neural crest xref: AAO:0011107 ! trigeminal ganglion xref: SCTID:244449009 ! Entire trigeminal ganglion synonym: "ganglion trigeminale, ganglion semilunare" RELATED LATIN [Wikipedia:Trigeminal_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/6/69/Gray776.png property_value: external_definition "A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000295", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0040995 [Term] id: UBERON:0005902 name: occipital region def: "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles." [TAO:0001414, UBERONREF:0000007] comment: TODO - check synonym: "basicranial region" EXACT [ZFA:0001414] synonym: "occipital part of head" EXACT [FMA:49187] xref: XAO:0003173 ! occipital region xref: TAO:0001414 ! occipital region xref: ZFA:0001414 ! occipital region is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0003128 ! cranium xref: AAO:0010199 ! occipital region xref: SCTID:362618001 ! Entire occipital region xref: FMA:49187 ! occipital part of head property_value: external_definition "An anatomical cluster that is located in the posterior region of the neurocranium and forms the margin of the foramen margin and occipital condyles.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010199", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occiptal condyle.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001414", date_retrieved="2012-08-14", source="TAO:MAH"} synonym: "back of head" RELATED [FMA:49187] synonym: "occipital region of head" EXACT [FMA:49187] [Term] id: UBERON:0001676 name: occipital bone def: "A saucer-shaped membrane bone situated at the back and lower part of the cranium, is trapezoid in shape and curved on itself. It is pierced by a large oval aperture, the foramen magnum, through which the cranial cavity communicates with the vertebral canal." [Wikipedia:Occipital_bone] comment: Taxon notes: fusion of basi-, exo- and supra-occipitals (and maybe tabular)[Kardong]. Development notes: formed from the sclerotome of the occipital somites[PMID:11523816]. It is not present in living or fossil agnathans or cartilaginous fishes, but appears to have arisen in parallel in many bony fishes. Incorporation of the occipital ver- tebrae into the skull was associated with the an- nexation of the upper part of the spinal cord into the brain, together with the first 2 spinal nerves as cranial nerves XI and XII[PMID:11523816] subset: uberon_slim synonym: "occipital squama" RELATED [] synonym: "occipital complex" RELATED [http://palaeos.com/vertebrates/bones/braincase/occiput.html] xref: FMA:52735 ! Occipital bone xref: GAID:227 ! occipital bone xref: MA:0001468 ! occipital bone xref: ncithesaurus:Occipital_Bone ! Occipital Bone xref: OpenCyc:Mx4rwQtsiZwpEbGdrcN5Y29ycA ! occipital bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/27/Gray194.png/200px-Gray194.png xref: EMAPA:25112 ! occipital bone xref: MESH:A02.835.232.781.572 ! occipital bone xref: SCTID:181796003 ! Entire occipital bone is_a: UBERON:0010428 {source="FMA"} ! flat bone relationship: overlaps UBERON:0003113 {notes="interparietal (postparietal)"} ! dermatocranium relationship: overlaps UBERON:0002241 {source="MA-modified", notes="basi paired exo and supra occipital bones"} ! chondrocranium relationship: part_of UBERON:0001703 {source="FMA"} ! neurocranium relationship: part_of UBERON:0005902 {source="FMA"} ! occipital region relationship: develops_from UBERON:0003089 {source="PMID:11523816"} ! sclerotome relationship: connected_to UBERON:0001092 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! cervical vertebra 1 relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone synonym: "os occipitale" RELATED LATIN [Wikipedia:Occipital_bone] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray194.png xref: UMLS:C0028784 [Term] id: UBERON:0001677 name: sphenoid bone def: "an unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended." [Wikipedia:Sphenoid_bone] comment: part of viscerocranium in FMA, part of chondrocranium in MA subset: uberon_slim synonym: "butterfly bone" RELATED [Wikipedia:Sphenoid_bone] synonym: "os sphenoidale" RELATED [Wikipedia:Sphenoid_bone] synonym: "os sphenoidum" RELATED [Wikipedia:Sphenoid_bone] synonym: "sphenoid" EXACT [] synonym: "sphenoidal bone" EXACT [] synonym: "sphenoid complex" RELATED [] synonym: "os sphenoidale" EXACT LATIN [FMA:TA, FMA:52736] xref: SCTID:272676008 ! Entire sphenoid bone xref: FMA:52736 ! Sphenoid bone xref: GAID:230 ! sphenoid bone xref: MA:0001472 ! sphenoid bone xref: EMAPA:18340 ! sphenoid xref: ncithesaurus:Sphenoid_Bone ! Sphenoid Bone xref: OpenCyc:Mx4rwAU9XpwpEbGdrcN5Y29ycA ! sphenoid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Illu_cranial_bones2.jpg/200px-Illu_cranial_bones2.jpg xref: MESH:A02.835.232.781.802 ! sphenoid bone is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone relationship: overlaps UBERON:0003113 {notes="pterygoid process"} ! dermatocranium relationship: overlaps UBERON:0002241 {notes="orbito pre and basi sphenoid"} ! chondrocranium relationship: overlaps UBERON:0008895 {notes="alisphenoid"} ! splanchnocranium relationship: part_of UBERON:0011156 {source="FMA"} ! facial skeleton relationship: develops_from UBERON:0009193 {source="cjm"} ! sphenoid bone cartilage condensation relationship: connected_to UBERON:0000209 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tetrapod frontal bone relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid relationship: connected_to UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! occipital bone relationship: connected_to UBERON:0002396 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vomer synonym: "os sphenoidale" RELATED LATIN [Wikipedia:Sphenoid_bone] xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg xref: UMLS:C0037884 [Term] id: UBERON:0008828 name: presphenoid bone def: "The anterior part of the body of the sphenoid bone in front of the basisphenoid. It is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult." [http://www.thefreedictionary.com/Presphenoid+bone, Wikipedia:Ossification_of_sphenoid#Presphenoid] comment: todo - account for developmental change is_a: UBERON:0011164 {source="MA"} ! neurocranium bone relationship: part_of UBERON:0001677 {source="MA"} ! sphenoid bone relationship: part_of UBERON:0003111 {source="Kardong"} ! sphenoid region xref: MA:0001470 ! presphenoid bone xref: SCTID:95949009 ! presphenoidal bone synonym: "presphenoidal bone" EXACT [SCTID:95949009] [Term] id: UBERON:0009470 name: postsphenoidal bone def: "the posterior portion of the sphenoid bone developed in five separate parts consisting of a central basisphenoid, the two alisphenoids, and the two medial pterygoid laminae." [http://www.merriam-webster.com/dictionary/postsphenoid, Wikipedia:Ossification_of_sphenoid#Postsphenoid] is_a: UBERON:0011164 {source="MA"} ! neurocranium bone relationship: part_of UBERON:0001677 {source="cjm"} ! sphenoid bone xref: SCTID:95950009 ! postsphenoidal bone [Term] id: UBERON:0001678 name: temporal bone def: "The temporal bones are situated at the sides and base of the skull, and lateral to the temporal lobes of the cerebrum." [Wikipedia:Temporal_bone] comment: The temporal bone consists of four parts: * Squama temporalis * Mastoid portion * Petrous portion (Petrosal ridge) * Tympanic part[WP]. AO notes: Note the Temporal bone is not explicitly categorized to a part of the cranium in FMA. Taxon notes: fusion of squamosal + angular (tympanic annulus) [derm.] + petrosal (prootic + opisthotic)[chond.] + styloid process[splanc.] // In many mammals, as in humans, the petrosal, ectotympanic and squamosal bones synostose to form the temporal bone subset: uberon_slim xref: EHDAA:6035 ! temporal bone xref: FMA:52737 ! Temporal bone xref: GAID:232 ! temporal bone xref: VHOG:0000800 ! temporal bone xref: MA:0001476 ! temporal bone xref: OpenCyc:Mx4rvbkAk5wpEbGdrcN5Y29ycA xref: ncithesaurus:Temporal_Bone ! Temporal Bone xref: OpenCyc:Mx4rvbkAk5wpEbGdrcN5Y29ycA ! temporal bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Illu_cranial_bones2.jpg/200px-Illu_cranial_bones2.jpg xref: EMAPA:17682 ! temporal bone of chondrocranium xref: EMAPA:18020 ! temporal bone of vault of skull xref: MESH:A02.835.232.781.885 ! temporal bone is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone relationship: overlaps UBERON:0003113 {notes="squamosal plus angular", notes="temporal series"} ! dermatocranium relationship: overlaps UBERON:0002241 {notes="petrosal"} ! chondrocranium relationship: overlaps UBERON:0008895 {notes="styloid process"} ! splanchnocranium xref: SCTID:181795004 ! Entire temporal bone synonym: "os temporale" RELATED LATIN [Wikipedia:Temporal_bone] xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: UMLS:C0039484 [Term] id: UBERON:0004747 name: supraoccipital bone alt_id: UBERON:0005237 comment: Taxon notes (via VHOG): See Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution, Fourth Edition (2006) McGraw-Hill, p.237 Table 7.1 subset: vertebrate_core synonym: "supraoccipital" EXACT [VHOG:0001150] xref: ZFA:0000595 ! supraoccipital xref: VHOG:0001150 ! supraoccipital bone xref: MA:0001474 ! supraoccipital bone is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0002241 ! chondrocranium relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0005902 {source="TAO"} ! occipital region relationship: part_of UBERON:0001676 {source="Kardong", gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! occipital bone xref: SCTID:95947006 ! Entire supraoccipital bone xref: TAO:0000595 ! supraoccipital relationship: develops_from UBERON:0011162 ! supraoccipital bone cartilaginous condensation property_value: external_definition "The supraoccipital ties the occiput to the dermal skull table.[Palaeos]" xsd:string {date_retrieved="2012-09-06", source="http://palaeos.com/vertebrates/bones/braincase/occiput.html"} property_value: external_definition "a bone on the dorsal side of the great foramen of the skull, usually forming a part of the occipital in the adult, but distinct in the young..[TFD]" xsd:string {date_retrieved="2012-09-06", source="http://www.thefreedictionary.com/Supraoccipital"} property_value: external_definition "Endochondral bone that is located at the dorsal part of the occipital region of the cranium or the dorso-posterior part of the skull. It forms the dorsal margin of the foramen magnum. Commonly the supraoccipital articulates with the parietals anteriorly, the epiotics laterally, and the exoccipitals posteroventrally. The supraoccipital is an unpaired median bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000595", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: part_of neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000595", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps supraoccipital-parietal joint (TAO:0005264)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000595", date_retrieved="2012-08-14"} synonym: "acrinial@fr" RELATED [TAO:0000595] synonym: "acrinioste@fr" RELATED [TAO:0000595] synonym: "supraoccipital@fr" RELATED [TAO:0000595] [Term] id: UBERON:0011162 name: supraoccipital cartilaginous condensation synonym: "supra-occipital cartilage condensation" EXACT [] synonym: "supraoccipital cartilage condensation" EXACT [EMAPA:18341] synonym: "non-squamous part of supraoccipital bone" RELATED [EMAPA:18341] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0004747 ! supraoccipital bone relationship: part_of UBERON:0002241 ! chondrocranium relationship: develops_from UBERON:0011163 ! supraoccipital pre-cartilage condensation xref: EMAPA:18341 ! supraoccipital cartilage condensation def: "A cartilaginous condensation that develops_into a supraoccipital bone." [OBOL:automatic] [Term] id: UBERON:0011163 name: supraoccipital pre-cartilage condensation synonym: "supra-occipital pre-cartilage condensation" EXACT [EHDAA2:0001963] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0004747 ! supraoccipital bone relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium relationship: develops_from UBERON:0009617 {source="EHDAA2-inferred"} ! head paraxial mesoderm xref: EHDAA2:0001963 ! supra-occipital pre-cartilage condensation xref: EHDAA:9534 ! supra-occipital pre-cartilage condensation def: "A pre-cartilage condensation that develops_into a supraoccipital bone." [OBOL:automatic] [Term] id: UBERON:0001692 name: basioccipital bone def: "One of the bones of the occiput, the part of the skull which articulates with the spine. The basioccipital is located (if present) ventral to the foramen magnum. It often rests on or articulates with the basisphenoid, as well as meeting the exoccipitals. The basioccipital usually forms most (sometimes all) of the occipital condyle(s) and the ventral margin of the foramen magnum." [Wikipedia:Basilar_part_of_occipital_bone, http://palaeos.com/vertebrates/glossary/glossaryB.html] comment: TODO - check FMA subset: uberon_slim subset: vertebrate_core synonym: "basioccipital bone" EXACT [] synonym: "basioccipital" EXACT [] synonym: "basi-occipital" EXACT [] synonym: "basilar part of occipital bone" EXACT [] xref: AAO:0000039 ! basioccipital xref: FMA:52858 ! Basilar part of occipital bone xref: VHOG:0001152 ! basioccipital bone xref: MA:0001462 ! basioccipital bone xref: TAO:0000472 ! basioccipital xref: ZFA:0000472 ! basioccipital xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c4/Parsbasilaris%28young%29.PNG/200px-Parsbasilaris%28young%29.PNG xref: EMAPA:18705 ! basioccipital bone is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0005902 {source="TAO"} ! occipital region relationship: part_of UBERON:0001676 {source="Kardong", gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! occipital bone relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium relationship: part_of UBERON:0002241 ! chondrocranium relationship: develops_from UBERON:0006209 ! basioccipital cartilage condensation xref: SCTID:138976007 ! Entire basilar part of occipital bone synonym: "pars basilaris ossis occipitalis" RELATED LATIN [Wikipedia:Basilar_part_of_occipital_bone] xref: http://upload.wikimedia.org/wikipedia/commons/c/c4/Parsbasilaris%28young%29.PNG property_value: external_definition "An unpaired medial bone contributing to the ventral margin of the foramen magnum that extends into the floor of the brain cavity. It can contribute to the centromedial portion of the occipital condyle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000039", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Chondral bone that articulates with the exoccipitals dorsally, the prootics anteriorly, the parasphenoid ventrally, and the first free vertebra posteriorly. The basioccipital forms the floor of the foramen magnum. The basioccipital is an unpaired medial bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000472", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: part_of neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000472", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps parasphenoid-basioccipital joint (TAO:0001832)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000472", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps basioccipital-exoccipital joint (TAO:0002038)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000472", date_retrieved="2012-08-14"} synonym: "basinial@fr" RELATED [TAO:0000472] synonym: "basinioste@fr" RELATED [TAO:0000472] synonym: "basioccipital@fr" RELATED [TAO:0000472] property_value: external_comment "In some teleosts the anterior vertebral centra fuse to the basioccipital forming a monopartite occipital condyle.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000472", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0001693 name: exoccipital bone def: "Paired cartilage bone that bears a large foramen (lateral occipital foramen). Contacts the supraoccipital dorsally, the epiotic laterally and the basioccipital ventrally. Forms the posterior hind margin of the cranium and borders the lateral and posterior margins of the forum (foramen) magnum." [ZFIN:curator, Wikipedia:Lateral_parts_of_occipital_bone] comment: TODO - check FMA - currently we place this as both of a zone of bone organ and an (endochondral) bone. Removed endochondral bone classification for now, violates disjointness axiom subset: uberon_slim subset: vertebrate_core synonym: "pars lateralis" RELATED [Wikipedia:Lateral_parts_of_occipital_bone] synonym: "exoccipital" EXACT [FMA:52859] synonym: "lateral part of occipital bone" EXACT [FMA:52859] xref: AAO:0000147 ! exoccipital xref: FMA:52859 ! lateral part of occipital bone xref: VHOG:0001151 ! exoccipital bone xref: MA:0001464 ! exoccipital bone xref: TAO:0000661 ! exoccipital xref: ZFA:0000661 ! exoccipital xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bf/Gray131.png/200px-Gray131.png xref: EMAPA:18708 ! exoccipital bone is_a: UBERON:0002513 {source="ZFA"} ! endochondral bone relationship: part_of UBERON:0005902 {source="TAO"} ! occipital region relationship: part_of UBERON:0001676 {source="Kardong", gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! occipital bone relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium xref: SCTID:139279001 ! Entire lateral part of occipital bone relationship: develops_from UBERON:0010752 ! exoccipital cartilage condensation relationship: develops_from UBERON:0009635 {source="ZFA"} ! parachordal cartilage synonym: "pars lateralis" RELATED LATIN [Wikipedia:Lateral_parts_of_occipital_bone] xref: http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray131.png property_value: external_definition "Endochondral bone that forms the posterior end of the neurocranium and the margin of the foramen magnum. In addition, this bone forms either part of or all or the occipital condyle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000147", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Endochondral bone that articulates with the epiotic dorsally, the pterotic and intercalar laterally and the basioccipital medio-ventrally. The exoccipitals form the lateral borders of the foramen magnum and houses the foramina for the passage of the vagus and glossopharyngeal nerves, X and IX respectively. The exoccipital is a paired bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000661", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from occipital arch cartilage (TAO:0001504)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000661", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: part_of neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000661", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps prootic-exoccipital joint (TAO:0002034)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000661", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps basioccipital-exoccipital joint (TAO:0002038)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000661", date_retrieved="2012-08-14"} synonym: "exoccipitals" EXACT PLURAL [TAO:0000661] synonym: "exoccipital@fr" RELATED [TAO:0000661] synonym: "occipital latcéral@fr" RELATED [TAO:0000661] synonym: "pleurinial@fr" RELATED [TAO:0000661] synonym: "pleurinioste@fr" RELATED [TAO:0000661] property_value: external_comment "In some teleosts the exoccipital dorsally contacts the supraoccipital directly or through connective tissue.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000661", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0001694 name: petrous part of temporal bone def: "The petrous portion of the temporal bone or pyramid is pyramidal and is wedged in at the base of the skull between the sphenoid and occipital bones. Directed medially, forward, and a little upward, it presents for examination a base, an apex, three surfaces, and three angles, and contains, in its interior, the essential parts of the organ of hearing. The petrous portion is among the most basal elements of the skull and forms part of the endocranium.[WP,unvetted]." [Wikipedia:Petrous_part_of_the_temporal_bone] comment: derivative of prootic and opisthotic subset: uberon_slim synonym: "pars petrosa (os temporale)" EXACT [FMA:52871] synonym: "petromastoid part of temporal bone" EXACT [FMA:52871] synonym: "petrosal bone" EXACT [FMA:52871] synonym: "petrous bone" EXACT [FMA:52871] synonym: "pars petrosa ossis temporalis" EXACT [] synonym: "temporal bone petrous part" EXACT [] synonym: "petrosal" BROAD [VHOG:0001553] xref: FMA:52871 ! Petrous part of temporal bone xref: GAID:234 ! petrous bone xref: MA:0001477 ! temporal bone petrous part xref: EHDAA2:0001452 ! petrous part of temporal bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/96/Gray137.png/200px-Gray137.png xref: EMAPA:17683 ! petrous part xref: MESH:A02.835.232.781.885.681 ! petrous bone is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001678 ! temporal bone relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium xref: SCTID:361733004 ! Entire petrous part of temporal bone xref: ncithesaurus:Ciliary_Process ! Ciliary Process xref: VHOG:0001553 ! temporal bone petrous part property_value: external_definition "The petrosal bone arises from the two otic bones on the lateral wall of the chondrocranium and encases the inner ear of mammals. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, p.258, see_Liem_KF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001553", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C1261761 [Term] id: UBERON:0001695 name: squamous part of temporal bone def: "A bone which is fused with the temporal bone in many mammals and forms part of the cheek region articulating with quadrate and pterygoid in other vertebrates." [MP:0004423, Wikipedia:Squama_temporalis, Wikipedia:Squamosal_bone] comment: Taxon notes: The squamosal bone, which is homologous with the squama, and forms the side of the cranium in many bony fish and tetrapods. Primitively, it is a flattened plate-like bone, but in many animals it is narrower in form, for example, where it forms the boundary between the two temporal fenestrae of diapsid reptiles. Editor notes: consider separate class for squamosal OR making squamosal the primary label synonym: "pars squamosa (os temporale)" EXACT [] synonym: "squamosal bone" EXACT [] synonym: "squamous bone" EXACT [] synonym: "squama" RELATED [] synonym: "squama temporalis" EXACT [Wikipedia:Squama_temporalis] synonym: "squamosal" EXACT [AAO:0000574] synonym: "squamosal bone" EXACT [MA:0001473] synonym: "temporal bone squamous part" EXACT [VHOG:0001561] xref: FMA:52883 ! Squamous part of temporal bone xref: MA:0001473 ! squamosal bone xref: AAO:0000574 ! squamosal xref: EMAPA:18021 ! squamous part of temporal bone of vault of skull xref: VHOG:0001561 ! temporal bone squamous part is_a: UBERON:0002514 {source="EHDAA2-inferred"} ! intramembranous bone relationship: part_of UBERON:0003113 {source="Kardong", notes="temporal series"} ! dermatocranium relationship: part_of UBERON:0004339 {source="EHDAA2", source="PMID:11523816"} ! vault of skull relationship: part_of UBERON:0001678 {notes="see comments"} ! temporal bone relationship: develops_from UBERON:0010751 ! squamous part of temporal bone primordium xref: SCTID:138672006 ! Entire squamous part of temporal bone synonym: "squama temporalis" RELATED LATIN [Wikipedia:Squama_temporalis] xref: http://upload.wikimedia.org/wikipedia/commons/f/fd/Gray144.png xref: http://upload.wikimedia.org/wikipedia/commons/e/eb/Skull_synapsida_1.png property_value: external_definition "Paired, intramembranous bones that lie at the posterolateral margins of the skull. Lateral and dorsal to the quadrate.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000574", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "The squamosal bone is part of the dermatocranium in early tetrapods and becomes part of the mammalian occipital and temporal bones. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, p.246, see_Liem_KF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001561", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0010751 ! squamous part of temporal bone primordium name: squamous part of temporal bone primordium synonym: "squamosal bone primordium" EXACT [] synonym: "squamosal primordium" EXACT [] xref: EHDAA2:0001907 ! squamous part of temporal bone primordium xref: EHDAA:9536 ! squamous part primordium is_a: UBERON:0001048 ! primordium relationship: develops_from UBERON:0007213 ! mesenchyme derived from head neural crest relationship: part_of UBERON:0004339 {source="EHDAA2", source="PMID:11523816"} ! vault of skull [Term] id: UBERON:0011241 name: ethmoid region def: "the most anterior region of the braincase. Provides structural support for peripheral olfactory organ." [http://palaeos.com/vertebrates/bones/braincase/ethmoid.html, UBERONREF:0000007] comment: Usage notes: currently this is not restricted to skeletal elements, unlike UBERONREF:0000007 xref: AAO:0000986 ! ethmoid region is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0003112 ! olfactory region relationship: has_developmental_contribution_from UBERON:0005945 ! neurocranial trabecula [Term] id: UBERON:0011242 name: ethmoid cartilage def: "Region between capsules formed by anterior tips of neurocranial trabeculae." [ISBN10:0073040584] comment: We assume the AAO structure is cartilage synonym: "ethmoid plate" RELATED [TAO:0001405] is_a: UBERON:0003932 {source="TAO"} ! cartilage element of chondrocranium relationship: overlaps UBERON:0001703 {source="TAO"} ! neurocranium relationship: part_of UBERON:0011241 {source="AAO"} ! ethmoid region relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium relationship: develops_from UBERON:0005945 {source="Kardong"} ! neurocranial trabecula xref: AAO:0010134 ! ethmoid plate xref: TAO:0001405 ! ethmoid cartilage xref: ZFA:0001405 ! ethmoid cartilage property_value: external_definition "Anterior wall of the braincase.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010134", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Chondrocranium cartilage that is initially plate-like and formed from the anterior fusion of the trabecula crani. The ethmoid cartilage is paired.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001405", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "ethmoid cartilages" EXACT PLURAL [TAO:0001405] xref: EFO:0003685 ! ethmoid cartilage [Term] id: UBERON:0011629 name: supratemporal bone synonym: "supratemporal" EXACT [] is_a: UBERON:0002514 ! intramembranous bone relationship: part_of UBERON:0003113 {source="Kardong", notes="temporal series"} ! dermatocranium [Term] id: UBERON:0011630 name: intertemporal bone synonym: "intertemporal" EXACT [] is_a: UBERON:0002514 ! intramembranous bone relationship: part_of UBERON:0003113 {source="Kardong", notes="temporal series"} ! dermatocranium [Term] id: UBERON:0011631 name: tabular bone synonym: "tabular" EXACT [] is_a: UBERON:0002514 ! intramembranous bone relationship: part_of UBERON:0003113 {source="Kardong", notes="temporal series"} ! dermatocranium [Term] id: UBERON:0001679 name: ethmoid bone def: "a bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP]" [Wikipedia:Ethmoid_bone] comment: AO notes: Note the WP states the Neurocranium contains the ethmoid bone, both MA and FMA place the ethmoid as part of the viscerocranium. FMA also has it in neurocranium (via basicranium). Ideally we would have non-overlapping divisions of the skull, but for now we follow FMA. Taxon notes: todo - homology e.g. mesethmoid of teleost subset: uberon_slim synonym: "os ethmoidale" EXACT [Wikipedia:Ethmoid] synonym: "ethmoid" EXACT [FMA:52740] synonym: "ethmoidal bone" EXACT [MP:0000101] xref: FMA:52740 ! ethmoid xref: GAID:212 ! ethmoid bone xref: MA:0001483 ! ethmoid bone xref: ncithesaurus:Ethmoid_Bone ! Ethmoid Bone xref: VHOG:0001317 ! ethmoid bone xref: OpenCyc:Mx4rvuUPh5wpEbGdrcN5Y29ycA ! ethmoid xref: BTO:0004140 ! ethmoid bone xref: EMAPA:19018 ! ethmoid bone xref: MESH:A02.835.232.781.292 ! ethmoid bone is_a: UBERON:0002513 {source="Kardong"} ! endochondral bone relationship: part_of UBERON:0011156 ! facial skeleton relationship: part_of UBERON:0002517 ! basicranium relationship: part_of UBERON:0011241 ! ethmoid region relationship: develops_from UBERON:0006227 {evidence="definitional"} ! ethmoid bone primordium synonym: "os ethmoidale" EXACT LATIN [FMA:TA, FMA:52740] xref: SCTID:272674006 ! Entire ethmoid bone relationship: connected_to UBERON:0002396 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vomer relationship: connected_to UBERON:0000209 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tetrapod frontal bone relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg property_value: external_definition "A light spongy bone located between the eye sockets, forming part of the walls and septum of the superior nasal cavity, and containing perforations for the passage of olfactory nerve fibers. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001317", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/ethmoid+bone", source="http://bgee.unil.ch/"} property_value: homology_notes "The ethmoid region of the chondrocranium and the nasal capsules, which were largely unossified in early tetrapods and ancestral amniotes, are represented in mammals by the ethmoid and turbinates bones, respectively.[well established][VHOG]" xsd:string {external_class="VHOG:0001317", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.259", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "ethmoidal" xsd:string xref: UMLS:C0015027 [Term] id: UBERON:0006227 name: ethmoid bone primordium subset: emapa_ehdaa2 comment: Consider obsoleting, the ethmoid is endochondral? xref: EMAPA:18023 ! ethmoid bone primordium xref: EHDAA2:0000456 ! ethmoid bone primordium xref: EHDAA:8363 ! ethmoid bone primordium is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0011241 {source="AAO"} ! ethmoid region relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium relationship: develops_into UBERON:0001679 ! ethmoid relationship: develops_from UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest [Term] id: UBERON:0006332 ! nasal capsule name: nasal capsule def: "an embryonic cartilaginous frame, the nasal capsule, an evolutionary-conserved structure composed of ventral and dorsal components: the mesethmoid and ectethmoid cartilages, respectively.[PMID]." [PMID:21270050] comment: Taxon notes: In most mammals, the nasal capsule remains unossified, except in mammals where the ethmoid portion ossifies to form the turbinates[Kardong]. In avians, the mesethmoid supports upper beak formation, whereas the ectethmoid comprises elements of the olfactory system, including the lamina cribosa, the crista galli apophysis and the conchae. Editor's note - consider splitting this class. Developing cartilage in mammals? Connective tissue sheath in TAO. Structure that has both respiratory and olfactory functions and lies anterior to the braincase, in the foremost section of the cranium[AAO]. Cartilaginous envelope containing the nasal organ[FishBase] Multi-tissue structure composed of connective tissue that surrounds, the internal portions of the olfactory epithelium[ZFA]. Avian def: The nasal capsule is dorsoventrally divided into two parts: the upper part, the ectethmoid, serves olfaction and is composed of the lamina cribosa, the crista galli apophysis and the conchae. The lower part, the mesethmoid, is a thick cartilage bar extending from the corpus sphenoidalis to the rostral extremity of the nose (Fig. 1A-B􏰐). In the avian embryo, the mesethmoid constitutes the cartilage primordium of the upper beak synonym: "cartilaginous nasal capsule" RELATED [] subset: vertebrate_core xref: ZFA:0005507 ! nasal capsule xref: MA:0000283 ! nasal capsule xref: AAO:0000313 ! nasal capsule xref: EMAPA:17852 ! nasal capsule is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0000004 {source="MA"} ! olfactory apparatus xref: TAO:0002035 ! nasal capsule property_value: external_definition "Structure that has both respiratory and olfactory functions and lies anterior to the braincase, in the foremost section of the cranium.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000313", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Multi-tissue structure that is the connective tissue sheath that surrounds, except for external opening(s) in adult, the olfactory epithelium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002035", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_comment "Development information from Brian Hall, Bones and Cartilage: Developmental Skeletal Biology.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002035", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0010892 ! mesethmoid element name: mesethmoid element def: "region of the nasal capsule that forms septum between nasal capsules and usually remains unossified in mammals" [ISBN10:0073040584] synonym: "ventral nasal capsule" EXACT [PMID:21270050] synonym: "mesethmoid" RELATED [AAO:0000303] is_a: UBERON:0004765 ! skeletal element relationship: develops_from UBERON:0005945 {source="TAO"} ! neurocranial trabecula relationship: part_of UBERON:0011241 {source="Kardong"} ! ethmoid region xref: AAO:0000303 ! mesethmoid property_value: external_definition "Endochondral ossification of the anteromedial portion of the braincase.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000303", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000303", date_retrieved="2012-06-20"} [Term] id: UBERON:0011238 name: mesethmoid bone def: "Endochondral bone that extends forward from the frontal bones and articulates posterolaterally with the lateral ethmoids and the vomer and parasphenoid ventrally. The mesethmoid is an unpaired median bone." [TAO:0000323] comment: absent in primitive mammals, ungulates, amphibians, reptiles/birds[Kardong] synonym: "ethmoid" RELATED [TAO:0000323] is_a: UBERON:0002513 {source="TAO"} ! endochondral bone is_a: UBERON:0010892 ! mesethmoid element relationship: part_of UBERON:0002241 {source="TAO"} ! chondrocranium relationship: develops_from UBERON:0005945 {source="TAO"} ! neurocranial trabecula relationship: overlaps UBERON:0001703 {source="TAO"} ! neurocranium relationship: part_of UBERON:0011241 {source="Kardong"} ! ethmoid region xref: TAO:0000323 ! mesethmoid bone xref: ZFA:0000323 ! mesethmoid bone synonym: "dermethmocïde@fr" RELATED [TAO:0000323] synonym: "mcésethmocïde@fr" RELATED [TAO:0000323] [Term] id: UBERON:0011244 name: perpendicular plate of ethmoid def: "The perpendicular plate of the ethmoid bone (vertical plate) is a thin, flattened lamina, polygonal in form, which descends from the under surface of the cribriform plate, and assists in forming the septum of the nose; it is generally deflected a little to one or other side. The anterior border articulates with the spine of the frontal bone and the crest of the nasal bones. The posterior border articulates by its upper half with the sphenoidal crest, by its lower with the vomer. The inferior border is thicker than the posterior, and serves for the attachment of the septal cartilage of the nose. The surfaces of the plate are smooth, except above, where numerous grooves and canals are seen; these lead from the medial foramina on the cribriform plate and lodge filaments of the olfactory nerves." [Wikipedia:Perpendicular_plate_of_ethmoid_bone] synonym: "lamina perpendicularis ossis ethmoidalis" RELATED [Wikipedia:Perpendicular_plate_of_ethmoid_bone] synonym: "vertical plate of the ethmoid bone" RELATED [Wikipedia:Perpendicular_plate_of_ethmoid_bone] synonym: "perpendicular plate of the ethmoid bone" RELATED [Wikipedia:Perpendicular_plate_of_ethmoid_bone] synonym: "lamina perpendicularis (os ethmoidale)" EXACT [FMA:52891] synonym: "lamina perpendicularis of ethmoid bone" EXACT [FMA:52891] synonym: "perpendicular plate" BROAD [EMAPA:25114] is_a: UBERON:0005913 {source="cjm"} ! zone of bone organ relationship: part_of UBERON:0001679 {source="FMA"} ! ethmoid bone xref: FMA:52891 ! perpendicular plate of ethmoid xref: EMAPA:25114 ! perpendicular plate xref: SCTID:369005006 ! Entire lamina perpendicularis of ethmoid bone [Term] id: UBERON:0001706 name: nasal septum def: "The nasal septum separates the left and right airways in the nose, dividing the two nostrils. It is depressed by the Depressor septi nasi muscle. [WP,unvetted]." [Wikipedia:Nasal_septum] comment: We follow AAO in making this part of the nasal skeleton synonym: "columella nasi" RELATED [Wikipedia:Nasal_septum] synonym: "nasi columella" RELATED [Wikipedia:Nasal_septum] synonym: "septal cartilage" RELATED [Wikipedia:Nasal_septum] synonym: "septum mobile nasi" RELATED [Wikipedia:Nasal_septum] synonym: "septum nasi" RELATED [Wikipedia:Nasal_septum] synonym: "septum of the nose" RELATED [Wikipedia:Nasal_septum] subset: uberon_slim xref: EHDAA:6809 ! nasal septum xref: FMA:54375 ! Nasal septum xref: GAID:115 ! nasal septum xref: VHOG:0000017 ! nasal septum xref: MA:0000285 ! nasal septum xref: OpenCyc:Mx4rv7e-k5wpEbGdrcN5Y29ycA xref: ncithesaurus:Nasal_Septum ! Nasal Septum xref: OpenCyc:Mx4rv7e-k5wpEbGdrcN5Y29ycA ! nasal septum xref: EHDAA2:0001234 ! nasal septum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Gray854.png/200px-Gray854.png xref: EMAPA:17608 ! nasal septum xref: MESH:A02.165.639 ! nasal septum is_a: UBERON:0003037 ! septum relationship: part_of UBERON:0006813 {source="AAO"} ! nasal skeleton relationship: part_of UBERON:0011241 {source="AAO"} ! ethmoid region relationship: part_of UBERON:0000004 ! olfactory apparatus relationship: develops_from UBERON:0009714 {source="EHDAA2-abduced"} ! intermaxillary process xref: AAO:0010135 ! nasal septum xref: EHDAA2:0004104 ! nasal septum xref: SCTID:181197004 ! Entire nasal septum xref: AAO:0000559 ! septum nasi synonym: "septum nasi" RELATED LATIN [Wikipedia:Nasal_septum] xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Gray854.png property_value: external_definition "Medial, vertical plate that separates the nasal capsules.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000559", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Medial vertical wall between nasal capsules.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010135", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "A median dividing wall, sagitally directed, which divides the nasal cavity into the right and the left nasal fossae. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000017", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Whatever the common ancestor of the lamprey and gnathostomes may have looked like, it most likely possessed a neural-crest-derived premandibular ectomesenchyme closely associated with the NHP. Invention of the jaw subsequently required a space for the nasal septum and maxillary process to develop, which might have been provided by subdivision of the NHP into the nasal placode and the hypophysis (diplorhiny, the state of bilaterally separated nasal openings, would also have been a prerequisite for this).[well established][VHOG]" xsd:string {external_class="VHOG:0000017", ontology="VHOG", source="DOI:10.1098/rstb.2001.0976 Kuratani S\, Nobusada Y\, Horigome N\, Shigetani Y\, Embryology of the lamprey and evolution of the vertebrate jaw: insights from molecular and developmental perspectives. Philosophical transactions of the Royal Society of London (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0027432 [Term] id: UBERON:0001680 name: lacrimal bone def: "the smallest and most fragile bone of the face, is situated at the front part of the medial wall of the orbit. It has two surfaces and four borders. In early lobe-finned fishes and ancestral tetrapods, the lacrimal bone is a relatively large and robust bone, running from the orbit to the nostrils. It forms part of the side of the face, between the nasal bones and the maxilla. In primitive forms, it is often accompanied by a much smaller septomaxilla bone, lying immediately behind the nasal opening, but this is lost in most modern species. The lacrimal bone is often smaller in living vertebrates, and is no longer always directly associated with the nasal opening, although it retains its connection with the orbit. The bone is entirely absent in living amphibians, as well as some reptilian species." [Wikipedia:Lacrimal_bone] comment: In early lobe-finned fishes and ancestral tetrapods, the lacrimal bone is a relatively large and robust bone, running from the orbit to the nostrils. It forms part of the side of the face, between the nasal bones and the maxilla. In primitive forms, it is often accompanied by a much smaller septomaxilla bone, lying immediately behind the nasal opening, but this is lost in most modern species. The lacrimal bone is often smaller in living vertebrates, and is no longer always directly associated with the nasal opening, although it retains its connection with the orbit. The bone is entirely absent in living amphibians, as well as some reptilian species[WP, ISBN 0-03-910284-X] subset: uberon_slim subset: vertebrate_core synonym: "lachrymal bone - infraorbital 1" RELATED [VHOG:0001149] synonym: "lacrimal - infraorbital 1" RELATED [VHOG:0001149] synonym: "lacrymal bone - infraorbital 1" RELATED [VHOG:0001149] synonym: "lachrymal bone" EXACT [] synonym: "lacrymal bone" EXACT [] synonym: "lacrimal" BROAD [] synonym: "infraorbital 1" RELATED SENSU [ZFA:0000223, VHOG:0001149, TODO:TODO] xref: FMA:52741 ! Lacrimal bone xref: VHOG:0001149 ! lacrimal bone xref: MA:0001486 ! lacrimal bone xref: ncithesaurus:Lacrimal_Bone ! Lacrimal Bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: part_of UBERON:0011156 ! facial skeleton relationship: overlaps UBERON:0001697 {source="ZFA-modified"} ! orbit relationship: part_of UBERON:0003113 {source="Kardong", notes="orbital series"} ! dermatocranium relationship: dubious_for_taxon NCBITaxon:8292 {source="Wikipedia"} ! Amphibia xref: SCTID:272675007 ! Entire lacrimal bone synonym: "os lacrimale" RELATED LATIN [Wikipedia:Lacrimal_bone] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray164.png property_value: homology_notes "The infraorbital bone 1 of actinopterygians is homologous with the lacrimal bone (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001149", ontology="VHOG", source="ISBN:978-3899370805 Arratia G\, Schultze HP\, Wilson MVH\, Mesozoic Fishes 4 - Homology and Phylogeny (2008) p.23-48", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: UMLS:C0222733 [Term] id: UBERON:0001681 name: nasal bone def: "One of two small oblong bones, varying in size and form in different individuals; they are placed side by side at the middle and upper part of the face, and form, by their junction, 'the bridge' of the nose[WP]. Paired dermal bones, likened to a bone tube, positioned lateral to the supraethmoid. Nasal bones are transversed by the anterior most part of the supraorbital canals and bear one neuromast foramen in zebrafish[ZFA]." [Wikipedia:Nasal_bone, ZFIN:curator] comment: Taxon notes: In primitive bony fish and tetrapods, the nasal bones are the most anterior of a set of four paired bones forming the roof of the skull, being followed in sequence by the frontals, the parietals, and the postparietals. Their form in living species is highly variable, depending on the shape of the head, but they generally form the roof of the snout or beak, running from the nostrils to a position short of the orbits. In most animals, they are generally therefore proportionally larger than in humans or great apes, because of the shortened faces of the latter. Turtles, unusually, lack nasal bones, with the prefrontal bones of the orbit reaching all the way to the nostrils (ISBN 0-03-910284-X) subset: uberon_slim subset: vertebrate_core xref: FMA:52745 ! Nasal bone xref: GAID:222 ! nasal bone xref: VHOG:0001370 ! nasal bone xref: MA:0001494 ! nasal bone xref: TAO:0000365 ! nasal bone xref: ZFA:0000365 ! nasal bone xref: EMAPA:19202 ! nasal bone xref: AAO:0000312 ! nasal xref: ncithesaurus:Nasal_Bone ! Nasal Bone xref: OpenCyc:Mx4rwGOTZJwpEbGdrcN5Y29ycA ! nasal bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Illu_facial_bones.jpg/200px-Illu_facial_bones.jpg xref: MESH:A02.835.232.781.324.665 ! nasal bone is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0010428 {source="FMA"} ! flat bone relationship: part_of UBERON:0000004 ! olfactory apparatus relationship: part_of UBERON:0011156 ! facial skeleton relationship: in_lateral_side_of UBERON:0011156 ! facial skeleton relationship: part_of UBERON:0003113 {source="Kardong", notes="facial series"} ! dermatocranium xref: SCTID:181801008 ! Entire nasal bone synonym: "os nasale" RELATED LATIN [Wikipedia:Nasal_bone] xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg property_value: external_definition "Paired bone of intramembranous origin that roofs the olfactory capsule.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000312", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000312", date_retrieved="2012-06-20"} property_value: external_definition "Paired dermal bones, likened to a bone tube, positioned lateral to the supraethmoid. Nasal bones are transversed by the anterior most part of the supraorbital canals and bear one neuromast foramen in zebrafish Cubbage and Mabee, 1996.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000365", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps mesethmoid-nasal joint (TAO:0001677)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000365", date_retrieved="2012-08-14"} synonym: "nasals" RELATED PLURAL [TAO:0000365] synonym: "adnasal@fr" RELATED [TAO:0000365] synonym: "nasal@fr" RELATED [TAO:0000365] property_value: external_comment "Synonym adnasal used in Weitzman 1960, and synonym discussed in Vari 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000365", date_retrieved="2012-09-06", source="Curator"} relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: UMLS:C0027422 [Term] id: UBERON:0001682 name: palatine bone def: "A paired dermal bone situated in the mid-palate[Palaeos]." [Wikipedia:Palatine_bone, http://palaeos.com/vertebrates/bones/dermal/palatal-palatines.html] comment: Fusion of dermopalatine+autopalatine. subset: uberon_slim synonym: "palatum" RELATED [Wikipedia:Palatine_bone] synonym: "os palatinum" RELATED LATIN [] synonym: "palate bone" RELATED [] synonym: "palatine" EXACT [] synonym: "dermopalatine" NARROW [http://palaeos.com/vertebrates/glossary/glossaryD.html] xref: FMA:52746 ! Palatine bone xref: MA:0001495 ! palatine bone xref: ncithesaurus:Palatine_Bone ! Palatine Bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/44/Gray996.png/200px-Gray996.png xref: SCTID:244654005 ! Entire palatine bone xref: http://upload.wikimedia.org/wikipedia/commons/4/44/Gray996.png xref: TAO:0000015 ! dermopalatine xref: http://palaeos.com/vertebrates/bones/dermal/images/289x311xPalatine1.gif.pagespeed.ic.tglmNBrF4D.png is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0008907 {source="Palaeos"} ! dermal bone relationship: connected_to UBERON:0002397 ! maxilla relationship: part_of UBERON:0011156 ! facial skeleton relationship: in_lateral_side_of UBERON:0012072 {source="Kardong"} ! palatal part of dermatocranium relationship: part_of UBERON:0012072 {source="Kardong", notes="palatal series"} ! palatal part of dermatocranium relationship: part_of UBERON:0012074 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! bony part of hard palate relationship: connected_to UBERON:0001682 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="opposite"} ! palatine bone relationship: never_in_taxon NCBITaxon:32519 {source="TAO"} ! Ostariophysi relationship: develops_from UBERON:0002342 ! neural crest relationship: develops_from UBERON:0000924 ! ectoderm property_value: external_definition "Dermal bone that forms the antero-lateral region of the palate and is located ventral to the autopalatine. The dermopalatine is bilaterally paired and usually bears teeth.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000015", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: external_comment "In ostariophysans, the dermopalatine is absent.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000015", date_retrieved="2012-09-06", source="Curator"} property_value: external_comment "Dermopalatine: same as palatine. The prefix is used by fish people because the palatine is a dermal replacement bone for a section of the autopalatine section of the palatoquadrate. In that context, palatine is potentially ambiguous.[Palaeos]" xsd:string {date_retrieved="2012-09-17", source="http://palaeos.com/vertebrates/glossary/glossaryD.html"} relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: UMLS:C0222734 [Term] id: UBERON:0011634 name: ectopterygoid bone def: "a palatal bone which -- like many palatal bones -- may originally have developed as a dermal bone replacing part of the palatoquadrate, the primitive upper jaw. Like the palatine (also called dermopalatine), the ectopterygoid replaces the middle part of the autopalatine. It may be serially homologous with the palatine(s), but is somewhat specialized, being the last (most posterior in palatal view) of the series and bordering the fossa for the jaw muscles. In a typical tetrapod it abuts the palatine anteriorly, the maxilla laterally, the pterygoid or the fossa mandubuaris medially, and the fossa posteriorly" [http://palaeos.com/vertebrates/glossary/glossaryE.html] synonym: "ectopterygoid" EXACT [TAO:0000656] comment: Provenance notes: taken from TAO but is present in tetrapods is_a: UBERON:0008907 {source="TAO"} ! dermal bone relationship: part_of UBERON:0012072 {source="Kardong", notes="palatal series"} ! palatal part of dermatocranium relationship: serially_homologous_to UBERON:0001682 {source="http://palaeos.com/vertebrates/bones/dermal/palatal-palatines.html", notes="may be serially homologous with the palatines"} ! palatine bone xref: TAO:0000656 ! ectopterygoid xref: ZFA:0000656 ! ectopterygoid property_value: external_definition "Dermal bone that forms the lateral border of the palate and articulates with the quadrate posteriorly, the entopterygoid medially and the dermopalatine and/or autopalatine antero-laterally. The ectopterygoid is a paired bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000656", date_retrieved="2012-08-14", source="TAO:ga_tg", source="ZFIN:curator"} property_value: external_comment "The ectopterygoid is often toothed.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000656", date_retrieved="2012-09-06", source="Curator"} xref: EFO:0003552 ! ectopterygoid [Term] id: UBERON:0004867 name: orbital cavity comment: AO notes: note that the AAO class is a cavity synonym: "orbit" RELATED [AAO:0000343] intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: part_of UBERON:0001697 ! orbit xref: FMA:84961 ! orbital cavity xref: SCTID:280541000 ! Orbital cavity xref: AAO:0000343 ! orbit def: "An anatomical cavity that is part of a orbital region." [OBOL:automatic] [Term] id: UBERON:0001697 ! orbital region name: orbital region def: "Anatomical cluster that is a anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball." [TAO:0001410, Wikipedia:Orbit_(anatomy)] comment: AO notes: in FMA, this overlaps with bones such as the maxilla and sphenoid; in ZFA, individual bones are part of the orbit subset: uberon_slim subset: vertebrate_core synonym: "orbit of skull" EXACT [FMA:53074] synonym: "eye socket" EXACT [] synonym: "bony orbit" EXACT [] synonym: "orbit" RELATED [ZFA:0001410] xref: FMA:53074 ! Orbit xref: GAID:223 ! orbit xref: MA:0002482 ! orbit xref: ncithesaurus:Orbit xref: OpenCyc:Mx4rvW8EgZwpEbGdrcN5Y29ycA xref: XAO:0003171 ! orbital region xref: ZFA:0001410 ! orbital region xref: galen:Orbit ! orbit xref: BTO:0004687 ! orbit xref: MESH:A02.835.232.781.324.690 ! orbit is_a: UBERON:0000477 {source="ZFA"} ! anatomical cluster relationship: part_of UBERON:0011156 ! facial skeleton relationship: encloses UBERON:0000019 ! camera-type eye xref: TAO:0001410 ! orbital region property_value: external_definition "Anatomical cluster that is a anterolateral part of the cranium and structurally supports the eye.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001410", date_retrieved="2012-08-14", source="TAO:MAH"} relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: UMLS:C0029180 [Term] id: UBERON:0001683 name: jugal bone def: "The zygomatic bone is a paired dermal bone which articulates with the maxilla. In humans it also articulates with the temporal bone, the sphenoid bone and the frontal bone. The zygomatic is homologous to the jugal bone of other tetrapods. It is situated at the upper and lateral part of the face and forms the prominence of the cheek, part of the lateral wall and floor of the orbit, and parts of the temporal and infratemporal fossae. It presents a malar and a temporal surface; four processes, the frontosphenoidal, orbital, maxillary, and temporal; and four borders[WP,modified]." [Wikipedia:Zygomatic_bone, Wikipedia:Jugal_bone] comment: Taxon notes: vHOG says is homologous to infraorbital 3. subset: uberon_slim synonym: "cheek bone" EXACT [] synonym: "orbital bone" EXACT [] synonym: "zygomatic" RELATED [] synonym: "jugale" RELATED SENSU [] synonym: "jugal bone" RELATED [GAID:225, Wikipedia:Zygomatic_bone] synonym: "jugal" RELATED [Wikipedia:Zygomatic_bone] synonym: "zygoma" RELATED [GAID:225] synonym: "os zygomaticum" EXACT [FMA:52747, FMA:TA] synonym: "os zygomaticus" RELATED [Wikipedia:Zygomatic_bone] synonym: "malar bone" EXACT [FMA:52747] synonym: "zygomatic bone" EXACT [MA:0001497] xref: FMA:52747 ! Zygomatic bone xref: MA:0001497 ! zygomatic bone xref: GAID:225 ! zygoma xref: VHOG:0001638 ! zygomatic bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Gray164.png/200px-Gray164.png xref: EMAPA:25111 ! zygomatic bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: part_of UBERON:0001567 ! cheek relationship: part_of UBERON:0003113 {source="Kardong", notes="orbital series"} ! dermatocranium relationship: part_of UBERON:0011156 ! facial skeleton relationship: in_lateral_side_of UBERON:0011156 ! facial skeleton relationship: overlaps UBERON:0001697 {source="Kardong"} ! orbital region xref: SCTID:272683001 ! Entire os zygomaticum synonym: "os zygomaticum" RELATED LATIN [Wikipedia:Zygomatic_bone] synonym: "zygoma" RELATED [Wikipedia:Zygomatic_bone] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray164.png property_value: homology_notes " (...) and the infraorbital bone 3 of advanced actinopterygians (is homologous) with the jugal bone of sarcopterygians.[well established][VHOG]" xsd:string {external_class="VHOG:0001638", ontology="VHOG", source="ISBN:978-3899370805 Arratia G\, Schultze HP\, Wilson MVH\, Mesozoic Fishes 4 - Homology and Phylogeny (2008) p.23-48", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton property_value: external_definition "The jugal is a skull bone found in most reptiles, amphibians, and birds. In mammals, the jugal is often called the malar or Zygomatic. It is connected to the quadratojugal and maxilla, as well as other bones, which may vary by species. This bone is considered key in the determination of general traits of the skull, in the case of creatures, as with dinosaurs in paleontology, whose entire skull has not been found[Wikipedia:Jugal_bone]." xsd:string {source="Wikipedia:Jugal_bone"} property_value: external_definition "The zygomatic bone is a paired dermal bone which articulates with the maxilla. In humans it also articulates with the temporal bone, the sphenoid bone and the frontal bone. The zygomatic is homologous to the jugal bone of other tetrapods. It is situated at the upper and lateral part of the face and forms the prominence of the cheek, part of the lateral wall and floor of the orbit, and parts of the temporal and infratemporal fossae. It presents a malar and a temporal surface; four processes, the frontosphenoidal, orbital, maxillary, and temporal; and four borders[WP,modified][Wikipedia:Zygomatic_bone]." xsd:string {source="Wikipedia:Zygomatic_bone"} [Term] id: UBERON:0002500 name: zygomatic arch def: "The zygomatic arch or cheek bone is formed by the zygomatic process of temporal bone (a bone extending forward from the side of the skull, over the opening of the ear) and the temporal process of the zygomatic bone (the side of the cheekbone), the two being united by an oblique suture; the tendon of the Temporalis passes medial to the arch to gain insertion into the coronoid process of the mandible. The term zygomatic derives from the Latin zyosislymore meaning malar bone or cheekbone. The zygomatic arch is occasionally referred to as the zygoma, but this term usually refers to the zygomatic bone or occasionally the zygomatic process. The zygomatic process of the temporal arises by two roots: an anterior, directed inward in front of the mandibular fossa, where it expands to form the articular tubercle. a posterior, which runs backward above the external acoustic meatus and is continuous with the supramastoid crest. The upper border of the arch gives attachment to the temporal fascia; the lower border and medial surface give origin to the Masseter. The zygomatic arch is significant in evolutionary biology, as it is part of the structures derived from the ancestral single temporal fenestra of the synapsid ancestor of mammals. [WP,unvetted]." [Wikipedia:Zygomatic_arch] comment: Editors note: compare with zygomatic bone subset: uberon_slim synonym: "zygoma" EXACT [] xref: FMA:53120 ! Zygomatic arch xref: MA:0002810 ! zygomatic arch xref: ncithesaurus:Zygomatic_Arch ! Zygomatic Arch xref: galen:Zygoma ! zygoma xref: OpenCyc:Mx4rvih1YZwpEbGdrcN5Y29ycA ! zygoma xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f4/Gray188-Sphenozygomatic_suture.png/200px-Gray188-Sphenozygomatic_suture.png xref: MESH:A02.835.232.781.324.995 ! zygoma is_a: UBERON:0011164 {source="MA"} ! neurocranium bone xref: SCTID:272682006 ! Entire zygomatic arch synonym: "arcus zygomaticus" RELATED LATIN [Wikipedia:Zygomatic_arch] xref: http://upload.wikimedia.org/wikipedia/commons/f/f4/Gray188-Sphenozygomatic_suture.png relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: UMLS:C0162485 [Term] id: UBERON:0012108 name: postorbital bar def: "A strut formed from the union of the zygomatic process of the frontal bone with the frontal process of the zygomatic bone." [Wikipedia:Postorbital_Bar, MURDOCH:1580] synonym: "post-orbital bar" EXACT [] is_a: UBERON:0005913 ! zone of bone organ relationship: has_fused_element UBERON:0012110 ! frontal process of zygomatic bone relationship: has_fused_element UBERON:0012109 ! zygomatic process of frontal bone relationship: part_of UBERON:0003113 {notes="orbital series"} ! dermatocranium relationship: only_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: UBERON:0012109 name: zygomatic process of frontal bone def: "The part of the zygomatic process consisting of the frontal bone[WP]" [Wikipedia:Zygomatic_process_of_frontal_bone] synonym: "frontal bone - zygomatic process" EXACT [] synonym: "processus zygomaticus (os frontale)" EXACT [FMA:54389] synonym: "processus zygomaticus ossis frontalis" EXACT LATIN [Wikipedia:Zygomatic_process_of_frontal_bone] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0000209 ! tetrapod frontal bone relationship: connected_to UBERON:0001683 ! zygomatic bone xref: FMA:54389 ! zygomatic process of frontal bone xref: SCTID:427577001 ! Entire zygomatic process of frontal bone [Term] id: UBERON:0012110 name: frontal process of zygomatic bone synonym: "zygomatic bone - frontal process" EXACT [] synonym: "processus frontalis (os zygomaticum)" EXACT [FMA:52907] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001683 ! zygomatic bone relationship: connected_to UBERON:0000209 ! tetrapod frontal bone xref: FMA:52907 ! frontal process of zygomatic bone xref: SCTID:116353002 ! Frontal process of zygomatic bone disjoint_from: UBERON:0012109 ! zygomatic process of frontal bone [Term] id: UBERON:0011267 name: quadratojugal bone def: "The quadratojugal is a small jaw bone that is present in most amphibians, reptiles, and birds, but has been lost in mammals. It is connected to the jugal as well as other bones, though these may vary with species. The quadratojugal bone is a small bone between the cheek and otic notch (Lecointre 380). Squamates (lizards and snakes) lack a quadratojugal bone (Schwenk 193)." [Wikipedia:Quadratojugal_bone] synonym: "quadratjochbeine" RELATED [AAO:0000532] synonym: "quadrato-jugals" RELATED [AAO:0000532] synonym: "quadrato-maxillare" RELATED [AAO:0000532] synonym: "quadratojugale" RELATED [AAO:0000532] synonym: "tympano maleaux" RELATED [AAO:0000532] synonym: "quadratojugal" EXACT [AAO:0000532] is_a: UBERON:0002514 {source="AAO-def"} ! intramembranous bone relationship: part_of UBERON:0003277 {source="AAO"} ! skeleton of upper jaw relationship: part_of UBERON:0003113 {source="Kardong", notes="temporal series"} ! dermatocranium relationship: never_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: never_in_taxon NCBITaxon:8509 {source="Wikipedia"} ! Squamata xref: AAO:0000532 ! quadratojugal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Archaeopteryx_skull.png/800px-Archaeopteryx_skull.png xref: http://upload.wikimedia.org/wikipedia/commons/e/eb/Skull_synapsida_1.png property_value: external_definition "Paired intramembranous bones that completes the maxillary arch posteriorly; they appear at the end of, or just after, metamorphosis[AAO:0000532]." xsd:string {source="AAO:0000532"} [Term] id: UBERON:0010272 ! hyoid apparatus name: hyoid apparatus def: "A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage" [http://www.biology-online.org/dictionary/Hyoid_apparatus] comment: Taxon notes: In most mammals, including humans, the hyoid apparatus is shaped like a horseshoe. However, in humans, some of the bones of the hyoid apparatus are fused into a single bone called os hyoideum. In other animals such as frogs, the hyoid apparatus has a hyoid body that is chiefly comprised of hyaline cartilage and two pairs of processes (i.e. alary process and the posteriolateral process). is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0005884 {source="AAO"} ! hyoid arch skeleton synonym: "apparatus hyoideus" RELATED [http://www.biology-online.org/dictionary/Hyoid_apparatus] synonym: "hyobranchial apparatus" RELATED [AAO:0000225] synonym: "apparatus hyobranchialis" RELATED LATIN [] synonym: "hyolingual system" RELATED [AAO:0000225] xref: AAO:0000225 ! hyoid apparatus xref: AAO:0000682 ! hyoid apparatus skeleton property_value: external_definition "Apparatus located in the floor of the mouth, under the mandibular arcade. The apparatus consists of a central corpus and four pairs of processes. This apparatus serves as the site of insertion for a variety of muscles associated with movements of the tongue and as the origin of the m. hyoglossus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000225", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of hyolaryngeal complex (AAO:0000226)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000225", date_retrieved="2012-06-20"} xref: SCTID:410035009 ! Entire hyoid apparatus xref: http://palaeos.com/vertebrates/bones/gill_arches/images/ReptileHyoids.gif [Term] id: UBERON:0001685 name: hyoid bone def: "The hyoid bone (lingual bone) (Latin os hyoideum) is a horseshoe shaped bone situated in the anterior midline of the neck between the chin and the thyroid cartilage. At rest, it lies at the level of the base of the mandible in the front and the third cervical vertebra behind. It is the only bone in the human skeleton not articulated to any other bone. It is held in place by thyroid ligaments. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. Its name is derived from the Greek word hyoeides meaning 'shaped like the letter upsilon' (υ). [WP,unvetted]." [Wikipedia:Hyoid_bone, Wikipedia:Hyoid_bone] comment: Taxon notes: The hyoid bone is derived from the lower half of the second gill arch in fish, which separates the first gill slit from the spiracle. In many animals, it also incorporates elements of other gill arches, and has a correspondingly greater number of cornua. Amphibians and reptiles may have many cornua, while mammals (including humans) have two pairs, and birds only one. In birds, and some reptiles, the body of the hyoid is greatly extended forward, creating a solid bony support for the tongue. The howler monkey Alouatta has a pneumatized hyoid bone, one of the few cases of postcranial pneumatization of bones outside Saurischia.[WP] synonym: "hyoid" RELATED [Wikipedia:Hyoid_bone] synonym: "hyoid bone" RELATED [Wikipedia:Hyoid_bone] synonym: "hyoideum" RELATED [Wikipedia:Hyoid_bone] synonym: "lingual bone" RELATED [Wikipedia:Hyoid_bone] synonym: "os hyoideum" RELATED [Wikipedia:Hyoid_bone] subset: uberon_slim xref: AAO:0000684 ! hyoid_bone xref: FMA:52749 ! Hyoid bone xref: GAID:197 ! hyoid bone xref: MA:0001484 ! hyoid bone xref: ncithesaurus:Hyoid_Bone ! Hyoid Bone xref: VHOG:0001325 ! hyoid bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Gray186.png/200px-Gray186.png xref: EMAPA:18650 ! hyoid bone of skeleton of pharynx of foregut xref: EMAPA:18840 ! hyoid bone of skeleton of pharynx of gut xref: MESH:A02.835.232.409 ! hyoid bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: part_of UBERON:0008895 ! splanchnocranium relationship: part_of UBERON:0010272 ! hyoid apparatus relationship: has_developmental_contribution_from UBERON:0003114 {source="Wikipedia"} ! pharyngeal arch 3 relationship: has_developmental_contribution_from UBERON:0003066 {source="Wikipedia"} ! pharyngeal arch 2 xref: SCTID:263352000 ! Entire hyoid bone synonym: "os hyoideum" RELATED LATIN [Wikipedia:Hyoid_bone] xref: http://upload.wikimedia.org/wikipedia/commons/1/1f/Gray186.png property_value: external_definition "Paired processes that extend posterolaterally from the posterior margin of the hyoid plate. These processes are the ossified posteromedial processes and invest the laryngeal apparatus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000684", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of hyoid plate (AAO:0000664)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000684", date_retrieved="2012-06-20"} xref: UMLS:C0020417 [Term] id: UBERON:0011608 ! hyomandibular element name: hyomandibular element def: "the upper paired deep bone or cartilage of the hyoid region, sometimes taking part in jaw suspension and which supports the opercle. Dorsally it articulates with the otic capsule at the hyomandibular fossa, ventrally with the quadrate and symplectic. In most Teleostei it has a foramen for the hyomandibular branch of the facial nerve (VII)." [http://en.academic.ru/dic.nsf/en_ichthyology/8715/hyomandibula] synonym: "epihyal" RELATED INCONSISTENT [http://palaeos.com/vertebrates/bones/gill_arches/gill_arches.html] synonym: "hyomandibula element" EXACT [] is_a: UBERON:0010522 ! replacement element relationship: part_of UBERON:0011152 ! dorsal hyoid arch skeleton xref: TAO:0000672 ! hyomandibula (also: UBERON:0011606 'hyomandibular bone') xref: VHOG:0000688 ! hyomandibula - stapes (also: UBERON:0011607 'hyomandibular cartilage') (also: UBERON:0011606 'hyomandibular bone') (also: UBERON:0001687 'stapes') property_value: external_definition "Replacement bone that is bilaterally paired and articulates with the neurocranium dorsally and the opercle posteriorly.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps quadrate-hyomandibula joint (TAO:0001801)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps hyomandibular-otic region joint (TAO:0001947)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps hyomandibula-metapterygoid joint (TAO:0001979)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps hyomandibula-opercle joint (TAO:0005265)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps preopercle vertical limb-hyomandibula joint (TAO:0005278)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} synonym: "hyomandibula - stapes" EXACT [VHOG:0000688] property_value: external_comment "In most teleosts, there is a symplectic, and the hyomandibula articulates with it anteroventrally.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-09-06", source="Curator"} property_value: homology_notes "This structure (the hyomandibular), on ontogenic grounds alone, can be considered homologous with the amphibian and reptilian columella and the mammalian stapes.[well established][VHOG]" xsd:string {external_class="VHOG:0000688", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0011607 ! hyomandibular cartilage name: hyomandibular cartilage def: "Cartilage form of the hyomandibular element." [UBERON:cjm] comment: Taxon notes: The stapes is homologous to the hyomandibula. In this ontology, we use the class 'hyomandibular cartilage' generally to include the future stapes, the future hyomandibular bone of teleosts and the unossified cartilage in sharks. synonym: "hyosymplectic cartilage" EXACT [ZFA:0001422] synonym: "symplectic cartilage" EXACT [TAO:0001422] is_a: UBERON:0011004 {source="TAO"} ! pharyngeal arch cartilage is_a: UBERON:0011608 ! hyomandibular element xref: TAO:0001422 ! hyosymplectic cartilage xref: ZFA:0001422 ! hyosymplectic cartilage xref: VHOG:0000688 ! hyomandibula - stapes (also: UBERON:0011608 'hyomandibular element') (also: UBERON:0011606 'hyomandibular bone') (also: UBERON:0001687 'stapes') property_value: external_definition "Pharyngeal arch cartilage that is bilaterally paired and articulates with the chondrocranium dorsally, the opercle bone posteriorly, and the palatoquadrate cartilage anteriorly.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001422", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "This structure (the hyomandibular), on ontogenic grounds alone, can be considered homologous with the amphibian and reptilian columella and the mammalian stapes.[well established][VHOG]" xsd:string {external_class="VHOG:0000688", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: EFO:0003686 ! hyosymplectic cartilage [Term] id: UBERON:0011606 ! hyomandibular bone name: hyomandibular bone def: "Replacement bone that is bilaterally paired and (in teleosts) articulates with the neurocranium dorsally and the opercle posteriorly[TAO,modified]." [TAO:0000672, Wikipedia:Hyomandibula] comment: In most teleosts, there is a symplectic, and the hyomandibula articulates with it anteroventrally. synonym: "hyomandibular" BROAD [TAO:0000672, Wikipedia:Hyomandibula] synonym: "hyomandibula" BROAD [TAO:0000672] xref: VHOG:0000688 ! hyomandibula - stapes (also: UBERON:0011608 'hyomandibular element') (also: UBERON:0011607 'hyomandibular cartilage') (also: UBERON:0001687 'stapes') is_a: UBERON:0002513 {source="TAO"} ! endochondral bone is_a: UBERON:0011608 ! hyomandibular element relationship: develops_from UBERON:0011607 {source="TAO"} ! hyomandibular cartilage xref: TAO:0000672 ! hyomandibula (also: UBERON:0011608 'hyomandibular element') xref: ZFA:0000672 ! hyomandibula property_value: external_definition "Replacement bone that is bilaterally paired and articulates with the neurocranium dorsally and the opercle posteriorly.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps quadrate-hyomandibula joint (TAO:0001801)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps hyomandibular-otic region joint (TAO:0001947)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps hyomandibula-metapterygoid joint (TAO:0001979)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps hyomandibula-opercle joint (TAO:0005265)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps preopercle vertical limb-hyomandibula joint (TAO:0005278)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000672", date_retrieved="2012-08-14"} property_value: homology_notes "This structure (the hyomandibular), on ontogenic grounds alone, can be considered homologous with the amphibian and reptilian columella and the mammalian stapes.[well established][VHOG]" xsd:string {external_class="VHOG:0000688", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: EFO:0003556 ! hyomandibula [Term] id: UBERON:0011609 ! ceratohyal element name: ceratohyal element synonym: "keratohyal element" RELATED [] is_a: UBERON:0010522 ! replacement element relationship: part_of UBERON:0011153 {source="TAO-abduced"} ! ventral hyoid arch skeleton [Term] id: UBERON:0011610 name: ceratohyal cartilage is_a: UBERON:0011609 ! ceratohyal element is_a: UBERON:0011004 {source="TAO"} ! pharyngeal arch cartilage xref: TAO:0001400 ! ceratohyal cartilage xref: ZFA:0001400 ! ceratohyal cartilage property_value: external_definition "Pharyngeal arch cartilage that is bilaterally paired and the largest cartilaginous component of the ventral hyoid arch.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001400", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps interhyal-epihyal joint (TAO:0001841)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001400", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps inter-ventral hypohyal joint (TAO:0001846)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001400", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps dorsal hypohyal-urohyal joint (TAO:0001847)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001400", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps ventral hypohyal-urohyal joint (TAO:0001848)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001400", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps epihyal-branchiostegal ray joint (TAO:0001849)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001400", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps ceratohyal-branchiostegal ray joint (TAO:0001850)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001400", date_retrieved="2012-08-14"} [Term] id: UBERON:0011611 name: ceratohyal bone synonym: "ceratohyale" RELATED [AAO:0000666] synonym: "hyale" RELATED [AAO:0000666] synonym: "hyoid" RELATED [AAO:0000666] synonym: "keratohyale" RELATED [AAO:0000666] synonym: "zungenbeinknorpel" RELATED [AAO:0000666] synonym: "anterohyal" EXACT [TAO:0000578] synonym: "ceratohyal" EXACT [TAO:0000578] synonym: "ceratohyal anterior" EXACT [TAO:0000578] synonym: "ceratohyal bone" EXACT [TAO:0000578] synonym: "distal ceratohyal" EXACT [TAO:0000578] synonym: "rostral ceratohyal" EXACT [TAO:0000578] synonym: "anterior ceratohyal" EXACT [TAO:0000578] synonym: "ceratohyoid bone" EXACT [] synonym: "ceratohyoid" NARROW SENSU [] is_a: UBERON:0011609 ! ceratohyal element is_a: UBERON:0002513 {source="TAO"} ! endochondral bone relationship: develops_from UBERON:0011610 {source="TAO"} ! ceratohyal cartilage relationship: homologous_to UBERON:0003998 ! hyoid bone lesser horn xref: AAO:0000666 ! ceratohyal xref: TAO:0000578 ! anterior ceratohyal xref: ZFA:0000578 ! ceratohyal bone xref: SCTID:370641002 ! Ceratohyoid bone property_value: external_definition "Replacement bone that is bilaterally paired and articulates with the hypohyal cartilage or bone, dorsal and ventral hypohyals, and posterior ceratohyal posteriorly.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000578", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps epihyal-ceratohyal joint (TAO:0001842)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000578", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps ceratohyal-dorsal hypohyal joint (TAO:0001843)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000578", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps ceratohyal-ventral hypohyal joint (TAO:0001844)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000578", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps ceratohyal-branchiostegal ray joint (TAO:0001850)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000578", date_retrieved="2012-08-14"} synonym: "anterohyals" RELATED PLURAL [TAO:0000578] synonym: "ceratohyals" RELATED PLURAL [TAO:0000578] [Term] id: UBERON:0011613 ! hypohyal element name: hypohyal element def: "The hypohyal is a ventral element of the hyoid arch which links the ceratohyal and the basihyal." [http://palaeos.com/vertebrates/bones/gill_arches/hypohyal.html] is_a: UBERON:0010522 ! replacement element relationship: part_of UBERON:0011153 {source="TAO-abduced"} ! ventral hyoid arch skeleton [Term] id: UBERON:0011612 name: hypohyal cartilage is_a: UBERON:0011004 {source="TAO"} ! pharyngeal arch cartilage is_a: UBERON:0011613 ! hypohyal element xref: TAO:0001868 ! hypohyal cartilage property_value: external_definition "Pharyngeal arch cartilage that is bilaterally paired and articulates posteriorly with the ceratohyal cartilage.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001868", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0004751 name: hypohyal bone synonym: "hypohyals" EXACT PLURAL [ZFA:0001381] xref: AAO:0000958 ! hypohyal xref: ZFA:0001381 ! hypohyal bone xref: TAO:0001381 ! hypohyal bone is_a: UBERON:0002513 {source="TAO"} ! endochondral bone is_a: UBERON:0011613 ! hypohyal element relationship: part_of UBERON:0010272 {source="AAO"} ! hyoid apparatus relationship: part_of UBERON:0011153 {source="TAO"} ! ventral hyoid arch skeleton relationship: develops_from UBERON:0011610 {source="TAO"} ! ceratohyal cartilage relationship: develops_from UBERON:0011612 {source="TAO"} ! hypohyal cartilage property_value: external_definition "Paired element that articulates anterioly with the basihyal and posteriorly with the ceratohyal hypohyals.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000958", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of hyoid apparatus skeleton (AAO:0000682)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000958", date_retrieved="2012-06-20"} property_value: external_definition "Replacement bone that is bilaterally paired and articulates with the anterior ceratohyal posteriorly.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001381", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0011614 name: basihyal element def: "Skeletal element that is median and is the anterior-most element of the ventral hyoid arch." [TAO:0001891] is_a: UBERON:0010522 ! replacement element relationship: part_of UBERON:0011153 {source="TAO"} ! ventral hyoid arch skeleton xref: TAO:0001891 ! basihyal element [Term] id: UBERON:0011615 name: basihyal cartilage def: "Pharyngeal arch cartilage that is median and is the anterior-most cartilage of the ventral hyoid arch." [TAO:0001510] synonym: "copula 1" EXACT [TAO:0001510] is_a: UBERON:0011004 {source="TAO"} ! pharyngeal arch cartilage is_a: UBERON:0011614 {source="TAO"} ! basihyal element xref: TAO:0001510 ! basihyal cartilage xref: ZFA:0001510 ! basihyal cartilage [Term] id: UBERON:0011618 ! basihyal bone name: basihyal bone def: "Replacement bone that is median and is the anterior-most bone of the ventral hyoid arch." [TAO:0000316] synonym: "basihyoid" EXACT [TAO:0000316] synonym: "glossohyal" EXACT [TAO:0000316] is_a: UBERON:0002513 {source="TAO"} ! endochondral bone is_a: UBERON:0011614 {source="TAO"} ! basihyal element relationship: develops_from UBERON:0011615 {source="TAO"} ! basihyal cartilage relationship: homologous_to UBERON:0003999 ! hyoid bone body xref: VSAO_RETIRED:0000007 ! basihyal bone xref: ZFA:0000316 ! basihyal bone xref: TAO:0000316 ! basihyal bone [Term] id: UBERON:0011619 name: stylohyoid bone def: "This is the paired bone that makes up the segment of the mammalian hyoid apparatus connecting the epihyoids with the skull via the tympanohyoid cartilages on each side. Ventrally, it defines the medial and lateral compartments of the guttural pouch in the horse." [MURDOCH:1758] comment: Taxon notes: The stylohyoid bone is one of the four bones ( stylohyoid, ceratohyoid, basihyoid, thyrohyoid) of the hyoid apparatus in the horse. Other species have five bones, the fifth being the epihyoid that is not present in the horse. The stylohyoid bone in the horse is significantly larger compared to other bones of the hyoid apparatus and divides the guttural pouch into two chambers, medial and lateral. The hyoid apparatus consists of a series of bony rods, jointed together and forming a means of suspending the tongue and larynx from the skull[MURDOCH] is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0010272 ! hyoid apparatus xref: SCTID:370715004 ! Stylohyoid bone [Term] id: UBERON:0011620 name: basihyal lingual process def: "A projection on the basihyal bone. Laterally the lingual process is compressed. It has a blunt pointed free end, and its lateral surfaces are slightly concave. The dorsal border is thin and irregular, and the ventral border is thick and rough. In the living animal the lingual process is embedded within the root of the tongue." [MURDOCH:1080] synonym: "lingual process of basihyoid bone" EXACT [] synonym: "lingual process of hyoid" RELATED [] synonym: "lingual process of basihyoid" EXACT [] is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0011618 ! basihyal bone [Term] id: UBERON:0011621 name: thyrohyoid cartilage def: "This small finger of cartilage completes the connection between the thyrohyoid bone and the thyroid cartilage (rostral cornu)" [MURDOCH:2033] is_a: UBERON:0011004 {source="TAO"} ! pharyngeal arch cartilage relationship: part_of UBERON:0010272 ! hyoid apparatus relationship: connects UBERON:0011622 ! thyrohyoid bone relationship: connects UBERON:0011623 ! horn of thyroid cartilage [Term] id: UBERON:0011622 ! thyrohyoid bone name: thyrohyoid bone def: "Is a laterally bowed, sagitally compressed, slender element that extends from dorsocaudally from the lateral parts of the basihyoid. It connects the basiohyoid with the rostral corner of the thyroid cartlilage of the larynx." [MURDOCH:1951] is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0010272 ! hyoid apparatus relationship: connects UBERON:0011618 ! basihyal bone relationship: connects UBERON:0011623 ! horn of thyroid cartilage xref: SCTID:370708007 ! Thyrohyoid bone [Term] id: UBERON:0011626 name: tympanohyoid cartilage def: "the terminal segment in the chain of skeletal elements of the hyoid apparatus. One of a pair of rods of cartilage that connect the hyoid bone to the styloid process of the petrous part of the temporal bone" [http://medical-dictionary.thefreedictionary.com/tympanohyoid] is_a: UBERON:0011004 ! pharyngeal arch cartilage relationship: part_of UBERON:0010272 ! hyoid apparatus relationship: connects UBERON:0001685 ! hyoid bone relationship: connects UBERON:0003960 ! styloid process of temporal bone xref: SCTID:370702008 ! Tympanohyoid cartilage [Term] id: UBERON:0001686 name: auditory ossicle def: "One of 3 small bones contained within the middle ear space and serve to transmit sounds from the air to the fluid-filled labyrinth. The absence of the auditory ossicles would constitute a moderate-to-severe hearing loss. The term 'ossicles' literally means 'tiny bones' and commonly refers to the auditory ossicles, though the term may refer to any small bone throughout the body. [WP,unvetted]." [Wikipedia:Auditory_ossicle] comment: Taxon and editor notes: This should probably be restricted to mammals - the AAO/XAO structures may group non-homologous structures [Wikipedia:Evolution_of_mammalian_auditory_ossicles] see https://github.com/seger/aao/issues/5. Development notes: Studies have shown that ear bones in mammal embryos are attached to the dentary, which is part of the jaw. These are ossified portions of cartilage -- called Meckel's cartilage -- that are attached to the jaw. As the embryo develops, the cartilage hardens to form bone. Later in development, the bone structure breaks loose from the jaw and migrates to the inner ear area. The structure is known as the middle ear, and is made up of the incus, stapes, malleus, and tympanic membrane. These correspond to the quadrate, prearticular, articular, and angular structures in the reptile jaw. For this reason, researchers believe the similarity of the results shows that mammals and reptiles have a common ancestry.[WP] subset: uberon_slim synonym: "auditory ossicle" RELATED [MA:0000254] synonym: "ear bone" RELATED [MA:0000254] synonym: "ear ossicle" RELATED [] synonym: "ear ossicles" RELATED PLURAL [] synonym: "ossicular chain" RELATED PLURAL [] synonym: "ossicle of ear" RELATED [] synonym: "ossicle of inner ear" RELATED [] synonym: "middle ear bone" RELATED [] synonym: "auditory bone" EXACT [] synonym: "middle ear ossicle" EXACT [MP:0005105] synonym: "ossicle" BROAD [EMAPA:17824, Wikipedia:Auditory_ossicle] xref: EHDAA:5697 ! ossicle xref: EMAPA:17824 ! ossicle xref: FMA:52750 ! Auditory ossicle xref: VHOG:0000461 ! auditory ossicle xref: MA:0000254 ! auditory bone xref: XAO:0000214 ! auditory ossicle xref: ncithesaurus:Auditory_Ossicle ! Auditory Ossicle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b0/Illu_auditory_ossicles.jpg/200px-Illu_auditory_ossicles.jpg xref: EHDAA2:0001183 ! middle ear ossicle xref: EV:0100360 ! auditory ossicle xref: SCTID:181184001 ! Entire ossicle of ear is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: part_of UBERON:0001756 {source="MA"} ! middle ear relationship: part_of UBERON:0008895 {source="PMID:11523816"} ! splanchnocranium relationship: develops_from UBERON:0003099 {source="PMID:11237469", source="UBERONREF:0000002"} ! cranial neural crest xref: AAO:0011015 ! auditory ossicle property_value: external_definition "The small bones of the middle ear: incus, malleus, and stapes. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000461", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/auditory+ossicles", source="http://bgee.unil.ch/"} property_value: homology_notes "Additional structural analysis within a phylogenetic context has led to the remarkable discovery that in synapsids, thought to be ancestral to mammals, both the quadrate and articular have become reduced and less firmly articulated with their surrounding bones, reducing their jaw-joint-bearing role. This trend culminated with the incorporation of the quadrate, the columella (which remains articulated with the quadrate), and the articular into the expanded middle ear in mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0000461", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.695", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0013450 [Term] id: UBERON:0001687 name: stapes def: "The stapes or stirrup is the stirrup-shaped small bone or ossicle in the middle ear which is attached to the incus laterally and to the fenestra ovalis, the 'oval window' medially. The oval window is adjacent to the vestibule of the inner ear. The stapes is the smallest and lightest bone in the human body. The stapes transmits the sound vibrations from the incus to the membrane of the inner ear inside the fenestra ovalis. The stapes is also stabilized by the stapedius muscle, which is innervated by the facial nerve. In non-mammalian vertebrates, the bone homologous to the stapes is usually called the columella; however, in reptiles, either term may be used[WP,unvetted]." [Wikipedia:Stapes, doi:10.1111/j.1469-7580.2005.00441.x] comment: Editor notes: Consider adding classes for homologs; we do not include a class for hyomandibula in uberon, no need to generalize the TAO/ZFA class. Taxon notes (via VHOG): "This structure [the hyomandibular], on ontogenic grounds alone, can be considered homologous with the amphibian and reptilian columella and the mammalian stapes." Gerrie J, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948) 62:339-357? Development notes: As the stapes first develops embryologically from the 6th to 8th week of life, it surrounds the stapedial artery, which supplies the majority of the vasculature of the embryonic head. After that period, the external carotid artery is generated and takes over for the stapedial artery, which subsequently involutes, leaving the stapes with a windowframe-like structure[WP] The stapes develops at the cranial end of the second branchial arch through an independent anlage of the cartilage of this arch. Between the stapedial anlage and the cranial end of the Reichert's cartilage there is a formation called the interhyale, the internal segment of which gives rise to the tendon of the stapedial muscle. The stapedial anlage is a unique formation with two distinct parts: the superior part that will comprise the base and the inferior part that will be crossed by the stapedial artery during embryonic development and will constitute the limbs and the head of the stapes. According to the results, the otic capsule is not involved in formation of the base of the stapes.[doi:10.1111/j.1469-7580.2005.00441.x] subset: uberon_slim synonym: "stirrup" EXACT [] synonym: "columella" RELATED SENSU [Wikipedia:Stapes] synonym: "columella auris" RELATED [AAO:0000580] synonym: "columellare" RELATED [AAO:0000580] synonym: "interstapediale" RELATED [AAO:0000580] synonym: "mediostapediale" RELATED [AAO:0000580] synonym: "mesostapediale" RELATED [AAO:0000580] synonym: "os columellare" RELATED [AAO:0000580] synonym: "os intermedium" RELATED [AAO:0000580] synonym: "stapes" RELATED [AAO:0000580] synonym: "stelidium" RELATED [AAO:0000580] synonym: "stilus columellare" RELATED [AAO:0000580] xref: FMA:52751 ! Stapes xref: GAID:868 ! stape xref: MA:0001217 ! stapes xref: OpenCyc:Mx4rv5UnkZwpEbGdrcN5Y29ycA xref: ncithesaurus:Stapes ! Stapes xref: OpenCyc:Mx4rv5UnkZwpEbGdrcN5Y29ycA ! stapes xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c1/Gray918.png/200px-Gray918.png xref: EMAPA:18585 ! stapes xref: MESH:A09.246.397.247.806 ! stape is_a: UBERON:0001686 ! auditory ossicle xref: SCTID:264199009 ! Entire stapes xref: VHOG:0000688 ! hyomandibula - stapes (also: UBERON:0011608 'hyomandibular element') (also: UBERON:0011607 'hyomandibular cartilage') (also: UBERON:0011606 'hyomandibular bone') relationship: homologous_to UBERON:0011606 {source="VHOG"} ! hyomandibula relationship: homologous_to AAO:0000580 {source="Wikipedia:Stapes"} ! stylus of pars media plectri relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: develops_from UBERON:0010055 {source="definitional"} ! stapes cartilage condensation relationship: develops_from UBERON:0004368 {source="classical definition", contradicted_by="doi:10.1111/j.1469-7580.2006.00524.x"} ! Reichert's cartilage synonym: "stapellos" RELATED LATIN [Wikipedia:Stapes] xref: http://upload.wikimedia.org/wikipedia/commons/c/c1/Gray918.png property_value: homology_notes "This structure (the hyomandibular), on ontogenic grounds alone, can be considered homologous with the amphibian and reptilian columella and the mammalian stapes.[well established][VHOG]" xsd:string {external_class="VHOG:0000688", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0038152 [Term] id: UBERON:0001688 name: incus def: "The incus or anvil is the anvil-shaped small bone or ossicle in the middle ear. It connects the malleus to the stapes. It was first described by Alessandro Achillin of Bologna. The incus transmits sound vibrations from the malleus to the stapes. The incus only exists in mammals, and is derived from a reptilian upper jaw bone, the quadrate bone. Embryologically it is derived from the first pharyngeal arch along with the rest of the bones of mastication, such as the maxilla and mandible. [WP,unvetted]." [Wikipedia:Incus] subset: uberon_slim synonym: "quadrate - incus" BROAD [VHOG:0000689] xref: FMA:52752 ! Incus xref: GAID:866 ! incus xref: MA:0001215 ! incus xref: ncithesaurus:Incus ! Incus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/df/Gray917.png/200px-Gray917.png xref: EMAPA:18583 ! incus xref: MESH:A09.246.397.247.362 ! incus xref: VHOG:0000689 ! quadrate - incus (also: UBERON:0006597 'quadrate bone') is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0001686 ! auditory ossicle relationship: develops_from UBERON:0004362 {source="Kardong"} ! pharyngeal arch 1 relationship: develops_from UBERON:0007374 {source="EMAPA-implied"} ! incus cartilage condensation relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: homologous_to UBERON:0006597 ! quadrate bone xref: SCTID:272649008 ! Entire incus xref: http://upload.wikimedia.org/wikipedia/commons/d/df/Gray917.png property_value: homology_notes "According to this theory (Reichert-Gaupp theory), the mammalian stapes is derived from the reptilian columella, the incus from the quadrate and the malleus from the articular (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000689", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0021181 [Term] id: UBERON:0011599 name: lenticular process of incus def: "the long ventral process of the incus which articulates with the stapes" [http://palaeos.com/vertebrates/glossary/glossaryJL.html] comment: the lenticular process may be homologous to the shaft of the stapes and result from fusion of the former quadrate- stapes articulation. This speculation is consistent with the observation that artiodactyls have a very short lenticular process (Thewissen & Hussain (1993)), with perhaps greater length to the corresponding process of the stapes[http://palaeos.com/vertebrates/bones/ear/incus.html] synonym: "processus lenticularis (incus)" EXACT [FMA:52775] synonym: "processus lenticularis" BROAD [] synonym: "lenticular process" BROAD [] synonym: "incus crus longum" EXACT [http://palaeos.com] is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0001688 {source="FMA"} ! incus relationship: develops_from UBERON:0005689 ! 2nd arch mesenchyme xref: FMA:52775 ! lenticular process of incus xref: SCTID:368928003 ! Entire lenticular process of incus xref: http://palaeos.com/vertebrates/bones/ear/images/Incus3.gif [Term] id: UBERON:0006597 name: quadrate bone def: "Ossified pars articularis of the palatoquadrate cartilage." [AAO:0000525, Wikipedia:Quadrate_bone] comment: Taxon notes: In snakes, the quadrate bone has become elongated and very mobile, and contributes greatly to their ability to swallow very large prey items. In mammals the articular and quadrate bones have migrated to the middle ear and are known as the malleus and incus. AO notes: Endochondral bone that commonly articulates with the ectopterygoid anteriorly, the metapterygoid dorsally, and the symplectic postero-medially. The quadrate is formed from the posterior part of the palatoquadrate cartilage, or pars quadrata. The quadrate is a paired bone.[TAO:0000621] synonym: "quadrate - incus" BROAD [VHOG:0000689] synonym: "quadrate bone" EXACT [AAO:0000525] synonym: "quadrate" EXACT [TAO:0000621] xref: AAO:0000525 ! quadrate bone xref: ZFA:0000621 ! quadrate xref: VHOG:0000689 ! quadrate - incus (also: UBERON:0001688 'incus') xref: EFO:0003547 ! quadrate xref: TAO:0000621 ! quadrate is_a: UBERON:0002513 ! endochondral bone relationship: develops_from UBERON:0004752 {source="ZFA"} ! palatoquadrate cartilage relationship: part_of UBERON:0003108 {source="AAO"} ! suspensorium relationship: part_of UBERON:0003277 ! skeleton of upper jaw relationship: in_lateral_side_of UBERON:0003277 ! skeleton of upper jaw relationship: homologous_to UBERON:0001688 {source="Wikipedia:Incus"} ! incus relationship: never_in_taxon NCBITaxon:40674 ! Mammalia property_value: external_definition "Endochondral bone that commonly articulates with the ectopterygoid anteriorly, the metapterygoid dorsally, and the symplectic postero-medially. The quadrate is formed from the posterior part of the palatoquadrate cartilage, or pars quadrata. The quadrate is a paired bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000621", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps quadrate-hyomandibula joint (TAO:0001801)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000621", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps quadrate-metapterygoid joint (TAO:0001803)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000621", date_retrieved="2012-08-14"} property_value: external_comment "The quadrate commonly has a triangular shape, with its lower vertex, or condyle, for articulation with the lower jaw, and an elongate postero-ventral or postero-dorsal elongate process. The presence of an elongate postero-ventral or postero-dorsal process is a synapomorphy of teleosts (Arratia and Schultze, 1990; Arratia, 1999).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000621", date_retrieved="2012-09-06", source="Curator"} property_value: homology_notes "According to this theory (Reichert-Gaupp theory), the mammalian stapes is derived from the reptilian columella, the incus from the quadrate and the malleus from the articular (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000689", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001689 ! malleus name: malleus def: "The malleus or hammer is a hammer-shaped small bone or ossicle of the middle ear which connects with the incus and is attached to the inner surface of the eardrum. The word is Latin for hammer. It transmits the sound vibrations from the eardrum to the incus. The malleus is unique to mammals, and evolved from a lower jaw bone in basal amniotes called the articular, which still forms part of the jaw joint in reptiles. Embryologically it is derived from the first pharyngeal arch along with the rest of the bones of mastication, such as the maxilla and mandible. [WP,unvetted]." [Wikipedia:Malleus] subset: uberon_slim xref: FMA:52753 ! Malleus xref: GAID:867 ! malleu xref: MA:0001216 ! malleus xref: ncithesaurus:Malleus ! Malleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Gray916.png/200px-Gray916.png xref: EMAPA:18584 ! malleus xref: MESH:A09.246.397.247.524 ! malleu xref: VHOG:0000690 ! anguloarticular - malleus (also: UBERON:0004744 'articular/anguloarticular') is_a: UBERON:0001686 ! auditory ossicle relationship: develops_from UBERON:0010054 {source="cjm"} ! malleus cartilage condensation relationship: develops_from UBERON:0004362 {source="Kardong"} ! pharyngeal arch 1 relationship: develops_from UBERON:0003107 {source="Wikipedia"} ! Meckel's cartilage relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia xref: SCTID:264090005 ! Entire malleus synonym: "Malleus" RELATED LATIN [Wikipedia:Malleus] xref: http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray916.png property_value: homology_notes "According to this theory (Reichert-Gaupp theory), the mammalian stapes is derived from the reptilian columella, the incus from the quadrate and the malleus from the articular (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000690", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0024631 [Term] id: UBERON:0004744 name: articular/anguloarticular def: "." [Wikipedia:Articular] comment: Editor notes: We create different classes for articular and malleus, in contrast to VHOG. Taxon notes (from VHOG): "According to this theory [Reichert-Gaupp theory], the mammalian stapes is derived from the reptilian columella, the incus from the quadrate and the malleus from the articular [...]" Gerrie J, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948) 62:339-357. Note that TAO has a distinct class for articular - in fact we need (at least) 3 classes here - articular, anguloarticular and malleus, arranged into a single VHOG group // TODO - resolve part_of relationships synonym: "articular" EXACT [ZFA:0000467] synonym: "angulaire" RELATED [AAO:0000028] synonym: "angulare" RELATED [AAO:0000028] synonym: "dermarticulare" RELATED [AAO:0000028] synonym: "goniale" RELATED [AAO:0000028] synonym: "operculo angulaire" RELATED [AAO:0000028] synonym: "anguloarticular" EXACT [ZFA:0000467] xref: AAO:0000028 ! articular xref: TAO:0000467 ! anguloarticular xref: ZFA:0000467 ! anguloarticular xref: EFO:0003530 ! anguloarticular xref: VHOG:0000690 ! anguloarticular - malleus (also: UBERON:0001689 'malleus') is_a: UBERON:0008907 {source="ZFA"} ! dermal bone is_a: UBERON:0002513 {source="ZFA"} ! endochondral bone relationship: overlaps UBERON:0003113 {source="ZFA-modifed", source="cjm"} ! dermatocranium relationship: overlaps UBERON:0003278 {source="AAO"} ! skeleton of lower jaw relationship: develops_from UBERON:0011002 {source="ZFA"} ! articular cartilage condensation relationship: homologous_to UBERON:0001689 {source="VHOG"} ! malleus property_value: external_definition "Endochondral ossification of the posterior articular part of Meckel's cartilage.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000028", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Dermal and endochondral compound bone that results from the fusion of the dermal angular and the endochondral articular and forms the posterior part of the lower jaw. It articulates with the dentary anteriorly and with the retroarticular postero-medially. The anguloarticular is paired.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000467", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from articular bone (TAO:0001805)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000467", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps dentary-anguloarticular joint (TAO:0001749)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000467", date_retrieved="2012-08-14"} synonym: "anguloarticular - malleus" EXACT [VHOG:0000690] synonym: "angulo-articular" EXACT [TAO:0000467] property_value: external_comment "The presence of an anguloarticular is interpreted as a synapomorphy of the Clupeocephala (Patterson and Rosen, 1977; Arratia, 1999).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000467", date_retrieved="2012-09-06", source="Curator"} property_value: homology_notes "According to this theory (Reichert-Gaupp theory), the mammalian stapes is derived from the reptilian columella, the incus from the quadrate and the malleus from the articular (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000690", ontology="VHOG", source="DOI:10.1017/S0022215100009087 Gerrie J\, The phylogeny of the mammalian tympanic cavity and auditory ossicles. The Journal of Laryngology and Otology (1948", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0011171 ! jaw joint name: jaw joint def: "Skeletal joint that articulates bones of upper and lower jaw." [UBERON:cjm, http://evolution.berkeley.edu/evolibrary/article/evograms_05] comment: Some synapsids retained two pairs of jaw joints - quadrate-articular and tempero-mandibular, but this unusual paired condition did not last long[http://evolution.berkeley.edu] is_a: UBERON:0002217 {source="abduced"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0003277 ! skeleton of upper jaw intersection_of: connects UBERON:0003278 ! skeleton of lower jaw [Term] id: UBERON:0011170 name: quadrate-articular joint def: "A skeletal joint that connects quadrate and articular bones." [http://evolution.berkeley.edu/evolibrary/article/evograms_05, UBERON:cjm] comment: Usage notes: see comments for UBERON:0004744 articular/anguloarticular. Taxon notes: over time, the synapsids' quadrate-articular jaw joint (which the rest of the tetrapods possess) was replaced by a dentary-squamosal joint (which all living mammals possess), while the quadrate and articular migrated, shrank, and became part of the complex of middle ear bones.[http://evolution.berkeley.edu/evolibrary/article/evograms_05] synonym: "quadrate-anguloarticular joint" RELATED [ZFA:0005484] is_a: UBERON:0011171 ! jaw joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0004744 ! articular/anguloarticular intersection_of: connects UBERON:0006597 ! quadrate relationship: never_in_taxon NCBITaxon:32525 {source="http://evolution.berkeley.edu"} ! Theria xref: TAO:0001802 ! quadrate-anguloarticular joint xref: ZFA:0005484 ! quadrate-anguloarticular joint property_value: external_definition "Joint that articulates quadrate and anguloarticular bones. Quadrate-articular joint is paired.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001802", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0010996 ! articular cartilage of joint name: articular cartilage of joint def: "A thin layer of cartilage, usually hyaline, on the articular surface of bones in synovial joints." [BTO:0001572] synonym: "hyaline cartilage" RELATED [BTO:0001572] synonym: "cartilago articularis" EXACT [FMA:12264] synonym: "articular cartilage" EXACT [MA:0000487] synonym: "joint-associated cartilage" RELATED [AEO:0000179] subset: uberon_slim subset: vertebrate_core is_a: UBERON:0001994 {source="MA"} ! hyaline cartilage relationship: part_of UBERON:0002217 {source="Wikipedia"} ! synovial joint disjoint_from: UBERON:0011002 ! articular cartilage condensation xref: BTO:0001572 ! articular cartilage xref: FMA:12264 ! articular cartilage xref: GAID:101 ! articular cartilage xref: galen:ArticularCartilage xref: MA:0000487 ! articular cartilage xref: EFO:0001902 ! articular cartilage xref: MESH:A02.165.165 ! articular cartilage xref: SCTID:305026006 ! Entire articular cartilage xref: ncithesaurus:Articular_Cartilage ! Articular Cartilage xref: UMLS:C0007303 xref: AEO:0000179 ! joint-associated cartilage [Term] id: UBERON:0011002 ! articular cartilage condensation name: articular cartilage condensation synonym: "articular cartilages" BROAD PLURAL [ZFA:0001644] is_a: UBERON:0011004 {source="ZFA"} ! pharyngeal arch cartilage xref: ZFA:0001644 ! articular cartilage xref: TAO:0001670 ! articular cartilage [Term] id: UBERON:0001086 name: obsolete articular cartilage is_obsolete: true comment: obsoleted as it conflated two distinct classes consider: UBERON:0011002 ! articular cartilage condensation consider: UBERON:0010996 ! articular cartilage of joint [Term] id: UBERON:0001690 name: ear def: "Sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GO:0042471, Wikipedia:Ear] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "auditory apparatus" RELATED [] synonym: "auris" RELATED [BTO:0000368] xref: BTO:0000368 xref: EFO:0000826 ! ear xref: EHDAA:502 ! ear xref: FMA:52780 ! Ear xref: GAID:62 ! ear xref: galen:Ear xref: VHOG:0000330 ! ear xref: MA:0000236 ! ear xref: MAT:0000138 ! ear xref: MIAA:0000138 ! ear xref: ncithesaurus:Ear xref: NIF_GrossAnatomy:birnlex_1062 ! Ear xref: OpenCyc:Mx4rvVjL05wpEbGdrcN5Y29ycA xref: XAO:0000189 ! auditory apparatus xref: OpenCyc:Mx4rvViXS5wpEbGdrcN5Y29ycA ! earring xref: OpenCyc:Mx4rvVjL05wpEbGdrcN5Y29ycA ! ear xref: EHDAA2:0000423 ! ear xref: EMAPA:16193 ! ear xref: MESH:A01.456.313 ! ear xref: EV:0100353 ! auditory apparatus is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0000033 ! head relationship: part_of UBERON:0002105 ! auditory system relationship: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest xref: AAO:0011014 ! auditory apparatus xref: SCTID:1910005 ! Entire ear subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/b/b8/Ear.jpg property_value: external_definition "The organ of hearing and of equilibrium. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000330", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/ear", source="http://bgee.unil.ch/"} property_value: homology_notes "Both vertebrate and invertebrate auditory organs are thought to have evolved from primitive mechanosensors, but the nature of the ancestral structure and the evolutionary trajectories followed in distinct animal lineages remain unknown. In particular, we do not know how many types of mechanosensor existed in the protostome-deuterostome ancestor from which insects and vertebrates evolved or whether the PDA had an auditory organ.[well established][VHOG]" xsd:string {external_class="VHOG:0000330", ontology="VHOG", source="DOI:10.1002/dvdy.20207 Boekhoff-Falk G\, Hearing in Drosophila: Development of Johnston's organ and emerging parallels to vertebrate ear development. Developmental Dynamics (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "auricular" xsd:string xref: UMLS:C0013443 [Term] id: UBERON:0011635 name: splenial bone def: "The splenial is a small bone in the lower jaw of reptiles, amphibians and birds, usually located on the lingual side (closest to the tongue) between the angular and suprangular." [Wikipedia:Splenial] synonym: "splenial" EXACT [AAO:0000573] is_a: UBERON:0008907 {source="AAO"} ! dermal bone relationship: part_of UBERON:0003278 {source="AAO"} ! skeleton of lower jaw relationship: part_of UBERON:0003113 {source="Kardong", notes="mandibular series"} ! dermatocranium xref: AAO:0000573 ! splenial xref: http://palaeos.com/vertebrates/bones/dermal/images/Dentary1.gif [Term] id: UBERON:0011636 name: surangular bone def: "The surangular is a dermal bone of the lower jaw. It typically covers much of the dorsal and lateral surface of the posterior jaw and variably extends onto the medial (inside) surface. The surangular articulates with and supports the articular, which forms the jaw joint with the quadrate in most vertebrates, and is in turn supported by the angular. More distally, the surangular bridges the mandibular fenestra, if one is present. It may also bear a raised dorsal coronoid process, an important attachment site for the mandibular adductors. At its distal (or rostral) end, the surangular meets the dentary, the main tooth-bearing bone of the lower jaw in most vertebrates." [http://palaeos.com/vertebrates/bones/dermal/mandibular-surangular.html] comment: Taxon notes: "Nevertheless, it is not completely clear that this[osteichthyans] surangular is homologous with the surangular in tetrapods"[paleos] In some lepospondyls, and in frogs and salamanders, the surangular is absent. However, it becomes increasingly significant in the anthracosaur lineage. In turtles, it is one of the two principle bones of the lower jaw. In lepidosaurs, it is less important because of the development of a separate coronoid bone. In advanced lizards and pythonomorphs, it may fuse with the articular and perhaps other bones and loses its separate identity. In syanapsids, a secondary jaw joint develops between the surangular and the squamosal, which becomes the unique mammalian jaw articulation. However, the surangular fuses with the dentary and becomes the unitary mammalian "mandible" without a separate identity is_a: UBERON:0008907 {source="TAO", source="Palaeos"} ! dermal bone relationship: part_of UBERON:0003278 {source="paleos.com"} ! skeleton of lower jaw relationship: part_of UBERON:0003113 {source="Kardong", notes="mandibular series"} ! dermatocranium relationship: connected_to UBERON:0004744 ! articular/anguloarticular xref: TAO:0002287 ! surangular synonym: "surangular" EXACT [TAO:0002287] synonym: "suprangular" RELATED [http://purl.obolibrary.org/obo/uberon/tracker/164, Wikipedia:Suprangular] synonym: "supraangular" RELATED [http://purl.obolibrary.org/obo/uberon/tracker/164] synonym: "supra-angular" RELATED [http://purl.obolibrary.org/obo/uberon/tracker/164] synonym: "suprangular bone" RELATED [http://purl.obolibrary.org/obo/uberon/tracker/164] synonym: "supraangular bone" RELATED [http://purl.obolibrary.org/obo/uberon/tracker/164] synonym: "supra-angular bone" RELATED [http://purl.obolibrary.org/obo/uberon/tracker/164] xref: http://palaeos.com/vertebrates/bones/dermal/images/Surangular1.gif xref: http://palaeos.com/vertebrates/bones/dermal/images/Dentary1.gif property_value: external_definition "Dermal bone of the suspensorium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002287", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0011637 name: prearticular bone def: "Osseous element of intramembranous origin that extends along the lingual margin of Meckel's cartilage." [AAO:0000458] is_a: UBERON:0008907 {source="AAO"} ! dermal bone relationship: part_of UBERON:0003278 {source="AAO"} ! skeleton of lower jaw relationship: part_of UBERON:0003113 {source="Kardong", notes="mandibular series"} ! dermatocranium xref: AAO:0000458 ! prearticular synonym: "prearticular" EXACT [AAO:0000458] xref: http://palaeos.com/vertebrates/bones/dermal/images/Dentary1.gif [Term] id: UBERON:0011079 name: angular bone def: "Dermal bone that is located posterior to the dentary and lateral to the articular and retroarticular bones of the lower jaw. The angular forms the outer dermal sheet of the posterior part of the lower jaw. The angular bears a portion of the mandibular sensory canal. The angular is a paired bone." [TAO:0001669, Wikipedia:Angular_bone] comment: The angular fuses with the articular bone in clupeocephalans forming the anguloarticular. synonym: "postoperculare" RELATED [AAO:0000010] synonym: "praearticulare" RELATED [AAO:0000010] synonym: "angular" BROAD [AAO:0000010] is_a: UBERON:0008907 {source="TAO"} ! dermal bone relationship: part_of UBERON:0003113 {source="Kardong", notes="mandibular series"} ! dermatocranium relationship: part_of UBERON:0003278 {source="AAO"} ! skeleton of lower jaw relationship: in_lateral_side_of UBERON:0003278 {source="AAO"} ! skeleton of lower jaw xref: TAO:0001669 ! angular bone xref: AAO:0000010 ! angular xref: ZFA:0001645 ! angular bone [Term] id: UBERON:0013113 name: angular/surangular bone def: "Bone formed from the fusion of angular and surangular bones. Found in snakes" [ISBN10:0073040584] is_a: UBERON:0008907 ! dermal bone relationship: part_of UBERON:0003113 ! dermatocranium relationship: has_fused_element UBERON:0011079 ! angular bone relationship: has_fused_element UBERON:0011636 ! surangular bone [Term] id: UBERON:0002218 ! tympanic ring name: tympanic ring def: "a C-shaped membranous bone that provides physical support to the tympanic membrane. The tympanic ring develops sequentially from an initial primordium in the first branchial arch growing in a circumferential fashion around the first pharyngeal cleft into the second branchial arch (Mallo and Gridley, 1996). In most mammals, the tympanic ring exists only during embryonic life, when it coordinates proper development and positioning of the eardrum (see below), and then becomes integrated into the temporal bone[PMID]." [MP:0000030, PMID:11237469] comment: AO notes: in FMA, the tympanic ring is an anatomical line. Howevever PMID:11237469 states: "the tympanic ring, which serves as support for the tympanic membrane, directs invagination of the first pharingeal cleft ectoderm to form the external acoustic meatus (EAM), which provides the outer layer of the membrane". Taxon notes: check amphibians - in AAO "Funnel-like ring structure located lateral to the ventral ramus of the squamosal, beneath the skin; it provides support to the tympanic membrane". Gene notes: Gsc and Prx1 are essential for tympanic ring development synonym: "tympanic anulus" RELATED [] synonym: "tympanic annulus" RELATED [] synonym: "tympanic membrane annulus" RELATED [] synonym: "ectotympanic ring" RELATED [Wikipedia:Ectotympanic_ring] synonym: "os tympanicum" RELATED [EMAPA:19197] xref: MA:0001225 ! tympanic ring xref: AAO:0000615 ! tympanic_annulus xref: EMAPA:19197 ! tympanic ring xref: SCTID:95952001 ! Entire tympanic anulus is_a: UBERON:0002514 {source="PMID:11237469"} ! intramembranous bone relationship: part_of UBERON:0001756 {source="MA"} ! middle ear property_value: external_definition "Funnel-like ring structure located lateral to the ventral ramus of the squamosal, beneath the skin; it provides support to the tympanic membrane.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000615", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of plectral apparatus (AAO:0000443)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000615", date_retrieved="2012-06-20"} [Term] id: UBERON:0010066 name: tympanic plate def: "The tympanic part of the temporal bone is a curved plate of bone lying below the squama and in front of the mastoid process." [Wikipedia:Tympanic_part_of_the_temporal_bone] comment: Consider merging with tympanic ring. See discussion page on wikipedia page for ectotympanic. todo: distinguish ecto- and ento- tympanics synonym: "pars tympanica" RELATED [Wikipedia:Tympanic_part_of_the_temporal_bone] synonym: "tympanic part" RELATED [Wikipedia:Tympanic_part_of_the_temporal_bone] synonym: "tympanic bone" RELATED [Wikipedia:Tympanic_part_of_the_temporal_bone] synonym: "ectotympanic bone" RELATED [Wikipedia:Ectotympanic] synonym: "ectotympanic" RELATED [Wikipedia:Ectotympanic] synonym: "pars tympanica (os temporale)" EXACT [FMA:52880] synonym: "tympanic part of temporal bone" EXACT [FMA:52880] synonym: "pars tympanica ossis temporalis" RELATED LATIN [Wikipedia:Tympanic_part_of_the_temporal_bone] is_a: UBERON:0005913 {source="cjm"} ! zone of bone organ relationship: part_of UBERON:0001678 ! temporal bone relationship: develops_from UBERON:0002218 ! tympanic ring relationship: homologous_to UBERON:0011079 {source="Kardong"} ! angular bone xref: FMA:52880 ! tympanic part of temporal bone xref: http://upload.wikimedia.org/wikipedia/commons/9/96/Gray137.png xref: SCTID:138773005 ! Entire tympanic part of temporal bone [Term] id: UBERON:0013190 name: entotympanic bone def: "Entotympanics are independent elements present in the auditory bullae of various eutherians" [doi:10.1023/A:1020538313412] comment: endochondral [doi:10.1023/A:1020538313412] synonym: "entotyympanic" RELATED [] is_a: UBERON:0005913 {source="cjm"} ! zone of bone organ relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0013173 name: anterior part of tympanic bone xref: FMA:56478 ! anterior surface of tympanic plate xref: SCTID:368942006 ! Entire anterior wall of tympanic cavity synonym: "anterior surface of tympanic plate" EXACT [FMA:56478] synonym: "anterior wall of tympanic cavity" EXACT [] synonym: "anterior wall of tympanum" EXACT [] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0010066 ! tympanic plate xref: ncithesaurus:Anterior_Wall_of_the_Tympanum ! anterior wall of the tympanum xref: UMLS:C1510916 [Term] id: UBERON:0008959 name: auditory bulla def: "a hollow bony structure on the ventral, posterior portion of the skull of placental mammals that encloses parts of the middle and inner ear. In most species, it is formed by the tympanic part of the temporal bone." [Wikipedia:Auditory_bulla] comment: In extant primates, the structure is found in tarsiers, lemurs, and lorises[WP]. When present in marsupials, it usually forms the alisphenoid; in placentals variously constructed of ectotympanic, entotympanic, petrosal, or a combination of these and others[Rose] Comment: may be formed from entotympanic and ectotympanic synonym: "auditory bullae" RELATED PLURAL [] synonym: "bulla" BROAD [] synonym: "tympanic bulla" RELATED [] synonym: "bulla tympanica" RELATED LATIN [UBERON:cjm] synonym: "sigmoid process" NARROW [] is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0001690 ! ear relationship: part_of UBERON:0003113 {source="Kardong"} ! dermatocranium relationship: surrounds UBERON:0004114 {source="Rose"} ! tympanic cavity relationship: only_in_taxon NCBITaxon:32525 {source="Wikipedia"} ! Theria relationship: homologous_to UBERON:0011079 {source="Kardong"} ! angular bone xref: http://upload.wikimedia.org/wikipedia/commons/a/af/Toothed_whale_sound_production.png [Term] id: UBERON:0013174 name: sigmoid process of tympanic bone def: "a wavy crest externally on the tympanic bone of cetaceans." [http://palaeos.com/vertebrates/glossary/glossaryS.html] synonym: "sigmoid process" EXACT [] synonym: "sigmoid process of auditory bulla" EXACT [] is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0008959 ! auditory bulla relationship: only_in_taxon NCBITaxon:9721 ! Cetacea [Term] id: UBERON:0013175 name: nasal air sac synonym: "blowhole air sac" EXACT [] def: "An air sac opening into the passage of the blowhole that is hypothesized to be involved in echolocation" [http://palaeos.com/vertebrates/cetartiodactyla/cetacea.html] comment: May be positioned distally or frontally is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001707 ! nasal cavity relationship: has_function_in GO:0050959 ! echolocation relationship: only_in_taxon NCBITaxon:9721 ! Cetacea [Term] id: UBERON:0013176 name: phonic lip comment: Function notes: When the lips snap together during click production, vibrations in the dorsal bursae are likely produced ISBM10:0120885522. Large and cornified in sperm whales. Editor notes: requires review w.r.t location in physeter vs other odontocetes synonym: "phonic lips" RELATED PLURAL [] synonym: "monkey lips" RELATED [http://palaeos.com/vertebrates/cetartiodactyla/cetacea.html] synonym: "museau de singe@fr" RELATED [] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0013188 {notes="check for sperm whales"} ! monkey lips dorsal bursa complex relationship: located_in UBERON:0013177 ! dorsal bursa relationship: has_function_in GO:0050959 ! echolocation relationship: only_in_taxon NCBITaxon:9721 {notes="absent in baleen whales"} ! Cetacea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Delphinschaedel.svg/500px-Delphinschaedel.svg.png [Term] id: UBERON:0013177 name: dorsal bursa synonym: "dorsal bursae" RELATED PLURAL [] synonym: "fatty dorsal bursa" RELATED [] is_a: UBERON:0001013 ! adipose tissue relationship: part_of UBERON:0013188 {notes="check for sperm whales"} ! monkey lips dorsal bursa complex relationship: in_lateral_side_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:9721 ! Cetacea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Delphinschaedel.svg/500px-Delphinschaedel.svg.png [Term] id: UBERON:0013178 name: anterior dorsal bursa synonym: "anterior bursa" BROAD [] is_a: UBERON:0013177 ! dorsal bursa [Term] id: UBERON:0013179 name: posterior dorsal bursa synonym: "posterior bursa" BROAD [] comment: right posterior dorsal bursa may be homologous to spermaceti organ is_a: UBERON:0013177 ! dorsal bursa [Term] id: UBERON:0013180 name: bursal cartilage is_a: UBERON:0007844 ! cartilage element relationship: located_in UBERON:0013177 ! dorsal bursa relationship: part_of UBERON:0013188 ! monkey lips dorsal bursa complex [Term] id: UBERON:0013181 name: blowhole ligament comment: Likely involved in regulating air movement in perhaps whistle production ISBM10:0120885522 is_a: UBERON:0008845 ! nonskeletal ligament relationship: part_of UBERON:0013188 ! monkey lips dorsal bursa complex [Term] id: UBERON:0013182 name: core of melon organ synonym: "melon core" RELATED [] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0008960 ! melon organ [Term] id: UBERON:0013188 ! monkey lips dorsal bursa complex name: monkey lips dorsal bursa complex def: "A structure consisting of a pair of anterior and posterior dorsal bursae in which a pair of phonic lips are embedded, along with the bursal cartilage and a blowhole ligament" [ISBM10:0120885522] comment: Taxon notes: all odontocetes except sperm whales posses two bilaterally placed MLDB complexes, placed just below the floor of the vestibular sac synonym: "MLDB complex" EXACT [] is_a: UBERON:0000481 ! multi-tissue structure relationship: in_lateral_side_of UBERON:0000033 ! head relationship: located_in UBERON:0001707 ! nasal cavity relationship: has_function_in GO:0050959 {source="ISBM10:0120885522"} ! echolocation relationship: only_in_taxon NCBITaxon:9721 ! Cetacea [Term] id: UBERON:0013189 name: junk chamber comment: May be homologous to melon organ synonym: "junk bodies" RELATED PLURAL [] synonym: "junk body" RELATED [] synonym: "junk organ" RELATED [] synonym: "junk" RELATED [] is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:9753 ! Physeter xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3b/Sperm_whale_head_anatomy.svg/1000px-Sperm_whale_head_anatomy.svg.png [Term] id: UBERON:0010053 name: echolocation organ intersection_of: UBERON:0000062 ! organ intersection_of: has_function_in GO:0050959 ! echolocation [Term] id: UBERON:0008960 name: melon organ def: "The melon is an ovoid-shaped, fatty organ found in the forehead of all toothed whales (odontocetes), including dolphins and porpoises (Cranford et al., 1996; Harper, C. J., et al., 2008) and believed to be used in echolocation" [Wikipedia:Melon_(whale)] synonym: "melon" RELATED [] is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0000033 ! head relationship: has_function_in GO:0050959 ! echolocation relationship: only_in_taxon NCBITaxon:9721 ! Cetacea [Term] id: UBERON:0013477 name: blowhole def: "A hole at the top of a cetacean's head through which the animal breathes air" [Wikipedia:Blowhole_(anatomy)] comment: Taxon notes: Baleen whales have two blowholes positioned in a V-shape while toothed whales have only one blowhole. The blowhole of a sperm whale, a toothed whale, is located left of centre in the frontal area of the snout, and is actually its left nostril, while the right nostril lacks an opening to the surface despite the fact that its nasal passage is otherwise well developed. synonym: "blowhole slit" NARROW [] is_a: UBERON:0005928 ! external naris relationship: only_in_taxon NCBITaxon:9721 ! Cetacea [Term] id: UBERON:0002105 name: vestibulo-auditory system def: "A sensory system for the sense of hearing[WP]." [Wikipedia:Auditory_system] comment: Auditory system is general anatomical term in FMA subset: uberon_slim subset: functional_classification subset: vertebrate_core synonym: "auditory organ system" EXACT [] synonym: "auditory system" RELATED [] synonym: "auditory/vestibular system" RELATED [] synonym: "vestibuloauditory system" EXACT [] synonym: "vestibuloauditory system" RELATED [] xref: AAO:0000631 ! vestibuloauditory_system xref: FMA:7192 ! Auditory system xref: FMA:78500 ! Vestibulo-auditory system xref: TAO:0001138 ! vestibuloauditory system xref: MA:0002443 ! auditory system xref: XAO:0003195 ! vestibuloauditory system xref: ZFA:0001138 ! vestibuloauditory system xref: ncithesaurus:Auditory_System ! Auditory System xref: OpenCyc:Mx4rvViwtJwpEbGdrcN5Y29ycA ! auditory system xref: NIF_GrossAnatomy:nlx_anat_090817 ! Auditory system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7c/HumanEar.jpg/200px-HumanEar.jpg is_a: UBERON:0001032 ! sense organ system intersection_of: UBERON:0001032 ! sense organ system intersection_of: capable_of GO:0007605 ! sensory perception of sound relationship: capable_of GO:0007605 ! sensory perception of sound xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Anatomy_of_the_Human_Ear.svg property_value: external_definition "The sensory system used for balance and hearing.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000631", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C0587901 [Term] id: UBERON:0004681 ! vestibular system name: vestibular system def: "The vestibular system, which contributes to our balance and our sense of spatial orientation, is the sensory system that provides the dominant input about movement and equilibrioception. Together with the cochlea, a part of the auditory system, it constitutes the labyrinth of the inner ear, situated in the vestibulum in the inner ear. As our movements consist of rotations and translations, the vestibular system comprises two components: the semicircular canal system, which indicate rotational movements; and the otoliths, which indicate linear accelerations. The vestibular system sends signals primarily to the neural structures that control our eye movements, and to the muscles that keep us upright. The projections to the former provide the anatomical basis of the vestibulo-ocular reflex, which is required for clear vision; and the projections to the muscles that control our posture are necessary to keep us upright." [Wikipedia:Vestibular_system] comment: note that FMA and NIF have no part information for this class. This is a GAT in FMA synonym: "vestibular system" EXACT [NIF_GrossAnatomy:nlx_anat_090819] synonym: "vestibular organ system" EXACT [FMA:7193] xref: FMA:7193 ! vestibular system xref: NIF_GrossAnatomy:nlx_anat_090819 ! Vestibular system xref: BTO:0003381 ! vestibular system intersection_of: UBERON:0001032 ! sense organ system intersection_of: capable_of GO:0050957 ! equilibrioception relationship: has_function_in GO:0060005 ! vestibular reflex xref: SCTID:361533001 ! Structure of vestibular system [Term] id: UBERON:0006585 name: vestibular organ synonym: "balance organ" EXACT [UBERON:cjm] xref: NIF_GrossAnatomy:birnlex_2519 ! Vestibular organ intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0004681 ! vestibular system def: "An organ that is part of a vestibular system." [OBOL:automatic] [Term] id: UBERON:0011005 name: endocardium of auricle synonym: "auricle endocardium" EXACT [FMA:13234] comment: Note in EHDAA2 this is an epithelium that is part of the endocardium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0006618 ! atrium auricular region xref: FMA:13234 ! endocardium of auricle def: "An endocardium that is part of a atrium auricular region." [OBOL:automatic] [Term] id: UBERON:0011006 name: endocardium of left auricle synonym: "left auricle endocardium" EXACT [FMA:13236] synonym: "left atrium auricular region endocardium" EXACT [EHDAA2:0000277] intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0006630 ! left atrium auricular region xref: FMA:13236 ! endocardium of left auricle xref: EHDAA2:0000277 ! left atrium auricular region endocardium xref: VHOG:0001231 ! left auricle endocardium synonym: "left auricle endocardial tissue" RELATED [VHOG:0001231] def: "An endocardium that is part of a left atrium auricular region." [OBOL:automatic] [Term] id: UBERON:0011007 name: endocardium of right auricle synonym: "right auricle endocardium" EXACT [FMA:13235] intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0006631 ! right atrium auricular region xref: FMA:13235 ! endocardium of right auricle xref: EHDAA2:0000292 ! right atrium auricular region endocardium def: "An endocardium that is part of a right atrium auricular region." [OBOL:automatic] [Term] id: UBERON:0003378 name: cardiac muscle of auricular region xref: FMA:84279 ! cardiac muscle tissue of auricle synonym: "cardiac muscle tissue of auricle" EXACT [FMA:84279] synonym: "auricular region heart muscle" EXACT [] intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0006618 ! atrium auricular region relationship: part_of UBERON:0001133 ! cardiac muscle tissue def: "A cardiac muscle tissue that is part of a atrium auricular region." [OBOL:automatic] [Term] id: UBERON:0009779 name: cardiac muscle tissue of right auricle is_a: UBERON:0003378 {source="FMA"} ! cardiac muscle of auricular region intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0006631 ! right atrium auricular region xref: FMA:84280 ! cardiac muscle tissue of right auricle xref: EMAPA:16826 ! cardiac muscle of right auricular region xref: EMAPA:17324 ! cardiac muscle of auricular region of right atrium xref: EHDAA2:0004168 ! left atrium auricular region heart muscle synonym: "left atrium auricular region heart muscle" EXACT [EHDAA2:0004168] synonym: "cardiac muscle of right auricular region" EXACT [EMAPA:16826] xref: VHOG:0000611 ! right auricular region myocardium synonym: "right auricular region myocardium" EXACT [VHOG:0000611] synonym: "right auricular region cardiac muscle" RELATED [VHOG:0000611] def: "A cardiac muscle tissue that is part of a right atrium auricular region." [OBOL:automatic] [Term] id: UBERON:0009780 name: cardiac muscle tissue of left auricle is_a: UBERON:0003378 {source="FMA"} ! cardiac muscle of auricular region intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0006630 ! left atrium auricular region xref: FMA:84281 ! cardiac muscle tissue of left auricle xref: EMAPA:16818 ! cardiac muscle of left auricular region xref: EMAPA:17318 ! cardiac muscle of auricular region of left atrium xref: EHDAA2:0004169 ! right atrium auricular region heart muscle synonym: "right atrium auricular region heart muscle" EXACT [EHDAA2:0004169] synonym: "cardiac muscle of left auricular region" EXACT [EMAPA:16818] def: "A cardiac muscle tissue that is part of a left atrium auricular region." [OBOL:automatic] [Term] id: UBERON:0006618 name: atrium auricular region def: "A small conical pouch projections located on the upper anterior portion of each atrium of the heart." [MP:0010489, Wikipedia:Auricular_appendage] synonym: "auricular appendage" EXACT [] synonym: "auricle of heart" EXACT [FMA:77110] synonym: "atrial auricle" EXACT [MP:0010489] synonym: "heart atrium auriclular region" EXACT [MP:0010489] xref: MA:0002955 ! atrium auricular region xref: FMA:77110 ! Auricle of heart xref: SCTID:305223006 ! Entire auricular appendage is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0002081 ! cardiac atrium disjoint_from: UBERON:0001691 ! external ear synonym: "auricula atrii" EXACT LATIN [FMA:TA, FMA:77110] synonym: "auricle of atrium" EXACT [FMA:77110] synonym: "auricula (cor)" EXACT [FMA:77110] synonym: "cardiac auricle" EXACT [FMA:77110] [Term] id: UBERON:0006630 name: left atrium auricular region def: "a muscular pouch connected to the left atrium of the heart" [Wikipedia:Left_atrial_appendage] synonym: "auricula sinistra" EXACT [Wikipedia:Right_atrial_appendage] synonym: "left auricula" EXACT [Wikipedia:Right_atrial_appendage] synonym: "left auricular appendix" EXACT [Wikipedia:Right_atrial_appendage] synonym: "left atrial appendage" RELATED [MA:0001869] synonym: "left auricular region" BROAD [EMAPA:16816] synonym: "left auricle" EXACT [FMA:7219] xref: MA:0001869 ! left atrium auricular region xref: EHDAA2:0000276 ! left atrium auricular region xref: EHDAA:5343 ! auricular region xref: EMAPA:16816 ! left auricular region xref: FMA:7219 ! Left auricle xref: VHOG:0001229 ! left auricle xref: SCTID:277930000 ! Entire left auricular appendage intersection_of: UBERON:0006618 ! atrium auricular region intersection_of: part_of UBERON:0002079 ! left atrium synonym: "auricula sinistra" RELATED LATIN [Wikipedia:Left_atrial_appendage] xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray494.png synonym: "left auricular appendage" RELATED [FMA:7219] [Term] id: UBERON:0006631 name: right atrium auricular region def: "a small conical muscular pouch attached to the right atrium of the heart." [Wikipedia:Right_atrial_appendage] synonym: "auricula dextra" EXACT [Wikipedia:Right_atrial_appendage] synonym: "right auricula" EXACT [Wikipedia:Right_atrial_appendage] synonym: "right auriculur appendix" EXACT [Wikipedia:Right_atrial_appendage] synonym: "right atrial appendage" RELATED [MA:0001870] synonym: "right auricle" EXACT [FMA:7218] synonym: "right auricular region" BROAD [EMAPA:16824] xref: MA:0001870 ! right atrium auricular region xref: EHDAA2:0000291 ! right atrium auricular region xref: EHDAA:5352 ! auricular region xref: EMAPA:16824 ! right auricular region xref: FMA:7218 ! right auricle xref: VHOG:0001232 ! right auricle xref: SCTID:277713005 ! Entire right auricular appendage intersection_of: UBERON:0006618 ! atrium auricular region intersection_of: part_of UBERON:0002078 ! right atrium synonym: "right auricular appendage" RELATED [FMA:7218] [Term] id: UBERON:0001691 name: external ear def: "Part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull[GO]." [GO:0042473, Wikipedia:External_ear] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "auricular region" BROAD [] synonym: "auricular region of head" EXACT [] synonym: "outer ear" EXACT [] synonym: "auris externa" RELATED [BTO:0002100] xref: EHDAA:3786 ! external ear xref: FMA:52781 ! External ear xref: GAID:104 ! external ear xref: VHOG:0000311 ! external ear xref: MA:0000258 ! outer ear xref: MAT:0000147 ! outer ear xref: MIAA:0000147 ! outer ear xref: ncithesaurus:External_Ear xref: NIF_GrossAnatomy:birnlex_1705 ! Outer ear xref: XAO:0000190 ! external ear xref: BTO:0002100 ! external ear xref: OpenCyc:Mx4rwOHtXJwpEbGdrcN5Y29ycA ! external ear xref: EHDAA2:0000462 ! external ear xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Gray907.png/200px-Gray907.png xref: EMAPA:16991 ! external ear xref: MESH:A09.246.272 ! external ear xref: EV:0100354 ! external ear is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001690 ! ear relationship: never_in_taxon NCBITaxon:9709 {source="Wikipedia"} ! Phocidae xref: AAO:0011037 ! external ear xref: SCTID:181176000 ! Outer ear property_value: external_definition "The external part of the organ, which consists of an outer portion (external auditory meatus) which leads to the tympanum. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000311", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Some species, like Amolops tormotus (Feng et al. 2006), have a cavity in front of the tympanic membrane which is considered to be an ear canal and thus an outer ear. (...) The ancestral lineage of amphibians separated from the mammalian lineage, approximately 350 million years ago, in the paleozoic era. Many of the important developments in the auditory systems emerged after the ancestral paths separated (Manley and Clack 2003). This implies that shared features, like the tympanic middle ear, developed independently in different vertebrate lineages.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000311", ontology="VHOG", source="DOI:10.1007/s00359-008-0327-1 Schoffelen RLM\, Segenhout JM\, Van Dijk P\, Mechanics of the exceptional anuran ear. Journal of Comparative Physiology A (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0000033 ! head xref: EFO:0004221 ! External ear xref: UMLS:C0013453 [Term] id: UBERON:0006616 name: right external ear synonym: "right auricular region" BROAD [FMA:53643] xref: FMA:53643 ! right external ear intersection_of: UBERON:0001691 ! external ear intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:368567003 ! Entire right external ear def: "An external ear that is in the right side of a multi-cellular organism." [OBOL:automatic] [Term] id: UBERON:0006617 name: left external ear synonym: "left auricular region" BROAD [FMA:53644] xref: FMA:53644 ! left external ear intersection_of: UBERON:0001691 ! external ear intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:368589004 ! Entire left external ear def: "An external ear that is in the left side of a multi-cellular organism." [OBOL:automatic] [Term] id: UBERON:0001698 name: foramen ovale of skull def: "one of the larger of the several holes at the base of the skull that transmit nerves through the skull. The foramen ovale is situated in the anterior part of the sphenoid bone, posteriolateral to the foramen rotundum.." [Wikipedia:Foramen_ovale_(skull)] synonym: "foramen ovale" NARROW [AAO:0000169, FMA:53155] synonym: "foramen ovale (skull)" EXACT [FMA:53155] synonym: "foramen ovale basis cranii" EXACT [galen:ForamenOvaleBasisCranii] synonym: "foramen ovale of chondrocranium" EXACT [EMAPA:18711] xref: EHDAA:10627 ! foramen ovale xref: EMAPA:18711 ! foramen ovale of chondrocranium xref: FMA:53155 ! Foramen ovale xref: VHOG:0001189 ! foramen ovale xref: AAO:0000169 ! fenestra_ovalis xref: galen:ForamenOvaleBasisCranii xref: EHDAA2:0000551 ! foramen ovale is_a: UBERON:0005744 ! cranial conduit disjoint_from: UBERON:0004754 ! foramen ovale of heart relationship: part_of UBERON:0003129 ! skull relationship: located_in UBERON:0001677 ! sphenoid bone property_value: external_definition "An aperture in the great wing of the sphenoid for vessels and nerves. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001189", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/foramen+ovale", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004754 ! foramen ovale of heart name: foramen ovale of heart def: "In the fetal heart, the foramen ovale (also ostium secundum of Born or falx septi) allows blood to enter the left atrium from the right atrium. It is one of two fetal cardiac shunts, the other being the ductus arteriosus (which allows blood that still escapes to the right ventricle to bypass the pulmonary circulation). Another similar adaptation in the fetus is the ductus venosus. In most individuals, the foramen ovale (pronounced /fɒˈreɪmən oʊˈvɑːli/) closes at birth. It later forms the fossa ovalis[WP]." [Wikipedia:Foramen_ovale_(heart)] synonym: "ostium secundum of Born" EXACT [Wikipedia:Foramen_ovale_(heart)] synonym: "falx septi" EXACT [Wikipedia:Foramen_ovale_(heart)] synonym: "foramen ovale" NARROW [MA:0001873, galen:ForamenOvale] synonym: "foramen ovale cordis" EXACT [galen:ForamenOvaleCordis] synonym: "Bottalo's foramen" EXACT [FMA:86043] xref: FMA:86043 ! foramen ovale of heart xref: MA:0001873 ! foramen ovale xref: galen:ForamenOvaleCordis xref: EMAPA:18244 ! foramen ovale of interatrial septum is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002085 ! interatrial septum relationship: part_of UBERON:0000922 ! embryo xref: ncithesaurus:Oval_Foramen ! Oval Foramen xref: EHDAA2:0004142 ! foramen ovale of heart xref: SCTID:362015004 ! Entire foramen ovale of heart xref: UMLS:C0016521 [Term] id: UBERON:0001699 name: sensory root of facial nerve def: "The nervus intermedius, or intermediate nerve, is the part of the facial nerve (cranial nerve VII) located between the motor component of the facial nerve and the vestibulocochlear nerve (cranial nerve VIII). It contains the sensory and parasympathetic fibers of the facial nerve. Upon reaching the facial canal, it joins with the motor root of the facial nerve at the geniculate ganglion. [WP,unvetted]." [Wikipedia:Intermediate_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "intermediate nerve" EXACT [] synonym: "Wrisberg's nerve" EXACT [] xref: FMA:53410 ! Sensory root of facial nerve xref: TAO:0000679 ! sensory root of facial nerve xref: ZFA:0000679 ! sensory root of facial nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Gray788.png/200px-Gray788.png is_a: UBERON:0004674 ! facial nerve root relationship: part_of UBERON:0001896 ! medulla oblongata relationship: develops_from UBERON:0002342 {source="Wikipedia"} ! neural crest synonym: "nervus intermedius" EXACT LATIN [FMA:TA, FMA:53410] xref: SCTID:279927001 ! Entire nervus intermedius [Term] id: UBERON:0010287 name: motor root of facial nerve synonym: "facial nerve motor root" EXACT [FMA:53419] synonym: "seventh cranial nerve motor root" EXACT [FMA:53419] is_a: UBERON:0004674 {source="FMA"} ! facial nerve root relationship: develops_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon xref: FMA:53419 ! motor root of facial nerve xref: SCTID:280191009 ! Motor root of facial nerve [Term] id: UBERON:0001700 name: geniculate ganglion def: "The geniculate ganglion is an L-shaped collection of fibers and sensory neurons of the facial nerve located in the facial canal of the head. It receives fibers from the motor, sensory, and parasympathetic components of the facial nerve and sends fibers that will innervate the lacrimal glands, submandibular glands, sublingual glands, tongue, palate, pharynx, external auditory meatus, stapedius, posterior belly of the digastric muscle, stylohyoid muscle, and muscles of facial expression. Sensory and parasympathetic inputs are carried into the geniculate ganglion via the nervus intermedius. Motor fibers are carried via the facial nerve proper. The greater petrosal nerve, which carries sensory fibers as well as preganglionic parasympathetic fibers, emerges from the anterior aspect of the ganglion. The geniculate ganglion is one of several ganglia of the head and neck. Like the others, it is a bilaterally distributed structure, with each side of the face having a geniculate ganglion. [WP,unvetted]." [Wikipedia:Geniculate_ganglion] comment: Editor notes: resolve facial VII vs geniculate (see EHDAA2) subset: uberon_slim subset: vertebrate_core synonym: "geniculate ganglion" RELATED [MA:0001076] synonym: "facial ganglion" RELATED [ZFA:0001291] synonym: "facial VII ganglion" EXACT [MA:0001076] synonym: "ganglion genicularum" EXACT [FMA:53414] synonym: "genicular ganglion" EXACT [FMA:53414] synonym: "ganglion geniculi" RELATED [Wikipedia:Geniculate_ganglion] synonym: "genicular ganglion" EXACT [Wikipedia:Geniculate_ganglion] synonym: "geniculate" BROAD [Wikipedia:Geniculate_ganglion] synonym: "internal genu" RELATED [Wikipedia:Geniculate_ganglion] synonym: "gVII" EXACT [ZFA:0001291] synonym: "ganglion geniculi nervi facialis" RELATED LATIN [Wikipedia:Geniculate_ganglion] xref: EHDAA:5567 ! facial VII ganglion xref: EHDAA:6644 ! facial VII ganglion xref: FMA:53414 ! Geniculate ganglion xref: GAID:718 ! geniculate ganglion xref: VHOG:0000707 ! facial VII ganglion xref: MA:0001076 ! facial VII ganglion xref: TAO:0001291 ! facial ganglion xref: ZFA:0001291 ! facial ganglion xref: ncithesaurus:Geniculate_Ganglion ! Geniculate Ganglion xref: EHDAA2:0000491 ! facial VII ganglion xref: EHDAA2:0004623 ! geniculate ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Gray789.png/200px-Gray789.png xref: EMAPA:16983 ! facial ganglion VII xref: EMAPA:17569 ! facial VII of cranial of ganglion of central nervous system of nervous system of organ system xref: MESH:A08.340.390.380 ! geniculate ganglion xref: EFO:0003669 ! facial ganglion is_a: UBERON:0001800 {source="ncithesaurus"} ! sensory ganglion is_a: UBERON:0001714 {source="MA"} ! cranial ganglion relationship: develops_from UBERON:0005565 {source="ZFA", notes="check for multi-species"} ! facio-acoustic neural crest relationship: develops_from UBERON:0009124 {source="ZFA", source="EHDAA2:0004623"} ! geniculate placode relationship: develops_from UBERON:0010258 {source="EHDAA2:0004623"} ! mesenchyme from rhombencephalic neural crest relationship: develops_from UBERON:0012175 {source="EHDAA2:0000491"} ! acoustico-facial VII-VIII ganglion complex xref: SCTID:279076005 ! Entire geniculate ganglion xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray789.png property_value: homology_notes "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000707", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0017406 [Term] id: UBERON:0005565 name: facio-acoustic neural crest def: "Cranial neural crest that gives rise to the facio-acoustic ganglion." [ZFA:0000762] subset: vertebrate_core synonym: "facio acoustic neural crest" EXACT [ZFA:0000762] xref: ZFA:0000762 ! facio-acoustic neural crest xref: EHDAA2:0000492 ! facio-acoustic neural crest xref: EMAPA:16312 ! facio-acoustic neural crest xref: VHOG:0000268 ! facio-acoustic neural crest xref: EHDAA:658 ! facio-acoustic neural crest is_a: UBERON:0003099 ! cranial neural crest is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: develops_from UBERON:0003849 {source="EHDAA2"} ! mesencephalic neural crest xref: TAO:0000762 ! facio-acoustic neural crest property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000268", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006232 ! facio-acoustic VII-VIII preganglion complex name: facio-acoustic VII-VIII preganglion complex subset: emapa_ehdaa2 xref: EMAPA:16660 ! facio-acoustic VII-VIII preganglion complex xref: RETIRED_EHDAA2:0000496 ! facio-acoustic VII-VIII preganglion complex xref: EHDAA:1477 ! facio-acoustic VII-VIII preganglion complex xref: VHOG:0000715 ! facio-acoustic VII-VIII ganglion complex is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0001714 {source="EHDAA2"} ! cranial ganglion relationship: develops_from UBERON:0005565 ! facio-acoustic neural crest [Term] id: UBERON:0012175 name: acoustico-facial VII-VIII ganglion complex is_a: UBERON:0001714 {source="cjm"} ! cranial ganglion relationship: develops_from UBERON:0003051 {source="EHDAA2"} ! ear vesicle relationship: develops_from UBERON:0006232 {source="cjm"} ! facio-acoustic VII-VIII preganglion complex xref: EHDAA2:0000494 ! acoustico-facial VII-VIII ganglion complex xref: EMAPA:16794 ! facio-acoustic ganglion complex VII-VIII xref: VHOG:0000715 ! facio-acoustic VII-VIII ganglion complex synonym: "facio-acoustic VII-VIII ganglion complex" RELATED [VHOG:0000715] synonym: "facio-acoustic ganglion complex VII-VIII" EXACT [EMAPA:16794] [Term] id: UBERON:0013498 name: vestibulo-cochlear VIII ganglion complex comment: Editor's note: requires verification is_a: UBERON:0001714 {source="cjm"} ! cranial ganglion xref: EMAPA:17570 ! vestibulo-cochlear VIII ganglion complex xref: EHDAA2:0004313 ! vestibular VIII ganglion complex synonym: "vestibular VIII ganglion complex" RELATED [EHDAA2:0004313] synonym: "vestibulocochlear VIII ganglion complex" EXACT [] synonym: "vestibulocochlear ganglion complex" EXACT [] [Term] id: UBERON:0013499 name: glossopharyngeal-vagus IX-X preganglion complex is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0001714 {source="cjm"} ! cranial ganglion xref: EMAPA:16662 ! glossopharyngeal-vagus IX-X preganglion complex [Term] id: UBERON:0013500 name: glossopharyngeal-vagus IX-X ganglion complex is_a: UBERON:0001714 {source="cjm"} ! cranial ganglion relationship: develops_from UBERON:0013499 ! glossopharyngeal-vagus IX-X preganglion complex xref: EMAPA:16796 ! glossopharyngeal-vagus IX-X ganglion complex [Term] id: UBERON:0002827 name: auditory ganglion comment: Editor notes: Consider follow MA naming scheme. // The cell bodies of the cochlear nerve lie within the central aspect of the cochlea and are collectively known as the spiral ganglion. This name reflects the fact that the cell bodies, considered as a unit, have a spiral (or perhaps more accurately, a helical) shape, reflecting the shape of the cochlea. The terms "cochlear nerve fiber" and "spiral ganglion cell" are used, to some degree, interchangeably, although the former may be used to more specifically refer to the central axons of the cochlear nerve. These central axons exit the cochlea at its base, where it forms a nerve trunk. In humans, this aspect of the nerve is roughly one inch in length. It projects centrally to the brainstem, where its fibers synapse with the cell bodies of the cochlear nucleus[Wikipedia:Cochlear_nerve] subset: vertebrate_core synonym: "auditory ganglion" EXACT [ZFA:0000588] synonym: "gVIII" EXACT [ZFA:0000588] synonym: "SAG" BROAD [ZFA:0000588] synonym: "statoacoustic ganglia" EXACT [ZFA:0000588] synonym: "vestibulocochlear VIII ganglion" EXACT [MA:0001084] synonym: "statoacoustic (VIII) ganglion" EXACT [ZFA:0000588] synonym: "acoustico-vestibular VIII ganglion" EXACT [EHDAA2:0002196] synonym: "acoustic ganglion VIII" EXACT [EMAPA:16982] synonym: "ganglion VIII" EXACT [] xref: NIF_GrossAnatomy:birnlex_2564 ! Auditory ganglion xref: ZFA:0000588 ! statoacoustic (VIII) ganglion xref: MA:0001084 ! vestibulocochlear VIII ganglion xref: VHOG:0000696 ! vestibulocochlear VIII ganglion xref: EHDAA2:0002196 ! acoustico-vestibular VIII ganglion xref: EHDAA:5569 ! vestibulocochlear VIII ganglion xref: EHDAA:6653 ! vestibulocochlear VIII ganglion xref: EMAPA:17571 ! vestibulocochlear VIII of cranial of ganglion of central nervous system of nervous system of organ system xref: EFO:0003543 ! statoacoustic (VIII) ganglion xref: EMAPA:16982 ! acoustic ganglion VIII is_a: UBERON:0001714 {source="ZFA"} ! cranial ganglion relationship: develops_from UBERON:0003249 {source="NBK53175"} ! epithelium of otic placode relationship: develops_from UBERON:0005565 {source="ZFA"} ! facio-acoustic neural crest relationship: develops_from UBERON:0012175 {source="EHDAA2"} ! acoustico-facial VII-VIII ganglion complex relationship: part_of UBERON:0002105 {source="ZFA"} ! vestibulo-auditory system xref: XAO:0004142 ! vestibulocochlear ganglion xref: TAO:0000588 ! statoacoustic (VIII) ganglion property_value: external_definition "The sensory ganglion of the ear. (See Anatomical Atlas entry for statoacoustic ganglion by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000588", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "acoustic ganglion" RELATED [VHOG:0000696] synonym: "statoacoustic VIII ganglion" RELATED [VHOG:0000696] property_value: homology_notes " (During the development of the inner ear in a vertebrate embryo) As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII.[well established][VHOG]" xsd:string {external_class="VHOG:0000696", ontology="VHOG", source="PMID:21452441 Park BY\, Saint-Jeannet JP\, Induction and Segregation of the Vertebrate Cranial Placodes. Developmental Biology (2010)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000395 name: cochlear ganglion def: "group of nerve cells that serve the sense of hearing by sending a representation of sound from the cochlea to the brain. The cell bodies of the spiral ganglion neurons are found in the spiral structure of the cochlea[WP]. the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)[MP]." [Wikipedia:Spiral_ganglion, MP:0002855] comment: Editor notes: in BTO this is part of the cochlear modiolus, but this leads to the CG being in both the nervous and skeletal systems synonym: "Corti's ganglion" EXACT [FMA:53445] synonym: "ganglion of Corti" EXACT [FMA:53445] synonym: "spiral ganglion" EXACT [FMA:53445] synonym: "vestibulocochlear VIII ganglion cochlear component" EXACT [MA:0001085] synonym: "ganglion cochlearis" RELATED [BTO:0001688] synonym: "ganglion spirale cochleae" RELATED [BTO:0001688] synonym: "spiral ganglion of cochlea" RELATED [BTO:0001688] xref: BTO:0001688 xref: FMA:53445 ! Cochlear ganglion xref: MA:0001085 ! vestibulocochlear VIII ganglion cochlear component xref: GAID:722 ! spiral ganglion xref: VHOG:0001183 ! vestibulocochlear VIII ganglion cochlear component xref: EHDAA2:0002198 ! vestibulocochlear VIII ganglion cochlear component xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Gray903.png/200px-Gray903.png xref: MESH:A08.340.390.800 ! spiral ganglion is_a: UBERON:0001714 {source="FMA"} ! cranial ganglion relationship: located_in UBERON:0006723 {source="BTO-modified"} ! cochlear modiolus relationship: part_of UBERON:0002827 {source="MA"} ! auditory ganglion xref: SCTID:368955007 ! Entire spiral ganglion synonym: "ganglion spirale" RELATED LATIN [Wikipedia:Spiral_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray903.png [Term] id: UBERON:0002824 name: vestibular ganglion def: "The vestibular nerve ganglion (also called Scarpa's ganglion) is the ganglion of the vestibular nerve. It contains the cell bodies of the bipolar primary afferent neurons whose peripheral processes form synaptic contact with hair cells of the vestibular sensory end organs[WP,unvetted]." [Wikipedia:Scarpa%27s_ganglion] subset: uberon_slim synonym: "Scarpa's ganglion" EXACT [FMA:53435] synonym: "vestibulocochlear VIII ganglion vestibular component" EXACT [MA:0001086] synonym: "vestibulocochlear component" EXACT [] xref: FMA:53435 ! Vestibular ganglion xref: NIF_GrossAnatomy:birnlex_2549 ! Vestibular ganglion xref: ncithesaurus:Vestibular_Ganglion ! Vestibular Ganglion xref: MA:0001086 ! vestibulocochlear VIII ganglion vestibular component xref: VHOG:0000682 ! vestibulocochlear VIII ganglion vestibular component xref: EMAPA:17573 ! vestibular component of vestibulocochlear VIII of cranial of ganglion of central nervous system of nervous system of organ system xref: RETIRED_EHDAA2:0002199 ! vestibulocochlear VIII ganglion vestibular component is_a: UBERON:0001800 {source="ncithesaurus"} ! sensory ganglion is_a: UBERON:0001714 {source="FMA"} ! cranial ganglion relationship: part_of UBERON:0002827 {source="MA"} ! auditory ganglion xref: SCTID:244450009 ! Entire vestibular ganglion xref: UMLS:C0036286 [Term] id: UBERON:0001701 name: glossopharyngeal ganglion def: "the group of neuron cell bodies associated with the ninth cranial nerve." [MP:0001096] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "ganglion of glosspharyngeal nerve" EXACT [] synonym: "gIX" RELATED [] synonym: "petrosal ganglion" NARROW [ZFA:0001301] synonym: "glossopharyngeal IX ganglion" EXACT [MA:0001077] xref: FMA:53471 ! Glossopharyngeal ganglion xref: TAO:0001301 ! glossopharyngeal ganglion xref: ZFA:0001301 ! glossopharyngeal ganglion xref: MA:0001077 ! glossopharyngeal IX ganglion xref: EHDAA2:0000710 ! glossopharyngeal IX ganglion xref: VHOG:0000702 ! glossopharyngeal IX ganglion xref: EMAPA:16795 ! glossopharyngeal IX of cranial of ganglion of central nervous system of nervous system of organ system xref: EHDAA:2838 ! glossopharyngeal IX ganglion is_a: UBERON:0001714 {source="FMA"} ! ganglion of cranial nerve is_a: UBERON:0001714 {source="MA"} ! cranial ganglion is_a: UBERON:0009127 {source="ZFA"} ! epibranchial ganglion relationship: develops_from UBERON:0009125 {source="ZFA", source="EHDAA2"} ! petrosal placode relationship: develops_from UBERON:0005491 {source="ZFA", source="EHDAA2"} ! glossopharyngeal neural crest xref: SCTID:244451008 ! Glossopharyngeal ganglion property_value: homology_notes "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000702", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005360 name: inferior glossopharyngeal IX ganglion def: "the lower group of sensory neuron cell bodies associated with the glossopharyngeal nerve[MP]. It is situated in a depression in the lower border of the petrous portion of the temporal bone[WP]." [MP:0001084, Wikipedia:Inferior_ganglion_of_glossopharyngeal_nerve] comment: We follow FMA and VHOG in making the relation subclass synonym: "inferior glossopharyngeal ganglion" EXACT [FMA:53475] synonym: "ganglion inferius (nervus glossopharygeus)" EXACT [FMA:53475] synonym: "ganglion of andersch" EXACT [FMA:53475] synonym: "glossopharyngeal nerve inferior ganglion" EXACT [FMA:53475] synonym: "glossopharyngeal nerve petrous ganglion" EXACT [FMA:53475] synonym: "inferior ganglion of glossopharyngeal nerve" EXACT [FMA:53475] synonym: "ninth cranial nerve inferior ganglion" EXACT [FMA:53475] synonym: "extracraniale ganglion" EXACT [MP:0001084] synonym: "inferior glossopharyngeal ganglion of the glossopharyngeal (IX) nerve" EXACT [MP:0001084] synonym: "petrosal ganglion" RELATED [MP:0001084, http://www.merriam-webster.com/medical/petrosal%20ganglion] synonym: "petrosal ganglion" RELATED [MP:0001084] synonym: "petrous ganglion" RELATED [Wikipedia:Inferior_ganglion_of_glossopharyngeal_nerve, http://www.merriam-webster.com/medical/petrous%20ganglion, http://en.wikipedia.org/wiki/File:Gray791.png] synonym: "ganglion inferius nervus glossopharyngei" EXACT LATIN [FMA:TA, FMA:53475] xref: MA:0001078 ! inferior glossopharyngeal IX ganglion xref: FMA:53475 ! Inferior glossopharyngeal ganglion xref: EHDAA2:0000711 ! glossopharyngeal IX ganglion inferior ganglion xref: VHOG:0000743 ! glossopharyngeal IX inferior ganglion is_a: UBERON:0001701 {source="FMA"} ! glossopharyngeal ganglion xref: SCTID:66031007 ! Glossopharyngeal nerve inferior ganglion synonym: "ganglion inferius nervi glossopharyngei, ganglion petrosum" RELATED LATIN [Wikipedia:Inferior_ganglion_of_glossopharyngeal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png synonym: "glossopharyngeal IX inferior ganglion" RELATED [VHOG:0000743] [Term] id: UBERON:0005361 name: superior glossopharyngeal IX ganglion def: "the upper ganglion of the glossopharyngeal nerve[MP]. is situated in the upper part of the groove in which the glossopharyngeal nerve is lodged during its passage through the jugular foramen. It is very small, and is usually regarded as a detached portion of the inferior ganglion" [MP:0001097, Wikipedia:Superior_ganglion_of_glossopharyngeal_nerve] comment: Synonym modified from WP original synonym: "superior petrosal ganglion" RELATED [Wikipedia:Superior_ganglion_of_glossopharyngeal_nerve] synonym: "intracranial ganglion" EXACT [MP:0001097] synonym: "jugular ganglion" RELATED [MP:0001097] synonym: "superior glossopharyngeal ganglia" EXACT [MP:0001097] synonym: "superior glossopharyngeal ganglion of the glossopharyngeal (IX) nerve" EXACT [MP:0001097] synonym: "superior glossopharyngeal ganglia" EXACT [MP:0001097] synonym: "Ehrenritter's ganglion" EXACT [FMA:53474] synonym: "ganglion superius (nervus glossopharyngeus)" EXACT [FMA:53474] synonym: "glossopharyngeal nerve jugular ganglion" EXACT [FMA:53474] synonym: "glossopharyngeal nerve superior ganglion" EXACT [FMA:53474] synonym: "ninth cranial nerve superior ganglion" EXACT [FMA:53474] synonym: "superior ganglion of glossopharyngeal nerve" EXACT [FMA:53474] synonym: "ganglion superius nervus glossopharyngei" EXACT LATIN [FMA:TA, FMA:53474] xref: MA:0001079 ! superior glossopharyngeal IX ganglion xref: FMA:53474 ! Superior glossopharyngeal ganglion xref: EHDAA2:0000712 ! glossopharyngeal IX ganglion superior ganglion xref: VHOG:0000744 ! glossopharyngeal IX superior ganglion xref: EHDAA:2842 ! superior ganglion of glossopharyngeal IX ganglion is_a: UBERON:0001701 {source="FMA"} ! glossopharyngeal ganglion xref: SCTID:280362000 ! Intracranial ganglion synonym: "ganglion superius nervi glossopharyngei" RELATED LATIN [Wikipedia:Superior_ganglion_of_glossopharyngeal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png synonym: "superior glossopharyngeal ganglion" EXACT [FMA:53474] synonym: "glossopharyngeal IX superior ganglion" RELATED [VHOG:0000744] [Term] id: UBERON:0001702 ! eyelash name: eyelash def: "An eyelash or simply lash is one of the hairs that grow at the edge of the eyelid. Eyelashes protect the eye from debris and perform some of the same function as whiskers do on a cat or a mouse in the sense that they are sensitive to being touched, thus providing a warning that an object is near the eye (which is then closed reflexively). The greek word for eyelash is \"blepharis\". This word is often used as a root in biological terms" [Wikipedia:Eyelash] subset: uberon_slim synonym: "cilia" RELATED LATIN [Wikipedia:Eyelash] synonym: "hair of eyelid" RELATED [] xref: FMA:53669 ! Eyelash xref: GAID:73 ! eyelash xref: MA:0002702 ! eyelash xref: OpenCyc:Mx4rvVi41pwpEbGdrcN5Y29ycA xref: ncithesaurus:Eyelash ! Eyelash xref: OpenCyc:Mx4rvVi41pwpEbGdrcN5Y29ycA ! eyelash xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/96/N2_Human_eye.jpg/200px-N2_Human_eye.jpg xref: MESH:A01.456.505.420.504.421 ! eyelash is_a: UBERON:0001037 ! strand of hair relationship: attaches_to UBERON:0001711 ! eyelid xref: SCTID:244201001 ! Entire eyelash xref: http://upload.wikimedia.org/wikipedia/commons/9/96/N2_Human_eye.jpg xref: UMLS:C0015422 [Term] id: UBERON:0004765 ! skeletal element name: skeletal element def: "Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles." [UBERON:cjm] comment: TODO - add more general class for other kinds of mineralized tissue subset: uberon_slim xref: TAO:0001890 ! skeletal element xref: galen:SkeletalStructure xref: ZFA:0005494 ! skeletal element xref: VSAO:0000128 ! skeletal element xref: AAO:0011129 ! skeletal element is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001434 {source="VSAO"} ! skeletal system xref: XAO:0004012 ! skeletal element subset: organ_slim property_value: external_definition "Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001890", date_retrieved="2012-08-14", source="TAO:VSAO_workshop"} property_value: external_definition "Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000128", date_retrieved="2012-08-14", source="PSPUB:0000170"} [Term] id: UBERON:0000032 name: obsolete cranial structure comment: obsoleted as it was a grouping class that served no purpose is_obsolete: true [Term] id: UBERON:0010323 ! cranial skeletal system name: cranial skeletal system synonym: "cranial skeleton" NARROW [] def: "Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [VSAO:0000049] comment: Note that the cranial skeleton includes the pharyngeal arch skeleton. It is thus more inclusive that the cranium itself, and extends beyond the head in tetrapods. The AAO class called 'skull' belongs here, as it includes the whole splanchnocranium. Editor notes: we use 'cranial skeletal system', so that we can include the skull, which has joints/sutures as parts (recall, we follow FMA in distinguishing between the skeleton and skeletal system - only the latter includes joints) synonym: "osteocranium" NARROW [] synonym: "cranium" RELATED INCONSISTENT [ZFA:0000737] is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0011137 ! axial skeletal system xref: VSAO:0000049 ! cranial skeleton xref: TAO:0000737 ! cranium xref: ZFA:0000737 ! cranium xref: AAO:0000109 ! cranium xref: XAO:0003075 ! cranium xref: AAO:0010185 ! skull xref: AAO:0000971 ! cranial property_value: external_definition "Bony structure that encases the central nervous system and the primary sense organs of sight, olfaction, hearing, and equilibrium.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000109", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Skeletal system which is part of the skull, including the splanchnocranium, chondrocranium, and dermatocranium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000737", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0011159 ! primary subdivision of cranial skeletal system name: primary subdivision of cranial skeletal system subset: non_informative is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: part_of UBERON:0010323 ! cranial skeletal system [Term] id: UBERON:0003129 name: skull def: "Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]." [Wikipedia:Skull, http://sourceforge.net/tracker/?func=detail&aid=2962656&group_id=76834&atid=1205376, PMID:11523816] comment: In FMA the skull is divided into orbit, neurocranium (8 parts), viscerocranium (26 parts). Here we have a separate overlapping division into cranium and mandible. // A skull that is missing a mandible is only a cranium; this is the source of a very commonly made error in terminology. Those animals having skulls are called craniates[WP]. Editor/AO notes: in many ontologies, the structure called the cranium is inclusive of the mandible/lower jaw skeleton subset: uberon_slim synonym: "cranial skeleton" RELATED [] synonym: "skeletal system of head" RELATED [] xref: FMA:46565 ! Skull xref: BTO:0001295 ! cranium xref: ncithesaurus:Skull ! Skull xref: GAID:82 ! skull xref: galen:Skull ! skull xref: OpenCyc:Mx4rvVjOsZwpEbGdrcN5Y29ycA ! skull xref: MESH:A02.835.232.781 ! skull xref: EHDAA2:0000325 ! cranium xref: EMAPA:17680 ! cranium xref: SCTID:110530005 ! Cranial and facial bones xref: WikipediaCategory:Skull is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: part_of UBERON:0010323 ! cranial skeletal system relationship: part_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: has_part UBERON:0003278 ! skeleton of lower jaw relationship: has_part UBERON:0003128 ! cranium xref: UMLS:C0037303 [Term] id: UBERON:0003128 name: cranium def: "Upper portion of the skull that excludes the mandible (when present in the organism)." [Wikipedia:Cranium_(anatomy)] comment: The term cranium can be ambiguous, in that it can refer to the neurocranium, or the neurocranium and the Facial skeleton[WP]. AO notes: the inclusion of the FMA class here is probably not quite correct, as this class includes as parts sutures, whereas this is not part of the bones of the cranium subset: uberon_slim subset: vertebrate_core synonym: "upper part of skull" EXACT [] synonym: "skull minus mandible" EXACT [] synonym: "epicranial plate" RELATED [] synonym: "skeletal system of head" RELATED [] synonym: "bones of cranium" EXACT [FMA:71325] synonym: "calvarium" RELATED [BTO:0001328] xref: EFO:0000831 ! cranium xref: EHDAA:6029 ! cranium xref: VHOG:0000334 ! cranium xref: MA:0000316 ! cranium xref: MAT:0000340 ! cranium xref: MIAA:0000340 ! cranium xref: OpenCyc:Mx4rvVlEyJwpEbGdrcN5Y29ycA xref: FMA:71325 ! Set of bones of cranium xref: OpenCyc:Mx4rvVlEyJwpEbGdrcN5Y29ycA ! cranium xref: BTO:0001328 ! calvarium is_a: UBERON:0000075 {source="FMA-inferred"} ! subdivision of skeletal system relationship: part_of UBERON:0003129 ! skull relationship: spatially_disjoint_from UBERON:0003278 ! skeleton of lower jaw synonym: "ossa cranii" EXACT LATIN [FMA:TA, FMA:71325] xref: SCTID:181889008 ! Entire cranium synonym: "set of bones of cranium" EXACT [FMA:71325] property_value: has_relational_adjective "cranial" xsd:string [Term] id: UBERON:0011158 name: primary subdivision of skull def: "The skull can be divided into two: the neurocranium and the facial skeleton" [] synonym: "skull subdivision" EXACT [FMA:54964] synonym: "subdivision of skull" EXACT [FMA:54964] subset: non_informative is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: part_of UBERON:0003129 ! skull xref: FMA:54964 ! subdivision of skull [Term] id: UBERON:0004766 name: cranial bone def: "A bone that is part of a cranium." [UBERON:automatic] comment: Note that here cranium = skull - mandible synonym: "cranium bone" EXACT [UBERON:automatic] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0003128 ! cranium xref: SCTID:181792001 ! Entire cranial bone [Term] id: UBERON:0000075 ! subdivision of skeletal system alt_id: UBERON:0010322 name: subdivision of skeletal system def: "Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism." [UBERON:cjm, UBERONREF:0000003] synonym: "skeletal system part" RELATED [] synonym: "skeletal system subdivision" EXACT [FMA:85544] subset: non_informative xref: FMA:85544 ! Subdivision of skeletal system xref: galen:ComplexSkeletalStructure is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0001434 ! skeletal system xref: ncithesaurus:Skeletal_System_Part ! Skeletal System Part xref: SCTID:118966000 ! Skeletal system subdivision xref: UMLS:C1519343 [Term] id: UBERON:0010912 ! subdivision of skeleton name: subdivision of skeleton def: "Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints." [UBERON:cjm, UBERONREF:0000003] comment: AO notes: VSAO def logically wrong subset: non_informative is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0004288 {source="VSAO"} ! skeleton relationship: part_of UBERON:0000075 {source="UBERONREF:0000003"} ! subdivision of skeletal system synonym: "skeletal subdivision" EXACT [VSAO:0000042] synonym: "subdivision of skeleton (in vivo)" RELATED [FMA:23879] xref: FMA:23879 ! subdivision of skeleton (in vivo) xref: VSAO:0000042 ! skeletal subdivision xref: SCTID:129140006 ! Bony skeleton subdivision property_value: external_definition "Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000042", date_retrieved="2012-08-14", source="VSAO:curator"} [Term] id: UBERON:0010324 name: obsolete craniofacial region is_obsolete: true consider: UBERON:0001456 ! face xref: VSAO:0000083 ! craniofacial region [Term] id: UBERON:0010325 ! craniofacial skeleton name: obsolete craniofacial skeleton def: "Cranial skeleton derived from neural crest cells." [VSAO:0000082] synonym: "Cranio-facial skeleton" EXACT [VSAO:curator] is_obsolete: true consider: UBERON:0011156 ! facial skeleton xref: VSAO:0000082 ! craniofacial skeleton [Term] id: UBERON:0004339 name: vault of skull def: "Upper part of skull, consisting of parietals, frontals, post-parietals, and in some species the squamosal and a portion of the alisphenoid" [PMID:11523816, MP:0000076, Wikipedia:Calvaria_(skull)] comment: Editor notes: We follow PMID:11523816 (Morriss-Kay) in defining the components of the skull vault. Note that there is a conflict with Kardong; e.g. in fig 7.10, Kardong places the squamosal in the temporal series. We cannot place the vault as entirely part of the dermatocranium as it has a small splanchnocranium contribution and a sclerotomal contribution. Terminology notes. we include calvarium as a synonym, but Gray's Anatomy's list includes the Ethmoid and Sphenoid bone in the Calvaria. Some books (and HPO) state that calvaria consists of just the frontal bone, parietal bone, temporal bone, and occipital bone. Note vault may not be precisely equivalent to calvaria synonym: "calvarium" RELATED [] synonym: "calvaria" RELATED PLURAL [ZFA:0005606] synonym: "skullcap" RELATED [ZFA:0005606] synonym: "calva" EXACT [FMA:52800] synonym: "skull vault" EXACT [] xref: FMA:52800 ! calvaria xref: EMAPA:18016 ! vault of skull xref: EHDAA2:0002167 ! vault of skull xref: EHDAA:9538 ! vault of skull xref: VHOG:0000331 ! vault of skull is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0001703 ! neurocranium relationship: overlaps UBERON:0003113 {notes="small pharyngeal arch and sclerotomal contribution"} ! dermatocranium xref: SCTID:140592008 ! Entire calvaria xref: ZFA:0005606 ! cranial vault xref: ncithesaurus:Skullcap ! skullcap property_value: homology_notes "The earliest tetrapods arose from rhipidistian ancestors and retained many of their skull features, including most of the bones of the dermatocranium.[well established][VHOG]" xsd:string {external_class="VHOG:0000331", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.256", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0205950 [Term] id: UBERON:0002517 ! basicranium name: basicranium def: "The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof." [Wikipedia:Base_of_skull] comment: The skull base is formed from a series of cartilages either side of, and rostral to, the notochord, whose tip lies just caudal to the pituitary gland. It is closely associated with the sensory capsules, which partially or completely sur- round the olfactory epithelium, the eye, and the inner ear[PMID:11523816] subset: uberon_slim synonym: "skull base" EXACT [] synonym: "base of skull" EXACT [] synonym: "cranial base" RELATED [MA:0002840] xref: FMA:52801 ! Basicranium xref: MA:0002840 ! basicranium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/81/Gray193.png/200px-Gray193.png xref: MESH:A01.456.830 ! skull base is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium synonym: "basis cranii" EXACT LATIN [FMA:TA, FMA:52801] xref: ncithesaurus:Base_of_the_Skull ! Base of the Skull xref: SCTID:181890004 ! Entire base of skull synonym: "basis cranii" RELATED LATIN [Wikipedia:Base_of_skull] xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png property_value: has_relational_adjective "basicranial" xsd:string xref: UMLS:C0149543 [Term] id: UBERON:0001703 name: neurocranium def: "Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof." [Wikipedia:Neuroranium, ZFA:0001580, TAO:MAH, PMID:11523816] comment: Development notes: The cartilaginous parts of the neurocranium undergo endochondral ossification in most species; ossification has been lost in cartilaginous fishes, but the cartilaginous condition of the skull of lampreys is considered to be primitive (Kardong, 1995)[PMID:11523816]. The neurocranium arises from paraxial mesoderm in the head (first five somites and the unsegmented somitomeres rostral to the first somite) and from ectoderm via the neural crest. In Chondrichthyes and other cartilaginous vertebrates this portion of the cranium does not ossify; it is not replaced via endochondral ossification[WP]. Composition notes: It includes the following bones: Ethmoid bone, Frontal bone, Occipital bone, Parietal bone, Sphenoid bone, Temporal bone. The term cranium can be ambiguous, in that it can refer to the neurocranium, or the neurocranium and the Facial skeleton[WP] AO notes: It seems MA uses 'neurocranium' as a synonym for chondrocranium. Note there are currently some structures part of both viscero and neurocranium - ethmoid, zyogomatic, ... subset: uberon_slim subset: vertebrate_core synonym: "brain box" EXACT [] synonym: "brain case" RELATED [ZFA:0001580] synonym: "braincase" RELATED [ZFA:0001580] synonym: "brain pan" RELATED [http://www.thefreedictionary.com/braincase] xref: MA:0000317 ! chondrocranium xref: FMA:53672 ! Neurocranium xref: TAO:0001580 ! neurocranium xref: ZFA:0001580 ! neurocranium xref: XAO:0003170 ! neurocranium xref: EHDAA2:0000243 ! chondrocranium (also: UBERON:0002241 'chondrocranium') xref: AAO:0010153 ! neurocranium (also: UBERON:0004761 'cartilaginous neurocranium') is_a: UBERON:0011158 {source="FMA"} ! subdivision of skull relationship: part_of UBERON:0003128 ! cranium relationship: develops_from UBERON:0004761 ! cartilaginous neurocranium relationship: encloses UBERON:0000955 ! brain xref: SCTID:361731002 ! Entire neurocranium property_value: external_definition "Anatomical cluster that consists of the cartilages and bones that surround the brain.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001580", date_retrieved="2012-08-14", source="TAO:MAH"} property_value: has_relational_adjective "neurocranial" xsd:string [Term] id: UBERON:0002241 name: chondrocranium def: "Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]." [http://medical-dictionary.thefreedictionary.com/chondrocranium, Wikipedia:Chondrocranium] comment: Editor/AO notes: we follow the standard evolutionary classification and treat this as endoskeletal. This means what MA calls 'chondrocranium' must in fact be neurocranium, as it includes parts of the dermatocranium (e.g. frontal, parietal). Taxon notes: covers the brain dorsally in chondrichthyans subset: vertebrate_core synonym: "neurocranium" RELATED INCONSISTENT [MA:0000317] synonym: "calvarium" RELATED [MA:0000317] xref: VHOG:0000288 ! chondrocranium xref: TAO:0001424 ! chondrocranium xref: ZFA:0001424 ! chondrocranium xref: EHDAA2:0000243 ! chondrocranium (also: UBERON:0001703 'neurocranium') xref: EMAPA:17681 ! chondrocranium is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system relationship: overlaps UBERON:0001703 ! neurocranium xref: AAO:0010169 ! chondrocranium property_value: external_definition "Anatomical cluster that is part of the cranium and composed of cartilage and cartilage replacement bones.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010169", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Anatomical cluster that is part of the cranium and composed of cartilage and cartilage replacement bones.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001424", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "chondrocranial" xsd:string [Term] id: UBERON:0003932 name: cartilage element of chondrocranium def: "A cartilage element of chondrocranium. Example: neurocranial trabecula." [UBERON:cjm] synonym: "cartilaginous element of chondrocranium" EXACT [OBOL:accepted] synonym: "cartilage of chondrocranium" EXACT [OBOL:accepted] synonym: "neurocranium cartilage" EXACT [ZFA:0001461] synonym: "chondrocranium cartilage" EXACT [ZFA:0001461] xref: ZFA:0001461 ! chondrocranium cartilage xref: EFO:0003690 ! chondrocranium cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0002241 ! chondrocranium xref: TAO:0001461 ! chondrocranium cartilage [Term] id: UBERON:0004761 ! cartilaginous neurocranium name: cartilaginous neurocranium def: "the primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]." [Wikipedia:Chondrocranium] comment: note that in contrast to chondrocranium, this structure is entirely cartiliginous. In Chondricthyes this is the same as the neurocranium. FMA:76621 is an undefined fetal structure, so we assume the correct placement is here. Note that this is distinct from MA:0000317 which is the uberon:neurocranium (the part of the cranium that encloses the brain) synonym: "embryonic chondocranium" RELATED [] synonym: "chondocranium" RELATED [Wikipedia:Chondrocranium] synonym: "neurocranium" RELATED SENSU [] synonym: "cartilaginous skull" RELATED [] synonym: "cartilaginous chondocranium" EXACT [] synonym: "cartiligionous skeletal structure of skull" EXACT [] xref: AAO:0000094 ! chondrocranium * cartilage xref: AAO:0010153 ! neurocranium (also: UBERON:0001703 'neurocranium') xref: SCTID:155540009 ! fetal chondrocranium xref: EHDAA:6031 ! chondrocranium xref: FMA:76621 ! Chondrocranium xref: XAO:0003059 ! chondrocranium xref: ncithesaurus:Chondrocranium ! Chondrocranium * embryonic is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: develops_from UBERON:0009617 {source="PMC1571569"} ! head paraxial mesoderm relationship: has_part UBERON:0002418 ! cartilage tissue xref: UMLS:C1516496 [Term] id: UBERON:0011156 ! facial skeleton name: facial skeleton def: "Subdivision of skull that consists of the facial bones." [MP:0005274, UBERON:cjm, Wikipedia:Facial_skeleton, http://www.bartleby.com/107/37.html] synonym: "facial skeleton" EXACT [FMA:53673] synonym: "viscerocranium" RELATED INCONSISTENT [MA:0000318] synonym: "facial bone" RELATED [MA:0000318] synonym: "ossa faciei" RELATED LATIN [Wikipedia:Facial_skeleton] synonym: "ossa facialia" RELATED LATIN [Wikipedia:Facial_skeleton] is_a: UBERON:0011158 {source="FMA"} ! subdivision of skull relationship: part_of UBERON:0001456 {source="FMA"} ! face relationship: develops_from UBERON:0002342 {source="PMID:11523816"} ! neural crest xref: FMA:53673 ! viscerocranium xref: MA:0000318 ! viscerocranium xref: EMAPA:18022 ! viscerocranium xref: EHDAA:8361 ! viscerocranium xref: EHDAA2:0002206 ! viscerocranium xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg [Term] id: UBERON:0001704 name: obsolete viscerocranium def: "." [Wikipedia:Facial_skeleton] comment: This class was made obsolete as it conflated the facial skeleton with the splanchnocranium. The facial skeleton includes: * Inferior nasal concha * Lacrimal bone * Mandible * Maxilla * Nasal bone * Palatine bone * Vomer * Zygomatic bone. The hyoid is sometimes included, and sometimes excluded (FMA includes it) (See also notes for ethmoid bone). The splanchoncranium is the endoskeleton derived from pharyngeal arches. is_obsolete: true consider: UBERON:0011156 ! facial skeleton consider: UBERON:0008895 ! pharyngeal arch skeleton [Term] id: UBERON:0008895 ! splanchnocranium name: splanchnocranium def: "Subdivision of endoskeleton derived from pharyngeal arches" [UBERON:cjm, Wikipedia:Facial_skeleton, ISBN10:0073040584] comment: AO notes: VSAO labels this term 'pharyngeal arch' (2012-06-01) - however, it clearly means pharyngeal arch skeleton. Editor/AO notes: many sources define this as the part of the endoskeletal that is from pharyngeal arches - this would make it part-disjoint from dermatocranium. However, there are many bones in AOs that have part-paths to both synonym: "viscerocranium" EXACT INCONSISTENT [Wikipedia:Viscerocranium, VHOG:0000315, ZFA:0001216] synonym: "pharyngeal arch" RELATED INCONSISTENT [VSAO:0000149] synonym: "branchial arch skeleton" RELATED [] synonym: "gill arch skeleton" RELATED [] synonym: "pharyngeal arch skeleton" RELATED [ZFA:0001216] synonym: "pharyngeal skeleton" RELATED [ZFA:0001216] synonym: "visceral skeleton" RELATED [UBERONREF:0000007] is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system relationship: develops_from UBERON:0002539 ! pharyngeal arch relationship: has_developmental_contribution_from UBERON:0003099 {source="Grays", source="PMID:11237469", notes="redundant"} ! cranial neural crest relationship: overlaps UBERON:0011156 ! facial skeleton disjoint_from: UBERON:0011156 ! facial skeleton xref: VSAO:0000149 ! pharyngeal arch xref: AAO:0010157 ! splanchnocranium xref: TAO:0001216 ! splanchnocranium xref: VHOG:0000315 ! viscerocranium xref: ZFA:0001216 ! splanchnocranium xref: XAO:0003176 ! splanchnocranium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Illu_facial_bones.jpg/200px-Illu_facial_bones.jpg property_value: external_definition "Anatomical cluster that is part of the cranium and consists of the jaws, hyoid, and branchial arches.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010157", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Anatomical cluster that is part of the cranium and consists of the jaws, hyoid and branchial arches.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001216", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "The part of the skull derived from the embryonic pharyngeal arches. [Biology_Online][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000315", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The skull of ancestral tetrapods has the three basic components that we have been considering: (1) chondrocranium, (2) splanchnocranium, and (3) dermatocranium (reference 1); Each part of the skull arises from a separate phylogenetic source. The most ancient part is the splanchnocranium (visceral cranium), which first arose to support pharyngeal slits in protochordates (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000315", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.242\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.235", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0011004 name: pharyngeal arch cartilage synonym: "pharyngeal arch cartilages" EXACT PLURAL [ZFA:0001460] synonym: "splanchnocranium cartilage" EXACT [ZFA:0001460] is_a: UBERON:0003933 {source="ZFA"} ! cranial cartilage relationship: part_of UBERON:0008895 {source="ZFA"} ! splanchnocranium intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0008895 ! splanchnocranium xref: ZFA:0001460 ! pharyngeal arch cartilage xref: TAO:0001460 ! pharyngeal arch cartilage xref: EFO:0003689 ! pharyngeal arch cartilage def: "A cartilage element that is part of a splanchnocranium." [OBOL:automatic] [Term] id: UBERON:0009119 ! branchial basket name: branchial basket def: "the network-like cartilaginous skeleton of the gill region of Petromyzontiformes and Holocephali" [http://www.briancoad.com/dictionary/DicPics/branchial%20basket.htm] comment: May also be present in amphioxus. Editor notes: developmental relationship needs to be changed if the scope is broadened, as NC is vertebrate-specific synonym: "gill basket" EXACT [http://www.briancoad.com/dictionary/DicPics/branchial%20basket.htm] xref: http://dev.duit.uwa.edu.au/zoology/media/lamp/E19.jpg is_a: UBERON:0010912 ! subdivision of skeleton relationship: has_part UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0001042 ! chordate pharynx relationship: develops_from UBERON:0002342 {source="PMID:19924811"} ! neural crest subset: cyclostome_subset [Term] id: UBERON:0011164 ! neurocranium bone name: neurocranium bone def: "A bone that is part of a neurocranium [Automatically generated definition]." [OBOL:automatic] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001703 ! neurocranium xref: MA:0001478 ! chondrocranium bone xref: SCTID:120229002 ! Entire bone of neurocranium synonym: "chondrocranium bone" EXACT [MA:0001478] [Term] id: UBERON:0003465 name: obsolete chondrocranium bone def: "A bone that is part of a chondrocranium [Automatically generated definition]." [OBOL:accepted] alt_id: UBERON:0004762 comment: Made obsolete because it conflated neuro and chondro-cranium; also ZFA:0001544 equivalent was made obsolete. is_obsolete: true consider: UBERON:0011164 ! neurocranium bone xref: ZFA:0001544 [Term] id: UBERON:0003113 name: dermatocranium def: "Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]." [Wikipedia:Skull_roof, ZFA:0000863] comment: Editor notes: wikipedia treats skull roof and dermatocranium as synonymous, but some sources treat the roof as being part of the dermatocranium - see UBERONREF:0000007 synonym: "dermal part of skull" RELATED [] synonym: "dermal bone cranium" RELATED [ZFA:0000863] synonym: "skull roof" RELATED [Wikipedia:Skull_roof] synonym: "roof of skull" RELATED [Wikipedia:Skull_roof] synonym: "roofing bones of the skull" RELATED [Wikipedia:Skull_roof] synonym: "exocranium" EXACT [UBERONREF:0000007] xref: XAO:0003169 ! dermatocranium xref: ZFA:0000863 ! dermatocranium is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system relationship: part_of UBERON:0010323 {source="ZFA"} ! cranial skeletal system relationship: never_in_taxon NCBITaxon:7777 {source="Kardong"} ! Chondrichthyes xref: AAO:0010154 ! dermatocranium xref: TAO:0000863 ! dermatocranium xref: VHOG:0001665 ! dermatocranium property_value: external_definition "Anatomical cluster that is part of the cranium which consists of dermally derived bones.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010154", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Anatomical cluster that is part of the cranium and composed of dermally derived bones.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000863", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "dendrocranium" EXACT [TAO:0000863] [Term] id: UBERON:0001714 name: cranial ganglion alt_id: UBERON:0003213 def: "Ganglion of a cranial nerve[cjm]." [Wikipedia:Cranial_nerve_ganglion] comment: Editor note: split out MA ter,. Note the MA term is part of the CNS. This needs to be checked w.r.t relationship between ganglia and the PNS, as the PNS and CNS are spatially disjoint. also meaning of MA term is not clear (appears to be union of nerve and ganglion, but MA 'cranial nerve' is unconnected) subset: uberon_slim subset: vertebrate_core synonym: "cranial ganglion/nerve" EXACT [] synonym: "cranial nerve ganglion" EXACT [] synonym: "cranial neural ganglion" EXACT [] synonym: "cranial neural tree organ ganglion" EXACT [OBOL:automatic] synonym: "ganglion of cranial neural tree organ" EXACT [OBOL:automatic] synonym: "cranial ganglia" RELATED [] synonym: "cranial ganglion" EXACT [] synonym: "head ganglion" RELATED [] synonym: "presumptive cranial ganglia" RELATED [ZFA:0000013] synonym: "ganglion of cranial nerve" EXACT [FMA:54502] xref: FMA:54502 ! ganglion of cranial nerve xref: MA:0000213 ! cranial ganglion/nerve xref: BTO:0000106 xref: EFO:0000902 ! cranial ganglion xref: VHOG:0000076 ! cranial ganglion xref: MA:0000214 ! cranial ganglion xref: MAT:0000200 ! cranial ganglion xref: MIAA:0000200 ! cranial ganglion xref: TAO:0000013 ! cranial ganglia xref: XAO:0000027 ! cranial ganglion xref: ZFA:0000013 ! cranial ganglion xref: EMAPA:16659 ! cranial of ganglion of central nervous system of nervous system of organ system is_a: UBERON:0000045 ! ganglion relationship: part_of UBERON:0000033 ! head intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0001785 ! cranial nerve xref: SCTID:244448001 ! Entire cranial nerve ganglion property_value: external_definition "Ganglion which is located in the head.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000013", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0009992 name: cranial sensory ganglion def: "the ganglion found on the root of each cranial nerve, containing the cell bodies of afferent (sensory) neurons. " [http://medical-dictionary.thefreedictionary.com/cranial+sensory+ganglion] comment: Editor note: check this - merge into cranial ganglion? WP: the geniculate, petrosal and nodose ganglia, appended respectively to cranial nerves VII, IX and X. Other ontology notes: has no subtypes in FMA synonym: "cranial nerve sensory ganglion" EXACT [FMA:5887] synonym: "ganglion sensorium cranialium" EXACT [FMA:5887] synonym: "sensory ganglion of cranial nerve" EXACT [FMA:5887] is_a: UBERON:0001800 {source="FMA"} ! sensory ganglion is_a: UBERON:0001714 {source="cjm"} ! cranial ganglion xref: FMA:5887 ! cranial sensory ganglion [Term] id: UBERON:0001715 name: oculomotor nuclear complex def: "The fibers of the oculomotor nerve arise from a nucleus in the midbrain, which lies in the gray substance of the floor of the cerebral aqueduct and extends in front of the aqueduct for a short distance into the floor of the third ventricle. From this nucleus the fibers pass forward through the tegmentum, the red nucleus, and the medial part of the substantia nigra, forming a series of curves with a lateral convexity, and emerge from the oculomotor sulcus on the medial side of the cerebral peduncle. The nucleus of the oculomotor nerve does not consist of a continuous column of cells, but is broken up into a number of smaller nuclei, which are arranged in two groups, anterior and posterior. Those of the posterior group are six in number, five of which are symmetrical on the two sides of the middle line, while the sixth is centrally placed and is common to the nerves of both sides. The anterior group consists of two nuclei, an antero-medial and an antero-lateral . The nucleus of the oculomotor nerve, considered from a physiological standpoint, can be subdivided into several smaller groups of cells, each group controlling a particular muscle. A nearby nucleus, the Edinger-Westphal nucleus, is responsible for the autonomic functions of the oculomotor nerve, including pupillary constriction and lens accommodation. [WP,unvetted]." [Wikipedia:Nucleus_of_oculomotor_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "motor nucleus III" RELATED [] synonym: "nIII" RELATED [] synonym: "nucleus of oculomotor nerve" EXACT [] synonym: "nucleus of third cranial nerve" EXACT [] synonym: "oculomotor nucleus" EXACT [] synonym: "third cranial nerve nucleus" EXACT [] synonym: "oculomotor III nucleus" EXACT [MA:0001073] xref: FMA:54510 ! Oculomotor nuclear complex xref: NIF_GrossAnatomy:birnlex_1240 ! Oculomotor nuclear complex xref: TAO:0000553 ! oculomotor nucleus xref: ZFA:0000553 ! oculomotor nucleus xref: ncithesaurus:Oculomotor_Nucleus ! Oculomotor Nucleus xref: EFO:0002468 ! oculomotor nucleus xref: VHOG:0001389 ! oculomotor nucleus xref: MA:0001073 ! oculomotor III nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Cn3nucleus.png/200px-Cn3nucleus.png xref: EV:0100250 ! oculomotor nucleus xref: ABA:III ! Oculomotor nucleus xref: BM:MB-III ! oculomotor nucleus is_a: UBERON:0000126 ! cranial nerve nucleus relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus synonym: "nucleus nervi oculomotorii" EXACT LATIN [FMA:TA, FMA:54510] xref: SCTID:362457000 ! Entire oculomotor nucleus xref: EHDAA2:0004211 ! midbrain oculomotor nucleus xref: UMLS:C0228686 [Term] id: UBERON:0012315 name: incisive foramen def: "the point where the primary palate and both palatine shelves fuse." [Wikipedia:Incisive_foramen, https://missinglink.ucsf.edu/restricted/lm/CongenitalAnomalies/CleftLipPalate.html] synonym: "foramina incisiva" RELATED [Wikipedia:Incisive_foramen] synonym: "incisive foramina" RELATED [Wikipedia:Incisive_foramen] synonym: "incisive fossa" RELATED [Wikipedia:Incisive_foramen] synonym: "Stenson's foramen" EXACT [FMA:75305] is_a: UBERON:0000464 ! anatomical space relationship: adjacent_to UBERON:0005619 ! secondary palatal shelf relationship: adjacent_to UBERON:0005620 ! primary palate xref: FMA:75305 ! incisive foramen [Term] id: UBERON:0007375 name: roof of mouth def: "A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity. In mammals this is the combination of the primary palate (premaxilla) and the secondary palate. In early tetrapods it consists of the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones." [UBERON:cjm] comment: Editor notes: check subclasses to verify if they refer to a multi-tissue structure or a subdivision of the skeleton synonym: "roof of oral cavity" EXACT [] synonym: "roof of buccal cavity" EXACT [] synonym: "palate" RELATED [] synonym: "palatum" RELATED INCONSISTENT [] synonym: "primary or secondary palate" RELATED [] subset: grouping_class is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0001716 name: secondary palate def: "The part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences." [Wikipedia:Secondary_palate, http://www.indiana.edu/~anat550/hnanim/face/face.html] comment: Function notes: separates respiratory and oral passages. Taxon notes: present in mammals and some reptiles. A similar structure is found in crocodilians, but, in most other tetrapods, the oral and nasal cavities are not truly separate. The secondary palate is formed by bilateral medial extensions of maxillary processes. The extensions (palatine processes) meet at the midline, merging dorsally with nasal septum and rostrally with primary palate. The secondary palate (hard palate) separates nasal and oral cavities. Caudal extension of the secondary palate into the pharynx, forms a soft palate which divides the rostral pharynx into dorsal (nasopharynx) and ventral (oropharynx) chamber. subset: uberon_slim synonym: "palate" BROAD SENSU [MA:0002476, EMAPA:18948, GO:0060021] synonym: "palatum" BROAD [] synonym: "oral roof" EXACT [] synonym: "roof of mouth" RELATED [] synonym: "definitive palate" EXACT [EMAPA:18948] xref: FMA:54549 ! Palate xref: GAID:152 ! palate xref: MA:0002476 ! palate xref: EMAPA:18948 ! palate xref: ncithesaurus:Palate xref: BTO:0001779 ! palate xref: galen:Palate ! palate xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d4/Illu01_head_neck.jpg/200px-Illu01_head_neck.jpg xref: MESH:A14.521.658 ! palate xref: SCTID:181227004 ! Entire palate xref: ncithesaurus:Secondary_Palate ! secondary palate is_a: UBERON:0007375 ! roof of mouth relationship: adjacent_to UBERON:0000167 ! oral cavity relationship: adjacent_to UBERON:0001707 ! nasal cavity relationship: part_of UBERON:0000165 {source="FMA"} ! mouth relationship: part_of UBERON:0001709 {source="EMAPA"} ! upper jaw region relationship: develops_from UBERON:0005619 {notes="fusion", source="http://www.indiana.edu/~anat550/hnanim/face/face.html"} ! secondary palatal shelf relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda synonym: "palatum" RELATED LATIN [Wikipedia:Palate] synonym: "palatum secundarium; palatum definitivum" RELATED LATIN [Wikipedia:Secondary_palate] xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Pig_snout_sagittal_cut.jpg xref: UMLS:C0700374 xref: UMLS:C1519217 [Term] id: UBERON:0012316 name: primitive palate def: "Roof of the buccal cavity, formed from the fusion of vomer, pterygoid, parasphenoid, palatine, ectopterygoid." [ISBN10:0073040584 "Vertebrates\, Kardong"] synonym: "palate" RELATED [ZFA:0005509] is_a: UBERON:0007375 ! roof of mouth relationship: part_of UBERON:0012072 {source="Kardong", notes="palatal series"} ! palatal part of dermatocranium xref: ZFA:0005509 ! palate xref: TAO:0002093 ! palate xref: AAO:0010535 ! palate property_value: external_definition "Roof of the mouth lined with ciliated epithelium.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010535", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Anatomical cluster that is the upper roof of the mouth that is underlain by bones such as the parasphenoid, vomer, metapterygoid, orbitosphenoid.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002093", date_retrieved="2012-08-14", source="TAO:wd"} property_value: homology_notes "Early tetrapod possessed a primary palate that included the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones. Therapsid evolved a partial secondary palate formed by the medial extension of the premaxilla and maxilla. Mammals have a secondary palate that, in addition to extensions of the premaxilla and maxilla, includes part of the palatine bone[VHOG]" xsd:string {external_class="VHOG:0000362", ontology="VHOG", source="ISBN:978-0072528305 Kardong", source="http://bgee.unil.ch/", date_retrieved="2012-11-28"} [Term] id: UBERON:0005620 name: primary palate def: "The part of the palate formed from the intermaxillary segment." [Wikipedia:Primary_palate, http://www.indiana.edu/~anat550/hnanim/face/face.html] subset: vertebrate_core synonym: "palatum primarium" RELATED LATIN [Wikipedia:Primitive_palate] synonym: "processus palatinus medianus" RELATED LATIN [Wikipedia:Primitive_palate] synonym: "primary palate" RELATED [Wikipedia:Primitive_palate] synonym: "primary palate process" EXACT [EHDAA2:0001499] synonym: "primitive palate" RELATED [VHOG:0000362] xref: VHOG:0000362 ! primary palate xref: MA:0001583 ! primary palate xref: EHDAA2:0001499 ! primary palate process xref: EHDAA2:0001496 ! primary palate xref: EMAPA:17642 ! primary palate of premaxilla of maxillary process xref: EMAPA:17934 ! primary palate of premaxilla of upper jaw is_a: UBERON:0007375 ! roof of mouth relationship: part_of UBERON:0002244 {source="VHOG", notes="consider reversing"} ! premaxilla relationship: develops_from UBERON:0007238 {source="EHDAA2-abduced"} ! 1st arch maxillary component relationship: develops_from UBERON:0009714 {source="Wikipedia", source="http://www.indiana.edu/~anat550/hnanim/face/face.html"} ! intermaxillary process xref: ncithesaurus:Primary_Palate ! Primary Palate xref: SCTID:359541001 ! Primary palate property_value: external_definition "The shelf separating the oral and nasal cavities that is formed during early embryonic development from protrusions of tissue between the olfactory pits. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000362", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/primary+palate", source="http://bgee.unil.ch/"} property_value: homology_notes "Early tetrapod possessed a primary palate that included the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones. Therapsid evolved a partial secondary palate formed by the medial extension of the premaxilla and maxilla. Mammals have a secondary palate that, in addition to extensions of the premaxilla and maxilla, includes part of the palatine bone[VHOG]" xsd:string {external_class="VHOG:0000362", ontology="VHOG", source="ISBN:978-0072528305 Kardong", source="http://bgee.unil.ch/", date_retrieved="2012-11-28"} xref: UMLS:C1268540 [Term] id: UBERON:0005619 name: secondary palatal shelf def: "the outgrowths of the embryonic maxillary prominences that come together during prenatal development to form the secondary palate" [http://medical-dictionary.thefreedictionary.com/palatal+shelves, http://www.indiana.edu/~anat550/hnanim/face/face.html] comment: Consider splitting into embryonic/fully formed synonym: "lateral palatine process" EXACT [http://medical-dictionary.thefreedictionary.com/palatal+shelf] synonym: "secondary palatal shelf" EXACT [] synonym: "palatal shelves" RELATED PLURAL [] synonym: "palatal shelf" EXACT [MA:0001581] xref: MA:0001581 ! palatal shelf xref: EHDAA2:0001364 ! palatal shelf xref: EMAPA:17362 ! palatal shelf of maxillary process xref: EMAPA:17930 ! palatal shelf of upper jaw xref: VHOG:0000378 ! palatal shelf xref: EHDAA:9283 ! secondary palatal shelf is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0003277 {source="EHDAA2"} ! skeleton of upper jaw relationship: develops_from UBERON:0005868 {source="cjm"} ! maxillary prominence synonym: "palatine shelf" RELATED [VHOG:0000378] property_value: external_definition "The outgrowths of the embryonic maxillae that come together during prenatal development to form the secondary palate. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000378", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/palatal", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003216 name: hard palate def: "anterior portion of the palate consisting of bone and mucous membranes[GO]. The hard palate is formed from bony processes of the maxilla, premaxilla and palatine[Kardong]." [GO:0060022, Wikipedia:Hard_palate] comment: In FMA this is divided into bony parts and submucosa subset: uberon_slim synonym: "hard palate" EXACT [] xref: FMA:55023 ! Hard palate xref: GAID:221 ! hard palate xref: MA:0002477 ! hard palate xref: MAT:0000161 ! hard palate xref: MIAA:0000161 ! hard palate xref: EMAPA:18952 ! hard palate xref: ncithesaurus:Hard_Palate ! Hard Palate xref: MESH:A02.835.232.781.324.502.660 ! hard palate is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: part_of UBERON:0001716 {source="EMAPA", notes="check this"} ! secondary palate xref: SCTID:245778002 ! Entire hard palate synonym: "palatum durum" EXACT LATIN [Wikipedia:Hard_palate] xref: http://upload.wikimedia.org/wikipedia/commons/f/f6/Illu_mouth.jpg xref: UMLS:C0226901 [Term] id: UBERON:0001733 name: soft palate def: "soft tissue constituting the back of the roof of the mouth. The soft palate is distinguished from the hard palate at the front of the mouth in that it does not contain bone[WP]. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate[GO]." [GO:0060023, Wikipedia:Soft_palate] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "muscular palate" RELATED [Wikipedia:Soft_palate] synonym: "velum" RELATED [Wikipedia:Soft_palate] xref: FMA:55021 ! Soft palate xref: GAID:1284 ! soft palate xref: MA:0002412 ! soft palate xref: MAT:0000039 ! soft palate xref: MIAA:0000039 ! soft palate xref: EMAPA:18949 ! soft palate xref: ncithesaurus:Soft_Palate xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/81/Tonsils_diagram.jpg/200px-Tonsils_diagram.jpg xref: MESH:A14.549.617.780 ! soft palate is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: part_of UBERON:0001716 {source="MA"} ! secondary palate relationship: part_of UBERON:0000165 {source="FMA"} ! mouth xref: SCTID:245784004 ! Entire soft palate synonym: "palatum molle, velum palatinum" RELATED LATIN [Wikipedia:Soft_palate] xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Tonsils_diagram.jpg property_value: external_definition "A muscular arch-shaped structure [is this an 'anatomical cluster�?] that is composed of the musculus uvuli and parts of tensor veli palatini, levator veli palatini, palatoglossus and palatopharyngeus and attaches to the hard palate and modulates the connections between the oral cavity and pharynx soft tissue arch .[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C0030219 [Term] id: UBERON:0010126 name: future nucleus ambiguus is_a: UBERON:0002020 ! gray matter of neuraxis intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: develops_into UBERON:0001719 ! nucleus ambiguus xref: EHDAA2:0004647 ! future nucleus ambiguus def: "A gray matter of neuraxis that develops_into a nucleus ambiguus." [OBOL:automatic] [Term] id: UBERON:0001719 name: nucleus ambiguus def: "The nucleus ambiguus (literally 'ambiguous nucleus') is a region of histologically disparate cells located just dorsal to the inferior olivary nucleus in the lateral portion of the upper medulla. It receives upper motor neuron innervation directly via the corticobulbar tract This nucleus gives rise to the efferent motor fibers of the vagus nerve terminating in the laryngeal and pharyngeal muscles, as well as to the efferent motor fibers of the glossopharyngeal nerve (CN IX) terminating in the stylopharyngeus. [WP,unvetted]." [Wikipedia:Nucleus_ambiguus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "ambiguus nucleus" EXACT [] xref: FMA:54588 ! Nucleus ambiguus xref: MA:0001050 ! nucleus ambiguus xref: NIF_GrossAnatomy:birnlex_2650 ! Nucleus ambiguus xref: ncithesaurus:Nucleus_Ambiguus ! Nucleus Ambiguus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/93/Gray695.png/200px-Gray695.png xref: EV:0100292 ! nucleus ambiguus xref: ABA:AMB ! Nucleus ambiguus xref: BM:Me-AMB ! nucleus ambiguus is_a: UBERON:0011775 {source="Wikipedia"} ! vagus nerve nucleus relationship: part_of UBERON:0001896 {source="MA"} ! medulla oblongata relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus xref: SCTID:280184006 ! Entire nucleus ambiguus xref: EHDAA2:0004305 ! nucleus ambiguus relationship: immediate_transformation_of UBERON:0010126 {evidence="definitional"} ! future nucleus ambiguus xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Gray695.png xref: UMLS:C0152400 [Term] id: UBERON:0001720 name: cochlear nucleus def: "The cochlear nuclei consist of: (a) the dorsal cochlear nucleus, corresponding to the tuberculum acusticum on the dorso-lateral surface of the inferior peduncle; and (b) the ventral or accessory cochlear nucleus, placed between the two divisions of the nerve, on the ventral aspect of the inferior peduncle. [WP,unvetted]." [Wikipedia:Cochlear_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "cochlear nucleus of acoustic nerve" EXACT [] synonym: "cochlear nucleus of eighth cranial nerve" EXACT [] synonym: "nucleus of cochlear nerve" EXACT [] synonym: "statoacoustic (VIII) nucleus" EXACT [] synonym: "vestibulocochlear nucleus" RELATED [] synonym: "cochlear VIII nucleus" EXACT [MA:0001012] xref: FMA:54603 ! Cochlear nucleus xref: GAID:601 ! cochlear nucleu xref: ZFA:0001638 ! statoacoustic (VIII) nucleus xref: MA:0001012 ! cochlear VIII nucleus xref: ncithesaurus:Cochlear_Nucleus ! Cochlear Nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/52/Gray691.png/200px-Gray691.png xref: MESH:A08.186.211.132.810.428.600.135 ! cochlear nucleu is_a: UBERON:0000126 ! cranial nerve nucleus relationship: part_of UBERON:0000988 ! pons xref: SCTID:362463009 ! Entire cochlear nucleus xref: TAO:0002243 ! statoacoustic (VIII) nucleus [Term] id: UBERON:0007228 name: vestibular nucleus def: "The vestibular nuclei are the cranial nuclei for the vestibular nerve. [WP,unvetted]." [Wikipedia:Vestibular_nuclei] comment: See comments for 'vestibular nuclear complex synonym: "vestibular nucleus of acoustic nerve" EXACT [FMA:54602] synonym: "vestibular nucleus of eighth cranial nerve" EXACT [FMA:54602] synonym: "vestibular VIII nucleus" EXACT [MA:0001032] xref: FMA:54602 ! vestibular nucleus xref: ncithesaurus:Vestibular_Nucleus ! Vestibular Nucleus xref: EV:0100254 ! vestibular nuclei (also: UBERON:0002673 'vestibular nuclear complex') xref: MA:0001032 ! vestibular VIII nucleus is_a: UBERON:0000126 ! cranial nerve nucleus relationship: part_of UBERON:0002673 ! vestibular nuclear complex xref: SCTID:362462004 ! Entire vestibular nucleus xref: http://upload.wikimedia.org/wikipedia/commons/5/52/Gray691.png xref: UMLS:C0042600 [Term] id: UBERON:0002673 name: vestibular nuclear complex def: "The vestibular nuclei are the cranial nuclei for the vestibular nerve. [WP,unvetted]." [Wikipedia:Vestibular_nuclei, http://www.sciencedirect.com/science/article/pii/S0079612305510069, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3413105&group_id=36855] comment: Editor notes: In TA they are grouped in both the pons and medulla; WP+MA says the SVN is in the pons, and GO includes VNC development under pons development, but this is not supported by ABA. Todo - check with NIF subset: uberon_slim synonym: "vestibular nuclei" EXACT [FMA:72239] synonym: "vestibular nucleus" RELATED [GO:0021750] synonym: "vestibular nuclei in medulla oblongata" EXACT [FMA:72239] xref: FMA:72239 ! Vestibular nuclear complex xref: NIF_GrossAnatomy:birnlex_1337 ! Vestibular nuclear complex xref: GAID:602 ! vestibular nuclei xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/52/Gray691.png/200px-Gray691.png xref: BTO:0004368 ! vestibular nucleus xref: MESH:A08.186.211.132.810.428.600.800 ! vestibular nuclei xref: EV:0100254 ! vestibular nuclei (also: UBERON:0007228 'vestibular nucleus') xref: ABA:VNC ! Vestibular nuclei xref: BM:Me-VS ! vestibular nuclei is_a: UBERON:0000125 ! neural nucleus relationship: part_of UBERON:0001896 {source="ABA", source="FMA", source="NIF"} ! medulla oblongata relationship: part_of UBERON:0004681 {source="Wikipedia:Vestibular_nuclei"} ! vestibular system relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus synonym: "nuclei vestibulares in medulla oblongata" EXACT LATIN [FMA:TA, FMA:72239] synonym: "nuclei vestibulares" RELATED LATIN [Wikipedia:Vestibular_nuclei] [Term] id: UBERON:0001721 name: inferior vestibular nucleus def: "The inferior vestibular nucleus is the vestibular nucleus which lies near the fourth ventricle. [WP,unvetted]." [Wikipedia:Inferior_vestibular_nucleus] subset: uberon_slim synonym: "descending vestibular nucleus" EXACT [FMA:54608] synonym: "spinal vestibular nucleus" EXACT [FMA:54608] xref: FMA:54608 ! Inferior vestibular nucleus xref: MA:0001054 ! spinal vestibular nucleus xref: ncithesaurus:Spinal_Vestibular_Nucleus ! Spinal Vestibular Nucleus xref: EV:0100258 ! inferior vestibular nuclei xref: BTO:0004369 ! inferior vestibular nucleus xref: ABA:SPIV ! Spinal vestibular nucleus xref: BM:Me-VS-VSI ! inferior vestibular nucleus is_a: UBERON:0007228 ! vestibular nucleus relationship: spatially_disjoint_from UBERON:0007230 {source="ABA"} ! lateral vestibular nucleus relationship: spatially_disjoint_from UBERON:0001722 {source="ABA"} ! medial vestibular nucleus relationship: spatially_disjoint_from UBERON:0007227 {source="ABA"} ! superior vestibular nucleus xref: SCTID:280175006 ! Inferior vestibular nucleus synonym: "nucleus vestibularis inferior" RELATED LATIN [Wikipedia:Inferior_vestibular_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Gray700.png xref: UMLS:C0175498 [Term] id: UBERON:0001722 name: medial vestibular nucleus def: "The medial vestibular nucleus is one of the vestibular nuclei. It is located in the medulla oblongata. Lateral vestibulo-spinal tract (lateral vestibular nucleus “Deiters”)- via ventrolateral medulla and spinal cord to ventral funiculus (lumbo-sacral segments). Ipsilaterally for posture Medial vestibulo-spinal tract (medial, lateral, inferior, vestibular nuclei), bilateral projection via descending medial longitudinal fasciculus to cervical segments. DESCENDING MLF. Bilaterally for head/neck/eye movements [WP,unvetted]." [Wikipedia:Medial_vestibular_nucleus] subset: uberon_slim synonym: "medial nucleus" RELATED [Wikipedia:Medial_vestibular_nucleus] synonym: "chief vestibular nucleus" EXACT [FMA:54611] synonym: "dorsal vestibular nucleus" EXACT [FMA:54611] synonym: "nucleus of schwalbe" EXACT [FMA:54611] synonym: "principal vestibular nucleus" EXACT [FMA:54611] synonym: "schwalbe's nucleus" EXACT [FMA:54611] synonym: "triangular nucleus" EXACT [FMA:54611] xref: FMA:54611 ! Medial vestibular nucleus xref: MA:0001048 ! medial vestibular nucleus xref: ncithesaurus:Medial_Vestibular_Nucleus ! Medial Vestibular Nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Gray700.png/200px-Gray700.png xref: BTO:0004371 ! medial vestibular nucleus xref: ABA:MV ! Medial vestibular nucleus xref: BM:Me-VS-VSM ! medial vestibular nucleus is_a: UBERON:0007228 ! vestibular nucleus relationship: spatially_disjoint_from UBERON:0007230 {source="ABA"} ! lateral vestibular nucleus relationship: spatially_disjoint_from UBERON:0001721 {source="ABA"} ! inferior vestibular nucleus relationship: spatially_disjoint_from UBERON:0007227 {source="ABA"} ! superior vestibular nucleus synonym: "nucleus triangularis" EXACT LATIN [FMA:TA, FMA:54611] xref: SCTID:280174005 ! Entire medial vestibular nucleus synonym: "nucleus vestibularis medialis" RELATED LATIN [Wikipedia:Medial_vestibular_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Lower_pons_horizontal_KB.svg xref: UMLS:C0036385 [Term] id: UBERON:0007227 name: superior vestibular nucleus def: "The superior vestibular nucleus is the dorso-lateral part of the vestibular nucleus and receives collaterals and terminals from the ascending branches of the vestibular nerve. Its axons terminate in much the same manner as do those from the lateral nucleus." [Wikipedia:Superior_vestibular_nucleus] synonym: "Bechterew's nucleus" RELATED [Wikipedia:Superior_vestibular_nucleus] synonym: "nucleus of Bechterew" EXACT [FMA:54617] xref: FMA:54617 ! superior vestibular nucleus xref: BTO:0004372 ! superior vestibular nucleus xref: EV:0100257 ! superior vestibular nuclei xref: ABA:SUV ! Superior vestibular nucleus xref: BM:Me-VS-VSS ! superior vestibular nucleus is_a: UBERON:0007228 ! vestibular nucleus relationship: spatially_disjoint_from UBERON:0007230 {source="ABA"} ! lateral vestibular nucleus relationship: spatially_disjoint_from UBERON:0001722 {source="ABA"} ! medial vestibular nucleus relationship: spatially_disjoint_from UBERON:0001721 {source="ABA"} ! inferior vestibular nucleus xref: ncithesaurus:Superior_Vestibular_Nucleus ! Superior Vestibular Nucleus synonym: "nucleus vestibularis superior" RELATED LATIN [Wikipedia:Superior_vestibular_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray761.png xref: UMLS:C0228757 [Term] id: UBERON:0007230 name: lateral vestibular nucleus def: "The lateral vestibular nucleus (Deitersbs nucleus) is the continuation upward and lateralward of the principal nucleus, and in it terminate many of the ascending branches of the vestibular nerve." [Wikipedia:Lateral_vestibular_nucleus] synonym: "Deiter's nucleus" EXACT [FMA:54614] synonym: "Deiters' nucleus" EXACT [FMA:54614] synonym: "lateral nucleus of Deiters" EXACT [FMA:54614] synonym: "nucleus of Deiters" EXACT [FMA:54614] xref: FMA:54614 ! lateral vestibular nucleus xref: BTO:0004370 ! lateral vestibular nucleus xref: GAID:603 ! lateral vestibular nucleu xref: MESH:A08.186.211.132.810.428.600.800.800 ! lateral vestibular nucleu xref: ABA:LAV ! Lateral vestibular nucleus xref: BM:Me-VS-VSL ! lateral vestibular nucleus is_a: UBERON:0007228 ! vestibular nucleus relationship: spatially_disjoint_from UBERON:0001722 {source="ABA"} ! medial vestibular nucleus relationship: spatially_disjoint_from UBERON:0001721 {source="ABA"} ! inferior vestibular nucleus relationship: spatially_disjoint_from UBERON:0007227 {source="ABA"} ! superior vestibular nucleus xref: ncithesaurus:Lateral_Vestibular_Nucleus ! Lateral Vestibular Nucleus xref: SCTID:280176007 ! Entire lateral vestibular nucleus synonym: "nucleus vestibularis lateralis" RELATED LATIN [Wikipedia:Lateral_vestibular_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray761.png xref: UMLS:C0011193 [Term] id: UBERON:0011268 name: sublingua def: "a secondary tongue located below the primary tongue in prosimian primates and some primitive mammals. This structure does not have taste buds or salivary glands" [Wikipedia:Sublingua] synonym: "under-tongue" RELATED [Wikipedia:Sublingua] synonym: "second tongue" RELATED [Wikipedia:Sublingua] is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0000165 ! mouth relationship: never_in_taxon NCBITaxon:9606 {source="Wikipedia"} ! Homo sapiens relationship: only_in_taxon NCBITaxon:9347 {source="Wikipedia"} ! Eutheria disjoint_from: UBERON:0006689 ! frenulum of tongue [Term] id: UBERON:0000378 ! tongue muscle name: tongue muscle def: "the muscular portion of the tongue." [MP:0004136, Wikipedia:Muscles_of_tongue] synonym: "muscle of tongue" EXACT [FMA:46689] xref: BTO:0001386 ! tongue muscle xref: FMA:46689 ! Muscle of tongue xref: ncithesaurus:Tongue_Muscle ! Tongue Muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001723 ! tongue relationship: has_developmental_contribution_from UBERON:0005594 {source="ISBN10:1607950324"} ! head somite xref: SCTID:244781004 ! Muscle of tongue synonym: "musculi linguae" RELATED LATIN [Wikipedia:Muscles_of_tongue] xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Gray1019.png xref: UMLS:C0448325 [Term] id: UBERON:0001723 name: tongue def: "The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech[GO]." [GO:0043586, Wikipedia:Tongue] comment: editor notes - in MA the tongue is part of the oral region, which in uberon is treated as the oral opening. consider revising oral opening - oral region equivalence. Taxon notes: Many species of fish have small folds at the base of their mouths that might informally be called tongues, but they lack a muscular structure like the true tongues found in most tetrapods. Development notes: The tongue has contributions from all pharyngeal arches which changes with time. The tongue initially begins as swelling rostral to foramen cecum, the median tongue bud.. tongue muscles derive from the somites - http://php.med.unsw.edu.au/embryology/index.php?title=Tongue_Development#Pharyngeal_Arch_Contributions subset: uberon_slim subset: vertebrate_core xref: BTO:0001385 xref: EFO:0000833 ! tongue xref: EHDAA:9144 ! tongue xref: FMA:54640 ! Tongue xref: GAID:816 ! tongue xref: VHOG:0000419 ! tongue xref: MA:0000347 ! tongue xref: MAT:0000040 ! tongue xref: MIAA:0000040 ! tongue xref: OpenCyc:Mx4rvVjmJ5wpEbGdrcN5Y29ycA_53KXLq9EdqAAAACs6hnmQ xref: XAO:0000446 ! tongue xref: ZFA:0005333 ! tongue xref: ncithesaurus:Tongue ! Tongue xref: EHDAA2:0002062 ! tongue xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a6/Tongue.agr.jpg/200px-Tongue.agr.jpg xref: EMAPA:17185 ! tongue of pharynx of foregut xref: EMAPA:18870 ! tongue of pharynx of gut xref: MESH:A14.549.885 ! tongue xref: EV:0100058 ! tongue is_a: UBERON:0000020 {source="GO"} ! sense organ relationship: part_of UBERON:0001033 ! gustatory system relationship: part_of UBERON:0000165 {source="BTO", source="FMA"} ! mouth relationship: part_of UBERON:0001033 {source="MA"} ! gustatory system relationship: adjacent_to UBERON:0000166 ! oral opening relationship: has_developmental_contribution_from UBERON:0006260 {notes="anterior 2/3"} ! lingual swellings relationship: has_developmental_contribution_from UBERON:0006757 {source="Wikipedia"} ! lateral lingual swelling relationship: has_developmental_contribution_from UBERON:0006756 {source="Wikipedia"} ! tuberculum impar relationship: develops_from UBERON:0008814 ! pharyngeal system xref: AAO:0010360 ! tongue xref: SCTID:181226008 ! Entire tongue subset: organ_slim relationship: immediate_transformation_of UBERON:0010056 {evidence="definitional"} ! future tongue xref: TAO:0005333 ! tongue synonym: "glossus" RELATED [Wikipedia:Tongue] xref: http://upload.wikimedia.org/wikipedia/commons/a/a6/Tongue.agr.jpg property_value: external_definition "Muscular organ in the floor of the mouth.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} property_value: external_definition "A mobile mass of muscular tissue that is covered with mucous membrane, occupies much of the cavity of the mouth, forms part of its floor, bears the organ of taste, and assists in chewing and swallowing. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000419", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/tongue", source="http://bgee.unil.ch/"} property_value: homology_notes "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {external_class="VHOG:0000419", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x Iwasaki S\, Evolution of the structure and function of the vertebrate tongue. J Anat (2002)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "lingual" xsd:string property_value: has_relational_adjective "glossal" xsd:string xref: UMLS:C0040408 [Term] id: UBERON:0011876 name: body of tongue def: "the oral part of the tongue anterior to the terminal sulcus." [http://www.drugs.com/dict/body-of-tongue.html] synonym: "corpus linguae" EXACT LATIN [http://www.drugs.com/dict/body-of-tongue.html] synonym: "tongue body" EXACT [FMA:54641] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001723 {source="FMA"} ! tongue xref: FMA:54641 ! body of tongue xref: SCTID:362090005 ! Entire body of tongue [Term] id: UBERON:0011877 name: margin of tongue def: "the lateral border that separates the dorsum from the inferior surface of the tongue on each side, the two borders meeting anteriorly at the apex.." [http://www.drugs.com/dict/margin-of-tongue.html] synonym: "margo linguae" EXACT LATIN [http://www.drugs.com/dict/margin-of-tongue.html] synonym: "tongue margin" EXACT [FMA:54650] is_a: UBERON:0006800 {source="FMA"} ! anatomical line relationship: part_of UBERON:0001723 ! tongue xref: FMA:54650 ! margin of tongue xref: SCTID:368572007 ! Entire right margin of tongue xref: SCTID:368594004 ! Entire left margin of tongue [Term] id: UBERON:0010032 name: anterior part of tongue def: "The portion of the tongue in front of the terminal sulcus. At the apex, thin and narrow, it is directed forward against the lingual surfaces of the lower incisor teeth. It is derived primarily from the first pharyngeal arch." [Wikipedia:Anterior_tongue] comment: AO notes: check NCIT. Development notes: The lateral lingual swellings grow and fuse with eachother, encompassing the tuberculum impar to provide the ectodermally derived mucosa of the anterior 2/3 of the tongue xref: FMA:229084 ! anterior part of tongue xref: ncithesaurus:Apex_of_the_Tongue ! Apex of the Tongue synonym: "anterior 2/3 of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "anterior 2/3 of tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "anterior two thirds of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "apex linguae" RELATED [Wikipedia:Anterior_tongue] synonym: "apex of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "buccal part of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "front of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "oral part of the tongue" RELATED [Wikipedia:Anterior_tongue] intersection_of: UBERON:0000064 ! organ part intersection_of: part_of UBERON:0001723 ! tongue intersection_of: develops_from UBERON:0006260 {source="ISBN10:1607950324"} ! lingual swellings synonym: "pars anterior dorsi linguae" RELATED LATIN [Wikipedia:Anterior_tongue] xref: http://upload.wikimedia.org/wikipedia/commons/4/4c/Illu04_tongue.jpg xref: UMLS:C0226946 [Term] id: UBERON:0010033 name: posterior part of tongue def: "The Posterior tongue, or pharyngeal part, is the part of the tongue behind the terminal sulcus. At its root, it is directed backward, and connected with the hyoid bone by the Hyoglossi and Genioglossi muscles and the hyoglossal membrane; with the epiglottis by three folds (glossoepiglottic) of mucous membrane; with the soft palate by the glossopalatine arches; and with the pharynx by the Constrictores pharyngis superiores and the mucous membrane. It is derived primarily from the third pharyngeal arch. (The second arch has a substantial contribution during fetal development, but this later atrophies. The fourth arch may also contribute, depending upon how the boundaries of the tongue are defined.)" [Wikipedia:Posterior_tongue] synonym: "base of tongue" EXACT [Wikipedia:Posterior_tongue] synonym: "base of the tongue" RELATED [Wikipedia:Posterior_tongue] synonym: "pharyngeal part of the tongue" RELATED [Wikipedia:Posterior_tongue] synonym: "posterior 1/3 of the tongue" RELATED [Wikipedia:Posterior_tongue] synonym: "posterior third of tongue" RELATED [Wikipedia:Posterior_tongue] synonym: "radix linguae" RELATED [Wikipedia:Posterior_tongue] synonym: "pars posterior (dorsum linguae)" EXACT [FMA:54645] synonym: "pars posterior linguae" EXACT LATIN [FMA:TA] synonym: "pars postsulcalis (dorsum linguae)" EXACT [FMA:54645] synonym: "pharyngeal part of tongue" EXACT [FMA:54645] synonym: "pharyngeal portion of dorsum of tongue" EXACT [FMA:54645] synonym: "posterior part of dorsum of tongue" EXACT [FMA:54645] synonym: "postsulcal part of dorsum of tongue" EXACT [FMA:54645] synonym: "pars posterior dorsi linguae" EXACT LATIN [Wikipedia:Posterior_tongue] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0009471 {source="FMA"} ! dorsum of tongue relationship: has_developmental_contribution_from UBERON:0003114 {source="Wikipedia"} ! pharyngeal arch 3 xref: FMA:54645 ! postsulcal part of dorsum of tongue xref: ncithesaurus:Base_of_the_Tongue ! Base of the Tongue xref: http://upload.wikimedia.org/wikipedia/commons/4/4c/Illu04_tongue.jpg xref: SCTID:362094001 ! Entire pharyngeal portion of dorsum of tongue xref: UMLS:C0226958 [Term] id: UBERON:0001724 name: sphenoidal sinus def: "One of the paired paranasal sinuses, located in the body of the sphenoid bone and communicating with the highest meatus of the nasal cavity on the same side[MESH]. The sphenoidal sinuses (or sphenoid) contained within the body of the sphenoid vary in size and shape; owing to the lateral displacement of the intervening septum they are rarely symmetrical. The following are their average measurements: vertical height, 2.2 cm. ; transverse breadth, 2 cm. ; antero-posterior depth, 2.2 cm. [WP,unvetted]." [Wikipedia:Sphenoidal_sinus, MESH:A04.531.621.827] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "sphenoid sinus" EXACT [] synonym: "sinus sphenoidalis" RELATED LATIN [Wikipedia:Sphenoidal_sinus] xref: FMA:54683 ! Sphenoidal sinus xref: GAID:359 ! sphenoid sinus xref: MA:0001795 ! sphenoid sinus xref: ncithesaurus:Sphenoid_Sinus xref: OpenCyc:Mx4rwEIoz5wpEbGdrcN5Y29ycA ! sphenoid sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Gray856.png/200px-Gray856.png xref: MESH:A04.531.621.827 ! sphenoid sinus is_a: UBERON:0001825 {source="MA"} ! paranasal sinus relationship: part_of UBERON:0009639 ! body of sphenoid relationship: in_lateral_side_of UBERON:0003129 ! skull xref: SCTID:181207000 ! Entire sphenoid sinus xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray856.png relationship: in_lateral_side_of UBERON:0009639 {source="FMA-abduced-lr"} ! body of sphenoid xref: UMLS:C0037885 [Term] id: UBERON:0001725 name: cranial synchondrosis def: "the cartilaginous joints of the skull; these include sphenoethmoidal synchondrosis, sphenooccipital synchondrosis, sphenopetrosal synchondrosis, petrooccipital synchondrosis, anterior intraoccipital synchondrosis and posterior intraoccipital synchondrosis." [http://www.medilexicon.com/medicaldictionary.php?t=87514] xref: FMA:54816 ! Cranial synchondrosis xref: MA:0001502 ! cranial synchondrosis is_a: UBERON:0002215 {source="FMA"} ! synchondrosis intersection_of: UBERON:0002215 ! synchondrosis intersection_of: part_of UBERON:0003129 ! skull xref: SCTID:314228003 ! Cranial synchondrosis [Term] id: UBERON:0001727 name: taste bud def: "Taste buds are small structures on the upper surface of the tongue, soft palate, upper esophagus and epiglottis that provide information about the taste of food being eaten. These structures are involved in detecting the five elements of taste perception: salty, sour, bitter, sweet, and umami (or savory). Via small openings in the tongue epithelium, called taste pores, parts of the food dissolved in saliva come into contact with the taste receptors. These are located on top of the taste receptor cells that constitute the taste buds. The taste receptor cells send information detected by clusters of various receptors and ion channels to the gustatory areas of the brain via the seventh, ninth and tenth cranial nerves. The human tongue has about 10,000 taste buds. [WP,unvetted]." [Wikipedia:Taste_bud] comment: Editor notes: todo - account for non-tongue taste buds. Development notes: arise by inductive interactions between epithelial cells and invading gustatory cells from chorda tympani (facial), glossophrayngeal and vagues nerves ISBN10:1607950324 (todo - request cell terms from CL) Taste buds form in greatest concentration on the dorsal surface of the tongue subset: uberon_slim subset: vertebrate_core synonym: "taste buds" RELATED PLURAL [Wikipedia:Taste_bud] synonym: "taste-bud" RELATED [Wikipedia:Taste_bud] synonym: "tastebud" EXACT [Wikipedia:Taste_bud] synonym: "tastebuds" RELATED PLURAL [Wikipedia:Taste_bud] synonym: "caliculus gustatorius" RELATED PLURAL [Wikipedia:Taste_bud] xref: BTO:0000989 xref: FMA:54825 ! Taste bud xref: GAID:815 ! taste bud xref: VHOG:0000130 ! taste bud xref: MA:0001591 ! taste bud xref: NIF_GrossAnatomy:birnlex_4101 ! Taste bud xref: OpenCyc:Mx4rvVjan5wpEbGdrcN5Y29ycA xref: TAO:0001074 ! taste bud xref: XAO:0000445 ! taste bud xref: ZFA:0001074 ! taste bud xref: OpenCyc:Mx4rvVjan5wpEbGdrcN5Y29ycA ! taste bud xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5a/Gray1018.png/200px-Gray1018.png xref: MESH:A08.800.550.700.120.800 ! taste bud is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: part_of UBERON:0001033 {source="ZFA"} ! gustatory system relationship: develops_from UBERON:0007690 {source="http://dev.biologists.org/content/128/22/4573.full"} ! early pharyngeal endoderm relationship: part_of UBERON:0001726 {source="Wikipedia"} ! papilla of tongue relationship: part_of UBERON:0002926 {source="NIF"} ! gustatory epithelium relationship: has_part GO:0008527 ! gustatory receptor relationship: has_part CL:0000209 {source="FMA"} ! taste receptor cell relationship: capable_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste xref: AAO:0010573 ! taste bud xref: SCTID:362099006 ! Entire taste bud xref: ncithesaurus:Taste_Bud ! taste bud synonym: "caliculus gustatorius" RELATED LATIN [Wikipedia:Taste_bud] xref: http://upload.wikimedia.org/wikipedia/commons/5/5a/Gray1018.png property_value: external_definition "A chemoreceptive organ.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010573", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "One of a number of receptor cell nests located in the epithelium of the papillae of the tongue and in the soft palate, epiglottis, and pharynx that mediate the sense of taste. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000130", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/taste+bud", source="http://bgee.unil.ch/"} property_value: homology_notes "Experients in amphibia have shown that an intrinsic feature of the pharyngeal endoderm is its ability to generate taste buds and this capacity must have been acquired by the endoderm at the origin of the vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000130", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0039337 [Term] id: UBERON:0001726 name: papilla of tongue synonym: "lingual papilla" EXACT [] synonym: "tongue papilla" EXACT [] xref: FMA:54819 ! Papilla of tongue xref: MA:0001593 ! tongue papilla xref: NIF_GrossAnatomy:birnlex_4102 ! Lingual papilla is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0009471 {source="FMA-modified"} ! dorsum of tongue xref: ncithesaurus:Papilla_of_the_Tongue ! Papilla of the Tongue xref: SCTID:368728006 ! Entire lingual papillae xref: UMLS:C0226964 [Term] id: UBERON:0000396 ! vallate papilla name: vallate papilla alt_id: UBERON:0002927 def: "Any one of the largest papilla of the tongue, 8 to 12 in number, arranged in the form of a V anterior to the sulcus terminalis of the tongue" [BTO:0001705, Wikipedia:Vallate_papilla] synonym: "vallate papilla of tongue" EXACT [] synonym: "circumvallate papilla of tongue" EXACT [FMA:54822] synonym: "papilla vallatae" EXACT PLURAL [FMA:TA, FMA:71449] synonym: "circumvallate papilla" EXACT [MA:0001594] synonym: "circumvallate papilla of tongue" EXACT [] xref: BTO:0001705 ! vallate papilla xref: FMA:54822 ! vallate papilla of tongue xref: EMAPA:18654 ! circumvallate papilla of epithelium of tongue of pharynx of foregut xref: EMAPA:18271 ! circumvallate papilla of tongue of pharynx of foregut xref: EMAPA:18871 ! circumvallate papilla of tongue of pharynx of gut xref: MA:0001594 ! circumvallate papilla xref: NIF_GrossAnatomy:birnlex_4106_2 ! Circumvallate papilla xref: ncithesaurus:Circumvallate_Papilla ! Circumvallate Papilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6c/Gray1015.png/200px-Gray1015.png xref: EMAPA:18654 ! circumvallate papilla of epithelium of tongue of pharynx of foregut xref: EMAPA:18271 ! circumvallate papilla of tongue of pharynx of foregut xref: EMAPA:18871 ! circumvallate papilla of tongue of pharynx of gut is_a: UBERON:0001726 ! papilla of tongue xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray1015.png xref: SCTID:69517000 ! Entire vallate papillae of tongue xref: UMLS:C1182961 [Term] id: UBERON:0013638 name: horny papilla of tongue comment: In carnivores, functions to hold on to meat as it is being cut by the teeth is_a: UBERON:0001726 ! papilla of tongue synonym: "horny papilla" EXACT [] synonym: "horny papillae" RELATED PLURAL [] [Term] id: UBERON:0013639 name: mechanical papilla of tongue is_a: UBERON:0001726 ! papilla of tongue synonym: "mechanical papilla" EXACT [] synonym: "mechanical papillae" RELATED PLURAL [] [Term] id: UBERON:0013476 name: dermal layer of tongue def: "." [PMID:23153189] synonym: "tongue (dermal layer)" EXACT [] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0002926 ! gustatory epithelium name: gustatory epithelium comment: editor note - see also epithelium of tongue and subclasses xref: FMA:62412 ! Gustatory epithelium xref: NIF_GrossAnatomy:birnlex_4099 ! Gustatory epithelium is_a: UBERON:0006934 {source="FMA"} ! sensory epithelium relationship: part_of UBERON:0001033 ! gustatory system relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0007691 name: gustatory pore def: "The minute opening of a taste bud on the surface of the oral mucosa through which the gustatory hairs of the specialised neuroepithelial gustatory cells project. " [http://www.mondofacto.com/facts/dictionary?gustatory+pore] synonym: "porus gustatorius" EXACT [http://www.mondofacto.com/facts/dictionary?gustatory+pore] synonym: "taste pore" EXACT [FMA:63589] xref: FMA:63589 ! gustatory pore xref: http://upload.wikimedia.org/wikipedia/commons/0/0e/Taste_bud.svg is_a: UBERON:0000161 {source="FMA"} ! orifice intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0001727 ! taste bud relationship: part_of UBERON:0001727 {source="FMA"} ! taste bud relationship: continuous_with UBERON:0000167 ! oral cavity xref: ncithesaurus:Taste_Pore ! Taste Pore xref: SCTID:368724008 ! Entire gustatory pore xref: UMLS:C0226971 [Term] id: UBERON:0001731 name: cavity of pharynx comment: Taxon notes: See notes for pharynx - as a grouping class this is probably too bad. We exclude WBbt:0005790 (pharyngeal lumen) because of the developmental relationship. Development notes: TOODO check synonym: "lumen of pharynx" EXACT [] synonym: "pharyngeal cavity" EXACT [] synonym: "cavitas pharyngealis" RELATED LATIN [] synonym: "cavitas pharyngis" RELATED [BTO:0002097] xref: FMA:54935 ! Cavity of pharynx xref: XAO:0000105 ! pharyngeal cavity xref: BTO:0002097 ! pharyngeal cavity xref: EMAPA:18381 ! lumen of pharynx of foregut xref: EMAPA:18869 ! lumen of pharynx of gut intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0006562 ! pharynx relationship: part_of UBERON:0006562 ! pharynx relationship: develops_from UBERON:0001041 {source="XAO"} ! foregut relationship: part_of UBERON:0001007 {source="XAO"} ! digestive system xref: AAO:0010435 ! pharyngeal cavity xref: SCTID:180543003 ! Entire pharyngeal cavity [Term] id: UBERON:0002372 name: tonsil def: "Portion of lymphoid tissue on either side of the throat." [Wikipedia:Tonsil] comment: Usage notes: the term 'tonsil' can be ambiguous, sometimes refering specifically to the palatine tonsil, sometimes generically to include the cecal tonsils of avians. This class represents lymphoid tissue that is part of the tonsillar ring, in the mouth/throat region subset: uberon_slim synonym: "Mandel" RELATED [BTO:0001387] xref: BTO:0001387 xref: FMA:9609 ! Tonsil xref: GAID:341 ! tonsil xref: VHOG:0001139 ! tonsil xref: MA:0000143 ! tonsil xref: OpenCyc:Mx4rvVivrZwpEbGdrcN5Y29ycA xref: ncithesaurus:Tonsil ! Tonsil xref: ncithesaurus:Tonsilar_Tissue ! tonsillar tissue xref: ncithesaurus:Tonsillar_Lymphoid_Tissue ! tonsillar lymphoid tissue xref: EFO:0001401 ! tonsil xref: OpenCyc:Mx4rvVivrZwpEbGdrcN5Y29ycA ! tonsil xref: MESH:A03.867.603.925 ! tonsil xref: EV:0100052 ! tonsil is_a: UBERON:0001961 {source="FMA"} ! mucosa-associated lymphoid tissue relationship: part_of UBERON:0001735 {source="cjm"} ! tonsillar ring relationship: located_in UBERON:0000167 ! oral cavity xref: UMLS:C0836921 xref: UMLS:C1519547 xref: UMLS:C1519548 [Term] id: UBERON:0002373 name: palatine tonsil def: "tonsils on the left and right sides at the back of the throat. one of the mucosa-associated lymphoid tissues (MALT), located at the entrance to the upper respiratory and gastrointestinal tracts to protect the body from the entry of exogenous material through mucosal sites[WP]." [Wikipedia:Palatine_tonsil] comment: Development notes: tonsillar fossa develops from dorsal portion of pouch 2. Note that pharyngeal and lingual tonsils do not develop from pharyngeal pouches[ISBN10:1607950324] subset: uberon_slim synonym: "faucial tonsil" EXACT [] synonym: "tonsil" BROAD [] xref: FMA:9610 ! Palatine tonsil xref: VHOG:0001140 ! palatine tonsil xref: MA:0000775 ! palatine tonsil xref: MAT:0000291 ! palatine tonsil xref: MIAA:0000291 ! palatine tonsil xref: ncithesaurus:Palatine_Tonsil ! Palatine Tonsil xref: EFO:0001977 ! palatine tonsil xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Illu_mouth.jpg/200px-Illu_mouth.jpg xref: BTO:0004714 ! palatine tonsil xref: EV:0100393 ! palatine tonsil is_a: UBERON:0002372 ! tonsil relationship: develops_from UBERON:0002539 {source="Wikipedia"} ! pharyngeal arch relationship: develops_from UBERON:0010023 {source="ISBN10:1607950324"} ! dorsal part of pharyngeal pouch 2 xref: SCTID:265787001 ! Entire palatine tonsil synonym: "tonsilla palatina" RELATED LATIN [Wikipedia:Palatine_tonsil] xref: http://upload.wikimedia.org/wikipedia/commons/f/f6/Illu_mouth.jpg xref: UMLS:C0040421 [Term] id: UBERON:0007250 name: lingual tonsil def: "The lingual tonsils are rounded masses of lymphatic tissue that cover the posterior region of the tongue. They are on the dorsal surface at the base of the tongue. Their lymphatic tissue are dense and nodular, their surface is covered with stratified squamous epithelium which invaginates as a single crypt into each lingual tonsil. They are partially surrounded by connective tissue placing them in the group of Partially-Encapsulated Lymphatic Organs, tonsils, the only one of its kind. They have associated mucous glands which are drained by ducts directly into the single tonsillar crypt." [Wikipedia:Lingual_tonsils] synonym: "lingual tonsillar tissue" EXACT [MA:0000773] xref: FMA:54836 ! lingual tonsil xref: MA:0000773 ! lingual tonsillar tissue is_a: UBERON:0002372 ! tonsil xref: ncithesaurus:Lingual_Tonsil ! Lingual Tonsil xref: SCTID:276957006 ! Entire lingual tonsil synonym: "tonsilla lingualis" RELATED LATIN [Wikipedia:Lingual_tonsils] xref: http://upload.wikimedia.org/wikipedia/commons/4/4c/Illu04_tongue.jpg relationship: in_lateral_side_of UBERON:0010033 {source="FMA-abduced-lr"} ! posterior part of tongue xref: UMLS:C0229871 [Term] id: UBERON:0001732 name: pharyngeal tonsil def: "Adenoids (or pharyngeal tonsils, or nasopharyngeal tonsils) are a mass of lymphoid tissue situated at the very back of the nose, in the roof of the nasopharynx, where the nose blends into the mouth. Normally, in children, they make a soft mound in the roof and posterior wall of the nasopharynx, just above and behind the uvula. [WP,unvetted]." [Wikipedia:Pharyngeal_tonsil] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "adenoid" EXACT [] synonym: "nasopharyngeal tonsil" EXACT [] synonym: "tonsil of luschka" EXACT [] synonym: "Rachenmandel" RELATED [BTO:0000777] xref: BTO:0000777 xref: FMA:54970 ! Pharyngeal tonsil xref: GAID:1288 ! adenoid xref: MA:0000774 ! nasopharyngeal tonsil xref: ncithesaurus:Pharyngeal_Tonsil ! Pharyngeal Tonsil xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/be/Gray994-adenoid.png/200px-Gray994-adenoid.png xref: MESH:A15.382.520.604.084 ! adenoid xref: EV:0100054 ! pharyngeal tonsil is_a: UBERON:0002372 ! tonsil is_a: UBERON:0012330 {source="cjm"} ! nasal-associated lymphoid tissue relationship: part_of UBERON:0001728 ! nasopharynx xref: SCTID:181199001 ! Entire adenoid synonym: "tonsilla pharyngea" RELATED LATIN [Wikipedia:Pharyngeal_tonsil] xref: http://upload.wikimedia.org/wikipedia/commons/b/be/Gray994-adenoid.png xref: UMLS:C0001428 [Term] id: UBERON:0001735 name: tonsillar ring def: "lymphoid tissue ring located in the pharynx and to the back of the oral cavity. The ring consists of (from superior to inferior): Pharyngeal tonsil (also known as 'adenoids' when infected) Tubal tonsil (where Eustachian tube opens in the nasopharynx) Palatine tonsils (commonly called 'the tonsils' in the vernacular, less commonly termed 'faucial tonsils') Lingual tonsils Some animals, but not humans, have one or two additional tonsils: Soft palate tonsil Paraepiglottic tonsil[WP]." [Wikipedia:Waldeyer's_ring] comment: see also FMA:79771 naso-pharyngeal lymphoid tissue subset: uberon_slim synonym: "oropharyngeal lymphoid tissue" EXACT [] synonym: "pharyngeal lymphatic ring" EXACT [] synonym: "pharyngeal lymphoid ring" EXACT [] synonym: "Waldeyer's ring" EXACT [] synonym: "Waldeyer's tonsillar ring" EXACT [] xref: FMA:55070 ! Tonsillar ring xref: MA:0000752 ! oropharyngeal lymphoid tissue xref: ncithesaurus:Waldeyers_Tonsillar_Ring ! Waldeyer's Tonsillar Ring is_a: UBERON:0001961 {source="MA"} ! mucosa-associated lymphoid tissue relationship: part_of UBERON:0001042 ! chordate pharynx synonym: "anulus lymphoideus pharyngis" EXACT LATIN [FMA:TA, FMA:55070] xref: SCTID:56411004 ! Entire Waldeyer's ring xref: UMLS:C0459892 [Term] id: UBERON:0003949 name: tubal tonsil def: "the lymph tissue associated with the pharyngeal opening of the auditory tube" [MP:0002386] synonym: "auditory tube lymph gland" EXACT [FMA:54975] synonym: "eustachian amygdala" EXACT [FMA:54975] synonym: "Gerlach's tonsil" EXACT [FMA:54975] synonym: "Gerlach's tubal tonsil" EXACT [FMA:54975] xref: FMA:54975 ! tubal tonsil is_a: UBERON:0002372 ! tonsil xref: SCTID:143319002 ! Entire tubal tonsil [Term] id: UBERON:0001734 name: uvula def: "Conic projection from the posterior edge of the middle of the soft palate, composed of connective tissue containing a number of racemose glands, and some muscular fibers. The uvula, hanging from the end of the soft palate, is responsible for the sound of snoring. Touching the uvula or the end of the soft palate evokes a strong gag reflex in most people." [Wikipedia:Palatine_uvula] comment: seeAlso - bifid uvula and cleft palate subset: uberon_slim synonym: "palatine uvula" EXACT [] synonym: "uvula of palate" EXACT [] xref: FMA:55022 ! Uvula xref: GAID:1285 ! uvula xref: ncithesaurus:Uvula xref: EFO:0001386 ! uvula xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/81/Tonsils_diagram.jpg/200px-Tonsils_diagram.jpg xref: MESH:A14.549.617.780.729 ! uvula is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001733 ! soft palate synonym: "uvula palatina" EXACT LATIN [FMA:TA, FMA:55022] xref: SCTID:362082005 ! Entire uvula palatina synonym: "uvula palatina" RELATED LATIN [Wikipedia:Palatine_uvula] xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Tonsils_diagram.jpg xref: UMLS:C0042173 [Term] id: UBERON:0001736 name: submandibular gland def: "The paired submandibular glands (submaxillary glands) are salivary glands located beneath the floor of the mouth. In humans, they account for 70% of the salivary volume and weigh about 15 grams. [WP,unvetted]." [Wikipedia:Submandibular_gland] comment: lobular, sexually dimorphic in mouse subset: uberon_slim synonym: "submaxillary gland" RELATED [] synonym: "submandibular salivary gland" EXACT [] xref: BTO:0001316 xref: FMA:55093 ! Submandibular gland xref: GAID:942 ! submandibular gland xref: VHOG:0000364 ! submandibular gland xref: MA:0001589 ! submandibular gland xref: ncithesaurus:Submandibular_Gland xref: EFO:0001387 ! submandibular gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/51/Illu_quiz_hn_02.jpg/200px-Illu_quiz_hn_02.jpg xref: EMAPA:18812 ! submandibular gland xref: MESH:A10.336.779.812 ! submandibular gland xref: EV:0100061 ! submandibular gland is_a: UBERON:0001829 ! major salivary gland relationship: develops_from UBERON:0006298 ! submandibular gland primordium relationship: in_lateral_side_of UBERON:0000165 ! mouth xref: SCTID:181235001 ! Entire submandibular gland synonym: "glandula submandibularis" RELATED LATIN [Wikipedia:Submandibular_gland] xref: http://upload.wikimedia.org/wikipedia/commons/5/51/Illu_quiz_hn_02.jpg property_value: external_definition "Either of two major salivary glands situated in the neck near the lower edge of each side of the mandible and emptying into the submandibular duct. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000364", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/submandibular+gland", source="http://bgee.unil.ch/"} property_value: homology_notes "The most common oral glands in mammals are the salivary glands. There are usually three primary pairs of salivary glands, named for their approximate positions: mandibular (submandibular or submaxillary), sublingual, and parotid.[well established][VHOG]" xsd:string {external_class="VHOG:0000364", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.525", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0001710 {source="FMA-abduced-lr"} ! lower jaw region xref: UMLS:C0038556 [Term] id: UBERON:0002334 name: submandibular duct def: "The submandibular duct (Wharton's duct, submaxillary duct) is one of the salivary ducts. It is about 5 cm. long, and its wall is much thinner than that of the parotid duct. It begins by numerous branches from the deep surface of the gland, and runs forward between the mylohyoideus, hyoglossus, and genioglossus, then between the sublingual gland and the genioglossus, and opens by a narrow orifice on the summit of a small at the side of the frenulum linguæ. On the hyoglossus it lies between the lingual and hypoglossal nerves, but at the anterior border of the muscle it is crossed laterally by the lingual nerve; the terminal branches of the lingual nerve ascend on its medial side. It drains saliva from the submandibular glands and sublingual glands to the sublingual caruncle at the base of the tongue. It was initially described by the English anatomist Thomas Wharton and sometimes referred to by his name. [WP,unvetted]." [Wikipedia:Submandibular_duct] comment: AO notes: FMA also has 'main submandibular duct' (FMA:59899) synonym: "submaxillary duct" RELATED [] synonym: "submandibular salivary duct" RELATED [] synonym: "Wharton's duct" RELATED INCONSISTENT [FMA:59899, Wikipedia:Submandibular_duct] subset: uberon_slim xref: FMA:86266 ! Submandibular duct xref: MA:0002698 ! submandibular duct xref: ncithesaurus:Submandibular_Duct ! Submandibular Duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Gray1024.png/200px-Gray1024.png xref: BTO:0004556 ! submandibular gland duct is_a: UBERON:0001837 ! duct of salivary gland relationship: part_of UBERON:0001736 ! submandibular gland relationship: channels_from UBERON:0001736 ! submandibular gland synonym: "ductus submaxillaris" RELATED LATIN [Wikipedia:Submandibular_duct] xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray1024.png xref: SCTID:181237009 ! Entire submaxillary duct xref: UMLS:C0227472 [Term] id: UBERON:0001737 name: larynx def: "Heterogeneous cluster that connects the pharynx to the tracheobronchial tree[FMA]." [Wikipedia:Larynx, FMA:55097] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: AAO:0000268 ! larynx xref: BTO:0001208 xref: EFO:0000838 ! larynx xref: FMA:55097 ! Larynx xref: GAID:108 ! larynx xref: galen:Larynx xref: VHOG:0001279 ! larynx xref: MA:0000414 ! larynx xref: MAT:0000187 ! larynx xref: MIAA:0000187 ! larynx xref: OpenCyc:Mx4rvViOnZwpEbGdrcN5Y29ycA xref: XAO:0003081 ! larynx xref: ncithesaurus:Larynx ! Larynx xref: OpenCyc:Mx4rvViOnZwpEbGdrcN5Y29ycA ! larynx xref: EMAPA:18333 ! larynx xref: MESH:A04.329 ! larynx xref: EV:0100039 ! larynx is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001557 ! upper respiratory tract relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium xref: EHDAA2:0004063 ! larynx xref: SCTID:181212004 ! Entire larynx xref: http://upload.wikimedia.org/wikipedia/commons/8/8a/Larynx_external_en.svg property_value: external_definition "Anatomical structure consisting of a narrowly triangular chamber supported by a series of semicircular cartilages in which part of the sound-production system is located.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000268", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "An anatomical cluster consisting of the epiglottus, the arytenoid cartilages, the thyroid cartilage, the cricoid cartilage and the muscles, membranes, and ligaments connecting them, and also of the mucosal covering these structures.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} property_value: homology_notes " (In anura) a dorsal pair of arytenoid cartilages (...), which support vocal cords, and a ventral pair (often fused) of cricoid cartilage (...). These cartilages are regarded as derivatives of posterior visceral arches of ancestors. Together they constitute the larynx, a structure characteristic of tetrapods. (...) (In mammals) Paired arytenoid cartilages help support and control the vocal cords. The cricoid cartilage is single. Two additional cartilages are present that are lacking in other vertebrates: a large ventral thyroid cartilage (...) and a cartilage in the epiglottis.[well established][VHOG]" xsd:string {external_class="VHOG:0001279", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.239-241", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "laryngeal" xsd:string xref: UMLS:C0023078 [Term] id: UBERON:0010212 ! laryngeal apparatus name: laryngeal apparatus def: "Apparatus located between the lungs and the buccal cavity. This apparatus is composed of a pair of arytenoid cartilages that are supported by the cricoid ring." [AAO:0000267] comment: Check this. See also UBERONREF:0000008 synonym: "laryngeal cartilage system" EXACT [EHDAA2:0000904] is_a: UBERON:0000467 {source="EHDAA2"} ! anatomical system relationship: part_of UBERON:0001737 {source="EHDAA2"} ! larynx relationship: composed_primarily_of UBERON:0001739 ! laryngeal cartilage relationship: part_of UBERON:0008895 ! splanchnocranium xref: EHDAA2:0000904 ! laryngeal cartilage system xref: AAO:0000267 ! laryngeal apparatus [Term] id: UBERON:0010221 name: laryngeal associated mesenchyme comment: Many sources say: thyroid cartilage from arch 4 other laryngeal cartilage (cricoid/arytenoid) from 6? is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: part_of UBERON:0001737 {source="EHDAA2"} ! larynx relationship: part_of UBERON:0008895 ! splanchnocranium relationship: develops_from UBERON:0002539 {source="Wikipedia"} ! pharyngeal arch relationship: has_developmental_contribution_from UBERON:0003115 {source="Wikipedia"} ! pharyngeal arch 4 relationship: has_developmental_contribution_from UBERON:0003117 {source="Wikipedia"} ! pharyngeal arch 6 xref: EHDAA2:0004085 ! laryngeal associated mesenchyme [Term] id: UBERON:0010213 ! laryngeal pre-cartilage condensation name: laryngeal pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0010212 {source="EHDAA2-abstracted"} ! laryngeal apparatus relationship: part_of UBERON:0008895 ! splanchnocranium relationship: develops_from UBERON:0010221 {source="EHDAA2-abstracted"} ! laryngeal associated mesenchyme [Term] id: UBERON:0010214 name: cricoid pre-cartilage condensation is_a: UBERON:0010213 ! laryngeal pre-cartilage condensation xref: EHDAA2:0000327 ! cricoid pre-cartilage condensation [Term] id: UBERON:0010219 name: thyroid pre-cartilage condensation is_a: UBERON:0010213 ! laryngeal pre-cartilage condensation xref: EHDAA2:0004088 ! thyroid pre-cartilage condensation [Term] id: UBERON:0001739 name: laryngeal cartilage def: "the cartilaginous structures that support the larynx." [MP:0002256] synonym: "cartilage of larynx" EXACT [FMA:55108] synonym: "larynx cartilage" EXACT [VHOG:0001550] synonym: "cartilagines laryngeales" EXACT PLURAL [] xref: EHDAA:8157 ! laryngeal cartilages xref: FMA:55108 ! Laryngeal cartilage xref: GAID:107 ! laryngeal cartilage xref: MA:0001758 ! larynx cartilage xref: ncithesaurus:Laryngeal_Cartilage xref: BTO:0003660 ! laryngeal cartilage xref: EMAPA:18697 ! laryngeal xref: MESH:A02.165.507 ! laryngeal cartilage xref: VHOG:0001550 ! larynx cartilage is_a: UBERON:0007844 {source="FMA"} ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0010212 ! laryngeal apparatus relationship: part_of UBERON:0008895 {source="UBERONREF:0000008"} ! splanchnocranium relationship: develops_from UBERON:0010213 ! laryngeal pre-cartilage condensation xref: SCTID:263482005 ! Entire laryngeal cartilage property_value: homology_notes " (In anura) a dorsal pair of arytenoid cartilages (...), which support vocal cords, and a ventral pair (often fused) of cricoid cartilage (...). These cartilages are regarded as derivatives of posterior visceral arches of ancestors. Together they constitute the larynx, a structure characteristic of tetrapods. (...) (In mammals) Paired arytenoid cartilages help support and control the vocal cords. The cricoid cartilage is single. Two additional cartilages are present that are lacking in other vertebrates: a large ventral thyroid cartilage (...) and a cartilage in the epiglottis.[well established][VHOG]" xsd:string {external_class="VHOG:0001550", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.239-241", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0023050 [Term] id: UBERON:0001738 name: thyroid cartilage def: "The thyroid cartilage is the largest of the nine cartilages that make up the laryngeal skeleton, the cartilage structure in and around the trachea that contains the larynx. It is composed of two plate-like laminae that fuse on the anterior side of the cartilage to form a peak, called the laryngeal prominence. This prominence is often referred to as the 'pomus Adamus' or 'Adam's apple'. The laryngeal prominence is more prominent in adult male than female because of the difference in the size of the angle: 90° in male and 120° in female. The lip of the thyroid cartilage just superior to the laryngeal prominence is called the superior thyroid notch, while the notch inferior to the thyroid angle is called the inferior thyroid notch. Its posterior border is elongated both inferiorly and superiorly to form the superior horn of thyroid cartilage and inferior horn of thyroid cartilage. [WP,unvetted]." [Wikipedia:Thyroid_cartilage] synonym: "cartilago thyroidea" RELATED [Wikipedia:Thyroid_cartilage] synonym: "pomus" RELATED [Wikipedia:Thyroid_cartilage] synonym: "pomus adamus" RELATED [Wikipedia:Thyroid_cartilage] synonym: "laryngeal prominence" RELATED [Wikipedia:Thyroid_cartilage] subset: uberon_slim xref: FMA:55099 ! Thyroid cartilage xref: GAID:112 ! thyroid cartilage xref: VHOG:0001365 ! thyroid cartilage xref: MA:0001764 ! thyroid cartilage xref: ncithesaurus:Thyroid_Cartilage ! Thyroid Cartilage xref: BTO:0003655 ! thyroid cartilage xref: EHDAA:9395 ! thyroid cartilage xref: EHDAA2:0002030 ! thyroid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8a/Larynx_external_en.svg/200px-Larynx_external_en.svg.png xref: EMAPA:18698 ! thyroid of cartilage of respiratory system xref: MESH:A02.165.507.870 ! thyroid cartilage is_a: UBERON:0001739 ! laryngeal cartilage relationship: develops_from UBERON:0010219 {source="EHDAA2"} ! thyroid pre-cartilage condensation relationship: part_of UBERON:0010212 {source="EHDAA2"} ! laryngeal apparatus xref: SCTID:263483000 ! Entire thyroid cartilage synonym: "cartilago thyroidea" RELATED LATIN [Wikipedia:Thyroid_cartilage] xref: http://upload.wikimedia.org/wikipedia/commons/8/8a/Larynx_external_en.svg property_value: external_definition "The largest cartilage of the larynx, having two broad processes that join anteriorly to form the Adam's apple. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001365", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/thyroid+cartilage", source="http://bgee.unil.ch/"} property_value: homology_notes "[In anura] a dorsal pair of arytenoid cartilages (...), which support vocal cords, and a ventral pair (often fused) of cricoid cartilage (...). These cartilages are regarded as derivatives of posterior visceral arches of ancestors. Together they constitute the larynx, a structure characteristic of tetrapods. (...) [In mammals] Paired arytenoid cartilages help support and control the vocal cords. The cricoid cartilage is single. Two additional cartilages are present that are lacking in other vertebrates: a large ventral thyroid cartilage (...) and a cartilage in the epiglottis.[well established][VHOG]" xsd:string {external_class="VHOG:0001365", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.239-241", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0040126 [Term] id: UBERON:0011623 ! horn of thyroid cartilage name: horn of thyroid cartilage synonym: "cornu of thyroid cartilage" EXACT [FMA:55300] synonym: "thyroid cartilage horn" EXACT [FMA:55300] xref: FMA:55300 ! horn of thyroid cartilage xref: SCTID:279518009 ! Entire cornu of thyroid cartilage is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0001738 ! thyroid cartilage [Term] id: UBERON:0011624 name: superior horn of thyroid cartilage def: "The superior horn of thyroid cartilage is long and narrow, directed upward, backward, and medialward, and ends in a conical extremity, which gives attachment to the lateral hyothyroid ligament." [Wikipedia:Superior_horn_of_thyroid_cartilage] synonym: "cornu superius (cartilago thyroidea)" EXACT [FMA:55294] synonym: "superior cornu of thyroid cartilage" EXACT [FMA:55294] synonym: "cornu superius cartilaginis thyroideae" EXACT LATIN [] is_a: UBERON:0011623 {source="FMA"} ! horn of thyroid cartilage xref: FMA:55294 ! Superior horn of thyroid cartilage xref: SCTID:279520007 ! Superior thyroid cornu [Term] id: UBERON:0011625 name: inferior horn of thyroid cartilage def: "The inferior horn of thyroid cartilage is short and thick; it is directed downward, with a slight inclination forward and medialward, and presents, on the medial side of its tip, a small oval articular facet for articulation with the side of the cricoid cartilage." [Wikipedia:Inferior_horn_of_thyroid_cartilage] synonym: "cornu inferius (cartilago thyroidea)" EXACT [FMA:55297] synonym: "cornu inferius cartilaginis thyroideae" EXACT LATIN [] is_a: UBERON:0011623 {source="FMA"} ! horn of thyroid cartilage xref: FMA:55297 ! Inferior horn of thyroid cartilage xref: SCTID:279521006 ! Inferior thyroid cornu [Term] id: UBERON:0002375 name: cricoid cartilage def: "The cricoid cartilage, or simply cricoid (from the Greek krikoeides meaning 'ring-shaped'), is the only complete ring of cartilage around the trachea. [WP,unvetted]." [Wikipedia:Cricoid_cartilage] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "cartilaginis cricoideae" RELATED PLURAL [Wikipedia:Cricoid_cartilage] synonym: "cartilago cricoidea" RELATED PLURAL [] synonym: "cricoid" RELATED [Wikipedia:Cricoid_cartilage] synonym: "cricoidea" RELATED [Wikipedia:Cricoid_cartilage] synonym: "krykoid cartilage" RELATED [Wikipedia:Cricoid_cartilage] synonym: "innominate cartilage" RELATED [VHOG:0001308] synonym: "cartilago cricoidea" EXACT LATIN [Wikipedia:Cricoid_cartilage] synonym: "cartilago cricotrachealis" RELATED [AAO:0000675] xref: AAO:0000675 ! cricoid_cartilage xref: FMA:9615 ! Cricoid cartilage xref: GAID:110 ! cricoid cartilage xref: VHOG:0001308 ! cricoid cartilage xref: MA:0001762 ! cricoid cartilage xref: ncithesaurus:Cricoid_Cartilage ! Cricoid Cartilage xref: EHDAA:9393 ! cricoid cartilage xref: EHDAA2:0000326 ! cricoid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/54/Gray1194.png/200px-Gray1194.png xref: EMAPA:18696 ! cricoid xref: MESH:A02.165.507.211 ! cricoid cartilage is_a: UBERON:0001739 {source="MA"} ! laryngeal cartilage is_a: UBERON:0001994 {source="Wikipedia"} ! hyaline cartilage relationship: develops_from UBERON:0010214 {source="EHDAA2"} ! cricoid pre-cartilage condensation xref: SCTID:263484006 ! Entire cricoid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/5/54/Gray1194.png property_value: external_definition "Cartilaginous ring that provides support for the arytenoid cartilages. Its ventral part is bent posteriorly to form a V.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000675", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The ringlike cartilage forming the caudal part of the larynx. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001308", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/cricoid+cartilage", source="http://bgee.unil.ch/"} property_value: homology_notes " (In anura) a dorsal pair of arytenoid cartilages (...), which support vocal cords, and a ventral pair (often fused) of cricoid cartilage (...). These cartilages are regarded as derivatives of posterior visceral arches of ancestors. Together they constitute the larynx, a structure characteristic of tetrapods. (...) (In mammals) Paired arytenoid cartilages help support and control the vocal cords. The cricoid cartilage is single. Two additional cartilages are present that are lacking in other vertebrates: a large ventral thyroid cartilage (...) and a cartilage in the epiglottis.[well established][VHOG]" xsd:string {external_class="VHOG:0001308", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.239-241", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0010323 [Term] id: UBERON:0001740 name: arytenoid cartilage def: "The arytenoid cartilages are a pair of small three-sided pyramids which form part of the larynx, to which the vocal cords are attached. Each is pyramidal in form, and has three surfaces, a base, and an apex. [WP,unvetted]." [Wikipedia:Arytenoid_cartilage] synonym: "cartilago arytenoidea" RELATED [] synonym: "cartilago arytaenoidea" RELATED [AAO:0000674] synonym: "arytenoids" RELATED [Wikipedia:Arytenoid_cartilage] synonym: "arytenoid" EXACT [EMAPA:18695] subset: uberon_slim xref: AAO:0000674 ! arytenoid_cartilage xref: FMA:55109 ! Arytenoid cartilage xref: GAID:109 ! arytenoid cartilage xref: MA:0001759 ! arytenoid cartilage xref: ncithesaurus:Arytenoid_Cartilage ! Arytenoid Cartilage xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fa/Gray950.png/200px-Gray950.png xref: EMAPA:18695 ! arytenoid xref: MESH:A02.165.507.083 ! arytenoid cartilage is_a: UBERON:0001739 ! laryngeal cartilage relationship: develops_from UBERON:0010220 {source="cjm"} ! arytenoid pre-cartilage condensation relationship: in_lateral_side_of UBERON:0001737 ! larynx xref: SCTID:264446005 ! Entire arytenoid cartilage xref: EMAPA:17977 ! arytenoid cartilage xref: EMAPA:18695 ! arytenoid synonym: "cartilagines arytenoidea" RELATED LATIN [Wikipedia:Arytenoid_cartilage] xref: http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray950.png property_value: external_definition "Paired, anteroposteriorly elongated cartilages that are associated with the vocal cords. These cartilages are medially separated and hemispherical, and their concave side faces ventromedially.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000674", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0003943 [Term] id: UBERON:0010220 ! arytenoid pre-cartilage condensation name: arytenoid pre-cartilage condensation is_a: UBERON:0010213 ! laryngeal pre-cartilage condensation relationship: develops_from UBERON:0010215 {source="EHDAA2"} ! arytenoid swellings synonym: "arytenoid swelling pre-cartilage condensation" EXACT [EMAPA:17387] xref: EHDAA2:0000144 ! arytenoid pre-cartilage condensation xref: EMAPA:17387 ! arytenoid swelling pre-cartilage condensation xref: VHOG:0000998 ! arytenoid pre-cartilage condensation [Term] id: UBERON:0010215 name: arytenoid swellings def: "paired primordial elevations, on either side of the embryonic larynx, within which the arytenoid cartilages are formed" [http://www.medilexicon.com/medicaldictionary.php?t=87317] comment: AO notes - EHDAA2 and EMAPA appear to be inconsistent is_a: UBERON:0005856 {source="EHDAA2"} ! mesenchymal condensation relationship: part_of UBERON:0010212 {source="EHDAA2"} ! laryngeal apparatus relationship: develops_from UBERON:0010221 {source="EHDAA2"} ! laryngeal associated mesenchyme xref: EHDAA2:0000146 ! arytenoid swellings [Term] id: UBERON:0001741 name: corniculate cartilage def: "The corniculate cartilages (cartilages of Santorini) are two small conical nodules consisting of yellow elastic cartilage, which articulate with the summits of the arytenoid cartilages and serve to prolong them posteriorly and medially. They are situated in the posterior parts of the aryepiglottic folds of mucous membrane, and are sometimes fused with the arytenoid cartilages. [WP,unvetted]." [Wikipedia:Corniculate_cartilages] subset: uberon_slim synonym: "Santorini's cartilage" EXACT [] synonym: "cartilage of Santorini" EXACT [] synonym: "cartilagines corniculata" EXACT LATIN [Wikipedia:Corniculate_cartilage] xref: FMA:55110 ! Corniculate cartilage xref: MA:0001885 ! corniculate cartilage xref: ncithesaurus:Corniculate_Cartilage ! Corniculate Cartilage xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/56/Gray952.png/200px-Gray952.png is_a: UBERON:0001996 {source="MA"} ! elastic cartilage relationship: part_of UBERON:0001737 {source="FMA"} ! larynx relationship: part_of UBERON:0008895 ! splanchnocranium relationship: has_developmental_contribution_from UBERON:0003117 ! pharyngeal arch 6 xref: SCTID:278989005 ! Entire corniculate cartilage xref: http://upload.wikimedia.org/wikipedia/commons/5/56/Gray952.png xref: UMLS:C0225556 [Term] id: UBERON:0011157 name: cuneiform cartilage def: "The cuneiform cartilages of the larynx are two small, elongated pieces of yellow elastic cartilage, placed one on either side, in the aryepiglottic fold, where they give rise to small whitish elevations on the surface of the mucous membrane, just in front of the arytenoid cartilages." [Wikipedia:Cuneiform_cartilages] comment: AAO def: "Independent cartilage that may occur dorsal or anterior to the prominentiae apicales dorsales of the arytenoid cartilages." synonym: "cartilagines cuneiformes" RELATED LATIN [Wikipedia:Cuneiform_cartilages] synonym: "cartilage of Morgagni" EXACT [FMA:55111] synonym: "cartilage of Wrisberg" EXACT [FMA:55111] synonym: "cartilago apicalis intermedia" RELATED [AAO:0000690] synonym: "cartilago apicalis seu cartilago Santoriniana" RELATED [AAO:0000690] synonym: "Wrisbergi cartilage" EXACT [AAO:0000690] is_a: UBERON:0001996 {source="Wikipedia"} ! elastic cartilage is_a: UBERON:0001739 {source="FMA"} ! laryngeal cartilage xref: FMA:55111 ! cuneiform cartilage xref: SCTID:264456009 ! Entire cuneiform cartilage xref: AAO:0000690 ! wrisbergi cartilage xref: http://upload.wikimedia.org/wikipedia/commons/5/50/Gray956.png property_value: external_definition "Independent cartilage that may occur dorsal or anterior to the prominentiae apicales dorsales of the arytenoid cartilages.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000690", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0001742 name: epiglottic cartilage def: "the most superior of the laryngeal cartilages, which is found at the root of the tongue and folds back over the entrance to the larynx during swallowing." [MP:0002259] comment: AO notes: laryngeal cartilage in MP subset: uberon_slim xref: FMA:55112 ! Epiglottic cartilage xref: MA:0001763 ! epiglottic cartilage xref: ncithesaurus:Epiglottic_Cartilage ! Epiglottic Cartilage is_a: UBERON:0001996 ! elastic cartilage is_a: UBERON:0001739 ! laryngeal cartilage relationship: part_of UBERON:0000388 ! epiglottis xref: SCTID:278990001 ! Entire epiglottic cartilage xref: UMLS:C0458526 [Term] id: UBERON:0000388 ! epiglottis name: epiglottis def: "a flap of elastic cartilage tissue covered with a mucous membrane, attached to the entrance of the larynx. It projects obliquely upwards behind the tongue and the hyoid bone, pointing dorsally." [Wikipedia:Epiglottis] comment: Editor note: refine definition to better distinguish cartilage from the whole structure xref: BTO:0001628 xref: FMA:55130 ! Epiglottis xref: ncithesaurus:Epiglottis ! Epiglottis xref: GAID:111 ! epiglottis xref: OpenCyc:Mx4rvVjxE5wpEbGdrcN5Y29ycA ! epiglottis xref: EMAPA:18289 ! epiglottis xref: MESH:A02.165.507.411 ! epiglottis is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001051 ! hypopharynx relationship: develops_from UBERON:0003115 {source="EHDAA2"} ! pharyngeal arch 4 relationship: never_in_taxon NCBITaxon:8782 ! Aves xref: EHDAA2:0004081 ! epiglottis xref: SCTID:245502004 ! Entire epiglottis xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Gray958.png property_value: has_relational_adjective "epiglottal" xsd:string xref: UMLS:C0014540 [Term] id: UBERON:0013165 name: epiglottic vallecula def: "A depression in front of the epiglottis, in which food is temporarily gathered as the animal chews." [Wikipedia:Epiglottic_vallecula, ISBN10:0073040584] synonym: "vallecula of epiglottis" EXACT [FMA:55037] synonym: "vallecula of epiglottis" EXACT [] synonym: "vallecula epiglottica" EXACT LATIN [] synonym: "vallecula" BROAD [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000341 ! throat xref: FMA:55037 ! epiglottic vallecula xref: SCTID:276955003 ! Entire vallecula of epiglottis property_value: external_definition "Region of surface of viscerocranial mucosa, which is a depression located between the median and lateral glosso-epiglottic folds. Examples: There are only two instances, right and left epiglottic valleculas[FMA:55037]." xsd:string {source="FMA:55037"} [Term] id: UBERON:0013166 name: vallecula of cerebellum def: "On the upper surface of the cerebellum the vermis is elevated above the level of the hemispheres, but on the under surface it is sunk almost out of sight in the bottom of a deep depression between them; this depression is called the vallecula of the cerebellum, and lodges the posterior part of the medulla oblongata." [Wikipedia:Vallecula_of_cerebellum] synonym: "vallecula cerebelli" EXACT LATIN [FMA:75267] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001896 ! medulla oblongata xref: FMA:75267 ! vallecula cerebelli xref: ncithesaurus:Vallecula ! vallecula [Term] id: UBERON:0001743 name: ligament of larynx def: "A ligament that is part of a larynx and connexts the cartilages of the larynx" [http://education.yahoo.com/reference/gray/subjects/subject/236] synonym: "laryngeal ligament" EXACT [] synonym: "larynx ligament" EXACT [MA:0001755] xref: FMA:55131 ! Ligament of larynx xref: MA:0001755 ! larynx ligament xref: ncithesaurus:Laryngeal_Ligament ! Laryngeal Ligament is_a: UBERON:0008845 {source="FMA"} ! nonskeletal ligament intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001737 ! larynx xref: SCTID:279508004 ! Laryngeal ligament xref: UMLS:C0458519 [Term] id: UBERON:0001730 name: extrinsic ligament of larynx synonym: "laryngeal extrinsic ligament" EXACT [] xref: FMA:54921 ! Extrinsic ligament of larynx xref: MA:0001756 ! laryngeal extrinsic ligament is_a: UBERON:0001743 ! ligament of larynx xref: SCTID:279550004 ! Extrinsic laryngeal ligament [Term] id: UBERON:0006325 name: laryngeal intrinsic ligament synonym: "intrinsic ligament of larynx" EXACT [FMA:72058] xref: FMA:72058 ! Intrinsic ligament of larynx xref: MA:0001757 ! laryngeal intrinsic ligament is_a: UBERON:0001743 ! ligament of larynx xref: SCTID:279557001 ! Intrinsic laryngeal ligament [Term] id: UBERON:0011311 name: hyoepiglottic ligament def: "an elastic band connecting the anterior surface of the epiglottis to the upper border of the body of the hyoid bone." [Wikipedia:Hyoepiglottic_ligament] synonym: "hyo-epiglottic ligament" EXACT [FMA:55227] synonym: "igamentum hyoepiglotticum" EXACT LATIN [Wikipedia:Hyoepiglottic_ligament] is_a: UBERON:0001730 {source="FMA"} ! extrinsic ligament of larynx relationship: connects UBERON:0000388 ! epiglottis relationship: connects UBERON:0003999 ! hyoid bone body relationship: part_of UBERON:0001737 ! larynx xref: FMA:55227 ! hyo-epiglottic ligament xref: SCTID:279552007 ! Entire hyoepiglottic ligament xref: ncithesaurus:Hyoepiglottic_Ligament ! hyoepiglottic ligament xref: UMLS:C0225515 [Term] id: UBERON:0011312 name: hyoepiglottic muscle comment: Developed in mammals other than human. TODO: add relationship to hyoepiglottic ligament. synonym: "hyo-epiglottic muscle" EXACT [] synonym: "hyoepiglottus" EXACT [] synonym: "hyoepiglotticus" EXACT [] is_a: UBERON:0001568 ! muscle of larynx relationship: attaches_to UBERON:0000388 ! epiglottis relationship: attaches_to UBERON:0003999 ! hyoid bone body [Term] id: UBERON:0013167 name: cricopharyngeal ligament def: "Laryngeal ligament that connects the cricoid cartilage to the pharynx[WP,modified]" [Wikipedia:Cricopharyngeal_ligament] synonym: "ligamentum cricopharyngeum" EXACT LATIN [Wikipedia:Cricopharyngeal_ligament] synonym: "crico-pharyngeal ligament" EXACT [] is_a: UBERON:0001730 {source="FMA"} ! extrinsic ligament of larynx intersection_of: UBERON:0001743 ! ligament of larynx intersection_of: connects UBERON:0001042 ! chordate pharynx intersection_of: connects UBERON:0002375 ! cricoid cartilage xref: FMA:55260 ! cricopharyngeal ligament xref: SCTID:172455006 ! Entire cricopharyngeal ligament [Term] id: UBERON:0013168 name: thyroepiglottic ligament def: "Laryngeal ligament that connects the epiglottis to the thyroid cartilage[WP,modified]" [Wikipedia:Thyroepiglottic_ligament] synonym: "thyroepiglottic ligament" EXACT [FMA:55230] synonym: "ligamentum thyroepiglotticum" EXACT LATIN [] is_a: UBERON:0006325 {source="FMA"} ! laryngeal intrinsic ligament intersection_of: UBERON:0001743 ! ligament of larynx intersection_of: connects UBERON:0001742 ! epiglottic cartilage intersection_of: connects UBERON:0001738 ! thyroid cartilage xref: FMA:55230 ! thyro-epiglottic ligament xref: SCTID:279562000 ! Entire thyroepiglottic ligament xref: ncithesaurus:Thyroepiglottic_Ligament ! thyroepiglottic ligament xref: UMLS:C0225514 [Term] id: UBERON:0013169 name: vestibular ligament def: "The vestibular fold is a fibroelastic band which passes from the ventral margin of the cuneiform cartilage to the cranial dorsal surface of the thyroid cartilage. It forms the support for the free edge of the vestibular fold." [MURDOCH:2193, Wikipedia:Vestibular_ligament] synonym: "ligamentum vestibulare" EXACT LATIN [Wikipedia:Vestibular_ligament] synonym: "ventricular ligament" EXACT [Wikipedia:Vestibular_ligament] synonym: "vestibular ligament of larynx" EXACT [] is_a: UBERON:0006325 {source="FMA"} ! laryngeal intrinsic ligament intersection_of: UBERON:0001743 ! ligament of larynx intersection_of: connects UBERON:0011157 ! cuneiform cartilage intersection_of: connects UBERON:0001738 ! thyroid cartilage xref: FMA:64147 ! vestibular ligament xref: SCTID:279561007 ! Entire vestibular ligament of larynx [Term] id: UBERON:0013170 name: cricoarytenoid ligament def: "Laryngeal ligament that connects the cricoid and arytenoid cartilages[WP,modified]" [Wikipedia:Cricoarytenoid_ligament] is_a: UBERON:0001730 {source="FMA"} ! extrinsic ligament of larynx intersection_of: UBERON:0001743 ! ligament of larynx intersection_of: connects UBERON:0001740 ! arytenoid cartilage intersection_of: connects UBERON:0002375 ! cricoid cartilage synonym: "crico-arytenoid ligament" EXACT [FMA:55261] synonym: "ligamentum cricoaryteneoideum" EXACT LATIN [Wikipedia:Cricoarytenoid_ligament] xref: FMA:55261 ! crico-arytenoid ligament xref: SCTID:172533001 ! Entire posterior cricoarytenoid ligament [Term] id: UBERON:0013171 name: cricothyroid ligament def: "This attaches the caudal border of the thyroid cartilage to the ventral arch of the cricoid cartilage. Its sheetlike ventral portion is sometimes referred to as the cricothyroid membrane. Being elastic, it 'balances' movement at the hinge-like cricothyroid joint and determines the resting position of the larynx when the muscles are relaxed[MURDOCH]. The cricothyroid ligament is the larger part of the laryngeal membrane, continuing inferiorly as a median or anterior part and twin lateral ligaments. The median cricothyroid ligament is a flat band of white tissue joining the cricoid and thyroid cartilages, while the lateral cricothyroid ligament is also known as the cricothyroid membrane (also called conus elasticus)." [MURDOCH:483, Wikipedia:Cricothyroid_ligament] synonym: "crico-thyroid ligament" EXACT [] synonym: "ligamentum cricothyreoideum" EXACT LATIN [Wikipedia:Cricothyroid_ligament] intersection_of: UBERON:0001743 ! ligament of larynx intersection_of: connects UBERON:0001738 ! thyroid cartilage intersection_of: connects UBERON:0002375 ! cricoid cartilage xref: FMA:55233 ! cricothyroid ligament xref: SCTID:279558006 ! Entire cricothyroid ligament xref: ncithesaurus:Cricothyroid_Ligament ! cricothyroid ligament xref: UMLS:C0225542 [Term] id: UBERON:0013172 name: cricotracheal ligament def: "The cricotracheal ligament connects the cricoid cartilage with the first ring of the trachea[WP]. The caudal border of the cricoid cartilage is joined to the first ring of the trachea by this ligament. It is an extrinsic laryngeal ligament. It resembles the fibrous membrane which connects the cartilaginous rings of the trachea to each other." [MURDOCH:486, Wikipedia:Cricotracheal_ligament] is_a: UBERON:0001730 {source="FMA"} ! extrinsic ligament of larynx intersection_of: UBERON:0001743 ! ligament of larynx intersection_of: connects UBERON:0003604 ! trachea cartilage intersection_of: connects UBERON:0002375 ! cricoid cartilage xref: FMA:55259 ! cricotracheal ligament xref: SCTID:279553002 ! Entire cricotracheal ligament xref: ncithesaurus:Cricotracheal_Ligament ! cricotracheal ligament xref: UMLS:C0225543 [Term] id: UBERON:0001746 name: fibrous capsule of thyroid gland comment: This class was created automatically from a combination of ontologies synonym: "thyroid capsule" EXACT [] synonym: "thyroid gland capsule" EXACT [] xref: FMA:55513 ! Fibrous capsule of thyroid gland xref: MA:0002675 ! thyroid gland capsule xref: ncithesaurus:Thyroid_Gland_Capsule ! Thyroid Gland Capsule is_a: UBERON:0003893 ! capsule relationship: part_of UBERON:0002046 ! thyroid gland xref: SCTID:176859009 ! Entire thyroid capsule xref: UMLS:C0229575 [Term] id: UBERON:0001747 name: parenchyma of thyroid gland def: "A parenchyma that is part of a thyroid follicle [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "thyroid gland parenchyma" EXACT [] synonym: "parenchyma of thyroid" EXACT [OBOL:accepted] synonym: "parenchyma of thyroid follicle" EXACT [OBOL:automatic] synonym: "parenchyma of thyroid gland follicle" EXACT [OBOL:automatic] synonym: "thyroid follicle parenchyma" EXACT [OBOL:automatic] synonym: "thyroid gland follicle parenchyma" EXACT [OBOL:automatic] synonym: "thyroid parenchyma" EXACT [OBOL:accepted] xref: FMA:55515 ! Parenchyma of thyroid gland xref: MA:0000730 ! thyroid gland parenchyma xref: BTO:0004579 ! parenchyma of thyroid gland is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002046 ! thyroid gland relationship: part_of UBERON:0002046 ! thyroid gland relationship: has_part CL:0000570 {source="FMA"} ! parafollicular cell relationship: has_part CL:0002258 {source="FMA"} ! thyroid follicular cell xref: SCTID:371402001 ! Structure of parenchyma of thyroid [Term] id: UBERON:0001748 name: capsule of parathyroid gland comment: This class was created automatically from a combination of ontologies synonym: "parathyroid gland capsule" EXACT [] xref: FMA:55566 ! Capsule of parathyroid gland xref: MA:0002676 ! parathyroid gland capsule xref: ncithesaurus:Parathyroid_Gland_Capsule ! Parathyroid Gland Capsule is_a: UBERON:0003893 ! capsule intersection_of: UBERON:0003893 ! capsule intersection_of: surrounds UBERON:0001132 ! parathyroid gland relationship: surrounds UBERON:0001132 ! parathyroid gland def: "A capsule that surrounds a parathyroid gland." [OBOL:automatic] xref: UMLS:C0927176 [Term] id: UBERON:0001749 name: parenchyma of parathyroid gland def: "A parenchyma that is part of a parathyroid gland [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "parathyroid gland parenchyma" EXACT [] synonym: "parathyroid parenchyma" EXACT [OBOL:automatic] synonym: "parenchyma of parathyroid" EXACT [OBOL:automatic] xref: FMA:55569 ! Parenchyma of parathyroid gland xref: MA:0002677 ! parathyroid gland parenchyma is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0001132 ! parathyroid gland relationship: part_of UBERON:0001132 ! parathyroid gland relationship: has_part CL:0000446 {source="FMA"} ! chief cell of parathyroid gland relationship: has_part CL:0002199 {source="FMA"} ! oxyphil cell of parathyroid gland [Term] id: UBERON:0011587 name: pre-dentine def: "Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix[VSAO]." [VSAO:0000071] synonym: "pre-dentine tissue" EXACT [VSAO:curator] synonym: "predentine tissue" EXACT [VSAO:curator] synonym: "predentin" EXACT [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360947] is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue relationship: develops_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest relationship: develops_from UBERON:0000924 ! ectoderm relationship: secreted_by CL:0000060 {source="text definition"} ! odontoblast xref: VSAO:0000071 ! pre-dentine xref: XAO:0004052 ! pre-dentine [Term] id: UBERON:0001751 name: dentine def: "Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular[VSAO]." [VSAO:0000069, Wikipedia:Dentin] comment: Dentine is found in the fossil record as early as the late Cambrian, in fish, where it may have had a role in electrochemical sensing of the environment as well as assisting in defense[WP]. Editors note: note the asserted dual is_a parentage, as dentine is both skeletal tissue and a substance subset: uberon_slim subset: vertebrate_core synonym: "dentin" EXACT [MA:0002542] synonym: "predentin" NARROW [GO:0070468] synonym: "dentine of tooth" EXACT [] xref: FMA:55628 ! Dentine xref: GAID:1272 ! dentin xref: MA:0002542 ! dentin xref: TAO:0005143 ! dentine xref: ZFA:0005143 ! dentine xref: ncithesaurus:Dentin ! Dentin xref: BTO:0003453 ! dentin xref: MESH:A14.254.900.280 ! dentin xref: VSAO:0000069 ! dentine is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue is_a: UBERON:0001973 ! substance of tooth relationship: develops_from UBERON:0011587 {source="VSAO"} ! pre-dentine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: SCTID:362112004 ! Entire dentin xref: XAO:0004051 ! dentine xref: VHOG:0001589 ! dentine property_value: external_definition "Mineralized collagen containing substance that forms the tooth structure.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005143", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Dentine is a bona fide vertebrate novelty, and dentine-secreting odontoblasts represent a cell type that is exclusively derived from the neural crest.[well established][VHOG]" xsd:string {external_class="VHOG:0001589", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2012.01495.x Hall BK\, Gillis JA\, Incremental evolution of the neural crest\, neural crest cells and neural crest-derived skeletal tissues. J Anat (2012)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "dentinal" xsd:string xref: UMLS:C0011429 [Term] id: UBERON:0011588 name: pre-enamel def: "Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix." [VSAO:0000066] synonym: "pre-enamel tissue" EXACT [VSAO:curator] synonym: "preenamel tissue" EXACT [VSAO:curator] is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue xref: VSAO:0000066 ! pre-enamel xref: XAO:0004202 ! pre-enamel relationship: secreted_by CL:0000059 ! ameloblast [Term] id: UBERON:0001752 name: enamel def: "A dentine-like hypermineralized substance that covers the tooth tip. Enamel's primary mineral is hydroxylapatite, which is a crystalline calcium phosphate. Unlike dentin and bone, enamel does not contain collagen. Instead, it has two unique classes of proteins called amelogenins and enamelins[WP]." [Wikipedia:Enamel_organ, ZFIN:curator] comment: AO notes: part_of tooth enamel organ in MA. Editor notes: current classification under substance of tooth may be turned into taxon GCI (e.g. sharks have enamel in dermal denticles) subset: uberon_slim subset: vertebrate_core synonym: "enamel of tooth" EXACT [] synonym: "enameloid" RELATED [] synonym: "tooth enamel" EXACT [] synonym: "enamel tissue" EXACT [VSAO:curator] xref: FMA:55629 ! Enamel xref: MA:0002543 ! enamel xref: ncithesaurus:Enamel ! Enamel xref: BTO:0001844 ! tooth enamel xref: MESH:A14.254.900.255 ! dental enamel xref: VSAO:0000065 ! enamel is_a: UBERON:0001973 {source="FMA"} ! substance of tooth is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue relationship: develops_from UBERON:0011588 {source="VSAO"} ! pre-enamel relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: composed_primarily_of CHEBI:52255 {source="Wikipedia:ENAM", proportion="85"} ! hydroxylapatite relationship: never_in_taxon NCBITaxon:9359 {source="PMID:19730686"} ! Dasypodidae relationship: never_in_taxon NCBITaxon:9816 {source="PMID:19730686"} ! Orycteropodidae xref: SCTID:362113009 ! Entire enamel xref: XAO:0004198 ! enamel xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Enamelorgan11-17-05.jpg property_value: external_definition "Skeletal tissue that consists of an avascular, noncollagenous, hypermineralized matrix that is deposited by ameloblasts that are excluded from the matrix. Enamel develops from organic pre-enamel tissue that is replaced by a largely inorganic matrix.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000065", date_retrieved="2012-08-14", source="PSPUB:0000170"} xref: UMLS:C0011350 [Term] id: UBERON:0011688 name: pre-enameloid def: "Odontoid tissue that is avascular non-mineralized matrix that is deposited by odontoblasts and ameloblasts that are excluded from the matrix." [VSAO:0000114] synonym: "non-mineralized enameloid tissue" EXACT [VSAO:curator] is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue xref: VSAO:0000114 ! pre-enameloid xref: XAO:0004203 ! pre-enameloid [Term] id: UBERON:0011692 name: enameloid def: "Skeletal tissue that is hypermineralized and aprismatic and deposited by a combination of ameloblasts and odontoblasts that are excluded from the matrix. Enameloid develops from pre-enameloid tissue." [VSAO:0000113] synonym: "bitypic enamel" EXACT [VSAO:curator] synonym: "durodentine" EXACT [VSAO:curator] synonym: "enameloid tissue" EXACT [VSAO:curator] synonym: "vitrodentine" EXACT [VSAO:curator] is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue relationship: develops_from UBERON:0011688 {source="VSAO"} ! pre-enameloid relationship: part_of UBERON:0001091 {source="ZFA"} ! calcareous tooth xref: VSAO:0000113 ! enameloid xref: VHOG:0001565 ! enameloid xref: XAO:0004199 ! enameloid xref: ZFA:0005142 ! enameloid [Term] id: UBERON:0001753 name: cementum def: "A bone-like mineralized tissue secreted by cementoblasts on the surface of root dentine or, in some animals, crown enamel[Diekwisch 2001]. Substance of tooth produced by cementoblasts; surrounds the dentine of the root of the tooth[FMA]. a specialized calcified substance covering the root of a tooth. Cementum is excreted by cells called cementoblasts within the root of the tooth and is thickest at the root apex. Its coloration is yellowish and it is softer than enamel and dentin due to being less mineralized[WP]." [Wikipedia:Cementum] comment: Cementum, the supporting tissue that anchors mammalian and crocodylian teeth into their sockets, differs among species and can have features of dentine, of bone, and of calcified cartilage, as well as unique features. Cementum is deposited by cementoblasts onto existing dentine. As in bone and dentine, cementoblasts produce an organic matrix, the main constituent of which is collagen type I (Bosshardt, 2005), but cementum, dentine, and bone also share a number of important noncollagenous matrix components such as osteopontin, osteocalcin, bone sialoprotein, a2-HS- glycoprotein, dentine matrix protein, dentine sialoprotein, and den- tine phosphoprotein (McKee et al., 1996; Bosshardt, 2005). it has been argued that in all rodents and ruminants, cementum is a form of calcified cartilage[H&W] synonym: "cement" EXACT [] synonym: "cement of tooth" EXACT [] synonym: "cementum" EXACT [] synonym: "cementum of tooth" EXACT [] xref: FMA:55630 ! Cement xref: MA:0002541 ! cementum xref: ncithesaurus:Cementum ! Cementum xref: BTO:0002525 ! cementum xref: MESH:A14.254.646.267 ! dental cementum xref: VSAO:0000062 ! cementum is_a: UBERON:0001973 ! substance of tooth is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue relationship: has_developmental_contribution_from UBERON:0008969 {source="PMID:19767574", source="Wikipedia"} ! dental follicle xref: SCTID:362114003 ! Entire cementum xref: XAO:0004196 ! cementum xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/The_Periodontium.jpg property_value: external_definition "Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000062", date_retrieved="2012-08-14", source="PSPUB:0000170"} synonym: "bone of attachment" RELATED [VSAO:0000062] xref: UMLS:C0011343 [Term] id: UBERON:0001754 name: dental pulp def: "the part in the center of a tooth made up of living soft tissue and cells called odontoblasts[WP]." [Wikipedia:Dental_pulp] subset: uberon_slim subset: vertebrate_core synonym: "pulp of tooth" EXACT [] synonym: "tooth pulp" EXACT [ZFA:0005141] synonym: "dental pulp cell" RELATED [BTO:0000339] xref: BTO:0000339 xref: FMA:55631 ! Dental pulp xref: GAID:1270 ! dental pulp xref: VHOG:0001469 ! dental pulp xref: MA:0001599 ! dental pulp xref: ncithesaurus:Dental_Pulp ! Dental Pulp xref: ZFA:0005141 ! tooth pulp xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Tooth_Section.svg/200px-Tooth_Section.svg.png xref: MESH:A14.254.900.260 ! dental pulp is_a: UBERON:0011825 {source="FMA"} ! loose connective tissue relationship: part_of UBERON:0001091 ! tooth relationship: has_part CL:0000060 ! odontoblast relationship: develops_from UBERON:0001763 {source="ZFA"} ! odontogenic papilla xref: SCTID:362110007 ! Entire pulp of tooth xref: TAO:0005141 ! tooth pulp property_value: external_definition "Material in the center of the dentine of the mature tooth. In secondary teeth the pulp contains blood vessels and odontoblast.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005141", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "The oral cavity of vertebrates is generally thought to arise as an ectodermal invagination. Consistent with this, oral teeth are proposed to arise exclusively from ectoderm, contributing to tooth enamel epithelium, and from neural crest derived mesenchyme, contributing to dentin and pulp (reference 1); Teeth and tooth-like structures, together named odontodes, are repeated organs thought to share a common evolutionary origin. These structures can be found in gnathostomes at different locations along the body: oral teeth in the jaws, teeth and denticles in the oral-pharyngeal cavity, and dermal denticles on elasmobranch skin (reference 2).[uncertain][VHOG]" xsd:string {external_class="VHOG:0001469", ontology="VHOG", source="DOI:10.1038/nature07304 Soukup V\, Epperlein HH\, Horacek I\, Cerny R\, Dual epithelial origin of vertebrate oral teeth. Nature (2008)\, DOI:10.1186/1471-2148-11-307 The homology of odontodes in gnathostomes: insights from Dlx gene expression in the dogfish\, Scyliorhinus canicula. BMC Evolutionary Biology (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0011399 [Term] id: UBERON:0001756 name: middle ear def: "The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)[GO]." [GO:0042474, Wikipedia:Middle_ear] subset: uberon_slim synonym: "auris media" RELATED [BTO:0002099] xref: EHDAA:5693 ! middle ear xref: FMA:56513 ! Middle ear xref: GAID:165 ! middle ear xref: VHOG:0000312 ! middle ear xref: MA:0000253 ! middle ear xref: MAT:0000146 ! middle ear xref: MIAA:0000146 ! middle ear xref: ncithesaurus:Middle_Ear xref: NIF_GrossAnatomy:birnlex_1695 ! Middle ear xref: OpenCyc:Mx4rvbw1j5wpEbGdrcN5Y29ycA xref: XAO:0000191 ! middle ear xref: BTO:0002099 ! middle ear xref: OpenCyc:Mx4rvbw1j5wpEbGdrcN5Y29ycA ! middle ear xref: EHDAA2:0001181 ! middle ear xref: EMAPA:17000 ! middle ear xref: MESH:A09.246.397 ! middle ear xref: EV:0100357 ! middle ear is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001690 ! ear xref: AAO:0011065 ! middle ear xref: SCTID:181185000 ! Entire middle ear synonym: "auris media" RELATED LATIN [Wikipedia:Middle_ear] property_value: external_definition "The intermediate portion of the ear which consists of a small air-filled and membrane-lined chamber. It is lodged in the temporal bone and continues with the nasopharynx through the Eustachian tube. It is separated from the external ear by the tympanic membrane and from the inner ear by the fenestrae. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000312", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The tympanic cavity and auditory tube of an amniote develop from the first embryonic pharyngeal pouch, so they are homologous to the first gill pouch, or spiracle, of a fish. We are uncertain whether this homology strictly applies to the middle ear cavity and auditory tube of lissamphibians, which show certain peculiarities in their development.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000312", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.417", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0013455 [Term] id: UBERON:0001757 name: pinna def: "Visible part of the ear that resides outside of the head. The purpose of the pinna is to collect sound. It does so by acting as a funnel, amplifying the sound and directing it to the ear canal. While reflecting from the pinna, sound also goes through a filtering process which adds directional information to the sound (see sound localization, head-related transfer function, pinna notch). The filtering effect of the human pinna preferentially selects sounds in the frequency range of human speech. In various species, the pinna can also signal mood and radiate heat." [Wikipedia:Pinna_(anatomy)] subset: uberon_slim synonym: "auricle" EXACT [] synonym: "auricula" EXACT [Wikipedia:Auricula] synonym: "auricle of ear" EXACT [] synonym: "auricle of external ear" EXACT [] synonym: "auricula (auris externa)" EXACT [] synonym: "pinna of ear" EXACT [] synonym: "pinnae" RELATED PLURAL [] xref: FMA:56580 ! Pinna xref: galen:Auricle xref: VHOG:0000460 ! pinna xref: MA:0000259 ! auricle xref: ncithesaurus:Auricle ! Auricle xref: OpenCyc:Mx4rvs_VC5wpEbGdrcN5Y29ycA ! pinna xref: EHDAA2:0001467 ! pinna xref: EMAPA:17589 ! pinna xref: EV:0100355 ! auricle is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001691 ! external ear relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: SCTID:421159007 ! Entire pinna property_value: external_definition "The external expanded part of the ear characterized by a funnel-shaped structure through which the sound vibrations are received. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000460", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Mammals have a third type of tympanic ear. An external flap, the auricle or pinna, helps funnel sound waves down the external acoustic meatus to the tympanic membrane.[well established][VHOG]" xsd:string {external_class="VHOG:0000460", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.420", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0928075 [Term] id: UBERON:0006938 name: pinna surface epithelium xref: EHDAA2:0001470 ! pinna surface epithelium xref: EMAPA:17592 ! surface epithelium xref: VHOG:0000632 ! pinna surface epithelium xref: EHDAA:8983 ! surface epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001757 ! pinna def: "An epithelium that is part of a pinna." [OBOL:automatic] [Term] id: UBERON:0001758 name: periodontium def: "The tissues that invest or help to invest and support the teeth, including the periodontal ligament, gingivae, cementum, and alveolar and supporting bone[BTO]." [Wikipedia:Periodontium, BTO:0001021] comment: note FMA treats periodontium and periodontal ligament as the same synonym: "paradentium" RELATED [MESH:A14.254.646] synonym: "tooth supporting structure" RELATED [MESH:A14.254.646] synonym: "periodontal membrane" RELATED [MA:0002467] synonym: "periodontal ligament" RELATED INCONSISTENT [FMA:56665] xref: BTO:0001021 ! periodontium xref: FMA:56665 ! Periodontium xref: GAID:216 ! periodontium xref: ncithesaurus:Periodontium ! Periodontium xref: MESH:A14.254.646 ! periodontium is_a: UBERON:0000479 {source="cjm"} ! tissue relationship: adjacent_to UBERON:0001091 ! calcareous tooth relationship: part_of UBERON:0003672 {source="cjm"} ! dentition relationship: has_part CL:0002166 {source="FMA"} ! epithelial cell of malassez xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/The_Periodontium.jpg xref: UMLS:C0031093 [Term] id: UBERON:0008266 name: periodontal ligament def: "The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket[BTO]." [BTO:0001020, Wikipedia:Periodontal_fiber, http://purl.obolibrary.org/obo/uberon/tracker/21] comment: AO notes: FMA treats periodontium and periodontal ligament as the same; it has a separate class desmodentium, which we place here even though it is classified as fetal in FMA synonym: "fibra periodontalis" EXACT LATIN [Wikipedia:Periodontal_ligament] synonym: "periodontal fiber" EXACT LATIN [Wikipedia:Periodontal_ligament] synonym: "periodontal fibre" EXACT LATIN [Wikipedia:Periodontal_ligament] synonym: "PDL" RELATED [Wikipedia:Periodontal_ligament] synonym: "alveolar periosteum" RELATED [BTO:0001020] synonym: "alveolodental ligament" RELATED [BTO:0001020] synonym: "alveolodental membrane" RELATED [BTO:0001020] synonym: "desmodontium" RELATED [BTO:0001020, http://www.drugs.com/dict/desmodentium.html] synonym: "odontoperiosteum" RELATED [BTO:0001020] synonym: "paradentium" RELATED [BTO:0001020] synonym: "peridental membrane" RELATED [BTO:0001020] synonym: "peridontal membrane" RELATED [BTO:0001020] synonym: "peridontal ligament" RELATED [] synonym: "peridontium" RELATED [BTO:0001020] synonym: "peridontal ligament fiber" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal ligament fibre" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal fiber" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal fibre" RELATED [http://www.drugs.com/dict/desmodentium.html] xref: BTO:0001020 ! periodontal ligament xref: GAID:1259 ! periodontal ligament xref: MA:0002467 ! periodontal ligament is_a: UBERON:0008846 {source="FMA-moved"} ! skeletal ligament intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001758 ! periodontium relationship: part_of UBERON:0001758 {source="BTO"} ! periodontium relationship: develops_from UBERON:0002342 {source="UBERONREF:0000002", is_entailed="true"} ! neural crest relationship: develops_from UBERON:0008969 {source="Wikipedia:Dental_follicle", source="PMID:19767574"} ! dental follicle xref: SCTID:245775004 ! Periodontal ligament xref: FMA:76870 ! desmodentium xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/The_Periodontium.jpg property_value: external_definition "The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket[BTO]. It consist of cells, extracellular compartment of fibers. The cells are fibroblast, epithelial, undifferentiated mesenchymal cells, bone and cementum cells. The extracellular compartment consists of collagen fibers bundles embedded in ground substance. The PDL substance has been estimated to be 70% water and is thought to have a significant effect on the tooth's ability to withstand stress loads[WP][BTO:0001020, Wikipedia:Periodontal_fiber, http://purl.obolibrary.org/obo/uberon/tracker/21]." xsd:string {source="Wikipedia:Periodontal_fiber"} property_value: external_definition "The collagen fibers, running from the cementum to the alveolar bone, that suspend a tooth in its socket; they include apical, oblique, horizontal, and alveolar crest fibers, indicating that the orientation of the fibers varies at different levels[http://www.drugs.com/dict/desmodentium.html]." xsd:string {source="http://www.drugs.com/dict/desmodentium.html"} [Term] id: UBERON:0012376 name: retromolar triangle def: "The small area behind the wisdom teeth" [ncithesaurus:Retromolar_Trigone, Wikipedia:Retromolar_space] comment: Editor notes: requires verification synonym: "retromolar trigone" RELATED [] synonym: "retromolar pad" RELATED [] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0001828 ! gingiva xref: FMA:75784 ! retromolar triangle xref: ncithesaurus:Retromolar_Trigone ! retromolar trigone xref: SCTID:245830008 ! Mucosa of retromolar pads of mandibular gingiva xref: UMLS:C0226920 xref: CALOHA:TS-2353 ! Retromolar trigone [Term] id: UBERON:0001759 ! vagus nerve name: vagus nerve def: "Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart)." [ISBN:0471209627, Wikipedia:Vagus_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "CN-X" RELATED [] synonym: "cranial nerve X" RELATED [] synonym: "tenth cranial nerve" EXACT [] synonym: "vagal nerve" RELATED [] synonym: "vagus" EXACT [] synonym: "Vagus nerve [X]" EXACT [] synonym: "vagus nerve tree" EXACT [] synonym: "nervus vagus" RELATED [BTO:0003472] synonym: "pneuomgastric nerve" RELATED [BTO:0003472] synonym: "vagus X nerve" EXACT [MA:0001106] xref: FMA:5731 ! Vagus nerve xref: GAID:721 ! vagus nerve xref: VHOG:0000737 ! vagus nerve xref: MA:0001106 ! vagus X nerve xref: NIF_GrossAnatomy:birnlex_801 ! Vagus nerve xref: TAO:0000453 ! cranial nerve X xref: XAO:0003097 ! cranial nerve X xref: ZFA:0000453 ! cranial nerve X xref: ncithesaurus:Vagus_Nerve ! Vagus Nerve xref: BTO:0003472 ! vagus nerve xref: EFO:0002549 ! vagus nerve xref: galen:VagusNerve ! vagus nerve xref: OpenCyc:Mx4rviHk2ZwpEbGdrcN5Y29ycA ! vagus nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5e/Gray791.png/200px-Gray791.png xref: MESH:A08.800.050.050.925 ! vagus nerve is_a: UBERON:0001785 ! cranial nerve relationship: part_of UBERON:0001033 ! gustatory system relationship: develops_from_part_of UBERON:0005073 {source="GO"} ! preganglionic parasympathetic nervous system relationship: has_developmental_contribution_from UBERON:0005239 {source="Wikipedia", notes="motor"} ! basal plate metencephalon relationship: has_developmental_contribution_from UBERON:0002342 {source="Wikipedia", notes="sensory"} ! neural crest synonym: "nervus vagus [x]" EXACT LATIN [FMA:TA, FMA:5731] xref: AAO:0010475 ! 10 vagus nerve xref: SCTID:362466001 ! Entire vagus nerve synonym: "nervus vagus" RELATED LATIN [Wikipedia:Vagus_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png property_value: external_definition "Nerve consisting of branchiomotor and visceral efferent fibers which branch and innervate the smooth muscles and glands of the heart, lungs, esophagus, and stomach as well as some throat muscles. Sensory fibers supply mucosa of the mouth and pharynx.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010475", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000737", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43\, ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.625", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0042276 [Term] id: UBERON:0005362 name: vagus X ganglion def: "a small, elongated ganglion located between the esophagus and aorta, marking the terminus of the recurrent nerve[WP]" [Wikipedia:Vagus_ganglion] synonym: "gX" BROAD [ZFA:0007067] synonym: "ganglion of vagus nerve" EXACT [FMA:53472] synonym: "right glossopharyngeal ganglion" EXACT [FMA:53472] synonym: "vagus neural ganglion" EXACT [FMA:53472] synonym: "vagus X" RELATED [EMAPA:16798] synonym: "vagal ganglion" EXACT [ZFA:0007067] synonym: "vagus ganglion" EXACT [] xref: MA:0001081 ! vagus X ganglion xref: FMA:53472 ! ganglion of vagus nerve xref: VHOG:0000684 ! vagus X ganglion xref: EMAPA:16798 ! vagus X is_a: UBERON:0009127 {source="ZFA"} ! epibranchial ganglion relationship: overlaps UBERON:0001759 ! vagus nerve xref: SCTID:244452001 ! Vagus nerve ganglion xref: TAO:0007067 ! vagal ganglion xref: ZFA:0007067 ! vagal ganglion [Term] id: UBERON:0005363 name: inferior vagus X ganglion synonym: "inferior ganglion of vagus nerve" EXACT [FMA:6230] synonym: "ganglion inferius (nervus vagus)" EXACT [FMA:6230] synonym: "inferior ganglion of vagus" EXACT [FMA:6230] synonym: "nodose ganglion" EXACT [FMA:6230] synonym: "tenth cranial nerve nodose ganglion" EXACT [FMA:6230] synonym: "vagus nerve inferior ganglion" EXACT [FMA:6230] synonym: "vagus nerve nodose ganglion" EXACT [FMA:6230] synonym: "inferior vagus X" BROAD [EMAPA:17155] synonym: "nodose ganglion" RELATED [EMAPA:17155] xref: MA:0001082 ! inferior vagus X ganglion xref: FMA:6230 ! Inferior ganglion of vagus nerve xref: MESH:A08.340.390.550 ! nodose ganglion xref: VHOG:0000685 ! vagus X inferior ganglion xref: EFO:0002516 ! inferior ganglion of vagus nerve xref: EMAPA:17155 ! inferior of vagus X is_a: UBERON:0005362 ! vagus X ganglion relationship: develops_from UBERON:0009126 {source="EHDAA2"} ! nodosal placode relationship: develops_from UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest synonym: "ganglion inferius nervus vagi" EXACT LATIN [FMA:TA, FMA:6230] xref: SCTID:14420006 ! Vagus nerve nodose ganglion xref: EHDAA2:0004622 ! nodose ganglion synonym: "vagus X inferior ganglion" RELATED [VHOG:0000685] property_value: homology_notes "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000685", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005364 name: superior vagus X ganglion synonym: "superior ganglion of vagus nerve" EXACT [FMA:6229] synonym: "ganglion superius (nervus vagus)" EXACT [FMA:6229] synonym: "jugular ganglion" RELATED [FMA:6229] synonym: "superior ganglion of vagus" EXACT [FMA:6229] synonym: "tenth cranial nerve jugular ganglion" EXACT [FMA:6229] synonym: "vagus nerve jugular ganglion" EXACT [FMA:6229] synonym: "vagus nerve superior ganglion" EXACT [FMA:6229] synonym: "superior vagus X" BROAD [EMAPA:17156] synonym: "gasserian ganglion" RELATED [EMAPA:17156] xref: MA:0001083 ! superior vagus X ganglion xref: FMA:6229 ! Superior ganglion of vagus nerve xref: VHOG:0000686 ! vagus X superior ganglion xref: EMAPA:17156 ! superior of vagus X is_a: UBERON:0005362 ! vagus X ganglion synonym: "ganglion superius nervus vagi" EXACT LATIN [FMA:TA, FMA:6229] xref: SCTID:280197008 ! Superior vagus ganglion synonym: "vagus X superior ganglion" RELATED [VHOG:0000686] [Term] id: UBERON:0011213 name: root of vagus nerve comment: FMA distinguishes between roots and rootlets - we mix the two here synonym: "rX" BROAD [ZFA:0007011] synonym: "vagus root" EXACT [ZFA:0007011] synonym: "vagus neural rootlet" RELATED [FMA:6213] synonym: "vagus nerve root" EXACT [NIF_GrossAnatomy:birnlex_1456] synonym: "rootlet of vagus nerve" EXACT [FMA:6213] synonym: "vagal root" EXACT [ZFA:0007011] intersection_of: UBERON:0006843 ! root of cranial nerve intersection_of: part_of UBERON:0001759 ! vagus nerve xref: FMA:6213 ! rootlet of vagus nerve xref: ZFA:0007011 ! vagal root xref: NIF_GrossAnatomy:birnlex_1456 ! Vagus nerve root def: "A root of cranial nerve that is part of a vagus nerve." [OBOL:automatic] [Term] id: UBERON:0001760 name: frontal sinus def: "The frontal sinus occupies the dorsal part of the skull medial to the orbit. It overlaps cranial and nasal cavities and is often referred to as the conchofrontal sinus. ." [MURDOCH:753, Wikipedia:Frontal_sinus] comment: Taxon notes: A unique feature in the horse is that the frontal sinus communicates with the caudal maxillary sinus via the frontomaxillary opening[MURDOCh] subset: uberon_slim synonym: "cavity of frontal bone" EXACT [FMA:57417] xref: FMA:57417 ! Frontal sinus xref: GAID:357 ! frontal sinus xref: MA:0001793 ! frontal sinus xref: ncithesaurus:Frontal_Sinus xref: OpenCyc:Mx4rvqMUR5wpEbGdrcN5Y29ycA ! frontal sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Nnh_front.svg/200px-Nnh_front.svg.png xref: MESH:A04.531.621.387 ! frontal sinus is_a: UBERON:0001825 {source="MA"} ! paranasal sinus xref: SCTID:181205008 ! Entire frontal sinus synonym: "sinus frontales" RELATED LATIN [Wikipedia:Frontal_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/f/fb/Nnh_front.svg xref: UMLS:C0016734 [Term] id: UBERON:0001761 name: foramen caecum of thyroid subset: uberon_slim synonym: "foramen caecum" BROAD [MA:0000725] xref: EHDAA:2150 ! foramen caecum xref: EHDAA:2977 ! foramen caecum xref: VHOG:0000826 ! foramen caecum xref: MA:0000725 ! foramen caecum xref: EHDAA2:0000550 ! foramen caecum xref: EMAPA:17069 ! foramen caecum of thyroid of gland of foregut xref: EMAPA:18828 ! foramen caecum of thyroid of gland of gut is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002046 ! thyroid gland property_value: external_definition "A thickened and indented region in the midline in the floor of the rostral part of the pharyngeal region of the foregut, located between the second and third branchial arches that is the first indication of the thyroid primordium. [Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.132][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000826", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006699 name: foramen caecum of tongue def: "The dorsum of the tongue is convex and marked by a median sulcus, which divides it into symmetrical halves; this sulcus ends behind, about 2.5 cm from the root of the organ, in a depression, the foramen cecum, from which a shallow groove, the sulcus terminalis, runs lateral and anterior on either side to the margin of the tongue. The foramen cecum is the point of attachment of the thyroglossal duct and is formed during the embryological descent of the thyroid gland." [Wikipedia:Foramen_cecum_%28tongue%29] comment: consider merging with FC of thyroid synonym: "foramen cecum of tongue" EXACT [FMA:54828] synonym: "foramen of morgagni" EXACT [FMA:54828] synonym: "morand's foramen" EXACT [FMA:54828] xref: FMA:54828 ! foramen caecum of tongue is_a: UBERON:0000061 ! anatomical structure relationship: develops_from UBERON:0002539 ! pharyngeal arch disjoint_from: UBERON:0006713 ! foramen cecum of frontal bone xref: SCTID:368738001 ! Entire foramen cecum of tongue synonym: "f. caecum linguae" RELATED LATIN [Wikipedia:Foramen_cecum_%28tongue%29] xref: http://upload.wikimedia.org/wikipedia/commons/a/a3/Foramen_caecum.png [Term] id: UBERON:0006713 ! foramen cecum of frontal bone name: foramen cecum of frontal bone def: "The frontal crest of the frontal bone ends below in a small notch which is converted into a foramen, the foramen cecum, by articulation with the ethmoid. This foramen varies in size in different subjects, and is frequently impervious; when open, it transmits a vein from the nose to the superior sagittal sinus. This has clinical importance in that infections of the nose and nearby areas can be transmitted to the meninges and brain from what is known as the danger triangle of the face." [Wikipedia:Foramen_cecum_%28frontal_bone%29] comment: todo - check if this is what the FMA ID really denotes xref: FMA:57443 ! Foramen caecum is_a: UBERON:0005744 ! cranial conduit synonym: "f. caecum ossis frontalis" RELATED LATIN [Wikipedia:Foramen_cecum_%28frontal_bone%29] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Gray135.png [Term] id: UBERON:0000130 name: transverse foramen def: "Foramen that pierces the transverse processes of the seven cervical vertebrae. In the upper six vertebrae, the foramen gives passage to the vertebral artery, vertebral vein, and a plexus of sympathetic nerves. The seventh foramen lacks the artery, but contains the vein and sympathetic nerves." [Wikipedia:Transverse_foramen] is_a: UBERON:0004111 {source="FMA"} ! anatomical conduit relationship: part_of UBERON:0001077 ! transverse process of vertebra relationship: part_of UBERON:0002413 ! cervical vertebra synonym: "foramen transversarium of cervical vertebra" EXACT [FMA:23998] synonym: "transverse foramen of cervical vertebra" EXACT [FMA:23997] synonym: "foramen transversarium" EXACT [Wikipedia:Transverse_foramen] xref: FMA:23997 ! transverse foramen of cervical vertebra xref: SCTID:280735005 ! Foramen transversarium synonym: "foramen transversarium" RELATED LATIN [Wikipedia:Transverse_foramen] xref: http://upload.wikimedia.org/wikipedia/commons/3/3c/Gray84.png [Term] id: UBERON:0008426 name: transverse foramen of atlas synonym: "foramen transversarium of atlas" EXACT [FMA:23998] intersection_of: UBERON:0000130 ! transverse foramen intersection_of: part_of UBERON:0001092 ! atlas xref: FMA:23998 ! transverse foramen of atlas xref: SCTID:281220001 ! Entire transverse foramen of atlas def: "A transverse foramen that is part of a cervical vertebra 1." [OBOL:automatic] [Term] id: UBERON:0008427 name: transverse foramen of axis synonym: "foramen transversarium of axis" EXACT [FMA:23999] intersection_of: UBERON:0000130 ! transverse foramen intersection_of: part_of UBERON:0001093 ! cervical vertebra 2 xref: FMA:23999 ! transverse foramen of axis xref: SCTID:281221002 ! Foramen transversarium of axis relationship: in_lateral_side_of UBERON:0001093 {source="FMA-abduced-lr"} ! cervical vertebra 2 def: "A transverse foramen that is part of a cervical vertebra 2." [OBOL:automatic] [Term] id: UBERON:0005913 ! zone of bone organ name: zone of bone organ synonym: "bone organ zone" EXACT [FMA:10483] xref: FMA:10483 ! zone of bone organ is_a: UBERON:0000064 ! organ part is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0001474 ! bone element [Term] id: UBERON:0006203 name: conchal part of pinna synonym: "concha" BROAD [FMA:61006] synonym: "concha of auricle" EXACT [FMA:61006] synonym: "concha of pinna" EXACT [FMA:61006] xref: FMA:61006 ! conchal part of pinna is_a: UBERON:0000064 ! organ part disjoint_from: UBERON:0001762 ! nasal concha relationship: part_of UBERON:0001757 ! pinna synonym: "concha auriculae" EXACT LATIN [FMA:TA, FMA:61006] xref: ncithesaurus:Concha ! Concha xref: UMLS:C0229316 [Term] id: UBERON:0001762 ! nasal concha name: nasal concha def: "In anatomy, a nasal concha (or turbinate) is a long, narrow and curled bone shelf (shaped like an elongated sea-shell) which protrudes into the breathing passage of the nose. Turbinate bone refers to any of the scrolled spongy bones of the nasal passages in vertebrates. In humans, the turbinates divide the nasal airway into three groove-like air passages –and are responsible for forcing inhaled air to flow in a steady, regular pattern around the largest possible surface of cilia and climate controlling tissue. [WP,unvetted]." [Wikipedia:Nasal_concha] comment: Note that FMA considers nasal concha and nasal concha of ethmoid bone to be synonymous. We disambiguate these here // Turbinals are only ossified in birds and derived synapsids. subset: uberon_slim synonym: "concha" RELATED [EMAPA:25093] synonym: "turbinate bone" EXACT [EMAPA:25093] synonym: "nasal turbinate" EXACT [] synonym: "turbinate" EXACT [] synonym: "turbinal" EXACT [palaeos.com/vertebrates/bones/braincase/ethmoid.html] xref: GAID:224 ! turbinate xref: MA:0000286 ! nasal turbinate xref: EMAPA:25093 ! turbinate bone xref: OpenCyc:Mx4rv07bVJwpEbGdrcN5Y29ycA xref: ncithesaurus:Nasal_Turbinate ! Nasal Turbinate xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Gray153.png/200px-Gray153.png xref: MESH:A02.835.232.781.324.948 ! turbinate is_a: UBERON:0005913 ! zone of bone organ relationship: located_in UBERON:0001707 ! nasal cavity relationship: part_of UBERON:0011241 {source="Kardong"} ! ethmoid region xref: EHDAA2:0004101 ! nasal conchae xref: SCTID:361931007 ! Entire nasal turbinate synonym: "conchae nasales" RELATED LATIN [Wikipedia:Nasal_concha] xref: http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray153.png xref: UMLS:C1266928 [Term] id: UBERON:0003973 ! nasal concha of ethmoid bone name: nasal concha of ethmoid bone def: "One of the conchae of the ethmoid bone, which occupy the caudal part of the nasal fossae and form the lateral and superior portions of the turbinate bones in mammals[MP]. The ethmoturbinals are associated with the cribiform plate. They are covered with olfactory epithelium. Primarily, they serve to increase the surface area over which olfactory receptor neurons can come in contact with respiratory air. These olfactory receptor nerves then synapse with the mitral cells of the olfactory lobes through the cribiform plate in the manner described above[Palaeos]" [MP:0008971, palaeos.com/vertebrates/bones/braincase/ethmoid.html] comment: Note that FMA considers nasal concha and nasal concha of ethmoid bone to be synonymous. We disambiguate these here synonym: "ethmo-turbinate" EXACT [] synonym: "ethmoturbinal" EXACT [http://palaeos.com/vertebrates/bones/braincase/ethmoid.html] synonym: "ethmoturbinate" EXACT [MP:0008971] synonym: "nasal turbinate of ethmoid bone" EXACT [] synonym: "turbinate of ethmoid bone" EXACT [] xref: FMA:57456 ! Nasal concha intersection_of: UBERON:0001762 ! nasal concha intersection_of: part_of UBERON:0001679 ! ethmoid relationship: develops_from UBERON:0006332 {source="ISBN10:0073040584"} ! nasal capsule relationship: only_in_taxon NCBITaxon:32523 {source="MP:0008971"} ! Tetrapoda [Term] id: UBERON:0010889 name: ectethmoid def: "either of two lateral parts of the ethmoid bone that form part of the anterior wall of the orbit " [http://www.merriam-webster.com/medical/ectethmoid] synonym: "dorsal nasal capsule" EXACT [PMID:21270050] comment: Taxon notes: In avians, the mesethmoid supports upper beak formation is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001679 ! ethmoid [Term] id: UBERON:0005919 name: supreme nasal concha def: "a thin bony plate occasionally found projecting from the inner wall of the ethmoid labyrinth, above the bony superior nasal concha, and the mucous membrane covering the plate." [http://medical-dictionary.thefreedictionary.com/supreme+nasal+concha] synonym: "highest nasal concha" EXACT [FMA:57457] synonym: "supreme nasal turbinate" EXACT [FMA:57457] synonym: "supreme turbinate" EXACT [FMA:57457] xref: FMA:57457 ! supreme nasal concha is_a: UBERON:0003973 ! nasal concha of ethmoid bone synonym: "concha nasi suprema" EXACT LATIN [FMA:TA, FMA:57457] xref: SCTID:361935003 ! Entire supreme nasal turbinate [Term] id: UBERON:0005920 name: superior nasal concha def: "The back part of the medial surface of the labyrinth of ethmoid is subdivided by a narrow oblique fissure, the superior meatus of the nose, bounded above by a thin, curved plate, the superior nasal concha. The bone found in superior nasal concha is part of the ethmoid bone." [Wikipedia:Superior_nasal_concha] synonym: "superior concha" RELATED [Wikipedia:Superior_nasal_concha] synonym: "superior nasal turbinate" EXACT [FMA:57458] synonym: "superior turbinate" EXACT [FMA:57458] xref: FMA:57458 ! superior nasal concha is_a: UBERON:0003973 ! nasal concha of ethmoid bone xref: SCTID:361934004 ! Entire superior nasal turbinate xref: http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray151.png [Term] id: UBERON:0005921 name: middle nasal concha def: "The medial surface of the labyrinth of ethmoid consists of a thin lamella, which descends from the under surface of the cribriform plate, and ends below in a free, convoluted margin, the middle nasal concha. It is rough, and marked above by numerous grooves, directed nearly vertically downward from the cribriform plate; they lodge branches of the olfactory nerves, which are distributed to the mucous membrane covering the superior nasal concha." [Wikipedia:Middle_nasal_concha] synonym: "middle concha" RELATED [Wikipedia:Middle_nasal_concha] synonym: "middle nasal turbinate" EXACT [FMA:57459] synonym: "middle turbinate" EXACT [FMA:57459] xref: FMA:57459 ! middle nasal concha is_a: UBERON:0003973 ! nasal concha of ethmoid bone xref: SCTID:361933005 ! Entire middle nasal turbinate xref: http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray151.png [Term] id: UBERON:0005922 ! inferior nasal concha name: inferior nasal concha def: "The inferior nasal concha (Inferior Turbinated Bone) is one of the turbinates in the nose. It extends horizontally along the lateral wall of the nasal cavity [Fig. 1] and consists of a of spongy bone, curled upon itself like a scroll. Each inferior nasal concha is considered a facial pair of bones since they arise from the maxillae bones and projects horizontally into the nasal cavity. They are also termed 'inferior nasal turbinates' because they function similar to that of a turbine. As the air passes through the turbinates, the air is churned against these mucosa-lined bones in order to receive warmth, moisture and cleansing. Superior to inferior nasal concha are the middle nasal concha and superior nasal concha which arise from the cranial portion of the skull. Hence, these two are considered as a part of the cranial bones. It has two surfaces, two borders, and two extremities." [Wikipedia:Inferior_nasal_concha] comment: note that in FMA this is not classified with the other turbinates. In Uberon we subdivide the turbinates into the ethmoturbinates and the inferior turbinate. TODO: check ethmoidal process of inferior nasal concha synonym: "inferior concha" RELATED [Wikipedia:Inferior_nasal_concha] synonym: "inferior turbinated" RELATED [Wikipedia:Inferior_nasal_concha] synonym: "inferior nasal turbinate" EXACT [FMA:54736] synonym: "inferior nasal turbinate bone" EXACT [] synonym: "inferior turbinate" EXACT [FMA:54736] xref: FMA:54736 ! inferior nasal concha is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0001762 ! nasal concha relationship: part_of UBERON:0011156 ! facial skeleton relationship: develops_from UBERON:0006332 {source="ISBN10:1588903958"} ! nasal capsule relationship: connected_to UBERON:0001682 {source="dbpedia"} ! palatine bone relationship: connected_to UBERON:0002397 {source="dbpedia"} ! maxilla xref: ncithesaurus:Inferior_Turbinate ! Inferior Turbinate xref: SCTID:361932000 ! Entire inferior nasal turbinate xref: SCTID:362882006 ! Entire inferior nasal turbinate bone synonym: "concha nasi inferior, concha nasalis inferior" RELATED LATIN [Wikipedia:Inferior_nasal_concha] xref: http://upload.wikimedia.org/wikipedia/commons/6/62/Gray192.png relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: UMLS:C0225434 [Term] id: UBERON:0005869 ! maxillary process of inferior nasal concha name: maxillary process of inferior nasal concha def: "From the lower border of the inferior nasal concha, a thin lamina, the maxillary process, curves downward and lateralward; it articulates with the maxilla and forms a part of the medial wall of the maxillary sinus." [Wikipedia:Maxillary_process_of_inferior_nasal_concha] synonym: "maxilloturbinal" RELATED [palaeos.com/vertebrates/bones/braincase/ethmoid.html] synonym: "maxillary process of inferior concha" EXACT [FMA:54741] synonym: "maxillary process of inferior nasal turbinate" EXACT [FMA:54741] synonym: "maxillary process of inferior turbinate" EXACT [FMA:54741] synonym: "processus maxillaris (concha nasalis inferior)" EXACT [FMA:54741] xref: FMA:54741 ! maxillary process of inferior nasal concha is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0005922 ! inferior nasal concha synonym: "processus maxillaris conchae nasalis inferioris" EXACT LATIN [FMA:TA, FMA:54741] synonym: "p. maxillaris conchae nasalis inferioris" RELATED LATIN [Wikipedia:Maxillary_process_of_inferior_nasal_concha] xref: http://upload.wikimedia.org/wikipedia/commons/7/7c/Gray172.png [Term] id: UBERON:0005925 name: ethmoidal process of inferior nasal concha def: "Behind the lacrimal process of the inferior nasal conchae lies a broad, thin plate, the ethmoidal process, which ascends to join the uncinate process of the ethmoid; from its lower border a thin lamina, the maxillary process, curves downward and lateralward; it articulates with the maxilla and forms a part of the medial wall of the maxillary sinus." [Wikipedia:Ethmoid_boneal_process_of_inferior_nasal_concha] synonym: "ethmoidal process of inferior concha" EXACT [FMA:54742] synonym: "ethmoidal process of inferior nasal turbinate" EXACT [FMA:54742] synonym: "ethmoidal process of inferior turbinate" EXACT [FMA:54742] synonym: "processus ethmoidalis (concha nasalis inferior)" EXACT [FMA:54742] xref: FMA:54742 ! ethmoidal process of inferior nasal concha is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0005922 ! inferior nasal concha synonym: "processus ethmoidalis conchae nasalis inferioris" EXACT LATIN [FMA:TA, FMA:54742] synonym: "processus ethmoidalis conchae nasalis inferioris" RELATED LATIN [Wikipedia:Ethmoidal_process_of_inferior_nasal_concha] [Term] id: UBERON:0001764 name: maxillary sinus def: "One of the paired paranasal sinuses, located in the body of the maxilla, communicating with the middle meatus of the nasal cavity." [MESH:A04.531.621.578, Wikipedia:Maxillary_sinus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "antrum of Highmore" EXACT [] synonym: "highmore antrum" RELATED [MESH:A04.531.621.578] synonym: "maxillary antrum" RELATED [MESH:A04.531.621.578] xref: FMA:57715 ! Maxillary sinus xref: GAID:358 ! maxillary sinus xref: MA:0001794 ! maxillary sinus xref: ncithesaurus:Maxillary_Sinus xref: OpenCyc:Mx4rvp2ZWJwpEbGdrcN5Y29ycA ! maxillary sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3d/Gray1199.png/200px-Gray1199.png xref: MESH:A04.531.621.578 ! maxillary sinus is_a: UBERON:0001825 ! paranasal sinus relationship: in_lateral_side_of UBERON:0000033 ! head xref: SCTID:181204007 ! Entire maxillary sinus synonym: "sinus maxilliaris" RELATED LATIN [Wikipedia:Maxillary_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Gray1199.png xref: UMLS:C0024957 [Term] id: UBERON:0006311 ! chamber of eyeball name: chamber of eyeball def: "Chamber of eyeball[FMA]" [FMA:58071] synonym: "eyeball chamber" EXACT [FMA:58071] synonym: "eye chamber" EXACT [MA:0002459] xref: FMA:58071 ! chamber of eyeball xref: MA:0002459 ! eye chamber xref: BTO:0002085 ! chamber of the eye is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000019 ! camera-type eye xref: ncithesaurus:Chamber_of_the_Eye ! Chamber of the Eye xref: SCTID:280540004 ! Chamber of eye xref: UMLS:C0459556 [Term] id: UBERON:0001766 name: anterior chamber of eyeball def: "the fluid-filled space inside the eye between the iris and the cornea's innermost surface, the endothelium.[1] Aqueous humor is the fluid that fills the anterior chamber. Hyphema and glaucoma are two main pathologies in this area. In hyphema, blood fills the anterior chamber. In glaucoma, blockage of the canal of Schlemm prevents the normal outflow of aqueous humor, resulting in accumulation of fluid, increased intraocular pressure, and eventually blindness." [Wikipedia:Anterior_chamber_of_eyeball] comment: AO notes: space in EHDAA2 - consider adding Cavity of anterior chamber of eyeball synonym: "anterior chamber" EXACT [HP:0000593, MP:0010709] synonym: "anterior chamber of eye" EXACT [] synonym: "camera anterior" EXACT [] synonym: "eye anterior chamber" EXACT [] xref: FMA:58078 ! Anterior chamber of eyeball xref: VHOG:0001431 ! eye anterior chamber xref: MA:0000262 ! eye anterior chamber xref: GAID:889 ! anterior chamber xref: EHDAA:9033 ! anterior chamber xref: EHDAA2:0000129 ! anterior chamber xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: BTO:0002084 ! anterior chamber of the eye xref: EMAPA:18231 ! anterior chamber xref: MESH:A09.371.060.067 ! anterior chamber is_a: UBERON:0006311 {source="FMA"} ! chamber of eyeball relationship: part_of UBERON:0001801 ! anterior segment of eyeball xref: ncithesaurus:Anterior_Chamber_of_the_Eye ! Anterior Chamber of the Eye xref: SCTID:181160009 ! Entire anterior chamber of eye synonym: "camera anterior bulbi oculi" RELATED LATIN [Wikipedia:Anterior_chamber_of_eyeball] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg property_value: external_definition "The part of the eyeball between the cornea and the iris, filled with aqueous humor. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001431", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/anterior+chamber", source="http://bgee.unil.ch/"} xref: UMLS:C0003151 [Term] id: UBERON:0001767 name: posterior chamber of eyeball def: "a narrow chink behind the peripheral part of the iris of the lens, and in front of the suspensory ligament of the lens and the ciliary processes the Posterior Chamber consists of small space directly posterior of the Iris but anterior to the lens." [Wikipedia:Posterior_chamber_of_eyeball] comment: The posterior chamber should not be confused with vitreous chamber. synonym: "camera posterior" EXACT [] synonym: "eye posterior chamber" EXACT [] synonym: "posterior chamber of eye" EXACT [] xref: FMA:58080 ! Posterior chamber of eyeball xref: MA:0002460 ! eye posterior chamber xref: OpenCyc:Mx4rvnYe8pwpEbGdrcN5Y29ycA ! posterior chamber of eye xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray883.png/200px-Gray883.png xref: BTO:0002086 ! posterior chamber of the eye is_a: UBERON:0006311 ! chamber of eyeball relationship: part_of UBERON:0001801 ! anterior segment of eyeball xref: ncithesaurus:Posterior_Chamber_of_the_Eye ! Posterior Chamber of the Eye xref: SCTID:362504004 ! Entire posterior chamber of eye synonym: "c. posterior bulbi" RELATED LATIN [Wikipedia:Posterior_chamber_of_eyeball] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png xref: UMLS:C0229094 [Term] id: UBERON:0001768 name: uvea def: "pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]." [Wikipedia:Uvea] comment: TODO - check child terms, isa vs partof. See also MA:0001284 ! tunica vasculosa plexus subset: uberon_slim synonym: "tunica vasculosa of eyeball" EXACT [FMA:58103] synonym: "uvea" EXACT [FMA:58103] synonym: "uveal tract" EXACT [FMA:58103] synonym: "pars iridica retinae" RELATED [Wikipedia:Uvea] synonym: "tunica vasculatis oculi" RELATED [Wikipedia:Uvea] synonym: "tunica vasculosa bulbi" RELATED LATIN [Wikipedia:Uvea] xref: FMA:58103 ! vascular layer of eyeball xref: GAID:912 ! uvea xref: MA:0002480 ! uvea xref: ncithesaurus:Uvea ! Uvea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/eb/Gray869.png/200px-Gray869.png xref: MESH:A09.371.894 ! uvea is_a: UBERON:0002049 ! vasculature relationship: part_of UBERON:0001801 ! anterior segment of eyeball relationship: present_in_taxon NCBITaxon:7955 {source="doi:10.1177/0192623311409597"} ! Danio rerio xref: SCTID:280648000 ! Entire uveal tract xref: http://upload.wikimedia.org/wikipedia/commons/e/eb/Gray869.png synonym: "vascular layer of eyeball" RELATED [FMA:58103] property_value: has_relational_adjective "uveal" xsd:string xref: UMLS:C0042160 [Term] id: UBERON:0011892 ! anterior uvea name: anterior uvea def: "Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris." [MP:0005194] synonym: "Haller tunica vascula" EXACT [MP:0005194] synonym: "tunica vasculosa bulbosa" EXACT [MP:0005194] synonym: "ciliary body and iris" RELATED [] synonym: "ventral uveal tract" EXACT [] synonym: "anterior uveal tract" EXACT [] synonym: "anterior part of uveal tract" EXACT [] synonym: "anterior vascular layer of the eyeball" EXACT [] synonym: "anterior vascular tunic of the eye" EXACT [] synonym: "vasculosa oculi" RELATED [MP:0005194] is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: part_of UBERON:0001768 {source="MP"} ! uvea relationship: part_of UBERON:0001801 ! anterior segment of eyeball relationship: has_part UBERON:0001769 ! iris relationship: has_part UBERON:0001775 ! ciliary body xref: SCTID:280656002 ! Entire anterior part of uveal tract [Term] id: UBERON:0001769 name: iris def: "a membrane in the eye, responsible for controlling the amount of light reaching the retina. The iris consists of pigmented fibrovascular tissue known as a stroma. It is the most forward portion of the eye and the only one seen on superficial inspection. The stroma connects a sphincter muscle (sphincter pupillae), which contracts the pupil, and a set of dilator muscles (dilator pupillae) which open it. The back surface is covered by a heavily pigmented epithelial layer two cells thick (the iris pigment epithelium), but the front surface has no epithelium. The high pigment content blocks light from passing through the iris and restricts it to the pupil. The outer edge of the iris, known as the root, is attached to the sclera and the anterior ciliary body. The iris and ciliary body together are known as the anterior uvea. Just in front of the root of the iris is the region through which the aqueous humour constantly drains out of the eye, with the result that diseases of the iris often have important effects on intraocular pressure, and indirectly on vision. Depending on the amount of light, the iris makes the pupil larger or smaller." [Wikipedia:Iris_(anatomy)] comment: Taxon notes: The avian iris and ciliary body undergoes a transition from smooth-to-striated muscle during embryonic development - dx.doi.org/10.1006/dbio.1998.9019 subset: uberon_slim subset: vertebrate_core synonym: "anterior uvea" RELATED [] xref: BTO:0000653 xref: FMA:58235 ! Iris xref: GAID:917 ! iris xref: VHOG:0000101 ! iris xref: MA:0000273 ! iris xref: OpenCyc:Mx4rvVjbppwpEbGdrcN5Y29ycA xref: TAO:0001238 ! iris xref: XAO:0000185 ! iris xref: ZFA:0001238 ! iris xref: ncithesaurus:Iris ! Iris xref: EMAPA:19154 ! iris xref: MESH:A09.371.894.513 ! iris xref: EV:0100345 ! iris is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0011892 ! anterior uvea relationship: develops_from UBERON:0004128 {source="XAO"} ! optic vesicle xref: AAO:0010347 ! iris xref: SCTID:181164000 ! Entire iris synonym: "irises" RELATED PLURAL [VHOG:0000101] property_value: external_definition "The opaque muscular contractile diaphragm suspended in the aqueous humour in front of the lens of the eye. The organ is perforated by the pupil and continues peripherally with the ciliary body. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000101", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {external_class="VHOG:0000101", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: EFO:0004245 ! iris xref: UMLS:C0022077 [Term] id: UBERON:0004118 name: vasculature of iris def: "A vasculature that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "iris vasculature" EXACT [] synonym: "iris vascular network" EXACT [OBOL:automatic] synonym: "vascular network of iris" EXACT [OBOL:automatic] synonym: "iris blood vessels" EXACT [ZFA:0005568] xref: ZFA:0005568 ! iris blood vessels (also: UBERON:0003511 'iris blood vessel') is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001769 ! iris [Term] id: UBERON:0001775 name: ciliary body def: "circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [Wikipedia:Ciliary_body] subset: uberon_slim subset: vertebrate_core synonym: "ocular ciliary body" EXACT [] synonym: "anterior uvea" RELATED [] synonym: "corpus ciliare" RELATED [Wikipedia:Ciliary_body] xref: BTO:0000260 xref: FMA:58295 ! Ciliary body xref: GAID:916 ! ciliary body xref: VHOG:0000102 ! ciliary body xref: MA:0000264 ! ciliary body xref: ncithesaurus:Ciliary_Body xref: XAO:0000186 ! ciliary body xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: EMAPA:19065 ! ciliary body xref: MESH:A09.371.894.280 ! ciliary body xref: EV:0100346 ! ciliary body is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0011892 ! anterior uvea xref: AAO:0010341 ! ciliary body xref: SCTID:263340007 ! Entire ciliary body synonym: "corpus ciliare" RELATED LATIN [Wikipedia:Ciliary_body] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg synonym: "ciliary bodies" RELATED PLURAL [VHOG:0000102] property_value: homology_notes "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {external_class="VHOG:0000102", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0008779 [Term] id: UBERON:0011221 name: ora serrata of retina def: "The ora serrata is the serrated junction between the retina and the ciliary body. This junction marks the transition from the simple non-photosensitive area of the retina to the complex, multi-layered photosensitive region. In animals in which the region does not have a serrated appearance, it is called the ora ciliaris retinae." [Wikipedia:Ora_serrata] synonym: "ora ciliaris retina" RELATED [Wikipedia:Ora_serrata] synonym: "ora ciliaris retinae" RELATED [Wikipedia:Ora_serrata] synonym: "ora serrata retinae" EXACT LATIN [FMA:TA] synonym: "ora serrata" EXACT [FMA:58600] is_a: UBERON:0007651 ! anatomical junction relationship: connects UBERON:0000966 ! retina relationship: connects UBERON:0001775 ! ciliary body relationship: part_of UBERON:0001766 ! anterior chamber of eyeball xref: FMA:58600 ! ora serrata xref: SCTID:280612002 ! Entire ora serrata of retina [Term] id: UBERON:0004868 name: tapetum lucidum namespace: uberon def: "a layer of tissue in the eye of many vertebrate animals, that lies immediately behind or sometimes within the retina. It reflects visible light back through the retina, increasing the light available to the photoreceptors" [Wikipedia:Tapetum_lucidum, PMID:14738502] comment: Function notes: It normally functions at low light levels to provide the light-sensitive retinal cells with a second opportunity for photon-photoreceptor stimulation, thereby enhancing visual sensitivity synonym: "tapis luisant@fr" EXACT [] synonym: "tapeta lucida" EXACT PLURAL [] is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0010230 ! eyeball of camera-type eye relationship: never_in_taxon NCBITaxon:9443 {source="PMID:14738502", editor="cjm"} ! Primates relationship: never_in_taxon NCBITaxon:8782 {source="PMID:14738502", editor="cjm"} ! Aves relationship: never_in_taxon NCBITaxon:9822 {source="PMID:14738502", editor="cjm"} ! Sus relationship: never_in_taxon NCBITaxon:9321 {source="PMID:14738502", editor="cjm"} ! Macropus rufus xref: http://upload.wikimedia.org/wikipedia/commons/7/76/TapetumLucidum.JPG property_value: external_definition "The tapetum lucidum is a biologic reflector system that is a common feature in the eyes of vertebrates. Typically absent in diurnal animals. In vertebrates, the tapetum lucidum exhibits diverse structure, organization and composition. The tapetum lucidum represents a remarkable example of neural cell and tissue specialization as an adaptation to a dim light environment and, despite these differences, all tapetal variants act to increase retinal sensitivity by reflecting light back through the photoreceptor layer. These variations regarding both its location and structure, as well as the choice of reflective material, may represent selective visual adaptations associated with their feeding behavior, in response to the use of specific wavelengths and amount of reflectance required.[PMID:14738502]." xsd:string {source="PMID:14738502"} property_value: taxon_notes "Two morphologic types of tapetum lucidum can be observed in the eyes of fish: one in the choroid that occurs in elasmobranchs, and the other which occurs in teleosts and lies in the pigment epithelium of the retina" xsd:string {source="PMID:14738502"} property_value: has_relational_adjective "tapetal" xsd:string [Term] id: UBERON:0010244 name: choroid tapetum lucidum def: "A tapetum lucidum that is part of the choroid. The choroidal tapetum lucidum lies immediately adjacent to the choriocapillaris and external to the retinal epithelium" [UBERON:cjm, Wikipedia:Tapetum_lucidum#Classification, PMID:14738502] comment: AO notes: we make the assumption that the BTO class belongs here rather than with the parent; the other type is the retinal type synonym: "tapetum choroideae" EXACT [BTO:0001828] synonym: "choroidal tapetum lucidum" EXACT [] intersection_of: UBERON:0004868 ! tapetum lucidum intersection_of: part_of UBERON:0001776 ! optic choroid relationship: adjacent_to UBERON:0000966 ! retina xref: BTO:0001828 ! tapetum lucidum xref: SCTID:3034006 ! Tapetum lucidum [Term] id: UBERON:0010245 name: retinal tapetum lucidum def: "A tapetum lucidum that is part of the retina, within the cytoplasm of the retinal epithelium" [UBERON:cjm, Wikipedia:Tapetum_lucidum#Classification, PMID:14738502] comment: Taxon notes: as seen in teleosts, crocodiles, marsupials and fruit bats[WP] intersection_of: UBERON:0004868 ! tapetum lucidum intersection_of: part_of UBERON:0000966 ! retina relationship: present_in_taxon NCBITaxon:8493 {source="PMID:14738502", editor="cjm"} ! Crocodylidae relationship: present_in_taxon NCBITaxon:9263 {source="PMID:14738502", editor="cjm"} ! Metatheria relationship: present_in_taxon NCBITaxon:32443 {source="PMID:14738502", editor="cjm"} ! Teleostei relationship: present_in_taxon NCBITaxon:30559 {source="PMID:14738502", editor="cjm"} ! Megachiroptera property_value: taxon_notes "Retinal tapeta lucida are common in fish and some reptiles, but rarely occur in mammals. In most of these species the retinal tapetum can be classified as either a lipid (in some teleosts, mammals) or guanine type (in some teleosts, reptiles). Another differentiation can be made among the retinal tapeta lucida based on whether the tapetum is occlusible (found in most of teleosts), or nonocclusible (or static) (found in mammals)" xsd:string {source="PMID:14738502"} property_value: taxon_notes "the tapetum lucidum is an integral part of the pigment epithelium in primitive teleosts (lying in the pro- cesses of the pigmented epithelial cells). It can vary in chemical nature. " xsd:string {source="PMID:14738502", taxon="NCBITaxon:32443"} property_value: taxon_notes "In crocodilians, a semicircular area of the retinal epithelium in the superior fundus shows a fair sulfur yellow coloration and is specialized as a tapetum lucidum. " xsd:string {source="PMID:14738502", taxon="NCBITaxon:8493"} property_value: taxon_notes "In the tapetal area, no melanosomes are formed indicating a nonocclusible tapetum in the Caiman sclerops. " xsd:string {source="PMID:14738502", taxon="NCBITaxon:8499"} [Term] id: UBERON:0010246 name: choroidal guanine tapetum def: "A choroid tapetum lucidum that is made of a palisade of cells containing stacks of flat hexagonal crystals of guanine" [UBERON:cjm, Wikipedia:Tapetum_lucidum#Classification, PMID:14738502] comment: Taxon notes: elasmobranchii (skates, rays, and sharks) and chimaeras[WP] is_a: UBERON:0010244 ! choroid tapetum lucidum relationship: only_in_taxon NCBITaxon:7778 ! Elasmobranchii relationship: present_in_taxon NCBITaxon:7778 ! Elasmobranchii relationship: present_in_taxon NCBITaxon:7864 ! Chimaeriformes property_value: taxon_notes "The elasmobranch tapetum in Squalus and Scyliorhinus con- sists of sheets of 12–13 superposed guanine crystals in the choroid." xsd:string {source="PMID:14738502", taxon="NCBITaxon:7778"} property_value: taxon_notes "A choroidal tapetum of reflecting cells lying immediately outside the choriocapillaris is formed in a few primitive teleosts." xsd:string {source="PMID:14738502", taxon="NCBITaxon:32443"} [Term] id: UBERON:0010247 name: choroidal tapetum cellulosum def: "A choroid tapetum lucidum that consists of layers of cells containing organized, highly refractive crystals. These crystals are diverse in shape and makeup" [UBERON:cjm, Wikipedia:Tapetum_lucidum#Classification, PMID:14738502] comment: The choroidal stroma adjacent to the tapetum lucidum contains numerous small blood vessels that penetrate the tapetal layer to form a single-layered capillary network, known as the choriocapillaris, on the surface of the tapetum. The tapetum cellulosum is thus interposed between the large branching vessels in the choroid and the single layer of the choriocapillaris beneath the retinal epithelium[PMID:14738502] synonym: "choroid tapetum cellulosum" EXACT [] is_a: UBERON:0010244 ! choroid tapetum lucidum relationship: only_in_taxon NCBITaxon:9347 ! Eutheria relationship: present_in_taxon NCBITaxon:9721 {source="PMID:14738502", editor="cjm"} ! Cetacea relationship: present_in_taxon NCBITaxon:9989 {source="PMID:14738502", editor="cjm", taxon="spotted cavy"} ! Rodentia relationship: present_in_taxon NCBITaxon:33554 {source="PMID:14738502", editor="cjm", notes="most carnivores"} ! Carnivora [Term] id: UBERON:0010248 name: choroidal tapetum fibrosum def: "A choroid tapetum lucidum that is an array of extracellular fibers." [UBERON:cjm, Wikipedia:Tapetum_lucidum#Classification, PMID:14738502] comment: Taxon notes: cows, sheep, goats and horses[WP] synonym: "fibrous tapetum" RELATED [NCBITaxon:9845, PMID:14738502] is_a: UBERON:0010244 ! choroid tapetum lucidum relationship: only_in_taxon NCBITaxon:9347 ! Eutheria relationship: present_in_taxon NCBITaxon:9788 {source="PMID:14738502", editor="cjm"} ! Equidae relationship: present_in_taxon NCBITaxon:9845 {source="PMID:14738502", editor="cjm"} ! Ruminantia [Term] id: UBERON:0013397 name: stratum argenteum of choroid def: "A silver reflective layer in the outer choroid, adjacent to the sclera, frequently present in fish larvae but not as frequent in adults. In species known to have a stratum argenteum as adults, like the toadfish (Toad- fishes), the tapetum lucidum is absent or vestigial and there is little choroidal melanin." [PMID:14738502] synonym: "choroid stratum argenteum" EXACT [] synonym: "stratum argenteum" BROAD [PMID:14738502] is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001776 ! optic choroid [Term] id: UBERON:0001771 name: pupil def: "sphere that is located in the center of the iris of the eye and that controls the amount of light that enters the eye." [Wikipedia:Pupil] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core xref: FMA:58252 ! Pupil xref: GAID:918 ! pupil xref: VHOG:0000116 ! pupil xref: MA:0001292 ! pupil xref: OpenCyc:Mx4rvViBr5wpEbGdrcN5Y29ycA xref: TAO:0001283 ! pupil xref: XAO:0000283 ! pupil xref: ZFA:0001283 ! pupil xref: ncithesaurus:Pupil ! Pupil xref: OpenCyc:Mx4rvViBr5wpEbGdrcN5Y29ycA ! pupil xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Eye_iris.jpg/200px-Eye_iris.jpg xref: MESH:A09.371.894.513.780 ! pupil is_a: UBERON:0000464 {source="AAO", source="FMA"} ! anatomical space relationship: part_of UBERON:0001769 ! iris xref: AAO:0010351 ! pupil xref: SCTID:35146001 ! Entire pupil xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Eye_iris.jpg property_value: external_definition "The circular orifice in the centre of the iris, through which light enters into the eye. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000116", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {external_class="VHOG:0000116", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0034121 [Term] id: UBERON:0001772 name: corneal epithelium def: "The corneal epithelium (epithelium corneæ anterior layer) is made up of epithelial tissue and covers the front of the cornea. It consists of several layers of cells. The cells of the deepest layer are columnar; then follow two or three layers of polyhedral cells, the majority of which are prickle cells similar to those found in the stratum mucosum of the cuticle. Lastly, there are three or four layers of squamous cells, with flattened nuclei. [WP,unvetted]." [Wikipedia:Corneal_epithelium] comment: Taxon notes: In zebrafish: nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman’s membrane in mammals subset: uberon_slim subset: vertebrate_core synonym: "anterior corneal epithelium" EXACT [] synonym: "epithelium anterius (cornea)" EXACT [] synonym: "epithelium of cornea" EXACT [] synonym: "external epithelium of cornea" EXACT [] synonym: "cornea epithelial tissue" EXACT [OBOL:automatic] synonym: "cornea epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of cornea" EXACT [OBOL:automatic] synonym: "anterior endothelium of cornea" RELATED [BTO:0000287] synonym: "endothelium anterius corneae" RELATED [BTO:0000287] synonym: "endothelium camerae anterioris bulbi" RELATED [BTO:0000287] synonym: "endothelium corneale" RELATED [BTO:0000287] synonym: "epithelium posterius corneae" RELATED [BTO:0000287] xref: BTO:0000287 xref: FMA:58263 ! Corneal epithelium xref: GAID:895 ! corneal epithelium xref: MA:0001243 ! corneal epithelium xref: ZFA:0001683 ! corneal epithelium xref: ncithesaurus:Corneal_Epithelium ! Corneal Epithelium xref: EFO:0001917 ! corneal epithelium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray871.png/200px-Gray871.png xref: EMAPA:17162 ! epithelium of cornea xref: MESH:A09.371.060.217.325 ! corneal epithelium is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000964 ! cornea relationship: part_of UBERON:0000964 ! cornea synonym: "epithelium anterius corneae" EXACT LATIN [FMA:TA, FMA:58263] xref: SCTID:15775008 ! Structure of corneal epithelium xref: EHDAA2:0000319 ! cornea surface epithelium xref: TAO:0002187 ! corneal epithelium synonym: "e. anterius corneae" RELATED LATIN [Wikipedia:Corneal_epithelium] xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png property_value: external_definition "Portion of tissue comprised of four to six layers of nonkeratinized, stratified squamous cells and represents approximately 60% of the thickness of the cornea.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002187", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-061010-3"} xref: UMLS:C0459875 [Term] id: UBERON:0010291 name: layer of sclera def: "." [Wikipedia:Sclera#Histology] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001773 {source="cjm"} ! sclera [Term] id: UBERON:0010292 name: episcleral layer of eyeball def: "The episclera is the outermost layer of the sclera. It is composed of loose, fibrous, elastic tissue and attaches to Tenon's capsule. A vascular plexus is found between the conjunctiva and the sclera consisting of two layers of vessels, the superficial episcleral vessels and the deep episcleral vessels." [Wikipedia:Episcleral_layer] synonym: "episclera" EXACT [FMA:58362] synonym: "episcleral layer" EXACT [FMA:58362] is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera xref: FMA:58362 ! episcleral layer of eyeball xref: ncithesaurus:Episclera ! episclera synonym: "lamina episcleralis" EXACT LATIN [Wikipedia:Episcleral_layer] xref: SCTID:368850003 ! Entire lamina episcleralis xref: UMLS:C0229109 [Term] id: UBERON:0010293 name: suprachoroid lamina def: "On the external surface of the sclera is a thin membrane, the suprachoroid lamina, composed of delicate non-vascular lamellaebeach lamella consisting of a net-work of fine elastic fibers among which are branched pigment cells. The spaces between the lamellC& are lined by endothelium, and open freely into the perichoroidal lymph space, which, in its turn, communicates with the periscleral space by the perforations in the sclera through which the vessels and nerves are transmitted." [Wikipedia:Suprachoroid_lamina] synonym: "fusca sclerae" RELATED [Wikipedia:Suprachoroid_lamina] synonym: "lamina fusca of sclera" EXACT [FMA:58368] synonym: "lamina fusca sclerae" EXACT LATIN [FMA:TA] synonym: "suprachoroid lamina of sclera" EXACT [FMA:58368] synonym: "lamina fusca sclerae" RELATED [Wikipedia:Suprachoroid_lamina] synonym: "lamina fusca scletae" RELATED [Wikipedia:Suprachoroid_lamina] synonym: "lamina suprachorioidea" RELATED [Wikipedia:Suprachoroid_lamina] synonym: "lamina suprachoroidea" RELATED [Wikipedia:Suprachoroid_lamina] is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera xref: FMA:58368 ! suprachoroid lamina synonym: "lamina suprachorioidea" RELATED LATIN [Wikipedia:Suprachoroid_lamina] xref: SCTID:280607003 ! Entire lamina fusca of sclera [Term] id: UBERON:0010321 name: skeletal element of eye region synonym: "eye skeleton" RELATED [] synonym: "ocular skeleton" RELATED [] synonym: "skeletal element of ocular region" RELATED [] intersection_of: UBERON:0004765 ! skeletal element intersection_of: part_of UBERON:0004088 ! ocular region relationship: develops_from UBERON:0002342 {source="PMID:16496288"} ! neural crest relationship: part_of UBERON:0011156 ! facial skeleton def: "A skeletal element that is part of a ocular region." [OBOL:automatic] [Term] id: UBERON:0010326 name: optic pedicel def: "permanent cartilage structure projecting from the site of origin of the recti muscles. Supports eyeball and aids rotation." [ISBN10:071676959X, PMID:16496288] synonym: "eye stalk" RELATED [] is_a: UBERON:0003932 ! cartilaginous elemenet of chondrocranium relationship: part_of UBERON:0004088 ! ocular region relationship: only_in_taxon NCBITaxon:7777 {source="PMID:16496288"} ! Chondrichthyes [Term] id: UBERON:0010294 name: scleral endothelium is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001773 ! sclera def: "An endothelium that is part of a sclera." [OBOL:automatic] [Term] id: UBERON:0010295 name: substantia propria of sclera synonym: "scleral stroma" EXACT [FMA:58365] synonym: "stroma of sclera" EXACT [FMA:58365] synonym: "subsantia propria sclerae" EXACT [FMA:58365] synonym: "subsantia propria" BROAD [] is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0001773 ! sclera xref: FMA:58365 ! substantia propria of sclera xref: ncithesaurus:Substantia_Propria ! substantia propria xref: SCTID:368851004 ! Entire substantia propria of sclera def: "A stroma that is part of a sclera." [OBOL:automatic] xref: UMLS:C1704397 [Term] id: UBERON:0004017 name: periocular mesenchyme def: "the mesenchymal cells that give rise to the corneal endothelium, corneal stroma, sclera, iris stroma, ciliary muscle, ciliary stroma, and trabecular meshwork of the eye[MP]." [MP:0004054, PMID:3709965] comment: AO notes: Check XAO once it has a definition. Taxon notes: Periocular mesenchyme (PM) is a mesencephalic neural crest derived cell population which as a result of an interaction with the retinal pigment epithelium forms the scleral cartilage of the avian eye[PMID:3709965] xref: ZFA:0005572 ! periocular mesenchyme xref: XAO:0004089 ! periocular region synonym: "periocular mesenchyme" RELATED [XAO:0004089] is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0010312 ! immature eye [Term] id: UBERON:0010296 ! scleral skeletal element name: scleral skeletal element comment: An eye adnexal structure, but not necessarily part of the eyeball is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0000019 ! camera-type eye relationship: never_in_taxon NCBITaxon:40674 {source="PMID:17051547"} ! Mammalia relationship: only_in_taxon NCBITaxon:7776 {source="PMID:17051547"} ! Gnathostomata [Term] id: UBERON:0007804 name: sclerotic ring def: "Sclerotic rings are rings of bone found in the eyes of several groups of vertebrate animals, except for mammals and crocodilians. They can be made up of single bones or small bones together. They are believed to have a role in supporting the eye, especially in animals whose eyes are not spherical, or which live underwater. Fossil sclerotic rings are known for a variety of extinct animals, including ichthyosaurs, pterosaurs, and dinosaurs, but are often not preserved[WP]." [Wikipedia:Sclerotic_ring] synonym: "scleral ring" EXACT [Wikipedia:Sclerotic_ring] is_a: UBERON:0010290 {source="PMID:17051547"} ! scleral ossicle relationship: part_of UBERON:0001697 ! orbital region relationship: never_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: UBERON:0010289 name: scleral cartilage def: "Circular cartilage ringing the posterior portion of the eye in the sclera. Supports the eye." [http://www.fishbase.org/glossary/Glossary.php?q=scleral+cartilage] comment: Taxon notes: May be calcified in chondrichthyans. Tetrapods without this element (e.g., snakes and mammals) have a collagenous sclera. May not be homologous - see PMID:17051547. cup-shaped in birds. Present in monotremes. Editor notes: consider distinguishing cup from predecessor of ossicle. Hall: The scleral cartilaginous cup is a distinctly sepa- rate element composed of hyaline cartilage. Editors notes: relationship to sclera - overlaps? synonym: "scleral cartilaginous cup" NARROW SENSU [PMID:17051547] synonym: "sclerotic cartilage" EXACT [ZFA:0001509] synonym: "scleral cartilage element" EXACT [PMID:17051547] xref: TAO:0001509 ! sclerotic cartilage is_a: UBERON:0003932 {source="ZFA"} ! cartilaginous elemenet of chondrocranium is_a: UBERON:0010296 ! scleral skeletal element relationship: part_of UBERON:0001773 {source="cjm"} ! sclera relationship: develops_from UBERON:0002342 {source="PMID:17051547 - ossicles"} ! neural crest relationship: induced_by UBERON:0001782 {gci_relation="part_of", gci_filler="NCBITaxon:9031", notes="Gallus gallus", source="PMID:17051547"} ! pigmented layer of retina relationship: never_in_taxon NCBITaxon:32525 {source="PMID:17051547 - but present in monotremes"} ! Theria xref: ZFA:0001509 ! sclerotic cartilage property_value: external_definition "Bilaterally paired thin continuous band of cartilage that sagitally encircles the eye.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001509", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0010290 ! scleral ossicle name: scleral ossicle def: "A bony plate around the eyes, are situated at the corneal-scleral limbus. They do not articulate with other elements of the skull. Typically, the scleral ossicles overlap the rim of a cup of scleral cartilage that supports the eyeball. Situated near the equator of the eye and may slightly overlap the rim of scleral cartilage." [PMID:17051547] comment: Taxon notes: The distribution of scleral ossicles and scleral cartilage among verte- brate taxa is not the same. Some taxa (e.g., birds) have both elements; some only have one element (e.g., crocodiles only have a scleral cartilage); while others (e.g., snakes) have neither element (Walls, 1942) number of ossicles making up the sclerotic ring as well as the shape of both the individual plates and the sclerotic ring is variable among tetrapod taxa.... It is therefore extremely likely that scleral skeletal elements (ossicles and cartilage) of all rep- tiles (including birds) are homologous (but cannot be assumed for reptiles and teleosts). Function notes: The function of these elements is to support the eye from within the sclera; scleral ossicles play an additional important role during accommodation in terrestrial vertebrates (Lemmrich, 1931; Walls, 1942; King and McLelland, 1984). synonym: "sclerotic bone" EXACT [ZFA:0001411] synonym: "scleral ossicle" EXACT [PMID:17051547] synonym: "sclerotic ossicle" EXACT [] is_a: UBERON:0010296 ! scleral skeletal element relationship: part_of UBERON:0001697 {source="ZFA"} ! orbital region relationship: part_of UBERON:0011156 ! facial skeleton relationship: never_in_taxon NCBITaxon:7777 {source="PMID:17051547 Walls 1942"} ! Chondrichthyes relationship: never_in_taxon NCBITaxon:7878 {source="PMID:17051547 Kemp 1999"} ! Dipnoi xref: SCTID:45632000 ! Scleral ossicle [Term] id: UBERON:0010297 name: endochondral scleral ossicle comment: Taxon notes: The scleral ossicles [of teleosts] are reported to form indirectly by endochondral (Hall and Miyake, 1992) or by perichondral ossification (Patterson, 1977) from a cartilage element that is also present in the sclera. This is unlike the scleral ossicles of reptiles, which develop directly from ectomesenchyme (i.e., intramembranous ossification) and independently from the scleral cartilage[PMID:17051547] is_a: UBERON:0010290 ! scleral ossicle is_a: UBERON:0002513 {source="ZFA"} ! endochondral bone relationship: part_of UBERON:0002241 {source="ZFA"} ! chondrocranium relationship: develops_from UBERON:0010289 {source="ZFA"} ! scleral cartilage relationship: never_in_taxon NCBITaxon:32523 ! Tetrapoda xref: ZFA:0001411 ! sclerotic bone xref: TAO:0001411 ! sclerotic bone property_value: external_definition "A pair of small dish-shaped bones that cap the anterior and posterior margin of the eyeball.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001411", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0010298 ! intramembranous scleral ossicle name: intramembranous scleral ossicle comment: Development notes: The scleral ossicles [in reptiles] are of dermal (neural crest) origin, develop intramembranously within the scleral mesenchyme, and are induced to form by overlying (transient) epithelial scleral papillae (Nelson, 1942; Murray, 1943; Fyfe and Hall, 1981, 1983; Hall, 1981, 2005; Pinto and Hall, 1991) is_a: UBERON:0010290 ! scleral ossicle is_a: UBERON:0002514 {source="PMID:11237469"} ! intramembranous bone relationship: induced_by UBERON:0010300 {source="PMID:16496288"} ! epithelial scleral papilla layer relationship: develops_in UBERON:0010299 ! scleral mesenchyme relationship: never_in_taxon NCBITaxon:32443 ! Teleostei [Term] id: UBERON:0010311 name: scleral sesamoid bone def: "A sesamoid bone that lies adjacent to the tendon of one of the muscles responsible for adducting the nictitating membrane (the pyramidal nictitating muscle) " [PMID:16496288] comment: Structure notes: During contraction, the scleral sesamoid bone acts to anchor the pyramidal nictitating muscle to the sclera and divert the tendon from pro- jecting over the cornea. It remains to be determined whether this is indeed a true sesamoid (sensu; Vickaryous and Olson, 2006), as the scleral sesa- moid is actually invested within the synovial tendon sheath and not the tendon per se synonym: "sesamoideum esclerae" EXACT [PMID:16496288] synonym: "scleral sesamoid" EXACT [PMID:16496288] synonym: "scleral sesamoid element" EXACT [] is_a: UBERON:0001479 ! sesamoid bone is_a: UBERON:0010290 ! scleral ossicle relationship: only_in_taxon NCBITaxon:30458 ! Strigiformes [Term] id: UBERON:0010308 name: os opticus def: "Scleral element located at the posterior pole of the scleral cartilage surrounding the foramen through which the optic nerve fibers pass. the internal architecture of this bone reveals a cancellous marrow cavity with fatty tissue." [PMID:16496288] comment: Taxon notes: At present, it has been documented in 219 species from 35 families, including perching birds, woodpeckers, hummingbirds, toucans, kingfishers, and falcons (Tiemeier, 1950). Morphologically, this element varies in shape from a complete encircling element in some woodpeckers (e.g., Melanerpes eryth- rocephalus) to an abbreviated arc in Gallus is_a: UBERON:0010298 ! intramembranous scleral ossicle synonym: "os nervi optici" EXACT [PMID:16496288] synonym: "Gemminger's ossicle" EXACT [PMID:16496288] [Term] id: UBERON:0010299 ! scleral mesenchyme name: scleral mesenchyme def: "Mesenchyme surrounding the developing optic cup which develops into the sclera." [PMID:16496288, UBERON:cjm] comment: Development notes: The mesenchyme surrounding the developing optic cup differentiates into the sclera, the dense fibrous coat of the eye.. PMID:16496288 is_a: UBERON:0003104 ! mesenchyme [Term] id: UBERON:0010300 ! epithelial scleral papilla layer name: epithelial scleral papilla layer synonym: "scleral papillae" EXACT [] comment: Development notes: The scleral ossicles are of dermal (neural crest) origin, develop intramembranously within the scleral mesenchyme, and are induced to form by overlying (transient) epithelial scleral papillae (Nelson, 1942; Murray, 1943; Fyfe and Hall, 1981, 1983; Hall, 1981, 2005; Pinto and Hall, 1991). Taxon notes: Scleral papillae (which induce scleral ossicles in birds) have not been reported in teleosts, but evidence for their presence may not have been sought is_a: UBERON:0000483 ! epithelium relationship: develops_in UBERON:0010299 ! scleral mesenchyme [Term] id: UBERON:0001773 name: sclera def: "Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]." [Wikipedia:Sclera, ZFIN:ZDB-PUB-050701-15] comment: Development notes: Majority derives from NC that surrounds optic cup of neurectoderm; a small temporal portion develops from the mesoderm that contributes to striated extra-ocular muscles and vascular endothelia[Rada&Johnson]. Taxon notes: Multi-tissue structure that composes the opaque fibrous outer layer of the eye[ZFA] Seko et al demonstrate chondrogenic potential doi:10.1371/journal.pone.0003709 and identify this as connective tissue. Disease notes: implicated in rheumatoid arthritis. Structure notes: continuous with the dura mater and the cornea; The sclera forms the posterior five-sixths of the connective tissue coat of the globe. Taxon notes: in fish, reptiles and monotremes the connective tissue of the sclera is skeletal synonym: "scleral capsule" RELATED [] subset: uberon_slim subset: vertebrate_core xref: FMA:58269 ! Sclera xref: GAID:911 ! sclera xref: VHOG:0001274 ! sclera xref: MA:0000280 ! sclera xref: OpenCyc:Mx4rv7yR55wpEbGdrcN5Y29ycA xref: XAO:0000183 ! sclera xref: ncithesaurus:Sclera ! Sclera xref: BTO:0001606 ! sclera xref: OpenCyc:Mx4rv7yR55wpEbGdrcN5Y29ycA ! sclera xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: EMAPA:19027 ! sclera xref: MESH:A09.371.784 ! sclera xref: ZFA:0005563 ! sclera xref: EV:0100342 ! sclera xref: ncithesaurus:Sclera ! sclera is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0012430 {source="FMA"} ! tunica fibrosa of eyeball relationship: has_part CL:0000347 {source="ZFA"} ! scleral cell relationship: has_developmental_contribution_from UBERON:0002342 {source="Wikipedia"} ! neural crest relationship: has_developmental_contribution_from UBERON:0000926 {source="cjm"} ! mesoderm xref: AAO:0010354 ! sclera xref: SCTID:181163006 ! Entire sclera xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg property_value: external_definition "The tough, usually white, outer coat of the eyeball, covering all the posterior surface and continuous anteriorly with the cornea. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001274", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/sclera", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "scleral" xsd:string xref: UMLS:C0036410 property_value: external_definition "The sclera, also known as the white part of the eye, is the opaque (usually white, though certain animals, such as horses and lizards, can have black sclera), fibrous, protective, outer layer of the eye containing collagen and elastic fiber. It is derived from the neural crest. In children, it is thinner and shows some of the underlying pigment, appearing slightly blue. In the elderly, however, fatty deposits on the sclera can make it appear slightly yellow. The sclera forms the posterior five sixths of the connective tissue coat of the globe. It is continuous with the dura mater and the cornea, and maintains the shape of the globe, offering resistance to internal and external forces, and provides an attachment for the extraocular muscle insertions. The sclera is perforated by plenty of nerves and vessels passing through the posterior scleral foramen, the hole that is formed by the optic nerve. At the optic disk the outer two-thirds of the sclera continues with the dura mater (outer coat of the brain) via the dural sheath of the optic nerve. The inner third joins with some choroidal tissue to form a plate (lamina cribrosa) across the optic nerve with perforations through which the optic fibers (fasciculi). The thickness of the sclera varies from 1mm at the posterior pole to 0.3 mm just behind the rectus muscle insertions. The sclera's blood vessels are mainly on the surface, and together with the conjunctiva (which lies on top) This is a thin layer covering the sclera. Along with the vessels of the conjunctiva, those of the sclera renders the inflamed eye bright red. [WP,unvetted][Wikipedia:Sclera]." xsd:string {source="Wikipedia:Sclera"} [Term] id: UBERON:0001774 name: muscle of trunk def: "Muscle organ which is a part of the trunk. Examples: external intercostal muscle, external oblique, levator ani." [] comment: TODO - check muscle organ vs musculature subset: uberon_slim subset: vertebrate_core synonym: "trunk muscle" EXACT [] synonym: "trunk musculature" EXACT [] synonym: "muscle organ of torso" EXACT [OBOL:automatic] synonym: "muscle organ of trunk" EXACT [OBOL:automatic] synonym: "torso muscle organ" EXACT [OBOL:automatic] synonym: "trunk muscle organ" EXACT [OBOL:automatic] synonym: "body musculature" EXACT [ZFA:0000473] xref: XAO:0003230 ! trunk musculature xref: ZFA:0000473 ! trunk musculature xref: AAO:0000611 ! trunk_muscles xref: FMA:58274 ! Muscle of trunk xref: MA:0000514 ! trunk muscle xref: EFO:0003531 ! trunk musculature (also: UBERON:0004479 'musculature of trunk') is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002100 ! trunk xref: TAO:0000473 ! trunk musculature [Term] id: UBERON:0001777 name: substantia propria of cornea def: "The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamellæ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamellæ interweaving more than posterior lamellæ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamellæ. The lamellæ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamellæ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "cornea stroma" EXACT [] synonym: "corneal stroma" EXACT [] synonym: "stroma of cornea" EXACT [] synonym: "substantia propria" RELATED [] xref: FMA:58306 ! Substantia propria of cornea xref: GAID:893 ! corneal stroma xref: MA:0001245 ! corneal stroma xref: ZFA:0001685 ! corneal stroma xref: ncithesaurus:Corneal_Stroma ! Corneal Stroma xref: EFO:0002514 ! corneal stroma xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray871.png/200px-Gray871.png xref: EMAPA:17602 ! stroma xref: MESH:A09.371.060.217.228 ! corneal stroma intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0000964 ! cornea relationship: develops_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest xref: SCTID:362511000 ! Entire substantia propria of cornea xref: TAO:0002189 ! corneal stroma property_value: external_definition "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002189", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-061010-3"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass tissue (CARO:0000043) CHANGED TO: develops_from tissue (UBERON:0000479)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002189", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass tissue (CARO:0000043) CHANGED TO: has_developmental_contribution_from tissue (UBERON:0000479)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002189", date_retrieved="2012-08-14"} xref: UMLS:C0010040 [Term] id: UBERON:0001779 name: iris stroma def: "the delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae." [http://www.drugs.com/dict/stroma-of-iris.html, Wikipedia:Iris_stroma] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "iridial stroma" EXACT [] synonym: "stroma of iris" EXACT [] xref: FMA:58526 ! Stroma of iris xref: MA:0002777 ! iris stroma xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray883.png/200px-Gray883.png xref: ZFA:0005569 ! iris stroma is_a: UBERON:0003891 ! stroma relationship: part_of UBERON:0001769 ! iris xref: SCTID:280882008 ! Entire stroma of iris [Term] id: UBERON:0006762 name: suspensory ligament of lens def: "The zonule of Zinn (Zinn's membrane, ciliary zonule) is a ring of fibrous strands connecting the ciliary body with the crystalline lens of the eye. The zonule of Zinn is split into two layers: a thin layer, which lines the hyaloid fossa, and a thicker layer, which is a collection of zonular fibers. Together, the fibers are known as the suspensory ligament of the lens[WP]. Modified or toughened vitreous that suspend the lens at the equator to the non-pigmented epithelium of the ciliary zone. In zebrafish, dorsal zonules are thickened as compared to ventral zonules. In both dorsal and ventral regions, these fibers delimit the vitreous body aqueous humor boundary[ZFA]." [Wikipedia:Zonule_of_Zinn] subset: vertebrate_core synonym: "ciliary zonule" RELATED [Wikipedia:Zonule_of_Zinn] synonym: "suspensory ligament of the lens" RELATED [Wikipedia:Zonule_of_Zinn] synonym: "zonula" RELATED [Wikipedia:Zonule_of_Zinn] synonym: "zonula ciliaris" RELATED [Wikipedia:Zonule_of_Zinn] synonym: "zonular fiber" RELATED [Wikipedia:Zonule_of_Zinn] synonym: "zonule" RELATED [Wikipedia:Zonule_of_Zinn] synonym: "ciliary zonule" EXACT [FMA:58838] synonym: "Zinn's membrane" EXACT [FMA:58838] synonym: "zonule of Zinn" EXACT [FMA:58838] synonym: "zonules" EXACT PLURAL [ZFA:0005573] xref: FMA:58838 ! suspensory ligament of lens xref: ZFA:0005573 ! zonule is_a: UBERON:0008841 {source="Obol"} ! suspensory ligament relationship: develops_from UBERON:0001797 {source="ZFA"} ! vitreous humor relationship: continuous_with UBERON:0001775 ! ciliary body relationship: continuous_with UBERON:0000965 ! lens relationship: part_of UBERON:0000019 {source="FMA"} ! camera-type eye xref: SCTID:362524000 ! Entire suspensory ligament of lens synonym: "zonula ciliaris" RELATED LATIN [Wikipedia:Zonule_of_Zinn] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg [Term] id: UBERON:0006761 name: corneo-scleral junction def: "The corneal limbus is the border of the cornea and the sclera (the white of the eye). The limbus is a common site for the occurrence of corneal epithelial neoplasm. Limbus contains radially oriented fibrovascular ridges known as the palisades of Vogt that may harbour a stem cell population[WP]. An annular transitional zone, approximately 1 mm wide, between the cornea and the bulbar conjunctiva and sclera. It is highly vascular and is involved in the metabolism of the cornea. It is ophthalmologically significant in that it appears on the outer surface of the eyeball as a slight furrow, marking the line between the clear cornea and the sclera. (Dictionary of Visual Science, 3d ed)[MeSH]" [Wikipedia:Corneal_limbus] comment: This location has parts such as blood vessels etc. See PMC2868485, PMID:2695343 subset: vertebrate_core synonym: "limbus corneae" RELATED [Wikipedia:Corneal_limbus] synonym: "corneal limbus" RELATED [GAID:896] synonym: "corneoscleral junction" RELATED [GAID:896] synonym: "corneal-scleral limbus" EXACT [PMID:17051547] synonym: "sclerocorneal limbus" RELATED [GAID:896] synonym: "corneal limbus" EXACT [FMA:58342] synonym: "sclerocorneal junction" EXACT [FMA:58342] xref: ZFA:0005570 ! corneo-scleral junction xref: GAID:896 ! limbus corneae xref: FMA:58342 ! corneoscleral junction xref: MESH:A09.371.060.217.659 ! limbus corneae xref: EFO:0001403 ! corneal limbus intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0001773 ! sclera intersection_of: connects UBERON:0000964 ! cornea xref: SCTID:63716004 ! Sclerocorneal junction synonym: "limbus corneae" RELATED LATIN [Wikipedia:Corneal_limbus] xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Limbus.png [Term] id: UBERON:0001780 name: spinal nerve def: "Neural tree (organ) which is directly continuous with the spinal cord. Examples: Fifth cervical spinal nerve, third lumbar spinal nerve." [Wikipedia:Spinal_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "spinal nerve tree" EXACT [] synonym: "backbone nerve" EXACT [OBOL:automatic] synonym: "nerve of backbone" EXACT [OBOL:automatic] synonym: "nerve of spinal column" EXACT [OBOL:automatic] synonym: "nerve of spine" EXACT [OBOL:automatic] synonym: "nerve of vertebral column" EXACT [OBOL:automatic] synonym: "spinal column nerve" EXACT [OBOL:automatic] synonym: "spine nerve" EXACT [OBOL:automatic] synonym: "vertebral column nerve" EXACT [OBOL:automatic] xref: BTO:0000870 xref: FMA:5858 ! Spinal nerve xref: GAID:841 ! spinal nerve xref: VHOG:0000824 ! spinal nerve xref: MA:0000233 ! spinal nerve xref: XAO:0003101 ! spinal nerve xref: ncithesaurus:Spinal_Nerve ! Spinal Nerve xref: OpenCyc:Mx4rwK_iFJwpEbGdrcN5Y29ycA ! spinal nerve xref: EHDAA2:0001898 ! spinal nerve xref: EMAPA:16989 ! nerve of spinal xref: MESH:A08.800.800.720 ! spinal nerve is_a: UBERON:0001021 ! nerve relationship: continuous_with UBERON:0002240 ! spinal cord relationship: part_of UBERON:0000010 ! peripheral nervous system xref: AAO:0011101 ! spinal nerve xref: SCTID:361099009 ! Entire spinal nerve synonym: "nervi spinales" RELATED LATIN [Wikipedia:Spinal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg property_value: external_definition "Any of the paired nerves emerging from the spinal cord, each attached to the cord by two roots: ventral and dorsal, and passing out between the vertebrae. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000824", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/spinal+nerve", source="http://bgee.unil.ch/"} xref: UMLS:C0037941 [Term] id: UBERON:0001783 name: optic disc def: "The optic disc or optic nerve head is the location where ganglion cell axons exit the eye to form the optic nerve. There are no light sensitive rods or cones to respond to a light stimulus at this point. This causes a break in the visual field called 'the blind spot' or the 'physiological blind spot'. The optic nerve head in a normal human eye carries from 1 to 1.2 million neurons from the eye towards the brain. [WP,unvetted]." [Wikipedia:Optic_disc] synonym: "optic disk" EXACT [MESH:A08.800.800.120.680.660] synonym: "optic disk" RELATED [Wikipedia:Optic_disc] synonym: "optic nerve disc" RELATED [Wikipedia:Optic_disc] synonym: "optic nerve head" RELATED [Wikipedia:Optic_disc] synonym: "optic papilla" RELATED [Wikipedia:Optic_disc] synonym: "physiologic blind spot" RELATED [Wikipedia:Optic_disc] synonym: "physiologic blind spot of mariotte" RELATED [Wikipedia:Optic_disc] subset: uberon_slim xref: EHDAA:9077 ! optic disc xref: FMA:58634 ! Optic disc xref: VHOG:0000551 ! optic disc xref: MA:0000278 ! optic disc xref: ncithesaurus:Optic_Disc ! Optic Disc xref: EFO:0001974 ! optic disc xref: EHDAA2:0001307 ! optic disc xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Gray879.png/200px-Gray879.png xref: EMAPA:25088 ! optic disc of optic stalk xref: EMAPA:18238 ! optic disc of retina is_a: UBERON:0000064 ! organ part xref: MESH:A08.800.800.120.680.660 ! optic disk relationship: part_of UBERON:0000966 ! retina relationship: continuous_with UBERON:0000941 ! cranial nerve II xref: SCTID:362518006 ! Entire optic disc xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Gray879.png property_value: external_definition "The small blind spot on the surface of the retina. It is the point where the fibers of the retina leave the eye and become part of the optic nerve. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000551", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/optic+disc", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000551", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.424 and p.426 and p.429 and Figure 12-24", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0029127 [Term] id: UBERON:0001784 name: obsolete macula lutea comment: Obsoleted as it accidentally grouped macula and macula lutea is_obsolete: true consider: UBERON:0000053 consider: UBERON:0000054 [Term] id: UBERON:0011779 name: nerve of head region subset: grouping_class synonym: "cephalic nerve" RELATED [] synonym: "head nerve" RELATED [] intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000033 ! head def: "A nerve that is part of a head." [OBOL:automatic] [Term] id: UBERON:0001785 name: cranial nerve def: "Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord. In humans, there are traditionally twelve pairs of cranial nerves. Only the first and the second pair emerge from the cerebrum; the remaining ten pairs emerge from the brainstem[WP]." [Wikipedia:Cranial_nerve] comment: Editors note: classified as neural tree organ, not nerve in FMA. CN II poses a challenge here as it is not strictly a nerve, yet is expected to be classified under CN. Note EMAPA subdivides nerve into CNS nerve and PNS nerve, with *all* cranial nerves classified as CNS nerves. subset: uberon_slim subset: vertebrate_core synonym: "cranial nerves" RELATED [] synonym: "cranial neural tree organ" EXACT [] xref: BTO:0001104 xref: FMA:5865 ! Cranial nerve xref: GAID:802 ! cranial nerve xref: VHOG:0000279 ! cranial nerve xref: MA:0000215 ! cranial nerve xref: NIF_GrossAnatomy:birnlex_1623 ! Cranial nerve xref: OpenCyc:Mx4rvWvJVpwpEbGdrcN5Y29ycA xref: TAO:0000641 ! cranial nerve xref: XAO:0000429 ! cephalic nerve xref: AAO:0000108 ! cranial_nerves xref: XAO:0003089 ! cranial nerve xref: ZFA:0000641 ! cranial nerve xref: ncithesaurus:Cranial_Nerve ! Cranial Nerve xref: OpenCyc:Mx4rvWvJVpwpEbGdrcN5Y29ycA ! cranial nerve xref: EHDAA2:0000323 ! cranial nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Brain_human_normal_inferior_view_with_labels_en.svg/200px-Brain_human_normal_inferior_view_with_labels_en.svg.png xref: EMAPA:17264 ! cranial of nerve of central nervous system of nervous system of organ system xref: EMAPA:17263 ! nerve of central nervous system of nervous system of organ system xref: MESH:A08.800.800.120 ! cranial nerve is_a: UBERON:0001021 ! nerve relationship: in_lateral_side_of UBERON:0000010 ! peripheral nervous system relationship: continuous_with UBERON:0000955 ! brain relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest xref: SCTID:244447006 ! Entire cranial nerve synonym: "nervus cranialis" RELATED LATIN [Wikipedia:Cranial_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/1/18/Brain_human_normal_inferior_view_with_labels_en-2.svg property_value: external_definition "Twelve pairs of cranial nerves exit/enter the cranium through openings in the skull. The nerves contain efferent axons with motor and glandular functions, as well as afferent axons from cranial ganglia with sensory functions. The nerves are numbered in a rostral to caudal sequence, with the exception of the lateral line nerves.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000641", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000279", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0010268 [Term] id: UBERON:0001786 name: fovea centralis def: "a part of the eye, located in the center of the macula region of the retina. [1] [2] The fovea is responsible for sharp central vision (also called foveal vision). The fovea is surrounded by the parafovea belt, and the perifovea outer region:[2] the parafovea is the intermediate belt where the ganglion cell layer is composed of more than five rows of cells; as well as the highest density of cones; the perifovea is the outermost region where the ganglion cell layer contains two to four rows of cells, and is where visual acuity is below the optimum. The perifovea contains an even more diminished density of cones, having 12 per 100 micrometres versus 50 per 100 micrometres in the most central fovea. This, in turn, is surrounded by a larger peripheral area that delivers highly compressed information of low resolution. Approximately 50% of the nerve fibers in the optic nerve carry information from the fovea, while the other 50% carry information from the rest of the retina. The parafovea extends to a distance of 1¼ mm from the central fovea, and the perifovea is found 2¾ mm away from the fovea centralis[WP]." [Wikipedia:Fovea_centralis_in_macula] comment: As an anatomical term, there are several foveae around the body, including in the head of the femur.(WP) subset: uberon_slim synonym: "fovea" EXACT [] synonym: "fovea centralis in macula" EXACT [Wikipedia:Fovea_centralis_in_macula] synonym: "centre of macula" EXACT [NIF_GrossAnatomy:birnlex_2543] xref: FMA:58658 ! Fovea centralis xref: GAID:910 ! fovea centralis xref: MA:0001307 ! fovea xref: NIF_GrossAnatomy:birnlex_2543 ! Fovea xref: ncithesaurus:Fovea_Centralis ! Fovea Centralis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: MESH:A09.371.729.522.436 ! fovea centralis xref: EV:0100350 ! fovea centralis is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000053 ! macula lutea relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: SCTID:264479005 ! Entire fovea centralis xref: VHOG:0001572 ! fovea property_value: external_definition "A small pit in the center of the macula lutea, the area of clearest vision, where the retinal layers are spread aside, and light falls directly on the cones. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001572", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/fovea", source="http://bgee.unil.ch/"} property_value: homology_notes "Definition of fovea centralis should be considered here as 'an area centralis at the visual axis' (reference 1). There is an uncertaincy of the relation, because: 1.-The fovea first appeared in evolution in the temporal retina of fishes. Then, in birds, the nasal fovea and bifoveal system with nasal and temporal foveas developed. The fovea disappeared in primitive mammals, and reappeared in primates. A residue of the fovea is conserved in the visual streak, and the disappearance and reappearance of the fovea, in primitive mammals and primates respectively, correlates with degeneration and restoration of cone pigment genes in photoreceptors (reference 2). 2.-Many retinal features (foveas, trichromacy, midget pathways and associated cell types) appear specific to primates. This has led to investigations in parallel with other mammalian models such as cat or rabbit. Correlation of the results often proves to be difficult, since an evolutionary scenario with transitions between the mammalian models is largely lacking (reference 3).[uncertain][VHOG]" xsd:string {external_class="VHOG:0001572", ontology="VHOG", source="DOI:10.1017/S095252380623342X Ahnelt PK\, Schubert C\, Kübber-Heiss A\, Schiviz A\, Anger E\, Independent variation of retinal S and M cone photoreceptor topographies: A survey of four families of mammals. Visual neuroscience (2006)\, PMID:11193946 Azuma N\, Molecular cell biology on morphogenesis of the fovea and evolution of the central vision. Nihon Ganka Gakkai Zasshi (2000)\, DOI:10.1016/S1350-9462(00)00012-4 Ahnelt PK\, Kolb H\, The mammalian photoreceptor mosaic-adaptive design. Progress in Retinal and Eye Research (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0016622 [Term] id: UBERON:0001781 name: layer of retina def: "any of the layers that make up the retina[MP]." [MP:0003727] comment: Note that MA does not treat internal/external limiting memranes as layers - these are classified as laminae. Here we follow other ontologies in grouping with other layers. MA also treats retinal pigment epithelium and neural retina epithelium as distinct from the layers. We follow ontologies such as FMA and ZFA in first dividing into pigmented and neural layers - these are also classified as layers, giving us over the usual 10 layers subset: vertebrate_core synonym: "retina layer" EXACT [] synonym: "retinal layer" EXACT [] synonym: "retinal neuronal layer" EXACT [MP:0006069] synonym: "retina neuronal layer" EXACT [MP:0006069] xref: FMA:58617 ! Layer of retina xref: MA:0001319 ! retina layer xref: XAO:0000266 ! retinal layer xref: ncithesaurus:Retina_Layer ! Retina Layer is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0000966 ! retina xref: AAO:0010353 ! retinal layer xref: SCTID:280657006 ! Layer of retina xref: UMLS:C0459649 [Term] id: UBERON:0008921 ! substratum of layer of retina name: substratum of layer of retina def: "." [UBERON:CL_meeting_20110725, http://retina.anatomy.upenn.edu/~lance/eye/retina_gross.html] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0000966 ! retina [Term] id: UBERON:0007619 ! limiting membrane of retina name: limiting membrane of retina comment: MA does treat internal/external limiting membranes as layers - these are classified as laminae. We do not follow this convention. However, we do following MA is grouping these terms together subset: grouping_class synonym: "retina lamina" EXACT [MA:0001318] xref: MA:0001318 ! retina lamina is_a: UBERON:0001781 {source="UBERON"} ! layer of retina relationship: part_of UBERON:0003902 ! retinal neural layer xref: SCTID:280667001 ! Limiting membrane of retina [Term] id: UBERON:0001782 ! pigmented layer of retina name: pigmented layer of retina def: "A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup[ZFA]. the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells[WP]." [Wikipedia:Retinal_pigment_epithelium, ZFIN:curator] comment: editor note - we follow ontologies such as FMA and ZFA in first dividing into pigmented and neural layers subset: uberon_slim subset: vertebrate_core synonym: "outer pigmented layer of retina" EXACT [] synonym: "pigment epithelium of retina" EXACT [] synonym: "pigmented epithelium" RELATED [] synonym: "pigmented retina" RELATED [] synonym: "pigmented retinal epithelium" EXACT [] synonym: "pigmented retina epithelium" EXACT [] synonym: "PRE" RELATED [] synonym: "retinal pigment epithelium" EXACT [MP:0005201, Wikipedia:Retinal_pigment_epithelium] synonym: "retinal pigmented epithelium" EXACT [] synonym: "RPE" RELATED [] synonym: "stratum pigmentosum (retina)" EXACT [] synonym: "retinal pigmented epithelium" EXACT [ZFA:0000144] synonym: "epithelium, retinal pigment" RELATED [BTO:0001177] xref: BTO:0001177 xref: EHDAA:4765 ! pigmented retinal epithelium xref: FMA:58627 ! Pigmented layer of retina xref: VHOG:0000536 ! pigmented retinal epithelium xref: MA:0000279 ! pigmented retinal epithelium xref: TAO:0000144 ! retinal pigmented epithelium xref: ZFA:0000144 ! retinal pigmented epithelium xref: XAO:0003217 ! retinal pigmented epithelium xref: ncithesaurus:Retinal_Pigment_Epithelium ! Retinal Pigment Epithelium xref: EHDAA2:0001465 ! pigmented retinal epithelium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray881.png/200px-Gray881.png xref: EMAPA:17172 ! pigmented retinal epithelium is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0001781 ! layer of retina intersection_of: develops_from UBERON:0005424 ! presumptive retinal pigmented epithelium relationship: adjacent_to UBERON:0003902 ! retinal neural layer relationship: adjacent_to UBERON:0001787 {source="Wikipedia"} ! photoreceptor layer of retina relationship: has_part GO:0048770 ! pigment granule xref: AAO:0011096 ! retinal pigmented epithelium xref: SCTID:280662007 ! Entire retinal pigment epithelium synonym: "stratum pigmentosa retinae, p. pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png property_value: external_definition "The monolayer of pigmented epithelium covering the neural retina.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011096", date_retrieved="2012-06-20", source="ZFA:0000144"} property_value: external_definition "A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000144", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "retinal pigment layer" RELATED [VHOG:0000536] property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0000536", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0035322 [Term] id: UBERON:0003902 ! retinal neural layer name: retinal neural layer def: "The part of the retina that contains neurons and photoreceptor cells[GO]." [GO:0003407] comment: editor note - we follow ontologies such as FMA and ZFA in first dividing into pigmented and neural layers; the neural layers are further divided into 9 layers. Note that in MA this class is a leaf node. subset: vertebrate_core synonym: "neural layer of retina" EXACT [FMA:58628] synonym: "neural retina" EXACT [XAO:0003216, ZFA:0000046] synonym: "neuroretina" EXACT [ZFA:0000046] synonym: "neural retinal epithelium" RELATED [MA:000027] synonym: "stratum nervosum (retina)" EXACT [FMA:58628] xref: XAO:0003216 ! retinal neural layer xref: ZFA:0000046 ! retinal neural layer xref: BTO:0000929 ! neural retina xref: ncithesaurus:Neural_Retina ! Neural Retina xref: VHOG:0000535 ! neural retinal epithelium xref: MA:0000277 ! neural retinal epithelium xref: FMA:58628 ! neural layer of retina xref: EHDAA2:0001253 ! neural retinal epithelium xref: EMAPA:17171 ! neural retinal epithelium xref: EMAPA:18590 ! neural retina xref: EHDAA:4763 ! neural retinal epithelium intersection_of: UBERON:0001781 ! layer of retina intersection_of: develops_from UBERON:0005425 ! presumptive neural retina relationship: has_part CL:0000540 ! neuron relationship: induced_by UBERON:0005426 ! lens vesicle xref: AAO:0011095 ! retinal neural layer xref: TAO:0000046 ! retinal neural layer property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0000535", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1518263 [Term] id: UBERON:0001787 ! photoreceptor layer of retina name: photoreceptor layer of retina def: "The layer within the retina where the photoreceptor cell receptor segments reside." [ZFA:0000143, Wikipedia:Layer_of_rods_and_cones] comment: we follow MA and ZFA in subdividing this into inner and outer segments subset: uberon_slim subset: vertebrate_core synonym: "layer of rods and cones" RELATED [] synonym: "retina photoreceptor layer" EXACT [] synonym: "stratum segmentorum externorum et internorum (retina)" EXACT [] synonym: "retinal photoreceptor layer" EXACT [ZFA:0000143] xref: FMA:58680 ! Photoreceptor layer of retina xref: MA:0001308 ! retina photoreceptor layer xref: XAO:0003215 ! photoreceptor layer xref: ZFA:0000143 ! retinal photoreceptor layer xref: VHOG:0001165 ! retinal photoreceptor layer xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray881.png/200px-Gray881.png is_a: UBERON:0001781 ! layer of retina relationship: part_of UBERON:0003902 ! retinal neural layer relationship: has_part CL:0000287 {source="ZFA"} ! eye photoreceptor cell relationship: adjacent_to UBERON:0001788 ! outer limiting layer of retina xref: ncithesaurus:Layer_of_the_Rods_and_Cones ! Layer of the Rods and Cones xref: TAO:0000143 ! retinal photoreceptor layer xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001165", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229206 [Term] id: UBERON:0003925 name: photoreceptor inner segment layer def: "Layer of the retina composed of the inner segments of the photoreceptor cells." [ZFIN:curator] subset: vertebrate_core synonym: "retina photoreceptor layer inner segment" EXACT [MA:0002471] xref: MA:0002471 ! retina photoreceptor layer inner segment xref: ZFA:0001465 ! photoreceptor inner segment layer xref: VHOG:0001172 ! retina photoreceptor layer inner segment is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0001787 {source="MA"} ! photoreceptor layer of retina relationship: adjacent_to UBERON:0001788 ! outer limiting layer of retina relationship: has_part GO:0001917 ! photoreceptor inner segment xref: TAO:0001465 ! photoreceptor inner segment layer property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001172", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003926 name: photoreceptor outer segment layer subset: vertebrate_core synonym: "retina photoreceptor layer outer segment" EXACT [MA:0002472] xref: MA:0002472 ! retina photoreceptor layer outer segment xref: ZFA:0001466 ! photoreceptor outer segment layer xref: VHOG:0001173 ! retina photoreceptor layer outer segment is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0001787 {source="MA"} ! photoreceptor layer of retina relationship: adjacent_to UBERON:0001782 ! pigmented layer of retina relationship: has_part GO:0001750 ! photoreceptor outer segment xref: TAO:0001466 ! photoreceptor outer segment layer property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001173", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001788 ! outer limiting layer of retina name: outer limiting layer of retina def: "the row of jucntional complexes between the plasma membranes of rod segments and the Muller glia cells; this barrier separates the layer of inner and outer segments of the rods and cones from the outer nuclear layer and forms a blood-retina barrier[MP]." [MP:0010236] subset: vertebrate_core synonym: "external limiting lamina of retina" EXACT [] synonym: "external limiting membrane of retina" EXACT [] synonym: "outer limiting membrane of retina" EXACT [] synonym: "retina external limiting lamina" EXACT [] synonym: "stratum limitans externum (retina)" EXACT [] synonym: "retina outer limiting membrane" EXACT [MP:0010236] synonym: "outer limiting membrane" EXACT [XAO:0003224] synonym: "external limiting membrane" EXACT [ZFA:0001331] xref: FMA:58683 ! Outer limiting layer of retina xref: MA:0001309 ! retina external limiting lamina xref: XAO:0003224 ! outer limiting membrane xref: ZFA:0001331 ! outer limiting membrane is_a: UBERON:0007619 {source="MA"} ! limiting membrane of retina relationship: adjacent_to UBERON:0001789 ! outer nuclear layer of retina xref: ncithesaurus:Outer_Limiting_Membrane ! Outer Limiting Membrane xref: SCTID:280676008 ! Entire external limiting membrane of retina xref: TAO:0001331 ! outer limiting membrane xref: UMLS:C1518685 [Term] id: UBERON:0001789 ! outer nuclear layer of retina name: outer nuclear layer of retina def: "The layer within the retina where the photoreceptor cell bodies reside." [ZFA:0001464] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "ONL" NARROW [] synonym: "outer nuclear layer" BROAD [] synonym: "retina outer nuclear layer" EXACT [] synonym: "stratum nucleare externum (retina)" EXACT [] synonym: "retinal outer nuclear layer" EXACT [] xref: FMA:58684 ! Outer nuclear layer of retina xref: MA:0001315 ! retina outer nuclear layer xref: ZFA:0001464 ! retinal outer nuclear layer xref: XAO:0003219 ! retinal outer nuclear layer xref: VHOG:0001170 ! retinal outer nuclear layer xref: EMAPA:19157 ! outer nuclear layer is_a: UBERON:0001781 ! layer of retina relationship: part_of UBERON:0003902 ! retinal neural layer relationship: overlaps CL:0000287 {source="ZFA", notes="soma"} ! eye photoreceptor cell relationship: adjacent_to UBERON:0001790 ! outer plexiform layer of retina xref: SCTID:280678009 ! Entire outer nuclear layer of retina xref: ncithesaurus:Outer_Nuclear_Layer_of_Retina ! Outer Nuclear Layer xref: TAO:0001464 ! retinal outer nuclear layer property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001170", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229210 [Term] id: UBERON:0001790 ! outer plexiform layer of retina name: outer plexiform layer of retina def: "The layer within the retina where the bipolar cells synapse with the photoreceptor cells[ZFA]. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells[GO]." [ZFA:0001330] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "OPL" NARROW [] synonym: "retina outer plexiform layer" EXACT [] synonym: "retinal outer plexiform layer" EXACT [] synonym: "stratum plexiforme externum" EXACT [] synonym: "outer plexiform layer" EXACT [BTO:0003174] synonym: "external plexiform layer" BROAD [BTO:0003174] xref: FMA:58685 ! Outer plexiform layer of retina xref: MA:0001316 ! retina outer plexiform layer xref: ZFA:0001330 ! retinal outer plexiform layer xref: XAO:0003218 ! retinal outer plexiform layer xref: BTO:0003174 ! outer plexiform layer xref: VHOG:0001171 ! retinal outer plexiform layer is_a: UBERON:0001781 ! layer of retina relationship: part_of UBERON:0003902 ! retinal neural layer relationship: adjacent_to UBERON:0001791 ! inner nuclear layer of retina xref: ncithesaurus:Outer_Plexiform_Layer ! Outer Plexiform Layer xref: SCTID:280684007 ! Entire outer plexiform layer of retina xref: TAO:0001330 ! retinal outer plexiform layer property_value: external_definition "The layer within the retina where the bipolar cells synapse with the photoreceptor cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001330", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001171", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229217 [Term] id: UBERON:0001791 ! inner nuclear layer of retina name: inner nuclear layer of retina def: "The layer of the retina composed of the cell bodies of bipolar cells, horizontal cells, and some of the cell bodies of amacrine cells." [BTO:0003176] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "INL" NARROW [] synonym: "inner nuclear layer" EXACT [] synonym: "retina inner nuclear layer" EXACT [] synonym: "stratum nucleare internum" EXACT [] synonym: "retinal inner nuclear layer" EXACT [] synonym: "intermediate cell layer" EXACT [ZFA:0000119] xref: FMA:58686 ! Inner nuclear layer of retina xref: MA:0001311 ! retina inner nuclear layer xref: XAO:0003221 ! retinal inner nuclear layer xref: ZFA:0000119 ! retinal inner nuclear layer xref: VHOG:0001167 ! retinal inner nuclear layer xref: NIF_GrossAnatomy:nlx_anat_1005031 ! Retina inner nuclear layer xref: BTO:0003176 ! inner nuclear layer xref: EMAPA:19155 ! inner nuclear layer is_a: UBERON:0001781 ! layer of retina relationship: part_of UBERON:0003902 ! retinal neural layer relationship: has_part CL:0000748 ! retinal bipolar neuron relationship: has_part CL:0000561 ! amacrine cell relationship: has_part CL:0000745 ! horizontal cell relationship: adjacent_to UBERON:0001795 ! inner plexiform layer of retina xref: SCTID:362520009 ! Entire inner nuclear layer of retina xref: ncithesaurus:Inner_Nuclear_Layer ! Inner Nuclear Layer xref: TAO:0000119 ! retinal inner nuclear layer property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001167", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229211 [Term] id: UBERON:0001792 ! ganglionic layer of retina name: ganglionic layer of retina def: "a layer of the retina that consists of retinal ganglion cells[WP]. innermost nuclear layer of the retina, which contains neurons that project axons through the optic nerve to the brain." [Wikipedia:Ganglion_cell_layer] comment: Check exact synonyms in ZFA / XAO subset: uberon_slim subset: vertebrate_core synonym: "RGC layer" EXACT [] synonym: "GCL layer" EXACT [] synonym: "ganglion cell layer" EXACT [FMA:58687, ZFA:0000024] synonym: "ganglionic cell layer of retina" EXACT [FMA:58687] synonym: "stratum ganglionicum (retina)" EXACT [FMA:58687] synonym: "retina ganglion cell layer" EXACT [] synonym: "retinal ganglion cell layer" EXACT [] synonym: "retinal ganglion layer" EXACT [MP:0008510] synonym: "retina ganglion layer" EXACT [] xref: FMA:58687 ! Ganglionic layer of retina xref: MA:0001310 ! retina ganglion cell layer xref: ZFA:0000024 ! retinal ganglion cell layer xref: ncithesaurus:Ganglion_Cell_Layer ! Ganglion Cell Layer xref: BTO:0003398 ! ganglion cell layer xref: XAO:0003223 ! retinal ganglion cell layer xref: VHOG:0001166 ! retinal ganglion cell layer xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray881.png/200px-Gray881.png xref: NIF_GrossAnatomy:nlx_anat_1005030 ! Retina ganglion cell layer is_a: UBERON:0001781 {source="FMA"} ! layer of retina relationship: part_of UBERON:0003902 {source="FMA"} ! retinal neural layer relationship: adjacent_to UBERON:0001793 ! nerve fiber layer of retina xref: SCTID:280670002 ! Entire ganglion cell layer of retina xref: TAO:0000024 ! retinal ganglion cell layer synonym: "stratum ganglionicum retinae" RELATED LATIN [Wikipedia:Ganglion_cell_layer] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001166", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001793 ! nerve fiber layer of retina name: nerve fiber layer of retina alt_id: UBERON:0005888 def: "Fiber layer adjacent the retinal ganglion cell layer which is comprised of their axons as they traverse to the optic nerve[ZFA]. The retinal nerve fiber layer (nerve fiber layer, stratum opticum, RNFL) is formed by the expansion of the fibers of the optic nerve; it is thickest near the porus opticus, gradually diminishing toward the ora serrata. As the nerve fibers pass through the lamina cribrosa sclerae they lose their medullary sheaths and are continued onward through the choroid and retina as simple axis-cylinders. When they reach the internal surface of the retina they radiate from their point of entrance over this surface grouped in bundles, and in many places arranged in plexuses. Most of the fibers are centripetal, and are the direct continuations of the axis-cylinder processes of the cells of the ganglionic layer, but a few of them are centrifugal and ramify in the inner plexiform and inner nuclear layers, where they end in enlarged extremities." [Wikipedia:Nervous_system_fiber_layer, ZFA:0001619] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "layer of nerve fibers of retina" EXACT [] synonym: "layer of nerve fibres of retina" EXACT [] synonym: "retina nerve fiber layer" EXACT [] synonym: "stratum neurofibrarum (retina)" EXACT [] synonym: "stratum opticum of retina" EXACT [] xref: FMA:58688 ! Nerve fiber layer of retina xref: VHOG:0001169 ! retina nerve fiber layer xref: MA:0001314 ! retina nerve fiber layer xref: EMAPA:18591 ! nerve fibre layer xref: ZFA:0001619 ! optic fiber layer xref: XAO:0003220 ! optic fiber layer is_a: UBERON:0001781 ! layer of retina relationship: overlaps UBERON:0000941 ! cranial nerve II relationship: part_of UBERON:0003902 ! retinal neural layer relationship: adjacent_to UBERON:0001794 ! inner limiting layer of retina synonym: "stratum neurofibrarum retinae" EXACT LATIN [FMA:TA, FMA:58688] xref: SCTID:280671003 ! Entire nerve fiber layer of retina xref: TAO:0002212 ! optic fiber layer synonym: "stratum neurofibrum retinae" RELATED LATIN [Wikipedia:Nerve_fiber_layer] synonym: "optic fiber layer" RELATED [VHOG:0001169] synonym: "optic fiber layers" RELATED PLURAL [TAO:0002212] property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001169", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001794 ! inner limiting layer of retina name: inner limiting layer of retina def: "the row of fused Muller cell processes and astrocytes that separates the retinal nerve fiber layer from the vitreous[MP]." [MP:0010235] comment: TODO - check frog/fish subset: vertebrate_core synonym: "inner limiting membrane of retina" EXACT [] synonym: "internal limiting lamina of retina" EXACT [] synonym: "internal limiting membrane of retina" EXACT [] synonym: "retina internal limiting lamina" EXACT [] synonym: "retina inner limiting membrane" EXACT [MP:0010235] synonym: "inner limiting membrane" EXACT [XAO:0003222] xref: FMA:58689 ! Inner limiting layer of retina xref: MA:0001313 ! retina internal limiting lamina xref: ZFA:0001029 ! inner limiting membrane xref: XAO:0003222 ! inner limiting membrane is_a: UBERON:0007619 {source="MA"} ! limiting membrane of retina relationship: overlaps CL:0000636 ! Muller cell relationship: adjacent_to UBERON:0001797 ! vitreous humor xref: ncithesaurus:Inner_Limiting_Membrane ! Inner Limiting Membrane xref: SCTID:280677004 ! Internal limiting membrane of retina xref: TAO:0001029 ! inner limiting membrane xref: UMLS:C1512783 property_value: external_definition "Membrane on the apical surface of the retina. The retinal vasculature becomes adhered to the apical surface of the ILM by 30dpf[ZFIN:ZDB-PUB-071023-7, ZFIN:ZDB-PUB-120529-3]." xsd:string {source="ZFIN:ZDB-PUB-071023-7, ZFIN:ZDB-PUB-120529-3"} [Term] id: UBERON:0001795 ! inner plexiform layer of retina name: inner plexiform layer of retina def: "The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells[GO]." [Wikipedia:Inner_plexiform_layer] comment: BTO misspelling? subset: vertebrate_core synonym: "IPL" NARROW [] synonym: "retina inner plexiform layer" EXACT [] synonym: "retinal inner plexiform layer" EXACT [] synonym: "stratum plexiforme internum" EXACT [FMA:58704] synonym: "stratum plexifome internum" RELATED [BTO:0003175] synonym: "inner plexiform layer" RELATED [BTO:0003175] xref: FMA:58704 ! Inner plexiform layer of retina xref: MA:0001312 ! retina inner plexiform layer xref: XAO:0003225 ! retinal inner plexiform layer xref: ZFA:0001329 ! retinal inner plexiform layer xref: BTO:0003175 ! inner plexiform layer xref: VHOG:0001168 ! retinal inner plexiform layer xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray881.png/200px-Gray881.png xref: NIF_GrossAnatomy:nlx_anat_1005032 ! Retina inner plexiform layer intersection_of: UBERON:0001781 ! layer of retina intersection_of: adjacent_to UBERON:0001791 ! INLr intersection_of: adjacent_to UBERON:0001792 ! RGC layer relationship: part_of UBERON:0003902 ! retinal neural layer relationship: overlaps CL:0000740 ! retinal ganglion cell relationship: overlaps CL:0000748 ! retinal bipolar neuron xref: ncithesaurus:Inner_Plexiform_Layer ! Inner Plexiform Layer xref: SCTID:280682006 ! Entire inner plexiform layer of retina xref: TAO:0001329 ! retinal inner plexiform layer synonym: "stratum plexiforme internum retinae" RELATED LATIN [Wikipedia:Inner_plexiform_layer] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png property_value: external_definition "The layer within the retina where the bipolar cells synapse with the dendrites of the ganglion cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001329", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0001168", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229221 [Term] id: UBERON:0008922 ! sublaminar layer S1 name: sublaminar layer S1 def: "A retinal neural layer that is immediately adjacent to the inner nuclear layer and comprises 20 percent of the inner plexiform layer of retina." [GOC:tfm] intersection_of: UBERON:0008921 ! substratum of layer of retina intersection_of: adjacent_to UBERON:0001791 ! inner nuclear layer of retina intersection_of: adjacent_to UBERON:0008923 ! sublaminar layer S2 relationship: part_of UBERON:0001795 ! inner plexiform layer of retina relationship: part_of UBERON:0008927 ! sublaminar layers S1 and S2 xref: CP:0000113 ! sublaminar layer S1 [Term] id: UBERON:0008923 ! sublaminar layer S2 name: sublaminar layer S2 def: "A retinal neural layer that is immediately adjacent to the S1 and S3 layers and comprises 20 percent of the inner plexiform layer of retina." [GOC:tfm] intersection_of: UBERON:0008921 ! substratum of layer of retina intersection_of: adjacent_to UBERON:0008922 ! sublaminar layer S1 intersection_of: adjacent_to UBERON:0008924 ! sublaminar layer S3 relationship: part_of UBERON:0001795 ! inner plexiform layer of retina relationship: part_of UBERON:0008927 ! sublaminar layers S1 and S2 relationship: part_of UBERON:0008928 ! sublaminar layers S2 and S3 xref: CP:0000114 ! sublaminar layer S2 [Term] id: UBERON:0008924 ! sublaminar layer S3 name: sublaminar layer S3 def: "A retinal neural layer that is immediately adjacent to the S2 and S4 layers and comprises 20 percent of the inner plexiform layer of retina." [GOC:tfm] intersection_of: UBERON:0008921 ! substratum of layer of retina intersection_of: adjacent_to UBERON:0008923 ! sublaminar layer S2 intersection_of: adjacent_to UBERON:0008925 ! sublaminar layer S4 relationship: part_of UBERON:0001795 ! inner plexiform layer of retina relationship: part_of UBERON:0008928 ! sublaminar layers S2 and S3 xref: CP:0000115 ! sublaminar layer S3 [Term] id: UBERON:0008925 ! sublaminar layer S4 name: sublaminar layer S4 def: "A retinal neural layer that is immediately adjacent to the S3 and S5 layer and comprises 20 percent of the inner plexiform layer of retina." [GOC:tfm] intersection_of: UBERON:0008921 ! substratum of layer of retina intersection_of: adjacent_to UBERON:0008924 ! sublaminar layer S3 intersection_of: adjacent_to UBERON:0008926 ! sublaminar layer S5 relationship: part_of UBERON:0001795 ! inner plexiform layer of retina relationship: part_of UBERON:0008929 ! sublaminar layers S4 and S5 xref: CP:0000116 ! sublaminar layer S4 [Term] id: UBERON:0008926 ! sublaminar layer S5 name: sublaminar layer S5 def: "A retinal neural layer that is immediately adjacent to the retinal ganglion cell layer and comprises 20 percent of the ganglion plexiform layer of retina." [GOC:tfm] intersection_of: UBERON:0008921 ! substratum of layer of retina intersection_of: adjacent_to UBERON:0008925 ! sublaminar layer S4 intersection_of: adjacent_to UBERON:0001792 ! ganglionic layer of retina relationship: part_of UBERON:0001795 ! inner plexiform layer of retina relationship: part_of UBERON:0008929 ! sublaminar layers S4 and S5 xref: CP:0000117 ! sublaminar layer S5 [Term] id: UBERON:0008927 ! sublaminar layers S1 or S2 name: sublaminar layers S1 or S2 def: "One of sublaminar layers S1 or S2." [GOC:tfm] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008922 ! sublaminar layer S1 union_of: UBERON:0008923 ! sublaminar layer S2 relationship: part_of UBERON:0001795 ! inner plexiform layer of retina xref: CP:0000118 ! sublaminar layers S1 or S2 [Term] id: UBERON:0008928 ! sublaminar layers S2 or S3 name: sublaminar layers S2 or S3 def: "One of sublaminar layers S2 or S3." [GOC:tfm] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008923 ! sublaminar layer S2 union_of: UBERON:0008924 ! sublaminar layer S3 relationship: part_of UBERON:0001795 ! inner plexiform layer of retina xref: CP:0000119 ! sublaminar layers S2 or S3 [Term] id: UBERON:0008929 ! sublaminar layers S4 or S5 name: sublaminar layers S4 or S5 def: "One of sublaminar layers S4 or S5." [GOC:tfm] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008925 ! sublaminar layer S4 union_of: UBERON:0008926 ! sublaminar layer S5 relationship: part_of UBERON:0001795 ! inner plexiform layer of retina xref: CP:0000120 [Term] id: UBERON:0009731 name: sublaminar layers S3 or S4 def: "One of sublaminar layers S3 or S4." [GOC:plr] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008924 ! sublaminar layer S3 union_of: UBERON:0008925 ! sublaminar layer S4 xref: CP:0001040 ! sublaminar layers S3 or S4 [Term] id: UBERON:0009732 name: sublaminar layers S1 or S2 or S5 def: "One of sublaminar layers S1, S2, or S5." [GOC:plr] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008922 ! sublaminar layer S1 union_of: UBERON:0008923 ! sublaminar layer S2 union_of: UBERON:0008926 ! sublaminar layer S5 xref: CP:0001041 ! sublaminar layers S1 or S2 or S5 [Term] id: UBERON:0009733 name: sublaminar layers S1 or S2 or S3 def: "One of sublaminar layers S1, S2, or S3." [GOC:plr] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008922 ! sublaminar layer S1 union_of: UBERON:0008923 ! sublaminar layer S2 union_of: UBERON:0008924 ! sublaminar layer S3 xref: CP:0001042 ! sublaminar layers S1 or S2 or S3 [Term] id: UBERON:0009734 name: sublaminar layers S2 or S3 or S4 def: "One of sublaminar layers S2, S3, or S4." [GOC:plr] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008923 ! sublaminar layer S2 union_of: UBERON:0008924 ! sublaminar layer S3 union_of: UBERON:0008925 ! sublaminar layer S4 xref: CP:0001043 ! sublaminar layers S2 or S3 or S4 [Term] id: UBERON:0009735 name: sublaminar layers S1 or S3 or S4 def: "One of sublaminar layers S1, S3, or S4." [GOC:plr] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008922 ! sublaminar layer S1 union_of: UBERON:0008924 ! sublaminar layer S3 union_of: UBERON:0008925 ! sublaminar layer S4 xref: CP:0001044 ! sublaminar layers S1 or S3 or S4 [Term] id: UBERON:0009736 name: sublaminar layers S3 or S4 or S5 def: "One of sublaminar layers S3, S4, or S5." [GOC:plr] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008924 ! sublaminar layer S3 union_of: UBERON:0008925 ! sublaminar layer S4 union_of: UBERON:0008926 ! sublaminar layer S5 xref: CP:0001045 ! sublaminar layers S3 or S4 or S5 [Term] id: UBERON:0009737 name: sublaminar layers S1 or S2 or S3 or S4 def: "One of sublaminar layers S1, S2, S3, or S4." [GOC:plr] is_a: UBERON:0008921 ! substratum of layer of retina union_of: UBERON:0008922 ! sublaminar layer S1 union_of: UBERON:0008923 ! sublaminar layer S2 union_of: UBERON:0008924 ! sublaminar layer S3 union_of: UBERON:0008925 ! sublaminar layer S4 xref: CP:0001046 ! sublaminar layers S1 or S2 or S3 or S4 [Term] id: UBERON:0009738 name: border of sublaminar layers S1 and S2 def: "The region extending out from the boundary between layers S1 and S2." [GOC:plr, UBERON:cjm] intersection_of: UBERON:0009740 ! border between sublaminar layers intersection_of: overlaps UBERON:0008922 ! sublaminar layer S1 intersection_of: overlaps UBERON:0008923 ! sublaminar layer S2 relationship: part_of UBERON:0008927 ! sublaminar layers S1 and S2 xref: CP:0001038 ! intersection of sublaminar layers S1 and S2 [Term] id: UBERON:0009739 name: border of sublaminar layers S3 and S4 def: "The region extending out from the boundary between sublaminar layers S3 and S4." [GOC:plr, UBERON:cjm] intersection_of: UBERON:0009740 ! border between sublaminar layers intersection_of: overlaps UBERON:0008924 ! sublaminar layer S3 intersection_of: overlaps UBERON:0008925 ! sublaminar layer S4 relationship: part_of UBERON:0009731 ! sublaminar layers S3 and S4 xref: CP:0001039 ! intersection of sublaminar layers S3 and S4 [Term] id: UBERON:0009851 name: border of sublaminar layers S4 and S5 def: "The intersection of sublaminar layers S4 and S5." [GOC:tfm] intersection_of: UBERON:0009740 ! border between sublaminar layers intersection_of: overlaps UBERON:0008926 ! sublaminar layer S5 intersection_of: overlaps UBERON:0008925 ! sublaminar layer S4 relationship: part_of UBERON:0008929 ! sublaminar layers S4 or S5 [Term] id: UBERON:0009852 name: border of sublaminar layers S2 and S3 def: "The intersection of sublaminar layers S2 and S3." [GOC:tfm] intersection_of: UBERON:0009740 ! border between sublaminar layers intersection_of: overlaps UBERON:0008923 ! sublaminar layer S2 intersection_of: overlaps UBERON:0008924 ! sublaminar layer S3 relationship: part_of UBERON:0008928 ! sublaminar layers S2 or S3 [Term] id: UBERON:0009740 ! border between sublaminar layers name: border between sublaminar layers def: "A region of the retina corresponding to a portion of two adjacent substratum layers." [UBERON:cjm] is_a: UBERON:0004923 ! organ component layer relationship: overlaps UBERON:0008921 ! substratum of layer of retina relationship: part_of UBERON:0000966 ! retina [Term] id: UBERON:0006312 ! ocular refractive media name: ocular refractive media xref: MA:0001911 ! ocular refractive media is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0001796 name: aqueous humor of eyeball def: "Body substance in liquid state contained in the anterior and posterior chambers of the eyeball[FMA]. The aqueous humour is a thick watery substance filling the space between the lens and the cornea[WP]." [Wikipedia:Aqueous_humor, FMA:58819] comment: Note that FMA says A+P chambers, and MA states A chamber. ZFA states A chamber and tha it is produced primarily by dorsal ciliary epithelial cells.To be investigated across taxa. subset: uberon_slim subset: vertebrate_core synonym: "aqueous humor" EXACT [] synonym: "aqueous humour" EXACT [] synonym: "aqueous humour" EXACT [EHDAA2:0000139] xref: EHDAA:10196 ! aqueous humour xref: ENVO:02000024 xref: FMA:58819 ! Aqueous humor of eyeball xref: GAID:890 ! aqueous humor xref: VHOG:0000548 ! aqueous humour xref: MA:0001236 ! aqueous humour xref: OpenCyc:Mx4rvdGd-5wpEbGdrcN5Y29ycA xref: ncithesaurus:Aqueous_Humor ! Aqueous Humor xref: OpenCyc:Mx4rvdGd-5wpEbGdrcN5Y29ycA ! aqueous humor xref: EHDAA2:0000139 ! aqueous humour xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: EMAPA:18232 ! aqueous humour xref: MESH:A09.371.060.067.070 ! aqueous humor xref: ZFA:0005564 ! aqueous humor is_a: UBERON:0006312 ! ocular refractive media relationship: part_of UBERON:0001766 {source="VHOG", notes="located_in in EHDAA2"} ! anterior chamber of eyeball synonym: "humor aquosus" EXACT LATIN [FMA:TA, FMA:58819] xref: SCTID:280587006 ! Entire aqueous humor property_value: external_definition "The fluid produced by the ciliary process in the eye and occupying the anterior and posterior chambers. It provides nourishment for the lens and cornea and maintains the ocular pressure, and hence the optical integrity of the eyeball. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000548", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/aqueous+humour", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000548", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.424 and p.426 and p.429 and Figure 12-24", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0003662 [Term] id: UBERON:0001797 ! vitreous humor name: vitreous humor def: "Body substance of semisolid state which constitutes the vitreous body of the eye.[FMA]" [Wikipedia:Vitreous_humour, FMA:FMA] comment: Note that FMA distinguishes between a portion and the whole portion. We equate with whole portion here, but this is arbitrary subset: uberon_slim subset: vertebrate_core synonym: "humor vitreous" EXACT [] synonym: "vitreous humour" RELATED [] synonym: "whole portion of vitreous humor" EXACT [FMA:58822] synonym: "portion of vitreous humor" BROAD [FMA:67388] synonym: "humoral fluid" RELATED [BTO:0001451] synonym: "ocular fluid" RELATED [BTO:0001451] synonym: "vitreous fluid" RELATED [BTO:0001451] synonym: "vitreous" EXACT [ZFA:0005561] xref: ENVO:02000032 xref: FMA:58822 ! Whole portion of vitreous humor xref: MA:0001286 ! vitreous humor xref: OpenCyc:Mx4rv7ZIfZwpEbGdrcN5Y29ycA xref: ncithesaurus:Vitreous_Humor ! Vitreous Humor xref: BTO:0001451 ! vitreous humor xref: OpenCyc:Mx4rv7ZIfZwpEbGdrcN5Y29ycA ! vitreous humor xref: VHOG:0000795 ! vitreous humour xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: EMAPA:17837 ! vitreous humour xref: EV:0100344 ! vitreous humor xref: ZFA:0005561 ! vitreous is_a: UBERON:0006312 ! ocular refractive media relationship: part_of UBERON:0001798 ! vitreous body relationship: located_in UBERON:0005606 ! hyaloid cavity synonym: "humor vitreus" EXACT LATIN [FMA:TA, FMA:58822] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg xref: UMLS:C0229096 [Term] id: UBERON:0001798 name: vitreous body def: "Mucoid tissue in the vitreous chamber of the eyeball. Examples: There are only two instances, right and left vitreous bodies.[FMA]" [FMA:58827, FMA:FMA] comment: Note - in many AOs these are exact synonyms, but FMA has a part of link between portion of vitreous humor and this subset: uberon_slim xref: FMA:58827 ! Vitreous body xref: GAID:919 ! vitreous body xref: MA:0002462 ! vitreous body xref: ncithesaurus:Vitreous_Body ! Vitreous Body xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: MESH:A09.371.943 ! vitreous body is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0001799 ! vitreous chamber of eyeball xref: SCTID:181170006 ! Entire vitreous body xref: UMLS:C0042905 [Term] id: UBERON:0001799 name: vitreous chamber of eyeball def: "The posterior chamber is a narrow chink behind the peripheral part of the iris of the human eye, and in front of the suspensory ligament of the lens and the ciliary processes the Posterior Chamber consists of small space directly posterior of the Iris but anterior to the lens. [WP,unvetted]." [Wikipedia:Vitreous_chamber] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "camera postrema" EXACT [] synonym: "camera vitrea" EXACT [] synonym: "camera vitrea bulbi" EXACT [] synonym: "postremal chamber" EXACT [] synonym: "postremal chamber of eyeball" EXACT [] synonym: "vitreous chamber" EXACT [] xref: FMA:58848 ! Vitreous chamber of eyeball xref: MA:0002461 ! vitreous chamber xref: ncithesaurus:Vitreous_Chamber ! Vitreous Chamber xref: BTO:0002087 ! vitreous chamber of the eye is_a: UBERON:0006311 ! chamber of eyeball relationship: part_of UBERON:0001802 ! posterior segment of eyeball synonym: "camera postrema bulbi oculi" EXACT LATIN [FMA:TA, FMA:58848] xref: UMLS:C0229095 [Term] id: UBERON:0005746 name: primary vitreous humour def: "embryonic fibrovascular mesodermal tissue located between the optic cup and lens vesicle that normally regresses during the development of the vitreous body[MP]" [MP:0010711] comment: Acellular in EHDAA2, MP defs says tissue synonym: "primary vitreous" EXACT [MP:0010711] xref: EHDAA2:0001502 ! primary vitreous humour xref: EHDAA:5707 ! primary vitreous humour xref: SCTID:343518007 ! Entire primary vitreous is_a: UBERON:0000476 {source="EHDAA2", inconsistent_with="MP-def"} ! acellular anatomical structure relationship: develops_from UBERON:0003902 {source="EHDAA2"} ! retinal neural layer relationship: located_in UBERON:0005606 {source="EHDAA2"} ! hyaloid cavity relationship: part_of UBERON:0008816 {source="cjm"} ! embryonic head [Term] id: UBERON:0001800 name: sensory ganglion def: "the clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells." [MP:0000960] comment: This class was created automatically from a combination of ontologies synonym: "ganglion sensorium" EXACT [] xref: FMA:5885 ! Sensory ganglion xref: MA:0002566 ! sensory ganglion xref: AEO:0001000 ! sensory ganglion xref: ncithesaurus:Sensory_Ganglion ! Sensory Ganglion xref: MESH:A08.340.390 ! sensory ganglia is_a: UBERON:0000045 ! ganglion xref: UMLS:C0206429 [Term] id: UBERON:0001801 name: anterior segment of eyeball def: "The anterior segment is the front third of the eye that includes the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens. Within the anterior segment are two fluid-filled spaces: the anterior chamber between the posterior surface of the cornea (i.e. the corneal endothelium) and the iris; the posterior chamber between the iris and the front face of the vitreous. Aqueous humor fills these spaces within the anterior segment and provides nutrients to the surrounding structures." [Wikipedia:Anterior_segment_of_eyeball] subset: vertebrate_core synonym: "anterior segment of eye" EXACT [] synonym: "anterior segment of the eye" EXACT [] synonym: "eye anterior segment" EXACT [] synonym: "segmentum anterius (bulbus oculi)" EXACT [] xref: FMA:58865 ! Anterior segment of eyeball xref: MA:0002484 ! eye anterior segment xref: MESH:A09.371.060 ! anterior eye segment xref: ZFA:0005566 ! anterior segment eye is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye relationship: spatially_disjoint_from UBERON:0001802 ! posterior segment of eyeball xref: ncithesaurus:Anterior_Eye_Segment ! Anterior Eye Segment xref: SCTID:280658001 ! Entire anterior segment of eyeball synonym: "segmentum anterius bulbi oculi" RELATED LATIN [Wikipedia:Anterior_segment_of_eyeball] xref: http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png xref: UMLS:C0003153 [Term] id: UBERON:0001802 name: posterior segment of eyeball def: "The posterior segment is the back two-thirds of the eye that includes the anterior hyaloid membrane and all structures behind it: the vitreous humor, retina, choroid, and optic nerve. On the anterior side of the lens is the aqueous humour which is bounded on all sides by the lens, ciliary body, suspensory ligaments, and by the cornea. It lets light through without refraction, helps maintain the shape of the eye and suspends the delicate lens. In some animals, the retina contains a reflective layer (the tapetum lucidum) which increases the amount of light each photosensitive cell perceives, allowing the animal to see better under low light conditions." [Wikipedia:Posterior_segment_of_eyeball] subset: vertebrate_core synonym: "eye posterior segment" EXACT [] synonym: "posterior segment of eye" EXACT [] synonym: "posterior segment of the eye" EXACT [] synonym: "segmentum posterius (bulbus oculi)" EXACT [] xref: FMA:58868 ! Posterior segment of eyeball xref: MA:0002485 ! eye posterior segment xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: ZFA:0005567 ! posterior segment eye is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye xref: ncithesaurus:Posterior_Eye_Segment ! Posterior Eye Segment xref: SCTID:280659009 ! Entire posterior segment of eyeball synonym: "segmentum posterius bulbi oculi" RELATED LATIN [Wikipedia:Posterior_segment_of_eyeball] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg xref: UMLS:C0278450 [Term] id: UBERON:0001803 name: epithelium of lens def: "The cells of the lens epithelium regulate most of the homeostatic functions of the lens.[6] As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions." [Wikipedia:Lens_(anatomy)#Lens_Epithelium] comment: Usage notes: this class is the superclass of the anterior epithelium and equatorial epithlium, although the term 'lens epithelium' may refer specifically to the former subset: vertebrate_core synonym: "lens epithelium" EXACT [] synonym: "epithelial tissue of eye lens" EXACT [OBOL:automatic] synonym: "epithelial tissue of lens" EXACT [OBOL:automatic] synonym: "epithelium of eye lens" EXACT [OBOL:automatic] synonym: "eye lens epithelial tissue" EXACT [OBOL:automatic] synonym: "eye lens epithelium" EXACT [OBOL:automatic] synonym: "lens epithelial tissue" EXACT [OBOL:automatic] xref: FMA:58871 ! Epithelium of lens xref: MA:0001301 ! lens epithelium xref: TAO:0001326 ! lens epithelium xref: ZFA:0001326 ! lens epithelium xref: BTO:0001873 ! lens epithelium is_a: UBERON:0000484 ! simple cuboidal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000965 ! lens relationship: part_of UBERON:0000965 ! lens synonym: "epithelium lentis" EXACT LATIN [FMA:TA, FMA:58871] xref: SCTID:362523006 ! Entire epithelium of lens xref: XAO:0004094 ! lens epithelium [Term] id: UBERON:0005614 name: lens anterior epithelium comment: Cells of the subcapsular epithelium (or anterior lens cells) are mitotically active. In adult individuals they only cover the anterior "hemisphere" of the lens. As they divide, cells gradually move towards the equator of the lens where they tranform into lens fibres. The apical part of the gradually elongating cell extends between the subcapsular epithelium and adjacent lens fibres towards the anterior pole of the lens. The basal part extends towards the posterior pole. The nucleus remains close to the equatorial plane of the lens - http://www.lab.anhb.uwa.edu.au/mb140/corepages/eye/eye.htm synonym: "lens epithelium" BROAD [] synonym: "anterior surface of lens" RELATED [FMA:58889] synonym: "subcapsular lens epithelium" EXACT [FMA:70612] synonym: "lens subcapsular epithelium" EXACT [http://www.lab.anhb.uwa.edu.au/mb140/corepages/eye/eye.htm] synonym: "anterior epithelium of lens vesicle" RELATED [EMAPA:17304] xref: EMAPA:17304 ! anterior epithelium of lens vesicle xref: MA:0001302 ! lens anterior epithelium xref: RETIRED_EHDAA2:0000976 ! lens anterior epithelium xref: EMAPA:17839 ! anterior epithelium of lens xref: VHOG:0001425 ! lens anterior epithelium xref: EHDAA:9059 ! anterior epithelium of lens is_a: UBERON:0001803 ! epithelium of lens relationship: develops_from UBERON:0000924 {source="FMA-inferred"} ! ectoderm xref: EHDAA2:0000984 ! lens anterior epithelium xref: FMA:70612 ! subcapsular lens epithelium xref: ncithesaurus:Subcapsular_Epithelium_of_the_Lens ! subcapsular epithelium of the lens xref: SCTID:362521008 ! Entire anterior surface of lens xref: UMLS:C1182652 [Term] id: UBERON:0005615 name: lens equatorial epithelium xref: MA:0001303 ! lens equatorial epithelium xref: RETIRED_EHDAA2:0000978 ! lens equatorial epithelium xref: EMAPA:17840 ! equatorial epithelium of lens xref: EHDAA:9063 ! equatorial epithelium of lens is_a: UBERON:0001803 ! epithelium of lens xref: VHOG:0001459 ! lens equatorial epithelium [Term] id: UBERON:0005656 name: lens vesicle epithelium xref: EHDAA2:0000987 ! lens vesicle epithelium xref: EMAPA:17165 ! epithelium of lens vesicle xref: VHOG:0000532 ! lens vesicle epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005426 ! lens vesicle def: "An epithelium that is part of a lens vesicle." [OBOL:automatic] [Term] id: UBERON:0005714 name: obsolete lens vesicle capsule consider: RETIRED_EHDAA2:0000985 ! lens vesicle capsule consider: EHDAA:4739 ! capsule is_obsolete: true consider: UBERON:0001804 ! capsule of lens [Term] id: UBERON:0001804 ! capsule of lens name: capsule of lens def: "a smooth, transparent basement membrane that completely surrounds the lens. It is synthesized by the lens epithelium and its main components are Type IV collagen and sulfated glycosaminoglycans (GAGs)." [Wikipedia:Capsule_of_lens, Wikipedia:Lens_(anatomy)#Lens_capsule] synonym: "lens capsule" EXACT [] synonym: "capsula lentis" EXACT LATIN [] subset: uberon_slim subset: vertebrate_core xref: FMA:58881 ! Capsule of lens xref: VHOG:0000550 ! lens capsule xref: MA:0001300 ! lens capsule xref: ncithesaurus:Lens_Capsule ! Lens Capsule xref: EHDAA2:0000977 ! lens capsule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray883.png/200px-Gray883.png xref: EMAPA:18237 ! capsule xref: ZFA:0005574 ! lens capsule is_a: UBERON:0003893 ! capsule is_a: UBERON:0005769 {source="Wikipedia"} ! basement membrane intersection_of: UBERON:0003893 ! capsule intersection_of: surrounds UBERON:0000965 ! lens relationship: surrounds UBERON:0000965 ! lens relationship: develops_from UBERON:0001803 {source="Wikipedia"} ! epithelium of lens relationship: develops_from UBERON:0005614 {source="EHDAA2"} ! lens anterior epithelium xref: SCTID:244500004 ! Entire lens capsule xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png property_value: external_definition "The transparent membrane which surrounds the lens of the eye. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000550", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000550", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN Jr\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.424 and p.426 and p.429 and Figure 12-24", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229232 [Term] id: UBERON:0002444 name: lens fiber def: "The lens fibers form the bulk of the lens. They are long, thin, transparent cells, with diameters typically between 4-7 micrometres and lengths of up to 12 mm long." [Wikipedia:Lens_(anatomy)#Lens_fibers] comment: TODO - check plural vs singular. in FMA lens fiber is a cell - FMA:70950 Lens cell. Other ontologies don't appear to commit one way or another. synonym: "lens fibers" EXACT [] synonym: "lens fibers set" EXACT [] synonym: "lens fibres" EXACT [] xref: BTO:0000724 xref: EHDAA:4745 ! lens fibres xref: EHDAA:9065 ! lens fibres xref: FMA:76827 ! Set of lens fibers xref: VHOG:0000444 ! lens fibres xref: MA:0001304 ! lens fiber xref: ncithesaurus:Lens_Fiber ! Lens Fiber xref: RETIRED_EHDAA2:0000979 ! lens fibres xref: EMAPA:17841 ! lens fibre is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000965 ! lens synonym: "fibrae lentis" EXACT LATIN [FMA:TA, FMA:76827] xref: XAO:0004096 ! lens fiber cell mass synonym: "set of lens fibers" RELATED [FMA:76827] property_value: external_definition "Fibres resembling a ribbon and arranged in very thin plates in the lens. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000444", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the line, or Y, or star sutures common to mammalian lenses, including those of primates. In the case of line or Y sutures, the overlapping of lens fibers in each successive shell is coincident and results in the formation of four or six three-dimensional suture planes that extend from the lens nucleus to the periphery.[well established][VHOG]" xsd:string {external_class="VHOG:0000444", ontology="VHOG", source="DOI:10.1167/iovs.03-0466 Sivak JG\, Through the lens clearly: phylogeny and development\, The Proctor lecture. Investigative ophthalmology and visual science (2004)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229224 [Term] id: UBERON:0007622 name: pecten oculi def: "a comb-like structure of blood vessels belonging to the choroid in the eye of a bird or reptile. It is non-sensory and is a pigmented structure that projects into the vitreous body from the point where the optic nerve enters the eyeball. The pecten is believed to both nourish the retina and control the pH of the vitreous body." [Wikipedia:Pecten_oculi] is_a: UBERON:0002049 ! vasculature relationship: part_of UBERON:0001776 ! optic choroid relationship: only_in_taxon NCBITaxon:8457 ! Sauropsida [Term] id: UBERON:0007623 name: comb and wattle def: "A wattle is a fleshy dewlap or caruncle hanging from various parts of the head or neck in several groups of birds, goats and other animals. In some birds the caruncle is erectile tissue." [Wikipedia:Wattle_(anatomy)] synonym: "wattle" RELATED [GAID:1207] synonym: "wattles and comb" RELATED [GAID:1207] xref: MESH:A13.242 xref: GAID:1207 ! comb and wattle xref: SCTID:37118002 ! Wattle structure is_a: UBERON:0000021 ! cutaneous appendage relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0012176 ! comb name: comb def: "a vascular, red cutaneous structure attached in a sagittal plane to the dorsum of the skull of domestic fowl. It consists of a base attached to the skull, a central mass called the body, a backward projecting blade and upward projecting points" [http://medical-dictionary.thefreedictionary.com/pea+comb] is_a: UBERON:0000021 ! cutaneous appendage relationship: only_in_taxon NCBITaxon:8782 ! Aves xref: SCTID:3643003 ! Comb structure [Term] id: UBERON:1000003 name: dewlap def: "A longitudinal flap of skin that hangs beneath the lower jaw or neck." [Wikipedia:Dewlap] comment: Compare with: comb and wattle subset: phenotype_rcn is_a: UBERON:0000014 ! zone of skin relationship: part_of UBERON:0001456 ! face xref: SCTID:13622004 ! Dewlap structure [Term] id: UBERON:0001805 name: autonomic ganglion def: "ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion." [Wikipedia:Autonomic_ganglion] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "autonomic nervous system ganglion" EXACT [OBOL:automatic] synonym: "ganglion of autonomic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of visceral nervous system" EXACT [OBOL:automatic] synonym: "visceral nervous system ganglion" EXACT [OBOL:automatic] xref: FMA:5889 ! Autonomic ganglion xref: MA:0000220 ! autonomic ganglion xref: ncithesaurus:Autonomic_Ganglion ! Autonomic Ganglion xref: EMAPA:17157 ! ganglion of sympathetic (also: UBERON:0001806 'sympathetic ganglion') xref: EMAPA:18221 ! ganglion of autonomic xref: AEO:0001001 ! autonomic ganglion is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0002410 ! autonomic nervous system synonym: "ganglion autonomicum" RELATED LATIN [Wikipedia:Autonomic_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png xref: UMLS:C0017068 [Term] id: UBERON:0001806 name: sympathetic ganglion def: "Sympathetic ganglia are the ganglia of the sympathetic nervous system. They deliver information to the body about stress and impending danger, and are responsible for the familiar fight-or-flight response. They contain approximately 20000–30000 nerve cell bodies and are located close to and on either side of the spinal cord in long chains. [WP,unvetted]." [Wikipedia:Sympathetic_ganglion] subset: uberon_slim synonym: "ganglion sympatheticum" EXACT [] synonym: "ganglion of sympathetic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of sympathetic part of autonomic division of nervous system" EXACT [OBOL:automatic] synonym: "sympathetic nervous system ganglion" EXACT [OBOL:automatic] synonym: "sympathetic part of autonomic division of nervous system ganglion" EXACT [OBOL:automatic] synonym: "ganglion sympathicum" RELATED [BTO:0001333] xref: BTO:0001333 xref: FMA:5890 ! Sympathetic ganglion xref: MA:0000226 ! sympathetic ganglion xref: ncithesaurus:Sympathetic_Ganglion ! Sympathetic Ganglion xref: EHDAA2:0001969 ! sympathetic ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f7/Gray839.png/200px-Gray839.png xref: EMAPA:17157 ! ganglion of sympathetic (also: UBERON:0001805 'autonomic ganglion') is_a: UBERON:0001805 ! autonomic ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0000013 ! sympathetic nervous system relationship: develops_from UBERON:0002342 {source="ISBN10:0073040584"} ! neural crest xref: AAO:0010773 ! sympathetic ganglion xref: SCTID:362485003 ! Entire sympathetic ganglion synonym: "ganglion sympathicum" RELATED LATIN [Wikipedia:Sympathetic_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png xref: UMLS:C0017071 [Term] id: UBERON:0001807 name: paravertebral ganglion def: "Trunk ganglion which is part of a bilaterally paired set of sympathetic ganglia located anterior and lateral to the spinal cord." [Wikipedia:Paravertebral_ganglion, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "ganglion of sympathetic trunk" EXACT [] synonym: "ganglion trunci sympathetici" EXACT [] synonym: "sympathetic chain ganglion" EXACT [] xref: FMA:5891 ! Paravertebral ganglion xref: TAO:0001556 ! sympathetic chain ganglion xref: ZFA:0001556 ! sympathetic chain ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Gray847.png/200px-Gray847.png is_a: UBERON:0007134 {source="ZFA"} ! trunk ganglion relationship: part_of UBERON:0000013 {source="ZFA"} ! sympathetic nervous system synonym: "ganglion trunci sympathici" EXACT LATIN [FMA:TA, FMA:5891] [Term] id: UBERON:0001808 name: parasympathetic ganglion def: "Parasympathetic ganglia are the autonomic ganglia of the parasympathetic nervous system. Most are small terminal ganglia or intramural ganglia, so named because they lie near or within (respectively) the organs they innervate. The exceptions are the four paired parasympathetic ganglia of the head and neck. [WP,unvetted]." [Wikipedia:Parasympathetic_ganglion] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "ganglion parasympathicum" RELATED [BTO:0001256] xref: BTO:0001256 xref: FMA:5894 ! Parasympathetic ganglion xref: MA:0002469 ! parasympathetic ganglion xref: ncithesaurus:Parasympathetic_Ganglion ! Parasympathetic Ganglion xref: NIF_GrossAnatomy:nlx_anat_100303 ! Parasympathetic ganglion xref: EHDAA2:0001400 ! parasympathetic ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f7/Gray839.png/200px-Gray839.png intersection_of: UBERON:0001805 ! autonomic ganglion intersection_of: part_of UBERON:0000011 ! parasympathetic nervous system relationship: develops_from UBERON:0002342 {source="ISBN10:0073040584"} ! neural crest xref: SCTID:279284004 ! Entire parasympathetic ganglion synonym: "ganglion parasympathicum" RELATED LATIN [Wikipedia:Parasympathetic_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png xref: UMLS:C0017069 [Term] id: UBERON:0001809 name: enteric ganglion def: "." [Wikipedia:Enteric_ganglia] synonym: "intramural ganglion" EXACT [FMA:5896] xref: FMA:5896 ! Enteric ganglion xref: MA:0001144 ! enteric ganglion xref: ncithesaurus:Enteric_Ganglion ! Enteric Ganglion is_a: UBERON:0001808 {source="FMA"} ! parasympathetic ganglion intersection_of: UBERON:0001808 ! parasympathetic ganglion intersection_of: part_of UBERON:0002005 ! enteric nervous system xref: UMLS:C0501399 [Term] id: UBERON:0001810 name: nerve plexus def: "Anatomical junction where subdivisions of two or more neural trees interconnect with one another to form a network through which nerve fibers of the constituent nerve trees become regrouped; together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. Examples: cervical nerve plexus, brachial nerve plexus, sacral nerve plexus[FMA]." [Wikipedia:Nervous_system_plexus, FMA:5901] comment: in FMA this is a subtype of junction rather than tissue subset: uberon_slim xref: BTO:0000205 xref: EHDAA:3780 ! nerve plexus xref: FMA:5901 ! Nerve plexus xref: MA:0002407 ! nerve plexus xref: ncithesaurus:Nerve_Plexus ! Nerve Plexus xref: EHDAA2:0003138 ! nerve plexus xref: AEO:0000138 ! nerve plexus is_a: UBERON:0003714 ! neural tissue relationship: part_of UBERON:0001016 ! nervous system relationship: has_part CL:0000526 {source="AEO"} ! afferent neuron relationship: has_part CL:0000527 {source="AEO"} ! efferent neuron xref: SCTID:122455009 ! Structure of nerve plexus xref: UMLS:C0501403 [Term] id: UBERON:0005906 name: serous sac def: "Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]" [FMA:9689] comment: See notes for serous membrane xref: FMA:9689 ! serous sac xref: SCTID:362890006 ! Entire serous sac is_a: UBERON:0000062 ! organ relationship: has_part UBERON:0000042 ! serous membrane relationship: has_part UBERON:0002553 ! anatomical cavity [Term] id: UBERON:0005908 ! conjunctival sac name: conjunctival sac def: "Serous sac, which has as parts the conjunctiva and the cavity of conjunctiva. Examples: There are only two conjunctival sacs, the right and the left.[FMA]" [FMA:20291] xref: FMA:20291 ! conjunctival sac xref: EMAPA:18233 ! conjunctival sac is_a: UBERON:0005906 {source="FMA"} ! serous sac relationship: part_of UBERON:0000019 {source="FMA"} ! camera-type eye relationship: part_of UBERON:0001801 {source="MA"} ! anterior segment of eyeball xref: SCTID:362531001 ! Entire conjunctival sac [Term] id: UBERON:0001811 ! conjunctiva name: conjunctiva def: "The conjunctiva is a clear mucous membrane consisting of cells and underlying basement membrane that covers the sclera (white part of the eye) and lines the inside of the eyelids. It is made of epithelial tissue. [WP,unvetted]." [Wikipedia:Conjunctiva] subset: uberon_slim synonym: "wall of conjunctival sac" EXACT [] xref: EFO:0000374 ! conjunctiva xref: FMA:59011 ! Conjunctiva xref: GAID:898 ! conjunctiva xref: MA:0000265 ! conjunctiva xref: ncithesaurus:Conjunctiva xref: XAO:0000182 ! conjunctiva xref: BTO:0003415 ! conjunctiva xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/55/Gray883.png/200px-Gray883.png xref: MESH:A09.371.192 ! conjunctiva xref: EV:0100340 ! conjunctiva is_a: UBERON:0000060 {source="FMA"} ! anatomical wall relationship: part_of UBERON:0005908 {source="cjm"} ! conjunctival sac relationship: part_of UBERON:0010409 {source="MA"} ! eye surface relationship: adjacent_to UBERON:0001711 ! eyelid relationship: adjacent_to UBERON:0001773 ! sclera xref: AAO:0010343 ! conjunctiva xref: SCTID:181161008 ! Entire conjunctiva xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png property_value: has_relational_adjective "conjunctival" xsd:string xref: UMLS:C0009758 [Term] id: UBERON:0010305 name: region of conjunctiva def: "The conjunctiva is divided into 3 parts." [Wikipedia:Conjunctiva#Gross_anatomy] synonym: "conjunctiva subdivision" EXACT [FMA:59023] subset: grouping_class xref: FMA:59023 ! region of conjunctiva intersection_of: UBERON:0000064 ! organ part intersection_of: part_of UBERON:0001811 ! conjunctiva [Term] id: UBERON:0010306 name: bulbar conjunctiva comment: covers the eyeball, over the sclera. This region of the conjunctiva is tightly bound to the underlying sclera by Tenon's capsule and moves with the eyeball movements. synonym: "ocular conjunctiva" EXACT [Wikipedia:Conjunctiva] is_a: UBERON:0010305 {source="FMA"} ! region of conjunctiva xref: FMA:59024 ! bulbar conjunctiva xref: ncithesaurus:Bulbar_Conjunctiva ! bulbar conjunctiva xref: SCTID:264509009 ! Entire bulbar conjunctiva xref: UMLS:C0229275 [Term] id: UBERON:0010307 name: conjunctival fornix def: "line of reflexion of the conjunctiva from the eyelid to the eyeball." [http://medical-dictionary.thefreedictionary.com/conjunctival+fornix] comment: Forms the junction between the bulbar and palpebral conjunctivas. It is loose and flexible, allowing the free movement of the lids and eyeball synonym: "fornix conjunctiva" EXACT LATIN [Wikipedia:Conjunctiva] is_a: UBERON:0010305 {source="FMA"} ! region of conjunctiva xref: FMA:59016 ! conjunctival fornix xref: SCTID:276831007 ! Structure of conjunctival fornix [Term] id: UBERON:0001812 name: palpebral conjunctiva comment: lines the eyeballs synonym: "eyelid conjunctiva" RELATED [] synonym: "tunica conjunctiva palpebrum" EXACT [] synonym: "tarsal conjunctiva" EXACT [Wikipedia:Conjunctiva] xref: FMA:59025 ! Palpebral conjunctiva xref: MA:0001265 ! palpebral conjunctiva xref: ncithesaurus:Palpebral_Conjunctiva ! Palpebral Conjunctiva is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001711 ! eyelid relationship: part_of UBERON:0001811 {source="FMA"} ! conjunctiva xref: SCTID:280666005 ! Entire palpebral conjunctiva xref: UMLS:C0229274 [Term] id: UBERON:0006763 name: epithelium of conjunctiva def: "Layer of nonkeratinized squamous epithelium lining the conjunctiva, overlying scleral tissue" [] synonym: "conjunctiva epithelium" EXACT [FMA:62131] synonym: "conjunctival epithelium" EXACT [BTO:0005131] xref: FMA:62131 ! epithelium of conjunctiva xref: EFO:0001916 ! conjunctival epithelium xref: BTO:0005131 ! conjunctival epithelium is_a: UBERON:0010304 {source="FMA"} ! nonkeratinizing stratified squamous epithelium relationship: part_of UBERON:0001811 {source="BTO"} ! conjunctiva intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001811 ! conjunctiva xref: ncithesaurus:Conjunctival_Epithelium ! Conjunctival Epithelium xref: UMLS:C1179037 [Term] id: UBERON:0010366 ! conjunctival vasculature name: conjunctival vasculature synonym: "conjunctival veins" EXACT [FMA:70887] synonym: "conjunctival veins set" EXACT [FMA:70887] synonym: "venae conjunctivales" EXACT LATIN [FMA:TA] synonym: "set of conjunctival veins" EXACT [FMA:70887] intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001811 ! conjunctiva xref: FMA:70887 ! set of conjunctival veins (also: UBERON:0010367 'conjunctival vein') def: "A vasculature that is part of a conjunctiva." [OBOL:automatic] [Term] id: UBERON:0010367 name: conjunctival vein synonym: "conjunctival blood vessel" BROAD [] intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001811 ! conjunctiva relationship: part_of UBERON:0010366 ! conjunctival vasculature xref: FMA:70887 ! set of conjunctival veins (also: UBERON:0010366 'conjunctival vasculature') xref: SCTID:149885003 ! Entire conjunctival vein def: "A vein that is part of a conjunctiva." [OBOL:automatic] [Term] id: UBERON:0001813 name: somatic nerve plexus def: "A nerve plexus that is part of a somatic nervous system [Automatically generated definition]." [OBOL:automatic] comment: TODO - check synonym: "plexus of spinal nerves" EXACT [FMA:5903] synonym: "spinal nerve plexus" EXACT [FMA:5903] xref: FMA:5903 ! Somatic nerve plexus xref: VHOG:0000925 ! spinal nerve plexus xref: MA:0000235 ! spinal nerve plexus xref: ncithesaurus:Spinal_Nerve_Plexus ! Spinal Nerve Plexus xref: EHDAA2:0001899 ! spinal nerve plexus xref: EMAPA:16987 ! nerve plexus of spinal intersection_of: UBERON:0001810 ! nerve plexus intersection_of: part_of UBERON:0000012 ! somatic nervous system synonym: "plexus nervorum spinalium" EXACT LATIN [FMA:TA, FMA:5903] xref: SCTID:42280003 ! Spinal nerve plexus xref: UMLS:C0228603 [Term] id: UBERON:0001814 name: brachial nerve plexus def: "The brachial plexus is an arrangement of nerve fibers, running from the spine, formed by the ventral rami of the lower cervical and upper thoracic nerve root, specifically from below the fifth cervical vertebra to above the first thoracic vertebra. It proceeds through the neck, the axilla (armpit region) and into the arm. [WP,unvetted]." [Wikipedia:Brachial_plexus] comment: check superclass - nerve vs collection of fibers vs junction; note that FMA also has 'brachial autonomic nerve plexus' subset: uberon_slim synonym: "brachial plexus" EXACT [MA:0001180] synonym: "plexus brachialis" RELATED [Wikipedia:Brachial_plexus] synonym: "plexus brachialis" RELATED LATIN [Wikipedia:Brachial_plexus] xref: EHDAA:3782 ! brachial plexus xref: FMA:5906 ! Brachial nerve plexus xref: GAID:842 ! brachial plexus xref: VHOG:0000372 ! brachial plexus xref: MA:0001180 ! brachial plexus xref: ncithesaurus:Brachial_Plexus ! Brachial Plexus xref: OpenCyc:Mx4rwNWmO5wpEbGdrcN5Y29ycA ! brachial plexus xref: EHDAA2:0000180 ! brachial plexus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3a/Gray808.png/200px-Gray808.png xref: EMAPA:16988 ! brachial plexus xref: MESH:A08.800.800.720.050 ! brachial plexus is_a: UBERON:0001813 {source="MA"} ! somatic nerve plexus relationship: overlaps UBERON:0002102 ! forelimb xref: SCTID:181002002 ! Entire brachial plexus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c9/Brachial_plexus_color.svg/750px-Brachial_plexus_color.svg.png property_value: external_definition "A nerve plexus originating from the anterior branches of the last four cervical and the first thoracic spinal nerves, giving off many of the principal nerves of the shoulder, chest, and arms. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000372", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/brachial+plexus", source="http://bgee.unil.ch/"} property_value: homology_notes "To reach the muscles, dermatomes, and other structures of the limbs, some of the neurons in the spinal nerves come together in the plexus at the base of the limb. Such plexuses occur in all gnathostomes, and they reach their highest complexity among mammals and birds in which the cervical plexus supplies many ventral neck muscles, the brachial plexus supplies the pectoral appendage, a lumbosacral plexus supplies the pelvic appendage, and a coccygeal plexus supplies some of the pelvic muscles.[well established][VHOG]" xsd:string {external_class="VHOG:0000372", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.436", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0006090 [Term] id: UBERON:0001815 name: lumbosacral nerve plexus def: "The anterior divisions of the lumbar nerve, sacral nerve, and coccygeal nerves form the lumbosacral plexus, the first lumbar nerve being frequently joined by a branch from the twelfth thoracic. For descriptive purposes this plexus is usually divided into three parts: lumbar plexus sacral plexus pudendal plexus [WP,unvetted]." [Wikipedia:Lumbosacral_plexus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lumbosacral plexus" EXACT [] xref: EHDAA:4673 ! lumbosacral plexus xref: FMA:5907 ! Lumbosacral nerve plexus xref: GAID:849 ! lumbosacral plexus xref: MA:0001181 ! lumbosacral plexus xref: ncithesaurus:Lumbosacral_Plexus ! Lumbosacral Plexus xref: OpenCyc:Mx4rvzYo75wpEbGdrcN5Y29ycA ! lumbosacral plexus xref: VHOG:0000926 ! lumbo-sacral plexus xref: EHDAA2:0001040 ! lumbosacral plexus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Gray822.png/200px-Gray822.png xref: EMAPA:17587 ! lumbo-sacral plexus xref: MESH:A08.800.800.720.450 ! lumbosacral plexus is_a: UBERON:0001813 ! somatic nerve plexus synonym: "plexus lumbosacralis" EXACT LATIN [FMA:TA, FMA:5907] xref: SCTID:181049003 ! Entire lumbosacral plexus synonym: "plexus lumbosacralis" RELATED LATIN [Wikipedia:Lumbosacral_plexus] xref: http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray822.png property_value: homology_notes "To reach the muscles, dermatomes, and other structures of the limbs, some of the neurons in the spinal nerves come together in the plexus at the base of the limb. Such plexuses occur in all gnathostomes, and they reach their highest complexity among mammals and birds in which the cervical plexus supplies many ventral neck muscles, the brachial plexus supplies the pectoral appendage, a lumbosacral plexus supplies the pelvic appendage, and a coccygeal plexus supplies some of the pelvic muscles.[well established][VHOG]" xsd:string {external_class="VHOG:0000926", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.436", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0024093 [Term] id: UBERON:0001817 name: lacrimal gland def: "Lobular organ the parenchyma of which consists of glandular acini which communicate the lacrimal sac. Examples: There only two instances, right lacrimal and left lacrimal glands[FMA]. The lacrimal glands are paired almond-shaped glands, one for each eye, that secrete the aqueous layer of the tear film. They are situated in the upper, outer portion of each orbit. Inflammation of the lacrimal glands is called dacryoadenitis[WP]." [Wikipedia:Lacrimal_gland] subset: uberon_slim xref: FMA:59101 ! Lacrimal gland xref: VHOG:0001476 ! lacrimal gland xref: MA:0001296 ! lacrimal gland xref: ncithesaurus:Lacrimal_Gland xref: EFO:0001389 ! lacrimal gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Gray896.png/200px-Gray896.png xref: BTO:0000044 ! tear gland xref: EV:0100339 ! lacrimal gland synonym: "tear gland" RELATED [BTO:0000044] is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0001750 ! lacrimal apparatus relationship: part_of UBERON:0002330 ! exocrine system xref: SCTID:181147003 ! Entire lacrimal gland subset: organ_slim synonym: "glandula lacrimalis" RELATED LATIN [Wikipedia:Lacrimal_gland] synonym: "preorbital gland" RELATED SENSU [Wikipedia:Preorbital_gland] xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Gray896.png property_value: external_definition "The preorbital gland is a paired exocrine gland found in many species of hoofed animals, which is homologous to the lacrimal gland found in humans. These glands are trenchlike slits of dark blue to black, nearly bare skin extending from the medial canthus of each eye. They are lined by a combination of sebaceous and sudoriferous glands, and they produce secretions which contain pheromones and other semiochemical compounds. Ungulates frequently deposit these secretions on twigs and grass as a means of communication with other animals. The preorbital gland serves different roles in different species. Pheromone-containing secretions from the preorbital gland may serve to establish an animal's dominance (especially in preparation for breeding), mark its territory, or simply to produce a pleasurable sensation to the animal. Because of its critical role in scent marking, the preorbital gland is usually considered as a type of scent gland. A further function of these glands may be to produce antimicrobial compounds against skin pathogens. Antimicrobial compounds found in these glands may be biosynthesized by the animal itself, or by microorganisms that live in these glands[Wikipedia:Preorbital_gland]." xsd:string {source="Wikipedia:Preorbital_gland"} xref: UMLS:C0022907 [Term] id: UBERON:0013226 name: accessory lacrimal gland def: "Serous gland with distended lumen. It includes the gland of Krause in the lacrimal sac and the gland of Wolfring on the inner surface of the upper eyelid. (NCI)" [ncithesaurus:Accessory_Lacrimal_Gland] comment: Editor notes: may be re-classified as a sibling on lacrimal gland synonym: "glandulae lacrimales accessoriae" EXACT LATIN [] is_a: UBERON:0001817 ! lacrimal gland xref: SCTID:278360002 ! Accessory lacrimal gland xref: ncithesaurus:Accessory_Lacrimal_Gland ! accessory lacrimal gland xref: UMLS:C0266586 [Term] id: UBERON:0013224 name: Ciaccio's gland def: "Ciaccio's glands are small tubular accessory lacrimal glands (glandulae lacrimales accessoriae) found in the lacrimal caruncle of the eyelid. They are located in the upper border of the tarsus, approximately in the middle between the extremities of the tarsal glands. Sometimes they are situated slightly above the tarsus. There are usually 2 to 5 of these glands in the upper eyelid, and their function is to produce tears which are secreted onto the surface of the conjunctiva. They are named after Italian anatomist Giuseppe Vincenzo Ciaccio (1824b1901), who described these glands in 1874. They are sometimes called Wolfring's glands after Polish ophthalmologist Emilj von Wolfring (1832-1906), who described them during the same time period as did Ciaccio. Another type of accessory lacrimal gland are Krause's glands, which are smaller, more numerous than Ciaccio's glands and are found along the superior and inferior fornices of the conjunctival sac." [Wikipedia:Ciaccio's_glands] synonym: "gland of Wolfring" EXACT [Wikipedia:Ciaccio's_glands, ncithesaurus:Gland_of_Wolfring] synonym: "Wolfring's gland" EXACT [Wikipedia:Ciaccio's_glands] synonym: "gland of Wolfring and Ciacco" EXACT [SCTID:278361003] is_a: UBERON:0013226 ! accessory lacrimal gland relationship: part_of UBERON:0001711 {source="ncithesaurus"} ! eyelid xref: ncithesaurus:Gland_of_Wolfring ! gland of wolfring xref: SCTID:278361003 ! Gland of Wolfring and Ciacco [Term] id: UBERON:0011186 name: Krause's gland def: "small, mucous accessory lacrimal glands that are found underneath the eyelid where the upper and lower conjuctivae meet. Their ducts unite into a rather long sinus which open into the fornix conjunctiva. There are approximately forty Krause glands in the region of the upper eyelid, and around 6 to 8 in the region of the lower lid. The function of these glands are to produce tears which are secreted onto the surface of the conjuctiva" [Wikipedia:Krause's_glands] synonym: "accessory lacrimal gland" BROAD [FMA:59056] synonym: "Krause gland" EXACT [FMA:59056] synonym: "conjunctival gland" BROAD [FMA:59056] is_a: UBERON:0013226 ! accessory lacrimal gland relationship: part_of UBERON:0001351 {source="ncithesaurus"} ! lacrimal sac xref: FMA:59056 ! conjunctival gland xref: ncithesaurus:Gland_of_Krause ! gland of krause xref: SCTID:23492003 ! Conjunctival glands xref: SCTID:278359007 ! Conjunctival gland xref: UMLS:C1306642 [Term] id: UBERON:0013227 name: crypt of Henle def: "Crypts of Henle are microscopic pockets found in scattered sections of the conjunctiva around the eyeball. They are responsible for secreting mucin, a proteinous substance that makes up the inner layer of tears. It coats the cornea to provide a hydrophilic layer that allows for even distribution of the tear film. The layer of mucin allows tears to glide evenly across the eye’s surface[WP]." [Wikipedia:Crypts_of_Henle] synonym: "crypts of Henle" EXACT [Wikipedia:Crypts_of_Henle] synonym: "gland of Henle" EXACT [] synonym: "Henle's gland" EXACT [Wikipedia:Crypts_of_Henle] is_a: UBERON:0013226 ! accessory lacrimal gland xref: SCTID:278362005 ! Gland of Henle [Term] id: UBERON:0013228 name: sweat gland of eyelid def: "Glands of Moll, also known as ciliary glands, are modified apocrine sweat glands that are found on the margin of the eyelid. They are next to the base of the eyelashes, and anterior to the Meibomian glands within the distal eyelid margin. These glands are relatively large and tubular-shaped. The glands of Moll are named after Dutch oculist Jacob Anton Moll (1832–1914). Glands of Moll empty into the adjacent lashes. Glands of Moll and Zeis secrete lipid that adds to the superficial layer of the tear film, retarding evaporation. The glands of Moll are prone to infection and blockage of its duct with sebum and cell debris. Blockage of the gland's duct causes swelling which can manifest itself as a stye." [Wikipedia:Gland_of_Moll] synonym: "ciliary gland" EXACT [FMA:59159] synonym: "ciliary gland of moll" EXACT [FMA:59159] synonym: "ciliary sweat gland of eyelid" EXACT [FMA:59159] synonym: "gland of Moll" EXACT [FMA:59159] synonym: "Moll's gland" EXACT [FMA:59159] intersection_of: UBERON:0000382 ! apocrine sweat gland intersection_of: part_of UBERON:0001711 ! eyelid xref: FMA:59159 ! sweat gland of eyelid xref: SCTID:280586002 ! Entire sweat gland of eyelid [Term] id: UBERON:0013229 name: eyelid gland synonym: "gland of eyelid" EXACT [] intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001711 ! eyelid xref: SCTID:280574000 ! Eyelid gland [Term] id: UBERON:0013231 name: sebaceous gland of eyelid def: "Glands of Zeis are unilobar sebaceous glands located on the margin of the eyelid. The glands of Zeis service the eyelash. These glands produce an oily substance that is issued through the excretory ducts of the sebaceous lobule into the middle portion of the hair follicle. In the same area of the eyelid, near the base of the eyelashes are sweat glands called the \"glands of Moll\". If eyelashes are not kept clean, conditions such as folliculitis may take place, and if the sebaceous gland becomes infected, it can lead to abscesses and styes. The glands of Zeis are named after German ophthalmologist Eduard Zeis (1807b68)." [Wikipedia:Gland_of_Zeis] synonym: "ciliary sebaceous gland of eyelid" EXACT [FMA:59191] synonym: "gland of Zeiss" EXACT [FMA:59191] synonym: "gland of Zeis" EXACT [] intersection_of: UBERON:0001821 ! sebaceous gland intersection_of: part_of UBERON:0001711 ! eyelid xref: FMA:59191 ! sebaceous gland of eyelid [Term] id: UBERON:0001818 name: tarsal gland def: "The meibomian glands (or tarsal glands) are a special kind of sebaceous glands at the rim of the eyelids, responsible for the supply of sebum, an oily substance that prevents evaporation of the eye's tear film, prevents tear spillage onto the cheek, and makes the closed lids airtight. There are approximately 50 glands on the upper eyelids and 25 glands on the lower eyelids. The glands are named after Heinrich Meibom (1638-1700), a German physician. [WP,unvetted]." [Wikipedia:Meibomian_gland] subset: uberon_slim synonym: "glandula tarsales" EXACT [] synonym: "gland of Meibom" EXACT [] synonym: "Meibomian gland" EXACT [] synonym: "palpebral gland" RELATED [] xref: FMA:59104 ! Tarsal gland xref: GAID:899 ! meibomian gland xref: MA:0001249 ! meibomian gland xref: ncithesaurus:Meibomian_Gland ! Meibomian Gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Gray1205.png/200px-Gray1205.png xref: BTO:0004165 ! meibomian gland xref: MESH:A09.371.337.614 ! meibomian gland intersection_of: UBERON:0001821 ! sebaceous gland intersection_of: part_of UBERON:0004772 ! eyelid tarsus xref: SCTID:280585003 ! Entire meibomian gland subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Gray1205.png xref: UMLS:C0025181 [Term] id: UBERON:0004000 name: tarsal gland acinus synonym: "palpebral gland acinus" RELATED [] synonym: "meibomian gland acinus" EXACT [] synonym: "acinus of tarsal gland" EXACT [] def: "." [MP:0009935] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0001818 ! tarsal gland [Term] id: UBERON:0001819 name: palpebral fissure def: "Orifice separating upper and lower eyelids. In the human adult this measures about 10mm vertically and 30 mm horizontally. It can be reduced in size in fetal alcohol syndrome. In Trisomy 9 the palpebral fissures can be upslanting. [WP,modified]." [Wikipedia:Palpebral_fissure] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:59110 ! Palpebral fissure xref: MA:0001266 ! palpebral fissure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a9/Gray892.png/200px-Gray892.png is_a: UBERON:0000161 {source="FMA"} ! orifice relationship: part_of UBERON:0001711 {source="MA"} ! eyelid xref: SCTID:280576003 ! Entire palpebral fissure synonym: "rima palpebrarum" RELATED LATIN [Wikipedia:Palpebral_fissure] xref: http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray892.png [Term] id: UBERON:0007771 name: epidermis gland synonym: "gland of epidermis" EXACT [FMA:59153] synonym: "epidermal gland" EXACT [] xref: FMA:59153 ! gland of epidermis intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001003 ! epidermis subset: grouping_class def: "A gland that is part of a epidermis." [OBOL:automatic] [Term] id: UBERON:0001820 name: sweat gland def: "Sweat glands are exocrine glands, found in the skin of all mammal species, that are used for body temperature regulation. In humans a system of apocrine - and merocrine sweat glands is the main method of cooling. Many other mammals rely on panting or other means as a primary source of cooling, but still use sweat glands to aid in body temperature regulation. Sweat also serves a purpose of increasing friction on the palms of hands or the pads of paws. Both apocrine and merocrine sweat glands contain myoepithelial cells (from Greek myo-, 'muscle'), specialized epithelial cells located between the gland cells and the underlying basal lamina. Myoepithelial cell contractions squeeze the gland and discharge the accumulated secretions. The secretory activities of the gland cells and the contractions of myoepithelial cells are controlled by both the autonomic nervous system and by the circulating hormones. Additionally, ceruminous glands, which produce ear wax, and mammary glands, which produce milk, are frequently considered to be modified sweat glands. [WP,unvetted]." [Wikipedia:Sweat_gland, Wikipedia:Sweat_gland] comment: todo - check if all sweat glands are epidermal - see EMAPA:29743 subset: uberon_slim synonym: "glandula sudorifera" RELATED [BTO:0001331] synonym: "sudoriferous gland" RELATED [BTO:0001331] synonym: "sudoriparous gland" RELATED [BTO:0001331] xref: BTO:0001331 xref: FMA:59152 ! Sweat gland xref: GAID:943 ! sweat gland xref: VHOG:0001467 ! sweat gland xref: MA:0000150 ! sweat gland xref: OpenCyc:Mx4rvVjx15wpEbGdrcN5Y29ycA xref: ncithesaurus:Sweat_Gland ! Sweat Gland xref: OpenCyc:Mx4rvVjx15wpEbGdrcN5Y29ycA ! sweat gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Skin.svg/200px-Skin.svg.png xref: MESH:A10.336.899 ! sweat gland xref: EV:0100160 ! sweat gland is_a: UBERON:0002365 {source="MA"} ! exocrine gland intersection_of: UBERON:0002530 ! gland intersection_of: secretes UBERON:0001089 ! sweat relationship: part_of UBERON:0001003 {source="FMA"} ! epidermis relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: has_quality PATO:0001873 {source="Wikipedia:Tubular_gland", notes="coiled tubular"} ! cylindrical xref: SCTID:361700009 ! Entire sweat gland subset: organ_slim relationship: develops_from UBERON:0005089 {evidence="definitional"} ! sweat gland placode xref: http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg property_value: external_definition "A gland that secretes sweat, found in the dermis or subcutaneous tissue, opening by a duct on the body surface. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001467", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/sweat+gland", source="http://bgee.unil.ch/"} property_value: homology_notes "Sweat glands (also called sudoriferous glands) are unique to mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0001467", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.101", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0038989 [Term] id: UBERON:0001821 name: sebaceous gland def: "A holocrine gland that secretes sebum into the hair follicles, or in hairless areas into ducts.[MP]." [Wikipedia:Sebaceous_gland, MP:0000647] comment: Usage notes: sebaceous glands are also found in glabrous areas of eyelids, nose, penis, labia minora and nipples, and do not always secrete into hair follices. This causes some confusion in classification. In addition some structures, such as preputial glands are sometimes called 'modified' sebaceous glands, implying a non-subclass relationship. we follow MP and MA in keeping this class generic and creating a distinct subclass for sebaceuous glands of the skin. The FMA class may be better placed under this subclass. subset: uberon_slim synonym: "glandula sebaceae" RELATED [BTO:0001980] synonym: "glandula sebacea" RELATED LATIN [Wikipedia:Sebaceous_gland] synonym: "sebaceous follicle" RELATED [BTO:0001980] xref: FMA:59160 ! Sebaceous gland xref: GAID:900 ! sebaceous gland xref: VHOG:0001468 ! sebaceous gland xref: MA:0002565 ! sebaceous gland xref: ncithesaurus:Sebaceous_Gland ! Sebaceous Gland xref: BTO:0001980 ! sebaceous gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/49/HairFollicle.png/200px-HairFollicle.png xref: MESH:A10.336.827 ! sebaceous gland xref: EV:0100161 ! sebaceous gland is_a: UBERON:0012344 {source="Wikipedia"} ! holocrine gland relationship: part_of UBERON:0002330 ! exocrine system relationship: part_of UBERON:0001003 {source="FMA", inconsistent_with="BTO"} ! epidermis relationship: part_of UBERON:0006003 ! skin adnexa relationship: secretes UBERON:0001866 ! sebum relationship: only_in_taxon NCBITaxon:40674 {source="VHOG"} ! Mammalia xref: SCTID:361697005 ! Entire sebaceous gland subset: organ_slim relationship: develops_from UBERON:0005088 {evidence="definitional"} ! sebaceous gland placode xref: http://upload.wikimedia.org/wikipedia/commons/4/49/HairFollicle.png property_value: external_definition "Any of the numerous holocrine glands in the dermis that empty into a hair follicle and produce and secrete sebum. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001468", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/sebaceous+gland", source="http://bgee.unil.ch/"} property_value: homology_notes "Sebaceous glands are also limited to mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0001468", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.102", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0036505 [Term] id: UBERON:0003487 name: skin sebaceous gland def: "A holocrine gland of the dermis that secretes sebum into hair follicles." [MP:0009535] synonym: "sebaceous gland of skin" EXACT [OBOL:automatic] synonym: "cutaneous sebaceous gland" EXACT [] xref: MA:0000149 ! skin sebaceous gland xref: SCTID:115977007 ! Cutaneous sebaceous gland is_a: UBERON:0001821 ! sebaceous gland relationship: part_of UBERON:0002097 ! skin of body relationship: part_of UBERON:0011932 {source="FMA"} ! pilosebaceous unit [Term] id: UBERON:0001822 name: orbital septum def: "a membranous sheet that acts as the anterior boundary of the orbit. It extends from the orbital rims to the eyelids[WP]." [Wikipedia:Orbital_septum] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:59328 ! Orbital septum xref: MA:0001259 ! orbital septum is_a: UBERON:0003037 ! septum is_a: UBERON:0000094 ! membrane organ relationship: part_of UBERON:0002204 ! musculoskeletal system relationship: surrounds UBERON:0001697 ! orbital region relationship: part_of UBERON:0004772 ! eyelid tarsus xref: SCTID:368859002 ! Entire orbital septum subset: organ_slim synonym: "septum orbitale" RELATED LATIN [Wikipedia:Orbital_septum] xref: http://upload.wikimedia.org/wikipedia/commons/1/18/Gray891.png [Term] id: UBERON:0011576 name: supra-orbital region of bone def: "a bony ridge located above the eye sockets of all primates. In Homo sapiens sapiens (modern humans) the eyebrows are located on their lower margin[WP]." [Wikipedia:Supraorbital_ridge] comment: see also: xref: AAO:0000590 ! supraorbital flange and teleost supraorbital bone is_a: UBERON:0008001 ! irregular bone relationship: part_of UBERON:0003113 ! dermatocranium relationship: part_of UBERON:0001697 ! orbital region xref: ncithesaurus:Orbital_Ridge ! orbital ridge xref: FMA:53097 ! supra-orbital margin of frontal bone xref: FMA:57137 ! supraorbital surface of frontal bone synonym: "eyebrow bone" RELATED [Wikipedia:Supraorbital_ridge] synonym: "supraorbital arch" RELATED [Wikipedia:Supraorbital_ridge] synonym: "frontal torus" RELATED [Wikipedia:Supraorbital_ridge] synonym: "supraorbital torus" RELATED [Wikipedia:Supraorbital_ridge] synonym: "superciliary ridge" RELATED [Wikipedia:Supraorbital_ridge] synonym: "arcus superciliaris " RELATED LATIN [Wikipedia:Supraorbital_ridge] synonym: "supraorbital margin" RELATED [Wikipedia:Supraorbital_ridge] synonym: "margin of the orbit" RELATED [Wikipedia:Supraorbital_ridge] synonym: "frontal torus" NARROW SENSU [Wikipedia:Supraorbital_ridge] synonym: "supraorbital torus" NARROW SENSU [Wikipedia:Supraorbital_ridge] synonym: "supra-orbital margin of frontal bone" RELATED [FMA:53097] synonym: "margo supraorbitalis (os frontale)" RELATED [FMA:53097] synonym: "supraorbital surface of frontal bone" RELATED [FMA:57137] xref: UMLS:C2826587 property_value: taxon_notes "Neanderthals have a Supraorbital torus, a prominent, trabecular (spongy) brow ridge." xsd:string {source="http://en.wikipedia.org/wiki/Neanderthal_anatomy", taxon="NCBITaxon:63221"} [Term] id: UBERON:0001824 name: mucosa of larynx def: "the mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx." [MP:0002261] comment: This class was created automatically from a combination of ontologies synonym: "laryngeal mucosa" EXACT [] synonym: "larynx mucosa" EXACT [] synonym: "mucous membrane of larynx" EXACT [] synonym: "larynx mucosa of organ" EXACT [OBOL:automatic] synonym: "larynx mucous membrane" EXACT [OBOL:automatic] synonym: "larynx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of larynx" EXACT [OBOL:automatic] synonym: "organ mucosa of larynx" EXACT [OBOL:automatic] xref: FMA:59662 ! Mucosa of larynx xref: GAID:301 ! laryngeal mucosa xref: MA:0001766 ! larynx mucosa xref: ncithesaurus:Laryngeal_Mucosa ! Laryngeal Mucosa xref: EMAPA:18334 ! mucous membranes (also: UBERON:0004785 'respiratory system mucosa') xref: MESH:A04.329.597 ! laryngeal mucosa is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001737 ! larynx synonym: "tunica mucosa laryngis" EXACT LATIN [FMA:TA, FMA:59662] xref: SCTID:361940006 ! Entire mucous membrane of larynx xref: UMLS:C0023053 [Term] id: UBERON:0001825 name: paranasal sinus def: "Paranasal sinuses are air-filled spaces, communicating with the nasal cavity, within the bones of the skull and face. [WP,unvetted]." [Wikipedia:Paranasal_sinuses] comment: Arise as epithelial lined diverticula of the lining of the nasal cavity. The extent of sinus development varies with species, most of the development occurs postnatally subset: uberon_slim synonym: "nasal sinus" RELATED [GAID:355] synonym: "sinus" BROAD [] xref: FMA:59679 ! Paranasal sinus xref: GAID:355 ! paranasal sinus xref: MA:0000431 ! paranasal sinus xref: ncithesaurus:Paranasal_Sinus ! Paranasal Sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Nnh_front.svg/200px-Nnh_front.svg.png xref: MESH:A04.531.621 ! paranasal sinus xref: EHDAA:6489 ! sinus xref: EV:0100038 ! sinus is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0000033 ! head relationship: continuous_with UBERON:0001707 ! nasal cavity xref: SCTID:181203001 ! Entire nasal sinus xref: UMLS:C0030471 [Term] id: UBERON:0013074 name: cornual sinus is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0006967 ! horn xref: SCTID:53994006 ! Cornual sinus [Term] id: UBERON:0001827 name: lacrimal gland secretion def: "A substance secreted the lacrimal gland.[Automatically generated definition]" [Wikipedia:Tear, OBOL:automatical] synonym: "tear" EXACT [FMA:59756] synonym: "tears" EXACT PLURAL [] synonym: "lacrimal secretion" EXACT [] subset: uberon_slim xref: ENVO:02000034 xref: FMA:59756 ! Tear xref: GAID:1173 ! tear xref: MA:0002508 ! tear xref: ncithesaurus:Tear ! Tear xref: BTO:0001499 ! tear xref: galen:Tear ! tear xref: galen:Tears ! tears xref: MESH:A12.200.882 ! tear intersection_of: UBERON:0000456 ! bodily secretion intersection_of: secreted_by UBERON:0001817 ! lacrimal gland xref: UMLS:C0039409 [Term] id: UBERON:0001828 name: gingiva def: "The fibrous investing tissue, covered by keratinized epithelium, that immediately surrounds a tooth and is contiguous with its periodontal ligament and with the mucosal tissues of the mouth[Glossary of Periodontal Terms 2001]." [Wikipedia:Gingiva, ISBN10:0013002015] comment: Editor notes: FMA has a 3-level breakdown of jaws into: region, jaw (skeleton+gums), skeleton. subset: uberon_slim synonym: "gingival mucosa" RELATED [] synonym: "gums" EXACT [] synonym: "gum" EXACT [FMA:59762] synonym: "gum tissue" EXACT [UBERON:cjm] xref: BTO:0000519 xref: FMA:59762 ! Gingiva xref: GAID:1257 ! gingiva xref: galen:Gingiva xref: VHOG:0001269 ! gum xref: MA:0000342 ! gingiva xref: OpenCyc:Mx4rvViWnZwpEbGdrcN5Y29ycA xref: ncithesaurus:Gingiva ! Gingiva xref: EFO:0001925 ! gum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Tooth_Section.svg/200px-Tooth_Section.svg.png xref: MESH:A14.254.646.480 ! gingiva xref: EV:0100064 ! gum is_a: UBERON:0000344 ! mucosa relationship: part_of UBERON:0011595 ! jaw region relationship: part_of UBERON:0003729 {source="Carranza"} ! mouth mucosa relationship: continuous_with UBERON:0003729 {source="ISBN10:0013002015"} ! mouth mucosa relationship: adjacent_to UBERON:0004103 ! alveolar ridge relationship: adjacent_to UBERON:0008266 ! periodontal ligament xref: SCTID:181224006 ! Entire gingiva xref: http://upload.wikimedia.org/wikipedia/commons/2/2e/Tooth_Section.svg property_value: has_relational_adjective "gingival" xsd:string xref: UMLS:C0017562 [Term] id: UBERON:0011601 name: gingiva of upper jaw synonym: "upper jaw gingiva" EXACT [FMA:59763] synonym: "gum of maxilla" EXACT [] intersection_of: UBERON:0001828 ! gingiva intersection_of: part_of UBERON:0001709 ! upper jaw region xref: FMA:59763 ! gingiva of upper jaw xref: EMAPA:18970 ! gum of upper jaw xref: SCTID:304703001 ! Entire gum of maxilla synonym: "gum of upper jaw" EXACT [EMAPA:18970] def: "A gingiva that is part of a upper jaw region." [OBOL:automatic] [Term] id: UBERON:0011602 name: gingiva of lower jaw synonym: "lower jaw gingiva" EXACT [FMA:59764] synonym: "gum of mandible" EXACT [] intersection_of: UBERON:0001828 ! gingiva intersection_of: part_of UBERON:0001710 ! lower jaw region xref: FMA:59764 ! gingiva of lower jaw xref: EMAPA:18967 ! gum of lower jaw synonym: "gum of lower jaw" EXACT [EMAPA:18967] xref: SCTID:304704007 ! Entire gum of mandible def: "A gingiva that is part of a lower jaw region." [OBOL:automatic] [Term] id: UBERON:0001829 name: major salivary gland def: "the three largest glands of the oral cavity that secrete most of the saliva, including the parotid, submandibular, and sublingual glands." [MP:0003792] comment: There are 3 pairs of major salivary glands in human and mouse[ISBN10:0123813611] xref: FMA:59788 ! Major salivary gland xref: MA:0002478 ! major salivary gland xref: ncithesaurus:Major_Salivary_Gland ! Major Salivary Gland xref: galen:MajorSalivaryGland ! major salivary gland is_a: UBERON:0002365 {source="MA"} ! exocrine gland relationship: part_of UBERON:0000165 {source="MA"} ! mouth relationship: in_lateral_side_of UBERON:0000165 ! mouth xref: SCTID:303049006 ! Entire major salivary gland subset: organ_slim xref: UMLS:C0930553 [Term] id: UBERON:0001830 name: minor salivary gland def: "the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands[MP]. There are over 600 minor salivary glands located throughout the oral cavity within the lamina propria of the oral mucosa. They are 1-2mm in diameter and unlike the other glands, they are not encapsulated by connective tissue only surrounded by it. The gland is usually a number of acini connected in a tiny lobule. A minor salivary gland may have a common excretory duct with another gland, or may have its own excretory duct. Their secretion is mainly mucous in nature (except for Von Ebner's glands) and have many functions such as coating the oral cavity with saliva. Problems with dentures are usually associated with minor salivary glands[WP]." [Wikipedia:Salivary_gland#Minor_Salivary_Glands, MP:0003791] xref: FMA:59789 ! Minor salivary gland xref: GAID:940 ! minor salivary gland xref: MA:0002479 ! minor salivary gland xref: ncithesaurus:Minor_Salivary_Gland ! Minor Salivary Gland xref: galen:MinorSalivaryGland ! minor salivary gland xref: MESH:A10.336.779.650 ! minor salivary gland is_a: UBERON:0001044 ! salivary gland relationship: part_of UBERON:0002330 ! exocrine system relationship: part_of UBERON:0005334 ! oral lamina propria xref: SCTID:362177001 ! Entire minor salivary gland subset: organ_slim xref: UMLS:C0036099 [Term] id: UBERON:0001831 name: parotid gland def: "The parotid gland is the largest of the salivary glands. It is found wrapped around the mandibular ramus, and it secretes saliva through Stensen's duct into the oral cavity, to facilitate mastication and swallowing. [WP,unvetted]." [Wikipedia:Parotid_gland] comment: The mouse parotid, exorbital lacrimal gland and exocrine pancreas have similar histological appearances[ISBN10:0123813611] subset: uberon_slim synonym: "parotid" EXACT [] xref: BTO:0001004 ! parotid gland xref: FMA:59790 ! Parotid gland xref: GAID:938 ! parotid gland xref: VHOG:0000308 ! parotid gland xref: MA:0001585 ! parotid gland xref: ncithesaurus:Parotid_Gland ! Parotid Gland xref: EFO:0002558 ! parotid gland xref: galen:ParotidGland ! parotid gland xref: OpenCyc:Mx4rvqwyg5wpEbGdrcN5Y29ycA ! parotid gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/51/Illu_quiz_hn_02.jpg/200px-Illu_quiz_hn_02.jpg xref: EMAPA:18537 ! parotid xref: MESH:A10.336.779.464 ! parotid gland xref: EV:0100060 ! parotid gland is_a: UBERON:0001829 ! major salivary gland relationship: part_of UBERON:0001567 ! cheek relationship: develops_from UBERON:0008801 ! parotid gland primordium xref: AAO:0010095 ! parotid glands xref: SCTID:181234002 ! Entire parotid gland synonym: "glandula parotidea" RELATED LATIN [Wikipedia:Parotid_gland] xref: http://upload.wikimedia.org/wikipedia/commons/5/51/Illu_quiz_hn_02.jpg property_value: external_definition "A mammalian salivary gland located caudal to the ear. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-22, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000308", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The most common oral glands in mammals are the salivary glands. There are usually three primary pairs of salivary glands, named for their approximate positions: mandibular (submandibular or submaxillary), sublingual, and parotid.[well established][VHOG]" xsd:string {external_class="VHOG:0000308", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.525", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0001710 {source="FMA-abduced-lr"} ! lower jaw region xref: UMLS:C0030580 [Term] id: UBERON:0008801 ! parotid gland primordium name: parotid gland primordium is_a: UBERON:0001048 {source="Obol"} ! primordium xref: EHDAA2:0001413 ! parotid gland primordium xref: EHDAA:9246 ! parotid gland primordium [Term] id: UBERON:0001832 ! sublingual gland name: sublingual gland def: "The sublingual glands are salivary glands in the mouth. They lie anterior to the submandibular gland under the tongue, beneath the mucous membrane of the floor of the mouth. They are drained by 8-20 excretory ducts called the ducts of Rivinus. The largest duct, the sublingual duct (of Bartholin) joins the submandibular duct to drain through the sublingual caruncle. The sublingual gland consists mostly of Mucous acini capped with serous demilunes and is therefore categorized as a mixed gland. Most of the remaining small sublingual ducts open separately into the mouth on an elevated crest of mucous membrane, the sublingual fold, caused by the gland and on either side of the frenulum linguae. The chorda tympani nerve is secretomotor to the sublingual glands. [WP,unvetted]." [Wikipedia:Sublingual_gland] comment: Single lobed in mouse; largest acini of the 3 rodent salivary glands. In human and mouse, secretions are predominantly mucinous[ISBN10:0123813611] subset: uberon_slim synonym: "ductus sublingualis" EXACT [] synonym: "Rivinus' gland" EXACT [] synonym: "Rivinus gland" RELATED [BTO:0001315] synonym: "submaxillary gland" RELATED [MA:0001589] synonym: "sublingual salivary gland" RELATED [] xref: BTO:0001315 xref: FMA:59791 ! Sublingual gland xref: GAID:941 ! sublingual gland xref: VHOG:0000363 ! sublingual gland xref: MA:0001588 ! sublingual gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Gray1024.png/200px-Gray1024.png xref: EMAPA:18809 ! sublingual gland xref: MESH:A10.336.779.687 ! sublingual gland xref: EV:0100062 ! sublingual gland is_a: UBERON:0001829 {source="FMA"} ! major salivary gland relationship: develops_from UBERON:0006297 ! sublingual gland primordium xref: SCTID:362176005 ! Entire sublingual gland xref: ncithesaurus:Sublingual_Salivary_Gland ! Sublingual Salivary Gland synonym: "glandula sublingualis" RELATED LATIN [Wikipedia:Sublingual_gland] xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray1024.png property_value: external_definition "One of a pair of small salivary glands situated under the mucous membrane of the floor of the mouth, beneath the tongue. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000363", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/sublingual+gland", source="http://bgee.unil.ch/"} property_value: homology_notes "Most mammals have well-developed parotid, mandibular, and sublingual glands.[well established][VHOG]" xsd:string {external_class="VHOG:0000363", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.553", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0038553 [Term] id: UBERON:0001833 name: lip def: "One of the two fleshy folds which surround the opening of the mouth. " [Wikipedia:Lip, http://www.medterms.com/script/main/art.asp?articlekey=9458] subset: uberon_slim subset: vertebrate_core synonym: "lips" RELATED [] xref: FMA:59816 ! Lip xref: GAID:76 ! lip xref: VHOG:0000677 ! lip xref: MA:0000343 ! lip xref: ncithesaurus:Lip xref: OpenCyc:Mx4rvVi4U5wpEbGdrcN5Y29ycA xref: TAO:0007006 ! lip xref: ZFA:0007006 ! lip xref: BTO:0001647 ! lip xref: galen:Lip ! lip xref: OpenCyc:Mx4rvVi4U5wpEbGdrcN5Y29ycA ! lip xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/99/Mouth.jpg/200px-Mouth.jpg xref: MESH:A01.456.505.631.515 ! lip is_a: UBERON:0003102 ! surface structure relationship: surrounds UBERON:0000166 ! oral opening relationship: part_of UBERON:0000165 ! mouth relationship: never_in_taxon NCBITaxon:8782 ! Aves xref: SCTID:181221003 ! Entire lip synonym: "labia oris" RELATED LATIN [Wikipedia:Lip] xref: http://upload.wikimedia.org/wikipedia/commons/9/90/Lips.JPG property_value: external_definition "Surface structure that is one of the two fleshy folds surrounding the opening of the mouth.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0007006", date_retrieved="2012-08-14", source="ZFIN:curator", source="http:www.medterms.com/script/main/art.asp?articlekey=9458"} property_value: has_relational_adjective "labial" xsd:string xref: UMLS:C0023759 [Term] id: UBERON:0011592 ! future upper lip name: future upper lip is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: part_of UBERON:0001709 {source="EHDAA2"} ! upper jaw region relationship: develops_from UBERON:0004068 {notes="fusion"} ! medial nasal prominence relationship: develops_from UBERON:0005868 {notes="fusion"} ! maxillary prominence xref: EHDAA2:0002120 ! upper jaw future lip synonym: "upper jaw future lip" EXACT [EHDAA2:0002120] [Term] id: UBERON:0001834 name: upper lip alt_id: UBERON:0003391 def: "Lip that covers the upper portion of the mouth.[TAO]." [Wikipedia:Upper_lip, TAO:0001970] subset: uberon_slim subset: vertebrate_core synonym: "upper jaw lip" EXACT [UBERON:cjm] xref: FMA:59817 ! Upper lip xref: MA:0000919 ! upper lip xref: OpenCyc:Mx4rvWPv7pwpEbGdrcN5Y29ycA xref: ZFA:0005226 ! upper lip xref: OpenCyc:Mx4rvWPv7pwpEbGdrcN5Y29ycA ! upper lip xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d4/Illu01_head_neck.jpg/200px-Illu01_head_neck.jpg xref: EMAPA:17925 ! lip of upper jaw intersection_of: UBERON:0001833 ! lip intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: immediate_transformation_of UBERON:0011592 ! future upper lip xref: SCTID:245776003 ! Entire upper lip xref: TAO:0001970 ! upper lip synonym: "labium superius oris" RELATED LATIN [Wikipedia:Upper_lip] xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg xref: VHOG:0001750 ! upper lip property_value: external_definition "Lip that covers the upper portion of the mouth.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001970", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_definition "Lip that covers the lower portion of the mouth. [ZFIN:Curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001750", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0011596 name: future lower lip is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: part_of UBERON:0001710 {source="EHDAA2"} ! lower jaw region relationship: develops_from UBERON:0005867 {source="Wikipedia:Mandibular_prominence"} ! mandibular prominence xref: EHDAA2:0001020 ! lower jaw future lip (also: UBERON:0001835 'lower lip') synonym: "lower jaw future lip" EXACT [EHDAA2:0001020] [Term] id: UBERON:0001835 name: lower lip alt_id: UBERON:0003392 def: "Lip that covers the upper portion of the mouth.[TAO]." [Wikipedia:Lower_lip, TAO:0002060] subset: uberon_slim subset: vertebrate_core synonym: "lower jaw lip" EXACT [UBERON:cjm] xref: FMA:59818 ! Lower lip xref: MA:0000921 ! lower lip xref: OpenCyc:Mx4rv842UpwpEbGdrcN5Y29ycA xref: ZFA:0005225 ! lower lip xref: OpenCyc:Mx4rv842UpwpEbGdrcN5Y29ycA ! lower lip xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/99/Mouth.jpg/200px-Mouth.jpg xref: EHDAA2:0001020 ! lower jaw future lip (also: UBERON:0011596 'future lower lip') xref: EMAPA:17909 ! lip of lower jaw intersection_of: UBERON:0001833 ! lip intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: develops_from UBERON:0011596 ! lower jaw future lip xref: SCTID:245777007 ! Entire lower lip xref: ncithesaurus:Lower_Lip ! lower lip xref: TAO:0002060 ! lower lip synonym: "labium inferius oris" RELATED LATIN [Wikipedia:Lower_lip] xref: http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg property_value: external_definition "Lip that covers the lower portion of the mouth.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002060", date_retrieved="2012-08-14", source="TAO:wd"} xref: UMLS:C0458583 [Term] id: UBERON:0005402 name: philtrum def: "medial cleft extending from the nose to the upper lip" [Wikipedia:Philtrum] comment: Taxon notes: vestigial in humans. n humans, the philtrum is formed where the nasomedial and maxillary processes meet during embryonic development (colloquially known as Hulse lines). When these processes fail to fuse fully in humans, a cleft lip (sometimes called a 'hare lip') can result. A flattened or smooth philtrum can be a symptom of fetal alcohol syndrome or Prader-Willi syndrome synonym: "infranasal depression" RELATED [Wikipedia:Philtrum] synonym: "lip philtrum" EXACT [MA:0001577] xref: FMA:59819 ! Philtrum xref: MA:0001577 ! lip philtrum xref: EHDAA2:0001462 ! philtrum xref: EHDAA:9280 ! philtrum xref: EMAPA:17926 ! philtrum xref: VHOG:0000862 ! philtrum is_a: UBERON:0003102 ! surface structure is_a: UBERON:0006846 {source="EHDAA2"} ! groove relationship: part_of UBERON:0001834 {source="EMAPA"} ! upper lip relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: develops_from UBERON:0004068 {source="Wikipedia"} ! medial nasal prominence xref: SCTID:362087004 ! Entire philtrum [Term] id: UBERON:0011256 name: rhinarium def: "Moist, hairless, crenelated area around nostrils of some mammals" [Wikipedia:Rhinarium, http://anthro.palomar.edu/primate/glossary.htm] comment: Absent in Tarsiers is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0007827 ! external nose relationship: surrounds UBERON:0005928 ! external naris relationship: only_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: UBERON:0001836 name: saliva def: "In humans, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin[GO]." [GO:0046541, Wikipedia:Saliva] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "salivary gland secretion" EXACT [FMA:59862] xref: BTO:0001202 xref: ENVO:02000036 xref: FMA:59862 ! Saliva xref: GAID:1167 ! saliva xref: MA:0002507 ! saliva xref: MAT:0000444 ! saliva xref: OpenCyc:Mx4rvVjJ95wpEbGdrcN5Y29ycA xref: ncithesaurus:Saliva ! Saliva xref: galen:Saliva ! saliva xref: OpenCyc:Mx4rvVjJ95wpEbGdrcN5Y29ycA ! saliva xref: MESH:A12.200.666 ! saliva is_a: UBERON:0000456 ! bodily secretion relationship: has_function_in GO:0007586 ! digestion synonym: "saliva atomaris" RELATED LATIN [Wikipedia:Saliva] synonym: "sailva normalis" RELATED LATIN [Wikipedia:Saliva] synonym: "saliva molecularis" RELATED LATIN [Wikipedia:Saliva] property_value: has_relational_adjective "salivary" xsd:string xref: UMLS:C0036087 [Term] id: UBERON:0001837 name: duct of salivary gland def: "An intralobular duct found in salivary glands and involved in the production and transport of their secretions[BTO]." [Wikipedia:Salivary_duct, BTO:0005115] comment: check taxonomy coverage - define functionally? subset: uberon_slim synonym: "secretory duct" RELATED [BTO:0005115] synonym: "salivary duct" EXACT [] synonym: "salivary gland duct" EXACT [] xref: FMA:59908 ! Duct of salivary gland xref: GAID:939 ! salivary duct xref: MA:0001586 ! salivary duct xref: MESH:A10.336.779.640 ! salivary duct xref: BTO:0005115 ! salivary duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001044 ! salivary gland relationship: channel_for UBERON:0001836 ! saliva relationship: channels_from UBERON:0001044 ! salivary gland relationship: channels_into UBERON:0000165 ! mouth xref: SCTID:181238004 ! Entire salivary duct [Term] id: UBERON:0001838 name: sublingual duct def: "The excretory ducts of the sublingual gland are from eight to twenty in number. Of the smaller sublingual ducts (ducts of Rivinus), some join the submandibular duct; others open separately into the mouth, on the elevated crest of mucous membrane (plica sublingualis), caused by the projection of the gland, on either side of the frenulum linguae. One or more join to form the major sublingual duct (larger sublingual duct, duct of Bartholin), which opens into the submandibular duct. [WP,unvetted]." [Wikipedia:Sublingual_duct] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:59983 ! Sublingual duct xref: MA:0002699 ! sublingual duct xref: BTO:0004558 ! sublingual gland duct (also: UBERON:0003985 'major sublingual duct') intersection_of: UBERON:0001837 ! duct of salivary gland intersection_of: part_of UBERON:0001832 ! sublingual gland relationship: channels_from UBERON:0001832 ! sublingual gland xref: SCTID:281000009 ! Entire sublingual duct [Term] id: UBERON:0001349 name: vestibule def: "Anatomical cavity that connects an organ cavity, organ cavity subdivision or cavity of body part subdivision to the exterior, completely or partially surrounded by organs or organ parts that are lined by epithelium. Examples: preputial cavity, vestibule of vagina.[FMA]" [Wikipedia:Vestibule_(disambiguation)#Anatomy, FMA:20192, FMA:FMA] subset: uberon_slim xref: FMA:20192 ! Vestibule is_a: UBERON:0002553 ! anatomical cavity [Term] id: UBERON:0001846 name: internal ear def: "Complex labyrinthine structure that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation." [PMID:16217737, Wikipedia:Internal_ear, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "inner ear" EXACT [] synonym: "labyrinth" RELATED [] synonym: "otocyst" RELATED [] synonym: "auris interna" RELATED [BTO:0000630] xref: AAO:0000238 ! inner_ear xref: BTO:0000630 ! inner ear xref: EHDAA:504 ! inner ear xref: FMA:60909 ! Internal ear xref: galen:InnerEar xref: VHOG:0000284 ! inner ear xref: MA:0000237 ! inner ear xref: MAT:0000145 ! inner ear xref: MIAA:0000145 ! inner ear xref: NIF_GrossAnatomy:birnlex_1196 ! Inner ear xref: TAO:0000217 ! inner ear xref: XAO:0000192 ! inner ear xref: ZFA:0000217 ! inner ear xref: GAID:871 ! labyrinth xref: ncithesaurus:Internal_Ear ! Internal Ear xref: EFO:0001363 ! inner ear structure xref: EHDAA2:0000831 ! inner ear xref: EHDAA:504 ! inner ear xref: EMAPA:16194 ! inner ear xref: OpenCyc:Mx4rwJ8SsJwpEbGdrcN5Y29ycA ! inner ear xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/19/Gray923.png/200px-Gray923.png xref: MESH:A09.246.631 ! labyrinth xref: EV:0100361 ! internal ear is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001690 ! ear xref: SCTID:181189006 ! Entire inner ear relationship: develops_from UBERON:0003051 {evidence="definitional"} ! ear vesicle property_value: external_definition "The auditory (hearing) and vestibular (balance) organ of the fish, equivalent to the inner ear of amniotes. (See Anatomical Atlas entry for ear by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000217", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "The labyrinth, or inner ear, evolved very early in vertebrate history and, with many variations in configuration but none of basic design and function, has been retained by all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000284", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.366", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0022889 [Term] id: UBERON:0006937 name: inner ear epithelium xref: MA:0001189 ! inner ear epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001846 ! internal ear def: "An epithelium that is part of a internal ear." [OBOL:automatic] [Term] id: UBERON:0010113 name: future membranous labyrinth is_a: UBERON:0000481 ! multi-tissue structure relationship: develops_from UBERON:0005641 ! otocyst epithelium relationship: part_of UBERON:0004637 ! otic capsule relationship: part_of UBERON:0001846 ! internal ear intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: develops_into UBERON:0001849 ! membranous labyrinth xref: EHDAA2:0000899 ! future membranous labyrinth def: "A multi-tissue structure that develops_into a membranous labyrinth." [OBOL:automatic] [Term] id: UBERON:0001849 name: membranous labyrinth def: "Organ with organ cavity which consists of the vestibular labyrinth and the cochlear labyrinth. Examples: There are only two membranous labyrinths, the right and the left.[FMA]" [Wikipedia:Membranous_labyrinth, FMA:FMA] comment: inner ear has parts membranous and osseuous/bony labyrinth. it's not clear where the edinburgh terms 'labyrinth' belong, we place them here for now subset: uberon_slim xref: FMA:61022 ! Membranous labyrinth xref: VHOG:0000729 ! membranous labyrinth xref: MA:0000242 ! membranous labyrinth xref: XAO:0000194 ! membranous labyrinth xref: EHDAA:4698 ! labyrinth xref: EMAPA:17815 ! labyrinth xref: ncithesaurus:Membranous_Labyrinth ! Membranous Labyrinth xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray924.png/200px-Gray924.png xref: EV:0100367 ! membranous labyrinth is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001846 ! internal ear xref: AAO:0011060 ! membranous labyrinth xref: SCTID:263790009 ! Entire membranous labyrinth subset: organ_slim relationship: immediate_transformation_of UBERON:0010113 {evidence="definitional"} ! future membranous labyrinth synonym: "labyrinthus membranaceus" RELATED LATIN [Wikipedia:Membranous_labyrinth] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray924.png property_value: external_definition "A system of communicating epithelial sacs and ducts within the bony labyrinth, containing the endolymph. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000729", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/membranous+labyrinth", source="http://bgee.unil.ch/"} property_value: homology_notes "The labyrinth, or inner ear, evolved very early in vertebrate history and, with many variations in configuration but none of basic design and function, has been retained by all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000729", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.366", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0458700 [Term] id: UBERON:0001862 name: vestibular labyrinth def: "The part of the membranous labyrinth that includes the utricle and saccule lodged within the vestibule and the semicircular ducts lodged eccentrically in the corresponding canals." [BTO:0001856] synonym: "labyrinthus vestibularis" RELATED [BTO:0001856] synonym: "vestibular apparatus" RELATED [] synonym: "vestibular component" BROAD [] synonym: "inner ear vestibular component" EXACT [EHDAA2:0000832] xref: FMA:61255 ! Vestibular labyrinth xref: MA:0000245 ! vestibular labyrinth xref: ncithesaurus:Vestibular_Labyrinth ! Vestibular Labyrinth xref: BTO:0001856 ! vestibular labyrinth xref: EHDAA2:0000832 ! inner ear vestibular component xref: EHDAA:4706 ! vestibular component xref: EMAPA:17286 ! vestibular component of inner ear is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001849 ! membranous labyrinth xref: XAO:0004145 ! vestibular apparatus xref: SCTID:181188003 ! Vestibular apparatus (also: UBERON:0005236 'osseus labyrinth vestibule') xref: UMLS:C0042606 [Term] id: UBERON:0006586 ! otolymph name: otolymph xref: MA:0002527 ! otolymph xref: ncithesaurus:Otolymph ! otolymph is_a: UBERON:0007779 {source="FMA-abduced"} ! transudate relationship: part_of UBERON:0001846 ! internal ear xref: UMLS:C1518679 [Term] id: UBERON:0001845 name: perilymph def: "Transudate contained in the osseous labyrinth outside the membranous labyrinth.[FMA]" [Wikipedia:Perilymph, FMA:FMA] synonym: "perilympha" RELATED [Wikipedia:Perilymph] synonym: "liquor cotunnii" RELATED [Wikipedia:Perilymph] subset: uberon_slim subset: vertebrate_core xref: FMA:60908 ! Perilymph xref: GAID:1185 ! perilymph xref: MA:0002529 ! perilymph xref: ncithesaurus:Perilymph ! Perilymph xref: ZFA:0005413 ! perilymph xref: MESH:A12.207.571.678 ! perilymph is_a: UBERON:0006586 ! otolymph relationship: surrounds UBERON:0001849 {source="Wikipedia"} ! membranous labyrinth relationship: located_in UBERON:0001839 ! bony labyrinth relationship: located_in UBERON:0002278 ! perilymphatic space xref: TAO:0005413 ! perilymph xref: UMLS:C0031059 [Term] id: UBERON:0002278 ! perilymphatic space name: perilymphatic space def: "The fluid-filled space separating the membranous from the osseous labyrinth." [Dorlands_Medical_Dictionary:MerckSource] subset: vertebrate_core synonym: "Retzius space" RELATED [] synonym: "spatium perilymphaticum" RELATED [] xref: FMA:77745 ! Perilymphatic space xref: BTO:0002083 ! perilymphatic space xref: ZFA:0005459 ! perilymphatic space is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001846 ! internal ear relationship: surrounds UBERON:0001849 ! membranous labyrinth relationship: located_in UBERON:0001839 ! bony labyrinth xref: SCTID:362576001 ! Entire perilymphatic space [Term] id: UBERON:0011060 name: perilymphatic channel def: "A channel containing perilymph passing through the temporal bone, connecting the scala tympani of the cochlea to the subarachnoid space." [MESH:A09.246.631.246.280, Wikipedia:Perilymphatic_duct] comment: Editor notes: relationship to FMA class unclear synonym: "cochlear aqueduct" RELATED [MESH:A09.246.631.246.280, FMA:77822] synonym: "perilymphatic duct" RELATED [MESH:A09.246.631.246.280] synonym: "perilymphatic space" RELATED [MA:0000248] synonym: "ductus perilymphaticus" EXACT [AAO:0000136] is_a: UBERON:0000058 ! duct relationship: surrounds UBERON:0001845 ! perilymph relationship: part_of UBERON:0001846 {source="MA"} ! internal ear xref: AAO:0000136 ! ductus perilymphaticus xref: MA:0000248 ! perilymphatic channel xref: ZFA:0005461 ! perilymphatic duct xref: SCTID:368950002 ! Entire perilymphatic duct xref: FMA:77822 ! Cochlear aqueduct [Term] id: UBERON:0001852 ! endolymph name: endolymph def: "Transudate contained within the membranous labyrinth.[FMA]" [Wikipedia:Endolymph, FMA:61112] synonym: "Scarpa's fluid" RELATED [Wikipedia:Endolymph] synonym: "endolympha" RELATED [Wikipedia:Endolymph] synonym: "endolymphatic fluid" EXACT [] subset: uberon_slim subset: vertebrate_core xref: FMA:61112 ! Endolymph xref: GAID:1184 ! endolymph xref: MA:0002528 ! endolymph xref: ncithesaurus:Endolymph ! Endolymph xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Cochlea-crosssection.png/200px-Cochlea-crosssection.png xref: ZFA:0005414 ! endolymph xref: MESH:A12.207.571.324 ! endolymph is_a: UBERON:0006586 ! otolymph relationship: located_in UBERON:0001849 {source="Wikipedia"} ! membranous labyrinth relationship: has_function_in GO:0055127 ! vibrational conductance of sound to the inner ear xref: TAO:0005414 ! endolymph synonym: "endolympha" RELATED LATIN [Wikipedia:Endolymph] xref: http://upload.wikimedia.org/wikipedia/commons/c/c7/Cochlea-crosssection.png xref: UMLS:C0014166 property_value: has_relational_adjective "otolymphic" xsd:string [Term] id: UBERON:0011078 name: endolymphatic space xref: FMA:77823 ! endolymphatic space xref: SCTID:279856000 ! Endolymphatic space is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001846 ! internal ear relationship: located_in UBERON:0001849 {source="Wikipedia"} ! membranous labyrinth property_value: has_relational_adjective "endoymphatic" xsd:string [Term] id: UBERON:0001860 name: endolymphatic duct def: "From the posterior wall of the saccule a canal, the endolymphatic duct, is given off; this duct is joined by the ductus utriculosaccularis, and then passes along the aquaeductus vestibuli and ends in a blind pouch on the posterior surface of the petrous portion of the temporal bone, where it is in contact with the dura mater. [WP,unvetted]." [Wikipedia:Endolymphatic_duct] subset: uberon_slim subset: vertebrate_core synonym: "ductus endolymphaticus" EXACT LATIN [AAO:0000135] xref: FMA:61246 ! Endolymphatic duct xref: GAID:886 ! endolymphatic duct xref: MA:0001187 ! endolymphatic duct xref: ZFA:0001705 ! endolymphatic duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/Gray924.png/200px-Gray924.png xref: EMAPA:18580 ! endolymphatic duct xref: MESH:A09.246.631.909.957.360 ! endolymphatic duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0001849 ! membranous labyrinth xref: SCTID:362567008 ! Entire endolymphatic duct xref: TAO:0002194 ! endolymphatic duct xref: AAO:0000135 ! ductus endolymphaticus synonym: "ductus endolymphaticus" RELATED LATIN [Wikipedia:Endolymphatic_duct] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray924.png property_value: external_definition "Duct that is part of the inner ear and connects to the semicircular canals ending in a pouch.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002194", date_retrieved="2012-08-14", source="http:en.wikipedia.org/wiki/Endolymphatic_duct"} property_value: has_relational_adjective "endoymphatic" xsd:string [Term] id: UBERON:0002223 name: endolymphatic sac def: "From the posterior wall of the saccule a canal, the ductus endolymphaticus, is given off; this duct is joined by the ductus utriculosaccularis, and then passes along the aquaeductus vestibuli and ends in a blind pouch, the endolymphatic sac, on the posterior surface of the petrous portion of the temporal bone, where it is in contact with the dura mater. Studies suggest that the endolymphatic duct and endolymphatic sac perform both absorptive and secretory, as well as phagocytic and immunodefensive,functions . [WP,unvetted]." [Wikipedia:Endolymphatic_sac] comment: Editor's note: EHDAA2 structure is embryonic subset: uberon_slim synonym: "saccus endolymphaticus" EXACT [AAO:0000551] xref: EHDAA:7761 ! endolymphatic sac xref: FMA:75639 ! Endolymphatic sac xref: GAID:887 ! endolymphatic sac xref: VHOG:0000791 ! endolymphatic sac xref: MA:0001188 ! endolymphatic sac xref: EHDAA2:0000441 ! endolymphatic sac xref: EMAPA:17593 ! endolymphatic sac xref: MESH:A09.246.631.909.957.360.701 ! endolymphatic sac is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: part_of UBERON:0001846 {source="VHOG"} ! internal ear relationship: develops_from UBERON:0006226 {source="EHDAA2"} ! endolymphatic appendage xref: SCTID:279810008 ! Entire endolymphatic sac xref: AAO:0000551 ! saccus endolymphaticus synonym: "saccus endolymphaticus" RELATED LATIN [Wikipedia:Endolymphatic_sac] property_value: external_definition "The blind extremity of the endolymphatic duct. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000791", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/endolymphatic+sac", source="http://bgee.unil.ch/"} property_value: homology_notes "Many adult anamniotes have an endolymphatic duct that opens onto the surface of the head. In other vertebrates, it either is lost or forms a small, deeply seated endolymphatic sac.[well established][VHOG]" xsd:string {external_class="VHOG:0000791", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413-414 and Figure 12-15", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001839 name: bony labyrinth def: "A system of fluid passages in the inner ear, including both the cochlea, which is part of the auditory system, and the vestibular system, which provides the sense of balance. The bony labyrinth, or osseous labyrinth, is the network of passages with bony walls lined with periosteum. The bony labyrinth is lined with the membranous labyrinth. There is a layer of perilymph between them. The three parts of the bony labyrinth are the vestibule of the ear, the semicircular canals, and the cochlea. The vestibular system is the region of the inner ear where the semicircular canals converge, close to the cochlea (the hearing organ). The vestibular system works with the visual system to keep objects in focus when the head is moving. Joint and muscle receptors also are important in maintaining balance. The brain receives, interprets, and processes the information from these systems that control our balance. [WP,unvetted]." [Wikipedia:Bony_labyrinth] comment: Ideally we would place a spatially disjoint from relationship to membranous labyrinth, but there are many parts in common. this should be resolved. subset: uberon_slim synonym: "osseous labyrinth" EXACT [] synonym: "osseus labyrinth" RELATED [] xref: FMA:60179 ! Bony labyrinth xref: MA:0000238 ! bony labyrinth xref: XAO:0000193 ! osseous labyrinth xref: ncithesaurus:Osseous_Labyrinth ! Osseous Labyrinth xref: VHOG:0001219 ! osseus labyrinth xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/22/Gray920.png/200px-Gray920.png xref: BTO:0004685 ! bony labyrinth xref: EV:0100362 ! osseous labyrinth is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001694 ! petrous part of temporal bone relationship: part_of UBERON:0001846 ! internal ear relationship: part_of UBERON:0004681 ! vestibular system xref: AAO:0011078 ! osseous labyrinth xref: SCTID:279727008 ! Entire bony labyrinth synonym: "labyrinthus osseus" RELATED LATIN [Wikipedia:Bony_labyrinth] xref: http://upload.wikimedia.org/wikipedia/commons/2/22/Gray920.png xref: UMLS:C0458699 [Term] id: UBERON:0005236 name: osseus labyrinth vestibule def: "A small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear." [Wikipedia:Vestibule_of_the_ear, BTO:0003382] synonym: "vestibular apparatus" RELATED [GAID:881] synonym: "vestibule" BROAD [XAO:0000199, MP:0000034] synonym: "inner ear vestibule" RELATED [BTO:0003382] synonym: "inner ear vestibulum" EXACT [BTO:0003382] synonym: "bony labyrinth vestibule" EXACT [] synonym: "vestibule of bony labyrinth" EXACT [FMA:60183] synonym: "osseous labyrinth vestibule" EXACT [OBOL:automatic] xref: VHOG:0001220 xref: GAID:881 ! vestibule xref: XAO:0000199 ! vestibule xref: MA:0001185 ! osseus labyrinth vestibule xref: BTO:0003382 ! inner ear vestibulum xref: ncithesaurus:Vestibule ! Vestibule xref: FMA:60183 ! Vestibule of bony labyrinth xref: MESH:A09.246.631.909 ! vestibule xref: EV:0100366 ! vestibule is_a: UBERON:0000064 ! organ part disjoint_from: UBERON:0001349 relationship: part_of UBERON:0001839 ! bony labyrinth xref: AAO:0000984 ! vestibule xref: SCTID:181188003 ! Vestibular apparatus (also: UBERON:0001862 'vestibular labyrinth') synonym: "vestibulum labyrinthi, vestibulum auris" RELATED LATIN [Wikipedia:Vestibule_of_the_ear] xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray919.png property_value: external_definition "A tube leading from the external naris to the nasal cavity.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000984", date_retrieved="2012-06-20", source="AAO:EJS"} synonym: "vestibular part of bony labyrinth" RELATED [FMA:60183] property_value: external_definition "The vestibule is the central part of the osseous labyrinth, and is situated medial to the tympanic cavity, behind the cochlea, and in front of the semicircular canals. [http://en.wikipedia.org/wiki/Vestibule_of_the_ear][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001220", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0458718 [Term] id: UBERON:0002518 name: otolith organ def: "saccule or utricle." [Wikipedia:Otolith_organ] comment: Editor notes: Representation of utricle, sacule and otoliths in correspondence to other ontologies may require review. In EHDAA2, saccule and utricle are epithelia subset: uberon_slim subset: vertebrate_core synonym: "otolith organs" RELATED [ZFA:0000559] synonym: "utricle and saccule" RELATED [MESH:A09.246.631.909.625] synonym: "saccule and utricle" RELATED [MESH:A09.246.631.909.625] xref: MESH:A09.246.631.909.625 ! saccule and utricle xref: MA:0002841 ! otolith organ xref: ZFA:0000559 ! otolith organ xref: GAID:883 ! saccule and utricle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Bigotolith.jpg/200px-Bigotolith.jpg xref: EFO:0003539 ! otolith organ is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001862 ! vestibular labyrinth relationship: has_function_in GO:0060007 ! linear vestibuloocular reflex relationship: develops_from UBERON:0003051 ! ear vesicle subset: organ_slim xref: TAO:0000559 ! otolith organ xref: VHOG:0001676 ! otolith organ xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Bigotolith.jpg property_value: homology_notes "In fishes, as in other vertebrates, the vestibular end-organs are divided into a gravity receptor system, with three subdivisions and an angular acceleration receptor system. The gravity receptor system on each side consists of utricular, saccular, and lagenar maculae, each covered by an otolith (reference 1); (...)considerations have led to our rethinking issues related to the origin of several aspects of vertebrate hearing, and to the view that many basic auditory functions evolved very early in vertebrate history, and that the functions observed in more `advanced' vertebrates, such as birds and mammals, are frequently modifications of themes first encountered in fishes, and perhaps even more ancestral animals (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001676", ontology="VHOG", source="PMID:11581521 Moorman SJ\, Development of sensory systems in zebrafish (Danio rerio). ILAR Journal (2001)\, DOI:10.1016/S0378-5955(00)00168-4 Fay RR\, Popper AN\, Evolution of hearing in vertebrates: the inner ears and processing. Hearing research (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001853 name: utricle of membranous labyrinth def: "one of the two otolith organs located in the vertebrate inner ear. These use small stones and a viscous fluid to stimulate hair cells to detect motion and orientation. The utricle is larger than the saccule and is of an oblong form, compressed transversely, and occupies the upper and back part of the vestibule, lying in contact with the recessus ellipticus and the part below it. The utricle contains mechanoreceptors called hair cells that distinguish between degrees of tilting of the head, thanks to their apical cilia set-up. These are covered by otolith which, due to gravity, pull on the cilia and tilt them. Depending on whether the tilt is in the direction of the kinocilium or not, the resulting hair cell polarisation is excitatory (depolarising) or inhibitory (hyperpolarisation), respectively. This signal to the vestibular nerve (which takes it to the brainstem) does not adapt with time. The effect of this is that, for example, an individual lying down to sleep will continue to detect that they are lying down hours later when they awaken[WP]." [Wikipedia:Utricle_(ear)] comment: XAO/AAO to be checked - see https://github.com/seger/aao/issues/5; AAO has both utricle and utriculus; these are generally considered synonyms - e.g. http://www.fishbase.org/glossary/Glossary.php?q=utriculus subset: uberon_slim subset: vertebrate_core synonym: "membranous labyrinth utricle" EXACT [] synonym: "utricle" EXACT [] synonym: "utriculus (labyrinthus vestibularis)" EXACT [] synonym: "utriculus" EXACT [ZFA:0000700] xref: EHDAA:4726 ! utricle xref: FMA:61113 ! Utricle of membranous labyrinth xref: VHOG:0000289 ! utricle xref: MA:0000247 ! utricle xref: TAO:0000700 ! utricle xref: XAO:0000195 ! utricle xref: ZFA:0000700 ! utricle xref: ncithesaurus:Utricle ! Utricle xref: BTO:0001807 ! utricle xref: EHDAA2:0002153 ! utricle xref: EMAPA:17293 ! utricle xref: AAO:0000625 ! utriculus xref: AAO:0011109 ! utricle xref: EV:0100368 ! utricle is_a: UBERON:0002518 {source="ZFA", source="Wikipedia"} ! otolith organ xref: SCTID:279817006 ! Entire utricle subset: organ_slim property_value: external_definition "The portion of the membranous labyrinth of the ear into which the semicircular ducts find their outlet. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000289", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus.[well established][VHOG]" xsd:string {external_class="VHOG:0000289", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413-414", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0042158 [Term] id: UBERON:0001854 name: saccule of membranous labyrinth def: "A bed of sensory cells situated in the inner ear. The saccule translates head movements into neural impulses which the brain can interpret. The saccule is sensitive to linear translations of the head, specifically movements up and down (think about moving on an elevator). When the head moves vertically, the sensory cells of the saccule are disturbed and the neurons connected to them begin transmitting impulses to the brain. These impulses travel along the vestibular portion of the eighth cranial nerve to the vestibular nuclei in the brainstem. is the smaller of the two vestibular sacs. It is globular in form and lies in the recessus sphæricus near the opening of the scala vestibuli of the cochlea. Its cavity does not directly communicate with that of the utricle. The anterior part of the saccule exhibits an oval thickening, the macula acustica sacculi, or macula, to which are distributed the saccular filaments of the vestibular branch of the vestibulocochlear nerve, also known as the acoustic nerve or cranial nerve VIII[WP]." [Wikipedia:Saccule] comment: XAO/AAO to be checked - see https://github.com/seger/aao/issues/5 subset: uberon_slim subset: vertebrate_core synonym: "membranous labyrinth saccule" EXACT [] synonym: "saccule" EXACT [] synonym: "sacculus (labyrinthus vestibularis)" EXACT [] synonym: "sacculus" EXACT [ZFA:0000428] xref: EHDAA:4712 ! saccule xref: FMA:61116 ! Saccule of membranous labyrinth xref: VHOG:0000374 ! saccule xref: MA:0000246 ! saccule xref: TAO:0000428 ! saccule xref: ZFA:0000428 ! saccule xref: ncithesaurus:Saccule ! Saccule xref: BTO:0001805 ! saccule xref: EHDAA2:0001769 ! saccule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Bigotolith.jpg/200px-Bigotolith.jpg xref: XAO:0000196 ! sacculus xref: EMAPA:17290 ! saccule xref: AAO:0000550 ! sacculus xref: EV:0100369 ! saccule is_a: UBERON:0002518 {source="ZFA", source="Wikipedia"} ! otolith organ xref: SCTID:279827000 ! Entire saccule subset: organ_slim synonym: "sacculus" RELATED LATIN [Wikipedia:Saccule] xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Bigotolith.jpg property_value: external_definition "The most ventral chamber of the membranous labyrinth. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-25, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000374", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus. (...) In all gnathostomes, the utriculus connects ventrally with a larger sac, called the sacculus (...) .[well established][VHOG]" xsd:string {external_class="VHOG:0000374", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413-414", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0036029 [Term] id: UBERON:0011774 ! utriculosaccular duct name: utriculosaccular duct def: "A duct connecting the the utricle to the saccule in the membranous labyrinth of the ear." [http://www.merriam-webster.com/medical/utriculosaccular%20duct] comment: Alternate: leads from the utricle of the internal ear to the endolymphatic duct. - http://medical-dictionary.thefreedictionary.com/utriculosaccular+duct. We assume a 3-way connection synonym: "ductus utricosaccularis" EXACT [FMA:61243] synonym: "utricosaccular duct of membranous labyrinth" EXACT [FMA:61243] synonym: "Böttcher's canal" EXACT [http://en.wikipedia.org] synonym: "utricosaccular duct" EXACT [] synonym: "utriculo-saccular duct" EXACT [] xref: FMA:61243 ! utriculosaccular duct xref: SCTID:279811007 ! Entire utriculosaccular duct intersection_of: UBERON:0000058 ! duct intersection_of: connects UBERON:0001853 ! utricle of membranous labyrinth intersection_of: connects UBERON:0001854 ! saccule of membranous labyrinth intersection_of: connects UBERON:0001860 ! endolymphatic duct relationship: part_of UBERON:0001862 {source="MP"} ! vestibular labyrinth [Term] id: UBERON:0003976 name: saccule duct def: "the saccular portion of the utriculosaccular duct that normally extends from the sacculus to the endolymphatic duct" [MP:0009259] synonym: "saccular duct" EXACT [MP:0009259] synonym: "saccular part of utriculosaccular duct" EXACT [] is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0011774 ! utriculosaccular duct relationship: connects UBERON:0001854 ! saccule of membranous labyrinth relationship: connects UBERON:0001860 ! endolymphatic duct xref: FMA:77825 ! saccular duct xref: SCTID:279829002 ! Saccular opening of the utriculosaccular duct [Term] id: UBERON:0003977 name: utricle duct def: "the utricular portion of the utriculosaccular duct that normally extends from the utriculus to the endolymphatic duct" [MP:0009260] synonym: "utricular duct" EXACT [MP:0009260] synonym: "utricular part of utriculosaccular duct" EXACT [] is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0011774 ! utriculosaccular duct relationship: connects UBERON:0001853 ! utricle of membranous labyrinth relationship: connects UBERON:0001860 ! endolymphatic duct xref: FMA:77824 ! utricular duct xref: SCTID:279819009 ! Utricular opening of the utriculosaccular duct [Term] id: UBERON:0001861 name: ductus reuniens def: "The canalis reuniens of Hansen is part of the human inner ear. It connects the lower part of the saccule to the ductus cochlearis near its vestibular extremity." [Wikipedia:Canalis_reuniens_of_Hensen] synonym: "canal of Henson" RELATED [Wikipedia:Canalis_reuniens_of_Hensen] synonym: "canalis reuniens" RELATED [Wikipedia:Canalis_reuniens_of_Hensen] synonym: "canalis reuniens of Hensen" RELATED [Wikipedia:Canalis_reuniens_of_Hensen] synonym: "Hensen duct" RELATED [Wikipedia:Canalis_reuniens_of_Hensen] synonym: "Hensen's duct" RELATED [Wikipedia:Canalis_reuniens_of_Hensen] xref: FMA:61252 ! Ductus reuniens xref: MA:0000244 ! ductus reuniens xref: EMAPA:17287 ! ductus reuniens is_a: UBERON:0000058 ! duct relationship: connects UBERON:0001854 {source="Wikipedia"} ! saccule of membranous labyrinth relationship: connects UBERON:0001855 {source="Wikipedia"} ! cochlear duct of membranous labyrinth relationship: part_of UBERON:0001862 {source="EMAPA"} ! vestibular labyrinth xref: SCTID:279805009 ! Entire ductus reuniens [Term] id: UBERON:0002519 name: otolithic membrane def: "a gelatinous membrane located in the vestibular apparatus of the inner ear, and plays an essential role in the brain's interpretation of equilibrium. Both the saccular macula and utricular macula are covered by an otolithic membrane. The membrane is composed of crystalline particles of calcium carbonate called otoliths. When the head is moved the otoliths shift, causing cilia in the nearby saccule and utricle to distort. This produces nerve signals which are sent to the brain, which then uses them to establish its sense of balance. The embedded crystals are very and dense and make the density of the otolithic membrane higher than that of the endolymph surrounding it. When the head accelerates along a line or tilts to change its orientation to gravity, the otolithic membrane shifts relative to the bone supporting the maculae. This shift bends the hair cells whose processes are embedded in the otolithic membrane.[WP]." [Wikipedia:Otolithic_membrane] subset: uberon_slim synonym: "otolith layer of statoconial membrane" EXACT [FMA:75573] synonym: "membrana statoconiorum" EXACT LATIN [FMA:TA, FMA:75573] xref: FMA:75573 ! Otolith layer of statoconial membrane xref: MA:0002842 ! otolithic membrane xref: GAID:884 ! otolithic membrane xref: MESH:A09.246.631.909.625.125.680 ! otolithic membrane is_a: UBERON:0005764 {source="Wikipedia"} ! acellular membrane relationship: part_of UBERON:0001862 {source="MA"} ! vestibular labyrinth relationship: surrounds UBERON:0002518 {source="Wikipedia"} ! otolith organ xref: SCTID:362571006 ! Entire otolithic membrane [Term] id: UBERON:0001840 name: semicircular canal def: "One of three half-circular, interconnected tubes located inside each ear[WP]. Fluid-filled toroidal spaces, arranged orthogonally to each other in the ear, that detect angular accelerations. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)" [Wikipedia:Semicircular_canal, ZFIN:curator] comment: Note that MA divides this into osseous and duct. In FMA, this is systemically part of the bony labyrinth. Note this is an anatomical space in ZFA. The MA treatment has advantages for representing the neuroepithelium, which should not be part of bone. Also check duct vs canal subset: uberon_slim subset: vertebrate_core synonym: "canalis semicircularis" RELATED [] synonym: "ductus semicirculares" RELATED PLURAL [FMA:TA, FMA:71880, BTO:0003383] xref: FMA:60186 ! Semicircular canal xref: GAID:776 ! semicircular canal xref: VHOG:0001144 ! semicircular canal xref: MA:0000249 ! semicircular canal xref: TAO:0000431 ! semicircular canal xref: XAO:0000198 ! semicircular canal xref: ZFA:0000431 ! semicircular canal xref: ncithesaurus:Semicircular_Canal ! Semicircular Canal xref: BTO:0003383 ! semicircular canal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Balance_Disorder_Illustration_A.png/200px-Balance_Disorder_Illustration_A.png xref: MESH:A09.246.631.663 ! semicircular canal xref: EV:0100365 ! semicircular canal is_a: UBERON:0000025 {source="GO"} ! tube relationship: part_of UBERON:0001849 {source="OG"} ! membranous labyrinth relationship: part_of UBERON:0001846 {source="MA"} ! internal ear relationship: develops_from UBERON:0003051 ! ear vesicle xref: AAO:0011098 ! semicircular canal xref: SCTID:279757004 ! Entire semicircular canal synonym: "canalis semicircularis" RELATED LATIN [Wikipedia:Semicircular_canal] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Balance_Disorder_Illustration_A.png property_value: external_definition "Fluid-filled toroidal spaces, arranged orthogonally to each other in the ear, that detect angular accelerations. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000431", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "scc" RELATED [TAO:0000431] synonym: "semicircular canals" EXACT PLURAL [TAO:0000431] property_value: homology_notes "In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus. These ducts are sometimes called canals, but technically the term semicircular canal applies to the spaces in the osseus labyrinth in which the semicircular ducts lie.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001144", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.414", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0036622 [Term] id: UBERON:0007833 name: osseus semicircular canal comment: consider adding FMA:60186 ! Semicircular canal here, as it is part of the bony labyrinth synonym: "osseous semicircular canal" EXACT [OBOL:automatic] xref: MA:0000250 ! osseus semicircular canal is_a: UBERON:0005913 {notes="checkme"} ! zone of bone organ relationship: part_of UBERON:0001839 {source="MA"} ! bony labyrinth relationship: part_of UBERON:0001840 {source="MA"} ! semicircular canal [Term] id: UBERON:0001856 name: semicircular duct def: "any of the three loop-shaped membranous inner tubular parts of the semicircular canals that are about one-fourth the diameter of the corresponding outer bony canals, that communicate at each end with the utricle, and that have near one end an expanded ampulla containing an area of sensory epithelium" [http://dictionary.reference.com/browse/semicircular+duct] comment: TODO - check canal vs duct. see http://en.wikipedia.org/wiki/File:Gray927.png synonym: "membranous semicircular canal" RELATED [MA:0000251] synonym: "ductus semicirculares" RELATED PLURAL [FMA:TA, FMA:71880] xref: FMA:61122 ! Semicircular duct xref: VHOG:0000238 ! semicircular duct xref: MA:0000251 ! semicircular duct xref: ncithesaurus:Semicircular_Duct ! Semicircular Duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0001862 {source="MA", source="FMA"} ! vestibular labyrinth relationship: part_of UBERON:0001840 {source="MA"} ! semicircular canal xref: SCTID:279833009 ! Entire semicircular duct property_value: homology_notes "In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus (...); Gnathostome ears have a horizontal semicircular duct. This brings their complement to three semicircular ducts, a pattern retained throughout gnathostome evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0000238", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413-414 and p.58", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1323109 [Term] id: UBERON:0001857 name: anterior semicircular duct comment: This class was created automatically from a combination of ontologies xref: FMA:61123 ! Anterior semicircular duct xref: VHOG:0000246 ! anterior semicircular duct xref: MA:0001211 ! anterior semicircular duct is_a: UBERON:0001856 ! semicircular duct relationship: part_of UBERON:0001841 ! anterior semicircular canal xref: SCTID:279836001 ! Entire anterior semicircular duct synonym: "superior semicircular duct" RELATED [VHOG:0000246] property_value: homology_notes "Vertebrata is characterized by three synapomorphies. (...) Vertebrates also have at least two vertical semicircular ducts (...). In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus.[well established][VHOG]" xsd:string {external_class="VHOG:0000246", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.53 and p.413-414", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001858 name: posterior semicircular duct def: "The semicircular canals are three half-circular, interconnected tubes located inside each ear. The three canals are the horizontal semicircular canal (also known as the lateral semicircular canal), superior semicircular canal (also known as the anterior semicircular canal), and the posterior semicircular canal. The canals are aligned approximately orthogonally to one another. The horizontal canal is aligned roughly horizontally in the head. The superior and anterior canals are aligned roughly at a 45 degree angle to a vertical plane drawn from the nose to the back of the skull. Thus, the horizontal canal detects horizontal head movements (such as when doing a pirouette), while the superior and posterior canals detect vertical head movements. Each canal is filled with a fluid called endolymph and contains a motion sensor with little hairs whose ends are embedded in a gelatinous structure called the cupula. As the skull twists in any direction, the endolymph is thrown into different sections of the canals. The cilia detect when the endolymph rushes past, and a signal is then sent to the brain. The semicircular canals are a component of the Labyrinth. Among species of mammals, the size of the semicircular canals is correlated with their type of locomotion. Specifically, species that are agile and have fast, jerky locomotion have larger canals relative to their body size than those that move more cautiously. [WP,unvetted]." [Wikipedia:Semicircular_canal] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:61126 ! Posterior semicircular duct xref: VHOG:0000248 ! posterior semicircular duct xref: MA:0001214 ! posterior semicircular duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Balance_Disorder_Illustration_A.png/200px-Balance_Disorder_Illustration_A.png is_a: UBERON:0001856 ! semicircular duct relationship: part_of UBERON:0001842 ! posterior semicircular canal xref: SCTID:279835002 ! Entire posterior semicircular duct property_value: homology_notes "Vertebrata is characterized by three synapomorphies. (...) Vertebrates also have at least two vertical semicircular ducts (...). In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus.[well established][VHOG]" xsd:string {external_class="VHOG:0000248", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.53 and p.413-414", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001859 name: lateral semicircular duct def: "The lateral or horizontal canal (external semicircular canal) is the shortest of the three canals. Movement of fluid within this canal corresponds to rotation of the head around a vertical axis (i.e. the neck). [WP,unvetted]." [Wikipedia:Lateral_semicircular_duct] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:61129 ! Lateral semicircular duct xref: VHOG:0000247 ! lateral semicircular duct xref: MA:0001213 ! lateral semicircular duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray921.png/200px-Gray921.png is_a: UBERON:0001856 ! semicircular duct relationship: part_of UBERON:0001843 ! lateral semicircular canal xref: SCTID:279834003 ! Entire lateral semicircular duct property_value: homology_notes "Gnathostome ears have a horizontal semicircular duct. This brings their complement to three semicircular ducts, a pattern retained throughout gnathostome evolution. [ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.58] ; In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus.[well established][VHOG]" xsd:string {external_class="VHOG:0000247", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413-414", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001841 ! anterior semicircular canal name: anterior semicircular canal def: "One of three fluid-filled toroidal spaces, arranged orthogonally to each other in each ear, that detect angular acceleration. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)" [Wikipedia:Anterior_semicircular_canal, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "anterior semicircular canals" RELATED [] synonym: "anterior semicircular duct" RELATED [] synonym: "rostral vertical semicircular canal" RELATED [] synonym: "superior semicircular canal" EXACT [] synonym: "canalis semircularis posterior" RELATED [AAO:0000058] xref: EHDAA:7802 ! superior semicircular canal xref: FMA:60187 ! Anterior semicircular canal xref: MA:0001207 ! anterior semicircular canal xref: TAO:0000314 ! anterior semicircular canal xref: ZFA:0000314 ! anterior semicircular canal xref: ncithesaurus:Superior_Semicircular_Canal ! Superior Semicircular Canal xref: EHDAA2:0001959 ! superior semicircular canal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray921.png/200px-Gray921.png xref: EMAPA:17299 ! superior semicircular canal is_a: UBERON:0001840 ! semicircular canal relationship: part_of UBERON:0001840 ! semicircular canal xref: SCTID:279764002 ! Entire anterior semicircular canal xref: AAO:0000058 ! canalis semircularis posterior property_value: external_definition "One of three fluid-filled toroidal spaces, arranged orthogonally to each other in each ear, that detect angular acceleration. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000314", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from anterior semicircular canal primordium (TAO:0000469)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000314", date_retrieved="2012-08-14"} xref: UMLS:C1288332 [Term] id: UBERON:0001842 ! posterior semicircular canal name: posterior semicircular canal def: "One of three fluid-filled toroidal spaces, arranged orthogonally to each other in each ear, that detect angular acceleration. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)" [Wikipedia:Posterior_semicircular_canal, ZFIN:curator] comment: Editor notes: verify AAO subset: uberon_slim subset: vertebrate_core synonym: "caudal vertical semicircular canal" RELATED [] synonym: "posterior semicircular canals" RELATED [] synonym: "posterior semicircular duct" RELATED [] synonym: "pars superior of labyrinth" RELATED [AAO:0000420] xref: EHDAA:7796 ! posterior semicircular canal xref: FMA:60190 ! Posterior semicircular canal xref: MA:0001209 ! posterior semicircular canal xref: TAO:0000262 ! posterior semicircular canal xref: ZFA:0000262 ! posterior semicircular canal xref: ncithesaurus:Posterior_Semicircular_Canal ! Posterior Semicircular Canal xref: EHDAA2:0001489 ! posterior semicircular canal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray921.png/200px-Gray921.png xref: EMAPA:17296 ! posterior semicircular canal is_a: UBERON:0001840 ! semicircular canal relationship: part_of UBERON:0001840 ! semicircular canal xref: SCTID:279762003 ! Entire posterior semicircular canal xref: AAO:0000420 ! pars superior of labyrinth synonym: "canalis semicircularis posterior" RELATED LATIN [Wikipedia:Posterior_semicircular_canal] xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray921.png property_value: external_definition "One of three fluid-filled toroidal spaces, arranged orthogonally to each other in each ear, that detect angular acceleration. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000262", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from posterior semicircular canal primordium (TAO:0000412)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000262", date_retrieved="2012-08-14"} xref: UMLS:C0229454 [Term] id: UBERON:0001843 ! lateral semicircular canal name: lateral semicircular canal def: "One of three fluid-filled toroidal spaces, arranged orthogonally to each other in each ear, that detect angular acceleration. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)" [Wikipedia:Lateral_semicircular_canal, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "horizontal semicircular canal" RELATED [] synonym: "lateral semicircular canals" RELATED [] synonym: "lateral semicircular duct" RELATED [] xref: EHDAA:7790 ! lateral semicircular canal xref: FMA:60193 ! Lateral semicircular canal xref: MA:0001208 ! lateral semicircular canal xref: TAO:0000220 ! lateral semicircular canal xref: ZFA:0000220 ! lateral semicircular canal xref: EHDAA2:0000920 ! lateral semicircular canal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray921.png/200px-Gray921.png xref: EMAPA:17821 ! lateral semicircular canal is_a: UBERON:0001840 ! semicircular canal relationship: part_of UBERON:0001840 ! semicircular canal xref: SCTID:279761005 ! Entire lateral semicircular canal property_value: external_definition "One of three fluid-filled toroidal spaces, arranged orthogonally to each other in each ear, that detect angular acceleration. (See Anatomical Atlas entry for semicircular canals by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000220", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from lateral semicircular canal primordium (TAO:0000232)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000220", date_retrieved="2012-08-14"} [Term] id: UBERON:0001855 name: cochlear duct of membranous labyrinth def: "An endolymph filled cavity inside the cochlea, located in between the scala tympani and the scala vestibuli, separated by the basilar membrane and Reissner's membrane (the vestibular membrane) respectively. Houses the organ of Corti[WP]." [Wikipedia:Cochlear_duct] comment: TODO: check cochlear duct vs cochlear aqueduct vs scala media subset: uberon_slim synonym: "scala media" RELATED [Wikipedia:Cochlear_duct] synonym: "cochlear duct" EXACT [] synonym: "cochlear aqueduct" RELATED [] synonym: "Reissner's canal" EXACT [] synonym: "cochlea duct" EXACT [NIF_GrossAnatomy:birnlex_2562] synonym: "reissners canal" EXACT [NIF_GrossAnatomy:birnlex_2562] synonym: "scala medias" EXACT [NIF_GrossAnatomy:birnlex_2562] synonym: "ductus cochlearis" RELATED [BTO:0001692] synonym: "membranous cochlea" RELATED [BTO:0001692] synonym: "scala of Loewenberg" RELATED [BTO:0001692] xref: EHDAA:4718 ! cochlear duct xref: FMA:61119 ! Cochlear duct of membranous labyrinth xref: GAID:874 ! cochlear duct xref: VHOG:0000507 ! cochlear duct xref: MA:0000243 ! cochlear duct xref: NIF_GrossAnatomy:birnlex_2562 ! Cochlea duct xref: ncithesaurus:Cochlear_Duct ! Cochlear Duct xref: BTO:0001692 ! cochlear duct xref: EMAPA:17598 ! cochlear duct xref: NIF_GrossAnatomy:birnlex_2562 ! Cochlea duct xref: EHDAA2:0000262 ! cochlear duct (also: UBERON:0002295 'scala media') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bc/Gray928.png/200px-Gray928.png xref: MESH:A09.246.631.246.292 ! cochlear duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0001844 ! cochlea relationship: part_of UBERON:0001849 ! membranous labyrinth relationship: part_of UBERON:0002499 ! cochlear labyrinth xref: SCTID:279849006 ! Entire cochlear duct synonym: "ductus cochlearis" RELATED LATIN [Wikipedia:Cochlear_duct] xref: http://upload.wikimedia.org/wikipedia/commons/b/bc/Gray928.png property_value: external_definition "The coiled portion of the membranous labyrinth located inside the cochlea. It contains endolymph. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000507", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/cochlear+duct", source="http://bgee.unil.ch/"} property_value: homology_notes "In gnathostomes, each membranous labyrinth has three semicircular ducts that connect with a chamber known as the utriculus. (...) In all gnathostomes, the utriculus connects ventrally with a larger sac, called the sacculus (...) In most groups of gnathostomes, the caudoventral evagination of the sacculus forms a small lagena, and in some diapsids and mammals the lagena develops into a longer duct. The lagena becomes greatly elongated in therians and coils to form the cochlear duct.[well established][VHOG]" xsd:string {external_class="VHOG:0000507", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413-414", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1323110 [Term] id: UBERON:0001844 name: cochlea def: "The cochlea is the auditory portion of the inner ear. Its core component is the Organ of Corti, the sensory organ of hearing, which is distributed along the partition separating fluid chambers in the coiled tapered tube of the cochlea. The name is from the Latin for snail, which is from the Greek kokhlias 'snail, screw,' from kokhlos 'spiral shell,' in reference to its coiled shape; the cochlea is coiled in most mammals, monotremes being the exceptions. [WP,unvetted]." [Wikipedia:Cochlea] comment: AO notes: sources vary in connection to bony labyrinth. Taxon notes: The association with 'lagena' in frog and fish comes from HOG, although HOG is inconsistent here, associating lagena with XAO cochlea and ZFA cochlear duct. NBK53175 says: "In contrast, the ventrally located auditory chambers have undergone more extensive evolutionary modifications. The saccule and lagena are prominent auditory organs in fish but the saccule has a vestibular role in mammals and birds, and the lagena is absent in mammals. The primary au- ditory organ in mammals and birds is the cochlea, which has no known counterpart in amphibians and fish (Riley and Phillips, 2003)" subset: uberon_slim subset: vertebrate_core synonym: "cochlear part of bony labyrinth" EXACT [] synonym: "lagena" EXACT SENSU [XAO:0000197] synonym: "cochlear organ" RELATED [BTO:0000267] xref: AAO:0000253 ! lagena xref: BTO:0000267 xref: EFO:0000357 ! cochlea xref: FMA:60201 ! Cochlea xref: GAID:724 ! cochlea xref: VHOG:0000691 ! cochlea xref: MA:0000240 ! cochlea xref: MAT:0000144 ! cochlea xref: MIAA:0000144 ! cochlea xref: ncithesaurus:Cochlea xref: NIF_GrossAnatomy:birnlex_1190 ! Cochlea xref: NIF_GrossAnatomy:birnlex_883 xref: TAO:0000374 ! lagena xref: XAO:0000197 ! lagena xref: ZFA:0000374 ! lagena xref: OpenCyc:Mx4rvqfJmJwpEbGdrcN5Y29ycA ! cochlea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Cochlea-crosssection.png/200px-Cochlea-crosssection.png xref: EMAPA:17597 ! cochlea xref: MESH:A09.246.631.246 ! cochlea xref: EV:0100363 ! cochlea is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001839 ! bony labyrinth xref: SCTID:181187008 ! Entire cochlea xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Cochlea-crosssection.svg property_value: external_definition "A spiral-shaped cavity in the petrous portion of the temporal bone of the inner ear, containing the nerve endings essential for hearing and forming one of the divisions of the labyrinth. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000691", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/cochlea", source="http://bgee.unil.ch/"} property_value: homology_notes "Because achieving high sensitivity is generally advantageous for auditory organs, it is not surprising that evidence for cochlear amplification is also seen in nonmammals. Spontaneous otoacoustic emissions (SOAEs) are narrow-band sound signals emitted from the inner ear, and it is generally assumed that their energy derives from the hair-cell molecular motors underlying cochlear amplification. However, all terrestrial vertebrates studied so far (including amphibians) show very similar SOAEs. The most parsimonious explanation for the universality of this phenomena is that some kind of amplifying mechanism is at least as old as land vertebrates themselves.[well established][VHOG]" xsd:string {external_class="VHOG:0000691", ontology="VHOG", source="DOI:10.1016/S0959-4388(98)80033-0 Manley GA\, Koeppl C\, Phylogenetic development of the cochlea and its innervation. Current Opinion in Neurobiology (1998)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "cochlear" xsd:string xref: UMLS:C0009195 [Term] id: UBERON:0007223 name: osseus cochlea def: "The osseous cochlea is the bony foundation that forms the small shell arrangement for the cochlear nerve." [http://www.innerbody.com/image_nerv14/nerv175.html] comment: todo - check this. in MA, cochlea is not part of the bony labyrinth xref: MA:0000239 ! osseus cochlea is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001839 ! bony labyrinth relationship: part_of UBERON:0001844 ! cochlea [Term] id: UBERON:0001847 name: lobule of pinna def: "The earlobe is, in humans and many other animals, the soft lower part of the external ear. It is the lowermost portion of the human pinna, projecting below the antitragus. The earlobe is composed of tough areolar and adipose (fatty) connective tissues, lacking the firmness and elasticity of the rest of the pinna. Since the earlobe does not contain cartilage the earlobe has a large blood supply and may help to warm the ears and maintain balance but generally earlobes are not considered to have any major biological function. [WP,unvetted]." [Wikipedia:Ear_lobe] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "auricular lobule" EXACT [] synonym: "earlobe" EXACT [] synonym: "ear lobe" EXACT [] synonym: "ear lobule" RELATED [] synonym: "lobe of ear" EXACT [] synonym: "lobule of auricle" RELATED [] synonym: "lobule of auricle of ear" EXACT [] synonym: "pinna lobule" EXACT [] xref: FMA:60984 ! Lobule of pinna xref: MA:0002468 ! ear lobe is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001757 ! pinna synonym: "lobulus auriculae" EXACT LATIN [FMA:TA, FMA:60984] xref: ncithesaurus:Lobule_of_the_Auricle ! Lobule of the Auricle xref: SCTID:362544006 ! Entire ear lobule xref: UMLS:C0229315 [Term] id: UBERON:0001848 name: auricular cartilage def: "cartilage of the pinna and much of the external ear canal." [http://medical-dictionary.thefreedictionary.com/auricular+cartilage] synonym: "cartilage of pinna" EXACT [FMA:61013] xref: FMA:61013 ! Auricular cartilage xref: MA:0001227 ! auricular cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0001757 ! pinna relationship: part_of UBERON:0001757 {source="FMA"} ! pinna xref: SCTID:279627003 ! Entire auricular cartilage [Term] id: UBERON:0001750 name: lacrimal apparatus def: "The lacrimal apparatus is the physiologic system containing the orbital structures for tear production and drainage. It consists of: (a) the lacrimal gland, which secretes the tears, and its excretory ducts, which convey the fluid to the surface of the eye; (b) the lacrimal canaliculi, the lacrimal sac, and the nasolacrimal duct, by which the fluid is conveyed into the cavity of the nose. [WP,unvetted]." [Wikipedia:Lacrimal_apparatus] comment: todo - resolve canaliculus vs tear duct vs lacrimal vs nasolacrimal. AO notes: this is an eye appendage in ncit, along with eyelid and eyebrow. in MA, part of eye surface part_of eye synonym: "nasolacrimal drainage system" RELATED [UBERON:cjm] subset: uberon_slim xref: FMA:55605 ! Lacrimal apparatus xref: GAID:901 ! lacrimal apparatus xref: MA:0000274 ! lacrimal apparatus xref: ncithesaurus:Lacrimal_Apparatus ! Lacrimal Apparatus xref: MESH:A09.371.463 ! lacrimal apparatus is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0000019 {source="FMA", source="MA"} ! camera-type eye relationship: part_of UBERON:0010409 {source="MA"} ! eye surface synonym: "apparatus lacrimalis" RELATED LATIN [Wikipedia:Lacrimal_apparatus] xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Gray896.png xref: UMLS:C0022903 [Term] id: UBERON:0010284 name: lacrimal punctum def: "A minute orifice on the summit of the papillae lacrimales, which is the commencement point of the lacrimal canaliculi." [Wikipedia:Lacrimal_punctum] is_a: UBERON:0000161 {source="FMA"} ! orifice relationship: part_of UBERON:0001750 {source="cjm"} ! lacrimal apparatus xref: FMA:59365 ! lacrimal punctum xref: SCTID:263344003 ! Entire lacrimal punctum xref: http://upload.wikimedia.org/wikipedia/commons/5/53/Gray895.png [Term] id: UBERON:0001770 name: lacrimal canaliculus def: "The lacrimal canaliculi, also known as the lacrimal canals or lacrimal ducts, are the small channels in each eyelid that commence at minute orifices, termed puncta lacrimalia, on the summits of the papillae lacrimales, seen on the margins of the lids at the lateral extremity of the lacus lacrimalis. The superior duct, the smaller and shorter of the two, at first ascends, and then bends at an acute angle, and passes medialward and downward to the lacrimal sac. The inferior duct at first descends, and then runs almost horizontally to the lacrimal sac. At the angles they are dilated into ampullæ. Microscopically, they are lined by nonkeratinizing stratified squamous epithelium surrounded by fibrous tissue. Outside the latter is a layer of striped muscle, continuous with the lacrimal part of the Orbicularis oculi; at the base of each lacrimal papilla the muscular fibers are circularly arranged and form a kind of sphincter. [WP,unvetted]." [Wikipedia:Lacrimal_canaliculi] synonym: "canaliculus lacrimalis" RELATED LATIN [Wikipedia:Lacrimal_canaliculi] comment: todo - resolve canaliculus vs tear duct vs lacrimal vs nasolacrimal subset: uberon_slim xref: FMA:58245 ! Lacrimal canaliculus xref: MA:0001294 ! lacrimal canaliculus xref: ncithesaurus:Lacrimal_Canaliculus ! Lacrimal Canaliculus is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001850 ! lacrimal duct xref: SCTID:263348000 ! Entire lacrimal canaliculus xref: UMLS:C0459631 [Term] id: UBERON:0001850 name: lacrimal duct def: "Organ with organ cavity which connects the vestibule of the conjunctival sac to the nasal cavity. Examples: There are only two lacrimal ducts, the right and the left lacrimal ducts.[FMA]" [FMA:61063, Wikipedia:Lacrimal_canaliculi] comment: todo - resolve canaliculus vs tear duct vs lacrimal vs nasolacrimal subset: uberon_slim synonym: "tear duct" RELATED [MA:0001295] synonym: "lacrimal caniculus" RELATED [Wikipedia:Lacrimal_duct] xref: FMA:61063 ! Lacrimal duct xref: MA:0001295 ! lacrimal duct xref: EMAPA:19245 ! tear duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0001750 {source="FMA"} ! lacrimal apparatus relationship: only_in_taxon NCBITaxon:32523 {source="ISBN:9780674021839"} ! Tetrapoda [Term] id: UBERON:0002392 name: nasolacrimal duct def: "The nasolacrimal duct (sometimes called tear duct) carries tears from the lacrimal sac into the nasal cavity. Excess tears flow through nasolacrimal duct which opens in the nose. This is the reason the nose starts to run when a person is crying or has watery eyes from an allergy, and why one can sometimes taste eye drops. Like the lacrimal sac, the duct is lined by stratified columnar epithelium containing mucus-secreting goblet cells, and is surrounded by connective tissue. Obstruction of the nasolacrimal duct leads to the excess overflow of tears called epiphora. A congenital obstruction can cause cystic expansion of the duct and is called a dacrocystocele or Timo cyst. Persons with dry eye conditions can be fitted with punctal plugs that seal the ducts to limit the amount of fluid drainage and retain moisture. The canal containing the nasolacrimal duct is called the nasolacrimal canal. [WP,unvetted]." [Wikipedia:Nasolacrimal_duct] comment: todo - resolve canaliculus vs tear duct vs lacrimal vs nasolacrimal subset: uberon_slim synonym: "nasolacrimal duct - posterior naris" BROAD [VHOG:0000664] xref: EHDAA:7849 ! nasolacrimal duct xref: EHDAA:9094 ! nasolacrimal duct xref: FMA:9703 ! Nasolacrimal duct xref: GAID:902 ! nasolacrimal duct xref: MA:0001299 ! nasolacrimal duct xref: AAO:0000643 ! nasolarimal duct xref: OpenCyc:Mx4rv6PJy5wpEbGdrcN5Y29ycA xref: ncithesaurus:Nasolacrimal_Duct ! Nasolacrimal Duct xref: OpenCyc:Mx4rv6PJy5wpEbGdrcN5Y29ycA ! nasolacrimal duct xref: EHDAA2:0001237 ! nasolacrimal duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Gray896.png/200px-Gray896.png xref: EMAPA:17853 ! naso-lacrimal duct xref: MESH:A09.371.463.640 ! nasolacrimal duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0001850 {source="FMA"} ! lacrimal duct relationship: develops_from UBERON:0006266 ! nasolacrimal groove xref: SCTID:280643009 ! Entire nasolacrimal duct synonym: "d. nasolacrimalis" RELATED LATIN [Wikipedia:Nasolacrimal_duct] xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Gray896.png xref: VHOG:0000664 ! nasolacrimal duct - posterior naris property_value: homology_notes "The nasolacrimal duct is probably homologous to the posterior (excurrent) naris of actinopterygian fishes.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000664", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.256", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0027437 [Term] id: UBERON:0001851 name: cortex def: "Outermost layer of an organ[WP]." [Wikipedia:Cortex_(anatomy)] comment: Note that this class is used more generically than in FMA, and includes e.g. cortex of hair synonym: "cortex of organ" EXACT [] synonym: "cortex" EXACT [FMA:61109] subset: uberon_slim subset: upper_level xref: EFO:0000383 ! cortex xref: galen:Cortex xref: FMA:61109 ! Cortex xref: EHDAA:9344 ! cortex is_a: UBERON:0000064 ! organ part relationship: surrounds UBERON:0000062 ! organ property_value: has_relational_adjective "cortical" xsd:string [Term] id: UBERON:0001863 name: scala vestibuli def: "Scala vestibuli is a perilymph filled cavity inside the cochlea of the inner ear. It is separated from the scala media by Reissner's membrane and extends from the oval window to the helicotrema where it joins scala tympani. [WP,unvetted]." [Wikipedia:Scala_vestibuli] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:61269 ! Scala vestibuli xref: MA:0001206 ! scala vestibuli xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/19/Gray923.png/200px-Gray923.png is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001844 ! cochlea relationship: located_in UBERON:0002278 ! perilymphatic space xref: SCTID:362578000 ! Entire scala vestibuli xref: http://upload.wikimedia.org/wikipedia/commons/1/19/Gray923.png xref: http://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Cochlea-crosssection.png/250px-Cochlea-crosssection.png [Term] id: UBERON:0001864 name: scala tympani def: "Scala tympani is one of the perilymph-filled cavities in the cochlear labyrinth. It is separated from the scala media by the basilar membrane, and it extends from the round window to the helicotrema, where it continues as scala vestibuli. The purpose of the perilymph-filled scala tympani and scala vestibuli is to transduce the movement of air that causes the tympanic membrane and the ossicles to vibrate, to movement of liquid and the basilar membrane. This movement is conveyed to the organ of Corti inside the scala media, composed of hair cells attached to the basilar membrane and their stereocilia embedded in the tectorial membrane. The movement of the basilar membrane compared to the tectorial membrane causes the sterocilia to bend. They then depolarise and send impulses to the brain via the cochlear nerve. This produces the sensation of sound. [WP,unvetted]." [Wikipedia:Scala_tympani] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:61272 ! Scala tympani xref: GAID:879 ! scala tympani xref: MA:0001205 ! scala tympani xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray921.png/200px-Gray921.png xref: MESH:A09.246.631.246.848 ! scala tympani is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001844 ! cochlea relationship: located_in UBERON:0002278 ! perilymphatic space xref: SCTID:362579008 ! Entire scala tympani xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray921.png [Term] id: UBERON:0008813 name: helicotrema def: "The part of the cochlear labyrinth where the scala tympani and the scala vestibuli meet. It is the main component of the cochlear apex. The hair cells in this area best detect low frequency sounds." [Wikipedia:Helicotrema] synonym: "Scarpa's orifice" EXACT [FMA:61275] synonym: "cochlear apex" BROAD [Wikipedia:Cochlea] synonym: "apex of cochlea" BROAD [Wikipedia:Cochlea] is_a: UBERON:0000161 {source="FMA"} ! orifice relationship: part_of UBERON:0002499 {source="Wikipedia"} ! cochlear labyrinth xref: FMA:61275 ! helicotrema xref: SCTID:279775003 ! Entire helicotrema xref: ncithesaurus:Helicotrema ! Helicotrema xref: http://upload.wikimedia.org/wikipedia/commons/1/19/Gray923.png xref: UMLS:C0229512 [Term] id: UBERON:0008809 name: foramina of scarpa def: "In the maxilla, occasionally two additional canals are present in the middle line of the palatine process; they are termed the foramina of Scarpa, and when present transmit the nasopalatine nerves, the left passing through the anterior, and the right through the posterior canal." [Wikipedia:Foramina_of_Scarpa] synonym: "foramina of scarpa" RELATED [Wikipedia:Foramina_of_Scarpa] is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0005871 ! palatine process of maxilla relationship: surrounds UBERON:0008810 ! nasopalatine nerve xref: Wikipedia:Foramina_of_Scarpa ! foramina of scarpa xref: http://upload.wikimedia.org/wikipedia/commons/4/4a/Gray160.png [Term] id: UBERON:0008810 ! nasopalatine nerve name: nasopalatine nerve def: "One branch of the posterior superior nasal branches (trigeminal, maxillary branch), longer and larger than the others, is named the nasopalatine nerve (sometimes called the long sphenopalatine nerve). It enters the nasal cavity through the sphenopalatine foramen, passes across the roof of the nasal cavity below the orifice of the sphenoidal sinus to reach the septum, and then runs obliquely downward and forward between the periosteum and mucous membrane of the lower part of the septum. It descends to the roof of the mouth through the incisive canal and communicates with the corresponding nerve of the opposite side and with the greater palatine nerve. It supplies the palatal structures around the upper central and lateral incisors and the canines (the upper front six teeth). It also furnishes a few filaments to the mucous membrane of the nasal septum. The medial superior posterior nasal branches of maxillary nerve usually branches from the nasopalatine nerve." [Wikipedia:Nasopalatine_nerve] synonym: "naso-palatine nerve" RELATED [Wikipedia:Nasopalatine_nerve] synonym: "nasopalatine" RELATED [Wikipedia:Nasopalatine_nerve] synonym: "nasopalatine nerves" RELATED [Wikipedia:Nasopalatine_nerve] synonym: "Scarpa's nerve" EXACT [FMA:52797] is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0000377 {source="FMA"} ! maxillary nerve xref: FMA:52797 ! nasopalatine nerve synonym: "nervus nasopalatinus" RELATED LATIN [Wikipedia:Nasopalatine_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray858.png [Term] id: UBERON:0001865 name: cartilaginous external acoustic tube comment: This class was created automatically from a combination of ontologies synonym: "cartilaginous external acoustic meatus" EXACT [] synonym: "cartilaginous part of external acoustic meatus" EXACT [] synonym: "external acoustic meatus cartilaginous part" EXACT [] xref: FMA:61289 ! Cartilaginous external acoustic tube xref: MA:0001234 ! external acoustic meatus cartilaginous part is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001352 ! external acoustic meatus synonym: "meatus acusticus externus cartilagineus" EXACT LATIN [FMA:TA, FMA:61289] [Term] id: UBERON:0001866 name: sebum def: "Fatty lubricant matter secreted by sebaceous glands, and made of made of triglyceride oils, wax, squalene, and metabolytes of fat-producing cells[BTO,WP]." [BTO:0001981, Wikipedia:Sebaceous_glands#Sebum] comment: The composition of sebum varies across species. In humans, the lipid content is as follows: 25% wax monoesters, 41% triglycerides, 16% free fatty acids, 12% squalene; Sapienic acid is a sebum fatty acid that is unique to humans. subset: uberon_slim xref: ENVO:02000037 xref: FMA:61304 ! Sebum xref: GAID:1168 ! sebum xref: MA:0002538 ! sebum xref: ncithesaurus:Sebum ! Sebum xref: BTO:0001981 ! sebum xref: MESH:A12.200.702 ! sebum intersection_of: UBERON:0000456 ! bodily secretion intersection_of: secreted_by UBERON:0001821 ! sebaceous gland relationship: has_part CHEBI:15440 ! squalene xref: UMLS:C0036511 [Term] id: UBERON:0001867 name: cartilage of external ear def: "A cartilage that is part of a external ear [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "external ear cartilage" EXACT [] synonym: "auricular region cartilage" EXACT [OBOL:automatic] synonym: "auricular region of head cartilage" EXACT [OBOL:automatic] synonym: "cartilage of auricular region" EXACT [OBOL:automatic] synonym: "cartilage of auricular region of head" EXACT [OBOL:automatic] synonym: "cartilage of outer ear" EXACT [OBOL:automatic] synonym: "outer ear cartilage" EXACT [OBOL:automatic] xref: FMA:61339 ! Cartilage of external ear xref: MA:0001886 ! external ear cartilage xref: GAID:103 ! ear cartilage xref: ncithesaurus:External_Ear_Cartilage ! External Ear Cartilage xref: MESH:A02.165.207 ! ear cartilage is_a: UBERON:0001996 ! elastic cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0001691 ! external ear relationship: part_of UBERON:0001691 ! external ear xref: UMLS:C0013445 [Term] id: UBERON:0001868 name: skin of chest def: "A zone of skin that is part of a chest [Automatically generated definition]." [OBOL:automatic] comment: check FMA:61415 synonym: "chest skin" EXACT [] synonym: "anterior thoracic region zone of skin" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax zone of skin" EXACT [OBOL:automatic] synonym: "chest zone of skin" EXACT [OBOL:automatic] synonym: "front of thorax zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of anterior thoracic region" EXACT [OBOL:automatic] synonym: "zone of skin of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "zone of skin of chest" EXACT [OBOL:automatic] synonym: "zone of skin of front of thorax" EXACT [OBOL:automatic] synonym: "zone of skin of anterior chest" EXACT [FMA:61416] synonym: "zone of skin of anterior part of thorax" EXACT [FMA:61416] xref: MA:0000553 ! chest skin xref: FMA:61416 ! Zone of skin of anterior chest xref: FMA:61417 ! Zone of skin of pectoral part of chest is_a: UBERON:0001418 ! skin of thorax intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001443 ! chest relationship: part_of UBERON:0001443 ! chest xref: SCTID:181496004 ! Entire skin of chest synonym: "zone of skin of pectoral part of chest" RELATED [FMA:61417] [Term] id: UBERON:0001869 ! cerebral hemisphere name: cerebral hemisphere def: "One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA]" [Wikipedia:Cerebral_hemisphere, FMA:FMA] subset: uberon_slim synonym: "hemispherium cerebri" RELATED LATIN [Wikipedia:Cerebral_hemisphere] synonym: "telencephalic vesicle" RELATED [] xref: BTO:0000231 xref: FMA:61817 ! Cerebral hemisphere xref: galen:CerebralHemisphere xref: MA:0000133 ! cerebral hemisphere xref: ncithesaurus:Cerebral_Hemisphere xref: EFO:0002521 ! cerebral hemisphere xref: VHOG:0001639 ! cerebral hemisphere xref: OpenCyc:Mx4rvigx5ZwpEbGdrcN5Y29ycA ! cerebral hemisphere xref: NIF_GrossAnatomy:birnlex_1042 ! Cerebrum is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001893 ! telencephalon relationship: in_lateral_side_of UBERON:0000955 ! brain xref: AAO:0010480 ! cerebral hemisphere xref: SCTID:278251007 ! Entire cerebral hemisphere xref: http://upload.wikimedia.org/wikipedia/commons/9/92/Hemispheres.png property_value: external_definition "Part of the telencephalon consisting of either of the two smooth, elongated halves of the cerebrum.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010480", date_retrieved="2012-06-20", source="AAO:BJB"} synonym: "hemisphere" RELATED [VHOG:0001639] property_value: homology_notes "The presence of paired evaginated hemispheres and olfactory bulbs in both agnathan and gnathostome radiations suggests that such hemispheres were also present in the common ancestor.[well established][VHOG]" xsd:string {external_class="VHOG:0001639", ontology="VHOG", source="DOI:10.1146/annurev.ne.04.030181.001505 Northcutt RG\, Evolution of the telencephalon in nonmammals. Ann. Rev. Neurosci. (1981)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0001893 {source="FMA-abduced-lr"} ! telencephalon xref: UMLS:C0228174 [Term] id: UBERON:0002812 name: left cerebral hemisphere synonym: "left hemisphere" EXACT [NIF_GrossAnatomy:birnlex_1795] xref: FMA:61819 ! Left cerebral hemisphere xref: NIF_GrossAnatomy:birnlex_1795 ! Left cerebral hemisphere xref: ncithesaurus:Left_Cerebral_Hemisphere ! Left Cerebral Hemisphere intersection_of: UBERON:0001869 ! cerebral hemisphere intersection_of: in_left_side_of UBERON:0000955 ! brain xref: SCTID:362323007 ! Entire left cerebral hemisphere def: "A cerebral hemisphere that is in the left side of a brain." [OBOL:automatic] xref: UMLS:C0228176 [Term] id: UBERON:0002813 name: right cerebral hemisphere synonym: "right hemisphere" EXACT [NIF_GrossAnatomy:birnlex_1797] xref: FMA:67292 ! Right cerebral hemisphere xref: NIF_GrossAnatomy:birnlex_1797 ! Right cerebral hemisphere xref: ncithesaurus:Right_Cerebral_Hemisphere ! Right Cerebral Hemisphere xref: OpenCyc:Mx8Ngh4rvgHsHZwpEbGdrcN5Y29ycB4rvigx5ZwpEbGdrcN5Y29ycA ! right cerebral hemisphere intersection_of: UBERON:0001869 ! cerebral hemisphere intersection_of: in_right_side_of UBERON:0000955 ! brain xref: SCTID:362322002 ! Entire right cerebral hemisphere def: "A cerebral hemisphere that is in the right side of a brain." [OBOL:automatic] xref: UMLS:C0228175 [Term] id: UBERON:0001870 name: frontal cortex def: "Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border." [Wikipedia:Frontal_lobe] comment: Editor note: Many species don't have lobes but they do have frontal cortex. Lobe isn't a really well defined term though [MM] subset: uberon_slim synonym: "frontal lobe" EXACT [FMA:61824] synonym: "frontal region" EXACT [] xref: BTO:0000484 xref: EFO:0000913 ! frontal lobe xref: FMA:61824 ! Frontal lobe xref: GAID:674 ! frontal lobe xref: MA:0000905 ! frontal cortex xref: MAT:0000505 ! frontal lobe xref: ncithesaurus:Frontal_Lobe xref: NIF_GrossAnatomy:nlx_anat_20090601 ! Frontal cortex xref: NIF_GrossAnatomy:birnlex_928 ! Frontal lobe xref: OpenCyc:Mx4rv3OJ8JwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rv3OJ8JwpEbGdrcN5Y29ycA ! frontal lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b4/Gray729.png/200px-Gray729.png xref: MESH:A08.186.211.730.885.213.270 ! frontal lobe xref: EV:0100167 ! frontal lobe xref: BM:Tel-Cx-FR ! frontal region is_a: UBERON:0000064 ! organ part relationship: adjacent_to UBERON:0001871 ! temporal lobe relationship: adjacent_to UBERON:0001872 ! parietal lobe relationship: part_of UBERON:0001950 ! neocortex synonym: "regio frontalis" EXACT LATIN [FMA:TA, FMA:61824] xref: SCTID:180920004 ! Entire frontal lobe synonym: "lobus frontalis" RELATED LATIN [Wikipedia:Frontal_lobe] xref: http://upload.wikimedia.org/wikipedia/commons/b/b4/Gray729.png xref: UMLS:C0016733 [Term] id: UBERON:0001871 name: temporal lobe def: "Temporal lobe is the ventrolateral lobe of five lobes comprising each cerebral hemisphere. It is bounded dorsally by the lateral fissure and posteriorly by an arbitrary border shared with the occipital lobe." [Wikipedia:Temporal_lobe] subset: uberon_slim synonym: "temporal cortex" EXACT [] synonym: "temporal neocortex" EXACT [DHB:TCx] xref: BTO:0001355 xref: EFO:0000917 ! temporal lobe xref: FMA:61825 ! Temporal lobe xref: GAID:635 ! temporal lobe xref: MA:0000941 ! temporal cortex xref: MAT:0000508 ! temporal lobe xref: ncithesaurus:Temporal_Lobe xref: NIF_GrossAnatomy:birnlex_1160 ! Temporal lobe xref: OpenCyc:Mx4rwQLi-ZwpEbGdrcN5Y29ycA ! temporal lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/91/Gray730.png/200px-Gray730.png xref: EMAPA:18797 ! temporal lobe xref: MESH:A08.186.211.730.885.213.863 ! temporal lobe xref: EV:0100169 ! temporal lobe xref: BM:Tel-Cx-Te ! temporal cortex is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001950 ! neocortex xref: SCTID:180921000 ! Entire temporal lobe synonym: "lobus temporalis" RELATED LATIN [Wikipedia:Temporal_lobe] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Gray730.png xref: UMLS:C0039485 [Term] id: UBERON:0001872 name: parietal lobe def: "Parietal lobe is the one of five lobes of the cerebral hemisphere which occupies the dorsal-posterior portion of the hemisphere. It is bounded by the central sulcus on its anterior border and and by the longitudinal cerebral fissure on its medial border. Posteriorly it shares an arbitrary border with the occipital lobe." [Wikipedia:Parietal_lobe] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "parietal cortex" EXACT [] synonym: "parietal region" EXACT [] synonym: "parietal neocortex" EXACT [DHB:PCx] xref: BTO:0001001 xref: EFO:0000914 ! parietal lobe xref: FMA:61826 ! Parietal lobe xref: GAID:680 ! parietal lobe xref: MA:0000916 ! parietal cortex xref: MAT:0000506 ! parietal lobe xref: ncithesaurus:Parietal_Lobe_of_the_Brain xref: NIF_GrossAnatomy:birnlex_1148 ! Parietal lobe xref: OpenCyc:Mx4rvg-typwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvg-typwpEbGdrcN5Y29ycA ! parietal lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b2/Gray726_parietal_lobe.png/200px-Gray726_parietal_lobe.png xref: MESH:A08.186.211.730.885.213.670 ! parietal lobe xref: EV:0100168 ! parietal lobe is_a: UBERON:0000064 ! organ part relationship: adjacent_to UBERON:0001871 ! temporal lobe relationship: part_of UBERON:0001950 ! neocortex synonym: "regio parietalis" EXACT LATIN [FMA:TA, FMA:61826] xref: SCTID:180922007 ! Entire parietal lobe synonym: "lobus parietalis" RELATED LATIN [Wikipedia:Parietal_lobe] xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Gray726_parietal_lobe.png xref: UMLS:C0030560 [Term] id: UBERON:0006514 ! pallidum name: pallidum def: "Part of what are called the basal ganglia of the brain which consist of the globus pallidus and the ventral pallidum." [http://www.medterms.com/script/main/art.asp?articlekey=11614] synonym: "neuraxis pallidum" EXACT [FMA:83684] synonym: "pallidum of neuraxis" EXACT [FMA:83684] xref: FMA:83684 ! pallidum of neuraxis xref: MA:0000889 ! pallidum xref: ABA:PAL ! Pallidum is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002420 {source="MA"} ! basal ganglion relationship: spatially_disjoint_from UBERON:0002435 {source="ABA"} ! striatum [Term] id: UBERON:0002778 name: ventral pallidum def: "Part of the globus pallidus, consistingo of the more medial of the two segments. In some species, e.g., primates, it is separated from the lateral segment by the fibers of the medial medullary lamina (MM)." [NIF_GrossAnatomy:birnlex_1674] synonym: "ventral pallidum" EXACT [NIF_GrossAnatomy:birnlex_1674] synonym: "ventral globus pallidus" RELATED [BTO:0004375] xref: FMA:77613 ! Ventral pallidum xref: NIF_GrossAnatomy:birnlex_1674 ! Ventral pallidum xref: BTO:0004375 ! ventral globus pallidus xref: BM:Tel-VPa ! ventral pallidum xref: ABA:PALv ! Pallidum, ventral region is_a: UBERON:0006514 {source="FMA"} ! pallidum relationship: part_of UBERON:0001875 {source="BTO", source="NIF-def"} ! globus pallidus [Term] id: UBERON:0006516 name: dorsal pallidum synonym: "dorsal globus pallidus" RELATED [BTO:0004376] xref: FMA:77619 ! dorsal pallidum xref: BTO:0004376 ! dorsal globus pallidus xref: ABA:PALd ! Pallidum, dorsal region is_a: UBERON:0006514 {source="FMA"} ! pallidum relationship: part_of UBERON:0001875 {source="BTO"} ! globus pallidus [Term] id: UBERON:0001875 name: globus pallidus def: "Subcortical nucleus, functionally part of the basal ganglia, which consists of two segments the external (or lateral) and internal (or medial) separated by the medial medullary lamina in primates. In rodents, The globus pallidus lateral is separated from the medial segment by the fibers of the internal capsule/cerebral peduncle[NIF]. Nucleus of brain which is located medially to the putamen and laterally to the internal capsule[FMA]." [NIF_GrossAnatomy:birnlex_1234, Wikipedia:Globus_pallidus, FMA:61835] comment: BTO and MA are inconsistent w.r.t striatum and pallidum being non-overlapping as in ABA. Note that we have pallidum as part_of basal gangion, so we can make the direct link to basal ganglion. ISBN10:1588900649 says: ... a derivative of the diencephalon, seperates as a result of growing fibers of theinternal capsule and is finally displaced into telencephalon. only a small medial remnannt remains, the entopeduncular nucleus. The globus pallidus should be regarded as part of the subthalamus subset: uberon_slim synonym: "paleostriatum" EXACT [Wikipedia:Globus_pallidus] synonym: "pale body" EXACT [NIF_GrossAnatomy:birnlex_1234] synonym: "pallidum" RELATED [NIF_GrossAnatomy:birnlex_1234, Wikipedia:Globus_pallidus, GO:0021759] synonym: "pallidium" RELATED [Wikipedia:Globus_pallidus] xref: EFO:0000905 ! globus pallidus xref: FMA:61835 ! Globus pallidus xref: GAID:668 ! globus pallidus xref: MA:0000890 ! globus pallidus xref: MAT:0000510 ! globus pallidus xref: NIF_GrossAnatomy:birnlex_1234 ! Globus pallidus xref: ncithesaurus:Globus_Pallidus ! Globus Pallidus xref: BTO:0002246 ! globus pallidus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Brain_structure.gif/200px-Brain_structure.gif xref: MESH:A08.186.211.730.885.105.487.397 ! globus pallidus xref: EV:0100188 ! globus pallidus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0002420 {source="NIF_GrossAnatomy"} ! basal ganglion relationship: overlaps UBERON:0002263 {source="BTO-weakened"} ! lentiform nucleus relationship: part_of UBERON:0006514 {source="MA"} ! pallidum relationship: develops_from_part_of UBERON:0001894 {source="ISBN10:1588900649", source="GO"} ! diencephalon xref: SCTID:362361005 ! Entire globus pallidus xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Brain_structure.gif xref: UMLS:C0017651 property_value: has_relational_adjective "pallidal" xsd:string [Term] id: UBERON:0001876 name: amygdala def: "Subdivision of basal ganglion of telencephalon which is an almond-shaped gray mass in the dorsomedial part of the temporal lobe[FMA]" [Wikipedia:Amygdala, FMA:61841] comment: AO notes: MA and FMA differ on relationship to basal ganglion. The FMA text def suggests a subdivision, but it is classified as a subtype subset: uberon_slim synonym: "amygdaloid area" RELATED [] synonym: "amygdaloid body" EXACT [] synonym: "amygdaloid complex" EXACT [NIF_GrossAnatomy:birnlex_1241] synonym: "amygdaloid nuclear complex" EXACT [] synonym: "amygdaloid nuclear groups" EXACT [] synonym: "archistriatum" EXACT [] synonym: "amygdaloid nuclear group" RELATED [BTO:0001042] synonym: "corpus amygdaloideum" RELATED [BTO:0001042] synonym: "nucleus amygdalae" RELATED [BTO:0001042] xref: BTO:0001042 xref: EFO:0000252 ! amygdala xref: FMA:61841 ! Amygdala xref: GAID:616 ! amygdala xref: VHOG:0001277 ! amygdala xref: MA:0000887 ! amygdala xref: MAT:0000289 ! amygdala xref: MIAA:0000289 ! amygdala xref: NIF_GrossAnatomy:birnlex_1241 ! Amygdala xref: ncithesaurus:Amygdala ! Amygdala xref: OpenCyc:Mx4rwJC_2ZwpEbGdrcN5Y29ycA ! amygdala xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Amyg.png/200px-Amyg.png xref: MESH:A08.186.211.577.090 ! amygdala xref: EV:0100189 ! amygdala xref: EV:0100190 ! amygdaloid nucleus xref: BM:Tel-Am ! amygdala xref: SCTID:279404004 ! Entire amygdaloid nucleus is_a: UBERON:0002420 {source="FMA"} ! basal ganglion relationship: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0001871 {source="BTO"} ! temporal lobe relationship: part_of UBERON:0000349 {source="FMA"} ! limbic system relationship: part_of UBERON:0001871 {source="BTO"} ! temporal lobe synonym: "corpus amygdaloideum" RELATED LATIN [Wikipedia:Amygdala] xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Amyg.png synonym: "amygdaloid nucleus" RELATED [FMA:61841] property_value: homology_notes "One part of the striatum is called the archistriatum. (...) The archistriatum of fishes consists of several indistinctly segregated nuclei called the amygdaloid (...) complex. Tetrapods retain the structure, and in mammals the corresponding amygdala is a globular mass that tends to be ventral to the other basal nuclei.[well established][VHOG]" xsd:string {external_class="VHOG:0001277", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.342", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "amygdalar" xsd:string xref: UMLS:C0002708 [Term] id: UBERON:0001877 name: medial septal nucleus comment: This class was created automatically from a combination of ontologies synonym: "medial parolfactory nucleus" EXACT [] synonym: "medial septum" NARROW [NIF_GrossAnatomy:birnlex_1668] xref: FMA:61879 ! Medial septal nucleus (also: UBERON:0007629 'medial septal complex') (also: UBERON:0007629 'medial septal complex') xref: MA:0000935 ! medial septal nucleus xref: NIF_GrossAnatomy:birnlex_1668 ! Medial septal nucleus xref: BTO:0002446 ! medial septum xref: ABA:MS ! Medial septal nucleus xref: BM:Tel-Spt-SMN ! medial septal nucleus is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0001878 name: septofimbrial nucleus comment: This class was created automatically from a combination of ontologies synonym: "scattered nucleus of the septum" EXACT [] synonym: "nucleus septofibrialis" EXACT [NIF_GrossAnatomy:birnlex_730] xref: FMA:61881 ! Septofimbrial nucleus xref: MA:0000938 ! septofimbrial nucleus xref: NIF_GrossAnatomy:birnlex_730 ! Septofimbrial nucleus xref: ABA:SF ! Septofimbrial nucleus xref: BM:SFN ! septofimbrial nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002667 {source="ABA"} ! lateral septal nucleus relationship: spatially_disjoint_from UBERON:0007630 {source="ABA"} ! septohippocampal nucleus [Term] id: UBERON:0001879 name: nucleus of diagonal band comment: This class was created automatically from a combination of ontologies synonym: "diagonal band nucleus" EXACT [] synonym: "nucleus of the diagonal band of broca" EXACT [] synonym: "olfactory area (roberts)" EXACT [] xref: FMA:61882 ! Nucleus of diagonal band xref: MA:0000936 ! nucleus of diagonal band xref: NIF_GrossAnatomy:birnlex_719 ! Nucleus of diagonal band xref: ABA:NDB ! Diagonal band nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002663 {source="FMA"} ! septal nuclear complex relationship: part_of UBERON:0007629 {source="MA"} ! medial septal complex xref: ncithesaurus:Nucleus_of_Diagonal_Band ! nucleus of diagonal band xref: EHDAA2:0004708 ! nucleus of the diagonal band xref: UMLS:C0175227 [Term] id: UBERON:0001880 name: bed nucleus of stria terminalis def: "A brain structure in the forebrain wrapped around the stria terminalis. It's largest extent can be found around the crossing of the anterior commissure[INCF]." [INCF:Seattle_mtg_2010, Wikipedia:Stria_terminalis#Bed_nucleus_of_the_stria_terminalis] synonym: "nucleus of stria terminalis" EXACT [FMA:61884] synonym: "intercalate nucleus of stria terminalis" EXACT [] synonym: "nuclei of stria terminalis" EXACT [] synonym: "stria terminalis nucleus" EXACT [] synonym: "BST" BROAD [INCF:Seattle_mtg_2010] synonym: "bed nucleus of the stria terminalis" EXACT [NIF_GrossAnatomy:birnlex_724] synonym: "bed nucleus stria terminalis (johnson)" EXACT [NIF_GrossAnatomy:birnlex_724] synonym: "interstitial nucleus of stria terminalis" EXACT [NIF_GrossAnatomy:birnlex_724] xref: FMA:61884 ! Nucleus of stria terminalis xref: MA:0000925 ! bed nucleus of stria terminalis xref: NIF_GrossAnatomy:birnlex_724 ! Nucleus of stria terminalis xref: BTO:0002698 ! bed nucleus of stria terminalis xref: EFO:0001971 ! nucleus of terminal stria xref: BM:BNST ! bed nucleus of stria terminalis xref: ABA:BST ! Bed nuclei of the stria terminalis is_a: UBERON:0002308 ! nucleus of brain relationship: surrounds UBERON:0003029 ! stria terminalis relationship: part_of UBERON:0002663 {source="FMA"} ! septal nuclear complex synonym: "nucleus striae terminalis" EXACT LATIN [FMA:TA, FMA:61884] [Term] id: UBERON:0011173 name: anterior division of bed nuclei of stria terminalis def: "The term anterior nuclei of stria terminalis refers to one of two divisions of the nuclei of stria terminalis based on topology, connectivity and multiple stains in the rat ( Swanson-2004 ) and the mouse ( Dong-2004 ). The other division consists of the posterior nuclei of stria terminalis. The anterior division includes the anterolateral area of stria terminalis, anteromedial area of stria terminalis, oval nucleus of stria terminalis, juxtacapsular nucleus of stria terminalis, rhomboid nucleus of stria terminalis, dorsomedial nucleus of stria terminalis, fusiform nucleus of stria terminalis, ventral nucleus of stria terminalis, and the magnocellular nucleus of stria terminalis" [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=2753] synonym: "anterior nuclei of stria terminalis" EXACT [http://braininfo.rprc.washington.edu] synonym: "anterior division" BROAD [MA:0000926] synonym: "bed nuclei of the stria terminalis, anterior division" EXACT [ABA:BSTa] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001880 {source="MA"} ! bed nucleus of stria terminalis xref: MA:0000926 ! anterior division xref: ABA:BSTa ! Bed nuclei of the stria terminalis, anterior division [Term] id: UBERON:0007627 name: magnocellular nucleus of stria terminalis def: "." [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=3220] comment: the magnocellular nucleus projects to virtually all known major parts of the brain network that controls pelvic functions, including micturition, defecation, and penile erection, as well as to brain networks controlling nutrient and body water homeostasis. This and other evidence suggests that the magnocellular nucleus is part of a corticostriatopallidal differentiation modulating and coordinating pelvic functions with the maintenance of nutrient and body water homeostasis[PMID:16304682] xref: MA:0000928 ! magnocellular nucleus xref: ABA:BSTmg ! Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus is_a: UBERON:0000125 ! neural nucleus relationship: part_of UBERON:0011173 {source="MA"} ! anterior division of bed nucleus of stria terminalis relationship: spatially_disjoint_from UBERON:0003017 {source="ABA"} ! substantia innominata relationship: has_function_in GO:0043084 {source="PMID:16304682"} ! penile erection relationship: has_function_in GO:0030421 {source="PMID:16304682"} ! defecation relationship: has_function_in GO:0060073 {source="PMID:16304682"} ! micturition synonym: "magnocellular nucleus" EXACT [MA:0000928] [Term] id: UBERON:0011175 name: fusiform nucleus of stria terminalis def: "." [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=3218] synonym: "fusiform nucleus" BROAD [MA:0000927] synonym: "bed nuclei of the stria terminalis, anterior division, fusiform nucleus" EXACT [ABA:BSTfu] is_a: UBERON:0000125 ! neural nucleus relationship: part_of UBERON:0011173 {source="MA"} ! anterior division of bed nuclei of stria terminalis xref: MA:0000927 ! fusiform nucleus xref: ABA:BSTfu ! bed nuclei of the stria terminalis, anterior division, fusiform nucleus [Term] id: UBERON:0011176 name: oval nucleus of stria terminalis def: "." [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=3214] synonym: "oval nucleus" EXACT [MA:0000929] synonym: "bed nuclei of the stria terminalis, anterior division, oval nucleus" EXACT [ABA:BSTov] is_a: UBERON:0000125 ! neural nucleus relationship: part_of UBERON:0011173 {source="MA"} ! anterior division of bed nuclei of stria terminalis xref: MA:0000929 ! oval nucleus xref: ABA:BSTov ! bed nuclei of the stria terminalis, anterior division, oval nucleus [Term] id: UBERON:0011177 name: posterior division of bed nuclei of stria terminalis def: "The term posterior nuclei of stria terminalis refers to one of two divisions of the nuclei of stria terminalis based on topology, connectivity and multiple stains in the rat ( Swanson-2004 ) and the mouse ( Dong-2004 ). The other division consists of the anterior nuclei of stria terminalis. The posterior division includes the principal nucleus of stria terminalis, interfascicular nucleus of stria terminalis, transverse nucleus of stria terminalis, premedullary nucleus of stria terminalis, dorsal nucleus of stria terminalis, the strial extension of stria terminalis, and the cell sparse zone of stria terminalis." [http://braininfo.rprc.washington.edu/CentralDirectory.aspx?ID=2754] synonym: "posterior nuclei of stria terminalis" EXACT [http://braininfo.rprc.washington.edu] synonym: "posterior division" BROAD [MA:0000930] synonym: "bed nuclei of the stria terminalis, posterior division" EXACT [ABA:BSTp] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001880 {source="MA"} ! bed nucleus of stria terminalis xref: MA:0000930 ! posterior division xref: ABA:BSTp ! Bed nuclei of the stria terminalis, posterior division [Term] id: UBERON:0011178 name: principal nucleus of stria terminalis def: "." [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=3221] is_a: UBERON:0000125 ! neural nucleus relationship: part_of UBERON:0011177 {source="MA"} ! posterior division of bed nuclei of stria terminalis synonym: "principal nucleus" BROAD [MA:0000931] synonym: "bed nuclei of the stria terminalis, posterior division, principal nucleus" EXACT [ABA:BSTpr] xref: MA:0000931 ! principal nucleus xref: ABA:BSTpr ! bed nuclei of the stria terminalis, posterior division, principal nucleus [Term] id: UBERON:0011179 name: transverse nucleus of stria terminalis def: "." [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=3223] is_a: UBERON:0000125 ! neural nucleus relationship: part_of UBERON:0011177 {source="MA"} ! posterior division of bed nuclei of stria terminalis synonym: "transverse nucleus" BROAD [MA:0000932] synonym: "bed nuclei of the stria terminalis, posterior division, transverse nucleus" EXACT [ABA:BSTtr] xref: MA:0000932 ! transverse nucleus xref: ABA:BSTtr ! bed nuclei of the stria terminalis, posterior division, transverse nucleus [Term] id: UBERON:0001881 name: island of calleja def: "The islands of Calleja (IC, ISC, or IClj) are a group of neural granule cells located within the ventral striatum in the brains of most animals. This region of the brain is part of the limbic system, where it aids in the reinforcing effects of reward-like activities. Within most species, the islands are specifically located within the olfactory tubercle; however, in primates these islands are located within the nucleus accumbens, the reward center of the brain, since the olfactory tubercle has practically disappeared in the brains of primates. Both of these structures have been implicated in the processing of incentives as well as addictions to drugs. Projections to and from the islands supplement this knowledge with their involvement in the reward pathways for both cocaine and amphetamines. [WP,unvetted]." [Wikipedia:Islands_of_Calleja] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "calleja island" EXACT [] synonym: "islands of calleja" EXACT [] xref: FMA:61888 ! Island of Calleja xref: GAID:632 ! islands of calleja xref: MA:0000977 ! islands of Calleja xref: NIF_GrossAnatomy:birnlex_1113 ! Islands of Calleja xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Islands_of_Calleja_Rat.jpg/200px-Islands_of_Calleja_Rat.jpg xref: MESH:A08.186.211.577.699.400 ! islands of calleja xref: ABA:isl ! Islands of Calleja xref: BM:Tel-ISC ! islands of Calleja is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001883 ! anterior perforated substance synonym: "insulae olfactoriae, insula callejae" RELATED LATIN [Wikipedia:Islands_of_Calleja] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Islands_of_Calleja_Rat.jpg [Term] id: UBERON:0001882 name: nucleus accumbens def: "a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia[GO]." [GO:0021768, Wikipedia:Nucleus_accumbens] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "accumbens nucleus" EXACT [] synonym: "colliculus of caudate nucleus" EXACT [] synonym: "nucleus accumbens septi" EXACT [] xref: EFO:0000906 ! accumbens nucleus xref: FMA:61889 ! Nucleus accumbens xref: GAID:672 ! nucleus accumben xref: MA:0000892 ! accumbens nucleus xref: MAT:0000512 ! accumbens nucleus xref: NIF_GrossAnatomy:birnlex_727 ! Nucleus accumbens xref: ncithesaurus:Accumbens_Nucleus ! Accumbens Nucleus xref: BTO:0001862 ! nucleus accumbens xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/93/Circuit_du_syst%C3%A8me_de_recompense.jpg/200px-Circuit_du_syst%C3%A8me_de_recompense.jpg xref: MESH:A08.186.211.730.885.105.683 ! nucleus accumben xref: ABA:ACB ! Nucleus accumbens xref: BM:Ac ! nucleus accumbens xref: EHDAA2:0004707 ! nucleus accumbens is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0000349 {source="FMA", source="GO"} ! limbic system relationship: part_of UBERON:0005403 {source="MA"} ! ventral striatum relationship: spatially_disjoint_from UBERON:0001883 {source="ABA"} ! anterior perforated substance xref: SCTID:427667007 ! Nucleus accumbens synonym: "nucleus accumbens septi" RELATED LATIN [Wikipedia:Nucleus_accumbens] xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Circuit_du_syst%C3%A8me_de_recompense.jpg xref: UMLS:C0028633 [Term] id: UBERON:0012170 name: core of nucleus accumbens synonym: "nucleus accumbens core" EXACT [NIF_GrossAnatomy:nlx_anat_20090306] synonym: "core of nucleus accumbens" EXACT [NIF_GrossAnatomy:nlx_anat_20090306] synonym: "core region of nucleus accumbens" EXACT [FMA:77383] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001882 {source="NIF_GrossAnatomy"} ! nucleus accumbens xref: NIF_GrossAnatomy:nlx_anat_20090306 ! Core of nucleus accumbens xref: EFO:0002458 ! nucleus accumbens core xref: FMA:77383 ! core region of nucleus accumbens [Term] id: UBERON:0012171 name: shell of nucleus accumbens def: "Crescent shaped outer zone of the nucleus accumbens, defined by a combination of chemoarchitecture and afferent and efferent connections. The shell is distinguished from the more centrally located core through the notable reduction in staining for the calcium-binding protein calbindin D28K, which is dense in the core and virtually absent in the shell." [NIF_GrossAnatomy:nlx_anat_20090307] synonym: "nucleus accumbens shell" EXACT [NIF_GrossAnatomy:nlx_anat_20090307] synonym: "shell of nucleus accumbens" EXACT [NIF_GrossAnatomy:nlx_anat_20090307] synonym: "shell region of nucleus accumbens" EXACT [FMA:77387] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001882 {source="NIF_GrossAnatomy"} ! nucleus accumbens xref: FMA:77387 ! shell region of nucleus accumbens xref: NIF_GrossAnatomy:nlx_anat_20090307 ! Shell of nucleus accumbens xref: EFO:0002459 ! nucleus accumbens shell [Term] id: UBERON:0001884 name: phrenic nerve def: "The phrenic nerve arises from the third, fourth, and fifth cervical spinal nerves (C3-C5) in humans. [WP,unvetted]." [Wikipedia:Phrenic_nerve] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "diaphragmatic nerve" RELATED [BTO:0001063] synonym: "nervus phrenicus" RELATED [BTO:0001063] synonym: "phrenic" RELATED [BTO:0001063] xref: BTO:0001063 xref: FMA:6191 ! Phrenic nerve xref: GAID:848 ! phrenic nerve xref: VHOG:0000728 ! phrenic nerve xref: MA:0001170 ! phrenic nerve xref: ncithesaurus:Phrenic_Nerve ! Phrenic Nerve xref: OpenCyc:Mx4rvtmdUJwpEbGdrcN5Y29ycA ! phrenic nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3c/Gray806.png/200px-Gray806.png xref: EMAPA:17813 ! phrenic xref: MESH:A08.800.800.720.150.700 ! phrenic nerve xref: EHDAA:4677 ! phrenic is_a: UBERON:0002003 ! peripheral nerve relationship: located_in UBERON:0002224 ! thoracic cavity xref: SCTID:280344009 ! Entire phrenic nerve synonym: "nervus phrenicus" RELATED LATIN [Wikipedia:Phrenic_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/3/3c/Gray806.png property_value: external_definition "A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000728", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/phrenic+nerve", source="http://bgee.unil.ch/"} xref: UMLS:C0031774 [Term] id: UBERON:0001885 name: dentate gyrus of hippocampal formation def: "The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus[GO]." [Wikipedia:Dentate_gyrus] comment: BTO says dentate gyrus = fascia dentata + hilus. Note that GO classifies dentate gyrus development under hippocampus development subset: uberon_slim synonym: "area dentata" EXACT [] synonym: "dentate gyrus" EXACT [] synonym: "fascia dentata" NARROW [] synonym: "gyrus dentatus" RELATED [BTO:0002496] synonym: "hippocampal dentate gyrus" RELATED [BTO:0002496] xref: FMA:61922 ! Dentate gyrus of hippocampal formation xref: GAID:624 ! dentate gyrus xref: MA:0000190 ! dentate gyrus xref: NIF_GrossAnatomy:birnlex_1178 ! Dentate gyrus xref: ncithesaurus:Dentate_Gyrus ! Dentate Gyrus xref: BTO:0002496 ! dentate gyrus xref: BTO:0002615 ! fascia dentata xref: EFO:0001366 ! dentate gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ab/HippocampalRegions.jpg/200px-HippocampalRegions.jpg xref: EMAPA:19037 ! dentate gyrus xref: MESH:A08.186.211.577.405.200 ! dentate gyrus xref: ABA:DG ! Dentate gyrus xref: BM:Tel-DG ! dentate gyrus is_a: UBERON:0000200 {source="FMA"} ! gyrus relationship: part_of UBERON:0002421 {source="MA"} ! hippocampal formation relationship: spatially_disjoint_from UBERON:0001954 ! Ammon's horn relationship: spatially_disjoint_from UBERON:0001954 {source="ABA"} ! Ammon's horn relationship: spatially_disjoint_from UBERON:0002601 {source="ABA"} ! fasciolar gyrus xref: SCTID:279211002 ! Entire dentate gyrus synonym: "gyrus dentatus" RELATED LATIN [Wikipedia:Dentate_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/HippocampalRegions.jpg xref: UMLS:C0152314 [Term] id: UBERON:0001887 name: internal capsule def: "Internal capsule is an organ subdivision of the telencephalon which is made up primarily of myelinated axonal neural tissue (white matter). The internal capsule is a major set of fiber bundles lateral to the thalamus and caudate nucleus and medial to the putamen and globus pallidus. It projects dorsally to the white matter underlying the cerebral cortex." [Wikipedia:Internal_capsule] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "internal capsule radiations" EXACT [] xref: FMA:61950 ! Internal capsule xref: GAID:685 ! internal capsule xref: MA:0002748 ! internal capsule xref: NIF_GrossAnatomy:birnlex_1659 ! Internal capsule xref: ncithesaurus:Internal_Capsule ! Internal Capsule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/91/Telencephalon-Horiconatal.jpg/200px-Telencephalon-Horiconatal.jpg xref: EMAPA:18206 ! internal capsule xref: MESH:A08.186.211.730.885.435 ! internal capsule xref: BM:IC ! internal capsule is_a: UBERON:0002437 ! cerebral white matter relationship: part_of UBERON:0001869 ! cerebral hemisphere synonym: "capsula interna" RELATED LATIN [Wikipedia:Internal_capsule] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Telencephalon-Horiconatal.jpg xref: UMLS:C0152341 [Term] id: UBERON:0013199 ! stria of neuraxis name: stria of neuraxis synonym: "neuraxis stria" EXACT [FMA:83854] synonym: "neuraxis striae" EXACT PLURAL [] synonym: "stria" BROAD [] synonym: "striae" BROAD PLURAL [] is_a: UBERON:0002316 ! white matter xref: FMA:83854 ! stria of neuraxis [Term] id: UBERON:0001889 name: trunk of phrenic nerve comment: This class was created automatically from a combination of ontologies synonym: "phrenic nerve trunk" EXACT [] synonym: "phrenic neural trunk" EXACT [] xref: FMA:6198 ! Trunk of phrenic nerve xref: MA:0001177 ! phrenic nerve trunk xref: EHDAA2:0001463 ! phrenic nerve trunk is_a: UBERON:0001147 ! trunk of peripheral nerve relationship: part_of UBERON:0001884 ! phrenic nerve [Term] id: UBERON:0002298 name: brainstem def: "Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,adopted]." [Wikipedia:Brainstem, ZFA:0001707, ISBN10:0471888893] comment: 'brainstem' is a loose term that sometimes refers to the ventral parts o the brain except for any part of the telencephalon - sometimes it includes the diencephalon or subpallial telencephalon structures (ISBN10:0471888893). Here we use it in a more restriced sense, to include only the medulla oblongata, pons (when present) and the midbrain tegmentum (following the ZFA definitions). subset: uberon_slim subset: vertebrate_core subset: loose_concept synonym: "brain stem" EXACT [ABA:BS] synonym: "truncus encephalicus" RELATED [BTO:0000146] xref: FMA:79876 ! Brainstem xref: VHOG:0001457 ! brainstem xref: MA:0000169 ! brainstem xref: NIF_GrossAnatomy:birnlex_1565 ! Brainstem xref: ZFA:0001707 ! brainstem xref: BTO:0000146 ! brain stem xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Gray719.png/200px-Gray719.png xref: MESH:A08.186.211.132 ! brain stem xref: EV:0100241 ! brain stem xref: ABA:BS ! Brain stem xref: EFO:0001962 ! brain stem is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: part_of UBERON:0000955 ! brain relationship: has_part UBERON:0001896 ! medulla oblongata relationship: has_part UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002037 {source="ABA"} ! cerebellum relationship: spatially_disjoint_from UBERON:0001890 {notes="we apply a strict definition"} ! forebrain relationship: spatially_disjoint_from UBERON:0002314 {notes="we apply a strict definition"} ! midbrain tectum relationship: continuous_with UBERON:0002240 ! spinal cord xref: ncithesaurus:Brain_Stem ! Brain Stem xref: SCTID:180925009 ! Entire brainstem xref: TAO:0002156 ! brainstem synonym: "truncus encephali" EXACT LATIN [Wikipedia:Brainstem] xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray719.png property_value: external_definition "Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002156", date_retrieved="2012-08-14", source="ISBN:3764351209"} xref: UMLS:C0006121 [Term] id: UBERON:0002028 name: hindbrain def: "The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]." [Wikipedia:Rhombencephalon, ZFIN:curator, ZFA:0000029] comment: in MA, brainstem and hindbrain and part-of siblings under brain, consistent with FMA and NIF. See also notes for cerebellum. We weaken the relation in ABA to overlaps subset: uberon_slim subset: vertebrate_core synonym: "rhombencephalon" RELATED [] xref: BTO:0000672 xref: EFO:0000923 ! hindbrain xref: EHDAA:3514 ! hindbrain xref: EHDAA:6487 ! hindbrain xref: FMA:67687 ! Hindbrain xref: VHOG:0000070 ! hindbrain xref: MA:0000195 ! hindbrain xref: MAT:0000107 ! hindbrain xref: MIAA:0000107 ! hindbrain xref: NIF_GrossAnatomy:birnlex_942 ! Hindbrain xref: TAO:0000029 ! hindbrain xref: XAO:0000015 ! hindbrain xref: ZFA:0000029 ! hindbrain xref: EHDAA2:0000746 ! hindbrain xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/54/EmbryonicBrain.svg/200px-EmbryonicBrain.svg.png xref: EMAPA:16916 ! hindbrain of brain of central nervous system of nervous system of organ system xref: MESH:A08.186.211.132.810 ! rhombencephalon xref: ABA:HB ! Hindbrain is_a: UBERON:0004732 ! segmental subdivision of nervous system relationship: develops_from UBERON:0003076 {source="XAO"} ! posterior neural tube relationship: overlaps UBERON:0002298 {source="ABA", notes="modified-source-relation"} ! brainstem relationship: part_of UBERON:0000955 {source="ZFA"} ! brain relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: spatially_disjoint_from UBERON:0001894 {source="ABA"} ! diencephalon relationship: spatially_disjoint_from UBERON:0001891 {source="ABA"} ! midbrain xref: ncithesaurus:Hind-Brain ! Hind-Brain xref: AAO:0010150 ! hindbrain relationship: has_developmental_contribution_from UBERON:0003852 {evidence="definitional"} ! rhombencephalon neural crest relationship: develops_from UBERON:0007277 {evidence="definitional"} ! presumptive hindbrain xref: http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg property_value: external_definition "Posterior part of the brain consisting of the cerebellum and medulla oblongata.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010150", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The most posterior of the three principal regions of the brain, forming the rhombencephalon and all or most of the metencephalon. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000029", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from hindbrain neural tube (TAO:0007043)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000029", date_retrieved="2012-08-14"} property_value: homology_notes "Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]" xsd:string {external_class="VHOG:0000070", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "rhombencephalic" xsd:string xref: UMLS:C0035507 [Term] id: UBERON:0002037 name: cerebellum def: "Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]." [BTO:0000232, MESH:A08.186.211.132.810.428.200, ZFA:0000100, ISBN:3764351209, https://sourceforge.net/tracker/index.php?func=detail&aid=3291162&group_id=76834&atid=1205376] comment: note that almost all AOs agree that the cerebellum is part of the hindbrain (sometimes specifically part of the metencephalon, which, when present, is part of the hindbrain). However, ABA has cerebellum and brain stem as partof siblings, with the hindbrain part of the brainstem subset: uberon_slim subset: vertebrate_core synonym: "epencephalon-1" EXACT [] xref: BTO:0000232 xref: EFO:0000327 ! cerebellum xref: FMA:67944 ! Cerebellum xref: GAID:595 ! cerebellum xref: VHOG:0000024 ! cerebellum xref: MA:0000198 ! cerebellum xref: MAT:0000110 ! cerebellum xref: MIAA:0000110 ! cerebellum xref: NIF_GrossAnatomy:birnlex_1489 ! Cerebellum xref: TAO:0000100 ! cerebellum xref: XAO:0003098 ! cerebellum xref: ZFA:0000100 ! cerebellum xref: ncithesaurus:Cerebellum ! Cerebellum xref: OpenCyc:Mx4rvl1eipwpEbGdrcN5Y29ycA ! cerebellum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Cerebellum_NIH.png/200px-Cerebellum_NIH.png xref: EMAPA:17787 ! cerebellum xref: MESH:A08.186.211.132.810.428.200 ! cerebellum xref: EV:0100293 ! cerebellum xref: ABA:CB ! Cerebellum xref: BM:CB ! cerebellum is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001895 {source="MA", source="FMA"} ! metencephalon relationship: part_of UBERON:0002028 {source="ZFA", source="NIF"} ! hindbrain relationship: spatially_disjoint_from UBERON:0002298 {source="ABA"} ! brainstem relationship: spatially_disjoint_from UBERON:0001893 {source="ABA"} ! telencephalon xref: AAO:0010485 ! cerebellum xref: SCTID:180924008 ! Entire cerebellum xref: EHDAA2:0000232 ! cerebellum relationship: develops_from UBERON:0006215 {evidence="definitional"} ! rhombic lip property_value: external_definition "Dorsal part of the hindbrain that coordinates muscle movement, posture, and balance.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010485", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Specialized brain region derived from the dorsal metencephalon (anterior hindbrain, and perhaps including posterior midbrain) and becoming distinctive late in the segmentation period. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000100", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "However, although the lamprey possesses a region comparable to the cerebellum and display expression of LjFgf8/17 at the MHB (midbrain hindbrain boundary), it does not have Purkinje cells and cerebellar nuclei, as well as components of the rhombic lip-derived cerebellar and pre-cerebellar systems. It is noteworthy that the latter structures require specific expression of Pax6 in the rhombic lip of the gnathostome hindbrain. Interestingly, the lamprey rhombic lip does not express Pax6. Thus, it is tempting to speculate that in vertebrate evolution the rostral hindbrain is incapable of differentiating into the cerebellum before the co-option of Pax6 in that region. In other words, cerebellum has been brought about as an evolutionary innovation in gnathostomes, based on exaptation of MHB, rhombic lip, and some regulatory gene expression already present in the vertebrate common ancestor.[well established][VHOG]" xsd:string {external_class="VHOG:0000024", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y\, Uchida K\, Rijli FM and Kuratani S\, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "cerebellar" xsd:string xref: UMLS:C0007765 [Term] id: UBERON:0001890 name: forebrain def: "The most anterior region the brain including both the telencephalon and diencephalon." [ZFIN:ZDB-PUB-961014-576, Wikipedia:Forebrain] subset: uberon_slim subset: vertebrate_core synonym: "prosencephalon" RELATED [] xref: BTO:0000478 xref: EFO:0000909 ! forebrain xref: EHDAA:3470 ! forebrain xref: FMA:61992 ! Forebrain xref: VHOG:0000383 ! forebrain xref: MA:0000170 ! forebrain xref: MAT:0000105 ! forebrain xref: MIAA:0000105 ! forebrain xref: NIF_GrossAnatomy:birnlex_1509 ! Forebrain xref: TAO:0000109 ! forebrain xref: XAO:0000011 ! forebrain xref: ZFA:0000109 ! forebrain xref: EHDAA2:0000556 ! forebrain xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/54/EmbryonicBrain.svg/200px-EmbryonicBrain.svg.png xref: EMAPA:16895 ! forebrain xref: MESH:A08.186.211.730 ! prosencephalon is_a: UBERON:0000481 ! multi-tissue structure relationship: develops_from UBERON:0003080 ! anterior neural tube relationship: immediate_transformation_of UBERON:0006240 {evidence="definitional"} ! future forebrain relationship: part_of UBERON:0000955 ! brain xref: ncithesaurus:Fore-Brain ! Fore-Brain xref: ncithesaurus:Prosencephalon ! Prosencephalon xref: AAO:0010147 ! forebrain xref: SCTID:362291003 ! Entire prosencephalon property_value: external_definition "Most anterior of the three regions of the brain consisting of the telencephalon and diencephalon.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010147", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The most anterior region the brain including both the telencephalon and diencephalon. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000109", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from forebrain neural tube (TAO:0007041)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000109", date_retrieved="2012-08-14"} property_value: homology_notes "In craniate embryos, neural expression of Distal-less-related genes is exclusively in the forebrain (...). Because the major neural expression domain of amphioxus AmphiDll is in the anterior three-fourths of the cerebral vesicle, we suggest that this region of the neural tube is homologous to parts of the craniate forebrain. This conclusion is strongly supported by three-dimensional, computer-assisted reconstruction of the neural tube of amphioxus based on serial transmission electron microscopy. At the neuroanatomical level, a number of detailed homologies are indicated between the anterior three-fourths of the amphioxus cerebral vesicle and the diencephalic region of the craniate forebrain. If one assumes that the amphioxus condition fairly represents the nervous system of the proximate ancestor of the craniates, one can suggest that they evolved from a creature that had the beginnings of a forebrain.[well established][VHOG]" xsd:string {external_class="VHOG:0000383", ontology="VHOG", source="PMID:8787764 Holland ND\, Panganiban G\, Henyey EL\, Holland LZ\, Sequence and developmental expression of AmphiDll\, an amphioxus Distal-less gene transcribed in the ectoderm\, epidermis and nervous system: insights into evolution of craniate forebrain and neural crest. Development (1996)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "prosencephalic" xsd:string xref: UMLS:C0085140 [Term] id: UBERON:0001891 name: midbrain def: "Organ component of neuraxis that has as its parts the tectum, cerebral peduncle, midbrain tegmentum and cerebral aqueduct[FMA]. The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally[ZFA]. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]." [Wikipedia:Midbrain, ZFIN:curator, GO:0030901, FMA:61993] comment: Editors note: developmental relationships need revised. AO notes: part of brainstem in ABA - we reject this in favor of ISBN10:0471888893 which has an implicit overlaps relationships subset: uberon_slim subset: vertebrate_core synonym: "mesencephalon" RELATED [] xref: BTO:0000138 xref: EFO:0000919 ! midbrain xref: EHDAA:3694 ! midbrain xref: FMA:61993 ! Midbrain xref: VHOG:0000069 ! midbrain xref: MA:0000207 ! midbrain xref: MAT:0000106 ! midbrain xref: MIAA:0000106 ! midbrain xref: NIF_GrossAnatomy:birnlex_1667 ! Midbrain xref: TAO:0000128 ! midbrain xref: XAO:0000014 ! midbrain xref: ZFA:0000128 ! midbrain xref: RETIRED_EHDAA2:0001104 ! mesencephalon xref: EHDAA2:0001162 ! midbrain xref: OpenCyc:Mx4rvsBUqpwpEbGdrcN5Y29ycA ! midbrain xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f9/Human_brain_inferior_view_description.JPG/200px-Human_brain_inferior_view_description.JPG xref: EMAPA:16974 ! midbrain xref: MESH:A08.186.211.132.659 ! mesencephalon xref: EV:0100242 ! midbrain xref: ABA:MB ! Midbrain xref: BM:MB ! midbrain is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000955 ! brain relationship: spatially_disjoint_from UBERON:0002028 {source="ABA"} ! hindbrain relationship: spatially_disjoint_from UBERON:0001894 {source="ABA"} ! diencephalon relationship: has_developmental_contribution_from UBERON:0003849 {evidence="definitional"} ! mesencephalic neural crest relationship: develops_from UBERON:0009616 {evidence="definitional"} ! presumptive midbrain xref: ncithesaurus:Mesencephalon ! Mesencephalon xref: AAO:0010149 ! midbrain xref: SCTID:279099009 ! Entire midbrain synonym: "mesencephalon" RELATED LATIN [Wikipedia:Midbrain] xref: http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG property_value: external_definition "Middle part of the brain composed of the optic tectum and penducular region.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010149", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000128", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]" xsd:string {external_class="VHOG:0000069", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "mesencephalic" xsd:string xref: UMLS:C0025462 [Term] id: UBERON:0001893 name: telencephalon def: "Organ component of neuraxis that has as its parts the cerebral cortex, cerebral white matter, basal ganglia, septum and fornix, as well as subcortical gray and white matter structures[FMA]." [Wikipedia:Telencephalon, FMA:62000] comment: The telencephalon is the name for a large region within the brain that is attributed many functions. Many people refer to it as the cerebrum; however, it is technically referred to as the telencephalon. As a more technical definition, the telencephalon refers to the cerebral hemispheres and other, smaller structures within the brain, although the telencephalon is one of the larger divisions (in terms of number). It is the anterior-most embryological division of the brain that develops from the prosencephalon. The telencephalon is composed of the following sub-regions; Limbic system; Cerebral cortex or cortices of the cerebral hemispheres, Basal ganglia, Olfactory bulb. The telencephalon comprises what most people think of as the 'brain' It lies on top of the brainstem and is the largest and most well-developed of the five major divisions of the brain. The telencephalon is the newest structure in the phylogenetic sense, with mammals having the largest and most well-developed among all species. It emerges from the prosencephalon, the first of three vesicles that form from the embryonic neural tube (Christine Fennema-Notestine, NIF_GrossAnatomy:birnlex_1115). subset: uberon_slim subset: vertebrate_core synonym: "endbrain" EXACT [Swanson:2004] synonym: "cerebrum" EXACT [http://en.wikipedia.org/wiki/Talk:Cerebrum] xref: BTO:0000239 xref: EFO:0000912 ! telencephalon xref: FMA:62000 ! Telencephalon xref: GAID:621 ! telencephalon xref: VHOG:0000283 ! telencephalon xref: MA:0000183 ! telencephalon xref: MAT:0000421 ! telencephalon xref: MIAA:0000421 ! telencephalon xref: NIF_GrossAnatomy:birnlex_1115 ! Telencephalon xref: TAO:0000079 ! telencephalon xref: XAO:0000012 ! telencephalon xref: ZFA:0000079 ! telencephalon xref: EHDAA2:0001982 ! telencephalon xref: EMAPA:16652 ! telencephalon of future forebrain xref: EMAPA:16910 ! telencephalon of forebrain xref: MESH:A08.186.211.730.885 ! telencephalon xref: EV:0100165 ! cerebrum xref: ABA:CH ! Cerebrum xref: BM:Tel ! telencephalon is_a: UBERON:0002780 ! regional part of forebrain relationship: part_of UBERON:0001890 ! forebrain relationship: spatially_disjoint_from UBERON:0002037 {source="ABA"} ! cerebellum xref: AAO:0010479 ! telencephalon xref: SCTID:263353005 ! Entire cerebrum relationship: has_developmental_contribution_from UBERON:0003850 {evidence="definitional"} ! telencephalon neural crest property_value: external_definition "Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010479", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The anterior and dorsal forebrain neuromere, includes the olfactory bulb. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000079", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from presumptive telencephalon (TAO:0000571)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000079", date_retrieved="2012-08-14"} property_value: homology_notes "From an evolutionary standpoint, the telencephalon is the most recent brain structure: the amphioxus does not have this structure as a morphological entity. Overt telencephalon is present in the hagfish and lamprey to receive numerous input fibers from various parts of the CNS, similar to gnathostomes.[well established][VHOG]" xsd:string {external_class="VHOG:0000283", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y\, Uchida K\, Rijli FM and Kuratani S\, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "cerebral" xsd:string property_value: has_relational_adjective "telenencephalic" xsd:string property_value: taxon_notes "In the most primitive living vertebrates, the hagfishes and lampreys, the cerebrum is a relatively simple structure receiving nerve impulses from the olfactory bulb." xsd:string {source="http://en.wikipedia.org/wiki/Telencephalon#Variation_among_species"} property_value: taxon_notes "In ray-finned fishes the inner surfaces of the lateral and ventral regions of the cerebrum bulge up into the ventricles." xsd:string {source="http://en.wikipedia.org/wiki/Telencephalon#Variation_among_species"} property_value: taxon_notes "In the amniotes, the cerebrum becomes increasingly large and complex. In reptiles, the paleopallium is much larger than in amphibians, and its growth has pushed the basal nuclei into the central regions of the cerebrum." xsd:string {source="http://en.wikipedia.org/wiki/Telencephalon#Variation_among_species"} property_value: taxon_notes "The cerebrum of birds has evolved along different lines to that of mammals, although they are similarly enlarged, by comparison with reptiles. However, this enlargement is largely due to the basal ganglia, with the other areas remaining relatively primitive in structure." xsd:string {source="http://en.wikipedia.org/wiki/Telencephalon#Variation_among_species"} property_value: taxon_notes "In mammals the cortex covers almost the whole of the cerebral hemispheres." xsd:string {source="http://en.wikipedia.org/wiki/Telencephalon#Variation_among_species"} property_value: taxon_notes "dolphins are the only species (other than humans) to have cerebra accounting for as much as 2 percent of their body weight." xsd:string {source="http://en.wikipedia.org/wiki/Telencephalon#Variation_among_species"} [Term] id: UBERON:0001894 name: diencephalon def: "Organ component of neuraxis that has as its parts the epithalamus, thalamus, hypothalamus, subthalamus[FMA]. The more posterior and ventral of two forebrain neuromeres, the other being the telencephalon; major derivatives are the eye cups, the brain pretectal region, the thalamus, hypothalamus, and epithalamus (including the habenula and epiphysis). Kimmel et al, 1995." [Wikipedia:Diencephalon, ZFIN:curator, FMA:62001] comment: Note that in ABA, this is part of the brain stem subset: uberon_slim subset: vertebrate_core synonym: "between brain" EXACT [] synonym: "interbrain" EXACT [Swanson:2004] synonym: "mature diencephalon" EXACT [FMA:62001] synonym: "betweenbrain" RELATED [BTO:0000342] xref: BTO:0000342 xref: EFO:0000911 ! diencephalon xref: EHDAA:1969 ! diencephalon xref: EHDAA:2645 ! diencephalon xref: EHDAA:3472 ! diencephalon xref: FMA:62001 ! Diencephalon xref: GAID:618 ! diencephalon xref: VHOG:0000318 ! diencephalon xref: MA:0000171 ! diencephalon xref: MAT:0000420 ! diencephalon xref: MIAA:0000420 ! diencephalon xref: NIF_GrossAnatomy:birnlex_1503 ! Diencephalon xref: TAO:0000101 ! diencephalon xref: XAO:0000013 ! diencephalon xref: ZFA:0000101 ! diencephalon xref: ncithesaurus:Diencephalon ! Diencephalon xref: OpenCyc:Mx4rwC-V0JwpEbGdrcN5Y29ycA ! diencephalon xref: EHDAA2:0000385 ! diencephalon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/54/EmbryonicBrain.svg/200px-EmbryonicBrain.svg.png xref: EMAPA:16641 ! diencephalon of future forebrain xref: EMAPA:16896 ! diencephalon of forebrain xref: MESH:A08.186.211.730.385 ! diencephalon xref: EV:0100194 ! diencephalon xref: ABA:IB ! Interbrain xref: BM:Die ! diencephalon is_a: UBERON:0002780 ! regional part of forebrain relationship: part_of UBERON:0001890 ! forebrain relationship: spatially_disjoint_from UBERON:0002028 {source="ABA"} ! hindbrain relationship: spatially_disjoint_from UBERON:0001891 {source="ABA"} ! midbrain xref: AAO:0010481 ! diencephalon xref: SCTID:279328001 ! Entire diencephalon relationship: has_developmental_contribution_from UBERON:0003851 {evidence="definitional"} ! diencephalon neural crest relationship: immediate_transformation_of UBERON:0006222 {evidence="definitional"} ! future diencephalon synonym: "diencephalon" RELATED LATIN [Wikipedia:Diencephalon] xref: http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg property_value: external_definition "Unpaired part of the forebrain comprised of three major parts; the epithalamus, thalamus, and hypothalamus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010481", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The more posterior and ventral of two forebrain neuromeres, the other being the telencephalon; major derivatives are the eye cups, the brain pretectal region, the thalamus, hypothalamus, and epithalamus (including the habenula and epiphysis). Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000101", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]" xsd:string {external_class="VHOG:0000318", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "diencephalic" xsd:string xref: UMLS:C0012144 [Term] id: UBERON:0010092 name: future metencephalon is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002028 ! hindbrain intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: develops_into UBERON:0001895 ! metencephalon xref: EHDAA2:0000623 ! future metencephalon def: "A developing anatomical structure that develops_into a metencephalon." [OBOL:automatic] [Term] id: UBERON:0001895 name: metencephalon def: "Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum." [Wikipedia:Metencephalon] comment: the terms metencephalon and myelencephalon are only meaningful in mammals and birds[Neuroanatomy of the Zebrafish Brain]. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata and thus these are not distinguished in ZFA[ZFA]. subset: uberon_slim synonym: "epencephalon-2" RELATED [FMA:62003] synonym: "epencephalon" EXACT [ncithesaurus:Epencephalon] xref: BTO:0000673 xref: EHDAA:5498 ! metencephalon xref: FMA:62003 ! Metencephalon xref: GAID:594 ! metencephalon xref: VHOG:0000741 ! metencephalon xref: MA:0000197 ! metencephalon xref: NIF_GrossAnatomy:birnlex_965 ! Metencephalon xref: EHDAA2:0001149 ! metencephalon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/54/EmbryonicBrain.svg/200px-EmbryonicBrain.svg.png xref: EMAPA:17071 ! metencephalon xref: MESH:A08.186.211.132.810.428 ! metencephalon is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0002028 ! hindbrain relationship: dubious_for_taxon NCBITaxon:7955 ! Danio rerio relationship: immediate_transformation_of UBERON:0010092 {evidence="definitional"} ! future metencephalon xref: ncithesaurus:Epencephalon ! Epencephalon xref: http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg property_value: external_definition "The anterior of two brain vesicles formed by specialization of the rhombencephalon in the developing embryo. It gives rise to cerebellum and pons. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000741", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/metencephalon", source="http://bgee.unil.ch/"} property_value: homology_notes "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000741", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.381-382\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1516904 [Term] id: UBERON:0010096 name: future myelencephalon is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002028 ! hindbrain intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: develops_into UBERON:0005290 ! myelencephalon xref: EHDAA2:0000640 ! future myelencephalon def: "A developing anatomical structure that develops_into a myelencephalon." [OBOL:automatic] [Term] id: UBERON:0005290 name: myelencephalon def: "The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]." [Wikipedia:Myelencephalon, BTO:0000758] comment: the terms metencephalon and myelencephalon are only meaningful in mammals and birds - Neuroanatomy of the Zebrafish Brain. Note that its not clear if this refers to the developing medulla oblongata - MA (adult) has two distinct classes subset: uberon_slim xref: BTO:0000758 ! myelencephalon xref: EHDAA2:0001207 ! myelencephalon xref: EHDAA:5526 ! myelencephalon xref: EMAPA:17082 ! myelencephalon xref: VHOG:0000456 ! myelencephalon xref: MA:0000205 ! myelencephalon xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/54/EmbryonicBrain.svg/200px-EmbryonicBrain.svg.png is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0002028 ! hindbrain relationship: dubious_for_taxon NCBITaxon:7955 ! Danio rerio relationship: immediate_transformation_of UBERON:0010096 {evidence="definitional"} ! future myelencephalon xref: http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg property_value: external_definition "The posterior of the two brain vesicles formed by specialization of the rhombencephalon in the developing embryo, it comprises the medulla oblongata. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000456", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/myelencephalon", source="http://bgee.unil.ch/"} property_value: homology_notes "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000456", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.381-382\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001896 name: medulla oblongata def: "Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]." [FMA:62004, GO:0021550, Wikipedia:Bone_marrow_of_ovary_oblongata] subset: uberon_slim subset: vertebrate_core synonym: "bulb" BROAD [] synonym: "metepencephalon" RELATED [FMA:62004] synonym: "medulla" BROAD [ABA:MY] xref: ABA:MY ! Medulla xref: BTO:0000041 ! medulla oblongata xref: EFO:0000924 ! medulla oblongata xref: EHDAA:7588 ! medulla oblongata xref: FMA:62004 ! Medulla oblongata xref: GAID:590 ! medulla oblongata xref: VHOG:0000181 ! medulla oblongata xref: MA:0000206 ! medulla oblongata xref: MAT:0000111 ! medulla oblonmgata xref: MAT:0000367 ! bulb xref: MIAA:0000111 ! medulla oblonmgata xref: NIF_GrossAnatomy:birnlex_957 ! Medulla oblongata xref: OpenCyc:Mx4rvVjxSJwpEbGdrcN5Y29ycA xref: TAO:0000545 ! medulla oblongata xref: XAO:0003100 ! medulla oblongata xref: ZFA:0000545 ! medulla oblongata xref: ncithesaurus:Medulla_Oblongata ! Medulla Oblongata xref: OpenCyc:Mx4rwCqnXJwpEbGdrcN5Y29ycA ! medulla oblongata xref: EHDAA2:0001088 ! medulla oblongata (also: UBERON:0010288 'future medulla oblongata') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Illu_pituitary_pineal_glands.jpg/200px-Illu_pituitary_pineal_glands.jpg xref: EMAPA:17550 ! medulla oblongata xref: MESH:A08.186.211.132.810.406 ! medulla oblongata xref: EV:0100275 ! medulla oblongata is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002298 ! brainstem relationship: capable_of GO:0002027 ! regulation of heart rate relationship: capable_of GO:0043576 ! regulation of respiratory gaseous exchange relationship: capable_of GO:0044058 ! regulation of digestive system process relationship: part_of UBERON:0005290 ! myelencephalon relationship: spatially_disjoint_from UBERON:0000988 {source="ABA"} ! pons synonym: "bulbus" EXACT LATIN [FMA:TA, FMA:62004] xref: AAO:0010486 ! medulla oblongata xref: SCTID:279104005 ! Entire medulla oblongata synonym: "medulla oblonzata" RELATED LATIN [Wikipedia:Medulla_oblongata] property_value: external_definition "Posterior portion of the hindbrain which controls respiration, heartbeat, digestion, and swallowing as well as some locomotor responses.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010486", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The posterior region of the brain that is continuous with the spinal cord. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-17, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000181", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Classical anatomical studies subdivided the vertebrate rhombencephalon into pons and medulla oblongata. (...) The medulla oblongata appears therefore as a tagma, that is, a group of segmental units (pseudorhombomeres, in this case) sharing some morphological and molecular characteristics, and in some aspects different from the segmental units present in adjoining brain regions, pons and spinal cord.[well established][VHOG]" xsd:string {external_class="VHOG:0000181", ontology="VHOG", source="DOI:10.1016/j.ydbio.2008.08.017 Marin F\, Aroca P\, Puelles L\, Hox gene colinear expression in the avian medulla oblongata is correlated with pseudorhombomeric domains. Developmental Biology (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0025148 [Term] id: UBERON:0005807 name: rostral ventrolateral medulla def: "Control of blood pressure is crucially dependent on the integrity of a small region of the brainstem called the ventrolateral medulla. Within this part of the brain are the cells that control the heart, blood vessels, swallowing, breathing and many other functions of the body that are not noticed at a conscious level; such unconscious activities are known as 'Autonomic'. One of these regions is the Rostral Ventrolateral Medulla (RVLM) is also known as the pressor area of the medulla (medulla pressor). It receives inhibitory GABAergic input from the caudal ventrolateral medulla (CVLM). The RVLM is the primary regulator of the sympathetic nervous system, sending excitatory fibers (catecholaminergic) to the sympathetic preganglionic neurons in the spinal cord, via reticulospinal tract[WP]." [Wikipedia:Rostral_ventrolateral_medulla] synonym: "RVLM" EXACT [] synonym: "medulla pressor" EXACT [Wikipedia:Rostral_ventrolateral_medulla] xref: BTO:0002778 ! rostral ventrolateral medulla is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001896 ! medulla oblongata relationship: has_function_in GO:0008217 {source="Wikipedia"} ! control of blood pressure [Term] id: UBERON:0004703 name: dorsal thalamus comment: MA and ZFA think there is a distinct dorsal thalamus, but FMA says its an exact synonym. TODO. http://www.ncbi.nlm.nih.gov/pubmed/8167659 subset: vertebrate_core synonym: "dorsal thalamus" RELATED [FMA:62007] synonym: "thalamus, pars dorsalis" EXACT [ZFA:0000653] xref: ZFA:0000653 ! dorsal thalamus xref: MA:0000180 ! dorsal thalamus xref: BM:Die-Th ! dorsal thalamus is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001897 ! thalamus xref: ncithesaurus:Dorsal_Thalamus ! Dorsal Thalamus xref: EHDAA2:0000692 ! dorsal thalamus xref: TAO:0000653 ! dorsal thalamus [Term] id: UBERON:0010225 ! thalamic complex name: thalamic complex is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001894 {source="EHDAA2"} ! diencephalon xref: EHDAA2:0004469 ! thalamic complex xref: FMA:258745 ! thalamic complex [Term] id: UBERON:0001897 name: thalamus def: "A midline paired symmetrical structure within the brains of vertebrates, including humans. It is situated between the cerebral cortex and midbrain, both in terms of location and neurological connections. Its function includes relaying sensation, special sense and motor signals to the cerebral cortex, along with the regulation of consciousness, sleep and alertness. The thalamus surrounds the third ventricle. It is the main product of the embryonic diencephalon." [Wikipedia:Thalamus] comment: AO notes: MA and ZFA think there is a distinct dorsal thalamus, but FMA says its an exact synonym. FMA has a distinct class for thalamic complex. subset: uberon_slim subset: vertebrate_core synonym: "dorsal thalamus" RELATED [FMA:62007] synonym: "dorsal thalamus (anthoney)" EXACT [FMA:62007] synonym: "thalamus dorsalis" RELATED [BTO:0001365] xref: BTO:0001365 xref: EFO:0000910 ! thalamus xref: FMA:62007 ! Thalamus xref: GAID:656 ! thalamus xref: VHOG:0000657 ! thalamus xref: MA:0000179 ! thalamus xref: MAT:0000109 ! thalamus xref: MIAA:0000109 ! thalamus xref: NIF_GrossAnatomy:birnlex_954 ! Thalamus xref: TAO:0001215 ! thalamus xref: ZFA:0001215 ! thalamus xref: ncithesaurus:Thalamus ! Thalamus xref: galen:Thalamus ! thalamus xref: OpenCyc:Mx4rwMPQ65wpEbGdrcN5Y29ycA ! thalamus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/ce/Brain_chrischan_thalamus.jpg/200px-Brain_chrischan_thalamus.jpg xref: EMAPA:17540 ! thalamus xref: MESH:A08.186.211.730.385.826 ! thalamus xref: EV:0100195 ! thalamus xref: ABA:TH ! Thalamus is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0010225 ! thalamic complex relationship: spatially_disjoint_from UBERON:0001898 {source="ABA"} ! hypothalamus xref: AAO:0010483 ! thalamus xref: SCTID:244433007 ! Entire thalamus synonym: "thalamus dorsalis" RELATED LATIN [Wikipedia:Thalamus] xref: http://upload.wikimedia.org/wikipedia/commons/c/ce/Brain_chrischan_thalamus.jpg property_value: external_definition "Part of the diencephalon consisting of a mass of connecting fibers which relay sensory information to the cerebral cortex.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010483", date_retrieved="2012-06-20", source="AAO:BJB"} synonym: "thalami" RELATED PLURAL [VHOG:0000657] property_value: external_definition "One of a pair of large oval nervous structures made of gray matter and forming most of the lateral walls of the third ventricle of the brain and part of the diencephalon. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000657", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/thalamus", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the brain regions of tetrapods, the structures they contain, and their basic organizational features are the same as in fishes.[well established][VHOG]" xsd:string {external_class="VHOG:0000657", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.484", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} relationship: in_lateral_side_of UBERON:0010225 {source="FMA-abduced-lr"} ! thalamic complex property_value: has_relational_adjective "thalamic" xsd:string xref: UMLS:C0039729 [Term] id: UBERON:0001898 name: hypothalamus def: "A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]." [Wikipedia:Hypothalamus, ZFIN:curator] comment: Taxon notes: all vertebrates contain a hypothalamus[WP]. subset: uberon_slim subset: vertebrate_core synonym: "preoptico-hypothalamic area" EXACT [] synonym: "preoptico-hypothalamic region" EXACT [] xref: BTO:0000614 xref: EFO:0000107 ! hypothalamus xref: EHDAA:5446 ! hypothalamus xref: FMA:62008 ! Hypothalamus xref: GAID:460 ! hypothalamus xref: galen:Hypothalamus xref: VHOG:0000179 ! hypothalamus xref: MA:0000173 ! hypothalamus xref: MAT:0000112 ! hypothalamus xref: MIAA:0000112 ! hypothalamus xref: NIF_GrossAnatomy:birnlex_734 ! Hypothalamus xref: TAO:0000032 ! hypothalamus xref: ZFA:0000032 ! hypothalamus xref: ncithesaurus:Hypothalamus ! Hypothalamus xref: OpenCyc:Mx4rwEgr9JwpEbGdrcN5Y29ycA ! hypothalamus xref: EHDAA2:0000802 ! hypothalamus xref: EMAPA:17536 ! hypothalamus xref: MESH:A08.186.211.577.482 ! hypothalamus xref: EV:0100225 ! hypothalamus xref: ABA:HY ! Hypothalamus xref: BM:Die-Hy ! hypothalamus is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000349 ! limbic system relationship: part_of UBERON:0001894 ! diencephalon relationship: spatially_disjoint_from UBERON:0001897 {source="ABA"} ! thalamus relationship: capable_of GO:0046883 {source="WP"} ! regulation of hormone secretion relationship: capable_of GO:0060986 ! endocrine hormone secretion xref: AAO:0010484 ! hypothalamus xref: SCTID:264483005 ! Entire hypothalamus xref: XAO:0004070 ! hypothalamus synonym: "hypothalamus" RELATED LATIN [Wikipedia:Hypothalamus] xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/LocationOfHypothalamus.jpg property_value: external_definition "Part of the diencephalon ventral to the thalamus consisting of connecting fibers and is a center for control of the autonomous nervous system.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010484", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000032", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "For instance, the vertebrate ventral diencephalon generates the hypothalamus which functions as a major endocrine center in cooperation with the hypophysis, the anterior part of the pituitary gland, located just ventral to the hypothalamus. In the amphioxus brain, the presence of a hypothalamus-like structure has been reported associated with the ventrally located Hatschek's pit, the hypothetical hypophysial homologue. It is thus conceivable that a hypothalamus-like structure originally involved in endocrine functions may have already been present before the establishment of vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000179", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y\, Uchida K\, Rijli FM and Kuratani S\, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "hypothalamic" xsd:string xref: UMLS:C0020663 [Term] id: UBERON:0009976 name: hypothalamo-hypophyseal system def: "An intrinsic circulatory network that transports hormones from the median eminence of the hypothalamus to the adenohypophysis." [ISBN10:0471888893, Wikipedia:Hypophyseal_portal_system] comment: Taxon notes: in lampreys and teleost hormones enter the adenohypophysis by diffusion. Editor notes: we represent this structure strictly as a system of blood vessels (presumably in line with the FMA). It could also be extended to include neurons and fiber tracts, as per the MESH definition. Function notes: One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis). The hypothalamus is responsible for certain metabolic processes and other activities of the autonomic nervous system. It synthesizes and secretes certain neurohormones, often called hypothalamic-releasing hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones. The hypothalamus controls body temperature, hunger, thirst, fatigue, sleep, and circadian cycles[WP] synonym: "hypothalamohypophyseal portal system" EXACT [] synonym: "hypothalamic hypophyseal portal system" EXACT [ISBN10:0471888893] synonym: "hypothalamo hypophyseal system" RELATED [MESH:A06.407.747.357] synonym: "hypothalamo-hypophyseal system" RELATED [MESH:A06.407.747.357] synonym: "hypophyseal portal system" EXACT [Wikipedia:Hypophyseal_portal_system] synonym: "venae portales hypophysiales" EXACT [Wikipedia:Hypophyseal_portal_system] synonym: "venae portales hypophysiales" RELATED LATIN [Wikipedia:Hypophyseal_portal_system] is_a: UBERON:0005806 ! portal system relationship: connects UBERON:0001898 ! hypothalamus relationship: connects UBERON:0002197 ! median eminence of neurohypophysis relationship: connects UBERON:0002196 ! adenohypophysis relationship: part_of UBERON:0000949 ! endocrine system relationship: never_in_taxon NCBITaxon:32443 {source="ISBN10:0471888893"} ! Teleostei xref: MESH:A06.407.747.357 ! hypothalamo-hypophyseal system xref: FMA:70860 ! set of portal veins of hypophysis xref: ncithesaurus:Hypothalamohypophyseal_Portal_System ! hypothalamohypophyseal portal system synonym: "set of portal veins of hypophysis" RELATED [FMA:70860] synonym: "portal veins of hypophysis" RELATED [FMA:70860] xref: UMLS:C1512570 [Term] id: UBERON:0001899 name: epithalamus def: "The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle[GO]. a dorsal posterior segment of the diencephalon (a segment in the middle of the brain also containing the hypothalamus and the thalamus) which includes the habenula, the stria medullaris and the pineal body. Its function is the connection between the limbic system to other parts of the brain[WP] Some functions of its components include the secretion of melatonin by the pineal gland. " [Wikipedia:Epithalamus] subset: uberon_slim subset: vertebrate_core xref: BTO:0000175 xref: EFO:0000918 ! epithalamus xref: EHDAA:5433 ! epithalamus xref: FMA:62009 ! Epithalamus xref: GAID:455 ! epithalamus xref: VHOG:0000178 ! epithalamus xref: MA:0000172 ! epithalamus xref: MAT:0000422 ! epithalamus xref: MIAA:0000422 ! epithalamus xref: NIF_GrossAnatomy:birnlex_1710 ! Epithalamus xref: TAO:0000509 ! epithalamus xref: ZFA:0000509 ! epithalamus xref: ncithesaurus:Epithalamus ! Epithalamus xref: OpenCyc:Mx4rvneLQpwpEbGdrcN5Y29ycA ! epithalamus xref: EHDAA2:0000448 ! epithalamus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Epithalamus.png/200px-Epithalamus.png xref: EMAPA:17532 ! epithalamus xref: MESH:A08.186.211.577.200 ! epithalamus xref: EV:0100220 ! epithalamus xref: ABA:EPI ! Epithalamus xref: BM:Die-Epi ! epithalamus is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001894 ! diencephalon relationship: spatially_disjoint_from UBERON:0002733 {source="ABA"} ! intralaminar nuclear group relationship: spatially_disjoint_from UBERON:0002736 {source="ABA"} ! lateral nuclear group relationship: spatially_disjoint_from UBERON:0001903 {source="ABA"} ! thalamic reticular nucleus xref: AAO:0010482 ! epithalamus xref: SCTID:281487003 ! Entire epithalamus synonym: "epithalamus" RELATED LATIN [Wikipedia:Epithalamus] xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Epithalamus.png property_value: external_definition "Dorsal segment of the diencephalon containing the habenular ganglia, a choroid plexus, and the pineal organ.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010482", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The roof of the diencephalon lying above the thalamus. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-11, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000178", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The epithalamus has been historically conceived as a distinct neuroanatomical moiety within the diencephalon of all vertebrates. (...) The evolutionary origins of epithalamic structures are uncertain but asymmetry in this region is likely to have existed at the origin of the vertebrate, perhaps even the chordate, lineage.[well established][VHOG]" xsd:string {external_class="VHOG:0000178", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910063.x Concha ML and Wilson SW\, Asymmetry in the epithalamus of vertebrates. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "epithalamic" xsd:string xref: UMLS:C0152361 [Term] id: UBERON:0001900 name: subthalamus def: "Anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis[GO]." [GO:0021539, Wikipedia:Subthalamus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "prethalamus" EXACT DEVELOPMENTAL [] synonym: "subthalamic region" EXACT [] synonym: "ventral thalamus" EXACT [] synonym: "thalamus ventralis" EXACT [NIF_GrossAnatomy:birnlex_708] xref: FMA:62010 ! Subthalamus xref: GAID:653 ! subthalamus xref: MA:0000181 ! ventral thalamus xref: NIF_GrossAnatomy:birnlex_708 ! Subthalamus xref: TAO:0000458 ! ventral thalamus xref: ZFA:0000458 ! ventral thalamus xref: ncithesaurus:Ventral_Thalamus ! Ventral Thalamus xref: MESH:A08.186.211.730.385.800 ! subthalamus xref: EV:0100223 ! subthalamus xref: BM:Die-VTh ! ventral thalamus is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001897 {source="MA"} ! thalamus xref: SCTID:279332007 ! Entire subthalamus xref: EHDAA2:0004470 ! subthalamus property_value: has_relational_adjective "subthalamic" xsd:string xref: UMLS:C0152349 [Term] id: UBERON:0001901 name: epithelium of trachea alt_id: UBERON:0003227 comment: This class was created automatically from a combination of ontologies synonym: "trachea epithelium" EXACT [] synonym: "tracheal epithelium" EXACT [] synonym: "epithelial tissue of trachea" EXACT [OBOL:automatic] synonym: "epithelial tissue of windpipe" EXACT [OBOL:automatic] synonym: "epithelium of windpipe" EXACT [OBOL:automatic] synonym: "trachea epithelial tissue" EXACT [OBOL:automatic] synonym: "windpipe epithelial tissue" EXACT [OBOL:automatic] synonym: "windpipe epithelium" EXACT [OBOL:automatic] xref: BTO:0001389 xref: FMA:62015 ! Epithelium of trachea xref: VHOG:0001045 ! trachea epithelium xref: MA:0001862 ! trachea epithelium xref: EHDAA:5007 ! epithelium xref: ncithesaurus:Tracheal_Epithelium ! Tracheal Epithelium xref: EHDAA2:0002069 ! trachea epithelium xref: EMAPA:16855 ! epithelium of trachea xref: EMAPA:18409 ! epithelium of carina tracheae is_a: UBERON:0000485 ! simple columnar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0003258 ! endoderm of foregut def: "An epithelium that is part of a trachea." [OBOL:automatic] xref: UMLS:C1179002 [Term] id: UBERON:0001902 name: epithelium of small intestine def: "An epithelium that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "small intestinal epithelium" EXACT [] synonym: "small intestine epithelium" EXACT [] synonym: "epithelial tissue of small bowel" EXACT [OBOL:automatic] synonym: "epithelial tissue of small intestine" EXACT [OBOL:automatic] synonym: "epithelium of small bowel" EXACT [OBOL:automatic] synonym: "small bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "small bowel epithelium" EXACT [OBOL:automatic] synonym: "small intestine epithelial tissue" EXACT [OBOL:automatic] synonym: "mid intestine epithelium" EXACT [ZFA:0005127] xref: BTO:0001258 xref: FMA:62017 ! Epithelium of small intestine xref: MA:0001553 ! small intestine epithelium xref: ZFA:0005127 ! mid intestine epithelium is_a: UBERON:0001277 ! intestinal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001204 ! mucosa of small intestine relationship: has_part CL:0000164 {source="FMA"} ! enteroendocrine cell xref: SCTID:45480009 ! Small intestine epithelium xref: TAO:0005127 ! mid intestine epithelium property_value: external_definition "Intestinal epithelium which lines the lumen of the mid intestine.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005127", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0001903 name: thalamic reticular nucleus def: "The thalamic reticular nucleus is part of the ventral thalamus that forms a capsule around the thalamus laterally. It is separated from the thalamus by the external medullary lamina. Reticular cells are GABAergic, and have discoid dendritic arbors in the plane of the nucleus. Thalamic Reticular Nucleus is variously abbreviated TRN, RTN, NRT, and RT. [WP,unvetted]." [Wikipedia:Thalamic_reticular_nucleus] comment: AO notes: only MA considers this part of a subthalamus; MA also considers a subthalamus part of a thalamus subset: uberon_slim synonym: "reticular nuclear group" EXACT [] synonym: "reticular nucleus of thalamus" EXACT [] synonym: "reticular nucleus of the thalamus" EXACT [] synonym: "reticular nucleus-2" EXACT [] synonym: "reticular thalamic nucleus" EXACT [] xref: FMA:62026 ! Thalamic reticular nucleus xref: MA:0000876 ! reticular thalamic nucleus xref: NIF_GrossAnatomy:birnlex_1721 ! Thalamic reticular nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Constudthal.gif/200px-Constudthal.gif xref: EV:0100214 ! reticular thalamic nucleus xref: ABA:RT ! Reticular nucleus of the thalamus xref: BM:Die-VTh-R ! reticular nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001900 {source="MA"} ! subthalamus relationship: spatially_disjoint_from UBERON:0001899 {source="ABA"} ! epithalamus relationship: spatially_disjoint_from UBERON:0002733 {source="ABA"} ! intralaminar nuclear group relationship: spatially_disjoint_from UBERON:0002736 {source="ABA"} ! lateral nuclear group synonym: "nucleus reticularis thalami" EXACT LATIN [FMA:TA, FMA:62026] xref: SCTID:279164008 ! Entire thalamic reticular nucleus synonym: "nucleus reticularis thalami" RELATED LATIN [Wikipedia:Thalamic_reticular_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Constudthal.gif [Term] id: UBERON:0007764 name: paramedian reticular nucleus def: "The paramedian reticular nucleus (in Terminologia Anatomica, or paramedian medullary reticular group in NeuroNames) sends its connections to the spinal cord in a mostly ipsilateral manner, although there is some decussation. It projects to the vermis in the anterior lobe, the pyramis and the uvula. The paramedian nucleus also projects to the contralateral PRN, the gigantocellular nucleus, and the nucleus ambiguous. The paramedian reticular formation is adjacent to the abducens (VI)nucleus in the pons and adjacent to the oculomotor nucleus(III) in the midbrain. The paramedian nucleus receives afferents mostly from the fastigial nucleus in the cerebellum and the cerebral cortex; however, the projections from the spinal cord are very sparse. The descending afferent connections come mostly from the frontal and parietal lobes; however the pontine reticular formation also sends projections to the paramedian reticular nucleus. There are also very sparse innervations from the superior colliculus. Lesions in the paramedian reticular nucleus have been shown to cause a stereotyped increase in the random patterns of motion in rats. The paramedian nuclei on either side of the brain stem have been shown to mediate the horizontal eye movements on their ipsilateral sides. It seems possible that that the random motion patterns of the above rats were caused by an inability to mediate their horizontal eye movements." [Wikipedia:Paramedian_reticular_nucleus] comment: todo - check synonym: "nucleus reticularis paramedianus" RELATED [Wikipedia:Paramedian_reticular_nucleus] synonym: "ventral paramedian reticular nucleus" EXACT [FMA:72583] xref: FMA:72583 ! ventral paramedian reticular nucleus xref: ABA:PMR ! Paramedian reticular nucleus is_a: UBERON:0007635 {source="FMA"} ! nucleus of medulla oblongata synonym: "paramedian nucleus reticularis" RELATED LATIN [Wikipedia:Paramedian_reticular_nucleus] [Term] id: UBERON:0001904 name: habenula def: "Habenula is a segment of the epithalamus that has as its parts the lateral and medial habenular nuclei and the habenular commissure. // The habenula relays impulses from limbic areas of the telencephalon to an unpaired midbrain nucleus, the interpeduncular nucleus." [Wikipedia:Habenula, ZFIN:curator] comment: TODO - add separate term for nucleus (e.g. BTO:0003685 habenular nucleus) subset: uberon_slim subset: vertebrate_core synonym: "habenulae" RELATED [] synonym: "habenular nuclei" RELATED [] synonym: "habenular nucleus" RELATED [] xref: FMA:62032 ! Habenula xref: GAID:619 ! habenula xref: MA:0000830 ! habenula xref: NIF_GrossAnatomy:birnlex_1611 ! Habenula xref: TAO:0000213 ! habenula xref: ZFA:0000213 ! habenula xref: BTO:0003684 ! habenula xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d7/Gray715.png/200px-Gray715.png xref: MESH:A08.186.211.577.200.360 ! habenula xref: EV:0100222 ! habenular nucleus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001899 ! epithalamus xref: SCTID:362389008 ! Entire habenula xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png property_value: external_definition "The habenula relays impulses from limbic areas of the telencephalon to an unpaired midbrain nucleus, the interpeduncular nucleus.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000213", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "habenular" xsd:string [Term] id: UBERON:0000445 name: habenular trigone def: "The habenular trigone is a small depressed triangular area situated in front of the superior colliculus and on the lateral aspect of the posterior part of the taenia thalami. It contains a group of nerve cells termed the ganglion habenulC&. Fibers enter it from the stalk of the pineal body, and others, forming what is termed the habenular commissure, pass across the middle line to the corresponding ganglion of the opposite side. Most of its fibers are, however, directed downward and form a bundle, the fasciculus retroflexus of Meynert, which passes medial to the red nucleus, and, after decussating with the corresponding fasciculus of the opposite side, ends in the interpeduncular ganglion." [Wikipedia:Habenular_trigone] comment: superclass in BTO is thalamic nucleus, not present in most ontologies synonym: "trigone of habenulae" RELATED [BTO:0002700] synonym: "trigonum habenulae" RELATED [BTO:0002700] xref: BTO:0002700 xref: FMA:74868 ! Habenular trigone is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001904 ! habenula relationship: part_of UBERON:0001894 ! diencephalon synonym: "trigonum habenulae" RELATED LATIN [Wikipedia:Habenular_trigone] [Term] id: UBERON:0001905 name: pineal body def: "The pineal body is an unpaired glandular organ subdivision shaped somewhat like a pine cone. It is attached on the midline near the posterior and habenular commissures of the epithalamus." [Wikipedia:Pineal_gland] subset: uberon_slim subset: vertebrate_core synonym: "glandula pinealis" EXACT LATIN [FMA:TA] synonym: "pineal gland" EXACT [FMA:62033] synonym: "corpus pineale" EXACT [] synonym: "epiphysis" RELATED INCONSISTENT [ZFA:0000019] synonym: "epiphysis cerebri" RELATED [Wikipedia:Epiphysis_cerebri] synonym: "pineal organ" EXACT [ZFA:0000019] xref: BTO:0001067 xref: EFO:0000865 ! pineal gland xref: EHDAA:7523 ! pineal gland xref: FMA:62033 ! Pineal body xref: GAID:453 ! pineal gland xref: VHOG:0000051 ! pineal gland xref: MA:0000175 ! pineal gland xref: MAT:0000448 ! pineal gland xref: ncithesaurus:Pineal_Gland xref: NIF_GrossAnatomy:birnlex_1184 ! Pineal body xref: NIF_GrossAnatomy:nlx_anat_1010009 ! Pineal gland xref: OpenCyc:Mx4rv2FMGpwpEbGdrcN5Y29ycA xref: XAO:0000160 ! pineal gland xref: ZFA:0000019 ! epiphysis xref: galen:PinealGland ! pineal gland xref: OpenCyc:Mx4rv2FMGpwpEbGdrcN5Y29ycA ! pineal gland xref: EHDAA2:0001466 ! pineal gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Illu_pituitary_pineal_glands.jpg/200px-Illu_pituitary_pineal_glands.jpg xref: EMAPA:18778 ! pineal gland xref: MESH:A06.407.635 ! pineal gland xref: EV:0100221 ! pineal body xref: EV:0100131 ! pineal gland xref: ABA:PIN ! Pineal body xref: BM:P ! corpus pineale is_a: UBERON:0010134 {source="MA"} ! secretory circumventricular organ relationship: part_of UBERON:0001899 {source="multiple"} ! epithalamus relationship: spatially_disjoint_from UBERON:0001941 {source="ABA"} ! lateral habenular nucleus relationship: spatially_disjoint_from UBERON:0001942 {source="ABA"} ! medial habenular nucleus synonym: "glandula pinealis" EXACT LATIN [FMA:TA, FMA:62033] xref: AAO:0010549 ! pineal body xref: SCTID:181126002 ! Entire pineal gland subset: organ_slim xref: TAO:0000019 ! epiphysis xref: http://upload.wikimedia.org/wikipedia/commons/6/6b/Illu_pituitary_pineal_glands.jpg property_value: external_definition "Anatomical structure which is a medial outgrowth of the thalamus on the dorsal surface of the brain. This structure is light sensitive and secretes melatonin when exposed to prolonged darkness.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010549", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "A circumscribed swelling, includes the pineal primordium that appears late in the segmentation period in the dorsal midline of the diencephalon. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000019", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of pineal complex (TAO:0001359)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000019", date_retrieved="2012-08-14"} synonym: "frontal organ" RELATED [VHOG:0000051] synonym: "pineal" RELATED [VHOG:0000051] synonym: "stirnorgan" RELATED [VHOG:0000051] property_value: homology_notes "The pineal gland has evolved from a part of the epiphyseal complex of anamniotes, which includes a median light-receptive pineal eye, parietal eye, or both.[well established][VHOG]" xsd:string {external_class="VHOG:0000051", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.516", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "epiphyseal" xsd:string property_value: has_relational_adjective "epiphysial" xsd:string xref: UMLS:C0031939 [Term] id: UBERON:0011768 name: pineal gland stalk comment: Editors note: compare with habenula synonym: "epiphyseal stalk" EXACT [ZFA:0001292] synonym: "habenula" RELATED [] is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0001905 {source="VHOG", source="EMAPA"} ! pineal body xref: VHOG:0001360 ! pineal gland stalk xref: ZFA:0001292 ! epiphyseal stalk xref: TAO:0001292 ! epiphyseal stalk xref: EMAPA:19036 ! stalk property_value: external_definition "The stalk emanates from the diencephalic roof at a left-of-medial position.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001292", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of pineal complex (TAO:0001359)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001292", date_retrieved="2012-08-14"} synonym: "pineal stalk" EXACT [TAO:0001292] property_value: homology_notes "The epithalamus contains the epiphysis (pineal gland and related structures), which is located at the end of a stalk, the epiphyseal stalk.[well established][VHOG]" xsd:string {external_class="VHOG:0001360", ontology="VHOG", source="ISBN:978-0471210054 Butler AB\, Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.66", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001906 name: subthalamic nucleus def: "The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function[GO]." [Wikipedia:Subthalamic_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "body of forel" EXACT [] synonym: "body of luys" EXACT [] synonym: "nucleus of corpus luysii" EXACT [] synonym: "nucleus of luys" EXACT [] synonym: "subthalamic nucleus (of luys)" EXACT [] synonym: "Luys' body" RELATED [BTO:0002252] synonym: "nucleus subthalamicus" RELATED [BTO:0002252] xref: FMA:62035 ! Subthalamic nucleus xref: GAID:655 ! subthalamic nucleu xref: MA:0000877 ! subthalamic nucleus xref: ncithesaurus:Subthalamic_Nucleus ! Subthalamic Nucleus xref: BTO:0002252 ! subthalamic nucleus xref: EFO:0001392 ! subthalamic nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/33/Basal-ganglia-coronal-sections-large.png/200px-Basal-ganglia-coronal-sections-large.png xref: NIF_GrossAnatomy:nlx_anat_1010002 ! Subthalamic nucleus xref: MESH:A08.186.211.730.385.800.800 ! subthalamic nucleu xref: EV:0100224 ! subthalamic nucleus xref: ABA:STN ! Subthalamic nucleus xref: BM:Die-Sb ! subthalamic nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001900 ! subthalamus relationship: spatially_disjoint_from UBERON:0002430 {source="ABA"} ! lateral hypothalamic area relationship: spatially_disjoint_from UBERON:0001931 {source="ABA"} ! lateral preoptic nucleus relationship: spatially_disjoint_from UBERON:0001933 {source="ABA"} ! retrochiasmatic area relationship: spatially_disjoint_from UBERON:0001907 {source="ABA"} ! zona incerta synonym: "nucleus subthalamicus" RELATED LATIN [Wikipedia:Subthalamic_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/3/33/Basal-ganglia-coronal-sections-large.png xref: UMLS:C0152355 [Term] id: UBERON:0001907 name: zona incerta def: "The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord. Its function is unknown though several have been proposed related to “limbic–motor integration” such as controlling visceral activity and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms. Its dysfunction may play a role in central pain syndrome. It is also been identified as a promising deep brain stimulation therapy target for treating Parkinsons Disease. Its existence was first described by Auguste Forel in 1877 as a “region of which nothing certain can be said”. A hundred and thirty years later in 2007, Nadia Urbain and Martin Deschênes of Université Laval noted that the “zona incerta is among the least studied regions of the brain; its name does not even appear in the index of many textbooks. ” [WP,unvetted]." [Wikipedia:Zona_incerta] subset: uberon_slim xref: FMA:62038 ! Zona incerta xref: MA:0000878 ! zona incerta xref: BTO:0003146 ! zona incerta xref: ABA:ZI ! Zona incerta xref: BM:Die-VTh-ZI ! zona incerta is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001900 ! subthalamus relationship: spatially_disjoint_from UBERON:0002430 {source="ABA"} ! lateral hypothalamic area relationship: spatially_disjoint_from UBERON:0001931 {source="ABA"} ! lateral preoptic nucleus relationship: spatially_disjoint_from UBERON:0001933 {source="ABA"} ! retrochiasmatic area relationship: spatially_disjoint_from UBERON:0001906 {source="ABA"} ! subthalamic nucleus xref: SCTID:369186007 ! Entire zona incerta [Term] id: UBERON:0001910 name: medial forebrain bundle def: "The Medial forebrain bundle (MFB), is a complex bundle of axons coming from the basal olfactory regions, the periamygdaloid region, and the septal nuclei, and passing to the lateral hypothalamus, with some carrying on into the tegmentum. It contains both ascending and descending fibers. It also represents a part of the mesolimbic pathway, carrying information between the ventral tegmentum and the nucleus accumbens. It is commonly accepted that the MFB is a part of the reward system, involved in the integration of reward and pleasure. Electrical stimulation of the medial forebrain bundle is believed to cause sensations of pleasure. This hypothesis is based upon intracranial self-stimulation (ICSS) studies. Animals will work for MFB ICSS, and humans report that MFB ICSS is intensely pleasurable. This is most likely because the medial forebrain bundle carries information from the ventral tegmental area (VTA) to the nucleus accumbens (nAcc or Acb). The nAcc is a recognized reward center, and activation of the pathway from the VTA to the nAcc is believed to be rewarding, which is why it is sometimes referred to as the hedonic highway. [WP,unvetted]." [Wikipedia:Medial_forebrain_bundle] comment: AO notes: a pathway in NCIT subset: uberon_slim subset: vertebrate_core synonym: "medial forebrain fasciculus" EXACT [] synonym: "telencephalic medial fasciculus" EXACT [] xref: FMA:62064 ! Medial forebrain bundle xref: GAID:736 ! medial forebrain bundle xref: NIF_GrossAnatomy:birnlex_908 ! Medial forebrain bundle xref: TAO:0005111 ! medial forebrain bundle xref: ZFA:0005111 ! medial forebrain bundle xref: ncithesaurus:Medial_Forebrain_Bundle ! Medial Forebrain Bundle xref: MESH:A08.612.492 ! medial forebrain bundle is_a: UBERON:0005838 ! fasciculus of brain relationship: part_of UBERON:0000955 ! brain synonym: "fasciculus medialis telencephali" RELATED LATIN [Wikipedia:Medial_forebrain_bundle] xref: UMLS:C0025055 [Term] id: UBERON:0013614 name: fasciculus aberans def: "The fasciulus aberrans is a distinct bundle of fibers at the dorsal aspect of the anterior commisure. These fibers travel in the internal capsule between the putamen and caudate nuclei, and cross the midline to connect the dorsal neocortex of the two hemispheres. When the fasciculus aberrans is absent, the fibers connecting the neocortex of the two hemispheres takes a diffderent route through the external capsule[Johnson et al., (1982a, 1982b, 1994)]" [MorphoBank:177] is_a: UBERON:0002473 ! intercerebral commissure is_a: UBERON:0005838 {source="cjm"} ! fasciculus of brain [Term] id: UBERON:0005333 ! mammary bud name: mammary bud alt_id: UBERON:0004181 ! mammary gland bud def: "Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord[GO]. produced along the length of the embryonic mammary ridge these buds represent the future locations of the mammary glands. Invagination of ectoderm at each bud leads to the development of epithelial diverticula, later maturing as lactiferous ducts[TFD]." [http://medical-dictionary.thefreedictionary.com/mammary+bud, GO:0060648] synonym: "mammary gland bud" EXACT [GO:0060648] synonym: "milk bud" RELATED [] is_a: UBERON:0005153 ! epithelial bud relationship: part_of UBERON:0000076 {source="PMID:20484386"} ! external ectoderm relationship: develops_from UBERON:0005311 ! mammary placode [Term] id: UBERON:0005311 ! mammary placode name: mammary placode def: "The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper[GO]." [GO:0060596] comment: TODO develops_from is_a: UBERON:0011814 {source="NBK53175"} ! non-neurogenic ectodermal placode relationship: develops_from UBERON:0008425 {source="Stedmans"} ! mammary ridge [Term] id: UBERON:0004182 name: mammary gland cord def: "Mammary gland cords form when the mammary gland bud invades the mammary fat" [GO:0060652] comment: TODO - mammary placode intersection_of: UBERON:0005154 ! epithelial cord intersection_of: part_of UBERON:0001765 ! lactiferous duct [Term] id: UBERON:0001765 name: mammary duct def: "Epithelial tube that transports milk[GO]." [GO:0060603, Wikipedia:Lactiferous_duct] comment: This structure regresses in most males subset: uberon_slim synonym: "mammary gland duct" EXACT [] synonym: "ductus lactiferi" RELATED [BTO:0002845] synonym: "galactophorous tubule" RELATED [BTO:0002845] synonym: "lactiferous tubule" RELATED [BTO:0002845] synonym: "lactiferous duct" EXACT [FMA:58006] synonym: "lactiferous gland duct" EXACT [OBOL:automatic] xref: FMA:58006 ! Lactiferous duct xref: MA:0000791 ! mammary gland duct xref: ncithesaurus:Lactiferous_Duct ! Lactiferous Duct xref: BTO:0002845 ! mammary duct is_a: UBERON:0003914 ! epithelial tube intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001911 ! lactiferous gland relationship: channel_for UBERON:0001913 ! milk relationship: channels_into UBERON:0002030 ! nipple xref: SCTID:361719004 ! Entire lactiferous duct synonym: "ductus lactiferi" RELATED LATIN [Wikipedia:Lactiferous_duct] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Illu_breast_anatomy.jpg xref: UMLS:C0222613 [Term] id: UBERON:0001911 name: mammary gland def: "The specialized accessory gland of the skin of female mammals that secretes milk. In the human female, it is a compound tubuloalveolar gland composed of 15 to 25 lobes arranged radially about the nipple and separated by connective and adipose tissue, each lobe having its own excretory (lactiferous) duct opening on the nipple. The lobes are subdivided into lobules, with the alveolar ducts and alveoli being the secretory portion of the gland[BTO]. The mouse forms five to six pairs of mammary glands that extend from the neck to the groin." [Wikipedia:Mammary_gland, BTO:0000817] comment: Note that this class corresponds to the generic mammary gland. The human mammary gland is in the thoracic/breast region and is therefore covered by the subclass "thoracic mammary gland" // Males typically only have rudimentary mammary glands, The male Dayak fruit bat has lactating mammary glands. Male lactation occurs infrequently in some species. We make a part_of association to female organism for now as this is the canonical case // AO notes: in MP, this is implicitly part of female reproductive system, but not female genitalia // A mouse mammary gland contains a single duct or sinus, forming 5-10 secondary ducts subset: uberon_slim synonym: "lobe of breast" EXACT [] synonym: "lobe of mammary gland" EXACT [] synonym: "lactiferous gland" EXACT [FMA:62088] synonym: "Brustdruese" RELATED [BTO:0000817] synonym: "glandula mammaria" EXACT PLURAL [FMA:TA, FMA:57983] synonym: "mamma" RELATED [BTO:0000817] synonym: "mammae" RELATED PLURAL [] synonym: "dug" RELATED [Wikipedia:Mammary_gland] xref: BTO:0000817 ! mammary gland xref: EFO:0000854 ! mammary gland xref: VHOG:0000398 ! mammary gland xref: MA:0000145 ! mammary gland xref: MAT:0000073 ! mammary gland xref: MIAA:0000073 ! mammary gland xref: ncithesaurus:Mammary_Gland xref: OpenCyc:Mx4rvVjVq5wpEbGdrcN5Y29ycA ! mammary gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Illu_breast_anatomy.jpg/200px-Illu_breast_anatomy.jpg xref: EMAPA:17759 ! mammary gland xref: MESH:A10.336.482 ! mammae xref: EV:0100125 ! mammary gland is_a: UBERON:0002365 {source="MA"} ! exocrine gland intersection_of: UBERON:0002530 ! gland intersection_of: secretes UBERON:0001913 ! milk relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: develops_from UBERON:0005333 ! mammary bud relationship: part_of UBERON:0003100 {notes="see comments"} ! female organism relationship: part_of UBERON:0000474 {source="VHOG", notes="see comments"} ! female reproductive system xref: SCTID:361720005 ! Entire lobe of breast subset: organ_slim synonym: "glandula mammaria" RELATED LATIN [Wikipedia:Mammary_gland] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Illu_breast_anatomy.jpg property_value: external_definition "Any of the milk-producing apocrine glands typically occurring in pairs in female mammals and consisting of lobes containing clusters of alveoli with a system of ducts to convey the milk to an external nipple or teat. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000398", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/mammary+gland", source="http://bgee.unil.ch/"} property_value: homology_notes "The detailed similarities of mammary glands in living monotremes, marsupials, and eutherians argue for a monophyletic origin of these glands, perhaps by the combination of parts of preexisting sebaceous and sweat glands.[well established][VHOG]" xsd:string {external_class="VHOG:0000398", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.224", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "mammary" xsd:string xref: UMLS:C0929301 [Term] id: UBERON:0005199 name: cervical mammary gland xref: MA:0000789 ! cervical mammary gland intersection_of: UBERON:0001911 ! mammary gland intersection_of: part_of UBERON:0005434 ! cervical region def: "A mammary gland that is part of a cervical region." [OBOL:automatic] [Term] id: UBERON:0005200 name: thoracic mammary gland def: "A lactiferous gland that is located in the thoracic region/breast." [UBERON:cjm, Wikipedia:Mammary_gland#Other_mammals] comment: Most primates have one pair of mammary glands, which are thoracic. synonym: "anterior mammary gland" RELATED [Wikipedia:Mammary_gland#Other_mammals] synonym: "breast mammary gland" EXACT [] synonym: "lactiferous gland" BROAD SENSU [FMA:62088] synonym: "mammary gland" BROAD SENSU [FMA:62088] relationship: part_of UBERON:0000310 {source="BTO"} ! breast xref: MA:0000797 ! thoracic mammary gland xref: EHDAA:6524 ! mammary gland xref: FMA:62088 ! Lactiferous gland xref: EHDAA2:0001056 ! mammary gland xref: SCTID:31448001 ! Caudal thoracic mammary gland intersection_of: UBERON:0001911 ! mammary gland intersection_of: part_of UBERON:0000915 ! throax relationship: part_of UBERON:0000310 {source="BTO"} ! breast [Term] id: UBERON:0003488 name: abdominal mammary gland def: "A lactiferous gland that is part of the abdominal region [Automatically generated definition]." [OBOL:automatic] comment: Taxon notes: Female mice normally have five pairs of nipples and mammary glands, three in the thoracic and two in the abdominal region. (There is an additional abdominal pair in female rats.) http://www.informatics.jax.org/greenbook/chapters/chapter13.shtml synonym: "abdomen lactiferous gland" EXACT [OBOL:automatic] synonym: "abdomen lobe of breast" EXACT [OBOL:automatic] synonym: "abdomen lobe of mammary gland" EXACT [OBOL:automatic] synonym: "abdomen mammary gland" EXACT [OBOL:automatic] synonym: "lactiferous gland of abdomen" EXACT [OBOL:automatic] synonym: "lobe of breast of abdomen" EXACT [OBOL:automatic] synonym: "lobe of mammary gland of abdomen" EXACT [OBOL:automatic] synonym: "mammary gland of abdomen" EXACT [OBOL:automatic] xref: MA:0000787 ! abdominal mammary gland xref: SCTID:68037003 ! Cranial abdominal mammary gland xref: SCTID:113191002 ! Caudal abdominal mammary gland intersection_of: UBERON:0001911 ! lactiferous gland intersection_of: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0008424 name: inguinal mammary gland intersection_of: UBERON:0001911 ! mammary gland intersection_of: part_of UBERON:0008337 ! inguinal part of abdomen xref: MA:0000790 ! inguinal mammary gland xref: SCTID:66519003 ! Inguinal mammary gland def: "A mammary gland that is part of a inguinal part of abdomen." [OBOL:automatic] [Term] id: UBERON:0013216 name: udder def: "A large pendulous organ consisting of two or more mammary glands enclosed in a common envelope and each provided with a single nipple." [Wikipedia:Udder] xref: SCTID:27528008 ! Udder is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0003100 ! female organism relationship: has_part UBERON:0001911 ! mammary gland property_value: external_definition "An udder is an organ formed of the mammary glands of female quadruped mammals, especially ruminants such as cattle, goats, sheep and deer. The udder is a single mass hanging beneath the animal, consisting of pairs of mammary glands. In cattle there are normally two pairs, in sheep, goats and deer there is one pair, and in some animals such as pigs there are many pairs. Udder care and hygiene in cows is important in milking, aiding uninterrupted and untainted milk production, and preventing mastitis. Products exist to soothe the chapped skin of the udder. This helps prevent bacterial infection, and reduces irritation during milking by the cups, and so the cow is less likely to kick the cups off[Wikipedia:Udder]." xsd:string {source="Wikipedia:Udder"} [Term] id: UBERON:0011827 ! areolar gland name: areolar gland def: "Lobular organ the parenchyma of which consists of acini connected to the surface of the areola or to a lactiferous duct by the duct of areolar gland. Examples: There are variable numbers of areolar glands." [FMA:58090, Wikipedia:Areolar_glands] is_a: UBERON:0001821 ! sebaceous gland relationship: part_of UBERON:0002030 ! nipple synonym: "accessory gland of breast" EXACT [FMA:58090] synonym: "accessory gland of Montgomery" EXACT [FMA:58090] synonym: "gland of Montgomery" EXACT [] synonym: "Montgomery's gland" EXACT [] xref: FMA:58090 ! areolar gland xref: SCTID:279034002 ! Entire gland of Montgomery xref: ncithesaurus:Montgomery_s_Tubercle ! montgomery tubercle xref: UMLS:C0929386 [Term] id: UBERON:0011828 name: areolar tubercle synonym: "tubercle of Montgomery" EXACT [] synonym: "Montgomery's tubercle" EXACT [] synonym: "Montgomery tubercle" EXACT [] is_a: UBERON:0005813 {source="FMA"} ! tubercle relationship: part_of UBERON:0002030 ! nipple relationship: overlaps UBERON:0011827 ! areolar gland xref: FMA:58091 ! areolar tubercle [Term] id: UBERON:0011830 name: duct of lesser vestibular gland synonym: "lesser vestibular gland duct" EXACT [FMA:20094] intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0000461 ! minor vestibular gland xref: FMA:20094 ! duct of lesser vestibular gland def: "A duct that is part of a minor vestibular gland." [OBOL:automatic] [Term] id: UBERON:0011831 name: duct of vestibular gland synonym: "vestibular gland duct" EXACT [FMA:20097] intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0011826 ! vestibular gland xref: FMA:20097 ! duct of vestibular gland def: "A duct that is part of a vestibular gland." [OBOL:automatic] [Term] id: UBERON:0011844 name: duct of areolar gland synonym: "areolar gland duct" EXACT [FMA:67744] is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0011827 ! areolar gland xref: FMA:67744 ! duct of areolar gland [Term] id: UBERON:0011845 name: duct of sebaceous gland synonym: "sebaceous gland duct" EXACT [FMA:70947] intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001821 ! sebaceous gland xref: FMA:70947 ! duct of sebaceous gland def: "A duct that is part of a sebaceous gland." [OBOL:automatic] [Term] id: UBERON:0008425 ! mammary ridge name: mammary ridge def: "A bandlike thickening of ectoderm in the embryo extending from just below the axilla to the inguinal region and giving rise to the mammary glands[Stedmans]. One of two parallel lines, formed by thickenings of the epidermis (the mammary ridge) along the ventral surface of mammals of both sexes. They extend from the upper limbs (arms) to the lower limbs (legs) and are developed in the embryo. They give rise to the mammary glands and nipples but are otherwise usually not visible in the adult. The first manifestation of the mammary gland in many mammals is an elevated ridge or milk line, which then fragments into individual buds in specific regions lateral of the dorsal midline. These buds are either located in the thoracic region in primates, in the inguinal area in ungulates or along the entire length of the trunk in rodents and pigs. In humans, milk lines appear in the seventh week of embryonic development. After initial development of the milk lines they go into remission. Nipples develop on the milk lines of mammals. Most humans have two nipples, but in some cases more than two will develop. In most cases, these 'third nipples'—and sometimes fourth nipple—grow along the milk line[WP]." [Wikipedia:Milk_line, http://dictionary.reference.com/browse/mammary%20ridge] comment: split ridge and milk line? synonym: "mammary fold" EXACT [http://dictionary.reference.com/browse/mammary+ridge] synonym: "milk line" RELATED [Wikipedia:Milk_line] xref: EMAPA:18541 ! ridge is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000924 ! ectoderm relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0001912 name: lobule of lactiferous gland def: "Organ component of the mammary gland which consists of an aggregate of mammary alveoli that communicate with a lobular lactiferous duct.[FMA]" [FMA:62090] comment: TODO - ensure correct terminology for lobes/lobules. FMA uses lobule for core term, but also has 'set of mammary gland lobes'. ISBN10:0123813611 states no separate lobes in mouse subset: uberon_slim synonym: "acinus of mammary gland" EXACT [] synonym: "lactiferous acinus" EXACT [] synonym: "lactiferous gland lobule" EXACT [] synonym: "lactiferous lobule" EXACT [] synonym: "lobule of mammary gland" EXACT [] synonym: "mammary acinus" EXACT [] synonym: "mammary gland lobule" EXACT [] synonym: "lobe of breast" RELATED [BTO:0004718] synonym: "lobe of mammary gland" RELATED [BTO:0004718] synonym: "lobi glandulae mammariae" RELATED [BTO:0004718] synonym: "lobus glandulae mammariae" RELATED [BTO:0004718] synonym: "breast lobe" RELATED [BTO:0004718] xref: FMA:62090 ! Lobule of lactiferous gland xref: MA:0000793 ! mammary gland lobule xref: BTO:0004718 ! breast lobe is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001911 ! lactiferous gland [Term] id: UBERON:0001915 name: endothelium of capillary def: "An endothelium that is part of a capillary [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "capillary endothelium" EXACT [] synonym: "blood capillary endothelium" EXACT [OBOL:automatic] synonym: "capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel" EXACT [OBOL:automatic] xref: FMA:62114 ! Endothelium of capillary xref: MA:0000711 ! capillary endothelium xref: ncithesaurus:Capillary_Endothelium ! Capillary Endothelium xref: BTO:0004954 ! capillary endothelium is_a: UBERON:0001986 ! endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001982 ! capillary relationship: part_of UBERON:0001982 ! capillary xref: UMLS:C0006904 [Term] id: UBERON:0001916 name: endothelium of arteriole def: "An endothelium that is part of an arteriole [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "arteriole endothelium" EXACT [] xref: FMA:62115 ! Endothelium of arteriole xref: MA:0000705 ! arteriole endothelium xref: ncithesaurus:Arteriole_Endothelium ! Arteriole Endothelium is_a: UBERON:0001986 ! endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001980 ! arteriole relationship: part_of UBERON:0001980 ! arteriole xref: UMLS:C1179024 [Term] id: UBERON:0001917 name: endothelium of artery def: "An endothelium that is part of an artery [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "arterial endothelium" EXACT [] synonym: "artery endothelium" EXACT [] xref: FMA:62116 ! Endothelium of artery xref: VHOG:0001215 ! arterial endothelium xref: MA:0000707 ! artery endothelium xref: XAO:0000357 ! arterial endothelium xref: ncithesaurus:Artery_Endothelium ! Artery Endothelium xref: BTO:0004757 ! arterial endothelium is_a: UBERON:0003915 ! endothelial tube intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001637 ! artery xref: AAO:0011013 ! arterial endothelium property_value: external_definition "The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011013", date_retrieved="2012-06-20", source="XAO:curator"} property_value: homology_notes "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {external_class="VHOG:0001215", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1179025 [Term] id: UBERON:0004700 name: arterial system endothelium def: "An endothelium that is part of an arterial system [Automatically generated definition]." [OBOL:automatic] xref: MA:0000703 ! arterial system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004572 ! part_of arterial system xref: ncithesaurus:Arterial_System_Endothelium ! Arterial System Endothelium xref: UMLS:C1706849 [Term] id: UBERON:0001918 name: endothelium of venule def: "An endothelium that is part of a venule [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "venule endothelium" EXACT [] xref: FMA:62117 ! Endothelium of venule xref: MA:0000716 ! venule endothelium xref: ncithesaurus:Venule_Endothelium ! Venule Endothelium is_a: UBERON:0001986 ! endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001979 ! venule relationship: part_of UBERON:0001979 ! venule xref: UMLS:C1179026 [Term] id: UBERON:0001919 name: endothelium of vein def: "An endothelium that is part of a vein [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "vein endothelium" EXACT [] synonym: "venous endothelium" EXACT [] xref: FMA:62118 ! Endothelium of vein xref: VHOG:0001216 ! venous endothelium xref: MA:0000712 ! vein endothelium xref: ncithesaurus:Vein_Endothelium ! Vein Endothelium xref: XAO:0000358 ! venous endothelium xref: BTO:0004756 ! venous endothelium is_a: UBERON:0001986 ! endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001638 ! vein xref: AAO:0011110 ! venous endothelium synonym: "veinous endothelium" RELATED [VHOG:0001216] property_value: homology_notes "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {external_class="VHOG:0001216", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1179027 [Term] id: UBERON:0001921 name: reuniens nucleus comment: This class was created automatically from a combination of ontologies synonym: "medioventral nucleus" EXACT [] synonym: "nucleus reuniens" EXACT [] synonym: "reuniens thalamic nucleus" EXACT [] xref: FMA:62153 ! Reuniens nucleus xref: MA:0000865 ! nucleus reuniens xref: NIF_GrossAnatomy:birnlex_770 ! Reuniens nucleus xref: BTO:0002459 ! nucleus reuniens is_a: UBERON:0002308 ! nucleus of brain xref: SCTID:369164006 ! Entire reuniens nucleus of thalamus [Term] id: UBERON:0001922 name: parafascicular nucleus comment: This class was created automatically from a combination of ontologies synonym: "parafascicular nucleus of thalamus" EXACT [] synonym: "parafascicular thalamic nucleus" EXACT [] synonym: "nuclei parafasciculares thalami" EXACT [NIF_GrossAnatomy:birnlex_952] synonym: "nucleus parafascicularis" EXACT [NIF_GrossAnatomy:birnlex_952] synonym: "nucleus parafascicularis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_952] synonym: "nucleus parafascicularis thalami" EXACT [NIF_GrossAnatomy:birnlex_952] synonym: "parafascicular nucleus (vogt)" EXACT [NIF_GrossAnatomy:birnlex_952] synonym: "parafascicular nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_952] xref: FMA:62166 ! Parafascicular nucleus xref: MA:0000874 ! parafascicular nucleus xref: NIF_GrossAnatomy:birnlex_952 ! Parafascicular nucleus xref: EV:0100202 ! parafascicular thalamic nucleus xref: ABA:PF ! Parafascicular nucleus xref: BM:Die-Th-Pf ! parafascicular nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002733 {source="FMA"} ! intralaminar nuclear group relationship: spatially_disjoint_from UBERON:0003036 {source="ABA"} ! central lateral nucleus relationship: spatially_disjoint_from UBERON:0001923 {source="ABA"} ! central medial nucleus relationship: spatially_disjoint_from UBERON:0001924 {source="ABA"} ! paracentral nucleus relationship: spatially_disjoint_from UBERON:0002955 {source="ABA"} ! rhomboidal nucleus xref: ncithesaurus:Parafascicular_Nucleus_of_the_Thalamus ! Parafascicular Nucleus of the Thalamus xref: SCTID:279150008 ! Entire parafascicular nucleus of thalamus xref: UMLS:C0228352 [Term] id: UBERON:0001923 name: central medial nucleus def: "a small cell group in the interthalamic adhesion of the thalamus that occupy the midline region of the internal medullary lamina, between the left and right paracentral nuclei." [MP:0008929] comment: This class was created automatically from a combination of ontologies synonym: "central medial nucleus of thalamus" EXACT [] synonym: "central medial thalamic nucleus" EXACT [] synonym: "central medial nucleus thalamus (rioch 1928)" EXACT [NIF_GrossAnatomy:birnlex_971] synonym: "nucleus centralis medialis" EXACT [NIF_GrossAnatomy:birnlex_971] synonym: "nucleus centralis medialis thalami" EXACT [NIF_GrossAnatomy:birnlex_971] xref: FMA:62171 ! Central medial nucleus xref: MA:0000872 ! central medial nucleus xref: NIF_GrossAnatomy:birnlex_971 ! Central medial nucleus xref: BTO:0003753 ! central medial thalamic nucleus xref: ABA:CM ! Central medial nucleus of the thalamus xref: BM:Die-CeM ! central medial nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0003036 {source="ABA"} ! central lateral nucleus relationship: spatially_disjoint_from UBERON:0001924 {source="ABA"} ! paracentral nucleus relationship: spatially_disjoint_from UBERON:0001922 {source="ABA"} ! parafascicular nucleus relationship: spatially_disjoint_from UBERON:0002955 {source="ABA"} ! rhomboidal nucleus xref: SCTID:279161000 ! Entire central medial nucleus of thalamus [Term] id: UBERON:0001924 name: paracentral nucleus def: "one of the intralaminar nuclei of the thalamus, located medial to the central lateral nucleus." [MP:0008928] comment: todo - relationships synonym: "paracentral nucleus of thalamus" EXACT [] synonym: "paracentral thalamic nucleus" EXACT [] synonym: "nucleus centralis lateralis superior (kusama)" EXACT [NIF_GrossAnatomy:birnlex_981] synonym: "nucleus paracentral" EXACT [NIF_GrossAnatomy:birnlex_981] synonym: "nucleus paracentral thalami" EXACT [NIF_GrossAnatomy:birnlex_981] synonym: "paracentral nucleus thalamus (gurdjian 1927)" EXACT [NIF_GrossAnatomy:birnlex_981] xref: FMA:62172 ! Paracentral nucleus xref: MA:0000873 ! paracentral nucleus xref: NIF_GrossAnatomy:birnlex_981 ! Paracentral nucleus xref: EV:0100204 ! paracentral thalamic nucleus xref: ABA:PCN ! Paracentral nucleus xref: BM:Die-Th-Pc ! paracentral nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002733 {source="FMA"} ! intralaminar nuclear group relationship: spatially_disjoint_from UBERON:0003036 {source="ABA"} ! central lateral nucleus relationship: spatially_disjoint_from UBERON:0001923 {source="ABA"} ! central medial nucleus relationship: spatially_disjoint_from UBERON:0001922 {source="ABA"} ! parafascicular nucleus relationship: spatially_disjoint_from UBERON:0002955 {source="ABA"} ! rhomboidal nucleus synonym: "nucleus paracentralis thalami" EXACT LATIN [FMA:TA, FMA:62172] xref: SCTID:279152000 ! Entire paracentral nucleus of thalamus [Term] id: UBERON:0001925 name: ventral lateral nucleus def: "The ventral lateral nucleus (VL) is a nucleus of the thalamus. [WP,unvetted]." [Wikipedia:Ventral_lateral_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "lateral ventral nucleus of thalamus" EXACT [] synonym: "ventral lateral complex of thalamus" EXACT [] synonym: "ventral lateral nucleus of thalamus" EXACT [] synonym: "ventral lateral thalamic nuclei" EXACT [] synonym: "ventrolateral thalamic nucleus" EXACT [] synonym: "ventrolateral nucleus of the thalamus" EXACT [] synonym: "nucleus ventralis intermedius" EXACT [NIF_GrossAnatomy:birnlex_1237] synonym: "nucleus ventralis lateralis" EXACT [NIF_GrossAnatomy:birnlex_1237] synonym: "nucleus ventralis lateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_1237] synonym: "nucleus ventralis thalami lateralis" EXACT [NIF_GrossAnatomy:birnlex_1237] synonym: "nucleus ventrolateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_1237] synonym: "ventral lateral thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_1237] synonym: "nuclei ventrales laterales thalami" RELATED [BTO:0002463] synonym: "ventral lateral nuclei of thalamus" RELATED [BTO:0002463] xref: FMA:62186 ! Ventral lateral nucleus xref: NIF_GrossAnatomy:birnlex_1237 ! Ventral lateral nucleus xref: TAO:0000306 ! ventrolateral thalamic nucleus xref: ZFA:0000306 ! ventrolateral thalamic nucleus xref: BTO:0002463 ! ventral lateral complex of thalamus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: BM:Die-Th-VL ! ventral lateral nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001900 ! subthalamus xref: SCTID:279146001 ! Nucleus ventralis intermedius xref: ncithesaurus:Ventrolateral_Nucleus_of_the_Thalamus ! Ventrolateral Nucleus of the Thalamus xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png xref: UMLS:C0228339 [Term] id: UBERON:0012174 name: obsolete geniculate nucleus comment: inappropriate grouping synonym: "geniculate body" EXACT [] xref: SCTID:362376002 ! Entire geniculate body xref: EFO:0002463 ! geniculate nucleus is_obsolete: true consider: UBERON:0001926 ! lateral geniculate body consider: UBERON:0001927 ! medial geniculate body [Term] id: UBERON:0001926 name: lateral geniculate body def: "The lateral geniculate nucleus is the primary processor of visual information received from the retina[GO]." [Wikipedia:Lateral_geniculate_body] comment: Note that BTO has distinct classes for body and nucleus, but other sources treat as identical subset: uberon_slim synonym: "external geniculate body" RELATED [Wikipedia:Lateral_geniculate_nucleus] synonym: "lateral geniculate complex" EXACT [] synonym: "lateral geniculate nucleus" EXACT [] synonym: "corpus geniculatum externum" RELATED [BTO:0004367] synonym: "corpus geniculatum laterales" EXACT [NIF_GrossAnatomy:birnlex_1662] synonym: "nucleus geniculatus lateralis" EXACT [NIF_GrossAnatomy:birnlex_1662] xref: FMA:62209 ! Lateral geniculate body xref: MA:0000869 ! lateral geniculate nucleus xref: NIF_GrossAnatomy:birnlex_1662 ! Lateral geniculate body xref: EFO:0001988 ! lateral geniculate nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Gray719.png/200px-Gray719.png xref: BTO:0004366 ! lateral geniculate nucleus xref: BTO:0004367 ! lateral geniculate body xref: EV:0100219 ! lateral geniculate nucleus is_a: UBERON:0007692 {source="FMA"} ! nucleus of thalamus relationship: part_of UBERON:0002704 {source="FMA"} ! metathalamus xref: SCTID:362377006 ! Entire lateral geniculate body xref: ncithesaurus:External_Geniculate_Body ! External Geniculate Body xref: UMLS:C0086526 [Term] id: UBERON:0001927 name: medial geniculate body def: "The Medial Geniculate Nucleus (MGN) or Medial Geniculate Body (MGB) is part of the auditory thalamus and represents the thalamic relay between the inferior colliculus (IC) and the auditory cortex (AC). It is made up of a number of sub-nuclei that are distinguished by their neuronal morphology and density, by their afferent and efferent connections, and by the coding properties of their neurons. It is thought that the MGB influences the direction and maintenance of attention. [WP,unvetted]." [Wikipedia:Medial_geniculate_body] subset: uberon_slim synonym: "medial geniculate complex" EXACT [] synonym: "medial geniculate nuclei" EXACT [] synonym: "medial geniculate nucleus" EXACT [] synonym: "corpus geniculatum mediale" EXACT [NIF_GrossAnatomy:birnlex_1670] synonym: "internal geniculate body" RELATED [ncithesaurus:Internal_Geniculate_Body] synonym: "MGB" RELATED [BTO:0002674] xref: FMA:62211 ! Medial geniculate body xref: MA:0000870 ! medial geniculate nucleus xref: NIF_GrossAnatomy:birnlex_1670 ! Medial geniculate body xref: BTO:0002674 ! medial geniculate body xref: EFO:0001968 ! medial geniculate nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: EV:0100218 ! medial geniculate nucleus xref: ABA:MG ! Medial geniculate complex xref: BM:Die-Th-MG ! medial geniculate complex is_a: UBERON:0007692 {source="FMA"} ! nucleus of thalamus relationship: part_of UBERON:0002704 {source="FMA"} ! metathalamus relationship: spatially_disjoint_from UBERON:0002479 {source="ABA"} ! dorsal lateral geniculate nucleus synonym: "nuclei corporis geniculati medialis" EXACT LATIN [FMA:TA, FMA:62211] xref: SCTID:362378001 ! Entire medial geniculate body xref: ncithesaurus:Internal_Geniculate_Body ! Internal Geniculate Body xref: UMLS:C0086596 [Term] id: UBERON:0001928 name: preoptic area def: "Area of the forebrain anterior to the posterior tuberculum and the hypothalamus and ventral to the ventral thalamus[ZFA]." [Wikipedia:Preoptic_area, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "area praeoptica" RELATED [] synonym: "area preoptica" RELATED [] synonym: "preoptic nuclei" EXACT [] synonym: "preoptic region" RELATED [] synonym: "preoptic region of hypothalamus" EXACT [] synonym: "area hypothalamica rostralis" RELATED [BTO:0001796] synonym: "preoptic hypothalamic area" RELATED [BTO:0001796] synonym: "preoptic hypothalamic region" RELATED [BTO:0001796] synonym: "regio hypothalamica anterior" RELATED [BTO:0001796] xref: FMA:62313 ! Preoptic area xref: GAID:644 ! preoptic area xref: NIF_GrossAnatomy:birnlex_1706 ! Preoptic area xref: TAO:0000470 ! preoptic area xref: ZFA:0000470 ! preoptic area xref: BTO:0001796 ! preoptic area xref: EFO:0002523 ! preoptic area xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: MESH:A08.186.211.730.385.357.342.450 ! preoptic area xref: BM:Die-Hy-POA ! preoptic area is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001894 ! diencephalon xref: SCTID:362382004 ! Entire preoptic area synonym: "area preoptica" RELATED LATIN [Wikipedia:Preoptic_area] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/HypothalamicNuclei.PNG property_value: external_definition "Area of the forebrain anterior to the posterior tuberculum and the hypothalamus and ventral to the ventral thalamus. See Figure 7, Atlas of Early Zebrafish Brain Development.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000470", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0007251 name: preoptic nucleus xref: EV:0100226 ! preoptic nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001928 ! preoptic area def: "A nucleus of brain that is part of a preoptic area." [OBOL:automatic] [Term] id: UBERON:0007769 name: medial preoptic region synonym: "medial preoptic area" EXACT [ABA:MPO] xref: MA:0000839 ! medial preoptic region xref: ABA:MPO ! Medial preoptic area is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002272 {source="MA"} ! medial zone of hypothalamus relationship: part_of UBERON:0001928 ! preoptic area [Term] id: UBERON:0002035 name: medial preoptic nucleus def: "The medial preoptic nucleus is bounded laterally by the lateral preoptic nucleus, and medially by the preoptic periventricular nucleus. It releases gonadotropin-releasing hormone, controls copulation in males, and is larger in males than in females.[WP,unvetted]." [Wikipedia:Medial_preoptic_nucleus#Medial_preoptic_nucleus, Wikipedia:Sexually_dimorphic_nucleus] subset: uberon_slim synonym: "medial preoptic hypothalamic nucleus" EXACT [] xref: FMA:67890 ! Medial preoptic nucleus xref: MA:0000840 ! medial preoptic nucleus xref: NIF_GrossAnatomy:birnlex_706 ! Medial preoptic nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: ABA:MPN ! Medial preoptic nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0007769 {source="MA"} ! medial preoptic region relationship: spatially_disjoint_from UBERON:0002634 {source="ABA"} ! anterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002206 {source="ABA"} ! mammillary body relationship: spatially_disjoint_from UBERON:0002706 {source="ABA"} ! posterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0001935 {source="ABA"} ! ventromedial nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002625 {source="ABA"} ! median preoptic nucleus xref: SCTID:369128005 ! Entire medial preoptic nucleus [Term] id: UBERON:0002625 name: median preoptic nucleus def: "The median preoptic nucleus is located along the midline in a position significantly dorsal to the other 3 preoptic nuclei, at least in the macaca fascicularis brain. It wraps around the top (dorsal), front, and bottom (ventral) surfaces of the anterior commissure. The median preoptic nucleus generates thirst. Drinking decreases noradrenaline release in the median preoptic nucleus." [Wikipedia:Preoptic_area#Median_preoptic_nucleus] subset: uberon_slim xref: FMA:62323 ! Median preoptic nucleus xref: NIF_GrossAnatomy:birnlex_1208 ! Median preoptic nucleus xref: ABA:MEPO ! Median preoptic nucleus xref: BM:MPO ! median preoptic nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001928 ! preoptic area relationship: capable_of GO:0048243 {source="Wikipedia"} ! norepinephrine secretion relationship: capable_of GO:2000070 {source="Wikipedia"} ! regulation of response to water deprivation relationship: spatially_disjoint_from UBERON:0002690 {source="ABA"} ! anteroventral periventricular nucleus relationship: spatially_disjoint_from UBERON:0001934 {source="ABA"} ! dorsomedial nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002689 {source="ABA"} ! supraoptic crest relationship: spatially_disjoint_from UBERON:0007626 {source="ABA"} ! subparaventricular zone relationship: spatially_disjoint_from UBERON:0002034 {source="ABA"} ! suprachiasmatic nucleus relationship: spatially_disjoint_from UBERON:0002219 {source="ABA"} ! subfornical organ [Term] id: UBERON:0001931 name: lateral preoptic nucleus def: "The lateral preoptic nucleus is lateral to the medial preoptic nucleus. It also mediates non-REM sleep onset.[WP,unvetted]." [Wikipedia:Preoptic_area#Lateral_preoptic_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lateral preoptic area" EXACT [] synonym: "lateral preoptic hypothalamic nucleus" EXACT [] xref: FMA:62326 ! Lateral preoptic nucleus xref: MA:0000835 ! lateral preoptic area xref: NIF_GrossAnatomy:birnlex_1722 ! Lateral preoptic nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: ABA:LPO ! Lateral preoptic area xref: BM:Die-Hy-LPO ! lateral preoptic area is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002273 ! lateral zone of hypothalamus relationship: capable_of GO:0045188 {source="GO"} ! regulation of circadian sleep/wake cycle, non-REM sleep relationship: spatially_disjoint_from UBERON:0002430 {source="ABA"} ! lateral hypothalamic area relationship: spatially_disjoint_from UBERON:0001933 {source="ABA"} ! retrochiasmatic area relationship: spatially_disjoint_from UBERON:0001906 {source="ABA"} ! subthalamic nucleus relationship: spatially_disjoint_from UBERON:0001907 {source="ABA"} ! zona incerta xref: SCTID:369129002 ! Entire lateral preoptic nucleus [Term] id: UBERON:0002622 name: preoptic periventricular nucleus def: "The preoptic periventricular nucleus is located along the midline and is medial to the medial preoptic nucleus.[WP,unvetted]." [Wikipedia:Preoptic_area#Preoptic_periventricular_nucleus] synonym: "periventricular preoptic nucleus" EXACT [FMA:62324] synonym: "preoptic periventricular hypothalamic nucleus" EXACT [FMA:62324] xref: FMA:62324 ! Preoptic periventricular nucleus xref: NIF_GrossAnatomy:birnlex_1201 ! Preoptic periventricular nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001928 ! preoptic area synonym: "nucleus preopticus periventricularis" EXACT LATIN [FMA:TA, FMA:62324] xref: SCTID:369127000 ! Entire preoptic periventricular nucleus [Term] id: UBERON:0007692 name: nucleus of thalamus comment: todo - consider splitting nucleus and complex synonym: "nuclear complex of thalamus" EXACT [FMA:256693] xref: FMA:256693 ! nucleus of thalamus xref: MA:0002992 ! thalamic nucleus xref: BTO:0002452 ! thalamic nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001897 {source="FMA"} ! thalamus xref: SCTID:279115000 ! Entire nucleus of thalamus synonym: "thalamic nucleus" EXACT [MA:0002992] def: "A nucleus of brain that is part of a thalamus." [OBOL:automatic] [Term] id: UBERON:0002705 name: midline nuclear group def: "The midline nuclear group (or midline thalamic nuclei) a region of the thalamus consisting of the following nuclei: paraventricular nucleus of thalamus (nucleus paraventricularis thalami) - not to be confused with paraventricular nucleus of hypothalamus paratenial nucleus (nucleus parataenialis) reuniens nucleus (nucleus reuniens) rhomboidal nucleus (nucleus commissuralis rhomboidalis) subfascicular nucleus (nucleus subfascicularis) [WP,unvetted]." [Wikipedia:Midline_nuclear_group] subset: uberon_slim synonym: "median nuclei of thalamus" EXACT [FMA:62020] synonym: "midline nuclear group" EXACT [FMA:62020] synonym: "midline nuclei of thalamus" EXACT [FMA:62020] synonym: "periventricular nuclei of thalamus" EXACT [FMA:62020] synonym: "midline nuclear group of thalamus" EXACT [FMA:62020] synonym: "nuclei mediani (thalami)" EXACT [NIF_GrossAnatomy:birnlex_1462] synonym: "midline thalamic group" EXACT [MA:0000864] xref: FMA:62020 ! Midline nuclear group of thalamus xref: NIF_GrossAnatomy:birnlex_1462 ! Midline nuclear group xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: BTO:0002454 ! median nucleus of thalamus xref: MA:0000864 ! midline thalamic group xref: ABA:MTN ! Midline group of the dorsal thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001897 {source="FMA"} ! thalamus relationship: part_of UBERON:0004703 {source="MA"} ! dorsal thalamus synonym: "nuclei mediani thalami" EXACT LATIN [FMA:TA, FMA:62020] xref: SCTID:279163002 ! Entire nucleus of midline nuclear group of thalamus synonym: "nuclei mediani thalami" RELATED LATIN [Wikipedia:Midline_nuclear_group] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png [Term] id: UBERON:0001920 name: paraventricular nucleus of thalamus def: "The nucleus paraventricularis anterior thalami and nuclues paraventricularis posterior thalami, two of the nuclei mediani thalami; they are situated on the dorsomedial wall of the thalamus, juxtaposed to the third ventricle." [Dorlands_Medical_Dictionary:MerckSource] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "paraventricular gray" EXACT [] synonym: "paraventricular nuclei" RELATED PLURAL [] synonym: "paraventricular nuclei of thalamus" EXACT PLURAL [] synonym: "paraventricular thalamic nucleus" EXACT [] xref: FMA:62152 ! Paraventricular nucleus of thalamus xref: MA:0000866 ! paraventricular thalamic nucleus xref: NIF_GrossAnatomy:birnlex_764 ! Paraventricular nucleus of thalamus xref: http://upload.wikimedia.org/wikipedia/en/thumb/e/ef/PVNss.jpg/200px-PVNss.jpg xref: BTO:0002460 ! paraventricular nucleus xref: ABA:PVT ! Paraventricular nucleus of the thalamus xref: BM:Die-Th-Pa ! paraventricular nuclei of thalamus is_a: UBERON:0002308 {source="FMA"} ! nucleus of brain relationship: part_of UBERON:0002705 {source="FMA"} ! midline nuclear group relationship: spatially_disjoint_from UBERON:0002992 {source="ABA"} ! paratenial nucleus synonym: "nuclei paraventriculares thalami" EXACT LATIN [FMA:TA, FMA:62152] xref: SCTID:369163000 ! Entire paraventricular nucleus of thalamus [Term] id: UBERON:0001930 name: paraventricular nucleus of hypothalamus def: "The paraventricular nucleus (PVN) is a neuronal nucleus in the hypothalamus. It contains multiple subpopulations of neurons that are activated by a variety of stressful and/or physiological changes. Many PVH neurons project directly to the posterior pituitary where they release oxytocin or vasopressin into the general circulation. Other PVN neurons control various anterior pituitary functions, while still others directly regulate appetite and autonomic functions in the brainstem and spinal cord. [WP,unvetted]." [Wikipedia:Paraventricular_nucleus_of_hypothalamus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "filiform nucleus" EXACT [] synonym: "paraventricular hypothalamic nucleus" EXACT [] synonym: "paraventricular nucleus" EXACT [] synonym: "nucleus paraventricularis hypothalami" RELATED [BTO:0002476] xref: FMA:62320 ! Paraventricular nucleus of hypothalamus xref: GAID:643 ! paraventricular hypothalamic nucleu xref: MA:0000848 ! paraventricular hypothalamic nucleus xref: NIF_GrossAnatomy:birnlex_1407 ! Paraventricular nucleus of hypothalamus xref: BTO:0002476 ! paraventricular nucleus of hypothalamus xref: EFO:0002469 ! paraventricular nucleus xref: http://upload.wikimedia.org/wikipedia/en/thumb/e/ef/PVNss.jpg/200px-PVNss.jpg xref: MESH:A08.186.211.730.385.357.342.400 ! paraventricular hypothalamic nucleu xref: EV:0100229 ! paraventricular nucleus xref: ABA:PVH ! Paraventricular hypothalamic nucleus xref: BM:Die-Hy-PAH ! paraventricular nucleus of hypothalamus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002271 ! periventricular zone of hypothalamus relationship: spatially_disjoint_from UBERON:0001932 {source="ABA"} ! arcuate nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0001929 {source="ABA"} ! supraoptic nucleus xref: SCTID:369131006 ! Entire paraventricular nucleus synonym: "nuclei paraventricularis hypothalami" RELATED LATIN [Wikipedia:Paraventricular_nucleus_of_hypothalamus] xref: http://upload.wikimedia.org/wikipedia/commons/e/ef/PVNss.jpg [Term] id: UBERON:0001932 name: arcuate nucleus of hypothalamus def: "The arcuate nucleus (or infundibular nucleus) is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence. The arcuate nucleus includes several important populations of neurons, including: Neuroendocrine neurons, Centrally-projecting neurons and Others. [WP,unvetted]." [Wikipedia:Arcuate_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "arcuate hypothalamic nucleus" EXACT [] synonym: "arcuate nucleus" EXACT [] synonym: "arcuate nucleus-2" EXACT [] synonym: "arcuate periventricular nucleus" EXACT [] synonym: "infundibular hypothalamic nucleus" EXACT [] synonym: "infundibular nucleus" EXACT [] synonym: "infundibular periventricular nucleus" EXACT [] synonym: "nucleus arcuatus hypothalami" RELATED [BTO:0002473] synonym: "nucleus infundibularis" RELATED [BTO:0002473] synonym: "nucleus semilunaris" RELATED [BTO:0002473] xref: FMA:62329 ! Arcuate nucleus of hypothalamus xref: GAID:647 ! arcuate nucleus xref: MA:0000847 ! arcuate nucleus xref: NIF_GrossAnatomy:birnlex_1638 ! Arcuate nucleus of hypothalamus xref: ncithesaurus:Arcuate_Nucleus ! Arcuate Nucleus xref: BTO:0002473 ! infundibular nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: MESH:A08.186.211.730.385.357.352.081 ! arcuate nucleu xref: EV:0100230 ! infundibular nucleus xref: ABA:ARH ! Arcuate hypothalamic nucleus xref: BM:HAr ! arcuate nucleus of hypothalamus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002271 ! periventricular zone of hypothalamus relationship: spatially_disjoint_from UBERON:0001930 {source="ABA"} ! paraventricular nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0001929 {source="ABA"} ! supraoptic nucleus synonym: "nucleus arcuatus" EXACT LATIN [FMA:TA, FMA:62329] synonym: "nucleus arcuatus hypothalami" RELATED LATIN [Wikipedia:Arcuate_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/HypothalamicNuclei.PNG xref: UMLS:C0003741 [Term] id: UBERON:0001933 name: retrochiasmatic area comment: This class was created automatically from a combination of ontologies synonym: "retrochiasmatic region" EXACT [] xref: FMA:62330 ! Retrochiasmatic area xref: MA:0000841 ! retrochiasmatic area xref: NIF_GrossAnatomy:birnlex_1569 ! Retrochiasmatic area xref: ABA:RCH ! Retrochiasmatic area is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002272 ! medial zone of hypothalamus relationship: spatially_disjoint_from UBERON:0002430 {source="ABA"} ! lateral hypothalamic area relationship: spatially_disjoint_from UBERON:0001931 {source="ABA"} ! lateral preoptic nucleus relationship: spatially_disjoint_from UBERON:0001906 {source="ABA"} ! subthalamic nucleus relationship: spatially_disjoint_from UBERON:0001907 {source="ABA"} ! zona incerta [Term] id: UBERON:0001934 name: dorsomedial nucleus of hypothalamus def: "The Dorsomedial hypothalamic nucleus is a nucleus of the hypothalamus. It is involved in feeding, drinking, and body weight regulation. [WP,unvetted]." [Wikipedia:Dorsomedial_hypothalamic_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "dorsomedial hypothalamic nucleus" EXACT [] synonym: "dorsomedial nucleus of dorsal hypothalamus" EXACT [] synonym: "dorsomedial nucleus of intermediate hypothalamus" EXACT [] synonym: "nucleus dorsomedialis hypothalamicae intermediae" RELATED [BTO:0002474] xref: FMA:62331 ! Dorsomedial nucleus of hypothalamus xref: GAID:648 ! dorsomedial hypothalamic nucleu xref: MA:0000838 ! dorsomedial hypothalamic nucleus xref: NIF_GrossAnatomy:birnlex_1558 ! Dorsomedial nucleus of hypothalamus xref: BTO:0002474 ! dorsomedial nucleus of intermediate hypothalamus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: MESH:A08.186.211.730.385.357.352.270 ! dorsomedial hypothalamic nucleu xref: EV:0100232 ! dorsomedial nucleus xref: ABA:DMH ! Dorsomedial nucleus of the hypothalamus xref: BM:Die-Hy-DMH ! dorsomedial nucleus of hypothalamus is_a: UBERON:0006568 {source="FMA"} ! hypothalamic nucleus relationship: part_of UBERON:0002555 {source="FMA"} ! intermediate hypothalamic region relationship: part_of UBERON:0002272 {source="MA"} ! medial zone of hypothalamus relationship: capable_of GO:0060259 {source="Wikipedia"} ! regulation of feeding behavior relationship: spatially_disjoint_from UBERON:0002690 {source="ABA"} ! anteroventral periventricular nucleus relationship: spatially_disjoint_from UBERON:0002625 {source="ABA"} ! median preoptic nucleus relationship: spatially_disjoint_from UBERON:0002689 {source="ABA"} ! supraoptic crest relationship: spatially_disjoint_from UBERON:0007626 {source="ABA"} ! subparaventricular zone relationship: spatially_disjoint_from UBERON:0002034 {source="ABA"} ! suprachiasmatic nucleus relationship: spatially_disjoint_from UBERON:0002219 {source="ABA"} ! subfornical organ xref: SCTID:369134003 ! Entire dorsomedial hypothalamic nucleus synonym: "nucleus dorsomedialis hypothalamicae intermediae" RELATED LATIN [Wikipedia:Dorsomedial_hypothalamic_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/HypothalamicNuclei.PNG [Term] id: UBERON:0001935 name: ventromedial nucleus of hypothalamus def: "The ventromedial nucleus (sometimes referred to as the ventromedial hypothalamus) is a nucleus of the hypothalamus. [WP,unvetted]." [Wikipedia:Ventromedial_hypothalamic_nucleus] comment: part of tuberal area in MA subset: uberon_slim synonym: "ventromedial hypothalamic nucleus" EXACT [] synonym: "nucleus ventromedialis hypothalami" RELATED [BTO:0002472] synonym: "ventrolateral hypothalamic nucleus" RELATED [BTO:0002472] synonym: "ventrolateral nucleus of hypothalamus" RELATED [BTO:0002472] synonym: "ventromedial nucleus of hypothalamus." RELATED [BTO:0002472] xref: FMA:62332 ! Ventromedial nucleus of hypothalamus xref: GAID:650 ! ventromedial hypothalamic nucleu xref: MA:0000845 ! ventromedial hypothalamic nucleus xref: NIF_GrossAnatomy:birnlex_1572 ! Ventromedial nucleus of hypothalamus xref: BTO:0002472 ! ventromedial hypothalamic nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: MESH:A08.186.211.730.385.357.352.953 ! ventromedial hypothalamic nucleu xref: EV:0100233 ! ventromedial nucleus xref: ABA:VMH ! Ventromedial hypothalamic nucleus xref: BM:VMH ! ventromedial nucleus of hypothalamus is_a: UBERON:0006568 {source="FMA"} ! hypothalamic nucleus relationship: part_of UBERON:0002555 {source="FMA"} ! intermediate hypothalamic region relationship: spatially_disjoint_from UBERON:0002634 {source="ABA"} ! anterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002206 {source="ABA"} ! mammillary body relationship: spatially_disjoint_from UBERON:0002035 {source="ABA"} ! medial preoptic nucleus relationship: spatially_disjoint_from UBERON:0002706 {source="ABA"} ! posterior nucleus of hypothalamus xref: SCTID:369124007 ! Entire ventromedial hypothalamic nucleus [Term] id: UBERON:0001936 name: tuberomammillary nucleus def: "The tuberomammillary nucleus is a subnucleus of the posterior third of the hypothalamus. It consists of, largely, histaminergic and is involved with the control of arousal, sleep and circadian rhythm. Axons of the tuberomammillary nucleus project primarily to the cerebral cortex, thalamus, basal ganglia, basal forebrain, and hypothalamus. The projections to the cerebral cortex directly increase cortical activation and arousal, and projections to acetylcholinergic neurons of the basal forebrain and dorsal pons do so indirectly, by increasing the release of acetylcholine in the cerebral cortex. [WP,unvetted]." [Wikipedia:Tuberomammillary_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "TM" EXACT [NIF_GrossAnatomy:birnlex_1271] synonym: "caudal magnocellular nucleus" EXACT [NIF_GrossAnatomy:birnlex_1271] synonym: "mammiloinfundibular nucleus" EXACT [NIF_GrossAnatomy:birnlex_1271] synonym: "tuberomammillary hypothalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_1271] synonym: "tuberomammillary nucleus" EXACT [NIF_GrossAnatomy:birnlex_1271] synonym: "tuberomamillary nucleus" RELATED DUBIOUS [EV:0100237] xref: FMA:62335 ! Tuberomammillary nucleus xref: MA:0000853 ! tuberomammillary nucleus xref: NIF_GrossAnatomy:birnlex_1271 ! Tuberomammillary nucleus xref: EV:0100237 ! tuberomamillary nucleus xref: ABA:TM ! Tuberomammillary nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002206 {source="MA"} ! mammillary body relationship: part_of UBERON:0002430 {source="FMA"} ! lateral hypothalamic area relationship: spatially_disjoint_from UBERON:0001938 {source="ABA"} ! lateral mammillary nucleus relationship: spatially_disjoint_from UBERON:0001939 {source="ABA"} ! medial mammillary nucleus relationship: spatially_disjoint_from UBERON:0001940 {source="ABA"} ! supramammillary nucleus xref: SCTID:369122006 ! Entire tuberomammillary nucleus synonym: "mammilloinfundibular nucleus" EXACT [FMA:62335] [Term] id: UBERON:0001937 name: lateral hypothalamic nucleus comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core xref: FMA:62337 ! Lateral hypothalamic nucleus xref: NIF_GrossAnatomy:birnlex_1199 ! Lateral hypothalamic nucleus xref: TAO:0000227 ! lateral hypothalamic nucleus xref: ZFA:0000227 ! lateral hypothalamic nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: EV:0100234 ! lateral nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002430 ! lateral hypothalamic area xref: SCTID:360452004 ! Entire lateral hypothalamic nucleus [Term] id: UBERON:0001938 name: lateral mammillary nucleus comment: This class was created automatically from a combination of ontologies synonym: "lateral mammillary hypothalamic nucleus" EXACT [] synonym: "lateral nucleus of mammillary body" EXACT [] xref: FMA:62341 ! Lateral mammillary nucleus xref: MA:0000850 ! lateral mammillary nucleus xref: NIF_GrossAnatomy:birnlex_1460 ! Lateral mammillary nucleus xref: EV:0100239 ! lateral mamillary nucleus xref: ABA:LM ! Lateral mammillary nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002206 ! mammillary body relationship: spatially_disjoint_from UBERON:0001939 {source="ABA"} ! medial mammillary nucleus relationship: spatially_disjoint_from UBERON:0001940 {source="ABA"} ! supramammillary nucleus relationship: spatially_disjoint_from UBERON:0001936 {source="ABA"} ! tuberomammillary nucleus synonym: "nucleus mammillaris lateralis" EXACT LATIN [FMA:TA, FMA:62341] xref: SCTID:369143007 ! Entire lateral mammillary nucleus [Term] id: UBERON:0001939 name: medial mammillary nucleus comment: This class was created automatically from a combination of ontologies synonym: "internal mammillary nucleus" EXACT [] synonym: "medial nucleus of mammillary body" EXACT [] xref: FMA:62342 ! Medial mammillary nucleus xref: MA:0000851 ! medial mammillary nucleus xref: NIF_GrossAnatomy:birnlex_1299 ! Medial mammillary nucleus xref: EV:0100238 ! medial mamillary nucleus xref: ABA:MM ! Medial mammillary nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002206 ! mammillary body relationship: spatially_disjoint_from UBERON:0001938 {source="ABA"} ! lateral mammillary nucleus relationship: spatially_disjoint_from UBERON:0001940 {source="ABA"} ! supramammillary nucleus relationship: spatially_disjoint_from UBERON:0001936 {source="ABA"} ! tuberomammillary nucleus synonym: "nucleus mammillaris medialis" EXACT LATIN [FMA:TA, FMA:62342] xref: SCTID:369141009 ! Entire medial mammillary nucleus [Term] id: UBERON:0001940 name: supramammillary nucleus comment: This class was created automatically from a combination of ontologies xref: FMA:62347 ! Supramammillary nucleus xref: MA:0000852 ! supramammillary nucleus xref: NIF_GrossAnatomy:birnlex_1479 ! Supramammillary nucleus xref: ABA:SUM ! Supramammillary nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002206 ! mammillary body relationship: spatially_disjoint_from UBERON:0001938 {source="ABA"} ! lateral mammillary nucleus relationship: spatially_disjoint_from UBERON:0001939 {source="ABA"} ! medial mammillary nucleus relationship: spatially_disjoint_from UBERON:0001936 {source="ABA"} ! tuberomammillary nucleus xref: SCTID:369144001 ! Entire supramammillary nucleus [Term] id: UBERON:0001941 name: lateral habenular nucleus comment: This class was created automatically from a combination of ontologies synonym: "lateral habenula" EXACT [] synonym: "nucleus habenulae lateralis" EXACT [NIF_GrossAnatomy:birnlex_1438] synonym: "nucleus habenularis lateralis" EXACT [NIF_GrossAnatomy:birnlex_1438] synonym: "nucleus habenularis lateralis epithalami" EXACT [NIF_GrossAnatomy:birnlex_1438] xref: FMA:62372 ! Lateral habenular nucleus xref: MA:0000831 ! lateral habenular nucleus xref: NIF_GrossAnatomy:birnlex_1438 ! Lateral habenular nucleus xref: BTO:0002699 ! lateral habenular nucleus xref: ABA:LH ! Lateral habenula xref: BM:Die-Epi-Hl ! lateral habenular nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001904 ! habenula relationship: spatially_disjoint_from UBERON:0001942 {source="ABA"} ! medial habenular nucleus relationship: spatially_disjoint_from UBERON:0001905 {source="ABA"} ! pineal body xref: SCTID:361538005 ! Lateral habenular nucleus [Term] id: UBERON:0001942 name: medial habenular nucleus comment: This class was created automatically from a combination of ontologies synonym: "medial habenula" EXACT [] synonym: "nucleus habenulae medialis" EXACT [NIF_GrossAnatomy:birnlex_1431] synonym: "nucleus habenularis medialis" EXACT [NIF_GrossAnatomy:birnlex_1431] synonym: "nucleus habenularis medialis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1431] synonym: "nucleus habenularis medialis epithalami" EXACT [NIF_GrossAnatomy:birnlex_1431] xref: FMA:62373 ! Medial habenular nucleus xref: MA:0000832 ! medial habenular nucleus xref: NIF_GrossAnatomy:birnlex_1431 ! Medial habenular nucleus xref: BTO:0003686 ! medial habenular nucleus xref: ABA:MH ! Medial habenula xref: BM:Die-Epi-HM ! medial habenular nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001904 ! habenula relationship: spatially_disjoint_from UBERON:0001941 {source="ABA"} ! lateral habenular nucleus relationship: spatially_disjoint_from UBERON:0001905 {source="ABA"} ! pineal body [Term] id: UBERON:0006794 ! visual processing part of nervous system name: visual processing part of nervous system comment: This grouping class is primarily to accommodate GO synonym: "optic lobe" RELATED [GAID:1233] subset: grouping_class xref: GAID:1233 ! optic lobe is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0001016 ! nervous system relationship: capable_of GO:0007601 ! visual perception [Term] id: UBERON:0002635 name: regional part of midbrain tegmentum subset: non_informative synonym: "midbrain tegmentum segment" EXACT [FMA:62399] synonym: "segment of midbrain tegmentum" EXACT [NIF_GrossAnatomy:birnlex_1227] xref: FMA:62399 ! Segment of midbrain tegmentum xref: NIF_GrossAnatomy:birnlex_1227 ! Regional part of midbrain tegmentum intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001943 ! midbrain tegmentum def: "A multi-tissue structure that is part of a midbrain tegmentum." [OBOL:automatic] [Term] id: UBERON:0001943 name: midbrain tegmentum def: "Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN10:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]." [Wikipedia:Midbrain_tegmentum, FMA:FMA, ISBN10:0471888893] comment: 'tegmentum' is used generically for the ventral part of the brainstem (ISBN10:0471888893). We use the label 'midbrain tegmentum' to denote the midbrain structure. In NIFSTD tegmentum is a composite structure and there is a separate class for midbrain tegmentum and pontine tegmentum subset: uberon_slim subset: vertebrate_core synonym: "mesencephalic tegmentum" RELATED [VHOG:0001367] synonym: "tegmentum" BROAD [ISBN10:0471888893] synonym: "tegmentum of midbrain" EXACT [] synonym: "tegmentum mesencephali" EXACT LATIN [Wikipedia:Midbrain_tegmentum] xref: EFO:0000921 ! tegmentum xref: FMA:62393 ! Midbrain tegmentum xref: VHOG:0001367 ! tegmentum xref: MA:0000212 ! tegmentum xref: MAT:0000452 ! tegmentum xref: NIF_GrossAnatomy:birnlex_1200 ! Midbrain tegmentum xref: TAO:0000160 ! tegmentum xref: ZFA:0000160 ! tegmentum xref: BTO:0003388 ! tegmentum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b6/Gray712.png/200px-Gray712.png xref: EMAPA:18215 ! tegmentum is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0002298 ! brainstem relationship: develops_from UBERON:0010285 {source="ZFA"} ! midbrain basal plate xref: SCTID:362392007 ! Entire tegmentum of midbrain xref: EHDAA2:0004475 ! tegmentum xref: http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png property_value: homology_notes "Together, our results reveal a shared basic organization in the tegmental domains of the diencephalon and midbrain of developing lamprey, indicating early appearance of the domain in vertebrate phylogeny.[well established][VHOG]" xsd:string {external_class="VHOG:0001367", ontology="VHOG", source="DOI:10.1016/j.brainresbull.2005.05.001 Villar-Cheda B\, Abalo XM\, Anadon R\, Rodicio MC\, The tegmental proliferation region in the sea lamprey. Brain Research Bulletin (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001944 name: pretectal region def: "Region between dorsal thalamus and optic tectum[pub]. It receives binocular sensory input from retinal ganglion cells of the eyes, and is the region responsible for maintaining the pupillary light reflex. [WP,unvetted]." [Wikipedia:Pretectum, ISBN10:0471888893 "Comparative Vertebrate Neuroanatomy\: Evolution and Adaptation"] comment: part of diencephalon in ZFA - modify to adjacent here, supported by pub subset: uberon_slim subset: vertebrate_core synonym: "pretectal area" EXACT [] synonym: "pretectal nuclei" EXACT [] synonym: "pretectum" EXACT [] xref: FMA:62402 ! Pretectal region xref: MA:0001062 ! pretectal region xref: NIF_GrossAnatomy:birnlex_703 ! Pretectal region xref: TAO:0000418 ! pretectum xref: ZFA:0000418 ! pretectum xref: ABA:PRT ! Pretectal region xref: BM:MB-Tec-PT ! pretectum is_a: UBERON:0002308 ! nucleus of brain relationship: adjacent_to UBERON:0004703 {source="ISBN10:0471888893"} ! dorsal thalamus relationship: part_of UBERON:0002314 {source="FMA"} ! midbrain tectum relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus synonym: "area pretectalis" EXACT LATIN [FMA:TA, FMA:62402] synonym: "nuclei pretectales" EXACT LATIN [FMA:TA, FMA:62402] xref: SCTID:416333003 ! Pretectal area [Term] id: UBERON:0002259 name: corpora quadrigemina def: "In the brain, the corpora quadrigemina (Latin for 'quadruplet bodies') are the four colliculi—two inferior, two superior—located on the tectum the dorsal aspect of the midbrain. The corpora quadrigemina are reflex centers involving vision and hearing. [WP,unvetted]. Two pairs of colliculi on the dorsal surface of the midbrain composed of white matter externally and gray matter within, the superior pair containing correlation centers for optic reflexes and the inferior pair containing correlation centers for auditory reflexes[BTO]." [Wikipedia:Corpora_quadrigemina, BTO:0001710] comment: editor note: this section needs worked on for pan-vertebrate consistency. for now we include a mammal specific definition, even though the child terms are applicable across vertebrates subset: uberon_slim synonym: "corpora quadrigemina" EXACT [] synonym: "colliculi" EXACT [MP:0000899] xref: FMA:242157 ! set of colliculi xref: GAID:574 ! corpora quadrigemina xref: MA:0002567 ! corpora quadrigemina xref: ncithesaurus:Corpora_Quadrigemina ! Corpora Quadrigemina xref: BTO:0001710 ! corpora quadrigemina xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Gray709.png/200px-Gray709.png xref: MESH:A08.186.211.132.659.237 ! corpora quadrigemina xref: EV:0100244 ! colliculi is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002314 ! midbrain tectum relationship: develops_from UBERON:0006777 ! tectal plate xref: SCTID:361579006 ! Entire corpora quadrigemina xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png synonym: "set of colliculi" RELATED [FMA:242157] xref: UMLS:C0010087 [Term] id: UBERON:0006777 ! tectal plate name: tectal plate def: "embryologic structure that is formed by two longitudinal eminences, one on each alar plate of the midbrain. These eminences become the superior colliculus and inferior colliculus ( Carpenter-1983 )]" [http://braininfo.rprc.washington.edu/centraldirectory.aspx?type=a&ID=453] comment: The term "tectal plate" (or "quadrigeminal plate") is used to describe the junction of the gray and white matter in the embryo. (NeuroNames ancil-453) synonym: "quadrigeminal plate" EXACT [FMA:77488] xref: FMA:77488 ! tectal plate is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo synonym: "lamina quadrigemina" EXACT LATIN [FMA:TA, FMA:77488] [Term] id: UBERON:0002140 name: parabigeminal nucleus def: "." [Wikipedia:Superior_colliculus#Nucleus_Isthmii.2FParabigeminalis] synonym: "nucleus parabigeminalis" EXACT [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=482] comment: AO notes: in MA this is part of the tegmentum/brainstem xref: FMA:72415 ! Parabigeminal nucleus xref: MA:0001074 ! parabigeminal nucleus xref: NIF_GrossAnatomy:birnlex_1007 ! Parabigeminal nucleus xref: ABA:PBG ! Parabigeminal nucleus xref: BM:PBG ! parabigeminal nucleus xref: VHOG:0001701 ! nucleus isthmi is_a: UBERON:0011214 {source="FMA", source="NIF"} ! nucleus of midbrain tectum relationship: homologous_to ZFA:0000398 {source="ISBN10:0471888893"} ! nucleus isthmi xref: VHOG:0001701 ! nucleus isthmi synonym: "nucleus isthmi" RELATED [VHOG:0001701] property_value: homology_notes "Nucleus isthmi is present in the isthmus in most vertebrates. It is called the parabigeminal nucleus in mammals (reference 1); In sum, our results show that the origin of neurons of some tegmental hindbrain nuclei, namely, nucleus isthmi/superior reticular nucleus and secondary gustatory/viscerosensory nucleus is in the URL (upper rhombic lip), and that the temporal order of cell types produced by the URL and their developmental program are conserved among vertebrate species (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001701", ontology="VHOG", source="ISBN:978-0471210054 Butler AB\, Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.272\, DOI:10.1002/cne.22364 Volkmann K\, Chen YY\, Harris MP\, Wullimann MF\, Köster RW\, The zebrafish cerebellar upper rhombic lip generates tegmental hindbrain nuclei by long-distance migration in an evolutionary conserved manner. The Journal of Comparative Neurology (2010)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002314 ! midbrain tectum name: midbrain tectum def: "Dorsal part of the midbrain, consisting of the superior and inferior colliculi and the pretectal nuclei [MM, NIF]. The tectum is a region of the brain, specifically the dorsal part of the mesencephalon (midbrain). This is contrasted with the tegmentum, which refers to the region ventral to the ventricular system. It is derived in embryonic development from the alar plate of the neural tube. [WP,unvetted]." [NIF_GrossAnatomy:birnlex_1032, Wikipedia:Midbrain_tectum] comment: In adult humans it is present only in the mesencephalon as the inferior and the superior colliculi[WP]. subset: uberon_slim synonym: "neuraxis tectum" EXACT [] synonym: "tectum" EXACT [] synonym: "mesencephalic tectum" EXACT [ZFA:0000445] synonym: "tectum mesencephali" EXACT [BTO:0001793] xref: EFO:0000920 ! tectum xref: FMA:83902 ! Midbrain tectum xref: MA:0000211 ! tectum xref: MAT:0000451 ! tectum xref: NIF_GrossAnatomy:birnlex_1032 ! Midbrain tectum xref: VHOG:0001388 ! tectum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Gray685.png/200px-Gray685.png xref: BTO:0001793 ! tectum mesencephali xref: EMAPA:19051 ! tectum xref: BM:MB-Tec ! tectum is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001891 ! midbrain relationship: develops_from UBERON:0005882 ! alar plate xref: ncithesaurus:Tectum_Mesencephali ! Tectum Mesencephali xref: SCTID:362394008 ! Entire tectum xref: EHDAA2:0004474 ! tectum synonym: "t. mesencephali" RELATED LATIN [Wikipedia:Midbrain_tectum] xref: TAO:0001353 ! mesencephalic tectum xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Gray685.png property_value: homology_notes "The tectum - a multisensory, topologically mapped structure in the roof of the midbrain presents a remarkable degree of conservation in all vertebrate radiations; although it varies in the extent of its development in different vertebrate classes, there is considerable evidence now to deem its layered structure, its cell types, and its hodological pattern as homologous in all vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0001388", ontology="VHOG", source="DOI:10.1371/journal.pone.0003582 Maximino C\, Evolutionary Changes in the Complexity of the Tectum of Nontetrapods: A Cladistic Approach. PLoS ONE (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0039433 [Term] id: UBERON:0001945 name: superior colliculus def: "Part of the midbrain tectum consisting of paired bodies that sit caudal to the thalamus and surround the pineal gland in the mesencephalon of vertebrate brains. It comprises the rostral aspect of the midbrain, posterior to the periaqueductal gray and adjacent superior the inferior colliculus. The inferior and superior colliculi are known collectively as the corpora quadrigemina (Latin, quadruplet bodies). It consists of several identified cellular layers and also comprises the brachium of the superior colliculus and commissure of superior colliculus [Wikipedia.org and Neuronames (MM)]." [Wikipedia:Superior_colliculus, NIF_GrossAnatomy:birnlex_1040] comment: The term SC is used when discussing mammals, and OT for other vertebrates[WP]. The tectum is a layered structure, with a number of layers that vary by species. The superficial layers are sensory-related, and receive input from the eyes as well as other sensory systems.[1] The optic tectum is one of the fundamental components of the vertebrate brain, existing across the full range of species from hagfish to human.[4] (See the brain article for background.) Some aspects of the structure are very consistent, including a structure composed of a number of layers, with a dense input from the optic nerve to the superficial layers and another strong input conveying somatosensory input to deeper layers. Other aspects are highly variable, such as the total number of layers (from 3 in the African lungfish to 15 in the goldfish[5]), and the number of different types of cells (from 2 in the lungfish to 27 in the house sparrow[5]). In hagfish, lamprey, and shark it is a relatively small structure, but in teleost fish it is greatly expanded, in some cases becoming the largest structure in the brain. (See the adjoining drawing of a codfish brain.) In amphibians, reptiles, and especially birds it is also a very significant component, but in mammals it is dwarfed by the massive expansion of the cerebral cortex. subset: uberon_slim subset: vertebrate_core synonym: "anterior colliculus" EXACT [] synonym: "anterior corpus quadrigeminum" EXACT [] synonym: "cranial colliculus" EXACT [] synonym: "dorsal midbrain" RELATED [] synonym: "optic tectum" RELATED [] synonym: "tectal lobe" RELATED [] synonym: "optic lobe" RELATED [] synonym: "tectum" RELATED [] synonym: "tectum opticum" RELATED [] synonym: "optic tectum" EXACT SENSU [ZFA:0000445, Wikipedia:Superior_colliculus] synonym: "corpora bigemina" RELATED [] xref: ZFA:0000445 ! optic tectum xref: XAO:0003226 ! optic tectum xref: FMA:62403 ! Superior colliculus xref: GAID:576 ! superior colliculus xref: MA:0001068 ! superior colliculus xref: NIF_GrossAnatomy:birnlex_1040 ! Superior colliculus xref: EFO:0002474 ! superior colliculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Cn3nucleus.png/200px-Cn3nucleus.png xref: BTO:0000965 ! optic lobe xref: MESH:A08.186.211.132.659.237.816 ! superior colliculus xref: EV:0100245 ! superior colliculi xref: BM:MB-Tec-SC ! superior colliculus is_a: UBERON:0006794 ! visual processing part of nervous system is_a: UBERON:0002966 ! regional part of midbrain tectum relationship: part_of UBERON:0002259 ! corpora quadrigemina xref: AAO:0010609 ! optic tectum xref: TAO:0000445 ! optic tectum xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Cn3nucleus.png property_value: external_definition "The brain structure where the two separate inputs from the two eyes are combined into a single, integrated map.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010609", date_retrieved="2012-06-20", source="PMID:17952453"} property_value: external_definition "The roof of the midbrain, morphologically visible by the end of the segmentation period. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000445", date_retrieved="2012-08-14", source="ZFIN:curator"} relationship: in_lateral_side_of UBERON:0002314 {source="FMA-abduced-lr"} ! midbrain tectum [Term] id: UBERON:0001946 name: inferior colliculus def: "The inferior colliculi together with the superior colliculi form the eminences of the corpora quadrigemina, and also part of the tectal region of the midbrain. The inferior colliculus lies caudal to its counterpart - the superior colliculus - above the trochlear nerve, and at the base of the projection of the medial geniculate nucleus (MGN) and the lateral geniculate nucleus (LGN). The inferior colliculus is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subnuclei. [WP,unvetted]." [Wikipedia:Inferior_colliculus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "caudal colliculus" EXACT [] synonym: "posterior colliculus" EXACT [] synonym: "posterior corpus quadrigeminum" EXACT [] synonym: "inferior colliculi" EXACT PLURAL [EV:0100246] xref: FMA:62404 ! Inferior colliculus xref: GAID:575 ! inferior colliculus xref: MA:0001067 ! inferior colliculus xref: NIF_GrossAnatomy:birnlex_806 ! Inferior colliculus xref: EFO:0002465 ! inferior colliculus xref: MESH:A08.186.211.132.659.237.364 ! inferior colliculus xref: EV:0100246 ! inferior colliculi xref: ABA:IC ! Inferior colliculus is_a: UBERON:0002966 ! regional part of midbrain tectum relationship: part_of UBERON:0002259 ! corpora quadrigemina synonym: "colliculus inferior" RELATED LATIN [Wikipedia:Inferior_colliculus] xref: http://upload.wikimedia.org/wikipedia/commons/2/26/Gray711.png relationship: in_lateral_side_of UBERON:0002314 {source="FMA-abduced-lr"} ! midbrain tectum [Term] id: UBERON:0002580 name: brachium of superior colliculus def: "The brachium of superior colliculus (or superior brachium) extends lateralward from the superior colliculus, and, passing between the pulvinar and medial geniculate body, is partly continued into an eminence called the lateral geniculate body, and partly into the optic tract. [WP,unvetted]." [Wikipedia:Brachium_of_superior_colliculus] subset: uberon_slim synonym: "superior brachium" EXACT [FMA:72417] synonym: "superior collicular brachium" EXACT [FMA:72417] synonym: "superior colliculus brachium" EXACT [FMA:72417] synonym: "superior quadrigeminal brachium" EXACT [FMA:72417] xref: FMA:72417 ! Brachium of superior colliculus xref: NIF_GrossAnatomy:birnlex_1065 ! Brachium of superior colliculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Human_brainstem-thalamus_posterior_view_description.JPG/200px-Human_brainstem-thalamus_posterior_view_description.JPG xref: BM:MB-BSC ! brachium of inferior colliculus (also: UBERON:0003025 'brachium of inferior colliculus') is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001945 ! superior colliculus synonym: "brachium colliculi superioris" RELATED LATIN [Wikipedia:Brachium_of_superior_colliculus] xref: http://upload.wikimedia.org/wikipedia/commons/2/29/Human_brainstem-thalamus_posterior_view_description.JPG [Term] id: UBERON:0003025 name: brachium of inferior colliculus def: "The Brachium of inferior colliculus (or inferior brachium) carries auditory afferent fibers from the inferior colliculus of the mesencephalon to the medial geniculate nucleus. [WP,unvetted]." [Wikipedia:Brachium_of_inferior_colliculus] subset: uberon_slim synonym: "brachium of medial geniculate" EXACT [FMA:71114] synonym: "inferior brachium" EXACT [FMA:71114] synonym: "inferior collicular brachium" EXACT [FMA:71114] synonym: "inferior colliculus brachium" EXACT [FMA:71114] synonym: "inferior quadrigeminal brachium" EXACT [FMA:71114] synonym: "peduncle of inferior colliculus" EXACT [FMA:71114] xref: FMA:71114 ! Brachium of inferior colliculus xref: NIF_GrossAnatomy:birnlex_929 ! Brachium of inferior colliculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Human_brainstem-thalamus_posterior_view_description.JPG/200px-Human_brainstem-thalamus_posterior_view_description.JPG xref: BM:MB-BSC ! brachium of inferior colliculus (also: UBERON:0002580 'brachium of superior colliculus') is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001946 ! inferior colliculus synonym: "brachium colliculi inferioris" RELATED LATIN [Wikipedia:Brachium_of_inferior_colliculus] xref: http://upload.wikimedia.org/wikipedia/commons/2/29/Human_brainstem-thalamus_posterior_view_description.JPG [Term] id: UBERON:0002583 name: commissure of superior colliculus def: "A commissure that is part of a superior colliculus [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "commissure of superior colliculi" EXACT [FMA:72418] synonym: "superior colliculus commissure" EXACT [FMA:72418] synonym: "anterior colliculus commissure" EXACT [OBOL:automatic] synonym: "anterior corpus quadrigeminum commissure" EXACT [OBOL:automatic] synonym: "commissure of anterior colliculus" EXACT [OBOL:automatic] synonym: "commissure of anterior corpus quadrigeminum" EXACT [OBOL:automatic] synonym: "commissure of cranial colliculus" EXACT [OBOL:automatic] synonym: "commissure of optic tectum" EXACT [OBOL:automatic] synonym: "cranial colliculus commissure" EXACT [OBOL:automatic] synonym: "optic tectum commissure" EXACT [OBOL:automatic] synonym: "intertectal commissure" EXACT SENSU [ZFA:0000684] xref: FMA:72418 ! Commissure of superior colliculus xref: NIF_GrossAnatomy:birnlex_1073 ! Commissure of superior colliculus xref: ZFA:0000684 ! intertectal commissure xref: BM:MB-Tec-SC-SCX ! commissure of superior colliculus is_a: UBERON:0001020 ! commissure intersection_of: UBERON:0001020 ! commissure intersection_of: part_of UBERON:0001945 ! superior colliculus relationship: part_of UBERON:0001945 ! superior colliculus xref: SCTID:369258008 ! Entire commissure of superior colliculus xref: TAO:0000684 ! intertectal commissure [Term] id: UBERON:0006783 ! layer of superior colliculus name: layer of superior colliculus def: "The microstructure of the optic tectum / superior colliculus varies across species. As a general rule, there is always a clear distinction between superficial layers, which receive input primarily from the visual system and show primarily visual responses, and deeper layers, which receive many types of input and project to numerous motor-related brain areas. The distinction between these two zones is so clear and consistent that some anatomists have suggested that they should be considered separate brain structures. In mammals, neuroanatomists conventionally identify seven layers[WP]." [Wikipedia:Superior_colliculus#Neural_circuit] xref: NIF_GrossAnatomy:nlx_anat_1005033 ! Cytoarchitectural part of superior colliculus intersection_of: UBERON:0004923 ! organ component layer intersection_of: part_of UBERON:0001945 ! superior colliculus [Term] id: UBERON:0006786 name: white matter of superior colliculus synonym: "white matter layer of superior colliculus" EXACT [FMA:83899] xref: FMA:83899 ! white matter layer of superior colliculus xref: NIF_GrossAnatomy:birnlex_1023 ! Predominantly white regional part of superior colliculus intersection_of: UBERON:0002316 ! white matter of neuraxis intersection_of: part_of UBERON:0001945 ! superior colliculus [Term] id: UBERON:0006785 name: gray matter of superior colliculus xref: FMA:77870 ! gray matter layer of superior colliculus synonym: "gray matter layer of superior colliculus" EXACT [FMA:77870] intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: part_of UBERON:0001945 ! superior colliculus [Term] id: UBERON:0006791 ! superficial layer of superior colliculus name: superficial layer of superior colliculus xref: ZFA:0000686 ! superficial grey and white zone xref: BM:MB-Tec-SCS ! superficial layer of superior colliculus is_a: UBERON:0006783 ! layer of superior colliculus xref: TAO:0000686 ! superficial grey and white zone synonym: "superficial grey and white zone" RELATED [TAO:0000686] synonym: "superficial grey and white zones" RELATED PLURAL [TAO:0000686] [Term] id: UBERON:0006792 ! intermediate layer of superior colliculus name: intermediate layer of superior colliculus xref: ZFA:0000327 ! central zone xref: BM:MB-Tec-SCI ! intermediate layer of superior colliculus intersection_of: UBERON:0006783 ! layer of superior colliculus intersection_of: adjacent_to UBERON:0006791 ! superficial layer of superior colliculus intersection_of: adjacent_to UBERON:0006793 ! deep layer of superior colliculus xref: TAO:0000327 ! central zone synonym: "central zone" RELATED [TAO:0000327] def: "A layer of superior colliculus that adjacent_to a superficial layer of superior colliculus and adjacent_to a deep layer of superior colliculus." [OBOL:automatic] [Term] id: UBERON:0006793 ! deep layer of superior colliculus name: deep layer of superior colliculus xref: BM:MB-Tec-SCD ! deep layer of superior colliculus is_a: UBERON:0006783 ! layer of superior colliculus [Term] id: UBERON:0006780 name: zonal layer of superior colliculus def: "a thin layer consisting of small myelinated axons together with marginal and horizontal cells." [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "lamina I of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "layer I of superior colliculus" EXACT [FMA:72406] synonym: "stratum zonale of superior colliculus" EXACT [FMA:72406] xref: FMA:72406 ! zonal layer of superior colliculus xref: ABA:SCzo ! Superior colliculus, zonal layer is_a: UBERON:0006785 ! gray matter layer of superior colliculus is_a: UBERON:0006791 ! superficial layer of superior colliculus relationship: spatially_disjoint_from UBERON:0006779 {source="ABA"} ! superficial white layer of superior colliculus relationship: spatially_disjoint_from UBERON:0006120 {source="ABA"} ! superior colliculus superficial gray layer synonym: "lamina colliculi superioris i" EXACT LATIN [FMA:TA, FMA:72406] [Term] id: UBERON:0006120 name: superior colliculus superficial gray layer synonym: "superior colliculus superficial gray layer" EXACT [NIF_GrossAnatomy:nlx_anat_1005034] synonym: "layer II of superior colliculus" EXACT [FMA:72407] synonym: "lamina II of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "stratum griseum superficiale of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "outer gray layer of superior colliculus" EXACT [FMA:72407] synonym: "superficial grey layer of superior colliculus" EXACT [FMA:72407] synonym: "superficial gray layer of superior colliculus" EXACT [FMA:72407] xref: FMA:72407 ! superficial gray layer of superior colliculus xref: NIF_GrossAnatomy:nlx_anat_1005034 ! Superior colliculus superficial gray layer xref: ABA:SCsg ! Superior colliculus, superficial gray layer is_a: UBERON:0006785 ! gray matter layer of superior colliculus is_a: UBERON:0006791 ! superficial layer of superior colliculus relationship: spatially_disjoint_from UBERON:0006779 {source="ABA"} ! superficial white layer of superior colliculus relationship: spatially_disjoint_from UBERON:0006780 {source="ABA"} ! zonal layer of superior colliculus synonym: "lamina colliculi superioris ii" EXACT LATIN [FMA:TA, FMA:72407] synonym: "stratum griseum superficiale colliculi superioris" EXACT LATIN [FMA:TA, FMA:72407] [Term] id: UBERON:0006779 name: superficial white layer of superior colliculus def: "superficial white matter layer of superior collilculus that consists mainly of axions from the optic nerve." [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "layer III of superior colliculus" EXACT [FMA:71112] synonym: "lamina III of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "optic layer" EXACT [FMA:71112] synonym: "optic layer of superior colliculus" EXACT [FMA:71112] xref: FMA:71112 ! superficial white layer of superior colliculus xref: ABA:SCop ! Superior colliculus, optic layer is_a: UBERON:0006786 ! white matter layer of superior colliculus is_a: UBERON:0006791 ! superficial layer of superior colliculus relationship: spatially_disjoint_from UBERON:0006120 {source="ABA"} ! superior colliculus superficial gray layer relationship: spatially_disjoint_from UBERON:0006780 {source="ABA"} ! zonal layer of superior colliculus synonym: "stratum opticum colliculi superioris" EXACT LATIN [FMA:TA, FMA:71112] synonym: "lamina colliculi superioris iii" EXACT LATIN [FMA:TA, FMA:71112] [Term] id: UBERON:0006782 name: stratum lemnisci of superior colliculus xref: FMA:72408 ! stratum lemnisci of superior colliculus is_a: UBERON:0006785 ! gray matter layer of superior colliculus [Term] id: UBERON:0006788 name: middle gray layer of superior colliculus subset: vertebrate_core synonym: "intermediate gray layer" EXACT [FMA:72409] synonym: "intermediate grey layer of superior colliculus" EXACT [FMA:72409] synonym: "layer IV of superior colliculus" EXACT [FMA:72409] synonym: "lamina IV of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "stratum griseum intermediale of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] xref: FMA:72409 ! middle gray layer of superior colliculus xref: ZFA:0001350 ! stratum griseum centrale is_a: UBERON:0006785 ! gray matter layer of superior colliculus is_a: UBERON:0006792 ! intermediate layer of superior colliculus synonym: "lamina colliculi superioris iv" EXACT LATIN [FMA:TA, FMA:72409] synonym: "stratum griseum intermedium colliculi superioris" EXACT LATIN [FMA:TA, FMA:72409] xref: TAO:0001350 ! stratum griseum centrale synonym: "stratum griseum centrale" RELATED [TAO:0001350] [Term] id: UBERON:0006787 name: middle white layer of superior colliculus subset: vertebrate_core synonym: "intermediate white layer" EXACT [FMA:71113] synonym: "intermediate white layer of superior colliculus" EXACT [FMA:71113] synonym: "layer V of superior colliculus" EXACT [FMA:71113] synonym: "lamina V of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "stratum album intermediale of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] xref: FMA:71113 ! middle white layer of superior colliculus xref: ZFA:0001351 ! stratum album centrale is_a: UBERON:0006786 ! white matter layer of superior colliculus is_a: UBERON:0006792 ! intermediate layer of superior colliculus synonym: "stratum medullare intermedium colliculi superioris" EXACT LATIN [FMA:TA, FMA:71113] synonym: "lamina colliculi superioris v" EXACT LATIN [FMA:TA, FMA:71113] xref: TAO:0001351 ! stratum album centrale synonym: "stratum album centrale" RELATED [TAO:0001351] [Term] id: UBERON:0006789 name: deep gray layer of superior colliculus synonym: "deep grey layer of superior colliculus" EXACT [FMA:72410] synonym: "layer VI of superior colliculus" EXACT [FMA:72410] synonym: "lamina VI of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "stratum griseum profundum of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] xref: FMA:72410 ! deep gray layer of superior colliculus is_a: UBERON:0006785 ! gray matter layer of superior colliculus is_a: UBERON:0006793 ! deep layer of superior colliculus synonym: "stratum griseum profundum colliculi superioris" EXACT LATIN [FMA:TA, FMA:72410] synonym: "lamina colliculi superioris vi" EXACT LATIN [FMA:TA, FMA:72410] [Term] id: UBERON:0006790 name: deep white layer of superior colliculus def: "deep white matter layer of superior collilculus that consists entirely of fibers." [Wikipedia:Superior_colliculus#Neural_circuit] subset: vertebrate_core synonym: "layer VII of superior colliculus" EXACT [FMA:72416] synonym: "lamina VII of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] synonym: "stratum album profundum of superior colliculus" EXACT [Wikipedia:Superior_colliculus#Neural_circuit] xref: FMA:72416 ! deep white layer of superior colliculus xref: ZFA:0000494 ! deep white zone is_a: UBERON:0006786 ! white matter layer of superior colliculus is_a: UBERON:0006793 ! deep layer of superior colliculus synonym: "lamina colliculi superioris vii" EXACT LATIN [FMA:TA, FMA:72416] xref: TAO:0000494 ! deep white zone synonym: "deep white zone" RELATED [TAO:0000494] [Term] id: UBERON:0006795 name: arthropod optic lobe def: "A region of the adult brain that processes the visual information from the compound eyes." [FBC:gg, ISBN:978-3-11-014898-5] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology synonym: "optic lobe" RELATED SENSU [FBbt:00003701] xref: FBbt:00003701 ! optic lobe is_a: UBERON:0006794 ! visual processing part of nervous system relationship: part_of UBERON:0000955 ! brain relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0006796 name: cephalopod optic lobe def: "Large lobes of the brain associated with the eyes. In octopods and some squids the optic lobes may be separated from the rest of the brain by an optic stalk of varying length. In Octopus the optic lobes contain 92 million cells compared with only 42 million in the main central mass of the brain (J. Young, 1963) ." [http://tolweb.org/accessory/Cephalopoda_Glossary?acc_id=587] synonym: "optic lobe" RELATED SENSU [] is_a: UBERON:0006794 ! visual processing part of nervous system relationship: part_of UBERON:0000955 ! brain [Term] id: UBERON:0001947 name: red nucleus def: "The red nucleus is a structure in the rostral midbrain involved in motor coordination. It comprises a caudal magnocellular and a rostral parvocellular part. [WP,unvetted]." [Wikipedia:Red_nucleus] comment: Function notes: in animals without a significant corticospinal tract, gait is mainly controlled by the red nucleus. subset: uberon_slim synonym: "nucleus ruber" EXACT [TAO:0000552] xref: FMA:62407 ! Red nucleus xref: GAID:586 ! red nucleu xref: MA:0001063 ! red nucleus xref: NIF_GrossAnatomy:birnlex_1478 ! Red nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Cn3nucleus.png/200px-Cn3nucleus.png xref: MESH:A08.186.211.132.659.822.642 ! red nucleu xref: EV:0100248 ! red nucleus xref: ABA:RN ! Red Nucleus xref: BM:MB-RN ! red nucleus xref: TAO:0000552 ! nucleus ruber xref: ZFA:0000552 ! nucleus ruber is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 {source="FMA"} ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus xref: SCTID:279287006 ! Entire red nucleus xref: EHDAA2:0004706 ! red nucleus synonym: "nucleus ruber" RELATED LATIN [Wikipedia:Red_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Cn3nucleus.png [Term] id: UBERON:0001949 name: gingival epithelium def: "A stratified squamous epithelium consisting of a basal layer; it is keratinized or parakeratinized[BTO]." [BTO:0004998] comment: In humans: 15% orthokeratinized, 75% parakeratinized, 10% non-keratinized; diurnal; decreased keratinization with age. Note that in FMA this is classified as keratinized squamous - this perhaps refers to the epithelium of the attached or free gingiva synonym: "epithelium of gingiva" EXACT [] synonym: "epithelial tissue of gingiva" EXACT [OBOL:automatic] synonym: "gingiva epithelial tissue" EXACT [OBOL:automatic] synonym: "gingiva epithelium" EXACT [OBOL:automatic] xref: BTO:0004998 ! gingival epithelium xref: FMA:62423 ! Gingival epithelium xref: MA:0001576 ! gingival epithelium xref: ncithesaurus:Gingival_Epithelium ! Gingival Epithelium is_a: UBERON:0006915 ! stratified squamous epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001828 ! gingiva relationship: part_of UBERON:0001828 ! gingiva xref: UMLS:C1179154 [Term] id: UBERON:0001951 name: epithelium of nasopharynx alt_id: UBERON:0003237 def: "An epithelium that is part of a nasopharynx [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "nasopharynx epithelium" EXACT [] synonym: "epithelial tissue of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "epithelial tissue of nasopharynx" EXACT [OBOL:automatic] synonym: "epithelial tissue of rhinopharynx" EXACT [OBOL:automatic] synonym: "epithelium of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "epithelium of rhinopharynx" EXACT [OBOL:automatic] synonym: "nasal part of pharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "nasal part of pharynx epithelium" EXACT [OBOL:automatic] synonym: "nasopharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "rhinopharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "rhinopharynx epithelium" EXACT [OBOL:automatic] xref: FMA:62452 ! Epithelium of nasopharynx xref: VHOG:0001038 ! nasopharynx epithelium xref: MA:0001865 ! nasopharynx epithelium xref: EHDAA:7090 ! epithelium xref: ncithesaurus:Nasopharynx_Epithelium ! Nasopharynx Epithelium xref: EHDAA2:0001241 ! nasopharynx epithelium xref: BTO:0004480 ! nasopharynx epithelium xref: EMAPA:17672 ! epithelium of nasopharynx of upper of respiratory tract is_a: UBERON:0000485 ! simple columnar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0003929 {source="EHDAA2"} ! gut epithelium xref: UMLS:C1179157 [Term] id: UBERON:0001952 name: epithelium of oropharynx def: "An epithelium that is part of a oropharynx [Automatically generated definition]." [OBOL:automatic] comment: Histology/AO notes: Composition varies with species and time. This is classified as nonkeratinizing stratified squamous in FMA, unilaminar in EHDAA2; the majority of the pharyngeal epithelium is unilaminar in zebrafish synonym: "oropharyngeal epithelium" EXACT [] synonym: "oropharynx epithelium" EXACT [MA:0001605] synonym: "oropharynx epithelial tissue" EXACT [OBOL:automatic] xref: FMA:62453 ! Epithelium of oropharynx xref: MA:0001605 ! oropharynx epithelium xref: ncithesaurus:Oropharynx_Epithelium ! Oropharynx Epithelium xref: EHDAA2:0004083 ! oropharynx epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001729 ! oropharynx relationship: part_of UBERON:0003929 {source="EHDAA2"} ! gut epithelium xref: UMLS:C1179158 [Term] id: UBERON:0002421 name: hippocampal formation def: "Hippocampus (proper) plus dentate gyrus and subiculum[definition derived from NIF comments and ontology alignment]." [UBERON:cjm] comment: Usage notes: The term hippocampus is often used synonymously with hippocampal formation which consists of the hippocampus proper or Cornu Ammonis, the dentate gyrus and the subiculum[NIF]. BTO:0000601 is placed here since it includes the DG. GO also includes dentate gyrus development as part of hippocampus development, so we assume when GO says "hippocampus" it means "hippocampal formation". In ABA HPF = (.. subiculum) + HIP, HIP = DG + AH. subset: uberon_slim synonym: "archipallium" RELATED [MA:0000189] synonym: "hippocampus (crosby)" EXACT [] synonym: "hippocampus" NARROW [GO:0021766, BTO:0000601] synonym: "major hippocampus" RELATED [BTO:0000601] synonym: "primal cortex" RELATED [MA:0000189] xref: FMA:74038 ! Hippocampal formation xref: MA:0000189 ! hippocampal formation xref: NIF_GrossAnatomy:birnlex_715 ! Hippocampal formation xref: BTO:0000601 ! hippocampus xref: ABA:HPF ! Hippocampal formation xref: BM:Tel-HF ! hippocampal formation is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000203 {source="GO", source="ISBN10:0471888893"} ! pallium relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia:Hippocampus"} ! Mammalia relationship: spatially_disjoint_from UBERON:0001950 {source="ABA"} ! neocortex relationship: spatially_disjoint_from UBERON:0002264 {source="ABA"} ! olfactory bulb xref: SCTID:422867004 ! Structure of hippocampal formation [Term] id: UBERON:0001954 name: Ammon's horn alt_id: UBERON:0004165 alt_id: UBERON:0003940 def: "A paired structure, with mirror-image halves in the left and right sides of the brain. The hippocampus is closely associated with the cerebral cortex, and in primates is located in the medial temporal lobe, underneath the cortical surface. It is shaped like a curved tube[WP]." [Wikipedia:Hippocampus] comment: WP: Non-mammalian species do not have a brain structure that looks like the mammalian hippocampus, but they have one that is considered homologous to it. The hippocampus, as pointed out above, is essentially the medial edge of the cortex. Only mammals have a fully developed cortex, but the structure it evolved from, called the pallium, is present in all vertebrates, even the most primitive ones such as the lamprey or hagfish.[82] The pallium is usually divided into three zones: medial, lateral, and dorsal. The medial pallium forms the precursor of the hippocampus. It does not resemble the hippocampus visually, because the layers are not warped into an S shape or enwrapped by the dentate gyrus, but the homology is indicated by strong chemical and functional affinities. There is now evidence that these hippocampal-like structures are involved in spatial cognition in birds, reptiles, and fish. In birds, the correspondence is sufficiently well established that most anatomists refer to the medial pallial zone as the "avian hippocampus". The story for fish is more complex. In teleost fish (which make up the great majority of existing species), the forebrain is distorted in comparison to other types of vertebrates: most neuroanatomists believe that the teleost forebrain is essentially everted, like a sock turned inside-out, so that structures that lie in the interior, next to the ventricles, for most vertebrates, are found on the outside in teleost fish, and vice versa.[86] One of the consequences of this is that the medial pallium ("hippocampal" zone) of a typical vertebrate is thought to correspond to the lateral pallium of a typical fish. Several types of fish (particularly goldfish) have been shown experimentally to have strong spatial memory abilities, even forming "cognitive maps" of the areas they inhabit.[80] There is evidence that damage to the lateral pallium impairs spatial memory. subset: uberon_slim synonym: "hippocampus" RELATED [MA:0000191] synonym: "hippocampus major" EXACT [] synonym: "hippocampus proper" EXACT [] synonym: "ammon horn" EXACT [NIF_GrossAnatomy:birnlex_721] synonym: "ammon gyrus" EXACT [GO:0021541] synonym: "cornu ammonis" RELATED [GO:0021541] synonym: "Ammon's horn" EXACT [GO:0021541] xref: EFO:0000530 ! hippocampus xref: FMA:62493 ! Hippocampus xref: GAID:623 ! hippocampus xref: VHOG:0001177 ! hippocampus xref: MA:0000191 ! hippocampus xref: MAT:0000114 ! hippocampus xref: MIAA:0000114 ! hippocampus xref: NIF_GrossAnatomy:birnlex_721 ! Hippocampus xref: OpenCyc:Mx4rv3piFJwpEbGdrcN5Y29ycA xref: ncithesaurus:Hippocampus ! Hippocampus xref: ncithesaurus:Cornu_Ammonis ! Cornu Ammonis xref: OpenCyc:Mx4rv3piFJwpEbGdrcN5Y29ycA ! hippocampus xref: EMAPA:19039 ! hippocampus of cerebral cortex xref: EMAPA:19148 ! hippocampus of forebrain xref: MESH:A08.186.211.577.405 ! hippocampus xref: EV:0100180 ! hippocampus xref: BTO:0003705 ! cornu ammonis xref: ABA:CA ! Ammon's Horn xref: BM:Tel-CAM ! cornu ammonis xref: http://scalablebrainatlas.incf.org/services/thumbnail.php?template=ABA07&size=L&dim=2d3d&format=png®ion=CA is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000349 {source="FMA"} ! limbic system relationship: part_of UBERON:0002600 {source="FMA"} ! limbic lobe relationship: part_of UBERON:0002421 {source="ABA"} ! hippocampal formation relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia:Hippocampus"} ! Mammalia relationship: spatially_disjoint_from UBERON:0001885 {source="ABA"} ! dentate gyrus of hippocampal formation relationship: spatially_disjoint_from UBERON:0002601 {source="ABA"} ! fasciolar gyrus synonym: "hippocampus proprius" EXACT LATIN [FMA:TA, FMA:62493] property_value: has_relational_adjective "hippocampal" xsd:string xref: EHDAA2:0004443 ! hippocampus xref: http://upload.wikimedia.org/wikipedia/commons/2/2e/Gray739-emphasizing-hippocampus.png xref: SCTID:361561007 ! Entire hippocampus (also: UBERON:0003876 'subdivision of hippocampus') xref: UMLS:C0019564 [Term] id: UBERON:0003876 name: subdivision of hippocampus comment: do not include ABA:HIP synonym: "subdivision of hippocampus" EXACT [] synonym: "hippocampus subdivision" EXACT [FMA:74041] synonym: "hippocampus region" RELATED [MA:0002428] subset: non_informative xref: FMA:74041 ! Subdivision of hippocampus xref: MA:0002428 ! hippocampus region is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001954 ! Ammon's horn xref: SCTID:361561007 ! Entire hippocampus (also: UBERON:0001954 'Ammon's horn') [Term] id: UBERON:0003881 name: CA1 field of hippocampus synonym: "CA1" EXACT [] synonym: "CA1 field" EXACT [] synonym: "CA1 field of hippocampus" EXACT [] synonym: "CA1 field of Ammon's horn" EXACT [] synonym: "CA1 field of cornu ammonis" EXACT [] synonym: "hippocampus CA1" EXACT [] synonym: "region 1 of Ammon's horn" EXACT [] synonym: "regio superior of the hippocampus" EXACT [FMA:74042] synonym: "region i of ammon's horn" EXACT [FMA:74042] synonym: "region i of hippocampus proper" EXACT [FMA:74042] synonym: "regio superior" EXACT [NIF_GrossAnatomy:birnlex_1197] synonym: "cornu ammonis 1" EXACT [NIF_GrossAnatomy:birnlex_1197] synonym: "prosubiculum = distal ca1" EXACT [NIF_GrossAnatomy:birnlex_1197] xref: MA:0000950 ! hippocampus CA1 xref: FMA:74042 ! CA1 field xref: EFO:0002454 ! hippocampus CA1 xref: NIF_GrossAnatomy:birnlex_1197 ! CA1 xref: ABA:CA1 ! Field CA1 xref: ncithesaurus:CA1_Field_of_the_Cornu_Ammonis ! CA1 Field of the Cornu Ammonis is_a: UBERON:0003876 ! hippocampal region relationship: spatially_disjoint_from UBERON:0003882 {source="ABA"} ! CA2 field of hippocampus relationship: spatially_disjoint_from UBERON:0003883 {source="ABA"} ! CA3 field of hippocampus synonym: "regio i cornus ammonis" EXACT LATIN [FMA:TA, FMA:74042] synonym: "regio i hippocampi proprii" EXACT LATIN [FMA:TA, FMA:74042] xref: UMLS:C0694598 [Term] id: UBERON:0003882 name: CA2 field of hippocampus synonym: "CA2" EXACT [] synonym: "CA2 field" EXACT [] synonym: "CA2 field of hippocampus" EXACT [] synonym: "CA2 field of cornu ammonis" EXACT [] synonym: "CA2 field of Ammon's horn" EXACT [] synonym: "hippocampus CA2" EXACT [] synonym: "region 2 of Ammon's horn" EXACT [] synonym: "region ii of ammon's horn" EXACT [FMA:74044] synonym: "region ii of hippocampus proper" EXACT [FMA:74044] xref: MA:0000951 ! hippocampus CA2 xref: FMA:74044 ! CA2 field xref: EFO:0002455 ! hippocampus CA2 xref: NIF_GrossAnatomy:birnlex_1362 ! CA2 xref: ABA:CA2 ! Field CA2 xref: ncithesaurus:CA2_Field_of_the_Cornu_Ammonis ! CA2 Field of the Cornu Ammonis is_a: UBERON:0003876 ! hippocampal region relationship: spatially_disjoint_from UBERON:0003881 {source="ABA"} ! CA1 field of hippocampus relationship: spatially_disjoint_from UBERON:0003883 {source="ABA"} ! CA3 field of hippocampus synonym: "regio ii cornus ammonis" EXACT LATIN [FMA:TA, FMA:74044] synonym: "regio ii hippocampi proprii" EXACT LATIN [FMA:TA, FMA:74044] xref: UMLS:C0694599 [Term] id: UBERON:0003883 name: CA3 field of hippocampus def: "Region III of hippocampus proper is a portion of the hippocampal formation. Region CA3 receives input along the mossy fibers from granule cells in the dentate gyrus (DG) and from projection cells in entorhinal cortex along the perforant path. The mossy fiber pathway terminates in stratum lucidum while the perforant path passes through stratum lacunosum and terminates in stratum moleculare. The inputs from the medial septum and diagonal band of Broca terminate in stratum radiatum, along with commisural connections from the contralateral hippocampus. The pyramidal cells in CA3 (of which there are approximately 200,000 in each hemisphere in the rat) send some axons back to the hilus, but the majority project to regions CA2 and CA1 (a pathway called the Schaffer collaterals), in addition to a significant number of connections that terminate within CA3 (called recurrent connections). Both the recurrent connections and the Schaffer collaterals terminate preferentially in the septal or dorsal direction from the originating cells. CA3 also sends a small set of output fibers to the lateral septum. The region is conventionally divided into 3 divisions. CA3a is the part of the cell band which is most distal from the dentate (and closest to CA1). CA3b is the middle part of the band nearest to the fimbria/fornix connection. CA3c is the most proximal to the dentate, inserting into the hilus. The region overall has been considered to be the 'pacemaker' of the hippocampus. In CA3 much of the synchronous bursing activity associated with interictal epileptiform activity appears to be generated. The excitatory collateral interconnectivity appears to be the property of CA3 most responsible for this. CA3, unlike other regions, has pyramidal cell axon collaterals ramifying extensively with local region and making excitatory contacts with neighbors. CA3 has been implicated in a number of working theories on memory and learning hippocampal processes. Oscillatory rhythms (10-30Hz) are cholinergically driven patterns that depend on coupling of interneurons and pyramidal cell axons via gap junctions as well as glutaminergic (excitatory) and GABAergic (inhibitory) synapses. Sharp EEG waves seen here are also implicated in memory consolidation." [Wikipedia:Region_III_of_hippocampus_proper] synonym: "CA3" EXACT [] synonym: "CA3 field" EXACT [] synonym: "CA3 field of hippocampus" EXACT [] synonym: "CA3 field of cornu ammonis" EXACT [] synonym: "CA3 field of Ammon's horn" EXACT [] synonym: "hippocampus CA3" EXACT [] synonym: "region 3 of Ammon's horn" EXACT [] synonym: "region iii of ammon's horn" EXACT [FMA:74045] synonym: "region iii of hippocampus proper" EXACT [FMA:74045] synonym: "regio inferior" EXACT [NIF_GrossAnatomy:birnlex_1204] xref: MA:0000952 ! hippocampus CA3 xref: FMA:74045 ! CA3 field xref: EFO:0002456 ! hippocampus CA3 xref: NIF_GrossAnatomy:birnlex_1204 ! CA3 xref: ABA:CA3 ! Field CA3 xref: ncithesaurus:CA3_Field_of_the_Cornu_Ammonis ! CA3 Field of the Cornu Ammonis is_a: UBERON:0003876 ! hippocampal region relationship: spatially_disjoint_from UBERON:0003881 {source="ABA"} ! CA1 field of hippocampus relationship: spatially_disjoint_from UBERON:0003882 {source="ABA"} ! CA2 field of hippocampus synonym: "regio iii hippocampi proprii" EXACT LATIN [FMA:TA, FMA:74045] synonym: "regio iii cornus ammonis" EXACT LATIN [FMA:TA, FMA:74045] synonym: "regio hippocampi proprii III; regio III cornus ammonis; CA3" RELATED LATIN [Wikipedia:Region_III_of_hippocampus_proper] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/HippocampalRegions.jpg xref: UMLS:C0694600 [Term] id: UBERON:0003884 name: CA4 field of hippocampus comment: consider obsoleting. consider - CA3c, hilus synonym: "CA4" EXACT [] synonym: "CA4 field" EXACT [] synonym: "hippocampus CA4" EXACT [] synonym: "CA4 field of cornu ammonis" EXACT [] synonym: "CA4 field of Ammon's horn" EXACT [] synonym: "region 4 of Ammon's horn" EXACT [] synonym: "region iv of ammon's horn" EXACT [FMA:75741] synonym: "region iv of hippocampus proper" EXACT [FMA:75741] xref: MA:0000953 ! hippocampus CA4 xref: FMA:75741 ! CA4 field xref: EFO:0002457 ! hippocampus CA4 xref: ncithesaurus:CA4_Field_of_the_Cornu_Ammonis ! CA4 Field of the Cornu Ammonis is_a: UBERON:0003876 ! hippocampal region synonym: "regio iv hippocampi proprii" EXACT LATIN [FMA:TA, FMA:75741] synonym: "regio iv cornus ammonis" EXACT LATIN [FMA:TA, FMA:75741] xref: UMLS:C2328406 [Term] id: UBERON:0001955 name: epithelium of respiratory bronchiole def: "An epithelium that is part of a respiratory bronchiole [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "respiratory bronchiole epithelium" EXACT [] synonym: "bronchiolus respiratorius epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchiolus respiratorius epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of bronchiolus respiratorius" EXACT [OBOL:automatic] synonym: "epithelial tissue of respiratory bronchiole" EXACT [OBOL:automatic] synonym: "epithelium of bronchiolus respiratorius" EXACT [OBOL:automatic] synonym: "respiratory bronchiole epithelial tissue" EXACT [OBOL:automatic] xref: FMA:62498 ! Epithelium of respiratory bronchiole xref: MA:0001773 ! respiratory bronchiole epithelium xref: ncithesaurus:Respiratory_Bronchiole_Epithelium ! Respiratory Bronchiole Epithelium is_a: UBERON:0002051 ! epithelium of bronchiole intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002188 ! respiratory bronchiole relationship: part_of UBERON:0002188 ! respiratory bronchiole relationship: has_part CL:0000158 {source="FMA"} ! Clara cell xref: UMLS:C1179179 [Term] id: UBERON:0001956 name: cartilage of bronchus def: "the hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]." [MP:0010988] synonym: "bronchial cartilage" EXACT [] synonym: "bronchus cartilage" EXACT [] synonym: "cartilagines bronchiales" EXACT PLURAL [] synonym: "bronchi cartilage" EXACT [OBOL:automatic] synonym: "bronchial trunk cartilage" EXACT [OBOL:automatic] synonym: "cartilage of bronchi" EXACT [OBOL:automatic] synonym: "cartilage of bronchial trunk" EXACT [OBOL:automatic] synonym: "bronchial cartilage ring" EXACT [MP:0010988] xref: FMA:62649 ! Cartilage of bronchus xref: MA:0001835 ! bronchus cartilage xref: ncithesaurus:Bronchus_Cartilage ! Bronchus Cartilage is_a: UBERON:0001994 {source="MP"} ! hyaline cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0002185 ! bronchus xref: SCTID:278980009 ! Entire bronchial cartilage xref: UMLS:C0225604 [Term] id: UBERON:0001102 name: cartilage of main bronchus def: "A cartilage that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "main bronchial cartilage" EXACT [] synonym: "main bronchus cartilage" EXACT [] synonym: "bronchus principalis cartilage" EXACT [OBOL:automatic] synonym: "cartilage of bronchus principalis" EXACT [OBOL:automatic] synonym: "cartilage of primary bronchus" EXACT [OBOL:automatic] synonym: "cartilage of principal bronchus" EXACT [OBOL:automatic] synonym: "primary bronchus cartilage" EXACT [OBOL:automatic] synonym: "principal bronchus cartilage" EXACT [OBOL:automatic] synonym: "cartilaginous ring of main bronchus" EXACT [EMAPA:19092] xref: FMA:13117 ! Cartilage of main bronchus xref: MA:0001846 ! main bronchus cartilage xref: EMAPA:19092 ! cartilaginous ring of main bronchus is_a: UBERON:0001956 ! cartilage of bronchus intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0002182 ! main bronchus relationship: part_of UBERON:0002182 ! main bronchus [Term] id: UBERON:0001957 name: submucosa of bronchus def: "A submucosa that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "bronchial submucosa" EXACT [] synonym: "bronchus submucosa" EXACT [] synonym: "bronchi submucosa" EXACT [OBOL:automatic] synonym: "bronchial trunk submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bronchi" EXACT [OBOL:automatic] synonym: "submucosa of bronchial trunk" EXACT [OBOL:automatic] xref: FMA:62653 ! Submucosa of bronchus xref: MA:0001837 ! bronchus submucosa xref: ncithesaurus:Bronchus_Submucosa ! Bronchus Submucosa xref: BTO:0002108 ! tela submucosa bronchiorum is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 ! bronchus xref: SCTID:85546005 ! Bronchial submucosa xref: UMLS:C0225601 [Term] id: UBERON:0001958 name: epithelium of terminal bronchiole def: "An epithelium that is part of a terminal bronchiole [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "terminal bronchiole epithelium" EXACT [] synonym: "bronchiolus terminalis epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "epithelial tissue of terminal bronchiole" EXACT [OBOL:automatic] synonym: "epithelium of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "terminal bronchiole epithelial tissue" EXACT [OBOL:automatic] xref: FMA:62794 ! Epithelium of terminal bronchiole xref: MA:0001774 ! terminal bronchiole epithelium xref: ncithesaurus:Terminal_Bronchiole_Epithelium ! Terminal Bronchiole Epithelium is_a: UBERON:0002051 ! epithelium of bronchiole intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002187 ! terminal bronchiole relationship: part_of UBERON:0002187 ! terminal bronchiole relationship: has_part CL:0000158 {source="FMA"} ! Clara cell xref: UMLS:C1179400 [Term] id: UBERON:1000024 name: parenchyma of spleen synonym: "splenic parenchyma" EXACT [FMA:16029] intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002106 ! spleen xref: FMA:16029 ! parenchyma of spleen def: "A parenchyma that is part of a spleen." [OBOL:automatic] [Term] id: UBERON:0005353 name: spleen perifollicular zone def: "the compartment located between the marginal zone and the red pulp harboring scattered B and T lymphocytes[MP]." [MP:0010245] comment: todo - check spleen marginal sinus is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002106 ! spleen [Term] id: UBERON:0010398 name: spleen marginal sinus def: "the border region surrounding the spleen B cell follicles and the periarteriolar lymphoid sheath (PALS) that separates it from the marginal zone that mediates lymphocyte entry into the white pulp from the blood" [MP:MP] comment: Note that there is no consensus in the literature about which compartments constitute the white pulp or the ramifications of the microvasculature. In addition, notable differences exist between humans and rodents. In this ontology, the marginal sinus (which may not exist in human) has been included as part of the white pulp. The perifollicular zone, which is present in human and not rodents, may be the functional equivalent of the marginal sinus in rodents.[MP:0002363] synonym: "splenic marginal sinus" EXACT [MP:0002363] is_a: UBERON:0001959 ! white pulp of spleen xref: MA:0000754 ! spleen marginal sinus xref: ncithesaurus:Splenic_Marginal_Sinus ! splenic marginal sinus xref: UMLS:C1710157 [Term] id: UBERON:0001251 name: marginal zone of spleen def: "region at the interface between the non-lymphoid red pulp and the lymphoid white-pulp of the spleen." [Wikipedia:Marginal_zone] comment: WP says - (Some sources consider it to be the part of red pulp which borders on the white pulp, while other sources consider it to be neither red pulp nor white pulp.) - we use the adjacency relation here so it overlaps neither. FMA considers this an anatomical line. Not to be confused with: Marginal zone of spleen (e.g. AAO:0010448 marginal zone) synonym: "junctional zone of spleen" EXACT [] synonym: "marginal zone" BROAD [Wikipedia:Marginal_zone] synonym: "spleen marginal zone" EXACT [] xref: FMA:15852 ! Marginal zone of spleen xref: MA:0000755 ! spleen marginal zone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/15/Gray1191.png/200px-Gray1191.png is_a: UBERON:0000466 ! immaterial anatomical entity disjoint_from: UBERON:0004879 ! marginal zone of embryo relationship: part_of UBERON:0002106 ! spleen relationship: adjacent_to UBERON:0001250 ! red pulp of spleen relationship: adjacent_to UBERON:0001959 ! white pulp of spleen xref: ncithesaurus:Marginal_Zone ! Marginal Zone xref: http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1191.png xref: UMLS:C1711368 [Term] id: UBERON:1000023 ! spleen pulp name: spleen pulp synonym: "malpighian corpuscles" EXACT [FMA:15845] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002106 {source="MA"} ! spleen relationship: part_of UBERON:1000024 {source="FMA"} ! parenchyma of spleen synonym: "splenic pulp" EXACT [] synonym: "pulp of spleen" EXACT [] xref: MA:0002487 ! spleen pulp xref: FMA:15845 ! splenic pulp xref: SCTID:13515001 ! Splenic pulp xref: ncithesaurus:Splenic_Pulp ! Splenic Pulp xref: UMLS:C0229691 [Term] id: UBERON:0001959 name: white pulp of spleen def: "The white pulp contains T cells, B cells and accessory cells. The function of the white pulp is to mount an immunological response to antigens within the blood. The white pulp is present in the form of a periarteriolar lymphoid sheath. This sheath contains B cell follicles and T cells. At the edge of the T zone is a region known as the marginal zone where larger lymphocytes and antigen presenting dendritic cells are located." [Wikipedia:White_pulp] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "splenic white pulp" EXACT [] synonym: "spleen white pulp" EXACT [] synonym: "white pulp" EXACT [] xref: FMA:62805 ! White pulp of spleen xref: MA:0000762 ! spleen white pulp xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/15/Gray1191.png/200px-Gray1191.png xref: ncithesaurus:Splenic_White_Pulp ! Splenic White Pulp is_a: UBERON:1000023 ! spleen pulp relationship: composed_primarily_of CL:0000542 ! lymphocyte synonym: "pulpa alba" EXACT LATIN [FMA:TA, FMA:62805] synonym: "noduli lymphoidei splenici" RELATED LATIN [Wikipedia:White_pulp] xref: http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1191.png xref: UMLS:C0229686 [Term] id: UBERON:0001250 name: red pulp of spleen def: "Red pulp of the spleen is composed of connective tissue known as the cords of Billroth and many splenic sinuses that are engorged with blood, giving it a red color. Its primary function is to filter the blood of antigens, microorganisms, and defective or worn-out red blood cells. The spleen is made of red pulp and white pulp, separated by the marginal zone; 76-79% of a normal spleen is red pulp. Unlike white pulp, which mainly contains lymphocytes such as T cells, red pulp is made up of several different types of blood cells, including platelets, granulocytes, red blood cells, and plasma." [Wikipedia:Red_pulp] subset: uberon_slim synonym: "red pulp" EXACT [] synonym: "spleen red pulp" EXACT [] synonym: "splenic red pulp" EXACT [] xref: FMA:15844 ! Red pulp of spleen xref: MA:0000756 ! spleen red pulp xref: ncithesaurus:Splenic_Red_Pulp ! Splenic Red Pulp xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/15/Gray1191.png/200px-Gray1191.png is_a: UBERON:1000023 ! spleen pulp relationship: composed_primarily_of CL:0000542 ! lymphocyte relationship: present_in_taxon NCBITaxon:7955 {source="doi:10.1177/0192623311409597"} ! Danio rerio synonym: "pulpa rubra" EXACT LATIN [FMA:TA, FMA:15844] xref: SCTID:27579002 ! Splenic red pulp synonym: "pulpa splenica" RELATED LATIN [Wikipedia:Red_pulp] xref: http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1191.png xref: UMLS:C0229687 [Term] id: UBERON:0012069 name: epithelium-associated lymphoid tissue is_a: UBERON:0001744 {source="FMA"} ! lymphoid tissue xref: FMA:62811 ! epithelium-associated lymphoid tissue [Term] id: UBERON:0001961 name: mucosa-associated lymphoid tissue def: "diffuse system of small concentrations of lymphoid tissue found in various sites of the body such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin[WP]. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes[GO]." [Wikipedia:Mucosa-associated_lymphoid_tissue] comment: Editor notes: todo - add part relationships to specific layers subset: uberon_slim synonym: "epithelio-lymphoid tissue" EXACT [FMA:62819] synonym: "MALT" EXACT [] synonym: "mucosal-associated lymphatic tissue" EXACT [GO:0048537] synonym: "mucosal-associated lymphoid tissue" EXACT [GO:0048537] synonym: "mucosa-associated lymphoid tissue" EXACT [GO:0048537] synonym: "mucosa associated lymphatic tissue" EXACT [] synonym: "mucosa associated lymphoid tissue" EXACT [] xref: FMA:62819 ! Mucosa-associated lymphoid tissue xref: MA:0000140 ! mucosa associated lymphoid tissue xref: ncithesaurus:Mucosa-Associated_Lymphoid_Tissue ! Mucosa-Associated Lymphoid Tissue is_a: UBERON:0012069 {source="FMA"} ! epithelium-associated lymphoid tissue relationship: overlaps UBERON:0000344 ! mucosa relationship: site_of GO:0046649 ! lymphocyte activation xref: UMLS:C0599921 [Term] id: UBERON:0001962 name: gut-associated lymphoid tissue def: "Mucosa-associated lymphoid tissue in digestive tract. includes Peyer's patches, appendix, and solitary lymph nodules[GO]." [Wikipedia:Gut-associated_lymphoid_tissue] comment: Editor notes: phylogenetic relationships to be added. Taxon notes: guts of jawless fish contains cells with lymphocyte-like morphology (Mayer 2002). subset: uberon_slim synonym: "GALT" RELATED [] synonym: "gut associated lymphoid tissue" EXACT [] xref: FMA:62820 ! Gut-associated lymphoid tissue xref: MA:0000136 ! gut associated lymphoid tissue xref: ncithesaurus:Gut_Associated_Lymphoid_Tissue ! Gut-Associated Lymphoid Tissue intersection_of: UBERON:0001961 ! mucosa-associated lymphoid tissue intersection_of: part_of UBERON:0001555 ! digestive tract xref: UMLS:C0596638 [Term] id: UBERON:0001963 name: bronchial-associated lymphoid tissue def: "A diffuse collection of lymphpoid cells that participate in airway immune responses" [ISBN10:0123813611] comment: Lymphoid tissue associated with airways in mice has functional similarities to human BALT[ISBN10:0123813611] Notes: FMA classifies this as organized, not diffuse synonym: "BALT" RELATED [] synonym: "bronchus associated lymphoid tissue" EXACT [] xref: FMA:62821 ! Bronchial-associated lymphoid tissue xref: MA:0000135 ! bronchus associated lymphoid tissue xref: ncithesaurus:Bronchus-Associated_Lymphoid_Tissue ! Bronchus-Associated Lymphoid Tissue intersection_of: UBERON:0001961 ! mucosa-associated lymphoid tissue intersection_of: part_of UBERON:0002185 ! bronchus relationship: overlaps UBERON:0001957 {source="ISBN10:0123813611"} ! submucosa of bronchus xref: UMLS:C1179418 [Term] id: UBERON:0012330 name: nasal-associated lymphoid tissue synonym: "NALT" RELATED [Wikipedia:Mucosa-associated_lymphoid_tissue#Categorisation] synonym: "naso-pharyngeal lymphoid tissue" EXACT [FMA:79771] xref: ncithesaurus:Nasal-Associated_Lymphoid_Tissue ! nasal-associated lymphoid tissue xref: FMA:79771 ! naso-pharyngeal lymphoid tissue intersection_of: UBERON:0001961 ! mucosa-associated lymphoid tissue intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: overlaps UBERON:0005022 ! mucosa of nasopharynx xref: UMLS:C2698431 [Term] id: UBERON:0013478 name: cecal tonsil def: "A thickened round patch of lymphoid tissue located at the ileocecal junction adjacent to the sacculus rotundus." [ISBN:0824754077] comment: In avians the polycryptic cecal tissue is similar to the mammalian palatine tonsil synonym: "caecal tonsil" EXACT [] synonym: "cecal GALT" RELATED [] intersection_of: UBERON:0001961 ! mucosa-associated lymphoid tissue intersection_of: part_of UBERON:0001153 ! caecum relationship: part_of UBERON:0000314 ! cecum mucosa relationship: present_in_taxon NCBITaxon:8782 ! Aves xref: SCTID:14239003 ! Cecal tonsil [Term] id: UBERON:0001964 name: least splanchnic nerve def: "Thoracic nerve that nerve travels into the abdomen, where its fibers synapse in the renal ganglia." [Wikipedia:Thoracic_splanchnic_nerves#cite_note-4] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "thoracic splanchnic nerve" RELATED [] synonym: "least thoracic splanchnic nerve" EXACT [FMA:6283] synonym: "lowest splanchnic nerve" EXACT [FMA:6283] synonym: "ramus renalis nervus splanchnici minoris" EXACT [FMA:TA] synonym: "renal branch of lesser splanchnic nerve" EXACT [FMA:6283] synonym: "renal nerve" EXACT [FMA:6283] synonym: "nervus splanchnicus imus" EXACT LATIN [FMA:TA, FMA:6283] synonym: "ramus renalis nervus splanchnici minoris" EXACT LATIN [FMA:TA, FMA:6283] xref: FMA:6283 ! Least splanchnic nerve xref: MA:0002635 ! renal nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Gray838.png/200px-Gray838.png xref: EMAPA:29691 ! renal nerve is_a: UBERON:0003715 ! splanchnic nerve relationship: part_of UBERON:0002113 {source="MA"} ! kidney xref: SCTID:280506004 ! Entire least splanchnic nerve subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png [Term] id: UBERON:0001965 name: substantia nigra pars compacta def: "Regional part of substantia nigra consisting of a densely packed region of cells, more or less dorsal to the pars reticulata, but extending into the pars reticulata in some species. The dominant neurotransmitter used by pars compacta neurons is dopamine. Pars compacta neurons are pigmented in many species (MM)[NIF]." [NIF_GrossAnatomy:birnlex_990, Wikipedia:Substantia_nigra_pars_compacta] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "compact part of substantia nigra" EXACT [] synonym: "pars compacta" EXACT [] synonym: "SNpc" EXACT [] synonym: "substantia nigra, compact part" EXACT [] synonym: "substantia nigra compact part" EXACT [NIF_GrossAnatomy:birnlex_990] synonym: "substantia nigra compacta" EXACT [NIF_GrossAnatomy:birnlex_990] xref: FMA:62907 ! Substantia nigra pars compacta xref: MA:0001064 ! substantia nigra pars compacta xref: NIF_GrossAnatomy:birnlex_990 ! Substantia nigra pars compacta xref: BTO:0003749 ! pars compacta xref: ABA:SNc ! Substantia nigra, compact part xref: BM:MB-SNc ! pars compacta of substantia nigra is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002038 ! substantia nigra relationship: spatially_disjoint_from UBERON:0002142 {source="ABA"} ! pedunculopontine tegmental nucleus relationship: spatially_disjoint_from UBERON:0007412 {source="ABA"} ! midbrain raphe nuclei synonym: "pars compacta substantiae nigrae" EXACT LATIN [FMA:TA, FMA:62907] xref: ncithesaurus:Pars_Compacta ! pars compacta xref: UMLS:C0175412 [Term] id: UBERON:0001966 ! substantia nigra pars reticulata name: substantia nigra pars reticulata def: "Regional part of substantia nigra consisting of loosely packed cells, generally located ventral and lateral to the pars compacta. Many cells in this region use GABA as a neurotransmitter (MM)[NLex]." [Wikipedia:Pars_reticulata, Neurolex:Substantia_nigra_pars_reticulata] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "pars reticulata" EXACT [] synonym: "reticular part of substantia nigra" EXACT [] synonym: "substantia nigra, reticular part" EXACT [] xref: FMA:62908 ! Substantia nigra pars reticulata xref: MA:0001066 ! substantia nigra pars reticulata xref: NIF_GrossAnatomy:birnlex_968 ! Substantia nigra pars reticulata xref: BTO:0003750 ! pars reticulata xref: ABA:SNr ! Substantia nigra, reticular part xref: BM:MB-SNr ! pars reticulata of substantia nigra is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002038 ! substantia nigra relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus synonym: "pars reticularis substantiae nigrae" EXACT LATIN [FMA:TA, FMA:62908] [Term] id: UBERON:0001967 name: reticular lamina def: "a thin extracellular layer that sometimes lies below the basal lamina, is composed chiefly of collagenous fibers, and serves to anchor the basal lamina to underlying connective tissue." [http://mw1.merriam-webster.com/medical/reticular%20lamina, Wikipedia:Reticular_lamina] comment: todo - use GO? subset: uberon_slim synonym: "fibroreticular lamina" EXACT [] synonym: "lamina fibroreticularis" EXACT [] synonym: "reticular membrane" RELATED [] xref: FMA:62924 ! Reticular lamina is_a: UBERON:0005764 {source="FMA"} ! acellular membrane relationship: part_of UBERON:0005769 {source="FMA"} ! basement membrane [Term] id: UBERON:0007825 name: reticular membrane of spiral organ synonym: "reticular lamina" BROAD [MA:0001194] synonym: "reticular lamina of spiral organ" EXACT [OBOL:automatic] synonym: "reticular lamina of spiral organ of cochlea" EXACT [OBOL:automatic] xref: FMA:77849 ! reticular membrane of spiral organ xref: MA:0001194 ! reticular lamina is_a: UBERON:0001967 {source="Obol"} ! reticular lamina relationship: part_of UBERON:0002227 {source="MA"} ! spiral organ of cochlea [Term] id: UBERON:0001968 name: semen def: "Body substance which consists of spermatozoa and seminal plasma.[FMA]" [Wikipedia:Semen, FMA:FMA] comment: Taxon notes: Note that in this ontology, semen is defined as the sum of sperm and seminal fluid, where seminal fluid is defined a taxonomically generic way (see comments for UBERON:0006530). subset: uberon_slim xref: BTO:0001230 xref: FMA:62966 ! Semen xref: GAID:1169 ! semen xref: MA:0002522 ! semen xref: OpenCyc:Mx4rvgC-zpwpEbGdrcN5Y29ycA xref: ncithesaurus:Semen ! Semen xref: OpenCyc:Mx4rvgC-zpwpEbGdrcN5Y29ycA ! semen xref: MESH:A12.200.732 ! semen xref: ncithesaurus:Male_Genital_System_Fluid_or_Secretion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/40/Human_semen_in_petri_dish2.jpg/180px-Human_semen_in_petri_dish2.jpg is_a: UBERON:0000463 ! portion of organism substance relationship: output_of GO:0042713 ! sperm ejaculation relationship: has_part UBERON:0006530 ! seminal fluid relationship: has_part CL:0000019 ! sperm property_value: has_relational_adjective "seminal" xsd:string xref: UMLS:C1518159 xref: UMLS:C2756969 [Term] id: UBERON:0006530 ! seminal fluid name: seminal fluid def: "The fluid portion of the semen, in which the spermatozoa are suspended[BTO]." [BTO:0001232] comment: Usage notes: we follow FMA and make this class a generic superclass of the secretions of different glands (prostate, bulbo-urethreal, seminal vesicle). MA (and ncit) follows a mixture model, where these secretions are part of the seminal fluid // Taxon notes: This term covers a variety of species. Example: In D. melanogaster, seminal fluid proteins affect female receptivity, ovulation, oogenesis, sperm storage, sperm competition and mating plug formation [doi:10.1046/j.1365-2540.2001.00961.x]. Note that ths intology contains a number of subtypes of seminal fluid, defined according to glands (which are more taxonomically restricted) synonym: "seminal fluid" RELATED [BTO:0001232] synonym: "seminal plasma" EXACT [BTO:0001232] synonym: "male genital fluid" RELATED [] synonym: "male genital secretion" RELATED [] xref: MA:0002523 ! seminal fluid xref: FMA:62967 ! Seminal fluid xref: MAT:0000057 ! seminal fluid xref: MIAA:0000057 ! seminal fluid xref: BTO:0001232 ! seminal plasma is_a: UBERON:0000456 ! bodily secretion relationship: part_of UBERON:0001968 ! semen [Term] id: UBERON:0004796 alt_id: UBERON:0010142 name: prostate gland secretion def: "A secretion of the prostate this is slightly alkaline fluid, milky or white in appearance. Usually constitutes 20–30% of the volume of the semen along with spermatozoa and seminal vesicle fluid" [Wikipedia:Prostate#Secretions] comment: Taxon notes: Prostatic secretions vary among species. They are generally composed of simple sugars and are often slightly alkaline. synonym: "prostate secretion" EXACT [OBOL:automatic] synonym: "secretion of prostate" EXACT [OBOL:automatic] synonym: "secretion of prostate gland" EXACT [OBOL:automatic] synonym: "prostatic fluid" EXACT [FMA:66884] xref: MA:0002525 ! prostate gland secretion xref: FMA:66884 ! prostatic fluid is_a: UBERON:0006530 {source="FMA"} ! seminal fluid intersection_of: UBERON:0000456 ! bodily secretion intersection_of: secreted_by UBERON:0002367 ! prostate gland xref: ncithesaurus:Prostate_Gland_Secretion ! Prostate Gland Secretion xref: UMLS:C1709733 [Term] id: UBERON:0010143 ! seminal vesicle fluid name: seminal vesicle fluid comment: AO notes: in ncit, seminal fluid is a subtype of seminal vesicle secretion synonym: "seminal vesicle secretion" EXACT [FMA:62969] synonym: "secretion of seminal vesicle" EXACT [FMA:62969] synonym: "vesicular fluid" BROAD [] synonym: "seminal fluid" RELATED INCONSISTENT [] is_a: UBERON:0006530 {source="FMA"} ! seminal fluid intersection_of: UBERON:0000456 ! bodily secretion intersection_of: secreted_by UBERON:0000998 ! seminal vesicle xref: FMA:62969 ! secretion of seminal vesicle xref: MA:0002526 ! seminal vesicle secretion xref: ncithesaurus:Seminal_Vesicle_Secretion xref: ncithesaurus:Seminal_Fluid ! Seminal Fluid def: "A bodily secretion that secreted_by a seminal vesicle." [OBOL:automatic] xref: UMLS:C0036614 xref: UMLS:C0227987 [Term] id: UBERON:0004691 name: bulbourethral gland secretion def: "A clear, viscous secretion that helps to lubricate the urethra for spermatozoa to pass through, neutralizing traces of acidic urine in the urethra,[2] and helps flush out any residual urine or foreign matter. It is possible for this fluid to pick up sperm, remaining in the urethral bulb from previous ejaculations, and carry them out prior to the next ejaculation[WP]." [Wikipedia:Bulbourethral_gland#Function] synonym: "bulbo-urethral gland secretion" EXACT [FMA:62968] synonym: "secretion of bulbo-urethral gland" EXACT [FMA:62968] synonym: "pre-ejaculate" EXACT [Wikipedia:Pre-ejaculate] xref: FMA:62968 ! secretion of bulbo-urethral gland xref: MA:0002524 ! bulbourethral gland secretion is_a: UBERON:0006530 {source="FMA"} ! seminal fluid intersection_of: UBERON:0000456 ! bodily secretion intersection_of: secreted_by UBERON:0002366 ! bulbo-urethral gland xref: ncithesaurus:Bulbourethral_Gland_Secretion ! Bulbourethral Gland Secretion xref: UMLS:C1707061 [Term] id: UBERON:0010148 name: mating plug def: "A gelatinous secretion used in the mating of some species. It is deposited by a male into a female genital tract and later hardens into a plug or glues the tract together." [Wikipedia:Mating_plug] synonym: "copulatory plug" EXACT [SPD:0000547] synonym: "copulation plug" EXACT [Wikipedia:Mating_plug] synonym: "sperm plug" EXACT [Wikipedia:Mating_plug] synonym: "vaginal plug" EXACT [Wikipedia:Mating_plug] synonym: "sement" RELATED [Wikipedia:Mating_plug] synonym: "sphragis" RELATED [Wikipedia:Mating_plug] is_a: UBERON:0000463 ! portion of organism substance relationship: has_function_in GO:0046692 ! sperm competition relationship: present_in_taxon NCBITaxon:10088 ! Mus relationship: present_in_taxon NCBITaxon:6656 ! Arthropoda relationship: present_in_taxon NCBITaxon:9397 ! Chiroptera relationship: present_in_taxon NCBITaxon:9443 ! Primates xref: SPD:0000547 ! mating plug [Term] id: UBERON:0001969 name: blood plasma def: "Body substance in liquid state contained in the lumen of arterial and venous trees, blood capillary and the cardiac chambers; constitutes the liquid phase of blood.[FMA]" [Wikipedia:Blood_plasma, FMA:FMA] subset: uberon_slim synonym: "plasma" EXACT [] synonym: "portion of blood plasma" EXACT [] synonym: "portion of plasma" EXACT [] xref: BTO:0000131 xref: FMA:62970 ! Portion of plasma xref: GAID:1178 ! plasma xref: MA:0002501 ! plasma xref: MAT:0000052 ! blood plasma xref: MIAA:0000052 ! blood plasma xref: OpenCyc:Mx4rEg4ZYrIbEduAAAAOpmP6tw xref: ncithesaurus:Plasma ! Plasma xref: EFO:0001905 ! blood plasma xref: OpenCyc:Mx4rEg4ZYrIbEduAAAAOpmP6tw ! blood plasma xref: MESH:A12.207.152.693 ! plasma is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0000178 ! blood xref: UMLS:C0032105 [Term] id: UBERON:0007803 ! preen oil name: preen oil comment: The uropygial gland is involved in maintaining feather condition and secretions spread by preening. It serves a waterproofing function. The secretions contain a pro-vitamin D, converted by UV light to active vitamin D. The secretions are also believed to suppress the growth of micro-organisms, serving an anti-bacterial function. [http://en.wikivet.net] is_a: UBERON:0000463 ! portion of organism substance synonym: "preen gland secretion" RELATED [] synonym: "uropygial gland secretion" RELATED [] relationship: has_function_in GO:0007625 ! grooming behavior relationship: has_function_in NBO:0000451 ! personal grooming relationship: secreted_by UBERON:0007802 ! uropygial gland [Term] id: UBERON:0001970 name: bile def: "a bitter-tasting, dark green to yellowish brown fluid, produced by the liver of most vertebrates, that aids the process of digestion of lipids in the small intestine. In many species, bile is stored in the gallbladder and upon eating is discharged into the duodenum. Bile is a composition of the following materials: water (85%), bile salts (10%), mucus and pigments (3%), fats (1%), inorganic salts (0.7%) and cholesterol (0.3%)[WP]." [Wikipedia:Bile] subset: uberon_slim synonym: "fel" RELATED [BTO:0000121] synonym: "gall" RELATED [BTO:0000121] xref: BTO:0000121 xref: ENVO:02000023 xref: FMA:62971 ! Bile xref: GAID:1157 ! bile xref: galen:Bile xref: MA:0002513 ! bile xref: ncithesaurus:Bile ! Bile xref: MESH:A12.200.087 ! bile is_a: UBERON:0000463 ! portion of organism substance is_a: UBERON:0000456 ! bodily secretion xref: UMLS:C0005388 [Term] id: UBERON:0001971 name: gastric juice def: "." [Wikipedia:Gastric_juice] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "stomach secretion" EXACT [] synonym: "succus gastricus" RELATED [BTO:0000501] xref: BTO:0000501 xref: FMA:62972 ! Gastric juice xref: GAID:1160 ! gastric juice xref: galen:GastricJuice xref: MA:0002519 ! stomach secretion xref: MESH:A12.200.307 ! gastric juice xref: ncithesaurus:Gastric_Secretion ! gastric secretion is_a: UBERON:0000456 ! bodily secretion xref: UMLS:C0017133 [Term] id: UBERON:0001972 name: submucosa of esophagus def: "A submucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "tela submucosa esophagi" EXACT LATIN [BTO:0002109] synonym: "tela submucosa of esophagus" EXACT [] synonym: "esophageal submucosa" EXACT [] synonym: "esophageal submucosa" EXACT [] synonym: "esophagus submucosa" EXACT [] synonym: "submucosa of esophagus" EXACT [] synonym: "gullet submucosa" EXACT [OBOL:automatic] synonym: "oesophagus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of gullet" EXACT [OBOL:automatic] synonym: "submucosa of oesophagus" EXACT [OBOL:automatic] xref: FMA:62997 ! Submucosa of esophagus xref: MA:0002724 ! esophagus submucosa xref: BTO:0002109 ! tela submucosa esophagi is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 ! wall of esophagus synonym: "tela submucosa oesophageae" EXACT LATIN [FMA:TA, FMA:62997] xref: SCTID:362128009 ! Entire esophageal submucosa [Term] id: UBERON:0001973 name: substance of tooth def: "Body substance in solid state produced by odontoblasts, amyloblasts or cementoblasts.[FMA]" [FMA:63001] comment: note the asserted dual parentage. This is deliberate, pending better definitions of the distinction between substance and tissue subset: uberon_slim synonym: "tooth substance" EXACT [] synonym: "portion of substance of tooth" EXACT [FMA:63001] xref: FMA:63001 ! Portion of substance of tooth xref: MA:0002540 ! tooth substance is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0001091 ! tooth [Term] id: UBERON:0001974 name: lamina propria of esophagus def: "A lamina propria that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "esophagus lamina propria" EXACT [] synonym: "lamina propria mucosae of esophagus" EXACT [] synonym: "oesophagus lamina propria" RELATED [] synonym: "esophagus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "esophagus lamina propria mucosae" EXACT [OBOL:automatic] synonym: "gullet lamina propria" EXACT [OBOL:automatic] synonym: "gullet lamina propria mucosa" EXACT [OBOL:automatic] synonym: "gullet lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of esophagus" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of gullet" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of gullet" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of oesophagus" EXACT [OBOL:automatic] synonym: "lamina propria of gullet" EXACT [OBOL:automatic] synonym: "lamina propria of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "oesophagus lamina propria mucosae" EXACT [OBOL:automatic] xref: FMA:63050 ! Lamina propria of esophagus xref: MA:0001568 ! esophagus lamina propria xref: EMAPA:26987 ! lamina propria of mucosa of oesophagus of foregut xref: EMAPA:27003 ! lamina propria of mucosa of oesophagus of gut xref: ncithesaurus:Esophageal_Lamina_Propria ! Esophageal Lamina Propria is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0002469 {source="FMA"} ! esophagus mucosa xref: UMLS:C1707949 [Term] id: UBERON:0001975 name: serosa of esophagus def: "A serous membrane that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "esophagus serosa" EXACT [] synonym: "oesophagus serosa" RELATED [] synonym: "serosa of abdominal part of esophagus" EXACT [] synonym: "serosa of oesophagus" EXACT [] synonym: "serous coat of oesophagus" EXACT [] synonym: "esophagus serous membrane" EXACT [OBOL:automatic] synonym: "gullet serosa" EXACT [OBOL:automatic] synonym: "gullet serous membrane" EXACT [OBOL:automatic] synonym: "oesophagus serous membrane" EXACT [OBOL:automatic] synonym: "serosa of gullet" EXACT [OBOL:automatic] synonym: "serous membrane of esophagus" EXACT [OBOL:automatic] synonym: "serous membrane of gullet" EXACT [OBOL:automatic] synonym: "serous membrane of oesophagus" EXACT [OBOL:automatic] xref: FMA:63057 ! Serosa of esophagus xref: MA:0001571 ! esophagus serosa is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 ! wall of esophagus synonym: "tunica serosa oesophageae" EXACT LATIN [FMA:TA, FMA:63057] [Term] id: UBERON:0001976 name: epithelium of esophagus comment: todo check epithelium types: in FMA: Nonkeratinizing stratified squamous epithelium; mouse has basal and squamous subtypes; in ZFA it is columnar subset: uberon_slim subset: vertebrate_core synonym: "esophageal epithelium" EXACT [] synonym: "esophagus epithelium" EXACT [] synonym: "oesophagus epithelium" RELATED [] synonym: "epithelial tissue of esophagus" EXACT [OBOL:automatic] synonym: "epithelial tissue of gullet" EXACT [OBOL:automatic] synonym: "epithelial tissue of oesophagus" EXACT [OBOL:automatic] synonym: "epithelium of gullet" EXACT [OBOL:automatic] synonym: "epithelium of oesophagus" EXACT [OBOL:automatic] synonym: "esophagus epithelial tissue" EXACT [OBOL:automatic] synonym: "gullet epithelial tissue" EXACT [OBOL:automatic] synonym: "gullet epithelium" EXACT [OBOL:automatic] synonym: "oesophagus epithelial tissue" EXACT [OBOL:automatic] xref: FMA:63063 ! Epithelium of esophagus xref: MA:0001565 ! esophagus epithelium xref: TAO:0001499 ! esophageal epithelium xref: ZFA:0001499 ! esophageal epithelium xref: ncithesaurus:Esophageal_Epithelium ! Esophageal Epithelium xref: BTO:0001578 ! esophageal epithelium xref: EHDAA2:0001287 ! oesophagus epithelium xref: EMAPA:16835 ! epithelium of oesophagus of foregut xref: EFO:0003041 ! esophageal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0002469 {source="FMA"} ! esophagus mucosa property_value: external_definition "Simple columnar epithelium that lines the esophagus. Chen et al, 2007.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001499", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "An epithelium that is part of a esophagus." [OBOL:automatic] xref: UMLS:C1179544 [Term] id: UBERON:0006920 name: esophagus squamous epithelium comment: MA introduces basal and squamous subtypes of esophagus epithelium; consider adding the FMA class 'epithelium of esophagus' here, because it is classified as squamous. BTO also has a singleton subclass synonym: "squamous oesophageal epithelium" RELATED [MA:0001567] synonym: "esophageal squamous epithelium" RELATED [OBOL:automatic] synonym: "squamous epithelium of esophagus" RELATED [OBOL:automatic] xref: MA:0001567 ! esophagus squamous epithelium xref: BTO:0003635 ! esophageal squamous epithelium xref: ncithesaurus:Esophageal_Squamous_Epithelium ! Esophageal Squamous Epithelium intersection_of: UBERON:0006914 ! squamous epithelium intersection_of: part_of UBERON:0001043 ! esophagus def: "A squamous epithelium that is part of a esophagus." [OBOL:automatic] xref: UMLS:C1707950 [Term] id: UBERON:0001977 name: serum def: "Body substance derived from plasma by the elimination of fibrinogen.[FMA]" [Wikipedia:Serum, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "blood serum" EXACT [] xref: BTO:0000133 xref: BTO:0001239 xref: FMA:63083 ! Serum xref: MA:0002502 ! serum xref: ncithesaurus:Serum ! Serum xref: EHDAA2:0004728 ! serum is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0001969 ! blood plasma xref: UMLS:C0229671 [Term] id: UBERON:0001978 name: parenchyma of pancreas comment: This class was created automatically from a combination of ontologies synonym: "pancreas parenchyma" EXACT [] synonym: "pancreatic parenchyma" EXACT [] xref: FMA:63120 ! Parenchyma of pancreas xref: VHOG:0001430 ! pancreas parenchyma xref: MA:0000724 ! pancreas parenchyma is_a: UBERON:0000353 ! parenchyma relationship: part_of UBERON:0001264 ! pancreas xref: SCTID:371401008 ! Structure of parenchyma of pancreas [Term] id: UBERON:0001979 name: venule def: "Subdivision of venous tree (organ) which is directly continuous with the capillary vessel." [Wikipedia:Venule] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core xref: FMA:63130 ! Venule xref: MA:0000071 ! venule xref: ncithesaurus:Venule ! Venule xref: BTO:0002626 ! venule xref: ZFA:0005315 ! venule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Illu_capillary.jpg/200px-Illu_capillary.jpg xref: MESH:A07.231.432.952 ! venule is_a: UBERON:0003920 ! venous blood vessel relationship: part_of UBERON:0001009 ! circulatory system xref: SCTID:341687009 ! Entire venule xref: TAO:0005315 ! venule synonym: "venula" RELATED LATIN [Wikipedia:Venule] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg xref: VHOG:0001765 ! venule property_value: external_definition "Multi-tissue structure part of the blood vasculature formed by the anastomosis of capillaries. Venules carry blood toward the heart.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005315", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0042520 [Term] id: UBERON:0001980 name: arteriole def: "the smallest division of the artery located between the muscular arteries and the capillaries[GO]. Subdivision of arterial tree (organ) which is directly continuous with capillary vessel[FMA]." [Wikipedia:Arteriole, FMA:63182, GO:0014830] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core xref: FMA:63182 ! Arteriole xref: MA:0000063 ! arteriole xref: ncithesaurus:Arteriole ! Arteriole xref: BTO:0001997 ! arteriole xref: ZFA:0005255 ! arteriole xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Illu_capillary.jpg/200px-Illu_capillary.jpg xref: MESH:A07.231.114.060 ! arteriole is_a: UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001637 ! artery xref: AAO:0010253 ! arteriole xref: SCTID:337724002 ! Entire arteriole xref: TAO:0002138 ! arteriole synonym: "arteriola" RELATED LATIN [Wikipedia:Arteriole] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg property_value: external_definition "Small, terminal branch of an artery which generally connects to capillaries.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010253", date_retrieved="2012-06-20", source="AAO:BJB"} xref: VHOG:0001763 ! arteriole property_value: external_definition "Multi-tissue structure part of the blood vasculature, feeds into capillaries. Arterioles carry blood away from the heart.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002138", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0003847 [Term] id: UBERON:0004536 ! lymph vasculature name: lymph vasculature def: "A network of blunt ended vessels lacking direct connection to the blood vascular system. These vessels collect and drain fluids and macromolecules from interstitial spaces throughout the animal. They derive from a subpopulation of endothelial cells and have walls that are much thinner than the blood carrying vessels. Lymphatic vessels are usually classified as either superficial or deep." [ZFA:0005105] subset: vertebrate_core synonym: "set of lymphatic vessels" EXACT [] synonym: "lymphatic vasculature" EXACT [] synonym: "lymphatic vessel network" EXACT [] synonym: "lymphatic trunks and ducts" EXACT [FMA:63815] synonym: "lymphatic vessels set" EXACT [FMA:63815] xref: FMA:63815 ! Set of lymphatic vessels xref: ZFA:0005105 ! lymph vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: has_part UBERON:0002391 ! lymph relationship: part_of UBERON:0002465 ! lymphoid system synonym: "trunci et ductus lymphatici" EXACT LATIN [FMA:TA, FMA:63815] xref: TAO:0005105 ! lymph vessel (also: UBERON:0001473 'lymphatic vessel') property_value: external_definition "A network of blunt ended vessels lacking direct connection to the blood vascular system. These vessels collect and drain fluids and macromolecules from interstitial spaces throughout the animal. They derive from a subpopulation of endothelial cells and have walls that are much thinner than the blood carrying vessels. Lymphatic vessels are usually classified as either superficial or deep.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005105", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0001473 name: lymphatic vessel def: "A vessel that contains or conveys lymph, that originates as an interfibrillar or intercellular cleft or space in a tissue or organ, and that if small has no distinct walls or walls composed only of endothelial cells and if large resembles a vein in structure[BTO]." [BTO:0000752, Wikipedia:Lymphatic_vessel] subset: uberon_slim subset: vertebrate_core synonym: "lymph vessel" EXACT [] xref: BTO:0000752 xref: EFO:0000873 ! lymph vessel xref: FMA:30315 ! Lymphatic vessel xref: VHOG:0001249 ! lymph vessel xref: MA:0000138 ! lymphatic vessel xref: MAT:0000443 ! lymph vessel xref: TAO:0005105 ! lymph vessel (also: UBERON:0004536 'lymph vasculature') xref: XAO:0000375 ! lymph vessel xref: ncithesaurus:Lymphatic_Vessel ! Lymphatic Vessel xref: OpenCyc:Mx4rwA1fYZwpEbGdrcN5Y29ycA ! lymph vessel xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/44/Illu_lymph_capillary.jpg/200px-Illu_lymph_capillary.jpg is_a: UBERON:0000055 ! vessel disjoint_from: UBERON:0001981 ! blood vessel relationship: has_part UBERON:0002391 ! lymph relationship: part_of UBERON:0004536 ! lymph vasculature relationship: part_of UBERON:0006558 ! lymphatic part of lymphoid system xref: AAO:0011005 ! lymph vessel xref: SCTID:279089004 ! Entire lymphatic vessel synonym: "vas lymphaticum" RELATED LATIN [Wikipedia:Lymphatic_vessel] xref: http://upload.wikimedia.org/wikipedia/commons/4/44/Illu_lymph_capillary.jpg property_value: external_definition "A vessel that contains or conveys lymph.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011005", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "A network of blunt ended vessels lacking direct connection to the blood vascular system. These vessels collect and drain fluids and macromolecules from interstitial spaces throughout the animal. They derive from a subpopulation of endothelial cells and have walls that are much thinner than the blood carrying vessels. Lymphatic vessels are usually classified as either superficial or deep.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005105", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Tetrapods have evolved distinct lymphatic systems, in which lymphatic capillaries help drain most of the tissues of the body.[well established][VHOG]" xsd:string {external_class="VHOG:0001249", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.627", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229889 [Term] id: UBERON:0002049 name: vasculature def: "an interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face." [ZFA:0005249] comment: see also: vascular system. Consider merging? subset: uberon_slim subset: vertebrate_core synonym: "vascular network" EXACT [FMA:69050] xref: FMA:69050 ! Vasculature xref: ZFA:0005249 ! vasculature xref: BTO:0003718 ! vasculature xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Circulatory_System_en.svg/200px-Circulatory_System_en.svg.png is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: composed_primarily_of UBERON:0000055 ! vessel relationship: part_of UBERON:0007798 ! vascular system xref: TAO:0005249 ! vasculature [Term] id: UBERON:0004537 ! blood vasculature name: blood vasculature def: "a vascular network consisting of blood vessels." [UBERON:cjm] synonym: "set of blood vessels" EXACT [] synonym: "blood vascular network" EXACT [] xref: ZFA:0001079 ! blood vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: composed_primarily_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0004535 ! cardiovascular system xref: TAO:0001079 ! blood vasculature synonym: "blood vessels" RELATED [TAO:0001079] [Term] id: UBERON:0001981 name: blood vessel def: "A vessel through which blood circulates in the body." [BTO:0001102, Wikipedia:Blood_vessel] comment: note that FMA:63183 Blood vessel is categorized as 'general anatomical term'. Suggestion to map to region of vascular tree from Terry H at JAX. Taxon notes: annelids have blood vessels, but this class is not applicable to annelids. subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: BTO:0001102 xref: EFO:0000817 ! blood vessel xref: EHDAA:240 ! blood vessels xref: FMA:50722 ! region of vascular tree xref: FMA:63183 ! Blood vessel xref: GAID:169 ! blood vessel xref: VHOG:0001250 ! blood vessel xref: MA:0000060 ! blood vessel xref: MAT:0000393 ! blood vessel xref: OpenCyc:Mx4rvVjxlpwpEbGdrcN5Y29ycA xref: XAO:0001011 ! blood vessel xref: ncithesaurus:Blood_Vessel ! Blood Vessel xref: ZFA:0005314 ! blood vessel xref: OpenCyc:Mx4rvVjxlpwpEbGdrcN5Y29ycA ! blood vessel xref: NIF_GrossAnatomy:nlx_anat_090901 ! Blood vessel xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/29/Circulatory_System_en.svg/200px-Circulatory_System_en.svg.png xref: AEO:0000207 ! blood vessel xref: MESH:A07.231 ! blood vessel xref: EHDAA2:0003252 ! blood vessel is_a: UBERON:0007500 {source="EHDAA2"} ! epithelial tube open at both ends is_a: UBERON:0000055 ! vessel disjoint_from: UBERON:0001473 ! lymphatic vessel relationship: channel_for UBERON:0000178 ! blood relationship: part_of UBERON:0004537 ! blood vasculature relationship: develops_from UBERON:0004872 ! splanchnic layer of lateral plate mesoderm relationship: develops_from UBERON:0006965 {source="GO:0072360"} ! vascular cord relationship: has_function_in GO:0008015 ! blood circulation relationship: has_part CL:0000071 {source="AEO"} ! blood vessel endothelial cell xref: AAO:0011004 ! blood vessel xref: SCTID:361097006 ! Entire blood vessel xref: TAO:0002137 ! blood vessel synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] xref: http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg property_value: external_definition "Any of the vessels through which blood circulates in the body.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011004", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001250", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {external_class="VHOG:0001250", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH\, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0005847 [Term] id: UBERON:0001982 ! capillary name: capillary def: "Any of the smallest blood vessels connecting arterioles with venules." [Wikipedia:Capillary, ISBN10:0073040584] comment: Structure notes: capillaries lack tunica media and tunica adventitia; only the endothelial wall of the tunica intima belongs subset: uberon_slim subset: vertebrate_core synonym: "blood capillary" EXACT [] synonym: "capillary vessel" EXACT [] xref: FMA:63194 ! Capillary xref: VHOG:0001253 ! capillary xref: MA:0000065 ! capillary xref: OpenCyc:Mx4rvWEU-5wpEbGdrcN5Y29ycA xref: XAO:0000116 ! capillary xref: ncithesaurus:Capillary ! Capillary xref: BTO:0002045 ! capillary xref: ZFA:0005250 ! capillary xref: EFO:0001906 ! capillary xref: OpenCyc:Mx4rvWEU-5wpEbGdrcN5Y29ycA ! capillary xref: NIF_GrossAnatomy:nlx_anat_090902 ! Capillary xref: EMAPA:28039 ! capillary of developing vasculature of cortex xref: EMAPA:28075 ! capillary of developing vasculature of medulla xref: MESH:A07.231.432.410 ! capillary xref: EV:0100035 ! capillary is_a: UBERON:0010523 {source="ZFA"} ! microcirculatory vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: connects UBERON:0001979 ! venule intersection_of: connects UBERON:0001980 ! arteriole xref: AAO:0010252 ! capillary xref: TAO:0005250 ! capillary xref: http://upload.wikimedia.org/wikipedia/commons/2/2f/A_red_blood_cell_in_a_capillary,_pancreatic_tissue_-_TEM.jpg property_value: external_definition "Any of the tiny blood vessels connecting the arterioles to the venules.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010252", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {external_class="VHOG:0001253", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH\, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0935624 [Term] id: UBERON:0013141 name: capillary bed def: "A localized group of blood capillaries." [AEO:0001002] is_a: UBERON:0007502 {source="AEO"} ! epithelial plexus relationship: part_of UBERON:0002049 {source="FMA"} ! vasculature relationship: composed_primarily_of UBERON:0001982 ! capillary xref: FMA:45632 ! capillary bed xref: AEO:0001002 ! capillary bed [Term] id: UBERON:0006966 name: heart capillary def: "." [GO:0003248] intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0000333 name: intestinal gland def: "A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]." [UBERON:cjm] comment: Note that some sources treat 'intestinal gland' as synonymous with synonym: "glandula intestinalis" EXACT [FMA:15052] synonym: "gland of intestinal mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa" EXACT [OBOL:automatic] synonym: "gland of mucosa of intestine" EXACT [OBOL:automatic] synonym: "intestinal mucosa gland" EXACT [OBOL:automatic] synonym: "intestine mucosa gland" EXACT [OBOL:automatic] synonym: "mucosa of intestine gland" EXACT [OBOL:automatic] synonym: "bowel mucosa gland" EXACT [OBOL:automatic] synonym: "bowel mucosa of organ gland" EXACT [OBOL:automatic] synonym: "bowel mucous membrane gland" EXACT [OBOL:automatic] synonym: "bowel organ mucosa gland" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of bowel mucous membrane" EXACT [OBOL:automatic] synonym: "gland of bowel organ mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of intestine mucous membrane" EXACT [OBOL:automatic] synonym: "gland of intestine organ mucosa" EXACT [OBOL:automatic] synonym: "gland of mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of intestine" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of bowel" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of intestine" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of intestine" EXACT [OBOL:automatic] synonym: "intestine mucosa of organ gland" EXACT [OBOL:automatic] synonym: "intestine mucous membrane gland" EXACT [OBOL:automatic] synonym: "intestine organ mucosa gland" EXACT [OBOL:automatic] synonym: "mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of intestine gland" EXACT [OBOL:automatic] synonym: "mucous membrane of bowel gland" EXACT [OBOL:automatic] synonym: "mucous membrane of intestine gland" EXACT [OBOL:automatic] synonym: "organ mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "organ mucosa of intestine gland" EXACT [OBOL:automatic] synonym: "crypt of Lieberkuehn" RELATED [BTO:0000640] synonym: "gland of Lieberkuehn" RELATED [BTO:0000640] synonym: "Lieberkuehn`s gland" RELATED [BTO:0000640] synonym: "glandulae intestinales" RELATED [] xref: BTO:0000640 ! intestinal gland xref: FMA:15052 ! Intestinal gland is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001242 ! intestinal mucosa relationship: part_of UBERON:0001242 ! intestinal mucosa xref: SCTID:266297002 ! Entire intestinal gland subset: organ_slim [Term] id: UBERON:0001983 name: crypt of Lieberkuhn def: "A gland found in the epithelial lining of the intestine and colon." [Wikipedia:Intestinal_crypt] synonym: "intestinal gland" BROAD [Wikipedia:Crypts_of_Lieberkuhn] synonym: "intestinal crypt" EXACT [] synonym: "intestinal crypts" EXACT PLURAL [] synonym: "lieberkuhn crypt" EXACT [] synonym: "Lieberkuhn crypt" EXACT [] synonym: "crypt of lieberkuhn" EXACT [] synonym: "crypt of Lieberkühn" EXACT [] synonym: "crypts of Lieberkühn" EXACT PLURAL [] xref: FMA:63621 ! Crypt of Lieberkuhn xref: MA:0001535 ! crypt of lieberkuhn xref: SCTID:118652008 ! Crypt of LieberkCHu et al. 2001." [ZFIN:curator, Wikipedia:Heart_valve#Atrioventricular_valves] comment: AO notes: in ZFA this is part of both atrium and ventricle, but we use a connecting relationship here; see also notes for left and right. subset: vertebrate_core synonym: "AV valve" EXACT [] xref: EHDAA:7421 ! atrioventricular valves xref: FMA:7233 ! Atrioventricular valve xref: galen:AtrioventricularValve xref: VHOG:0001472 ! atrioventricular valve xref: MA:0002789 ! atrioventricular valve xref: OpenCyc:Mx4rfCfdorrpEduAAAACs6hRXg xref: TAO:0005064 ! atrioventricular valve xref: ZFA:0005064 ! atrioventricular valve xref: OpenCyc:Mx4rfCfdorrpEduAAAACs6hRXg ! atrioventricular valve xref: EHDAA2:0000153 ! atrioventricular valves is_a: UBERON:0000946 ! cardial valve relationship: part_of UBERON:0011820 {source="EHDAA2"} ! atrioventricular region relationship: develops_from UBERON:0002062 {source="PMID:15797462", source="ZFA"} ! endocardial cushion relationship: connects UBERON:0002081 ! cardiac atrium relationship: connects UBERON:0002082 ! cardiac ventricle relationship: attaches_to UBERON:0004292 {source="FMA"} ! cardiac skeleton xref: SCTID:11124005 ! Atrioventricular valve property_value: external_definition "The atrioventricular valve has four distinct leaflets oriented anterior, posterior, left, and right of the atrioventricular orifice. Hu et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005064", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Valve in the heart through which blood flows from the atria to the ventricles. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001472", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/atrioventricular+valve", source="http://bgee.unil.ch/"} property_value: homology_notes "The conus arteriosus is the most distal part of the primitive fish heart and forms the connection between the ventricle and the ventral aorta. At the sinoatrial, the atrioventricular, and the ventriculoconal junctions, valves developed to prevent backflow of blood during relaxation of the preceding compartment.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001472", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002134 name: tricuspid valve def: "Atrioventricular valve which has as its parts the anterior, posterior and septal leaflets, attached to the fibrous ring of tricuspid valve.[FMA]" [Wikipedia:Tricuspid_valve, FMA:FMA] comment: AO notes: FMA part_ofs changed to connects subset: uberon_slim synonym: "right atrioventricular valve" EXACT [FMA:7234] xref: EHDAA:7427 ! tricuspid valve xref: FMA:7234 ! Tricuspid valve xref: GAID:567 ! tricuspid valve xref: VHOG:0000816 ! tricuspid valve xref: MA:0000090 ! tricuspid valve xref: ncithesaurus:Tricuspid_Valve ! Tricuspid Valve xref: galen:TricuspidValve ! tricuspid valve xref: OpenCyc:Mx4rvuWAAJwpEbGdrcN5Y29ycA ! tricuspid valve xref: RETIRED_EHDAA2:0002081 ! tricuspid valve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/20/Diagram_of_the_human_heart_%28cropped%29.svg/200px-Diagram_of_the_human_heart_%28cropped%29.svg.png xref: EMAPA:17873 ! tricuspid valve xref: MESH:A07.541.510.893 ! tricuspid valve intersection_of: UBERON:0002133 ! atrioventricular valve intersection_of: part_of UBERON:0005965 ! outflow part of right atrium relationship: connects UBERON:0002078 ! right atrium relationship: connects UBERON:0002080 ! heart right ventricle synonym: "valva atrioventricularis dextra" EXACT LATIN [FMA:TA, FMA:7234] synonym: "valvula tricuspidalis" RELATED LATIN [Wikipedia:Tricuspid_valve] xref: SCTID:181288007 ! Entire tricuspid valve xref: EHDAA2:0004029 ! tricuspid valve xref: http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg property_value: external_definition "The three-segmented valve of the heart that keeps blood in the right ventricle from flowing back into the right atrium. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000816", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/Tricuspid+valves", source="http://bgee.unil.ch/"} property_value: homology_notes "The mature AV (atrioventricular) valve of the adult zebrafish 2-chambered heart is structurally similar to the mammalian AV valves with stratified ECM (extracellular matrix) and supporting chordae tendineae. Therefore, the major cellular and molecular events of valve development are largely conserved among animals with hearts composed of multiple chambers.[well established][VHOG]" xsd:string {external_class="VHOG:0000816", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0040960 [Term] id: UBERON:0002135 ! mitral valve name: mitral valve def: "Atrioventricular valve which has as its parts the anterior and posterior leaflets, attached to the fibrous ring of mitral valve.[FMA]" [Wikipedia:Mitral_valve, FMA:FMA] comment: AO notes: FMA part_ofs changed to connects subset: uberon_slim synonym: "bicuspid valve" RELATED [] synonym: "left atrioventricular valve" EXACT [] xref: FMA:7235 ! Mitral valve xref: GAID:565 ! mitral valve xref: VHOG:0000817 ! mitral valve xref: MA:0000088 ! mitral valve xref: OpenCyc:Mx4rv4l2nJwpEbGdrcN5Y29ycA xref: ncithesaurus:Mitral_Valve ! Mitral Valve xref: galen:MitralValve ! mitral valve xref: OpenCyc:Mx4rv4l2nJwpEbGdrcN5Y29ycA ! mitral valve xref: EHDAA2:0000168 ! bicuspid valve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/20/Diagram_of_the_human_heart_%28cropped%29.svg/200px-Diagram_of_the_human_heart_%28cropped%29.svg.png xref: EMAPA:17871 ! mitral valve xref: MESH:A07.541.510.507 ! mitral valve xref: EFO:0003933 ! mitral valve intersection_of: UBERON:0002133 ! atrioventricular valve intersection_of: part_of UBERON:0005966 ! outflow part of left atrium relationship: attaches_to UBERON:0005995 {source="FMA"} ! mitral valve anulus relationship: connects UBERON:0002079 {source="FMA"} ! left atrium relationship: connects UBERON:0002084 {source="FMA"} ! heart left ventricle synonym: "valva atrioventricularis sinistra" EXACT LATIN [FMA:TA, FMA:7235] synonym: "valva mitralis" RELATED LATIN [Wikipedia:Mitral_valve] xref: SCTID:181286006 ! Entire mitral valve xref: http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg property_value: external_definition "A valve of the heart, composed of two triangular flaps, that is located between the left atrium and left ventricle and regulates blood flow between these chambers. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000817", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/mitral+valve", source="http://bgee.unil.ch/"} property_value: homology_notes "The mature AV (atrioventricular) valve of the adult zebrafish 2-chambered heart is structurally similar to the mammalian AV valves with stratified ECM (extracellular matrix) and supporting chordae tendineae. Therefore, the major cellular and molecular events of valve development are largely conserved among animals with hearts composed of multiple chambers.[well established][VHOG]" xsd:string {external_class="VHOG:0000817", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0026264 [Term] id: UBERON:0002137 ! aortic valve name: aortic valve def: "Cardiac valve which has as its parts the anterior, right posterior and left posterior cusps, attached to the fibrous ring of aortic valve.[FMA]" [Wikipedia:Aortic_valve, FMA:FMA] comment: Human variation: It is normally tricuspid (with three leaflets), although in 1% of the population it is found to be congenitally bicuspid (two leaflets) subset: uberon_slim xref: EHDAA:4410 ! aortic valve xref: FMA:7236 ! Aortic valve xref: GAID:563 ! aortic valve xref: galen:AorticValve xref: VHOG:0000815 ! aortic valve xref: MA:0000087 ! aortic valve xref: OpenCyc:Mx4rv5914JwpEbGdrcN5Y29ycA xref: ncithesaurus:Aortic_Valve ! Aortic Valve xref: OpenCyc:Mx4rv5914JwpEbGdrcN5Y29ycA ! aortic valve xref: EHDAA2:0000134 ! aortic valve xref: BTO:0004628 ! aortic valve xref: EMAPA:17870 ! aortic valve xref: MESH:A07.541.510.110 ! aortic valve xref: EFO:0003879 ! aortic valve is_a: UBERON:0005623 {source="MA"} ! semi-lunar valves relationship: part_of UBERON:0005956 ! outflow part of left ventricle xref: SCTID:181287002 ! Entire aortic valve synonym: "valva aortae" RELATED LATIN [Wikipedia:Aortic_valve] xref: http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg property_value: external_definition "The valve between the left ventricle of the heart and the ascending aorta, consisting of three semilunar cusps. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000815", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/aortic+valve", source="http://bgee.unil.ch/"} xref: UMLS:C0003501 [Term] id: UBERON:0002088 name: lateral thoracic vein def: "The lateral thoracic vein is a tributary of the axillary vein. It runs with the lateral thoracic artery and drains the Serratus anterior muscle and the Pectoralis major muscle. Normally, the thoracoepigastric vein exists between this vein and superficial epigastric vein (a tributary of femoral vein), to act as a shunt for blood if the portal system (through the liver) develops hypertension or a blockage. [WP,unvetted]." [Wikipedia:Lateral_thoracic_vein] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:71210 ! Lateral thoracic vein xref: MA:0002162 ! lateral thoracic vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Gray576.png/200px-Gray576.png is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein relationship: tributary_of UBERON:0000985 {source="FMA/obol"} ! axillary vein xref: SCTID:53595001 ! Entire lateral thoracic vein synonym: "vena thoracica lateralis" RELATED LATIN [Wikipedia:Lateral_thoracic_vein] xref: http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray576.png [Term] id: UBERON:0002089 name: thoracodorsal vein comment: This class was created automatically from a combination of ontologies xref: FMA:71213 ! Thoracodorsal vein xref: MA:0002238 ! thoracodorsal vein is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein relationship: tributary_of UBERON:0000985 {source="FMA/obol"} ! axillary vein [Term] id: UBERON:0011137 ! axial skeletal system name: axial skeletal system def: "Subdivision of the skeletal system which consists of the axial skeleton plus associated joints." [UBERON:cjm] is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system xref: FMA:7483 ! axial skeletal system [Term] id: UBERON:0011249 ! appendicular skeletal system name: appendicular skeletal system def: "Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints." [UBERON:cjm] is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system xref: FMA:7484 ! appendicular skeletal system xref: VSAO:0000306 ! appendicular skeletal system xref: VHOG:0001666 ! appendicular skeleton (also: UBERON:0002091 'entire appendicular skeleton') property_value: external_definition "Skeletal system which consists of the appendicular skeleton plus associated joints.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000306", date_retrieved="2012-08-14", source="UBERON:cjm"} [Term] id: UBERON:0005944 name: axial skeleton plus cranial skeleton def: "Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]." [VSAO:0000056, FMA:71221, Wikipedia:Axial_skeleton, UBERONREF:0000008] comment: See [UBERONREF:0000008] subset: uberon_slim xref: MA:0000308 ! axial skeleton xref: ncithesaurus:Axial_Skeleton ! Axial Skeleton xref: EMAPA:18043 ! axial skeleton of skeleton of tail of embryo (also: UBERON:0002090 'postcranial axial skeleton') xref: EMAPA:17214 ! axial skeleton of skeleton of embryo (also: UBERON:0002090 'postcranial axial skeleton') xref: VSAO:0000056 ! axial skeleton is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0004288 ! skeleton relationship: part_of UBERON:0011137 ! axial skeletal system relationship: develops_from UBERON:0003089 ! sclerotome relationship: connected_to UBERON:0002091 ! appendicular skeleton xref: SCTID:361725000 ! Entire axial skeleton xref: AAO:0000963 ! axial skeleton xref: XAO:0004011 ! axial skeleton synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Axial_skeleton_diagram.svg property_value: external_definition "Skeletal subdivision of the central body axis including the cranium, vertebrae, notochord, ribs, and sternum.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000056", date_retrieved="2012-08-14", source="PSPUB:0000170"} xref: UMLS:C0222645 [Term] id: UBERON:0011138 ! post-cranial axial skeletal system name: post-cranial axial skeletal system synonym: "axial skeletal system" BROAD [http://purl.obolibrary.org/obo/uberon/references/reference_0000008] def: "Subdivision of the skeletal system which consists of the post-cranial axial skeleton plus associated joints." [UBERON:cjm] is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: develops_from UBERON:0003089 {source="cjm"} ! sclerotome property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000003" xsd:anyURI [Term] id: UBERON:0002090 name: postcranial axial skeleton def: "The post-cranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]." [ZFA:0000317, https://sourceforge.net/tracker/?func=detail&aid=2983975&group_id=76834&atid=974957, https://sourceforge.net/tracker/?func=detail&atid=1205376&aid=2983977&group_id=76834] comment: previous some AOs had used the term 'axial skeleton' to include the skull. This is being resolved (see tracker items above). Status: MA - fixed. subset: uberon_slim subset: vertebrate_core synonym: "axial skeleton" BROAD [FMA:71221, UBERONREF:0000008] synonym: "post-cranial axial skeleton" EXACT [] xref: FMA:71221 ! Axial skeleton xref: EHDAA2:0000161 ! axial skeleton xref: AAO:0000034 ! axial_skeleton xref: EHDAA:5049 ! axial skeleton xref: VHOG:0000317 ! axial skeleton xref: MA:0002986 ! post-cranial axial skeleton xref: MAT:0000148 ! axial skeleton xref: MIAA:0000148 ! axial skeleton xref: TAO:0000317 ! postcranial axial skeleton xref: XAO:0003073 ! postcranial axial skeleton xref: ZFA:0000317 ! postcranial axial skeleton xref: EMAPA:18043 ! axial skeleton of skeleton of tail of embryo (also: UBERON:0005944 'axial skeleton plus cranial skeleton') xref: EMAPA:17214 ! axial skeleton of skeleton of embryo (also: UBERON:0005944 'axial skeleton plus cranial skeleton') xref: VSAO:0000093 ! postcranial axial skeleton is_a: UBERON:0010912 ! subdivision of skeleton relationship: develops_from UBERON:0003089 ! sclerotome relationship: part_of UBERON:0005944 ! axial skeleton plus cranial skeleton relationship: part_of UBERON:0011138 ! post-cranial axial skeletal system property_value: external_definition "The axial skeleton is formed by the vertebral column, a metameric, semi-flexible, arched bar located in the dorsal part of the trunk, and is formed by a series of cartilaginous or bony vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000034", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The post-cranial structural components forming the long axis of the vertebrate body; usually consists of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000317", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Skeletal subdivision of the central body axis including vertebrae, notochord, ribs, and sternum.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000093", date_retrieved="2012-08-14", source="PSPUB:0000170"} property_value: homology_notes "The axial musculoskeletal system represents the plesiomorphic locomotor engine of the vertebrate body, playing a central role in locomotion. In craniates, the evolution of the postcranial skeleton is characterized by two major transformations. First, the axial skeleton became increasingly functionally and morphologically regionalized. Second, the axial-based locomotion plesiomorphic for craniates became progressively appendage-based with the evolution of extremities in tetrapods.[well established][VHOG]" xsd:string {external_class="VHOG:0000317", ontology="VHOG", source="DOI:10.1186/1742-9994-8-4 Schilling N\, Evolution of the axial system in craniates: morphology and function of the perivertebral musculature. Frontiers in Zoology (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002091 ! appendicular skeleton name: appendicular skeleton def: "Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]." [UBERON:cjm, Wikipedia:Appendicular_skeleton, UBERONREF:0000003] comment: Note that ontologies differ in whether they treat the term appendicular skeleton as being the entire set of bones in the limbs, or whether the fore and hind limbs/fins are treated as seperate appendicular skeletons. Here we follow FMA, and treat the appendicular skeleton as the sum total of skeletal elements in the organism (this is evidenced by the fact that in FMA, skeleton of left/right upper/lower limb is part_of a appendicular skeleton, and subtypes of 'subdivision of appendicular skeleton'). We have separate classes such as 'skeleton of limb', and 'skeleton of hindlimb' for the 4 parts of the appendicular skeleton. In future the ZFA/TAO classes may be moved. subset: uberon_slim subset: vertebrate_core synonym: "entire appendicular skeleton" EXACT [http://purl.obolibrary.org/obo/uberon/tracker/59] synonym: "appendicular skeleton" EXACT [] synonym: "paired fin skeleton" NARROW SENSU [] xref: AAO:0000747 ! appendicular_skeleton xref: FMA:71222 ! Appendicular skeleton xref: MA:0000290 ! appendicular skeleton xref: MAT:0000278 ! paired fin skeleton xref: MIAA:0000278 ! paired fin skeleton xref: XAO:0003166 ! appendicular skeleton xref: ncithesaurus:Appendicular_Skeleton ! Appendicular Skeleton xref: EFO:0000951 ! paired fin skeleton xref: VSAO:0000076 ! appendicular skeleton is_a: UBERON:0010912 ! subdivision of skeleton relationship: overlaps UBERON:0000026 ! appendage relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of UBERON:0011249 ! appendicular skeletal system xref: SCTID:322050006 ! Entire appendicular skeleton synonym: "skeleton appendiculare" RELATED LATIN [Wikipedia:Appendicular_skeleton] xref: http://upload.wikimedia.org/wikipedia/commons/7/7c/Appendicular_skeleton_diagram.svg property_value: external_definition "The pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hind limbs, form the appendicular skeleton.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000747", date_retrieved="2012-06-20", source="AAO:LAP"} xref: VHOG:0001666 ! appendicular skeleton (also: UBERON:0011249 'appendicular skeletal system') property_value: external_definition "Skeletal system that consists of the paired fins (pectoral or pelvic fins).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000027", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_definition "Skeletal subdivision consisting of all the skeletal elements in the pectoral and pelvic appendage complexes.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000076", date_retrieved="2012-08-14", source="PSPUB:0000170", source="UBERON:cjm"} xref: UMLS:C0222646 [Term] id: UBERON:0002092 name: brain dura mater def: "the fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer." [MP:0009025] synonym: "dura mater of brain" EXACT [] synonym: "cranial dura mater" EXACT [FMA:71236] synonym: "dura mater encephali" EXACT [] xref: FMA:71236 ! cranial dura mater xref: VHOG:0000270 ! brain dura mater xref: MA:0000815 ! brain dura mater xref: ncithesaurus:Cerebral_Dura_Mater ! Brain Dura Mater xref: EMAPA:17766 ! dura mater of meninges of diencephalon of forebrain (also: UBERON:0003561 'forebrain dura mater') (also: UBERON:0003564 'diencephalon dura mater') xref: EMAPA:17785 ! dura mater of meninges of hindbrain of brain of central nervous system of nervous system of organ system (also: UBERON:0003565 'hindbrain dura mater') xref: EMAPA:17793 ! dura mater of meninges of midbrain (also: UBERON:0003562 'midbrain dura mater') xref: EV:0100313 ! dura mater (also: UBERON:0002363 'dura mater') is_a: UBERON:0002363 ! dura mater intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0000955 ! brain xref: SCTID:309321003 ! Entire brain dura mater property_value: external_definition "The outermost and densest membrane of the three mammalian meninges covering the brain and spinal cord. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000270", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000270", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0459393 [Term] id: UBERON:0002093 name: spinal dura mater def: "A dura mater that is part of a spinal cord [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "dura mater of spinal cord" EXACT [] synonym: "spinal cord dura mater" EXACT [] synonym: "dura mater of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "spinal cord dura mater of neuraxis" EXACT [OBOL:automatic] xref: FMA:71237 ! Spinal dura mater xref: VHOG:0000411 ! spinal cord dura mater xref: MA:0001132 ! spinal cord dura mater xref: ncithesaurus:Spinal_Cord_Dura_Mater ! Spinal Cord Dura Mater xref: EMAPA:17806 ! dura mater of meninges of spinal cord of central nervous system of nervous system of organ system is_a: UBERON:0002363 ! dura mater intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0002240 ! spinal cord xref: SCTID:362302001 ! Entire spinal dura mater subset: organ_slim property_value: external_definition "The outermost and densest membrane of the three mammalian meninges covering the brain and spinal cord. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000411", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000411", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0228124 [Term] id: UBERON:0004142 name: outflow tract septum def: "The outflow tract septum is a partition in the outflow tract" [GO:0003148] intersection_of: UBERON:0002099 ! cardiac septum intersection_of: part_of UBERON:0004145 ! outflow tract [Term] id: UBERON:0006207 alt_id: UBERON:0005999 name: aortico-pulmonary spiral septum def: "the spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions." [Wikipedia:Aorticopulmonary_septum, MP:0010650] synonym: "spiral septum" RELATED [Wikipedia:Aorticopulmonary_septum] synonym: "aortic septum" RELATED [Wikipedia:Aorticopulmonary_septum] synonym: "aortico-pulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum] synonym: "aorticopulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum] synonym: "septum aorticopulmonale" EXACT LATIN [Wikipedia:Aorticopulmonary_septum] subset: emapa_ehdaa2 xref: EMAPA:16827 ! aortico-pulmonary spiral septum xref: EHDAA2:0000136 ! aortico-pulmonary spiral septum xref: VHOG:0000502 ! aortico-pulmonary spiral septum xref: EHDAA:2592 ! aortico-pulmonary spiral septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: adjacent_to UBERON:0002333 ! pulmonary trunk intersection_of: adjacent_to UBERON:0005805 ! dorsal aorta relationship: part_of UBERON:0004145 {source="EMAPA"} ! outflow tract relationship: develops_from UBERON:0000095 {source="Wikipedia", source="PMID:6844926"} ! cardiac neural crest xref: http://upload.wikimedia.org/wikipedia/commons/b/b9/Gray470.png [Term] id: UBERON:0002094 name: interventricular septum def: "Cardiac septum which separates the right ventricle from the left ventricle.[FMA]" [Wikipedia:Interventricular_septum, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "ventricular septum" RELATED [MA:0000085] synonym: "heart ventricular septum" EXACT [MA:0000085] synonym: "heart interventricular septum" EXACT [MA:0000085] synonym: "interventricular septum of heart" RELATED [BTO:0002483] synonym: "interventriculare cordis" RELATED [BTO:0002483] xref: EHDAA:2603 ! interventricular septum xref: FMA:7133 ! Interventricular septum xref: galen:InterventricularSeptum xref: VHOG:0000386 ! interventricular septum xref: MA:0000085 ! heart ventricular septum xref: ncithesaurus:Interventricular_Septum ! Interventricular Septum xref: BTO:0002483 ! interventricular septum xref: EFO:0001956 ! interventricular septum xref: OpenCyc:Mx4rwA7lp5wpEbGdrcN5Y29ycA ! ventricular septum xref: EHDAA2:0000885 ! interventricular septum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/96/Gray498.png/200px-Gray498.png xref: EMAPA:17333 ! interventricular septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: adjacent_to UBERON:0002084 ! left ventricle intersection_of: adjacent_to UBERON:0002080 ! right ventricle xref: SCTID:362019005 ! Entire interventricular septum synonym: "s. interventriculare cordis" RELATED LATIN [Wikipedia:Interventricular_septum] xref: http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png property_value: external_definition "The partition separating the right and left ventricles of the heart. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000386", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/interventricular+septum", source="http://bgee.unil.ch/"} property_value: homology_notes "The two most progressive vertebrate classes, the birds and mammals, have completed the ventricular septum and at long last have completely separated the two blood streams along the length of the major heart chambers. This development has obviously been brought about independently in the two cases, since mammals and birds have evolved independently from primitive reptiles.[well established][VHOG]" xsd:string {external_class="VHOG:0000386", ontology="VHOG", source="ISBN:978-0721676678 Romer AS\, Vertebrate body (1970) p.430", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0225870 [Term] id: UBERON:0013220 name: foramen of Panizza def: "The Foramen of Panizza is a hole with that connects the left and right aorta as they leave the heart of all animals of the order Crocodilia. Crocodilians have a completely separated ventricle with deoxygenated blood from the body, or systemic circulation, in the right ventricle and oxygenated blood from the lungs, or pulmonary circulation, in the left ventricle, as in birds and mammals. Two vessels, the left aorta and the pulmonary artery, exit the right ventricle. Blood from the right ventricle goes to the lungs through the pulmonary artery, as in mammals and birds. However, when a unique active valve leading to the pulmonary artery contracts, pressure in the right ventricle can increase and blood can leave the right ventricle, enter the left aortic arch, and therefore bypass the pulmonary circulation. The foramen of panizza connects the left and right aorta. Deoxygenated blood from the right ventricle, sitting in the left aorta, can flow into the right aorta through the foramen of panizza. When the heart is relaxed, some oxygenated blood from the left ventricle, sitting in the right aorta, can flow into the left aorta across the foramen of panizza. However, some species of Crocodilians have regulatory sphincters that prevent unwanted flow of blood through the foramen of panizza during non-diving." [Wikipedia:Foramen_of_Panizza] is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0004535 {source="Wikipedia"} ! cardiovascular system relationship: connects UBERON:0000947 ! aorta relationship: connects UBERON:0000947 {cardinality="2"} ! aorta relationship: part_of UBERON:0000948 ! heart relationship: only_in_taxon NCBITaxon:8493 {source="Wikipedia"} ! Crocodylidae [Term] id: UBERON:0002095 name: mesentery def: "Anatomical organ component composed of a double layer of serous membrane that suspends a viscus from the body wall or connects adjacent viscera and in doing so conveys blood vessels, lymphatics and nerves to and from the viscera. Examples: greater omentum, broad ligament of uterus, sigmoid mesocolon." [FMA:7144, Wikipedia:Mesentery, Wikipedia:Mesentery#Mesentery_.28general.29] comment: Note that in Uberon, this term is used in the generic sense, not necessarily restricted to the peritoneum, consistent with FMA. WP: "In anatomy, the mesentery is the double layer of peritoneum that suspends the jejunum and ileum from the posterior wall of the abdomen. Its meaning, however, is frequently extended to include double layers of peritoneum connecting various components of the abdominal cavity.". TODO - check. Consider FMA:259286 - Region of mesentery. subset: uberon_slim subset: vertebrate_core synonym: "mesentery (generic)" EXACT [Wikipedia:Mesentery] synonym: "generic mesentery" EXACT [Wikipedia:Mesentery] xref: BTO:0001380 xref: FMA:7144 ! Mesentery xref: GAID:21 ! mesentery xref: ncithesaurus:Mesentery ! Mesentery xref: galen:Mesentery ! mesentery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/19/Gray1038.png/200px-Gray1038.png xref: MESH:A01.047.025.600.451 ! mesentery xref: EV:0100083 ! mesentery is_a: UBERON:0000042 ! serous membrane relationship: develops_from UBERON:0002296 {evidence="definitional"} ! dorsal mesentery xref: AAO:0011061 ! mesentery xref: SCTID:362707009 ! Entire mesentery xref: http://upload.wikimedia.org/wikipedia/commons/1/19/Gray1038.png property_value: has_relational_adjective "mesenteric" xsd:string xref: UMLS:C0025474 [Term] id: UBERON:0007826 name: peritoneal mesentery def: "A double layer composed of peritoneum that attaches the visceral organs to the body wall." [ZFIN:curator] xref: FMA:20570 ! peritoneal mesentery xref: TAO:0005129 ! mesentery xref: XAO:0000138 ! mesentery xref: ZFA:0005129 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0002358 ! peritoneum relationship: part_of UBERON:0001178 {source="FMA"} ! visceral peritoneum relationship: part_of UBERON:0002358 {source="ZFA"} ! peritoneum [Term] id: UBERON:0001170 name: mesentery of small intestine def: "the peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]." [Wikipedia:Mesentery#Mesentery_.28proper.29] synonym: "mesentery proper" EXACT [FMA:14643] synonym: "mesentery (proper)" EXACT [Wikipedia:Mesentery] synonym: "small intestinal mesentery" EXACT [FMA:14643] synonym: "small intestine mesentery" EXACT [OBOL:automatic] xref: FMA:14643 ! Mesentery of small intestine xref: MA:0001555 ! small intestine mesentery is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0002108 ! small intestine xref: SCTID:245456008 ! Entire small intestine mesentery [Term] id: UBERON:0002098 name: apex of heart def: "The apex of the heart is the lowest superficial part of the heart. It is directed downward, forward, and to the left, and is overlapped by the left lung and pleura. [WP,unvetted]." [Wikipedia:Apex_of_the_heart] comment: Note that FMA also has terms for the apical zone subset: uberon_slim synonym: "cardiac apex" EXACT [FMA:7164] synonym: "heart apex" EXACT [] synonym: "apex cordis" EXACT LATIN [] xref: FMA:7164 ! Apex of heart xref: MA:0000488 ! heart apex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/46/Gray492.png/200px-Gray492.png is_a: UBERON:0006983 {source="FMA"} ! anatomical point relationship: part_of UBERON:0000948 ! heart xref: ncithesaurus:Apex_of_the_Heart ! Apex of the Heart xref: SCTID:362009004 ! Entire apex of heart xref: http://upload.wikimedia.org/wikipedia/commons/4/46/Gray492.png xref: UMLS:C0225811 [Term] id: UBERON:0002099 name: cardiac septum def: "The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles." [MESH:A07.541.459] comment: Note in GO, septum morphogenesis is part of cardiac chamber morphogenesis; need to add axioms to infer this. Taxon notes: "Terrestrial vertebrates have divided hearts in which septae separate the oxygenated and deoxygenated blood within the pulmonary and systemic circulations" subset: uberon_slim synonym: "cardiac septa" EXACT PLURAL [] synonym: "heart septum" EXACT [] synonym: "heart septa" EXACT PLURAL [] synonym: "septum of heart" EXACT [] xref: FMA:7180 ! Cardiac septum xref: GAID:562 ! heart septum xref: MA:0000083 ! heart septum xref: ncithesaurus:Heart_Septum ! Heart Septum xref: MESH:A07.541.459 ! heart septum is_a: UBERON:0003037 ! septum intersection_of: UBERON:0003037 ! septum intersection_of: part_of UBERON:0000948 ! heart relationship: adjacent_to UBERON:0004151 ! cardiac chamber relationship: part_of UBERON:0000948 ! heart xref: SCTID:362014000 ! Entire cardiac septum xref: XAO:0004141 ! spiral septum xref: UMLS:C0018819 [Term] id: UBERON:0006057 ! multi-segment region name: obsolete multi-segment region is_obsolete: true [Term] id: UBERON:0006058 ! multi-limb segment region name: multi-limb segment region def: "A collection of two or more connected limb segments. Examples: arm (comprising stylopod and zeugopod regions)." [UBERON:cjm] is_a: UBERON:0000477 ! anatomical cluster relationship: has_part UBERON:0002529 ! limb segment [Term] id: UBERON:0001460 name: arm def: "The part of the forelimb extending from the shoulder to the autopod[cjm]." [Wikipedia:Arm] comment: This class refers to the combination of the stylopod and zeugopod of a forelimb. Sometimes (cf FMA), 'arm' denotes the stylopod only; sometimes (cf MA), 'arm' denotes the part of the forelimb covering both (i.e. shoulder to hand). Also note distinction between arm and forelimb: hand is part of forelimb, but not part of arm. Editor note: currently declared as overlapping hand, as AOs disagree over whether some wrist parts are in the arm or hand subset: uberon_slim synonym: "upper extremity" RELATED [MESH:A01.378.800] xref: EHDAA:4164 ! arm xref: EHDAA:6210 ! arm xref: EHDAA:8275 ! arm xref: GAID:52 ! arm xref: VHOG:0000339 ! arm xref: MA:0000033 ! arm xref: OpenCyc:Mx4rvVjp5ZwpEbGdrcN5Y29ycA xref: BTO:0001435 ! arm xref: EFO:0001410 ! arm xref: OpenCyc:Mx4rvVjp5ZwpEbGdrcN5Y29ycA ! arm xref: EHDAA2:0000140 ! arm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Upperarm.jpg/200px-Upperarm.jpg xref: MESH:A01.378.800.075 ! arm (also: UBERON:0003822 'forelimb stylopod') xref: MESH:A01.378.800 ! upper extremity xref: EMAPA:17413 ! arm of forelimb is_a: UBERON:0006058 ! multi-limb segment region relationship: part_of UBERON:0002102 ! forelimb relationship: distally_connected_to UBERON:0002398 ! manus relationship: proximally_connected_to UBERON:0001467 ! shoulder synonym: "brachium" RELATED LATIN [Wikipedia:Arm] xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Upperarm.jpg property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000339", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0000978 ! leg name: leg def: "The portion of the hindlimb that contains both the stylopod and zeugopod." [Wikipedia:Leg#Limb] comment: The term leg can mean: [1] an appendage on which an animal walks [2] the entire hindlimb of a tetrapod [3] the segment of a human leg between knee and ankle (cf FMA) [4] the region of a hindlimb include the stylopod and zeugopod, but excluding the autopod. We define this class as [4], and thus 'leg' is compltely analagous to 'arm'. For [1], see the class 'locomotive weight-bearing appendage'. For [2] we use 'hindlimb'. For [3] we use the less open to misinterpretation 'hindlimb zeugopod'. Editor note: currently declared as overlapping foot, as AOs disagree over whether some ankle parts are in the leg or foot subset: uberon_slim synonym: "tetrapod leg" EXACT [] synonym: "lower extremity" RELATED [MESH:A01.378.610] xref: BTO:0000721 xref: EHDAA:5151 ! leg xref: EHDAA:6176 ! leg xref: EHDAA:8289 ! leg xref: GAID:49 ! leg xref: VHOG:0000345 ! leg xref: MA:0000047 ! leg xref: OpenCyc:Mx4rvViYzZwpEbGdrcN5Y29ycA xref: EFO:0001411 ! leg xref: EHDAA2:0000972 ! leg xref: EMAPA:17489 ! leg of hindlimb xref: MESH:A01.378.610 ! lower extremity is_a: UBERON:0006058 ! multi-limb segment region relationship: part_of UBERON:0002103 ! hindlimb relationship: distally_connected_to UBERON:0002387 ! pes relationship: proximally_connected_to UBERON:0001464 ! hip property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000345", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005894 ! locomotive weight-bearing appendage name: locomotive weight-bearing appendage def: "A leg is a limb on which an animal walks and stands (GO:0035110)." [GO:0035110, Wikipedia:Leg] comment: Functional grouping, currently encompasses vertebrate and insect legs. This class was originally introduced to support GO:0035110, but this has been obsoleted. subset: functional_classification synonym: "leg" RELATED [] is_a: UBERON:0000026 ! appendage [Term] id: UBERON:0005895 ! insect leg name: insect leg def: "The walking appendages of each segment of the ventral adult external thorax[FBbt]. A leg derived from an imaginal disc[GO]." [FBbt:00004640, GO:0007480] synonym: "imaginal disc-derived leg" EXACT [GO:0007480] xref: FBbt:00004640 ! leg xref: MAT:0000095 ! limb sensu invertebrata xref: MIAA:0000095 ! limb sensu invertebrata xref: TGMA:0000164 ! adult leg is_a: UBERON:0005894 ! locomotive weight-bearing appendage [Term] id: UBERON:0004708 ! limb/fin alt_id: UBERON:0009872 name: limb/fin comment: this class is the union of the classes limb, pectoral fin and pelvic fin. synonym: "jointed paired lateral appendage" NARROW [UBERON:cjm] synonym: "limb or fin" EXACT [UBERON:cjm] synonym: "girdle-associated appendage" EXACT [UBERON:cjm] synonym: "pectoral or pelvic appendage" EXACT [UBERON:cjm] synonym: "pelvic/pectoral appendage" EXACT [UBERON:cjm] synonym: "paired appendage" EXACT [VSAO:0000067] is_a: UBERON:0000026 {source="VSAO"} ! appendage relationship: part_of UBERON:0010707 {source="VSAO"} ! appendage girdle complex intersection_of: UBERON:0000026 ! appendage intersection_of: part_of UBERON:0010707 ! appendage girdle complex relationship: connected_to UBERON:0007823 ! appendage girdle region relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: develops_from UBERON:0004357 {evidence="definitional"} ! limb/fin bud xref: VSAO:0000067 ! paired appendage def: "An appendage that is part of a appendage girdle complex." [OBOL:automatic] [Term] id: UBERON:0004709 ! pelvic appendage alt_id: UBERON:0009876 name: pelvic appendage def: "Paired appendage that consists of the posterior appendicular skeleton and associated soft and hard tissues, but excludes the pelvic girdle and its associated soft and hard tissues." [VSAO:0000150] comment: VSAO notes - in contrast to VSAO, we include separate subclasses for limbs and fins synonym: "hindlimb/pelvic fin" EXACT [UBERON:cjm] synonym: "pelvic appendage" EXACT [VSAO:0000126] synonym: "pelvic limb/fin" EXACT [UBERON:cjm] intersection_of: UBERON:0004708 ! limb/fin intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: connected_to UBERON:0001271 ! pelvic girdle region relationship: develops_from UBERON:0005420 {evidence="definitional"} ! pelvic appendage bud xref: VSAO:0000126 ! pelvic appendage synonym: "posterior paired appendage" EXACT [VSAO:0000126] [Term] id: UBERON:0004710 ! pectoral appendage alt_id: UBERON:0009875 name: pectoral appendage def: "Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues." [VSAO:0000150-modified] synonym: "anterior paired appendage" EXACT [VSAO:0000148] synonym: "forelimb/pectoral fin" EXACT [UBERON:cjm] synonym: "anterior limb/fin" EXACT [UBERON:cjm] synonym: "pectoral limb/fin" EXACT [UBERON:cjm] synonym: "forelimb or pectoral fin" EXACT [UBERON:cjm] synonym: "forelimb - pectoral fin" EXACT [VHOG:0001753] intersection_of: UBERON:0004708 ! limb/fin intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: connected_to UBERON:0001421 ! pectoral girdle region relationship: develops_from UBERON:0005419 {evidence="definitional"} ! pectoral appendage bud xref: VSAO:0000125 ! pectoral appendage xref: VHOG:0001753 ! forelimb - pectoral fin property_value: homology_notes "While the skeletons of teleost pectoral fins and tetrapod forelimbs are homologous at the level of endoskeletal radials, teleosts and tetrapods do not share homologous skeletal elements at the level of 'individuated' pro-, meso-, and metapterygia. Among osteichthyans, only basal actinopterygians retain the full complement of elements present in non-osteichthyan gnathostomes.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001753", ontology="VHOG", source="DOI:10.1002/jmor.10264 Davis MC\, Shubin NH\, Force A\, Pectoral fin and girdle development in the basal actinopterygians Polyodon spathula and Acipenser transmontanus. Journal of Morphology (2004)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005896 ! jointed/prehensile appendage name: jointed/prehensile appendage def: "A jointed or prehensible appendage used for locomotion or manipulation. Examples: human arm, human leg, octopus tentacle, insect limb[Wikipedia]. A limb is an appendage of an animal used for locomotion or grasping. For example a leg, arm or some types of fin[GO]." [GO:0035108, Wikipedia:Limb_(anatomy)] comment: Usage notes: this class was originally introduced to account for the previously vague use of the term 'limb' in GO. synonym: "limb" RELATED [BTO:0001492, AEO:0000172, GO:0035108] synonym: "extremity" RELATED [] synonym: "extremities" RELATED PLURAL [] synonym: "extremitaet" RELATED [BTO:0001492] consider: ncithesaurus:Extremities ! Extremities consider: AEO:0000172 ! limb is_obsolete: true [Term] id: UBERON:0002101 ! limb name: limb def: "A paired appendage that is evolved from a paired fin. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the girdle and its parts." [Wikipedia:Limb, UBERONREF:0000003] subset: uberon_slim synonym: "limb sensu vertebrata" EXACT [MAT:0000090] synonym: "tetrapod limb" EXACT [] synonym: "pentadactyl limb" EXACT [] synonym: "free limb" EXACT [FMA:24875] synonym: "flipper" NARROW SENSU [] synonym: "extremity" RELATED [] synonym: "extremities" RELATED PLURAL [] xref: EHDAA:1697 ! limb xref: EHDAA:8273 ! limb xref: FMA:24875 ! Free limb xref: GAID:36 ! extremity xref: galen:Extremity xref: VHOG:0000336 ! limb xref: MA:0000007 ! limb xref: MAT:0000090 ! limb sensu vertebrata xref: MIAA:0000090 ! limb sensu vertebrata xref: XAO:0003027 ! limb xref: ncithesaurus:Limb ! Limb xref: EFO:0000876 ! vertebrate limb xref: OpenCyc:Mx4rvn1uSZwpEbGdrcN5Y29ycA ! limb xref: EHDAA2:0003172 ! limb xref: EMAPA:16405 ! limb xref: AAO:0010336 ! limb xref: AEO:0000172 ! limb is_a: UBERON:0004708 ! limb/fin relationship: develops_from UBERON:0004347 ! limb bud relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: confers_advantage_in ENVO:00002009 ! terrestrial habitat xref: AAO:0010336 ! limb xref: SCTID:243996003 ! Entire limb xref: VSAO:0000121 ! limb property_value: external_definition "Organism subdivision that has as its parts the jointed appendages used for locomotion and manipulation.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010336", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000336", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0015385 [Term] id: UBERON:0002102 ! forelimb name: forelimb def: "A (free) limb that is connected to a pectoral girdle. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pectoral girdle and its parts." [Wikipedia:Forelimb, UBERONREF:0000003] comment: AO notes: note that this corresponds to FMA:'free upper limb' (a limb segment), NOT FMA:'upper limb'. Both MA and FMA consider shoulder (and shoulder bones) part of upper limb. Usage notes: Note distinction between arm and forelimb. hand is part of forelimb, but not part of arm subset: uberon_slim synonym: "pectoral limb" EXACT [] synonym: "pectoral flipper" NARROW SENSU [] synonym: "anteriormost limb" EXACT [] synonym: "fore limb" EXACT [] synonym: "foreleg" RELATED [] synonym: "forelimb" EXACT [] synonym: "superior member" EXACT [] synonym: "upper extremity" EXACT [] synonym: "upper limb" EXACT [] synonym: "free upper limb" EXACT [FMA:24878, UBERONREF:0000003] synonym: "free part of upper limb" EXACT [FMA:24878] synonym: "membrum superius" EXACT LATIN [FMA:TA, FMA:7183] xref: AAO:0000205 ! forelimb xref: EFO:0000882 ! forelimb xref: EHDAA:6208 ! upper limb xref: FMA:24878 ! free upper limb xref: GAID:1215 ! forelimb xref: GAID:51 ! upper extremity xref: VHOG:0000338 ! forelimb xref: MA:0000025 ! forelimb xref: MAT:0000394 ! forelimb xref: MIAA:0000394 ! forelimb xref: XAO:0003030 ! forelimb xref: ncithesaurus:Upper_Extremity ! Upper Extremity xref: BTO:0001729 ! forelimb xref: galen:UpperExtremity ! upper extremity xref: EHDAA2:0002133 ! upper limb xref: EMAPA:17412 ! forelimb xref: MESH:A13.395 ! forelimb xref: EV:0100014 ! upper limb xref: VSAO:0000148 ! forelimb intersection_of: UBERON:0002101 ! limb intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: connected_to UBERON:0001421 ! pectoral girdle region relationship: anterior_to UBERON:0002103 ! hindlimb relationship: part_of UBERON:0000153 ! anterior region of body relationship: develops_from UBERON:0005417 ! forelimb bud relationship: spatially_disjoint_from UBERON:0002103 ! hindlimb xref: SCTID:182245002 ! Entire upper limb property_value: external_definition "Upper limb, which connects the manus with the pectoral girdle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000205", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C1140618 xref: CALOHA:TS-2214 ! Upper limb [Term] id: UBERON:0002103 ! hindlimb name: hindlimb def: "A (free) limb that is connected to a pelvic girdle region. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pelvic girdle and its parts." [Wikipedia:Lower_limb, Wikipedia:Hindlimb, UBERONREF:0000003] comment: AO notes: note that this corresponds to FMA:'free lower limb' (a limb segment), NOT 'lower limb'. Both MA and FMA consider shoulder (and shoulder bones) part of upper limb. Note that AAO class probably refers to skeleton subset: uberon_slim synonym: "free lower limb" EXACT [UBERONREF:0000003, FMA:24879] synonym: "pelvic appendage" RELATED [] synonym: "hind limb" EXACT [] synonym: "hindlimb" EXACT [] synonym: "inferior member" EXACT [] synonym: "lower extremity" RELATED [] synonym: "lower limb" EXACT [] xref: AAO:0000219 ! hind_limb xref: EFO:0000883 ! hindlimb xref: EHDAA:6094 ! lower limb xref: FMA:24879 ! free lower limb xref: GAID:1221 ! hindlimb xref: GAID:38 ! lower extremity xref: VHOG:0000337 ! hindlimb xref: MA:0000026 ! hindlimb xref: MAT:0000395 ! hindlimb xref: MIAA:0000395 ! hindlimb xref: XAO:0003031 ! hind limb xref: ncithesaurus:Lower_Extremity ! Lower Extremity xref: BTO:0002345 ! hindlimb xref: galen:LowerExtremity ! lower extremity xref: EHDAA2:0001033 ! lower limb xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Gray1239.png/200px-Gray1239.png xref: EMAPA:17458 ! hindlimb xref: MESH:A13.473 ! hindlimb xref: EV:0100015 ! lower limb xref: VSAO:0000150 ! hindlimb intersection_of: UBERON:0002101 ! limb intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: connected_to UBERON:0001271 ! pelvic girdle region relationship: part_of UBERON:0000154 ! posterior region of body relationship: develops_from UBERON:0005418 ! hindlimb bud synonym: "membrum inferius" EXACT LATIN [FMA:TA, FMA:7184] xref: SCTID:182281004 ! Entire lower limb xref: ncithesaurus:Hind_Limb ! Hind Limb synonym: "membrum inferius" RELATED LATIN [Wikipedia:Lower_limb] xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray1239.png property_value: external_definition "Lower limb, which connects the pes with the pelvic girdle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000219", date_retrieved="2012-06-20", source="AAO:LAP"} synonym: "free part of lower limb" RELATED [FMA:24879] synonym: "hind-limb" EXACT [VSAO:0000150] property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000337", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "crural" xsd:string xref: UMLS:C1522391 xref: UMLS:C0023216 xref: CALOHA:TS-2215 ! Lower limb [Term] id: UBERON:0000376 name: hindlimb stylopod def: "In humans the thigh is the area between the pelvis and the knee. Anatomically, it is part of the lower limb. The single bone in the thigh is called the femur. This bone is very thick and strong (due to the high proportion of cortical bone), and forms a ball and socket joint at the hip, and a condylar joint at the knee. [WP,unvetted]." [Wikipedia:Thigh] comment: Naming conventions for pod terms under discussion within phenoscape group. TODO - add distinct term for skeleton and place AAO class here synonym: "proximal segment of free lower limb" EXACT [FMA:24967] synonym: "thigh" EXACT [] synonym: "upper leg" EXACT [MA:0000052] synonym: "stylopod of lower limb" EXACT [] synonym: "hind limb stylopod" EXACT [OBOL:automatic] synonym: "hindlimb stylopod" EXACT [OBOL:automatic] synonym: "hindlimb stylopodium" EXACT [OBOL:automatic] synonym: "inferior member stylopod" EXACT [OBOL:automatic] synonym: "lower extremity stylopod" EXACT [OBOL:automatic] synonym: "stylopod of hind limb" EXACT [OBOL:automatic] synonym: "stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "stylopod of inferior member" EXACT [OBOL:automatic] synonym: "stylopod of lower extremity" EXACT [OBOL:automatic] synonym: "hind propodium" EXACT [AAO:0000887] synonym: "hindlimb propodium" EXACT [AAO:0000887] xref: MA:0000052 ! upper leg xref: BTO:0001376 xref: FMA:24967 ! Thigh xref: ncithesaurus:Thigh ! Thigh xref: EFO:0001943 ! thigh xref: GAID:50 ! thigh xref: EHDAA:5171 ! upper leg xref: EHDAA:6200 ! upper leg xref: galen:Thigh ! thigh xref: OpenCyc:Mx4rvVjN7JwpEbGdrcN5Y29ycA ! thigh xref: EHDAA2:0002130 ! upper leg xref: VHOG:0000349 ! hindlimb stylopodium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4b/Gray1238.png/200px-Gray1238.png xref: EMAPA:17499 ! upper leg xref: MESH:A01.378.610.750 ! thigh xref: AAO:0000887 ! hind propodium is_a: UBERON:0002472 ! stylopod intersection_of: UBERON:0002472 ! stylopod intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0000978 {source="MA"} ! leg xref: SCTID:302544002 ! Entire thigh synonym: "femur" RELATED LATIN [Wikipedia:Thigh] xref: http://upload.wikimedia.org/wikipedia/commons/4/4b/Gray1238.png property_value: external_definition "Segment of the forearm corresponding to the humerus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000199", date_retrieved="2012-06-20", source="AAO:LAP"} synonym: "hind limb stylopodium" EXACT [VHOG:0000349] property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000349", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0039866 [Term] id: UBERON:0003822 name: forelimb stylopod def: "A stylopod that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing stylopod" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] comment: WP states: anatomical usage, the term arm refers specifically to the segment between the shoulder and the elbow, while the segment between the elbow and wrist is the forearm. However, in common, literary, and historical usage, arm refers to the entire upper limb from shoulder to wrist. FMA uses the term Arm for this class, so we place it here. // comment: todo - check fore propodium in AAO // Naming conventions for pod terms under discussion within phenoscape group. TODO - add distinct term for skeleton and place AAO class here synonym: "proximal segment of free upper limb" EXACT [] synonym: "stylopod of arm" EXACT [] synonym: "stylopod of forelimb" EXACT [] synonym: "upper arm" EXACT [MA:0000035] synonym: "forelimb stylopodium" EXACT [OBOL:automatic] synonym: "forelimb stylopodial element" EXACT [MA:th] synonym: "brachial region" EXACT [] synonym: "proximal segment of free upper limb" EXACT [] synonym: "arm" RELATED INCONSISTENT [FMA:24890] synonym: "regio brachialis" EXACT LATIN [FMA:TA, FMA:24890] synonym: "fore propodium" EXACT [AAO:0000199] synonym: "forelimb propodium" EXACT [] synonym: "brachium" EXACT [VSAO:0005057] xref: MA:0000035 ! upper arm xref: EHDAA:4186 ! upper arm xref: EHDAA:6234 ! upper arm xref: OpenCyc:Mx4rvVj0Z5wpEbGdrcN5Y29ycA ! upper arm xref: EHDAA2:0002112 ! upper arm xref: VHOG:0000343 ! forelimb stylopodium xref: FMA:24890 ! Arm xref: galen:Arm xref: ncithesaurus:Arm ! Arm xref: EMAPA:17424 ! upper arm xref: MESH:A01.378.800.075 ! arm (also: UBERON:0001460 'arm') xref: AAO:0000199 ! fore propodium intersection_of: UBERON:0002472 ! stylopod intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0001460 {source="MA"} ! arm xref: SCTID:302538001 ! Entire upper arm xref: VSAO:0005057 ! brachium property_value: external_definition "Segment of the hindleg corresponding to the humerus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000887", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000343", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0446516 [Term] id: UBERON:0002386 name: forelimb zeugopod def: "The middle limb segment of the pectoral free limb, between the autopod and stylopod segments. Includes as parts the forelimb zeugopodial skeleton, which includes as parts the radius and ulna, or their cartilage precursors, or evolutionary variants." [PHENOSCAPE:curators, Wikipedia:Forearm] synonym: "wing zeugopod" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] comment: Naming conventions for pod terms under discussion within phenoscape group. TODO - add distinct term for skeleton and place AAO class here subset: uberon_slim synonym: "antibrachium" EXACT [] synonym: "antebrachium" EXACT [Wikipedia:Forearm] synonym: "antebrachial region" EXACT [] synonym: "zeugopod of arm" EXACT [] synonym: "zeugopod of forelimb" EXACT [] synonym: "lower arm" EXACT [] synonym: "forelimb zeugopodium" EXACT [] synonym: "intermediate segment of free upper limb" EXACT [] synonym: "lower segment of arm" EXACT [] synonym: "forearm" EXACT [] synonym: "forelimb zygopod" EXACT [] synonym: "arm middle limb segment" EXACT [OBOL:automatic] synonym: "arm zeugopod" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "brachial region zeugopod" EXACT [OBOL:automatic] synonym: "middle limb segment of forelimb" EXACT [UBERON:cjm] synonym: "middle limb segment of arm" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "fore epipodium" RELATED [] synonym: "forelimb epipodium" EXACT [] synonym: "antebrachium" EXACT [VSAO:0005058] xref: EHDAA:4172 ! forearm xref: EHDAA:6218 ! forearm xref: FMA:9663 ! Forearm xref: GAID:55 ! forearm xref: galen:Forearm xref: MA:0000034 ! lower arm xref: OpenCyc:Mx4rvVjnmpwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvVjnmpwpEbGdrcN5Y29ycA ! forearm xref: EHDAA2:0000553 ! forearm xref: VHOG:0000341 ! forelimb zeugopodium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/50/Forearm_labeled.png/200px-Forearm_labeled.png xref: ncithesaurus:Forearm ! Forearm xref: BTO:0001447 ! forearm xref: EMAPA:17417 ! forearm xref: MESH:A01.378.800.585 ! forearm xref: EFO:0003053 ! forearm intersection_of: UBERON:0002471 ! zeugopod intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0001460 {source="MA"} ! arm synonym: "regio antebrachialis" EXACT LATIN [FMA:TA, FMA:9663] xref: SCTID:362741001 ! Entire forearm xref: VSAO:0005058 ! antebrachium synonym: "antebrachium" RELATED LATIN [Wikipedia:Forearm] xref: http://upload.wikimedia.org/wikipedia/commons/3/3b/Veins.jpg property_value: external_definition "The middle forelimb region. [Evolution, Fourth_Edition_(2006)_Boston_etc.:_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.321, see_Kardong_KV][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000341", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000341", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0016536 xref: CALOHA:TS-2205 ! Forearm [Term] id: UBERON:0003823 name: hindlimb zeugopod def: "The middle limb segment of the pelvic free limb, between the autopod and stylopod segments. Includes as parts the hindlimb zeugopodial skeleton, which includes as parts the tibia and fibula, or their cartilage precursors, or evolutionary variants." [PHENOSCAPE:curators, Wikipedia:Forearm] comment: note that FMA:24979 denotes the middle segment (zeugopod), its placement here is correct. See obo-anatomy archives for discussion // Naming conventions for pod terms under discussion within phenoscape group. TODO - add distinct term for skeleton and place AAO class here synonym: "crus of hindlimb" EXACT [] synonym: "crus" EXACT [VSAO:0005060] synonym: "shank" EXACT [VSAO:0005060] synonym: "lower leg" EXACT [] synonym: "calf" NARROW [] synonym: "hindlimb zygopod" EXACT [] synonym: "hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "hind limb zeugopod" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "hindlimb zeugopodium" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb" EXACT [UBERON:cjm] synonym: "zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb" EXACT [FMA:24979] synonym: "posterior part of leg" EXACT [FMA:24984] synonym: "calf of leg" EXACT [FMA:24984] synonym: "posterior curral region" EXACT [FMA:24984] synonym: "posterior leg region" EXACT [FMA:24984] synonym: "posterior region of leg" EXACT [FMA:24984] synonym: "sural region" EXACT [FMA:24984] synonym: "leg" RELATED INCONSISTENT [FMA:24979, MESH:A01.378.610.500] synonym: "hind epipodium" RELATED INCONSISTENT [] synonym: "hindlimb epipodium" EXACT [] xref: MA:0000051 ! lower leg xref: EHDAA:5165 ! lower leg xref: EHDAA:6190 ! lower leg xref: OpenCyc:Mx4rvczZBpwpEbGdrcN5Y29ycA ! lower leg xref: FMA:24984 ! Posterior part of leg xref: EHDAA2:0001030 ! lower leg xref: VHOG:0000348 ! hindlimb zeugopodium xref: FMA:24979 ! Leg xref: galen:Leg xref: ncithesaurus:Leg ! Leg xref: MESH:A01.378.610.500 ! leg xref: EMAPA:17496 ! lower leg xref: EFO:0003051 ! calf intersection_of: UBERON:0002471 ! zeugopod intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0000978 {source="MA"} ! leg synonym: "sura" EXACT LATIN [FMA:TA, FMA:24984] synonym: "regio cruris posterior" EXACT LATIN [FMA:TA, FMA:24984] synonym: "regio surae" EXACT LATIN [FMA:TA, FMA:24984] xref: SCTID:244015008 ! Entire calf of leg xref: VSAO:0005060 ! shank synonym: "hindlimb zeudopodium" EXACT [VHOG:0000348] synonym: "hind limb zeudopodium" EXACT [VHOG:0000348] property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0000348", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "sural" xsd:string xref: UMLS:C1140621 [Term] id: UBERON:0002472 ! stylopod name: stylopod def: "The proximal free limb segment. Includes as parts the stylopod skeleton." [] comment: Naming conventions for pod terms under discussion within phenoscape group subset: uberon_slim synonym: "proximal part of limb" BROAD [] synonym: "stylopodium" EXACT [] synonym: "stylopodial limb segment" EXACT [MA:th] synonym: "propodium" EXACT [MA:th] synonym: "proximal free limb segment" EXACT [FMA:83014] xref: EFO:0000879 ! stylopod xref: MA:0002717 ! stylopod xref: MAT:0000093 ! stylopod xref: MIAA:0000093 ! stylopod xref: FMA:83014 ! proximal free limb segment is_a: UBERON:0002529 ! limb segment relationship: part_of UBERON:0002101 ! limb relationship: proximal_to UBERON:0002471 ! zeugopod synonym: "proximal segment of free limb" RELATED [FMA:83014] property_value: has_relational_adjective "stylopodial" xsd:string [Term] id: UBERON:0002471 ! zeugopod name: zeugopod def: "The middle free limb segment, between the autopod and stylopod segments. Includes as parts the zeugopodial skeleton. Examples: There are two types of zeugopod: forelimb zeugopod (aka forearm), hindlimb zeugopod (aka crus)." [PHENOSCAPE:curators] comment: There exists some controversy about which podial segments are present in some fishes, e.g. if the autopod is not newly evolved in tetrapods, there is a question as to which segments are actually present in basal vertebrate taxa.[PHENOSCAPE:curators] subset: uberon_slim synonym: "middle part of limb" BROAD [] synonym: "middle limb segment" EXACT [] synonym: "zygopod" EXACT [] synonym: "zygopodium" EXACT [] synonym: "zeugopodium" EXACT [] synonym: "zeugopod limb segment" EXACT [MA:th] synonym: "zeugopodial limb segment" EXACT [MA:th] synonym: "epipodium" EXACT [MA:th] synonym: "middle free limb segment" EXACT [FMA:83016] xref: EFO:0000878 ! zeugopod xref: MA:0002716 ! zeugopod xref: MAT:0000092 ! zeugopod xref: MIAA:0000092 ! zeugopod xref: FMA:83016 ! middle free limb segment is_a: UBERON:0002529 ! limb segment relationship: distal_to UBERON:0002472 ! stylopod relationship: proximal_to UBERON:0002470 ! autopod region synonym: "middle segment of free limb" RELATED [FMA:83016] property_value: has_relational_adjective "zeugopodial" xsd:string [Term] id: UBERON:0002104 name: visual system def: "." [Wikipedia:Visual_system] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "visual organ system" EXACT [] xref: AAO:0000632 ! visual_system xref: FMA:7191 ! Visual system xref: MA:0002444 ! visual system xref: OpenCyc:Mx4rvViCtpwpEbGdrcN5Y29ycA xref: TAO:0001127 ! visual system xref: ZFA:0001127 ! visual system xref: XAO:0003198 ! visual system xref: NIF_GrossAnatomy:FMAID_7191 xref: ncithesaurus:Visual_System ! Visual System xref: OpenCyc:Mx4rvViCtpwpEbGdrcN5Y29ycA ! visual system is_a: UBERON:0001032 ! sense organ system relationship: spatially_disjoint_from UBERON:0002105 ! auditory system relationship: capable_of GO:0007601 ! visual perception xref: SCTID:281831001 ! Entire visual system property_value: external_definition "The sensory system used for sight.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000632", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C0587900 [Term] id: UBERON:0002106 name: spleen def: "Organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system. In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron. It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells." [Wikipedia:Spleen] comment: Taxon notes: Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96) [PMID:20959416] subset: uberon_slim subset: vertebrate_core xref: BTO:0001281 xref: EFO:0000869 ! spleen xref: FMA:7196 ! Spleen xref: GAID:1289 ! spleen xref: VHOG:0000120 ! spleen xref: MA:0000141 ! spleen xref: MAT:0000085 ! spleen xref: MIAA:0000085 ! spleen xref: OpenCyc:Mx4rvVjgw5wpEbGdrcN5Y29ycA xref: TAO:0000436 ! spleen xref: XAO:0000328 ! spleen xref: ZFA:0000436 ! spleen xref: ncithesaurus:Spleen ! Spleen xref: galen:Spleen ! spleen xref: OpenCyc:Mx4rvVjgw5wpEbGdrcN5Y29ycA ! spleen xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Illu_spleen.jpg/200px-Illu_spleen.jpg xref: EMAPA:18767 ! spleen xref: MESH:A15.382.520.604.713 ! spleen xref: EV:0100055 ! spleen is_a: UBERON:0002075 ! viscus relationship: develops_from UBERON:0006293 ! spleen primordium relationship: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0002405 ! immune system relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: only_in_taxon NCBITaxon:7776 {source="multiple sources - true spleen appear in jawed vertebrates"} ! Gnathostomata xref: AAO:0010395 ! spleen xref: SCTID:181279003 ! Entire spleen subset: organ_slim synonym: "lien" RELATED LATIN [Wikipedia:Spleen] xref: http://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg property_value: external_definition "An organ involved in red blood cell filtration and immune response.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010395", date_retrieved="2012-06-20", source="AAO:BMZ"} property_value: homology_notes "With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0000120", ontology="VHOG", source="ISBN:978-0781765190 Paul WE\, Fundamental Immunology (2008) p.94", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "splenic" xsd:string property_value: has_relational_adjective "lienal" xsd:string xref: UMLS:C0037993 [Term] id: UBERON:0006293 ! spleen primordium alt_id: UBERON:0009750 name: spleen primordium def: "A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]." [ISBN:0123747295, MP:0011263] comment: AO notes: check difference between splenic and spleen in EMAPA; note that in EHDAA2 the class 'spleen' refers to the mesenchyme synonym: "left spleen primordium" NARROW [XAO:0000326] synonym: "splenic primordium" EXACT [EHDAA2:0001904] synonym: "spleen mesenchyme" EXACT [MP:0011263] synonym: "splenic mesenchyme" EXACT [UBERON:cjm] xref: EHDAA2:0001904 ! spleen xref: EMAPA:18659 ! splenic primordium xref: EHDAA:3003 ! splenic primordium xref: EMAPA:18535 ! spleen primordium xref: XAO:0000326 ! left spleen primordium is_a: UBERON:0001048 {source="XAO"} ! primordium is_a: UBERON:0003104 ! mesenchyme relationship: develops_from UBERON:0004872 {source="XAO"} ! splanchnic layer of lateral plate mesoderm relationship: part_of UBERON:0005602 {source="EHDAA2-modified"} ! dorsal mesogastrium [Term] id: UBERON:0013119 name: haemal node def: "A lymphoid organ found in various mammals and some birds." [Wikipedia:Haemal_nodes] comment: Hemal nodes are characterized by the presence of large numbers of erythrocytes. Lymph nodes (see below) and hemal nodes share some similarities of structure, but really are fundamentally different organs both qualitatively and quantitatively. Both lymph and hemal nodes contain diffuse lymphatic tissue, and in most cases have nodular tissue in the form of germinal centers, as well. Like the lymph node, the hemal node has a cortex and a medulla, and germinal centers are frequently seen. There's a distinct capsule, and hemal nodes are served at the hilus by an afferent arteriole. [http://www.vetmed.vt.edu/education/curriculum/vm8054/labs/lab13/lab13.htm] synonym: "hemal node" EXACT [] is_a: UBERON:0004177 ! hemopoietic organ relationship: part_of UBERON:0002405 ! immune system relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: develops_from UBERON:0001637 ! artery [Term] id: UBERON:0002108 name: small intestine def: "Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]." [Wikipedia:Small_intestine] subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "anterior intestine" RELATED [] synonym: "mid intestine" RELATED [] synonym: "small bowel" EXACT [] synonym: "small intestine" EXACT [] synonym: "intestinum tenue" RELATED [BTO:0000651] xref: BTO:0000651 xref: EFO:0000841 ! small intestine xref: FMA:7200 ! Small intestine xref: GAID:313 ! small intestine xref: VHOG:0000055 ! small intestine xref: MA:0000337 ! small intestine xref: MAT:0000047 ! small intestine xref: MIAA:0000047 ! small intestine xref: ncithesaurus:Small_Intestine xref: OpenCyc:Mx4rvVjlIJwpEbGdrcN5Y29ycA xref: TAO:0001323 ! mid intestine xref: XAO:0000130 ! small intestine xref: ZFA:0001323 ! mid intestine xref: galen:SmallIntestine ! small intestine xref: OpenCyc:Mx4rvVjlIJwpEbGdrcN5Y29ycA ! small intestine xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/82/Stomach_colon_rectum_diagram.svg/200px-Stomach_colon_rectum_diagram.svg.png xref: MESH:A03.492.411.620 ! small intestine xref: EV:0100072 ! small intestine is_a: UBERON:0000062 ! organ is_a: UBERON:0004921 {source="cjm", order="2"} ! subdivision of digestive tract relationship: part_of UBERON:0000160 ! intestine xref: AAO:0010397 ! small intestine xref: SCTID:181250005 ! Entire small intestine subset: organ_slim synonym: "intestinum tenue" RELATED LATIN [Wikipedia:Small_intestine] xref: http://upload.wikimedia.org/wikipedia/commons/8/82/Stomach_colon_rectum_diagram.svg property_value: external_definition "The terminal region of the mid intestine is comprised of specialized enterocytes that appear to play a role in mucosal immunity. Wallace et al, 2005.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001323", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "Intestinal surface area also is increased in amphibians and reptiles by internal folds and occasionally by a few villi. The intestine can be divided into a small intestine and a slightly wider large intestine.[well established][VHOG]" xsd:string {external_class="VHOG:0000055", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.566", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0021852 [Term] id: UBERON:0002110 name: gallbladder def: "a small organ that aids digestion and stores bile produced by the liver[WP]. Organ with organ cavity which is continuous proximally with the cystic duct and distally terminates in the fundus of the gallbladder[FMA]." [Wikipedia:Gallbladder, FMA:7202] comment: Rats do not have a gallbladder, but produce bile. The bile flows directly from the liver through the (hepatic) bile duct into the small intestine (Hebel and Stromberg, 1988) subset: uberon_slim subset: vertebrate_core synonym: "gall bladder" EXACT [] xref: BTO:0000493 xref: EFO:0000853 ! gall bladder xref: EHDAA:8062 ! gall bladder xref: FMA:7202 ! Gallbladder xref: galen:Gallbladder xref: VHOG:0000221 ! gall bladder xref: MA:0000356 ! gall bladder xref: MAT:0000072 ! gall bladder xref: MIAA:0000072 ! gall bladder xref: ncithesaurus:Gallbladder xref: OpenCyc:Mx4rvVkGr5wpEbGdrcN5Y29ycA xref: TAO:0000208 ! gall bladder xref: XAO:0000135 ! gall bladder xref: ZFA:0000208 ! gall bladder xref: OpenCyc:Mx4rvVkGr5wpEbGdrcN5Y29ycA ! gall bladder xref: EHDAA2:0000699 ! gall bladder xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f4/Abdomal_organs.svg/200px-Abdomal_organs.svg.png xref: EMAPA:17202 ! gall bladder xref: MESH:A03.159.439 ! gallbladder xref: EV:0100090 ! gall bladder is_a: UBERON:0002075 ! viscus relationship: part_of UBERON:0000916 ! abdomen relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: develops_from UBERON:0004912 ! biliary bud relationship: part_of UBERON:0001173 ! biliary tree relationship: never_in_taxon NCBITaxon:10114 {source="ISBN:9780120749034"} ! Rattus relationship: develops_from UBERON:0006242 {evidence="definitional"} ! gall bladder primordium xref: AAO:0010114 ! gall bladder xref: SCTID:181269000 ! Entire gallbladder subset: organ_slim synonym: "vesica fellea; vesica biliaris" RELATED LATIN [Wikipedia:Gallbladder] xref: http://upload.wikimedia.org/wikipedia/commons/3/3f/Illu_pancrease.svg property_value: external_definition "Organ attached to the liver which stores bile and empties into the duodenum via the bile duct as needed for digestion.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010114", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: axiom_lost_from_external_ontology "relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010114", date_retrieved="2012-06-20"} property_value: external_definition "Membranous muscular sac in which the bile from the liver remains stored until it is required. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000221", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The presence of a gallbladder appears to be a primitive trait. It is found in most fish and all adult reptiles and amphibians and has been well conserved in mammals, for the most part.[well established][VHOG]" xsd:string {external_class="VHOG:0000221", ontology="VHOG", source="DOI:10.1002/(SICI)1097-0029(19970915)38:6<571::AID-JEMT3>3.0.CO;2-I Oldham-Ott CK\, Gilloteaux J\, Comparative morphology of the gallbladder and biliary tract in vertebrates: Variation in structure\, homology in function and gallstones. Microscopy research and technique (1997)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0016976 [Term] id: UBERON:0002111 name: artery smooth muscle tissue def: "A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "artery smooth muscle" EXACT [] synonym: "artery smooth muscle tissue" EXACT [] synonym: "arterial smooth muscle" EXACT [BTO:0000087] synonym: "smooth muscle of artery" EXACT [FMA:72024] xref: BTO:0000087 xref: FMA:72024 ! smooth muscle of artery xref: MA:0000708 ! artery smooth muscle xref: ncithesaurus:Artery_Smooth_Muscle_Tissue ! Artery Smooth Muscle Tissue is_a: UBERON:0001135 {source="FMA"} ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001637 ! artery xref: UMLS:C1706851 [Term] id: UBERON:0002112 name: smooth muscle of esophagus def: "A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "esophagus smooth muscle" EXACT [] synonym: "oesophagus smooth muscle" RELATED [] synonym: "esophagus involuntary muscle" EXACT [OBOL:automatic] synonym: "esophagus non-striated muscle" EXACT [OBOL:automatic] synonym: "esophagus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gullet involuntary muscle" EXACT [OBOL:automatic] synonym: "gullet non-striated muscle" EXACT [OBOL:automatic] synonym: "gullet smooth muscle" EXACT [OBOL:automatic] synonym: "gullet smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of esophagus" EXACT [OBOL:automatic] synonym: "involuntary muscle of gullet" EXACT [OBOL:automatic] synonym: "involuntary muscle of oesophagus" EXACT [OBOL:automatic] synonym: "non-striated muscle of esophagus" EXACT [OBOL:automatic] synonym: "non-striated muscle of gullet" EXACT [OBOL:automatic] synonym: "non-striated muscle of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus involuntary muscle" EXACT [OBOL:automatic] synonym: "oesophagus non-striated muscle" EXACT [OBOL:automatic] synonym: "oesophagus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of gullet" EXACT [OBOL:automatic] synonym: "smooth muscle of oesophagus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of esophagus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gullet" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of oesophagus" EXACT [OBOL:automatic] xref: FMA:72025 ! Smooth muscle of esophagus xref: MA:0001573 ! esophagus smooth muscle is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0003832 ! esophagus muscle [Term] id: UBERON:0002113 name: kidney def: "A paired organ which has the production of urine as its primary function." [Wikipedia:Kidney] subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "reniculate kidney" NARROW SENSU [Wikipedia:Reniculate_kidney] xref: AAO:0000250 ! kidney xref: BTO:0000671 xref: EFO:0000929 ! kidney xref: FMA:7203 ! Kidney xref: GAID:423 ! kidney xref: galen:Kidney xref: MA:0000368 ! kidney xref: MAT:0000119 ! kidney xref: MIAA:0000119 ! kidney xref: ncithesaurus:Kidney xref: OpenCyc:Mx4rvVjlYpwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvVjlYpwpEbGdrcN5Y29ycA ! kidney xref: XAO:0003267 ! kidney xref: MESH:A05.810.453 ! kidney xref: EV:0100096 ! kidney is_a: UBERON:0000489 ! cavitated compound organ relationship: part_of UBERON:0011143 {source="FMA"} ! upper urinary tract relationship: part_of UBERON:0000916 ! abdomen relationship: spatially_disjoint_from UBERON:0000160 ! intestine relationship: develops_from UBERON:0005095 ! kidney rudiment relationship: develops_from UBERON:0003918 {evidence="definitional"} ! kidney mesenchyme relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: SCTID:181414000 ! Entire kidney subset: organ_slim property_value: external_definition "One of either of a pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000250", date_retrieved="2012-06-20", source="AAO:BJB"} relationship: in_lateral_side_of UBERON:0000468 ! multi-cellular organism property_value: has_relational_adjective "renal" xsd:string xref: UMLS:C0022646 [Term] id: UBERON:0012650 ! gastroduodenal junction name: gastroduodenal junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000945 ! stomach intersection_of: connects UBERON:0002114 ! duodenum relationship: part_of UBERON:0000945 ! stomach xref: FMA:17046 ! gastroduodenal junction xref: SCTID:264014000 ! Gastroduodenal junction [Term] id: UBERON:0002114 name: duodenum def: "The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one)." [ISBN:0815318960, Wikipedia:Duodenum] subset: uberon_slim subset: vertebrate_core synonym: "proximal intestine" RELATED [BTO:0000365] synonym: "upper intestine" RELATED [BTO:0000365] xref: BTO:0000365 xref: EFO:0000851 ! duodenum xref: FMA:7206 ! Duodenum xref: GAID:284 ! duodenum xref: galen:Duodenum xref: VHOG:0000052 ! duodenum xref: MA:0000338 ! duodenum xref: MAT:0000044 ! duodenum xref: MIAA:0000044 ! duodenum xref: ncithesaurus:Duodenum xref: OpenCyc:Mx4rv4LJDpwpEbGdrcN5Y29ycA xref: XAO:0000236 ! duodenum xref: OpenCyc:Mx4rv4LJDpwpEbGdrcN5Y29ycA ! duodenum xref: EMAPA:18852 ! duodenum of gut xref: MESH:A03.492.411.620.270 ! duodenum xref: EV:0100073 ! duodenum is_a: UBERON:0004921 {source="cjm", order="3"} ! subdivision of digestive tract relationship: part_of UBERON:0002108 ! small intestine relationship: proximal_part_of UBERON:0002108 ! small intestine relationship: dubious_for_taxon NCBITaxon:7955 {source="ZFA:0000348"} ! Danio rerio relationship: continuous_with UBERON:0001166 ! pylorus xref: AAO:0010402 ! duodenum xref: SCTID:181247007 ! Entire duodenum xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/Tractus_intestinalis_duodenum.svg property_value: external_definition "The fixed portion of the small intestine deeply lodged in the posterior wall of the abdomen and extending from the pylorus to the beginning of the jejunum. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000052", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "duodenal" xsd:string property_value: taxon_notes "In fish, the divisions of the small intestine are not as clear, and the terms anterior intestine or proximal intestine may be used instead of duodenum." xsd:string {scope="NCBITaxon:32443", source="http://en.wikipedia.org/wiki/Duodenum"} property_value: taxon_notes "In humans, the duodenum is a hollow jointed tube about 10–15 inches (25–38 centimetres) long connecting the stomach to the jejunum. It begins with the duodenal bulb and ends at the ligament of Treitz." xsd:string {scope="NCBITaxon:9606", source="http://en.wikipedia.org/wiki/Duodenum"} xref: UMLS:C0013303 [Term] id: UBERON:0002115 name: jejunum def: "The jejunum is the middle section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms middle intestine or mid-gut may be used instead of jejunum. [WP,unvetted]." [Wikipedia:Jejunum] comment: TODO consider ZFA:0001323 mid intestine, see also small intestine subset: uberon_slim synonym: "intestinum jejunum" RELATED [BTO:0000657] synonym: "middle intestine" RELATED [BTO:0000657] xref: BTO:0000657 xref: FMA:7207 ! Jejunum xref: GAID:318 ! jejunum xref: galen:Jejunum xref: VHOG:0000053 ! jejunum xref: MA:0000340 ! jejunum xref: MAT:0000045 ! jejunum xref: MIAA:0000045 ! jejunum xref: ncithesaurus:Jejunum xref: EFO:0001333 ! jejunum xref: OpenCyc:Mx4rwATkPJwpEbGdrcN5Y29ycA ! jejunum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3d/Illu_small_intestine.jpg/200px-Illu_small_intestine.jpg xref: EMAPA:18666 ! jejunum of midgut xref: EMAPA:18932 ! jejunum of gut xref: MESH:A03.492.411.620.625 ! jejunum xref: EV:0100074 ! jejunum is_a: UBERON:0004921 {source="cjm", order="3"} ! subdivision of digestive tract relationship: part_of UBERON:0002108 ! small intestine relationship: develops_from UBERON:0001045 {source="Wikipedia"} ! midgut xref: SCTID:181248002 ! Entire jejunum xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg property_value: external_definition "The first two fifth of the small intestine beyond the duodenum. It extends from the end of the duodenum to the ileum. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000053", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "jejunal" xsd:string xref: UMLS:C0022378 [Term] id: UBERON:0002116 name: ileum def: "The ileum is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms posterior intestine or distal intestine may be used instead of ileum. [WP,unvetted]." [Wikipedia:Ileum] comment: TODO consider ZFA:0000706 posterior intestine, see also colon subset: uberon_slim synonym: "distal intestine" RELATED [BTO:0000620] synonym: "intestinum ileum" RELATED [BTO:0000620] synonym: "lower intestine" RELATED [BTO:0000620] xref: BTO:0000620 xref: FMA:7208 ! Ileum xref: GAID:315 ! ileum xref: galen:Ileum xref: VHOG:0000647 ! ileum xref: MA:0000339 ! ileum xref: MAT:0000282 ! ileum xref: MIAA:0000282 ! ileum xref: ncithesaurus:Ileum xref: OpenCyc:Mx4rvdcLHZwpEbGdrcN5Y29ycA xref: XAO:0000237 ! ileum xref: EFO:0001334 ! ileum xref: OpenCyc:Mx4rvdcLHZwpEbGdrcN5Y29ycA ! ileum xref: MESH:A03.492.411.620.484 ! ileum xref: EV:0100075 ! ileum is_a: UBERON:0004921 {source="cjm", order="3"} ! subdivision of digestive tract relationship: part_of UBERON:0002108 ! small intestine xref: AAO:0010403 ! ileum xref: SCTID:181249005 ! Entire ileum xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000647", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "ileal" xsd:string xref: UMLS:C0020885 [Term] id: UBERON:0005052 ! gizzard name: gizzard def: "The muscular enlargement of the alimentary canal that has usually thick muscular walls and a tough horny lining for grinding the food and when the crop is present follows it and the proventriculus." [BTO:0000520, Wikipedia:Gizzard] comment: AO notes: BTO also includes: A thickened part of the alimentary canal in some animals (as an insect or an earthworm) that is similar in function to the crop of a bird. However, we are refering to the Aves structure here synonym: "ventriculus" RELATED [Wikipedia:Gizzard] synonym: "gastric mill" EXACT [Wikipedia:Gizzard] synonym: "gigerium" EXACT [Wikipedia:Gizzard] xref: BTO:0000520 xref: GAID:1238 ! gizzard xref: MESH:A13.853.363 ! gizzard is_a: UBERON:0000945 {source="cjm"} ! stomach relationship: part_of UBERON:0001555 ! digestive tract relationship: has_part UBERON:0008861 {source="Wikipedia"} ! pyloric gastric gland relationship: only_in_taxon NCBITaxon:8782 ! Aves xref: ncithesaurus:Gizzard ! Gizzard subset: organ_slim xref: UMLS:C1510668 [Term] id: UBERON:0011903 name: gizzard smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005052 ! gizzard xref: BTO:0000521 ! gizzard smooth muscle def: "A smooth muscle tissue that is part of a gizzard." [OBOL:automatic] [Term] id: UBERON:0011904 name: gastrolith def: "a rock held inside a gastrointestinal tract." [Wikipedia:Gastrolith] synonym: "stomach stone" RELATED [Wikipedia:Gastrolith] synonym: "gizzard stone" RELATED [Wikipedia:Gastrolith] is_a: UBERON:0000476 ! acellular anatomical structure relationship: part_of UBERON:0001007 ! digestive system [Term] id: UBERON:0012422 name: secretion of crop def: "Nutritional fluid secreted by the crop in some species[Kardong]" [ISBN10:0073040584] synonym: "crop milk" RELATED [ISBN10:0073040584] intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0007356 ! crop [Term] id: UBERON:0007356 ! crop name: crop def: "A pouched enlargement of the gullet of many birds that serves as a receptacle for food and for its preliminary maceration." [BTO:0000301, Wikipedia:Crop_(anatomy)#Birds] comment: Editor notes: we follow WP and place as part of the esophagus. Taxon notes: Aves specific structure - consider adding functional grouping class. Kardong: some cetaceans have a crop-like structure synonym: "esophageal diverticulum" BROAD [] synonym: "esophageal pouch" RELATED [] xref: BTO:0000301 ! crop is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001043 ! esophagus relationship: only_in_taxon NCBITaxon:8782 ! Aves xref: SCTID:68028003 ! Crop [Term] id: UBERON:0007357 name: proventriculus def: "The glandular or true stomach of a bird that is situated between the crop and gizzard." [BTO:0001136, Wikipedia:Proventriculus] comment: Taxon notes: consider extending to crocodilians. EMAPA has proventricular region xref: BTO:0001136 ! proventriculus xref: MESH:A13.853.710 ! proventriculus xref: GAID:1239 ! proventriculus is_a: UBERON:0011953 {source="cjm"} ! stomach glandular region relationship: only_in_taxon NCBITaxon:8782 ! Aves relationship: continuous_with UBERON:0007356 ! crop relationship: continuous_with UBERON:0005052 ! gizzard relationship: has_part UBERON:0010038 {source="Wikipedia"} ! fundic gastric gland relationship: capable_of GO:0001696 ! gastric acid secretion xref: SCTID:63897003 ! Proventriculus subset: organ_slim [Term] id: UBERON:0007366 ! ruminant stomach def: "The ruminants' stomach consists of four compartments: rumen, reticulum, omasum and abomasum. The first three compartments comprise the forestomach (proventriculus). They are lined with nonglandular membrane. The fourth compartment, the abomasum comprises the true stomach of the ruminants. It is lined with glandular mucous membrane. The rumen lies on the left of the abdominal cavity, the reticulum cranially and the omasum on the right. The abomasum lies ventrally, its proximal end lies ventral to the rumen, reticulum and omasum" [http://www.onemedicine.tuskegee.edu/DigestiveSystem/Stomach/Stomach_Ruminants.html] synonym: "plurilocular stomach" RELATED [] comment: Editor notes: Consider classifying each subdivision as 'stomach chamber' name: ruminant stomach xref: MESH:A13.869 ! ruminant stomach xref: GAID:1240 ! ruminant stomach xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Abomasum_%28PSF%29.png is_a: UBERON:0000945 ! stomach relationship: only_in_taxon NCBITaxon:9845 ! Ruminantia [Term] id: UBERON:0007358 name: abomasum def: "The fourth stomach of ruminating animals. It is also called the \"true\" stomach. It is an elongated pear-shaped sac lying on the floor of the abdomen, on the right-hand side, and roughly between the seventh and twelfth ribs. It leads to the beginning of the small intestine. (From Black's Veterinary Dictionary, 17th ed)" [MESH:A13.869.106, Wikipedia:Abomasum] synonym: "ruminant true stomach" RELATED [] synonym: "fourth stomach" RELATED [BTO:0000024] synonym: "maw" RELATED [Wikipedia:Abomasum] synonym: "rennet-bag" RELATED [Wikipedia:Abomasum] synonym: "read" RELATED [Wikipedia:Abomasum] xref: BTO:0000024 ! abomasum xref: MESH:A13.869.106 ! abomasum xref: GAID:1241 ! abomasum is_a: UBERON:0011953 ! stomach glandular region relationship: part_of UBERON:0007366 ! ruminant stomach xref: SCTID:410028001 ! Entire abomasum (also: UBERON:0007362 'omasum') xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Abomasum_%28PSF%29.png subset: organ_slim xref: ncithesaurus:Abomasum ! abomasum [Term] id: UBERON:0010154 name: inner lining mucosa of the abomasum def: "the inner mucosa of the fourth stomach chamber of a ruminant produces rennet." [Wikipedia:Rennet] synonym: "rennet" RELATED [BTO:0001168] is_a: UBERON:0000344 ! mucosa relationship: part_of UBERON:0007358 {source="BTO"} ! abomasum xref: BTO:0001168 ! rennet [Term] id: UBERON:0007359 name: ruminant forestomach def: "Any of the first three stomachs of a ruminant, i.e., the rumen, reticulum, or omasum." [BTO:0000480] comment: Development/homology notes: You will still see the statement in some texts that the parts of the forestomach are derived from the embryonic esophagus, and that's the reason why (like the esophagus) they're lined with stratified squamous epithelium. This is open to doubt. While there is no doubt that the rumen, reticulum, and omasum are all derived from the embryonic foregut, there is evidence to indicate that all three come from that an area of the foregut homologous to the part that develops into the single stomach of non-ruminants. If this is so, then the forestomach can be considered diverticula (or derivatives) of the stomach proper, not the esophagus, despite the nature of the lining -- http://www.vetmed.vt.edu/education/curriculum/vm8054/labs/lab21/Examples/exrumen.htm synonym: "forestomach" BROAD SENSU [BTO:0000480] xref: BTO:0000480 ! forestomach xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Abomasum_%28PSF%29.png is_a: UBERON:0011954 ! stomach non-glandular region relationship: part_of UBERON:0007366 ! ruminant stomach relationship: develops_from UBERON:0001041 ! foregut subset: organ_slim [Term] id: UBERON:0007361 name: ruminant reticulum def: "The second stomach of ruminants. It lies almost in the midline in the front of the abdomen, in contact with the liver and diaphragm and communicates freely with the RUMEN via the ruminoreticular orifice. The lining of the reticulum is raised into folds forming a honeycomb pattern over the surface. (From Concise Veterinary Dictionary, 1988)" [MESH:A13.869.697, Wikipedia:Reticulum_(anatomy)] synonym: "reticulum" BROAD SENSU [BTO:0000347] xref: MESH:A13.869.697 ! reticulum xref: BTO:0000347 ! reticulum xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Abomasum_%28PSF%29.png is_a: UBERON:0011954 ! stomach non-glandular region relationship: part_of UBERON:0007359 ! forestomach relationship: part_of UBERON:0007364 ! reticulorumen xref: SCTID:23703003 ! Reticulum xref: ncithesaurus:Reticulum ! reticulum [Term] id: UBERON:0007362 name: omasum def: "The third stomach of ruminants, situated on the right side of the abdomen at a higher level than the fourth stomach and between this latter and the second stomach, with both of which it communicates. From its inner surface project large numbers of leaves or folia, each of which possesses roughened surfaces. In the center of each folium is a band of muscle fibers which produces a rasping movement of the leaf when it contracts. One leaf rubs against those on either side of it, and large particles of food material are ground down between the rough surfaces, preparatory to further digestion in the succeeeding parts of the alimentary canal. (Black's Veterinary Dictionary, 17th ed)" [MESH:A13.869.524, Wikipedia:Omasum] synonym: "omasum" RELATED [MESH:A13.869.524] xref: MESH:A13.869.524 ! omasum xref: BTO:0000348 ! omasum xref: GAID:1242 ! omasum xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Abomasum_%28PSF%29.png is_a: UBERON:0011954 ! stomach non-glandular region relationship: part_of UBERON:0007359 ! forestomach relationship: part_of UBERON:0007364 ! reticulorumen xref: SCTID:410028001 ! Entire abomasum (also: UBERON:0007358 'abomasum') xref: ncithesaurus:Omasum ! omasum [Term] id: UBERON:0007365 name: rumen def: "The first stomach of ruminants. It lies on the left side of the body, occupying the whole of the left side of the abdomen and even stretching across the median plane of the body to the right side. It is capacious, divided into an upper and a lower sac, each of which has a blind sac at its posterior extremity. The rumen is lined by mucous membrane containing no digestive glands, but mucus-secreting glands are present in large numbers. Coarse, partially chewed food is stored and churned in the rumen until the animal finds circumstances convenient for rumination. When this occurs, little balls of food are regurgitated through the esophagus into the mouth, and are subjected to a second more thorough mastication, swallowed, and passed on into other parts of the compound stomach. (From Black's Veterinary Dictionary, 17th ed)." [MESH:A13.869.804, Wikipedia:Rumen] comment: Structure notes: There is no muscularis mucosae in the rumen synonym: "paunch" RELATED [BTO:0001194] xref: MESH:A13.869.804 xref: GAID:1244 ! rumen xref: BTO:0001194 ! rumen xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Abomasum_%28PSF%29.png is_a: UBERON:0011954 ! stomach non-glandular region relationship: part_of UBERON:0007359 ! forestomach relationship: part_of UBERON:0007364 ! reticulorumen xref: SCTID:45138000 ! Rumen xref: ncithesaurus:Rumen ! rumen [Term] id: UBERON:0008285 ! rumen epithelium name: rumen epithelium def: "The rumen epithelium is the tissue which lines the largest of the four fore stomachs in the ruminant animal -cows and sheep. Rumen epithelial cells are important because they are responsible for the absorption of nutrients from the rumen into the blood." [PMID:10764086, BTO:0001195] is_a: UBERON:0010040 {source="cjm"} ! stomach non-glandular epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0007365 ! rumen xref: BTO:0001195 ! rumen epithelium [Term] id: UBERON:0010228 name: ruminal fluid intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: located_in UBERON:0007365 ! rumen xref: BTO:0004789 ! ruminal fluid (also: UBERON:0010229 'ruminant esophageal groove') def: "A portion of organism substance that surrounded_by a rumen." [OBOL:automatic] [Term] id: UBERON:0010229 name: ruminant esophageal groove def: "A muscular structure at the lower end of the esophagus that, when closed, forms a tube allowing milk to go directly into the abomasum. (This prevents milk from being fermented or soured by the ruminal microorganisms)." [http://www.extension.org/pages/16468/esophageal-groove] comment: The formation of the esophageal groove is controlled by neural stimulation from suckling and milk proteins. This means milk, colostrum, and milk replacer bypass the rumen, while water enters it synonym: "esophageal groove" BROAD SENSU [] synonym: "reticular groove" BROAD SENSU [] synonym: "ruminant reticular groove" EXACT [] is_a: UBERON:0006846 ! groove relationship: develops_from UBERON:0007361 ! ruminant reticulum relationship: channel_for UBERON:0001913 ! milk relationship: channels_from UBERON:0001043 ! esophagus relationship: channels_into UBERON:0007358 ! abomasum relationship: existence_ends_during UBERON:0000113 ! post-juvenile adult stage xref: BTO:0004789 ! ruminal fluid (also: UBERON:0010228 'ruminal fluid') xref: SCTID:86149002 ! Reticular groove [Term] id: UBERON:0010153 name: rumen papilla is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0008285 ! rumen epithelium synonym: "rumen papillae" EXACT PLURAL [] [Term] id: UBERON:0007364 ! reticulorumen name: reticulorumen def: "first chamber in the alimentary canal of ruminant animals. It is composed of the rumen and reticulum. The reticulum differs from the rumen with regard to the texture of its lining. The rumen wall is covered in small finger like projections called papillae, which are flattened, approximately 0.5 cm in length and 0.3 cm wide in cattle. The reticulum is lined with ridges that form a hexagonal honeycomb pattern. The ridges are approximately 0.1 - 0.2 mm wide and are raised 0.5 cm above the reticulum wall. The hexagons in the reticulum are approximately 2-5 cm wide in cattle. Despite the differences in the texture of the lining of the two parts of the reticulorumen, it represents one functional space. Microbial fermentation degrades ingested carbohydrates in the reticulorumen to the volatile fatty acids acetate, propionate and butyrate, and proteins to short peptides, amino acids and ammonia. This fermentation is anaerobic and allows the microbes in the reticulorumen to derive the energy and amino nitrogen in order that they can reproduce. Ruminants absorb the volatile fatty acids across the reticulorumen wall and use them for energy, while the microbes eventually flow out of the rumen into the remainder of the alimentary canal, where they are eventually digested and absorbed. The reticulum, at approximately 5-20 litres, is considerably smaller in capacity than the rumen, which is approximately 100-200 litres in cattle. The oesophageal groove, which links the oesophagus and the omasum is located in the reticulum[WP]." [Wikipedia:Reticulorumen] synonym: "retriculo-rumen" EXACT [] is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0007366 ! ruminant stomach [Term] id: UBERON:0002118 name: right ovary def: "An ovary that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies xref: FMA:7213 ! Right ovary xref: MA:0001705 ! right ovary xref: ncithesaurus:Right_Ovary ! Right Ovary intersection_of: UBERON:0000992 ! female gonad intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:280123002 ! Entire right ovary xref: UMLS:C0227873 [Term] id: UBERON:0002119 name: left ovary def: "An ovary that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] comment: Taxon notes: In some elasmobranchs, the left ovary does not mature, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo[Wikipedia:Ovary#In_other_animals] xref: FMA:7214 ! Left ovary xref: MA:0001704 ! left ovary xref: ncithesaurus:Left_Ovary ! Left Ovary intersection_of: UBERON:0000992 ! female gonad intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:280124008 ! Entire left ovary xref: UMLS:C0227874 [Term] id: UBERON:0010041 name: median ovary is_a: UBERON:0000992 ! female gonad comment: Taxon notes: In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo[Wikipedia:Ovary#In_other_animals] [Term] id: UBERON:0001285 name: nephron def: "The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]" [PMID:9268568, Wikipedia:Nephron] comment: Editor note: kidney terms require review for cross-vertebrate compatibility and developmental relationships. Taxon notes: In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)[GO Kidney] subset: uberon_slim subset: vertebrate_core synonym: "mature nephron" NARROW [EMAPA:28491] xref: BTO:0000924 xref: FMA:17640 ! Nephron xref: GAID:428 ! nephron xref: MA:0000375 ! nephron xref: ncithesaurus:Nephron ! Nephron xref: ZFA:0005282 ! nephron xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/27/Gray1128.png/200px-Gray1128.png xref: MESH:A05.810.453.736 ! nephron xref: EV:0100384 ! nephron xref: EMAPA:28491 ! mature nephron xref: SCTID:361337001 ! Entire nephron is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0007684 {source="FMA"} ! uriniferous tubule relationship: develops_from UBERON:0004208 {evidence="definitional"} ! nephrogenic mesenchyme xref: TAO:0002153 ! nephron synonym: "nephroneum" RELATED LATIN [Wikipedia:Nephron] synonym: "tubulus renalis" RELATED LATIN [Wikipedia:Nephron] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray1128.png property_value: external_definition "Functional unit of the kidney that filters waste.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002153", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0027713 [Term] id: UBERON:0005110 name: metanephric nephron alt_id: UBERON:0005142 def: "A metanephric nephron is the functional unit of the metanephros[GO]." [GO:0072273] xref: VHOG:0000719 ! metanephric nephron intersection_of: UBERON:0001285 ! nephron intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0003220 {source="Wikipedia:Nephron"} ! metanephric blastema relationship: develops_from UBERON:0003220 {source="Wikipedia"} ! metanephric mesenchyme property_value: homology_notes "The primitive form of the vertebrate nephron consists of a vascular filtration surface overlain with podocytes, a specialized coelomic cavity to receive the ultrafiltrate, and a tubule for modification to final urine. Although previously thought to be unique to the vertebrates, this design is now known to be widespread among invertebrates, including most of the protochordates, and especially their larvae.[well established][VHOG]" xsd:string {external_class="VHOG:0000719", ontology="VHOG", source="DOI:10.1093/icb/34.4.542 Ruppert EE\, Evolutionary Origin of the Vertebrate Nephron. Integrative and Comparative Biology (1994)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005722 name: obsolete nephrotome def: "The nephrotome is a section of the mesoderm. It gives rise to the pronephros and eventually to the rest of the kidney. A nephrotome is an obsolete term used to describe rounded mesodermal portions of the forming pronephros. In old texts the pronephros is described as forming through the fusion of multiple nephrotomes. Modern visualization methods such as scanning electron microscopy, in situ hybridization and confocal microscopy, combined with the simple approach of peeling off the epidermis to see the forming kidney, have shown that this is not the case. Nephric mesenchyme separates from the intermediate mesoderm as a single elongated primordia. As this primordia begins to undergo epithelialization the anterior portions of the pronephros form rounded protrusions, which then later become the dorsal branches of the pronephros that link to nephrostomes (distinct from nephrotomes). These rounded bumps are probably the structures observed in histological sections that are referred to as nephrotomes. Nephrostomes are thin ciliated funnels that link pronephric nephrons to the ceolom, and are not related to nephrotomes." [Wikipedia:Nephrotome] synonym: "nephromere" RELATED [Wikipedia:Nephrotome] synonym: "intermediate cell mass" RELATED [BTO:0003673] xref: BTO:0003673 ! nephrotome is_obsolete: true [Term] id: UBERON:0009871 name: nephrogenic zone def: "outer portion of the renal cortex. Site of formation of medullary and cortical elements." [] comment: Taxon notes: see PMID:12761251 for description of nephrogenic zone in dogfish. is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0001225 ! cortex of kidney synonym: "nephrogenic tissue" RELATED [] xref: EMAPA:27721 ! nephrogenic zone xref: MA:0002996 ! nephrogenic zone xref: http://www.gudmap.org/Images/Organ_Summaries/Metanephros/NZ.png [Term] id: UBERON:0005095 ! kidney rudiment name: kidney rudiment comment: Editor notes: class added for consistency with GO - consider merging with kidney mesenchyme. def: "." [GO:0072003] synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0007687 {source="GO"} ! kidney field [Term] id: UBERON:0007687 ! kidney field name: kidney field def: "region of the embryo into the area in which the kidney rudiment will develop." [GO:0072004, GOC:mtg_kidney_jan10] synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0003918 ! kidney mesenchyme name: kidney mesenchyme def: "Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]." [GO:0072074] comment: check this synonym: "mesenchyme of kidney" EXACT [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_into UBERON:0002113 ! kidney [Term] id: UBERON:0004208 ! nephrogenic mesenchyme name: nephrogenic mesenchyme def: "Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron" [GO:0072076] comment: The detailed events associated with the differentiation of the nephrogenic mesenchyme are somewhat complex. It has been suggested that each terminal branch of the ureteric bud stimulates the associated cap mesenchyme tissue to form a renal vesicle (the most primitive stage of nephron development: a stage I nephron). This then elongates, becomes a comma-shaped and then an S-shaped body (stage II nephron), and makes contact with and fuses with the distal component of the ureteric bud. The latter then forms the collecting duct. One fold of the S-shaped body gives rise to Bowman’s capsule (also termed the glomerular capsule). Soon afterwards, endothelial cells invade to make a capillary knot-like outgrowth, the glomerular tuft, which goes on to form the glomerulus. The inner epithelial layer of the Bowman’s capsule (also called the visceral epithelium, or podocyte layer because it consists of podocytes) is closely apposed to the endothelial glomerulus. Together, the Bowman’s capsule and the glomerulus comprise the definitive renal corpuscle. The rest of the nephron elongates to form components of the proximal tubule, the loop of Henle and the distal tubule. The distal pole of the developing nephron connects to the ureteric bud that induced it at an early stage of nephron/ collecting duct development, before differentiation of the proximal tubule, the loop of Henle and the distal tubule are complete. This connection allows the excretory products produced by the kidney to be removed and subsequently transferred, via the ureter, into the bladder where they are stored until it is appropriate to empty the bladder. [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "mesenchyme of nephron" EXACT [OBOL:automatic] synonym: "nephron mesenchyme" EXACT [OBOL:automatic] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_into UBERON:0001285 ! nephron [Term] id: UBERON:0003220 name: metanephric mesenchyme def: "one of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]" [GO:0072075, Wikipedia:Metanephric_blastema] comment: Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] synonym: "metanephric blastema" EXACT [Wikipedia:Metanephric_blastema] synonym: "metanephric mesoderm" EXACT [Wikipedia:Metanephric_blastema] synonym: "metanephrogenic mesenchyme" EXACT [EHDAA:5021] synonym: "metanephros associated mesenchyme" EXACT [RETIRED_EHDAA2:0001139] xref: VHOG:0000540 ! metanephric mesenchyme xref: EHDAA:4041 ! metanephric mesenchyme xref: EHDAA:5915 ! metanephric mesenchyme xref: EMAPA:17208 ! metanephric mesenchyme of metanephros of genitourinary system xref: EMAPA:17375 ! metanephric mesenchyme of metanephros of urinary system xref: EMAPA:29990 ! metanephric mesenchyme of genitourinary system xref: EHDAA:5021 ! metanephrogenic mesenchyme xref: EHDAA2:0004062 ! metanephric mesenchyme xref: SCTID:361529008 ! Metanephric blastema is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_into UBERON:0000081 ! metanephros relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0003074 ! wolffian duct relationship: induced_by UBERON:0000084 {source="ISBN:9780878932504"} ! ureteric bud property_value: external_definition "A mass of intermediate mesodermal cells around the distal end of the ureteric bud that gives rise to nephrons in the metanephric kidney. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000540", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/metanephric+mesenchyme", source="http://bgee.unil.ch/"} property_value: homology_notes "When the ureteric buds emerge from the nephric duct, they enter the metanephrogenic mesenchyme. The ureteric buds induce this mesenchymal tissue to condense around them and differentiate into the nephrons of the mammalian kidney. As this mesenchyme differentiates, it tells the ureteric bud to branch and grow.[well established][VHOG]" xsd:string {external_class="VHOG:0000540", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.462", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0010531 name: metanephros induced blastemal cells def: "." [http://www.embryology.ch/anglais/turinary/urinhaute03.html] comment: AO notes: different versions of EMAPA have different labels for the same classes. In vHOG this is part of metanephros cortex but this leads to a cycle in basic. synonym: "nephrogenic interstitium" RELATED [] synonym: "nephrogenic interstitium of nephrogenic zone" EXACT [EMAPA:17953] synonym: "peripheral blastema" RELATED [EMAPA:17953] synonym: "induced blastemal cells" EXACT [VHOG:0001241] synonym: "cap mesenchyme of metanephros of urinary system" RELATED [EMAPA:17645] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0009871 ! nephrogenic zone relationship: develops_from UBERON:0003220 {source="EHDAA2"} ! metanephric mesenchyme relationship: induced_by UBERON:0000084 ! ureteric bud relationship: has_part CL:0000354 ! blastemal cell xref: VHOG:0001241 ! induced blastemal cells xref: EHDAA:7007 ! induced blastemal cells xref: EHDAA:8105 ! induced blastemal cells xref: EHDAA2:0001143 ! metanephros induced blastemal cells xref: EMAPA:17645 ! cap mesenchyme of metanephros of urinary system (was: induced blastemal cells) xref: EMAPA:17953 ! nephrogenic interstitium of nephrogenic zone (was: induced blastemal cells) [Term] id: UBERON:0005721 ! pronephric mesoderm name: pronephric mesoderm comment: the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney synonym: "pronephric anlage" RELATED [XAO:0000264] synonym: "pronephric bulge" RELATED [XAO:0000264] synonym: "pronephric primordium" RELATED [XAO:0000264] synonym: "pronephric mesenchyme" RELATED [XAO:0000264] xref: TAO:0000067 ! pronephric mesoderm xref: VHOG:0001239 ! pronephric mesoderm xref: XAO:0000264 ! pronephric mesenchyme xref: ZFA:0000067 ! pronephric mesoderm xref: EFO:0003479 ! pronephric mesoderm intersection_of: UBERON:0000926 ! mesoderm intersection_of: develops_into UBERON:0002120 ! pronephros relationship: part_of UBERON:0003064 {source="ZFA"} ! intermediate mesoderm xref: AAO:0011090 ! pronephric mesenchyme relationship: develops_from UBERON:0007297 {evidence="definitional"} ! presumptive pronephric mesoderm property_value: external_definition "Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011090", date_retrieved="2012-06-20", source="XAO:curator"} def: "A mesoderm that develops_into a pronephros." [OBOL:automatic] [Term] id: UBERON:0002120 ! pronephros name: pronephros alt_id: UBERON:0005794 def: "In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]." [GO:0048793, Wikipedia:Pronephros] comment: Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 ! water homeostasis subset: uberon_slim subset: organ_slim synonym: "archinephron" RELATED [BTO:0001541] synonym: "embryonic kidney" RELATED [BTO:0001541] synonym: "pronephron" RELATED [BTO:0001541] xref: EFO:0000927 ! pronephros xref: EHDAA:1017 ! pronephros xref: FMA:72170 ! Pronephros xref: VHOG:0000037 ! pronephros xref: MAT:0000117 ! pronephros xref: MIAA:0000117 ! pronephros xref: ncithesaurus:Pronephros ! Pronephros xref: BTO:0001541 ! pronephros xref: EHDAA2:0001570 ! pronephros xref: EMAPA:16579 ! pronephros xref: TAO:0000151 ! pronephros xref: XAO:0002000 ! pronephric kidney synonym: "pronephric kidney" EXACT [XAO:0002000] xref: ZFA:0000151 ! pronephros xref: AAO:0011089 ! pronephric kidney is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0002113 {source="GO"} ! kidney relationship: located_in UBERON:0003887 {source="OG"} ! intraembryonic coelom relationship: develops_from UBERON:0005721 {source="ZFA"} ! pronephric mesoderm relationship: develops_from UBERON:0005754 ! rostral part of nephrogenic cord relationship: develops_from UBERON:0005095 {source="GO"} ! kidney rudiment xref: SCTID:308804007 ! Entire pronephros property_value: external_definition "Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011089", date_retrieved="2012-06-20", source="XAO:curator"} property_value: external_definition "The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000151", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000037", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {external_class="VHOG:0000037", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.637", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "pronephric" xsd:string xref: UMLS:C0231048 [Term] id: UBERON:0002122 ! capsule of thymus name: capsule of thymus def: "the fibrous connective tissue surrounding the thymus." [MP:0002368] comment: This class was created automatically from a combination of ontologies synonym: "thymus capsule" EXACT [] synonym: "thymic capsule" EXACT [] xref: FMA:72204 ! Capsule of thymus xref: MA:0000766 ! thymus capsule xref: ncithesaurus:Thymic_Capsule ! Thymic Capsule is_a: UBERON:0003893 ! capsule intersection_of: UBERON:0003893 ! capsule intersection_of: surrounds UBERON:0002370 ! thymus relationship: surrounds UBERON:0002370 ! thymus xref: SCTID:188181003 ! Entire thymic capsule xref: UMLS:C0229945 [Term] id: UBERON:0002123 name: cortex of thymus def: "Cortical portion of thymus, mainly composed of lymphoid cells, supported by a network of finely-branched epithelial reticular cells, which is continuous with a similar network in the medullary portion. This network forms an adventitia to the blood vessels. The cortex is the location of the earliest events in thymocyte development, where T cell receptor gene rearrangement and positive selection takes place." [Wikipedia:Thymus#Cortex] comment: Histologically, the thymus can be divided into a central medulla and a peripheral cortex which is surrounded by an outer capsule. The cortex and medulla play different roles in the development of T cells. Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin[WP] synonym: "thymus cortex" EXACT [MA:0000767] synonym: "thymic cortex" EXACT [BTO:0002934] xref: BTO:0002934 ! thymic cortex xref: FMA:72205 ! Cortex of thymus xref: MA:0000767 ! thymus cortex xref: ncithesaurus:Thymus_Cortex ! Thymus Cortex intersection_of: UBERON:0001851 ! cortex intersection_of: part_of UBERON:0002370 ! thymus relationship: has_function_in GO:0045058 ! T cell selection xref: SCTID:188262003 ! Entire thymic cortex relationship: present_in_taxon NCBITaxon:7955 {source="doi:10.1177/0192623311409597"} ! Danio rerio xref: UMLS:C0229948 [Term] id: UBERON:0002124 name: medulla of thymus def: "Medullary portion of thymus. The reticulum is coarser than in the cortex, the lymphoid cells are relatively fewer in number, and there are found peculiar nest-like bodies, the concentric corpuscles of Hassall. These concentric corpuscles are composed of a central mass, consisting of one or more granular cells, and of a capsule formed of epithelioid cells. They are the remains of the epithelial tubes, which grow out from the third branchial pouches of the embryo to form the thymus. Each follicle is surrounded by a vascular plexus, from which vessels pass into the interior, and radiate from the periphery toward the center, forming a second zone just within the margin of the medullary portion. In the center of the medullary portion there are very few vessels, and they are of minute size." [Wikipedia:Thymus#Medulla] comment: This class was created automatically from a combination of ontologies synonym: "thymus medulla" EXACT [] synonym: "medulla of thymus gland" EXACT [OBOL:automatic] synonym: "thymus gland medulla" EXACT [OBOL:automatic] xref: FMA:72206 ! Medulla of thymus xref: MA:0000771 ! thymus medulla xref: ncithesaurus:Thymus_Medulla ! Thymus Medulla xref: EFO:0001969 ! medulla of thymus xref: BTO:0004560 ! thymic medulla is_a: UBERON:0000958 ! medulla intersection_of: UBERON:0000958 ! medulla intersection_of: part_of UBERON:0002370 ! thymus relationship: part_of UBERON:0002370 ! thymus xref: SCTID:188344009 ! Entire thymic medulla relationship: present_in_taxon NCBITaxon:7955 {source="doi:10.1177/0192623311409597"} ! Danio rerio xref: UMLS:C0229949 [Term] id: UBERON:0002125 name: lobule of thymus def: "the basic structural unit of the thymus." [MP:0002367] comment: This class was created automatically from a combination of ontologies synonym: "thymus lobule" EXACT [MA:0000770] synonym: "thymic lobule" EXACT [] xref: FMA:72215 ! Lobule of thymus xref: MA:0000770 ! thymus lobule xref: ncithesaurus:Thymic_Lobule ! Thymic Lobule is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002370 ! thymus xref: SCTID:187882006 ! Entire thymic lobule xref: UMLS:C1522462 [Term] id: UBERON:0006936 name: thymus subcapsular epithelium comment: todo - check whether this is part of the thymus or borders it xref: MA:0000769 ! thymus subcapsular epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002122 ! capsule of thymus relationship: has_part CL:0002294 ! type-1 epithelial cell of thymus def: "An epithelium that is part of a capsule of thymus." [OBOL:automatic] [Term] id: UBERON:0002718 name: solitary tract def: "The solitary tract is a compact fiber bundle that extends longitudinally through the posterolateral region of the medulla. The solitary tract is surrounded by the nucleus of the solitary tract, and descends to the upper cervical segments of the spinal cord. [WP,unvetted]." [Wikipedia:Solitary_tract] subset: uberon_slim synonym: "respiratory bundle of Gierke" EXACT [] xref: FMA:72619 ! Solitary tract xref: NIF_GrossAnatomy:birnlex_1483 ! Solitary tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/93/Gray695.png/200px-Gray695.png xref: BM:Me-ST ! solitary tract is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata synonym: "tractus solitarius medullae oblongatae" RELATED LATIN [Wikipedia:Solitary_tract] xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Gray695.png [Term] id: UBERON:0002126 ! solitary tract nuclear complex name: solitary tract nuclear complex def: "The solitary tract and nucleus are structures in the brainstem that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX) and vagus (X) cranial nerves. [WP,unvetted]." [Wikipedia:Nucleus_of_tractus_solitarius] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "nuclei of solitary tract" EXACT [] synonym: "solitary nuclei" EXACT [] xref: FMA:72242 ! Solitary tract nuclear complex xref: SCTID:369080003 ! Entire nucleus of tractus solitarius is_a: UBERON:0007245 ! nuclear complex of neuraxis relationship: part_of UBERON:0001896 {source="MA-abduced"} ! medulla oblongata relationship: spatially_disjoint_from UBERON:0002162 {source="ABA"} ! area postrema relationship: spatially_disjoint_from UBERON:0002610 {source="ABA"} ! cochlear nuclear complex relationship: spatially_disjoint_from UBERON:0002864 {source="ABA"} ! accessory cuneate nucleus relationship: spatially_disjoint_from UBERON:0007633 {source="ABA"} ! nucleus of trapezoid body relationship: spatially_disjoint_from UBERON:0002866 {source="ABA"} ! caudal part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002873 {source="ABA"} ! interpolar part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002591 {source="ABA"} ! oral part of spinal trigeminal nucleus relationship: has_function_in GO:0003019 ! central nervous system control of baroreceptor feedback synonym: "nucleus tractus solitarii" EXACT LATIN [FMA:TA, FMA:72242] [Term] id: UBERON:0009050 name: nucleus of solitary tract def: "A neural nucleus that is part of the solitary tract nuclear complex. The solitary tract and nucleus are structures in the brainstem that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX) and vagus (X) cranial nerves. [WP,unvetted]." [OBOL:automatic, Wikipedia:Solitary_nucleus] synonym: "solitary nucleus" EXACT [] synonym: "nucleus of tractus solitarius" EXACT [Wikipedia:Solitary_nucleus] synonym: "nucleus of the tractus solitarius" EXACT [NIF_GrossAnatomy:birnlex_1429] synonym: "solitary tract nucleus" EXACT [] is_a: UBERON:0011775 {source="Wikipedia"} ! vagus nerve nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002126 ! solitary tract nuclear complex xref: NIF_GrossAnatomy:birnlex_1429 ! Solitary nucleus xref: ncithesaurus:Solitary_Nucleus ! Solitary Nucleus xref: ncithesaurus:Nucleus_of_the_Solitary_Tract ! Nucleus of the Solitary Tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png xref: BTO:0003963 ! nucleus solitarius xref: MA:0001052 ! solitary tract nucleus xref: FMA:256691 ! nucleus of solitary tract xref: EV:0100288 ! nucleus of the tractus solitarius xref: BM:Me-NS ! nucleus of solitary tract xref: GAID:593 ! solitary nucleu xref: MESH:A08.186.211.132.810.406.750 ! solitary nucleu xref: ABA:NTS ! Nucleus of the solitary tract synonym: "nucleus tractus solitarii medullae oblongatae" RELATED LATIN [Wikipedia:Solitary_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png xref: UMLS:C0175518 [Term] id: UBERON:0009051 name: gelatinous nucleus of solitary tract is_a: UBERON:0009050 {source="FMA"} ! nucleus of solitary tract xref: FMA:77463 ! gelatinous nucleus of solitary tract xref: ABA:NTSge ! Nucleus of the solitary tract, gelatinous part [Term] id: UBERON:0009052 name: medial nucleus of solitary tract is_a: UBERON:0009050 {source="FMA"} ! nucleus of solitary tract xref: FMA:229585 ! medial nucleus of solitary tract xref: ABA:NTSm ! Nucleus of the solitary tract, medial part [Term] id: UBERON:0007245 ! nuclear complex of neuraxis name: nuclear complex of neuraxis def: "Internal gray matter component which consists of an assemblage of nuclei of neuraxis. Example: cerebellar nuclear complex, Vestibular nuclear complex.[FMA]" [FMA:84059, FMA:FMA] comment: todo - move existing complex classes currently under nucleus to be under this class synonym: "nuclear complex" RELATED [] synonym: "neural nuclei" RELATED [] synonym: "cluster of neural nuclei" RELATED [] xref: FMA:84059 ! nuclear complex of neuraxis is_a: UBERON:0002020 ! gray matter of neuraxis relationship: composed_primarily_of UBERON:0000125 ! neural nucleus [Term] id: UBERON:0000128 name: olivary body def: "prominent oval structure in the medulla oblongata, present in pairs, the lower portion of the brainstem. They contain the olivary nuclei" [Wikipedia:Olivary_body] synonym: "olive" RELATED [] synonym: "olive body" EXACT [] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Gray679.png/200px-Gray679.png xref: BTO:0002299 ! oliva is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:279293003 ! Entire olivary body synonym: "oliva" RELATED LATIN [Wikipedia:Olivary_body] xref: http://upload.wikimedia.org/wikipedia/commons/9/9a/Gray679.png [Term] id: UBERON:0002127 name: inferior olivary complex def: "largest nucleus situated in the olivary body, part of the medulla oblongata. It is closely associated with the cerebellum, but its specific function is voluntary body movements." [Wikipedia:Inferior_olivary_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "inferior olivary nuclear complex" EXACT [FMA:72243] synonym: "inferior olivary nucleus" RELATED [FMA:72243] synonym: "inferior olive" EXACT [FMA:72243] synonym: "caudal olivary nuclei" RELATED [BTO:0002298] synonym: "complexus olivaris inferior" RELATED [BTO:0002298] synonym: "inferior olivary nuclei" RELATED [BTO:0002298] synonym: "nuclei olivares caudales" RELATED [BTO:0002298] synonym: "nuclei olivares inferiores" RELATED [BTO:0002298] xref: FMA:72243 ! Inferior olivary complex xref: MA:0001040 ! inferior olive xref: NIF_GrossAnatomy:birnlex_1164 ! Inferior olivary complex xref: TAO:0000215 ! inferior olive xref: ZFA:0000215 ! inferior olive xref: BTO:0002298 ! inferior olivary complex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/72/CerebCircuit.png/200px-CerebCircuit.png xref: EV:0100277 ! inferior olivary nuclei xref: ABA:IO ! Inferior olivary complex xref: BM:Me-IO ! inferior olivary complex is_a: UBERON:0007245 ! nuclear complex of neuraxis relationship: part_of UBERON:0000128 ! olivary body relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus synonym: "oliva" EXACT LATIN [FMA:TA, FMA:72243] synonym: "complexus olivaris inferior; nuclei olivares inferiores" RELATED LATIN [Wikipedia:Inferior_olivary_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/7/72/CerebCircuit.png xref: VHOG:0001627 ! inferior olive property_value: homology_notes "The inferior olive appears to be present in all vertebrate classes and is particularly well developed in species with a well-developed cerebellum.[well established][VHOG]" xsd:string {external_class="VHOG:0001627", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.256", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0007244 ! inferior olivary nucleus name: inferior olivary nucleus def: "The inferior olivary nucleus is the largest nucleus situated in the olivary body, part of the medulla oblongata." [Wikipedia:Inferior_olivary_nucleus] synonym: "inferior olive" RELATED [Wikipedia:Inferior_olivary_nucleus] xref: BTO:0003844 ! inferior olivary nucleus xref: EMAPA:19241 ! inferior olivary nucleus xref: VHOG:0001380 ! inferior olivary nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002127 ! inferior olivary complex xref: SCTID:369066005 ! Entire inferior olivary nucleus [Term] id: UBERON:0013608 name: inferior olive dorsal accessory nucleus synonym: "dorsal accessory nucleus of inferior olivary complex" EXACT [] is_a: UBERON:0007244 {source="MA-inferred"} ! inferior olivary nucleus xref: MA:0001042 ! inferior olive dorsal accessory nucleus [Term] id: UBERON:0013609 name: inferior olive medial accessory nucleus synonym: "medial accessory nucleus of inferior olivary complex" EXACT [] is_a: UBERON:0007244 {source="MA-inferred"} ! inferior olivary nucleus xref: MA:0001044 ! inferior olive medial accessory nucleus [Term] id: UBERON:0013610 name: inferior olive ventral accessory nucleus synonym: "ventral accessory nucleus of inferior olivary complex" EXACT [] is_a: UBERON:0007244 {source="cjm"} ! inferior olivary nucleus [Term] id: UBERON:0002128 ! superior olivary complex name: superior olivary complex def: "The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound[GO]." [Wikipedia:Superior_olivary_complex] comment: GO -- In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. -- TODO fix GO def to be the same throughout subset: uberon_slim synonym: "superior olivary nuclei" EXACT [FMA:72247] synonym: "superior olivary nucleus" RELATED [FMA:72247] synonym: "superior olive" EXACT [FMA:72247] xref: FMA:72247 ! Superior olivary complex xref: NIF_GrossAnatomy:birnlex_1307 ! Superior olivary complex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/46/Gray713.png/200px-Gray713.png xref: EV:0100263 ! superior olivary nucleus xref: ABA:SOC ! Superior olivary complex is_a: UBERON:0007245 ! nuclear complex of neuraxis relationship: part_of UBERON:0000988 ! pons relationship: spatially_disjoint_from UBERON:0006840 {source="ABA"} ! nucleus of lateral lemniscus relationship: spatially_disjoint_from UBERON:0007634 {source="ABA"} ! parabrachial nucleus relationship: spatially_disjoint_from UBERON:0002597 {source="ABA"} ! principal sensory nucleus of trigeminal nerve synonym: "nucleus olivaris superior" EXACT LATIN [FMA:TA, FMA:72247] synonym: "nucleus olivaris superior" RELATED LATIN [Wikipedia:Superior_olivary_complex] xref: http://upload.wikimedia.org/wikipedia/commons/4/46/Gray713.png [Term] id: UBERON:0007247 ! superior olivary nucleus name: superior olivary nucleus synonym: "superior olive" RELATED [MA:0001026] synonym: "nucleus of superior olivary complex" EXACT [FMA:72246] xref: FMA:72246 ! nucleus of superior olivary complex xref: MA:0001026 ! superior olivary nucleus xref: VHOG:0001381 ! superior olivary nucleus is_a: UBERON:0006331 ! brainstem nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002128 ! superior olivary complex xref: SCTID:369024009 ! Entire superior olivary nucleus synonym: "superior olivary complex nucleus" EXACT [FMA:72246] def: "A nucleus of brain that is part of a superior olivary complex." [OBOL:automatic] [Term] id: UBERON:0002158 name: principal inferior olivary nucleus def: "The inferior olivary nucleus that consists of the major laminar structure." [Wikipedia:Olivary_body#Olivary_nuclei] comment: This class was created automatically from a combination of ontologies synonym: "chief inferior olivary nucleus" EXACT [] synonym: "inferior olivary complex, principal olive" EXACT [] synonym: "inferior olive principal nucleus" EXACT [] synonym: "inferior olive, principal nucleus" EXACT [] synonym: "main olivary nucleus" EXACT [] synonym: "principal nucleus of inferior olive" EXACT [] synonym: "principal olivary nucleus" EXACT [] synonym: "convoluted olive" EXACT [NIF_GrossAnatomy:nlx_anat_20081248] synonym: "principal olive" EXACT [NIF_GrossAnatomy:nlx_anat_20081248] xref: FMA:72592 ! Principal inferior olivary nucleus xref: MA:0001046 ! inferior olive principal nucleus xref: NIF_GrossAnatomy:nlx_anat_20081248 ! Principal olivary nucleus is_a: UBERON:0007244 ! inferior olivary nucleus synonym: "nucleus olivaris principalis" EXACT LATIN [FMA:TA, FMA:72592] [Term] id: UBERON:0002159 name: medial accessory inferior olivary nucleus def: "The inferior olivary nucleus that lies between the primary olivary nucleus and the pyramid, and forms a curved lamina, the concavity of which is directed laterally" [Wikipedia:Olivary_body#Olivary_nuclei] comment: This class was created automatically from a combination of ontologies synonym: "inferior olivary complex, medial accessory olive" EXACT [] synonym: "inferior olive medial nucleus" EXACT [] synonym: "inferior olive, medial nucleus" EXACT [] synonym: "medial accessory olivary nucleus" EXACT [] xref: FMA:72594 ! Medial accessory inferior olivary nucleus xref: MA:0001045 ! inferior olive medial nucleus is_a: UBERON:0007244 ! inferior olivary nucleus synonym: "nucleus olivaris accessorius medialis" EXACT LATIN [FMA:TA, FMA:72594] xref: SCTID:369069003 ! Entire medial accessory olivary nucleus [Term] id: UBERON:0007249 name: dorsal accessory inferior olivary nucleus def: "The inferior olivary nucleus that is the smallest, and appears on transverse section as a curved lamina behind the primary olivary nucleus" [Wikipedia:Olivary_body#Olivary_nuclei] synonym: "dorsal accessory olivary nucleus" EXACT [FMA:72593] synonym: "inferior olivary complex, dorsal accessory olive" EXACT [FMA:72593] synonym: "inferior olive, dorsal nucleus" EXACT [FMA:72593] synonym: "posterior accessory olivary nucleus" EXACT [FMA:72593] xref: FMA:72593 ! dorsal accessory inferior olivary nucleus is_a: UBERON:0007244 ! inferior olivary nucleus synonym: "nucleus olivaris accessorius posterior" EXACT LATIN [FMA:TA, FMA:72593] xref: SCTID:369068006 ! Entire dorsal accessory olivary nucleus [Term] id: UBERON:0002782 name: medial superior olivary nucleus def: "The superior olivary complex (or SOC or superior olive) is a small mass of gray substance situated on the dorsal surface of the lateral part of the trapezoid body. Small in humans, but well developed in certain animals, it exhibits similar structure as the inferior olivary nucleus, and is situated immediately above it. Some of the fibers of the trapezoid body end by arborizing around the cells of this nucleus, while others arise from these cells. [WP,unvetted]." [Wikipedia:Superior_olivary_complex] subset: uberon_slim synonym: "chief nucleus of superior olive" EXACT [FMA:72473] synonym: "chief superior olivary nucleus" EXACT [FMA:72473] synonym: "main superior olivary nucleus" EXACT [FMA:72473] synonym: "medial superior olive" EXACT [FMA:72473] synonym: "principal superior olivary nucleus" EXACT [FMA:72473] synonym: "superior olivary nucleus, medial part" EXACT [FMA:72473] synonym: "nucleus laminaris" EXACT [NIF_GrossAnatomy:birnlex_1682] xref: FMA:72473 ! Medial superior olivary nucleus xref: NIF_GrossAnatomy:birnlex_1682 ! Medial superior olivary nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/46/Gray713.png/200px-Gray713.png xref: BM:Pons-SOM ! medial superior olivary nucleus is_a: UBERON:0007247 ! superior olivary nucleus [Term] id: UBERON:0002779 name: lateral superior olivary nucleus def: "In anatomy, the olivary bodies or simply olives (Latin oliva and olivae, singular and plural, respectively) are a pair of prominent oval structures in the medulla oblongata, the lower portion of the brainstem. They contain the olivary nuclei. [WP,unvetted]." [Wikipedia:Olivary_body] subset: uberon_slim synonym: "accessory olivary nucleus" EXACT [FMA:72472] synonym: "accessory superior olivary nucleus" EXACT [FMA:72472] synonym: "accessory superior olive" EXACT [FMA:72472] synonym: "lateral superior olive" EXACT [FMA:72472] synonym: "superior olivary nucleus, lateral part" EXACT [FMA:72472] xref: FMA:72472 ! Lateral superior olivary nucleus xref: NIF_GrossAnatomy:birnlex_1675 ! Lateral superior olivary nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Gray679.png/200px-Gray679.png xref: BM:Pons-SOL ! lateral superior olivary nucleus is_a: UBERON:0007247 ! superior olivary nucleus xref: SCTID:360477003 ! Accessory olivary nucleus [Term] id: UBERON:0002129 name: cerebellar cortex def: "The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function[GO]." [Wikipedia:Cerebellar_cortex] comment: The circuits in the cerebellar cortex look similar across all classes of vertebrates, including fish, reptiles, birds, and mammals (e.g., Fig. 2). This has been taken as evidence that the cerebellum performs functions important to all vertebrate species. (Wikipedia) subset: uberon_slim synonym: "cortex cerebellaris" RELATED [BTO:0000043] xref: BTO:0000043 xref: FMA:72248 ! Cerebellar cortex xref: GAID:596 ! cerebellar cortex xref: MA:0000199 ! cerebellar cortex xref: NIF_GrossAnatomy:birnlex_1566 ! Cerebellar cortex xref: ncithesaurus:Cerebellar_Cortex ! Cerebellar Cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Cerebellum_NIH.png/200px-Cerebellum_NIH.png xref: MESH:A08.186.211.132.810.428.200.212 ! cerebellar cortex xref: EV:0100294 ! cerebellum cortex xref: ABA:CBX ! Cerebellar cortex xref: BM:CB-Cbx ! cerebellar cortex is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002037 ! cerebellum relationship: has_function_in GO:0007613 {source="Wikipedia"} ! memory relationship: spatially_disjoint_from UBERON:0002130 {source="ABA"} ! cerebellar nuclear complex xref: SCTID:361593004 ! Entire cerebellar cortex xref: VHOG:0001597 ! cerebellar cortex xref: UMLS:C0007759 [Term] id: UBERON:0002138 name: habenulo-interpeduncular tract comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "fasciculus retroflexus" EXACT [] synonym: "habenulointerpeduncular fasciculus" EXACT [] synonym: "habenulointerpeduncular tract" RELATED [] synonym: "habenulopeduncular tract" EXACT [] synonym: "Meynert's retroflex bundle" EXACT [] synonym: "tractus habenulo-interpeduncularis" EXACT [ZFA:0000353] synonym: "fasciculus retroflexus (meynert)" EXACT [NIF_GrossAnatomy:birnlex_1504] xref: FMA:72400 ! Habenulo-interpeduncular tract xref: NIF_GrossAnatomy:birnlex_1504 ! Fasciculus retroflexus xref: TAO:0000353 ! fasciculus retroflexus xref: ZFA:0000353 ! fasciculus retroflexus xref: BM:HPT ! habenulopeduncular tract is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001894 ! diencephalon xref: SCTID:369194000 ! Entire habenulopeduncular tract [Term] id: UBERON:0011357 ! Reissner's fiber name: Reissner's fiber def: "An acellular strand that runs from subcommissural organ caudally through the ventricular system and central canal to the ampulla caudalis. Develops from glycoproteins secreted into CSF." [ISBN10:0471888893, Wikipedia:Reissner's_fiber] comment: Taxon notes: Reissner's fiber is present in the central canal of species in all chordate subphyla[Olsson R. (1993) Reissner's fiber mechanisms: some common denominators. In The Subcommissural Organ: An Ependymal Brain Gland ] synonym: "Reissner's fibre" EXACT [] is_a: UBERON:0000476 ! acellular anatomical structure relationship: part_of UBERON:0001017 ! central nervous system relationship: present_in_taxon NCBITaxon:7711 {source="ISBN10:0471888893"} ! Chordata relationship: composed_primarily_of PR:000015658 ! SCO-spondin [Term] id: UBERON:0011358 name: infundibular organ def: "." [] comment: Resembles the subcommisural organ structurally, ultrastructurally and immunochemically[Niewenhuys] Gives rise to Reissner's fiber; however secretions are not identical to those of SCO [PMID:9550137][doi:10.1007/BF00303086] synonym: "infundibular organ of Boeke" EXACT [] synonym: "ventral infundibular organ" EXACT [] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001017 ! central nervous system relationship: has_part CL:0000065 ! ependymal cell relationship: secretes UBERON:0011357 ! Reissner's fiber relationship: present_in_taxon NCBITaxon:7737 {source="doi:10.1111/j.1463-6395.1976", stage="larval"} ! Branchiostoma [Term] id: UBERON:0011360 name: ampulla caudalis def: "A ventricle-like space at the end of the central canal" [ISBN10:0471888893] is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002291 {notes="in caudal end of"} ! central canal [Term] id: UBERON:0002139 name: subcommissural organ def: "The subcommissural organ is a circumventricular organ consisting of ependymal cells which secrete SCO-spondin[WP,partially vetted]." [Wikipedia:Subcommissural_organ, PMID:9579598] comment: Occurs throughout the vertebartes [PMID:9579598, doi:10.1002/ar.1091260210]. First appears in hagfish(Olsson). In many species, including the human, it reaches its full development during embryonic life[PMID:9579598]. During the course of phyletic evolution, one notes various changes. Indeed, in lower vertebrates, the SCO presents a greater degree of enzyme activity than the ependyma while in birds the ependyma demonstrates a more intense activity than the SCO[PMID:479574] Sometimes preceded by flexural organ[doi:10.1007/BF00303086] subset: uberon_slim subset: vertebrate_core synonym: "dorsal subcommissural organ" RELATED [] synonym: "SCO" RELATED [] xref: FMA:72414 ! Subcommissural organ xref: GAID:794 ! subcommissural organ xref: NIF_GrossAnatomy:birnlex_1028 ! Subcommissural organ xref: BTO:0001820 ! subcommissural organ xref: MA:0002941 ! subcommissural organ xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d7/Gray715.png/200px-Gray715.png xref: MESH:A08.713.810 ! subcommissural organ is_a: UBERON:0010134 {source="MA"} ! secretory circumventricular organ relationship: part_of UBERON:0002314 {source="MA"} ! midbrain tectum relationship: part_of UBERON:0011357 ! Reissner's fiber relationship: has_part CL:0000065 ! ependymal cell relationship: secretes PR:000015658 ! SCO-spondin relationship: present_in_taxon NCBITaxon:7742 {source="multiple"} ! Vertebrata xref: SCTID:369193006 ! Entire subcommissural organ xref: ZFA:0000683 ! subcommissural organ xref: TAO:0000683 ! subcommissural organ synonym: "organum subcommissurale" RELATED LATIN [Wikipedia:Subcommissural_organ] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png [Term] id: UBERON:0011577 name: flexural organ def: "a portion of tissue that is the most anterior portion of the notochord. The flexural organ secretes Reissner's fiber-related proteins, including F-spondin." [https://sourceforge.net/tracker/?group_id=76834&atid=994726, ZFA:0007071] comment: Taxon notes: may be an ontogenetical remnant of the infundibular organ in cephalochordates. Editor notes: we cannot classify as a secretory circumventricular organ, as this leads to unsatisfiability is_a: UBERON:0000481 ! multi-tissue structure relationship: develops_into UBERON:0010134 {notes="unvetted"} ! secretory circumventricular organ relationship: part_of UBERON:0002328 {source="ZFA"} ! notochord relationship: present_in_taxon NCBITaxon:7711 ! Chordata relationship: secretes PR:000015557 ! spondin-1 xref: ZFA:0007071 [Term] id: UBERON:0002141 name: parvocellular oculomotor nucleus def: "The Edinger-Westphal nucleus (also known as the accessory oculomotor nucleus) is the accessory parasympathetic cranial nerve nucleus of the oculomotor nerve, supplying the constricting muscles of the iris. Alternatively, the Edinger-Westphal nucleus is a term often used to refer to the adjacent population of non-preganglionic neurons that do not project to the ciliary ganglion, but rather project to the spinal cord, dorsal raphe nucleus, and septal nuclei. Unlike the classical, preganglionic Edinger-Westphal neurons that contain choline acetyltransferase, neurons of the non-preganglionic Edinger-Westphal nucleus have been shown to contain various stress- and feeding-related neuropeptides, such as Urocortin and cocaine- and amphetamine-regulated transcript. Proper nomenclature for this distinct brain region has not yet been established. [WP,unvetted]." [Wikipedia:Edinger-westphal_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "accessory oculomotor nucleus" EXACT [] synonym: "edinger-westphal nucleus" EXACT [] synonym: "oculomotor nucleus, parvocellular part" EXACT [] synonym: "nucleus Edinger-Westphal" EXACT [ZFA:0000244] xref: FMA:72424 ! Parvocellular oculomotor nucleus xref: MA:0001071 ! edinger-westphal nucleus xref: NIF_GrossAnatomy:birnlex_822 ! Parvocellular oculomotor nucleus xref: ZFA:0000244 ! nucleus Edinger-Westphal xref: ABA:EW ! Edinger-Westphal nucleus xref: BM:EW ! Edinger-Westphal nucleus is_a: UBERON:0000126 ! cranial nerve nucleus relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus xref: SCTID:62088007 ! Edinger Westphal nucleus xref: TAO:0000244 ! nucleus Edinger-Westphal [Term] id: UBERON:0002142 name: pedunculopontine tegmental nucleus def: "The pedunculopontine nucleus (PPN) (or pedunculopontine tegmental nucleus, PPTN) is located in the brainstem, caudal to the substantia nigra and adjacent to the superior cerebellar peduncle. It is composed by a wide variety of neurochemical cell types, including cholinergic, glutamatergic and GABAergic cells. In the classical sense, the PPN is considered to be one of the main components of the reticular activating system. [WP,unvetted]." [Wikipedia:Pedunculopontine_tegmental_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "peduncular pontine nucleus" EXACT [] synonym: "pedunculopontine nucleus" EXACT [] xref: FMA:72429 ! Pedunculopontine tegmental nucleus xref: MA:0001020 ! peduncular pontine nucleus xref: NIF_GrossAnatomy:birnlex_1437 ! Pedunculopontine tegmental nucleus xref: ABA:PPN ! Pedunculopontine nucleus xref: BM:Pons-PPT ! pedunculopontine tegmental nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0000988 ! pons relationship: part_of UBERON:0002275 ! reticular formation relationship: spatially_disjoint_from UBERON:0007412 {source="ABA"} ! midbrain raphe nuclei relationship: spatially_disjoint_from UBERON:0001965 {source="ABA"} ! substantia nigra pars compacta [Term] id: UBERON:0002143 name: dorsal tegmental nucleus comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "dorsal tegmental nucleus (gudden)" EXACT [] synonym: "gudden nucleus" EXACT [] synonym: "posterior tegmental nucleus" EXACT [] synonym: "von Gudden's nucleus" EXACT [] synonym: "nucleus tegmentalis dorsalis" EXACT [ZFA:0000346] synonym: "dorsal tegmental nucleus of gudden" EXACT [NIF_GrossAnatomy:birnlex_992] xref: FMA:72434 ! Dorsal tegmental nucleus xref: MA:0001013 ! dorsal tegmental nucleus xref: NIF_GrossAnatomy:birnlex_992 ! Dorsal tegmental nucleus xref: TAO:0000346 ! dorsal tegmental nucleus xref: ZFA:0000346 ! dorsal tegmental nucleus xref: VHOG:0001368 ! dorsal tegmental nucleus xref: ABA:DTN ! Dorsal tegmental nucleus xref: BM:TD ! dorsal tegmental nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus synonym: "nucleus tegmentalis posterior" EXACT LATIN [FMA:TA, FMA:72434] [Term] id: UBERON:0002144 name: peripeduncular nucleus def: "a group of neuron cell bodies that form a thin, caplike configuration over the dorsolateral aspect of the crus cerebri; many of its cells are acetylcholinesterase positive." [http://www.medilexicon.com/medicaldictionary.php?t=61630] comment: Note that FMA and NIF support this being part of midbrain tegmentum; MA places this in the thalamus and ABA supports thalamus. todo - check. for now we take a conservative position and assert overlaps for both rather than part of synonym: "peripeduncular nucleus of pons" EXACT [FMA:72437] xref: FMA:72437 ! Peripeduncular nucleus xref: MA:0000875 ! peripeduncular nucleus xref: NIF_GrossAnatomy:birnlex_1474 ! Peripeduncular nucleus xref: ABA:PP ! Peripeduncular nucleus xref: BM:MB-PPN ! peripeduncular nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: overlaps UBERON:0001900 {source="MA"} ! subthalamus relationship: overlaps UBERON:0001943 {source="NIF"} ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002704 {source="ABA"} ! metathalamus relationship: spatially_disjoint_from UBERON:0002776 {source="ABA"} ! ventral nuclear group xref: SCTID:25949000 ! Peripeduncular nucleus [Term] id: UBERON:0002145 name: interpeduncular nucleus comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "interpeduncular ganglion" EXACT [] synonym: "interpedunclear nucleus" RELATED [MTB:379] xref: FMA:72439 ! Interpeduncular nucleus xref: MA:0001069 ! interpeduncular nucleus xref: NIF_GrossAnatomy:birnlex_1000 ! Interpeduncular nucleus xref: ZFA:0000903 ! interpeduncular nucleus tegmentum xref: ABA:IPN ! Interpeduncular nucleus xref: BM:MB-IP ! interpeduncular nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 {source="NIF"} ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002043 {source="ABA"} ! dorsal raphe nucleus xref: TAO:0000903 ! interpeduncular nucleus tegmentum synonym: "interpeduncular nucleus tegmentum" RELATED [TAO:0000903] [Term] id: UBERON:0002146 name: pulmonary valve def: "Cardiac valve which has as its parts the right anterior, left anterior and posterior cusps, attached to the fibrous ring of pulmonary valve.[FMA]" [Wikipedia:Pulmonary_valve, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "pulmonic valve" EXACT [] xref: EHDAA:4412 ! pulmonary valve xref: FMA:7246 ! Pulmonary valve xref: GAID:566 ! pulmonary valve xref: VHOG:0000814 ! pulmonary valve xref: MA:0000089 ! pulmonary valve xref: ncithesaurus:Pulmonary_Valve ! Pulmonary Valve xref: galen:PulmonaryValve ! pulmonary valve xref: OpenCyc:Mx4rwP6uq5wpEbGdrcN5Y29ycA ! pulmonary valve xref: EHDAA2:0001577 ! pulmonary valve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/20/Diagram_of_the_human_heart_%28cropped%29.svg/200px-Diagram_of_the_human_heart_%28cropped%29.svg.png xref: EMAPA:17872 ! pulmonary valve xref: MESH:A07.541.510.738 ! pulmonary valve is_a: UBERON:0005623 {source="MA"} ! semi-lunar valves xref: SCTID:181289004 ! Entire pulmonary valve synonym: "valva trunci pulmonalis" RELATED LATIN [Wikipedia:Pulmonary_valve] xref: http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg property_value: external_definition "The valve with semilunar cusps at the entrance to the pulmonary trunk from the right ventricle of the heart. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000814", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/pulmonary+valve", source="http://bgee.unil.ch/"} xref: UMLS:C0034086 [Term] id: UBERON:0002147 name: reticulotegmental nucleus comment: This class was created automatically from a combination of ontologies synonym: "reticular tegmental nucleus" EXACT [] synonym: "reticulotegmental nucleus of pons" EXACT [] synonym: "tegmental reticular nucleus, pontine gray" EXACT [] xref: FMA:72471 ! Reticulotegmental nucleus xref: MA:0001025 ! reticular tegmental nucleus xref: NIF_GrossAnatomy:birnlex_882 ! Reticulotegmental nucleus xref: ABA:TRN ! Tegmental reticular nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0000988 ! pons relationship: part_of UBERON:0002275 ! reticular formation relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus synonym: "nucleus reticularis tegmenti pontis" EXACT LATIN [FMA:TA, FMA:72471] [Term] id: UBERON:0002148 name: locus ceruleus def: "The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]." [Wikipedia:Locus_ceruleus, GO:0021703, GAID:577] comment: TODO - check ZFA/pons. also GO says part of dorsorostral pons subset: uberon_slim subset: vertebrate_core synonym: "caerulean nucleus" EXACT [] synonym: "locus coeruleus" EXACT [] synonym: "locus coeruleu" EXACT [] synonym: "nucleus of locus caeruleus" EXACT [] synonym: "locus caeruleus" EXACT [NIF_GrossAnatomy:birnlex_905] synonym: "nucleus pigmentosus pontis" EXACT [NIF_GrossAnatomy:birnlex_905] synonym: "substantia ferruginea" EXACT [NIF_GrossAnatomy:birnlex_905] synonym: "blue nucleus" EXACT [NIF_GrossAnatomy:birnlex_905] synonym: "locus cinereus" RELATED [BTO:0001408] xref: BTO:0001408 xref: FMA:72478 ! Locus ceruleus xref: GAID:577 ! locus coeruleu xref: MA:0001017 ! locus coeruleus xref: NIF_GrossAnatomy:birnlex_905 ! Locus ceruleus xref: TAO:0000539 ! locus coeruleus xref: ZFA:0000539 ! locus coeruleus xref: EFO:0001963 ! locus coeruleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Gray709.png/200px-Gray709.png xref: MESH:A08.186.211.132.659.473 ! locus coeruleu xref: ABA:LC ! Locus ceruleus xref: BM:Pons-LC ! locus coeruleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0000988 ! pons relationship: capable_of GO:0048243 ! norepinephrine secretion relationship: spatially_disjoint_from UBERON:0003004 {source="ABA"} ! median raphe nucleus relationship: spatially_disjoint_from UBERON:0002267 {source="ABA"} ! laterodorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002047 {source="ABA"} ! pontine raphe nucleus relationship: spatially_disjoint_from UBERON:0002587 {source="ABA"} ! nucleus subceruleus synonym: "nucleus caeruleus" EXACT LATIN [FMA:TA, FMA:72478] xref: SCTID:369016004 ! Entire locus ceruleus xref: ncithesaurus:Locus_Coeruleus ! locus coeruleus xref: UMLS:C0023951 [Term] id: UBERON:0010125 name: future superior salivatory nucleus is_a: UBERON:0002020 ! gray matter of neuraxis intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: develops_into UBERON:0002149 ! superior salivatory nucleus xref: EHDAA2:0004644 ! future superior salivatory nucleus def: "A gray matter of neuraxis that develops_into a superior salivatory nucleus." [OBOL:automatic] [Term] id: UBERON:0002149 name: superior salivatory nucleus def: "visceromotor cranial nerve nucleus located in the pontine tegmentum." [Wikipedia:Superior_salivatory_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "superior salivary nucleus" EXACT [GO:0021753] xref: FMA:72482 ! Superior salivatory nucleus xref: MA:0001027 ! superior salivatory nucleus xref: NIF_GrossAnatomy:birnlex_1131 ! Superior salivatory nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Gray788.png/200px-Gray788.png xref: ABA:SSN ! Superior salivatory nucleus is_a: UBERON:0004133 ! salivatory nucleus is_a: UBERON:0000126 ! cranial nerve nucleus relationship: part_of UBERON:0003023 ! pontine tegmentum relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus xref: SCTID:369028007 ! Entire superior salivary nucleus xref: EHDAA2:0004646 ! superior salivatory nucleus relationship: immediate_transformation_of UBERON:0010125 {evidence="definitional"} ! future superior salivatory nucleus [Term] id: UBERON:0002153 alt_id: UBERON:0008997 name: fastigial nucleus def: "The fastigial nucleus or nucleus fastigii refers specifically to the concentration of gray matter nearest to the middle line at the anterior end of the superior vermis, and immediately over the roof of the fourth ventricle, from which it is separated by a thin layer of white matter. It is smaller than the nucleus dentatus, but somewhat larger than the nucleus emboliformis and nucleus globosus, the other two independent centers of gray matter in the cerebellum. [WP,unvetted]." [Wikipedia:Fastigial_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "medial (fastigial) nucleus" EXACT [] synonym: "medial cerebellar nucleus" EXACT [] synonym: "roof nucleus-1" EXACT [] synonym: "nucleus fastigii" EXACT [BTO:0003839] xref: FMA:72537 ! Fastigial nucleus xref: MA:0001009 ! medial cerebellar nucleus xref: NIF_GrossAnatomy:birnlex_1146 ! Fastigial nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/23/Gray707.png/200px-Gray707.png xref: ABA:FN ! Fastigial nucleus xref: BM:CB-CBM ! medial nucleus of cerebellum xref: SCTID:279224002 ! Nucleus fastigii xref: BTO:0003839 ! nucleus fastigii is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002130 ! cerebellar nuclear complex relationship: spatially_disjoint_from UBERON:0002132 {source="ABA"} ! dentate nucleus synonym: "nucleus fastigii" RELATED LATIN [Wikipedia:Fastigial_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/2/23/Gray707.png xref: VHOG:0001699 ! fastigial nucleus property_value: homology_notes "One or more deep cerebellar nuclei appear in agnathans, sharks, ropefishes, lungfishes, Latimeria, and amphibians. Reptiles have two nuclei (a medial and a lateral), and birds and mammals have three nuclei (a medial, a lateral, and an interposed nucleus). The medial nucleus of mammals is known as the fastigial nucleus, and the lateral nucleus is known as the dentate nucleus.[well established][VHOG]" xsd:string {external_class="VHOG:0001699", ontology="VHOG", source="ISBN:978-0471210054 Butler AB\, Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.260-261", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006331 ! brainstem nucleus name: brainstem nucleus xref: MA:0000821 ! brainstem nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002298 ! brainstem def: "A nucleus of brain that is part of a brainstem." [OBOL:automatic] [Term] id: UBERON:0002155 name: gigantocellular nucleus def: "The gigantocellular nucleus, as the name indicates, is mainly composed of the so called giant neuronal cells. This nucleus has been known to innervate the caudal hypoglossal nucleus, and responds to glutamateric stimuli. The gigantocellular nucleus excites the hypoglossal nucleus, and can play a role in the actions of the said nerve . This nucleus receives connections from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus. Retrograde studies have shown that the deep mesencephalic reticular formation and oral pontine reticular nucleus project to the nucleus gigantocellularis. The dorsal rostral section of the nucleus reticularis gigantocellularis is also involved mediating in expiration (or out-breathing) along with the parvocellular nucleus. [WP,unvetted]." [Wikipedia:Gigantocellular_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "gigantocellular reticular nucleus" EXACT [] xref: FMA:72576 ! Gigantocellular nucleus xref: MA:0001037 ! gigantocellular reticular nucleus xref: NIF_GrossAnatomy:nlx_anat_1005001 ! Nucleus gigantocellularis xref: ABA:GRN ! Gigantocellular reticular nucleus is_a: UBERON:0006331 ! brainstem nucleus relationship: part_of UBERON:0001896 ! medulla oblongata relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus synonym: "nucleus gigantocellularis" EXACT LATIN [FMA:TA, FMA:72576] [Term] id: UBERON:0002160 name: nucleus prepositus comment: This class was created automatically from a combination of ontologies synonym: "nucleus prepositus hypoglossus" RELATED [] synonym: "prepositus hypoglossal nucleus" EXACT [] synonym: "prepositus nucleus" EXACT [] synonym: "nucleus praepositus" EXACT [NIF_GrossAnatomy:birnlex_2652] xref: FMA:72596 ! Nucleus prepositus xref: MA:0001023 ! prepositus hypoglossal nucleus xref: NIF_GrossAnatomy:birnlex_2652 ! Nucleus prepositus xref: ABA:PRP ! Nucleus prepositus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0000988 ! pons relationship: spatially_disjoint_from UBERON:0002881 {source="ABA"} ! sublingual nucleus xref: SCTID:369078009 ! Entire nucleus prepositus [Term] id: UBERON:0002161 name: gracile nucleus def: "Located in the medulla oblongata, the gracile nucleus is one of the dorsal column nuclei that participate in the sensation of fine touch and proprioception of the lower body (legs and trunk). It contains second-order neurons of the dorsal column-medial lemniscus system, which receive inputs from sensory neurons of the dorsal root ganglia and send axons that synapse in the thalamus. The neurons contained within the nucleus form a visible bump called the gracile tubercle on the posterior side of the closed medulla at the floor of the fourth ventricle. The gracile nucleus and fasciculus carry epicritic, kinesthetic, and conscious proprioceptive information from the lower part of the body (below the level of T6 in the spinal cord). The counterpart to the gracile nucleus and fasciculus is the cuneate nucleus and fasciculus, which carries the same type of information, but from the upper body (above T6, excepting the face and ear - the information from the face and ear is carried by the primary sensory trigeminal nucleus). [WP,unvetted]." [Wikipedia:Gracile_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "Goll's nucleus" EXACT [] synonym: "golls nucleus" EXACT [NIF_GrossAnatomy:birnlex_2643] synonym: "nucleus gracilis" EXACT [NIF_GrossAnatomy:birnlex_2643] xref: FMA:72602 ! Gracile nucleus xref: MA:0001038 ! gracile nucleus xref: NIF_GrossAnatomy:birnlex_2643 ! Gracile nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/df/Gray688.png/200px-Gray688.png xref: EV:0100280 ! nucleus gracilis xref: ABA:GR ! Gracile nucleus xref: BM:Me-Gr ! gracile nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001896 ! medulla oblongata relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception relationship: spatially_disjoint_from UBERON:0002045 {source="ABA"} ! cuneate nucleus xref: SCTID:369071003 ! Entire nucleus gracilis synonym: "nucleus gracilis" RELATED LATIN [Wikipedia:Gracile_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/d/df/Gray688.png [Term] id: UBERON:0002162 name: area postrema def: "A small, rounded eminence on each side of the FOURTH VENTRICLE, which receives nerve fibers from the SOLITARY NUCLEUS , SPINAL CORD, and adjacent areas of the MEDULLA. The area postrema lies outside the BLOOD-BRAIN BARRIER and its functions include acting as an emetic chemoreceptor." [MESH:A08.186.211.132.810.406.286, Wikipedia:Area_postrema] comment: Function notes: vomiting center in humans[WP] subset: uberon_slim subset: vertebrate_core xref: FMA:72607 ! Area postrema xref: GAID:591 ! area postrema xref: MA:0001034 ! area postrema xref: NIF_GrossAnatomy:birnlex_2636 ! Area postrema xref: TAO:0005146 ! area postrema xref: ZFA:0005146 ! area postrema xref: BTO:0003425 ! area postrema xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Gray709.png/200px-Gray709.png xref: MESH:A08.186.211.132.810.406.286 ! area postrema xref: ABA:AP ! Area postrema is_a: UBERON:0010135 {source="MA"} ! sensory circumventricular organ relationship: part_of UBERON:0001896 {source="MA", source="ZFA"} ! medulla oblongata relationship: spatially_disjoint_from UBERON:0002610 {source="ABA"} ! cochlear nuclear complex relationship: spatially_disjoint_from UBERON:0002864 {source="ABA"} ! accessory cuneate nucleus relationship: spatially_disjoint_from UBERON:0007633 {source="ABA"} ! nucleus of trapezoid body relationship: spatially_disjoint_from UBERON:0002126 {source="ABA"} ! solitary tract nuclear complex relationship: spatially_disjoint_from UBERON:0002866 {source="ABA"} ! caudal part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002873 {source="ABA"} ! interpolar part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002591 {source="ABA"} ! oral part of spinal trigeminal nucleus xref: SCTID:369039005 ! Entire area postrema xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png property_value: external_definition "An area of medulla oblongata, outside the blood-brain barrier. The apical terminals of the neurons are, in a strategic location either to monitor the chemical constitution of the plasma or to release neurogenic substances into the general circulation. Ma 1997.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005146", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0002164 name: tectobulbar tract def: "a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain." [GO:0034429] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "tecto-bulbar tract" EXACT [] xref: FMA:72645 ! Tectobulbar tract xref: NIF_GrossAnatomy:birnlex_750 ! Tectobulbar tract xref: TAO:0000446 ! tecto-bulbar tract xref: ZFA:0000446 ! tecto-bulbar tract is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:369265000 ! Entire tectobulbar tract [Term] id: UBERON:0002165 alt_id: UBERON:0006225 name: endocardium def: "The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. Tunica intima which has as its parts the endothelium of endocardium and the fibroelastic connective tissue that surrounds the cavity of a cardiac chamber[FMA]." [Wikipedia:Endocardium, FMA:7280] comment: fixed in GO to reflect FMA. See email to David/Varsha June 18 2010 subset: uberon_slim subset: vertebrate_core synonym: "heart endocardium" EXACT [] synonym: "endocardial tissue" EXACT [EMAPA:17868] xref: BTO:0000387 xref: EFO:0000821 ! endocardium xref: FMA:7280 ! Endocardium xref: GAID:550 ! endocardium xref: galen:Endocardium xref: MAT:0000455 ! endocardium xref: OpenCyc:Mx4rsWA75K1cEduAAADggVaqvw xref: TAO:0001320 ! endocardium xref: XAO:0000066 ! endocardium xref: ZFA:0001320 ! endocardium xref: MA:0000076 ! heart endocardium xref: ncithesaurus:Endocardium ! Endocardium xref: OpenCyc:Mx4rsWA75K1cEduAAADggVaqvw ! endocardium xref: VHOG:0000084 ! heart endocardium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6c/Gray493.png/200px-Gray493.png xref: MESH:A07.541.207 ! endocardium xref: EV:0100021 ! endocardium is_a: UBERON:0002523 ! tunica intima relationship: develops_from UBERON:0003084 ! fused heart primordium relationship: part_of UBERON:0000948 ! heart relationship: has_part UBERON:0001986 ! endothelium xref: AAO:0010408 ! endocardium xref: EMAPA:17868 ! endocardial tissue xref: SCTID:362013006 ! Entire endocardium xref: EHDAA2:0004153 ! endocardium relationship: develops_from UBERON:0007280 {evidence="definitional"} ! presumptive endocardium xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png property_value: external_definition "Part of the heart comprised of thin serous membrane, composed of endothelial tissue, that lines the interior of the heart.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010408", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Layer that lines the lumen of the heart.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001320", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "heart endocardial tissue" RELATED [VHOG:0000084] xref: UMLS:C0014124 [Term] id: UBERON:0008307 name: heart endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000948 ! heart xref: BTO:0004293 ! heart endothelium def: "An endothelium that is part of a heart." [OBOL:automatic] [Term] id: UBERON:0002166 name: endocardium of atrium def: "Endocardium that is part of the atrium." [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "atrial endocardium" EXACT [] synonym: "atrium endocardium" EXACT [] synonym: "Cardiac atria endocardium" EXACT [OBOL:automatic] synonym: "atrium of heart endocardium" EXACT [OBOL:automatic] synonym: "cardiac atrium endocardium" EXACT [OBOL:automatic] synonym: "endocardium of Cardiac atria" EXACT [OBOL:automatic] synonym: "endocardium of atrium of heart" EXACT [OBOL:automatic] synonym: "endocardium of cardiac atrium" EXACT [OBOL:automatic] synonym: "endocardium of heart atrium" EXACT [OBOL:automatic] synonym: "heart atrium endocardium" EXACT [OBOL:automatic] xref: FMA:7284 ! Endocardium of atrium xref: VHOG:0000606 ! atrium endocardium xref: MA:0000077 ! atrium endocardium xref: ZFA:0001614 ! atrial endocardium is_a: UBERON:0002165 ! endocardium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002081 ! cardiac atrium xref: SCTID:192001005 ! Entire endocardium of atrium xref: TAO:0002169 ! atrial endocardium synonym: "atrium endocardial tissue" RELATED [VHOG:0000606] [Term] id: UBERON:0002167 name: right lung def: "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]" [Wikipedia:Right_lung, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: EHDAA:4969 ! right lung xref: FMA:7309 ! Right lung xref: VHOG:0000301 ! right lung xref: MA:0000426 ! right lung xref: ncithesaurus:Right_Lung ! Right Lung xref: OpenCyc:Mx8Ngh4rvgHsHZwpEbGdrcN5Y29ycB4rvVjKy5wpEbGdrcN5Y29ycA ! right lung xref: EHDAA2:0001730 ! right lung xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/32/Gray972.png/200px-Gray972.png xref: EMAPA:17661 ! right lung intersection_of: UBERON:0002048 ! lung intersection_of: in_right_side_of UBERON:0000170 ! pair of lungs xref: SCTID:361967000 ! Entire right lung property_value: homology_notes "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata.[well established][VHOG]" xsd:string {external_class="VHOG:0000301", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.210", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0225706 [Term] id: UBERON:0002168 name: left lung def: "Lung which consists of the left upper lobe and left lower lobe.[FMA]" [Wikipedia:Left_lung, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: EHDAA:4947 ! left lung xref: FMA:7310 ! Left lung xref: VHOG:0000618 ! left lung xref: MA:0000425 ! left lung xref: ncithesaurus:Left_Lung ! Left Lung xref: OpenCyc:Mx8Ngh4rvgIFoJwpEbGdrcN5Y29ycB4rvVjKy5wpEbGdrcN5Y29ycA ! left lung xref: EHDAA2:0000943 ! left lung xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Gray973.png/200px-Gray973.png xref: EMAPA:17653 ! left lung intersection_of: UBERON:0002048 ! lung intersection_of: in_left_side_of UBERON:0000170 ! pair of lungs xref: SCTID:361982005 ! Entire left lung property_value: homology_notes "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata.[well established][VHOG]" xsd:string {external_class="VHOG:0000618", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.210", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0225730 [Term] id: UBERON:0002299 ! alveolus of lung name: alveolus of lung def: "Spherical outcropping of the respiratory bronchioles and primary site of gas exchange with the blood. Alveoli are particular to mammalian lungs. Different structures are involved in gas exchange in other vertebrates[WP]." [Wikipedia:Pulmonary_alveolus] subset: uberon_slim synonym: "alveolus" BROAD [] synonym: "lung alveolus" EXACT [] synonym: "pulmonary alveolus" EXACT [FMA:7318] synonym: "alveoli" RELATED PLURAL [BTO:0000060] synonym: "alveolus pulmonis" EXACT [Wikipedia:Pulmonary_alveolus] xref: BTO:0000060 xref: FMA:7318 ! Pulmonary alveolus xref: VHOG:0001445 ! lung alveolus xref: MA:0000420 ! lung alveolus xref: GAID:349 ! pulmonary alveoli xref: MESH:A04.411.715 ! pulmonary alveoli xref: EV:0100043 ! alveolus (also: UBERON:0003215 'alveolus') xref: EFO:0001985 ! pulmonary alveolus intersection_of: UBERON:0003215 ! alveolus intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0006524 {source="MA"} ! alveolar system relationship: part_of UBERON:0002169 {source="FMA"} ! alveolar sac relationship: only_in_taxon NCBITaxon:40674 {source="PMID:12869615", source="PMID:12625309"} ! Mammalia relationship: site_of GO:0007585 ! respiratory gaseous exchange xref: SCTID:361364000 ! Entire pulmonary alveolus synonym: "alveolus pulmonis" RELATED LATIN [Wikipedia:Pulmonary_alveolus] xref: http://upload.wikimedia.org/wikipedia/commons/4/46/Alveolus_diagram.svg [Term] id: UBERON:0004861 name: right lung alveolus def: "An alveolus that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "alveolus of right lung" EXACT [OBOL:automatic] xref: MA:0001786 ! right lung alveolus xref: EMAPA:19190 ! alveolus of alveolar system of bronchiole of lobar bronchus of accessory lobe (also: UBERON:0002299 'alveolus of lung') xref: EMAPA:19188 ! alveolus of alveolar system of bronchiole of lobar bronchus of caudal lobe (also: UBERON:0002299 'alveolus of lung') xref: EMAPA:19186 ! alveolus of alveolar system of bronchiole of lobar bronchus of cranial lobe (also: UBERON:0002299 'alveolus of lung') xref: EMAPA:19184 ! alveolus of alveolar system of bronchiole of lobar bronchus of middle lobe (also: UBERON:0002299 'alveolus of lung') intersection_of: UBERON:0003215 ! alveolus intersection_of: part_of UBERON:0002167 ! part_of right lung relationship: part_of UBERON:0006526 ! right lung alveolar system xref: ncithesaurus:Right_Lung_Alveolus ! Right Lung Alveolus xref: UMLS:C1709959 [Term] id: UBERON:0004862 name: left lung alveolus def: "An alveolus that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "alveolus of left lung" EXACT [OBOL:automatic] synonym: "alveolus of lobe of left lung" EXACT [OBOL:automatic] xref: MA:0001777 ! left lung alveolus xref: EMAPA:19182 ! alveolus of alveolar system of bronchiole of lobar bronchus of left lung (also: UBERON:0002299 'alveolus of lung') intersection_of: UBERON:0003215 ! alveolus intersection_of: part_of UBERON:0002168 ! part_of left lung relationship: part_of UBERON:0006525 ! left lung alveolar system xref: ncithesaurus:Left_Lung_Alveolus ! Left Lung Alveolus xref: UMLS:C1708673 [Term] id: UBERON:0009058 name: faveolus def: "A bellows-shaped respiratory unit extending from the outer wall of the lung into a central air space." [PMID:12869615] synonym: "lung faveolus" EXACT [] synonym: "faveoli" RELATED PLURAL [] synonym: "edicula" RELATED SENSU [PMID:12625309] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002048 ! lung comment: Dunker (1978) coined the terms ediculae or faveoli to describe the unit structure of the reptilian parenchymal, which are analogous to mammalian alveoli, but are up to 1,000 times larger than alveoli of similar sized mammals[PMID:12625309] [Term] id: UBERON:0008961 ! parabronchus name: parabronchus def: "tertiary bronchus in the avian lung." [http://medical-dictionary.thefreedictionary.com/parabronchi] synonym: "paleopulmonic parabronchus" NARROW [] synonym: "neopulmonic parabronchus" NARROW [] synonym: "parabronchi" RELATED PLURAL [] is_a: UBERON:0002184 {notes="tertiary", source="Kardong"} ! segmental bronchus relationship: part_of UBERON:0002048 ! lung relationship: only_in_taxon NCBITaxon:8782 ! Aves relationship: connected_to UBERON:0009072 ! ventrobronchus relationship: connected_to UBERON:0009073 ! dorsobronchus [Term] id: UBERON:0012086 name: lumen of parabronchus intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0008961 ! parabronchus relationship: part_of UBERON:0008961 ! parabronchus def: "An anatomical cavity that is part of a parabronchus." [OBOL:automatic] [Term] id: UBERON:0012087 name: air capilary def: "An extension of the parabronchus, the walls of which are the site of gas exchange" [ISBN10:0073040584, http://www.vetmed.vt.edu/education/Curriculum/VM8054/Labs/Lab26/Examples/exairves.htm] synonym: "air vesicle" EXACT [] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001004 ! respiratory system relationship: only_in_taxon NCBITaxon:8782 ! Aves relationship: site_of GO:0007585 ! respiratory gaseous exchange relationship: connected_to UBERON:0008961 ! parabronchus [Term] id: UBERON:0009060 ! air sac name: air sac def: "any of the membranous air-filled extensions of the lungs of birds, which increase the efficiency of gaseous exchange in the lungs" [http://www.thefreedictionary.com/air+sac, Wikipedia:Bird_anatomy#Respiratory_system] comment: Three distinct sets of organs perform respiration—the anterior air sacs (interclavicular, cervicals, and anterior thoracics), the lungs, and the posterior air sacs (posterior thoracics and abdominals). The posterior and anterior air sacs, typically nine, expand during inhalation. Air enters the bird via the trachea. Half of the inhaled air enters the posterior air sacs, the other half passes through the lungs and into the anterior air sacs. Air from the anterior air sacs empties directly into the trachea and out the bird's mouth or nares. The posterior air sacs empty their air into the lungs. Air passing through the lungs as the bird exhales is expelled via the trachea. Some taxonomic groups (Passeriformes) possess 7 air sacs, as the clavicular air sacs may interconnect or be fused with the cranial thoracic air sacs[WP] synonym: "psotcranial air sac" RELATED [UBERON:cjm] synonym: "sacci pneumatici" EXACT LATIN [] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001004 ! respiratory system relationship: only_in_taxon NCBITaxon:8782 ! Aves xref: MESH:A13.048 ! air sac xref: http://upload.wikimedia.org/wikipedia/commons/f/f2/BirdRespiration.svg xref: SCTID:49081009 ! Air sacs [Term] id: UBERON:0009948 name: clavicular air sac is_a: UBERON:0009060 ! air sac xref: SCTID:2574004 ! Clavicular air sac [Term] id: UBERON:0009949 name: humeral diverticulum of clavicular air sac is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000976 ! humerus relationship: continuous_with UBERON:0009948 ! clavicular air sac [Term] id: UBERON:0009061 ! anterior air sac name: anterior air sac synonym: "cranial air sac" RELATED [] subset: grouping_class comment: interclavicular, cervicals, & anterior thoracics is_a: UBERON:0009060 ! air sac [Term] id: UBERON:0009062 ! posterior air sac name: posterior air sac synonym: "caudal air sac" RELATED [] subset: grouping_class comment: Half of the inhaled air enters the posterior air sacs. The posterior air sacs empty their air into the lungs. // posterior thoracics & abdominals is_a: UBERON:0009060 ! air sac [Term] id: UBERON:0009063 name: interclavicular air sac comment: Unapaired[Kardong] is_a: UBERON:0009061 ! anterior air sac [Term] id: UBERON:0009064 name: cervical air sac is_a: UBERON:0009061 ! anterior air sac relationship: in_lateral_side_of UBERON:0001004 {source="Kardong"} ! respiratory system xref: SCTID:62426003 ! Cervical air sac [Term] id: UBERON:0009065 name: anterior thoracic air sac synonym: "cranial thoracic air sac" RELATED [] synonym: "cranial thoracic sac" RELATED [] is_a: UBERON:0009061 ! anterior air sac relationship: in_lateral_side_of UBERON:0001004 {source="Kardong"} ! respiratory system [Term] id: UBERON:0009066 name: posterior thoracic air sac synonym: "caudal thoracic air sac" RELATED [] synonym: "caudal thoracic sac" RELATED [] is_a: UBERON:0009062 ! posterior air sac relationship: in_lateral_side_of UBERON:0001004 {source="Kardong"} ! respiratory system xref: SCTID:10576005 ! Caudal thoracic air sac [Term] id: UBERON:0009067 name: abdominal air sac is_a: UBERON:0009062 ! posterior air sac relationship: in_lateral_side_of UBERON:0001004 {source="Kardong"} ! respiratory system xref: SCTID:43701009 ! Abdominal air sac [Term] id: UBERON:0009071 name: mesobronchus synonym: "mesobronchi" RELATED PLURAL [] is_a: UBERON:0002182 {source="Kardong"} ! main bronchus relationship: part_of UBERON:0002048 ! lung relationship: connected_to UBERON:0009060 ! air sac relationship: only_in_taxon NCBITaxon:8782 ! Aves subset: organ_slim [Term] id: UBERON:0009072 name: ventrobronchus synonym: "ventrobronchi" RELATED PLURAL [] is_a: UBERON:0002185 ! bronchus relationship: part_of UBERON:0002048 ! lung relationship: only_in_taxon NCBITaxon:8782 ! Aves relationship: connected_to UBERON:0008961 ! parabronchus subset: organ_slim [Term] id: UBERON:0009073 name: dorsobronchus synonym: "dorsobronchi" RELATED PLURAL [] is_a: UBERON:0002183 {notes="secondary"} ! lobar bronchus relationship: part_of UBERON:0002048 ! lung relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0012088 name: lateroobronchus is_a: UBERON:0002185 ! bronchus relationship: connected_to UBERON:0009066 ! posterior thoracic air sac relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0003706 name: vocal cord def: "Either of two pairs of folds of mucous membrane projecting into the larynx." [Medical_Dictionary:http://medical-dictionary.thefreedictionary.com/] synonym: "Stimmband" RELATED [BTO:0005084] synonym: "Stimmlippe" RELATED [BTO:0005084] synonym: "plica vocalis" RELATED [BTO:0005084] synonym: "vocal band" RELATED [BTO:0005084] synonym: "vocal chord" RELATED [BTO:0005084] synonym: "true vocal cord" EXACT [FMA:55457] synonym: "vocal cord" EXACT [FMA:55457] synonym: "vocal fold" RELATED [GAID:344] xref: BTO:0005084 ! vocal fold xref: FMA:55457 ! Vocal fold xref: GAID:344 ! vocal cord xref: ncithesaurus:Vocal_Cord ! Vocal Cord xref: OpenCyc:Mx4rvVieepwpEbGdrcN5Y29ycA ! vocal cord xref: EMAPA:19181 ! vocal folds xref: MESH:A04.329.364.737 ! vocal cord is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001737 {source="FMA"} ! larynx relationship: part_of UBERON:0002486 {source="BTO"} ! glottis relationship: has_function_in GO:0071625 ! vocalization behavior xref: SCTID:245504003 ! Entire vocal cord relationship: in_lateral_side_of UBERON:0002486 {source="FMA-abduced-lr"} ! glottis xref: UMLS:C0042930 [Term] id: UBERON:0009074 ! syrinx organ name: syrinx organ def: "vocal organ of birds, located at the base of a trachea" [Wikipedia:Syrinx_(bird_anatomy)] synonym: "syrinx" RELATED [] synonym: "avian vocal organ" RELATED [] is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0003126 ! trachea relationship: has_function_in GO:0071625 ! vocalization behavior relationship: only_in_taxon NCBITaxon:8782 ! Aves xref: http://upload.wikimedia.org/wikipedia/commons/8/87/Syrinx.jpg subset: organ_slim [Term] id: UBERON:0009075 name: membrana tympaniformis synonym: "wall of syrinx" EXACT [Wikipedia:Syrinx_(bird_anatomy)] synonym: "syrinx organ wall" EXACT [] intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0009074 ! syrinx organ [Term] id: UBERON:0009076 name: membrana tympaniformis lateralis synonym: "lateral wall of syrinx" EXACT [] is_a: UBERON:0009075 ! membrana tympaniformis [Term] id: UBERON:0009077 name: membrana tympaniformis medialis synonym: "medial wall of syrinx" EXACT [] is_a: UBERON:0009075 ! membrana tympaniformis [Term] id: UBERON:0009078 name: pessulus def: "A delicate bar of cartilage connecting the dorsal and ventral extremities of the first pair of bronchial cartilages in the syrinx of birds" [http://www.encyclo.co.uk/webster/P/64] is_a: UBERON:0007844 ! cartilage element relationship: part_of UBERON:0009074 ! syrinx organ [Term] id: UBERON:0002169 alt_id: UBERON:0008871 name: alveolar sac def: "the small terminal dilation of the alveolar ducts around which the alveoli form pocket-like clusters" [MP:0010902, Wikipedia:Alveolar_sac] subset: uberon_slim synonym: "sacculus alveolaris" EXACT [FMA:7317] synonym: "pulmonary alveolar sac" EXACT [MP:0010902] synonym: "air sac" RELATED [MP:0010902] xref: BTO:0000061 xref: FMA:7317 ! Alveolar sac xref: MA:0000418 ! alveolar sac xref: ncithesaurus:Alveolar_Sac ! Alveolar Sac xref: OpenCyc:Mx4rwCvh75wpEbGdrcN5Y29ycA ! alveolar sac intersection_of: UBERON:0007499 ! epithelial sac intersection_of: part_of UBERON:0008874 ! pulmonary acinus relationship: part_of UBERON:0006524 {source="MA"} ! alveolar system relationship: part_of UBERON:0008874 {source="FMA"} ! pulmonary acinus xref: SCTID:361964007 ! Entire alveolar sac of lung xref: UMLS:C0225691 [Term] id: UBERON:0004821 name: pulmonary alveolus epithelium def: "the epithelial layer of the alveoli[MP]. The layer of cells covering the lining of the tiny air sacs at the end of the bronchioles[BTO]." [MP:0010898, BTO:0003511] synonym: "alveolus epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelial tissue of alveolus" EXACT [OBOL:automatic] synonym: "epithelium of alveolus" EXACT [OBOL:automatic] synonym: "pulmonary alveolar epithelium" EXACT [FMA:63915] synonym: "pulmonary alveolus epithelium" EXACT [MP:0010898] synonym: "alveolus epithelium" EXACT [MA:0001771] xref: MA:0001771 ! alveolus epithelium xref: BTO:0003511 ! alveolar epithelium xref: FMA:63915 ! pulmonary alveolar epithelium is_a: UBERON:0000487 {source="FMA"} ! simple squamous epithelium relationship: part_of UBERON:0004894 {source="FMA"} ! alveolar wall relationship: has_part CL:0002062 {source="FMA"} ! type I pneumocyte intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002299 ! alveolus of lung synonym: "epithelium of pulmonary alveolus" EXACT [FMA:63915] [Term] id: UBERON:0008946 name: lung parenchyma synonym: "respiratory portion of lung" EXACT [FMA:27360] is_a: UBERON:0000353 {source="FMA"} ! parenchyma relationship: part_of UBERON:0002048 {source="FMA"} ! lung intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002048 ! lung xref: FMA:27360 ! Lung parenchyma xref: SCTID:201712001 ! Entire lung parenchyma def: "A parenchyma that is part of a lung." [OBOL:automatic] [Term] id: UBERON:0008870 name: pulmonary alveolar parenchyma def: "the distinguishing cell types of the lung alveolar tissue, including pulmonary epithelial cells (pneumocytes), alveolar capillary endothelial cells, interstitial cells (fibroblasts) and alveolar macrophages" [MP:0010901] is_a: UBERON:0000061 {source="MP"} ! anatomical structure intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002299 ! alveolus of lung [Term] id: UBERON:0010368 name: pulmonary lobule is_a: UBERON:0009911 {source="FMA"} ! lobule relationship: part_of UBERON:0002048 ! lung xref: FMA:75739 ! pulmonary lobule xref: ncithesaurus:Pulmonary_Lobule ! Pulmonary Lobule [Term] id: UBERON:0008874 name: pulmonary acinus def: "the part of the airway consisting of a respiratory bronchiole and all of its branches" [MP:0010911, Wikipedia:Acinus#The_Lungs] synonym: "primary pulmonary lobule" EXACT [FMA:7313] is_a: UBERON:0010368 {source="FMA"} ! pulmonary lobule relationship: part_of UBERON:0002048 ! lung xref: FMA:7313 ! pulmonary acinus xref: SCTID:361365004 ! Entire pulmonary acinus xref: ncithesaurus:Pulmonary_Acinus ! Pulmonary Acinus xref: UMLS:C0225696 [Term] id: UBERON:0010369 name: secondary pulmonary lobule is_a: UBERON:0010368 {source="FMA"} ! pulmonary lobule relationship: part_of UBERON:0008946 {source="FMA"} ! lung parenchyma xref: FMA:7414 ! secondary pulmonary lobule [Term] id: UBERON:0008872 name: pulmonary alveolus wall def: "." [MP:0010903] is_a: UBERON:0000061 {source="MP"} ! anatomical structure relationship: part_of UBERON:0002299 ! alveolus of lung [Term] id: UBERON:0008873 name: alveolar pore def: "the openings in the alveolar septum that permit air flow between adjacent alveoli" [MP:0010904] is_a: UBERON:0000061 {source="MP"} ! anatomical structure relationship: part_of UBERON:0002299 ! alveolus of lung [Term] id: UBERON:0004890 name: right lung accessory lobe def: "A specialized lobe of the right lung that extends to the left side of the organism" [LG:0012619] comment: In mouse this is sometimes divided into intermediate and diaphragmatic lobes[ISBN10:0123813611] // In humans, the right lung typically has 3 lobes (superior, middle, inferior). The lobar fissures are often incomplete, making a connection between two apposed lobes. Conversely, more than the expected number of lobes may be produced by new fissures e.g. the azygous lobe of the lung. The additional lobes are termed 'accessory lobes' -- http://www.gpnotebook.co.uk/simplepage.cfm?ID=1120927803 synonym: "right lung postcaval lobe" EXACT [MA:0000427] synonym: "diaphragmatic lobe" NARROW [ISBN10:0123813611] synonym: "intermediate lobe of right lung" NARROW [ISBN10:0123813611] xref: MA:0000427 ! right lung accessory lobe xref: VHOG:0000831 ! right lung accessory lobe xref: EHDAA2:0001731 ! right lung accessory lobe xref: EMAPA:17981 ! accessory lobe xref: EHDAA:4971 ! accessory lobe of right lung is_a: UBERON:0000101 ! lobe of lung relationship: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0008950 name: azygous lobe of lung is_a: UBERON:0004890 ! right lung accessory lobe def: "The azygous lobe of the lung is an accessory lobe of the right lung. It is rare and usually associated with an abnormality of the azygous vein. It is produced by an aberrant position of the azygous vein near the hilum of the lung. It divides the right superior lobe near the apex of the lung down to the hilum in roughly the median plane. The fissure created, the meso-azygous fissure, is lined by both visceral and parietal pleura. The lobe lies superomedial to the fissure." [http://www.gpnotebook.co.uk, http://www.e-radiography.net/radpath/a/azygoslobe.htm] [Term] id: UBERON:0008955 ! middle lobe of lung name: middle lobe of lung def: "A lobe of the lung that is situated somewhere between an upper lobe and lower lobe." [UBERON:cjm] comment: Taxon notes: mice have 4 right lobes (5 in some schemes), humans have 2, and thus no middle lobe (the lingula is not a lobe) synonym: "lung middle lobe" EXACT [] is_a: UBERON:0000101 ! lobe of lung relationship: posterior_to UBERON:0008948 ! upper lobe of lung relationship: anterior_to UBERON:0008949 ! lower lobe of lung xref: galen:MiddleLobeOfLung ! middle lobe of lung disjoint_from: UBERON:0008949 ! lower lobe of lung disjoint_from: UBERON:0008948 ! upper lobe of lung xref: SCTID:362900002 ! Entire middle lobe of lung [Term] id: UBERON:0002174 name: middle lobe of right lung def: "In the human, the right lung is divided into three lobes (as opposed to two lobes on the left), superior, middle, and inferior, by two interlobular fissures: [WP,unvetted]." [Wikipedia:Middle_lobe_of_right_lung] comment: Called 'middle lobe of lung' in FMA subset: uberon_slim synonym: "intermediate lobe of right lung" EXACT [] synonym: "right lung middle lobe" EXACT [] synonym: "right lung, middle lobe" EXACT [] synonym: "right middle lobe" BROAD [] synonym: "right medial lobe" BROAD [] synonym: "right middle lobe of lung" EXACT [] synonym: "right medial lobe of lung" EXACT [] synonym: "middle lobe of lung" BROAD [FMA:7383] synonym: "lobus medius pulmonis dextri" EXACT LATIN [FMA:TA, FMA:7383] xref: FMA:7383 ! Middle lobe of lung xref: MA:0000430 ! right lung middle lobe xref: galen:MiddleLobeOfRightLung ! middle lobe of right lung xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/32/Gray972.png/200px-Gray972.png xref: EMAPA:17997 ! middle lobe intersection_of: UBERON:0008955 ! middle lobe of lung intersection_of: part_of UBERON:0002167 ! right lung xref: ncithesaurus:Middle_Lobe_of_the_Right_Lung ! Middle Lobe of the Right Lung xref: SCTID:361973004 ! Entire right middle lobe of lung xref: UMLS:C0225757 [Term] id: UBERON:0006518 name: right lung lobe comment: Taxon notes: 4 in mice, divided into 3 in human by two interlobal fissures [ISBN-10:0123813611] synonym: "lobe of the right lung" EXACT [ncithesaurus:Lobe_of_the_Right_Lung] synonym: "lobe of right lung" EXACT [] xref: MA:0001791 ! right lung lobe intersection_of: UBERON:0000101 ! lobe of lung intersection_of: part_of UBERON:0002167 ! right lung xref: ncithesaurus:Lobe_of_the_Right_Lung ! Lobe of the Right Lung xref: SCTID:272654004 ! Entire lobe of right lung def: "A lobe of lung that is part of a right lung." [OBOL:automatic] xref: UMLS:C1285106 [Term] id: UBERON:0008948 name: upper lobe of lung def: "A lobe of the lung that is closest to the head." [UBERON:cjm] comment: Editor notes: the logical definition must have a clause stating position relative to a lower lobe, otherwise a single lobed side (such as the left lobe in the mouse) trivially classifies as an upper lobe synonym: "lobus superior" EXACT [FMA:7334] synonym: "lobus superior pulmonis" EXACT LATIN [FMA:TA] synonym: "superior lobe of lung" EXACT [FMA:7334] synonym: "cranial lobe of lung" EXACT [UBERON:cjm] intersection_of: UBERON:0000101 ! lobe of lung intersection_of: anterior_part_of UBERON:0002048 ! lung intersection_of: anterior_to UBERON:0008949 ! lower lobe of lung xref: FMA:7334 ! upper lobe of lung xref: SCTID:303548008 ! Entire upper lobe of lung xref: ncithesaurus:Lung_Upper_Lobe ! Upper Lobe of the Lung xref: galen:UpperLobeOfLung ! upper lobe of lung xref: UMLS:C0225756 [Term] id: UBERON:0002170 name: upper lobe of right lung def: "The lobe of the right lung that is closest to the head." [UBERON:cjm] synonym: "lobus superior pulmonis dextri" EXACT LATIN [FMA:TA] synonym: "right upper lobe" EXACT [FMA:7333] synonym: "right upper lobe of lung" EXACT [FMA:7333] synonym: "superior lobe of right lung" EXACT [FMA:7333] synonym: "right lung superior lobe" RELATED [MA:0000429] synonym: "right lung cranial lobe" EXACT [MA:0000429] synonym: "right cranial lobe of lung" EXACT [] synonym: "upper lobe of right lung" EXACT [galen:UpperLobeOfRightLung] xref: FMA:7333 ! Upper lobe of right lung xref: VHOG:0000859 ! right lung cranial lobe xref: MA:0000429 ! right lung cranial lobe xref: galen:UpperLobeOfRightLung ! upper lobe of right lung xref: EHDAA2:0001747 ! right lung cranial lobe xref: EMAPA:17991 ! cranial lobe xref: EHDAA:4987 ! cranial lobe of right lung is_a: UBERON:0008948 {source="FMA"} ! upper lobe of lung intersection_of: UBERON:0008948 ! upper lobe of lung intersection_of: part_of UBERON:0002167 ! right lung xref: ncithesaurus:Upper_Lobe_of_the_Right_Lung ! Upper Lobe of the Right Lung xref: SCTID:361969002 ! Entire right upper lobe of lung xref: UMLS:C1261074 [Term] id: UBERON:0008951 name: left lung lobe comment: Taxon notes: 1 in mice, divided into 2 in human by a single interlobar fissure, the oblqiue fissure [ISBN-10:0123813611] xref: EHDAA:2981 ! left lobe synonym: "lobe of the left lung" EXACT [] synonym: "lobe of left lung" EXACT [] intersection_of: UBERON:0000101 ! lobe of lung intersection_of: part_of UBERON:0002168 ! left lung xref: SCTID:272655003 ! Entire lobe of left lung xref: ncithesaurus:Lobe_of_the_Left_Lung ! Lobe of the Left Lung def: "A lobe of lung that is part of a left lung." [OBOL:automatic] xref: UMLS:C1285107 [Term] id: UBERON:0008952 name: upper lobe of left lung def: "The lobe of the left lung that is closest to the head." [UBERON:cjm] synonym: "left upper lobe" EXACT [FMA:7370] synonym: "left upper lobe of lung" EXACT [FMA:7370] synonym: "lobus superior pulmonis sinistri" EXACT LATIN [FMA:TA] synonym: "superior lobe of left lung" EXACT [FMA:7370] synonym: "left lung cranial lobe" EXACT [EHDAA2:0000953] is_a: UBERON:0008948 {source="FMA"} ! upper lobe of lung intersection_of: UBERON:0008948 ! upper lobe of lung intersection_of: part_of UBERON:0002168 ! left lung relationship: never_in_taxon NCBITaxon:10088 {source="ISBN-10:0123813611"} ! Mus xref: FMA:7370 ! upper lobe of left lung xref: EHDAA2:0000953 ! left lung cranial lobe xref: EHDAA:4957 ! cranial lobe xref: SCTID:361984006 ! Entire left upper lobe of lung xref: ncithesaurus:Upper_Lobe_of_the_Left_Lung ! Upper Lobe of the Left Lung xref: galen:UpperLobeOfLeftLung ! upper lobe of left lung xref: UMLS:C1261076 [Term] id: UBERON:0008949 name: lower lobe of lung comment: Editor notes: defining lobes spatially across species is_a: UBERON:0000101 ! lobe of lung relationship: posterior_part_of UBERON:0002048 ! lung synonym: "lobus inferior" EXACT [UBERON:cjm] synonym: "lobus inferior pulmonis" EXACT [UBERON:cjm] synonym: "inferior lobe of lung" EXACT [UBERON:cjm] xref: FMA:7335 ! lower lobe of lung xref: SCTID:303549000 ! Entire lower lobe of lung xref: ncithesaurus:Lung_Lower_Lobe ! Lower Lobe of the Lung xref: galen:LowerLobeOfLung ! lower lobe of lung xref: UMLS:C0225758 [Term] id: UBERON:0002171 name: lower lobe of right lung def: "The lobe of the right lung that is furtherst from the head." [UBERON:cjm] synonym: "lobus inferior pulmonis dextri" EXACT LATIN [FMA:TA, FMA:7337] synonym: "inferior lobe of right lung" EXACT [FMA:7337] synonym: "right lower lobe" EXACT [FMA:7337] synonym: "right lower lobe of lung" EXACT [FMA:7337] synonym: "right lung caudal lobe" RELATED [MA:0000428] synonym: "right lung inferior lobe" RELATED [MA:0000428] synonym: "right caudal lobe of lung" EXACT [] synonym: "lower lobe of right lung" EXACT [galen:LowerLobeOfRightLung] xref: FMA:7337 ! Lower lobe of right lung xref: VHOG:0000857 ! right lung caudal lobe xref: MA:0000428 ! right lung caudal lobe xref: galen:LowerLobeOfRightLung ! lower lobe of right lung xref: EHDAA2:0001740 ! right lung caudal lobe xref: EMAPA:17986 ! caudal lobe xref: EHDAA:4979 ! caudal lobe of right lung is_a: UBERON:0008949 {source="FMA"} ! lower lobe of lung intersection_of: UBERON:0008949 ! lower lobe of lung intersection_of: part_of UBERON:0002167 ! right lung xref: ncithesaurus:Lower_Lobe_of_the_Right_Lung ! Lower Lobe of the Right Lung xref: SCTID:361976007 ! Entire right lower lobe of lung xref: UMLS:C1261075 [Term] id: UBERON:0008953 name: lower lobe of left lung synonym: "inferior lobe of left lung" EXACT [FMA:7371] synonym: "left lower lobe" EXACT [FMA:7371] synonym: "left lower lobe of lung" EXACT [FMA:7371] synonym: "lobus inferior (pulmo sinister)" EXACT [FMA:7371] synonym: "lobus inferior pulmonis sinistri" EXACT LATIN [FMA:TA] synonym: "left lung caudal lobe" EXACT [EHDAA2:0000945] is_a: UBERON:0008949 {source="FMA"} ! lower lobe of lung intersection_of: UBERON:0008949 ! lower lobe of lung intersection_of: part_of UBERON:0002168 ! left lung relationship: never_in_taxon NCBITaxon:10088 {source="ISBN-10:0123813611"} ! Mus xref: FMA:7371 ! lower lobe of left lung xref: EHDAA2:0000945 ! left lung caudal lobe xref: EHDAA:4949 ! caudal lobe xref: SCTID:361989001 ! Entire left lower lobe of lung xref: ncithesaurus:Lower_Lobe_of_the_Left_Lung ! Lower Lobe of the Left Lung xref: galen:LowerLobeOfLeftLung ! lower lobe of left lung def: "A lower lobe of lung that is part of a left lung." [OBOL:automatic] xref: UMLS:C1261077 [Term] id: UBERON:0008954 name: lingula of left lung def: "Anterioinferior portion of left upper lung lobe" [ISBN-10:0123813611, Wikipedia:Lingula_of_left_lung] comment: the lingula of the left lung in humans is not normally considered a true lobe. AO notes: in Galen, it is a middle lobe synonym: "left pulmonary lingula" EXACT [FMA:7433] synonym: "lingula of lung" EXACT [FMA:7433] synonym: "lingula of the lung" EXACT [] synonym: "middle lobe of left lung" RELATED [galen:MiddleLobeOfLeftLung] is_a: UBERON:0000063 {source="FMA"} ! organ segment relationship: part_of UBERON:0008952 {source="ISBN-10:0123813611"} ! upper lobe of left lung relationship: never_in_taxon NCBITaxon:10088 {source="ISBN-10:0123813611"} ! Mus xref: FMA:7433 ! lingula of left lung xref: galen:MiddleLobeOfLeftLung ! middle lobe of left lung xref: SCTID:184916009 ! Entire lingula of left lung xref: ncithesaurus:Lingula ! Lingula of the Lung xref: UMLS:C0225740 [Term] id: UBERON:0002172 name: alveolar atrium synonym: "atrium alveolare" EXACT [] synonym: "atrium of alveolus" EXACT [] synonym: "alveolus of lung atrium" EXACT [OBOL:automatic] synonym: "atrium of alveolus of lung" EXACT [OBOL:automatic] synonym: "atrium of lung alveolus" EXACT [OBOL:automatic] synonym: "lung alveolus atrium" EXACT [OBOL:automatic] xref: FMA:7340 ! Alveolar atrium xref: MA:0000419 ! alveolar atrium is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002299 ! alveolus of lung xref: SCTID:201806004 ! Entire atrium of alveolus [Term] id: UBERON:0003536 name: right lung alveolar duct def: "An alveolar duct that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "alveolar duct of right lung" EXACT [OBOL:automatic] xref: MA:0001785 ! right lung alveolar duct xref: ncithesaurus:Right_Lung_Alveolar_Duct ! Right Lung Alveolar Duct xref: EMAPA:19191 ! alveolar duct of alveolar system of bronchiole of lobar bronchus of accessory lobe (also: UBERON:0002173 'alveolar duct') xref: EMAPA:19189 ! alveolar duct of alveolar system of bronchiole of lobar bronchus of caudal lobe (also: UBERON:0002173 'alveolar duct') xref: EMAPA:19187 ! alveolar duct of alveolar system of bronchiole of lobar bronchus of cranial lobe (also: UBERON:0002173 'alveolar duct') xref: EMAPA:19185 ! alveolar duct of alveolar system of bronchiole of lobar bronchus of middle lobe (also: UBERON:0002173 'alveolar duct') intersection_of: UBERON:0002173 ! alveolar duct intersection_of: part_of UBERON:0002167 ! right lung relationship: part_of UBERON:0006526 ! right lung alveolar system xref: UMLS:C1709958 [Term] id: UBERON:0003537 name: left lung alveolar duct def: "An alveolar duct that is part of a left lung [Automatically generated definition]." [OBOL:automatic] comment: Mice have 1 left lobe synonym: "alveolar duct of left lung" EXACT [OBOL:automatic] xref: MA:0001776 ! left lung alveolar duct xref: ncithesaurus:Left_Lung_Alveolar_Duct ! Left Lung Alveolar Duct xref: EMAPA:19183 ! alveolar duct of alveolar system of bronchiole of lobar bronchus of left lung (also: UBERON:0002173 'alveolar duct') intersection_of: UBERON:0002173 ! alveolar duct intersection_of: part_of UBERON:0002168 ! left lung relationship: part_of UBERON:0006525 ! left lung alveolar system xref: UMLS:C1708672 [Term] id: UBERON:0004903 name: bronchoalveolar duct junction def: "A branch point connecting the respiratory bronchioles to the alveolar ducts[MP]." [MP:0004390] is_a: UBERON:0007651 ! anatomical junction relationship: connects UBERON:0002188 ! respiratory bronchiole relationship: connects UBERON:0002173 ! alveolar duct [Term] id: UBERON:0002175 name: intermediolateral nucleus def: "The intermediolateral nucleus is a region of gray matter found in Rexed lamina VII of the spinal column. Rexed Lamina VII contains several well defined nuclei including the nucleus dorsalis, the intermediolateral cell column (lateral gray horn), and the sacral autonomic nucleus. It extends from the first thoracic through the third lumbar segment, and contains the autonomic motor neurons that give rise to the preganglionic fibers of the sympathetic system. [WP,unvetted]." [Wikipedia:Intermediolateral_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "intermediolateral nucleus of spinal cord" EXACT [] synonym: "spinal cord intermediolateral nucleus" EXACT [] xref: FMA:73915 ! Intermediolateral nucleus xref: MA:0002753 ! spinal cord intermediolateral nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Medulla_spinalis_-_Substantia_grisea_-_English.svg/200px-Medulla_spinalis_-_Substantia_grisea_-_English.svg.png is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002240 ! spinal cord synonym: "nucleus intermediolateralis medullae spinalis" EXACT LATIN [FMA:TA, FMA:73915] synonym: "nucleus intermediolateralis medullae spinalis" RELATED LATIN [Wikipedia:Intermediolateral_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Medulla_spinalis_-_Substantia_grisea_-_English.svg [Term] id: UBERON:0002176 name: lateral cervical nucleus comment: This class was created automatically from a combination of ontologies xref: FMA:73921 ! Lateral cervical nucleus xref: MA:0002755 ! lateral cervical nucleus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002256 ! dorsal horn of spinal cord [Term] id: UBERON:0002177 name: right main bronchus def: "The main bronchus on the right side." [Wikipedia:Right_main_bronchus, UBERON:cjm] comment: Divides into 3 lobar bronchi in humans[ISBN10:0123813611] subset: uberon_slim synonym: "right bronchus" EXACT [] synonym: "right principal bronchus" EXACT [Wikipedia:Right_main_bronchus] synonym: "right primary bronchus" EXACT [Wikipedia:Right_main_bronchus] xref: FMA:7395 ! Right main bronchus xref: MA:0001849 ! right main bronchus xref: ncithesaurus:Right_Main_Bronchus ! Right Main Bronchus xref: OpenCyc:Mx8Ngh4rvgHsHZwpEbGdrcN5Y29ycB4rvoIuvJwpEbGdrcN5Y29ycA ! right main bronchus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Illu_conducting_passages.jpg/200px-Illu_conducting_passages.jpg intersection_of: UBERON:0002182 ! main bronchus intersection_of: continuous_with UBERON:0006518 ! right lung lobe xref: SCTID:361955002 ! Entire right main bronchus synonym: "bronchus principalis dexter" RELATED LATIN [Wikipedia:Right_main_bronchus] xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg xref: UMLS:C0225608 [Term] id: UBERON:0002178 name: left main bronchus def: "The main bronchus on the left side." [Wikipedia:Left_main_bronchus] comment: Divides into 2 lobar bronchi in humans[ISBN10:0123813611] subset: uberon_slim synonym: "left bronchus" EXACT [] synonym: "left primary bronchus" EXACT [Wikipedia:Left_main_bronchus] synonym: "left principal bronchus" EXACT [Wikipedia:Left_main_bronchus] xref: FMA:7396 ! Left main bronchus xref: MA:0001843 ! left main bronchus xref: ncithesaurus:Left_Main_Bronchus ! Left Main Bronchus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c3/Illu_conducting_passages.jpg/200px-Illu_conducting_passages.jpg intersection_of: UBERON:0002182 ! main bronchus intersection_of: continuous_with UBERON:0008951 ! left lung lobe xref: SCTID:361959008 ! Entire left main bronchus synonym: "bronchus principalis sinister" RELATED LATIN [Wikipedia:Left_main_bronchus] xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg xref: UMLS:C0225630 [Term] id: UBERON:0004885 name: hilum alt_id: UBERON:0004460 def: "An anatomical cavity, depression or pit where structures are attached." [Wikipedia:Hilum_of_kidney_of_lung_of_lymph_node] comment: AO notes: Galen and NCITA refer to the generic structure synonym: "hilus" EXACT [Wikipedia:Hilum] xref: FMA:57836 ! Hilum is_a: UBERON:0000161 ! orifice xref: ncithesaurus:Hilum ! Hilum xref: galen:Hilum xref: UMLS:C0929176 [Term] id: UBERON:0008716 name: hilum of kidney synonym: "renal hilum" EXACT [FMA:15610] intersection_of: UBERON:0004885 ! hilum intersection_of: part_of UBERON:0002113 ! kidney xref: FMA:15610 ! hilum of kidney xref: galen:HilumOfKidney ! hilum of kidney xref: SCTID:279370006 ! Entire hilum of kidney xref: ncithesaurus:Hilar_Area_of_the_Kidney ! hilar area of the kidney def: "A hilum that is part of a kidney." [OBOL:automatic] xref: UMLS:C0227608 [Term] id: UBERON:0008332 name: hilum of neuraxis synonym: "neuraxis hilum" EXACT [FMA:83871] is_a: UBERON:0002316 ! white matter of neuraxis xref: FMA:83871 ! hilum of neuraxis [Term] id: UBERON:0008333 name: hilum of inferior olivary complex def: "The white core of the inferior olivary nucleus of the medulla oblongata, most prominent medially." [Dorlands_Medical_Dictionary:MerckSource] synonym: "hilum nuclei olivaris caudalis" RELATED [BTO:0002300] synonym: "hilum of caudal olivary nucleus" RELATED [BTO:0002300] synonym: "hilum of inferior olivary nucleus" RELATED [BTO:0002300] synonym: "hilum nuclei olivaris inferioris" EXACT LATIN [FMA:TA] synonym: "hilum of inferior olivary nucleus" EXACT [FMA:72612] synonym: "inferior olivary hilum" EXACT [FMA:72612] synonym: "inferior olive hilum" EXACT [FMA:72612] is_a: UBERON:0008332 {source="FMA"} ! hilum of neuraxis relationship: part_of UBERON:0001896 {source="FMA"} ! medulla oblongata relationship: part_of UBERON:0007244 {source="BTO"} ! inferior olivary nucleus xref: BTO:0002300 ! hilum nuclei olivaris inferioris xref: FMA:72612 ! hilum of inferior olivary complex [Term] id: UBERON:0004886 name: lung hilus def: "A depression on the surface of the lung where the bronchus, blood vessels and nerves enter." [GOC:lung_mtg, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] synonym: "pulmonary hilum" EXACT [FMA:7330] synonym: "hilum of lung" EXACT [] synonym: "hilus of lung" EXACT [OBOL:automatic] synonym: "lung hilum" EXACT [OBOL:automatic] synonym: "pulmonary hilus" EXACT [OBOL:automatic] xref: FMA:7330 ! pulmonary hilum intersection_of: UBERON:0004885 ! hilum intersection_of: part_of UBERON:0002048 ! lung synonym: "hilum pulmonis" EXACT LATIN [FMA:TA, FMA:7330] xref: SCTID:264017007 ! Entire hilum of lung xref: ncithesaurus:Hilar_Area_of_the_Lung ! hilar area of the lung xref: UMLS:C0225701 [Term] id: UBERON:0004887 name: left lung hilus def: "A lung hilus that is part of the left lung." [OBOL:automatic] synonym: "left pulmonary hilum" EXACT [FMA:9751] synonym: "hilum of left lung" EXACT [] synonym: "hilus of left lung" EXACT [OBOL:automatic] synonym: "left lung hilum" EXACT [OBOL:automatic] synonym: "left pulmonary hilus" EXACT [OBOL:automatic] xref: FMA:9751 ! left pulmonary hilum xref: EMAPA:17980 ! hilus of left lung xref: EHDAA:4965 ! hilus xref: MA:0001781 ! left lung hilus xref: VHOG:0000483 ! left lung hilus xref: EHDAA2:0000962 ! left lung hilus intersection_of: UBERON:0004886 ! lung hilus intersection_of: part_of UBERON:0002168 ! left lung xref: SCTID:361983000 ! Entire hilum of left lung property_value: external_definition "The part of the left lung that is not covered by pleura and through which blood vessels, bronchi, nerves and lymphatics enter and leave the lung. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000483", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/lung+hilus", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004888 name: right lung hilus def: "A lung hilus that is part of the right lung." [OBOL:automatic] synonym: "right pulmonary hilum" EXACT [FMA:7330] synonym: "hilum of right lung" EXACT [] synonym: "hilus of right lung" EXACT [OBOL:automatic] synonym: "right lung hilum" EXACT [OBOL:automatic] synonym: "right pulmonary hilus" EXACT [OBOL:automatic] xref: EHDAA:4995 ! hilus xref: EMAPA:17996 ! hilus of right lung xref: MA:0001790 ! right lung hilus xref: FMA:7456 ! right pulmonary hilum xref: VHOG:0000482 ! right lung hilus xref: EHDAA2:0001756 ! right lung hilus intersection_of: UBERON:0004886 ! lung hilus intersection_of: part_of UBERON:0002167 ! right lung xref: SCTID:361968005 ! Entire hilum of right lung property_value: external_definition "The part of the right lung that is not covered by pleura and through which blood vessels, bronchi, nerves and lymphatics enter and leave the lung. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000482", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/lung+hilus", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002181 name: substantia gelatinosa def: "Gelatinous-appearing material in the dorsal horn of the spinal cord, consisting chiefly of Golgi type II neurons and some larger nerve cells." [Wikipedia:Central_gelatinous_substance_of_spinal_cord_of_Rolando, MESH:A08.186.854.610.800] subset: uberon_slim synonym: "central gelatinous substance of spinal cord" EXACT [] synonym: "gelatinous substance of posterior horn of spinal cord" EXACT [] synonym: "gelatinous substance of dorsal horn of spinal cord" EXACT [] synonym: "gelatinous substance of Rolando" EXACT [FMA:74019] xref: FMA:74019 ! Substantia gelatinosa xref: GAID:701 ! substantia gelatinosa xref: MA:0001124 ! substantia gelatinosa xref: ncithesaurus:Substantia_Gelatinosa ! Substantia Gelatinosa xref: MESH:A08.186.854.610.800 ! substantia gelatinosa xref: EV:0100318 ! substantia gelatinosa is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002256 ! dorsal horn of spinal cord synonym: "substantia gelatinosa cornu posterioris medullae spinalis" EXACT LATIN [FMA:TA, FMA:74019] xref: UMLS:C0038588 [Term] id: UBERON:0002182 name: main bronchus def: "One of two branches of the trachea." [Wikipedia:Main_bronchus] comment: In humans, histologically identical to trachea. subset: uberon_slim synonym: "bronchus principalis" EXACT [FMA:7405] synonym: "primary bronchus" EXACT [FMA:7405] synonym: "principal bronchus" EXACT [FMA:7405] synonym: "mainstem bronchus" EXACT [] synonym: "proximal bronchus" RELATED [] synonym: "extrapulmonary bronchus" EXACT [ISBN10:0123813611] xref: EHDAA:3072 ! main bronchus xref: FMA:7405 ! Main bronchus xref: VHOG:0000370 ! main bronchus xref: MA:0000438 ! main bronchus xref: ncithesaurus:Main_Bronchus xref: EFO:0000932 ! bronchus (also: UBERON:0002185 'bronchus') xref: OpenCyc:Mx4rvoIuvJwpEbGdrcN5Y29ycA ! main bronchus xref: EHDAA2:0001044 ! main bronchus xref: EMAPA:16849 ! main bronchus is_a: UBERON:0002185 ! bronchus relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium relationship: proximally_connected_to UBERON:0003126 ! trachea relationship: distally_connected_to UBERON:0002183 ! lobar bronchus xref: SCTID:245508000 ! Entire main bronchus subset: organ_slim xref: UMLS:C0024496 [Term] id: UBERON:0012083 name: lumen of primary bronchus synonym: "main bronchial lumen" EXACT [FMA:13116] synonym: "principal bronchial lumen" EXACT [] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0002182 ! main bronchus relationship: part_of UBERON:0002182 ! main bronchus xref: FMA:13116 ! lumen of main bronchus synonym: "lumen of main bronchus" EXACT [FMA:13116] def: "An anatomical cavity that is part of a main bronchus." [OBOL:automatic] [Term] id: UBERON:0002183 name: lobar bronchus def: "The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi[GO]." [Wikipedia:Secondary_bronchus, GO:0060482] comment: Structure notes: They have relatively large lumens that are lined by respiratory epithelium. There is a smooth muscle layer below the epithelium arranged as two ribbons of muscle that spiral in opposite directions. This smooth muscle layer contains seromucous glands. Irregularly arranged plates of hyaline cartilage surround the smooth muscle. These plates give structural support to the bronchus and maintain the patency of the lumen. subset: uberon_slim synonym: "bronchi lobaris" EXACT LATIN [Wikipedia:Secondary_bronchus] synonym: "secondary bronchus" EXACT [Wikipedia:Secondary_bronchus, FMA:7406] synonym: "secondary bronchi" RELATED PLURAL [Wikipedia:Secondary_bronchus] synonym: "lobar bronchi" RELATED PLURAL [Wikipedia:Secondary_bronchus] xref: EHDAA:4955 ! lobar bronchus xref: EHDAA:4963 ! lobar bronchus xref: EHDAA:4977 ! lobar bronchus xref: EHDAA:4985 ! lobar bronchus xref: EHDAA:4993 ! lobar bronchus xref: EHDAA:8175 ! lobar bronchus xref: EHDAA:8187 ! lobar bronchus xref: EHDAA:8203 ! lobar bronchus xref: EHDAA:8213 ! lobar bronchus xref: EHDAA:8225 ! lobar bronchus xref: FMA:7406 ! Lobar bronchus xref: MA:0000437 ! lobar bronchus xref: EMAPA:17998 ! lobar bronchus of middle lobe xref: ncithesaurus:Lobar_Bronchus ! Lobar Bronchus xref: OpenCyc:Mx4rwQMLXJwpEbGdrcN5Y29ycA ! lobar bronchus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/df/Illu_quiz_lung05.jpg/200px-Illu_quiz_lung05.jpg is_a: UBERON:0002185 ! bronchus relationship: distally_connected_to UBERON:0002184 ! segmental bronchus relationship: part_of UBERON:0000101 {source="FMA"} ! lobe of lung xref: SCTID:245509008 ! Entire lobar bronchus subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/d/df/Illu_quiz_lung05.jpg xref: UMLS:C0225653 [Term] id: UBERON:0012084 name: lumen of secondary bronchus synonym: "lobar bronchial lumen" EXACT [FMA:62520] synonym: "secondary bronchial lumen" EXACT [] synonym: "lumen of lobar bronchus" EXACT [FMA:62520] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0002183 ! lobar bronchus relationship: part_of UBERON:0002183 ! lobar bronchus xref: FMA:62520 ! lumen of lobar bronchus def: "An anatomical cavity that is part of a lobar bronchus." [OBOL:automatic] [Term] id: UBERON:0002184 name: segmental bronchus def: "The tertiary bronchi (also known as the segmental bronchi) arise from the secondary bronchi. The respiratory epithelium lining their lumen is surrounded by a layer of smooth muscle. This layer is composed of two ribbons of smooth muscle that spiral in opposite directions. The smooth muscle layer is surrounded by irregular plates of hyaline cartilage which help maintain the patency of the airway. Each of the tertiary bronchi serves a specific bronchopulmonary segment. There are 10 tertiary bronchi in the right lung, and eight in the left. The tertiary bronchi get smaller and divide into primary bronchioles. [WP,unvetted]." [Wikipedia:Segmental_bronchus] subset: uberon_slim synonym: "tertiary bronchus" EXACT [] xref: EHDAA:7043 ! segmental bronchus xref: EHDAA:7049 ! segmental bronchus xref: EHDAA:7058 ! segmental bronchus xref: EHDAA:7064 ! segmental bronchus xref: EHDAA:7070 ! segmental bronchus xref: FMA:7407 ! Segmental bronchus xref: VHOG:0001446 ! segmental bronchus xref: MA:0000439 ! segmental bronchus xref: ncithesaurus:Segmental_Bronchus ! Segmental Bronchus xref: OpenCyc:Mx4rwQGFgZwpEbGdrcN5Y29ycA ! segmental bronchus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/df/Illu_quiz_lung05.jpg/200px-Illu_quiz_lung05.jpg is_a: UBERON:0002185 ! bronchus relationship: part_of UBERON:0000101 {source="FMA"} ! lobe of lung relationship: proximally_connected_to UBERON:0002183 ! lobar bronchus xref: SCTID:245513001 ! Entire segmental bronchus subset: organ_slim xref: UMLS:C0444439 [Term] id: UBERON:0012085 name: lumen of tertiary bronchus synonym: "segmental bronchial lumen" EXACT [FMA:62593] synonym: "lumen of segmental bronchus" EXACT [FMA:62593] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0002184 ! segmental bronchus relationship: part_of UBERON:0002184 ! segmental bronchus xref: FMA:62593 ! lumen of segmental bronchus def: "An anatomical cavity that is part of a segmental bronchus." [OBOL:automatic] [Term] id: UBERON:0002185 name: bronchus def: "A portion of the airway that connects to the lungs[GO]." [Wikipedia:Bronchus] comment: In humans, the main bronchus is histologically identical to trachea; 2ary and 3ary bronchi are not; epithelium becomes simple columnar, goblet cell number decreases, elastic fibers in lamina propria increases, distribution more uniform. Muscular layer between mucosa and submucosa appears. cartilage rings become discontinuous plates connected by fibrous connective tissue subset: uberon_slim synonym: "bronchial trunk" EXACT [FMA:7409] synonym: "bronchi" EXACT PLURAL [] synonym: "bronchial tissue" RELATED [BTO:0001340] xref: BTO:0001340 xref: FMA:7409 ! Bronchus xref: VHOG:0000262 ! bronchus xref: MA:0000436 ! bronchus xref: MAT:0000133 ! bronchus xref: MIAA:0000133 ! bronchus xref: XAO:0000121 ! bronchus xref: ncithesaurus:Bronchus ! Bronchus xref: EFO:0000932 ! bronchus (also: UBERON:0002182 'main bronchus') xref: GAID:346 ! bronchi xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/18/Respiratory_system_complete_numbered.svg/200px-Respiratory_system_complete_numbered.svg.png xref: MESH:A04.411.125 ! bronchi xref: EV:0100041 ! bronchus is_a: UBERON:0001005 ! respiratory airway relationship: part_of UBERON:0007196 ! tracheobronchial tree relationship: located_in UBERON:0002224 ! thoracic cavity xref: SCTID:181215002 ! Entire bronchus subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/1/18/Respiratory_system_complete_numbered.svg property_value: external_definition "Each of the two primary divisions of the trachea leading respectively into the right and the left lung. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000262", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "bronchial" xsd:string xref: UMLS:C0006255 [Term] id: UBERON:0012082 name: bronchial lumen synonym: "bronchial lumen" EXACT [FMA:62646] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0002185 {source="FMA"} ! bronchus relationship: part_of UBERON:0002185 {source="FMA"} ! bronchus xref: FMA:62646 ! lumen of bronchus synonym: "lumen of bronchus" EXACT [FMA:62646] xref: SCTID:199401001 ! Entire bronchial lumen def: "An anatomical cavity that is part of a bronchus." [OBOL:automatic] [Term] id: UBERON:0002186 name: bronchiole def: "the first airway branch that no longer contains cartilage; it is a branch of the bronchus[GO]." [Wikipedia:Bronchiole] comment: Structure notes: lacks submucosa and cartilage plates; they have 3 layers: mucosa, muscular layer and outer layer[ISBN10:0123813611] subset: uberon_slim synonym: "lobular bronchiole" EXACT [FMA:7410] synonym: "bronchiolus" RELATED [BTO:0002375] synonym: "bronchioli" RELATED PLURAL [] xref: EHDAA:8171 ! bronchiole xref: EHDAA:8183 ! bronchiole xref: EHDAA:8199 ! bronchiole xref: EHDAA:8221 ! bronchiole xref: FMA:7410 ! Bronchiole xref: VHOG:0000675 ! bronchiole xref: MA:0000422 ! bronchiole xref: ncithesaurus:Bronchiole ! Bronchiole xref: BTO:0002375 ! bronchiole xref: OpenCyc:Mx4rvl9iDpwpEbGdrcN5Y29ycA ! bronchiole xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Alveoli_diagram.png/200px-Alveoli_diagram.png is_a: UBERON:0003914 {source="EHDAA2-abduced"} ! epithelial tube relationship: part_of UBERON:0007196 {source="FMA"} ! tracheobronchial tree relationship: part_of UBERON:0002048 {source="MA"} ! lung relationship: part_of UBERON:0010368 {source="ncit"} ! pulmonary lobule relationship: branch_of UBERON:0002185 ! bronchus xref: SCTID:278982001 ! Entire lobular bronchiole xref: http://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png property_value: has_relational_adjective "bronchiolar" xsd:string xref: UMLS:C0006270 [Term] id: UBERON:0012067 name: primary bronchiole def: "A bronchiole that arises from a segmental bronchus and does not contain cartilage." [Wikipedia:Bronchiole#Primary_bronchioles, ISBN10:0123813611] is_a: UBERON:0002186 {source="FMA"} ! bronchiole relationship: proximally_connected_to UBERON:0002184 ! segmental bronchus xref: FMA:62510 ! proximal bronchiole synonym: "proximal bronchiole" EXACT [FMA:62510] [Term] id: UBERON:0002187 name: terminal bronchiole def: "A terminal bronchiole is a bronchiole at the end of the conducting zone. At the transition into the respiratory zone, alveoli become present. The terminal bronchiole is the most distal segment of the conducting zone. Each of the terminal bronchioles divides to form respiratory bronchioles which contain a small number of alveoli. Terminal bronchioles are lined with simple cuboidal epithelium containing Clara cells. Terminal bronchioles contain a limited number of ciliated cells and no goblet cells. Clara cells are non-ciliated, rounded protein secreting cells. Their secretions are a nonsticky, proteinaceous compound to maintain the airway in the smallest bronchioles. The secretion, called surfactant, reduces surface tension allowing for bronchioles to expand during inspiration and keeping the bronchioles from collapsing during expiration. Clara cells, a stem cell of the respiratory system, produce enzymes that detoxify substances dissolved in the respiratory fluid. [WP,unvetted]." [Wikipedia:Terminal_bronchiole] subset: uberon_slim synonym: "bronchiolus terminalis" EXACT LATIN [] xref: FMA:7411 ! Terminal bronchiole xref: MA:0000424 ! terminal bronchiole xref: ncithesaurus:Terminal_Bronchiole ! Terminal Bronchiole xref: BTO:0003223 ! terminal bronchiole xref: OpenCyc:Mx4rwS7IU5wpEbGdrcN5Y29ycA ! terminal bronchiole xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Alveoli_diagram.png/200px-Alveoli_diagram.png is_a: UBERON:0002186 ! bronchiole xref: SCTID:278981008 ! Entire terminal bronchiole synonym: "bronchioli terminalis" RELATED LATIN [Wikipedia:Terminal_bronchiole] xref: http://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png xref: UMLS:C0225666 [Term] id: UBERON:0002188 name: respiratory bronchiole def: "A bronchiole that is the first segment of the respiratory zone." [Wikipedia:Respiratory_bronchiole, ISBN10:0123813611] comment: Taxon notes: mice have few or none of these structures, with the terminal bronchioles transitioning directly to the alveolary ducts[ISBN10:0123813611] subset: uberon_slim synonym: "bronchiolus respiratorius" EXACT LATIN [FMA:7412] synonym: "bronchiolus respiratorii" EXACT LATIN [Wikipedia:Respiratory_bronchiole] xref: FMA:7412 ! Respiratory bronchiole xref: MA:0000423 ! respiratory bronchiole xref: ncithesaurus:Respiratory_Bronchiole ! Respiratory Bronchiole xref: BTO:0003222 ! respiratory bronchiole xref: OpenCyc:Mx4rwS6ki5wpEbGdrcN5Y29ycA ! respiratory bronchiole xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Alveoli_diagram.png/200px-Alveoli_diagram.png is_a: UBERON:0002186 ! bronchiole relationship: part_of UBERON:0008874 {source="ISBN10:0123813611"} ! pulmonary acinus relationship: proximally_connected_to UBERON:0002187 ! terminal bronchiole relationship: distally_connected_to UBERON:0002173 ! alveolar duct xref: SCTID:128517006 ! Entire respiratory bronchiole xref: http://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png xref: UMLS:C1261270 [Term] id: UBERON:0002173 name: alveolar duct def: "Alveolar ducts are the tiny end ducts of the branching airways that fill the lungs. Each lung holds approximately 1.5 to 2 million of them. The tubules divide into two or three alveolar sacs at the distal end. They are formed from the confluence openings of several alveoli. Distal terminations of alveolar ducts are atria which then end in alveolar sacs. In human anatomy, respiratory bronchioles exists proximal to the alveolar ducts. The epithelial lining consists of smooth muscle knobs covered by nonciliated, simple cuboidal cells. The smooth muscle constricts under parasympathetic innervation and relax under sympathetic innervation. [WP,unvetted]." [Wikipedia:Alveolar_duct] subset: uberon_slim xref: FMA:7341 ! Alveolar duct xref: MA:0000417 ! alveolar duct xref: OpenCyc:Mx4rvXmfV5wpEbGdrcN5Y29ycA xref: ncithesaurus:Alveolar_Duct ! Alveolar Duct xref: OpenCyc:Mx4rvXmfV5wpEbGdrcN5Y29ycA ! alveolar duct is_a: UBERON:0000058 ! duct relationship: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0006524 ! alveolar system xref: http://upload.wikimedia.org/wikipedia/commons/8/8f/Gray975.png xref: UMLS:C0391892 [Term] id: UBERON:0002189 name: outer cortex of kidney comment: This class was created automatically from a combination of ontologies synonym: "outer renal cortex" EXACT [] xref: FMA:74285 ! Outer cortex of kidney xref: MA:0001649 ! outer renal cortex is_a: UBERON:0001225 ! cortex of kidney synonym: "kidney outer cortex" EXACT [MA:0001649] [Term] id: UBERON:0002190 name: subcutaneous adipose tissue synonym: "fatty layer of subcutaneous tissue" EXACT [FMA:74315] xref: FMA:74315 ! Subcutaneous adipose tissue xref: MA:0000473 ! subcutaneous adipose tissue xref: BTO:0004042 ! subcutaneous adipose tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0002072 ! hypodermis synonym: "panniculus adiposus (tela subcutanea)" EXACT LATIN [FMA:TA, FMA:74315] synonym: "panniculus adiposus telae subcutaneae" EXACT LATIN [FMA:TA, FMA:74315] def: "An adipose tissue that is part of a hypodermis." [OBOL:automatic] [Term] id: UBERON:0007808 name: abdominal adipose tissue def: "Adipose tissue located inside the peritoneal cavity, packed in between internal organs and torso. An excess of visceral fat is known as central obesity, or belly fat, the pot belly or beer belly effect, in which the abdomen protrudes excessively." [BTO:0004041] synonym: "abdominal fat" RELATED [BTO:0004041] synonym: "intra-abdominal fat" RELATED [BTO:0004041] synonym: "organ fat" RELATED [BTO:0004041] synonym: "visceral adipose tissue" RELATED [BTO:0004041] synonym: "visceral fat" RELATED [BTO:0004041] xref: BTO:0004041 ! abdominal adipose tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: located_in UBERON:0001179 ! peritoneal cavity xref: EFO:0003771 ! abdominal fat [Term] id: UBERON:0002191 name: subiculum def: "The subiculum is the most inferior component of the hippocampal formation. It lies between the entorhinal cortex and the CA1 subfield of the hippocampus proper. It receives input from CA1 and entorhinal cortical layer III pyramidal neurons and is the main output of the hippocampus. The pyramidal neurons send projections to the nucleus accumbens, septal nuclei, prefrontal cortex, lateral hypothalamus, nucleus reuniens, mammillary nuclei, entorhinal cortex and amygdala. The pyramidal neurons in the subiculum exhibit transitions between two modes of action potential output: bursting and single spiking. The transitions between these two modes is thought to be important for routing information out of the hippocampus. It is the site responsible for ictal activity in some cases of human epilepsy. It has also been implicated in working memory and drug addiction. [WP,unvetted]." [Wikipedia:Subiculum] comment: ABA:SUB is part of the retrohippocampal region, along with the entorhinal area. this is in the hippocampal formation but not the hippocampal region subset: uberon_slim synonym: "subiculum hippocampi" EXACT [FMA:74414] synonym: "subicular cortex" EXACT [NIF_GrossAnatomy:birnlex_1305] synonym: "gyrus parahippocampalis" RELATED [BTO:0003087] synonym: "subiculum cornu ammonis" RELATED [BTO:0003087] xref: FMA:74414 ! Subiculum xref: MA:0000960 ! subiculum xref: NIF_GrossAnatomy:birnlex_1305 ! Subiculum xref: ncithesaurus:Subiculum ! Subiculum xref: BTO:0003087 ! subiculum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Hippocampus_%28brain%29.jpg/200px-Hippocampus_%28brain%29.jpg xref: ABA:SUB ! Subiculum xref: BM:Tel-Cx-SB ! subiculum is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002421 {source="NIF_GrossAnatomy"} ! hippocampal formation relationship: spatially_disjoint_from UBERON:0002728 {source="ABA"} ! entorhinal area relationship: spatially_disjoint_from UBERON:0004683 {source="ABA"} ! parasubiculum relationship: spatially_disjoint_from UBERON:0001953 {source="ABA"} ! presubiculum xref: SCTID:369097009 ! Entire subiculum hippocampi xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Hippocampus_%28brain%29.jpg property_value: has_relational_adjective "subicular" xsd:string xref: UMLS:C0152316 [Term] id: UBERON:0005412 ! optic fissure name: optic fissure def: "Groove that is in the developing ventral optic cup and through which blood vessels pass to the enclosed mesenchyme[ZFA]. a ventral fissure in the developing optic cup through which blood vessels pass to the enclosed mesenchyme[Free online medical dictionary]." [ZFA:0001284, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3083162&group_id=36855, http://medical-dictionary.thefreedictionary.com/optic+fissure, Wikipedia:Choroid_fissure] comment: As the eye starts to develop, a gap opens on the underside of each eye bud. This gap provides a way for the developing eye to be nourished. This gap, called the optic fissure, has to close before the eye is fully developed. Coloboma is the incomplete closer of the optic fissure subset: vertebrate_core synonym: "choroid fissure" RELATED [ZFA:0001284, XAO:0000474, MA:0001305] synonym: "optic fissures" EXACT PLURAL [ZFA:0001284] synonym: "optic stalk fissure" EXACT [EHDAA2:0001319] xref: TAO:0001284 ! optic fissure xref: ZFA:0001284 ! optic fissure xref: MA:0001305 ! choroid fissure xref: XAO:0000474 ! choroid fissure xref: AAO:0011026 ! choroid fissure xref: ZFA:0001284 ! optic fissure xref: EHDAA:4759 ! choroid fissure xref: RETIRED_EHDAA2:0000249 ! choroid fissure xref: VHOG:0000655 ! choroid fissure xref: EMAPA:17166 ! fissure xref: SCTID:361508004 ! Choroidal fissure xref: EHDAA2:0001319 ! optic stalk fissure xref: http://upload.wikimedia.org/wikipedia/commons/9/98/Gray865.png is_a: UBERON:0006846 {source="ZFA"} ! groove relationship: part_of UBERON:0003072 {source="ZFA"} ! optic cup relationship: located_in UBERON:0003098 {source="EHDAA2"} ! optic stalk property_value: external_definition "A break in the continuity of the optic cup where the two sides of the cup meet.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011026", date_retrieved="2012-06-20", source="ISBN:0815318960"} synonym: "choroid fissure - optic fissure" EXACT [VHOG:0000655] property_value: homology_notes "The folded arrangement of the vertebrate retina and RPE [retinal pigment epithelial] provides an evolutionary explanation for the occurrence of the choroid fissure, as proposed more than a century ago. Early in evolution, before the optic cup invaginated, the axons from retinal ganglion cells would simply have run over the surface of the structure. Hence, one can view the optic nerve as having acted rather like a rope in linking the retina to higher centres: the developing eye cup has simply wrapped around this 'rope', and the developing axons have thereby not needed to penetrate the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0000655", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD\, Collin SP and Pugh EN\, Evolution of the vertebrate eye: opsins\, photoreceptors\, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003098 name: optic stalk def: "The optic vesicles project toward the sides of the head, and the peripheral part of each expands to form a hollow bulb, while the proximal part remains narrow and constitutes the optic stalk. [WP,unvetted]." [Wikipedia:Optic_stalk] subset: uberon_slim subset: vertebrate_core xref: EHDAA:3816 ! optic stalk xref: VHOG:0000223 ! optic stalk xref: TAO:0000137 ! optic stalk xref: XAO:0000475 ! optic stalk xref: ZFA:0000137 ! optic stalk xref: ncithesaurus:Optic_Stalk ! Optic Stalk xref: EHDAA2:0001318 ! optic stalk xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Gray864.png/200px-Gray864.png xref: EMAPA:16678 ! optic stalk is_a: UBERON:0000061 ! anatomical structure relationship: develops_from UBERON:0003072 ! optic cup relationship: part_of UBERON:0001894 ! diencephalon xref: AAO:0011077 ! optic stalk xref: SCTID:308788004 ! Entire optic stalk synonym: "pedunculus opticus" RELATED LATIN [Wikipedia:Optic_stalk] xref: http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png property_value: external_definition "The evagination from the neural tube of the developing embryo which develops the optic cup at its extremity; the stalk persists as the optic nerve. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000223", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/optic+stalk", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup.[well established][VHOG]" xsd:string {external_class="VHOG:0000223", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231107 [Term] id: UBERON:0002194 name: capsule of lymph node def: "Capsule surrounding lymph node composed of connective tissue with some plain muscle fibers. from its internal surface are given off a number of membranous processes or trabeculae, consisting, in man, of connective tissue, with a small admixture of plain muscle fibers; but in many of the lower animals composed almost entirely of involuntary muscle[WP]." [Wikipedia:Lymph_node_capsule] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lymph node capsule" EXACT [] xref: FMA:74604 ! Capsule of lymph node xref: MA:0000739 ! lymph node capsule xref: ncithesaurus:Lymph_Node_Capsule ! Lymph Node Capsule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Lymphknoten_%28Schwein%29.jpg/200px-Lymphknoten_%28Schwein%29.jpg is_a: UBERON:0003893 ! capsule intersection_of: UBERON:0003893 ! capsule intersection_of: surrounds UBERON:0000029 ! lymph node relationship: surrounds UBERON:0000029 ! lymph node relationship: has_part UBERON:0002384 ! connective tissue xref: SCTID:327532004 ! Entire capsule of lymph node xref: UMLS:C0229699 [Term] id: UBERON:0003893 ! capsule name: capsule def: "a cover or envelope partly or wholly surrounding a structure. Examples: egg shell, articular capsules, renal capsules[WP]." [Wikipedia:Capsule_(anatomy)] comment: see also: protective structure surrounding some species of bacteria and fungi. Note that FMA has classes such as Articular capsule that are not subtypes of Capsule (which is undefined in FMA). GO has 'capsule' which is a fungal structure, and 'external encapsulating structure' which is restricted to cells subset: grouping_class xref: FMA:85272 ! Capsule xref: EHDAA:4739 ! capsule xref: EHDAA:9061 ! capsule xref: galen:Capsule ! capsule is_a: UBERON:0000158 ! membranous layer relationship: surrounds UBERON:0000061 ! anatomical structure property_value: has_relational_adjective "capsular" xsd:string [Term] id: UBERON:0005170 name: ovary stratum granulosum subset: vertebrate_core synonym: "membrana granulosa of ovarian follicle" EXACT [FMA:18660] synonym: "granulosa cell layer of ovarian follicle" EXACT [FMA:18660] synonym: "stratum granulosum of ovarian follicle" EXACT [FMA:18660] xref: MA:0001460 ! ovary stratum granulosum xref: FMA:18660 ! membrana granulosa of ovarian follicle xref: ZFA:0001112 ! granulosa cell layer is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0001305 ! ovarian follicle relationship: has_part CL:0000501 {source="FMA"} ! granulosa cell xref: SCTID:258971005 ! Entire stratum granulosum of ovarian follicle xref: TAO:0001112 ! granulosa cell layer synonym: "granulosa cell layer" RELATED [TAO:0001112] xref: EFO:0003628 ! granulosa cell layer [Term] id: UBERON:0002195 name: trabecula of lymph node def: "Membranous process coming from capsule of lymph node[WP]." [Wikipedia:Lymph_node_trabeculae] comment: This class was created automatically from a combination of ontologies synonym: "lymph node trabecula" EXACT [] synonym: "lymph node trabeculum" EXACT [] xref: FMA:74605 ! Trabecula of lymph node xref: MA:0000746 ! lymph node trabeculum xref: ncithesaurus:Lymph_Node_Trabecula ! Lymph Node Trabecula xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/Gray598.png/200px-Gray598.png is_a: UBERON:0000440 ! trabecula relationship: part_of UBERON:0000029 ! lymph node xref: UMLS:C1184179 [Term] id: UBERON:0005356 ! Rathke's pouch name: Rathke's pouch def: "a pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland[MP]. In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system[WP]." [Wikipedia:Rathke's_pouch, MP:0003817] comment: EHDAA2 distinguishes between the adenohypophyseal pouch and it's precursor Rathke's pouch epithelium. Taxon notes: median funnel­-shaped invagination of ectoderm, the nasohypophyseal pouch. It will contribute to the formation of the pituitary gland of the adult lamprey and is homologous to Rathke’s pouch and perhaps to Hatschek 's pit (amphioxus).[http://webs.lander.edu/rsfox/invertebrates/ammocoetes.html] synonym: "pouch of Rathke" EXACT [] synonym: "Rathke pouch" EXACT [] synonym: "pituitary diverticulum" RELATED [MP:0003817] synonym: "Rathke's pocket" RELATED [MP:0003817] synonym: "Rathke's cleft" RELATED [] synonym: "Rathke's cyst" RELATED [] synonym: "craniobuccal pouch" RELATED [] synonym: "craniopharyngeal pouch" RELATED [] synonym: "hypophyseal pouch" RELATED [ISBN10:0073040584] synonym: "nasohypophyseal pouch" RELATED SENSU [http://webs.lander.edu/rsfox/invertebrates/ammocoetes.html] synonym: "hypophyseal diverticulum" RELATED [UBERON:cjm] synonym: "adenohypophysial pouch" NARROW [EHDAA2:0001588] synonym: "Rathkes pouch epithelium" NARROW [EHDAA2:0001473] xref: XAO:0000430 ! Rathke's pouch xref: VHOG:0000674 ! Rathke's pouch xref: EHDAA2:0001588 ! adenohypophysial pouch xref: EMAPA:16574 ! Rathke's pouch of pituitary of gland of stomatodaeum xref: EMAPA:16725 ! Rathke's pouch of pituitary of gland of oral region is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: part_of UBERON:0000033 ! head relationship: develops_from UBERON:0000930 {source="MP"} ! stomodeum relationship: develops_from UBERON:0009122 {source="NBK53175"} ! adenohypophyseal placode relationship: dubious_for_taxon NCBITaxon:7955 ! Danio rerio xref: ncithesaurus:Rathke_s_Pouch ! Rathke Pouch xref: ncithesaurus:Rathke_Pouch_Epithelium ! rathke pouch epithelium xref: AAO:0011094 ! Rathke's pouch xref: SCTID:61127000 ! Fetal Rathke's pouch xref: SCTID:362583008 ! hypophyseal diverticulum property_value: external_definition "A depression that forms in the roof of the mouth of an embryo, anterior to the buccopharyngeal membrane. The walls of the diverticulum develop into the anterior lobe of the pituitary gland. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000674", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/rathke's+pouch", source="http://bgee.unil.ch/"} property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0000674", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1709841 xref: UMLS:C0229548 [Term] id: UBERON:0012287 name: Rathkes pouch epithelium intersection_of: UBERON:0007499 ! epithelial sac intersection_of: part_of UBERON:0005356 ! Rathke's pouch relationship: develops_from UBERON:0009479 {source="EHDAA2"} ! ectoderm of buccopharyngeal membrane relationship: part_of UBERON:0011642 {source="EHDAA2"} ! oral epithelium from ectoderm xref: EHDAA2:0001473 ! Rathkes pouch epithelium xref: EMAPA:25036 ! wall [Term] id: UBERON:0009974 ! lumen of Rathke's pouch name: lumen of Rathke's pouch synonym: "Rathkes pouch invagination" NARROW [EHDAA2:0004138] is_a: UBERON:0005082 {source="EHDAA2"} ! tube lumen intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0005356 ! Rathke's pouch relationship: part_of UBERON:0005356 ! Rathke's pouch relationship: surrounded_by UBERON:0012287 {source="EHDAA2-modified"} ! Rathkes pouch epithelium xref: EHDAA2:0004138 ! Rathkes pouch invagination xref: EMAPA:25037 ! lumen of Rathke's pouch def: "An anatomical cavity that surrounded_by a Rathke's pouch." [OBOL:automatic] [Term] id: UBERON:0009975 name: remnant of lumen of Rathke's pouch comment: Editors note: requires review synonym: "adenohypophysis invagination" RELATED [EHDAA2:0004139] is_a: UBERON:0005082 {source="EHDAA2"} ! tube lumen relationship: part_of UBERON:0002196 ! adenohypophysis relationship: develops_from UBERON:0009974 ! lumen of Rathke's pouch xref: EHDAA2:0004139 ! adenohypophysis invagination [Term] id: UBERON:0006377 ! remnant of Rathke's pouch name: remnant of Rathke's pouch synonym: "hypophyseal cleft" RELATED [MA:0000857] xref: MA:0000857 ! remnant of Rathke's pouch xref: EMAPA:17518 ! remnant of Rathke's pouch is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002196 ! adenohypophysis relationship: develops_from UBERON:0005356 ! Rathke's pouch [Term] id: UBERON:0009122 name: adenohypophyseal placode def: "The adenohypophyseal placode forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary" [http://www.ncbi.nlm.nih.gov/books/NBK53175/] synonym: "pituitary placode" RELATED [ZFA:0001198] comment: Editor notes: consider adding more detailed spatial placement - e.g. oral ectoderm and/or rostal ectoderm. Addtional notes: Fate-mapping studies in amphibian, chick and mouse embryos (Eagleson et al., 1986; 1995; Couly and Le Douarin, 1985; Cobos et al., 2001; Osumi-Yamachita et al., 1994; Kawamura et al., 2002) have shown that the cells contributing to the adenohypophysis develop at the midline of the anterior neural ridge, which delineates the rostral boundary of the neural plate, a region devoid of neural crest. The anterior neural ridge also gives rise to the olfactory placodes and some forebrain tissues including the olfactory bulbs (reviewed in Papalopulu, 1995). Ablation of this region in chick embryos at the 2-4 somite stage confirmed these lineage analyses as it prevented formation of Rathke’s pouch and any further pituitary development (elAmraoui and Dubois, 1993). Upon head folding, the oral ectoderm cells of the adenohypophyseal placode invaginate towards the prospective ventral diencephalon to form Rathke’s pouch, the anlage of the adenohypophysis. Rathke’s pouch starts as an invagination of the oral ectoderm in response to inductive signals from the prospective diencephalon. The region of the diencephalon above the pouch is known as the infundibulum and forms the posterior lobe of the pituitary or neurohypohysis (Figure 3). While in most basal fish and tetrapods the adenohypophyseal anlagen invaginates to form Rathke’s pouch, in teleost fish the adenohypophyseal placode does not invaginate but rather maintains its initial organization forming a solid structure in the head (reviewed in Pogoda and Hammerschmidt; 2009) xref: TAO:0001198 ! adenohypophyseal placode is_a: UBERON:0011814 {source="NBK53175"} ! non-neurogenic ectodermal placode is_a: UBERON:0002546 ! cranial placode relationship: develops_from UBERON:0005497 {source="ZFA"} ! non-neural ectoderm xref: ZFA:0001198 ! adenohypophyseal placode xref: XAO:0004208 ! adenohypophyseal placode xref: EFO:0000229 ! adenohypophyseal placode [Term] id: UBERON:0002196 name: adenohypophysis def: "The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates several physiological processes including stress, growth, and reproduction[WP]. The anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone and proopiomelanocortin. In contrast to mammalian vertebrates, the adenohypophysis remains in a subepithelial position and there exists no equivalent of Rathke's pouch in zebrafish[ZFA]." [Wikipedia:Adenohypophysis, ZFIN:curator] comment: note that BTO may contain an error here. Also note we may need to introduce taxon-specific developmental relationships: "While in most basal fish and tetrapods the adenohypophyseal anlagen invaginates to form Rathke’s pouch, in teleost fish the adenohypophyseal placode does not invaginate but rather maintains its initial organization forming a solid structure in the head"[NBK53175] subset: uberon_slim subset: vertebrate_core synonym: "anterior lobe (hypophysis)" EXACT [] synonym: "anterior lobe of hypophysis" EXACT [] synonym: "anterior lobe of pituitary" EXACT [] synonym: "anterior lobe of pituitary gland" EXACT [] synonym: "anterior pituitary" EXACT [] synonym: "pituitary gland, anterior lobe" EXACT [] synonym: "anterior hypophysis" EXACT [ZFA:0001282] synonym: "anterior pituitary gland" RELATED [BTO:0000040] xref: BTO:0000496 ! anterior lobe xref: BTO:0000040 ! adenohypophysis xref: EFO:0000230 ! adenohypophysis xref: FMA:74627 ! Adenohypophysis xref: VHOG:0000141 ! adenohypophysis xref: MA:0000177 ! adenohypophysis xref: NIF_GrossAnatomy:birnlex_1581 ! Adenohypophysis xref: TAO:0001282 ! adenohypophysis xref: ZFA:0001282 ! adenohypophysis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Gray1181.png/200px-Gray1181.png xref: EMAPA:17514 ! adenohypophysis xref: MESH:A06.407.747.608 ! anterior pituitary gland xref: BM:AHy ! adenohypophysis is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000007 ! pituitary gland relationship: develops_from UBERON:0005356 {gci_relation="part_of", gci_filler="NCBITaxon:32523", source="NBK53175", exception="teleost"} ! Rathke's pouch relationship: develops_from UBERON:0009122 {source="ZFA", source="NBK53175"} ! adenohypophyseal placode relationship: has_part CL:0002312 ! somatotroph relationship: has_part CL:0000295 {source="ZFA"} ! somatotropin secreting cell relationship: has_part CL:0000439 {source="ZFA"} ! prolactin secreting cell relationship: has_part CL:0000467 {source="ZFA"} ! adrenocorticotropic hormone secreting cell relationship: only_in_taxon NCBITaxon:7742 {source="PMID:19084529"} ! Vertebrata synonym: "lobus anterior hypophysis" EXACT LATIN [FMA:TA, FMA:74627] synonym: "lobus anterior (glandula pituitaria)" EXACT LATIN [FMA:TA, FMA:74627] xref: ncithesaurus:Anterior_Lobe_of_the_Pituitary_Gland ! Anterior Lobe of the Pituitary Gland xref: AAO:0010540 ! adenohypophysis xref: SCTID:245532007 ! Entire adenohypophysis xref: EHDAA2:0000109 ! adenohypophysis property_value: external_definition "Region of the pituitary gland derived from the buccal protrusion consisting of three regions.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010540", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone and proopiomelanocortin. In contrast to mamalian vertebrates, the adenohypophysis remains in a subepithelial position and there exists no equivalent of Rathke's pouch in zebrafish. Herzog et al, 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001282", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0000141", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0032008 [Term] id: UBERON:0009861 ! ascidian neural complex name: ascidian neural complex def: "." [PMID:21558186] is_a: UBERON:0002530 ! gland relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009862 name: ascidian cerebral ganglion def: "." [PMID:21558186] comment: the CG appears to be a diencephalic brain. It originates mainly from the posterior sensory vesicle (Takamura 2002; Dufour et al. 2006) and shows endocrine activity. For examples, ascidian genes orthologous to GnRH and OT/VP, which are secreted from the hypothalamus and the NH, respectively, in vertebrates, are expressed in the cortex of the CG, suggesting that the NC is not distinctly compartmentalized as are vertebrate brains (Tsutsui et al. 1998; Kavanaugh et al. 2005; Kawada et al. 2008; Ukena et al. 2008; Kawada et al. 2009). Moreover, PC2 expression in the cortex of the CG supports possible endocrine activity (Sekiguchi et al. 2007). is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0009861 ! ascidian neural complex [Term] id: UBERON:0009863 name: ascidian ciliated funnel def: "." [PMID:21558186] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0009861 ! ascidian neural complex [Term] id: UBERON:0009864 name: ascidian neural gland def: "." [PMID:21558186] comment: assumed to be a pituitary homolog. Current data from the Ciona genome suggests that the ascidian NC, including the CF, is unlikely to be a pituitary-like endocrine gland, while it is necessary to examine other ascidians before drawing a final conclusion [PMID:21558186] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0009861 ! ascidian neural complex relationship: develops_from UBERON:0009718 ! neurohypophyseal duct relationship: homologous_to UBERON:0002196 {source="PMID:21558186"} ! adenohypophysis relationship: only_in_taxon NCBITaxon:7713 ! Ascidiacea [Term] id: UBERON:0007686 name: obsolete Hatschek's pit/nephridium is_obsolete: true [Term] id: UBERON:0009956 name: corpuscle of de Quatrefage def: "A specialised sensory organ located in the subepidermal connective tissue at the rostral end of late larval and adult amphioxus. They consist of between 1 and 4 nerve cells with axons, each with 2 cilia, surrounded by up to 7 sheath cells. The cilia extend into a protrusion of the basal lamina which surrounds each corpuscle. The axonal process contributes to the rostral nerve." [PMID:11523831] synonym: "organ of de Quatrefage" EXACT [] is_a: UBERON:0000020 ! sense organ relationship: only_in_taxon NCBITaxon:7737 {source="PMID:11523831"} ! Branchiostoma [Term] id: UBERON:0009718 ! neurohypophyseal duct name: neurohypophyseal duct def: "Embryonic duct that is the rudiment of cerebral ganglion and and neural gland of adult in the ascidians." [DOI:10.1002/jez.b.21013] comment: Homology: candidate homolog for both neural crest and for the combined olfactory and adenohypophyseal placodes (Burighel et al., 2003; Manni et al., 2004a). Development: During formation of the adult ascidian, the ectodermal neurohypophyseal duct fuses with an evagination of the pharynx to form the neural gland rudiment is_a: UBERON:0000058 ! duct relationship: homologous_to UBERON:0009122 {source="Manni 1999"} ! adenohypophyseal placode relationship: homologous_to UBERON:0002196 {source="PMID:11523831"} ! adenohypophysis relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009957 ! ciliated pit name: ciliated pit synonym: "pre-oral pit" RELATED [] comment: Development: joins with Hatschek’s diverticulum to form Hatschek’s pit in the adult. Location: anterior to the mouth. is_a: UBERON:0006846 ! groove relationship: only_in_taxon NCBITaxon:7737 {source="Wikipedia"} ! Branchiostoma [Term] id: UBERON:0009865 name: Hatschek's pit def: "a deep ciliated fossa on the dorsal midline of the buccal cavity (the region of the gut behind the mouth). Among other things, it secrets mucus which entraps food particles from the water[WP]." [Wikipedia:Hatschek's_pit] is_a: UBERON:0006846 ! groove relationship: only_in_taxon NCBITaxon:7737 {source="Wikipedia"} ! Branchiostoma relationship: capable_of GO:0070254 ! mucus secretion relationship: homologous_to UBERON:0002196 {source="PMID:9636084"} ! adenohypophysis relationship: develops_from UBERON:0009868 ! Hatschek's left diverticulum relationship: develops_from UBERON:0009957 ! ciliated pit [Term] id: UBERON:0009866 name: Hatschek's nephridium def: "an unpaired kidney whose duct opens into the anterior pharynx. It can be seen as a deep ciliated fossa on the dorsal midline of the buccal cavity (mouth). Among other things, it secrets mucus which entraps food particles from the water[WP]." [] is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001008 ! urinary system relationship: only_in_taxon NCBITaxon:7737 {source="Wikipedia"} ! Branchiostoma subset: organ_slim [Term] id: UBERON:0009867 ! Hatschek's diverticulum name: Hatschek's diverticulum relationship: only_in_taxon NCBITaxon:7737 {source="Wikipedia"} ! Branchiostoma is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0008814 ! pharyngeal system [Term] id: UBERON:0009868 ! Hatschek's left diverticulum name: Hatschek's left diverticulum intersection_of: UBERON:0009867 ! Hatschek's diverticulum intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism def: "A Hatschek's diverticulum that is in the left side of a multi-cellular organism." [OBOL:automatic] [Term] id: UBERON:0009869 name: Hatschek's right diverticulum intersection_of: UBERON:0009867 ! Hatschek's diverticulum intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism def: "A Hatschek's diverticulum that is in the right side of a multi-cellular organism." [OBOL:automatic] [Term] id: UBERON:0012473 ! oral cirrus name: oral cirrus def: "Small tentacle-like structure surrounding the mouth; they act as sensory devices and as a filter for the water passing into the body" [Wikipedia:Lancelet#Physical_features] synonym: "oral cirri" EXACT PLURAL [] synonym: "buccal cirri" EXACT PLURAL [] synonym: "buccal cirrus" EXACT [] synonym: "buccal tentacle" EXACT [] synonym: "oral tentacle" EXACT [] synonym: "buccal cillium" RELATED [] synonym: "oral cillium" RELATED [] synonym: "oral cilia" EXACT PLURAL [] synonym: "buccal cilia" EXACT PLURAL [] is_a: UBERON:0000062 ! organ relationship: present_in_taxon NCBITaxon:7737 ! Branchiostoma relationship: adjacent_to UBERON:0000165 ! mouth relationship: never_in_taxon NCBITaxon:40674 ! Mammalia xref: BTO:0001357 ! tentacle [Term] id: UBERON:0013642 name: ring of oral cilia is_a: UBERON:0000062 ! organ relationship: surrounds UBERON:0000165 ! mouth relationship: composed_primarily_of UBERON:0012473 ! oral cirrus [Term] id: UBERON:0013643 name: lophophore def: "A ring of ciliated tentacles surrounding the mouth" [Wikipedia:Lophophore] comment: In the Entoprocta the anus is within the ring of the lophophore is_a: UBERON:0013642 ! ring of oral cilia [Term] id: UBERON:0012474 name: hepatic cecum def: "A ventral evagination extending anteriorly in the mid-portion of the intestine in Amphioxi." [BTO:0002855] comment: Homology notes: may be analagous to liver, Romer says not homologous synonym: "hepatic caecum" EXACT [BTO:0002855] is_a: UBERON:0009854 ! digestive tract diverticulum relationship: part_of UBERON:0000160 {source="BTO"} ! intestine relationship: present_in_taxon NCBITaxon:7737 ! Branchiostoma xref: BTO:0002855 ! hepatic cecum [Term] id: UBERON:0011359 name: urophysis def: "This is a neurosecretory organ rostral to the ampulla caudalis on the ventral surface of the distal end of the spinal cord. Receives axons from caudal neurosecretory nucleus, which contains Dahlgren cells that secrete urotensin I and II, implicated in osmotic regulation, cardiovascular function and reproduction[Butler]." [ISBN10:0471888893] comment: Shares characteristics with neurohypophysis is_a: UBERON:0002368 {source="BTO"} ! endocrine gland relationship: part_of UBERON:0002240 {source="BTO"} ! spinal cord relationship: never_in_taxon NCBITaxon:32523 {source="ISBN10:0471888893"} ! Tetrapoda xref: BTO:0001848 ! urophysis [Term] id: UBERON:0002648 name: anterior median eminence xref: FMA:74870 ! Anterior median eminence xref: NIF_GrossAnatomy:birnlex_1264 ! Anterior median eminence is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002197 ! median eminence of neurohypophysis [Term] id: UBERON:0002652 name: posterior median eminence xref: FMA:74875 ! Posterior median eminence xref: NIF_GrossAnatomy:birnlex_1280 ! Posterior median eminence is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002197 ! median eminence of neurohypophysis [Term] id: UBERON:0002197 name: median eminence of neurohypophysis def: "The median eminence is part of the inferior boundary for the hypothalamus part of the human brain. A small swelling on the tuber cinereum posterior to the infundibulum - atop the pituitary stalk - the median eminence lies in the area roughly bounded on its posterolateral region by the cerebral peduncles, and on its anterolateral region by the optic chiasm. The median eminence is one of the seven areas of the brain devoid of a blood-brain barrier. [WP,unvetted]." [Wikipedia:Median_eminence] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "median eminence" EXACT [] synonym: "median eminence of hypothalamus" EXACT [] synonym: "median eminence of posterior lobe of pituitary gland" EXACT [] synonym: "median eminence of tuber cinereum" EXACT [] xref: EHDAA:7540 ! median eminence xref: FMA:74634 ! Median eminence of neurohypophysis xref: GAID:463 ! median eminence xref: VHOG:0001179 ! median eminence xref: MA:0000859 ! median eminence xref: NIF_GrossAnatomy:birnlex_925 ! Median eminence xref: BTO:0001954 ! median eminence xref: EHDAA2:0001080 ! median eminence xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: EMAPA:17521 ! median eminence xref: MESH:A06.407.747.734.500 ! median eminence xref: BM:ME ! median eminence is_a: UBERON:0005408 ! circumventricular organ relationship: part_of UBERON:0002198 ! neurohypophysis relationship: only_in_taxon NCBITaxon:8287 {source="ISBN10:0471888893"} ! Sarcopterygii synonym: "eminentia mediana hypothalami" EXACT LATIN [FMA:TA, FMA:74634] xref: AAO:0010539 ! median eminence xref: SCTID:369121004 ! Entire median eminence of neurohypophysis synonym: "eminentia mediana hypothalami" RELATED LATIN [Wikipedia:Median_eminence] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/HypothalamicNuclei.PNG property_value: external_definition "Region of the neurohypophysis.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010539", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0001179", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002198 name: neurohypophysis def: "comprises the posterior lobe of the pituitary gland and is part of the endocrine system[WP]." [Wikipedia:Neurohypophysis] comment: Editor note - request magnocellular cell from CL. Request oxytocin secretion from GO. Notes: "The hypophysis or pituitary gland is derived, in part from an ectodermal outpocketing of the stomodeum (Rathke's Pouch) and in part from the floor of the diencephalon" [http://syllabus.med.unc.edu/courseware/embryo_images/] subset: uberon_slim subset: vertebrate_core synonym: "neurohypophysis" EXACT [] synonym: "pituitary gland, posterior lobe" EXACT [] synonym: "posterior lobe of pituitary" EXACT [] synonym: "posterior pituitary" EXACT [] synonym: "infundibular process" EXACT [FMA:74628] synonym: "neural lobe" EXACT [FMA:74628] synonym: "neural lobe of pituitary gland" EXACT [FMA:74628] synonym: "posterior lobe of pituitary gland" EXACT [FMA:74628] synonym: "neural lobe of pituitary" EXACT [NIF_GrossAnatomy:birnlex_1586] synonym: "posterior pituitary gland" RELATED [BTO:0000937] xref: BTO:0000937 xref: EHDAA:7536 ! neurohypophysis xref: VHOG:0000142 ! neurohypophysis xref: NIF_GrossAnatomy:birnlex_1586 ! Neurohypophysis xref: TAO:0001271 ! neurohypophysis xref: ZFA:0001271 ! neurohypophysis xref: MA:0000178 ! neurohypophysis xref: FMA:74628 ! Neurohypophysis xref: EHDAA2:0001271 ! neurohypophysis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Pituitary_gland_representation.PNG/200px-Pituitary_gland_representation.PNG xref: EMAPA:17519 ! neurohypophysis xref: MESH:A06.407.747.734 ! posterior pituitary gland xref: BM:NY ! neurohypophysis is_a: UBERON:0010134 {source="MA"} ! secretory circumventricular organ relationship: part_of UBERON:0000007 {source="ZFA"} ! pituitary gland relationship: capable_of GO:0008217 ! regulation of blood pressure relationship: capable_of GO:0030103 {source="Wikipedia"} ! vasopressin secretion relationship: capable_of GO:0001992 {source="Wikipedia"} ! regulation of systemic arterial blood pressure by vasopressin relationship: develops_from UBERON:0002346 ! neural ectoderm relationship: develops_from UBERON:0006250 {source="EHDAA2"} ! infundibular recess of 3rd ventricle relationship: only_in_taxon NCBITaxon:7742 {source="PMID:19084529"} ! Vertebrata synonym: "lobus nervosus neurohypophysis" EXACT LATIN [FMA:TA, FMA:74628] synonym: "lobus posterior (glandula pituitaria)" EXACT LATIN [FMA:TA, FMA:74628] synonym: "lobus posterior hypophysis" EXACT LATIN [FMA:TA, FMA:74628] xref: ncithesaurus:Posterior_Lobe_of_the_Pituitary_Gland ! Posterior Lobe of the Pituitary Gland xref: AAO:0010537 ! neurohypophysis xref: SCTID:245527006 ! Entire neurohypophysis property_value: external_definition "The infundibular part of the pituitary gland consisting of two regions.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010537", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0000142", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0032009 [Term] id: UBERON:0003217 name: neural lobe of neurohypophysis def: "The posterior pituitary (or neurohypophysis) comprises the posterior lobe of the pituitary gland and is part of the endocrine system. Despite its name, the posterior pituitary gland is not a gland, per se; rather, it is largely a collection of axonal projections from the hypothalamus that terminate behind the anterior pituitary gland. [WP,unvetted]." [Wikipedia:Neurohypophysis#cite_note-1] comment: TODO - compare with UBERON:0002198 subset: uberon_slim synonym: "pars nervosa of hypophysis" EXACT [] synonym: "pars nervosa of neurohypophysis" EXACT [] synonym: "pars nervosa of posterior lobe of pituitary gland" EXACT [] synonym: "posterior lobe-3" EXACT [] synonym: "posterior lobe of neurohypophysis" EXACT [FMA:74636] synonym: "pars nervosa pituitary gland" EXACT [NIF_GrossAnatomy:birnlex_941] synonym: "pars posterior" EXACT [MA:0000860] synonym: "posterior lobe" BROAD [BTO:0000561] xref: FMA:74636 ! Neural lobe of neurohypophysis xref: NIF_GrossAnatomy:birnlex_941 ! Pars nervosa of hypophysis xref: MA:0000860 ! pars posterior xref: BTO:0000561 ! posterior lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Pituitary_gland_representation.PNG/200px-Pituitary_gland_representation.PNG xref: EHDAA2:0001418 ! pars nervosa xref: VHOG:0001180 ! pars nervosa xref: EHDAA:7542 ! pars nervosa is_a: UBERON:0000481 ! multi-tissue structure disjoint_from: UBERON:0003043 ! posterior part of anterior commissure relationship: part_of UBERON:0002198 ! neurohypophysis synonym: "pars nervosa (neurohypophysis)" EXACT LATIN [FMA:TA, FMA:74636] synonym: "pars nervosa neurohypophysis" EXACT LATIN [FMA:TA, FMA:74636] xref: SCTID:424523008 ! Entire neural lobe of neurohypophysis synonym: "pars nervosa" RELATED [MA:0000860] property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0001180", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003077 ! paraxial mesoderm name: paraxial mesoderm def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]" [Wikipedia:Paraxial_mesoderm, GO:0048339] comment: AO notes: note that all AOs differ in the relationship between this structure and the mesoderm; in ZFA it is a subclass (and this is implied by the GO definition and GO relationships), in AAO it is part of, and in EHDAA2 it develops from the mesoderm (but in EHDAA2 the naming convention is to use 'paraxial mesenchyme', rather than 'paraxial mesoderm'). Also in ZFA it is part of the trunk whereas this conflicts with the division into head and trunk in ehdaa2 (which we follow here) subset: uberon_slim subset: vertebrate_core synonym: "paraxial mesenchyme" EXACT [ZFA:0000255, UBERONREF:0000002] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504 "Developmental Biology"] xref: VHOG:0000114 ! paraxial mesoderm xref: TAO:0000255 ! paraxial mesoderm xref: XAO:0000259 ! paraxial mesoderm xref: ZFA:0000255 ! paraxial mesoderm xref: ncithesaurus:Paraxial_Mesoderm ! Paraxial Mesoderm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png xref: EMAPA:16183 ! paraxial mesenchyme of trunk mesenchyme xref: EMAPA:16751 ! paraxial mesenchyme of mesenchyme of tail of embryo xref: EFO:0003515 ! paraxial mesoderm is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: part_of UBERON:0000926 {source="XAO"} ! mesoderm relationship: develops_from UBERON:0007285 {source="ZFA"} ! presumptive paraxial mesoderm xref: AAO:0010568 ! paraxial mesoderm xref: SCTID:361475002 ! Paraxial mesoderm synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png property_value: external_definition "Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010568", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG]" xsd:string {external_class="VHOG:0000114", ontology="VHOG", source="DOI:10.1002/dvdy.21177 Kusakabe R and Kuratani S. Evolutionary perspectives from development of mesodermal components in the lamprey. Developmental dynamics (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1284009 [Term] id: UBERON:0003102 name: surface structure def: "Organism subdivision that is the collection of anatomical structures on the body surface[ZFA]." [Wikipedia:Surface_structure, ZFA:0000292, VSAO:0000001, http://purl.obolibrary.org/obo/uberon/tracker/24] subset: upper_level synonym: "anatomical surface feature" EXACT [EHDAA2:0003010] synonym: "surface feature" RELATED [] synonym: "surface region" RELATED [] xref: TAO:0000292 ! surface structure xref: XAO:0003028 ! surface structure xref: ZFA:0000292 ! surface structure xref: EHDAA2:0003010 ! anatomical surface feature xref: AEO:0000010 ! anatomical surface feature xref: VSAO:0000001 ! surface structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: overlaps UBERON:0007376 ! outer epithelial layer intersection_of: adjacent_to UBERON:0013514 ! space surrounding organism xref: AAO:0010337 ! surface structure property_value: external_definition "Organism subdivision which is the collection of anatomical structures on the body surface.[ZFA]" xsd:string {ontology="TAO", external_class="TAO:0000292", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: galen:SurfaceRegion ! surface region [Term] id: UBERON:0007376 ! outer epithelial layer name: outer epithelial layer def: "The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. The epidermis of a more complex invertebrate is just one-layer deep, and may be protected by a non-cellular cuticle. The epidermis of a higher vertebrate has many layers, and the outer layers are reinforced with keratin and then die[WP]." [Wikipedia:Epidermis_(zoology)] comment: Editor's note: this grouping class exists primarily to align with GO - see GO:0008544. subset: grouping_class synonym: "hypodermis" RELATED INCONSISTENT [GO:0008544, WBbt:0005733] synonym: "epidermis" NARROW [GO:0008544] synonym: "outer epidermal layer" EXACT [] xref: FBbt:00004993 ! epidermis xref: WBbt:0005733 ! hypodermis xref: HAO:0000298 ! epidermis xref: TADS:0000109 ! adult epidermis is_a: UBERON:0003102 ! surface structure intersection_of: UBERON:0000483 ! epithelium intersection_of: surrounds UBERON:0000468 ! multi-cellular organism relationship: only_in_taxon NCBITaxon:6072 {source="Wikipedia:Epidermis_(zoology)"} ! Eumetazoa [Term] id: UBERON:0002416 name: integumental system def: "organ system that protects the body from damage, comprising the skin and its adnexa (including hair, scales, and nails). The integumentary system has a variety of functions; it may serve to waterproof, cushion and protect the deeper tissues, excrete wastes, regulate temperature and is the location of receptors for pain, sensation, pressure and temperature. In humans the integumentary system additionally provides vitamin D synthesis[WP]." [Wikipedia:Integumentary_system] comment: in FMA, integumentary system = integument + certain glands. Note that here we use integumental system in a general sense, covering a variety of metazoans subset: grouping_class synonym: "integumentary system" EXACT [FMA:72979] synonym: "dermal system" RELATED [MIAA:0000033] xref: EFO:0000807 ! integumental system xref: EHDAA:6520 ! integumental system xref: FMA:72979 ! Integumentary system xref: VHOG:0000403 ! integumental system xref: MA:0000014 ! integumental system xref: MAT:0000033 ! integumental system xref: EMAPA:17524 ! integumental system xref: XAO:0000176 ! dermal system xref: EHDAA2:0000836 ! integumental system xref: MESH:A17 ! integumentary system xref: EV:0100151 ! dermal system xref: HAO:0000421 ! integument xref: FBbt:00004969 ! integumentary system xref: TADS:0000108 ! adult integument xref: MIAA:0000033 ! integumental system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002423 ! hepatobiliary system xref: ncithesaurus:Integumentary_System ! Integumentary System xref: SCTID:361692004 ! Entire integumentary system synonym: "integumentum commune" RELATED LATIN [Wikipedia:Integumentary_system] property_value: homology_notes " (...) the integument of many tetrapods is reinforced by a morphologically and structurally diverse assemblage of skeletal elements. These elements are widely understood to be derivatives of the once all-encompassing dermal skeleton of stem-gnathostomes (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000403", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2008.01043.x Vickaryous MK\, Sire JY\, The integumentary skeleton of tetrapods: origin\, evolution\, and development. J Anat (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0037267 [Term] id: UBERON:0012125 name: dermatological-muscosal system def: "Anatomical system that consists of the integumental system plus all mucosae and submucosae." [http://purl.obolibrary.org/obo/uberon/tracker/53] synonym: "dermatological system" RELATED [OBI:MC] is_a: UBERON:0000467 ! anatomical system relationship: has_part UBERON:0002416 ! integumental system relationship: has_part UBERON:0000009 ! submucosa relationship: has_part UBERON:0000344 ! mucosa [Term] id: UBERON:0000014 name: zone of skin def: "A sub-region of the skin. Note the distinct between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee" [GOC:cjm, Wikipedia:Skin] comment: we assume that mouse, HOG and GAID all mean zone of skin when they say skin. We also choose skin as an exact synonym, as it is more intuitive synonym: "skin" EXACT [MA:0000151] synonym: "portion of skin" EXACT [] synonym: "skin zone" EXACT [] synonym: "skin region" EXACT [] synonym: "region of skin" EXACT [] xref: FMA:86166 ! Zone of skin xref: EHDAA:6530 ! skin xref: MA:0000151 ! skin xref: GAID:933 ! skin xref: VHOG:0000860 ! skin xref: MAT:0000284 ! skin xref: MIAA:0000284 ! skin xref: OpenCyc:Mx4rvVjX3ZwpEbGdrcN5Y29ycA ! skin xref: EHDAA2:0001844 ! skin (also: UBERON:0002097 'skin of body') (also: UBERON:0002199 'integument') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Skin.svg/200px-Skin.svg.png xref: MESH:A17.815 ! skin (also: UBERON:0002097 'skin of body') (also: UBERON:0002199 'integument') xref: EV:0100152 ! skin is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002097 ! skin of body xref: SCTID:20795001 ! Structure of skin region xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/HumanSkinDiagram.jpg property_value: homology_notes " (...) it is well-established that neural crest cells contribute to both the dermal skeleton (craniofacial bone, teeth, and the caudal fin rays of teleosts) and the integument, including craniofacial dermis and all pigment cells outside the retina (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000860", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2008.01043.x Vickaryous MK\, Sire JY\, The integumentary skeleton of tetrapods: origin\, evolution\, and development. J Anat (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002097 name: skin of body def: "Nonparenchymatous organ that consists of the dermis and epidermis. Subdivisions of the skin surround various body parts; as a whole, the skin constitutes the external layer of the body. Examples: There is only one skin[FMA]. Surface structure that consists of the external membranous integument of the animal." [OMD:skin, Wikipedia:Skin, FMA:7163] comment: Note that FMA uses 'skin' for the entire organ. XAO seems consistent. MA seems to use it analagously to zone of skin subset: uberon_slim subset: major_organ synonym: "entire skin" EXACT [] synonym: "skin" RELATED [] synonym: "pelt" RELATED [] synonym: "integument" RELATED [] xref: galen:Skin ! skin xref: BTO:0001253 xref: FMA:7163 ! Skin xref: OpenCyc:Mx4rvVjX3ZwpEbGdrcN5Y29ycA xref: XAO:0000023 ! skin xref: ncithesaurus:Skin ! Skin xref: EFO:0000962 ! skin xref: EHDAA2:0001844 ! skin (also: UBERON:0000014 'zone of skin') (also: UBERON:0002199 'integument') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Skin.svg/200px-Skin.svg.png xref: MESH:A17.815 ! skin (also: UBERON:0000014 'zone of skin') (also: UBERON:0002199 'integument') xref: EMAPA:17525 ! skin of integumental system is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0002199 ! integument relationship: has_part UBERON:0001003 ! epidermis relationship: has_part UBERON:0002067 ! dermis relationship: has_part UBERON:0000014 ! zone of skin relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer xref: SCTID:181469002 ! Entire skin xref: UMLS:C1123023 [Term] id: UBERON:0001003 name: epidermis def: "The outer layer of the skin[WP]. cellular, multilayered epithelium derived from the ectoderm[ZFA]." [Wikipedia:Epidermis_(skin), ISBN10:0073040584 "Vertebrates\, Kardong"] comment: Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. In terrestrial vertebrates the epidermis often forms an outer keratinized or cornified layer, the stratum corneum. Interaction between the epideris and dermis gives rise to feathers (birds), hair and mammary glands (mammals), teeth and scales (placoid: chondrichthyans; cosmoids, ganoid, cycloid in bony fishes). subset: uberon_slim subset: vertebrate_core synonym: "adult epidermis" EXACT [] synonym: "vertebrate epidermis" EXACT [] synonym: "skin" BROAD [] xref: AAO:0000143 ! epidermis xref: BTO:0000404 ! epidermis xref: FMA:70596 ! Epidermis xref: GAID:932 ! epidermis xref: VHOG:0000077 ! epidermis xref: MA:0000153 ! epidermis xref: MAT:0000154 ! epidermis xref: MIAA:0000154 ! epidermis xref: TAO:0000105 ! epidermis xref: XAO:0000028 ! epidermis xref: ZFA:0000105 ! epidermis xref: ncithesaurus:Epidermis ! Epidermis xref: EFO:0000954 ! epidermis xref: MESH:A10.272.497 ! epidermis xref: EV:0100153 ! epidermis is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0002199 ! integument relationship: developmentally_replaces UBERON:0003055 ! periderm relationship: develops_from UBERON:0007383 ! enveloping layer of ectoderm relationship: surrounds UBERON:0000468 ! multi-cellular organism relationship: part_of UBERON:0002097 ! skin of body relationship: adjacent_to UBERON:0002067 ! dermis xref: SCTID:361694003 ! Entire epidermis property_value: external_definition "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000143", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass external integument structures (AAO:0000961)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000143", date_retrieved="2012-06-20"} property_value: external_definition "A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000105", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) outer epithelia in all metazoan animals are homologous. (...) The ancestor of all metazoans likely had an epidermis with a basal extracellular matrix (ECM), an apical extracellular glycocalyx, and one cilium with a striated rootlet per cell.[well established][VHOG]" xsd:string {external_class="VHOG:0000077", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.71-72", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "epidermal" xsd:string xref: UMLS:C0014520 [Term] id: UBERON:0010083 name: future dermis comment: Editor notes: check development intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_into UBERON:0002067 ! dermis relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument relationship: develops_from UBERON:0004016 {source="XAO"} ! dermatome relationship: develops_from UBERON:0003089 {source="EHDAA2"} ! sclerotome xref: EHDAA2:0000598 ! future dermis def: "Mesenchyme that develops_into a dermis." [OBOL:automatic] [Term] id: UBERON:0002067 name: dermis def: "The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]." [Wikipedia:Dermis, ZFIN:curator] comment: Editor notes: Consider adding a layer-of-skin grouping class for all skin layers subset: uberon_slim subset: vertebrate_core synonym: "corium" RELATED [BTO:0000294] synonym: "cutis" RELATED [BTO:0000294] synonym: "vertebrate dermis" EXACT [] xref: AAO:0000128 ! dermis xref: BTO:0000294 xref: FMA:70323 ! Dermis xref: GAID:1321 ! dermis xref: VHOG:0000108 ! dermis xref: MA:0000152 ! dermis xref: MAT:0000153 ! dermis xref: MIAA:0000153 ! dermis xref: TAO:0001119 ! dermis xref: XAO:0000217 ! dermis xref: ZFA:0001119 ! dermis xref: ncithesaurus:Dermis ! Dermis xref: EFO:0000953 ! dermis xref: MESH:A17.815.180 ! dermis xref: EV:0100154 ! dermis is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0002097 {source="FMA"} ! skin of body relationship: part_of UBERON:0002199 ! integument relationship: adjacent_to UBERON:0001003 ! epidermis relationship: adjacent_to UBERON:0002072 ! hypodermis relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest xref: SCTID:361696001 ! Entire dermis relationship: immediate_transformation_of UBERON:0010083 {evidence="definitional"} ! future dermis synonym: "corium" RELATED LATIN [Wikipedia:Dermis] xref: http://upload.wikimedia.org/wikipedia/commons/2/23/EpidermisPainted.svg property_value: external_definition "A collagenous layer of the skin subjacent to the epidermis and covering the hypodermis. It contains various types of cells (e.g. fibroblasts, pigment cells, nerve, blood vessels and scales. Le Guellec et al, 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001119", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "When approaching controversies surrounding skin evolution, we need to remember that the skin consists of two layers, an epidermis and a dermis, not a single evolving structure. (...) It is little wonder that controversies about homology exist. If we think of the epidermis, the dermis, and their interactions as an evolving unit, then their specialized products (hair, feathers, and reptilian scales) are broadly homologous.[well established][VHOG]" xsd:string {external_class="VHOG:0000108", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.231-232 see also p.209 and p.228 and Figure 6-1", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "dermal" xsd:string xref: UMLS:C0011646 [Term] id: UBERON:0002072 name: hypodermis def: "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA]." [Wikipedia:Hypodermis] comment: AO Notes: BTO has 'subcutis', as part of dermis. We follow FMA in having distinct classes for hypoderis and superficial fascia, and including these as part of the non-skin intgeument. subset: uberon_slim subset: vertebrate_core synonym: "vertebrate hypodermis" EXACT [] synonym: "hypoderm" EXACT [] synonym: "subcutaneous tissue" RELATED [Wikipedia:Hypodermis] synonym: "subcutis" RELATED [] synonym: "superficial fascia" RELATED INCONSISTENT [] synonym: "sub-tegumental tissue" RELATED [BTO:0004525] synonym: "subtegumental tissue" RELATED [BTO:0004525] synonym: "tela subcutanea" RELATED LATIN [Wikipedia:Hypodermis] xref: FMA:70544 ! Hypodermis xref: TAO:0001136 ! hypodermis xref: ZFA:0001136 ! hypodermis xref: BTO:0001314 ! subcutis xref: ncithesaurus:Subcutis ! subcutis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6d/Skin.svg/200px-Skin.svg.png is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0002199 {source="ZFA"} ! integument relationship: develops_from UBERON:0000926 ! mesoderm relationship: adjacent_to UBERON:0002067 ! dermis property_value: external_definition "A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001136", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "hypodermal" xsd:string xref: UMLS:C0278403 [Term] id: UBERON:0011818 name: superficial fascia def: "Superficial fascia is found in the subcutis in most regions of the body, blending with the reticular layer of the dermis. It is present on the face, over the upper portion of the sternocleidomastoid, at the nape of the neck, and overlying the sternum. It is comprised mainly of loose areolar connective tissue and adipose and is the layer that primarily determines the shape of a body. In addition to its subcutaneous presence, this type of fascia surrounds organs and glands, neurovascular bundles, and is found at many other locations where it fills otherwise unoccupied space. It serves as a storage medium of fat and water; as a passageway for lymph, nerve and blood vessels; and as a protective padding to cushion and insulate. Superficial fascia is present, but does not contain fat, in the eyelids, ear, scrotum, penis and clitoris." [Wikipedia:Superficial_fascia] comment: We follow FMA, BTO, NCIT and WP in making this a distinct class from hypodermis. synonym: "subcutaneous tissue" EXACT [FMA:9630] synonym: "tela subcutanea" EXACT LATIN [FMA:TA] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0002199 {source="FMA"} ! integument xref: FMA:9630 ! superficial fascia xref: ncithesaurus:Superficial_Fascia ! Superficial Fascia xref: MESH:A10.165.887 ! subcutaneous tissue xref: BTO:0004525 ! subcutaneous tissue xref: GAID:929 ! subcutaneous tissue xref: SCTID:361713003 ! Entire subcutaneous tissue [Term] id: UBERON:0002199 name: integument def: "The dermis, epidermis and hypodermis." [Wikipedia:Integument] comment: Usage notes: in FMA intergument = skin+superficial fascia(hypodermis), skin=dermis+epidermis+hair_nail. Note that the definition provided here excludes the more general sense of the term 'integument' used in invertebrates. Note that the VSAO class appears to include adnexa by its definition. subset: uberon_slim subset: vertebrate_core synonym: "skin" RELATED [] synonym: "the integument" EXACT [FMA:74657] synonym: "dermal system" RELATED [BTO:0000634] synonym: "dermoid system" RELATED [BTO:0000634] synonym: "Hautsystem" RELATED [BTO:0000634] synonym: "tegument" RELATED [BTO:0000634] xref: AAO:0000239 ! integument xref: BTO:0000634 ! integument xref: FMA:74657 ! Integument xref: galen:Integument xref: TAO:0000368 ! integument xref: ZFA:0000368 ! integument xref: EHDAA2:0001844 ! skin (also: UBERON:0000014 'zone of skin') (also: UBERON:0002097 'skin of body') xref: MESH:A17.815 ! skin (also: UBERON:0000014 'zone of skin') (also: UBERON:0002097 'skin of body') xref: VSAO:0000029 ! integument is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0002416 ! integumental system relationship: surrounds UBERON:0000468 ! multi-cellular organism relationship: has_part UBERON:0002072 ! hypodermis relationship: has_part UBERON:0002097 ! skin of body relationship: only_in_taxon NCBITaxon:7711 ! Chordata synonym: "integumentum commune" EXACT LATIN [FMA:TA, FMA:74657] property_value: external_definition "Anatomical system that protects the body from damage, comprising the skin and its appendages.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000239", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "The outer protective barrier that separates the animal from its aquatic environment. Le Guellec et al, 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000368", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Surface structure that is the outer protective covering of the body.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000029", date_retrieved="2012-08-14", source="PSPUB:0000170"} property_value: has_relational_adjective "integumental" xsd:string property_value: has_relational_adjective "integumentary" xsd:string [Term] id: UBERON:0002200 name: vasculature of head def: "Vasculature that is part of a head [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "cranial vasculature" EXACT [] synonym: "head vasculature" RELATED [] synonym: "adult head vascular network" EXACT [OBOL:automatic] synonym: "adult head vasculature" EXACT [OBOL:automatic] synonym: "head vascular network" EXACT [OBOL:automatic] synonym: "vascular network of adult head" EXACT [OBOL:automatic] synonym: "vascular network of head" EXACT [OBOL:automatic] synonym: "vasculature of adult head" EXACT [OBOL:automatic] xref: FMA:74710 ! Vasculature of head xref: TAO:0001267 ! cranial vasculature xref: ZFA:0001267 ! cranial vasculature xref: EFO:0003656 ! cranial vasculature is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000033 ! head xref: XAO:0004152 ! head vasculature [Term] id: UBERON:0011362 name: cranial blood vasculature synonym: "set of blood vessels of head" EXACT [] xref: TAO:0005297 ! cranial blood vessel intersection_of: UBERON:0004537 ! blood vasculature intersection_of: part_of UBERON:0000033 ! head xref: ZFA:0005297 ! cranial blood vessel property_value: external_definition "Blood vessel part of cranial vasculature.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005297", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "cranial blood vessels" RELATED PLURAL [TAO:0005297] def: "A blood vasculature that is part of a head." [OBOL:automatic] [Term] id: UBERON:0011363 name: cranial lymph vasculature intersection_of: UBERON:0004536 ! lymph vasculature intersection_of: part_of UBERON:0000033 ! head synonym: "set of lymphatic vessels of head" EXACT [FMA:224562] xref: TAO:0005298 ! cranial lymph vessel xref: ZFA:0005298 ! cranial lymph vessel xref: FMA:224562 ! set of lymphatic vessels of head synonym: "cranial lymph vessels" RELATED PLURAL [TAO:0005298] def: "A lymph vasculature that is part of a head." [OBOL:automatic] [Term] id: UBERON:0002201 name: vasculature of trunk def: "A vasculature that is part of a trunk [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "trunk vasculature" EXACT [] synonym: "torso vascular network" EXACT [OBOL:automatic] synonym: "torso vasculature" EXACT [OBOL:automatic] synonym: "trunk vascular network" EXACT [OBOL:automatic] synonym: "vascular network of torso" EXACT [OBOL:automatic] synonym: "vascular network of trunk" EXACT [OBOL:automatic] synonym: "vasculature of torso" EXACT [OBOL:automatic] xref: FMA:74712 ! Vasculature of trunk xref: TAO:0005024 ! trunk vasculature xref: ZFA:0005024 ! trunk vasculature is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0002202 name: submucosa of trachea comment: This class was created automatically from a combination of ontologies synonym: "trachea submucosa" EXACT [] synonym: "tracheal submucosa" EXACT [] synonym: "submucosa of windpipe" EXACT [OBOL:automatic] synonym: "windpipe submucosa" EXACT [OBOL:automatic] xref: FMA:7472 ! Submucosa of trachea xref: MA:0001860 ! trachea submucosa xref: ncithesaurus:Trachea_Submucosa ! Trachea Submucosa xref: BTO:0002115 ! tela submucosa tracheae is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0003126 ! trachea xref: SCTID:4419000 ! Tracheal submucosa def: "A submucosa that is part of a trachea." [OBOL:automatic] xref: UMLS:C0225586 [Term] id: UBERON:0002203 name: vasculature of eye def: "Vasculature that is part of the eye region." [OBOL:automatic, https://sourceforge.net/tracker/?func=detail&aid=3489658&group_id=76834&atid=994726] comment: not part of the eye in ZFA. Note this changed to a blood vessel in ZFA subset: vertebrate_core synonym: "eye vasculature" RELATED [] synonym: "ocular vasculature" EXACT [] synonym: "optic vasculature" RELATED [] synonym: "eye vascular network" EXACT [OBOL:automatic] synonym: "vascular network of eye" EXACT [OBOL:automatic] synonym: "ocular blood vessel" EXACT [ZFA:0007057] xref: FMA:74743 ! Vasculature of eye xref: ZFA:0007057 ! ocular vasculature is_a: UBERON:0002200 ! vasculature of head intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0000019 {source="FMA"} ! camera-type eye xref: SCTID:123846009 ! Structure of ocular blood vessel xref: TAO:0007057 ! ocular blood vessel [Term] id: UBERON:0003071 name: eye primordium alt_id: UBERON:0005060 def: "Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles." [ZFA:0000570, GO:0046619] comment: AO notes: TODO - check that GO's optic placode is the same as ZFA's eye primordium; we may want to have separate term for ocular primordium precursor. XAO has both optic field and eye primordium synonym: "eye anlage" RELATED [XAO:0000227] synonym: "eye field" RELATED [] synonym: "optic field" RELATED [] synonym: "optic primordium" EXACT [] synonym: "ocular primordium" EXACT [] synonym: "occular primordium" EXACT [] synonym: "optic placode" EXACT [GO:0046619] synonym: "optic placode of camera-type eye" EXACT [GO:0046619, UBERON:cjm] synonym: "eye placode" EXACT [OBOL:automatic] xref: TAO:0000570 ! optic primordium xref: XAO:0000227 ! eye primordium xref: XAO:0004090 ! optic field xref: ZFA:0000570 ! optic primordium xref: EFO:0003541 ! optic primordium is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium intersection_of: UBERON:0001048 ! primordium intersection_of: develops_into UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0003056 {source="XAO", source="PMID:16496288"} ! pre-chordal neural plate relationship: develops_from UBERON:0003056 ! pre-chordal neural plate xref: AAO:0011038 ! eye primordium xref: EHDAA2:0004431 ! optic primordium [Term] id: UBERON:0005426 ! lens vesicle name: lens vesicle def: "Portion of tissue that gives rise to the lens." [ZFIN:curator, https://sourceforge.net/tracker/?func=detail&atid=994726&aid=3514998&group_id=76834] comment: Development notes: the lens of zebrafish (and other teleosts) forms from delamination of cells from the lens placode; thus, there is no formation of a hollow lens vesicle, in contrast to the situation in mammals and birds (Glass and Dahm, 2004) [PMID:16496288] The lens of the zebrafish forms by delamination of lens placodal cells and not through invagination. This results in a solid spherical mass as opposed to a hollow lens vesicle. Detachment of the solid lens vesicle of zebrafish at 24b26 hpf is accomplished in part by apoptosis, similar to mammals[ZFA] synonym: "solid lens vesicle" NARROW SENSU [ZFA:0001679] synonym: "hollow lens vesicle" NARROW SENSU [] subset: vertebrate_core xref: ZFA:0001679 ! solid lens vesicle xref: VHOG:0001163 ! lens vesicle xref: EMAPA:17163 ! lens vesicle xref: EHDAA:4737 ! lens vesicle xref: EHDAA2:0000983 ! lens vesicle is_a: UBERON:0000479 ! portion of tissue relationship: develops_from UBERON:0003073 ! lens placode relationship: has_quality PATO:0001736 {gci_relation="part_of", gci_filler="NCBITaxon:32443", notes="teleosts"} ! solid configuration relationship: has_quality PATO:0002078 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="Mammals"} ! hollow xref: SCTID:361510002 ! Lens vesicle xref: TAO:0002205 ! lens vesicle property_value: external_definition "A vesicle formed from the lens pit of the embryo, developing into the crystalline lens. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001163", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/lens+vesicle", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {external_class="VHOG:0001163", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004128 name: optic vesicle def: "The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]." [GO:0003404, Wikipedia:Optic_vesicles] comment: Genes: Six3, Pax6, Rx1 are expressed together in the tip of the neural plate [ISBN:9780878932504 "Developmental Biology"]. Development notes: During subsequent develop- ment, the optic vesicle invaginates and becomes a two-layered structure with an inner neural retina and outer retinal pigment epithelium. As soon as the developing optic vesicle makes contact with the overlying ectoderm, it induces the ectoderm to thicken and form the lens placode PMID:16496288 subset: vertebrate_core synonym: "evagination" RELATED [] xref: XAO:0000228 ! eye vesicle xref: ZFA:0000050 ! optic vesicle xref: EMAPA:16540 ! optic vesicle xref: VHOG:0000165 ! optic vesicle xref: EHDAA2:0001320 ! optic vesicle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Gray863.png/200px-Gray863.png is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye relationship: develops_from UBERON:0003071 {source="ZFA"} ! eye primordium relationship: induced_by UBERON:0004880 ! chordamesoderm xref: ncithesaurus:Optic_Vesicle ! Optic Vesicle xref: AAO:0011039 ! optic vesicle xref: SCTID:362864008 ! Entire optic vesicle xref: TAO:0000050 ! optic vesicle synonym: "ocular vesicle" RELATED [VHOG:0000165] property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles.[well established][VHOG]" xsd:string {external_class="VHOG:0000165", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231106 [Term] id: UBERON:0003072 name: optic cup def: "Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]." [ZFA:0001202, MP:0004269, Optic_cup_(embryology)] subset: vertebrate_core synonym: "eye cup" RELATED [] xref: ZFA:0001202 ! optic cup xref: ncithesaurus:Optic_Cup ! Optic Cup xref: VHOG:0000167 ! optic cup xref: EHDAA2:0001303 ! optic cup xref: EMAPA:16674 ! optic cup xref: EHDAA:2912 ! optic cup is_a: UBERON:0000481 ! multi-tissue structure relationship: develops_from UBERON:0004128 {source="ZFA"} ! optic vesicle relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye relationship: induced_by UBERON:0003073 ! lens placode xref: SCTID:308789007 ! Entire optic cup xref: TAO:0001202 ! optic cup synonym: "ocular cup" RELATED [VHOG:0000167] property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup.[well established][VHOG]" xsd:string {external_class="VHOG:0000167", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231109 [Term] id: UBERON:0005424 ! presumptive retinal pigmented epithelium name: presumptive retinal pigmented epithelium def: "Portion of tissue that is the outer layer of the optic cup and will become the retinal pigmented epithelium." [ZFIN:curator] subset: vertebrate_core synonym: "outer layer optic cup" EXACT [ZFA:0000064] synonym: "optic cup outer layer" EXACT [EHDAA2:0001306] synonym: "presumptive pigmented epithelia" EXACT PLURAL [ZFA:0000064] xref: TAO:0000064 ! presumptive pigmented epithelium xref: ZFA:0000064 ! presumptive retinal pigmented epithelium xref: EHDAA2:0001306 ! optic cup outer layer xref: VHOG:0000492 ! optic cup outer layer xref: EMAPA:16677 ! outer layer of optic cup is_a: UBERON:0006598 ! presumptive structure relationship: part_of UBERON:0003072 ! optic cup synonym: "presumptive pigmented epithelium" RELATED [TAO:0000064] property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0000492", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005425 ! presumptive neural retina name: presumptive neural retina def: "Portion of tissue that is the inner layer of the optic cup and will become the neural retina." [ZFIN:curator] subset: vertebrate_core synonym: "inner layer optic cup" EXACT [ZFA:0001071] synonym: "presumptive retinas" EXACT PLURAL [ZFA:0001071] synonym: "optic cup inner layer" EXACT [EHDAA2:0001304] xref: EHDAA2:0001304 ! optic cup inner layer xref: VHOG:0000490 ! optic cup inner layer xref: TAO:0001071 ! presumptive retina xref: ZFA:0001071 ! presumptive neural retina xref: EMAPA:16675 ! inner layer is_a: UBERON:0006598 ! presumptive structure relationship: part_of UBERON:0003072 ! optic cup synonym: "presumptive retina" RELATED [TAO:0001071] property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0000490", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002205 name: manubrium of sternum def: "broad, upper part of the sternum. Located ventrally with a quadrangular shape, wider superiorly and narrower inferiorly, it articulates with the clavicles and the first two ribs[WP]." [Wikipedia:Manubrium] comment: May be cartilage in some species. subset: uberon_slim synonym: "manubrium" BROAD [] synonym: "manubrium of sternum" EXACT [] synonym: "sternal manubrium" EXACT [MA:0001332] synonym: "manubrium sterni" EXACT [EMAPA:18723] xref: FMA:7486 ! Manubrium xref: GAID:247 ! manubrium xref: OpenCyc:Mx4rvXOLAZwpEbGdrcN5Y29ycA xref: EMAPA:18723 ! manubrium sterni xref: MA:0001332 ! sternal manubrium xref: OpenCyc:Mx4rvXOLAZwpEbGdrcN5Y29ycA ! manubrium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/23/Gray116.png/200px-Gray116.png xref: MESH:A02.835.232.904.766.442 ! manubrium is_a: UBERON:0010363 {source="Kardong"} ! endochondral element disjoint_from: UBERON:0006722 ! manubrium of malleus relationship: part_of UBERON:0000975 ! sternum relationship: develops_from UBERON:0011301 ! manubrium sternum pre-cartilage condensation relationship: serially_homologous_to UBERON:0002208 {source="Kardong"} ! sternebra xref: ncithesaurus:Sternal_Manubrium ! Sternal Manubrium xref: SCTID:182014008 ! Entire manubrium sterni xref: http://upload.wikimedia.org/wikipedia/commons/2/23/Gray116.png xref: UMLS:C1710195 [Term] id: UBERON:0011301 ! manubrium sternum pre-cartilage condensation name: manubrium sternum pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme relationship: part_of UBERON:0000975 {source="EHDAA2"} ! sternum synonym: "manubrium sterni pre-cartilage condensation" EXACT [EHDAA2:0001063] xref: EHDAA2:0001063 ! manubrium sterni pre-cartilage condensation xref: EHDAA:9563 ! manubrium sterni pre-cartilage condensation [Term] id: UBERON:0002207 ! xiphoid process name: xiphoid process def: "A cartilaginous extension to the distal part of the sternum." [Wikipedia:Xiphoid_process, https://sourceforge.net/tracker/?func=detail&aid=3153001&group_id=76834&atid=1205376] comment: this class may represent a mixed bony-cartilage element, or it may be the superclass of either purely cartilage or purely ossified elements. Taxon notes: usually ossified in the adult human. By age 15 to 29, the xiphoid usually fuses to the body of the sternum with a fibrous joint. Unlike the synovial articulation of major joints, this is non-movable. Much the way the first seven ribs articulate with the sternum, the cartilage in the celiac plexus joins on the xiphoid process, reinforcing it, and indirectly attaches the costal cartilage to the sternum. [WP,unvetted] subset: uberon_slim synonym: "xiphoid process of sternum" EXACT [] synonym: "xiphoid process" EXACT [FMA:7488] synonym: "processus xiphoideus" RELATED [Wikipedia:Xiphoid_process] synonym: "xiphisternum" EXACT [Wikipedia:Xiphoid_process] synonym: "xiphoid" RELATED [Wikipedia:Xiphoid_process] synonym: "xiphoid process" RELATED [Wikipedia:Xiphoid_process] synonym: "xiphoideus" RELATED [Wikipedia:Xiphoid_process] synonym: "xiphosternal junction" RELATED [Wikipedia:Xiphoid_process] synonym: "xyphoid" RELATED [Wikipedia:Xiphoid_process] synonym: "metasternum" RELATED [Wikipedia:Xiphoid_process] xref: FMA:7488 ! Xiphoid process xref: MA:0001334 ! xiphisternum xref: ncithesaurus:Xiphoid_Process ! Xiphoid Process xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray117.png/200px-Gray117.png is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0000975 ! sternum relationship: serially_homologous_to UBERON:0002208 {source="Kardong"} ! sternebra xref: SCTID:272711000 ! Entire xiphoid process of sternum synonym: "processus xiphoideus" RELATED LATIN [Wikipedia:Xiphoid_process] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray117.png xref: UMLS:C0043356 [Term] id: UBERON:0006431 name: xiphoid process bone synonym: "bone tissue of xiphoid process" EXACT [FMA:32577] synonym: "xiphoid bone" RELATED [Wikipedia:Xiphoid_process] xref: GAID:248 ! xiphoid bone xref: FMA:32577 ! bone tissue of xiphoid process intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0002207 ! xiphoid process def: "A bone tissue that is part of a xiphoid process." [OBOL:automatic] [Term] id: UBERON:0006430 name: xiphoid cartilage subset: uberon_slim synonym: "xiphoid cartilage" EXACT [] synonym: "ensiform cartilage" RELATED [Wikipedia:Xiphoid_process] synonym: "cartilage of xiphoid process" EXACT [FMA:32574] synonym: "xiphoid process cartilage" EXACT [FMA:32574] xref: FMA:32574 ! cartilage of xiphoid process xref: MA:0001884 ! xiphoid cartilage xref: EMAPA:18725 ! xiphisternum xref: AAO:0000940 ! xiphisternum is_a: UBERON:0000398 ! sternal cartilage intersection_of: UBERON:0002236 ! costal cartilage intersection_of: part_of UBERON:0002207 ! xiphoid process property_value: external_definition "Distal, cartilaginous portion of the sternum.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000940", date_retrieved="2012-06-20", source="AAO:LAP"} def: "A costal cartilage that is part of a xiphoid process." [OBOL:automatic] [Term] id: UBERON:0011124 name: xiphisternal joint def: "The xiphisternal joint (or xiphisternal synchondrosis) is a location near the bottom of the sternum, where the body of the sternum and the xiphoid process." [Wikipedia:Xiphisternal_joint] synonym: "xiphisternal junction" RELATED [Wikipedia:Xiphisternal_joint] synonym: "xiphisternal synchdrondosis" RELATED [Wikipedia:Xiphisternal_joint] synonym: "synchondrosis xiphisternalis" EXACT [FMA:7503] is_a: UBERON:0002216 {source="FMA"} ! symphysis intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0006820 ! body of sternum intersection_of: connects UBERON:0002207 ! xiphoid process xref: FMA:7503 ! xiphisternal joint xref: SCTID:118923007 ! Xiphisternal symphysis xref: SCTID:118924001 ! Xiphisternal synostosis xref: http://upload.wikimedia.org/wikipedia/commons/2/23/Gray116.png [Term] id: UBERON:0002208 name: sternebra def: "one of the bony segments of the sternum[TFD]." [Wikipedia:Sternebra, http://medical-dictionary.thefreedictionary.com/sternebra] comment: Note that some definitions state that this a segment of the primordial sternum. subset: uberon_slim xref: FMA:7489 ! Sternebra xref: MA:0001333 ! sternebra xref: EMAPA:18724 ! sternebral bone synonym: "sternebral bone" RELATED [EMAPA:18724] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/12/Illu_thoracic_cage.jpg/200px-Illu_thoracic_cage.jpg is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0000975 {source="MA"} ! sternum relationship: develops_from UBERON:0006295 ! sternebral bone pre-cartilage condensation xref: SCTID:95955004 ! Entire sternebra [Term] id: UBERON:0002209 name: fibrous joint def: "Nonsynovial joint in which the articulating bones or cartilages are connected by ligaments. Examples: sagittal suture, inferior tibiofibular syndesmosis, gomphosis.[FMA]" [Wikipedia:Fibrous_joint, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "articulatio fibrosa" EXACT [] xref: FMA:7492 ! Fibrous joint xref: MA:0000321 ! fibrous joint xref: ZFA:0005156 ! fibrous joint xref: EHDAA2:0003178 ! fibrous joint xref: AEO:0000178 ! fibrous joint is_a: UBERON:0011134 {source="FMA"} ! nonsynovial joint relationship: has_part CL:0002320 {source="AEO"} ! connective tissue cell xref: SCTID:37772004 ! Entire fibrous joint xref: TAO:0005156 ! fibrous joint synonym: "junctura fibrosa" RELATED LATIN [Wikipedia:Fibrous_joint] property_value: external_definition "A joint where fibrous tissue such as ligament connects two calcified tissues.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005156", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0011206 name: hinge joint def: "A joint that allows motion around an axis." [BTO:0004707, Wikipedia:Hinge_joint] synonym: "ginglymus" RELATED [BTO:0004707] is_a: UBERON:0000982 {source="BTO"} ! skeletal joint xref: BTO:0004707 ! hinge joint xref: http://upload.wikimedia.org/wikipedia/commons/4/4b/Gelenke_Zeichnung01.jpg xref: SCTID:335391000 ! Entire ginglymus xref: galen:HingeJoint ! hinge joint [Term] id: UBERON:0002210 name: syndesmosis def: "Fibrous joint in which the articulating bones or cartilages of the vertebral column and the limbs as well as articulating ossicles, are connected by skeletal ligaments or membranes. Examples: Intervertebral syndesmosis, inferior tibiofibular joint.[FMA]" [Wikipedia:Syndesmosis, FMA:FMA] subset: uberon_slim xref: FMA:7494 ! Syndesmosis xref: MA:0001500 ! syndesmosis is_a: UBERON:0002209 ! fibrous joint is_a: UBERON:0002213 ! cartilaginous joint xref: SCTID:89358004 ! Entire syndesmosis [Term] id: UBERON:0001485 name: knee joint def: "The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation. Since in humans the knee supports nearly the whole weight of the body, it is the joint most vulnerable both to acute injury and the development of osteoarthritis. [WP,unvetted]." [Wikipedia:Knee] subset: uberon_slim synonym: "joint of knee" EXACT [OBOL:automatic] synonym: "articulatio genus" RELATED LATIN [Wikipedia:Knee] xref: FMA:35175 ! Knee joint xref: GAID:114 ! knee joint xref: galen:KneeJoint xref: VHOG:0001003 ! knee joint xref: MA:0000471 ! knee joint xref: ncithesaurus:Knee_Joint ! Knee Joint xref: EFO:0001957 ! knee joint (also: UBERON:0001465 'knee') xref: OpenCyc:Mx4rwCuaYZwpEbGdrcN5Y29ycA ! knee joint xref: EMAPA:19137 ! knee joint xref: MESH:A02.835.583.475 ! knee joint is_a: UBERON:0002217 ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000981 ! femur intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0002446 ! patella relationship: part_of UBERON:0001465 ! knee xref: SCTID:182204005 ! Entire knee joint relationship: develops_from UBERON:0006256 {evidence="definitional"} ! knee joint primordium xref: http://upload.wikimedia.org/wikipedia/commons/c/ca/Knee.agr.jpg xref: UMLS:C0022745 [Term] id: UBERON:0011166 name: patellofemoral joint synonym: "femorapatellar joint" EXACT [] synonym: "femoropatellar joint" EXACT [] synonym: "patello femoral joint" EXACT [galen:PatelloFemoralJoint] is_a: UBERON:0011139 {source="FMA"} ! synovial limb joint relationship: part_of UBERON:0001485 ! knee joint relationship: connects UBERON:0000981 ! femur relationship: connects UBERON:0002446 ! patella xref: FMA:43574 ! patellofemoral joint xref: SCTID:182202009 ! Entire patellofemoral joint xref: galen:PatelloFemoralJoint ! patello femoral joint [Term] id: UBERON:0009005 name: femorotibial joint def: "One of the two primary bendings of a typical leg, pertains to the femur and the tibia." [BTO:0004396] comment: Editor notes: proposed OWL definition: skeletal join that connects ONLY tibia and femur synonym: "femoratibial joint" EXACT [] synonym: "tibiofemoral joint" EXACT [FMA:43571] synonym: "knee" RELATED [] is_a: UBERON:0011139 {source="FMA"} ! synovial limb joint relationship: part_of UBERON:0001485 ! knee joint relationship: connects UBERON:0000979 ! tibia relationship: connects UBERON:0000981 ! femur xref: SCTID:182203004 ! Entire femorotibial joint xref: BTO:0004396 ! femorotibial joint xref: FMA:43571 ! tibiofemoral joint [Term] id: UBERON:0011123 name: stifle joint def: "a complex joint in the hind limbs of quadruped mammals such as the sheep, horse or dog. It is the equivalent joint to the human knee. It is often the largest synovial joint in the body." [Wikipedia:Stifle_joint] synonym: "femoropatellar joint" RELATED [] is_a: UBERON:0000982 ! skeletal joint relationship: connects UBERON:0000981 ! femur relationship: connects UBERON:0000979 ! tibia relationship: connects UBERON:0002446 ! patella relationship: part_of UBERON:0000978 ! leg xref: SCTID:116010006 ! Stifle joint xref: ncithesaurus:Stifle_Joint ! stifle joint xref: MESH:A13.473.683 [Term] id: UBERON:0011088 name: ligament of knee joint synonym: "knee joint ligament" EXACT [FMA:44580] is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001485 ! knee joint xref: FMA:44580 ! ligament of knee joint xref: SCTID:182440009 ! Entire ligament of knee joint def: "A ligament that is part of a knee joint." [OBOL:automatic] [Term] id: UBERON:0003676 name: patellar ligament def: "The central portion of the common tendon of the quadriceps femoris. It is attached to the apex of the PATELLA and to the lower part of the tubercle of the TIBIA." [MESH:A02.513.514.475, Wikipedia:Patellar_ligament] synonym: "central band of tendon of quadriceps femoris" EXACT [FMA:44581] synonym: "ligamentum patella" EXACT [FMA:44581] synonym: "patellar tendon" RELATED [] xref: FMA:44581 ! Patellar ligament xref: GAID:128 ! patellar ligament xref: ncithesaurus:Patellar_Ligament ! Patellar Ligament xref: galen:LigamentumPatellae ! ligamentum patellae xref: EMAPA:18509 ! ligamentum patellae of knee joint primordium xref: EMAPA:19139 ! ligamentum patellae of knee joint xref: MESH:A02.513.514.475 ! patellar ligament is_a: UBERON:0000211 ! ligament relationship: connects UBERON:0000979 ! tibia relationship: connects UBERON:0002446 ! patella relationship: part_of UBERON:0001485 {source="FMA"} ! knee joint xref: SCTID:244639004 ! Entire patellar ligament xref: UMLS:C0206332 [Term] id: UBERON:0011112 name: tibiofibular joint def: "A joint that connects the tibia and the fibula." [UBERON:cjm, Wikipedia:Tibiofibular_joint] comment: Editor notes: we include location as part of the logical definition to prevent accidental classification of ankle joints as tibiofibular joints synonym: "tibiafibular joint" EXACT [] synonym: "fibulotibial joint" EXACT [] synonym: "fibulatibial joint" EXACT [] is_a: UBERON:0002210 {source="FMA"} ! syndesmosis intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0001446 ! fibula intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod xref: FMA:35181 ! tibiofibular joint xref: SCTID:244554002 ! Entire tibiofibular joint [Term] id: UBERON:0011113 name: inferior tibiofibular joint def: "The inferior tibiofibular articulation (tibiofibular syndesmosis) is formed by the rough, convex surface of the medial side of the lower end of the fibula, and a rough concave surface on the lateral side of the tibia. Below, to the extent of about 4 mm. these surfaces are smooth, and covered with cartilage, which is continuous with that of the ankle-joint. The ligaments are: Anterior ligament of the lateral malleolus, Posterior ligament of the lateral malleolus, Inferior transverse ligament of the tibiofibular syndesmosis, Interosseous ligament" [Wikipedia:Inferior_tibiofibular_articulation] synonym: "distal tibiofibular joint" EXACT [FMA:10465] synonym: "syndesmosis tibiofibularis" EXACT LATIN [FMA:TA] synonym: "tibiofibular syndesmosis" EXACT [FMA:10465] synonym: "inferior tibiofibular articulation" RELATED [Wikipedia:Inferior_tibiofibular_articulation] is_a: UBERON:0011112 {source="FMA"} ! tibiofibular joint relationship: connects UBERON:0004410 ! distal epiphysis of fibula relationship: connects UBERON:0000979 {notes="lateral side"} ! tibia xref: FMA:10465 ! inferior tibiofibular joint xref: SCTID:182209000 ! Entire distal tibiofibular joint [Term] id: UBERON:0011117 name: superior tibiofibular joint def: "The superior tibiofibular articulation is an arthrodial joint between the lateral condyle of the tibia and the head of the fibula. The contiguous surfaces of the bones present flat, oval facets covered with cartilage and connected together by an articular capsule and by anterior and posterior ligaments. When the term \"tibiofibular articulation\" is used without a modifier, it refers to the superior, and not the inferior tibiofibular articulation." [Wikipedia:Superior_tibiofibular_joint] synonym: "tibiofibular joint" BROAD [Wikipedia:Superior_tibiofibular_joint] synonym: "proximal tibiofibular joint" RELATED [Wikipedia:Superior_tibiofibular_joint] synonym: "superior tibiofibular articulation" RELATED [Wikipedia:Superior_tibiofibular_joint] synonym: "articulatio tibiofibularis" RELATED LATIN [Wikipedia:Superior_tibiofibular_joint] synonym: "proximal tibiofibular joint" EXACT [FMA:35184] intersection_of: UBERON:0011112 ! tibiofibular joint intersection_of: connects UBERON:0008775 ! proximal epiphysis of fibula intersection_of: connects UBERON:0009985 ! lateral condyle of femur xref: FMA:35184 ! superior tibiofibular joint xref: SCTID:182208008 ! Entire proximal tibiofibular joint xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a8/Gray347.png/250px-Gray347.png [Term] id: UBERON:0002211 name: nerve root comment: we make nerve root continuous_with nerve to avoid inconsistencies with the spatial disjointness constraint between PNS and CNS, with nerves part_of CNS. FMA has segment of nerve with subtypes: segment of sympathetic trunk, nerve root, nerve rootlet, nerve root proper subset: uberon_slim xref: FMA:5981 ! nerve root xref: BTO:0000883 ! spinal root is_a: UBERON:0000063 ! organ segment relationship: continuous_with UBERON:0001021 ! nerve xref: ncithesaurus:Nerve_Root ! Nerve Root xref: SCTID:362295007 ! Entire nerve root xref: UMLS:C0228084 [Term] id: UBERON:0002213 name: cartilaginous joint def: "Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]" [Wikipedia:Cartilaginous_joint, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "articulatio cartilaginea" EXACT [] xref: FMA:7496 ! Cartilaginous joint xref: MA:0000320 ! cartilaginous joint xref: ZFA:0005155 ! cartilaginous joint is_a: UBERON:0011134 {source="FMA"} ! nonsynovial joint xref: SCTID:58442004 ! Entire cartilaginous joint xref: TAO:0005155 ! cartilaginous joint synonym: "junctura cartilaginea" RELATED LATIN [Wikipedia:Cartilaginous_joint] [Term] id: UBERON:0002215 name: synchondrosis def: "Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA]" [Wikipedia:Synchondrosis, FMA:FMA] comment: Editor's note: WP considers epiphyseal plates as subtypes of this // consider adding link to hyaline cartilage subset: uberon_slim synonym: "epiphysial cartilage" RELATED [FMA:7497] synonym: "primary cartilaginous joint" EXACT [FMA:7497] xref: FMA:7497 ! Synchondrosis xref: MA:0001501 ! synchondrosis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/76/Gray297.png/200px-Gray297.png is_a: UBERON:0002209 {source="MA"} ! fibrous joint is_a: UBERON:0002213 ! cartilaginous joint synonym: "cartilago epiphysialis" EXACT LATIN [FMA:TA, FMA:7497] xref: SCTID:42903008 ! Entire synchondrosis xref: http://upload.wikimedia.org/wikipedia/commons/7/76/Gray297.png [Term] id: UBERON:0002216 name: symphysis def: "Cartilaginous joint in which the articulating bones or cartilages are connected by fibrocartilage. Examples: pubic symphysis, intervertebral symphysis, manubriosternal joint.[FMA]" [Wikipedia:Symphysis, FMA:FMA] comment: Editors note: consider adding fibrocartilage class subset: uberon_slim synonym: "secondary cartilaginous joint" EXACT [FMA:7498] xref: FMA:7498 ! Symphysis xref: MA:0001504 ! symphysis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Gray298.png/200px-Gray298.png is_a: UBERON:0002209 {source="MA"} ! fibrous joint is_a: UBERON:0002213 {source="FMA"} ! cartilaginous joint xref: SCTID:1584001 ! Entire symphysis xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray298.png [Term] id: UBERON:0008115 ! surface of cartilage name: surface of cartilage synonym: "cartilage surface" EXACT [FMA:76668] xref: FMA:76668 ! surface of cartilage is_a: UBERON:0006984 ! anatomical surface [Term] id: UBERON:0008124 name: joint articular surface comment: note that FMA has multiple "Articular surface of X" classes, with no way to group them xref: MA:0001518 ! joint articular surface is_a: UBERON:0008115 ! surface of cartilage relationship: part_of UBERON:0002217 {source="MA"} ! synovial joint [Term] id: UBERON:0008187 name: hypertrophic cartilage zone comment: see also VSAO:0000098 ! hypertrophic chondrocyte xref: MA:0002849 ! hypertrophic cartilage zone is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0004763 {source="MA"} ! endochondral bone tissue [Term] id: UBERON:0002219 name: subfornical organ def: "Group of neurons situated on the ventral surface of the fornix at the level of the foramen of Monro in the third ventricle (adapted from Wikipedia via NIF)." [Wikipedia:Subfornical_organ, NIF_GrossAnatomy:nlx_anat_100314] comment: Function notes: induces drinking behavior after stimulation with angiotensin II[MESH]. subset: uberon_slim xref: FMA:75260 ! Subfornical organ xref: GAID:795 ! subfornical organ xref: MA:0000940 ! subfornical organ xref: NIF_GrossAnatomy:nlx_anat_100314 ! Subfornical organ xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d7/Gray715.png/200px-Gray715.png xref: MESH:A08.713.840 ! subfornical organ xref: ABA:SFO ! Subfornical organ is_a: UBERON:0010135 {source="MA"} ! sensory circumventricular organ is_a: UBERON:0002663 {source="MA"} ! septal nuclear complex relationship: spatially_disjoint_from UBERON:0002690 {source="ABA"} ! anteroventral periventricular nucleus relationship: spatially_disjoint_from UBERON:0001934 {source="ABA"} ! dorsomedial nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002625 {source="ABA"} ! median preoptic nucleus relationship: spatially_disjoint_from UBERON:0002689 {source="ABA"} ! supraoptic crest relationship: spatially_disjoint_from UBERON:0007626 {source="ABA"} ! subparaventricular zone relationship: spatially_disjoint_from UBERON:0002034 {source="ABA"} ! suprachiasmatic nucleus synonym: "organum subfornicale" RELATED LATIN [Wikipedia:Subfornical_organ] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png [Term] id: UBERON:0002221 name: fontanelle def: "Anatomical structure that is a membranous gap between bones of the skull[TAO]. In humans: Fontanelles are soft spots on a baby's head which, during birth, enable the bony plates of the skull to flex, allowing the child's head to pass through the birth canal. The ossification of the bones of the skull cause the fontanelles to close over by a child's second birthday. The closures eventually form the sutures of the neurocranium. Although there are the two anterior and posterior fontanelles, there are two more fontanelles of interest, the mastoid fontanelle, and the sphenoidal fontanelle[WP]." [Wikipedia:Fontanelle] subset: uberon_slim subset: vertebrate_core synonym: "fontanel" EXACT [] xref: FMA:75438 ! Fontanelle xref: MA:0001465 ! fontanel xref: TAO:0001738 ! fontanel xref: ncithesaurus:Fontanelle ! Fontanelle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/Gray197.png/200px-Gray197.png xref: ZFA:0005536 ! fontanel xref: SCTID:272681004 ! Entire fontanel of skull is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001703 {source="ZFA", source="MA"} ! neurocranium relationship: adjacent_to UBERON:0003685 ! cranial suture synonym: "fonticuli cranii" RELATED LATIN [Wikipedia:Fontanelle] xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/Gray197.png property_value: external_definition "Anatomical structure that is a membranous gap between bones of the skull.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001738", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "fontanelles" EXACT PLURAL [TAO:0001738] synonym: "fontanels" EXACT PLURAL [TAO:0001738] xref: UMLS:C0224548 [Term] id: UBERON:0007862 name: perichordal tissue def: "Fibrous connective tissue that surrounds the notochord; includes a layer of elastin." [VSAO:curator] comment: Derived from cells surrounding the notochord (possibly the slerotome). Disparate from (not derived from) notochord. synonym: "notochord" RELATED [VSAO:curator] synonym: "perichordal connective tissue" EXACT [ZFA:0001633] synonym: "perichordal sheath" EXACT [VSAO:curator] synonym: "perichordal sheath tissue" EXACT [VSAO:curator] synonym: "perichordal tube" RELATED [ISBN10:0073040584] xref: VSAO:0000054 ! perichordal tissue xref: ZFA:0001633 ! perichordal connective tissue is_a: UBERON:0002384 {source="VSAO"} ! connective tissue relationship: surrounds UBERON:0002328 {source="VSAO-modified"} ! notochord relationship: develops_from UBERON:0003089 {source="Kardong"} ! sclerotome xref: AAO:0010446 ! perichordal connective tissue xref: AAO:0000737 ! perichordal tube xref: XAO:0004050 ! perichordal tissue xref: TAO:0001642 ! perichordal connective tissue property_value: external_definition "Portion of connective tissue which surrounds the notochord.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001642", date_retrieved="2012-08-14", source="TAO:wd"} property_value: axiom_lost_from_external_ontology "relationship type change: part_of notochord (VSAO:0000032) CHANGED TO: surrounds notochord (UBERON:0002328)[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000054", date_retrieved="2012-08-14"} [Term] id: UBERON:0011675 name: perichordal ring def: "Enlarged section of perichordal tube that is arranged serially but out of phase with segmental musculature." [ISBN10:0073040584] is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0007862 {source="AAO"} ! perichordal tissue xref: AAO:0000738 ! perichordal ring [Term] id: UBERON:0002222 name: perichondrium def: "Fibrous connective tissue that surrounds cartilage." [Wikipedia:Perichondrium, VSAO:0000036] subset: uberon_slim subset: vertebrate_core synonym: "cartilage connective tissue" RELATED [] synonym: "perichondral region of cartilage" RELATED [] synonym: "perichondral region of cartilage element" RELATED [] xref: FMA:75446 ! Perichondrium xref: TAO:0001643 ! perichondrium xref: ZFA:0001634 ! perichondrium xref: VSAO:0000036 ! perichondrium is_a: UBERON:0002384 {source="VSAO"} ! connective tissue relationship: surrounds UBERON:0007844 ! cartilage element xref: BTO:0005089 ! perichondrium xref: AAO:0010445 ! perichondrium xref: SCTID:11881003 ! Perichondrium xref: XAO:0004049 ! perichondrium xref: MA:0003008 ! perichondrium property_value: external_definition "Portion of connective tissue which surrounds cartilage.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001643", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0008304 name: inner chondrogenic layer of perichondrium def: "The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The chondrogenic layer remains undifferentiated and can form chondroblasts or chondrocytes." [Wikipedia:The_Free_Encyclopedia] is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0002222 {source="BTO"} ! perichondrium xref: BTO:0005090 ! inner chondrogenic layer of perichondrium [Term] id: UBERON:0008305 name: outer fibrous layer of perichondrium def: "The perichondrium consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibers." [Wikipedia:The_Free_Encyclopedia] is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0002222 {source="BTO"} ! perichondrium xref: BTO:0005091 ! outer fibrous layer of perichondrium [Term] id: UBERON:0002224 name: thoracic cavity def: "Body cavity subdivision which is enclosed by the thoracic wall and the diaphragm[FMA]." [Wikipedia:Thoracic_cavity, FMA:7565] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] synonym: "pectoral cavity" EXACT [] synonym: "space of thoracic compartment" EXACT [FMA:7565] xref: FMA:7565 ! Thoracic cavity xref: GAID:93 ! thoracic cavity xref: MA:0000032 ! thoracic cavity xref: OpenCyc:Mx4rmvyleLfEEduAAAACs6hRXg xref: OpenCyc:Mx4rvhU_TpwpEbGdrcN5Y29ycA xref: ncithesaurus:Thoracic_Cavity ! Thoracic Cavity xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Scheme_body_cavities-en.svg/200px-Scheme_body_cavities-en.svg.png xref: MESH:A01.911.800 ! thoracic cavity is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0000915 ! thoracic segment of trunk xref: SCTID:243949006 ! Entire thoracic cavity synonym: "cavitas thoracis" RELATED LATIN [Wikipedia:Thoracic_cavity] xref: http://upload.wikimedia.org/wikipedia/commons/c/ce/Gray846.png xref: UMLS:C0230139 [Term] id: UBERON:0002225 name: costal arch def: "The costal margin, sometimes referred to as the costal arch, is the medial margin formed by the false ribs -- specifically, from the eighth rib to the tenth rib." [Wikipedia:Costal_margin] comment: todo - split? check part_of relationship synonym: "arcus costae" RELATED [Wikipedia:Costal_margin] synonym: "subcostal arch" RELATED [Wikipedia:Costal_margin] synonym: "costal margin" RELATED [Wikipedia:Costal_margin] xref: FMA:7569 ! Costal arch xref: FMA:7570 ! costal margin xref: MA:0001396 ! costal arch xref: ncithesaurus:Costal_Arch ! Costal Arch is_a: UBERON:0006800 {source="FMA"} ! anatomical line relationship: part_of UBERON:0002228 {source="MA"} ! rib xref: SCTID:367767002 ! Entire costal arch synonym: "arcus costalis" RELATED LATIN [Wikipedia:Costal_margin] xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Gray115.png xref: UMLS:C0230143 [Term] id: UBERON:0002233 name: tectorial membrane of cochlea def: "The tectorial membrane (TM) is one of two acellular gels in the cochlea of the inner ear, the other being the basilar membrane (BM). The TM is located above the sulcus spiralis internus and the spiral organ of Corti and extends along the longitudinal length of the cochlea parallel to the BM. Radially the TM is divided into three zones, the limbal, middle and marginal zones. Of these the limbal zone is the thinnest (transversally) and overlies the auditory teeth of Huschke with its inside edge attached to the spiral limbus. The marginal zone is the thickest (transversally) and is divided from the middle zone by Hensen's Stripe. It overlies the sensory inner hair cells and electrically-motile outer hair cells of the organ of Corti and during acoustic stimulation stimulates the inner hair cells through fluid coupling, and the outer hair cells via direct connection to their tallest stereocilia." [Wikipedia:Tectorial_membrane_%28cochlea%29] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "tectorial membrane" EXACT [] synonym: "tectorial membrane of spiral organ of cochlea" EXACT [] xref: FMA:75805 ! Tectorial membrane of cochlea xref: GAID:876 ! tectorial membrane xref: MA:0001199 ! tectorial membrane xref: NIF_GrossAnatomy:birnlex_2531 ! Tectorial membrane of spiral organ of cochlea xref: ncithesaurus:Tectorial_Membrane ! Tectorial Membrane xref: MESH:A09.246.631.246.292.906 ! tectorial membrane is_a: UBERON:0005764 {source="Wikipedia"} ! acellular membrane relationship: part_of UBERON:0001855 ! cochlear duct of membranous labyrinth relationship: attaches_to UBERON:0002276 {notes="limbal zone"} ! lamina of spiral limbus xref: SCTID:368960006 ! Entire tectorial membrane xref: UMLS:C0039432 [Term] id: UBERON:0002226 name: basilar membrane of cochlea def: "a stiff structural element that separates two liquid-filled tubes that run along the coil of the cochlea, the scala media and the scala tympani[WP]." [Wikipedia:Basilar_membrane] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "basilar membrane" EXACT [MA:0001190] synonym: "lamina basilaris ductus cochlearis" RELATED LATIN [Wikipedia:Basilar_membrane] xref: FMA:75706 ! Basilar membrane of cochlea xref: GAID:872 ! basilar membrane xref: MA:0001190 ! basilar membrane xref: NIF_GrossAnatomy:birnlex_2521 ! Basilar membrane xref: ncithesaurus:Basilar_Membrane ! Basilar Membrane xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9b/Organ_of_corti.svg/200px-Organ_of_corti.svg.png xref: MESH:A09.246.631.246.125 ! basilar membrane is_a: UBERON:0005764 {source="Wikipedia"} ! acellular membrane relationship: part_of UBERON:0001855 ! cochlear duct of membranous labyrinth relationship: adjacent_to UBERON:0001864 ! scala tympan relationship: adjacent_to UBERON:0002295 ! scala media xref: SCTID:362574003 ! Entire basilar membrane of cochlea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Cochlea-crosssection.png/250px-Cochlea-crosssection.png xref: http://upload.wikimedia.org/wikipedia/commons/9/9b/Organ_of_corti.svg xref: UMLS:C0004816 [Term] id: UBERON:0002227 name: spiral organ of cochlea def: "The organ of Corti (or spiral organ) is the organ in the inner ear of mammals that contains auditory sensory cells, or 'hair cells.' [WP,unvetted]." [Wikipedia:Organ_of_Corti] subset: uberon_slim synonym: "cochlear spiral organ" EXACT [] synonym: "organ of Corti" RELATED [] synonym: "spiral organ" EXACT [] synonym: "spiral organ of Corti" EXACT [] synonym: "basilar papilla" RELATED [BTO:0001691] synonym: "Corti's organ" RELATED [BTO:0001691] synonym: "organum spirale" EXACT LATIN [Wikipedia:Organ_of_Corti] synonym: "papilla basilaris" EXACT [XAO:0003145] xref: FMA:75715 ! Spiral organ of cochlea xref: GAID:772 ! organ of corti xref: MA:0001193 ! spiral organ xref: NIF_GrossAnatomy:birnlex_2526 ! Spiral organ of Corti xref: ncithesaurus:Organ_of_Corti ! Organ of Corti xref: ncithesaurus:Spiral_Organ_of_Corti ! Spiral Organ of Corti xref: BTO:0001691 ! spiral organ xref: EFO:0001364 ! organ of corti xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Cochlea-crosssection.png/200px-Cochlea-crosssection.png xref: EMAPA:19061 ! organ of Corti xref: EMAPA:19151 ! spiral organ of Corti xref: XAO:0003145 ! basilar papilla xref: EV:0100364 ! spiral organ of Corti is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001855 {source="MA"} ! cochlear duct of membranous labyrinth relationship: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: has_part CL:0000202 ! auditory hair cell xref: AAO:0011018 ! basilar papilla xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Cochlea-crosssection.svg property_value: external_definition "A sensory structure in the lagenar portion of an amphibian's membranous labyrinth between the oval and round windows.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011018", date_retrieved="2012-06-20", source="XAO:curator"} xref: SCTID:279841009 ! Entire spiral organ of Corti xref: VHOG:0001567 ! spiral organ of Corti property_value: homology_notes "The auditory hair cells in tetrapods are located in the inner ear in a structure known as the basilar papilla. In mammals this structure (along with some related structure) is called the organ of Corti.[well established][VHOG]" xsd:string {external_class="VHOG:0001567", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.33", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0029207 [Term] id: UBERON:0006288 name: rib cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:17678 ! rib cartilage condensation xref: EHDAA2:0001716 ! rib cartilage condensation xref: VHOG:0001122 ! rib cartilage condensation xref: EHDAA:8347 ! rib cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0006289 {source="EHDAA2"} ! rib pre-cartilage condensation relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: develops_into UBERON:0002228 ! rib [Term] id: UBERON:0006289 name: rib pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:17397 ! rib pre-cartilage condensation xref: EHDAA2:0001717 ! rib pre-cartilage condensation xref: VHOG:0000681 ! rib pre-cartilage condensation xref: EHDAA:6026 ! rib pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: develops_into UBERON:0002228 ! rib relationship: develops_from UBERON:0003089 {source="EHDAA2-abduced", source="ZFA"} ! sclerotome [Term] id: UBERON:0002228 name: rib def: "An intersegmental rod-shaped bone that forms in the peritoneal membrane and attach to the vertebral parapophyses. They protect and support internal organs. In most vertebrates, ribs surround the chest. they enable lungs to expand by expanding the chest, they also protect the lungs, heart, and other internal organs of the thorax. In some animals, especially snakes, ribs may provide support and protection for the entire body." [Wikipedia:Rib, ZFIN:curator] comment: Humans have 24 ribs (12 pairs). The first seven sets of ribs, known as "true ribs", are directly attached to the sternum through the costal cartilage. The following five sets are known as "false ribs", three of these sharing a common cartilaginous connection to the sternum, while the last two (eleventh and twelfth ribs) are termed floating ribs (costae fluitantes) or vertebral ribs. They are attached to the vertebrae only, and not to the sternum or cartilage coming off of the sternum. Some people are missing one of the two pairs of floating ribs, while others have a third pair. Rib removal is the surgical excision of ribs for therapeutic or cosmetic reasons. In fish, there are often two sets of ribs attached to the vertebral column. One set, the dorsal ribs, are found in the dividing septum between the upper and lower parts of the main muscle segments, projecting roughly sideways from the vertebral column. The second set, of ventral ribs arise from the vertebral column just below the dorsal ribs, and enclose the lower body, often joining at the tips. Not all species possess both types of rib, with the dorsal ribs being most commonly absent. Sharks, for example, have no dorsal ribs, and only very short ventral ribs, while lampreys have no ribs at all. In some teleosts, there may be additional rib-like bones within the muscle mass. Tetrapods, however, only ever have a single set of ribs which are probably homologous with the dorsal ribs of fishes. In the early tetrapods, every vertebra bore a pair of ribs, although those on the thoracic vertebrae are typically the longest. The sacral ribs were stout and short, since they formed part of the pelvis, connecting the backbone to the hip bones.[1] In most subsequent forms, many of these early ribs have been lost, and in living amphibians and reptiles, there is great variation in rib structure and number. For example, turtles have only eight pairs of ribs, which are developed into a bony or cartilagenous carapace and plastron, while snakes have numerous ribs running along the full length of their trunk. Frogs typically have no ribs, aside from a sacral pair, which form part of the pelvis.[1]. In birds, ribs are present as distinct bones only on the thoracic region, although small fused ribs are present on the cervical vertebrae. The thoracic ribs of birds possess a wide projection to the rear; this uncinate process is an attachment for the shoulder muscles.[1]. Mammals usually also only have distinct ribs on the thoracic vertebra, although fixed cervical ribs are also present in monotremes. In marsupials and placental mammals, the cervical and lumbar ribs are found only as tiny remnants fused to the vertebrae, where they are referred to as transverse processes. In general, the structure and number of the true ribs in humans is similar to that in other mammals. Unlike reptiles, caudal ribs are never found in mammals.[1] subset: uberon_slim subset: vertebrate_core synonym: "dorsal rib" RELATED [] synonym: "pleural rib" RELATED [] xref: AAO:0000545 ! rib xref: FMA:7574 ! Rib xref: GAID:245 ! rib xref: VHOG:0001154 ! rib xref: MA:0000315 ! rib xref: OpenCyc:Mx4rvVjNoZwpEbGdrcN5Y29ycA xref: TAO:0000538 ! rib xref: ZFA:0000538 ! rib xref: ncithesaurus:Rib ! Rib xref: galen:Rib ! rib xref: OpenCyc:Mx4rvVjNoZwpEbGdrcN5Y29ycA ! rib xref: EMAPA:18010 ! rib xref: MESH:A02.835.232.904.567 ! rib xref: EFO:0003066 ! rib is_a: UBERON:0002495 ! long bone relationship: part_of UBERON:0003252 ! rib cage relationship: in_lateral_side_of UBERON:0003252 {source="FMA-abduced-lr"} ! rib cage xref: SCTID:302523002 ! Entire rib relationship: develops_from UBERON:0006288 {evidence="definitional"} ! rib cartilage condensation property_value: external_definition "Endochondral, rodlike element that articulates with the transverse process and parapophysis (double-headed rib), or with the transverse process only (single-headed rib); it extends into the body wall and provides a site for muscle attachment.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000545", date_retrieved="2012-06-20", source="AAO:Pugener_2002"} property_value: external_definition "Endochondral bone that is intersegmental and rod-shaped, forming in the peritoneal membrane and attached to the vertebral parapophyses. Ribs protect and support internal organs.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000538", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "ribs" RELATED PLURAL [TAO:0000538] property_value: has_relational_adjective "costal" xsd:string xref: UMLS:C0035561 [Term] id: UBERON:0010388 ! proximal segment of rib name: proximal segment of rib def: "The segment of the rib that connects to a vertebra[MP]. a small part of the rib composed of the head, neck, tuberculum and a short proximal part of the body[PMID]" [MP:0000152, PMID:15906248] comment: The proximal rib derives from the caudal half of somite[PMID:15906248] synonym: "proximal rib" EXACT [MA:0001400] synonym: "proximal part of rib" EXACT [PMID:15906248] synonym: "vertebral part of rib" RELATED [] synonym: "costal part of rib" RELATED [] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0002228 {source="MA"} ! rib relationship: connected_to UBERON:0002412 ! vertebra xref: MA:0001400 ! proximal rib [Term] id: UBERON:0010424 name: distal segment of rib comment: The distal rib derives from both somite halves[PMID:15906248] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0002228 {source="MA"} ! rib xref: MA:0001397 ! distal rib synonym: "distal rib" EXACT [MA:0001397] synonym: "distal part of rib" EXACT [PMID:15906248] synonym: "sternal rib" NARROW [] synonym: "vertical segment of rib" NARROW [] [Term] id: UBERON:0002230 ! head of rib name: head of rib def: "The head of the rib is the end of a rib closest to the vertebral column, with which it articulates with. It is marked by a kidney-shaped articular surface, divided by a horizontal crest into two facets for articulation with the depression formed on the bodies of two adjacent thoracic vertebrae; the upper facet is the smaller; to the crest is attached the interarticular ligament. [WP,unvetted]." [Wikipedia:Head_of_rib] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "rib head" EXACT [] xref: FMA:7575 ! Head of rib xref: MA:0001415 ! rib head xref: ncithesaurus:Rib_Head ! Rib Head xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Gray122.png/200px-Gray122.png is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0010388 {source="PMID:15906248"} ! proximal segment of rib relationship: connected_to UBERON:0002412 ! vertebra xref: SCTID:263358001 ! Entire head of rib synonym: "caput costae" RELATED LATIN [Wikipedia:Head_of_rib] xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray122.png xref: UMLS:C0222806 [Term] id: UBERON:0003253 name: neck of rib def: "The neck of the rib is the flattened portion which extends lateralward from the head; it is about 2.5 cm. long, and is placed in front of the transverse process of the lower of the two vertebrC& with which the head articulates. Its anterior surface is flat and smooth, its posterior rough for the attachment of the ligament of the neck, and perforated by numerous foramina. Of its two borders the superior presents a rough crest (crista colli costE) for the attachment of the anterior costotransverse ligament; its inferior border is rounded. On the posterior surface at the junction of the neck and body, and nearer the lower than the upper border, is an eminencebthe tubercle; it consists of an articular and a non-articular portion. The articular portion, the lower and more medial of the two, presents a small, oval surface for articulation with the end of the transverse process of the lower of the two vertebrC& to which the head is connected. The non-articular portion is a rough elevation, and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper than in the lower ribs." [Wikipedia:Neck_of_rib] intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0002228 ! rib relationship: part_of UBERON:0010388 {source="PMID:15906248"} ! proximal segment of rib synonym: "rib neck" EXACT [FMA:7576] synonym: "collum costae" EXACT [Wikipedia:Neck_of_rib] xref: FMA:7576 ! neck of rib xref: SCTID:263359009 ! Entire neck of rib synonym: "collum costae" RELATED LATIN [Wikipedia:Neck_of_rib] xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray122.png [Term] id: UBERON:0002231 name: body of rib comment: This class was created automatically from a combination of ontologies synonym: "rib body" EXACT [] synonym: "rib shaft" EXACT [] synonym: "shaft of rib" EXACT [] xref: FMA:7577 ! Body of rib xref: MA:0001416 ! rib shaft xref: ncithesaurus:Rib_Shaft ! Rib Shaft is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0010388 {source="PMID:15906248"} ! proximal segment of rib xref: SCTID:263361000 ! Entire shaft of rib xref: UMLS:C0448161 [Term] id: UBERON:0011651 name: ventral head of rib def: "Ventral head of a bicapitate rib. It articulates with the parapophysis[AAO]." [AAO:0000723] comment: Taxon notes: Ribs of primitive tetrapods are bicipital (having two heads)[Kardong]. synonym: "capitulum of rib" EXACT [AAO:0000723] synonym: "capitulum" NARROW [] synonym: "costal capitulum" EXACT [] synonym: "capitulum of costa" EXACT [] intersection_of: UBERON:0002230 ! head of rib intersection_of: connected_to UBERON:0003109 ! parapophysis xref: AAO:0000723 ! capitulum of rib [Term] id: UBERON:0011652 name: dorsal head of rib def: "Dorsal head of a bicapitate rib. It articulates with the diapophysis[AAO]." [AAO:0000722] comment: Taxon notes: Ribs of primitive tetrapods are bicipital (having two heads)[Kardong]. Terminology notes: sometimes called the tuberculum, but not to be confused with the tubercle, which is between body and neck synonym: "tuberculum" BROAD [AAO:0000722] synonym: "tuberculum of rib" EXACT [] intersection_of: UBERON:0002230 ! head of rib intersection_of: connected_to UBERON:0011653 ! diapophysis of rib xref: AAO:0000722 ! tuberculum disjoint_from: UBERON:0002235 ! tubercle of rib [Term] id: UBERON:0011653 ! diapophysis of rib name: diapophysis of rib def: "Paired processes that arise near the midpoint of the neural arch lamina, for the attachment of the tuberculum of two-headed ribs. Also called transverse processes. In anurans, the term diapophysis is used in reference to the modified transverse processes of the sacral vertebra elaborated for support of the pelvic girdle." [AAO:0000706] is_a: UBERON:0004529 {source="AAO"} ! anatomical projection relationship: part_of UBERON:0003861 {source="Kardong"} ! neural arch xref: AAO:0000706 ! diapophysis synonym: "diapophysis" EXACT [AAO:0000706] [Term] id: UBERON:0002235 name: tubercle of rib def: "The tubercle of a rib is an eminence on the posterior surface, at the junction of the neck and body of the rib, and nearer the lower than the upper border. It consists of an articular and a non-articular portion. The articular portion, the lower and more medial of the two, presents a small, oval surface for articulation with the end of the transverse process of the lower of the two vertebrae to which the head is connected. The non-articular portion is a rough elevation, and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper than in the lower ribs[WP]." [Wikipedia:Tubercle_(rib)] subset: uberon_slim synonym: "rib tubercle" EXACT [] xref: FMA:7583 ! Tubercle of rib xref: MA:0001417 ! rib tubercle xref: ncithesaurus:Rib_Tubercle ! Rib Tubercle intersection_of: UBERON:0005813 ! tubercle intersection_of: part_of UBERON:0002231 ! body of rib relationship: part_of UBERON:0002231 {source="FMA"} ! body of rib relationship: part_of UBERON:0010388 {source="PMID:15906248"} ! proximal segment of rib xref: SCTID:361104005 ! Entire tubercle of rib xref: UMLS:C0222809 [Term] id: UBERON:0007843 name: uncinate process of ribs def: "A posterior projection from proximal rib segments. Offers attachment sites for respiratory and shoulder muscles as well as adding structural support to the trunk skeleton[Kardong 2012]." [Wikipedia:Uncinate_processes_of_ribs, ISBN10:0073040584, PHENOSCAPE:ad] comment: WP: Although bony uncinate processes are unique to birds, cartilaginous uncinate processes are present in crocodiles. The uncinate process has also been reported in Sphenodon, Caudipteryx, oviraptorids, Confuciusornis and Chaoyangia however it does not occur in Archaeopteryx synonym: "uncinate process" BROAD INCONSISTENT [AAO:0000741] xref: AAO:0000741 ! uncinate process is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0010388 {source="Kardong"} ! proximal segment of rib relationship: never_in_taxon NCBITaxon:8827 {source="PMID:15755883"} ! Anhimidae disjoint_from: UBERON:0010373 ! uncinate process of pancreas disjoint_from: UBERON:0010372 ! uncinate process of ethmoid property_value: external_definition "Posteriorly directed process (occasionally directed anteriorly) usually associated with the rib (sometimes with the transverse process) of the third vertebra; they provide the origin of the mm serratus superior, medius, and inferior.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000741", date_retrieved="2012-06-20", source="AAO:Pugener_2002"} [Term] id: UBERON:0010372 ! uncinate process of ethmoid name: uncinate process of ethmoid def: "In the ethmoid bone, a curved lamina, the uncinate process, projects downward and backward from this part of the labyrinth; it forms a small part of the medial wall of the maxillary sinus, and articulates with the ethmoidal process of the inferior nasal concha." [Wikipedia:Uncinate_process_of_ethmoid_bone] synonym: "uncinate process" BROAD INCONSISTENT [SCTID:306373001] synonym: "processus uncinatus" RELATED [Wikipedia:Uncinate_process_of_ethmoid_bone] synonym: "uncinate process of the ethmoid" EXACT [Wikipedia:Uncinate_process_of_ethmoid_bone] synonym: "uncinate process of the ethmoid bone" EXACT [Wikipedia:Uncinate_process_of_ethmoid_bone] is_a: UBERON:0004529 {source="FMA"} ! anatomical projection xref: FMA:57455 ! uncinate process of ethmoid xref: SCTID:306373001 ! Uncinate process disjoint_from: UBERON:0010373 ! uncinate process of pancreas synonym: "processus uncinatus ossis ethmoidalis" RELATED LATIN [Wikipedia:Uncinate_process_of_ethmoid_bone] xref: http://upload.wikimedia.org/wikipedia/commons/c/ce/Processus_uncinatus_ossis_ethmoidalis.PNG [Term] id: UBERON:0012278 ! nasal gland name: nasal gland def: "The nasal glands are the seromucous glands in the respiratory region of the nasal mucous membrane. The three major types of nasal glands are anterior serous glands, seromucous glands, and Bowman glands." [Wikipedia:Nasal_glands] intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000004 ! olfactory apparatus relationship: part_of UBERON:0002330 ! exocrine system xref: SCTID:368881007 ! Entire nasal gland xref: ncithesaurus:Nose_Nasal_Cavity_Nasal_Gland_MMHCC ! mouse nasal gland xref: UMLS:C1522269 [Term] id: UBERON:0002232 name: olfactory gland def: "Bowman's glands (aka olfactory glands, glands of Bowman) are situated in the olfactory mucosa, beneath the olfactory epithelium, in the lamina propria, a connective tissue also containing fibroblasts, blood vessels, and bundles of fine axons from the olfactory neurons. The structure of the Bowman's glands consists of an acinus in the lamina propria and a secretory duct going out through the olfactory epithelium. Electron microscopy studies show that Bowman's glands contain cells with large secretory vesicles.[2] Bowman's glands might secrete proteins such as Lysozyme, amylase and IgA similarly to serous glands. The exact composition of the secretions from Bowman's glands is unclear, but there is evidence that Bowman's glands do not produce odorant binding protein[WP]." [Wikipedia:Olfactory_glands] synonym: "olfactory gland of Bowman" EXACT [] synonym: "Bowman's gland" RELATED [] xref: FMA:75801 ! Olfactory gland xref: MA:0000287 ! olfactory gland xref: BTO:0001697 ! olfactory gland is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0001997 ! olfactory epithelium xref: AAO:0010162 ! Bowman's gland xref: SCTID:368891001 ! Entire olfactory gland subset: organ_slim synonym: "glandulae olfactoriae" RELATED LATIN [Wikipedia:Olfactory_glands] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray857.png property_value: external_definition "Multicellular mucous glands of the olfactory epithelium, present only in adults.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010162", date_retrieved="2012-06-20", source="AAO:EJS"} [Term] id: UBERON:0013233 name: supraorbital gland def: "The supraorbital gland is a type of lateral nasal gland found in some species of marine birds, particularly penguins, which removes sodium chloride from the bloodstream. The gland's function is similar to that of the kidneys, though it is much more efficient at removing salt, allowing Penguins to survive without access to fresh water. Contrary to popular belief, the gland does not directly convert saltwater to freshwater. The term supraorbital refers to the area just above the eye socket (which is known as the orbit of the eye. ) Living in saltwater environments would naturally pose a large problem for penguins because the ingestion of saltwater would be detrimental to a penguin's health. Although penguins do not directly drink water, it is taken in when they engulf prey. As a result, saltwater enters their system and must be effectively excreted. The supraorbital gland has thus enabled the penguins' survival in such environments due to its water-filtering capability. The gland is located just above the eyes and surrounds a capillary in the head. This capillary constantly strains out the salt in the saltwater that a penguin takes in. Since the byproduct of the gland has roughly five times as much salt as would normally be found in the animal's fluids, the supraorbital gland is highly efficient. The penguin excretes the salt byproduct as a brine through its bill. Often, the fluid drips out, and this gives the appearance of a runny nose. However, the fluid may also be sneezed out. In the absence of saltwater, caused by captivity, the supraorbital gland will lie dormant as it has no other purpose. Having a dormant supraorbital gland does not negatively affect the health of a penguin." [Wikipedia:Supraorbital_gland] is_a: UBERON:0012278 ! nasal gland relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0000398 name: cartilage tissue of sternum def: "Any portion of cartilage tissue that is part of the sternum" [UBERON:cjm] comment: Examples: cartilage of manubrium, cartilage of xiphoid process synonym: "cartilage of sternum" EXACT [FMA:32567] xref: FMA:32567 ! Cartilage of sternum intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0000975 ! sternum [Term] id: UBERON:0002236 name: costal cartilage def: "The costal cartilages are bars of hyaline cartilage which serve to prolong the ribs forward and contribute very materially to the elasticity of the walls of the thorax. [WP,unvetted]." [Wikipedia:Costal_cartilage] synonym: "sternal cartilage" RELATED [BTO:0001721] subset: uberon_slim xref: FMA:7591 ! Costal cartilage xref: MA:0000106 ! costal cartilage xref: BTO:0001721 ! sternal cartilage xref: ncithesaurus:Costal_Cartilage ! Costal Cartilage xref: OpenCyc:Mx4rwP1g3pwpEbGdrcN5Y29ycA ! costal cartilage xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cc/Gray315.png/200px-Gray315.png synonym: "cartilago costalis" RELATED [BTO:0001721] is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0002228 ! rib xref: SCTID:244703004 ! Entire costal cartilage synonym: "cartilagines costales" RELATED LATIN [Wikipedia:Costal_cartilage] xref: http://upload.wikimedia.org/wikipedia/commons/c/cc/Gray315.png xref: UMLS:C0222787 [Term] id: UBERON:0002237 name: true rib def: "A rib that is ventrally connected to the sternum." [Wikipedia:True_ribs, ISBN10:0073040584] synonym: "costa vera" EXACT [] synonym: "costae verae" RELATED PLURAL [Wikipedia:True_ribs] xref: FMA:7592 ! True rib xref: MA:0001419 ! true rib xref: OpenCyc:Mx4rv4-iWJwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rv4-iWJwpEbGdrcN5Y29ycA ! true rib xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3d/Gray115.png/200px-Gray115.png intersection_of: UBERON:0002228 ! rib intersection_of: connected_to UBERON:0000975 ! sternum xref: SCTID:368044009 ! Entire true rib xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Gray115.png [Term] id: UBERON:0002238 name: false rib def: "A rib that is not directly ventrally connected to the sternum." [Wikipedia:False_rib, ISBN10:0073040584] subset: uberon_slim synonym: "asternal ribs" RELATED [Wikipedia:False_ribs] synonym: "costae spuriae" RELATED PLURAL [Wikipedia:False_ribs] synonym: "costa spuria" EXACT [] xref: FMA:7594 ! False rib xref: MA:0001398 ! false rib xref: OpenCyc:Mx4rwLzzTZwpEbGdrcN5Y29ycA ! false rib xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3d/Gray115.png/200px-Gray115.png is_a: UBERON:0002228 ! rib disjoint_from: UBERON:0002237 ! true rib xref: SCTID:368045005 ! Entire false rib [Term] id: UBERON:0002239 name: floating rib def: "A rib that is not connected to sternum or sternal cartilage." [Wikipedia:Floating_rib, ISBN10:0073040584] subset: uberon_slim synonym: "costa fluitante" EXACT LATIN [] synonym: "vertebral rib" EXACT [] xref: FMA:7595 ! Floating rib xref: MA:0001399 ! floating rib xref: OpenCyc:Mx4rvaPCWZwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvaPCWZwpEbGdrcN5Y29ycA ! floating rib xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f7/Skeleton_woman_back.png/200px-Skeleton_woman_back.png is_a: UBERON:0002238 ! false rib xref: SCTID:368046006 ! Entire floating rib synonym: "costae fluctuantes" RELATED LATIN [Wikipedia:Floating_rib] synonym: "costae fluitantes" RELATED LATIN [Wikipedia:Floating_rib] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Skeleton_woman_back.png [Term] id: UBERON:0002243 name: cutaneous vein def: "one of a number of veins in the subcutaneous tissue that empty into deep veins" [http://www.thefreedictionary.com/cutaneous+vein] comment: AO notes: GAT in FMA xref: FMA:76720 ! Cutaneous vein xref: MA:0002098 ! cutaneous vein xref: ncithesaurus:Cutaneous_Vein ! Cutaneous Vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0002072 ! hypodermis xref: UMLS:C1185726 [Term] id: UBERON:0011628 ! early premaxilla name: early premaxilla is_a: UBERON:0007842 {source="EHDAA2"} ! membrane bone relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest relationship: part_of UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme relationship: part_of UBERON:0003277 {source="EHDAA2"} ! skeleton of upper jaw relationship: part_of UBERON:0003113 {source="Kardong"} ! dermatocranium xref: EHDAA2:0001495 ! early premaxilla [Term] id: UBERON:0002244 ! premaxilla alt_id: UBERON:0002253 name: premaxilla def: "One of the bones of the upper jaw situated between and in front of the maxillae[VHOG]." [Wikipedia:Premaxilla, VHOG:0000426, Wikipedia:Incisive_bone] comment: Editors note: requires checking embryonic vs adult; isa fetal organ part in FMA; adult bone of upper jaw in AAO and ZFA; split. Note that we have loops if we add develops_from UBERON:0005620 {source="EHDAA2"} ! primary palate subset: uberon_slim subset: vertebrate_core synonym: "incisive bone" RELATED [Wikipedia:Incisive_bone] synonym: "premaxillae" EXACT PLURAL [] synonym: "premaxillary" EXACT [PHENOSCAPE:ad] synonym: "premaxillary bone" RELATED [Wikipedia:Premaxilla] synonym: "premaxilla bone" RELATED [Wikipedia:Premaxilla] synonym: "os incisivum" RELATED [Wikipedia:Premaxilla] xref: AAO:0000461 ! premaxilla xref: EHDAA:6962 ! premaxilla xref: EHDAA:8033 ! premaxilla xref: FMA:76869 ! Premaxilla xref: FMA:77231 ! Incisive bone xref: VHOG:0000426 ! premaxilla xref: MA:0001493 ! premaxilla xref: TAO:0000567 ! premaxilla xref: ZFA:0000567 ! premaxilla xref: EMAPA:17641 ! premaxilla of maxillary process xref: EMAPA:19033 ! premaxilla of skeleton of upper jaw xref: EMAPA:17933 ! premaxilla of upper jaw is_a: UBERON:0002514 ! intramembranous bone relationship: develops_from UBERON:0011628 ! early premaxilla relationship: part_of UBERON:0003277 {source="VHOG"} ! skeleton of upper jaw relationship: part_of UBERON:0011156 ! facial skeleton relationship: part_of UBERON:0003113 {source="Kardong"} ! dermatocranium property_value: external_definition "Paired, intramembranous bones located at the anterior end of the skull; they form the anterior-most segment of the maxillary arch.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000461", date_retrieved="2012-06-20", source="AAO:LAP"} xref: SCTID:308884009 ! Entire premaxillary bone xref: http://upload.wikimedia.org/wikipedia/commons/4/4a/Gray160.png property_value: external_definition "Dermal bone that forms the anteriormost element of the upper jaw. It articulates with the maxilla posterodorsally and its antimere medially. The premaxilla is paired.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000567", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps mesethmoid-premaxillary joint (TAO:0001676)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000567", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps inter-premaxillary joint (TAO:0001950)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000567", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps premaxillary-maxillary joint (TAO:0002260)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000567", date_retrieved="2012-08-14"} property_value: external_definition "One of the bones of the upper jaw situated between and in front of the maxillae. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000426", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) in all higher vertebrates a premaxilla is present (...) (reference 1); Although the presence of a tooth-bearing outer buccal arcade (premaxilla, maxilla, dentary) is cited as a common character of Osteichthyes, dipnoans lack all three bones (...) (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000426", ontology="VHOG", source="DOI:10.1017/S0022215100025585 O'Malley JF\, Evolution of the nasal cavities and sinuses in relation to function. The Journal of Laryngology and Otology (1924)\, ISBN:978-3540428541 Kapoor BG\, Bhavna Khanna\, Ichthyology Handbook (2004) p.105", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002245 name: hemisphere of cerebellum def: "A paired regions of the cerebellum that lie outside and lateral to the central vermis[MP]. The cerebellum consists of three parts, a median and two lateral, which are continuous with each other, and are substantially the same in structure. The median portion is constricted, and is called the vermis, from its annulated appearance which it owes to the transverse ridges and furrows upon it; the lateral expanded portions are named the hemispheres. The lateral hemisphere is considered the portion of the cerebellum to develop most recently. [WP,unvetted]." [Wikipedia:Cerebellar_hemisphere, MP:0009959] subset: uberon_slim synonym: "cerebellar hemispheres" RELATED PLURAL [] synonym: "cerebellar hemisphere" EXACT [] synonym: "cerebellum hemisphere" EXACT [] synonym: "hemisphere of cerebellum [H II - H X]" EXACT [] xref: FMA:76925 ! Hemisphere of cerebellum xref: MA:0000200 ! cerebellar hemisphere xref: NIF_GrossAnatomy:birnlex_1575 ! Cerebellar hemisphere xref: ABA:HEM ! Hemispheric regions is_a: UBERON:0002946 ! regional part of cerebellum relationship: part_of UBERON:0002129 ! cerebellar cortex relationship: in_lateral_side_of UBERON:0002037 ! cerebellum synonym: "hemispherium cerebelli [hII-hX]" EXACT LATIN [FMA:TA, FMA:76925] xref: ncithesaurus:Hemisphere_of_the_Cerebellum ! Hemisphere of the Cerebellum xref: SCTID:362411002 ! Entire cerebellar hemisphere synonym: "hemispherium cerebelli" RELATED LATIN [Wikipedia:Cerebellar_hemisphere] xref: http://upload.wikimedia.org/wikipedia/commons/4/43/CerebellumDiv.png xref: UMLS:C0228465 [Term] id: UBERON:0002246 name: dorsal thoracic nucleus def: "." [Wikipedia:Clarke's_column] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "Clarke's column" EXACT [] synonym: "Clarke's nucleus" EXACT [] synonym: "posterior thoracic nucleus" EXACT [] synonym: "spinal cord dorsal nucleus" EXACT [] synonym: "Stilling-Clarke's column" EXACT [] synonym: "Stilling-Clarke's nucleus" EXACT [] xref: FMA:77023 ! Dorsal thoracic nucleus xref: MA:0001121 ! spinal cord dorsal nucleus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002256 ! dorsal horn of spinal cord synonym: "nucleus thoracicus posterior" EXACT LATIN [FMA:TA, FMA:77023] [Term] id: UBERON:0010279 ! pericardial sinus name: pericardial sinus def: "There are two Pericardial sinuses: transverse and oblique. The cul-de-sac enclosed between the limbs of the inverted U of the venous mesocardium lies behind the left atrium and is known as the oblique sinus. . The passage between the venous and arterial mesocardiabi.e. , between the aorta and pulmonary artery in front and the superior vena cava behindbis termed the transverse sinus. Also, the sinus that forms in the pericardial cavity where the dorso-mesentary pericardium reside. Can be used to pass ligature during cardiac surgery." [Wikipedia:Pericardial_sinus] synonym: "oblique pericardial" RELATED [Wikipedia:Pericardial_sinus] synonym: "oblique pericardial sinus" RELATED [Wikipedia:Pericardial_sinus] synonym: "oblique sinus" RELATED [Wikipedia:Pericardial_sinus] synonym: "pericardial sinuses" RELATED [Wikipedia:Pericardial_sinus] synonym: "transverse pericardial" RELATED [Wikipedia:Pericardial_sinus] synonym: "transverse pericardial sinus" RELATED [Wikipedia:Pericardial_sinus] is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0010277 {source="MA-abduced"} ! mesocardium relationship: part_of UBERON:0001074 {source="FMA-abduced"} ! pericardial cavity xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png xref: SCTID:314273005 ! Pericardial sinus [Term] id: UBERON:0002248 name: transverse pericardial sinus def: "The passage between the venous and arterial mesocardia —i.e., between the aorta and pulmonary artery in front and the superior vena cava behind. Also, the sinus that forms in the pericardial cavity where the dorso-mesentary pericardium reside.[WP,unvetted]." [Wikipedia:Pericardial_sinus] subset: uberon_slim synonym: "Thiele's canal" EXACT [FMA:77132] synonym: "transverse sinus of pericardial cavity" EXACT [FMA:77132] synonym: "transverse sinus" BROAD [] xref: EHDAA:796 ! transverse pericardial sinus xref: FMA:77132 ! Transverse pericardial sinus xref: MA:0001880 ! transverse pericardial sinus xref: EHDAA2:0002077 ! transverse pericardial sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Gray489.png/200px-Gray489.png xref: EMAPA:16214 ! transverse pericardial sinus is_a: UBERON:0010279 ! pericardial sinus relationship: part_of UBERON:0005601 {source="MA"} ! dorsal mesocardium [Term] id: UBERON:0010283 name: oblique pericardial sinus def: "The cul-de-sac enclosed between the limbs of the inverted U of the venous mesocardium lies behind the left atrium.[WP,unvetted]." [Wikipedia:Pericardial_sinus] synonym: "oblique sinus of pericardial cavity" EXACT [FMA:77133] is_a: UBERON:0010279 ! pericardial sinus xref: FMA:77133 ! oblique pericardial sinus [Term] id: UBERON:0002249 name: median artery comment: This class was created automatically from a combination of ontologies xref: FMA:77142 ! Median artery xref: MA:0001999 ! median artery xref: ncithesaurus:Median_Artery ! Median Artery is_a: UBERON:0001637 ! artery xref: UMLS:C0687034 [Term] id: UBERON:0002250 name: popliteal artery def: "In human anatomy, the popliteal artery is defined as the extension of the 'superficial' femoral artery after passing through the adductor canal and adductor hiatus above the knee. The termination of the popliteal artery is its bifurcation into the anterior tibial artery and posterior tibial artery. The popliteal artery, through numerous smaller branches, supplies blood to the knee joint and muscles in the thigh and calf. It is accompanied, along its length, by the popliteal vein. [WP,unvetted]." [Wikipedia:Popliteal_artery] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:77155 ! Popliteal artery xref: GAID:504 ! popliteal artery xref: MA:0002021 ! popliteal artery xref: OpenCyc:Mx4rvduV6pwpEbGdrcN5Y29ycA xref: ncithesaurus:Popliteal_Artery ! Popliteal Artery xref: OpenCyc:Mx4rvduV6pwpEbGdrcN5Y29ycA ! popliteal artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a2/Popliteal_artery.png/200px-Popliteal_artery.png xref: MESH:A07.231.114.681 ! popliteal artery is_a: UBERON:0001637 ! artery xref: SCTID:181350008 ! Entire popliteal artery synonym: "arteria poplitea" RELATED LATIN [Wikipedia:Popliteal_artery] xref: http://upload.wikimedia.org/wikipedia/commons/a/a2/Popliteal_artery.png xref: UMLS:C0032649 [Term] id: UBERON:0002251 name: iliocostalis muscle def: "The iliocostalis is the muscle immediately lateral to the longissimus that is the nearest to the furrow that separates the epaxial muscles from the hypaxial. It lies very deep to the fleshy portion of the serratus ventralis (serratus anterior). [WP,unvetted]." [Wikipedia:Iliocostalis] synonym: "lateral column of erector spinae" RELATED [] synonym: "iliocostalis" EXACT [] synonym: "iliocostal muscle" EXACT [] synonym: "musculus iliocostalis" EXACT LATIN [Wikipedia:Iliocostalis] subset: uberon_slim xref: FMA:77177 ! Iliocostalis xref: MA:0002319 ! iliocostalis xref: ncithesaurus:Iliocostal_Muscle ! iliocostal muscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/89/Iliostalis.png/200px-Iliostalis.png xref: SCTID:244854008 ! Entire iliocostalis muscle is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column relationship: part_of UBERON:0002462 {source="Wikipedia"} ! erector spinae relationship: innervated_by UBERON:0006839 {source="dbpedia"} ! posterior ramus of spinal nerve relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="Ribs"} ! rib relationship: has_muscle_origin UBERON:0003690 {source="dbpedia", notes="Sacrum/Illiac Crest/Spinous Processes of lower lumbar/thoracic vertebrae"} ! sacrum relationship: has_muscle_origin UBERON:0001076 {source="dbpedia", notes="Sacrum/Illiac Crest/Spinous Processes of lower lumbar/thoracic vertebrae"} ! spinous process of vertebra xref: http://upload.wikimedia.org/wikipedia/commons/8/89/Iliostalis.png xref: UMLS:C0224304 [Term] id: UBERON:0008546 name: iliocostalis cervicis muscle def: "The iliocostalis cervicis (cervicalis ascendens) arises from the angles of the third, fourth, fifth, and sixth ribs, and is inserted into the posterior tubercles of the transverse processes of the fourth, fifth, and sixth cervical vertebrae.." [Wikipedia:Iliocostalis#Iliocostalis_cervicis] synonym: "iliocostalis cervicis" RELATED [Wikipedia:Iliocostalis] synonym: "cervicalis ascendens" RELATED [Wikipedia:Iliocostalis] synonym: "cervicalis ascendens muscle" RELATED [Wikipedia:Iliocostalis] is_a: UBERON:0002251 {source="FMA"} ! iliocostalis xref: FMA:22704 ! iliocostalis cervicis relationship: innervated_by UBERON:0006839 {source="dbpedia"} ! posterior ramus of spinal nerve xref: SCTID:244851000 ! Entire splenius cervicis muscle [Term] id: UBERON:0001400 name: iliocostalis thoracis muscle def: "The iliocostalis dorsi (musculus accessorius; iliocostalis thoracis) arises by flattened tendons from the upper borders of the angles of the lower six ribs medial to the tendons of insertion of the iliocostalis lumborum; these become muscular, and are inserted into the upper borders of the angles of the upper six ribs and into the back of the transverse process of the seventh cervical vertebra." [Wikipedia:Iliocostalis#Iliocostalis_thoracis] synonym: "musculus accessorius" RELATED [Wikipedia:Iliocostalis] synonym: "iliocostalis thoracis" RELATED [Wikipedia:Iliocostalis] synonym: "iliocostalis thoracis muscle" RELATED [Wikipedia:Iliocostalis] xref: FMA:22703 ! Iliocostalis thoracis xref: MA:0002320 ! iliocostalis thoracis is_a: UBERON:0002251 ! iliocostalis xref: SCTID:244856005 ! Entire iliocostalis thoracis muscle [Term] id: UBERON:0011207 name: iliocostalis lumborum def: "The iliocostalis lumborum (iliocostalis muscle; sacrolumbalis muscle) is inserted, by six or seven flattened tendons, into the inferior borders of the angles of the lower six or seven ribs." [Wikipedia:Iliocostalis#Iliocostalis_lumborum] synonym: "sacrolumbalis" RELATED [Wikipedia:Iliocostalis] synonym: "sacrolumbalis muscle" RELATED [Wikipedia:Iliocostalis] is_a: UBERON:0002251 {source="FMA"} ! iliocostalis xref: FMA:22702 ! iliocostalis lumborum xref: SCTID:244855009 ! Entire iliocostalis lumborum muscle [Term] id: UBERON:0002252 name: splenius def: "." [Wikipedia:Splenius] synonym: "splenius muscle" EXACT [] comment: Muscle of neck in NA subset: uberon_slim xref: FMA:77180 ! Splenius xref: MA:0002382 ! splenius xref: ncithesaurus:Splenius ! Splenius is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column xref: UMLS:C1185944 [Term] id: UBERON:0002254 name: thyroglossal duct def: "The thyroglossal duct is an embryological anatomical structure forming an open connection between the initial area of development of the thyroid gland and its final position. The thyroid gland starts developing in the oropharynx in the fetus and descends to its final position taking a path through the tongue, hyoid bone and neck muscles. The connection between its original position and its final position is the thyroglossal duct. This duct normally atrophies and closes off before birth but can remain open in some people. [WP,unvetted]." [Wikipedia:Thyroglossal_duct] synonym: "ductus thyreoglossus" EXACT [Wikipedia:Thyroglossal_duct] comment: FMA treats this as vestigial subset: uberon_slim xref: FMA:77274 ! Thyroglossal duct xref: VHOG:0000746 ! thyroglossal duct xref: MA:0000130 ! thyroglossal duct xref: ncithesaurus:Thyroglossal_Duct ! Thyroglossal Duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fd/Illu08_thyroid.jpg/200px-Illu08_thyroid.jpg xref: EMAPA:17070 ! thyroglossal duct of thyroid of gland of foregut xref: EMAPA:18833 ! thyroglossal duct of thyroid of gland of gut is_a: UBERON:0000058 ! duct is_a: UBERON:0006590 ! vestigial embryonic structure relationship: part_of UBERON:0002046 ! thyroid gland xref: SCTID:308822005 ! Entire thyroglossal duct synonym: "ductus thyroglossalis" RELATED LATIN [Wikipedia:Thyroglossal_duct] xref: http://upload.wikimedia.org/wikipedia/commons/f/fd/Illu08_thyroid.jpg property_value: external_definition "An embryonic duct extending between the thyroid primordium and the posterior tongue. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000746", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/thyroglossal+duct", source="http://bgee.unil.ch/"} property_value: homology_notes "A duct, called the thyroglossal duct in mammals, is considered to be characteristic of thyroid development. The thyroglossal duct, degenerating in many species during late development, marks the way the thyroid primordium relocates during embryonic development from the pharynx to its position deep in the cervical mesenchyme. We cannot exclude that the duct of the endostyle and the thyroglossal duct may have evolved independently, but as they both represent a more or less persistent connection of the organ to the pharynx, it is likely that they are homologous structures.[well established][VHOG]" xsd:string {external_class="VHOG:0000746", ontology="VHOG", source="DOI:10.1007/s00427-004-0450-0 Kluge B\, Renault N\, Rohr KB\, Anatomical and molecular reinvestigation of lamprey endostyle development provides new insight into thyroid gland evolution. Development genes and evolution (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231104 [Term] id: UBERON:0009954 ! vomeronasal system name: vomeronasal system def: "a vertebrate nasal chemosensory system that is responsible for detecting intraspecific pheromonal cues as well as environmental odorants" [] comment: Editor note: check relationship to olfactory system. Evolution: The morphological components of the VNS are found only in tetrapods, but the genetic components of the system have been found in teleost fish, in addition to tetrapods. In tetrapods, the VNS was thought to be the olfactory system for detecting pheromones, while the main olfactory system detected general odorants (Scalia and Winans 1975). However, experimental evidence suggests that there is not such a clear functional distinction (Restrepo et al. 2004; Baxi, Dorries, and Eisthen 2006; Spehr et al. 2006; Kelliher 2007). Sea lampreys produce unique bile acids which act as pheromones both in migration and mate finding (Li, Sorensen, and Gallaher 1995; Li et al. 2002; Siefkes and Li 2004). However, bile acids in teleost fish are known to require components of the main olfactory signal transduction pathway (Hansen et al. 2003), and interruption of the VNS signal transduction pathway had no effect on bile acid olfactory response (Hansen et al. 2003)[Grus - EVOLUTION OF THE VOMERONASAL SYSTEM VIEWED THROUGH SYSTEM-SPECIFIC GENES] is_a: UBERON:0001032 ! sensory system relationship: capable_of GO:0043695 {source="Wikipedia"} ! detection of pheromone relationship: part_of UBERON:0005725 ! olfactory system relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda [Term] id: UBERON:0002255 name: vomeronasal organ def: "The vomeronasal organ (VNO), or Jacobson's organ, is an auxiliary olfactory sense organ that is found in many animals. It was discovered by Ludwig Jacobson in 1813. During embryological development, it forms from the nasal (olfactory) placode, at the anterior edge of the neural plate. It is a chemoreceptor organ which is completely separated from the nasal cavity the majority of the time, being enclosed in a separate bony or cartilaginous capsule which opens into the base of the nasal cavity. It is a tubular crescent shape and split into two pairs, separated by the nasal septum. It is the first processing stage of the accessory olfactory system, after which chemical stimuli go to the accessory olfactory bulb, then to targets in the amygdala and hypothalamus. The vomeronasal organ is mainly used to detect pheromones, chemical messengers that carry information between individuals of the same species, hence is sometimes referred to as the 'sixth sense. ' The VNO has two separate types of neuronal receptors, V1R and V2R, which are seven-transmembrane receptors that are coupled to G proteins. The receptors are distinct from each other and form the large family of receptors in the main olfactory system. Evidence shows that the VNO responds to nonvolatile cues which stimulate the receptor neurons. Information is then transferred to the accessory olfactory bulb as well as other centres of the brain such as the anterior part of the hypothalamus. Its presence in many animals has been widely studied and the importance of the vomeronasal system to the role of reproduction and social behavior (through influence on anterior hypothalamus) has been shown in many studies. Its presence and functionality in humans is widely controversial, though most studies agree the organ regresses during fetal development. [WP,unvetted]." [Wikipedia:Vomeronasal_organ, Wikipedia:Vomeronasal_organ] comment: Taxon notes: Generally formed only in tetrapods; lungfish have rudimentary VN organs; true VN organs are not normally found in recent fishes, birds, aquatic reptiles, aquatic mammals (Bertmar 1980). Humans: Its presence in many animals has been widely studied and the importance of the vomeronasal system to the role of reproduction and social behavior (through influence on anterior hypothalamus) has been shown in many studies. Its presence and functionality in humans was controversial, though most studies agree the organ regresses during fetal development. Many genes essential for VNO function in animals (such as TRPC2) are non-functional in humans (Liman ER. Use it or lose it: molecular evolution of sensory signaling in primates. Pflugers Arch. 2006;453(2):125-31.) subset: uberon_slim synonym: "Jacobson's organ" EXACT [XAO:0000272] synonym: "organ of Jacobsen" RELATED [] synonym: "organum vomeronasale" EXACT [BTO:0002608] synonym: "organon vomeronasale" EXACT [] xref: EHDAA:7865 ! vomeronasal organ xref: FMA:77280 ! Vomeronasal organ xref: GAID:354 ! vomeronasal organ xref: VHOG:0000665 ! vomeronasal organ xref: MA:0000289 ! vomeronasal organ xref: BTO:0002608 ! vomeronasal organ xref: EFO:0001934 ! vomeronasal organ xref: EHDAA2:0002211 ! vomeronasal organ xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Gray51.png/200px-Gray51.png xref: XAO:0000272 ! Jacobson's organ xref: EMAPA:17612 ! vomeronasal organ xref: MESH:A04.531.591.940 ! vomeronasal organ is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0000004 ! olfactory apparatus relationship: part_of UBERON:0009954 ! vomeronasal system relationship: capable_of GO:0043695 {source="Wikipedia"} ! detection of pheromone relationship: develops_from UBERON:0003050 {source="Wikipedia"} ! olfactory placode relationship: has_developmental_contribution_from UBERON:0009714 {source="EHDAA2-abduced"} ! intermaxillary process relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda xref: AAO:0000997 ! vomeronasal organ xref: SCTID:361346007 ! Entire vomeronasal organ subset: organ_slim synonym: "organum vomeronasale" RELATED LATIN [Wikipedia:Vomeronasal_organ] xref: http://upload.wikimedia.org/wikipedia/commons/8/84/Gray51.png synonym: "VNO" RELATED [VHOG:0000665] property_value: external_definition "An organ thought to supplement the olfactory system in receiving pheromonic communication. The sensory part of the organ is in two long, thin sacs, situated on either side of the nasal septum at its base. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000665", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/vomeronasal+organ", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) the vomeronasal organ is known only in some tetrapods. It is absent in most turtles, crocodiles, birds, some bats, and aquatic mammals. In amphibians, it is in a recessed area off the main nasal cavity. (...) In mammals possesing this organ, it is an isolated area of olfactory membrane within the nasal cavity that is usually connected to the mouth via the nasopalatine duct (reference 1); The opinions concerning the presence and functioning of the vomeronasal organ in humans are controversial. The vomeronasal cavities appear early in human foetuses. (...) Historical examination of the nasal septum revealed the presence of vomeronasal cavities in approximately 70% of adults. In contrast to the situation in other mammals, the organ is not supported by a rigid tube of bone or cartilage (reference 2); (...) the best evidence for the homology of the human VNO to that of other primates (and of mammals in general) is ontogenetic in nature, based on a common embryonic origin from a thickening (vomeronasal primordium) on the medial aspect of each olfactory pit (reference 3); (...) suggesting that lungfish possess a region homologous to the accessory olfactory bulb of tetrapods. Based on these results, it seems appropriate to refer to the recess epithelium as a primordium of the vomeronasal organ (reference 4). [debated][VHOG]" xsd:string {external_class="VHOG:0000665", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.669 (ref.1)\, PMID:9866877 Doving KB\, Trotier D\, Review: Structure and function of the vomeronasal organ. The Journal of Experimental Biology (1998) (ref.2)\, DOI:10.1046/j.1469-7580.2001.19810077.x Smith TD\, Siegel MI\, Bonar CJ\, Bhatnagar KP\, Mooney MP\, Burrows AM\, Smith MA\, Maico LM\, The existence of the vomeronasal organ in postnatal chimpanzees and evidence for its homology with that of humans. J Anat (2001) (ref.3) \, DOI:10.1002/ar.22415 Nakamuta S\, Nakamuta N\, Taniguchi K\, Taniguchi K\, Histological and ultrastructural characteristics of the primordial vomeronasal organ in lungfish. Anat Rec (Hoboken) (2012) (ref.4)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003367 ! epithelium of vomeronasal organ name: epithelium of vomeronasal organ def: "An epithelium that is part of a vomeronasal organ [Automatically generated definition]." [OBOL:automatic] synonym: "Jacobson's organ epithelial tissue" EXACT [OBOL:automatic] synonym: "Jacobson's organ epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of Jacobson's organ" EXACT [OBOL:automatic] synonym: "epithelial tissue of vomeronasal organ" EXACT [OBOL:automatic] synonym: "epithelium of Jacobson's organ" EXACT [OBOL:automatic] synonym: "vomeronasal organ epithelial tissue" EXACT [OBOL:automatic] synonym: "vomeronasal organ epithelium" EXACT [OBOL:automatic] synonym: "vomeronasal organ sensory epithelium" EXACT [MA:0001328] synonym: "vomeronasal epithelium" EXACT [EHDAA2:0004102] xref: EMAPA:18444 ! epithelium of vomeronasal organ xref: MA:0001328 ! vomeronasal organ sensory epithelium xref: EHDAA2:0004102 ! vomeronasal epithelium is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0001997 {source="EHDAA2"} ! olfactory epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002255 ! vomeronasal organ [Term] id: UBERON:0007822 name: vomeronasal cartilage def: "The vomeronasal cartilage (or Jacobson's cartilage) is a narrow strip of cartilage, low on the medial wall of the nasal cavity. It lies between the cartilaginous nasal septum and the vomer. The cartilage lies below, but is not connected to, the rudimentary vomeronasal organ of Jacobson[WP]." [Wikipedia:Vomeronasal_cartilage] synonym: "Huschke's cartilage" EXACT [FMA:59514] synonym: "Jacobson's cartilage" EXACT [FMA:59514] xref: FMA:59514 ! Vomeronasal cartilage is_a: UBERON:0001823 {source="FMA"} ! nasal cartilage xref: SCTID:368123006 ! Entire vomeronasal cartilage synonym: "cartilago vomeronasalis" RELATED LATIN [Wikipedia:Vomeronasal_cartilage] xref: http://upload.wikimedia.org/wikipedia/commons/8/84/Gray51.png [Term] id: UBERON:0003421 name: mesenchyme of vomeronasal organ def: "Mesenchyme that is part of a vomeronasal organ [Automatically generated definition]." [OBOL:automatic] synonym: "Jacobson's organ mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of Jacobson's organ" EXACT [OBOL:automatic] synonym: "vomeronasal organ mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18445 ! mesenchyme of vomeronasal organ xref: EHDAA2:0004103 ! vomeronasal mesenchyme synonym: "vomeronasal mesenchyme" EXACT [EHDAA2:0004103] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002255 ! vomeronasal organ relationship: develops_from UBERON:0009204 {source="EHDAA2"} ! medial nasal process mesenchyme [Term] id: UBERON:0009121 name: vomeronasal nerve def: "Nerve carrying fibers from the vomeronasal organ to the accessory olfactory bulb[AAO]. originates in the olfactory epithelial cells of Jacobson's organ, and that passes through the submucous tissue of the nasal septum and the cribriform plate of the ethmoid bone to the olfactory bulb[BTO]." [AAO:DSM, BTO:0001351, ISBN10:0471888893] comment: in the human this disappears before birth is_a: UBERON:0001785 {source="NIF_GrossAnatomy"} ! cranial nerve relationship: overlaps UBERON:0003367 {source="Wikipedia"} ! epithelium of vomeronasal organ relationship: overlaps UBERON:0002264 ! olfactory bulb relationship: develops_from UBERON:0003050 {source="ISBN10:0471888893"} ! olfactory placode xref: AAO:0010608 ! vomeronasal nerve xref: BTO:0001351 ! vomeronasal nerve xref: NIF_GrossAnatomy:nlx_anat_1005018 ! Vomeronasal nerve property_value: external_definition "Nerve carrying fibers from the vomeronasal organ to the accessory olfactory bulb.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010608", date_retrieved="2012-06-20", source="AAO:DSM"} [Term] id: UBERON:0002318 name: white matter of spinal cord def: "the regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites." [MP:0008027] comment: This class was created automatically from a combination of ontologies synonym: "spinal cord white matter" EXACT [] synonym: "spinal cord white matter of neuraxis" EXACT [OBOL:automatic] synonym: "spinal cord white substance" EXACT [OBOL:automatic] synonym: "white matter of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "white substance of spinal cord" EXACT [OBOL:automatic] xref: FMA:83945 ! White matter of spinal cord xref: MA:0000910 ! spinal cord white matter is_a: UBERON:0002316 ! white matter of neuraxis intersection_of: UBERON:0002316 ! white matter of neuraxis intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord xref: ncithesaurus:White_Matter_of_the_Spinal_Cord ! White Matter of the Spinal Cord xref: SCTID:279436006 ! Entire spinal cord white matter xref: UMLS:C0458457 [Term] id: UBERON:0006127 ! funiculus of spinal cord name: funiculus of spinal cord synonym: "spinal cord funiculus" EXACT [FMA:77460] synonym: "white column of spinal cord" EXACT [FMA:77460] xref: FMA:77460 ! funiculus of spinal cord is_a: UBERON:0006080 ! segment of white matter of spinal cord is_a: UBERON:0006133 ! funiculus relationship: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0002258 ! dorsal funiculus name: dorsal funiculus def: "The portion of the medulla spinalis which lies between the posterolateral sulcus and the posterior median sulcus is named the posterior funiculus. This area includes the dorsal columns (also called the posterior columns) which contains the fasciculus gracilis and, higher in the body, the fasciculus cuneatus, which are separated by a partition of glial cells. Histologically, these two fasciculi are on other sides of the dorsal intermediate sulcus. [WP,unvetted]." [Wikipedia:Dorsal_funiculus] subset: uberon_slim subset: vertebrate_core synonym: "dorsal funiculus of spinal cord" EXACT [] synonym: "posterior funiculus of spinal cord" EXACT [] synonym: "posterior funiculus" EXACT [] synonym: "dorsal white column of spinal cord" EXACT [FMA:77461] synonym: "posterior white column of spinal cord" EXACT [FMA:77461] synonym: "funiculus dorsalis" EXACT [ZFA:0000501] xref: FMA:77461 ! Dorsal funiculus of spinal cord xref: TAO:0000501 ! dorsal funiculus xref: ZFA:0000501 ! dorsal funiculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Medulla_spinalis_-_Section_-_English.svg/200px-Medulla_spinalis_-_Section_-_English.svg.png is_a: UBERON:0006127 ! funiculus of spinal cord synonym: "funiculus posterior medullae spinalis" EXACT LATIN [FMA:TA, FMA:77461] xref: SCTID:362432005 ! Entire dorsal funiculus relationship: in_lateral_side_of UBERON:0002318 {source="FMA-abduced-lr"} ! white matter of spinal cord [Term] id: UBERON:0002179 ! lateral funiculus name: lateral funiculus def: "The most lateral of the bundles of the anterior nerve roots is generally taken as a dividing line that separates the antero-lateral region into two parts, viz. , an anterior funiculus, between the anterior median fissure and the most lateral of the anterior nerve roots; and a lateral funiculus, between the exit of these roots and the postero-lateral sulcus. [WP,unvetted]." [Wikipedia:Lateral_funiculus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "lateral funiculus of spinal cord" EXACT [] synonym: "lateral white column of spinal cord" EXACT [FMA:74000] xref: FMA:74000 ! Lateral funiculus of spinal cord xref: TAO:0000533 ! lateral funiculus xref: ZFA:0000533 ! lateral funiculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Medulla_spinalis_-_Section_-_English.svg/200px-Medulla_spinalis_-_Section_-_English.svg.png is_a: UBERON:0006127 ! funiculus of spinal cord xref: SCTID:362434006 ! Entire lateral funiculus synonym: "funiculus lateralis medullae spinalis" RELATED LATIN [Wikipedia:Lateral_funiculus] xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Medulla_spinalis_-_Section_-_English.svg [Term] id: UBERON:0002180 ! ventral funiculus name: ventral funiculus def: "The most lateral of the bundles of the anterior nerve roots is generally taken as a dividing line that separates the antero-lateral region into two parts, viz. , an anterior funiculus, between the anterior median fissure and the most lateral of the anterior nerve roots; and a lateral funiculus, between the exit of these roots and the postero-lateral sulcus. [WP,unvetted]." [Wikipedia:Ventral_funiculus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "anterior funiculus" EXACT [] synonym: "anterior funiculus of spinal cord" EXACT [] synonym: "ventral funiculus of spinal cord" EXACT [] synonym: "anterior white column of spinal cord" EXACT [FMA:74003] synonym: "ventral white column of spinal cord" EXACT [FMA:74003] xref: FMA:74003 ! Ventral funiculus of spinal cord xref: TAO:0000605 ! ventral funiculus xref: ZFA:0000605 ! ventral funiculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Medulla_spinalis_-_Section_-_English.svg/200px-Medulla_spinalis_-_Section_-_English.svg.png is_a: UBERON:0006127 ! funiculus of spinal cord synonym: "funiculus anterior medullae spinalis" EXACT LATIN [FMA:TA, FMA:74003] xref: SCTID:362429007 ! Entire ventral funiculus relationship: in_lateral_side_of UBERON:0002318 {source="FMA-abduced-lr"} ! white matter of spinal cord [Term] id: UBERON:0006080 ! segment of white matter of spinal cord name: segment of white matter of spinal cord xref: FMA:258174 ! segment of white matter of spinal cord is_a: UBERON:0002318 ! white matter of spinal cord [Term] id: UBERON:0002256 name: dorsal horn of spinal cord def: "the pronounced, dorsolaterally oriented ridge of grey matter in each lateral half of the spinal cord[MP]. the dorsal (more towards the back) grey matter of the spinal cord. It receives several types of sensory information from the body, including light touch, proprioception, and vibration. This information is sent from receptors of the skin, bones, and joints through sensory neurons whose cell bodies lie in the dorsal root ganglion[WP]. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input[GO]." [Wikipedia:Posterior_horn_of_spinal_cord, GO:0021516, MP:0006282, https://sourceforge.net/tracker/?group_id=36855&atid=440764] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "dorsal grey column of spinal cord" EXACT [] synonym: "dorsal spinal cord" BROAD [] synonym: "dorsal region of spinal cord" BROAD [] synonym: "dorsal region of mature spinal cord" BROAD [] synonym: "posterior horn of spinal cord" EXACT [Wikipedia:Posterior_horn_of_spinal_cord] synonym: "posterior grey column of spinal cord" EXACT [] synonym: "spinal cord dorsal horn" EXACT [] synonym: "spinal cord dorsal horns" RELATED PLURAL [] synonym: "dorsal gray column of spinal cord" EXACT [FMA:256530] synonym: "dorsal gray matter of spinal cord" EXACT [FMA:256530] synonym: "posterior gray column of spinal cord" EXACT [FMA:256530] synonym: "posterior gray horn of spinal cord" EXACT [FMA:256530] synonym: "dorsal horn spinal cord" EXACT [ZFA:0000649] synonym: "cornu dorsale" EXACT [ZFA:0000649] synonym: "dorsal horn" BROAD [ZFA:0000649] synonym: "dorsal gray horn" EXACT [NIF_GrossAnatomy:birnlex_2667] synonym: "spinal cord posterior horn" EXACT [NIF_GrossAnatomy:birnlex_2667] synonym: "dorsal grey horn" BROAD [EMAPA:18574] synonym: "cornu posterius medullae spinalis" EXACT LATIN [Wikipedia:Posterior_horn_of_spinal_cord] xref: FMA:256530 ! Dorsal gray column of spinal cord xref: VHOG:0001287 ! spinal cord dorsal horn xref: MA:0001119 ! spinal cord dorsal horn xref: NIF_GrossAnatomy:birnlex_2667 ! Spinal cord dorsal horn xref: ZFA:0000649 ! dorsal horn spinal cord xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Medulla_spinalis_-_Section_-_English.svg/200px-Medulla_spinalis_-_Section_-_English.svg.png xref: EMAPA:18574 ! dorsal grey horn xref: BM:SpC-DH ! dorsal horn is_a: UBERON:0001948 ! regional part of spinal cord relationship: part_of UBERON:0002315 ! gray matter of spinal cord relationship: has_function_in GO:0019230 {source="GO"} ! proprioception relationship: in_lateral_side_of UBERON:0002315 {source="FMA-abduced-lr"} ! gray matter of spinal cord relationship: has_part CL:0000101 ! sensory neuron xref: ncithesaurus:Dorsal_Horn_of_the_Spinal_Cord ! Dorsal Horn of the Spinal Cord xref: SCTID:180961004 ! Entire dorsal spinal cord xref: TAO:0000649 ! dorsal horn spinal cord xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Medulla_spinalis_-_Section_-_English.svg xref: UMLS:C0228575 [Term] id: UBERON:0002257 name: ventral horn of spinal cord def: "the ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]." [GO:0021517, MP:0005112, Wikipedia:Anterior_horn_of_spinal_cord, https://sourceforge.net/tracker/?group_id=36855&atid=440764] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "anterior grey column of spinal cord" EXACT [] synonym: "spinal cord ventral horn" EXACT [] synonym: "ventral spinal cord" EXACT [] synonym: "ventral region of spinal cord" EXACT [] synonym: "ventral grey column of spinal cord" EXACT [] synonym: "ventral gray column of spinal cord" EXACT [FMA:256541] synonym: "anterior gray column of spinal cord" EXACT [FMA:256541] synonym: "anterior gray horn of spinal cord" EXACT [FMA:256541] synonym: "ventral gray matter of spinal cord" EXACT [FMA:256541] synonym: "ventral horn spinal cord" EXACT [ZFA:0000702] synonym: "anterior horn" EXACT [NIF_GrossAnatomy:birnlex_2668] synonym: "spinal cord anterior horn" EXACT [NIF_GrossAnatomy:birnlex_2668] synonym: "ventral grey horn" EXACT [NIF_GrossAnatomy:birnlex_2668] synonym: "ventral horns spinal cord" RELATED PLURAL [VHOG:0001288] synonym: "anterior column" RELATED [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "anterior column of the spinal cord" RELATED [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "anterior horn (spinal cord)" RELATED [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "cornu anterius medullae spinalis" RELATED LATIN [Wikipedia:Anterior_horn_of_spinal_cord] xref: VHOG:0001288 ! spinal cord ventral horn xref: MA:0001134 ! spinal cord ventral horn xref: NIF_GrossAnatomy:birnlex_2668 ! Spinal cord ventral horn xref: FMA:256541 ! Ventral gray column of spinal cord xref: ZFA:0000702 ! ventral horn spinal cord xref: EMAPA:18575 ! ventral grey horn is_a: UBERON:0001948 ! regional part of spinal cord relationship: part_of UBERON:0002315 ! gray matter of spinal cord relationship: has_part CL:0000100 ! motor neuron relationship: in_lateral_side_of UBERON:0002315 {source="FMA-abduced-lr"} ! gray matter of spinal cord xref: ncithesaurus:Ventral_Horn_of_the_Spinal_Cord ! Ventral Horn of the Spinal Cord xref: SCTID:279443000 ! Entire anterior gray horn of spinal cord xref: TAO:0000702 ! ventral horn spinal cord xref: UMLS:C0228590 property_value: external_definition "The anterior horn of the spinal cord (or anterior cornu, or anterior column, or ventral horn) is the ventral (front) grey matter section of the spinal cord. The anterior horn contains motor neurons that affect the axial muscles while the posterior horn receives information regarding touch and sensation. The anterior horn is where the cell bodies of alpha motorneurons are located[Wikipedia:Anterior_horn_of_spinal_cord]." xsd:string {source="Wikipedia:Anterior_horn_of_spinal_cord"} [Term] id: UBERON:0005373 ! spinal cord dorsal column name: spinal cord dorsal column def: "area of white matter in the dorsomedial side of the spinal cord. It is made up of the fasciculus gracilis and fasciculus cuneatus and itself is part of the dorsal funiculus. It is part of an ascending pathway that is important for well-localized fine touch and conscious proprioception called the posterior column-medial lemniscus pathway[WP]. The dorsal portion of the gray substance of the spinal cord, in transverse section seen as a horn[TFD]. The dorsal column is a part of the spinal cord which is responsible for transporting sensory input from the body to the cerebral cortex. This part of the spinal cord is key in perceiving fine touch, such as that used to distinguish textures, along with vibration. The dorsal column also contributes to the body's system of proprioception, used to orient the body in space and to coordinate muscle movements, given information about the body's position." [Wikipedia:Posterior_column] comment: TODO - relationship with dorsal horn? synonym: "dorsal column" EXACT [] synonym: "dorsal column of spinal cord" EXACT [] synonym: "posterior column" EXACT [Wikipedia:Posterior_column] synonym: "spinal cord posterior column" EXACT [] xref: MA:0002749 ! spinal cord dorsal column xref: EV:0100317 ! dorsal column is_a: UBERON:0002318 ! white matter of spinal cord relationship: part_of UBERON:0002258 ! dorsal funiculus relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception xref: ncithesaurus:Posterior_Column ! Posterior Column xref: VHOG:0001623 ! spinal cord dorsal column property_value: external_definition "The dorsolateral ridge of gray matter in each lateral half of the spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001623", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/posterior+column+of+spinal+cord", source="http://bgee.unil.ch/"} xref: UMLS:C0458459 [Term] id: UBERON:0006079 ! subdivision of spinal cord dorsal column name: subdivision of spinal cord dorsal column subset: non_informative synonym: "segment of dorsal funiculus of spinal cord" RELATED [FMA:258190] xref: FMA:258190 ! Segment of dorsal funiculus of spinal cord is_a: UBERON:0006080 ! segment of white matter of spinal cord relationship: part_of UBERON:0005373 ! spinal cord dorsal column [Term] id: UBERON:0005839 name: thoracic spinal cord dorsal column synonym: "thoracic spinal cord posterior column" EXACT [NIF_GrossAnatomy:birnlex_1442] synonym: "thoracic segment of dorsal funiculus of spinal cord" EXACT [FMA:258178] synonym: "dorsal funiculus of thoracic segment of spinal cord" EXACT [FMA:258178] synonym: "dorsal white column of thoracic segment of spinal cord" EXACT [FMA:258178] xref: NIF_GrossAnatomy:birnlex_1442 ! Thoracic spinal cord dorsal column xref: FMA:258178 ! thoracic segment of dorsal funiculus of spinal cord intersection_of: UBERON:0006079 ! subdivision of spinal cord dorsal column intersection_of: part_of UBERON:0003038 ! thoracic spinal cord def: "A subdivision of spinal cord dorsal column that is part of a thoracic spinal cord." [OBOL:automatic] [Term] id: UBERON:0005840 name: sacral spinal cord dorsal column synonym: "sacral spinal cord posterior column" EXACT [NIF_GrossAnatomy:birnlex_1514] synonym: "sacral subsegment of dorsal funiculus of spinal cord" EXACT [FMA:258198] xref: NIF_GrossAnatomy:birnlex_1514 ! Sacral spinal cord dorsal column xref: FMA:258198 ! sacral subsegment of dorsal funiculus of spinal cord intersection_of: UBERON:0006079 ! subdivision of spinal cord dorsal column intersection_of: part_of UBERON:0005843 ! sacral spinal cord def: "A subdivision of spinal cord dorsal column that is part of a sacral spinal cord." [OBOL:automatic] [Term] id: UBERON:0005841 name: cervical spinal cord dorsal column synonym: "cervical spinal cord posterior column" EXACT [NIF_GrossAnatomy:birnlex_736] synonym: "cervical segment of dorsal funiculus of spinal cord" EXACT [FMA:258176] synonym: "dorsal funiculus of cervical segment of spinal cord" EXACT [FMA:258176] synonym: "dorsal white column of cervical segment of spinal cord" EXACT [FMA:258176] xref: NIF_GrossAnatomy:birnlex_736 ! Cervical spinal cord dorsal column xref: FMA:258176 ! cervical segment of dorsal funiculus of spinal cord intersection_of: UBERON:0006079 ! subdivision of spinal cord dorsal column intersection_of: part_of UBERON:0002726 ! cervical spinal cord def: "A subdivision of spinal cord dorsal column that is part of a cervical spinal cord." [OBOL:automatic] [Term] id: UBERON:0005842 name: lumbar spinal cord dorsal column synonym: "lumbar spinal cord posterior column" EXACT [NIF_GrossAnatomy:birnlex_834] synonym: "lumbar segment of dorsal funiculus of spinal cord" EXACT [FMA:258180] synonym: "dorsal funiculus of lumbar segment of spinal cord" EXACT [FMA:258180] synonym: "dorsal white column of lumbar segment of spinal cord" EXACT [FMA:258180] synonym: "lumbar segment of gracile fasciculus of spinal cord" EXACT [FMA:258180] xref: NIF_GrossAnatomy:birnlex_834 ! Lumbar spinal cord dorsal column xref: FMA:258180 ! lumbar segment of dorsal funiculus of spinal cord intersection_of: UBERON:0006079 ! subdivision of spinal cord dorsal column intersection_of: part_of UBERON:0002792 ! lumbar spinal cord def: "A subdivision of spinal cord dorsal column that is part of a lumbar spinal cord." [OBOL:automatic] [Term] id: UBERON:0005374 ! spinal cord lateral column name: spinal cord lateral column comment: TODO - check relationship between column and funiculus. Also check white vs grey matter. See ventral column. Note also ZFA term 'lateral column' is part of reticular formation synonym: "lateral column" RELATED [] xref: MA:0002750 ! spinal cord lateral column xref: EV:0100322 ! lateral column xref: ZFA:0000531 ! lateral column is_a: UBERON:0002318 {source="MA"} ! white matter of spinal cord relationship: part_of UBERON:0002179 {notes="checkme"} ! lateral funiculus xref: TAO:0000531 ! lateral column xref: VHOG:0001621 ! spinal cord lateral column [Term] id: UBERON:0004676 name: spinal cord lateral horn def: "a triangular field that is a lateralward projection of the postero-lateral part of the anterior column[WP, modified by cjm]." [Wikipedia:Lateral_horn_of_spinal_cord] comment: todo - check relationship to spinal cord lateral column. in FMA funiculus=white and horn=grep synonym: "spinal cord lateral horn" EXACT [NIF_GrossAnatomy:birnlex_2666] synonym: "intermediate gray column of spinal cord" EXACT [FMA:256536] synonym: "intermediate grey column of spinal cord" EXACT [FMA:256536] synonym: "lateral gray matter of spinal cord" EXACT [FMA:256536] synonym: "lateral horn of spinal cord" EXACT [FMA:256536] synonym: "lateral gray column of spinal cord" EXACT [FMA:256536] synonym: "spinal cord intermediate horn" EXACT [NIF_GrossAnatomy:birnlex_2666] synonym: "lateral gray horn" EXACT [NIF_GrossAnatomy:birnlex_2666] xref: FMA:256536 ! lateral gray column of spinal cord xref: NIF_GrossAnatomy:birnlex_2666 ! Spinal cord lateral horn is_a: UBERON:0002315 {source="FMA"} ! gray matter of spinal cord xref: ncithesaurus:Lateral_Horn_of_the_Spinal_Cord ! Lateral Horn of the Spinal Cord synonym: "cornu laterale medullae spinalis" RELATED LATIN [Wikipedia:Lateral_horn_of_spinal_cord] xref: http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray675.png relationship: in_lateral_side_of UBERON:0002315 {source="FMA-abduced-lr"} ! gray matter of spinal cord xref: UMLS:C0228582 [Term] id: UBERON:0006078 ! subdivision of spinal cord lateral column name: subdivision of spinal cord lateral column subset: non_informative is_a: UBERON:0006080 ! segment of white matter of spinal cord relationship: part_of UBERON:0005374 ! spinal cord lateral column [Term] id: UBERON:0005847 name: thoracic spinal cord lateral column xref: NIF_GrossAnatomy:birnlex_1439 ! Thoracic spinal cord lateral column intersection_of: UBERON:0006078 ! subdivision of spinal cord lateral column intersection_of: part_of UBERON:0003038 ! thoracic spinal cord def: "A subdivision of spinal cord lateral column that is part of a thoracic spinal cord." [OBOL:automatic] [Term] id: UBERON:0005848 name: sacral spinal cord lateral column xref: NIF_GrossAnatomy:birnlex_1587 ! Sacral spinal cord lateral column intersection_of: UBERON:0006078 ! subdivision of spinal cord lateral column intersection_of: part_of UBERON:0005843 ! sacral spinal cord def: "A subdivision of spinal cord lateral column that is part of a sacral spinal cord." [OBOL:automatic] [Term] id: UBERON:0005849 name: cervical spinal cord lateral column xref: NIF_GrossAnatomy:birnlex_729 ! Cervical spinal cord lateral column intersection_of: UBERON:0006078 ! subdivision of spinal cord lateral column intersection_of: part_of UBERON:0002726 ! cervical spinal cord def: "A subdivision of spinal cord lateral column that is part of a cervical spinal cord." [OBOL:automatic] [Term] id: UBERON:0005850 name: lumbar spinal cord lateral column xref: NIF_GrossAnatomy:birnlex_828 ! Lumbar spinal cord lateral column intersection_of: UBERON:0006078 ! subdivision of spinal cord lateral column intersection_of: part_of UBERON:0002792 ! lumbar spinal cord def: "A subdivision of spinal cord lateral column that is part of a lumbar spinal cord." [OBOL:automatic] [Term] id: UBERON:0005375 ! spinal cord ventral column name: spinal cord ventral column comment: in MA, this is a subclass of white matter, but in WP/Gray's, the anterior column is a synonym of the grey matter section. is this the same as funiculus? See lateral column. synonym: "ventral column" EXACT [] synonym: "anterior column" EXACT [] synonym: "spinal cord anterior column" EXACT [] xref: MA:0002751 ! spinal cord ventral column xref: EV:0100326 ! ventral column is_a: UBERON:0002318 ! white matter of spinal cord relationship: part_of UBERON:0002180 ! ventral funiculus xref: VHOG:0001622 ! spinal cord ventral column property_value: external_definition "The ventral ridge of gray matter in each half of the spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001622", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/anterior+column+of+spinal+cord", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005852 name: thoracic spinal cord ventral column xref: NIF_GrossAnatomy:birnlex_1448 ! Thoracic spinal cord ventral column is_a: UBERON:0002318 ! white matter of spinal cord relationship: part_of UBERON:0005375 ! spinal cord ventral column relationship: part_of UBERON:0003038 ! thoracic spinal cord [Term] id: UBERON:0005853 name: sacral spinal cord ventral column xref: NIF_GrossAnatomy:birnlex_1520 ! Sacral spinal cord ventral column is_a: UBERON:0002318 ! white matter of spinal cord relationship: part_of UBERON:0005375 ! spinal cord ventral column relationship: part_of UBERON:0005843 ! sacral spinal cord [Term] id: UBERON:0005854 name: cervical spinal cord ventral column synonym: "cervical spinal cord anterior column" EXACT [NIF_GrossAnatomy:birnlex_1660] xref: NIF_GrossAnatomy:birnlex_1660 ! Cervical spinal cord ventral column is_a: UBERON:0002318 ! white matter of spinal cord relationship: part_of UBERON:0005375 ! spinal cord ventral column relationship: part_of UBERON:0002726 ! cervical spinal cord [Term] id: UBERON:0005855 name: lumbar spinal cord ventral column xref: NIF_GrossAnatomy:birnlex_840 ! Lumbar spinal cord ventral column is_a: UBERON:0002318 ! white matter of spinal cord relationship: part_of UBERON:0005375 ! spinal cord ventral column relationship: part_of UBERON:0002792 ! lumbar spinal cord [Term] id: UBERON:0005821 ! gracile fasciculus name: gracile fasciculus alt_id: UBERON:0004168 def: "a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb[GO]. The fasciculus gracilis (tract of Goll) is a bundle of axon fibres in the dorsomedial spinal cord that carries information about fine touch, vibrations, and conscious proprioception from the lower part of the body to the brain stem. It is part of the posterior column of the spinal cord, which also contains the fasciculus cuneatus, which carries the same information from the upper part of the body. This tract and its continuation in the brain stem is often referred to as the posterior column-medial lemniscus pathway. The fasciculus gracilis is wedge-shaped on transverse section and lies next the posterior median septum, its base being at the surface of the medulla spinalis, and its apex directed toward the posterior gray commissure. It increases in size from below upward, and consists of long thin fibers that are derived from the posterior nerve roots, and ascend as far as the medulla oblongata, where they end in the nucleus gracilis. The tract of Goll was named after Swiss neuroanatomist Friedrich Goll[WP]." [Wikipedia:Gracile_fasciculus, GO:0021958] comment: distinction between axon tract and fasicule is unclear, we create is_a parentage to both synonym: "gracile column" RELATED [Wikipedia:Gracile_fasciculus] synonym: "gracile tract" RELATED [Wikipedia:Gracile_fasciculus] synonym: "fasciculus gracilis" EXACT [FMA:258416] synonym: "gracile fascicle" EXACT [FMA:258416] synonym: "tract of Goll" EXACT [GO:0021958] synonym: "gracilis tract" EXACT [GO:0021958] xref: FMA:258416 ! gracile fasciculus xref: BM:Me-GF ! gracile fasciculus is_a: UBERON:0001018 ! axon tract is_a: UBERON:0001019 ! fascicle relationship: part_of UBERON:0002316 ! white matter of neuraxis relationship: has_function_in GO:0019230 {source="GO"} ! proprioception xref: ncithesaurus:Tract_of_Goll ! Tract of Goll xref: SCTID:369079001 ! Entire fasciculus gracilis synonym: "f. gracilis medullae spinalis" RELATED LATIN [Wikipedia:Gracile_fasciculus] xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg xref: UMLS:C0228522 [Term] id: UBERON:0002653 name: gracile fasciculus of medulla synonym: "column of goll" EXACT [] synonym: "fasciculus of goll" EXACT [] synonym: "goll's tract" EXACT [FMA:72624] synonym: "gracile fascicle of medulla" EXACT [FMA:72624] synonym: "medulla segment of fasciculus gracilis" EXACT [FMA:72624] synonym: "medulla segment of gracile fasciculus" EXACT [FMA:72624] synonym: "tract of gall" EXACT [] synonym: "gracile fascicle (gall)" EXACT [NIF_GrossAnatomy:birnlex_1282] xref: FMA:72624 ! Gracile fasciculus of medulla xref: NIF_GrossAnatomy:birnlex_1282 ! Gracile fasciculus of medulla intersection_of: UBERON:0005821 ! gracile fasciculus intersection_of: part_of UBERON:0001896 ! medulla oblongata def: "A gracile fasciculus that is part of a medulla oblongata." [OBOL:automatic] [Term] id: UBERON:0005826 name: gracile fasciculus of spinal cord comment: editor note: check ontology structure, isa parentage to fasciculus of spinal cord should be inferred synonym: "gracile fascicle of spinal cord" EXACT [FMA:73938] synonym: "spinal cord segment of fasciculus gracilis" EXACT [FMA:73938] synonym: "spinal cord segment of gracile fasciculus" EXACT [FMA:73938] xref: FMA:73938 ! gracile fasciculus of spinal cord is_a: UBERON:0005837 ! fasciculus of spinal cord intersection_of: UBERON:0005821 ! gracile fasciculus intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0005373 ! spinal cord dorsal column def: "A gracile fasciculus that is part of a spinal cord." [OBOL:automatic] relationship: part_of UBERON:0002318 {is_inferred="true", source="reference_0000032"} ! white matter of spinal cord [Term] id: UBERON:0005832 ! cuneate fasciculus name: cuneate fasciculus alt_id: UBERON:0004169 comment: we assign the synonym 'Burdachs tract' to the subclass synonym: "cuneate column" RELATED [Wikipedia:Cuneate_fasciculus] synonym: "cuneate tract" RELATED [Wikipedia:Cuneate_fasciculus] synonym: "fasciculus cuneatus" RELATED [Wikipedia:Cuneate_fasciculus] synonym: "fasciculus cuneus" RELATED [Wikipedia:Cuneate_fasciculus] synonym: "cuneatus tract" EXACT [GO:0021959] xref: Wikipedia:Cuneate_fasciculus ! cuneate fasciculus xref: BM:Me-CF ! cuneate fasciculus is_a: UBERON:0001018 ! axon tract [Term] id: UBERON:0002642 name: cuneate fasciculus of medulla comment: TODO - change definition to be the *whole* of the CF in the MO. isa parentage to fasciculus of brain should be inferred xref: FMA:72623 ! Cuneate fasciculus of medulla xref: NIF_GrossAnatomy:birnlex_1242 ! Cuneate fasciculus of medulla is_a: UBERON:0005838 ! fasciculus of brain intersection_of: UBERON:0005832 ! cuneate fasciculus intersection_of: part_of UBERON:0001896 ! medulla oblongata def: "A cuneate fasciculus that is part of a medulla oblongata." [OBOL:automatic] [Term] id: UBERON:0005835 name: cuneate fasciculus of spinal cord def: "The fasciculus cuneatus (tract of Burdach, named for Karl Friedrich Burdach) is a bundle of nerves in the spinal cord which primarily transmits information from the arms. It is part of the posterior column-medial lemniscus pathway." [Wikipedia:Cuneate_fasciculus, GO:0021959] comment: editor note: check ontology structure, isa parentage to fasciculus of spinal cord should be inferred. TODO - change definition to be the *whole* of the CF in the SC synonym: "burdach's tract" EXACT [FMA:73941] synonym: "cuneate fascicle of spinal cord" EXACT [FMA:73941] synonym: "cuneate fasciculus" BROAD [FMA:73941] synonym: "tract of Burdach" EXACT [GO:0021959] xref: FMA:73941 ! cuneate fasciculus of spinal cord is_a: UBERON:0005837 ! fasciculus of spinal cord intersection_of: UBERON:0005832 ! cuneate fasciculus intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0005373 ! spinal cord dorsal column synonym: "fasciculus cuneatus" EXACT LATIN [FMA:TA, FMA:73941] xref: ncithesaurus:Tract_of_Burdach ! Tract of Burdach xref: SCTID:314792006 ! Entire fasciculus cuneatus synonym: "fasciculus cuneatus medullae spinalis" RELATED LATIN [Wikipedia:Cuneate_fasciculus] xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg xref: UMLS:C0228578 [Term] id: UBERON:0009623 name: spinal nerve root def: "The paired bundles of nerve fibers entering and leaving the spinal cord at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots efferent, comprising the axons of spinal motor and autonomic preganglionic neurons. There are, however, some exceptions to this afferent/efferent rule." [MESH:A08.800.800.720.725] comment: ZFA has part_of to spinal cord but this causes spatial disjointness violations (CNS/PNS) synonym: "spinal neural root" EXACT [FMA:14060] synonym: "root of spinal nerve" EXACT [FMA:14060] intersection_of: UBERON:0002211 ! nerve root intersection_of: part_of UBERON:0001780 ! spinal nerve is_a: UBERON:0002211 {source="FMA"} ! nerve root relationship: part_of UBERON:0001780 {source="FMA"} ! spinal nerve xref: GAID:717 ! spinal nerve root xref: MESH:A08.800.800.720.725 ! spinal nerve root xref: ZFA:0005578 ! spinal nerve root xref: FMA:14060 ! root of spinal nerve xref: ncithesaurus:Spinal_Nerve_Root ! Spinal Nerve Root xref: SCTID:362436008 ! Entire dorsal spinal nerve root (also: UBERON:0002261 'dorsal root of spinal cord') xref: UMLS:C0037940 [Term] id: UBERON:0002260 name: ventral root of spinal cord def: "The efferent motor root of a spinal nerve. At its distal end, the ventral root joins with the dorsal root to form a mixed spinal nerve." [Wikipedia:Anterior_root_of_spinal_nerve] comment: FMA:77516 xref is a 'general anatomical term'. We xref both to ensure equivalence. subset: uberon_slim subset: vertebrate_core synonym: "anterior nerve root" RELATED [Wikipedia:Anterior_root_of_spinal_nerve] synonym: "anterior root" RELATED [Wikipedia:Anterior_root_of_spinal_nerve] synonym: "ventral root" BROAD [NIF_GrossAnatomy:nlx_anat_20090209] xref: FMA:77516 ! Ventral root xref: FMA:5979 ! Anterior root of spinal nerve xref: NIF_GrossAnatomy:nlx_anat_20090209 ! Ventral root xref: TAO:0000705 ! ventral root xref: ZFA:0000705 ! ventral root xref: BTO:0000865 ! anterior spinal root synonym: "anterior spinal root" EXACT [BTO:0000865] xref: ncithesaurus:Ventral_Nerve_Root ! Ventral Nerve Root xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/Spinal_nerve.svg/200px-Spinal_nerve.svg.png is_a: UBERON:0009623 {source="FMA", different_relation_from="ZFA"} ! spinal nerve root synonym: "radix anterior nervi spinalis" RELATED LATIN [Wikipedia:Anterior_root_of_spinal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg synonym: "anterior root of spinal nerve" RELATED [FMA:5979] synonym: "motor root of spinal nerve" RELATED [FMA:5979] synonym: "radix anterior (nervus spinalis)" RELATED [FMA:5979] synonym: "radix motoria (nervus spinalis)" RELATED [FMA:5979] synonym: "ventral root of spinal nerve" RELATED [FMA:5979] synonym: "ventral spinal nerve root" RELATED [FMA:5979] xref: UMLS:C0205956 [Term] id: UBERON:0002261 name: dorsal root of spinal cord def: "In anatomy and neurology, the dorsal root (or posterior root) is the afferent sensory root of a spinal nerve. At the distal end of the dorsal root is the dorsal root ganglion, which contains the neuron cell bodies of the nerve fibres conveyed by the root. If the dorsal root of a spinal nerve were severed it would lead to numbness in certain areas of the body. The lateral division of the dorsal root contains lightly myelinated and unmyelinated axons of small diameter. These transmit pain and temperature sensation from the body. These fibers cross through the anterior white commissure to form the Anterior lateral system in the lateral funiculus. The medial division of the dorsal root contains myelinated axons of larger diameter. These transmit information of discriminative touch, pressure, vibration, and conscious proprioception originating from spinal levels C2 through S5. These fibers are pushed in towards the posterior medial sulcus to form the fasciculus gracilis and the fasciculus cuneatus. [WP,unvetted]." [Wikipedia:Posterior_root_of_spinal_nerve] comment: FMA xref is 'general anatomical term'. We xref both to ensure equivalence. subset: uberon_slim subset: vertebrate_core synonym: "dorsal root" EXACT [ZFA:0000652] synonym: "radix dorsalis" EXACT [ZFA:0000652] synonym: "posterior root of spinal nerve" EXACT [Wikipedia:Posterior_root_of_spinal_nerve] synonym: "dorsal root of spinal nerve" EXACT [FMA:5980] synonym: "dorsal spinal nerve root" EXACT [FMA:5980] synonym: "radix posterior (nervus spinalis)" EXACT [FMA:5980] synonym: "radix sensoria (nervus spinalis)" EXACT [FMA:5980] synonym: "sensory root of spinal nerve" EXACT [FMA:5980] xref: FMA:5980 ! posterior root of spinal nerve xref: NIF_GrossAnatomy:nlx_anat_20090208 ! Dorsal root xref: TAO:0000652 ! dorsal root xref: ZFA:0000652 ! dorsal root xref: NIF_GrossAnatomy:nlx_anat_20090208 ! Dorsal root xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/Spinal_nerve.svg/200px-Spinal_nerve.svg.png xref: BTO:0000360 ! posterior spinal root is_a: UBERON:0009623 {source="FMA"} ! spinal nerve root relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception xref: ncithesaurus:Dorsal_Root_of_the_Spinal_Nerve ! Dorsal Root of the Spinal Nerve xref: SCTID:362436008 ! Entire dorsal spinal nerve root (also: UBERON:0009623 'spinal nerve root') synonym: "radix posterior" RELATED LATIN [Wikipedia:Posterior_root_of_spinal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg xref: UMLS:C0205955 [Term] id: UBERON:0009630 name: root of thoracic nerve synonym: "thoracic nerve root" EXACT [FMA:14064] synonym: "thoracic neural root" EXACT [FMA:14064] synonym: "nerve root part of thoracic spinal cord" EXACT [NIF:NIF] intersection_of: UBERON:0009623 ! spinal nerve root intersection_of: part_of UBERON:0003726 ! thoracic nerve xref: FMA:14064 ! root of thoracic nerve xref: NIF_GrossAnatomy:birnlex_836 ! Nerve root part of thoracic spinal cord def: "A spinal nerve root that is part of a thoracic nerve." [OBOL:automatic] [Term] id: UBERON:0009631 name: root of lumbar spinal nerve synonym: "lumbar spinal nerve root" EXACT [FMA:16421] synonym: "lumbar spinal neural root" EXACT [FMA:16421] synonym: "nerve root part of lumbar spinal cord" EXACT [NIF:NIF] intersection_of: UBERON:0009623 ! spinal nerve root intersection_of: part_of UBERON:0009624 ! lumbar nerve xref: FMA:16421 ! root of lumbar spinal nerve xref: NIF_GrossAnatomy:birnlex_1613 ! Nerve root part of lumbar spinal cord xref: ncithesaurus:Lumbar_Spinal_Nerve_Root ! Lumbar Spinal Nerve Root xref: SCTID:180968005 ! Entire lumbar spinal nerve root def: "A spinal nerve root that is part of a lumbar nerve." [OBOL:automatic] xref: UMLS:C0581666 [Term] id: UBERON:0009632 name: root of cervical nerve synonym: "cervical neural root" EXACT [FMA:16422] synonym: "cervical spinal root" EXACT [FMA:16422] synonym: "root of cervical spinal nerve" EXACT [FMA:16422] synonym: "nerve root part of cervical spinal cord" EXACT [NIF:NIF] is_a: UBERON:0009623 ! spinal nerve root relationship: part_of UBERON:0000962 ! cervical nerve xref: FMA:16422 ! root of cervical nerve xref: NIF_GrossAnatomy:birnlex_955 ! Nerve root part of cervical spinal cord xref: ncithesaurus:Cervical_Spinal_Nerve_Root ! Cervical Spinal Nerve Root xref: SCTID:180966009 ! Entire cervical spinal nerve root xref: UMLS:C0581631 [Term] id: UBERON:0009633 name: root of sacral nerve synonym: "root of sacral spinal nerve" EXACT [FMA:18028] synonym: "sacral neural root" EXACT [FMA:18028] synonym: "nerve root part of sacral spinal cord" EXACT [NIF:NIF] intersection_of: UBERON:0009623 ! spinal nerve root intersection_of: part_of UBERON:0009625 ! sacral nerve xref: FMA:18028 ! root of sacral nerve xref: NIF_GrossAnatomy:birnlex_1518 ! Nerve root part of sacral spinal cord xref: ncithesaurus:Sacral_Spinal_Nerve_Root ! Sacral Spinal Nerve Root xref: SCTID:244454000 ! Entire sacral spinal nerve root def: "A spinal nerve root that is part of a sacral nerve." [OBOL:automatic] xref: UMLS:C0581672 [Term] id: UBERON:0009634 name: root of coccygeal nerve synonym: "coccygeal neural root" EXACT [FMA:18131] synonym: "coccygeal spinal nerve root" EXACT [FMA:18131] synonym: "root of coccygeal spinal nerve" EXACT [FMA:18131] intersection_of: UBERON:0009623 ! spinal nerve root intersection_of: part_of UBERON:0009629 ! coccygeal nerve xref: FMA:18131 ! root of coccygeal nerve def: "A spinal nerve root that is part of a coccygeal nerve." [OBOL:automatic] [Term] id: UBERON:0002262 name: celiac ganglion def: "The celiac ganglia are two large irregularly shaped masses of nerve tissue in the upper abdomen. Part of the sympathetic subdivision of the autonomic nervous system (ANS), the two celiac ganglia are the largest ganglia in the ANS, and they innervate most of the digestive tract. They have the appearance of lymph glands and are placed on either side of the midline in front of the crura of the diaphragm, close to the suprarenal glands (also called adrenal glands). The ganglion on the right side is placed behind the inferior vena cava. They are sometimes referred to as the semilunar ganglia or the solar ganglia. [WP,unvetted]." [Wikipedia:Celiac_ganglia] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "coeliac ganglion" RELATED [] xref: EHDAA:8946 ! coeliac ganglion xref: FMA:77570 ! Celiac ganglion xref: MA:0001158 ! celiac ganglion xref: ncithesaurus:Coeliac_Ganglion ! Celiac Ganglion xref: EHDAA2:0000266 ! coeliac ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/63/Gray848.png/200px-Gray848.png xref: EMAPA:19321 ! coeliac is_a: UBERON:0003964 ! prevertebral ganglion xref: SCTID:362492008 ! Entire celiac ganglion xref: http://upload.wikimedia.org/wikipedia/commons/6/63/Gray848.png xref: UMLS:C0007571 [Term] id: UBERON:0002263 name: lentiform nucleus def: "The lentiform nucleus or lenticular nucleus comprises the putamen and the globus pallidus within the basal ganglia. It is a large, cone-shaped mass of gray matter just lateral to the internal capsule. [WP,unvetted]. The part of the corpus striatum somewhat resembling a biconvex lens, divided into an external, larger, lateral part (putamen) and an internal, smaller, lighter colored medial part (globus pallidus), which is in turn subdivided into a smaller, medial, and a larger, lateral part by the medial medullary lamina[BTO]." [Wikipedia:Lentiform_nucleus, BTO:0002250] comment: AO notes: the EMAPA class is unclear. Editor notes: TODO - add parts subset: uberon_slim synonym: "nucleus lentiformis" EXACT [BTO:0002250] synonym: "nucleus lenticularis" EXACT [BTO:0002250] synonym: "lenticular nucleus" RELATED [BTO:0002250] xref: FMA:77615 ! Lentiform nucleus xref: MA:0000896 ! lentiform nucleus xref: EMAPA:18208 ! lentiform nucleus xref: EMAPA:19147 ! lenticular nucleus xref: BTO:0002250 ! nucleus lentiformis xref: ncithesaurus:Lenticular_Nucleus ! Lenticular Nucleus xref: OpenCyc:Mx4rvvyH2ZwpEbGdrcN5Y29ycA ! lentiform nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fc/Gray741.png/200px-Gray741.png xref: EV:0100186 ! lentiform nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0000369 ! corpus striatum relationship: part_of UBERON:0005403 ! ventral striatum relationship: has_part UBERON:0001874 ! putamen relationship: has_part UBERON:0001875 ! globus pallidus xref: SCTID:279319002 ! Entire lentiform nucleus synonym: "nucleus lentiformis" RELATED LATIN [Wikipedia:Lentiform_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/f/fc/Gray741.png xref: UMLS:C0162342 [Term] id: UBERON:0002265 ! olfactory tract name: olfactory tract def: "White matter tract that contains projections from the olfactory bulb to the olfactory cortex (Maryann Martone)" [NIF_GrossAnatomy:birnlex_1663, Wikipedia:Olfactory_tract, ISBN10:0471888893] comment: AO notes: sources differ as to whether this is part of the bulb (BTO), or cortex (MA). We represent this as the connection between the two, and is thus entirely part of neither, yet overlaps both. Note that the NIF class has been retired subset: uberon_slim synonym: "olfactory peduncle" RELATED [BTO:0003647] synonym: "tractus olfactorius" RELATED [BTO:0003647] synonym: "tractus olfactorius" RELATED LATIN [Wikipedia:Olfactory_tract] xref: FMA:77626 ! Olfactory tract xref: MA:0000975 ! olfactory tract xref: NIF_GrossAnatomy:birnlex_1663 ! Olfactory tract xref: ncithesaurus:Olfactory_Tract ! Olfactory Tract xref: BTO:0003647 ! olfactory tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray732.png/200px-Gray732.png xref: SCTID:362356008 ! Entire olfactory tract intersection_of: UBERON:0007702 ! tract of brain intersection_of: overlaps UBERON:0002894 ! olfactory cortex intersection_of: overlaps UBERON:0002264 ! olfactory bulb relationship: part_of UBERON:0001893 ! telencephalon property_value: external_definition "Tract of brain which is continuous with olfactory bulb and the cerebral cortex.[FMA]" xsd:string {source="FMA"} property_value: external_definition "A nervelike, white band composed primarily of nerve fibres originating from the mitral cells and tufted cells of the olfactory bulb but also containing the scattered cells of the anterior olfactory nucleus[BTO:0003647]." xsd:string {source="BTO:0003647"} property_value: external_definition "The olfactory tract is a bundle of axons connecting the mitral and tufted cells of the olfactory bulb to several target regions in the brain, including piriform cortex, amygdala, and entorhinal cortex. It is a narrow white band, triangular on coronal section, the apex being directed upward. It lies in the olfactory sulcus on the inferior surface of the frontal lobe, and divides posteriorly into two striæ, a medial olfactory stria and a lateral olfactory stria.[Wikipedia]." xsd:string {source="Wikipedia:Olfactory_tract"} property_value: external_definition "White matter tract that contains projections from the olfactory bulb to the olfactory cortex (Maryann Martone)" xsd:string {source="NIF_GrossAnatomy:birnlex_1663", notes="deprecated class"} xref: UMLS:C0162435 [Term] id: UBERON:0001888 name: lateral olfactory tract def: "The lateral olfactory stria is directed across the lateral part of the anterior perforated substance and then bends abruptly medialward toward the uncus of the hippocampal gyrus." [Wikipedia:Lateral_olfactory_stria] comment: Editor notes: We follow neurolex and use 'tract' rather than 'stria' as the primary label. We make this a subtype of olfactory tract. Currently this groups teleost and mammalian structures by the same name, but this may be a false grouping. For example, in zebrafish, the difference between medial and lateral depends on the region of telencephalon (dorsal or ventral). Taxon notes: In mammals the fibers of the dorsal lateral olfactory tract either pass under the accessory olfactory formation, or they penetrate through it separating the internal granule cells from the output cells.[PMID:7437895] subset: uberon_slim subset: vertebrate_core synonym: "LOT" RELATED ABBREVIATION [] synonym: "lateral olfactory stria" RELATED [FMA:61971] synonym: "tractus olfactorius lateralis" EXACT LATIN [ZFA:0000229] synonym: "stria olfactoria lateralis" RELATED LATIN [Wikipedia:Lateral_olfactory_stria] xref: FMA:61971 ! Lateral olfactory stria xref: NIF_GrossAnatomy:birnlex_1559 ! Lateral olfactory stria xref: TAO:0000229 ! lateral olfactory tract xref: ZFA:0000229 ! lateral olfactory tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray732.png/200px-Gray732.png xref: EV:0100175 ! lateral olfactory stria xref: BM:Tel-LOT ! lateral olfactory tract xref: SCTID:369107001 ! Entire lateral olfactory striae is_a: UBERON:0002265 ! olfactory tract xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray732.png property_value: external_definition "Telencephalic white matter which extends between the olfactory bulb and the ipsilateral dorsal telencephalon and carries secondary olfactory fibers. From Neuroanatomy of the Zebrafish Brain[ZFA:0000229]." xsd:string {source="ZFA:0000229"} [Term] id: UBERON:0001883 name: olfactory tubercle def: "a multi-sensory processing center in the olfactory cortex that plays a role in reward behaviors. The OT is a composite structure that receives direct input from the olfactory bulb and contains the morphological and histochemical characteristics of the ventral pallidum and the striatum of the forebrain (Heimer & Wilson 1975)." [Wikipedia:Anterior_perforated_substance] comment: AO notes: NIF has separate classes for exact syns in FMA subset: uberon_slim synonym: "anterior perforated area" EXACT [FMA:61891] synonym: "anterior perforated space" EXACT [FMA:61891] synonym: "olfactory area (Mai)" EXACT [FMA:61891] synonym: "anterior perforated substance" EXACT [FMA:61891] xref: FMA:61891 ! Anterior perforated substance xref: MA:0000976 ! olfactory tubercle xref: NIF_GrossAnatomy:birnlex_1096 ! Anterior perforated substance xref: NIF_GrossAnatomy:nlx_anat_1005037 ! Olfactory tubercle xref: BTO:0001869 ! olfactory tubercle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray732.png/200px-Gray732.png xref: EV:0100177 ! olfactory tubercle xref: ABA:OT ! Olfactory tubercle xref: BM:Tel-OLT ! olfactory tubercle xref: EHDAA2:0004701 ! olfactory tubercle is_a: UBERON:0005813 {source="FMA"} ! tubercle is_a: UBERON:0002020 {source="EHDAA2"} ! gray matter of neuraxis relationship: part_of UBERON:0002894 {source="MA", source="Wikipedia", source="EHDAA2-inferred"} ! olfactory cortex relationship: part_of UBERON:0005401 {source="BTO"} ! cerebral grey matter relationship: part_of UBERON:0001869 {source="FMA"} ! cerebral hemisphere relationship: spatially_disjoint_from UBERON:0001882 {source="ABA"} ! nucleus accumbens synonym: "tuberculum olfactorium" EXACT LATIN [FMA:TA, FMA:61891] xref: SCTID:369108006 ! Entire anterior perforated substance synonym: "substantia perforata anterior" RELATED LATIN [Wikipedia:Anterior_perforated_substance] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray732.png xref: VHOG:0001625 ! olfactory tubercle property_value: external_definition "Subdivision of telencephalon which is a region on the ventro-medial aspect of the telencephalon penetrated by numerous blood vessels. It is bounded by the optic tract posteriorly and the olfactory trigone anteriorly[FMA:61891, Wikipedia:Anterior_perforated_substance]." xsd:string {source="FMA:61891"} [Term] id: UBERON:0002893 name: nucleus of lateral olfactory tract comment: part of amygdala in FMA but this leads to inconsistency when combined with ABA partitions synonym: "lateral olfactory tract nucleus" EXACT [FMA:61865] synonym: "nucleus of the lateral olfactory tract (ganser)" EXACT [NIF_GrossAnatomy:birnlex_2702] xref: FMA:61865 ! Nucleus of lateral olfactory tract xref: NIF_GrossAnatomy:birnlex_2702 ! Nucleus of lateral olfactory tract xref: ABA:NLOT ! Nucleus of the lateral olfactory tract xref: BM:Tel-NLOT ! nucleus of lateral olfactory tract is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002264 {source="ABA"} ! olfactory bulb relationship: spatially_disjoint_from UBERON:0004069 {source="ABA"} ! accessory olfactory bulb relationship: spatially_disjoint_from UBERON:0002266 {source="ABA"} ! anterior olfactory nucleus relationship: spatially_disjoint_from UBERON:0002590 {source="ABA"} ! prepyriform area [Term] id: UBERON:0002266 name: anterior olfactory nucleus def: "The anterior olfactory nucleus (AON; also called the anterior olfactory cortex) is a portion of the forebrain of vertebrates. [WP,unvetted]." [Wikipedia:Anterior_olfactory_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "retrobulbar nucleus [a8]" EXACT [] synonym: "anterior olfactory cortex" RELATED [BTO:0003649] synonym: "AON" RELATED [BTO:0003649] xref: FMA:77628 ! Anterior olfactory nucleus xref: MA:0000968 ! anterior olfactory nucleus xref: NIF_GrossAnatomy:birnlex_1085 ! Anterior olfactory nucleus xref: ncithesaurus:Anterior_Olfactory_Nucleus ! Anterior Olfactory Nucleus xref: BTO:0003649 ! anterior olfactory nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Human_brainstem_anterior_view_2_description.JPG/200px-Human_brainstem_anterior_view_2_description.JPG xref: EV:0100174 ! anterior olfactory nucleus xref: ABA:AON ! Anterior olfactory nucleus xref: BM:Tel-OAN ! anterior olfactory nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002264 {source="ABA"} ! olfactory bulb relationship: part_of UBERON:0002894 ! olfactory cortex relationship: spatially_disjoint_from UBERON:0004069 {source="ABA"} ! accessory olfactory bulb relationship: spatially_disjoint_from UBERON:0002893 {source="ABA"} ! nucleus of lateral olfactory tract relationship: spatially_disjoint_from UBERON:0002590 {source="ABA"} ! prepyriform area synonym: "nucleus retrobulbaris [a8]" EXACT LATIN [FMA:TA, FMA:77628] synonym: "nucleus olfactorius anterior" RELATED LATIN [Wikipedia:Anterior_olfactory_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Human_brainstem_anterior_view_2_description.JPG xref: UMLS:C0175225 [Term] id: UBERON:0002267 name: laterodorsal tegmental nucleus def: "The laterodorsal tegmental nucleus (or lateroposterior tegmental nucleus) is a nucleus situated in the brainstem, spanning the midbrain tegmentum and the pontine tegmentum. [WP,unvetted]." [Wikipedia:Laterodorsal_tegmental_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lateroposterior tegmental nucleus" EXACT [] xref: FMA:77654 ! Laterodorsal tegmental nucleus xref: MA:0001016 ! laterodorsal tegmental nucleus xref: BTO:0004016 ! laterodorsal tegmental nucleus xref: ABA:LDT ! Laterodorsal tegmental nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0000988 ! pons relationship: spatially_disjoint_from UBERON:0003004 {source="ABA"} ! median raphe nucleus relationship: spatially_disjoint_from UBERON:0002148 {source="ABA"} ! locus ceruleus relationship: spatially_disjoint_from UBERON:0002047 {source="ABA"} ! pontine raphe nucleus relationship: spatially_disjoint_from UBERON:0002587 {source="ABA"} ! nucleus subceruleus synonym: "nucleus tegmentalis posterolateralis" EXACT LATIN [FMA:TA, FMA:77654] synonym: "nucleus tegmentalis posterolateralis" RELATED LATIN [Wikipedia:Laterodorsal_tegmental_nucleus] [Term] id: UBERON:0002269 name: pupillary membrane def: "The pupillary membrane in mammals exists in the fetus as a source of blood supply for the lens. It normally atrophies from the time of birth to the age of four to eight weeks." [Wikipedia:Persistent_pupillary_membrane] comment: This class was created automatically from a combination of ontologies xref: FMA:77663 ! Pupillary membrane xref: MA:0001293 ! pupillary membrane is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0000922 ! embryo relationship: located_in UBERON:0001771 {source="MA-modified"} ! pupil relationship: part_of UBERON:0001769 ! iris [Term] id: UBERON:0002271 name: periventricular zone of hypothalamus comment: This class was created automatically from a combination of ontologies synonym: "hypothalamus periventricular zone" EXACT [] xref: FMA:77682 ! Periventricular zone of hypothalamus xref: VHOG:0000623 ! hypothalamus periventricular zone xref: MA:0000846 ! hypothalamus periventricular zone xref: ABA:PVZ ! Periventricular zone is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001898 ! hypothalamus [Term] id: UBERON:0002272 name: medial zone of hypothalamus comment: This class was created automatically from a combination of ontologies synonym: "hypothalamus medial zone" EXACT [] xref: FMA:77683 ! Medial zone of hypothalamus xref: MA:0000837 ! hypothalamus medial zone xref: ABA:MEZ ! Hypothalamic medial zone is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001898 ! hypothalamus [Term] id: UBERON:0002273 name: lateral zone of hypothalamus comment: This class was created automatically from a combination of ontologies synonym: "hypothalamus lateral zone" EXACT [] xref: FMA:77684 ! Lateral zone of hypothalamus xref: MA:0000833 ! hypothalamus lateral zone xref: ABA:LZ ! Hypothalamic lateral zone is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001898 ! hypothalamus [Term] id: UBERON:0002274 name: perifornical nucleus comment: This class was created automatically from a combination of ontologies xref: FMA:77688 ! Perifornical nucleus xref: MA:0000836 ! perifornical nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002273 ! lateral zone of hypothalamus [Term] id: UBERON:0010267 name: obsolete inferior reticular formation def: "." [GO:0021728] is_obsolete: true [Term] id: UBERON:0010268 name: obsolete superior reticular formation def: "." [GO:0021729] is_obsolete: true [Term] id: UBERON:0002275 name: reticular formation comment: note that this class denotes the generic structure, and not a specific one such as medullary or pontine reticular formation. subset: uberon_slim xref: FMA:77719 ! Reticular formation xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9b/Gray701.png/200px-Gray701.png xref: MESH:A08.186.211.132.772 ! reticular formation is_a: UBERON:0000073 ! regional part of nervous system xref: SCTID:361552007 ! Entire reticular formation [Term] id: UBERON:0002559 ! medullary reticular formation name: medullary reticular formation def: "The reticular formation is a series of brain nuclei located in the medulla oblongata" [GO:0021723] comment: note that ZFA:0000421 is part of the the medulla oblongata, so it is placed here, rather than with the generic term subset: vertebrate_core synonym: "bulbar reticular formation" EXACT [FMA:72241] synonym: "reticular formation of medulla" EXACT [FMA:72241] synonym: "rhombencephalic reticular formation" EXACT [GO:0021723] synonym: "medullary reticular nucleus" EXACT [MA:0001049] synonym: "reticular formation" BROAD [ZFA:0000421] synonym: "bulb reticular formation" EXACT [OBOL:automatic] synonym: "medulla oblongata reticular formation" EXACT [OBOL:automatic] synonym: "medulla oblonmgata reticular formation" EXACT [OBOL:automatic] synonym: "metepencephalon reticular formation" EXACT [OBOL:automatic] synonym: "reticular formation of bulb" EXACT [OBOL:automatic] synonym: "reticular formation of medulla oblongata" EXACT [OBOL:automatic] synonym: "reticular formation of medulla oblonmgata" EXACT [OBOL:automatic] synonym: "reticular formation of metepencephalon" EXACT [OBOL:automatic] xref: FMA:72241 ! Medullary reticular formation xref: NIF_GrossAnatomy:birnlex_1020 ! Medullary reticular formation xref: MA:0001049 ! medullary reticular nucleus xref: TAO:0000421 ! reticular formation xref: ZFA:0000421 ! reticular formation xref: GAID:588 ! reticular formation xref: ABA:MDRN ! Medullary reticular nucleus xref: BM:Me-MeRF ! medullary reticular formation is_a: UBERON:0002275 {source="FMA"} ! reticular formation relationship: part_of UBERON:0001896 {source="FMA"} ! medulla oblongata intersection_of: UBERON:0002275 ! reticular formation intersection_of: part_of UBERON:0001896 ! medulla oblongata relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus xref: SCTID:369059009 ! Entire reticular formation of medulla oblongata [Term] id: UBERON:0002573 name: pontine reticular formation def: "The reticular formation is a part of the brain that is involved in actions such as awaking/sleeping cycle, and filtering incoming stimuli to discriminate irrelevant background stimuli. It is essential for governing some of the basic functions of higher organisms, and is one of the phylogenetically oldest portions of the brain. [WP,unvetted]." [Wikipedia:Pontine_reticular_formation] subset: uberon_slim synonym: "reticular formation of pons" EXACT [FMA:68876] synonym: "pons of varolius reticular formation" EXACT [OBOL:automatic] synonym: "pons reticular formation" EXACT [OBOL:automatic] synonym: "reticular formation of pons of varolius" EXACT [OBOL:automatic] synonym: "pontine reticular nucleus" EXACT [ABA:PRNr] xref: FMA:68876 ! Pontine reticular formation xref: NIF_GrossAnatomy:birnlex_1050 ! Pontine reticular formation xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9b/Gray701.png/200px-Gray701.png xref: BM:Pons-PRF ! pontine reticular formation xref: ABA:PRNr ! Pontine reticular nucleus (also: UBERON:0007413 'nucleus of pontine reticular formation') is_a: UBERON:0002275 {source="FMA"} ! reticular formation intersection_of: UBERON:0002275 ! reticular formation intersection_of: part_of UBERON:0000988 ! pons relationship: part_of UBERON:0003023 {source="FMA"} ! pontine tegmentum xref: SCTID:362403007 ! Entire reticular formation of pons [Term] id: UBERON:0002639 ! midbrain reticular formation name: midbrain reticular formation synonym: "reticular formation of midbrain" EXACT [FMA:62406] synonym: "tegmental reticular formation" EXACT [FMA:62406] xref: FMA:62406 ! Midbrain reticular formation xref: NIF_GrossAnatomy:birnlex_1235 ! Midbrain reticular formation xref: BM:MB-MBRF ! midbrain reticular formation is_a: UBERON:0002275 ! reticular formation intersection_of: UBERON:0002275 ! reticular formation intersection_of: part_of UBERON:0001891 ! midbrain relationship: has_part UBERON:0002142 ! pedunculopontine tegmental nucleus relationship: part_of UBERON:0001943 ! midbrain tegmentum xref: SCTID:369234009 ! Entire reticular formation of midbrain def: "A reticular formation that is part of a midbrain." [OBOL:automatic] [Term] id: UBERON:0007415 name: nucleus of midbrain reticular formation synonym: "midbrain reticular formation nucleus" EXACT [FMA:62443] synonym: "midbrain reticular nucleus" EXACT [ABA:MRN] xref: FMA:62443 ! nucleus of midbrain reticular formation xref: ABA:MRN ! Midbrain reticular nucleus intersection_of: UBERON:0007414 ! nucleus of midbrain tegmentum intersection_of: part_of UBERON:0002639 ! midbrain reticular formation def: "A nucleus of midbrain tegmentum that is part of a midbrain reticular formation." [OBOL:automatic] [Term] id: UBERON:0009775 name: lateral medullary reticular complex synonym: "lateral group of medullary reticular formation" EXACT [FMA:72573] synonym: "lateral medullary reticular group" EXACT [FMA:72573] synonym: "lateral reticular formation of the medulla oblongata" EXACT [FMA:72573] is_a: UBERON:0007245 {source="FMA"} ! nuclear complex of neuraxis relationship: part_of UBERON:0002559 {source="FMA"} ! medullary reticular formation xref: FMA:72573 ! lateral medullary reticular complex [Term] id: UBERON:0002154 name: lateral reticular nucleus def: "The lateral reticular nucleus, of the funiculus, can be divided into three subnuclei, the parvocellular, magnocellular and the subtrigeminal. As is typical of the reticular formation, none of these are very distinct subnuclei, but rather blurred distinctions between cell types and location. The lateral reticular nucleus sends all of its projections to the cerebellum. The parvocellular portion of the LRN and the immediately adjacent magnocellular portion send most their projections to the vermis of the cerebellum. The rest of the magnocellular subnucleus sends its projections to the hemisphere regions of the cerebellum. The subtrigeminal nucleus sends its projections to the flocculonodular lobe. All of these efferent pathways are projected in an ipsilateral manner to the cerebellum, the most abundant of which are those to the vermis. This nucleus is also involved in the mediation of inspiration (in-breathing) with a part of the ventral r. nucleus. The afferent pathways to the LRN come from the spinal cord and higher brain structures. Most of the afferents come from the ipsilateral dorsal horn of the spinal cord and project exclusively to the parts of the LRN that do not receive input from the cortex. The spinal cord projections terminate mostly in the parvocellular region along with the adjacent magnocellular cells. This implies that most input from the spinal cord is relayed into the vermis. [WP,unvetted]." [Wikipedia:Lateral_reticular_nucleus] comment: Comment: note in ABA this is disjoint from MDR, but we relax this here to accomodate FMA subset: uberon_slim subset: vertebrate_core synonym: "lateral reticular nucleus (medulla)" EXACT [] xref: FMA:72574 ! Lateral reticular nucleus xref: MA:0001047 ! lateral reticular nucleus xref: TAO:0000535 ! lateral reticular nucleus xref: ZFA:0000535 ! lateral reticular nucleus xref: NIF_GrossAnatomy:nlx_anat_20081246 ! Lateral reticular nucleus xref: ABA:LRN ! Lateral reticular nucleus xref: BM:LR ! lateral reticular nucleus is_a: UBERON:0007635 {source="FMA"} ! nucleus of medulla oblongata relationship: part_of UBERON:0009775 {source="FMA"} ! lateral medullary reticular complex intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0009775 ! lateral medullary reticular complex relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus synonym: "nucleus reticularis lateralis medullae oblongatae" RELATED LATIN [Wikipedia:Lateral_reticular_nucleus] [Term] id: UBERON:0009776 ! intermediate reticular formation name: intermediate reticular formation def: "." [https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3413098&group_id=36855] xref: TAO:0000219 ! intermediate reticular formation is_a: UBERON:0007245 {source="UBERON:cjm"} ! nuclear complex of neuraxis relationship: part_of UBERON:0002559 {source="GOC:pr", source="brainspan.org"} ! medullary reticular formation xref: ZFA:0000219 ! intermediate reticular formation [Term] id: UBERON:0009777 name: intermediate reticular nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0009776 ! intermediate reticular formation xref: FMA:84336 ! intermediate reticular nucleus xref: ABA:IRN ! Intermediate reticular nucleus def: "A nucleus of brain that is part of a intermediate reticular formation." [OBOL:automatic] [Term] id: UBERON:0002277 name: spiral sulcus def: "A concavity in the floor of the cochlear duct, formed by either the overhanging vestibular lip (inner spiral sulcus) or the spiral prominence and the spiral organ (outer spiral sulcus)." [] synonym: "sulcus spiralis" EXACT [] xref: FMA:77744 ! Spiral sulcus xref: MA:0001195 ! spiral sulcus is_a: UBERON:0000093 ! sulcus relationship: part_of UBERON:0001855 {source="MA"} ! cochlear duct of membranous labyrinth [Term] id: UBERON:0008831 name: inner spiral sulcus def: "a concavity in the floor of the cochlear duct formed by the overhanging vestibular lip." [http://www.drugs.com/dict/inner-spiral-sulcus.html] is_a: UBERON:0002277 {source="FMA"} ! spiral sulcus synonym: "sulcus spiralis internus" EXACT [http://www.drugs.com/dict/inner-spiral-sulcus.html] synonym: "internal spiral sulcus" EXACT [MA:0001197] comment: part_of spiral sulcus in MA xref: FMA:77850 ! inner spiral sulcus xref: MA:0001197 ! internal spiral sulcus [Term] id: UBERON:0008832 name: outer spiral sulcus def: "a concavity in the outer wall of the cochlear duct between the spiral prominence and the spiral organ." [http://www.drugs.com/dict/outer-spiral-sulcus.html] is_a: UBERON:0002277 {source="FMA"} ! spiral sulcus synonym: "sulcus spiralis externus" EXACT [http://www.drugs.com/dict/outer-spiral-sulcus.html] comment: part_of spiral sulcus in MA xref: FMA:77851 ! outer spiral sulcus xref: MA:0001196 ! external spiral sulcus synonym: "external spiral sulcus" EXACT [MA:0001196] [Term] id: UBERON:0002279 name: vestibular aqueduct def: "At the hinder part of the medial wall of the vestibule is the orifice of the vestibular aqueduct, which extends to the posterior surface of the petrous portion of the temporal bone. It transmits a small vein, and contains a tubular prolongation of the membranous labyrinth, the ductus endolymphaticus, which ends in a cul-de-sac between the layers of the dura mater within the cranial cavity. [WP,unvetted]." [Wikipedia:Vestibular_aqueduct] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:77821 ! Vestibular aqueduct xref: GAID:885 ! vestibular aqueduct xref: MA:0001186 ! vestibular aqueduct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray921.png/200px-Gray921.png xref: MESH:A09.246.631.909.957 ! vestibular aqueduct is_a: UBERON:0005744 ! cranial conduit relationship: part_of UBERON:0005236 ! osseus labyrinth vestibule synonym: "aqueductus vestibuli" RELATED LATIN [Wikipedia:Vestibular_aqueduct] xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray921.png [Term] id: UBERON:0002280 ! otolith name: otolith def: "Acellular structure composed of calcium carbonate located in the otolith organ." [Wikipedia:Otolith, ZFIN:curator] comment: Currently represented as part of the otolith membrane, but they may also be considered to be embedded in this membrane subset: uberon_slim subset: vertebrate_core synonym: "immature otolith" RELATED [] synonym: "immature otoliths" RELATED [] synonym: "otoconial crystal" RELATED [MP:0002894] synonym: "statolith" RELATED [] synonym: "otoliths" EXACT PLURAL [] synonym: "statoconium" EXACT [] synonym: "otoconium" EXACT [] synonym: "otoconia" EXACT PLURAL [] xref: FMA:77826 ! Otolith xref: TAO:0001621 ! otolith xref: ZFA:0001617 ! otolith xref: ncithesaurus:Otolith ! Otolith xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Bigotolith.jpg/200px-Bigotolith.jpg xref: ANISEED:777311 ! otolith xref: ANISEED:874485 ! otolith xref: SCTID:368951003 ! Entire otoconia is_a: UBERON:0000476 ! acellular anatomical structure relationship: part_of UBERON:0002519 {source="Wikipedia"} ! otolithic membrane relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: composed_primarily_of CHEBI:3311 ! calcium carbonate relationship: has_function_in GO:0009590 ! detection of gravity xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Bigotolith.jpg property_value: external_definition "Portion of organism substance composed of calcium carbonate located in the otolith organ.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001621", date_retrieved="2012-08-14", source="TAO:wd"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from immature otolith (TAO:0000139)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001621", date_retrieved="2012-08-14"} property_value: has_relational_adjective "otolithic" xsd:string property_value: has_relational_adjective "otoconial" xsd:string xref: UMLS:C0029894 [Term] id: UBERON:0006582 name: statolith def: "Acellular mineralized structure located in the statocyst (balance organ) of some aquatic invertebrates[WP,CJM]." [UBERON:cjm] synonym: "calcareousstatoliths" NARROW [] is_a: UBERON:0000476 ! acellular anatomical structure relationship: part_of UBERON:0006583 ! statocyst relationship: never_in_taxon NCBITaxon:7742 ! Vertebrata relationship: has_function_in GO:0009590 ! detection of gravity [Term] id: UBERON:0006583 name: statocyst def: "a balance sensory receptor present in some aquatic invertebrates[WP]." [Wikipedia:Statocyst] synonym: "statocyst organ" RELATED [] synonym: "balance organ" RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Statocyst.jpg/180px-Statocyst.jpg is_a: UBERON:0000062 ! organ relationship: capable_of GO:0050973 ! detection of mechanical stimulus involved in equilibrioception relationship: never_in_taxon NCBITaxon:7742 ! Vertebrata relationship: present_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha relationship: present_in_taxon NCBITaxon:6073 ! Cnidaria relationship: present_in_taxon NCBITaxon:6544 ! Bivalvia relationship: present_in_taxon NCBITaxon:6657 ! Crustacea relationship: present_in_taxon NCBITaxon:7586 ! Echinodermata relationship: dubious_for_taxon NCBITaxon:110815 {source="Wikipedia"} ! Xenoturbella subset: organ_slim [Term] id: UBERON:0012256 name: digestive syncytial vacuole comment: Taxon notes: in Aceola, Digestion is accomplished by means of a syncytium that forms a vacuole around ingested food. There are no epithelial cells lining the digestive vacuole, although there is sometimes a short pharynx leading from the mouth to the vacuole[WP] is_a: UBERON:0000470 ! cell part relationship: present_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha relationship: part_of CL:0000228 ! multinucleate cell relationship: part_of UBERON:0001007 ! digestive system [Term] id: UBERON:0002281 name: vestibular membrane of cochlear duct def: "a membrane inside the cochlea of the inner ear. It separates scala media from scala vestibuli. Together with the basilar membrane it creates a compartment in the cochlea filled with endolymph, which is important for the function of the organ of Corti. It primarily functions as a diffusion barrier, allowing nutrients to travel from the perilymph to the endolymph of the membranous labyrinth. Histologically, the membrane is composed of two layers of flattened epithelium, separated by a basal lamina. Its structure suggests that its function is transport of fluid and electrolytes." [Wikipedia:Reissner's_membrane] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "Reissner's membrane" EXACT [FMA:77829] synonym: "superior wall of cochlear duct" EXACT [FMA:77829] synonym: "vestibular membrane of Reissner" EXACT [FMA:77829] synonym: "vestibular membrane" EXACT [MA:0001200] synonym: "membrana vestibularis ductus cochlearis" EXACT [MP:0006021] synonym: "paries vestibularis ductus cochlearis" EXACT [MP:0006021] synonym: "vestibular membrane" RELATED [MP:0006021] synonym: "vestibular wall of cochlear duct" EXACT [MP:0006021] xref: FMA:77829 ! Vestibular membrane of cochlear duct xref: MA:0001200 ! vestibular membrane is_a: UBERON:0000094 ! membrane organ relationship: part_of UBERON:0001855 ! cochlear duct of membranous labyrinth relationship: adjacent_to UBERON:0001863 ! scala vestibuli relationship: adjacent_to UBERON:0002295 ! scala media xref: SCTID:362575002 ! Entire vestibular membrane xref: http://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Cochlea-crosssection.png/250px-Cochlea-crosssection.png [Term] id: UBERON:0011922 name: cochlear basement membrane def: "The the continuous basement membrane found within the membranous labyrinth of the cochlea, known to extend from the limbus, down to the inner sulcus, across the basilar membrane, up to the external sulcus to the spiral prominence and radiating into the spiral ligament ensheathing the root cell processes" [MP:0004598] intersection_of: UBERON:0005769 ! basement membrane intersection_of: part_of UBERON:0002499 ! cochlear labyrinth [Term] id: UBERON:0002282 ! stria vascularis of cochlear duct name: stria vascularis of cochlear duct def: "The upper portion of the spiral ligament contains numerous capillary loops and small blood vessels, and is termed the stria vascularis. It produces endolymph for the scala media, one of the three fluid-filled compartments of the cochlea. [WP,unvetted]." [Wikipedia:Stria_vascularis] comment: AO notes: represented as a wall in FMA. MESH def implies part of spiral ligament but better represented as adjacency / overlaps subset: uberon_slim synonym: "stria vascularis" EXACT [] synonym: "stria vascularis of cochlea" EXACT [FMA:77832] synonym: "stria vascularis ductus cochlearis" RELATED LATIN [BTO:0001819] synonym: "vascular stria of cochlear duct" RELATED [BTO:0001819] synonym: "vascular stripe of cochlear duct" EXACT [MP:0000048] synonym: "psalterial cord" EXACT [MP:0000048] xref: FMA:77832 ! Stria vascularis of cochlear duct xref: GAID:875 ! stria vascularis xref: MA:0001198 ! stria vascularis xref: NIF_GrossAnatomy:birnlex_2525 ! Stria Vascularis xref: BTO:0001819 ! stria vascularis xref: EFO:0001644 ! stria vascularis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c7/Cochlea-crosssection.png/200px-Cochlea-crosssection.png xref: MESH:A09.246.631.246.292.876 ! stria vascularis is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001855 {source="MA", source="FMA"} ! cochlear duct of membranous labyrinth relationship: has_developmental_contribution_from UBERON:0002342 {source="NBK53175", notes="pigment cells"} ! neural crest xref: SCTID:279842002 ! Entire stria vascularis of cochlea [Term] id: UBERON:0007352 name: stria vascularis vasculature def: "blood vessels supplying the stria vascularis in the cochlea of the inner ear." [MP:0004368] intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002282 ! stria vascularis of cochlear duct [Term] id: UBERON:0002285 name: telencephalic ventricle def: "A brain ventricle that is part of a telencephalon. In mammals and species with an evaginated telencephalon, this is one of a pair of lateral structures, one in each hemisphere" [Wikipedia:Lateral_ventricle, UBERON:cjm] comment: modeled as space in EHDAA2 subset: uberon_slim subset: vertebrate_core synonym: "telencephalic vesicle" RELATED [ZFA:0000696] synonym: "telencephalic ventricle" EXACT [ZFA:0000696, VHOG:0000643] synonym: "telencephalon lateral ventricle" EXACT [EHDAA2:0001984] synonym: "lateral ventricle of brain" RELATED [BTO:0000879] synonym: "lateral ventricle" EXACT [MA:0000192] synonym: "forebrain ventricle" RELATED [] synonym: "tectal ventricle" RELATED [] xref: BTO:0000879 xref: EHDAA:3502 ! lateral ventricle xref: EHDAA:6576 ! lateral ventricles xref: FMA:78448 ! Lateral ventricle xref: GAID:611 ! lateral ventricle xref: MA:0000192 ! lateral ventricle xref: NIF_GrossAnatomy:birnlex_1263 ! Lateral ventricle xref: OpenCyc:Mx4rvYsFdZwpEbGdrcN5Y29ycA xref: ZFA:0000696 ! telencephalic ventricle xref: EHDAA2:0001984 ! telencephalon lateral ventricle xref: ncithesaurus:Lateral_Ventricle ! Lateral Ventricle xref: EFO:0001961 ! lateral ventricle xref: OpenCyc:Mx4rvYsFdZwpEbGdrcN5Y29ycA ! lateral ventricle xref: VHOG:0000643 ! telencephalic ventricle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Gray734.png/200px-Gray734.png xref: MESH:A08.186.211.276.650 ! lateral ventricle xref: EV:0100307 ! lateral ventricle xref: BM:Tel-LV ! lateral ventricle intersection_of: UBERON:0004086 ! brain ventricle intersection_of: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0001869 {gci_relation="part_of", gci_filler="NCBITaxon:32523", notes="evaginated"} ! cerebral hemisphere relationship: in_lateral_side_of UBERON:0001893 {gci_relation="part_of", gci_filler="NCBITaxon:32523", notes="evaginated"} ! telencephalon relationship: develops_from UBERON:0009676 {source="EHDAA2", notes="material to immaterial"} ! early telencephalic vesicle xref: SCTID:180930008 ! Entire lateral ventricle xref: TAO:0000696 ! telencephalic ventricle property_value: homology_notes "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000643", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.381-382\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: external_definition "The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle[GO]." xsd:string {source="GO:0021670"} property_value: external_definition "The lateral ventricles are part of the ventricular system of the brain. Classified as part of the telencephalon, they are the largest of the ventricles. The lateral ventricles connect to the central third ventricle through the interventricular foramina of Monro[WP]." xsd:string {source="Wikipedia:Lateral_ventricle"} xref: UMLS:C0152279 [Term] id: UBERON:0013161 name: left lateral ventricle intersection_of: UBERON:0002285 ! telencephalic ventricle intersection_of: in_left_side_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0002812 {source="FMA"} ! left cerebral hemisphere synonym: "left telencephalic ventricle" EXACT [] xref: FMA:78450 ! left lateral ventricle xref: SCTID:368593005 ! Entire left lateral ventricle [Term] id: UBERON:0013162 name: right lateral ventricle intersection_of: UBERON:0002285 ! telencephalic ventricle intersection_of: in_right_side_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0002813 {source="FMA"} ! right cerebral hemisphere synonym: "right telencephalic ventricle" EXACT [] xref: FMA:78449 ! right lateral ventricle xref: SCTID:368571000 ! Entire right lateral ventricle [Term] id: UBERON:0005683 name: obsolete telencephalon lateral ventricle consider: EHDAA2:0001984 ! telencephalon lateral ventricle is_obsolete: true [Term] id: UBERON:0002286 name: third ventricle def: "Part of the ventricular system of the brain, forming a single large cavity in the midline of the diencephalon; it is continuous with the lateral ventricles through the interventricular foramen and the fourth ventricle through the cerebral aqueduct (Maryann Martone). A narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the HYPOTHALAMUS, its anterior wall by the lamina terminalis, and its roof by EPENDYMA. It communicates with the FOURTH VENTRICLE by the CEREBRAL AQUEDUCT, and with the LATERAL VENTRICLES by the interventricular foramina[GAID]." [Wikipedia:Third_ventricle, NIF_GrossAnatomy:birnlex_714, GAID:614] comment: Editor's note: consider adding class for secondary vesicle precursor subset: uberon_slim subset: vertebrate_core synonym: "3rd ventricle" EXACT [] synonym: "diencephalic ventricle" RELATED [] synonym: "diencephalic vesicle" NARROW [] synonym: "ventriculus diencephali" EXACT [ZFA:0000161] xref: FMA:78454 ! Third ventricle xref: GAID:614 ! third ventricle xref: VHOG:0000007 ! third ventricle xref: MA:0000182 ! third ventricle xref: NIF_GrossAnatomy:birnlex_714 ! Third ventricle xref: OpenCyc:Mx4rvakhcJwpEbGdrcN5Y29ycA xref: TAO:0000161 ! third ventricle xref: ZFA:0000161 ! third ventricle xref: ncithesaurus:Third_Ventricle_of_Brain ! Third Ventricle xref: OpenCyc:Mx4rvakhcJwpEbGdrcN5Y29ycA ! third ventricle xref: EHDAA2:0000084 ! 3rd ventricle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Gray734.png/200px-Gray734.png xref: EMAPA:16900 ! 3rd ventricle of diencephalon of forebrain xref: MESH:A08.186.211.276.840 ! third ventricle xref: EV:0100308 ! third ventricle xref: BM:Die-3V ! third ventricle is_a: UBERON:0004086 ! brain ventricle relationship: part_of UBERON:0001894 ! diencephalon relationship: develops_from UBERON:0006284 {source="EHDAA2"} ! prosencephalic vesicle xref: SCTID:180931007 ! Entire third ventricle synonym: "ventriculus tertius cerebri" RELATED LATIN [Wikipedia:Third_ventricle] xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray734.png property_value: external_definition "Fluid-filled brain cavity. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000161", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from forebrain ventricle (TAO:0001259)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000161", date_retrieved="2012-08-14"} property_value: homology_notes "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000007", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.381-382\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0149555 [Term] id: UBERON:0002287 name: optic recess of third ventricle def: "At the junction of the floor and anterior wall of the third ventricle, immediately above the optic chiasma, the ventricle presents a small angular recess or diverticulum, the optic recess (or supraoptic recess). [WP,unvetted]." [Wikipedia:Optic_recess] comment: TODO - check taxonomic grouping subset: uberon_slim subset: vertebrate_core synonym: "optic recess" EXACT [] synonym: "preoptic recess" EXACT [] synonym: "supraoptic recess" EXACT [] xref: EHDAA:1343 ! optic recess xref: EHDAA:1973 ! optic recess xref: EHDAA:2649 ! optic recess xref: EHDAA:3478 ! optic recess xref: FMA:78455 ! Optic recess of third ventricle xref: VHOG:0000595 ! optic recess xref: TAO:0000049 ! optic recess xref: ZFA:0000049 ! optic recess xref: EHDAA2:0001317 ! optic recess xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fa/Gray721.png/200px-Gray721.png xref: EMAPA:16644 ! optic recess of 3rd ventricle of diencephalon of future forebrain xref: EMAPA:16902 ! optic recess of 3rd ventricle of diencephalon of forebrain is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0002286 ! third ventricle synonym: "recessus supraopticus" EXACT LATIN [FMA:TA, FMA:78455] xref: SCTID:369279008 ! Entire optic recess of third ventricle synonym: "recessus supraopticus" RELATED LATIN [Wikipedia:Optic_recess] xref: http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray721.png synonym: "optic recesses" RELATED [VHOG:0000595] property_value: external_definition "The optic recess of the third ventricle, i.e. the pouch of the ventricle penetrating into the interval between the initial optic tracts. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000595", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002288 name: choroid plexus of third ventricle def: "A choroid plexus that is part of a third ventricle [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "3rd ventricle choroid plexus" RELATED [] synonym: "chorioid plexus of third ventricle" EXACT [] synonym: "third ventricle choroid plexus" EXACT [] synonym: "chorioid plexus of cerebral hemisphere of third ventricle" EXACT [OBOL:automatic] synonym: "third ventricle chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "choroid plexus third ventricle" EXACT [ZFA:0001444] synonym: "diencephalic choroid plexus " EXACT [ZFA:0001444] xref: FMA:78462 ! Choroid plexus of third ventricle xref: MA:0000879 ! third ventricle choroid plexus xref: ZFA:0001444 ! choroid plexus third ventricle xref: VHOG:0001374 ! choroid plexus third ventricle is_a: UBERON:0001886 ! choroid plexus of cerebral hemisphere intersection_of: UBERON:0001886 ! choroid plexus of cerebral hemisphere intersection_of: part_of UBERON:0002286 ! third ventricle relationship: part_of UBERON:0002286 ! third ventricle xref: ncithesaurus:Choroid_Plexus_of_the_Third_Ventricle ! Choroid Plexus of the Third Ventricle xref: SCTID:61576002 ! Entire choroid plexus of third ventricle xref: TAO:0001444 ! choroid plexus third ventricle xref: UMLS:C0152291 [Term] id: UBERON:0002289 name: midbrain cerebral aqueduct alt_id: UBERON:0005684 def: "The mesencephalic duct, also known as the aqueductus mesencephali, aqueduct of Sylvius or the cerebral aqueduct, contains cerebrospinal fluid (CSF), is within the mesencephalon (or midbrain) and connects the third ventricle in the diencephalon to the fourth ventricle, which is between the pons and cerebellum. [WP,unvetted]." [Wikipedia:Cerebral_aqueduct] comment: AO notes: Two distinct classes in ncit. We classify this as a brain ventricle even though it is not classifically regarded as one (3rd = diencephalon, 4th = hindbrains) subset: uberon_slim subset: vertebrate_core synonym: "mesencephalic duct" EXACT [Wikipedia:Cerebral_aqueduct] synonym: "Sylvian aqueduct" EXACT [Wikipedia:Cerebral_aqueduct] synonym: "aqueduct (Sylvius)" EXACT [] synonym: "aqueduct of midbrain" EXACT [] synonym: "aqueduct of Sylvius" EXACT [] synonym: "cerebral aqueduct of Sylvius" EXACT [] synonym: "cerebral aquaduct" EXACT [ZFA:0000159] synonym: "tectal ventricle" EXACT [ZFA:0000159] synonym: "midbrain cerebral aqueduct" EXACT [EHDAA2:0001163] synonym: "medial tectal ventricle" EXACT [ZFA:0000159] synonym: "mesencephalic ventricle" EXACT [ZFA:0000159] synonym: "mesencephalic vesicle" RELATED [ZFA:0000159] synonym: "midbrain ventricle" EXACT [ZFA:0000159] synonym: "cerebral aqueduct" EXACT [MA:0000208] synonym: "aqueductus mesencephali" EXACT LATIN [FMA:TA, FMA:78467] synonym: "aqueductus mesencephali" RELATED LATIN [Wikipedia:Cerebral_aqueduct] xref: EHDAA:3696 ! midbrain cerebral aqueduct xref: FMA:78467 ! Cerebral aqueduct xref: GAID:583 ! cerebral aqueduct xref: VHOG:0000832 ! cerebral aqueduct xref: MA:0000208 ! cerebral aqueduct xref: NIF_GrossAnatomy:birnlex_1261 ! Cerebral aqueduct xref: ZFA:0000159 ! tectal ventricle xref: EHDAA2:0001163 ! midbrain cerebral aqueduct xref: ncithesaurus:Aqueduct_of_Sylvius ! Aqueduct of Sylvius xref: ncithesaurus:Cerebral_Aqueduct ! Cerebral Aqueduct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Cn3nucleus.png/200px-Cn3nucleus.png xref: EMAPA:17795 ! cerebral aqueduct xref: MESH:A08.186.211.132.659.822.187 ! cerebral aqueduct xref: EV:0100309 ! cerebral aqueduct xref: BM:MB-AQ ! cerebral aqueduct xref: EFO:0003501 ! tectal ventricle is_a: UBERON:0004086 ! brain ventricle relationship: part_of UBERON:0001891 ! midbrain relationship: develops_from UBERON:0013148 {source="EHDAA2"} ! midbrain vesicle xref: SCTID:279249003 ! Entire cerebral aqueduct xref: TAO:0000159 ! tectal ventricle xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Cn3nucleus.png property_value: homology_notes "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000832", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.381-382\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0007769 [Term] id: UBERON:0002721 name: lateral sulcus def: "A sulcus that divides the frontal lobe and parietal lobe above from the temporal lobe below. It is in both hemispheres of the brain but is longer in the left hemisphere. The lateral sulcus is one of the earliest-developing sulci of the human brain. It first appears around the fourteenth gestational week[WP,modified]." [Wikipedia:Lateral_sulcus] subset: uberon_slim synonym: "Sylvian sulcus" EXACT [UBERON:cjm] synonym: "fissure of Sylvius" EXACT [] synonym: "lateral cerebral fissure" EXACT [FMA:77801] synonym: "lateral cerebral sulcus" EXACT [FMA:77801] synonym: "lateral fissure" EXACT [FMA:77801] synonym: "lateral fissure of Sylvius" EXACT [] synonym: "lateral cerebral fissure" EXACT [] synonym: "transverse cerebral fissure" EXACT [FMA:77801] synonym: "fissura lateralis" EXACT [NIF_GrossAnatomy:birnlex_1487] synonym: "fissura lateralis cerebri" EXACT [NIF_GrossAnatomy:birnlex_1487] synonym: "fissura lateralis cerebri (sylvii)" EXACT [NIF_GrossAnatomy:birnlex_1487] synonym: "sulcus lateralis" EXACT [NIF_GrossAnatomy:birnlex_1487] synonym: "Sylvian fissure" EXACT [NIF_GrossAnatomy:birnlex_1487] synonym: "sulcus lateralis cerebri" EXACT LATIN [FMA:TA, FMA:77801] synonym: "fissura transversa cerebri" EXACT LATIN [FMA:TA, FMA:77801] synonym: "sulcus lateralis cerebri" EXACT LATIN [Wikipedia:Lateral_sulcus] xref: FMA:77801 ! Lateral sulcus xref: NIF_GrossAnatomy:birnlex_1487 ! Lateral sulcus xref: ncithesaurus:Fissure_of_Sylvius ! Fissure of Sylvius xref: BM:Tel-Cx-LS ! lateral sulcus is_a: UBERON:0008334 {source="FMA"} ! subarachnoid sulcus xref: http://upload.wikimedia.org/wikipedia/commons/4/41/Lateral_sulcus2.png xref: SCTID:369226003 ! Entire fissure of Sylvius xref: UMLS:C0228187 [Term] id: UBERON:0013591 name: postsylvian sulcus is_a: UBERON:0008334 ! subarachnoid sulcus [Term] id: UBERON:0013592 name: presylvian sulcus is_a: UBERON:0008334 ! subarachnoid sulcus [Term] id: UBERON:0013593 name: suprasylvian sulcus is_a: UBERON:0008334 ! subarachnoid sulcus [Term] id: UBERON:0013594 name: ectosylvian sulcus is_a: UBERON:0008334 ! subarachnoid sulcus [Term] id: UBERON:0013595 name: postlateral sulcus is_a: UBERON:0008334 ! subarachnoid sulcus [Term] id: UBERON:0013596 name: brain coronal sulcus synonym: "coronal sulcus" BROAD INCONSISTENT [] synonym: "coronal sulcus of brain" EXACT [] is_a: UBERON:0008334 ! subarachnoid sulcus [Term] id: UBERON:0013598 name: accessory nucleus of optic tract def: "One of a set of small groups of neuron cell bodies located along the trajectory of optic fibers in the mesencephalon. These consist of the posterior nucleus [TA] (nucleus posterior [TA]), medial nucleus [TA] (nucleus medialis [TA]), and lateral nucleus [TA] (nucleus lateralis [TA]), which are also called the posterior, medial, and lateral terminal nuclei. The connections of these nuclei, along with the nucleus of the optic tract, make up the accessory optic system that appears to be concerned with retinal slip in specific directions" [http://www.medilexicon.com/medicaldictionary.php?t=61308] synonym: "nuclei accessorii tractus optici" EXACT LATIN [] synonym: "nucleus of accessory optic system" EXACT [] is_a: UBERON:0002308 {source="FMA"} ! nucleus of brain relationship: part_of UBERON:0001891 ! midbrain xref: FMA:256154 ! accessory nucleus of optic tract [Term] id: UBERON:0013599 name: dorsal accessory nucleus of optic tract synonym: "posterior accessory nucleus of optic tract" EXACT [FMA:77651] is_a: UBERON:0013598 {source="FMA"} ! accessory nucleus of optic tract xref: FMA:77651 ! Dorsal accessory nucleus of optic tract xref: ABA:DT ! Dorsal terminal nucleus of the accessory optic tract synonym: "dorsal terminal nucleus of the accessory optic tract" EXACT [ABA:DT] synonym: "posterior terminal nucleus of accessory optic tract" EXACT [] synonym: "dorsal terminal nucleus of accessory optic tract" EXACT [] [Term] id: UBERON:0013600 name: lateral accessory nucleus of optic tract is_a: UBERON:0013598 {source="FMA"} ! accessory nucleus of optic tract xref: FMA:77652 ! Lateral accessory nucleus of optic tract xref: ABA:LT ! Lateral terminal nucleus of the accessory optic tract synonym: "lateral terminal nucleus of the accessory optic tract" EXACT [ABA:LT] [Term] id: UBERON:0013601 name: medial accessory nucleus of optic tract comment: The medial terminal nucleus is usually very prominent but it is reduced in primates (except, curiously, the tarsier), megachiropterans, Cynocephalus and Bradypus. Metatherians have a large medial terminal nucleus[Pettigrew et al. (1989)] is_a: UBERON:0013598 {source="FMA"} ! accessory nucleus of optic tract xref: FMA:77653 ! Medial accessory nucleus of optic tract xref: ABA:MT ! Medial terminal nucleus of the accessory optic tract synonym: "medial terminal nucleus of the accessory optic tract" EXACT [ABA:MT] [Term] id: UBERON:0002737 name: lateral inferior limiting sulcus xref: FMA:74523 ! Lateral inferior limiting sulcus xref: NIF_GrossAnatomy:birnlex_1540 ! Lateral inferior limiting sulcus is_a: UBERON:0008334 {source="FMA"} ! subarachnoid sulcus [Term] id: UBERON:0002290 name: choroid plexus of fourth ventricle def: "A choroid plexus that is part of a fourth ventricle [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "4th ventricle choroid plexus" RELATED [] synonym: "chorioid plexus of fourth ventricle" EXACT [] synonym: "fourth ventricle choroid plexus" EXACT [] synonym: "chorioid plexus of cerebral hemisphere of fourth ventricle" EXACT [OBOL:automatic] synonym: "fourth ventricle chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "choroid plexus fourth ventricle" EXACT [ZFA:0001446] xref: FMA:78492 ! Choroid plexus of fourth ventricle xref: MA:0000983 ! fourth ventricle choroid plexus xref: ZFA:0001446 ! choroid plexus fourth ventricle xref: VHOG:0001375 ! choroid plexus fourth ventricle is_a: UBERON:0001886 ! choroid plexus of cerebral hemisphere intersection_of: UBERON:0001886 ! choroid plexus of cerebral hemisphere intersection_of: part_of UBERON:0002422 ! fourth ventricle relationship: part_of UBERON:0002037 ! cerebellum xref: ncithesaurus:Choroid_Plexus_of_the_Fourth_Ventricle ! Choroid Plexus of the Fourth Ventricle xref: SCTID:42214001 ! Entire choroid plexus of fourth ventricle xref: TAO:0001446 ! choroid plexus fourth ventricle xref: UMLS:C0152293 [Term] id: UBERON:0009571 ! ventral midline name: ventral midline def: "In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate." [GOC:bf, GOC:go_curators, PMID:12075342] is_a: UBERON:0002050 {source="FMA"} ! embryonic structure xref: FBbt:00000093 ! ventral midline [Term] id: UBERON:0002291 ! central canal name: central canal alt_id: UBERON:0002220 def: "Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." [ZFIN:curator] comment: previously mapped to FMA:75364. Note some ontologies (NIF, SNOMED) subdivide this into lumbar, thoracic, etc. Note we follow FMA in distinguishing between the canal and the lumen subset: uberon_slim subset: vertebrate_core synonym: "central canal of spinal cord" EXACT [] synonym: "neural lumen" RELATED [] synonym: "spinal cord central canal" EXACT [] synonym: "ventricle of spinal cord" EXACT [FMA:78497] synonym: "canalis centralis" EXACT [ZFA:0000938] xref: FMA:78497 ! Central canal of spinal cord xref: MA:0001117 ! spinal cord central canal xref: NIF_GrossAnatomy:birnlex_1409 xref: TAO:0000938 ! central canal xref: ZFA:0000938 ! central canal xref: ncithesaurus:Central_Canal ! Central Canal of Spinal Cord xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Medulla_spinalis_-_Section_-_English.svg/200px-Medulla_spinalis_-_Section_-_English.svg.png is_a: UBERON:0004111 {source="cjm"} ! anatomical conduit relationship: part_of UBERON:0002240 {source="MA"} ! spinal cord relationship: has_part UBERON:0001359 ! cerebrospinal fluid relationship: develops_from UBERON:0001049 ! neural tube relationship: part_of UBERON:0005281 {source="FMA"} ! ventricular system of central nervous system xref: SCTID:279447004 ! Entire central spinal cord canal xref: EHDAA2:0004361 ! spinal cord central canal xref: UMLS:C0459414 [Term] id: UBERON:0009572 name: lumen of central canal of spinal cord def: "A cerebrospinal fluid-filled space that runs longitudinally through the length of the entire spinal cord. The central canal is contiguous with the ventricular system of the brain. The central canal represents the adult remainder of the neural tube." [Wikipedia:Central_canal] synonym: "cavity of central canal of spinal cord" EXACT [FMA:242845] synonym: "central canal lumen" EXACT [UBERON:cjm] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0002291 ! central canal relationship: part_of UBERON:0002291 ! central canal relationship: surrounds UBERON:0001359 ! cerebrospinal fluid relationship: part_of UBERON:0005281 {source="FMA-modified"} ! ventricular system of central nervous system xref: FMA:242845 ! lumen of central canal of spinal cord [Term] id: UBERON:0001173 name: biliary tree def: "Hollow tree organ, the organ parts of which consists of the bile ducts[FMA]." [Wikipedia:Biliary_tract, FMA:14665] subset: uberon_slim synonym: "biliary tract" EXACT [] xref: FMA:14665 ! Biliary tree xref: XAO:0000455 ! biliary tree xref: GAID:279 ! biliary tract xref: MA:0001273 ! biliary tract xref: ncithesaurus:Biliary_Tract ! Biliary Tract xref: MESH:A03.159 ! biliary tract is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0002294 ! biliary system relationship: develops_from UBERON:0004912 ! biliary bud xref: AAO:0011020 ! biliary tree xref: SCTID:181267003 ! Entire biliary tract subset: organ_slim property_value: external_definition "Hollow tree organ, the organ parts of which consist of the bile ducts.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011020", date_retrieved="2012-06-20", source="UBERON:0001173"} xref: UMLS:C0005423 [Term] id: UBERON:0002294 name: biliary system def: "Anatomical system that consists of the organs and ducts (bile ducts, gallbladder, and associated structures) that are involved in the production and transportation of bile." [Wikipedia:Biliary_system] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "biliary apparatus" EXACT [] xref: FMA:79646 ! Biliary system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5d/Digestive_system_showing_bile_duct.png/200px-Digestive_system_showing_bile_duct.png is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system relationship: part_of UBERON:0002423 ! hepatobiliary system xref: SCTID:361354009 ! Entire biliary system [Term] id: UBERON:0002295 name: scala media def: "An endolymph filled cavity inside the cochlea, located in between the scala tympani and the scala vestibuli, separated by the basilar membrane and Reissner's membrane (the vestibular membrane) respectively. Scala media houses the organ of Corti. [WP,unvetted]." [Wikipedia:Scala_media] comment: TODO: check cochlear duct vs cochlear aqueduct vs scala media subset: uberon_slim synonym: "cochlear duct" RELATED [] xref: FMA:79789 ! Scala media xref: MA:0002458 ! scala media xref: EHDAA2:0000262 ! cochlear duct (also: UBERON:0001855 'cochlear duct of membranous labyrinth') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bc/Gray928.png/200px-Gray928.png is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001844 ! cochlea [Term] id: UBERON:0009664 name: gut mesentery is_a: UBERON:0000477 {source="EHDAA2"} ! anatomical cluster relationship: located_in UBERON:0001179 {source="EHDAA2"} ! peritoneal cavity xref: EHDAA2:0004566 ! gut mesentery [Term] id: UBERON:0002296 ! dorsal mesentery name: dorsal mesentery def: "The mesentery that originates from the dorsal side of the peritoneal cavity[ZFA]." [Wikipedia:Dorsal_mesentery, Wikipedia:Mesentery#Development, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "dorsal mesogastrium" RELATED [Wikipedia:Dorsal_mesentery] xref: EHDAA:3019 ! dorsal mesentery xref: EHDAA:3033 ! dorsal mesentery xref: EHDAA:3921 ! dorsal mesentery xref: EHDAA:3934 ! dorsal mesentery xref: EHDAA:3957 ! dorsal mesentery xref: EHDAA:3971 ! dorsal mesentery xref: EHDAA2:0004560 ! dorsal mesentery xref: FMA:79795 ! Dorsal mesentery xref: TAO:0005130 ! dorsal mesentery xref: ZFA:0005130 ! dorsal mesentery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/85/Gray985.png/200px-Gray985.png is_a: UBERON:0002050 {source="FMA"} ! embryonic structure relationship: part_of UBERON:0009664 {source="EHDAA2"} ! gut mesentery relationship: develops_into UBERON:0002095 ! mesentery xref: SCTID:308823000 ! Entire dorsal mesentery synonym: "mesenterium dorsale commune" RELATED LATIN [Wikipedia:Dorsal_mesentery] xref: http://upload.wikimedia.org/wikipedia/commons/8/85/Gray985.png property_value: external_definition "The mesentery that originates from the dorsal side of the peritoneal cavity.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005130", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005602 name: dorsal mesogastrium def: "The portion of mesentery attached to the greater curvature of the stomach is named the dorsal mesentery (or dorsal mesogastrium, when referring to the portion at the stomach), and the part which suspends the colon is termed the mesocolon. The dorsal mesogastrium develops into the greater omentum." [Wikipedia:Dorsal_mesentery] synonym: "dorsal mesentery" RELATED [Wikipedia:Dorsal_mesentery] xref: MA:0001618 ! dorsal mesogastrium xref: EHDAA2:0000416 ! dorsal mesogastrium xref: EMAPA:17025 ! dorsal mesogastrium of mesentery of stomach of foregut xref: EMAPA:18903 ! dorsal mesogastrium of mesentery of stomach of gut xref: VHOG:0000352 ! dorsal mesogastrium xref: EHDAA:3001 ! dorsal mesogastrium is_a: UBERON:0003281 {source="MA"} ! mesentery of stomach relationship: part_of UBERON:0003281 {source="EHDAA2"} ! mesentery of stomach relationship: part_of UBERON:0002296 {source="EHDAA2"} ! dorsal mesentery xref: ncithesaurus:Dorsal_Mesogastrium ! Dorsal Mesogastrium property_value: external_definition "The dorsal sheet of the primitive mesentery that encloses the stomach. The greater omentum develops from the dorsal mesogastrium. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000352", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/mesogastrium", source="http://bgee.unil.ch/"} xref: UMLS:C1512038 [Term] id: UBERON:0009668 name: ventral mesentery is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0009664 {source="EHDAA2"} ! gut mesentery xref: EHDAA2:0004569 ! ventral mesentery xref: SCTID:361430000 ! Ventral mesentery [Term] id: UBERON:0005626 name: ventral mesogastrium def: "Ventral mesentery is the part of the peritoneum closest to the navel." [Wikipedia:Ventral_mesentery] comment: "The primitive gut is enveloped by a mesentery that has a dorsal and a ventral aspect. The ventral mesentery degenerates during development with the exception of the foregut ventral mesentery, which develops into specialized structures (see foregut embryology)" [http://sprojects.mmi.mcgill.ca/embryology/gi/pgm.htm]. todo - check subset: vertebrate_core synonym: "ventral mesentery" RELATED [Wikipedia:Ventral_mesentery] xref: MA:0001621 ! ventral mesogastrium xref: EHDAA2:0002176 ! ventral mesogastrium xref: ZFA:0005133 ! ventral mesentery xref: EMAPA:17026 ! ventral mesogastrium of mesentery of stomach of foregut xref: EMAPA:18907 ! ventral mesogastrium of mesentery of stomach of gut xref: VHOG:0000351 ! ventral mesogastrium xref: EHDAA:3005 ! ventral mesogastrium is_a: UBERON:0003281 ! mesentery of stomach relationship: part_of UBERON:0003281 {source="EHDAA2"} ! mesentery of stomach relationship: part_of UBERON:0009668 {source="EHDAA2"} ! ventral mesentery xref: ncithesaurus:Ventral_Mesogastrium ! Ventral Mesogastrium xref: TAO:0005133 ! ventral mesentery xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Gray984.png property_value: external_definition "The mesentery that originates from the ventral side of the peritoneal cavity.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005133", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "The ventral sheet of the primitive mesentery that encloses the stomach. The lesser omentum develops from the ventral mesogastrium. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000351", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/mesogastrium", source="http://bgee.unil.ch/"} xref: UMLS:C1519967 [Term] id: UBERON:0003281 name: mesentery of stomach def: "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum." [http://medical-dictionary.thefreedictionary.com/mesogastrium] comment: todo - check primitive vs developed synonym: "stomach mesentery" EXACT [Obol:obol] synonym: "mesogastium" EXACT [MA:0001617] synonym: "mesogaster" EXACT [http://medical-dictionary.thefreedictionary.com/mesogastrium] synonym: "mesogastrium" EXACT [http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html] synonym: "mesentery of ventriculus" EXACT [OBOL:automatic] synonym: "ventriculus mesentery" EXACT [OBOL:automatic] xref: EHDAA:2999 ! mesentery xref: MA:0001617 ! stomach mesentery xref: VHOG:0000358 ! mesogastrium xref: EHDAA2:0001922 ! stomach mesentery xref: EMAPA:17024 ! mesentery of stomach of foregut xref: EMAPA:18902 ! mesentery of stomach of gut is_a: UBERON:0004854 {source="MA"} ! gastrointestinal system mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0000945 {source="MA"} ! stomach xref: SCTID:261623000 ! Entire mesogastrium property_value: external_definition "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000358", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/mesogastrium", source="http://bgee.unil.ch/"} [Term] id: UBERON:0013211 name: cerumen gland def: "A specialized sudoriferous gland (sweat glands) located subcutaneously in the external auditory canal. Ceruminous glands are simple, coiled, tubular glands made up of an inner secretory layer of cells and an outer myoepithelial layer of cells. The glands drain into larger ducts, which then drain into the guard hairs that reside in the external auditory canal. Here they produce cerumen, or earwax, by mixing their secretion with sebum and dead epidermal cells. Cerumen keeps the eardrum pliable, lubricates and cleans the external auditory canal, waterproofs the canal, kills bacteria, and serves as a barrier to trap foreign particles (dust, fungal spores, etc.) by coating the guard hairs of the ear, making them sticky." [Wikipedia:Ceruminous_glands] synonym: "ceruminous gland" EXACT [] synonym: "cerumen-secreting gland" EXACT [] is_a: UBERON:0000382 ! apocrine sweat gland relationship: located_in UBERON:0001352 ! external acoustic meatus relationship: part_of UBERON:0001691 ! external ear relationship: secretes UBERON:0002297 ! cerumen xref: ncithesaurus:Ceruminous_Gland ! ceruminous gland xref: SCTID:368648008 ! Entire ceruminous gland xref: UMLS:C0229352 [Term] id: UBERON:0002297 name: cerumen def: "The yellow or brown waxy secretions produced by vestigial apocrine sweat glands in the external ear canal[MESH]." [MESH:A12.200.147, Wikipedia:Cerumen] subset: uberon_slim synonym: "ear wax" EXACT [] xref: ENVO:02000028 xref: FMA:79869 ! Cerumen xref: GAID:1158 ! cerumen xref: MA:0002506 ! cerumen xref: ncithesaurus:Cerumen ! Cerumen xref: MESH:A12.200.147 ! cerumen is_a: UBERON:0000456 ! bodily secretion relationship: located_in UBERON:0001352 ! external acoustic meatus property_value: has_relational_adjective "cerumenous" xsd:string property_value: has_relational_adjective "cerumenal" xsd:string xref: UMLS:C0740486 [Term] id: UBERON:0002300 name: obsolete ventricle is_obsolete: true def: "A chamber of an organ with cavitated organ parts. Examples: right ventricle of heart, lateral ventricle of brain." [Wikipedia:Ventricle_of_the_larynx] consider: FMA:82553 ! Ventricle [Term] id: UBERON:0002301 name: layer of neocortex comment: This class was created automatically from a combination of ontologies synonym: "cerebral cortex layer" RELATED [MA:0000186] synonym: "neocortex layer" EXACT [] synonym: "cortical layer" EXACT [] xref: FMA:83138 ! Layer of neocortex xref: MA:0000186 ! neocortex layer xref: ABA:CTX1-6b ! Cerebral cortex, layers 1-6b is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001950 ! neocortex [Term] id: UBERON:0005390 name: cortical layer I def: "The most superficial layer of the neocortex characterized by a paucity of cell bodies." [NIF_GrossAnatomy:nlx_anat_090807] synonym: "molecular layer" RELATED [] synonym: "plexiform layer" RELATED [] synonym: "molecular layer of neocortex" EXACT [FMA:83900] synonym: "neocortex layer I" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "layer 1 of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "layer I of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "molecular layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "neocortex layer 1" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "neocortex molecular layer" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "neocortex plexiform layer" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "plexiform layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090807] synonym: "molecular layer of isocortex [layer i]" EXACT [FMA:83900] synonym: "cerebral cortex, layer 1" EXACT [ABA:CTX1] synonym: "molecular layer of cerebral cortex" EXACT [ncithesaurus:Molecular_layer] xref: MA:0000897 ! cortical layer I xref: FMA:83900 ! Molecular layer of neocortex xref: NIF_GrossAnatomy:nlx_anat_090807 ! Neocortex layer 1 xref: BTO:0004906 ! molecular layer xref: ABA:CTX1 ! Cerebral cortex, layer 1 xref: ncithesaurus:Molecular_Layer ! Molecular Layer of the Cerebral Cortex is_a: UBERON:0002301 ! layer of neocortex synonym: "lamina molecularis isocorticis [lamina i]" EXACT LATIN [FMA:TA, FMA:83900] xref: UMLS:C1709063 [Term] id: UBERON:0005391 name: cortical layer II def: "Layer of neocortex lying just deep to molecular layer characterized by numerous small cell bodies." [NIF_GrossAnatomy:nlx_anat_090808] synonym: "external granule cell layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090808] synonym: "layer II of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090808] synonym: "neocortex layer 2" EXACT [NIF_GrossAnatomy:nlx_anat_090808] synonym: "neocortex layer II" EXACT [NIF_GrossAnatomy:nlx_anat_090808] synonym: "external granular layer" RELATED [] synonym: "external granular layer of cerebral cortex" RELATED [] synonym: "external granular layer of neocortex" EXACT [FMA:77804] synonym: "external granular layer of isocortex [layer ii]" EXACT [FMA:77804] synonym: "cerebral cortex, layer 2" EXACT [ABA:CTX2] xref: MA:0000898 ! cortical layer II xref: FMA:77804 ! External granular layer of neocortex xref: NIF_GrossAnatomy:nlx_anat_090808 ! Neocortex layer 2 xref: ABA:CTX2 ! Cerebral cortex, layer 2 xref: ncithesaurus:External_Granular_Layer ! External Granular Layer of the Cerebral Cortex is_a: UBERON:0002301 ! layer of neocortex relationship: immediately_deep_to UBERON:0005390 ! cortical layer I synonym: "lamina granularis externa isocorticis [lamina ii]" EXACT LATIN [FMA:TA, FMA:77804] xref: UMLS:C1517039 [Term] id: UBERON:0005392 name: cortical layer III def: "Layer of neocortex lying deep to the external granule cell layer defined cytoarchitecturally by numerous small pyramidal neurons." [NIF_GrossAnatomy:nlx_anat_090809] synonym: "external pyramidal cell layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090809] synonym: "layer 3 of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090809] synonym: "layer III of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090809] synonym: "neocortex external pyramidal cell layer" EXACT [NIF_GrossAnatomy:nlx_anat_090809] synonym: "neocortex layer 3" EXACT [NIF_GrossAnatomy:nlx_anat_090809] synonym: "neocortex layer III" EXACT [NIF_GrossAnatomy:nlx_anat_090809] synonym: "pyramidal layer" RELATED [] synonym: "external pyramidal layer of neocortex" EXACT [FMA:77810] synonym: "external pyramidal cell layer" EXACT [FMA:77810] synonym: "external pyramidal layer of isocortex [layer iii]" EXACT [FMA:77810] synonym: "external pyramidal layer of cerebral cortex" RELATED [ncithesaurus:External_Pyramidal_Cell_Layer] synonym: "cerebral cortex, layer 3" EXACT [ABA:CTX3] xref: ABA:CTX3 ! Cerebral cortex, layer 3 xref: MA:0000899 ! cortical layer III xref: FMA:77810 ! External pyramidal layer of neocortex xref: NIF_GrossAnatomy:nlx_anat_090809 ! Neocortex layer 3 xref: ncithesaurus:External_Pyramidal_Cell_Layer ! External Pyramidal Cell Layer of the Cerebral Cortex is_a: UBERON:0002301 ! layer of neocortex relationship: immediately_deep_to UBERON:0005391 ! cortical layer II synonym: "lamina pyramidalis externa isocorticis [lamina iii]" EXACT LATIN [FMA:TA, FMA:77810] xref: UMLS:C1517046 [Term] id: UBERON:0005393 name: cortical layer IV def: "Layer of neocortex lying deep to the external pyramidal cell layer defined cytoarchitecturally by the presence of numerous small cells" [NIF_GrossAnatomy:nlx_anat_090810] synonym: "internal granule cell layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "layer 4 of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "layer IV of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "neocortex internal granule cell layer" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "neocortex layer 4" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "neocortex layer IV" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "neocortical internal granule cell layer" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "neocortical layer IV" EXACT [NIF_GrossAnatomy:nlx_anat_090810] synonym: "internal granular layer" RELATED [] synonym: "internal granular layer of neocortex" EXACT [FMA:77811] synonym: "internal granular layer of isocortex [layer iv]" EXACT [FMA:77811] synonym: "cerebral cortex, layer 4" EXACT [ABA:CTX4] xref: MA:0000900 ! cortical layer IV xref: FMA:77811 ! Internal granular layer of neocortex xref: NIF_GrossAnatomy:nlx_anat_090810 ! Neocortex layer 4 xref: ABA:CTX4 ! Cerebral cortex, layer 4 xref: ncithesaurus:Internal_Granular_Layer ! Internal Granular Layer of the Cerebral Cortex is_a: UBERON:0002301 ! layer of neocortex relationship: immediately_deep_to UBERON:0005392 ! cortical layer III synonym: "lamina granularis interna isocorticis [lamina iv]" EXACT LATIN [FMA:TA, FMA:77811] xref: UMLS:C1512872 [Term] id: UBERON:0005394 name: cortical layer V def: "Layer of neocortex lying deep to the internal granule cell layer (layer 4) defined cytoarchitecturally by the predominance of large pyramidal cell bodies" [NIF_GrossAnatomy:nlx_anat_090811] synonym: "internal pyramidal cell layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "layer 5 of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "layer V of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "neocortex internal pyramidal cell layer" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "neocortex layer 5" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "neocortex layer V" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "neocortical layer 5" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "neocortical layer V" EXACT [NIF_GrossAnatomy:nlx_anat_090811] synonym: "ganglionic layer" RELATED [] synonym: "ganglionic layer of cerebral cortex" RELATED [] synonym: "internal pyramidal layer of neocortex" EXACT [FMA:77812] synonym: "betz' cells" EXACT [FMA:77812] synonym: "internal pyramidal layer of isocortex [layer v]" EXACT [FMA:77812] synonym: "cerebral cortex, layer 5" EXACT [ABA:CTX5] xref: MA:0000901 ! cortical layer V xref: FMA:77812 ! Internal pyramidal layer of neocortex xref: NIF_GrossAnatomy:nlx_anat_090811 ! Neocortex layer 5 xref: ABA:CTX5 ! Cerebral cortex, layer 5 xref: ncithesaurus:Ganglionic_Layer ! Ganglionic Layer of the Cerebral Cortex is_a: UBERON:0002301 ! layer of neocortex relationship: immediately_deep_to UBERON:0005393 ! cortical layer IV synonym: "lamina pyramidalis interna isocorticis [lamina v]" EXACT LATIN [FMA:TA, FMA:77812] xref: UMLS:C1517447 [Term] id: UBERON:0005395 name: cortical layer VI def: "Innermost layer of neocortex lying deep to the internal pyramidal cell layer defined cytoarchitecturally by cells of varying size." [NIF_GrossAnatomy:nlx_anat_090812] synonym: "layer VI of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "multiform layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "neocortex layer 6" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "neocortex layer VI" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "neocortex multiform layer" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "neocortical layer 6" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "neocortical layer VI" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "pleiomorphic layer of neocortex" EXACT [NIF_GrossAnatomy:nlx_anat_090812] synonym: "multiform layer" RELATED [] synonym: "multiform layer of neocortex" EXACT [FMA:77805] synonym: "multiform layer of isocortex [layer vi]" EXACT [FMA:77805] synonym: "cerebral cortex, layer 6 " EXACT [ABA:CTX6] xref: MA:0000902 ! cortical layer VI xref: FMA:77805 ! Multiform layer of neocortex xref: NIF_GrossAnatomy:nlx_anat_090812 ! Neocortex layer 6 xref: ABA:CTX6 ! Cerebral cortex, layer 6 is_a: UBERON:0002301 ! layer of neocortex relationship: immediately_deep_to UBERON:0005394 ! cortical layer V synonym: "lamina multiformis isocorticis [lamina vi]" EXACT LATIN [FMA:TA, FMA:77805] [Term] id: UBERON:0005168 ! interlobular vein name: interlobular vein def: "The venae stellatae join to form the interlobular veins, which pass inward between the rays, receive branches from the plexuses around the convoluted tubules, and, having arrived at the bases of the renal pyramids, join with the venae rectae" [Wikipedia:Interlobular_veins] xref: EMAPA:28218 ! interlobular vein xref: MA:0002594 ! interlobular vein xref: FMA:71634 ! set of interlobular veins of kidney xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/27/Gray1128.png/200px-Gray1128.png is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0001225 ! cortex of kidney synonym: "venae interlobulares renis" EXACT LATIN [FMA:TA, FMA:71634] synonym: "venae interlobulares renis" RELATED LATIN [Wikipedia:Interlobular_veins] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray1128.png synonym: "set of interlobular veins of kidney" RELATED [FMA:71634] synonym: "interlobular veins of kidney" RELATED [FMA:71634] [Term] id: UBERON:0002303 name: juxtaglomerular apparatus def: "An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]." [GO:0072206, Wikipedia:Juxtaglomerular_apparatus] subset: uberon_slim synonym: "complexus juxtaglomerularis" RELATED LATIN [] synonym: "juxtaglomerular complex" EXACT [] xref: FMA:83599 ! Juxtaglomerular complex xref: GAID:432 ! juxtaglomerular apparatus xref: MA:0002546 ! juxtaglomerular complex xref: EMAPA:30449 ! juxtaglomerular complex xref: ncithesaurus:Juxtaglomerular_Apparatus ! Juxtaglomerular Apparatus xref: MESH:A05.810.453.736.520.520 ! juxtaglomerular apparatus is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001225 ! cortex of kidney relationship: has_part CL:0000648 ! juxtaglomerular cell relationship: capable_of GO:0003093 {source="GO"} ! regulation of glomerular filtration xref: SCTID:362219002 ! Entire juxtaglomerular apparatus xref: UMLS:C0022445 [Term] id: UBERON:0004738 name: metanephric juxtaglomerular apparatus def: "juxtaglomerular apparatus of the mature vertebrate kidney, or metanephros." [GO:0072206] synonym: "juxtaglomerular apparatus of metanephros" EXACT [] intersection_of: UBERON:0002303 ! juxtaglomerular apparatus intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0010533 {is_inferred="true", source="reference_0000032"} ! metanephros cortex [Term] id: UBERON:0002310 name: hippocampus fimbria def: "A prominent band of white matter along the medial edge of the hippocampus[WP]." [Wikipedia:Fimbria_of_hippocampus] comment: This class was created automatically from a combination of ontologies synonym: "hippocampal fimbria" EXACT [MP:0009324] synonym: "fimbria hippocampus" EXACT [] synonym: "neuraxis fimbria" EXACT [] synonym: "fimbria" EXACT [NIF_GrossAnatomy:birnlex_1502] synonym: "fimbria of the fornix" EXACT [NIF_GrossAnatomy:birnlex_1502] synonym: "fimbria-fornix" EXACT [NIF_GrossAnatomy:birnlex_1502] synonym: "fimbria of hippocampus" EXACT [FMA:83866] xref: FMA:83866 ! Fimbria of hippocampus xref: MA:0000949 ! fimbria hippocampus xref: NIF_GrossAnatomy:birnlex_1502 ! Fimbria of hippocampus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Gray749.png/200px-Gray749.png xref: BM:Tel-FI ! fimbria of hippocampus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001954 {source="MA"} ! hippocampus xref: ncithesaurus:Fimbria ! Fimbria xref: SCTID:369096000 ! Entire fimbria of hippocampus synonym: "fimbria hippocampi" RELATED LATIN [Wikipedia:Fimbria_of_hippocampus] xref: http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray749.png xref: UMLS:C0152315 [Term] id: UBERON:0002305 name: layer of hippocampus def: "the layers of the laminar structure of the hippocampus." [MP:0000813, Wikipedia:Hippocampus_anatomy#Hippocampal_Cells_and_Layers] comment: TODO - check NIF xref synonym: "hippocampus layer" EXACT [] synonym: "cytoarchitectural fields of hippocampal formation" EXACT [NIF_GrossAnatomy:birnlex_1192] xref: FMA:83679 ! Layer of hippocampus xref: MA:0002427 ! hippocampus layer xref: NIF_GrossAnatomy:birnlex_1192 ! Cytoarchitectural fields of hippocampal formation is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001954 ! Ammon's horn [Term] id: UBERON:0007639 name: hippocampus alveus def: "Regional part of fornix consisting of a thin layer of white matter on the surface of the hippocampal formation, bordering the wall of the lateral ventricle and composed of white, myelinated fibers. The alveus arises from cell bodies in the subiculum and hippocampus, and eventually merges with the fimbria of the hippocampus. The fimbria goes on to become the fornix (MM: 2006-10-26)." [NIF_GrossAnatomy:birnlex_1510] comment: todo - check xref: ncithesaurus:Alveus ! Alveus synonym: "alveus" EXACT [NIF_GrossAnatomy:birnlex_1510] synonym: "neuraxis alveus" EXACT [FMA:83867] synonym: "alveus of hippocampus" EXACT [FMA:83867] xref: NIF_GrossAnatomy:birnlex_1510 ! Alveus xref: FMA:83867 ! alveus of hippocampus is_a: UBERON:0002305 {source="Wikipedia"} ! layer of hippocampus xref: SCTID:369094002 ! Entire alveus of hippocampus xref: ncithesaurus:Alveus ! Alveus xref: UMLS:C0228247 [Term] id: UBERON:0005371 name: hippocampus stratum oriens def: "The term Stratum oriens is a cytoarchitectural term denoting the layer of the hippocampus that is deep to the Stratum pyramidale hippocampi and superficial to the alveus (Stephan-75)." [nif_annot:NeuroNames_defSource] synonym: "stratum oriens" EXACT [NIF_GrossAnatomy:birnlex_4113] synonym: "oriens layer of hippocampus" EXACT [NIF_GrossAnatomy:birnlex_4113] synonym: "polymorphic layer of hippocampus" EXACT [NIF_GrossAnatomy:birnlex_4113] synonym: "oriens layer of the hippocampus" EXACT [NIF_GrossAnatomy:birnlex_4113] synonym: "polymorphic layer of the hippocampus" EXACT [NIF_GrossAnatomy:birnlex_4113] xref: MA:0000958 ! hippocampus stratum oriens xref: FMA:83893 ! Oriens layer of hippocampus xref: NIF_GrossAnatomy:birnlex_4113 ! Stratum oriens is_a: UBERON:0002305 ! layer of hippocampus [Term] id: UBERON:0002313 name: hippocampus pyramidal layer alt_id: UBERON:0005369 def: "A cytoarchitectural term denoting the layer of the hippocampus in which pyramidal cells are predominant. Its location is superficial to the Stratum oriens; it is deep to the Stratum radiatum in area CA1 and area CA2 and deep to the Stratum lucidum in area CA3 (Stephan-75) (NeuroNames)." [NIF_GrossAnatomy:birnlex_1444] synonym: "hippocampus stratum pyramidale" RELATED [] synonym: "stratum pyramidale hippocampi" EXACT [NIF_GrossAnatomy:birnlex_1444] synonym: "pyramidal cell layer of the hippocampus" EXACT [NIF_GrossAnatomy:birnlex_1444] synonym: "stratum pyramidale" EXACT [NIF_GrossAnatomy:birnlex_1444] synonym: "pyramidal layer of hippocampus" EXACT [FMA:83895] xref: FMA:83895 ! Pyramidal layer of hippocampus xref: MA:0000956 ! hippocampus pyramidal layer xref: NIF_GrossAnatomy:birnlex_1444 ! Stratum pyramidale hippocampi xref: BTO:0001066 ! hippocampal pyramidal layer is_a: UBERON:0002305 ! layer of hippocampus [Term] id: UBERON:0007637 name: hippocampus stratum lucidum def: "A cytoarchitectural term denoting the layer of the CA3 field of the HIPPOCAMPUS that is deep to the Stratum pyramidale hippocampi and superficial to the Stratum radiatum (Hof-2000)." [nif_annot:NeuroNames_defSource, Wikipedia:Stratum_lucidum_of_hippocampus] synonym: "stratum lucidum" BROAD [NIF_GrossAnatomy:birnlex_4108] xref: NIF_GrossAnatomy:birnlex_4108 ! Stratum lucidum is_a: UBERON:0002305 {source="NIF_GrossAnatomy"} ! layer of hippocampus xref: ncithesaurus:Stratum_Lucidum ! Stratum Lucidum (also: UBERON:0002071 'stratum lucidum of epidermis') synonym: "stratum lucidum hippocampi" RELATED LATIN [Wikipedia:Stratum_lucidum_of_hippocampus] xref: SCTID:419156002 ! Entire stratum lucidum (also: UBERON:0002071 'stratum lucidum of epidermis') xref: UMLS:C0221922 [Term] id: UBERON:0005372 name: hippocampus stratum radiatum def: "The layer located immediately above the pyramidal cell layer in CA2 and CA1 and superficial to the stratum lucidum in CA3. Suprapyramidal region in which CA3 to CA3 associational connections and CA3 to CA1 Schaffer collateral connections are located." [NIF_GrossAnatomy:birnlex_1298] synonym: "stratum radiatum" EXACT [NIF_GrossAnatomy:birnlex_1298] synonym: "radiate layer of hippocampus" EXACT [FMA:83894] xref: MA:0000959 ! hippocampus stratum radiatum xref: FMA:83894 ! Radiate layer of hippocampus xref: NIF_GrossAnatomy:birnlex_1298 ! Stratum radiatum is_a: UBERON:0002305 ! layer of hippocampus [Term] id: UBERON:0007640 ! hippocampus stratum lacunosum moleculare name: hippocampus stratum lacunosum moleculare def: "A cytoarchitectural term denoting the outermost layer of the hippocampus (Stephan-75) (NeuroNames)." [nif_annot:NeuroNames_defSource] synonym: "stratum lacunosum moleculare" EXACT [NIF_GrossAnatomy:birnlex_1359] synonym: "stratum lacunosum-moleculare" EXACT [ABA:ABA] synonym: "lacunar-molecular layer of hippocampus" EXACT [FMA:83149] xref: FMA:83149 ! Lacunar-molecular layer of hippocampus xref: NIF_GrossAnatomy:birnlex_1359 ! Stratum lacunosum moleculare is_a: UBERON:0002305 ! layer of hippocampus [Term] id: UBERON:0005370 name: hippocampus stratum lacunosum comment: Due to its small size, it is often grouped together with stratum moleculare into a single stratum called stratum lacunosum-moleculare[WP] synonym: "lacunar layer of hippocampus" EXACT [] xref: MA:0000957 ! hippocampus stratum lacunosum is_a: UBERON:0002305 ! layer of hippocampus relationship: part_of UBERON:0007640 ! hippocampus stratum lacunosum moleculare [Term] id: UBERON:0005368 name: hippocampus molecular layer def: "A cytoarchitectural region of the hippocampus consisting of a composite of the two outermost layers of the hippocampus, the Stratum lacunosum-moleculare and the Stratum radiatum (Carpenter-83)." [nif_annot:NeuroNames_defSource] synonym: "hippocampus stratum moleculare" RELATED [] synonym: "hippocampal molecular layer" EXACT [NIF_GrossAnatomy:birnlex_1211] synonym: "molecular layer of hippocampus" EXACT [NIF_GrossAnatomy:birnlex_1211] xref: MA:0000955 ! hippocampus molecular layer xref: NIF_GrossAnatomy:birnlex_1211 ! Hippocampal molecular layer is_a: UBERON:0002305 ! layer of hippocampus relationship: part_of UBERON:0007640 ! hippocampus stratum lacunosum moleculare [Term] id: UBERON:0005367 name: hippocampus granule cell layer comment: todo - check xref: MA:0000954 ! hippocampus granule cell layer is_a: UBERON:0002305 ! layer of hippocampus [Term] id: UBERON:0002306 name: nasal mucus def: "In the respiratory system mucus aids in the protection of the lungs by trapping foreign particles that enter it, particularly through the nose, during normal breathing. Phlegm is a specialized term for mucus that is restricted to the respiratory tract, while the term mucus more globally describes secretions of the nasal passages as well." [Wikipedia:Nasal_mucus#Respiratory_system] comment: TODO - split nasal vs respiratory tract? subset: uberon_slim synonym: "respiratory mucus" EXACT [BTO:0003603] xref: FMA:83688 ! Nasal mucus xref: MA:0002535 ! nasal mucus xref: BTO:0003603 ! respiratory mucus xref: ncithesaurus:Nasal_Mucus ! Nasal Mucus intersection_of: UBERON:0000912 ! mucus intersection_of: secreted_by UBERON:0004785 ! respiratory system mucosa xref: UMLS:C0225392 [Term] id: UBERON:0002307 name: choroid plexus of lateral ventricle def: "A choroid plexus that is part of a lateral ventricle [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies subset: vertebrate_core synonym: "chorioid plexus of lateral ventricle" EXACT [] synonym: "lateral ventricle choroid plexus" EXACT [] synonym: "chorioid plexus of cerebral hemisphere of lateral ventricle" EXACT [OBOL:automatic] synonym: "lateral ventricle chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "choroid plexus telencephalic ventricle" EXACT [ZFA:0001447] xref: FMA:83711 ! Choroid plexus of lateral ventricle xref: MA:0000961 ! lateral ventricle choroid plexus xref: ZFA:0001447 ! choroid plexus telencephalic ventricle xref: VHOG:0001376 ! choroid plexus telencephalic ventricle is_a: UBERON:0001886 ! choroid plexus of cerebral hemisphere intersection_of: UBERON:0001886 ! choroid plexus of cerebral hemisphere intersection_of: part_of UBERON:0002285 ! lateral ventricle relationship: part_of UBERON:0002285 ! lateral ventricle xref: ncithesaurus:Choroid_Plexus_of_the_Lateral_Ventricle ! Choroid Plexus of the Lateral Ventricle xref: SCTID:70064002 ! Entire choroid plexus of lateral ventricle xref: EHDAA2:0004449 ! lateral ventricle choroid plexus xref: TAO:0001447 ! choroid plexus telencephalic ventricle xref: UMLS:C0152289 [Term] id: UBERON:0002309 name: medial longitudinal fasciculus def: "The medial longitudinal fasciculus (MLF) is a pair of crossed fiber tracts, one on each side of the brainstem. These bundles of axons are situated near the midline of the brainstem and are composed of both ascending and descending fibers that arise from a number of sources and terminate in different areas. [WP,unvetted]." [Wikipedia:Medial_longitudinal_fasciculus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "MLF" RELATED [ZFA:0000543] xref: FMA:83846 ! Medial longitudinal fasciculus xref: TAO:0000543 ! medial longitudinal fasciculus xref: ZFA:0000543 ! medial longitudinal fasciculus xref: BTO:0003951 ! medial longitudinal fasciculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/26/Gray711.png/200px-Gray711.png is_a: UBERON:0005838 ! fasciculus of brain xref: SCTID:362397001 ! Entire medial longitudinal fasciculus synonym: "fasciculus longitudinalis medialis" RELATED LATIN [Wikipedia:Medial_longitudinal_fasciculus] xref: http://upload.wikimedia.org/wikipedia/commons/2/26/Gray711.png [Term] id: UBERON:0005159 name: pyramid of medulla oblongata def: "The anterior or ventral portion of the medulla oblongata is named the pyramid and lies between the anterior median fissure and the antero-lateral sulcus. Its upper end is slightly constricted, and between it and the pons the fibers of the abducent nerve emerge; a little below the pons it becomes enlarged and prominent, and finally tapers into the anterior funiculus of the medulla spinalis, with which, at first sight, it appears to be directly continuous[WP]." [Wikipedia:Pyramid_(brainstem)] synonym: "lobule VIII of Larsell" EXACT [FMA:75254] synonym: "medullary pyramid" EXACT [FMA:75254] synonym: "pyramid of medulla oblongata" EXACT [Wikipedia:Pyramid_(brainstem)] synonym: "pyramid of medulla" EXACT [FMA:75254] xref: FMA:75254 ! pyramid of medulla xref: BM:Me-Py ! pyramid is_a: UBERON:0002678 ! regional part of medulla oblongata disjoint_from: UBERON:0004200 ! kidney pyramid relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:9535007 ! Pyramid of medulla oblongata [Term] id: UBERON:0002315 name: gray matter of spinal cord def: "the ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue." [MP:0008503] synonym: "grey matter of spinal cord" EXACT [] synonym: "grey substance of spinal cord" EXACT [] synonym: "spinal cord grey matter" EXACT [] synonym: "gray matter of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "spinal cord gray matter" EXACT [OBOL:automatic] synonym: "spinal cord gray matter of neuraxis" EXACT [OBOL:automatic] synonym: "spinal cord grey substance" EXACT [OBOL:automatic] xref: FMA:256580 ! Gray matter of spinal cord xref: MA:0000002 ! spinal cord grey matter xref: NIF_GrossAnatomy:nlx_anat_100204 ! Spinal cord grey matter is_a: UBERON:0002020 ! gray matter of neuraxis intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord xref: ncithesaurus:Gray_Matter_of_the_Spinal_Cord ! Gray Matter of the Spinal Cord xref: SCTID:279441003 ! Entire spinal cord gray matter synonym: "gray substance of spinal cord" EXACT [FMA:256580] xref: UMLS:C0475853 [Term] id: UBERON:0002316 name: white matter def: "Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system." [UBERON:cjm, Wikipedia:White_matter] subset: uberon_slim subset: vertebrate_core synonym: "white substance" EXACT [] synonym: "white matter of neuraxis" EXACT [FMA:83929] synonym: "neuronal white matter" EXACT [AEO:0001011] xref: FMA:83929 ! White matter of neuraxis xref: MA:0001135 ! white matter xref: ZFA:0001682 ! white matter xref: ncithesaurus:White_Matter ! White Matter xref: OpenCyc:Mx4rwOAsDZwpEbGdrcN5Y29ycA ! white matter xref: AEO:0000139 ! white matter xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/Spinal_nerve.svg/200px-Spinal_nerve.svg.png xref: NIF_GrossAnatomy:Class_2 ! White matter xref: AEO:0001011 ! neuronal white matter is_a: UBERON:0003714 {source="AEO"} ! neural tissue is_a: UBERON:0011215 {source="FMA"} ! cell part cluster of neuraxis relationship: part_of UBERON:0001017 ! central nervous system relationship: has_part UBERON:0006135 ! myelinated nerve fiber relationship: has_part GO:0043209 ! myelin sheath relationship: has_part GO:0030424 ! axon xref: TAO:0000145 ! CNS tracts and commissures xref: TAO:0002142 ! white matter xref: TAO:0002143 ! CNS white matter synonym: "substantia alba" RELATED LATIN [Wikipedia:White_matter] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Grey_matter_and_white_matter_-_very_high_mag.jpg xref: VHOG:0001764 ! white matter property_value: external_definition "Multi-tissue structure comprised largely of myelinated axons.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002142", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "white mater" RELATED [VHOG:0001764] synonym: "CNS tracts and commissures" RELATED [TAO:0000145] synonym: "CNS white matter" RELATED [TAO:0002143] property_value: homology_notes "The myelination of axons by glial cells was the last major step in the evolution of cells in the vertebrate nervous system, and white-matter tracts are key to the architecture of the mammalian brain.[well established][VHOG]" xsd:string {external_class="VHOG:0001764", ontology="VHOG", source="DOI:10.1038/nature09614 Nave KA\, Myelination and support of axonal integrity by glia. Nature (2010)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: external_definition "Cell part cluster consisting predominantly of neurites in the brain and the spinal cord[FMA:83929]." xsd:string {source="FMA:83929"} xref: UMLS:C0682708 [Term] id: UBERON:0002317 name: white matter of cerebellum comment: note that in NIF this is a composite structure; in MA and FMA it is explicitly part of cerebellum. This leads to consistency problems with strict parcellation schemes like ABA, see cerebellar peduncles. In NIF this is a composite structure, this is followed partially here in weakening the relationship to overlaps subset: vertebrate_core synonym: "cerebellum white matter" EXACT [] synonym: "cerebellar white matter" EXACT [] xref: FMA:83943 ! White matter of cerebellum xref: MA:0002430 ! cerebellum white matter xref: ncithesaurus:Cerebellum_White_Matter ! Cerebellum White Matter xref: ZFA:0001708 ! cerebellar white matter xref: NIF_GrossAnatomy:birnlex_1562 ! Cerebellar white matter is_a: UBERON:0002316 ! white matter of neuraxis relationship: overlaps UBERON:0002037 {source="FMA-weakened",source="MA-weakened"} ! cerebellum xref: SCTID:362412009 ! Entire cerebellar white matter xref: TAO:0002183 ! cerebellar white matter property_value: external_definition "CNS white matter that is part of the cerebellum.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002183", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0152381 [Term] id: UBERON:0002319 name: mesangium def: "inner layer of the glomerulus, within the basement membrane surrounding the glomerular capillaries." [Wikipedia:Mesangium, http://sourceforge.net/tracker/?group_id=76834&atid=974957] comment: WP considers this the same as glomerular mesangium. In MA, glomerular and extraglomerular are distingsuished. subset: uberon_slim xref: FMA:84139 ! Mesangium xref: MA:0002617 ! mesangium xref: ncithesaurus:Mesangium ! Mesangium xref: BTO:0002494 ! mesangium xref: EMAPA:28248 ! glomerular mesangium of glomerular tuft (also: UBERON:0002320 'glomerular mesangium') xref: MESH:A05.810.453.736.520.380 ! glomerular mesangium (also: UBERON:0002320 'glomerular mesangium') is_a: UBERON:0003891 ! stroma relationship: part_of UBERON:0000074 ! renal glomerulus relationship: part_of UBERON:0005215 ! kidney interstitium property_value: has_relational_adjective "mesangial" xsd:string xref: UMLS:C0017655 [Term] id: UBERON:0002320 name: glomerular mesangium def: "A thin membrane which helps to support the capillary loops in a renal glomerulus. It is connective tissue composed of mesangial cells - myofibroblasts phenotypically related to vascular smooth muscle cells (MUSCLE, SMOOTH, VASCULAR), PHAGOCYTES and the mesangial EXTRACELLULAR MATRIX." [Wikipedia:Glomerular_mesangium, MESH:A05.810.453.736.520.380] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:84140 ! Glomerular mesangium xref: GAID:430 ! glomerular mesangium xref: MA:0002606 ! glomerular mesangium xref: EMAPA:27961 ! glomerular mesangium of maturing glomerular tuft xref: EMAPA:28248 ! glomerular mesangium of glomerular tuft (also: UBERON:0002319 'mesangium') xref: MESH:A05.810.453.736.520.380 ! glomerular mesangium (also: UBERON:0002319 'mesangium') is_a: UBERON:0003891 ! stroma relationship: part_of UBERON:0002319 ! mesangium relationship: part_of UBERON:0004190 {source="GO"} ! glomerulus vasculature xref: SCTID:244574009 ! Entire glomerular mesangium [Term] id: UBERON:0002321 name: extraglomerular mesangium comment: editor note - check MA part_ofs - should be spatially disjoint from renal glomerulus? xref: FMA:84141 ! Extraglomerular mesangium xref: MA:0002602 ! extraglomerular mesangium xref: EMAPA:28278 ! extraglomerular mesangium is_a: UBERON:0003891 ! stroma relationship: part_of UBERON:0001229 {source="MA"} ! renal corpuscle relationship: part_of UBERON:0002303 {source="MA"} ! juxtaglomerular apparatus relationship: part_of UBERON:0002319 {source="MA"} ! mesangium relationship: overlaps UBERON:0000074 ! renal glomerulus [Term] id: UBERON:0012352 name: mesangial matrix def: "Extracellular matrix secreted by intraglomerular mesangial cells" [MP:0011338] synonym: "extracellular mesangial matrix" EXACT [MP:0011338] is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0002319 ! mesangium relationship: secreted_by UBERON:0002320 ! glomerular mesangium relationship: composed_primarily_of GO:0031012 ! extracellular matrix [Term] id: UBERON:0002322 name: periventricular nucleus def: "." [Wikipedia:Periventricular_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "ventral zone of periventricular hypothalamus" EXACT [ZFA:0000260] xref: FMA:84354 ! Periventricular nucleus xref: TAO:0000260 ! periventricular nucleus xref: ZFA:0000260 ! periventricular nucleus is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002324 name: muscle of back def: "A muscle organ that is part of a back [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "back muscle" EXACT [] synonym: "back muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of back" EXACT [OBOL:automatic] xref: FMA:85216 ! Muscle of back xref: MA:0000496 ! back muscle is_a: UBERON:0001774 ! muscle of trunk intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0002325 name: epithelium of urethra def: "The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.." [GO:0061071] comment: This class was created automatically from a combination of ontologies synonym: "urethra epithelium" EXACT [] synonym: "urethral epithelium" RELATED [] synonym: "epithelial tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra epithelial tissue" EXACT [OBOL:automatic] xref: FMA:85275 ! Epithelium of urethra xref: MA:0001686 ! urethra epithelium xref: ncithesaurus:Urethra_Epithelium ! Urethra Epithelium is_a: UBERON:0003914 {source="GO"} ! epithelial tube is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000057 ! urethra xref: UMLS:C1710584 [Term] id: UBERON:0002326 name: lamina propria of urethra def: "A lamina propria that is part of a urethra [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "urethra lamina propria" EXACT [] synonym: "urethral lamina propria" RELATED [] synonym: "lamina propria mucosa of urethra" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of urethra" EXACT [OBOL:automatic] synonym: "urethra lamina propria mucosa" EXACT [OBOL:automatic] synonym: "urethra lamina propria mucosae" EXACT [OBOL:automatic] xref: FMA:85276 ! Lamina propria of urethra xref: MA:0001689 ! urethra lamina propria is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0001008 ! urinary system [Term] id: UBERON:0002327 name: trunk of intercostal nerve comment: This class was created automatically from a combination of ontologies synonym: "intercostal nerve trunk" EXACT [] synonym: "intercostal neural trunk" EXACT [] xref: FMA:85315 ! Trunk of intercostal nerve xref: MA:0001176 ! intercostal nerve trunk is_a: UBERON:0001147 ! trunk of peripheral nerve [Term] id: UBERON:0002328 name: notochord def: "a flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube." [ISBN:0815318960, Wikipedia:Notochord, http://tolweb.org/Chordata/2499, http://purl.obolibrary.org/obo/uberon/tracker/25] comment: Development notes: In between vertebra the notochord becomes the nucleus pulposus, under it degenerates, and at anterior end in some species its tissue merges with some of the cranial bones.. Some organisms retain a post-embryonic notochord. // The notochord appears early in embryogeny and plays an important role in promoting or organizing the embryonic development of nearby structures. In most adult chordates the notochord disappears or becomes highly modified. In some non-vertebrate chordates and fishes the notochord persists as a laterally flexible but incompressible skeletal rod that prevents telescopic collapse of the body during swimming[TOLWEB] subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 ! notochord xref: EHDAA:1241 ! notochord xref: EHDAA:6021 ! notochord xref: FMA:85521 ! Notochord xref: GAID:1311 ! notochord xref: VHOG:0000199 ! notochord xref: MAT:0000281 ! notochord xref: TAO:0000135 ! notochord xref: XAO:0000055 ! notochord xref: ZFA:0000135 ! notochord xref: ncithesaurus:Notochord ! Notochord xref: BTO:0001768 ! notochord xref: EHDAA2:0001277 ! notochord xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png xref: EMAPA:16191 ! notochord xref: MESH:A16.254.610 ! notochord xref: EV:0100002 ! notochord xref: VSAO:0000032 ! notochord is_a: UBERON:0000481 {source="VSAO"} ! multi-tissue structure relationship: existence_starts_during UBERON:0000068 ! embryo stage relationship: develops_from UBERON:0004880 {source="ZFA"} ! chordamesoderm relationship: develops_from UBERON:0006267 {source="EHDAA2"} ! notochordal plate relationship: dorsal_to UBERON:0001049 ! neural tube relationship: ventral_to UBERON:0001555 ! digestive tract relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata relationship: part_of UBERON:0011137 ! axial skeletal system relationship: part_of UBERON:0000922 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! embryo relationship: secretes PR:000014841 ! sonic hedgehog protein xref: SCTID:308820002 ! Entire notochord synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png xref: http://evolution.berkeley.edu/evolibrary/images/history/notochords.jpg property_value: external_definition "Slender rod of fibrous connective tissue surrounding a core of fluid-filled cells of mesodermal origin; it lies above the gut and directly beneath the spinal cord. The notochord is present during early development and in a few cases it is retained through life; however, usually the notochord is replaced by the vertebral column.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000327", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship type change: differentiates_from mesoderm (AAO:0000304) CHANGED TO: develops_from mesoderm (UBERON:0000926)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000327", date_retrieved="2012-06-20"} property_value: external_definition "Rod-like principal supportive element of the embryo and larva, present in the midline just ventral to the neural tube, and differentiating during the segmentation period to form large vacuolated epithelial cells and a surrounding a sheath of fibrous and elastic layers. Layering of the sheath may differ in structure, thickness and development among groups; in cypriniforms there are actually three very thin layers to the sheath. A functional, well developed notochord is present throughout life in certain basal fish groups but not in cypriniforms. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000135", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Avascular multi-tissue structure composed of large vacuolated epithelial cells (chordablasts) and perichordal fibrous tissue.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000032", date_retrieved="2012-08-14", source="PSPUB:0000170"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (3) a stiff, longitudinal rod of turgid cells along the dorsal part of the body that is called a notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000199", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "notochordal" xsd:string xref: UMLS:C0028439 [Term] id: UBERON:0006267 name: notochordal plate subset: emapa_ehdaa2 def: "The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord." [VHOG:0001212] comment: TODO - check ordering; awaiting confirmation from JB xref: EMAPA:16101 ! notochordal plate xref: EHDAA2:0001278 ! notochordal plate xref: VHOG:0001212 ! notochordal plate xref: EHDAA:264 ! notochordal plate is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0006268 {source="EHDAA2"} ! notochordal process xref: ncithesaurus:Notochordal_Plate ! Notochordal Plate property_value: external_definition "The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001212", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C1518429 [Term] id: UBERON:0006268 name: notochordal process def: "a midline cellular cord formed from the migration of mesenchymal cells from the primitive knot" [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/05embryonicperiod.htm] comment: The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. subset: emapa_ehdaa2 synonym: "chordamesoderm" RELATED [] synonym: "presumptive notochord" RELATED [] xref: EMAPA:16102 ! notochordal process xref: EHDAA2:0001279 ! notochordal process xref: VHOG:0001213 ! notochordal process xref: EHDAA:224 ! notochordal process is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0000924 {source="EHDAA2"} ! ectoderm xref: ncithesaurus:Notochordal_Process ! Notochordal Process xref: UMLS:C1518430 [Term] id: UBERON:0003068 name: axial mesoderm def: "The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GO:0048318, Wikipedia:Chordamesoderm] subset: uberon_slim synonym: "chordamesoderm" RELATED [Wikipedia:Chordamesoderm] xref: VHOG:0000107 ! axial mesoderm xref: TAO:0001204 ! axial mesoderm xref: XAO:0000205 ! axial mesoderm xref: ZFA:0001204 ! axial mesoderm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png xref: EFO:0003647 ! axial mesoderm is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0000926 ! mesoderm relationship: part_of UBERON:0000926 ! mesoderm xref: AAO:0011017 ! axial mesoderm xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png property_value: external_definition "The portion of the mesoderm underlying the midline of the embryo. [Gastrulation:_From_cells_to_embryo_(2004)_Cold_Spring_Harbor, Glossary_XV, New_York:_Cold_Spring_Harbor_Laboratory_Press, Stern_CD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000107", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004880 ! chordamesoderm name: chordamesoderm def: "The central region of trunk mesoderm. This tissue forms the notochord" [UBERON:cjm] comment: note that WP treats this as synonym of axial mesoderm. Induces neural tube. Gilbert: contains an anterior head process and the notochord. synonym: "axial chorda mesoderm" EXACT [ZFA:0000091] synonym: "presumptive notochord" EXACT [ZFA:0000091] synonym: "chorda mesoderm" EXACT [] synonym: "dorsal mesoderm" EXACT [UBERONREF:0000002] xref: ZFA:0000091 ! axial chorda mesoderm xref: AAO:0000478 ! presumptive notochord xref: EFO:0003426 ! axial chorda mesoderm is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003068 ! axial mesoderm xref: TAO:0000091 ! axial chorda mesoderm property_value: external_definition "Notochord rudiment[ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"} [Term] id: UBERON:0011288 name: stomochord def: "A flexible, hollow tube that arises in embryonic development as an outpocketing from the roof of the embryonic gut anterior to the pharynx. In adults, they extend dorsally from the pharynx into the probiscis, and serve to communicate with the oral cavity. Their walls are composed primarily of epithelial cells, but ciliated and glandular cells are also present" [Wikipedia:Stomochord] synonym: "stomatochord" RELATED [] is_a: UBERON:0000481 ! multi-tissue structure relationship: only_in_taxon NCBITaxon:10219 ! Hemichordata relationship: existence_starts_during UBERON:0000068 ! embryo stage relationship: develops_from UBERON:0007026 ! primitive gut [Term] id: UBERON:0002330 name: exocrine system def: "Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]." [Wikipedia:Exocrine_gland] subset: uberon_slim synonym: "exocrine glandular system" EXACT [EHDAA2:0002225] xref: FMA:85539 ! Exocrine system xref: MA:0002411 ! exocrine system xref: EHDAA2:0002225 ! exocrine glandular system xref: ncithesaurus:Exocrine_System ! Exocrine System xref: WikipediaCategory:Exocrine_system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system xref: UMLS:C1516995 [Term] id: UBERON:0002333 ! pulmonary trunk name: pulmonary trunk def: "Pulmonary arterial trunk which is continuous with the right ventricle.[FMA]" [Wikipedia:Pulmonary_artery, FMA:FMA] subset: uberon_slim subset: vessel_or_tree synonym: "pulmonary artery (trunk)" EXACT [] synonym: "trunk of pulmonary arterial tree" EXACT [] xref: FMA:8612 ! Pulmonary trunk xref: VHOG:0001134 ! pulmonary trunk xref: MA:0002033 ! pulmonary trunk xref: OpenCyc:Mx4rv-6d0ZwpEbGdrcN5Y29ycA xref: EFO:0001399 ! pulmonary artery (also: UBERON:0002012 'pulmonary artery') xref: EHDAA:9831 ! pulmonary trunk xref: galen:PulmonaryTrunk ! pulmonary trunk xref: OpenCyc:Mx4rv-6d0ZwpEbGdrcN5Y29ycA ! pulmonary trunk xref: EHDAA2:0001576 ! pulmonary trunk xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Alveoli_diagram.png/200px-Alveoli_diagram.png xref: EMAPA:17015 ! pulmonary trunk of aortico-pulmonary spiral septum xref: EMAPA:18240 ! pulmonary trunk of arterial system of cardiovascular system of organ system is_a: UBERON:0001637 {source="MA"} ! artery relationship: part_of UBERON:0001009 ! circulatory system relationship: continuous_with UBERON:0002080 ! right ventricle xref: http://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png property_value: external_definition "An arterial trunk with origin from the right ventricle of the heart, and dividing into the right and left pulmonary arteries, which enter the corresponding lungs and branch with the bronchi. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001134", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/pulmonary+trunk", source="http://bgee.unil.ch/"} property_value: homology_notes "As in birds, the conus arteriosus split during embryonic development in mammals to produce the pulmonary trunk and single aortic trunk of the adult.[well established][VHOG]" xsd:string {external_class="VHOG:0001134", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.481", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002337 name: endometrial stroma comment: This class was created automatically from a combination of ontologies synonym: "endometrium stroma" EXACT [] synonym: "stroma of endometrium" EXACT [] xref: FMA:86487 ! Endometrial stroma xref: MA:0002734 ! endometrium stroma xref: ncithesaurus:Endometrial_Stroma ! Endometrial Stroma is_a: UBERON:0003891 ! stroma relationship: part_of UBERON:0001295 ! endometrium xref: SCTID:254115004 ! Entire endometrial stroma xref: UMLS:C0227849 [Term] id: UBERON:0002338 name: lamina propria of bronchus def: "A lamina propria that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "bronchus lamina propria" EXACT [] synonym: "bronchi lamina propria" EXACT [OBOL:automatic] synonym: "bronchi lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bronchi lamina propria mucosae" EXACT [OBOL:automatic] synonym: "bronchial trunk lamina propria" EXACT [OBOL:automatic] synonym: "bronchial trunk lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bronchial trunk lamina propria mucosae" EXACT [OBOL:automatic] synonym: "bronchus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bronchus lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bronchi" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bronchus" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bronchi" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bronchial trunk" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bronchus" EXACT [OBOL:automatic] synonym: "lamina propria of bronchi" EXACT [OBOL:automatic] synonym: "lamina propria of bronchial trunk" EXACT [OBOL:automatic] xref: FMA:86619 ! Lamina propria of bronchus xref: MA:0001836 ! bronchus lamina propria xref: ncithesaurus:Bronchus_Lamina_Propria ! Bronchus Lamina Propria is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0000410 {is_inferred="true", source="reference_0000032"} ! bronchial mucosa xref: UMLS:C1707054 [Term] id: UBERON:0002339 name: epithelium of lobar bronchus def: "the tissue made up of epithelial cells that lines the inside of the lobar bronchus." [GO:0060481] synonym: "lobar bronchial epithelium" EXACT [] synonym: "lobar bronchus epithelium" EXACT [] synonym: "epithelial tissue of lobar bronchus" EXACT [OBOL:automatic] synonym: "epithelial tissue of secondary bronchus" EXACT [OBOL:automatic] synonym: "epithelium of secondary bronchus" EXACT [OBOL:automatic] synonym: "lobar bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "secondary bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "secondary bronchus epithelium" EXACT [OBOL:automatic] xref: FMA:86624 ! Epithelium of lobar bronchus xref: MA:0001842 ! lobar bronchus epithelium xref: EMAPA:17390 ! epithelium of lobar bronchus of left lung rudiment xref: EMAPA:17658 ! epithelium of lobar bronchus of left lung xref: EMAPA:17666 ! epithelium of lobar bronchus of right lung xref: EMAPA:17984 ! epithelium of lobar bronchus of accessory lobe xref: EMAPA:17989 ! epithelium of lobar bronchus of caudal lobe xref: EMAPA:17994 ! epithelium of lobar bronchus of cranial lobe xref: EMAPA:18000 ! epithelium of lobar bronchus of middle lobe intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002183 ! lobar bronchus [Term] id: UBERON:0002340 name: epithelium of main bronchus alt_id: UBERON:0003245 def: "An epithelium that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "main bronchial epithelium" EXACT [] synonym: "main bronchus epithelium" EXACT [] synonym: "bronchus principalis epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchus principalis epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of bronchus principalis" EXACT [OBOL:automatic] synonym: "epithelial tissue of main bronchus" EXACT [OBOL:automatic] synonym: "epithelial tissue of primary bronchus" EXACT [OBOL:automatic] synonym: "epithelial tissue of principal bronchus" EXACT [OBOL:automatic] synonym: "epithelium of bronchus principalis" EXACT [OBOL:automatic] synonym: "epithelium of primary bronchus" EXACT [OBOL:automatic] synonym: "epithelium of principal bronchus" EXACT [OBOL:automatic] synonym: "main bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "primary bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "primary bronchus epithelium" EXACT [OBOL:automatic] synonym: "principal bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "principal bronchus epithelium" EXACT [OBOL:automatic] xref: FMA:86625 ! Epithelium of main bronchus xref: VHOG:0001034 ! main bronchus epithelium xref: MA:0001847 ! main bronchus epithelium xref: EHDAA:5003 ! epithelium xref: EHDAA2:0001047 ! main bronchus epithelium xref: EMAPA:16851 ! epithelium of main bronchus is_a: UBERON:0002031 ! epithelium of bronchus intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002182 ! main bronchus relationship: part_of UBERON:0002182 ! main bronchus [Term] id: UBERON:0002341 name: epithelium of segmental bronchus def: "An epithelium that is part of a segmental bronchus [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "segmental bronchial epithelium" EXACT [] synonym: "segmental bronchus epithelium" EXACT [] synonym: "epithelial tissue of segmental bronchus" EXACT [OBOL:automatic] synonym: "epithelial tissue of tertiary bronchus" EXACT [OBOL:automatic] synonym: "epithelium of tertiary bronchus" EXACT [OBOL:automatic] synonym: "segmental bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "tertiary bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "tertiary bronchus epithelium" EXACT [OBOL:automatic] xref: FMA:86626 ! Epithelium of segmental bronchus xref: MA:0001850 ! segmental bronchus epithelium is_a: UBERON:0002031 ! epithelium of bronchus intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002184 ! segmental bronchus relationship: part_of UBERON:0002184 ! segmental bronchus [Term] id: UBERON:0002345 name: descending thoracic aorta def: "the part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." [MP:0009868] comment: This class was created automatically from a combination of ontologies xref: FMA:87217 ! Descending thoracic aorta xref: MA:0002572 ! descending thoracic aorta xref: EFO:0002527 ! descending thoracic aorta xref: EMAPA:18605 ! descending (also: UBERON:0001514 'descending aorta') is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001514 ! descending aorta relationship: part_of UBERON:0001515 ! thoracic aorta xref: SCTID:181301002 ! Entire descending thoracic aorta [Term] id: UBERON:0002348 name: epicardium def: "Region of visceral serous pericardium which has as its part, the mesothelium, subepicardial layer of epicardium and the fibroelastic connective tissue that is attached to the myocardium and is continuous with the parietal serous pericardium[FMA]. External layer of the heart[ZFA]." [Wikipedia:Epicardium, ZFIN:curator] comment: TODO - check links with UBERON:0002425 visceral serous pericardium. develops from proepicardium. WP:Epicardium -- When considered as a part of the pericardium, it is the inner layer, or visceral pericardium, continuous with the serous layer. subset: uberon_slim subset: vertebrate_core synonym: "heart epicardium" EXACT [] synonym: "visceral serous pericardium of heart" EXACT [] synonym: "visceral serous pericardium proper" EXACT [FMA:9461] xref: FMA:9461 ! Epicardium xref: galen:Epicardium xref: TAO:0005057 ! epicardium xref: XAO:0000316 ! epicardium xref: AAO:0010409 ! epicardium xref: ZFA:0005057 ! epicardium xref: ncithesaurus:Epicardium ! Epicardium xref: VHOG:0000119 ! heart epicardium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray968.png/200px-Gray968.png is_a: UBERON:0000064 ! organ part relationship: develops_from UBERON:0004160 ! proepicardium relationship: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0002425 ! visceral serous pericardium xref: AAO:0010409 ! epicardium xref: EHDAA2:0002202 ! epicardium synonym: "lamina visceralis pericardii serosi" RELATED LATIN [Wikipedia:Epicardium] xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray968.png property_value: external_definition "The inner layer of the pericardium that is in contact with the surface of the heart.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010409", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "External layer of the heart.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005057", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0225968 [Term] id: UBERON:0002425 name: visceral serous pericardium def: "Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]." [Wikipedia:Visceral_pericardium] subset: uberon_slim synonym: "epicardium" RELATED [MA:0000484] synonym: "visceral lamina of serous pericardium" EXACT [] synonym: "visceral layer of serous pericardium" EXACT [] synonym: "visceral pericardium" EXACT [] synonym: "serous visceral pericardium" EXACT [] synonym: "lamina visceralis pericardii serosi" RELATED LATIN [Wikipedia:Epicardium] xref: FMA:84882 ! Visceral serous pericardium xref: VHOG:0000538 ! visceral pericardium xref: MA:0000484 ! visceral serous pericardium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray968.png/200px-Gray968.png xref: EMAPA:17176 ! visceral pericardium xref: EMAPA:19032 ! visceral of serosal pericardium is_a: UBERON:0002357 ! serous pericardium relationship: attaches_to UBERON:0002349 ! myocardium xref: SCTID:243955001 ! Entire visceral pericardium [Term] id: UBERON:0010131 name: conducting tissue of heart synonym: "specialized conducting tissue of heart" EXACT [FMA:83378] synonym: "specialized muscle tissue of heart" EXACT [FMA:83378] is_a: UBERON:0001133 {source="FMA"} ! cardiac muscle tissue xref: FMA:83378 ! conducting tissue of heart xref: EHDAA2:0004528 ! conducting muscle tissue [Term] id: UBERON:0002350 name: conducting system of heart def: "The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]" [GO:0003161] comment: Editor notes: EHDAA2 divides the system from the tissue subset: vertebrate_core synonym: "cardiac conduction system" EXACT [] synonym: "cardionector" EXACT [] synonym: "central conduction system" RELATED [] synonym: "impulse conducting system" EXACT [MA:0000094] synonym: "cardiac impulse conducting system" EXACT [GO:0003161] synonym: "heart conduction system" EXACT [GO:0003161] xref: FMA:9476 ! Conducting system of heart xref: VHOG:0001271 ! cardiac conducting system xref: TAO:0005063 ! cardiac conduction system xref: ZFA:0005063 ! cardiac conduction system xref: MESH:A07.541.409 ! heart conduction system xref: EV:0100025 ! cardiac conducting system xref: EFO:0003909 ! heart conduction system xref: MA:0000094 ! impulse conducting system is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart relationship: part_of UBERON:0002349 {source="FMA"} ! myocardium relationship: has_part CL:0002068 {source="FMA"} ! Purkinje myocyte relationship: has_part CL:0002073 {source="FMA"} ! transitional myocyte relationship: has_part CL:0002074 {source="FMA"} ! myocardial endocrine cell relationship: has_part CL:1000409 {source="FMA"} ! myocyte of sinuatrial node relationship: has_part CL:1000410 {source="FMA"} ! myocyte of atrioventricular node xref: SCTID:281489000 ! Entire cardiac conducting system xref: EHDAA2:0004185 ! heart muscle conducting system synonym: "cardiac conducting system" EXACT [VHOG:0001271] property_value: homology_notes "The fish heart displays clear polarity of contraction in a posterior-to-anterior direction. The contraction waves originate in the sinus venosus and terminate in the conus arteriosus. The nodal phenotype persists in the inflow region of the heart, varying from the venosinus to the sinoatrial junctional areas in different species . Similar to the mammalian situation, pacemaker tissue with a lower intrinsic rhythmicity is also found at the atrioventricular junction.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001271", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM\, Christoffels VM\, Cardiac Chamber Formation: Development\, Genes\, and Evolution. Physiological Reviews (2003)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002351 name: sinoatrial node def: "The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]." [Wikipedia:Sinoatrial_node, GO:0003163] comment: WP:Heart states: "The SA node is found in all amniotes but not in more primitive vertebrates. In these animals, the muscles of the heart are relatively continuous and the sinus venosus coordinates the beat which passes in a wave through the remaining chambers. Indeed, since the sinus venosus is incorporated into the right atrium in amniotes, it is likely homologous with the SA node. In teleosts, with their vestigial sinus venosus, the main centre of coordination is, instead, in the atrium.". Note however that ZFA has SA node. subset: uberon_slim subset: vertebrate_core synonym: "cardiac pacemaker" EXACT [FMA:9477] synonym: "Koch's node" EXACT [FMA:9477] synonym: "node of Keith-Flack" EXACT [FMA:9477] synonym: "SA nodal muscle tissue" EXACT [FMA:9477] synonym: "SA node" EXACT [FMA:9477] synonym: "sinoatrial node" EXACT [FMA:9477] synonym: "sinu-atrial node" EXACT [FMA:9477] synonym: "sinuatrial nodal muscle tissue" EXACT [FMA:9477] synonym: "sinus node" EXACT [FMA:9477] synonym: "sinus node of Keith and Flack" EXACT [FMA:9477] synonym: "sinuatrial node" EXACT [FMA:9477] synonym: "nodus sinuatrialis" EXACT LATIN [FMA:TA, FMA:9477] xref: FMA:9477 ! Sinuatrial node xref: GAID:561 ! sinoatrial node xref: MA:0000097 ! sinoatrial node xref: OpenCyc:Mx4rOhejDGMcEd2AAABQjYGu0g xref: TAO:0005069 ! sinoatrial node xref: ZFA:0005069 ! sinoatrial node xref: ncithesaurus:Sinoatrial_Node ! Sinoatrial Node xref: OpenCyc:Mx4rOhejDGMcEd2AAABQjYGu0g ! sinoatrial node xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/Sinoatrial_node_low_mag.jpg/200px-Sinoatrial_node_low_mag.jpg xref: BTO:0004358 ! sinus node xref: MESH:A07.541.409.819 ! sinoatrial node xref: EHDAA2:0004184 ! sinoatrial node is_a: UBERON:0001133 ! cardiac muscle tissue relationship: part_of UBERON:0002350 {source="ZFA"} ! conducting system of heart relationship: has_function_in GO:0060048 ! cardiac muscle contraction relationship: capable_of GO:0002027 ! regulation of heart rate xref: SCTID:277687007 ! Entire sinoatrial node synonym: "nodus sinuatrialis" RELATED LATIN [Wikipedia:Sinoatrial_node] xref: http://upload.wikimedia.org/wikipedia/commons/d/de/Sinoatrial_node_2_low_mag.jpg xref: UMLS:C0037189 [Term] id: UBERON:0002352 name: atrioventricular node def: "Subdivision of conducting system of heart which is located in the muscular part of the interatrial septum that is continuous with the atrioventricular bundle.[FMA]" [Wikipedia:Atrioventricular_node, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "aschoff-tawara node" EXACT [] synonym: "atrioventricular nodal muscle tissue" EXACT [] synonym: "av nodal muscle tissue" EXACT [] synonym: "av node" EXACT [] synonym: "node of tawara" EXACT [] xref: EFO:0000276 ! atrioventricular node xref: FMA:9478 ! Atrioventricular node xref: GAID:558 ! atrioventricular node xref: VHOG:0001474 ! atrioventricular node xref: MA:0000095 ! atrioventricular node xref: MAT:0000498 ! atrioventricular node xref: OpenCyc:Mx4rMfD91mMcEd2AAABQjYGu0g xref: TAO:0005070 ! atriovetricular node xref: ZFA:0005070 ! atrioventricular node xref: ncithesaurus:Atrioventricular_Node ! Atrioventricular Node xref: OpenCyc:Mx4rMfD91mMcEd2AAABQjYGu0g ! atrioventricular node xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/92/Gray501.png/200px-Gray501.png xref: MESH:A07.541.409.147 ! atrioventricular node is_a: UBERON:0001133 ! cardiac muscle tissue relationship: part_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002350 ! conducting system of heart xref: SCTID:277688002 ! Entire atrioventricular node xref: EHDAA2:0004183 ! atrioventricular node synonym: "nodus atrioventricularis" RELATED LATIN [Wikipedia:Atrioventricular_node] xref: http://upload.wikimedia.org/wikipedia/commons/5/50/ConductionsystemoftheheartwithouttheHeart.png synonym: "atriovetricular node" RELATED [TAO:0005070] property_value: homology_notes "Three major adaptations, or 'novel cardiac components', that were not present in the ancestor chordate heart tube can be distinguished in the lower vertebrate heart: the atrium, ventricle, and possibly the muscular sinus venosus. Furthermore, within the ventricular component a compact outer myocardial component and an interiorly localized extensive trabecular component can be distinguished. The specific activation of the ventricle adds to its complexity as follows. The depolarizing impulse travels rapidly from the atrioventricular node toward the apex and then toward the conal region, achieving activation from apex to base.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001474", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM\, Christoffels VM\, Cardiac Chamber Formation: Development\, Genes\, and Evolution. Physiological Reviews (2003)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0004247 [Term] id: UBERON:0002353 name: atrioventricular bundle def: "A part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers[GO]" [Wikipedia:Bundle_of_His, GOC:mtg_heart, GO:0003166] subset: uberon_slim synonym: "atrioventricular bundle muscle tissue" EXACT [FMA:9484] synonym: "atrioventricular fasciculus" EXACT [FMA:9484] synonym: "bundle of His" EXACT [FMA:9484, GO:0003166] synonym: "His bundle" EXACT [] synonym: "fasciculus atrioventricularis" EXACT LATIN [Wikipedia:Bundle_of_His] xref: FMA:9484 ! Atrioventricular bundle xref: GAID:559 ! bundle of his xref: galen:BundleOfHis xref: MA:0002576 ! atrioventricular bundle xref: OpenCyc:Mx4rUv1WcGPJEd2AAABQjYGu0g xref: ncithesaurus:Atrioventricular_Bundle ! Atrioventricular Bundle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b6/ECG_Principle_fast.gif/200px-ECG_Principle_fast.gif xref: MESH:A07.541.409.273 ! bundle of his is_a: UBERON:0001133 ! cardiac muscle tissue relationship: part_of UBERON:0002350 ! conducting system of heart relationship: part_of UBERON:0004146 {source="GO"} ! His-Purkinje system relationship: has_part CL:1000410 {source="FMA"} ! myocyte of atrioventricular node xref: SCTID:362022007 ! Entire atrioventricular bundle xref: http://upload.wikimedia.org/wikipedia/commons/5/50/ConductionsystemoftheheartwithouttheHeart.png xref: UMLS:C0006382 [Term] id: UBERON:0002354 name: purkinje fiber def: "Conducting tissue of heart which consists of Purkinje myocytes.[FMA]" [Wikipedia:Purkinje_fiber, FMA:FMA] subset: uberon_slim synonym: "myofibra conducens cardiacus" EXACT [] xref: FMA:9492 ! Purkinje fiber xref: GAID:560 ! purkinje fiber xref: MA:0000096 ! purkinje fiber xref: ncithesaurus:Purkinje_Fiber ! Purkinje Fiber xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/96/Gray498.png/200px-Gray498.png xref: MESH:A07.541.409.683 ! purkinje fiber (also: UBERON:0004147 'cardiac Purkinje fiber') is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart relationship: part_of UBERON:0002350 ! conducting system of heart relationship: has_part CL:0002068 {source="FMA"} ! Purkinje myocyte xref: UMLS:C0034144 [Term] id: UBERON:0002356 name: perineum def: "Subdivision of trunk proper, which is demarcated from the pelvis by the inferior surface of the pelvic diaphragm and from the lower limbs by the perineofemoral lines; together with the thorax, abdomen, and pelvis, it constitutes the trunk[FMA]." [Wikipedia:Perineum, FMA:9579] comment: AO Note: FMA has class anal part of perineum, which may be the same as what EHDAA2 calls perineum subset: uberon_slim synonym: "perineal region" EXACT [] xref: FMA:9579 ! Perineum xref: GAID:90 ! perineum xref: MA:0002466 ! perineum xref: OpenCyc:Mx4rvcHSh5wpEbGdrcN5Y29ycA xref: ncithesaurus:Perineum ! Perineum xref: galen:Perineum ! perineum xref: OpenCyc:Mx4rvcHSh5wpEbGdrcN5Y29ycA ! perineum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ef/Gray406.png/200px-Gray406.png xref: MESH:A01.719 ! perineum xref: EV:0100013 ! perineum is_a: UBERON:0009569 {source="FMA-modified"} ! subdivision of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0012469 {source="EHDAA2"} ! external anal region synonym: "regio perinealis" EXACT LATIN [FMA:TA, FMA:9579] xref: EHDAA2:0004015 ! perineum xref: SCTID:243990009 ! Entire perineum xref: http://upload.wikimedia.org/wikipedia/commons/e/ef/Gray406.png xref: EFO:0004141 ! perineum property_value: has_relational_adjective "perianal" xsd:string xref: UMLS:C0031066 [Term] id: UBERON:0012336 name: perianal skin synonym: "skin of perianal area" EXACT [] xref: FMA:29350 ! perianal skin xref: SCTID:181522009 ! Entire skin of perianal area intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002356 ! perineum [Term] id: UBERON:0002357 name: serous pericardium def: "Serous membrane which has as its parts the epicardium and parietal serous pericardium that surrounds pericardial cavity." [Wikipedia:Serous_pericardium] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "serous portion of pericardium" EXACT [] xref: FMA:9582 ! Serous pericardium xref: MA:0002739 ! serous pericardium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray968.png/200px-Gray968.png is_a: UBERON:0000042 ! serous membrane relationship: part_of UBERON:0002406 ! pericardial sac xref: SCTID:243954002 ! Entire serous pericardium synonym: "pericardium serosum" RELATED LATIN [Wikipedia:Serous_pericardium] xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray968.png [Term] id: UBERON:0003684 name: abdominal cavity def: "body cavity of the human body (and animal bodies) that holds the bulk of the viscera. It is located below (or inferior to) the thoracic cavity, and above the pelvic cavity. It is a part of the abdominopelvic cavity. Organs of the abdominal cavity include the stomach, liver, gallbladder, spleen, pancreas, small intestine, kidneys, and large intestine. The abdominal cavity is lined with a protective membrane termed the peritoneum. The kidneys are located in the abdominal cavity behind the peritoneum, in the retroperitoneum. The viscera are also covered, in the front, with a layer of peritoneum called the greater omentum (or omental apron)." [Wikipedia:Abdominal_cavity] synonym: "cavitas abdominis" RELATED [GAID:17] synonym: "cavity of abdominal compartment" EXACT [FMA:12266] synonym: "cavity of compartment of abdomen" EXACT [FMA:12266] synonym: "space of abdominal compartment" EXACT [FMA:12266] xref: FMA:12266 ! Abdominal cavity xref: GAID:17 ! abdominal cavity xref: ncithesaurus:Abdominal_Cavity ! Abdominal Cavity xref: EFO:0000213 ! abdominal cavity xref: galen:AbdominalCavity ! abdominal cavity xref: OpenCyc:Mx4rvZR1TJwpEbGdrcN5Y29ycA ! abdominal cavity xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Scheme_body_cavities-en.svg/200px-Scheme_body_cavities-en.svg.png xref: MESH:A01.047.025 ! abdominal cavity is_a: UBERON:0002323 ! coelemic cavity lumen relationship: part_of UBERON:0000916 ! abdomen xref: SCTID:361294009 ! Entire abdominal cavity synonym: "cavitas abdominis" RELATED LATIN [Wikipedia:Abdominal_cavity] xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg xref: UMLS:C0230168 [Term] id: UBERON:0003887 name: intraembryonic coelom def: "In the development of the human embryo the intraembryonic coelom (or somatic coelom) is a portion of the conceptus forming in the mesoderm. During the second week of development, the lateral mesoderm splits into a dorsal somatic mesoderm (somatopleure) and a ventral splanchnic mesoderm (splanchnopleure). The resulting cavity between the somatopleure and splanchnopleure is called the intraembryonic coelom. This space will give rise to the thoracic and abdominal cavities. It briefly has a connection with the extraembryonic coelom[WP]." [Wikipedia:Intraembryonic_coelom] comment: Editor notes: consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. Todo: check ZFA, which appears to be a structure present in adults synonym: "somatic coelom" EXACT [Wikipedia:Intraembryonic_coelom] xref: VHOG:0000316 ! intraembryonic coelom xref: EHDAA:251 ! intraembryonic coelom xref: ncithesaurus:Intraembryonic_Coelom ! Intraembryonic Coelom xref: EMAPA:16088 ! intraembryonic coelom is_a: UBERON:0003886 ! body cavity precursor relationship: develops_from UBERON:0003081 {source="Wikipedia"} ! lateral plate mesoderm property_value: homology_notes " (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG]" xsd:string {external_class="VHOG:0000316", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.166", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1512940 [Term] id: UBERON:0003888 name: extraembryonic coelom def: "cavity between Heuser's membrane and the Trophoblast[WP]." [Wikipedia:Extraembryonic_coelom] synonym: "chorionic cavity" EXACT [EHDAA2:0000246] synonym: "chorion cavity" EXACT [EHDAA2:0000246] synonym: "extraembryonic celom" EXACT [FMA:63943] synonym: "extraembryonic coelomic cavity" RELATED [VHOG:0001671] synonym: "exocoelomic cavity " RELATED [VHOG:0001671] xref: FMA:63943 ! Extraembryonic celom xref: EHDAA:146 ! chorionic cavity xref: ncithesaurus:Extraembryonic_Coelom ! Extraembryonic Coelom xref: EHDAA2:0000246 ! chorionic cavity xref: VHOG:0001671 ! exocoelomic cavity xref: EMAPA:16081 ! exocoelomic cavity is_a: UBERON:0003886 ! body cavity precursor relationship: located_in UBERON:0012466 {source="EHDAA2"} ! extraembryonic cavities xref: SCTID:362843009 ! Entire chorionic cavity synonym: "exocoelomic cavity" EXACT [VHOG:0001671] xref: UMLS:C1517055 [Term] id: UBERON:0004364 ! ectoplacental cone name: ectoplacental cone def: "thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta" [MP:0001717, PMID:19829370] comment: Development notes: derivative of the early postimplantation trophoblast, which probably gives rise to the spongiotrophoblast.[PMID:19829370] synonym: "epamniotic cone" EXACT [] synonym: "placenta - ectoplacental cone" EXACT [] xref: EMAPA:16059 ! ectoplacental cone xref: BTO:0001715 ! ectoplacental cone is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000088 ! trophoblast [Term] id: UBERON:0008851 ! ectoplacental cavity name: ectoplacental cavity def: "closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals" [http://www.medilexicon.com/medicaldictionary.php?s=epamniotic+cavity, MP:0011207] synonym: "epamniotic cavity" EXACT [http://www.medilexicon.com/medicaldictionary.php?s=epamniotic+cavity] synonym: "chorionic cavity" RELATED [MP:0011207] synonym: "epamniotic cavity" RELATED [MP:0011207] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0004364 ! ectoplacental cone relationship: part_of UBERON:0004364 ! ectoplacental cone xref: EMAPA:16080 ! ectoplacental cavity [Term] id: UBERON:0003886 name: body cavity precursor subset: grouping_class subset: non_informative intersection_of: UBERON:0000464 ! anatomical space intersection_of: develops_into UBERON:0002323 ! coelemic cavity lumen relationship: located_in UBERON:0000926 ! mesoderm def: "An anatomical cavity that develops_into a coelemic cavity lumen." [OBOL:automatic] [Term] id: UBERON:0011997 name: coelom def: "The structure that contains the coelemic cavity." [Wikipedia:Body_cavity, Wikipedia:Coelom] synonym: "coelomic cavity" RELATED [EHDAA2:0004731] synonym: "coelem" RELATED [] comment: Editor notes: EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining. is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0000922 {source="EHDAA2"} ! embryo relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} ! Acoelomorpha xref: EHDAA2:0004731 ! coelomic cavity property_value: has_relational_adjective "coelomic" xsd:string [Term] id: UBERON:0002323 name: coelemic cavity lumen def: "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities." [BTO:0001707] alt_id: UBERON:0000169 comment: Taxon notes: In mammals it forms the peritoneal, pleural, and pericardial cavities. editor note: check the FMA placement here; ncit placement of body cavity here probably not correct subset: uberon_slim subset: vertebrate_core synonym: "ventral body cavity" NARROW [] synonym: "coelom" RELATED [] synonym: "coelomic cavity" EXACT [] synonym: "space of body compartment" EXACT [FMA:85006] synonym: "celom" RELATED [BTO:0001707] synonym: "coelome" RELATED [BTO:0001707] synonym: "hemocoel" RELATED [FBbt:00005060] synonym: "coelomic cavity" EXACT [EHDAA2:0000267] synonym: "coelomic cavity lumen" EXACT [EHDAA2:0000267] xref: FBbt:00005060 ! hemocoel xref: TAO:0001438 ! coelom xref: ZFA:0001438 ! coelom xref: FMA:85006 ! Body cavity xref: galen:BodyCavity xref: MA:0002447 ! body cavity xref: ncithesaurus:Cavity ! Body Cavity xref: BTO:0001707 ! coelom xref: EHDAA2:0000267 ! coelomic cavity lumen xref: RETIRED_EHDAA2:0003186 ! body cavity xref: AEO:0000186 ! body cavity is_a: UBERON:0002553 ! anatomical cavity is_a: UBERON:0004458 {notes="pre-inferred via union_of"} ! body cavity or lining xref: SCTID:361348008 ! Entire body cavity relationship: develops_from UBERON:0003886 {evidence="definitional"} ! body cavity precursor property_value: external_definition "Anatomical space, part of the trunk that contains the pericardial and pleuroperitoneal cavities[ZFA]." xsd:string {ontology="ZFA", external_class="ZFA:0001438", date_retrieved="2012-09-12", source="ZFIN:curator"} property_value: external_definition "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities[BTO]." xsd:string {ontology="BTO", external_class="BTO:0001707", date_retrieved="2012-09-12", source="BTO"} xref: UMLS:C0333343 [Term] id: UBERON:0012054 name: myocoele def: "The cavity within a myotome" [http://medical-dictionary.thefreedictionary.com/myocoele] is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0003082 {source="VHOG"} ! myotome xref: VHOG:0001283 ! myocoele xref: EMAPA:16415 ! myocoele xref: EMAPA:16418 ! myocoele xref: EMAPA:16421 ! myocoele xref: EMAPA:16424 ! myocoele xref: EMAPA:16427 ! myocoele xref: EMAPA:16430 ! myocoele xref: EMAPA:16433 ! myocoele xref: EMAPA:16436 ! myocoele xref: EMAPA:16439 ! myocoele xref: EMAPA:16443 ! myocoele xref: EMAPA:16447 ! myocoele xref: EMAPA:16451 ! myocoele xref: EMAPA:16455 ! myocoele xref: EMAPA:16459 ! myocoele xref: EMAPA:16463 ! myocoele xref: EMAPA:16467 ! myocoele xref: EMAPA:16602 ! myocoele xref: EMAPA:16606 ! myocoele xref: EMAPA:16610 ! myocoele xref: EMAPA:16614 ! myocoele xref: EMAPA:16618 ! myocoele xref: EMAPA:16622 ! myocoele xref: EMAPA:16626 ! myocoele xref: EMAPA:16630 ! myocoele xref: EMAPA:16634 ! myocoele xref: EMAPA:16638 ! myocoele xref: EMAPA:16863 ! myocoele xref: EMAPA:16867 ! myocoele xref: EMAPA:16871 ! myocoele xref: EMAPA:16875 ! myocoele xref: EMAPA:16879 ! myocoele xref: EMAPA:17051 ! myocoele xref: EMAPA:17055 ! myocoele xref: EMAPA:17059 ! myocoele xref: EMAPA:17063 ! myocoele xref: EMAPA:17219 ! myocoele xref: EMAPA:17223 ! myocoele xref: EMAPA:17227 ! myocoele xref: EMAPA:17231 ! myocoele xref: EMAPA:17235 ! myocoele xref: EMAPA:17239 ! myocoele xref: EMAPA:17401 ! myocoele xref: EMAPA:17405 ! myocoele xref: EMAPA:17409 ! myocoele xref: EMAPA:17686 ! myocoele xref: EMAPA:17690 ! myocoele xref: EMAPA:17694 ! myocoele xref: EMAPA:17698 ! myocoele xref: EMAPA:18032 ! myocoele xref: EMAPA:18036 ! myocoele xref: EMAPA:18040 ! myocoele xref: EMAPA:18352 ! myocoele xref: EMAPA:18356 ! myocoele xref: EMAPA:18360 ! myocoele xref: EMAPA:18364 ! myocoele xref: EMAPA:18368 ! myocoele property_value: homology_notes "The central cavity within the mesoderm is the paired primary or embryonic coelom. Parts of the embryonic coelom often become enclosed in the mesoderm, forming a myocoel within the epimere, a nephrocoel within the mesomere, and simple coelom (body cavity) within the lateral plate mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001283", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.166 and Figure 5.6", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001179 name: peritoneal cavity def: "Cavity of serous sac surrounded by the peritoneum.[FMA]" [Wikipedia:Peritoneal_cavity, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "cavitas peritonealis" RELATED [BTO:0001782] xref: FMA:14704 ! Peritoneal cavity xref: GAID:24 ! peritoneal cavity xref: VHOG:0000852 ! peritoneal cavity xref: MA:0000054 ! peritoneal cavity xref: ncithesaurus:Peritoneal_Cavity ! Peritoneal Cavity xref: BTO:0001782 ! peritoneal cavity xref: EHDAA2:0001446 ! peritoneal cavity xref: EMAPA:18452 ! peritoneal cavity xref: EMAPA:18454 ! cavity of greater sac of peritoneal cavity (also: UBERON:0005450 'greater sac cavity') xref: EMAPA:18461 ! cavity of omental bursa of peritoneal cavity (also: UBERON:0005252 'omental bursa cavity') xref: MESH:A01.047.025.600.678 ! peritoneal cavity intersection_of: UBERON:0002323 ! coelemic cavity lumen intersection_of: part_of UBERON:0005906 ! serous sac intersection_of: surrounded_by UBERON:0002358 ! peritoneum relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom xref: SCTID:181616008 ! Entire peritoneal cavity synonym: "cavitas peritonealis; saccus serosus peritonei" RELATED LATIN [Wikipedia:Peritoneal_cavity] property_value: external_definition "The potential space between the parietal and visceral layers of the peritoneum, which are normally in contact. The peritoneal cavity is divided into the greater and lesser sac. The greater sac is the peritoneal cavity, and the lesser sac is the omental bursa. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000852", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/peritoneal+cavity", source="http://bgee.unil.ch/"} property_value: homology_notes "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes) Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {external_class="VHOG:0000852", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1704247 [Term] id: UBERON:0002358 name: peritoneum def: "A serous membrane that forms the lining of the abdominal cavity or the coelom — it covers most of the intra-abdominal (or coelomic) organs — in higher vertebrates and some invertebrates (annelids, for instance). It is composed of a layer of mesothelium supported by a thin layer of connective tissue. The peritoneum both supports the abdominal organs and serves as a conduit for their blood and lymph vessels and nerves[WP]. The smooth transparent serous membrane that lines the cavity of the abdomen of a mammal and is folded inward over the abdominal and pelvic viscera[BTO]. The endothelial lining of the ABDOMINAL CAVITY. The parietal peritoneum covers the inside of the ABDOMINAL WALL and the visceral peritoneum covers the bowel, the MESENTERY, and certain of the organs. The portion that covers the bowel becomes the serosal layer of the bowel wall[GAID]." [Wikipedia:Peritoneum, ZFIN:curator] comment: TODO - in ZFA is_a epithelium subset: uberon_slim subset: vertebrate_core xref: FMA:9584 ! Peritoneum xref: GAID:18 ! peritoneum xref: VHOG:0001257 ! peritoneum xref: TAO:0005120 ! peritoneum xref: XAO:0000139 ! peritoneum xref: ZFA:0005120 ! peritoneum xref: ncithesaurus:Peritoneum ! Peritoneum xref: BTO:0001472 ! peritoneum xref: galen:Peritoneum ! peritoneum xref: OpenCyc:Mx4rvjJ72ZwpEbGdrcN5Y29ycA ! peritoneum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Gray1040.png/200px-Gray1040.png xref: MESH:A01.047.025.600 ! peritoneum xref: EV:0100087 ! peritoneum is_a: UBERON:0000042 ! serous membrane relationship: located_in UBERON:0003684 ! abdominal cavity relationship: part_of UBERON:0003697 {source="MP"} ! abdominal wall relationship: develops_from UBERON:0000926 ! mesoderm xref: AAO:0010814 ! peritoneum xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png property_value: external_definition "Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010814", date_retrieved="2012-06-20", source="AAO:JMG"} property_value: external_definition "An epithelium that lines the peritoneal cavity.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005120", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "peritonaeum" RELATED [VHOG:0001257] property_value: has_relational_adjective "peritoneal" xsd:string xref: UMLS:C0031153 [Term] id: UBERON:0001366 name: parietal peritoneum alt_id: UBERON:0004459 def: "The peritoneum that lines the walls of the peritoneal cavity." [Wikipedia:Parietal_peritoneum, ZFIN:curator] comment: fix coordinated with ZFA subset: uberon_slim subset: vertebrate_core synonym: "peritoneal cavity lining" EXACT [MA:0000449] xref: FMA:21451 ! Parietal peritoneum xref: VHOG:0001527 ! parietal peritoneum xref: TAO:0005131 ! parietal peritoneum xref: ZFA:0005131 ! parietal peritoneum xref: MA:0000449 ! peritoneal cavity lining xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Gray1040.png/200px-Gray1040.png is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002358 ! peritoneum relationship: surrounds UBERON:0001179 ! peritoneal cavity xref: AAO:0010816 ! parietal peritoneum xref: SCTID:362700006 ! Entire parietal peritoneum property_value: external_definition "Peritoneum attached to the abdominal wall.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010816", date_retrieved="2012-06-20", source="AAO:JMG"} [Term] id: UBERON:0001178 name: visceral peritoneum def: "The peritoneum that covers the external surfaces of most abdominal organs." [Wikipedia:Visceral_peritoneum, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core xref: FMA:14703 ! Visceral peritoneum xref: VHOG:0001528 ! visceral peritoneum xref: TAO:0005132 ! visceral peritoneum xref: ZFA:0005132 ! visceral peritoneum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Gray1040.png/200px-Gray1040.png is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002358 ! peritoneum xref: SCTID:362702003 ! Entire visceral peritoneum [Term] id: UBERON:0007111 name: Douglas' pouch def: "The rectouterine pouch (or rectouterine excavation, rectovaginal, Ehrhardt-Cole Recess or Pouch of Douglas) is the extension of the peritoneal cavity between the rectum and back wall of the uterus in the female human body. The rectouterine pouch is used in the treatment of end-stage renal failure in patients who are treated by peritoneal dialysis. The tip of the dialysis catheter is placed into the deepest point of the pouch. In women it is the deepest point of the peritoneal cavity, posterior to (behind) the uterus and anterior to (in front of) rectum. (The pouch on the other side of the uterus is the vesicouterine excavation. ) It is near the posterior fornix of the vagina. In men, the region corresponding to the rectouterine pouch is the rectovesical excavation, which lies between the urinary bladder and rectum. (There is no equivalent to the vesicouterine excavation.)" [Wikipedia:Recto-uterine_pouch] synonym: "cul de sac of douglas" RELATED [MESH:A01.047.025.600.225] synonym: "cul-de-sac of douglsa" RELATED [MESH:A01.047.025.600.225] synonym: "douglas cul-de-sac" RELATED [MESH:A01.047.025.600.225] synonym: "douglas pouch" RELATED [MESH:A01.047.025.600.225] synonym: "douglas' cul de sac" RELATED [MESH:A01.047.025.600.225] synonym: "douglas' cul-de-sac" RELATED [MESH:A01.047.025.600.225] synonym: "douglas' pouch" RELATED [MESH:A01.047.025.600.225] synonym: "rectouterine pouch" EXACT [FMA:14728, MESH:A01.047.025.600.225] synonym: "recto-uterine pouch" EXACT [FMA:14728] synonym: "excavatio recto-uterina" EXACT [FMA:14728] synonym: "rectouterine excavation" RELATED [Wikipedia:Recto-uterine_pouch] synonym: "recto-uterine pouch" RELATED [Wikipedia:Recto-uterine_pouch] xref: MESH:A01.047.025.600.225 ! douglas' pouch xref: GAID:20 ! douglas' pouch xref: FMA:14728 ! Rectouterine pouch xref: ncithesaurus:Recto-Vaginal_Pouch ! recto-vaginal pouch is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002358 ! peritoneum synonym: "excavatio rectouterina" EXACT LATIN [FMA:TA, FMA:14728] xref: SCTID:181447009 ! Entire rectouterine pouch synonym: "excavatio rectouterina" RELATED LATIN [Wikipedia:Recto-uterine_pouch] synonym: "cavum Douglassi" RELATED LATIN [Wikipedia:Recto-uterine_pouch] synonym: "fossa Douglasi" RELATED LATIN [Wikipedia:Recto-uterine_pouch] xref: http://upload.wikimedia.org/wikipedia/commons/5/51/WeiblichesBeckenMedian.gif synonym: "pouch of douglas" EXACT [FMA:14728] synonym: "rectouterine space" RELATED [FMA:14728] xref: UMLS:C1514801 [Term] id: UBERON:0011204 name: rectovesical pouch def: "Between the rectum and the bladder the peritoneal cavity forms, in the male, a pouch, the rectovesical excavation (or rectovesical pouch), the bottom of which is slightly below the level of the upper ends of the vesiculae seminalesbi. e. , about 7.5 cm. from the orifice of the anus. its lowest part membranous partition called Rectoprostatic fascia. The corresponding structure in women is the rectouterine pouch." [Wikipedia:Recto-vesical_pouch] synonym: "excavatio rectovesicalis" RELATED [Wikipedia:Recto-vesical_pouch] synonym: "rectovesical" RELATED [Wikipedia:Recto-vesical_pouch] synonym: "rectovesical excavation" RELATED [Wikipedia:Recto-vesical_pouch] synonym: "rectovesical pouch" RELATED [Wikipedia:Recto-vesical_pouch] synonym: "retrovesical excavation" RELATED [Wikipedia:Recto-vesical_pouch] synonym: "excavatio rectovesicalis" EXACT LATIN [FMA:TA] synonym: "recto-vesical pouch" EXACT [FMA:14727] synonym: "rectovesical space" EXACT [FMA:14727] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002358 ! peritoneum xref: FMA:14727 ! rectovesical pouch xref: ncithesaurus:Recto-Vesical_Pouch ! recto-vesical pouch xref: SCTID:261416006 ! Entire rectovesical pouch xref: http://upload.wikimedia.org/wikipedia/commons/4/45/Gray1228.png xref: UMLS:C0230301 [Term] id: UBERON:0007136 name: rectouterine fold def: "These folds of the rectouterine excavation are named the sacrogenital or rectouterine folds. They contain a considerable amount of fibrous tissue and non-striped muscular fibers which are attached to the front of the sacrum and constitute the uterosacral ligaments." [Wikipedia:Recto-uterine_fold] synonym: "fold of Douglas" EXACT [FMA:16533] synonym: "posterior ligament of uterus" EXACT [FMA:16533] synonym: "recto-uterine fold" EXACT [FMA:16533] synonym: "rectovaginal fold" EXACT [FMA:16533] xref: FMA:16533 ! rectouterine fold is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002358 ! peritoneum synonym: "plica rectouterina" EXACT LATIN [FMA:TA, FMA:16533] xref: SCTID:361301006 ! Entire posterior ligament of uterus synonym: "plica rectouterina" RELATED LATIN [Wikipedia:Recto-uterine_fold] xref: http://upload.wikimedia.org/wikipedia/commons/b/b5/Gray1165.png [Term] id: UBERON:0001297 name: serosa of uterus def: "Outer serosa layer of the uterus." [Wikipedia:Perimetrium] comment: TODO - check for parallel structure with peritoneum synonym: "perimetrium" EXACT [http://en.wikipedia.org/wiki/Perimetrium] synonym: "serous coat of uterus" EXACT [] synonym: "tunica serosa (perimetrium)" EXACT [] synonym: "uterine serosa" EXACT [] synonym: "uterus serosa" EXACT [] synonym: "visceral peritoneum of uterus" EXACT [] synonym: "serous membrane of uterus" EXACT [OBOL:automatic] synonym: "uterus serous membrane" EXACT [OBOL:automatic] synonym: "tunica serosa uteri" EXACT LATIN [FMA:TA, FMA:17744] xref: FMA:17744 ! Serosa of uterus xref: MA:0001729 ! uterus serosa xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Illu_cervix.jpg/200px-Illu_cervix.jpg is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus xref: ncithesaurus:Perimetrium ! Perimetrium xref: SCTID:253705006 ! Entire uterine serosa xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg relationship: part_of UBERON:0000459 {source="reference_0000032"} ! uterine wall xref: UMLS:C0227824 [Term] id: UBERON:0005741 name: adventitia of uterus xref: EMAPA:29925 ! adventitia xref: EMAPA:29933 ! adventitia of cervix uteri is_obsolete: true consider: UBERON:0001297 ! serosa of uterus [Term] id: UBERON:0002359 name: fibrous pericardium def: "Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]" [Wikipedia:Fibrous_pericardium, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "fibrous portion of pericardium" EXACT [] xref: FMA:9586 ! Fibrous pericardium xref: MA:0002738 ! fibrous pericardium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray968.png/200px-Gray968.png xref: EMAPA:19029 ! fibrous pericardium is_a: UBERON:0000094 ! membrane organ relationship: part_of UBERON:0002407 ! pericardium xref: SCTID:243953008 ! Entire fibrous portion of pericardium subset: organ_slim synonym: "pericardium fibrosum" RELATED LATIN [Wikipedia:Fibrous_pericardium] xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray968.png [Term] id: UBERON:0007646 ! endomeninx name: endomeninx def: "the layer of embryonic mesoderm from which the arachnoid coat and pia mater of the brain develop." [http://www.merriam-webster.com/medical/endomeninx] is_a: UBERON:0007645 ! future meninx [Term] id: UBERON:0007647 ! ectomeninx name: ectomeninx def: "the layer of mesoderm from which the dura mater and much of the membrane bone of the skull develop in the higher vertebrate embryo." [http://www.merriam-webster.com/medical/ectomeninx] is_a: UBERON:0007645 ! future meninx relationship: develops_from UBERON:0000926 ! mesoderm [Term] id: UBERON:0007645 ! future meninx name: future meninx comment: The zebrafish primitive meninx develops from neural crest[UBERONREF:0000002]. In EHDAA2 the meninges are divided by layer and location, each has differing developmental origins - mesenchyme from mesoderm/endoderm, mesenchyme from NC synonym: "primitive meninx" RELATED [] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_into UBERON:0002360 ! meninx relationship: has_developmental_contribution_from UBERON:0002342 {source="ISBN10:0073040584"} ! neural crest relationship: has_developmental_contribution_from UBERON:0000926 ! mesoderm [Term] id: UBERON:0010743 ! meningeal cluster name: meningeal cluster def: "The collection of all meningeal layers that line a central nervous system." [UBERON:cjm] comment: In some primitive organisms, the meningeal cluster includes only the primitive meninx synonym: "cluster of meninges" EXACT [FMA:231572] synonym: "meninges" EXACT [FMA:231572] xref: FMA:231572 ! Meningeal cluster xref: EHDAA2:0004661 ! meninges xref: SCTID:362879001 ! Entire meninges is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001017 ! central nervous system property_value: has_relational_adjective "meningeal" xsd:string [Term] id: UBERON:0002360 name: meninx def: "Membrane organ that surrounds the brain and the spinal cord." [http://www.shsu.edu/~bio_mlt/Chap15.html, Wikipedia:Meninx, FMA:9589] comment: Editor note: consider separate term for meninges aka collection of meninges. Note in EHDAA2 pia mater etc are part of the meninges. Also consider a new class for primary/primitive meninx. AO notes: Not consider part of the CNS/neuraxis in FMA. Taxon notes: Whereas cyclostomes and fishes only have a single envelope called the primitive meninx, amphibians have two layers, consisting of an outer dura mater which is extremely dense and protective, and a pia-arachnoid or secondary meninx which is more delicate and vascular. Mammals have three meninges: pia mater (which follows all the convolutions of the brain and is the most interior), the arachnoid layer (which is delicate and sends strands to the pia mater), and the dura mater (the outer, more protective meninx). subset: uberon_slim subset: vertebrate_core synonym: "layer of meninges" EXACT [] synonym: "meningeal layer" EXACT [] xref: BTO:0000144 xref: EFO:0000584 xref: EFO:0000867 ! meninges xref: FMA:9589 ! Meninx xref: GAID:687 ! meninge xref: VHOG:0001295 ! meninges xref: MA:0001113 ! meninges xref: MAT:0000113 ! meninges xref: ncithesaurus:Meninges xref: ZFA:0001355 ! primitive meninx xref: OpenCyc:Mx4rwDOl8JwpEbGdrcN5Y29ycA ! meninx xref: NIF_GrossAnatomy:nlx_anat_090204 ! Meninx xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/48/Illu_meninges.jpg/200px-Illu_meninges.jpg xref: MESH:A08.186.566 ! meninge xref: EV:0100312 ! meninges (also: UBERON:0003547 'brain meninx') is_a: UBERON:0000094 {source="FMA"} ! membrane organ relationship: part_of UBERON:0010743 ! meningeal cluster relationship: develops_from UBERON:0002342 {gci_relation="part_of", gci_filler="NCBITaxon:7955", notes="primitive", source="UBERONREF:0000002"} ! neural crest subset: organ_slim xref: TAO:0001355 ! primitive meninx synonym: "meninx primitiva" NARROW [VHOG:0001295] property_value: external_definition "Membrane covering the brain and spinal cord. It is represented by a single layer in fishes, two in amphibians, reptiles and birds and three in mammals (named dura mater, arachnoid and pia mater). [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001295", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/meninges", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001295", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "meningeal" xsd:string xref: UMLS:C0025285 [Term] id: UBERON:0000391 ! leptomeninx name: leptomeninx def: "pia mater or arachnoid mater." [Wikipedia:Leptomeninges] comment: AO notes: in FMA/NIF this is a superclass of PM/AM - in BTO it is the mereological sum. We go with superclass here, as we are naming the class in the singular. Editor notes: check relationship to secondary meninx synonym: "leptomeninges" EXACT PLURAL [NIF_GrossAnatomy:nlx_anat_090207] synonym: "arachnoidea mater et pia mater" RELATED [BTO:0001634] synonym: "pia-arachnoid" RELATED [BTO:0001634] xref: BTO:0001634 xref: FMA:231515 ! Leptomeninx xref: NIF_GrossAnatomy:nlx_anat_090207 ! Leptomeninx is_a: UBERON:0002360 ! meninx relationship: develops_from UBERON:0007646 ! endomeninx xref: ncithesaurus:Leptomeninges ! Leptomeninges xref: SCTID:362303006 ! Entire leptomeninges subset: organ_slim xref: UMLS:C0228126 [Term] id: UBERON:0002361 name: pia mater def: "delicate innermost layer of the meninges—the membranes surrounding the brain and spinal cord. The thin, mesh-like pia mater closely envelops the entire surface of the brain, running down into the fissures of the cortex. It joins with the ependyma which lines the ventricles to form choroid plexuses that produce cerebrospinal fluid. In the spinal cord, the pia mater attaches to the dura mater by the denticular ligaments through the arachnoid membrane. The pia mater is a neural crest derivative." [Wikipedia:Pia_mater] comment: Editor note: consider adding adjacency relationship to neuraxis (brain+spinal cord); however note that at this time the meninges may be considered part of the nervous system subset: uberon_slim synonym: "pia mater of neuraxis" EXACT [] synonym: "pial membrane" EXACT [NIF_GrossAnatomy:nlx_anat_090209] xref: EHDAA:1367 ! pia mater xref: EHDAA:1961 ! pia mater xref: EHDAA:2001 ! pia mater xref: EHDAA:2099 ! pia mater xref: EHDAA:2685 ! pia mater xref: EHDAA:2833 ! pia mater xref: EHDAA:2867 ! pia mater xref: EHDAA:3692 ! pia mater xref: EHDAA:3710 ! pia mater xref: EHDAA:6566 ! pia mater xref: EHDAA:6583 ! pia mater xref: FMA:9590 ! Pia mater xref: GAID:693 ! pia mater xref: MA:0001116 ! pia mater xref: ncithesaurus:Pia_Mater ! Pia Mater xref: BTO:0001635 ! pia mater xref: OpenCyc:Mx4rvtesBZwpEbGdrcN5Y29ycA ! pia mater xref: NIF_GrossAnatomy:nlx_anat_090209 ! Pial membrane xref: RETIRED_EHDAA2:0001464 ! pia mater xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/65/Gray770.png/200px-Gray770.png xref: MESH:A08.186.566.731 ! pia mater xref: EV:0100315 ! pia mater (also: UBERON:0003549 'brain pia mater') is_a: UBERON:0000391 ! leptomeninx relationship: only_in_taxon NCBITaxon:40674 {source="ISBN10:0073040584", notes="check-aves"} ! Mammalia xref: SCTID:362305004 ! Entire pia mater xref: EHDAA2:0004318 ! pia mater xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Gray770-en.svg xref: UMLS:C0031869 [Term] id: UBERON:0002362 name: arachnoid mater def: "A think avascular meningeal layer, between the pia mater and the dural mater. It is separated from the pia mater by the subarachnoid space." [Wikipedia:Arachnoid_mater, ISBN10:0471888893] subset: uberon_slim synonym: "arachnoid" EXACT [] synonym: "arachnoid mater of neuraxis" EXACT [] synonym: "arachnoid membrane" EXACT [NIF_GrossAnatomy:nlx_anat_090208] synonym: "arachnoidea mater" RELATED [BTO:0001636] xref: ncithesaurus:Arachnoid_Membrane ! Arachnoid Membrane xref: FMA:9591 ! Arachnoid mater xref: GAID:688 ! arachnoid xref: MA:0001114 ! arachnoid mater xref: OpenCyc:Mx4rve5HlJwpEbGdrcN5Y29ycA xref: NIF_GrossAnatomy:nlx_anat_090208 ! Arachnoid membrane xref: BTO:0001636 ! arachnoid mater xref: OpenCyc:Mx4rve5HlJwpEbGdrcN5Y29ycA ! arachnoid mater xref: NIF_GrossAnatomy:nlx_anat_090208 ! Arachnoid membrane xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Gray767.png/200px-Gray767.png xref: MESH:A08.186.566.166 ! arachnoid xref: EV:0100314 ! arachnoid is_a: UBERON:0000391 ! leptomeninx relationship: only_in_taxon NCBITaxon:40674 {source="ISBN10:0073040584"} ! Mammalia relationship: spatially_disjoint_from UBERON:0002049 {source="ISBN10:0471888893"} ! vasculature xref: SCTID:362304000 ! Entire arachnoid xref: http://upload.wikimedia.org/wikipedia/commons/a/a0/Gray767.png xref: UMLS:C1510935 [Term] id: UBERON:0000437 name: arachnoid barrier layer def: "The arachnoid barrier layer is a part of the arachnoid meningeal layer. It is formed by tight junctions between the endothelial cells of cerebral capillaries in the arachnoid mater." [BTO:0002498] xref: BTO:0002498 xref: FMA:231559 ! Arachnoid barrier layer is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0002362 {source="FMA"} ! arachnoid mater [Term] id: UBERON:0000416 name: subdural space def: "A narrow fluid-containing space, often only a potential space, between the dura mater and the arachnoid." [BTO:0002082, Wikipedia:Subdural_space, PMID:8421539] comment: Consider obsoleting - see PMID:8421539 synonym: "cavum subdurale" RELATED [BTO:0002082] synonym: "spatium subdurale" RELATED [BTO:0002082] synonym: "subdural cavity" RELATED [BTO:0002082] synonym: "subdural cleavage" RELATED [BTO:0002082] synonym: "subdural cleft" RELATED [BTO:0002082] xref: BTO:0002082 xref: FMA:83803 ! Subdural space xref: GAID:692 ! subdural space xref: MESH:A08.186.566.395.687 ! subdural space is_a: UBERON:0000464 ! anatomical space relationship: adjacent_to UBERON:0002363 ! dura mater relationship: adjacent_to UBERON:0002362 ! arachnoid mater xref: SCTID:362308002 ! Entire subdural space synonym: "spatium subdurale, cavum subdurale" RELATED LATIN [Wikipedia:Subdural_space] xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray769-en.svg [Term] id: UBERON:0005397 name: brain arachnoid mater synonym: "cranial arachnoid mater" EXACT [FMA:83981] synonym: "brain arachnoid matter" EXACT [MA:0000814] xref: MA:0000814 ! brain arachnoid matter xref: VHOG:0000230 ! brain arachnoid mater xref: FMA:83981 ! cranial arachnoid mater intersection_of: UBERON:0002362 ! arachnoid mater intersection_of: surrounds UBERON:0000955 ! brain relationship: part_of UBERON:0003547 ! brain meninx property_value: external_definition "The middle membrane of the three mammalian meninges covering the brain and spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000230", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/arachnoid+mater", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000230", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An arachnoid mater that surrounds a brain." [OBOL:automatic] [Term] id: UBERON:0010115 name: future dura mater is_a: UBERON:0002360 ! meninx intersection_of: UBERON:0002360 ! meninx intersection_of: develops_into UBERON:0002363 ! dura mater xref: EHDAA2:0004317 ! future dura mater def: "A meninx that develops_into a dura mater." [OBOL:automatic] [Term] id: UBERON:0002363 name: dura mater def: "the outermost of the three layers of the meninges surrounding the brain and spinal cord. The other two meningeal layers are the pia mater and the arachnoid mater. The dura surrounds the brain and the spinal cord and is responsible for keeping in the cerebrospinal fluid." [Wikipedia:Dura_mater] comment: Function notes: capable of inducing chondrogenesis - requires contact with an epithelium - PMID:16496288. AO notes: in ncit this is divided into periosteal layer and meningeal layer subset: uberon_slim synonym: "dura mater of neuraxis" EXACT [] synonym: "pachymeninges" EXACT [NIF_GrossAnatomy:nlx_anat_090206] synonym: "dura" RELATED [BTO:0001637] xref: FMA:9592 ! Dura mater xref: GAID:691 ! dura mater xref: MA:0001115 ! dura mater xref: EMAPA:17776 ! dura mater of meninges of telencephalon of forebrain xref: ncithesaurus:Dura_Mater ! Dura Mater xref: BTO:0001637 ! dura mater xref: OpenCyc:Mx4rvvmzqZwpEbGdrcN5Y29ycA ! dura mater xref: NIF_GrossAnatomy:nlx_anat_090206 ! Dura mater xref: MESH:A08.186.566.395 ! dura mater xref: EV:0100313 ! dura mater (also: UBERON:0002092 'brain dura mater') is_a: UBERON:0002360 ! meninx relationship: develops_from UBERON:0007647 ! ectomeninx relationship: immediate_transformation_of UBERON:0010115 {evidence="definitional"} ! future dura mater relationship: never_in_taxon NCBITaxon:32443 {source="ISBN10:0073040584"} ! Teleostei relationship: continuous_with UBERON:0001773 {source="PMID:16496288"} ! sclera xref: SCTID:362301008 ! Entire dura mater subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/8/8e/Meninges-en.svg xref: UMLS:C0013313 [Term] id: UBERON:0010507 name: layer of dura mater def: "The intracranial dura mater, consisting of two layers: the outer periosteal layer which normally always adheres to the periosteum of the bones of the cranial vault; and the inner meningeal layer which in most places is fused with the outer. The two layers separate to accommodate meningeal vessels and large venous (dural) sinuses. The meningeal layer is also involved in the formation of the various dural folds, such as the falx cerebri and tentorium cerebelli and is comparable to and continuous with the dural mater of the spinal cord. The cranial epidural space is then a potential space between the bone and the combined periosteum/periosteal layer of the dura mater realised only pathologically and is neither continuous with or comparable to the vertebral epidural space" [http://www.mondofacto.com/facts/dictionary?periosteal+layer+of+dura+mater] comment: Editors note: not clear whether this should be classified as part of cranial dura mater, as the division only makes sense in this area is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0002363 {source="FMA"} ! dura mater xref: FMA:231545 ! layer of dura mater [Term] id: UBERON:0010505 ! periosteal dura mater name: periosteal dura mater def: "The outermost of the two layers of the cranial dura mater which normally always adheres to the periosteum of the bones of the cranial vault" [UBERON:cjm] synonym: "periosteal layer of dura mater" EXACT [FMA:231547] synonym: "outer periosteal layer of dura mater" EXACT [] synonym: "periosteal dura" EXACT [FMA:231547] synonym: "outer layer of dura mater" EXACT [FMA:231547] is_a: UBERON:0010507 {source="FMA"} ! layer of dura mater relationship: part_of UBERON:0002092 ! cranial dura mater relationship: adjacent_to UBERON:0003129 ! skull relationship: adjacent_to UBERON:0002515 ! periosteum relationship: spatially_disjoint_from UBERON:0010506 ! meningeal dura mater xref: FMA:231547 ! outer layer of dura mater xref: ncithesaurus:Periosteal_Layer_of_the_Dura_Mater ! periosteal layer of the dura mater xref: UMLS:C1518991 [Term] id: UBERON:0010506 ! meningeal dura mater name: meningeal dura mater comment: Editors note: not clear whether this should be classified as part of cranial dura mater, as the division only makes sense in this area synonym: "meningeal layer of dura mater" EXACT [FMA:231549] synonym: "meningeal dura" EXACT [FMA:231549] synonym: "inner layer of dura mater" EXACT [FMA:231549] is_a: UBERON:0010507 {source="FMA"} ! layer of dura mater xref: FMA:231549 ! inner layer of dura mater xref: ncithesaurus:Meningeal_Layer_of_the_Dura_Mater ! meningeal layer of the dura mater xref: UMLS:C1513121 [Term] id: UBERON:0010090 name: future falx cerebri is_a: UBERON:0007524 ! dense mesenchyme tissue intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: develops_into UBERON:0006059 ! falx cerebri xref: EHDAA2:0000608 ! future falx cerebri def: "A developing anatomical structure that develops_into a falx cerebri." [OBOL:automatic] [Term] id: UBERON:0006059 name: falx cerebri def: "The falx cerebri, also known as the cerebral falx, so named from its sickle-like form, is a strong, arched fold of dura mater which descends vertically in the longitudinal fissure between the cerebral hemispheres. It is narrow in front, where it is attached to the crista galli of the ethmoid; and broad behind, where it is connected with the upper surface of the tentorium cerebelli. Its upper margin is convex, and attached to the inner surface of the skull in the middle line, as far back as the internal occipital protuberance; it contains the superior sagittal sinus. Its lower margin is free and concave, and contains the inferior sagittal sinus. The falx cerebri is known to calcify with age." [Wikipedia:Falx_cerebri] synonym: "cerebral falx" EXACT [FMA:83967] xref: EMAPA:18551 ! falx cerebri xref: FMA:83967 ! falx cerebri is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002363 ! dura mater xref: ncithesaurus:Falx_Cerebri ! Falx Cerebri xref: SCTID:279275004 ! Entire falx cerebri relationship: immediate_transformation_of UBERON:0010090 {evidence="definitional"} ! future falx cerebri xref: http://upload.wikimedia.org/wikipedia/commons/f/ff/Falxcerebri.jpg xref: UMLS:C0228120 [Term] id: UBERON:0002365 name: exocrine gland def: "A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas" [Wikipedia:Exocrine_gland] comment: Editor's note: Currently this is logically defined by the system it belongs to, but a better system may be base this on presence/absence of ducts. However, the dual nature of the liver should be taken into consideration here. Consider adding subclasses subset: uberon_slim synonym: "ducted gland" EXACT [AEO:0000097] xref: BTO:0000765 xref: FMA:9596 ! Exocrine gland xref: GAID:34 ! exocrine gland xref: MA:0002564 ! exocrine gland xref: ncithesaurus:Exocrine_Gland ! Exocrine Gland xref: EHDAA2:0003097 ! ducted gland xref: AEO:0000097 ! ducted gland xref: MESH:A10.336 ! exocrine gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002330 ! exocrine system relationship: has_part UBERON:0000058 ! duct subset: organ_slim synonym: "glandula exocrina" EXACT LATIN [Wikipedia:Exocrine_gland] xref: UMLS:C0015282 [Term] id: UBERON:0002366 ! bulbo-urethral gland name: bulbo-urethral gland def: "Any of the small paired racemose glands below the apex of the prostate in males, located posterolateral to the membranous portion of the urethra at the base of the penis, between the two layers of the fascia of the urogenital diaphragm, in the deep perineal pouch, and enclosed by transverse fibers of the sphincter urethrae membranaceae muscle; homologous to the greater vestibular (Bartholin's) glands in the female[MP]" [Wikipedia:Bulbourethral_gland, MP:anna] comment: Structure notes: The bulbourethral glands are compound tubulo-alveolar glands. AO notes: see comments for paraurethral gland - ncita placement may not be correct subset: uberon_slim synonym: "bulbourethral gland" EXACT [FMA:9599] synonym: "Cowper's gland" EXACT [FMA:9599] synonym: "Cowper's glands" EXACT PLURAL [FMA:9599] synonym: "Mery's gland" EXACT [] synonym: "Méry gland" EXACT [MP:anna] synonym: "glandula bulbourethralis" EXACT LATIN [MP:anna] xref: FMA:9599 ! Bulbo-urethral gland xref: GAID:387 ! bulbourethral gland xref: MA:0000401 ! bulbourethral gland xref: BTO:0001698 ! bulbourethral gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/35/Male_anatomy.png/200px-Male_anatomy.png xref: EMAPA:19286 ! bulbourethral gland xref: MESH:A05.360.444.123 ! bulbourethral gland is_a: UBERON:0010147 ! male accessory sex gland relationship: part_of UBERON:0001333 {source="MA", notes="check this"} ! male urethra relationship: part_of UBERON:0002330 ! exocrine system relationship: homologous_to UBERON:0000460 ! major vestibular gland relationship: secretes UBERON:0004691 ! bulbourethral gland secretion property_value: external_definition "Lobular organ the parenchyma of which consists of glandular acini which communicate the bulbar part of the urethra. Examples: There only two instances, right and left bulbo-urethral glands[FMA]" xsd:string {ontology="FMA", source="FMA:9599"} property_value: external_definition "Either of two small racemose glands that are located below the prostate and discharge a component of the seminal fluid into the urethra. They are homologous to the Bartholin's glands in the female[BTO]." xsd:string {ontology="BTO", source="BTO:0001698"} property_value: external_definition "any of the small paired racemose (compound tubulo-alveolar) glands below the apex of the prostate in males, located posterolateral to the membranous portion of the urethra at the base of the penis, between the two layers of the fascia of the urogenital diaphragm, in the deep perineal pouch, and enclosed by transverse fibers of the sphincter urethrae membranaceae muscle; they secrete a clear fluid known as pre-ejaculate (Cowper's fluid), and are homologous to the greater vestibular (Bartholin's) glands in the female[MP]." xsd:string {ontology="MP", source="MP:0001169"} xref: SCTID:278918009 ! Entire bulbourethral gland xref: ncithesaurus:Cowper_s_Gland ! cowper gland subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png xref: UMLS:C0006366 [Term] id: UBERON:0010151 ! duct of bulbourethral gland name: duct of bulbourethral gland synonym: "bulbourethral gland duct" EXACT [FMA:20091] synonym: "duct of bulbo-urethral gland" EXACT [FMA:20091] synonym: "ductus glandulae bulbourethralis" EXACT LATIN [FMA:TA] intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0002366 ! bulbo-urethral gland xref: FMA:20091 ! duct of bulbourethral gland xref: SCTID:279709005 ! Entire duct of bulbourethral gland def: "A duct that is part of a bulbo-urethral gland." [OBOL:automatic] [Term] id: UBERON:0009847 ! prostate field name: prostate field def: "a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop." [GOC:dph, PMID:18977204, GO:0060515] synonym: "prostate primordium" EXACT [] is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004902 {source="PMID:18977204"} ! urogenital sinus epithelium relationship: induced_by UBERON:0009845 {source="PMID:18977204"} ! urogenital sinus mesenchyme [Term] id: UBERON:0003820 ! prostate bud name: prostate bud def: "A region of the fetal urogenital sinus epithelium destined to become the prostate[GO]." [GO:0060513] comment: AR activation releases instructive signals from UGM that acts on UGS epithelium (UGE) to stimulate cell proliferation, form prostate ductal progenitors (prostatic buds), and regulate cell adhesion dynamics to permit prostatic bud outgrowth. There are three phases of prostatic budding: (1) the specification phase, when instructive developmental cues define where buds will form in the UGS, (2) the initiation phase, when prostatic buds begin to form, and (3) the elongation phase, when proliferation, cell adhesion, and cell migration coordinate outgrowth of prostatic buds into UGM. Timing of prostatic bud formation and the quantity and pattern of buds that are formed in the UGS are strictly regulated [3, 4]. The position of prostatic buds as they emerge from the UGS in utero determines the arrangement of prostate ducts in adulthood.[PMID:18977204] synonym: "prostatic bud" EXACT [] synonym: "prostate ductal progenitor" EXACT [PMID:18977204] is_a: UBERON:0005153 {source="GO:0060572"} ! epithelial bud relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0009847 {source="PMID:18977204"} ! prostate field [Term] id: UBERON:0004179 name: prostate glandular acinus def: "A saclike structure of the prostate gland, comprised of at least three cell layers: an innermost layer of secretory columnar luminal epithelium, a middle layer of squamous basal epithelium that also contains neuroendocrine cells, transit amplifying cells, and stem cells, and an outer layer of smooth muscle intermixed with other stromal cells" [GO:0060525, PMID:18977204] comment: Concurrent with branching morphogenesis, the solid cords of epithelium formed by budding arborize and differentiate postnatally into glandular acin. The basic prostate architecture is established by puberty and acquires secretory function thereafter[PMID:18977204] synonym: "prostatic follicle" EXACT [FMA:66808] synonym: "prostatic acinus" EXACT [FMA:66808] is_a: UBERON:0009842 {source="FMA"} ! acinus relationship: part_of UBERON:0002367 ! prostate relationship: part_of UBERON:0000428 {source="GO"} ! prostate epithelium relationship: develops_from UBERON:0009843 {source="PMID:18977204"} ! prostate epithelial cord xref: FMA:66808 ! prostatic acinus [Term] id: UBERON:0002367 name: prostate gland def: "The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid." [Wikipedia:Prostate, GO:0030850] comment: TODO - FMA treats the gland as part of the prostate - see also FMA:74119. subset: uberon_slim subset: major_organ synonym: "prostate" EXACT [] synonym: "male prostate" EXACT [PMID:10668204] xref: BTO:0001129 xref: EFO:0000858 ! prostate xref: FMA:9600 ! Prostate xref: GAID:392 ! prostate xref: VHOG:0001261 ! prostate xref: MA:0000404 ! prostate gland xref: MAT:0000078 ! prostate xref: MIAA:0000078 ! prostate xref: ncithesaurus:Prostate_Gland xref: OpenCyc:Mx4rv6trqZwpEbGdrcN5Y29ycA xref: galen:ProstateGland ! prostate gland xref: OpenCyc:Mx4rv6trqZwpEbGdrcN5Y29ycA ! prostate xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a1/Prostatelead.jpg/200px-Prostatelead.jpg xref: EMAPA:19287 ! prostate gland xref: MESH:A05.360.444.575 ! prostate xref: EV:0100104 ! prostate is_a: UBERON:0010147 ! male accessory sex gland relationship: develops_from UBERON:0003820 ! prostate bud relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia xref: SCTID:181422007 ! Entire prostate subset: organ_slim synonym: "prostata" RELATED LATIN [Wikipedia:Prostate] xref: http://upload.wikimedia.org/wikipedia/commons/a/a1/Prostatelead.jpg property_value: has_relational_adjective "prostatic" xsd:string xref: UMLS:C0033572 [Term] id: UBERON:0002485 name: prostate duct def: "the minute canals that pass the prostatic secretions to the urethra." [MP:0009734] synonym: "duct of prostate" EXACT [] synonym: "duct of prostate gland" EXACT [] synonym: "prostate gland duct" EXACT [] synonym: "prostate duct" EXACT [] synonym: "prostatic duct" EXACT [] xref: FMA:19580 ! Prostatic duct xref: MA:0002785 ! prostate duct xref: ncithesaurus:Prostatic_Duct ! Prostatic Duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0002367 ! prostate relationship: develops_from UBERON:0003820 {source="PMID:18977204"} ! prostate bud xref: SCTID:362276000 ! Entire prostatic duct xref: UMLS:C0227965 [Term] id: UBERON:0012247 name: cervical gland def: "mucus-secreting glands in the mucosa of the uterine cervix" [http://www.thefreedictionary.com/cervical+glands] is_a: UBERON:0000414 ! mucous gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: part_of UBERON:0000002 ! uterine cervix relationship: part_of UBERON:0012248 ! cervical mucosa synonym: "glandulae cervicales" EXACT [FMA:TA] xref: ncithesaurus:Cervical_Gland ! cervical gland xref: FMA:71646 ! set of cervical glands xref: SCTID:280836000 ! Entire endocervical gland xref: UMLS:C2724437 [Term] id: UBERON:0012248 ! cervical mucosa name: cervical mucosa def: "Lining of the head of the uterus (cervix); contains large branched glands; does not undergo sloughing." [BTO:0000411] intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000002 ! uterine cervix xref: BTO:0000411 ! cervical mucosa [Term] id: UBERON:0000316 name: cervical mucus def: "A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus." [BTO:0000242, Wikipedia:Cervix#Cervical_mucus, Wikipedia:Mucus#Reproductive_system] synonym: "cervix mucus" EXACT [OBOL:automatic] xref: BTO:0000242 xref: FMA:83689 ! Cervical mucus xref: MESH:A12.200.503.339 ! cervix mucus is_a: UBERON:0000912 {source="FMA"} ! mucus [Term] id: UBERON:0012249 alt_id: UBERON:0010182 name: ectocervix def: "The part of the cervix uteri that protrudes into the vagina and is lined with stratified squamous epithelium." [BTO:0001850, Wikipedia:Vaginal_portion_of_cervix] comment: AO notes: distinction between two FMA classes not clear - we merge them here synonym: "ectocervix" EXACT [BTO:0001850] synonym: "exocervix" RELATED [BTO:0001850] synonym: "portio vaginalis cervicis" EXACT LATIN [BTO:0001850] synonym: "portio vaginalis" EXACT [] synonym: "vaginal part of cervix" EXACT [FMA:77056] synonym: "ectocervix" EXACT [FMA:86484] synonym: "uterine ectocervix" EXACT [CALOHA:TS-1098] intersection_of: UBERON:0000064 ! organ part intersection_of: distal_part_of UBERON:0000002 ! uterine cervix relationship: proximal_to UBERON:0000996 ! vagina relationship: part_of UBERON:0000002 {source="BTO"} ! uterine cervix relationship: has_part UBERON:0010304 ! nonkeratinizing stratified squamous epithelium xref: BTO:0001850 ! portio vaginalis cervicis xref: FMA:86484 ! ectocervix xref: FMA:77056 ! vaginal part of cervix xref: ncithesaurus:Ectocervix ! ectocervix xref: SCTID:264459002 ! Entire ectocervix xref: CALOHA:TS-1098 ! Uterine ectocervix xref: UMLS:C0227829 [Term] id: UBERON:0000458 name: endocervix def: "1. The mucous membrane lining the canal of the cervix uteri. 2. The region of the opening of the uterine cervix into the uterine cavity." [BTO:0003002] xref: BTO:0003002 xref: FMA:86485 ! Endocervix xref: ncithesaurus:Endocervix intersection_of: UBERON:0000064 ! organ part intersection_of: proximal_part_of UBERON:0000002 ! uterine cervix relationship: has_part UBERON:0000485 ! simple columnar epithelium xref: SCTID:264460007 ! Entire endocervix xref: UMLS:C0227837 [Term] id: UBERON:0004801 name: cervix epithelium def: "An epithelium that is part of a uterine cervix [Automatically generated definition]." [OBOL:automatic] comment: Histology notes: The epithelium of the cervix is varied. The ectocervix (more distal, by the vagina) is composed of nonkeratinized stratified squamous epithelium. The endocervix (more proximal, within the uterus) is composed of simple columnar epithelium[http://en.wikipedia.org/wiki/Cervix#Histology] synonym: "cervical canal epithelial tissue" EXACT [OBOL:automatic] synonym: "cervical canal epithelium" EXACT [OBOL:automatic] synonym: "cervix epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelium of cervix" EXACT [OBOL:automatic] synonym: "cervical epithelium" EXACT [BTO:0000241] xref: MA:0001724 ! cervix epithelium xref: BTO:0000241 ! cervical epithelium xref: EFO:0001913 ! cervix epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000002 ! part_of uterine cervix xref: ncithesaurus:Cervix_Epithelium ! Cervix Epithelium xref: UMLS:C1711358 [Term] id: UBERON:0012250 ! cervix glandular epithelium name: cervix glandular epithelium comment: Histology notes: The “glandular” or columnar epithelium of the cervix is located cephalad to the squamocolumnar junction. It covers a variable amount of the ectocervix and lines the endocervical canal. It is comprised of a single layer of mucin-secreting cells. The epithelium is thrown into longitudinal folds and invaginations that make up the so-called endocervical glands (they are not true glands). These infolding crypts and channels make the cytologic and colposcopic detection of neoplasia less reliable and more problematic. The complex architecture of the endocervical glands gives the columnar epithelium a papillary appearance through the colposcope and a grainy appearance upon gross visual inspection. The single cell layer allows the coloration of the underlying vasculature to be seen more easily. Therefore, the columnar epithelium appears more red in comparison with the more opaque squamous epithelium.[http://www.asccp.org/practicemanagement/cervix/histologyofthenormalcervix/tabid/5842/default.aspx] synonym: "cervix columnar epithelium" RELATED [] intersection_of: UBERON:0006799 ! glandular epithelium intersection_of: part_of UBERON:0000002 ! uterine cervix xref: ncithesaurus:Cervix_Columnar_Epithelium ! cervix glandular epithelium xref: UMLS:C1707350 [Term] id: UBERON:0006922 ! cervix squamous epithelium name: cervix squamous epithelium def: "The squamous epithelium of the cervical portio is similar to that of the vagina, except that it is generally smooth and lacks rete pegs. Colposcopically, it appears featureless except for a fine network of vessels which is sometimes visible. The relative opacity and pale pink coloration of the squamous epithelium derives from its multi-layered histology and the location of its supporting vessels below the basement membrane." [http://www.asccp.org/practicemanagement/cervix/histologyofthenormalcervix/tabid/5842/default.aspx] xref: MA:0001725 ! cervix squamous epithelium is_a: UBERON:0010304 ! nonkeratinizing stratified squamous epithelium intersection_of: UBERON:0006914 ! squamous epithelium intersection_of: part_of UBERON:0000002 ! part_of uterine cervix xref: ncithesaurus:Cervix_Squamous_Epithelium ! Cervix Squamous Epithelium xref: UMLS:C1707351 [Term] id: UBERON:0012251 name: ectocervical epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0012249 ! ectocervix synonym: "exocervical epithelium" EXACT [] xref: SCTID:361376000 ! Entire exocervical epithelium [Term] id: UBERON:0012252 name: endocervical epithelium synonym: "endocervical glandular epithelium" EXACT [] is_a: UBERON:0006799 ! glandular epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000458 ! endocervix xref: SCTID:362256006 ! Entire endocervical epithelium xref: ncithesaurus:Endocervical_Glandular_Epithelium ! endocervical glandular epithelium [Term] id: UBERON:0012253 name: cervical squamo-columnar junction def: "Region of cervical epithelium where columnar epithelium of endocervic and the stratified non-keratinising squamous epithelium of the ectocervic meet" [http://www.asccp.org/practicemanagement/cervix/histologyofthenormalcervix/tabid/5842/default.aspx] comment: Site of 90% of lower genital tract neoplasia. This junction is presumed, but not proven, to be the embryologic junction of the Müllerian and urogenital sinus epithelia. synonym: "squamocolumnar junction" BROAD [] synonym: "squamocolumnar junction of uterine cervix" EXACT [] synonym: "squamo-columnar junction of uterine cervix" EXACT [] xref: SCTID:280451001 ! Entire squamocolumnar junction of uterine cervix xref: ncithesaurus:Squamocolumnar_Junction ! squamocolumnar junction intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000002 ! part_of uterine cervix intersection_of: continuous_with UBERON:0012250 ! cervix glandular epithelium intersection_of: continuous_with UBERON:0006922 ! cervix squamous epithelium [Term] id: UBERON:0002368 ! endocrine gland name: endocrine gland def: "Endocrine glands are glands of the endocrine system that secrete their products, hormones, directly into the blood rather than through a duct. The main endocrine glands include the pituitary gland, pancreas, ovaries, testes, thyroid gland, and adrenal glands. The hypothalamus is a neuroendocrine organ. Other organs which are not so well known for their endocrine activity include the stomach, which produces such hormones as ghrelin[WP]." [Wikipedia:Endocrine_gland] subset: uberon_slim synonym: "ductless gland" RELATED [Wikipedia:Ductless_gland] synonym: "ductless gland" EXACT [AEO:0000098] synonym: "glandula endocrina" EXACT [] xref: FMA:9602 ! Endocrine gland xref: GAID:335 ! endocrine gland xref: MA:0002563 ! endocrine gland xref: OpenCyc:Mx4rvbkiRZwpEbGdrcN5Y29ycA xref: ncithesaurus:Endocrine_Gland ! Endocrine Gland xref: BTO:0001488 ! endocrine gland xref: OpenCyc:Mx4rvbkiRZwpEbGdrcN5Y29ycA ! endocrine gland xref: EHDAA2:0003098 ! ductless gland xref: AEO:0000098 ! ductless gland xref: MESH:A06.407 ! endocrine gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000949 ! endocrine system relationship: capable_of GO:0060986 ! endocrine hormone secretion xref: SCTID:40818001 ! Entire endocrine gland subset: organ_slim synonym: "glandulae endocrinae" RELATED LATIN [Wikipedia:Endocrine_gland] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Illu_endocrine_system.png xref: UMLS:C0014133 [Term] id: UBERON:0010133 name: neuroendocrine gland xref: MA:0000720 ! neuroendocrine gland intersection_of: UBERON:0002368 ! endocrine gland intersection_of: part_of UBERON:0001016 ! nervous system relationship: has_part CL:0000165 ! neuroendocrine cell def: "An endocrine gland that is part of a nervous system." [OBOL:automatic] [Term] id: UBERON:0009113 ! thymic region name: thymic region is_a: UBERON:0000475 ! organism subdivision relationship: overlaps UBERON:0000974 {source="EHDAA2-modified"} ! neck relationship: overlaps UBERON:0003728 ! mediastinum relationship: overlaps UBERON:0002224 {source="MA-modified"} ! thoracic cavity relationship: part_of UBERON:0000153 ! anterior region of body [Term] id: UBERON:0009114 name: cervical thymus def: "A mature thymus that is entirely part of the cervical region." [UBERON:cjm] comment: A cervical thymus is a pathological structure in a human - it can form during the migration of the thymus to its location in the mediastinum. Some mice have a cervical thymus. There are examples of cervical thymi in marsupials and prosimians[ISBN-10:0781714125] intersection_of: UBERON:0002370 ! thymus intersection_of: part_of UBERON:0000974 ! neck relationship: present_in_taxon NCBITaxon:9263 ! Metatheria subset: organ_slim [Term] id: UBERON:0009115 name: thoracic thymus def: "A mature thymus that is entirely part of thoracic region." [UBERON:cjm] intersection_of: UBERON:0002370 ! thymus intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: located_in UBERON:0002224 {source="MA-modified"} ! thoracic cavity subset: organ_slim [Term] id: UBERON:0009116 name: thymoid def: "A thymus-like lympho-epithelial structures, in the tips of the gill filaments and the neighbouring secondary lamellae (both within the gill basket) of lamprey larvae." [PMID:21293377] comment: Genes: FOXN1 is_a: UBERON:0002368 ! endocrine gland relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0002405 ! immune system relationship: part_of UBERON:0009101 ! ammocoete relationship: has_part PR:000007636 {source="PMID:21293377"} ! forkhead box protein N1 relationship: part_of UBERON:0009119 ! branchial basket subset: organ_slim [Term] id: UBERON:0002370 name: thymus def: "Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop." [NLM:thymus, Wikipedia:Thymus] comment: check - a subtype of gland? not in GO. NCIT has thymus and thymus gland. EHDAA2 has ductless gland. subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "thymus gland" EXACT [] xref: BTO:0001374 xref: EFO:0000860 ! thymus xref: EHDAA:9119 ! thymus xref: FMA:9607 ! Thymus xref: GAID:464 ! thymus gland xref: VHOG:0000253 ! thymus xref: MA:0000142 ! thymus xref: MAT:0000080 ! thymus xref: MIAA:0000080 ! thymus xref: TAO:0001078 ! thymus xref: XAO:0000163 ! thymus xref: ZFA:0001078 ! thymus xref: ncithesaurus:Thymus_Gland ! Thymus Gland xref: OpenCyc:Mx4rvpIympwpEbGdrcN5Y29ycA ! thymus xref: EHDAA2:0002017 ! thymus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Illu_thymus.jpg/200px-Illu_thymus.jpg xref: EMAPA:18768 ! thymus xref: MESH:A06.407.850 ! thymus gland (also: UBERON:0003483 'thymus lymphoid tissue') xref: EV:0100138 ! thymus is_a: UBERON:0002368 {source="EHDAA2"} ! endocrine gland relationship: part_of UBERON:0009113 ! thymic region relationship: part_of UBERON:0002390 {source="FMA"} ! hematopoietic system relationship: part_of UBERON:0000949 {source="XAO"} ! endocrine system relationship: part_of UBERON:0002405 {source="XAO"} ! immune system relationship: develops_from UBERON:0005562 {source="ZFA"} ! thymus primordium relationship: has_part CL:0000827 {source="ZFA"} ! pro-T cell relationship: site_of GO:0030217 ! T cell differentiation relationship: only_in_taxon NCBITaxon:7776 {source="multiple sources - true thymus appears in jawed vertebrates"} ! Gnathostomata xref: AAO:0010548 ! thymus gland xref: SCTID:118507000 ! Entire thymus subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Illu_thymus.jpg property_value: external_definition "Anatomical structure which originates as several paired thickenings on the dorsal side of the pharyngeal pouches and secretes thymosin.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010548", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: homology_notes "A thymus develops in all vertebrates from the endodermal epithelium of certain pharyngeal pouches and from the adjacent ectodermal epithelium. In fishes, all the pouches, or the first four, contribute to thymus formation, but in tetrapods, the number is more restricted. In mammals, only the third and fourth are involved, and the contribution of the third is by far the greater.[well established][VHOG]" xsd:string {external_class="VHOG:0000253", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.558", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "thymic" xsd:string xref: UMLS:C0040113 [Term] id: UBERON:0002371 name: bone marrow def: "flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells[WP]." [Wikipedia:Bone_marrow] comment: TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs subset: uberon_slim synonym: "anterior kidney" RELATED [] synonym: "head kidney" BROAD [] synonym: "kidney marrow" RELATED [] synonym: "medulla ossea" EXACT [] synonym: "medulla of bone" RELATED [BTO:0000141] synonym: "medulla ossium" RELATED [BTO:0000141] xref: BTO:0000141 ! bone marrow xref: BTO:0000829 ! marrow xref: EFO:0000868 ! bone marrow xref: FMA:9608 ! Bone marrow xref: GAID:1287 ! bone marrow xref: galen:BoneMarrow xref: VHOG:0001218 ! bone marrow xref: MA:0000134 ! bone marrow xref: MAT:0000084 ! bone marrow xref: MIAA:0000084 ! bone marrow xref: OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA xref: XAO:0000123 ! bone marrow xref: ncithesaurus:Bone_Marrow ! Bone Marrow xref: OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA ! bone marrow xref: MESH:A15.382.216 ! bone marrow xref: EV:0100046 ! bone marrow is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001474 ! bone element relationship: part_of UBERON:0002390 ! hematopoietic system relationship: site_of GO:0030097 ! hemopoiesis relationship: part_of UBERON:0002405 ! immune system xref: AAO:0011007 ! bone marrow xref: SCTID:421320006 ! Structure of marrow of a bone synonym: "medulla ossium" RELATED LATIN [Wikipedia:Bone_marrow] xref: http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg property_value: homology_notes "The bone marrow is the hematopoietic organ in all vertebrates but fishes, in which hematopoiesis occurs in the kidney.[well established][VHOG]" xsd:string {external_class="VHOG:0001218", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V\, Blood Cells and Blood Cell Development in the Animal Kingdom. Annual Review of Cell and Developmental Biology (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0005953 [Term] id: UBERON:0000332 name: yellow bone marrow def: "bone marrow in which the fat cells predominate in the meshes of the reticular network." [http://medical-dictionary.thefreedictionary.com/Yellow+Marrow] synonym: "fat marrow" RELATED [BTO:0000635] synonym: "medulla ossium flava" EXACT LATIN [BTO:0000635] synonym: "yellow marrow" RELATED [BTO:0000635] xref: BTO:0000635 xref: FMA:74596 ! Yellow bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: composed_primarily_of CL:0000136 ! fat cell xref: SCTID:5023006 ! Structure of yellow bone marrow xref: SCTID:328639002 ! All yellow bone marrow [Term] id: UBERON:0000361 name: red bone marrow def: "The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream." [http://medical-dictionary.thefreedictionary.com/red+marrow] synonym: "medulla ossium rubra" EXACT LATIN [BTO:0001160] synonym: "red marrow" RELATED [BTO:0001160] xref: BTO:0001160 xref: FMA:74595 ! Red bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: composed_primarily_of CL:0000988 ! hematopoietic cell xref: SCTID:75330005 ! Structure of red bone marrow xref: SCTID:328538003 ! All red bone marrow [Term] id: UBERON:0007132 ! head kidney name: head kidney def: "The zebrafish head kidney consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis." [ZFIN:ZDB-PUB-040923-1, doi:10.1242/dev.00427] comment: in GO, head kidney isa pronephros. Modified the ZFA relationships - the HK is derived from the anterior part of the pronephros and persists until adulthood synonym: "anterior kidney" EXACT [ZFA:0000669] synonym: "kidney marrow" EXACT [ZFA:0000669] xref: TAO:0000669 ! head kidney xref: ZFA:0000669 ! head kidney xref: BTO:0005189 ! head kidney is_a: UBERON:0003103 ! compound organ relationship: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0000949 ! endocrine system relationship: part_of UBERON:0002390 ! hematopoietic system relationship: site_of GO:0030097 ! hemopoiesis relationship: develops_from UBERON:0002120 {source="cjm"} ! pronephros subset: organ_slim property_value: external_definition "The zebrafish head kidney consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis. Davidson and Zon 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000669", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0009099 name: typhlosole def: "an invagination of the intestinal epithelium that emanates from a lamina of mesenchymal cells located between the dorsal aorta and the upper intestine and constitute one of the two principal hematopoietic organs at the ammocoete stage of development." [Wikipedia:Typhlosole, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093943/] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0001277 ! intestinal epithelium relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0009101 ! ammocoete relationship: develops_from UBERON:0003104 ! mesenchyme [Term] id: UBERON:0009100 name: nephric fold def: "." [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093943/] comment: Lymphocytes are also abundant in the lamprey kidney, where large populations are intermingled around the renal tubules is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0009101 ! ammocoete [Term] id: UBERON:0009101 ! ammocoete name: ammocoete def: "lamprey at larval stage" [] is_a: UBERON:0002548 ! larva relationship: only_in_taxon NCBITaxon:7746 ! Petromyzontidae [Term] id: UBERON:0009102 name: supraneural body def: "One of the primary immunological organs of the adult lamprey is the supraneural body. This structure lies dorsal to spinal column and becomes heavily populated with lymphocytes following after immune challenge [13–15]. The supraneural body from hematopoietically stimulated lampreys appears to be histologically-similar to ‘bone marrow’ in higher vertebrates and contains all blood cell lineages and their precursors, including lymphocytes at all stages of maturity[16]." [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823822/#R16] synonym: "pro-vertebral arch" EXACT [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093943/] synonym: "dorsal fat body" EXACT [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2093943/] is_a: UBERON:0000062 ! organ relationship: only_in_taxon NCBITaxon:7746 ! Petromyzontidae relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0002405 ! immune system subset: organ_slim [Term] id: UBERON:0004461 ! musculature of head name: musculature of head def: "A musculature that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "head musculature" EXACT [FMA:71287] synonym: "muscle group of head" EXACT [FMA:71287] synonym: "muscles of head" EXACT [FMA:71287] xref: FMA:71287 ! Musculature of head intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000033 ! part_of head synonym: "musculi capitis" EXACT LATIN [FMA:TA, FMA:71287] synonym: "set of muscles of head" EXACT [FMA:71287] [Term] id: UBERON:0010959 ! craniocervical muscle name: craniocervical muscle synonym: "muscle of head or neck" EXACT [] synonym: "muscle of head and neck" RELATED [] intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0007811 ! craniocervical region xref: ncithesaurus:Head_and_Neck_Muscle ! head and neck muscle def: "A muscle organ that is part of a craniocervical region." [OBOL:automatic] xref: UMLS:C0448281 [Term] id: UBERON:0002376 name: muscle of head def: "Any muscle that is part of a head[Automatically generated definition]." [OBOL:automatic] comment: TODO - check ZFA subset: uberon_slim subset: vertebrate_core synonym: "head muscle" EXACT [MA:0000578] synonym: "cephalic musculature" EXACT [] synonym: "head muscles" RELATED [] synonym: "musculus caput" EXACT [] synonym: "adult head muscle organ" EXACT [OBOL:automatic] synonym: "head muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of adult head" EXACT [OBOL:automatic] synonym: "muscle organ of head" EXACT [OBOL:automatic] synonym: "cephalic muscle" EXACT [ZFA:0001652] synonym: "cranial muscle " RELATED [ZFA:0001652] xref: BTO:0000021 xref: FMA:9616 ! Muscle of head xref: MA:0000578 ! head muscle xref: TAO:0000328 ! cephalic musculature xref: ZFA:0000328 ! cephalic musculature xref: ZFA:0001652 ! head muscle xref: AAO:0000107 ! cranial muscles xref: EMAPA:18171 ! cranial muscle xref: EFO:0003524 ! cephalic musculature is_a: UBERON:0010959 ! craniocervical muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0004461 ! musculature of head relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002", gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! neural crest relationship: develops_from UBERON:0006904 {source="EHDAA2-abduced"} ! head mesenchyme from mesoderm xref: EHDAA2:0000322 ! cranial muscle system [Term] id: UBERON:0002377 name: muscle of neck def: "Muscle organ which is a part of the neck. Examples: platysma, sternocleidomastoid, cricothyroid muscle.[FMA]" [FMA:9617] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "neck muscle" EXACT [] synonym: "muscle organ of neck" EXACT [OBOL:automatic] synonym: "muscle organ of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) muscle organ" EXACT [OBOL:automatic] synonym: "neck muscle organ" EXACT [OBOL:automatic] xref: FMA:9617 ! Muscle of neck xref: GAID:149 ! neck muscle xref: MA:0000587 ! neck muscle xref: ncithesaurus:Neck_Muscle ! Neck Muscle xref: MESH:A02.633.567.650 ! neck muscle (also: UBERON:0004465 'musculature of neck') is_a: UBERON:0010959 ! craniocervical muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000974 ! neck xref: UMLS:C0027532 [Term] id: UBERON:0002343 name: abdomen musculature def: "Set of all muscles in abdomen." [OBOL:automatic] comment: note distinction between abdomen muscle and abdomen musculature subset: vertebrate_core synonym: "abdominal musculature" EXACT [] synonym: "musculature of abdomen" EXACT [] synonym: "musculature of abdominal wall" EXACT [FMA:86917] synonym: "muscle group of abdomen" EXACT [FMA:71294] synonym: "muscles of abdomen" EXACT [FMA:71294] xref: FMA:86917 ! Musculature of abdomen xref: TAO:0001327 ! abdominal musculature xref: ZFA:0001327 ! abdominal musculature xref: FMA:71294 ! Set of muscles of abdomen is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000916 ! abdomen synonym: "set of muscles of abdomen" EXACT [FMA:71294] [Term] id: UBERON:0003833 name: abdominal segment muscle def: "A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of abdominal segment of trunk" EXACT [OBOL:automatic] xref: MA:0000527 ! abdominal segment muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0002378 name: muscle of abdomen def: "Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis." [Wikipedia:Abdominal_muscle] subset: uberon_slim synonym: "abdomen muscle" EXACT [] synonym: "abdominal muscle" EXACT [] synonym: "abdominal wall muscle" EXACT [] synonym: "abdomen muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of abdomen" EXACT [OBOL:automatic] xref: BTO:0001261 xref: FMA:9620 ! Muscle of abdomen xref: GAID:89 ! abdominal muscle xref: MA:0000520 ! abdomen muscle xref: ncithesaurus:Abdominal_Muscle ! Abdominal Muscle xref: OpenCyc:Mx4rvlygNJwpEbGdrcN5Y29ycA ! abdominal muscle xref: MESH:A02.633.567.050 ! abdominal muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0003697 ! abdominal wall xref: SCTID:361352008 ! Entire abdominal wall muscle xref: UMLS:C0000739 [Term] id: UBERON:0001339 name: ischiocavernosus muscle def: "The ischiocavernosus muscle is a muscle just below the surface of the perineum, present in both men and women. [WP,unvetted]." [Wikipedia:Ischiocavernosus_muscle] subset: uberon_slim synonym: "erector penis" RELATED [Wikipedia:Ischiocavernosus_muscle] synonym: "ischiocavernosi" RELATED [Wikipedia:Ischiocavernosus_muscle] synonym: "ischiocavernosus" RELATED [Wikipedia:Ischiocavernosus_muscle] synonym: "ischiocavernous muscle" RELATED [Wikipedia:Ischiocavernosus_muscle] synonym: "ishiocavernosus" RELATED [Wikipedia:Ischiocavernosus_muscle] synonym: "ishiocavernosus muscle" RELATED [Wikipedia:Ischiocavernosus_muscle] synonym: "musculus ishiocavernosus" EXACT LATIN [Wikipedia:Ischiocavernosus_muscle] xref: FMA:19730 ! Ischiocavernosus xref: MA:0002330 ! ischiocavernosus xref: ncithesaurus:Ischiocavernosus ! Ischiocavernosus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ischiocavernosus-female.png/200px-Ischiocavernosus-female.png is_a: UBERON:0002379 ! perineal muscle relationship: has_muscle_origin UBERON:0001274 ! ischium subset: organ_slim xref: SCTID:244975004 ! Entire ischiocavernosus muscle xref: UMLS:C0224401 [Term] id: UBERON:0002380 name: trapezius def: "In human anatomy, the trapezius is a large superficial muscle that extends longitudinally from the occipital bone to the lower thoracic vertebrae and laterally to the spine of the scapula (shoulder blade). Its functions are to move the scapulae and support the arm. The trapezius has three functional regions: the superior region (descending part), which supports the weight of the arm; the intermediate region (transverse part), which retracts the scapulae; and the inferior region (ascending part), which medially rotates and depresses the scapulae. [WP,unvetted]." [Wikipedia:Trapezius_muscle] subset: uberon_slim synonym: "trapezius muscle" EXACT [] xref: FMA:9626 ! Trapezius xref: VHOG:0000834 ! trapezius xref: MA:0002398 ! trapezius xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/60/Trapezius.png/200px-Trapezius.png xref: EMAPA:18183 ! trapezius is_a: UBERON:0001482 ! muscle of shoulder relationship: develops_from UBERON:0010955 ! trapezius pre-muscle mass xref: ncithesaurus:Trapezius_Muscle ! Trapezius Muscle xref: SCTID:181740005 ! Entire trapezius muscle relationship: has_muscle_antagonist UBERON:0001112 {source="dbpedia"} ! latissimus dorsi relationship: has_muscle_antagonist UBERON:0001125 {source="dbpedia"} ! serratus anterior synonym: "musculus trapezius" RELATED LATIN [Wikipedia:Trapezius_muscle] relationship: has_muscle_insertion UBERON:0007173 {source="dbpedia", notes="posterior border of the lateral third of the clavicle acromion process and spine of scapula"} ! lateral border of scapula relationship: has_muscle_insertion UBERON:0002497 {source="dbpedia", notes="posterior border of the lateral third of the clavicle acromion process and spine of scapula"} ! acromion relationship: has_muscle_origin UBERON:0000351 {source="dbpedia", notes="external occipital protuberance nuchal ligament medial superior nuchal line spinous processes of vertebrae C7-T12"} ! nuchal ligament relationship: has_muscle_origin UBERON:0001076 {source="dbpedia", notes="external occipital protuberance nuchal ligament medial superior nuchal line spinous processes of vertebrae C7-T12"} ! spinous process of vertebra xref: http://upload.wikimedia.org/wikipedia/commons/6/60/Trapezius.png property_value: homology_notes "The sternomastoid and the three parts of the trapezius are branchiomeric muscles that have secondarily acquired an attachment to the pectoral girdle. They evolved from the fish cucullaris.[well established][VHOG]" xsd:string {external_class="VHOG:0000834", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.345", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0224361 [Term] id: UBERON:0010955 ! trapezius pre-muscle mass name: trapezius pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle xref: EHDAA2:0002079 ! trapezius pre-muscle mass [Term] id: UBERON:0010989 name: transverospinalis pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group xref: EHDAA2:0002076 ! transverospinalis pre-muscle mass [Term] id: UBERON:0010990 name: transversospinales muscle def: "The transversospinal muscles are a group of muscles of the human back. Their combined action is rotation and extension of the vertebral column. They include: semispinalis, spanning 4-6 vertebral segments semispinalis dorsi semispinalis cervicis semispinalis capitis multifidus, spanning 2-4 vertebral segments rotatores, spanning 1-2 vertebral segments rotatores cervicis rotatores thoracis rotatores lumborum" [Wikipedia:Transversospinales_muscles] synonym: "deep dorsal muscles" RELATED [Wikipedia:Transversospinales_muscles] synonym: "transversospinal group of muscles" RELATED [Wikipedia:Transversospinales_muscles] synonym: "musculi transversospinales" RELATED [FMA:TA] synonym: "transverospinalis" EXACT [EHDAA2:0002075] synonym: "transversospinales" RELATED [FMA:71304] synonym: "transversospinales muscle group" RELATED [FMA:71304] is_a: UBERON:0003897 {source="EHDAA2"} ! axial muscle relationship: develops_from UBERON:0010989 {source="EHDAA2"} ! transverospinalis pre-muscle mass xref: EHDAA2:0002075 ! transverospinalis xref: FMA:71304 ! transversospinales muscle group xref: SCTID:244866002 ! Entire transversospinalis muscle xref: EHDAA:9465 ! transverospinalis synonym: "musculi transversospinales" RELATED LATIN [Wikipedia:Transversospinales_muscles] xref: http://upload.wikimedia.org/wikipedia/commons/7/7f/Gray384.png [Term] id: UBERON:0002382 name: rectus abdominis muscle def: "The rectus abdominis muscle is a paired muscle running vertically on each side of the anterior wall of the human abdomen (and in some other animals). There are two parallel muscles, separated by a midline band of connective tissue called the linea alba (white line). It extends from the pubic symphysis/pubic crest inferiorly to the xiphisternum/xiphoid process and lower costal cartilages (5–7) superiorly. It is contained in the Rectus sheath. The rectus is usually crossed by three fibrous bands licked by the tendinous inscriptions. While the 'sixpack' is by far the most common configuration of the muscle bellies of the rectus, there exist rare anatomic variations which result in the appearance of eight ('eightpack'), ten, or—even rarer—asymmetrically arranged segments. All these variations are functionally equivalent. [WP,unvetted]." [Wikipedia:Rectus_abdominis_muscle] synonym: "m. rectus abdominis" EXACT [AAO:0010789] synonym: "musculus rectus abdominis" EXACT [AAO:0010789] synonym: "rectus abdominis" EXACT [MA:0002364] synonym: "six pack" RELATED [] subset: uberon_slim xref: EHDAA:8252 ! rectus abdominis xref: FMA:9628 ! Rectus abdominis xref: GAID:142 ! rectus abdominis xref: VHOG:0000863 ! rectus abdominis xref: MA:0002364 ! rectus abdominis xref: ncithesaurus:Rectus_Abdominis ! Rectus Abdominis xref: EHDAA2:0001595 ! rectus abdominis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/95/Rectus_abdominis.png/200px-Rectus_abdominis.png xref: EMAPA:18164 ! rectus abdominis xref: MESH:A02.633.567.050.800 ! rectus abdominis xref: SCTID:256672008 ! Entire rectus abdominis muscle is_a: UBERON:0002378 ! muscle of abdomen relationship: has_muscle_origin UBERON:0007832 ! pelvic girdle skeleton relationship: has_muscle_insertion UBERON:0000975 ! sternum relationship: part_of UBERON:0008777 {source="XAO"} ! hypaxial musclulaturex relationship: part_of UBERON:0006635 {source="VHOG"} ! anterior abdominal wall subset: organ_slim xref: AAO:0010789 ! m. rectus abdominis xref: XAO:0004128 ! rectus abdominus xref: UMLS:C0206066 [Term] id: UBERON:0002383 name: supraspinatus muscle def: "The supraspinatus is a relatively small muscle of the upper limb that takes its name from its origin from the supraspinous fossa superior to the spine of the scapula. It is one of the four rotator cuff muscles and also abducts the arm at the shoulder. The spine of the scapula separates the supraspinatus muscle from the infraspinatus muscle, which originates below the spine. [WP,unvetted]." [Wikipedia:Supraspinatus_muscle] synonym: "musculus supraspinatus" EXACT LATIN [Wikipedia:Supraspinatus_muscle] subset: uberon_slim xref: EHDAA:8319 ! supraspinatus xref: FMA:9629 ! Supraspinatus xref: VHOG:0000848 ! supraspinatus xref: MA:0002389 ! supraspinatus synonym: "supraspinatus" EXACT [MA:0002389] xref: ncithesaurus:Supraspinatus ! Supraspinatus xref: EHDAA2:0001967 ! supraspinatus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/99/Arm_muscles_back_numbers.png/200px-Arm_muscles_back_numbers.png xref: EMAPA:18182 ! supraspinatus is_a: UBERON:0001482 ! muscle of shoulder relationship: part_of UBERON:0003683 {source="Wikipedia"} ! rotator cuff relationship: has_muscle_insertion UBERON:0011187 {source="dbpedia", notes="middle facet of greater tubercle of the humerus"} ! greater tubercle of humerus relationship: has_muscle_origin UBERON:0006849 {source="dbpedia", notes="supraspinous fossa of the scapula"} ! scapula xref: SCTID:181626001 ! Entire supraspinatus xref: UMLS:C0584869 [Term] id: UBERON:0002384 name: connective tissue def: "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibres and ground substance." [VSAO:0000017] comment: AO notes: MA also has set of connective tissues subset: uberon_slim subset: vertebrate_core synonym: "portion of connective tissue" EXACT [FMA:9640] synonym: "textus connectivus" EXACT [] synonym: "Bindegewebe" RELATED [BTO:0000421] xref: AAO:0000098 ! connective_tissue xref: BTO:0000421 xref: FMA:9640 ! Portion of connective tissue xref: GAID:100 ! connective tissue xref: galen:ConnectiveTissue xref: MA:0000011 ! connective tissue xref: MAT:0000301 ! connective tissue xref: MIAA:0000301 ! connective tissue xref: ncithesaurus:Connective_Tissue xref: OpenCyc:Mx4rv-aBgZwpEbGdrcN5Y29ycA xref: XAO:0001017 ! portion of connective tissue xref: ZFA:0001632 ! portion of connective tissue xref: EFO:0000952 ! connective tissue xref: OpenCyc:Mx4rv-aBgZwpEbGdrcN5Y29ycA ! connective tissue xref: VSAO:0000017 ! portion of connective tissue is_a: UBERON:0000479 ! portion of tissue xref: SCTID:361919005 ! Entire connective tissue xref: TAO:0001641 ! portion of connective tissue xref: MESH:A10.165 ! connective tissue property_value: external_definition "One of the four types of tissue in traditional classifications. It is largely a category of exclusion rather than one with a precise definition, but there are certain characteristics shared by all or most tissues in this category, such as involvement in structure and support, derived from mesoderm, and characterized largely by the traits of non-living tissue.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000098", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000017", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170"} property_value: external_definition "Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001641", date_retrieved="2012-08-14", source="TAO:wd"} xref: UMLS:C0009780 [Term] id: UBERON:0007845 name: regular connective tissue def: "Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue." [FMA:20103] comment: Editor notes: the connective tissue hierarchy largely follows FMA with definitions from VSAO. Note that in FMA, loose-CT is irregular-CT. This means regular-CT is necessarily equivalent to dense-regular-CT (assuming a JEPD classification). xref: FMA:20103 ! regular connective tissue is_a: UBERON:0002384 {source="FMA"} ! connective tissue [Term] id: UBERON:0011821 name: irregular connective tissue def: "Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium." [FMA:20107] is_a: UBERON:0002384 {source="FMA"} ! connective tissue disjoint_from: UBERON:0007845 ! regular connective tissue xref: FMA:20107 ! irregular connective tissue [Term] id: UBERON:0011823 name: dense connective tissue def: "Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets" [Wikipedia:Dense_connective_tissue] is_a: UBERON:0002384 ! connective tissue xref: AAO:0000121 ! dense connective tissue xref: ncithesaurus:Dense_Connective_Tissue ! dense connective tissue property_value: external_definition "Connective tissue in which the fibrous component predominates. The cells, ground substance, and tissue fluid represent a minor component[NCIT]" xsd:string {ontology="NCIT", external_class="ncithesaurus:Dense_Connective_Tissue", date_retrieved="2012-08-29"} xref: UMLS:C1511770 [Term] id: UBERON:0011824 name: fibrous connective tissue is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue xref: FMA:75634 ! fibrous connective tissue xref: SCTID:363130003 ! Fibrous connective tissue [Term] id: UBERON:0011825 name: loose connective tissue def: "Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue." [FMA:19783, Wikipedia:Loose_connective_tissue] is_a: UBERON:0011821 {source="FMA"} ! irregular connective tissue disjoint_from: UBERON:0011823 ! dense connective tissue xref: FMA:19783 ! loose connective tissue xref: ncithesaurus:Loose_Connective_Tissue ! Loose Connective Tissue xref: UMLS:C1253917 [Term] id: UBERON:0007846 name: dense regular connective tissue def: "Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts)[VSAO]" [VSAO:0000050, Wikipedia:Dense_regular_connective_tissue] synonym: "dense fibrous connective tissue" EXACT [FMA:64781] synonym: "dense regular collagenous connective tissue" EXACT [FMA:64781] synonym: "typus regularis (textus connectivus collagenosus compactus)" EXACT [FMA:64781] synonym: "dense regular collagenous tissue" EXACT [FMA:64781] synonym: "regular dense connective tissue" EXACT [] xref: FMA:64781 ! dense regular collagenous tissue xref: VSAO:0000050 ! dense regular connective tissue is_a: UBERON:0007845 {source="FMA"} ! regular connective tissue is_a: UBERON:0011823 {source="ncithesaurus"} ! dense connective tissue relationship: composed_primarily_of GO:0005581 ! collagen xref: ncithesaurus:Regular_Dense_Connective_Tissue ! Regular Dense Connective Tissue xref: SCTID:22560007 ! Dense fibrous connective tissue xref: XAO:0004030 ! dense regular connective tissue property_value: external_definition "Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts).[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000050", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170"} property_value: external_definition "Regular connective tissue, the intercellular matrix of which consists predominantly of collagen fiber bundles arranged in parallel arrays.[FMA]" xsd:string {ontology="FMA", external_class="FMA:64781", date_retrieved="2012-08-29"} xref: UMLS:C0225333 [Term] id: UBERON:0011822 name: dense irregular connective tissue def: "Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium." [FMA:20109, Wikipedia:Dense_irregular_connective_tissue] synonym: "typus irregularis (textus connectivus collagenosus compactus)" EXACT [FMA:20109] synonym: "irregular dense connective tissue" EXACT [] is_a: UBERON:0011821 {source="FMA"} ! irregular connective tissue xref: FMA:20109 ! dense irregular connective tissue xref: ncithesaurus:Irregular_Dense_Connective_Tissue ! irregular dense connective tissue property_value: external_definition "Tissue characterized by a thick, random arrangement of collagen and elastin fibers with very few cells. The majority of the cells are fibroblasts, but mast cells and macrophages may also be seen. It is found in the dermis, periosteum, perichondrium, capsules of organs and sheaths of nerves and muscles[NCIT]" xsd:string {ontology="NCIT", external_class="ncithesaurus:Irregular_Dense_Connective_Tissue", date_retrieved="2012-08-29"} xref: UMLS:C0738366 [Term] id: UBERON:0002387 name: pes def: "distal portion of the hind limb, including tarsal region, metatarsal region and digits." [Wikipedia:Foot, Wikipedia:Pes_(anatomy)] comment: Editors note: consider renaming using less human-centric terminology subset: uberon_slim synonym: "pes" EXACT [UBERON:cjm] synonym: "terminal segment of free lower limb" EXACT [] synonym: "hind-paw" NARROW SENSU [EMAPA:17428] synonym: "hind paw" NARROW SENSU [EMAPA:17428, OBOL:automatic] synonym: "hind limb autopodium" RELATED [VHOG:0000350] synonym: "hindlimb autopod" EXACT [OBOL:automatic] synonym: "hindlimb autopodium" EXACT [OBOL:automatic] synonym: "hindlimb distal free limb segment" EXACT [OBOL:automatic] synonym: "foot" EXACT [MA:0000044] synonym: "hindfoot of quadruped" NARROW [] synonym: "hindfoot" NARROW [] synonym: "hind foot" NARROW [] xref: BTO:0000476 xref: FMA:9664 ! Foot xref: GAID:40 ! foot xref: galen:Foot xref: MA:0000044 ! foot xref: OpenCyc:Mx4rvVi-k5wpEbGdrcN5Y29ycA xref: EMAPA:17459 ! hind-paw xref: EHDAA2:0000546 ! foot region xref: ncithesaurus:Foot ! Foot xref: VHOG:0000350 ! hindlimb autopodium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ae/Male_Right_Foot_1.jpg/200px-Male_Right_Foot_1.jpg xref: MESH:A01.378.610.250 ! foot xref: EFO:0003065 ! foot intersection_of: UBERON:0002470 ! autopod region intersection_of: part_of UBERON:0002103 ! hindlimb relationship: develops_from UBERON:0006871 ! footplate xref: SCTID:302545001 ! Entire foot xref: http://upload.wikimedia.org/wikipedia/commons/a/ae/Male_Right_Foot_1.jpg property_value: has_relational_adjective "pedal" xsd:string xref: UMLS:C0016504 [Term] id: UBERON:0002389 name: manual digit alt_id: UBERON:0000028 def: "A digit that is part of a manus (hand)." [Wikipedia:Finger] subset: uberon_slim synonym: "digit of manus" EXACT [] synonym: "digitus manus" EXACT [] synonym: "forelimb digit" EXACT [] synonym: "fore digit" EXACT [AAO:0000857, XAO:0003036] synonym: "finger" EXACT [FMA:9666] synonym: "hand digit" EXACT [MA:0000041] xref: FMA:9666 ! Finger xref: GAID:57 ! finger xref: galen:Finger xref: MA:0000041 ! hand digit xref: AAO:0000857 ! fore digit xref: XAO:0003036 ! fore digit xref: OpenCyc:Mx4rvVi_f5wpEbGdrcN5Y29ycA xref: ncithesaurus:Finger ! Finger xref: OpenCyc:Mx4rvVi_f5wpEbGdrcN5Y29ycA ! finger xref: NIF_GrossAnatomy:nlx_anat_20090602 ! Finger xref: BTO:0004669 ! finger xref: EHDAA2:0000404 ! digital region xref: MESH:A01.378.800.667.430 ! finger intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0012141 {source="PHENOSCAPE:ni"} ! manual digitopodium region xref: SCTID:283992002 ! Entire digit of hand property_value: external_definition "One of the fingers of the manus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000857", date_retrieved="2012-06-20", source="AAO:LAP"} synonym: "digit of hand" EXACT [FMA:9666] xref: UMLS:C0016129 [Term] id: UBERON:0002391 name: lymph def: "Transudate contained in the lumen of lymphatic vessel[FMA]. Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system[WP]." [FMA:9671, Wikipedia:Lymph] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: ZFA:0005658 ! lymph xref: BTO:0000855 xref: EFO:0000871 ! lymph xref: ENVO:02000041 xref: FMA:9671 ! Lymph xref: GAID:1186 ! lymph xref: MA:0002520 ! lymph xref: MAT:0000055 ! lymph xref: MIAA:0000055 ! lymph xref: ncithesaurus:Lymph ! Lymph xref: galen:Lymph ! lymph xref: OpenCyc:Mx4rvpDOU5wpEbGdrcN5Y29ycA ! lymph xref: MESH:A12.207.630 ! lymph xref: EV:0100049 ! lymph is_a: UBERON:0000179 ! haemolymphatic fluid relationship: develops_from UBERON:0000913 ! interstitial fluid synonym: "lympha" RELATED LATIN [Wikipedia:Lymph] xref: http://upload.wikimedia.org/wikipedia/commons/1/19/Illu_lymph_capillary.png xref: VHOG:0001590 ! lymph xref: UMLS:C0024202 [Term] id: UBERON:0002396 name: vomer def: "." [Wikipedia:Vomer] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "vomer bone" EXACT [] xref: AAO:0000633 ! vomer xref: FMA:9710 ! Vomer xref: MA:0001496 ! vomer bone xref: OpenCyc:Mx4rv6jKWZwpEbGdrcN5Y29ycA xref: ZFA:0000308 ! prevomer xref: ncithesaurus:Vomer ! Vomer xref: OpenCyc:Mx4rv6jKWZwpEbGdrcN5Y29ycA ! vomer xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/77/Illu_facial_bones.jpg/200px-Illu_facial_bones.jpg is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: part_of UBERON:0011156 ! facial skeleton relationship: part_of UBERON:0012072 {source="Kardong", notes="palatal series"} ! palatal part of dermatocranium xref: SCTID:272678009 ! Entire vomer bone xref: TAO:0000308 ! vomer relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg property_value: external_definition "Paired, palatal bones of intramembranous origin that lie ventral to the olfactory region and help to floor the nasal capsules.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000633", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Dermal bone that underlies the mesethmoid and inserts in a fossa on the anteroventral surface of the parasphenoid.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000308", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps mesethmoid-vomer joint (TAO:0001680)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000308", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps autopalatine-vomer joint (TAO:0001784)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000308", date_retrieved="2012-08-14"} synonym: "prevomer" RELATED [TAO:0000308] property_value: external_comment "The vomer is paired in some taxa (e.g., Amia) while unpaired in others (e.g., teleosts).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000308", date_retrieved="2012-09-06", source="Curator"} property_value: homology_notes "In bony fish, the vomers are flattened, paired, bones forming the anterior part of the roof of the mouth, just behind the premaxillary bones. In many species, they have teeth, supplementing those in the jaw proper; in some extinct species the teeth on the vomers were actually larger than the primary set. In amphibians and reptiles, the vomers become narrower, due to the presence of the enlarged choanae (the inner part of the nostrils) on either side, and they may extend further back in the jaw. They are typically small in birds, where they form the upper hind part of the beak, again being located between the choanae. In mammals, the vomers have become narrower still, and are fused into a single, vertically oriented bone. The development of the hard palate beneath the vomer means that the bone is now located in a nasal chamber, separate from the mouth[WP]" xsd:string {source="http://en.wikipedia.org/wiki/Vomer#In_other_animals"} xref: UMLS:C0242403 [Term] id: UBERON:0012360 name: bone of jaw synonym: "jaw bone" EXACT [] comment: Editor notes: Do not manually classify under here - bones are automatically classified is_a: UBERON:0003462 ! facial bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0011595 ! jaw region relationship: part_of UBERON:0001708 ! jaw skeleton xref: SCTID:369003004 ! Entire bone of jaw [Term] id: UBERON:0004768 name: bone of lower jaw def: "Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular" [UBERON:cjm] comment: Editor notes: Do not manually classify under here - bones are automatically classified subset: grouping_class synonym: "lower jaw bone" EXACT [] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: part_of UBERON:0003278 ! skeleton of lower jaw relationship: develops_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest [Term] id: UBERON:0011597 ! bone of upper jaw name: bone of upper jaw def: "Any bone that is part of the upper jaw skeleton. This includes (when present): the maxilla, the quadrate (in some species)." [UBERON:cjm] comment: Editor notes: Do not manually classify under here - bones are automatically classified subset: grouping_class synonym: "upper jaw bone" EXACT [] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0003277 ! skeleton of upper jaw [Term] id: UBERON:0002398 name: manus def: "distal segment of the fore limb, including carpal region, metacarpal region and digits." [Wikipedia:Hand, Wikipedia:Manus_(anatomy)] comment: Usage notes: like all limb segments, this class encompasses both the unformed hand region of the embryo to the fully formed structure complete with skeleton subset: uberon_slim synonym: "hand" EXACT [MA:0000037] synonym: "forefoot of quadruped" NARROW [] synonym: "forefoot" NARROW INCONSISTENT [] synonym: "fore foot" NARROW INCONSISTENT [] synonym: "terminal segment of free upper limb" EXACT [] synonym: "fore-paw" NARROW SENSU [EMAPA:17428] synonym: "fore paw" NARROW SENSU [EMAPA:17428, OBOL:automatic] synonym: "forelimb autopod" EXACT [OBOL:automatic] synonym: "forelimb autopodium" EXACT [OBOL:automatic] synonym: "hand region" EXACT [EHDAA2:0000728] xref: FMA:9712 ! Hand xref: GAID:56 ! hand xref: galen:Hand xref: MA:0000037 ! hand xref: OpenCyc:Mx4rvViGVZwpEbGdrcN5Y29ycA xref: EMAPA:17428 ! fore-paw xref: EHDAA2:0000728 ! hand region xref: ncithesaurus:Hand ! Hand xref: OpenCyc:Mx4rvViGVZwpEbGdrcN5Y29ycA ! hand xref: NIF_GrossAnatomy:nlx_anat_20090603 ! Hand xref: VHOG:0000344 ! forelimb autopodium xref: BTO:0004668 ! hand xref: MESH:A01.378.800.667 ! hand xref: AAO:0010803 ! manus xref: SCTID:302539009 ! Entire hand intersection_of: UBERON:0002470 ! autopod region intersection_of: part_of UBERON:0002102 ! forelimb relationship: develops_from UBERON:0006875 ! handplate xref: http://upload.wikimedia.org/wikipedia/commons/7/76/LeftHand0.jpg property_value: has_relational_adjective "manual" xsd:string xref: UMLS:C0018563 [Term] id: UBERON:0002399 name: lesser omentum def: "The double layer of peritoneum that extends from the liver to the lesser curvature of the stomach and the start of the duodenum. [WP,unvetted]." [Wikipedia:Lesser_omentum] comment: editor note: exact part of and develops from relationships need to be established subset: uberon_slim synonym: "gastrohepatic omentum" RELATED [Wikipedia:Lesser_omentum] synonym: "small omentum" RELATED [Wikipedia:Lesser_omentum] xref: EHDAA:4858 ! lesser omentum xref: FMA:9715 ! Lesser omentum xref: VHOG:0000357 ! lesser omentum xref: MA:0001623 ! lesser omentum xref: ncithesaurus:Lesser_Omentum ! Lesser Omentum xref: EHDAA2:0000991 ! lesser omentum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Gray984.png/200px-Gray984.png xref: EMAPA:17890 ! lesser omentum of ventral mesogastrium of mesentery of stomach of foregut xref: EMAPA:18909 ! lesser omentum of ventral mesogastrium of mesentery of stomach of gut xref: EV:0100086 ! lesser omentum is_a: UBERON:0003688 ! omentum relationship: part_of UBERON:0001178 {source="FMA"} ! visceral peritoneum relationship: part_of UBERON:0005626 {source="MA"} ! ventral mesogastrium relationship: develops_from UBERON:0005626 {source="Wikipedia", source="EHDAA2"} ! ventral mesogastrium xref: SCTID:362712005 ! Entire lesser omentum synonym: "omentum minus" RELATED LATIN [Wikipedia:Lesser_omentum] xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Gray984.png property_value: external_definition "A membranous extension of the peritoneum from the peritoneal layers covering the ventral and the dorsal surfaces of the stomach and the first part of the duodenum. The lesser omentum extends from the portal fissure of the liver to the diaphragm, where the layers separate to enclose the end of the esophagus. It also forms two ligaments, one associated with the liver, the hepatogastric ligament, and the other, the heptatoduodenal ligament, with the duodenum. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000357", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/lesser+omentum", source="http://bgee.unil.ch/"} xref: UMLS:C0230260 [Term] id: UBERON:0002400 name: parietal pleura def: "Parietal serous membrane which is continuous with the visceral pleura and is attached to the dome of the diaphragm.[FMA]" [Wikipedia:Parietal_pleura, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:9733 ! Parietal pleura xref: VHOG:0001495 ! parietal pleura xref: MA:0002488 ! parietal pleura xref: ncithesaurus:Parietal_Pleura ! Parietal Pleura xref: OpenCyc:Mx4rvv2Uq5wpEbGdrcN5Y29ycA ! parietal pleura xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray968.png/200px-Gray968.png is_a: UBERON:0000042 ! serous membrane relationship: part_of UBERON:0000977 ! mesothoracic pleurum xref: SCTID:361998003 ! Entire parietal pleura synonym: "pleura parietalis" RELATED LATIN [Wikipedia:Parietal_pleura] xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray968.png xref: UMLS:C0225777 [Term] id: UBERON:0000977 name: pleura def: "The delicate serous membrane that lines each half of the thorax of mammals and is folded back over the surface of the lung of the same side[BTO]." [Wikipedia:Pleura] comment: In mouse, is_a cavity lining. In FMA, is_a (viscous) serous membrane (which includes mesothelium plus connective tissue). Note the MA structure should probably be associated with the mesothelium of pleura in FMA. JB/EHDAA2 argues the term 'pleura' is best used for the mesothelial lining (thus excluding connective tissue). See http://purl.obolibrary.org/obo/uberon/tracker/86 subset: uberon_slim synonym: "pleura" RELATED [] synonym: "wall of pleural sac" EXACT [] synonym: "pleural tissue" RELATED [BTO:0001791] xref: FMA:9583 ! Pleura xref: GAID:360 ! pleura xref: VHOG:0000394 ! pleura xref: MA:0000433 ! pleura xref: OpenCyc:Mx4rv3zwLZwpEbGdrcN5Y29ycA xref: ncithesaurus:Pleural_Tissue ! Pleura xref: BTO:0001791 ! pleura xref: EFO:0001980 ! pleura xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Gray965.png/200px-Gray965.png xref: MESH:A04.716 ! pleura xref: EV:0100044 ! pleura intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0009778 ! pleural sac is_a: UBERON:0000042 {source="MESH"} ! serous membrane relationship: part_of UBERON:0009778 {source="FMA"} ! pleural sac relationship: part_of UBERON:0001004 ! respiratory system relationship: surrounds UBERON:0002402 ! pleural cavity relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: SCTID:181609007 ! Entire pleura property_value: external_definition "The serous membrane that covers the lungs and lines the pleural cavity. [Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.264][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000394", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: has_relational_adjective "pleural" xsd:string xref: UMLS:C0032225 [Term] id: UBERON:0009778 name: pleural sac def: "Serous sac, which has as parts the pleura and the pleural cavity. Examples: There are only two canonical instances, right and left pleural sacs." [FMA:9690] is_a: UBERON:0005906 {source="FMA"} ! serous sac relationship: part_of UBERON:0001558 {source="FMA"} ! lower respiratory tract xref: FMA:9690 ! pleural sac xref: SCTID:361996004 ! Entire pleural sac relationship: in_lateral_side_of UBERON:0001004 {source="FMA-abduced-lr"} ! respiratory system [Term] id: UBERON:0002401 name: visceral pleura def: "Visceral serous membrane which is continuous with the parietal pleura and is attached to the parenchyma of lobe of lung.[FMA]" [Wikipedia:Visceral_pleura, FMA:FMA] comment: See comments for pleura subset: uberon_slim synonym: "pleura visceralis (pulmonalis)" EXACT [] synonym: "pulmonary pleura" EXACT [] synonym: "lung pleura" RELATED [] synonym: "lung mesothelium" RELATED [EHDAA2:0002205] synonym: "pleura pulmonalis" EXACT LATIN [FMA:TA, FMA:9734] synonym: "pleura visceralis" EXACT LATIN [Wikipedia:Visceral_pleura] xref: FMA:9734 ! Visceral pleura xref: MA:0002489 ! visceral pleura xref: ncithesaurus:Visceral_Pleura ! Visceral Pleura xref: OpenCyc:Mx4rwNFqppwpEbGdrcN5Y29ycA ! visceral pleura xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Gray968.png/200px-Gray968.png is_a: UBERON:0000042 ! serous membrane relationship: part_of UBERON:0000977 ! mesothoracic pleurum relationship: attaches_to UBERON:0008946 ! lung parenchyma relationship: part_of UBERON:0002048 {source="FMA"} ! lung relationship: part_of UBERON:0000977 {source="FMA"} ! pleura xref: SCTID:361997008 ! Entire visceral pleura xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray968.png xref: VHOG:0001496 ! visceral pleura xref: EHDAA2:0002205 ! lung mesothelium property_value: external_definition "Each lung is invested by an exceedingly delicate serous membrane, the pleura, which is arranged in the form of a closed invaginated sac. A portion of the serous membrane covers the surface of the lung and dips into the fissures between its lobes; it is called the pulmonary pleura (or visceral pleura). The visceral pleura is attached directly to the lungs[Wikipedia:Visceral_pleura]." xsd:string {source="Wikipedia:Visceral_pleura"} xref: UMLS:C0225776 [Term] id: UBERON:0002402 name: pleural cavity def: "Cavity of serous sac surropunded by the pleura.[FMA]" [Wikipedia:Pleural_cavity, FMA:FMA] comment: Note the EHDAA2 class is not quite equivalent. See http://purl.obolibrary.org/obo/uberon/tracker/86 subset: uberon_slim xref: FMA:9740 ! Pleural cavity xref: GAID:95 ! pleural cavity xref: VHOG:0000581 ! pleural cavity xref: MA:0000055 ! pleural cavity xref: ncithesaurus:Pleural_Cavity ! Pleural Cavity xref: OpenCyc:Mx4rwCKAppwpEbGdrcN5Y29ycA ! pleural cavity xref: EHDAA2:0001475 ! pleural cavity xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Gray965.png/200px-Gray965.png xref: BTO:0004422 ! pleural cavity xref: EMAPA:18462 ! pleural cavity xref: MESH:A01.911.800.650 ! pleural cavity intersection_of: UBERON:0002323 ! coelemic cavity lumen intersection_of: part_of UBERON:0009778 ! pleural sac relationship: part_of UBERON:0009778 {source="FMA"} ! pleural sac relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom xref: SCTID:361999006 ! Entire pleural cavity synonym: "cavitas pleurallis" RELATED LATIN [Wikipedia:Pleural_cavity] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png property_value: homology_notes "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {external_class="VHOG:0000581", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0178802 [Term] id: UBERON:0002403 name: internal intercostal muscle def: "Intercostal muscles are several groups of muscles that run between the ribs, and help form and move the chest wall. There are three principal layers; the external intercostal muscles, which aid in quiet and forced inhalation. They originate on ribs 1-11 and have their insertion on ribs 2-12. The external intercostals are responsible for the elevation of the ribs, and expanding the transverse dimensions of the thoracic cavity. Located around the ribs the internal intercostal muscles, which aid in forced expiration (quiet expiration is a passive process). They originate on ribs 2-12 and have their insertions on ribs 1-11. The internal intercostals are responsible for the depression of the ribs decreasing the transverse dimensions of the thoracic cavity. the innermost intercostal muscle, the deep layers of the internal intercostal muscles which are separated from them by the neurovascular bundle. Both the external and internal muscles are innervated by the intercostal nerves, and are provided by the intercostal arteries and intercostal veins. Their fibers run in opposite directions. [WP,unvetted]." [Wikipedia:Intercostal_muscle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "intercostal muscle internal layer" RELATED [] synonym: "intercostales internus" EXACT [] xref: FMA:9757 ! Internal intercostal muscle xref: VHOG:0000905 ! intercostales internus xref: MA:0002326 ! intercostales internus xref: ncithesaurus:Internal_Intercostal_Muscle ! Internal Intercostal Muscle xref: OpenCyc:Mx4rvlj6HZwpEbGdrcN5Y29ycA ! internal intercostal muscle xref: EHDAA2:0000875 ! internal intercostal muscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Gray411.png/200px-Gray411.png is_a: UBERON:0001111 ! intercostal muscle relationship: develops_from UBERON:0010981 {source="EHDAA2"} ! internal intercostal pre-muscle mass xref: SCTID:244890001 ! Entire internal intercostal muscle property_value: homology_notes "Behind the thorax, the lateral group (of muscles in reptiles and mammals) remains essentially as for amphibians. (It breaks into three sheet-like layers: external oblique muscle, the internal oblique, and the transversus). More anteriorly, however, the ribs, now enlarged, penetrate and alter this group of muscles. The transversus is excluded from the thorax and the external and internal obliques become, respectively, the external and internal intercostal muscles, which contribute to the new function of ventilation of the lungs.[well established][VHOG]" xsd:string {external_class="VHOG:0000905", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.193", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1744536 [Term] id: UBERON:0010981 name: internal intercostal pre-muscle mass is_a: UBERON:0010970 {source="EHDAA2"} ! intercostal pre-muscle mass relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group xref: EHDAA2:0000876 ! internal intercostal pre-muscle mass [Term] id: UBERON:0002404 name: transversus thoracis def: "The tranversus thoracis lies internal to the thoracic cage, anteriorly. It is a thin plane of muscular and tendinous fibers, situated upon the inner surface of the front wall of the chest. It is in the same layer as the subcostal muscles. It arises on either side from the lower third of the posterior surface of the body of the sternum, from the posterior surface of the xiphoid process, and from the sternal ends of the costal cartilages of the lower three or four true ribs. Its fibers diverge upward and lateralward, to be inserted by slips into the lower borders and inner surfaces of the costal cartilages of the second, third, fourth, fifth, and sixth ribs. The lowest fibers of this muscle are horizontal in their direction, and are continuous with those of the Transversus abdominis; the intermediate fibers are oblique, while the highest are almost vertical. This muscle varies in its attachments, not only in different subjects, but on opposite sides of the same subject. [WP,unvetted]." [Wikipedia:Transversus_thoracis] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: FMA:9760 ! Transversus thoracis xref: MA:0002397 ! transversus thoracis xref: ncithesaurus:Transversus_Thoracis ! Transversus Thoracis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ef/Transversus_thoracis.png/200px-Transversus_thoracis.png xref: EMAPA:19267 ! transversus thoracis is_a: UBERON:0002426 ! chest muscle xref: SCTID:244933000 ! Entire transversus thoracis subset: organ_slim xref: UMLS:C1744608 [Term] id: UBERON:0002405 name: immune system def: "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [NLM:immune+system, Wikipedia:Immune_system] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core xref: BILA:0000104 xref: FMA:9825 ! Immune system xref: GAID:328 ! immune system xref: VHOG:0001247 ! immune system xref: MA:0002711 ! immune system xref: OpenCyc:Mx4rvWNkm5wpEbGdrcN5Y29ycA xref: TAO:0001159 ! immune system xref: XAO:0003152 ! immune system xref: ZFA:0001159 ! immune system xref: ncithesaurus:Immune_System ! Immune System xref: OpenCyc:Mx4rvWNkm5wpEbGdrcN5Y29ycA ! immune system xref: MESH:A15.382 ! immune system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0000949 ! endocrine system disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001008 ! urinary system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system xref: AAO:0011003 ! immune system xref: SCTID:362590003 ! Entire immune system property_value: homology_notes "The antibody-based immune system defined by the presence of the major histocompatibility complex (MHC), T cell receptor (TCR), B cell receptor (BCR) or recombination activating genes (RAGs) is known beginning from jawed fishes.[well established][VHOG]" xsd:string {external_class="VHOG:0001247", ontology="VHOG", source="PMID:21046016 Dzik JM\, The ancestry and cumulative evolution of immune reactions. Acta biochimica Polonica (2010)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0020962 [Term] id: UBERON:0002406 name: pericardial sac def: "Serous sac, which has as parts the serous pericardium and the pericardial cavity [FMA]." [FMA:9868] comment: We follow FMA in dividing pericardial sac in pericardium and pericardial cavity subset: uberon_slim subset: vertebrate_core synonym: "pericardium" RELATED [] xref: FMA:9868 ! Pericardial sac xref: TAO:0000054 ! pericardial sac (also: UBERON:0002407 'pericardium') xref: RETIRED_EHDAA2:0001443 ! pericardium (also: UBERON:0002407 'pericardium') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Gray489.png/200px-Gray489.png intersection_of: UBERON:0005906 ! serous sac intersection_of: has_part UBERON:0001074 ! pericardial cavity intersection_of: has_part UBERON:0002357 ! serous pericardium relationship: part_of UBERON:0001009 ! circulatory system relationship: part_of UBERON:0002407 ! pericardium relationship: surrounded_by UBERON:0002359 {source="FMA"} ! fibrous pericardium xref: SCTID:361326002 ! Entire pericardial sac [Term] id: UBERON:0002407 name: pericardium def: "The outer membrane/wall of the developing heart, surrounding the myocardium. " [Wikipedia:Pericardium] comment: We follow FMA in dividing pericardial sac in pericardium and pericardial cavity subset: uberon_slim subset: vertebrate_core xref: BTO:0000717 xref: EFO:0000820 ! pericardium xref: EHDAA:5376 ! pericardium xref: FMA:9869 ! Pericardium xref: GAID:569 ! pericardium xref: VHOG:0001280 ! pericardium xref: MA:0000099 ! pericardium xref: MAT:0000454 ! pericardium xref: ZFA:0000054 ! pericardium xref: ncithesaurus:Pericardium ! Pericardium xref: galen:Pericardium ! pericardium xref: OpenCyc:Mx4rvoCLgJwpEbGdrcN5Y29ycA ! pericardium xref: RETIRED_EHDAA2:0001443 ! pericardium (also: UBERON:0002406 'pericardial sac') xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Gray489.png/200px-Gray489.png xref: EMAPA:17174 ! pericardium xref: MESH:A07.541.795 ! pericardium xref: EV:0100023 ! pericardium is_a: UBERON:0000483 {source="GO"} ! epithelium is_a: UBERON:0004457 ! cavity lining relationship: has_part UBERON:0002359 ! fibrous pericardium relationship: has_part UBERON:0002406 ! pericardial sac relationship: part_of UBERON:0000948 {source="XAO"} ! heart relationship: surrounds UBERON:0002349 ! myocardium xref: AAO:0010817 ! pericardium xref: SCTID:181295003 ! Entire pericardium xref: XAO:0004182 ! pericardium xref: TAO:0000054 ! pericardial sac (also: UBERON:0002406 'pericardial sac') xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png property_value: external_definition "Peritoneum that surrounds the heart.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010817", date_retrieved="2012-06-20", source="AAO:JMG"} property_value: has_relational_adjective "pericardial" xsd:string xref: UMLS:C0031050 [Term] id: UBERON:0002408 name: parietal serous pericardium def: "Parietal serous membrane which is continuous with the visceral serous pericardium and is attached to the central tendon of diaphragm.[FMA]" [Wikipedia:Parietal_pericardium, FMA:FMA] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lamina parietalis (pericardii serosum)" EXACT [] synonym: "parietal layer of serous pericardium" EXACT [] synonym: "parietal pericardium" EXACT [] xref: EHDAA:3422 ! parietal pericardium xref: EHDAA:5378 ! parietal pericardium xref: FMA:9870 ! Parietal serous pericardium xref: VHOG:0000537 ! parietal pericardium xref: MA:0000483 ! parietal serous pericardium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Gray489.png/200px-Gray489.png xref: EMAPA:17175 ! parietal pericardium xref: EMAPA:19031 ! parietal of serosal pericardium is_a: UBERON:0000042 ! serous membrane relationship: part_of UBERON:0002357 ! serous pericardium synonym: "lamina parietalis pericardii" EXACT LATIN [FMA:TA, FMA:9870] xref: SCTID:243956000 ! Entire parietal pericardium xref: ncithesaurus:Parietal_Pericardium ! parietal pericardium xref: UMLS:C0225969 [Term] id: UBERON:0002409 name: pericardial fluid def: "Transudate contained in the pericardial cavity.[FMA]" [Wikipedia:Pericardial_fluid, FMA:9887] subset: uberon_slim xref: BTO:0001016 xref: FMA:9887 ! Pericardial fluid xref: MA:0002530 ! pericardial fluid is_a: UBERON:0007794 {source="FMA"} ! serous fluid intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0002425 ! visceral serous pericardium [Term] id: UBERON:0002410 name: autonomic nervous system def: "The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]." [Wikipedia:Autonomic_nervous_system] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "ANS" RELATED [] synonym: "visceral nervous system" EXACT [] xref: AAO:0000033 ! autonomic_nervous_system xref: EHDA:10095 ! autonomic xref: FMA:9905 ! Autonomic nervous system xref: GAID:706 ! autonomic nervous system xref: VHOG:0000396 ! autonomic nervous system xref: MA:0000219 ! autonomic nervous system xref: NIF_GrossAnatomy:birnlex_1123 ! Autonomic nervous system xref: TAO:0001574 ! autonomic nervous system xref: ZFA:0001574 ! autonomic nervous system xref: ncithesaurus:Autonomic_Nervous_System ! Autonomic Nervous System xref: BTO:0002507 ! autonomic nervous system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f7/Gray839.png/200px-Gray839.png xref: EMAPA:16984 ! autonomic (also: UBERON:0005433 'autonomic peripheral nervous system') xref: MESH:A08.800.050 ! autonomic nervous system (also: UBERON:0005433 'autonomic peripheral nervous system') xref: EHDAA:3767 ! autonomic (also: UBERON:0005433 'autonomic peripheral nervous system') is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0000010 ! peripheral nervous system xref: SCTID:362481007 ! Entire autonomic nervous system synonym: "divisio autonomica systematis nervosi peripherici" RELATED LATIN [Wikipedia:Autonomic_nervous_system] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png property_value: external_definition "Part of the peripheral nervous system which regulates involuntary functions of the body and consists of the sympathetic and parasympathetic system.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000033", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Nervous system including a portion of the central and peripheral systems and presiding over the control and coordination of the vegetative functions of the organism. It innervates smooth and cardiac muscles and glandular tissues and is responsible for many actions which are more or less automatic (e.g. secretion, vasoconstriction etc.). It consists of the sympathetic and parasympathetic nervous systems. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000396", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "From comparative analyses of craniate brains, a morphotype of the brain in the earliest craniate stock can be constructed. In marked contrast to cephalochordates, the ancestral craniate morphotype had a plethora of unique features, which included a telencephalon with pallial and subpallial parts, paired olfactory bulbs with substantial projections to most or all of the telencephalic pallium, paired lateral eyes and ears, a lateral line system for both electroreception and mechanoreception, spinal cord dorsal root ganglia, and an autonomic nervous system.[well established][VHOG]" xsd:string {external_class="VHOG:0000396", ontology="VHOG", source="DOI:10.1002/1097-0185(20000615)261:3<111::AID-AR6>3.0.CO;2-F Butler AB\, Chordate evolution and the origin of craniates: An old brain in a new head. AnaT Rec (New Anat) (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0004388 [Term] id: UBERON:0002411 name: clitoris def: "The clitoris is a sexual organ that is present only in female mammals. In humans, the visible button-like portion is located near the anterior junction of the labia minora, above the opening of the urethra and vagina. Unlike the penis, which is homologous to the clitoris, the clitoris does not contain the distal portion of the urethra. The only known exception to this is in the Spotted Hyena. In this species, the urogenital system is unique in that the female urinates, mates and gives birth via an enlarged, erectile clitoris, known as a pseudo-penis. In humans, the clitoris is the most sensitive erogenous zone of a woman, the stimulation of which may produce sexual excitement and clitoral erection; its continuing stimulation may produce sexual pleasure in the woman and orgasm. [WP,unvetted]." [Wikipedia:Clitoris] subset: uberon_slim xref: FMA:9909 ! Clitoris xref: GAID:385 ! clitoris xref: galen:Clitoris xref: VHOG:0000700 ! clitoris xref: MA:0000382 ! clitoris xref: ncithesaurus:Clitoris xref: OpenCyc:Mx4rvVjr6ZwpEbGdrcN5Y29ycA xref: BTO:0002020 ! clitoris xref: EHDAA:9360 ! clitoris xref: OpenCyc:Mx4rvVjr6ZwpEbGdrcN5Y29ycA ! clitoris xref: EHDAA2:0000255 ! clitoris xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Clitoris_anatomy_labeled-en.svg/200px-Clitoris_anatomy_labeled-en.svg.png xref: EMAPA:30819 ! clitoris xref: MESH:A05.360.319.887.436 ! clitoris is_a: UBERON:0000062 {source="Wikipedia"} ! organ relationship: part_of UBERON:0000997 {source="MA"} ! vulva relationship: develops_from UBERON:0005876 {source="Wikipedia", source="EHDAA2"} ! genital tubercle relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia xref: SCTID:181442003 ! Entire clitoris subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Clitoris_anatomy_labeled-en.svg property_value: has_relational_adjective "clitoral" xsd:string xref: UMLS:C0008984 [Term] id: UBERON:0002415 name: tail def: "section at the rear end of an animal's body; in general, the term refers to a distinct, flexible appendage to the torso[WP]." [ISBN:0471209627, OMD:tail, Wikipedia:Tail, ZFIN:curator] comment: Editor notes: Note we also have a subclass post-anal tail, for the chordate specific structure. currently defined very generally, inclusive of caudal fin subset: uberon_slim subset: grouping_class synonym: "caudal subdivision" EXACT [UBERON:cjm] xref: BTO:0001348 xref: EHDAA:9198 ! tail xref: GAID:1245 ! tail xref: MAT:0000094 ! tail xref: MIAA:0000094 ! tail xref: OpenCyc:Mx4rvVjiC5wpEbGdrcN5Y29ycA xref: WBbt:0005741 ! tail xref: EFO:0000963 ! tail xref: AEO:0000109 ! tail xref: MESH:A13.895 ! tail xref: BILA:0000117 ! tail is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000154 ! posterior region of body [Term] id: UBERON:0007812 ! post-anal tail name: post-anal tail def: "a tail that extends from the posterior tip of the organism to the anus, contains muscle and skeleton." [UBERON:cjm] comment: Taxon notes: present at some time in chordate life history (eg in Urochordates, present only in free-swimming larvae). Function: propellor locomotion (in some species) synonym: "post-anal fin tail" NARROW SENSU [http://purl.oboibrary.org/obo/uberon/tracker/185] synonym: "postanal tail" EXACT [] synonym: "muscular postanal tail" EXACT [] synonym: "post-vent region" RELATED [TAO:0001117] subset: vertebrate_core xref: MA:0000008 ! tail xref: ZFA:0001117 ! post-vent region xref: EHDAA2:0003109 ! tail xref: XAO:0003026 ! tail xref: ncithesaurus:Tail ! Tail xref: AAO:0010338 ! tail is_a: UBERON:0002415 ! tail relationship: develops_from UBERON:0002533 ! tail bud relationship: only_in_taxon NCBITaxon:7711 {source="cjm"} ! Chordata relationship: has_function_in GO:0007626 ! locomotory behavior xref: TAO:0001117 ! post-vent region property_value: external_definition "Anatomical structure that is the terminal, flexible posterior appendage of the organism.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010338", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Organism subdivision which is the part of the body posterior to the vent which includes the anal and caudal fins.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001117", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0039259 [Term] id: UBERON:0007844 ! cartilage element name: cartilage element def: "Skeletal element that is composed of cartilage tissue and may be permanent or transient." [VSAO:curator] comment: AO notes: TAO still mixes tissue and element synonym: "chondrogenic element" EXACT [VSAO:0000000] synonym: "cartilage organ" EXACT [FMA:55107] synonym: "cartilage" RELATED [VSAO:0000000] synonym: "cartilaginous element" EXACT [UBERON:cjm] xref: VSAO:0000000 ! cartilage element xref: FMA:55107 ! cartilage organ xref: ZFA:0001501 ! cartilage element xref: XAO:0004013 ! cartilage element xref: AAO:0011130 ! cartilage element is_a: UBERON:0004765 {source="VSAO"} ! skeletal element relationship: has_part UBERON:0002418 {source="VSAO"} ! cartilage relationship: develops_from UBERON:0005863 {source="VSAO"} ! cartilaginous condensation subset: organ_slim [Term] id: UBERON:0002418 name: cartilage tissue def: "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts[VSAO]." [VSAO:0000040, Wikipedia:Cartilage, http://sourceforge.net/tracker/?func=detail&atid=2257941&aid=3396584&group_id=76834] comment: Previous: "A portion of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate[GO]. Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage[FMA]. an avascular supporting and articular skeletal tissue. It also functions as the primary endoskeletal support in vertebrate embryos. Cartilage is deposited by and is composed of chondroblasts and chondrocytes separated by an extracellular matrix, which may or may not mineralize depending on cartilage type, age, or taxon[Hall and Witten]." See also FMA:71500 Set of cartilages, FMA:55107 Cartilage organ, FMA:12264 Articular cartilage. // elements made from cartilage, cartilage-like, or chondroid tissues evolved in invertebrates[H&W] subset: uberon_slim subset: vertebrate_core synonym: "cartilage" RELATED [] synonym: "cartilage tissue" EXACT [FMA:37377] synonym: "cartilaginous tissue" EXACT [] xref: AAO:0000060 ! cartilage xref: BTO:0000206 xref: GAID:99 ! cartilage xref: galen:Cartilage xref: VHOG:0001207 ! cartilage xref: MA:0000104 ! cartilage tissue xref: MAT:0000189 ! cartilage xref: MIAA:0000189 ! cartilage xref: OpenCyc:Mx4rvVjeOZwpEbGdrcN5Y29ycA xref: TAO:0001501 ! cartilage xref: XAO:0000170 ! cartilage tissue xref: FMA:37377 ! Cartilage tissue xref: EFO:0000949 ! cartilage xref: OpenCyc:Mx4rvVjeOZwpEbGdrcN5Y29ycA ! cartilage xref: EHDAA2:0003087 ! cartilage xref: AEO:0000087 ! cartilage xref: MESH:A02.165 ! cartilage xref: EV:0100141 ! cartilage xref: VSAO:0000040 ! cartilage tissue xref: ZFA:0005622 ! cartilage tissu xref: ncithesaurus:Cartilagenous_Tissue ! cartilaginous tissue xref: ncithesaurus:Cartilage is_a: UBERON:0002384 ! connective tissue is_a: UBERON:0004755 ! skeletal tissue relationship: part_of UBERON:0002204 ! musculoskeletal system relationship: has_part CL:0000138 ! chondrocyte xref: SCTID:309312004 ! Cartilage tissue xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg property_value: external_definition "A type of dense connective tissue. It is composed of cells called chondrocytes which are dispersed in a firm gel-like ground substance, called the matrix. Cartilage is avascular (contains no blood vessels) and nutrients are diffused through the matrix. Cartilage is found in the joints, the rib cage, the ear, the nose, in the throat and between intervertebral disks. It makes up virtually the entire skeleton in chondrichthyes.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000060", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000060", date_retrieved="2012-06-20"} property_value: external_definition "Portion of tissue which is connective tissue composed of collagen and/or elastin fibers and chondrocytes. Cartilage is avascular and provides both skeletal functions and a framework upon which bone is deposited.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001501", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000040", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170"} synonym: "cartilages" RELATED [VHOG:0001207] synonym: "chondrogenic tissue" EXACT [VSAO:0000040] property_value: homology_notes "Phylogenetic analysis suggests that cartilage arose independently in cnidarians, hemichordates, vertebrates, arthropods, annelids, brachiopods, and molluscs - or a common ancestor of brachiopods and molluscs (...). Analyses of cartilage as a tissue and of the development of invertebrate cartilages are consistent with homology between invertebrate and vertebrate cartilage. From the discussion above, it will be clear that understanding genetic changes underlying cartilage evolution is key to determining whether the multiple origins of cartilage represent parallel evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0001207", ontology="VHOG", source="DOI:10.1111/j.1525-142X.2011.00520.x Hall BK\, Parallelism\, deep homology\, and evo-devo. Evolution and Development (2012)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0007301 [Term] id: UBERON:0010364 name: dermal skeleton def: "Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements." [VSAO:0000035] comment: This ontology covers metazoa, so we do not use exoskeleton as primary label, as in VSAO synonym: "dermal skeletal system" RELATED [VSAO:curator] synonym: "dermoskeleton" RELATED [VSAO:curator] synonym: "desmoskeleton" RELATED [VSAO:curator] synonym: "exoskeleton" BROAD INCONSISTENT [VSAO:curator] is_a: UBERON:0010912 {source="VSAO"} ! subdivision of skeleton xref: VSAO:0000035 ! dermal skeleton xref: XAO:0004025 ! dermal skeleton [Term] id: UBERON:0010365 name: odontoid tissue def: "Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla." [VSAO:0000063] synonym: "tooth tissue" RELATED [] synonym: "dental tissue" RELATED [VSAO:curator] synonym: "odontogenic tissue" EXACT [VSAO:curator] intersection_of: UBERON:0004755 ! skeletal tissue intersection_of: part_of UBERON:0010364 ! dermal skeleton intersection_of: develops_from UBERON:0001763 ! odontogenic papilla xref: VSAO:0000063 ! odontoid tissue xref: XAO:0004046 ! odontoid tissue xref: ZFA:0005623 ! odontoid tissue xref: ncithesaurus:Tooth_Tissue ! Odontogenic Tissue xref: UMLS:C1519551 [Term] id: UBERON:0002419 name: skin gland def: "A gland that is part of a skin of body [Automatically generated definition]." [OBOL:automatic] comment: check FMA, use plural for now as general class not there synonym: "skin glands" RELATED PLURAL [] synonym: "skin glands set" RELATED PLURAL [] xref: FMA:71878 ! Set of skin glands xref: MA:0000146 ! skin gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002097 ! skin of body synonym: "glandulae cutis" EXACT LATIN [FMA:TA, FMA:71878] subset: organ_slim synonym: "set of skin glands" RELATED [FMA:71878] [Term] id: UBERON:0010009 name: aggregate regional part of brain def: "A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]." [NIF_GrossAnatomy:nlx_anat_20090509] synonym: "set of nuclei of neuraxis" EXACT [FMA:256381] is_a: UBERON:0002616 {source="NIF"} ! regional part of brain xref: NIF_GrossAnatomy:nlx_anat_20090509 ! Aggregate regional part of brain xref: FMA:256381 ! set of nuclei of neuraxis [Term] id: UBERON:0010011 ! collection of basal ganglia name: collection of basal ganglia comment: Editor note: it is necessary to introduce two classes, one representing an individual basal ganglion, another representing the aggregate structure, in order to have consistent classification amongst AOs (e.g. in MA the aygdala is part of the BG, in FMA and BTO it is a subclass). Apart from achieving this consistency, the value of having two distinct classes is questionable, since the BG-plural is trivially the collection of all BGs-singular. it would be better for all AOs to decide on one single way of doing this. Do not merge until this is done. synonym: "basal ganglia" EXACT [FMA:84013] synonym: "basal ganglia set" EXACT [FMA:84013] synonym: "set of basal ganglia" EXACT [FMA:84013] is_a: UBERON:0010009 {source="FMA"} ! aggregate regional part of brain relationship: part_of UBERON:0000454 {source="FMA"} ! cerebral subcortex relationship: part_of UBERON:0001893 {source="NIF"} ! telencephalon xref: GAID:617 ! basal ganglia xref: FMA:84013 ! set of basal ganglia xref: MESH:A08.186.211.730.885.105 ! basal ganglia xref: BM:Tel-BG ! basal ganglia xref: MA:0000184 ! basal ganglia xref: NIF_GrossAnatomy:birnlex_826 ! Basal ganglia xref: ncithesaurus:Basal_Ganglia ! Basal Ganglia xref: VHOG:0001696 ! basal ganglia property_value: homology_notes "All nuclei of the mammalian basal ganglia are also present in the oldest vertebrates.[well established][VHOG]" xsd:string {external_class="VHOG:0001696", ontology="VHOG", source="DOI:10.1016/j.cub.2011.05.001 Stephenson-Jones M\, Samuelsson E\, Ericsson J\, Robertson B\, Grillner S\, Evolutionary conservation of the basal ganglia as a common vertebrate mechanism for action selection. Current Biology (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0004781 [Term] id: UBERON:0002420 name: basal ganglion def: "one of a group of nuclei in the brains of vertebrates, situated at the base of the forebrain and strongly connected with the cerebral cortex, thalamus and other areas.ganglion in the head. The main components of the basal ganglia are the striatum, pallidum, substantia nigra, and subthalamic nucleus[WP]. Subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF]." [Wikipedia:Basal_ganglia] comment: Editor note: it is necessary to introduce two classes, one representing an individual basal ganglion, another representing the aggregate structure, in order to have consistent classification amongst AOs (e.g. in MA the aygdala is part of the BG, in FMA and BTO it is a subclass). Apart from achieving this consistency, the value of having two distinct classes is questionable, since the BG-plural is trivially the set of all BGs-singular. it would be better for all AOs to decide on one single way of doing this. Do not merge until this is done. subset: uberon_slim synonym: "basal ganglia" RELATED PLURAL [] synonym: "basal ganglion of telencephalon" EXACT [] synonym: "basal nucleus" RELATED [MA:0000184] xref: FMA:62514 ! Basal ganglion of telencephalon xref: EFO:0000904 ! basal ganglion xref: BTO:0000235 ! basal ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/Basal_Ganglia_and_Related_Structures.svg/200px-Basal_Ganglia_and_Related_Structures.svg.png is_a: UBERON:0007245 {source="FMA"} ! nuclear complex of neuraxis relationship: part_of UBERON:0010011 ! collection of basal ganglia disjoint_from: UBERON:0000045 {inconsistent_with="BTO"} ! ganglion xref: SCTID:244434001 ! Entire basal ganglion synonym: "nuclei basales" RELATED LATIN [Wikipedia:Basal_ganglia] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/Basal_Ganglia_and_Related_Structures.svg [Term] id: UBERON:0010010 name: basal nucleus of telencephalon def: "Subdivision of telencephalon which is actually several islands of neurons lying within the substantia innominata, located ventral to the basal ganglia and anterior to the hypothalamus." [FMA:61887, Wikipedia:Nucleus_basalis_of_Meynert] comment: AO notes: MA has basal nucleus as synonym for BG. Function notes: rich in acetylcholine and choline acetyltransferase[WP]. Location notes: The NBM is inferior to the globus pallidus and within an area known as the substantia innominata synonym: "nucleus basalis" EXACT [NIF_GrossAnatomy:birnlex_1107] synonym: "nucleus basalis of Meynert" EXACT [NIF_GrossAnatomy:birnlex_1107] synonym: "basal nucleus" EXACT [NIF_GrossAnatomy:birnlex_1107] synonym: "basal magnocellular nucleus (substantia innominata)" EXACT [FMA:61887] synonym: "basal nuclei of Meynert" EXACT [FMA:61887] synonym: "basal nucleus of Meynert" EXACT [FMA:61887] synonym: "basal substance of telencephalon" EXACT [FMA:61887] synonym: "ganglion of Meynert" EXACT [FMA:61887] synonym: "Meynert's nucleus" EXACT [FMA:61887] synonym: "substantia basalis telencephali" EXACT LATIN [FMA:TA] is_a: UBERON:0002308 {source="FMA"} ! nucleus of brain relationship: part_of UBERON:0003017 {source="WP"} ! substantia innominata xref: NIF_GrossAnatomy:birnlex_1107 ! basal nucleus xref: FMA:61887 ! basal nucleus of telencephalon disjoint_from: UBERON:0002266 {source="NIF_GrossAnatomy"} ! anterior olfactory nucleus disjoint_from: UBERON:0001883 {source="NIF_GrossAnatomy"} ! anterior perforated substance disjoint_from: UBERON:0001881 {source="NIF_GrossAnatomy"} ! island of calleja disjoint_from: UBERON:0002599 {source="NIF_GrossAnatomy"} ! medial olfactory gyrus disjoint_from: UBERON:0002264 {source="NIF_GrossAnatomy"} ! olfactory bulb disjoint_from: UBERON:0001882 {source="NIF_GrossAnatomy"} ! nucleus accumbens disjoint_from: UBERON:0003017 {source="NIF_GrossAnatomy"} ! substantia innominata disjoint_from: UBERON:0003020 {source="NIF_GrossAnatomy"} ! subcallosal area synonym: "nucleus basalis telencephali" RELATED LATIN [Wikipedia:Nucleus_basalis_of_Meynert] xref: http://upload.wikimedia.org/wikipedia/commons/3/36/Substantia_innominata_MRI.PNG xref: SCTID:369109003 ! Entire nucleus basalis of Meynert [Term] id: UBERON:0002107 name: liver def: "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." [BTO:0000759, Wikipedia:Liver] comment: AO notes: Only ZFA considers this part_of immune system - we weaken this to an overlaps relation, as in general it's only a subset of cells that have clear immune function. Taxon notes: WP: The liver is found in all vertebrates, and is typically the largest visceral organ. Its form varies considerably in different species, and is largely determined by the shape and arrangement of the surrounding organs. Nonetheless, in most species it is divided into right and left lobes; exceptions to this general rule include snakes, where the shape of the body necessitates a simple cigar-like form. The internal structure of the liver is broadly similar in all vertebrates.[7] An organ sometimes referred to as a liver is found associated with the digestive tract of the primitive chordate Amphioxus. However, this is an enzyme secreting gland, not a metabolic organ, and it is unclear how truly homologous it is to the vertebrate liver. // The zebrafish liver differs from the mammalian liver in that the hepatocytes are not clearly organized in cords or lobules and the typical portal triads are not apparent. In addition, the zebrafish liver does not have Kuppfer cells. Furthermore, a clear distinction can be made between the male and female liver in the adult zebrafish. The female hepatocytes are very basophilic (Figure 15c) as a result of the production of vitellogenin (Van der Ven et al. 2003). subset: uberon_slim subset: vertebrate_core subset: major_organ xref: BTO:0000759 xref: EFO:0000887 ! liver xref: EHDAA:2197 ! liver xref: FMA:7197 ! Liver xref: GAID:288 ! liver xref: VHOG:0000257 ! liver xref: MA:0000358 ! liver xref: MAT:0000097 ! liver xref: MIAA:0000097 ! liver xref: ncithesaurus:Liver xref: OpenCyc:Mx4rvVimppwpEbGdrcN5Y29ycA xref: TAO:0000123 ! liver xref: XAO:0000133 ! liver xref: ZFA:0000123 ! liver xref: galen:Liver ! liver xref: OpenCyc:Mx4rvVimppwpEbGdrcN5Y29ycA ! liver xref: EHDAA2:0000997 ! liver xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Leber_Schaf.jpg/200px-Leber_Schaf.jpg xref: EMAPA:16846 ! liver xref: MESH:A03.620 ! liver xref: EV:0100089 ! liver is_a: UBERON:0002365 ! exocrine gland relationship: has_part CL:0000182 ! hepatocyte relationship: part_of UBERON:0000916 {source="FMA"} ! abdomen relationship: part_of UBERON:0000949 {source="EHDAA2"} ! endocrine system relationship: part_of UBERON:0002330 {source="EHDAA2"} ! exocrine system relationship: overlaps UBERON:0002405 {source="ZFA-weakened"} ! immune system relationship: part_of UBERON:0002423 {source="ZFA"} ! hepatobiliary system relationship: part_of UBERON:0001007 {source="ZFA"} ! digestive system relationship: site_of GO:0002384 ! hepatic immune response relationship: develops_from UBERON:0004161 {source="EHDAA2"} ! septum transversum relationship: develops_from UBERON:0008836 {source="http://www.stembook.org/node/512"} ! liver bud relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: AAO:0010111 ! liver xref: SCTID:181268008 ! Entire liver subset: organ_slim relationship: develops_from UBERON:0003894 {evidence="definitional"} ! liver primordium synonym: "jecur" RELATED LATIN [Wikipedia:Liver] synonym: "iecur" RELATED LATIN [Wikipedia:Liver] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Leber_Schaf.jpg property_value: external_definition "Organ which secretes bile and participates in formation of certain blood proteins.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010111", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: axiom_lost_from_external_ontology "relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010111", date_retrieved="2012-06-20"} property_value: homology_notes "All vertebrates possess a liver (reference 1); Later in craniate evolution, an anterior gill arch was transformed into jaws, and many new types of feeding subsequently evolved.(...) A liver evolved that, among its many functions, stores considerable energy as glycogen or lipid (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000257", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.526\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "hepatic" xsd:string xref: UMLS:C0023884 [Term] id: UBERON:0002426 name: chest muscle def: "A muscle organ that is part of a chest [Automatically generated definition]." [OBOL:automatic] synonym: "musculus thoracicus" EXACT [] synonym: "thoracic muscle" EXACT [] synonym: "anterior thoracic region muscle organ" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax muscle organ" EXACT [OBOL:automatic] synonym: "chest muscle organ" EXACT [OBOL:automatic] synonym: "front of thorax muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of anterior thoracic region" EXACT [OBOL:automatic] synonym: "muscle organ of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "muscle organ of chest" EXACT [OBOL:automatic] synonym: "muscle organ of front of thorax" EXACT [OBOL:automatic] synonym: "muscle of thorax" EXACT [FMA:9619] xref: FMA:9619 ! Muscle of thorax xref: MA:0000548 ! chest muscle xref: BTO:0000508 ! thorax muscle (also: UBERON:0004464 'musculature of thorax') is_a: UBERON:0001774 ! muscle of trunk intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001443 ! chest relationship: part_of UBERON:0001443 ! chest [Term] id: UBERON:0002427 name: arm skin def: "A zone of skin that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "brachial region skin" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb skin" EXACT [OBOL:automatic] synonym: "skin of arm" EXACT [OBOL:automatic] synonym: "skin of brachial region" EXACT [OBOL:automatic] synonym: "skin of proximal segment of free upper limb" EXACT [OBOL:automatic] xref: FMA:37721 ! Skin of arm xref: MA:0000596 ! arm skin xref: ncithesaurus:Arm_Skin ! Arm Skin xref: EMAPA:18062 ! skin of upper arm (also: UBERON:0004263 'upper arm skin') intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm xref: UMLS:C0222204 [Term] id: UBERON:0002428 name: limb bone def: "A bone that is part of a limb [Automatically generated definition]." [OBOL:automatic] comment: AO notes: NCITA includes clavicle. MA:'limb bone' is actually a bone of limb or girdle // Note that the formal definition is very inclusive, and includes sesamoids synonym: "free limb bone" EXACT [UBERON:cjm, UBERONREF:0000003] synonym: "bone of limb" EXACT [OBOL:automatic] synonym: "bone of extremity" EXACT [] xref: EFO:0000880 ! limb bone xref: MAT:0000151 ! limb bone xref: MIAA:0000151 ! limb bone xref: EFO:0000945 ! limb bone xref: ncithesaurus:Bone_of_the_Extremity ! bone of the extremity xref: SCTID:304149004 ! Entire bone of extremity intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0004381 ! skeleton of limb relationship: develops_from UBERON:0010881 ! limb bone cartilaginous condensation xref: UMLS:C0582791 [Term] id: UBERON:0010740 name: bone of appendage girdle complex def: "A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle)." [UBERON:cjm, UBERONREF:0000003] synonym: "bone of extended limb/fin region" RELATED [UBERON:cjm, UBERONREF:0000003] synonym: "limb bone" RELATED [MA:0000688, UBERONREF:0000003] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0010707 ! appendage girdle complex relationship: part_of UBERON:0002091 {notes="UBERONREF:0000003"} ! entire appendicular skeleton xref: MA:0000688 ! limb bone [Term] id: UBERON:0002429 name: cervical lymph node def: "Cervical lymph nodes are lymph nodes found in the neck. [WP,unvetted]." [Wikipedia:Cervical_lymph_node] subset: uberon_slim synonym: "lymph node of neck" EXACT [] xref: FMA:61213 ! Lymph node of neck xref: MA:0000736 ! cervical lymph node xref: ncithesaurus:Cervical_Lymph_Node ! Cervical Lymph Node xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Lymph_node_regions.jpg/200px-Lymph_node_regions.jpg intersection_of: UBERON:0000029 ! lymph node intersection_of: part_of UBERON:0000974 ! neck xref: SCTID:181757009 ! Entire cervical lymph node xref: UMLS:C0588054 [Term] id: UBERON:0002430 name: lateral hypothalamic area def: "The lateral hypothalamus or lateral hypothalamic area is a part of the hypothalamus. It is concerned with hunger. Damage to this area can cause reduced food intake. Stimulating the lateral hypothalamus causes a desire to eat, while stimulating the ventromedial hypothalamus causes a desire to stop eating. [WP,unvetted]." [Wikipedia:Lateral_hypothalamic_area] subset: uberon_slim synonym: "lateral division of hypothalamus" EXACT [] synonym: "lateral group of hypothalamic nuclei" EXACT [] synonym: "lateral hypothalamic group" EXACT [] synonym: "lateral hypothalamic nucleus" RELATED [MA:0000834] synonym: "lateral hypothalamic zone (crosby)" EXACT [] synonym: "lateral hypothalamic region" EXACT [FMA:62030] xref: FMA:62030 ! Lateral hypothalamic region xref: MA:0000834 ! lateral hypothalamic area xref: GAID:640 ! lateral hypothalamic area xref: NIF_GrossAnatomy:birnlex_4037 ! Lateral hypothalamic area xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: MESH:A08.186.211.730.385.357.300 ! lateral hypothalamic area xref: ABA:LHA ! Lateral hypothalamic area xref: BM:Die-Hy-HLA ! lateral hypothalamic area is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0002273 ! lateral zone of hypothalamus relationship: spatially_disjoint_from UBERON:0001931 {source="ABA"} ! lateral preoptic nucleus relationship: spatially_disjoint_from UBERON:0001933 {source="ABA"} ! retrochiasmatic area relationship: spatially_disjoint_from UBERON:0001906 {source="ABA"} ! subthalamic nucleus relationship: spatially_disjoint_from UBERON:0001907 {source="ABA"} ! zona incerta synonym: "area hypothalamica lateralis" EXACT LATIN [FMA:TA, FMA:62030] [Term] id: UBERON:0006964 ! pars distalis of adenohypophysis name: pars distalis of adenohypophysis def: "The distal part of adenohypophysis: the part that makes up the main body of the gland." [Dorlands_Medical_Dictionary:MerckSource, Wikipedia:Pars_distalis] subset: vertebrate_core synonym: "pars distalis adenohypophyseos" RELATED [BTO:0001787] synonym: "pars distalis lobi anterioris hypophyseos" RELATED [BTO:0001787] synonym: "pars anterior of adenohypophysis" EXACT [FMA:74630] synonym: "pars distalis of anterior lobe of pituitary gland" EXACT [FMA:74630] synonym: "pars glandularis of adenohypophysis" EXACT [FMA:74630] synonym: "anterior lobe" RELATED [MA:0000854] synonym: "pars distalis" RELATED [MA:0000854] synonym: "pars glandularis" RELATED [MA:0000854] synonym: "pars anterior" BROAD [MA:0000854, ZFA:0001195, EHDAA2:0001416] xref: FMA:74630 ! pars distalis of adenohypophysis xref: VHOG:0000244 ! pars anterior xref: MA:0000854 ! pars anterior xref: EMAPA:17515 ! pars anterior xref: BTO:0001787 ! pars distalis xref: EHDAA:7532 ! pars anterior xref: ZFA:0001195 ! pars distalis xref: EHDAA2:0001416 ! pars anterior is_a: UBERON:0000483 {source="EHDAA2"} ! epithelium relationship: part_of UBERON:0002196 {source="MA"} ! adenohypophysis synonym: "pars distalis adenohypophysis" EXACT LATIN [FMA:TA, FMA:74630] synonym: "pars distalis (glandula pituitaria)" EXACT LATIN [FMA:TA, FMA:74630] xref: AAO:0010542 ! pars distalis xref: TAO:0001195 ! pars anterior property_value: external_definition "Region of the adenohypophysis which produces the follicle-stimulating hormone, luteinizing hormone, prolactin, thyrotropin, and adrenocorticotropin.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010542", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The anterior part of the adenohypophysis. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000244", date_retrieved="2012-09-17", source="http://www.thefreedictionary.com/pars+anterior", source="http://bgee.unil.ch/"} property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0000244", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002431 name: obsolete pars anterior is_obsolete: true consider: UBERON:0006965 [Term] id: UBERON:0002555 name: intermediate hypothalamic region def: "." [Wikipedia:Pituitary_gland#Intermediate_lobe] comment: See notes for pars intermedia of adenohypophysis synonym: "intermediate hypothalamic area" EXACT [FMA:62028] xref: FMA:62028 ! Intermediate hypothalamic region xref: NIF_GrossAnatomy:birnlex_1015 ! Intermediate hypothalamic region xref: TAO:0006000 ! intermediate hypothalamus is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001898 ! hypothalamus synonym: "area hypothalamica intermedia" EXACT LATIN [FMA:TA, FMA:62028] property_value: external_definition "Brain structure that lies perpendicular to the longitudinal axis of the embryonic neural tube, is continuous with the rostral hypothalamic proliferation and whose most lateral extent is deflected dorsally within the inferior lobe.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0006000", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-001018-1", source="ZFIN:ZDB-PUB-020730-6", source="ZFIN:ZDB-PUB-081114-19"} synonym: "intermediate hypothalamus" RELATED [TAO:0006000] [Term] id: UBERON:0002432 name: pars intermedia of adenohypophysis def: "boundary between the anterior and posterior lobes of the pituitary. It contains three types of cells: basophils, chromophobes, and colloid-filled cysts. The cysts are the remainder of Rathke's pouch. In human fetal life, this area produces melanocyte stimulating hormone or MSH which causes the release of melanin pigment in skin melanocytes (pigment cells). However, the pars intermedia is normally either very small or entirely absent in adulthood. In lower vertebrates (fish, amphibians) MSH from the pars intermedia is responsible for darkening of the skin, often in response to changes in background color. This color change is due to MSH stimulating the dispersion of melanin pigment in dermal (skin) melanophore cells." [Wikipedia:Pars_intermedia] comment: The intermediate part of adenohypophysis: an ill-defined region between the two lobes of the hypophysis; some systems of nomenclature consider it part of the neurohypophysis. In humans a defined structure develops during embryogenesis, but only scattered cells are retained when the gland matures[BTO]. subset: uberon_slim subset: vertebrate_core synonym: "pars intermedia" EXACT [MA:0000855] synonym: "intermediate lobe" RELATED [BTO:0001788] synonym: "intermediate lobe of adenohypophysis" EXACT [] synonym: "intermediate lobe of pituitary" EXACT [] synonym: "pars intermedia adenohypophyseos" RELATED [BTO:0001788] synonym: "pars intermedia lobi anterior hypophyseos" RELATED [BTO:0001788] xref: EHDAA:8765 ! pars intermedia xref: VHOG:0001178 ! pars intermedia xref: MA:0000855 ! pars intermedia xref: ZFA:0001197 ! pars intermedia xref: BTO:0001788 ! pars intermedia xref: EHDAA2:0001417 ! pars intermedia xref: FMA:74632 ! Pars intermedia of adenohypophysis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Gray1181.png/200px-Gray1181.png xref: EMAPA:17516 ! pars intermedia xref: SCTID:245534008 ! Entire pars intermedia of pituitary gland is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002196 {source="ZFA", source="FMA"} ! adenohypophysis relationship: adjacent_to UBERON:0006377 ! remnant of Rathke's pouch relationship: adjacent_to UBERON:0002198 ! neurohypophysis relationship: never_in_taxon NCBITaxon:8782 {source="ISBN10:0471888893"} ! Aves synonym: "pars intermedia adenohypophysis" EXACT LATIN [FMA:TA, FMA:74632] synonym: "pars intermedia (glandula pituitaria)" EXACT LATIN [FMA:TA, FMA:74632] xref: TAO:0001197 ! pars intermedia synonym: "pars intermedia adenohypophyseos" RELATED LATIN [Wikipedia:Pars_intermedia] xref: http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray1181.png synonym: "pars intermedia of anterior lobe of pituitary gland" EXACT [FMA:74632] property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0001178", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002433 name: pars tuberalis of adenohypophysis def: "The pars tuberalis is part of the anterior lobe of the pituitary gland, and wraps the pituitary stalk in a highly vascularized sheath. [WP,unvetted]." [Wikipedia:Pars_tuberalis] subset: uberon_slim subset: vertebrate_core synonym: "pars tuberalis" EXACT [MA:0000856] xref: EHDAA:8767 ! pars tuberalis xref: VHOG:0001114 ! pars tuberalis xref: MA:0000856 ! pars tuberalis xref: BTO:0001739 ! pars tuberalis xref: EHDAA2:0001419 ! pars tuberalis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Pituitary_gland_representation.PNG/200px-Pituitary_gland_representation.PNG xref: EMAPA:17517 ! pars tuberalis xref: FMA:74631 ! Pars tuberalis of adenohypophysis is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002196 ! adenohypophysis relationship: never_in_taxon NCBITaxon:7955 {source="ZFA:0001196"} ! Danio rerio relationship: homologous_to ZFA:0005581 {notes="functional", source="ZFA:0001196"} ! proximal pars anterior synonym: "pars tuberalis adenohypophysis" EXACT LATIN [FMA:TA, FMA:74631] synonym: "pars tuberalis (glandula pituitaria)" EXACT LATIN [FMA:TA, FMA:74631] synonym: "pars tuberalis adenohypophyseos" RELATED LATIN [Wikipedia:Pars_tuberalis] xref: TAO:0001196 ! pars tuberalis xref: http://upload.wikimedia.org/wikipedia/commons/b/b9/Pituitary_gland_representation.PNG synonym: "pars infundibularis of adenohypophysis" EXACT [FMA:74631] synonym: "pars tuberalis of anterior lobe of pituitary gland" EXACT [FMA:74631] property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0001114", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002434 ! pituitary stalk name: pituitary stalk alt_id: UBERON:0003014 ! infundibulum of hypophysis def: "The pituitary stalk (also known as the infundibular stalk or simply the infundibulum) is the connection between the hypothalamus and the posterior pituitary. It carries axons from the magnocellular neurosecretory cells of the hypothalamus down to the posterior pituitary where they release their hormones into the blood. This connection is called the hypothalamohypophyseal tract, and is responsible for the release of oxytocin and antidiuretic hormone[WP]." [Wikipedia:Pituitary_stalk] subset: uberon_slim subset: vertebrate_core synonym: "hypophyseal stalk" EXACT [MP:0009463] synonym: "hypophysial stalk" RELATED [ZFA:0001199] synonym: "infundibulum" EXACT [ZFA:0001199] synonym: "infundibulum of hypothalamus" RELATED [ZFA:0001199] synonym: "infundibular stem" BROAD [MP:0009463] synonym: "infundibular stem of neurohypophysis" EXACT [FMA:74635] synonym: "infundibulum of pituitary gland" EXACT [FMA:74635] synonym: "infundibulum of posterior lobe of pituitary gland" EXACT [FMA:74635] synonym: "neurohypophysis infundibulum" EXACT [FMA:74635] synonym: "tuberal part of hypophysis" EXACT [FMA:74635] synonym: "infundibulum" EXACT [MA:0000858, ZFA:0001199] synonym: "infundibulum of neurohypophysis" EXACT [FMA:74635] xref: MA:0000858 ! infundibulum xref: ncithesaurus:Pituitary_Stalk ! Pituitary Stalk xref: BTO:0000768 ! infundibulum xref: EHDAA2:0000828 ! infundibulum xref: EHDAA:7538 ! infundibulum xref: EMAPA:17520 ! infundibulum of neurohypophysis xref: FMA:74635 ! Infundibulum of neurohypophysis xref: NIF_GrossAnatomy:birnlex_912 ! Tuberal part of hypophysis xref: VHOG:0000245 ! infundibulum xref: ZFA:0001199 ! infundibulum is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002198 ! neurohypophysis relationship: part_of UBERON:0001894 ! diencephalon synonym: "infundibulum (lobus posterior) (glandula pituitaria)" EXACT LATIN [FMA:TA, FMA:74635] synonym: "infundibulum hypophysis" EXACT LATIN [FMA:TA, FMA:74635] xref: SCTID:245529009 ! Entire infundibulum of pituitary gland xref: XAO:0004210 ! infundibulum xref: TAO:0001199 ! infundibulum synonym: "infundibulum neurohypophyseos" RELATED LATIN [Wikipedia:Pituitary_stalk] xref: http://upload.wikimedia.org/wikipedia/commons/b/b9/Pituitary_gland_representation.PNG property_value: external_definition "A short stalk connecting the pituitary with the brain. Axons of secretory cells in the floor of the diencephalon traverse the infundibulum and terminate in the neurohypophysis.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001199", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]" xsd:string {external_class="VHOG:0000245", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.510 and Figure 15-5", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0751440 [Term] id: UBERON:0006250 name: infundibular recess of 3rd ventricle def: "The floor of the third ventricle is prolonged downward as a funnel-shaped recess, the infundibular recess, into the infundibulum, and to the apex of the latter the hypophysis or pititary is attached" [Wikipedia:Infundibular_recess] comment: Editor note: in FMA this is a cavity, whereas in EHDAA2 it is an epithelial sac synonym: "infundibular recess" EXACT [FMA:78456] synonym: "recessus infundibularis" EXACT LATIN [FMA:TA] synonym: "recessus infundibuli" EXACT LATIN [FMA:TA] xref: EMAPA:16648 ! infundibular recess of 3rd ventricle of pituitary of gland of diencephalon of future forebrain xref: EMAPA:16899 ! infundibular recess of 3rd ventricle of pituitary of gland of diencephalon of forebrain xref: EHDAA2:0000827 ! infundibular recess of 3rd ventricle xref: EHDAA:4479 ! infundibular recess of 3rd ventricle xref: SCTID:369280006 ! Entire infundibular recess of third ventricle is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: develops_from UBERON:0003309 {source="EHDAA2"} ! floor plate of diencephalon relationship: part_of UBERON:0000007 {source="EHDAA2"} ! pituitary gland xref: FMA:78456 ! infundibular recess of third ventricle synonym: "recessus infundibuli" RELATED LATIN [Wikipedia:Infundibular_recess] xref: http://upload.wikimedia.org/wikipedia/commons/7/75/Gray654.png synonym: "infundibular recess of third ventricle" EXACT [FMA:78456] [Term] id: UBERON:0000411 name: visual cortex def: "Area of the occipital lobe concerned with vision." [MESH:A08.186.211.730.885.213.571.735] comment: Editor note: merge with primary visual cortex? FMA and BTO treat as distinct synonym: "V1" RELATED [Wikipedia:Visual_cortex] synonym: "striate cortex" RELATED [MESH:A08.186.211.730.885.213.571.735] xref: BTO:0001857 xref: EFO:0000916 ! visual cortex xref: FMA:242644 ! Visual cortex xref: GAID:679 ! visual cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/70/Brodmann_areas_17_18_19.png/200px-Brodmann_areas_17_18_19.png xref: MESH:A08.186.211.730.885.213.571.735 ! visual cortex xref: EV:0100171 ! visual is_a: UBERON:0002619 ! region of cerebral cortex relationship: part_of UBERON:0002021 {source="BTO"} ! occipital lobe [Term] id: UBERON:0002436 name: primary visual cortex def: "The term area 17 of Brodmann (human) refers to a subdivision of the cytoarchitecturally defined occipital region of cerebral cortex in the human. Defined by the band of Gennari, which gives it the name striate (furrowed) area, it occupies the banks of the calcarine sulcus which are located in the cuneus and the lingual gyrus of the occipital lobe. Cytoarchitecturally it is bounded by the area 18 of Brodmann (human) which surrounds it ( Brodmann-1909 ). In the mouse ( Paxinos-2001 ) and the rat ( Swanson-1998 ) it is located on the dorsolateral surface of the cerebral hemisphere[BrainInfo]." [Wikipedia:Visual_cortex, BrainInfo:2102] subset: uberon_slim synonym: "occipital visual neocortex" RELATED [GEO:GSM336648] synonym: "calcarine cortex" RELATED [BrainInfo:2102] synonym: "area striata" RELATED [] synonym: "BA17" RELATED [Wikipedia:Visual_cortex] synonym: "Brodmann area 17" EXACT [Wikipedia:Visual_cortex] synonym: "BA17" EXACT ABBREVIATION [] synonym: "striate cortex" EXACT [FMA:236871] synonym: "V1" RELATED [] synonym: "brodmann (1909) area 17" EXACT [NIF_GrossAnatomy:birnlex_1748] synonym: "b09-17" EXACT [NIF_GrossAnatomy:birnlex_1748] synonym: "Brodmann area 17, striate" EXACT [NIF_GrossAnatomy:birnlex_1748] synonym: "area 17 of brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1748] synonym: "visual association area" RELATED [Wikipedia:Visual_cortex] synonym: "visual association cortex" RELATED [Wikipedia:Visual_cortex] synonym: "area 17 of brodmann" RELATED [Wikipedia:Visual_cortex] synonym: "Brodmann area 17" RELATED [Wikipedia:Visual_cortex] synonym: "BA17" RELATED ABBREVIATION [] xref: FMA:236871 ! Striate cortex xref: MA:0000914 ! primary visual cortex xref: NIF_GrossAnatomy:birnlex_1748 ! Brodmann (1909) area 17 xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/70/Brodmann_areas_17_18_19.png/200px-Brodmann_areas_17_18_19.png xref: BTO:0004703 ! striate cortex xref: BM:Tel-Cx-V1 ! primary visual cortex is_a: UBERON:0002619 ! region of cerebral cortex relationship: part_of UBERON:0002021 ! occipital lobe xref: ncithesaurus:Primary_Visual_Cortex ! primary visual cortex xref: http://upload.wikimedia.org/wikipedia/commons/7/70/Brodmann_areas_17_18_19.png xref: SCTID:384772005 ! Entire Brodmann area 17, striate xref: UMLS:C0038446 [Term] id: UBERON:0011299 alt_id: UBERON:0013202 name: white matter of telencephalon def: "A partion of white matter that is part of a telencephalon. This can be further subdivided in some species, for example, into hemisphere white matter and the corpus callosum." [UBERON:cjm] synonym: "telencephalic tract/commissure" EXACT [ZFA:0000597] synonym: "telencephalic tracts" NARROW [TAO:0000597] intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001893 ! telencephalon xref: FMA:83930 ! white matter of telencephalon xref: ZFA:0000597 ! telencephalic white matter xref: TAO:0000597 ! telencephalic tracts property_value: external_definition "CNS white matter that is part of the telencephalon[ZFA:0000597]." xsd:string {source="ZFA:0000597"} [Term] id: UBERON:0011300 name: gray matter of telencephalon intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: part_of UBERON:0001893 ! telencephalon xref: FMA:83911 ! gray matter of telencephalon def: "A portion of gray matter of neuraxis that is part of a telencephalon." [OBOL:automatic] [Term] id: UBERON:0002437 name: cerebral white matter def: "White matter that is part of a cerebral hemisphere." [UBERON:cjm] comment: Usage notes: sometimes the term 'cerebral white matter' may be used generically but here is refers specifically to the white matter in a hemisphere. AO notes: The BTO class is inconsistent as it is part of the brain and spinal cord. synonym: "hemisphere white matter" RELATED [] synonym: "cerebral hemisphere white matter" EXACT [] xref: BTO:0000236 xref: FMA:241998 ! Cerebral white matter xref: MA:0000945 ! cerebral white matter xref: ncithesaurus:Cerebral_White_Matter ! Cerebral White Matter xref: NIF_GrossAnatomy:birnlex_711 ! Cerebral white matter intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001869 ! cerebral hemisphere xref: SCTID:361691006 ! Entire cerebral white matter xref: UMLS:C0152295 [Term] id: UBERON:0005401 name: cerebral grey matter comment: AO notes: BTO may actually be a more generic structure; FMA may represent a more specific structure. Consider merging with gray matter of telencephalon synonym: "cerebral gray matter" EXACT [BTO:0000823] xref: MA:0000944 ! cerebral grey matter xref: BTO:0000823 ! cerebral gray matter xref: FMA:61821 ! gray matter structure of cerebral hemisphere intersection_of: UBERON:0003528 ! brain grey matter intersection_of: part_of UBERON:0001869 ! cerebral hemisphere [Term] id: UBERON:0002438 name: ventral tegmental nucleus comment: AO notes: ventral and anterior tegmental nucleus are synonyms in FMA, but we split these into seperate classes. This is consistent with MA, ABA and neuronames, which treat these as distinct (NN suggest the anterior is a rodent specific structure). Location notes: this is part of pons and brainstem in MA, but this leads to an inconsistency with ABA. We err on the side of safety, and exclude the relationship to the pons here. subset: vertebrate_core synonym: "nucleus of Gudden" RELATED [MA:0001031] synonym: "anterior tegmental nuclei" RELATED INCONSISTENT [FMA:72435] synonym: "anterior tegmental nucleus" RELATED INCONSISTENT [FMA:72435, http://www.medilexicon.com/medicaldictionary.php?t=61761] synonym: "deep tegmental nucleus of Gudden" EXACT [FMA:72435] synonym: "nucleus tegmentales anteriores" RELATED [FMA:TA] synonym: "nucleus tegmentalis anterior" RELATED [FMA:TA] synonym: "ventral raphe tegmental nucleus" EXACT [FMA:72435] synonym: "ventral tegmental nuclei" EXACT [FMA:72435] synonym: "ventral tegmental nucleus (gudden)" EXACT [FMA:72435] synonym: "ventral tegmental nucleus of gudden" EXACT [FMA:72435] xref: FMA:72435 ! Ventral tegmental nucleus xref: MA:0001031 ! ventral tegmental nucleus xref: NIF_GrossAnatomy:birnlex_1421 ! Ventral tegmental nucleus xref: ZFA:0000275 ! rostral tegmental nucleus xref: ABA:VTN ! Ventral tegmental nucleus xref: SCTID:369244006 ! Entire ventral tegmental nuclei of midbrain is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 {source="NIF"} ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area xref: TAO:0000275 ! rostral tegmental nucleus synonym: "rostral tegmental nucleus" RELATED [TAO:0000275] [Term] id: UBERON:0010036 name: anterior tegmental nucleus def: "a group of cells located ventral to the decussation of the superior cerebellar peduncle in the mouse ( Paxinos-2001 ) and rat ( Swanson-1998 )" [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=1115] is_a: UBERON:0006331 {source="MA"} ! brainstem nucleus relationship: part_of UBERON:0001891 {source="MA", source="ABA"} ! midbrain xref: MA:0001055 ! anterior tegmental nucleus xref: ABA:AT ! Anterior tegmental nucleus disjoint_from: UBERON:0002438 ! ventral tegmental nucleus relationship: only_in_taxon NCBITaxon:9989 {source="NN"} ! Rodentia [Term] id: UBERON:0000429 ! enteric plexus alt_id: UBERON:0012372 name: enteric plexus def: "A plexus of autonomic nerve fibers within the wall of the digestive tube, and made up of the submucosal, myenteric, and subserosal plexuses; it contains visceral afferent fibers, sympathetic postganglionic fibers, parasympathetic preganglionic and postganglionic fibers, and parasympathetic postganglionic cell bodies." [BTO:0002437] synonym: "plexus entericus" EXACT [BTO:0002437] synonym: "enteric nerve plexus" EXACT [FMA:77597] synonym: "sympathetic enteric nerve plexus" EXACT [FMA:77597] synonym: "intrinsic nerve plexus" EXACT [MA:0001147] synonym: "plexus nervosus entericus" EXACT LATIN [FMA:TA, FMA:77597] xref: BTO:0002437 xref: FMA:77597 ! Enteric plexus xref: MA:0001147 ! intrinsic nerve plexus is_a: UBERON:0001816 ! autonomic nerve plexus intersection_of: UBERON:0001810 ! nerve plexus intersection_of: part_of UBERON:0002005 ! enteric nervous system [Term] id: UBERON:0012374 name: subserosal plexus def: "The subserous part of the enteric plexus of autonomic nerves" [http://medical-dictionary.thefreedictionary.com/subserous+plexus] synonym: "subserous nerve plexus" EXACT [FMA:77598] synonym: "subserous plexus" EXACT [FMA:77598] synonym: "tela subserosa" EXACT [] is_a: UBERON:0000429 ! enteric plexus relationship: part_of UBERON:0012375 ! subserosa xref: FMA:77598 ! subserous plexus xref: SCTID:110699000 ! Subserosal plexus [Term] id: UBERON:0012375 ! subserosa name: subserosa def: "a layer of tissue between the muscularis and serosa." [Wikipedia:Subserosa] is_a: UBERON:0004923 {source="FMA"} ! organ component layer xref: FMA:45636 ! subserosa xref: ncithesaurus:Subserosa ! subserosa xref: SCTID:2255006 ! Subserosa xref: UMLS:C0225334 [Term] id: UBERON:0002439 name: myenteric nerve plexus def: "plexus of unmyelinated nerve fibers and postganglionic autonomic cell bodies lying in the muscular coat of the esophagus, stomach and intestines that communicate with the submucosal, subserosal and enteric plexuses[MP]. Part of the enteric nervous system, Auerbach's plexus (or myenteric plexus) exists between the longitudinal and circular layers of muscularis externa in the gastrointestinal tract and provides motor innervation to both layers and secretomotor innervation to the mucosa, having both parasympathetic and sympathetic input, whereas Meissner's plexus has only parasympathetic fibers. It arises from cells in the Nucleus ala cinerea, the parasympathetic nucleus of origin for the tenth cranial nerve, located in the medulla oblongata. The fibers are carried by both the anterior and posterior vagal nerves. It is found in the muscles of the esophagus, stomach, and intestine. The myenteric plexus is the major nerve supply to the gastrointestinal tract and control GI tract motility[WP]." [Wikipedia:Auerbach's_plexus, MP:0010801] comment: AO notes: note that FMA uses Meissner's plexus as a synonym, rather than separate class subset: uberon_slim synonym: "Auerbach's plexus" EXACT [FMA:63252, HP:0002251] synonym: "Meissner's plexus" RELATED INCONSISTENT [FMA:63252] synonym: "myenteric plexus" EXACT [] synonym: "Remak's plexus" EXACT [FMA:63252] synonym: "submucous plexus" RELATED [] synonym: "Auberbach plexus" EXACT [NIF_GrossAnatomy:nlx_anat_100306] synonym: "Auberbach's plexus" EXACT [NIF_GrossAnatomy:nlx_anat_100306] synonym: "Auberbachs plexus" EXACT [NIF_GrossAnatomy:nlx_anat_100306] synonym: "plexus myentericus" RELATED [BTO:0002436] xref: FMA:63252 ! Myenteric nerve plexus xref: MA:0001148 ! myenteric nerve plexus xref: BTO:0002436 ! myenteric plexus xref: GAID:798 ! myenteric plexus xref: NIF_GrossAnatomy:nlx_anat_100306 ! Myenteric Plexus xref: MESH:A08.800.050.050.500 ! myenteric plexus is_a: UBERON:0000429 ! enteric plexus relationship: part_of UBERON:0012367 {source="FMA"} ! muscle layer of intestine relationship: has_function_in GO:0030432 ! peristalsis synonym: "plexus nervosus submucosus" EXACT LATIN [FMA:TA, FMA:63252] synonym: "plexus submucosus" EXACT LATIN [FMA:TA, FMA:63252] xref: ncithesaurus:Myenteric_Nerve_Plexus ! Myenteric Nerve Plexus xref: SCTID:267716001 ! Entire Auerbach's plexus xref: UMLS:C0027028 [Term] id: UBERON:0005304 name: submucous nerve plexus def: "The nerves of the small intestines are derived from the plexuses of parasympathetic nerves around the superior mesenteric artery. From this source they run to the myenteric plexus of nerves and ganglia situated between the circular muscular fibers and the mucosal cells. From this a secondary plexus, the plexus of the submucosa (Meissner's plexus, Submucous plexus, submucosal plexus) is derived, and it is formed by branches that have perforated the circular muscular fibers. This plexus lies in the submucous coat of the intestine; it also contains ganglia from which nerve fibers pass to the muscularis mucosae and to the mucous membrane. The nerve bundles of the submucous plexus are finer than those of the myenteric plexus. Its function is to innervate cells in the epithelial layer and the smooth muscle of the[WP]." [Wikipedia:Meissner's_plexus] comment: AO notes: in FMA this is part of the esophagus, duodenum and intestine; this violates part-disjointness axioms in uberon synonym: "Henle's plexus" RELATED [MA:0001149] synonym: "meissner's plexus" RELATED [MA:0001149] synonym: "Meissner's plexus" RELATED [MA:0001149, HP:0002251] synonym: "submucosal nerve plexus" EXACT [FMA:21542, Wikipedia:Meissner's_plexus] xref: MA:0001149 ! submucous nerve plexus xref: FMA:21542 ! submucosal nerve plexus xref: GAID:801 ! submucous plexus xref: MESH:A08.800.050.050.850 ! submucous plexus is_a: UBERON:0000429 ! enteric plexus relationship: overlaps UBERON:0001974 {source="FMA-modified"} ! lamina propria of esophagus relationship: overlaps UBERON:0001205 {source="FMA-modified"} ! submucosa of small intestine xref: ncithesaurus:Submucous_Nerve_Plexus ! Submucous Nerve Plexus xref: SCTID:322349001 ! Entire Meissner's plexus xref: UMLS:C0038564 [Term] id: UBERON:0001816 name: autonomic nerve plexus def: "A nerve plexus that is part of an autonomic nervous system [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "autonomic plexus" EXACT [] synonym: "visceral nerve plexus" EXACT [] synonym: "visceral plexus" EXACT [] xref: FMA:5910 ! Autonomic nerve plexus xref: MA:0000221 ! autonomic nerve plexus xref: EMAPA:18224 ! nerve plexus of autonomic intersection_of: UBERON:0001810 ! nerve plexus intersection_of: part_of UBERON:0002410 ! autonomic nervous system synonym: "plexus nervosus visceralis" EXACT LATIN [FMA:TA, FMA:5910] synonym: "plexus visceralis" EXACT LATIN [FMA:TA, FMA:5910] synonym: "plexus autonomicus" EXACT LATIN [FMA:TA, FMA:5910] xref: SCTID:362482000 ! Entire autonomic plexus [Term] id: UBERON:0012373 name: sympathetic nerve plexus intersection_of: UBERON:0001810 ! nerve plexus intersection_of: part_of UBERON:0000013 ! sympathetic nervous system xref: MA:0001160 ! sympathetic nerve plexus [Term] id: UBERON:0002440 name: inferior cervical ganglion def: "The inferior cervical ganglion is situated between the base of the transverse process of the last cervical vertebra and the neck of the first rib, on the medial side of the costocervical artery. Its form is irregular; it is larger in size than the middle cervical ganglion, and is frequently fused with the first thoracic ganglion. [WP,unvetted]." [Wikipedia:Inferior_cervical_ganglion] subset: uberon_slim synonym: "stellate ganglion" RELATED [MA:0001154] synonym: "variant cervical ganglion" EXACT [] synonym: "ganglion cervicale inferioris" RELATED [BTO:0000240] xref: BTO:0000240 xref: EHDAA:8939 ! inferior cervical ganglion xref: FMA:6961 ! Inferior cervical ganglion xref: MA:0001154 ! inferior cervical ganglion xref: RETIRED_EHDAA2:0000815 ! inferior cervical ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e1/Gray844.png/200px-Gray844.png xref: EMAPA:18439 ! inferior of cervical is_a: UBERON:0001991 ! cervical ganglion xref: SCTID:279280008 ! Entire inferior cervical ganglion xref: ncithesaurus:Inferior_Cervical_Ganglion ! inferior cervical ganglion synonym: "ganglion cervicale inferius" RELATED LATIN [Wikipedia:Inferior_cervical_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/e/e1/Gray844.png xref: UMLS:C0229000 [Term] id: UBERON:0002441 name: cervicothoracic ganglion def: "The stellate ganglion (or cervicothoracic ganglion) is a sympathetic ganglion formed by the fusion of the inferior cervical ganglion and the first thoracic ganglion. Stellate ganglion is located at the level of C7, anterior to the transverse process of C7, posterior to the neck of the first rib, and just below the subclavian artery. [WP,unvetted]." [Wikipedia:Cervicothoracic_ganglion] subset: uberon_slim synonym: "cervicothoracic sympathetic ganglion" EXACT [] synonym: "stellate ganglion" EXACT [] xref: FMA:6469 ! Cervicothoracic ganglion xref: MA:0001157 ! cervicothoracic ganglion xref: BTO:0001815 ! stellate ganglion xref: GAID:711 ! stellate ganglion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7a/Gray845.png/200px-Gray845.png xref: EMAPA:18226 ! cervico-thoracic xref: MESH:A08.340.315.350.800 ! stellate ganglion is_a: UBERON:0001991 ! cervical ganglion relationship: part_of UBERON:0001991 ! cervical ganglion synonym: "ganglion stellatum" EXACT LATIN [FMA:TA, FMA:6469] xref: SCTID:181101006 ! Entire stellate ganglion [Term] id: UBERON:0002442 name: axillary nerve trunk synonym: "circumflex nerve trunk" RELATED [MA:0001175] synonym: "right axillary neural trunk" EXACT [] synonym: "trunk of right axillary nerve" EXACT [FMA:65265] xref: FMA:65265 ! Trunk of right axillary nerve xref: MA:0001175 ! axillary nerve trunk is_a: UBERON:0001147 ! trunk of peripheral nerve [Term] id: UBERON:0002443 name: choroidal blood vessel def: "A blood vessel that is part of a choroid [Automatically generated definition]." [OBOL:automatic] comment: cannot find singular in FMA, using Set class synonym: "choroid blood vessels" EXACT [] synonym: "choroid blood vessels set" EXACT [] synonym: "blood vessel of choroid" EXACT [OBOL:automatic] synonym: "blood vessel of choroid coat" EXACT [OBOL:automatic] synonym: "blood vessel of choroidea" EXACT [OBOL:automatic] synonym: "blood vessel of posterior uvea" EXACT [OBOL:automatic] synonym: "choroid blood vessel" EXACT [OBOL:automatic] synonym: "choroid coat blood vessel" EXACT [OBOL:automatic] synonym: "choroidea blood vessel" EXACT [OBOL:automatic] synonym: "posterior uvea blood vessel" EXACT [OBOL:automatic] xref: FMA:76550 ! Set of choroid blood vessels xref: MA:0001237 ! choroidal blood vessel xref: EMAPA:17828 ! choroidal blood vessels is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001776 ! optic choroid relationship: part_of UBERON:0001776 ! optic choroid synonym: "vasa sanguinea choroideae" EXACT LATIN [FMA:TA, FMA:76550] synonym: "set of choroid blood vessels" RELATED [FMA:76550] [Term] id: UBERON:0002445 name: ulnare def: "The postaxial bone of the proximal carpal region. Found in close approximation to the ulna, often in articulation[PHENOSCAPE:ad]." [Wikipedia:Triquetral] comment: note this bone is termed the triquetral bone in some mammalian taxa, notably humans subset: uberon_slim synonym: "cuneiform bone of hand" EXACT [] synonym: "cuneiform bone of manus" EXACT [] synonym: "cuneiform of hand" RELATED [MA:0001347] synonym: "triangular" RELATED [MA:0001347] synonym: "triangular bone" EXACT [] synonym: "triquetral bone" EXACT [] synonym: "triquetrum" RELATED [MA:0001347] synonym: "ulnar carpal bone" RELATED [MA:0001347] synonym: "triquetral" EXACT [MA:0001347, NCBITaxon:9606] synonym: "os triquetrum" EXACT LATIN [FMA:TA, FMA:23715] synonym: "os ulnare" EXACT [UBERON:cjm] xref: FMA:23715 ! Triquetral xref: MA:0001347 ! triquetral xref: AAO:0000845 ! ulnare xref: ncithesaurus:Triangular_Bone ! Triangular Bone xref: galen:Triquetral ! triquetral xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/50/Carpus.png/200px-Carpus.png is_a: UBERON:0001480 ! proximal carpal bone relationship: postaxial_part_of UBERON:0009880 ! carpal skeleton intersection_of: UBERON:0001480 ! proximal carpal bone intersection_of: proximally_connected_to UBERON:0001424 ! ulna relationship: connected_to UBERON:0001429 {gci_relation="part_of", gci_filler="NCBITaxon:9606", connected_by="UBERON:0011870 or UBERON:0011869", source="Wikipedia"} ! pisiform relationship: connected_to UBERON:0001428 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="Wikipedia"} ! lunate relationship: connected_to UBERON:0001433 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="Wikipedia", notes="hamate"} ! distal carpal bone 4 relationship: connected_to UBERON:0001424 {gci_relation="part_of", gci_filler="NCBITaxon:8292", source="Wikipedia", source="AAO", notes="Amphibia"} ! ulna xref: SCTID:181965000 ! Entire triangular bone property_value: external_definition "One of two element that constitute the basal row of carpals. It articulates with the ulna, radius, radiale, centrale (element Y), and carpal 5(4). This element originates from one condensation center or the fusion of two elements (ulnare and intermedium). Occasionally it may fuse to carpal 5(4), the radiale, or other elements.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000845", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0223739 [Term] id: UBERON:0002447 name: palatine gland def: "The palatine glands form a continuous layer on its posterior surface and around the uvula. They are primarily mucous secreting glands, as opposed to serous or mixed secreting glands. [WP,unvetted]." [Wikipedia:Palatine_glands] subset: uberon_slim synonym: "salivary palatine gland" EXACT [] synonym: "palatine salivary gland" EXACT [] synonym: "palatine glands set" EXACT [] xref: FMA:59795 ! palatine salivary gland xref: MA:0001584 ! palatine gland xref: ncithesaurus:Palatine_Salivary_Gland ! Palatine Salivary Gland is_a: UBERON:0001830 ! minor salivary gland xref: SCTID:13604002 ! Palatine gland xref: UMLS:C0930557 [Term] id: UBERON:0009471 name: dorsum of tongue def: "the superior surface of the tongue divided by the sulcus terminalis into an anterior two-thirds, the presulcal part (pars presulcalis). and a posterior one-third, the postsulcal part (pars postsulcalis)." [http://www.drugs.com/dict/dorsum-of-tongue.html] synonym: "dorsal tongue" EXACT [FMA:54651] synonym: "tongue dorsum" EXACT [FMA:54651] synonym: "dorsum linguae" EXACT [http://www.drugs.com/dict/dorsum-of-tongue.html] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001723 {source="FMA"} ! tongue xref: FMA:54651 ! dorsum of tongue xref: SCTID:66938003 ! Structure of dorsum of tongue xref: ncithesaurus:Dorsum_of_the_Tongue ! Dorsum of the Tongue xref: UMLS:C0226952 [Term] id: UBERON:0002448 ! fungiform papilla name: fungiform papilla def: "The fungiform papillae are mushroom shaped e (projections) on the tongue. They are located on the top (dorsal) surface of the tongue, scattered throughout the filiform papilla but mainly at the tip and lateral margins of the tongue. They have taste buds on their superior (upper) surface which can distinguish the five tastes: sweet, sour, bitter, salty, and umami. They have a core of connective tissue. They are innervated by the seventh cranial nerve, more specifically via the submandibular ganglion, chorda tympani, and geniculate ganglion ascending to the solitary nucleus (the sensory component of the Vagus nerve in the brainstem). [WP,unvetted]." [Wikipedia:Fungiform_papilla] subset: uberon_slim synonym: "fungiform papillae" EXACT PLURAL [] synonym: "fungiform papillae set" EXACT PLURAL [] synonym: "fungiform papilla of tongue" EXACT [FMA:54821] xref: FMA:54821 ! fungiform papilla of tongue xref: MA:0001595 ! fungiform papilla xref: ncithesaurus:Fungiform_Papilla ! Fungiform Papilla xref: NIF_GrossAnatomy:birnlex_4106 ! Fungiform papilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Gray1014.png/200px-Gray1014.png xref: EMAPA:18657 ! fungiform papillae of epithelium of tongue of pharynx of foregut is_a: UBERON:0001726 {source="MA"} ! papilla of tongue xref: SCTID:80673002 ! Entire fungiform papillae of tongue synonym: "papillae fungiformes" RELATED LATIN [Wikipedia:Fungiform_papilla] xref: http://upload.wikimedia.org/wikipedia/commons/6/6e/Gray1014.png xref: UMLS:C0545784 [Term] id: UBERON:0002451 name: uterine gland def: "tube like gland lined by ciliated columnar epithelium[WP]. The mucous secreting gland associated with the epithelium lining the uterus. These glands develop and secrete each menstrual cycle and are thought to provide initial blastocyst nutrition prior to implantation[BTO]" [Wikipedia:Uterine_glands] comment: todo - check FMA subset: uberon_slim synonym: "uterine glands" EXACT [] synonym: "uterine glands set" EXACT [] xref: FMA:71647 ! Set of uterine glands xref: FMA:86488 ! glandular part of endometrium xref: MA:0001726 ! uterine gland xref: ncithesaurus:Uterine_Gland ! Uterine Gland xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/28/Gray1169.png/200px-Gray1169.png xref: BTO:0004518 ! uterine gland xref: EMAPA:29919 ! uterine gland xref: SCTID:361377009 ! Entire endometrial gland xref: BTO:0003433 ! endometrial gland is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0000995 ! uterus relationship: has_part UBERON:0007592 {source="Wikipedia"} ! ciliated columnar epithelium relationship: has_quality PATO:0001873 {source="Wikipedia:Tubular_gland"} ! cylindrical synonym: "glandulae uterinae" EXACT LATIN [FMA:TA, FMA:71647] subset: organ_slim synonym: "glandulae uterinae" RELATED LATIN [Wikipedia:Uterine_glands] xref: http://upload.wikimedia.org/wikipedia/commons/2/28/Gray1169.png synonym: "set of uterine glands" RELATED [FMA:71647] synonym: "glandular part of endometrium" RELATED [FMA:86488] xref: UMLS:C1183035 [Term] id: UBERON:0000428 name: prostate epithelium alt_id: UBERON:0002452 def: "the prostate epithelium." [MP:0001168] comment: TODO - check 2 FMA IDs synonym: "prostate gland epithelium" EXACT [] synonym: "prostatic gland epithelium" EXACT [] synonym: "epithelial tissue of prostate" EXACT [OBOL:automatic] synonym: "epithelial tissue of prostate gland" EXACT [OBOL:automatic] synonym: "epithelium of prostate" EXACT [OBOL:automatic] synonym: "epithelium of prostate gland" EXACT [OBOL:automatic] synonym: "prostate epithelial tissue" EXACT [OBOL:automatic] synonym: "prostate gland epithelial tissue" EXACT [OBOL:automatic] synonym: "prostatic epithelium" EXACT [FMA:66812] synonym: "epithelium of prostatic gland" EXACT [FMA:79643] xref: BTO:0002397 xref: FMA:66812 ! Prostatic epithelium xref: FMA:79643 ! Epithelium of prostatic gland xref: MA:0001737 ! prostate gland epithelium xref: ncithesaurus:Prostatic_Epithelium ! Prostatic Epithelium is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002367 ! prostate xref: UMLS:C1179826 [Term] id: UBERON:0009843 ! prostate epithelial cord name: prostate epithelial cord def: "A solid cord of prostate epithelium." [PMID:18977204, GO:0060527, OBOL:automatic] synonym: "epithelial cord of prostate" EXACT [] synonym: "cord of prostate epithelium" EXACT [PMID:18977204] comment: Complexity is conferred on the prostate during a postnatal development phase known as branching morphogenesis. Solid cords of prostate epithelium formed in utero elongate postnatally and their tips are bifurcated into primary, secondary, and tertiary branches in a pattern that is unique for each prostate lobe. Branching morphogenesis proceeds differentially for each of the three mouse prostate lobes (ventral, dorsolateral, and anterior) and is completed by about postnatal day 20 in mice, providing each lobe with unique glandular architecture [5]. It is important to note that the developing human prostate undergoes a similar series of morphogenetic events especially during prostatic bud formation, but gives rise to a mature glandular prostate that is unique from the rodent and features peripheral, central, and transitional zones[PMID:18977204] intersection_of: UBERON:0005154 ! epithelial cord intersection_of: part_of UBERON:0002367 ! prostate [Term] id: UBERON:0002453 name: ethmoid sinus def: "The ethmoid sinus, one of the paranasal sinuses, is the collective name for the ethmoidal air cells. Each ethmoid sinus is an air-space enclosed within the ethmoid bone. The ethmoidal air cells consist of numerous thin-walled cavities situated in the ethmoidal labyrinth and completed by the frontal, maxilla, lacrimal, sphenoidal, and palatine bones. They lie between the upper parts of the nasal cavities and the orbits, and are separated from these cavities by thin bony laminæ. [WP,unvetted]." [Wikipedia:Ethmoid_bone_sinus] subset: uberon_slim synonym: "ethmoidal sinus" EXACT [FMA:84115] xref: FMA:84115 ! Ethmoidal sinus xref: MA:0001792 ! ethmoid sinus xref: ncithesaurus:Ethmoid_Sinus xref: GAID:356 ! ethmoid sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Nnh_front.svg/200px-Nnh_front.svg.png xref: MESH:A04.531.621.267 ! ethmoid sinus is_a: UBERON:0001825 ! paranasal sinus xref: SCTID:181206009 ! Entire ethmoid sinus synonym: "cellulae ethmoidales" RELATED LATIN [Wikipedia:Ethmoid_sinus] xref: UMLS:C0015028 [Term] id: UBERON:0002454 name: dorsal metacarpal artery def: "Aanastomosis of dorsal carpal branch of the radial artery and the dorsal carpal branch of the ulnar artery near the back of the wrist. It is made up of the dorsal carpal branches of both the ulnar and radial arteries. It also anastomoses with the anterior interosseous artery and the posterior interosseous artery. The arch gives off three dorsal metacarpal arteries." [Wikipedia:Dorsal_metacarpal_artery] comment: check FMA, singular. specific subtypes e.g. FMA:22761 first dorsal metacarpal artery subset: uberon_slim synonym: "dorsal metacarpal arteries" EXACT [] synonym: "dorsal metacarpal arteries set" EXACT [] xref: FMA:70800 ! set of dorsal metacarpal arteries xref: MA:0001944 ! dorsal metacarpal artery xref: ncithesaurus:Dorsal_Metacarpal_Artery ! Dorsal Metacarpal Artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray529.png/200px-Gray529.png is_a: UBERON:0001637 ! artery synonym: "arteriae metacarpales dorsales" EXACT LATIN [FMA:TA, FMA:70800] xref: SCTID:244320002 ! Entire dorsal metacarpal artery synonym: "set of dorsal metacarpal arteries" RELATED [FMA:70800] xref: UMLS:C0447094 [Term] id: UBERON:0002456 name: internal thoracic artery def: "In human anatomy, the internal thoracic artery (ITA), previously known as the internal mammary artery (a name still common among surgeons), is an artery that supplies the anterior chest wall and the breasts. It is a paired artery, with one running along each side of the sternum, to continue after its bifurcation as the superior epigastric and musculophrenic arteries. [WP,unvetted]." [Wikipedia:Internal_thoracic_artery] comment: note MA has both mammary and thoracic subset: uberon_slim synonym: "internal mammary artery" EXACT ATTRIBUTION_REQUIRED [MA:0001982] synonym: "internal thoracic mammary artery" EXACT [] xref: EHDAA:8585 ! internal thoracic artery xref: FMA:3960 ! Internal thoracic artery xref: MA:0001984 ! internal thoracic artery xref: MA:0001982 ! internal mammary artery xref: OpenCyc:Mx4rMe0MIao8EduQrwACs5b6Bw xref: ncithesaurus:Internal_Mammary_Artery ! Internal Mammary Artery xref: OpenCyc:Mx4rMe0MIao8EduQrwACs5b6Bw ! internal thoracic artery xref: EHDAA2:0000880 ! internal thoracic artery xref: EMAPA:18617 ! internal thoracic artery is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0001533 ! subclavian artery relationship: part_of UBERON:0001533 ! subclavian artery xref: SCTID:244239009 ! Entire internal thoracic artery synonym: "arteria thoracica interna, arteria mammaria interna" RELATED LATIN [Wikipedia:Internal_thoracic_artery] xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray522.png xref: UMLS:C0226276 [Term] id: UBERON:0002457 name: intersegmental artery subset: vertebrate_core synonym: "7th intersegmental artery" EXACT [] synonym: "seventh intersegmental artery" EXACT [] xref: EHDAA:4340 ! intersegmental artery xref: VHOG:0000225 ! intersegmental artery xref: MA:0001985 ! intersegmental artery xref: ZFA:0001061 ! intersegmental artery xref: EHDAA2:0000882 ! intersegmental artery xref: EMAPA:17616 ! intersegmental artery xref: SCTID:338130007 ! Entire seventh intersegmental artery is_a: UBERON:0001637 ! artery xref: TAO:0001061 ! intersegmental artery property_value: homology_notes "Few changes of evolutionary significance occur in the branching pattern of the dorsal aorta. All vertebrates have (...) paired intersegmental arteries to the trunk, tail, and paired appendages.[well established][VHOG]" xsd:string {external_class="VHOG:0000225", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.612", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002459 name: inferior palpebral vein comment: check FMA, singular. synonym: "inferior palpebral veins" EXACT [] synonym: "inferior palpebral veins set" EXACT [] synonym: "lower palpebral vein" RELATED [MA:0002147] xref: FMA:70847 ! Set of inferior palpebral veins xref: MA:0002147 ! inferior palpebral vein xref: ncithesaurus:Inferior_Palpebral_Vein ! Inferior Palpebral Vein is_a: UBERON:0001638 ! vein synonym: "venae palpebrales inferiores" EXACT LATIN [FMA:TA, FMA:70847] xref: SCTID:422559003 ! Structure of inferior palpebral vein synonym: "set of inferior palpebral veins" RELATED [FMA:70847] xref: UMLS:C1760539 [Term] id: UBERON:0002460 name: vesical vein def: "The vesical veins are tributaries of the internal iliac veins. [WP,unvetted]." [Wikipedia:Vesical_veins] comment: check FMA, singular. subset: uberon_slim synonym: "vesical veins" EXACT [] synonym: "vesical veins set" EXACT [] xref: FMA:70911 ! Set of vesical veins xref: MA:0002263 ! vesical vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Gray585.png/200px-Gray585.png is_a: UBERON:0001638 ! vein synonym: "venae vesicales" EXACT LATIN [FMA:TA, FMA:70911] xref: SCTID:12683000 ! Entire vesical vein xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png synonym: "set of vesical veins" RELATED [FMA:70911] [Term] id: UBERON:0002461 name: anterior abdominal wall muscle synonym: "muscle of anterior abdominal wall" EXACT [FMA:20278] xref: FMA:20278 ! Muscle of anterior abdominal wall xref: MA:0002268 ! anterior abdominal wall muscle xref: ncithesaurus:Anterior_Abdominal_Wall_Muscle ! Anterior Abdominal Wall Muscle xref: EHDAA2:0000125 ! anterior abdominal wall muscle system is_a: UBERON:0002378 {source="FMA"} ! muscle of abdomen intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0006635 ! anterior abdominal wall def: "A muscle organ that is part of a anterior abdominal wall." [OBOL:automatic] xref: UMLS:C1744565 [Term] id: UBERON:0002462 name: erector spinae muscle group def: "A bundle of muscles and tendons that is paired and runs more or less vertically. It extends throughout the lumbar, thoracic and cervical regions, and lies in the groove to the side of the vertebral column." [Wikipedia:Erector_spinae_muscles] comment: AO notes: isa muscle organ in MA. subset: uberon_slim synonym: "erector spinae" EXACT [MA:0002289] synonym: "extensor spinae muscles" EXACT [Wikipedia:Erector_spinae] synonym: "extensor spinae muscle" RELATED [Wikipedia:Erector_spinae] synonym: "extensor spinae" EXACT [Wikipedia:Erector_spinae] synonym: "sacrospinalis" EXACT DEPRECATED [BTO:0001652] xref: FMA:71302 ! Erector spinae muscle group xref: VHOG:0000984 ! erector spinae xref: MA:0002289 ! erector spinae xref: ncithesaurus:Erector_Spinae ! Erector Spinae xref: EHDAA:9456 ! erector spinae xref: OpenCyc:Mx4rwC7lnJwpEbGdrcN5Y29ycA ! erector spinae xref: EHDAA2:0000454 ! erector spinae xref: BTO:0001652 ! sacrospinalis xref: EMAPA:18168 ! erector spinae xref: SCTID:244852007 ! Entire erector spinae muscle is_a: UBERON:0001015 {source="FMA"} ! musculature is_a: UBERON:0003897 {source="EHDAA2"} ! axial muscle relationship: develops_from UBERON:0010961 {source="EHDAA2"} ! erector spinae pre-muscle mass relationship: adjacent_to UBERON:0001130 ! vertebral column relationship: innervated_by UBERON:0006839 {source="dbpedia"} ! posterior ramus of spinal nerve synonym: "m. erector spinae" RELATED LATIN [Wikipedia:Erector_spinae_muscles] relationship: has_muscle_insertion UBERON:0001076 {source="dbpedia", notes="Spinous processes of T1 and T2 thoracic vertebrae and the cervical vertebrae"} ! spinous process of vertebra relationship: has_muscle_insertion UBERON:0002413 {source="dbpedia", notes="Spinous processes of T1 and T2 thoracic vertebrae and the cervical vertebrae"} ! cervical vertebra xref: http://upload.wikimedia.org/wikipedia/commons/d/de/Gray1124.png xref: UMLS:C0224301 [Term] id: UBERON:0010961 name: erector spinae pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: part_of UBERON:0003897 {source="EHDAA2"} ! axial muscle relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group xref: EHDAA2:0000455 ! erector spinae pre-muscle mass [Term] id: UBERON:0002464 name: nerve trunk synonym: "trunk of nerve" EXACT [] subset: vessel_or_tree xref: BTO:0000927 xref: EHDAA:4675 ! nerve trunk xref: FMA:5913 ! Nerve trunk xref: MA:0002408 ! nerve trunk xref: EMAPA:16986 ! nerve trunk (also: UBERON:0001147 'trunk of peripheral nerve') (also: UBERON:0003439 'nerve of trunk region') (also: UBERON:0004295 'sympathetic nerve trunk') is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001016 ! nervous system xref: SCTID:281248001 ! Nervous structure of trunk [Term] id: UBERON:0002466 name: intestine secretion def: "Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine." [Wikipedia:Succus_entericus] subset: uberon_slim synonym: "succus entericus" EXACT [] synonym: "intestinal secretion" EXACT [FMA:62974] xref: FMA:62974 ! Intestinal secretion xref: MA:0002515 ! intestine secretion xref: ncithesaurus:Intestinal_Secretion ! Intestinal Secretion xref: GAID:1162 ! intestinal secretion xref: BTO:0000644 ! intestinal juice xref: MESH:A12.200.390 ! intestinal secretion intersection_of: UBERON:0000456 ! bodily secretion intersection_of: secreted_by UBERON:0000160 ! intestine xref: UMLS:C0021849 [Term] id: UBERON:0002467 name: filiform papilla def: "The filiform papillae are thin, long 'V'-shaped cones that don't contain taste buds but are the most numerous. These papillae are mechanical and not involved in gustation covering most of the dorsum (upper surface). They are small and arranged in lines parallel to the V-shaped row of circumvallate papillae, except at the tip of the tongue where they are aligned transversely. Projecting from their apices are numerous filamentous processes, or secondary papillae. These are of a whitish tint, owing to the thickness and density of the epithelium of which they are composed. This epithelium has undergone a peculiar modification as the cells have become cornified and elongated into dense, imbricated, brush-like processes. They contain also a number of elastic fibers, which render them firmer and more elastic than the papillae of mucous membrane generally. The larger and longer papillae of this group are sometimes termed papillae conicae. Fungiform papillae are found dispersed throughout the filiform papillae. [WP,unvetted]." [Wikipedia:Filiform_papilla, Wikipedia:Filiform_papilla] subset: uberon_slim synonym: "filiform papillae" EXACT [] synonym: "filiform papillae set" EXACT [] synonym: "filiform papilla of tongue" EXACT [FMA:54820] xref: FMA:54820 ! filiform papilla of tongue xref: MA:0002678 ! filiform papilla xref: ncithesaurus:Filiform_Papilla ! Filiform Papilla xref: NIF_GrossAnatomy:birnlex_4104 ! Filiform papilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Gray1016.png/200px-Gray1016.png xref: EMAPA:18655 ! filiform papillae of epithelium of tongue of pharynx of foregut xref: EMAPA:18873 ! filiform papillae of tongue of pharynx of gut is_a: UBERON:0001726 ! papilla of tongue xref: SCTID:58743008 ! Entire filiform papillae of tongue synonym: "papillae filiformes" RELATED LATIN [Wikipedia:Filiform_papilla] xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1016.png xref: UMLS:C0545782 [Term] id: UBERON:0002468 name: foliate papilla def: "Taste-buds, the end-organs of the gustatory sense, are scattered over the mucous membrane of the mouth and tongue at irregular intervals. They occur especially in the sides of the vallate papillae. There is a localized area at the side of the base of the tongue, the foliate papillae, in which they are especially abundant. [WP,unvetted]." [Wikipedia:Foliate_papilla] subset: uberon_slim synonym: "foliate papillae" EXACT [] synonym: "foliate papillae set" EXACT [] synonym: "foliate papilla of tongue" EXACT [FMA:54823] xref: FMA:54823 ! foliate papilla of tongue xref: MA:0002679 ! foliate papilla xref: ncithesaurus:Foliate_Papilla ! Foliate Papilla xref: NIF_GrossAnatomy:birnlex_4105 ! Foliate papilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Gray1021.png/200px-Gray1021.png is_a: UBERON:0001726 ! papilla of tongue xref: SCTID:362098003 ! Entire foliate papillae of tongue synonym: "papillae foliatae" RELATED LATIN [Wikipedia:Foliate_papilla] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png xref: UMLS:C0545785 [Term] id: UBERON:0004648 name: esophagus muscularis mucosa synonym: "lamina muscularis of esophageal mucous membrane" EXACT [FMA:63059] synonym: "muscularis mucosae of esophagus" EXACT [FMA:63059] synonym: "esophagus muscularis mucosae" EXACT [] xref: FMA:63059 ! Muscularis mucosae of esophagus xref: MA:0002681 ! esophagus muscularis mucosa xref: ncithesaurus:Esophageal_Muscularis_Mucosa ! Esophageal Muscularis Mucosa intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0002469 ! esophagus mucosa xref: SCTID:47720007 ! Lamina muscularis of esophageal mucous membrane def: "A muscularis mucosa that is part of a esophagus." [OBOL:automatic] xref: UMLS:C0227177 [Term] id: UBERON:0002469 name: esophagus mucosa alt_id: UBERON:0003345 def: "A mucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal mucosa" EXACT [] synonym: "esophagus mucosa" EXACT [FMA:62996] synonym: "oesophageal mucosa" EXACT [FMA:62996] synonym: "oesophagus mucosa" EXACT [] synonym: "mucous membrane of esophagus" EXACT [] synonym: "mucous membrane of oesophagus" EXACT [FMA:62996] synonym: "muscularis mucosae of oesophagus" RELATED INCONSISTENT [FMA:62996] synonym: "esophagus mucosa of organ" EXACT [OBOL:automatic] synonym: "esophagus mucous membrane" EXACT [OBOL:automatic] synonym: "esophagus organ mucosa" EXACT [OBOL:automatic] synonym: "gullet mucosa" EXACT [OBOL:automatic] synonym: "gullet mucosa of organ" EXACT [OBOL:automatic] synonym: "gullet mucous membrane" EXACT [OBOL:automatic] synonym: "gullet organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of esophagus" EXACT [OBOL:automatic] synonym: "mucosa of gullet" EXACT [OBOL:automatic] synonym: "mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "mucosa of organ of esophagus" EXACT [OBOL:automatic] synonym: "mucosa of organ of gullet" EXACT [OBOL:automatic] synonym: "mucosa of organ of oesophagus" EXACT [OBOL:automatic] synonym: "mucous membrane of gullet" EXACT [OBOL:automatic] synonym: "oesophagus mucosa of organ" EXACT [OBOL:automatic] synonym: "oesophagus mucous membrane" EXACT [OBOL:automatic] synonym: "oesophagus organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of esophagus" EXACT [OBOL:automatic] synonym: "organ mucosa of gullet" EXACT [OBOL:automatic] synonym: "organ mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "tunica mucosa oesophagi" RELATED [BTO:0002859] xref: FMA:62996 ! Mucosa of esophagus xref: MA:0002680 ! esophagus mucosa xref: EMAPA:26981 ! mucosa of oesophagus of foregut xref: EMAPA:26991 ! mucosa of oesophagus of gut xref: ncithesaurus:Esophageal_Mucosa ! Esophageal Mucosa xref: BTO:0002859 ! esophageal mucosa is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 ! wall of esophagus synonym: "lamina muscularis mucosae oesophageae" EXACT LATIN [FMA:TA, FMA:62996] synonym: "tunica mucosa oesophageae" EXACT LATIN [FMA:TA, FMA:62996] synonym: "tunica mucosa oesophagi" EXACT [] synonym: "tunica mucosa esophagi" EXACT [] xref: SCTID:362127004 ! Entire esophageal mucous membrane xref: UMLS:C0227176 [Term] id: UBERON:0001020 name: commissure def: "White matter fiber bundle that crosses the midline of the brain or spinal cord[NIF]. In the context of Drosophila refers to a broad band of axons connecting the same neuropils each side of the brain[FBbt]." [NIF_GrossAnatomy:nlx_anat_20090513, Wikipedia:Commissure] comment: *not* the same as FMA:76741 Commissure subset: uberon_slim synonym: "commissure of neuraxis" EXACT [FMA:83906] synonym: "neuraxis commissure" EXACT [FMA:83906] xref: FBbt:00005103 ! commissure xref: FMA:83906 ! Commissure of neuraxis xref: OpenCyc:Mx4rdBrmE6gOEdudWQACs5b6Bw xref: ncithesaurus:Commissure ! Commissure xref: OpenCyc:Mx4rdBrmE6gOEdudWQACs5b6Bw ! commissure xref: NIF_GrossAnatomy:nlx_anat_20090513 ! Commissure xref: TADS:0000201 ! adult synganglion commissure is_a: UBERON:0001018 ! axon tract property_value: has_relational_adjective "commissural" xsd:string xref: UMLS:C1185742 [Term] id: UBERON:0005970 name: brain commissure intersection_of: UBERON:0001020 ! commissure intersection_of: part_of UBERON:0000955 ! brain relationship: in_median_plane_of UBERON:0000955 ! brain property_value: external_definition "any of the nerve fiber tracts that span the longitudinal fissure between the cerebral and/or cerebellar hemispheres of the brain[MP]" xsd:string {ontology="MP", external_class="MP:0002199", date_retrieved="2012-08-08"} def: "A commissure that is part of a brain." [OBOL:automatic] [Term] id: UBERON:0007417 ! peduncle of neuraxis name: peduncle of neuraxis synonym: "neuraxis peduncle" EXACT [FMA:83860] xref: FMA:83860 ! peduncle of neuraxis is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002623 name: cerebral peduncle def: "The cerebral peduncle, by most classifications, is everything in the mesencephalon except the tectum. The region includes the midbrain tegmentum, crus cerebri, substantia nigra and pretectum. By this definition, the cerebral peduncles are also known as the basis pedunculi, while the large ventral bundle of efferent fibers is referred to as the crus cerebri or the pes pedunculi There are numerous nerve tracts located within this section of the brainstem. Of note, in the cerebral peduncular loop fibers from motor areas of the brain project to the cerebral peduncle and then project to various thalamic nuclei. In as much as the peduncles are an anatomic landmark, for details regarding the function of this area interested readers are referred to the individual referenced articles. On a broad scale, though, this area contains many nerve tracts conveying motor information to and from the brain to the rest of the body. Important fibers running through the cerebral peduncles include the corticospinal tract and the corticobulbar tract, among others. [WP,unvetted]." [Wikipedia:Cerebral_peduncle] subset: uberon_slim synonym: "cerebral peduncle" EXACT [FMA:62394] synonym: "peduncle of midbrain" EXACT [FMA:62394] xref: FMA:62394 ! Peduncle of midbrain xref: NIF_GrossAnatomy:birnlex_1202 ! Cerebral peduncle xref: ncithesaurus:Cerebral_Peduncle ! Cerebral Peduncle xref: EFO:0001987 ! cerebral peduncle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Gray689.png/200px-Gray689.png xref: BTO:0004676 ! cerebral peduncle xref: BM:CP ! cerebral peduncle is_a: UBERON:0007417 {source="FMA"} ! peduncle of neuraxis relationship: has_part UBERON:0001943 ! midbrain tegmentum relationship: has_part UBERON:0002038 ! substantia nigra synonym: "pedunculus cerebri" EXACT LATIN [FMA:TA, FMA:62394] xref: SCTID:362391000 ! Entire cerebral peduncle synonym: "pedunculus cerebri" RELATED LATIN [Wikipedia:Cerebral_peduncle] xref: http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray689.png xref: UMLS:C0007793 [Term] id: UBERON:0002474 ! cerebellar peduncular complex name: cerebellar peduncular complex def: "A composite structure of the brain stem, which in NeuroNames is subdivided into the superior cerebellar peduncle of pons, the decussation of superior cerebellar peduncle and the superior cerebellar peduncle of midbrain (MM)[NIF]." [Wikipedia:Cerebellar_peduncle, NIF_GrossAnatomy:birnlex_970] comment: todo - this requires work for making consistent with ABA, which strictly separates cerebellum from brainstem. in MA, cerebellar peduncle is part of both brainstem and cerebellar white matter. subset: uberon_slim synonym: "cerebellum peduncles" EXACT [] synonym: "cerebellar peduncles" EXACT [] synonym: "cerebellar peduncles set" EXACT [] synonym: "cerebellar peduncles and decussations" EXACT [NIF_GrossAnatomy:birnlex_970] xref: FMA:77791 ! set of cerebellar peduncles xref: NIF_GrossAnatomy:birnlex_970 ! Cerebellar penducular complex is_a: UBERON:0002317 {source="NIF"} ! white matter of cerebellum synonym: "pedunculi cerebellares" EXACT LATIN [FMA:TA, FMA:77791] xref: ncithesaurus:Cerebellar_Peduncle ! cerebellar peduncle (also: UBERON:0007416 'cerebellar peduncle') synonym: "set of cerebellar peduncles" RELATED [FMA:77791] xref: UMLS:C0228515 [Term] id: UBERON:0007416 ! cerebellar peduncle name: cerebellar peduncle xref: MA:0002742 ! cerebellar peduncle xref: FMA:272298 ! cerebellar peduncle is_a: UBERON:0007417 {source="FMA"} ! peduncle of neuraxis relationship: part_of UBERON:0002474 ! cerebellar peduncular complex xref: SCTID:362417003 ! Entire cerebellar peduncle xref: ncithesaurus:Cerebellar_Peduncle ! cerebellar peduncle (also: UBERON:0002474 'cerebellar peduncular complex') xref: UMLS:C0228515 [Term] id: UBERON:0002152 name: middle cerebellar peduncle def: "The middle cerebellar peduncles (brachia pontis) are composed entirely of centripetal fibers, which arise from the cells of the nuclei pontis of the opposite side and end in the cerebellar cortex; the fibers are arranged in three fasciculi, superior, inferior, and deep. The superior fasciculus, the most superficial, is derived from the upper transverse fibers of the pons; it is directed backward and lateralward superficial to the other two fasciculi, and is distributed mainly to the lobules on the inferior surface of the cerebellar hemisphere and to the parts of the superior surface adjoining the posterior and lateral margins. The inferior fasciculus is formed by the lowest transverse fibers of the pons; it passes under cover of the superior fasciculus and is continued downward and backward more or less parallel with it, to be distributed to the folia on the under surface close to the vermis. The deep fasciculus comprises most of the deep transverse fibers of the pons. It is at first covered by the superior and inferior fasciculi, but crosses obliquely and appears on the medial side of the superior, from which it receives a bundle; its fibers spread out and pass to the upper anterior cerebellar folia. The fibers of this fasciculus cover those of the restiform body. [WP,unvetted]." [Wikipedia:Middle_cerebellar_peduncle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "brachium pontis" EXACT [NIF_GrossAnatomy:birnlex_1529] xref: FMA:72515 ! Middle cerebellar peduncle xref: MA:0002745 ! middle cerebellar peduncle xref: NIF_GrossAnatomy:birnlex_1529 ! Middle cerebellar peduncle xref: NIF_GrossAnatomy:birnlex_1699 xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2b/Gray705.png/200px-Gray705.png xref: BM:Pons-BP ! brachium pontis is_a: UBERON:0007416 ! cerebellar peduncle relationship: part_of UBERON:0002298 ! brainstem relationship: part_of UBERON:0002567 {source="FMA"} ! basal part of pons xref: SCTID:279219000 ! Entire middle cerebellar peduncle synonym: "pedunculus cerebellaris medius" RELATED LATIN [Wikipedia:Middle_cerebellar_peduncle] xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Gray705.png [Term] id: UBERON:0002163 name: inferior cerebellar peduncle def: "The upper part of the posterior district of the medulla oblongata is occupied by the inferior peduncle, a thick rope-like strand situated between the lower part of the fourth ventricle and the roots of the glossopharyngeal and vagus nerves. Each cerebellar inferior peduncle connects the medulla spinalis and medulla oblongata with the cerebellum, and comprises the juxtarestiform body and restiform body. Important fibers running through the inferior cerebellar peduncle include the spinocerebellar tract and axons from the inferior olivary nucleus, among others. [WP,unvetted]." [Wikipedia:Inferior_cerebellar_peduncle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "restiform body" EXACT [NIF_GrossAnatomy:birnlex_1691] synonym: "inferior peduncle" RELATED [Wikipedia:Inferior_cerebellar_peduncle] xref: FMA:72615 ! Inferior cerebellar peduncle xref: MA:0002744 ! inferior cerebellar peduncle xref: NIF_GrossAnatomy:birnlex_1645 xref: NIF_GrossAnatomy:birnlex_1691 ! Inferior cerebellar peduncle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fc/Gray677.png/200px-Gray677.png xref: BM:RB ! restiform body is_a: UBERON:0007416 ! cerebellar peduncle relationship: part_of UBERON:0001896 {source="FMA"} ! medulla oblongata synonym: "corpus restiforme" EXACT LATIN [FMA:TA, FMA:72615] xref: SCTID:362418008 ! Entire inferior cerebellar peduncle synonym: "pedunculus cerebellaris inferior" RELATED LATIN [Wikipedia:Inferior_cerebellar_peduncle] xref: http://upload.wikimedia.org/wikipedia/commons/f/fc/Gray677.png [Term] id: UBERON:0002150 ! superior cerebellar peduncle name: superior cerebellar peduncle def: "The superior cerebellar peduncles (brachium conjunctivum), two in number, emerge from the upper and medial part of the white substance of the hemispheres and are placed under cover of the upper part of the cerebellum. They are joined to each other across the middle line by the anterior medullary velum, and can be followed upward as far as the inferior colliculi, under which they disappear. Below, they form the upper lateral boundaries of the fourth ventricle, but as they ascend they converge on the dorsal aspect of the ventricle and thus assist in roofing it in. All fibers (except vestibular fibers to the vestibular nuclei through the inferior cerebellar peduncle) carrying information from the cerebellum to the midbrain and pons pass through the superior cerebellar peduncle. [WP,unvetted]." [Wikipedia:Superior_cerebellar_peduncle] comment: Editor notes: we follow NIF in dividing this into 3 parts. This allows for consistency with ABA. AO notes: we make the TAO class disjoint for now as it's not clear if this is the analagous structure subset: uberon_slim synonym: "brachium conjunctivum" EXACT [NIF_GrossAnatomy:birnlex_1711] synonym: "superior peduncle" RELATED [Wikipedia:Superior_cerebellar_peduncle] xref: MA:0002746 ! superior cerebellar peduncle xref: NIF_GrossAnatomy:birnlex_1711 ! Superior cerebellar peduncle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Gray704.png/200px-Gray704.png xref: BM:BC ! brachium conjunctivum is_a: UBERON:0007416 ! cerebellar peduncle xref: SCTID:279218008 ! Entire superior cerebellar peduncle synonym: "pedunculus cerebellaris superior" RELATED LATIN [Wikipedia:Superior_cerebellar_peduncle] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Gray704.png [Term] id: UBERON:0007707 name: superior cerebellar peduncle of midbrain def: "Regional part of superior cerebellar peduncle, located in the midbrain, consisting of a large bundle of fibers largely projecting from the deep cerebellar nuclei to the midbrain and thalamus. It is continuous with the superior cerebellar peduncle of the pons. (MM)." [NIF_GrossAnatomy:birnlex_1162] synonym: "SCPMB" EXACT [NIF_GrossAnatomy:birnlex_1162] synonym: "superior cerebellar peduncle of midbrain" EXACT [NIF_GrossAnatomy:birnlex_1162] xref: NIF_GrossAnatomy:birnlex_1162 ! Superior cerebellar peduncle of midbrain is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002150 ! superior cerebellar peduncle relationship: part_of UBERON:0001943 {source="NIF"} ! midbrain tegmentum [Term] id: UBERON:0007709 name: superior cerebellar peduncle of pons comment: note that FMA:72495 most likely denotes this class rather than the more generic parent, due to the part of relationship to pontine tegmentum. synonym: "SCPP" EXACT [NIF_GrossAnatomy:birnlex_1726] synonym: "superior cerebellar peduncle of pons" EXACT [NIF_GrossAnatomy:birnlex_1726] xref: NeuroNames:1007150190 xref: NIF_GrossAnatomy:birnlex_1726 ! Superior cerebellar peduncle of pons xref: FMA:72495 ! Superior cerebellar peduncle is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002150 ! superior cerebellar peduncle relationship: part_of UBERON:0003023 ! pontine tegmentum relationship: part_of UBERON:0003023 {source="FMA"} ! pontine tegmentum [Term] id: UBERON:0002588 name: decussation of superior cerebellar peduncle alt_id: UBERON:0003032 def: "Regional part of superior cerebellar peduncle located in the caudal midbrain, at the level of the inferior colliculus, consisting of a large bundle of fibers crossing the midline. It contains fibers projecting from the deep cerebellar nucleus to the midbrain and thalamus through the superior cerebellar peduncle (MM). The decussation of superior cerebellar peduncle is the portion of the superior cerebellar peduncle which crosses into the midbrain. [WP,unvetted]." [Wikipedia:Decussation_of_superior_cerebellar_peduncle, NIF_GrossAnatomy:birnlex_1089] subset: uberon_slim synonym: "decussation of brachium conjunctivum" EXACT [FMA:72455] synonym: "decussation of superior cerebellar peduncles" EXACT [FMA:72455] synonym: "superior cerebellar peduncle decussation" EXACT [FMA:72455] synonym: "Wernekink's decussation" EXACT [FMA:72455] xref: FMA:72455 ! Decussation of superior cerebellar peduncle xref: NIF_GrossAnatomy:birnlex_1089 ! Decussation of superior cerebellar peduncle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/26/Gray711.png/200px-Gray711.png xref: BM:BCX ! decussation of brachium conjunctivum is_a: UBERON:0007418 ! decussation of neuraxis relationship: part_of UBERON:0001943 {source="FMA"} ! midbrain tegmentum relationship: part_of UBERON:0002150 ! superior cerebellar peduncle synonym: "decussatio pedunculorum cerebellarium superiorum" EXACT LATIN [FMA:TA, FMA:72455] xref: SCTID:369252009 ! Entire decussation of superior cerebellar peduncles [Term] id: UBERON:0002475 name: saphenous nerve def: "The saphenous nerve (long or internal saphenous nerve) is the largest cutaneous branch of the femoral nerve. [WP,unvetted]." [Wikipedia:Saphenous_nerve] subset: uberon_slim xref: FMA:45262 ! Saphenous nerve xref: MA:0002761 ! saphenous nerve xref: OpenCyc:Mx4rvY0kgpwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rvY0kgpwpEbGdrcN5Y29ycA ! saphenous nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/de/Gray827.png/200px-Gray827.png is_a: UBERON:0002003 ! peripheral nerve relationship: branch_of UBERON:0001267 ! femoral nerve xref: SCTID:181079005 ! Entire saphenous nerve synonym: "nervus saphenus" RELATED LATIN [Wikipedia:Saphenous_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/de/Gray827.png [Term] id: UBERON:0002476 name: lateral globus pallidus def: "The lateral globus pallidus (or external, GPe) receives a strong glutamatergic projection from the subthalamic nucleus. The two form a particular system: a coupled pacemaker. The axons of the external globus pallidum go essentially to the subthalamic nucleus. They go also to other elements of the basal ganglia system, the striatum, the substantia nigra pars reticulata, and the internal globus pallidus, where they release the neurotransmitter GABA. GPe is particular in comparison to the other elements of the set by the fact that it does not work as an output base of the basal ganglia (not sending axons to the thalamus) but as the main regulator of the basal ganglia system. It is sometimes used as a target for deep brain stimulation as a treatment for Parkinson's disease. [WP,unvetted]." [Wikipedia:Lateral_globus_pallidus] subset: uberon_slim synonym: "external globus pallidus" EXACT [] synonym: "globus pallidus external segment" EXACT [MA:0002767, FMA:61839, NIF_GrossAnatomy:birnlex_1610] synonym: "globus pallidus externus" EXACT [] synonym: "globus pallidus lateral segment" RELATED [MA:0002767] synonym: "globus pallidus, lateral segment" EXACT [] synonym: "lateral pallidal segment" EXACT [] synonym: "lateral part of globus pallidus" EXACT [] synonym: "pallidus II" EXACT [FMA:61839] synonym: "globus pallidus lateralis" EXACT [BTO:0002247] synonym: "external pallidum" EXACT [NIF_GrossAnatomy:birnlex_1610] synonym: "external part of globus pallidus" EXACT [NIF_GrossAnatomy:birnlex_1610] synonym: "lateral pallidum" EXACT [NIF_GrossAnatomy:birnlex_1610] synonym: "lateral segment of globus pallidus" EXACT [NIF_GrossAnatomy:birnlex_1610] synonym: "pallidum I" RELATED [BTO:0002247] xref: FMA:61839 ! Lateral globus pallidus xref: MA:0002767 ! lateral globus pallidus xref: BTO:0002247 ! globus pallidus lateralis xref: NIF_GrossAnatomy:birnlex_1610 ! Globus pallidus external segment xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Brain_structure.gif/200px-Brain_structure.gif xref: ABA:GPe ! Globus pallidus, external segment is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001875 ! globus pallidus relationship: spatially_disjoint_from UBERON:0002477 {source="ABA"} ! medial globus pallidus synonym: "pars lateralis globi pallidi medialis" EXACT LATIN [FMA:TA, FMA:61839] xref: SCTID:361560008 ! Entire lateral globus pallidus xref: EHDAA2:0004462 ! globus pallidus externus xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Brain_structure.gif [Term] id: UBERON:0000432 name: endopeduncular nucleus def: "A portion of the nucleus of ansa lenticularis located medial to the posterior limb of the internal capsule, along the course of the ansa lenticularis and the inferior thalamic peduncle or as a separate nucleus within the internal capsule adjacent to the medial GLOBUS PALLIDUS (NeuroNames, http://rprcsgi.rprc. washington.edu/neuronames/ (September 28, 1998)). In non-primates, the entopeduncular nucleus is analogous to both the medial globus pallidus and the entopeduncular nucleus of human." [MESH:A08.186.211.730.385.800.240] comment: The term entopeduncular nucleus in human neuroanatomy refers to a portion of the nucleus of the ansa lenticularis described variously as located medial to the posterior limb of the internal capsule ( Riley-1943 ), along the course of the ansa lenticularis and the inferior thalamic peduncle ( Crosby-1962 ), or as a separate nucleus within the internal capsule adjacent to the medial segment of the globus pallidus ( Nomina-1983 ).[NN] synonym: "nucleus endopeduncularis" RELATED [BTO:0002475] synonym: "nucleus entopeduncularis" RELATED [] synonym: "entopeduncular nucleus" RELATED [] xref: BTO:0002475 xref: FMA:77691 ! Endopeduncular nucleus xref: MESH:A08.186.211.730.385.800.240 ! entopeduncular nucleu is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0009641 {source="NN"} ! ansa lenticularis xref: SCTID:82705008 ! Entire endopeduncular nucleus [Term] id: UBERON:0002477 name: medial globus pallidus def: "The medial globus pallidus (or internal, GPi) is one of the output nuclei of the basal ganglia. The GABA-containing neurons send their axons to specific nuclei of the dorsal thalamus (VA and VL), to the centromedian complex and to the pedunculopontine complex. The efferent bundle is constituted first of the ansa and fasciculus lenticularis, then crosses the internal capsule as the Edinger's comb system then arrives at the laterosuperior corner of the subthalamic nucleus and constitutes the Forel's field H2, then H, and suddenly changes its direction to form H1 that goes to the inferior part of the thalamus. The distribution of axonal islands is widespread in the lateral region of the thalamus. The innervation of the central region is done by collaterals. [WP,unvetted]." [Wikipedia:Medial_globus_pallidus] comment: See also: endopeduncular nucleus subset: uberon_slim synonym: "entopeduncular nucleus (monakow)" EXACT [FMA:61840] synonym: "globus pallidus internal segment" EXACT [FMA:61840] synonym: "globus pallidus internus" EXACT [FMA:61840] synonym: "globus pallidus medial segment" EXACT [FMA:61840] synonym: "globus pallidus medialis" EXACT [FMA:TA] synonym: "globus pallidus, medial segment" EXACT [FMA:61840] synonym: "internal globus pallidus" EXACT [FMA:61840] synonym: "medial pallidal segment" EXACT [FMA:61840] synonym: "medial part of globus pallidus" EXACT [FMA:61840] synonym: "mesial pallidum" EXACT [FMA:61840] synonym: "pallidus I" EXACT [FMA:61840] synonym: "globus pallidus interna" EXACT LATIN [] synonym: "globus pallidus internus" EXACT LATIN [] synonym: "globus pallidus medialis" EXACT LATIN [] synonym: "entopeduncular nucleus" RELATED [MA:0002768] synonym: "entopeduncular nucleus (monakow)" EXACT [] synonym: "globus pallidus inernal segment" RELATED [MA:0002768] synonym: "globus pallidus internal segment" EXACT [] synonym: "globus pallidus internus" EXACT [] synonym: "globus pallidus medial segment" RELATED [MA:0002768] synonym: "globus pallidus, medial segment" EXACT [] synonym: "internal globus pallidus" EXACT [] synonym: "medial pallidal segment" EXACT [] synonym: "medial part of globus pallidus" EXACT [] synonym: "mesial pallidum" EXACT [] synonym: "globus pallidus medialis" EXACT [BTO:0002248] synonym: "internal pallidum" EXACT [NIF_GrossAnatomy:birnlex_1555] synonym: "internal part of globus pallidus" EXACT [NIF_GrossAnatomy:birnlex_1555] synonym: "medial segment of globus pallidus" EXACT [NIF_GrossAnatomy:birnlex_1555] synonym: "pallidum I" RELATED [] synonym: "pallidus I" RELATED [] synonym: "pars medialis globi pallidi" EXACT LATIN [FMA:TA, FMA:61840] xref: FMA:61840 ! Medial globus pallidus xref: MA:0002768 ! medial globus pallidus xref: BTO:0002248 ! globus pallidus medialis xref: NIF_GrossAnatomy:birnlex_1555 ! Globus pallidus internal segment xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ee/Brain_structure.gif/200px-Brain_structure.gif xref: ABA:GPi ! Globus pallidus, internal segment is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001875 {source="MA"} ! globus pallidus relationship: spatially_disjoint_from UBERON:0002476 {source="ABA"} ! lateral globus pallidus xref: SCTID:361562000 ! Entire medial globus pallidus xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Brain_structure.gif [Term] id: UBERON:0002479 name: dorsal lateral geniculate nucleus def: "The main division of the lateral geniculate body; consists of two magnocellular layers [TA] (strata magnocellularia [TA]) and four parvocellular layers [TA] (strata parvocellularia [TA]) and serves as a processing station in the major pathway from the retina to the cerebral cortex, receiving fibers from the optic tract and giving rise to the geniculocalcarine radiation to the visual cortex in the occipital lobe." [http://www.medilexicon.com/medicaldictionary.php?t=61422] synonym: "dorsal nucleus of lateral geniculate body" RELATED [MA:0002775] synonym: "lateral geniculate complex, dorsal part" EXACT [] synonym: "nucleus geniculatus lateralis pars dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1595] synonym: "nucleus dorsalis corporis geniculati lateralis" EXACT LATIN [FMA:TA, FMA:62214] xref: FMA:62214 ! Dorsal nucleus of lateral geniculate body xref: MA:0002775 ! dorsal lateral geniculate nucleus xref: NIF_GrossAnatomy:birnlex_1595 ! Dorsal nucleus of lateral geniculate body xref: ABA:LGd ! Dorsal part of the lateral geniculate complex xref: BM:GLd ! dorsal lateral geniculate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001926 ! lateral geniculate body relationship: spatially_disjoint_from UBERON:0001927 {source="ABA"} ! medial geniculate body [Term] id: UBERON:0002480 name: ventral lateral geniculate nucleus synonym: "lateral geniculate complex, ventral part" EXACT [] synonym: "pregeniculate nucleus" EXACT [] synonym: "ventral nucleus of lateral geniculate body" RELATED [MA:0002776] synonym: "dorsal_nucleus_of_lateral_geniculate_body" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "corpus geniculatum externum, nucleus accessorius" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "corpus geniculatum laterale, pars oralis" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "griseum praegeniculatum" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "lateral geniculate complex, ventral part (kolliker)" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "lateral geniculate nucleus, ventral part" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "nucleus corporis geniculati lateralis, pars ventralis" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "nucleus praegeniculatus" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "nucleus pregeniculatum" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "praegeniculatum" EXACT [NIF_GrossAnatomy:birnlex_1597] synonym: "ventral part of the lateral geniculate complex" EXACT [NIF_GrossAnatomy:birnlex_1597] xref: FMA:62215 ! Ventral nucleus of lateral geniculate body xref: MA:0002776 ! ventral lateral geniculate nucleus xref: NIF_GrossAnatomy:birnlex_1597 ! Ventral nucleus of lateral geniculate body xref: ABA:LGv ! Ventral part of the lateral geniculate complex xref: BM:LGv ! ventral lateral geniculate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001926 ! lateral geniculate body synonym: "nucleus pregeniculatus" EXACT LATIN [FMA:TA, FMA:62215] synonym: "nucleus ventralis corporis geniculati lateralis" EXACT LATIN [FMA:TA, FMA:62215] [Term] id: UBERON:0013605 name: layer of lateral geniculate body is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001926 ! lateral geniculate body xref: FMA:76988 ! Koniocellular layer of dorsal nucleus of lateral geniculate body [Term] id: UBERON:0013615 name: koniocellular layer of dorsal nucleus of lateral geniculate body comment: Short-wavelength "blue" cones.[WP] synonym: "konioocellular layer of lateral geniculate nucleus" EXACT [] is_a: UBERON:0013605 ! layer of lateral geniculate body relationship: part_of UBERON:0002479 ! dorsal lateral geniculate nucleus xref: FMA:76988 ! Koniocellular layer of dorsal nucleus of lateral geniculate body [Term] id: UBERON:0013606 name: magnocellular layer of dorsal nucleus of lateral geniculate body comment: Rods; necessary for the perception of movement, depth, and small differences in brightness[WP] synonym: "magnocellular layer of lateral geniculate nucleus" EXACT [] synonym: "lateral geniculate nucleus magnocellular layer " EXACT [] synonym: "strata magnocellularia " BROAD [] intersection_of: UBERON:0013605 ! layer of lateral geniculate body intersection_of: composed_primarily_of CL:0011003 ! magnocellular neurosecretory cell relationship: part_of UBERON:0002479 ! dorsal lateral geniculate nucleus xref: FMA:76989 ! Magnocellular layer of dorsal nucleus of lateral geniculate body [Term] id: UBERON:0013607 name: parvocellular layer of dorsal nucleus of lateral geniculate body comment: Cones; long- and medium-wavelength ("red" and "green" cones); necessary for the perception of color and form (fine details).[WP] synonym: "parvocellular layer of lateral geniculate nucleus" EXACT [] synonym: "strata parvocellularia " BROAD [] intersection_of: UBERON:0013605 ! layer of lateral geniculate body intersection_of: composed_primarily_of CL:1001505 ! parvocellular neurosecretory cell relationship: part_of UBERON:0002479 ! dorsal lateral geniculate nucleus xref: FMA:76992 ! Parvocellular layer of dorsal nucleus of lateral geniculate body [Term] id: UBERON:0004755 ! skeletal tissue name: skeletal tissue def: "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]" [VSAO:0000015, GO_REF:0000034, PSPUB:0000170] comment: Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from synonym: "mineralized tissue" NARROW [] xref: VSAO:0000015 ! skeletal tissue is_a: UBERON:0002384 {source="VSAO"} ! connective tissue relationship: part_of UBERON:0004765 ! skeletal element relationship: develops_from CL:0007001 {source="VSAO", external_class="VSAO:0000015", date_retrieved="2012-08-14"} ! skeletogenic cell disjoint_from: UBERON:0003714 ! neural tissue xref: SCTID:309311006 ! Skeletal tissue xref: XAO:0004038 ! skeletal tissue xref: ZFA:0005619 ! skeletal tissue property_value: external_definition "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000015", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170", notes="taken from version of VSAO used in TAO and used directly in Uberon"} [Term] id: UBERON:0002481 name: bone tissue def: "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts[VSAO]." [Wikipedia:Bone_tissue, VSAO:0000047] subset: uberon_slim synonym: "osseous tissue" EXACT [] synonym: "calcium tissue" EXACT [] synonym: "osteogenic tissue" EXACT [VSAO:curator] xref: FMA:224804 ! Bone tissue xref: galen:BoneTissue xref: MA:0002780 ! bone tissue xref: MESH:A02.835.232 ! bone xref: ncithesaurus:Bone_Tissue ! Bone Tissue xref: VSAO:0000047 ! bone tissue xref: ZFA:0005621 ! bone tissue is_a: UBERON:0004755 {source="VSAO"} ! skeletal tissue relationship: part_of UBERON:0001474 ! bone element relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: has_part CHEBI:52255 ! hydroxylapatite property_value: external_definition "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000047", date_retrieved="2012-08-14", source="GO_REF:0000034", source="PSPUB:0000170"} xref: UMLS:C0391978 [Term] id: UBERON:0002482 name: lamellar bone def: "Bone tissue that has a regular parallel alignment of collagen into sheets (lamellae) and is mechanically strong." [Wikipedia:Bone#Woven_or_lamellar] comment: histological classification, lamellar vs woven. Note that only FMA has woven xref: FMA:224806 ! Lamellar bone xref: galen:LamellarBone xref: MA:0002781 ! lamellar bone is_a: UBERON:0002481 ! bone tissue [Term] id: UBERON:0002484 name: bone marrow cavity def: "the central cavity of bone shafts where red bone marrow and/or yellow bone marrow (adipose tissue) is stored; hence, the medullary cavity is also known as the marrow cavity. Located in the main shaft (cortical bone) of a long bone (diaphysis) (consisting mostly of compact bone), the medullary cavity has walls composed of spongy bone (cancellous bone) and is lined with a thin, vascular membrane (endosteum)" [Wikipedia:Bone_marrow_of_ovaryry_cavity] comment: AO notes: not clear if the FMA intends to have two classes. MP:0000065: "the medullary cavities of the bones.". NCITA also has "medullary bone" synonym: "marrow cavity" EXACT [FMA:83698] synonym: "cavity of cancellous bone" EXACT [] synonym: "medullary cavity" EXACT [FMA:83698] xref: FMA:75147 ! Bone marrow cavity xref: FMA:83698 ! medullary cavity xref: MA:0002783 ! bone marrow cavity is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001439 ! compact bone relationship: surrounds UBERON:0002371 ! bone marrow relationship: dubious_for_taxon NCBITaxon:7955 {source="doi:10.1177/0192623311409597"} ! Danio rerio [Term] id: UBERON:0002486 name: glottis def: "The glottis is defined as the combination of the vocal folds and the space in between the folds. [WP,unvetted]." [Wikipedia:Glottis] subset: uberon_slim xref: FMA:55414 ! Glottis xref: MA:0002788 ! glottis xref: ncithesaurus:Glottis ! Glottis xref: BTO:0001627 ! glottis xref: GAID:343 ! glottis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/32/Arytenoid_cartilage.png/200px-Arytenoid_cartilage.png xref: MESH:A04.329.364 ! glottis is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001737 ! larynx xref: AAO:0010610 ! glottis xref: SCTID:264482000 ! Entire glottis xref: http://upload.wikimedia.org/wikipedia/commons/3/32/Arytenoid_cartilage.png property_value: external_definition "A small, slit-like aperture lying longitudinally on the floor of the pharynx.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010610", date_retrieved="2012-06-20", source="AAO:BMZ"} xref: UMLS:C0017681 [Term] id: UBERON:0002487 name: tooth cavity def: "." [Wikipedia:Tooth_cavity] subset: uberon_slim synonym: "cavitas dentis" EXACT [] synonym: "cavity of tooth" RELATED [MA:0002792] synonym: "pulp cavity" EXACT [] synonym: "pulp cavity of tooth" EXACT [] synonym: "tooth pulp cavity" RELATED [MA:0002792] xref: FMA:55660 ! Cavity of tooth xref: MA:0002792 ! tooth cavity xref: MESH:A14.254.900.265 ! dental pulp cavity is_a: UBERON:0002558 ! organ cavity relationship: part_of UBERON:0001091 ! tooth synonym: "cavitas pulparis" EXACT LATIN [FMA:TA, FMA:55660] xref: SCTID:362105008 ! Entire cavity of tooth [Term] id: UBERON:0002488 name: helix def: "." [Wikipedia:Helix] subset: uberon_slim synonym: "helical part of pinna" EXACT [] synonym: "helix (auricula)" EXACT [] synonym: "helix of auricle of ear" EXACT [] synonym: "helix of ear" EXACT [] synonym: "helix of pinna" EXACT [] xref: FMA:60992 ! Helix xref: MA:0002793 ! helix xref: ncithesaurus:Helix ! Helix xref: OpenCyc:Mx4rwRDEk5wpEbGdrcN5Y29ycA ! helix is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001757 ! pinna xref: SCTID:279607004 ! Entire helix of ear xref: UMLS:C0229304 [Term] id: UBERON:0010361 name: synostosis def: "Nonsynovial joint in which the articulating bones are connected by bone. Examples: epiphyseal junction, manubriosternal synostosis." [FMA:7499] synonym: "bony union" EXACT [FMA:7499] synonym: "junctura ossea" EXACT LATIN [FMA:TA] is_a: UBERON:0011134 {source="FMA"} ! nonsynovial joint xref: ZFA:0005610 ! synostosis xref: FMA:7499 ! synostosis xref: SCTID:1216008 ! Synostosis [Term] id: UBERON:0011161 name: spheno-occipital synchondrosis def: "the cartilaginous junction between the basisphenoid and basioccipital bones of the mammalian skull that in humans is usually closed by the age of 25" [http://www.merriam-webster.com/medical/spheno-occipital%20synchondrosis] intersection_of: UBERON:0001725 ! cranial synchondrosis intersection_of: connects UBERON:0006428 ! basisphenoid bone intersection_of: connects UBERON:0001692 ! basioccipital bone xref: FMA:54818 ! spheno-occipital synchondrosis xref: SCTID:140895003 ! Entire sphenooccipital synchondrosis [Term] id: UBERON:0000969 ! joint connecting hardened body parts name: obsolete joint connecting hardened body parts is_obsolete: true [Term] id: UBERON:0009198 ! craniofacial suture name: craniofacial suture comment: Editor notes: we follow GO in dividing sutures into cranial and facial and making a grouping class, but this is not consistent with FMA def: "any suture between cranial and/or facial bones." [GO:0097094] synonym: "joint of the skull bones" EXACT [OBOL:automatic] synonym: "articulation of skull bones" RELATED [OBOL:automatic] is_a: UBERON:0002209 {source="FMA-abduced"} ! fibrous joint [Term] id: UBERON:0003685 name: cranial suture def: "Fibrous joint in which the articulating bones or cartilages of the skull are connected by sutural ligaments (scant amount of collagenous dense connective tissue). Examples: sagittal suture, frontal suture." [ISBN:3110148986, Wikipedia:Suture_(joint), FMA:71385] subset: uberon_slim synonym: "sutura" EXACT [] synonym: "suture" EXACT [FMA:71385] synonym: "suture joint of skull" EXACT [SCTID:244509003] synonym: "cranium suture" EXACT [OBOL:automatic] synonym: "suture of cranium" EXACT [OBOL:automatic] xref: GAID:211 ! cranial suture xref: MA:0001475 ! cranial suture xref: FMA:7493 ! Suture xref: MESH:A02.835.232.781.200 ! cranial suture is_a: UBERON:0009198 {source="GO"} ! craniofacial suture intersection_of: UBERON:0002209 ! fibrous joint intersection_of: part_of UBERON:0003128 ! cranium relationship: induced_by UBERON:0002363 {source="PMID:16496288"} ! dura mater xref: SCTID:244509003 ! Entire suture joint of skull [Term] id: UBERON:0009199 ! facial suture name: facial suture def: "any suture between facial bones." [GO:0097096] is_a: UBERON:0009198 ! craniofacial suture intersection_of: UBERON:0009198 ! craniofacial suture intersection_of: connects UBERON:0003462 {cardinality="2"} ! facial bone relationship: connects UBERON:0003462 {notes="between two adjacent facial bones"} ! facial bone [Term] id: UBERON:0011160 ! nasal suture name: nasal suture def: "a suture joining a nasal bone to another bone." [] intersection_of: UBERON:0009199 ! facial suture intersection_of: connects UBERON:0001681 ! nasal bone xref: SCTID:368992007 ! Entire nasal suture of skull [Term] id: UBERON:0009203 name: internasal suture def: "a suture joining the nasal bones." [Wikipedia:Internasal_suture] synonym: "internasal suture of skull" EXACT [FMA:52959] synonym: "inter-nasal suture" EXACT [] synonym: "sutura internasalis" EXACT [Wikipedia:Internasal_suture] synonym: "nasal suture" BROAD [GO:0097097] is_a: UBERON:0011160 ! nasal suture intersection_of: UBERON:0009199 ! facial suture intersection_of: connects UBERON:0001681 {cardinality="2"} ! nasal bone relationship: connects UBERON:0001681 {notes="between both nasal bones"} ! nasal bone xref: FMA:52959 ! internasal suture xref: SCTID:368990004 ! Entire internasal suture of skull synonym: "sutura internasalis" RELATED LATIN [Wikipedia:Internasal_suture] [Term] id: UBERON:0005404 name: frontonasal suture def: "A suture between frontal and nasal bones" [GO:0097095, PMID:12416537] synonym: "frontonasal suture of skull" EXACT [FMA:52948] synonym: "articulation of the nasal bone with frontal bone" RELATED [] xref: FMA:52948 ! Frontonasal suture xref: MA:0002973 ! frontonasal suture intersection_of: UBERON:0009198 ! craniofacial suture intersection_of: connects UBERON:0001681 ! nasal bone intersection_of: connects UBERON:0000209 ! tetrapod frontal bone xref: SCTID:368982004 ! Entire frontonasal suture of skull [Term] id: UBERON:0002489 name: coronal suture def: "The coronal suture is a dense, fibrous connective tissue joint that separates the frontal and parietal bones of the skull. At birth, the bones of the skull do not meet. [WP,unvetted]." [Wikipedia:Coronal_suture] subset: uberon_slim synonym: "coronal suture of skull" EXACT [] synonym: "fronto-parietal suture" EXACT [PMID:11784098] synonym: "frontoparietal suture" EXACT [PMID:11784098] xref: FMA:52928 ! Coronal suture xref: MA:0002795 ! coronal suture xref: OpenCyc:Mx4rv2eGHZwpEbGdrcN5Y29ycA xref: OpenCyc:Mx4rv2eGHZwpEbGdrcN5Y29ycA ! coronal suture xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ae/Gray188-Coronal_suture.png/200px-Gray188-Coronal_suture.png xref: EMAPA:19225 ! coronal suture is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0000209 ! tetrapod frontal bone intersection_of: connects UBERON:0000210 ! tetrapod parietal bone relationship: part_of UBERON:0004339 ! vault of skull xref: SCTID:244510008 ! Entire coronal suture of skull synonym: "sutura coronalis" RELATED LATIN [Wikipedia:Coronal_suture] xref: http://upload.wikimedia.org/wikipedia/commons/a/ae/Gray188-Coronal_suture.png [Term] id: UBERON:0002490 name: frontal suture def: "The frontal suture is a dense connective tissue structure that divides the two halves of the frontal bone of the skull in infants and children. It usually disappears by the age of six, with the two halves of the frontal bone being fused together. If it does not disappear it may be called a 'metopic suture' or 'sutura frontalis persistens. ' If the suture is not present at birth (craniosynostosis) it will cause a keel-shaped deformity of the skull called 'trigonocephaly. ' It is present in a fetal skull so that the skull can bend and is very elastic at the time of birth. The baby's head literally bends when coming out of the mother's womb. The space is filled as the child grows older. [WP,unvetted]." [Wikipedia:Frontal_suture] subset: uberon_slim synonym: "frontal suture of skull" EXACT [] synonym: "metopic suture" RELATED [MA:0002796] synonym: "sutura frontalis" EXACT [Wikipedia:Frontal_suture] xref: FMA:52989 ! Frontal suture xref: MA:0002796 ! frontal suture xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/17/Gray134.png/200px-Gray134.png xref: EMAPA:19226 ! metopic suture is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0000209 {cardinality="2"} ! tetrapod frontal bone relationship: connects UBERON:0000209 {notes="two halves of the frontal bone"} ! tetrapod frontal bone synonym: "sutura metopica" EXACT LATIN [FMA:TA, FMA:52989] xref: SCTID:136854008 ! Entire frontal suture of skull synonym: "sutura frontalis" RELATED LATIN [Wikipedia:Frontal_suture] xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Frontal_suture.png [Term] id: UBERON:0002491 name: lambdoid suture def: "The lambdoid suture (or lambdoidal suture) is a dense, fibrous connective tissue joint on the posterior aspect of the skull that connects the parietal and temporal bones with the occipital bone. Its name comes from its lambda-like shape. [WP,unvetted]." [Wikipedia:Lambdoid_suture] subset: uberon_slim synonym: "lambdoid suture of skull" EXACT [] synonym: "lambdoidal suture" RELATED [MA:0002797] synonym: "sutura lambdoidea" RELATED [Wikipedia:Lambdoid_suture] xref: FMA:52933 ! Lambdoid suture xref: MA:0002797 ! lambdoid suture xref: EMAPA:19227 ! lambdoidal suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0001678 ! temporal bone intersection_of: connects UBERON:0000210 ! tetrapod parietal bone intersection_of: connects UBERON:0001676 ! occipital bone relationship: part_of UBERON:0004339 {source="HP"} ! vault of skull relationship: part_of UBERON:0001703 ! neurocranium xref: SCTID:361830007 ! Entire lambdoid suture of skull synonym: "sutura lambdoidea" RELATED LATIN [Wikipedia:Lambdoid_suture] xref: http://upload.wikimedia.org/wikipedia/commons/3/3d/Gray188-Lambdoid_suture.png [Term] id: UBERON:0002492 name: sagittal suture def: "The sagittal suture is a dense, fibrous connective tissue joint between the two parietal bones of the skull. At birth, the bones of the skull do not meet. If certain bones of the skull grow too fast then 'premature closure' of the sutures may occur. This can result in skull deformities. If the sagittal suture closes early the skull becomes long, narrow, and wedge-shaped, a condition called 'scaphocephaly. ' Two anatomical landmarks are found on the sagittal suture: the bregma and the vertex of the skull. The bregma is formed by the intersection of the sagittal and coronal sutures, and the vertex is the highest point on the skull and is many times near the midpoint of the sagittal suture. The sagittal suture is also known as the 'interparietal suture' and the 'sutura interparietalis. ' The term is derived from the Latin word Sagitta, meaning 'arrow'. The derivation of this term may be demonstrated by observing how the sagittal suture is notched posteriorly, like an arrow, by the lambdoid suture. [WP,unvetted]." [Wikipedia:Sagittal_suture] subset: uberon_slim synonym: "sagittal suture of skull" EXACT [] xref: FMA:52929 ! Sagittal suture xref: MA:0002798 ! sagittal suture xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/24/Kort-lang-skalle.gif/200px-Kort-lang-skalle.gif xref: EMAPA:19224 ! sagittal suture is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0000210 {cardinality="2"} ! tetrapod parietal bone relationship: connects UBERON:0000210 {notes="both parietals"} ! tetrapod parietal bone relationship: part_of UBERON:0004339 ! vault of skull xref: SCTID:244511007 ! Entire sagittal suture of skull synonym: "sutura sagittalis" RELATED LATIN [Wikipedia:Sagittal_suture] xref: http://upload.wikimedia.org/wikipedia/commons/2/24/Kort-lang-skalle.gif [Term] id: UBERON:0002493 name: uterine artery def: "The uterine artery is an artery in females that supplies blood to the uterus. [WP,unvetted]." [Wikipedia:Uterine_artery] subset: uberon_slim xref: FMA:18829 ! Uterine artery xref: MA:0002799 ! uterine artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ae/Gray1170.png/200px-Gray1170.png is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0000995 ! uterus xref: SCTID:244300003 ! Entire uterine artery synonym: "arteria uterina" RELATED LATIN [Wikipedia:Uterine_artery] xref: http://upload.wikimedia.org/wikipedia/commons/a/ae/Gray1170.png relationship: in_lateral_side_of UBERON:0000995 {source="FMA-abduced-lr"} ! uterus [Term] id: UBERON:0002494 name: papillary muscle def: "In anatomy, the papillary muscles of the heart serve to limit the movements of the mitral and tricuspid valves. These muscles contract to tighten the chordae tendineae, which in turn prevent inversion. This occurs in response to pressure gradients. Instead they brace the valves against the high pressure, preventing regurgitation of ventricular blood back into the atrial cavities. [WP,unvetted]." [Wikipedia:Papillary_muscle] subset: uberon_slim synonym: "papillary muscle of ventricle" EXACT [MA:0002800] synonym: "ventricular papillary muscle" EXACT [MA:0002800] synonym: "ventricule papillary muscle" EXACT [] xref: EHDAA:8655 ! papillary muscles xref: FMA:12154 ! Papillary muscle xref: VHOG:0001392 ! papillary muscle xref: MA:0002800 ! papillary muscle xref: OpenCyc:Mx4rDid0jLYYEduAAAACs2IKfQ xref: ncithesaurus:Papillary_Muscle ! Papillary Muscle xref: GAID:175 ! papillary muscle xref: galen:PapillaryMuscle ! papillary muscle xref: OpenCyc:Mx4rDid0jLYYEduAAAACs2IKfQ ! papillary muscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/87/Papillary_muscles.png/200px-Papillary_muscles.png xref: MESH:A02.633.580.680 ! papillary muscle is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002082 ! cardiac ventricle xref: SCTID:279329009 ! Entire papillary muscle synonym: "musculus papillaris" RELATED LATIN [Wikipedia:Papillary_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/8/87/Papillary_muscles.png property_value: homology_notes "On the internal or parietal surface of the left ventricle in man and in mammals are two papillary muscles, which are almost identical and well developed.[well established][VHOG]" xsd:string {external_class="VHOG:0001392", ontology="VHOG", source="DOI:10.1111/j.1368-5031.2005.00345.x", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0030352 [Term] id: UBERON:0004523 name: papillary muscle of right ventricle def: "A papillary muscle that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic] xref: FMA:7259 ! Papillary muscle of right ventricle intersection_of: UBERON:0002494 ! papillary muscle intersection_of: part_of UBERON:0002080 ! part_of right ventricle xref: EHDAA2:0004544 ! right ventricle papillary muscles xref: SCTID:244356004 ! Entire papillary muscles of right ventricle [Term] id: UBERON:0004524 name: papillary muscle of left ventricle def: "A papillary muscle that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic] xref: FMA:9352 ! Papillary muscle of left ventricle intersection_of: UBERON:0002494 ! papillary muscle intersection_of: part_of UBERON:0002084 ! part_of left ventricle xref: EHDAA2:0001398 ! left ventricle papillary muscles xref: SCTID:244347007 ! Entire papillary muscles of left ventricle [Term] id: UBERON:0002495 name: long bone def: "Long bone is a limb bone that is subcylindrical and has a shaft with periosteum separating the ends of the bones. Long bones are present only in the limbs[VSAO]." [VSAO:wd, Wikipedia:Long_bone] comment: Endochondral_ossification is an essential process during the rudimentary formation of long bones, with the exception of the clavicle[Wikipedia:Endochondral_ossification]. The medial and and lateral ends undergo EO, the mid-portion is formed by a process with features of EO & IO (the process is shared by the mandible)[ISBN:9780397517251] subset: uberon_slim xref: FMA:7474 ! Long bone xref: MA:0002802 ! long bone xref: OpenCyc:Mx4rv6axr5wpEbGdrcN5Y29ycA xref: ncithesaurus:Long_Bone ! Long Bone xref: galen:LongBone ! long bone xref: OpenCyc:Mx4rv6axr5wpEbGdrcN5Y29ycA ! long bone xref: BTO:0004256 ! long bone is_a: UBERON:0001474 ! bone element relationship: part_of UBERON:0002091 ! appendicular skeleton xref: SCTID:332709000 ! Entire long bone xref: UMLS:C0222647 [Term] id: UBERON:0002496 name: stapes base subset: uberon_slim synonym: "base of stapes" RELATED [MA:0002804] synonym: "footplate" RELATED INCONSISTENT [FMA:52769] synonym: "stapes footplate" RELATED [MA:0002804] xref: FMA:52769 ! Base of stapes xref: MA:0002804 ! stapes base is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001687 {source="MA"} ! stapes xref: SCTID:279685009 ! Entire base of stapes [Term] id: UBERON:0002497 name: acromion def: "Region of the scapula where the latter meets with the clavicle: attachment point of the clavicle to the scapula in some taxa." [VSAO:0005067, Wikipedia:Acromion] subset: uberon_slim synonym: "acromion of the scapula" RELATED [Wikipedia:Acromion] synonym: "acromion process" EXACT [VSAO:0005067] synonym: "scapular acromion" EXACT [VSAO:0005067] xref: AAO:0000826 ! acromion xref: FMA:23260 ! Acromion xref: MA:0002805 ! acromion xref: ncithesaurus:Acromion ! Acromion xref: GAID:187 ! acromion xref: OpenCyc:Mx4rvmrF8pwpEbGdrcN5Y29ycA ! acromion xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/79/Gray206.png/200px-Gray206.png xref: EMAPA:25119 ! acromion xref: MESH:A02.835.232.087.783.261 ! acromion is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0001124 {source="FMA"} ! pectoral limb scapula xref: SCTID:181911000 ! Entire acromion xref: VSAO:0005067 ! scapular acromion xref: http://upload.wikimedia.org/wikipedia/commons/7/79/Gray206.png property_value: external_definition "Anterior rounded projection of the pars acromialis of the scapula.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000826", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of pars acromialis (AAO:0000752)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000826", date_retrieved="2012-06-20"} xref: UMLS:C0001209 [Term] id: UBERON:0002498 name: deltopectoral crest def: "The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. [WP,unvetted]." [Wikipedia:Deltoid_tuberosity] subset: uberon_slim synonym: "tuberositas deltoidea (corpus humeri)" EXACT [] synonym: "deltoid tuberosity" EXACT [FMA:23418] synonym: "deltoid crest" EXACT [MP:0004353] synonym: "deltoid eminence" EXACT [MP:0004353] synonym: "deltoid impression" EXACT [MP:0004353] synonym: "deltoid process" EXACT [MP:0004353] synonym: "tuberositas deltoidea" EXACT LATIN [FMA:TA, FMA:23418] synonym: "crista ventralis" EXACT [AAO:0000736] synonym: "crista ventralis humeri" RELATED [AAO:0000736] synonym: "deltoid crest" RELATED [AAO:0000736] synonym: "deltoid tuberosity of humerus" EXACT [FMA:23418] xref: FMA:23418 ! deltoid tuberosity of humerus xref: MA:0002808 ! deltoid tuberosity xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/HumerusFront.png/200px-HumerusFront.png xref: EMAPA:25052 ! deltoid tuberosity xref: AAO:0000736 ! crista ventralis is_a: UBERON:0005813 ! tubercle relationship: part_of UBERON:0004652 ! humerus diaphysis synonym: "tuberositas deltoidea humeri" EXACT LATIN [Wikipedia:Deltoid_tuberosity] xref: http://upload.wikimedia.org/wikipedia/commons/a/a7/HumerusFront.png [Term] id: UBERON:0011187 name: greater tubercle of humerus def: "The greater tubercle of the humerus is situated lateral to the head of the humerus and posteriolateral to the lesser tubercle. Its upper surface is rounded and marked by three flat impressions. the highest of these gives (\"superior facet\") insertion to the Supraspinatus the middle (\"middle facet\") to the Infraspinatus. the lowest one (\"inferior facet\"), and the body of the bone for about 2.5 cm. below it, to the Teres minor. The lateral surface of the greater tubercle is convex, rough, and continuous with the lateral surface of the body. Between the greater tubercle and the lesser tubercle is the intertubercular sulcus (bicipital groove)." [Wikipedia:Greater_tubercle] synonym: "greater tubercle of the humerus" RELATED [Wikipedia:Greater_tubercle] synonym: "greater tuberosity" RELATED [Wikipedia:Greater_tubercle] synonym: "greater tubercle" EXACT [FMA:23390] synonym: "greater tuberosity of humerus" EXACT [FMA:23390] synonym: "tuberculum majus" EXACT LATIN [FMA:TA] synonym: "tuberculum majus humeri" EXACT [Wikipedia:Greater_tubercle] is_a: UBERON:0005813 {source="FMA"} ! tubercle relationship: part_of UBERON:0004411 {source="FMA"} ! proximal epiphysis of humerus xref: FMA:23390 ! greater tubercle of humerus xref: SCTID:181934009 ! Entire greater tuberosity of humerus xref: ncithesaurus:Greater_Tuberosity ! greater tuberosity xref: http://upload.wikimedia.org/wikipedia/commons/3/3b/Gray326.png xref: UMLS:C1512275 [Term] id: UBERON:0011188 name: lesser tubercle of humerus def: "The lesser tubercle of the humerus, although smaller, is more prominent than the greater tubercle: it is situated in front, and is directed medially and anteriorly. Above and in front it presents an impression for the insertion of the tendon of the Subscapularis." [Wikipedia:Lesser_tubercle] synonym: "lesser tubercle of humerus" RELATED [Wikipedia:Lesser_tubercle] synonym: "lesser tubercle of the humerus" RELATED [Wikipedia:Lesser_tubercle] synonym: "lesser tubercle" EXACT [FMA:23393] synonym: "lesser tuberosity of humerus" EXACT [FMA:23393] synonym: "tuberculum minus" EXACT LATIN [FMA:TA] is_a: UBERON:0005813 {source="FMA"} ! tubercle relationship: part_of UBERON:0004411 {source="FMA"} ! proximal epiphysis of humerus xref: FMA:23393 ! lesser tubercle of humerus xref: SCTID:181935005 ! Entire lesser tuberosity of humerus xref: ncithesaurus:Lesser_Tuberosity ! lesser tuberosity xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Tuberculumminushumeri.png xref: UMLS:C0223687 [Term] id: UBERON:0002499 name: cochlear labyrinth def: "The labyrinth is a system of fluid passages in the inner ear, including both the cochlea, which is part of the auditory system, and the vestibular system, which provides the sense of balance. It is named by analogy with the mythical maze that imprisoned the Minotaur, because of its appearance. The bony labyrinth, or osseous labyrinth, is the network of passages with bony walls lined with periosteum. The bony labyrinth is lined with the membranous labyrinth. There is a layer of perilymph between them. The three parts of the bony labyrinth are the vestibule of the ear, the semicircular canals, and the cochlea. The vestibular system is the region of the inner ear where the semicircular canals converge, close to the cochlea (the hearing organ). The vestibular system works with the visual system to keep objects in focus when the head is moving. Joint and muscle receptors also are important in maintaining balance. The brain receives, interprets, and processes the information from these systems that control our balance. [WP,unvetted]." [Wikipedia:Cochlear_labyrinth] comment: Editor notes: we follow the FMA in placing this in the membranous labyrinth. Notes: The labyrinth can be divided by layer or by region. Bony vs. membranous / Vestibular vs. cochlear subset: uberon_slim xref: FMA:61259 ! Cochlear labyrinth xref: MA:0002809 ! cochlear labyrinth xref: ncithesaurus:Cochlear_Labyrinth ! Cochlear Labyrinth xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/19/Gray923.png/200px-Gray923.png xref: BTO:0004686 ! cochlear labyrinth is_a: UBERON:0000064 ! organ part relationship: located_in UBERON:0001844 ! cochlea relationship: part_of UBERON:0001849 {source="FMA"} ! membranous labyrinth xref: UMLS:C0931689 [Term] id: UBERON:0002501 name: oval window def: "The oval window (or vestibular window) is a membrane-covered opening which leads from the middle ear to the vestibule of the inner ear. Vibrations that come into contact with the tympanic membrane travel through the three ossicles and into the inner ear. The oval window is the intersection of the middle ear with the inner ear, and is directly contacted by the stapes; by the time vibrations reach the oval window, they have been amplified over twenty times from what they were when they contacted the tympanic membrane, a testament to the amplifying power of the middle ear. It is a reniform (kidney-shaped) opening leading from the tympanic cavity into the vestibule of the internal ear; its long diameter is horizontal, and its convex border is upward. In the recent state it is occupied by the base of the stapes, the circumference of which is fixed by the annular ligament to the margin of the foramen. [WP,unvetted]." [Wikipedia:Oval_window] subset: uberon_slim synonym: "oval window of petrous part of temporal bone" EXACT [] synonym: "vestibular window" RELATED [MA:0002813] xref: FMA:56913 ! Oval window xref: MA:0002813 ! oval window xref: GAID:882 ! oval window xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9d/Gray911.png/200px-Gray911.png xref: MESH:A09.246.631.909.551 ! oval window is_a: UBERON:0000161 ! orifice relationship: part_of UBERON:0001694 ! petrous part of temporal bone synonym: "fenestra vestibuli" RELATED LATIN [Wikipedia:Oval_window] synonym: "fenestra ovalis" RELATED LATIN [Wikipedia:Oval_window] xref: http://upload.wikimedia.org/wikipedia/commons/9/9d/Gray911.png xref: SCTID:362561009 ! Entire vestibular window [Term] id: UBERON:0002502 name: round window def: "The round window is one of the two openings into the cochlea of the inner ear. It is closed off from the middle ear by the round window membrane, which vibrates with opposite phase to vibrations entering the cochlea through the oval window. It allows fluid in the cochlea to move, which in turn ensures that hair cells of the basilar membrane will be stimulated and that audition will occur. [WP,unvetted]." [Wikipedia:Round_window] subset: uberon_slim synonym: "cochlear window" RELATED [MA:0002814] synonym: "round window of petrous part of temporal bone" EXACT [] xref: FMA:56932 ! Round window xref: MA:0002814 ! round window xref: GAID:878 ! round window xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9d/Gray911.png/200px-Gray911.png xref: MESH:A09.246.631.246.814 ! round window is_a: UBERON:0000161 ! orifice relationship: part_of UBERON:0001694 ! petrous part of temporal bone synonym: "fenestra cochleae" RELATED LATIN [Wikipedia:Round_window] synonym: "fenestra rotunda" RELATED LATIN [Wikipedia:Round_window] xref: http://upload.wikimedia.org/wikipedia/commons/9/9d/Gray911.png xref: SCTID:279785002 ! Entire cochlear window [Term] id: UBERON:1000022 name: Zymbal's gland def: "A modified sebaceous glands that are located at the base of the external ear and secrete into the auditory canal" [http://ctrgenpath.net/static/atlas/mousehistology/Windows/senses/zymbalgland.html] comment: Structure notes: Zymbal’s glands are located beneath squamous epithelium at the anterior and posterior aspect of the ear canal, and as a single external gland that is located anterior and ventral to the base of the external ear canal. The bilateral Zymbal’s glands are adjacent to the auditory canal and are made up of several lobules of modified sebaceous glands - http://ratguide.com/health/neoplasia/zymbals_gland_tumor.php. Editor notes: modified sebacious gland or subtype? synonym: "Zymbal gland" RELATED [MA:0002900] synonym: "gland of Zymbal" RELATED [] is_a: UBERON:0001821 {source="MA"} ! sebaceous gland relationship: part_of UBERON:0001691 {source="cjm"} ! external ear relationship: only_in_taxon NCBITaxon:9989 ! Rodenti xref: MA:0002900 ! zymbal gland xref: SCTID:105587007 ! Zymbal's gland xref: ncithesaurus:Zymbal_Gland xref: UMLS:C0687056 [Term] id: UBERON:0012102 ! buccal salivary gland name: buccal salivary gland is_a: UBERON:0001830 {source="FMA"} ! minor salivary gland relationship: part_of UBERON:0000165 {source="FMA"} ! mouth xref: FMA:59793 ! buccal salivary gland [Term] id: UBERON:0010241 name: molar gland comment: a variety of mammals have salivary glands variously terms upper molar/buccal gland - this class groups all of these intersection_of: UBERON:0001830 ! minor salivary gland intersection_of: part_of UBERON:0001567 ! cheek xref: FMA:59794 ! molar salivary gland synonym: "molar salivary gland" EXACT [FMA:59794] xref: SCTID:59637006 ! Molar gland def: "A minor salivary gland that is part of a cheek." [OBOL:automatic] [Term] id: UBERON:0010240 name: zygomatic gland def: "a salivary gland best developed in carnivores; located above the zygomatic arch and below the eye. Enlargement or mucocele of the gland causes exophthalmos" [http://medical-dictionary.thefreedictionary.com/zygomatic+gland] synonym: "orbital gland" RELATED [] synonym: "upper molar gland" RELATED [] synonym: "superior buccal gland" RELATED [] synonym: "superior buccal salivary gland" RELATED [] xref: ncithesaurus:Zygomatic_Gland ! Zygomatic Gland is_a: UBERON:0012102 ! buccal salivary gland relationship: part_of UBERON:0001567 ! cheek relationship: only_in_taxon NCBITaxon:33554 ! Carnivora xref: UMLS:C2700338 [Term] id: UBERON:0010242 name: anterior buccal gland synonym: "anterior buccal salivary gland" RELATED [] is_a: UBERON:0012102 ! buccal salivary gland relationship: part_of UBERON:0001567 ! cheek xref: MA:0002700 ! anterior buccal gland [Term] id: UBERON:0000980 name: trochanter def: "bony prominences near the upper extremity of the femur; there are two in human (greater and lesser trochanters) and three in many other mammalian species (greater, lesser and third); these normally serve as attachment points for hip and thigh muscles[MP]" [Wikipedia:Trochanter] subset: uberon_slim synonym: "femoral trochanter" EXACT [AAO:0000897] synonym: "trochanter of femur" EXACT [] xref: FMA:82513 ! Trochanter xref: MA:0002821 ! trochanter xref: AAO:0000897 ! femoral trochanter xref: ncithesaurus:Trochanter ! Trochanter xref: SCTID:182047004 ! Trochanter of femur is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000981 {source="MA"} ! femur property_value: external_definition "Process on the ventral surface of the shaft of the femur.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000897", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0162370 [Term] id: UBERON:0002503 name: greater trochanter def: "The greater trochanter (great trochanter) of the femur is a large, irregular, quadrilateral eminence and a part of the skeletal system. It is directed a little lateralward and backward, and, in the adult, is about 1 cm lower than the head. Because the pelvic outlet in the female is larger than in the male, there is a greater distance between the greater trochanters in the female. It has two surfaces and four borders. [WP,unvetted]." [Wikipedia:Greater_trochanter] subset: uberon_slim synonym: "greater trochanter of femur" EXACT [] synonym: "great trochanter" EXACT [] xref: FMA:32852 ! Greater trochanter xref: galen:GreaterTrochanter xref: MA:0002822 ! greater trochanter xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Gray243.png/200px-Gray243.png is_a: UBERON:0000980 ! trochanter relationship: part_of UBERON:0004412 {source="FMA"} ! proximal epiphysis of femur xref: SCTID:182050001 ! Entire greater trochanter of femur xref: ncithesaurus:Great_Trochanter ! great trochanter synonym: "trochanter major" RELATED LATIN [Wikipedia:Greater_trochanter] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Gray243.png xref: UMLS:C0223865 [Term] id: UBERON:0002504 name: lesser trochanter def: "The lesser trochanter (small trochanter) of the femur is a conical eminence, which varies in size in different subjects [WP,unvetted]." [Wikipedia:Lesser_trochanter] subset: uberon_slim synonym: "lesser trochanter of femur" EXACT [] xref: FMA:32853 ! Lesser trochanter xref: galen:LesserTrochanter xref: MA:0002823 ! lesser trochanter xref: ncithesaurus:Lesser_Trochanter ! Lesser Trochanter xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Gray341.png/200px-Gray341.png is_a: UBERON:0000980 ! trochanter relationship: part_of UBERON:0004412 {source="FMA"} ! proximal epiphysis of femur xref: SCTID:182051002 ! Entire lesser trochanter of femur synonym: "trochanter minor" RELATED LATIN [Wikipedia:Lesser_trochanter] xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray341.png xref: UMLS:C0223866 [Term] id: UBERON:0008786 name: third trochanter def: "The upper part of the gluteal tuberosity is often elongated into a roughened crest, on which a more or less well-marked, rounded tubercle, the third trochanter, is occasionally developed." [Wikipedia:Third_trochanter] is_a: UBERON:0000980 {source="Wikipedia"} ! trochanter relationship: part_of UBERON:0004412 {source="FMA"} ! proximal epiphysis of femur xref: FMA:75824 ! third trochanter synonym: "trochanter tertius" RELATED LATIN [Wikipedia:Third_trochanter] xref: http://upload.wikimedia.org/wikipedia/commons/2/2b/Third_trochanter-tweaked.png [Term] id: UBERON:0008787 name: fourth trochanter def: "a knob-like feature on the medial side of the femur that serves as a muscle attachment." [Wikipedia:Fourth_trochanter] comment: The fourth trochanter first appeared in the Erythrosuchidae, large basal archosaurian predators of the early Triassic period. This seemingly insignificant detail may have made the evolution of dinosaurs possible (all early dinosaurs and many later ones were bipeds), and may also be connected with the ability of the archosaurs or their immediate ancestors to survive the catastrophic Permian-Triassic extinction event[WP]. is_a: UBERON:0000980 {source="Wikipedia"} ! trochanter relationship: only_in_taxon NCBITaxon:8492 ! Archosauria [Term] id: UBERON:0002505 name: spiral modiolar artery def: "the artery which parallels the spiral ganglion in the root of the spiral lamina of the modiolus, serving the ganglion and the cochlear duct and its contents." [MP:0004629] xref: FMA:52312 ! Spiral modiolar artery xref: MA:0002824 ! spiral modiolar artery is_a: UBERON:0001637 ! artery xref: SCTID:149380004 ! Entire spiral modiolar artery [Term] id: UBERON:0007625 name: pigment epithelium of eye def: "epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules." [MP:0005200] synonym: "eye pigment epithelium" RELATED [MESH:A09.371.670] xref: MESH:A09.371.670 ! pigment epithelium of eye xref: GAID:907 ! pigment epithelium of eye intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000970 ! eye [Term] id: UBERON:0002506 name: iris epithelium def: "An epithelium that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "epithelium pigmentosum (iris)" EXACT [] synonym: "iris pigmented epithelium" RELATED [MA:0002826] synonym: "pigmented epithelium of iris" EXACT [] synonym: "epithelial tissue of iris" EXACT [OBOL:automatic] synonym: "epithelium of iris" EXACT [OBOL:automatic] synonym: "iris epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelium pigmentosum (iris)" EXACT [FMA:58517] synonym: "iris epithelium" EXACT [FMA:58517] synonym: "pigmented epithelium of iris" EXACT [FMA:58517] xref: FMA:58517 ! Epithelium of iris xref: MA:0002826 ! iris epithelium is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001769 ! iris relationship: part_of UBERON:0001769 {source="MA"} ! iris relationship: has_part GO:0048770 {source="MP"} ! pigment granule synonym: "epithelium pigmentosum iridis" EXACT LATIN [FMA:TA, FMA:58517] [Term] id: UBERON:0001778 name: ciliary epithelium def: "A double layer covering the ciliary body that produces aqueous humor." [Wikipedia:Ciliary_body#Ciliary_epithelium] synonym: "ocular ciliary epithelium" EXACT [] synonym: "epithelium of ciliary body" EXACT [FMA:58464] synonym: "ciliary body epithelium" EXACT [FMA:58464] xref: FMA:58464 ! Epithelium of ciliary body xref: MA:0001238 ! ciliary epithelium xref: ncithesaurus:Ciliary_Epithelium ! Ciliary Epithelium xref: BTO:0001770 ! ciliary epithelium is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001775 ! ciliary body relationship: has_part GO:0048770 {source="MP"} ! pigment granule relationship: part_of UBERON:0001775 {source="MA"} ! ciliary body relationship: secretes UBERON:0001796 {source="Wikipedia"} ! aqueous humor of eyeball xref: SCTID:280870004 ! Entire ciliary epithelium xref: UMLS:C0459736 [Term] id: UBERON:0002507 name: abdominal lymph node def: "A lymph node that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "lymph node of abdomen" EXACT [] synonym: "abdomen lymph node" EXACT [OBOL:automatic] xref: FMA:12787 ! Abdominal lymph node xref: MA:0002827 ! abdominal lymph node is_a: UBERON:0000029 ! lymph node intersection_of: UBERON:0000029 ! lymph node intersection_of: part_of UBERON:0000916 ! abdomen xref: SCTID:245342005 ! Entire abdominal lymph node [Term] id: UBERON:0002508 name: celiac lymph node def: "The visceral glands are associated with the branches of the celiac, superior and inferior mesenteric arteries. Those related to the branches of the celiac artery (the celiac lymph nodes) form three sets, gastric, hepatic, and pancreaticolienal. gastric lymph nodes, hepatic lymph nodes, splenic lymph nodes [WP,unvetted]." [Wikipedia:Celiac_lymph_node] subset: uberon_slim synonym: "celiac node" EXACT [] synonym: "coeliac node" EXACT [] synonym: "nodus lymphaticus coeliacus" EXACT [] synonym: "terminal ventral aortic node" EXACT [] xref: FMA:12792 ! Celiac lymph node xref: MA:0002828 ! celiac lymph node xref: ncithesaurus:Celiac_Lymph_Node ! Celiac Lymph Node xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/71/Gray613.png/200px-Gray613.png is_a: UBERON:0002507 ! abdominal lymph node xref: SCTID:245343000 ! Entire celiac lymph node xref: UMLS:C0229766 [Term] id: UBERON:0002509 name: mesenteric lymph node def: "the lymph nodes located in the mesentery, of which there are 3 classes: ileocolic, juxtaintestinal mesenteric, and central superior group." [MP:0005232] synonym: "mesenteric node" EXACT [] synonym: "nodi lymphoidei mesenterici" RELATED [BTO:0000767] xref: BTO:0000767 xref: FMA:12795 ! Mesenteric lymph node xref: MA:0002829 ! mesenteric lymph node is_a: UBERON:0002507 ! abdominal lymph node intersection_of: UBERON:0002507 ! abdominal lymph node intersection_of: part_of UBERON:0002095 ! mesentery xref: ncithesaurus:Mesenteric_Lymph_Node ! Mesenteric Lymph Node xref: UMLS:C0229792 [Term] id: UBERON:0002510 name: anterior fontanel def: "In humans, the anterior fontanelle (bregmatic fontanelle, frontal fontanelle) is the largest, and is placed at the junction of the sagittal suture, coronal suture, and frontal suture; it is lozenge-shaped, and measures about 4 cm in its antero-posterior and 2.5 cm in its transverse diameter. The fontanelle allows the skull to deform during birth to ease its passage through the birth canal and for expansion of the brain after birth. While the posterior and lateral fontanelles are obliterated by about six months after birth, the anterior is not completely closed until about the middle of the second year. Full ossification starts in the late twenties and finishes before the age of 50 . [WP,unvetted]." [Wikipedia:Anterior_fontanelle] comment: AO notes TAO:0001739 anterior cranial fontanel is 'Fontanel that is located between the contralateral frontals and anterior to the epiphyseal bar' synonym: "anterior fontanelle" EXACT [FMA:75439] synonym: "bregmatic fontanelle" RELATED [Wikipedia:Anterior_fontanelle] synonym: "frontal fontanelle" RELATED [Wikipedia:Anterior_fontanelle] synonym: "fonticulus anterior" RELATED LATIN [Wikipedia:Anterior_fontanelle] xref: FMA:75439 ! Anterior fontanelle xref: MA:0002830 ! anterior fontanel xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/Gray197.png/200px-Gray197.png xref: EMAPA:19199 ! anterior fontanelle xref: SCTID:244680006 ! Entire anterior fontanel of skull intersection_of: UBERON:0002221 ! fontanelle intersection_of: connects UBERON:0002489 ! coronal suture intersection_of: connects UBERON:0002490 ! frontal suture intersection_of: connects UBERON:0002492 ! sagittal suture xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/Gray197.png [Term] id: UBERON:0002512 name: corpus luteum def: "a transient endocrine gland that develops from the postovulatory or atretic follicles and secretes progesterone; it is thought to be related to egg retention[PMID]." [Wikipedia:Corpus_luteum, PMID:20959416] comment: Taxon notes: maintains the endometrium in mammals[WP]. A corpus luteum is known in hagfish (100), Squalus (101), and salamander (100) but not lamprey (102). There are no data for Branchiostoma and Ciona, and given that they are multiple spawners, there is no a priori reason to conclude that they lack a corpus luteum[PMID:20959416] subset: uberon_slim synonym: "corpora lutea" EXACT PLURAL [] synonym: "corpus luteum of ovary" EXACT [] synonym: "luteal gland" RELATED [BTO:0000292] xref: BTO:0000292 xref: FMA:18619 ! Corpus luteum xref: MA:0002834 ! corpus luteum xref: ncithesaurus:Corpus_Luteum ! Corpus Luteum xref: GAID:369 ! corpus luteum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/57/Folliclesinovary.jpg/200px-Folliclesinovary.jpg xref: EMAPA:29886 ! corpus luteum xref: MESH:A05.360.319.114.630.278 ! corpus luteum is_a: UBERON:0002368 {source="PMID:20959416"} ! endocrine gland relationship: develops_from UBERON:0001305 ! follicle of ovary relationship: part_of UBERON:0000949 {source="MA"} ! endocrine system relationship: part_of UBERON:0000992 {source="MA"} ! female gonad relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: capable_of GO:0042701 ! progesterone secretion relationship: present_in_taxon NCBITaxon:71164 {source="PMID:20959416"} ! hagfish xref: SCTID:257943001 ! Entire corpus luteum of ovary xref: http://upload.wikimedia.org/wikipedia/commons/5/57/Folliclesinovary.jpg xref: UMLS:C0010092 [Term] id: UBERON:0010362 name: endoskeleton def: "Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues[VSAO]." [VSAO:0000037, Wikipedia:Endoskeleton] synonym: "replacement skeleton" EXACT [VSAO:curator] is_a: UBERON:0010912 {source="VSAO"} ! subdivision of skeleton relationship: composed_primarily_of UBERON:0010522 ! replacement element xref: VSAO:0000037 ! endoskeleton xref: XAO:0004026 ! endoskeleton property_value: external_definition "An endoskeleton is an internal support structure of an animal, composed of mineralized tissue. Endoskeleton develops within the skin or in the deeper body tissues. The vertebrate is basically an endoskeleton made up of two types of tissues (bone and cartilage). During early embryonic development the endoskeleton is composed of notochord and cartilage. The notochord in most vertebrates is replaced by vertebral column and cartilage is replaced by bone in most adults. In three phyla and one subclass of animals, endoskeletons of various complexity are found: Chordata, Echinodermata, Porifera, and Coleoidea. An endoskeleton may function purely for support (as in the case of sponges), but often serves as an attachment site for muscle and a mechanism for transmitting muscular forces. A true endoskeleton is derived from mesodermal tissue. Such a skeleton is present in echinoderms and chordates. The poriferan 'skeleton' consists of microscopic calcareous or siliceous spicules or a spongin network. The Coleoidae do not have a true endoskeleton in the evolutionary sense; here, a mollusk exoskeleton evolved into several sorts of internal structure, the \"cuttlebone\" of cuttlefish being the best-known version. Yet they do have cartilaginous tissue in their body, even if it is not mineralized, especially in the head, where it forms a primitive cranium. The endoskeleton gives shape,support and protection to the body and provides a mean of locomotion.[Wikipedia:Endoskeleton]t" xsd:string {source="Wikipedia:Endoskeleton"} [Term] id: UBERON:0010522 name: replacement element def: "Skeletal element that forms as a replacement or substitution of another element or tissue." [VSAO:0000135] is_a: UBERON:0004765 {source="VSAO"} ! skeletal element relationship: part_of UBERON:0010362 {source="cjm"} ! endoskeleton xref: VSAO:0000135 ! replacement element xref: XAO:0004016 ! replacement element xref: ZFA:0005624 ! replacement element [Term] id: UBERON:0010363 name: endochondral element def: "A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification." [VSAO:0000139] synonym: "endochondral replacement element" EXACT [VSAO:0000139] is_a: UBERON:0004765 {source="VSAO"} ! skeletal element xref: VSAO:0000139 ! endochondral element xref: ZFA:0005620 ! endochondral element xref: XAO:0004017 ! endochondral element property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000009" xsd:anyURI [Term] id: UBERON:0012075 name: replacement bone def: "Bone that forms as a replacement of another structural tissue." [ZFA:0001628] comment: This class was introduced to be consistent with the ZFA hierarchy. The corresponding TAO term was obsoleted, and never introduced into VSAO. Note that VSAO does have replacement element. synonym: "replacement bones" EXACT PLURAL [ZFA:0001628] xref: ZFA:0001628 ! replacement bone xref: AAO:0010768 ! replacement bone xref: TAO:0001637 ! replacement bone is_a: UBERON:0001474 {source="ZFA"} ! bone element is_a: UBERON:0010522 {source="ZFA"} ! replacement element property_value: external_definition "Bone that forms as a replacement of another structural tissue.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001637", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0008911 name: chondral bone def: "Replacement bone that forms within or surrounding a cartilaginous skeletal element." [zfin:curator] comment: This class was introduced to be consistent with the ZFA hierarchy. The term was never introduced into VSAO. is_a: UBERON:0012075 {source="ZFA"} ! replacement bone xref: ZFA:0001693 ! chondral bone xref: AAO:0010774 ! chondral bone [Term] id: UBERON:0008909 name: perichordal bone def: "Bone element that is adjacent to the notochord." [VSAO:0000307] comment: Editor notes: We go with the latest VSAO in making this a subtype of bone, and add a logical definition based on the textual definition in VSAO. We also include the subtyping under 'replacement bone', for consistency with ZFA is_a: UBERON:0012075 {source="ZFA", notes="not in VSAO"} ! replacement bone intersection_of: UBERON:0001474 ! bone element intersection_of: adjacent_to UBERON:0002328 ! notochord synonym: "perichordal bones" EXACT PLURAL [ZFA:0001629] synonym: "perichordal bone" RELATED [ZFA:0001629] disjoint_from: UBERON:0008913 ! perichondral bone xref: TAO:0001639 ! perichordal bone xref: AAO:0010777 ! perichordal bone xref: ZFA:0001629 ! perichordal bone xref: VSAO:0000307 ! perichordal bone property_value: external_definition "Replacement bone that forms within the connective tissue surrounding the notochord.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001639", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0008913 ! perichondral bone name: perichondral bone def: "Bone element that is located on the surface of a cartilage element." [VSAO:0000308] comment: include the subtyping under 'replacement bone', for consistency with ZFA, but VSAO does not include this intermediate class synonym: "perichondral bones" EXACT PLURAL [ZFA:0001630] synonym: "perichondral bone" RELATED [ZFA:0001630] xref: TAO:0001638 ! perichondral bone is_a: UBERON:0007842 {source="VSAO"} ! membrane bone relationship: develops_from UBERON:0002222 {source="ZFA"} ! perichondrium relationship: participates_in GO:0036073 {source="VSAO"} ! perichondral ossification xref: ZFA:0001630 ! perichondral bone xref: AAO:0010779 ! perichondral bone xref: VSAO:0000308 ! perichondral bone property_value: external_definition "Replacement bone that forms within the connective tissue surrounding cartilage.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001638", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0004763 name: endochondral bone tissue def: "Replacement bone tissue that forms within cartilage[VSAO, modified]." [Wikipedia:Endochondral_ossification, GO:0001958, VSAO:0000145] comment: The text and logical definition of this term was modified from the definition of 'endochondral bone' in ZFA. AO notes: note the distinction between endochondral bone and endochondral bone tissue. Some bones may be a mixture of both tissue types. The MA class most likely refers to a tissue type subset: uberon_slim subset: vertebrate_core xref: MA:0002836 ! endochondral bone intersection_of: UBERON:0002481 ! bone tissue intersection_of: output_of GO:0001958 ! endochondral ossification relationship: developmentally_replaces UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0002513 ! endochondral bone disjoint_from: UBERON:0004764 ! intramembranous bone tissue [Term] id: UBERON:0004764 name: intramembranous bone tissue def: "Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [Wikipedia:Intramembranous_ossification, GO:0001957] comment: note the distinction between intramembranous bone and intramembranous bone tissue. Some bones may be a mixture of both tissue types. The MA class most likely refers to a tissue type (it is under bone tissue and connective tissue; there are no child classes) xref: MA:0002837 ! intramembranous bone intersection_of: UBERON:0002481 ! bone tissue intersection_of: output_of GO:0001957 ! intramembranous ossification relationship: part_of UBERON:0002514 ! intramembranous bone relationship: develops_from UBERON:0003104 ! mesenchyme [Term] id: UBERON:0009859 name: endosteum def: "a thin layer of connective tissue that lines the surface of the bony tissue that forms the medullary cavity of long bones" [Wikipedia:Endosteum] is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0002495 ! long bone relationship: composed_primarily_of UBERON:0011825 ! loose connective tissue relationship: adjacent_to UBERON:0002484 ! bone marrow cavity xref: FMA:32692 ! endosteum xref: SCTID:57487002 ! Endosteum xref: ncithesaurus:Endosteum ! Endosteum xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Illu_long_bone.jpg property_value: has_relational_adjective "endosteal" xsd:string xref: UMLS:C0222658 [Term] id: UBERON:0002515 name: periosteum def: "Periosteum is a membrane that lines the outer surface of all bones, except at the joints of long bones. Endosteum lines the inner surface of all bones. Periosteum consists of dense irregular connective tissue. Periosteum is divided into an outer 'fibrous layer' and inner 'cambium layer' (or 'osteogenic layer'). The fibrous layer contains fibroblasts, while the cambium layer contains progenitor cells that develop into osteoblasts. These osteoblasts are responsible for increasing the width of a long bone and the overall size of the other bone types. After a bone fracture the progenitor cells develop into osteoblasts and chondroblasts, which are essential to the healing process. As opposed to osseous tissue, periosteum has nociceptors nerve endings, making it very sensitive to manipulation. It also provides nourishment by providing the blood supply. Periosteum is attached to bone by strong collagenous fibers called Sharpey's fibres, which extend to the outer circumferential and interstitial lamellae. It also provides an attachment for muscles and tendons. Periosteum that covers the outer surface of the bones of the skull is known as 'pericranium'. [WP,unvetted]." [Wikipedia:Periosteum] subset: uberon_slim xref: BTO:0001022 xref: FMA:24041 ! Periosteum xref: MA:0002838 ! periosteum xref: ncithesaurus:Periosteum ! Periosteum xref: GAID:925 ! periosteum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Bone_growth.png/200px-Bone_growth.png xref: MESH:A10.165.265.746 ! periosteum is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0001474 ! bone element relationship: composed_primarily_of UBERON:0011822 ! dense irregular connective tissue xref: galen:PeriOsteum xref: SCTID:33840008 ! Periosteum xref: http://upload.wikimedia.org/wikipedia/commons/c/cf/Bone_growth.png property_value: has_relational_adjective "periosteal" xsd:string xref: UMLS:C0031110 [Term] id: UBERON:0000312 name: inner cambium layer of periosteum synonym: "cambium" EXACT [] synonym: "cambial layer" EXACT [FMA:234358] synonym: "cambium layer of periosteum" EXACT [FMA:234358] synonym: "osteogenic layer of periosteum" EXACT [Wikipedia:Periosteum] synonym: "inner cambial layer of periosteum" EXACT [FMA:234358] synonym: "cambial layer of periosteum" EXACT [FMA:234358] synonym: "internal layer of periosteum" EXACT [] synonym: "internal periosteum" EXACT [] xref: FMA:234358 ! Cambial layer of periosteum is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0002515 {source="FMA"} ! periosteum relationship: composed_primarily_of UBERON:0011824 ! fibrous connective tissue relationship: has_part CL:0000375 {source="Wikipedia"} ! osteoprogenitor cell [Term] id: UBERON:0009858 ! outer fibrous layer of periosteum name: outer fibrous layer of periosteum synonym: "fibrous layer of periosteum" EXACT [FMA:234354] synonym: "outer fibrous layer of periosteum" EXACT [FMA:234354] synonym: "capsular layer of periosteum" EXACT [FMA:234354] synonym: "external layer of periosteum" EXACT [] synonym: "external periosteum" EXACT [] is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0002515 {source="FMA"} ! periosteum relationship: has_part CL:0000057 {source="Wikipedia"} ! fibroblast relationship: composed_primarily_of UBERON:0011822 ! dense irregular connective tissue xref: FMA:234354 ! capsular layer of periosteum [Term] id: UBERON:0008956 name: involucrum def: "a layer of new bone growth outside existing bone seen in pyogenic osteomyelitis. It results from the stripping off of the periosteum by the accumulation of pus within the bone, and new bone growing from the periosteum." [Wikipedia:Involucrum] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001474 {source="Wikipedia"} ! bone element [Term] id: UBERON:0008957 name: sequestrum def: "a piece of dead bone that has become separated during the process of necrosis from normal/sound bone.." [Wikipedia:Sequestrum] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001474 {source="Wikipedia"} ! bone element [Term] id: UBERON:0008958 name: cetacean involucrum synonym: "whale involucrum" RELATED [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001474 {source="Wikipedia:Evolution_of_cetaceans"} ! bone element relationship: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: only_in_taxon NCBITaxon:9721 ! Cetacea [Term] id: UBERON:0004129 name: growth plate cartilage def: "cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow." [GO:0003417] synonym: "growth plate" RELATED [] is_a: UBERON:0002418 ! cartilage tissue relationship: surrounds UBERON:0002513 ! endochondral bone relationship: site_of GO:0030282 ! bone mineralization [Term] id: UBERON:0002516 ! epiphyseal plate name: epiphyseal plate def: "a hyaline cartilage plate in the metaphysis at each end of a long bone. The plate is found in children and adolescents; in adults, who have stopped growing, the plate is replaced by an epiphyseal line." [Wikipedia:Epiphyseal_plate] comment: editor note: consider splitting this class into the epiphyseal plates of long bones and vertebrae subset: uberon_slim synonym: "epiphyseal cartilage" RELATED [] synonym: "epiphyseal growth plate cartilage" EXACT [] synonym: "epiphyseal growth plate" EXACT [] synonym: "growth plate" RELATED [MA:0002839] synonym: "long bone epiphyseal plate" EXACT [MA:0002839] synonym: "epiphysial plate" EXACT [FMA:75427] synonym: "cartilago epiphysialis" RELATED [BTO:0000412] synonym: "epiphyseal disk" RELATED [BTO:0000412] synonym: "epiphyseal growth disk" RELATED [BTO:0000412] synonym: "physis" RELATED [BTO:0000412] xref: FMA:75427 ! Epiphysial plate xref: MA:0002839 ! long bone epiphyseal plate xref: BTO:0000412 ! epiphyseal growth plate xref: GAID:191 ! growth plate xref: EMAPA:25059 ! epiphyseal plate of digit 1 of fore-paw xref: EMAPA:25062 ! epiphyseal plate of digit 2 of fore-paw xref: EMAPA:25065 ! epiphyseal plate of digit 3 of fore-paw xref: EMAPA:25068 ! epiphyseal plate of digit 4 of fore-paw xref: EMAPA:25071 ! epiphyseal plate of digit 5 of fore-paw xref: MESH:A02.835.232.251.352 ! growth plate is_a: UBERON:0001994 ! hyaline cartilage relationship: part_of UBERON:0001438 ! metaphysis xref: SCTID:84349008 ! Epiphyseal plate synonym: "lamina epiphysialis" RELATED LATIN [Wikipedia:Epiphyseal_plate] xref: http://upload.wikimedia.org/wikipedia/commons/7/7a/Tib_fib_growth_plates.jpg [Term] id: UBERON:0006768 name: epiphyseal line synonym: "epiphysial junction" EXACT [FMA:9918] synonym: "line of bony union" EXACT [FMA:9918] xref: FMA:9918 ! epiphysial junction is_a: UBERON:0010361 {source="FMA"} ! synostosis relationship: part_of UBERON:0001438 ! metaphysis relationship: develops_from UBERON:0002516 ! epiphyseal plate xref: SCTID:333108008 ! Entire epiphyseal line [Term] id: UBERON:0006771 name: long bone epiphyseal plate proliferative zone def: "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix[MP]." [MP:0003662] comment: In this zone, chondrocytes undergo rapid mitosis, forming distinctive looking stacks[WP] synonym: "epiphyseal plate proliferative zone" EXACT [] synonym: "zone of proliferation" RELATED [MA:0002976] xref: MA:0002976 ! long bone epiphyseal plate proliferative zone is_a: UBERON:0006775 ! zone of epiphyseal plate relationship: site_of GO:0070278 ! extracellular matrix constituent secretion relationship: site_of GO:0008283 ! cell proliferation [Term] id: UBERON:0006772 name: long bone epiphyseal plate hypertrophic zone def: "the layer of the epiphyseal plate of a long bone where chondrocytes mature and enlarge[MP]." [MP:0000165, https://sourceforge.net/tracker/?func=detail&aid=3442184&group_id=76834&atid=1205376] comment: note that there is also MA:0002849 ! hypertrophic cartilage zone synonym: "epiphyseal plate hypertrophic zone" EXACT [] synonym: "maturation zone" RELATED [MA:0002977] synonym: "zone of hypertrophic chondrocytes" RELATED [MA:0002977] synonym: "hypertrophic chondrocyte zone" RELATED [MP:0000165] synonym: "long bone hypertrophic chondrocyte zone" RELATED [MP:0000165] xref: MA:0002977 ! long bone epiphyseal plate hypertrophic zone is_a: UBERON:0006775 ! zone of epiphyseal plate relationship: site_of GO:0003415 ! chondrocyte hypertrophy relationship: site_of GO:0002063 ! chondrocyte development [Term] id: UBERON:0006773 name: long bone epiphyseal plate ossification zone def: "layer of the epiphyseal plate where new bone matrix is deposited[MP]." [MP:0006399] synonym: "epiphyseal plate ossification zone" EXACT [] is_a: UBERON:0006775 ! zone of epiphyseal plate [Term] id: UBERON:0006775 ! zone of epiphyseal plate name: zone of epiphyseal plate is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0002516 ! epiphyseal plate [Term] id: UBERON:0002520 name: submandibular lymph node def: "The submandibular lymph nodes (submaxillary glands in older texts), three to six in number, are placed beneath the body of the mandible in the submaxillary triangle, and rest on the superficial surface of the submaxillary salivary gland. One gland, the middle gland of Stahr, which lies on the external maxillary artery as it turns over the mandible, is the most constant of the series; small lymph glands are sometimes found on the deep surface of the submaxillary salivary glands. The afferents of the submaxillary glands drain the medial palpebral commissure, the cheek, the side of the nose, the upper lip, the lateral part of the lower lip, the gums, and the anterior part of the margin of the tongue. Efferent vessels from the facial and submental glands also enter the submaxillary glands. Their efferent vessels pass to the superior deep cervical glands. [WP,unvetted]." [Wikipedia:Submandibular_lymph_node] subset: uberon_slim synonym: "level ib neck node" EXACT [] synonym: "submandibular node" EXACT [] synonym: "nodi lymphoidei submandibulares" RELATED [BTO:0000769] xref: BTO:0000769 xref: FMA:61224 ! Submandibular lymph node xref: MA:0002843 ! submandibular lymph node xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Illu_quiz_hn_03.jpg/200px-Illu_quiz_hn_03.jpg is_a: UBERON:0003968 {source="CL:tm"} ! peripheral lymph node xref: ncithesaurus:Submandibular_Lymph_Node ! Submandibular Lymph Node xref: SCTID:245319003 ! Entire submandibular lymph node xref: UMLS:C0229722 [Term] id: UBERON:0002521 name: elastic tissue def: "Elastic fibers (or yellow fibers) are bundles of proteins found in extracellular matrix of connective tissue and produced by fibroblasts and smooth muscle cells in arteries. These fibers can stretch up to 1.5 times their length, and snap back to their original length when relaxed. Elastic fibers include elastin, elaunin and oxytalan. Elastic tissue is classified as 'connective tissue proper'. The elastic fiber is formed from the elastic microfibril and amorphous elastin. The microfibril scaffolds and organizes the deposition of amorphous elastin. Amorphous elastin forms from monomers of soluble tropoelastin which is insolubilized and crosslinked into amorphous elastin by lysyl oxidase. Lysyl oxidase reacts with specific lysine residues and by oxidative deamination generates reactive aldehydes and allysine. These reactive aldehydes and allysines can react with lysine and other allysine residues to crosslink and form desmosine, isodesmosine, and a number of other polyfunctional crosslinks that join surrounding elastin molecules to build an elastin matrix and elastic fiber. These unique crosslinks are responsible for elastin's elasticity. [WP,unvetted]." [Wikipedia:Elastic_fiber] subset: uberon_slim synonym: "elastic connective tissue" EXACT [] synonym: "textus connectivus elasticus" EXACT [] xref: FMA:20113 ! Elastic tissue xref: MA:0002853 ! elastic tissue xref: GAID:926 ! elastic tissue xref: MESH:A10.165.400 ! elastic tissue is_a: UBERON:0002384 ! connective tissue xref: SCTID:27197004 ! Elastic tissue xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Gray377.png [Term] id: UBERON:0001252 name: adventitia of ureter comment: This class was created automatically from a combination of ontologies synonym: "external adventitia of ureter" EXACT [] synonym: "ureter adventitia" EXACT [] synonym: "ureteral adventitia" EXACT [] xref: FMA:15892 ! Adventitia of ureter xref: MA:0002652 ! ureter adventitia xref: EMAPA:28114 ! adventitia of ureter intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0000056 ! ureter xref: SCTID:392273001 ! Entire adventitia of ureter xref: SCTID:47879001 ! Adventitia of ureter def: "An adventitia that is part of a ureter." [OBOL:automatic] relationship: part_of UBERON:0009916 {source="reference_0000032"} ! wall of ureter [Term] id: UBERON:0004797 name: blood vessel layer xref: MA:0002854 ! blood vessel layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: part_of UBERON:0001981 ! blood vessel def: "An organ component layer that is part of a blood vessel." [OBOL:automatic] [Term] id: UBERON:0004237 alt_id: UBERON:0010508 name: blood vessel smooth muscle def: "smooth muscle found within, and composing the majority of the wall of blood vessels." [Wikipedia:Vascular_smooth_muscle] comment: Function notes: Vascular smooth muscle contracts or relaxes to both change the volume of blood vessels and the local blood pressure, a mechanism that is responsible for the redistribution of the blood within the body to areas where it is needed (i.e. areas with temporarily enhanced oxygen consumption). Thus the main function of vascular smooth muscle tonus is to regulate the caliber of the blood vessels in the body. Excessive vasoconstriction leads to hypertension, while excessive vasodilation as in shock leads to hypotension. synonym: "blood vessel involuntary muscle" EXACT [OBOL:automatic] synonym: "blood vessel non-striated muscle" EXACT [OBOL:automatic] synonym: "blood vessel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of blood vessel" EXACT [OBOL:automatic] synonym: "non-striated muscle of blood vessel" EXACT [OBOL:automatic] synonym: "smooth muscle of blood vessel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of blood vessel" EXACT [OBOL:automatic] synonym: "vascular smooth muscle tissue" EXACT [] synonym: "vascular smooth muscle" EXACT [ZFA:0005321] xref: MA:0000710 ! blood vessel smooth muscle xref: BTO:0001431 ! vascular smooth muscle xref: MESH:A02.633.570.491 ! muscle smooth vascular xref: ZFA:0005321 ! vascular smooth muscle xref: ncithesaurus:Vascular_Smooth_Muscle_Tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001981 ! blood vessel xref: TAO:0005321 ! vascular smooth muscle xref: UMLS:C1519956 xref: CALOHA:TS-1107 ! Vascular smooth muscle [Term] id: UBERON:0002522 ! tunica media name: tunica media def: "The middle layer of an artery or vein. [WP,unvetted]." [Wikipedia:Tunica_media] comment: todo - check BTO subset: uberon_slim synonym: "tunica media vasorum" RELATED [BTO:0002011] xref: FMA:55590 ! Tunica media xref: MA:0002855 ! tunica media xref: ncithesaurus:Tunica_Media ! Tunica Media xref: GAID:170 ! tunica media xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/32/Illu_artery.jpg/200px-Illu_artery.jpg xref: MESH:A02.633.570.491.800 ! tunica media xref: BTO:0002011 ! tunica media vasorum is_a: UBERON:0004797 {source="MA"} ! blood vessel layer is_a: UBERON:0004237 {source="ncithesaurus"} ! vascular smooth muscle relationship: surrounded_by UBERON:0005734 ! tunica adventitia of blood vessel xref: SCTID:61695000 ! Tunica media vasorum synonym: "tunica media vasorum" RELATED LATIN [Wikipedia:Tunica_media] xref: http://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg xref: UMLS:C0162867 [Term] id: UBERON:0002523 ! tunica intima name: tunica intima def: "The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]." [Wikipedia:Tunica_intima, ISBN10:0073040584] subset: uberon_slim synonym: "tunica intima vasorum" RELATED [BTO:0002012] xref: FMA:55589 ! Tunica intima xref: MA:0002861 ! tunica intima xref: ncithesaurus:Tunica_Intima ! Tunica Intima xref: GAID:523 ! tunica intima xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/32/Illu_artery.jpg/200px-Illu_artery.jpg xref: MESH:A07.231.330.800 ! tunica intima xref: BTO:0002012 ! tunica intima vasorum is_a: UBERON:0004797 {source="MA"} ! blood vessel layer relationship: surrounded_by UBERON:0002522 {notes="check for exceptions, e.g. capillaries"} ! tunica media relationship: adjacent_to UBERON:0010161 {source="Kardong"} ! lumen of blood vessel relationship: has_part UBERON:0001986 ! endothelium xref: SCTID:8361002 ! Tunica intima xref: SCTID:87483006 ! Tunica intima of vessel xref: http://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg property_value: external_definition "The tunica intima (or just intima) is the innermost layer of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow. The inner coat (tunica intima) can be separated from the middle by a little maceration, or it may be stripped off in small pieces; but, on account of its friability, it cannot be separated as a complete membrane. It is a fine, transparent, colorless structure which is highly elastic, and, after death, is commonly corrugated into longitudinal wrinkles. The inner coat consists of: A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round or oval nuclei. This endothelium is brought into view most distinctly by staining with silver nitrate. A subendothelial layer, consisting of delicate connective tissue with branched cells lying in the interspaces of the tissue; in arteries of less than 2 mm. in diameter the subendothelial layer consists of a single stratum of stellate cells, and the connective tissue is only largely developed in vessels of a considerable size. An elastic or fenestrated layer, which consists of a membrane containing a net-work of elastic fibers, having principally a longitudinal direction, and in which, under the microscope, small elongated apertures or perforations may be seen, giving it a fenestrated appearance. It was therefore called by Henle the fenestrated membrane. This membrane forms the chief thickness of the inner coat, and can be separated into several layers, some of which present the appearance of a network of longitudinal elastic fibers, and others a more membranous character, marked by pale lines having a longitudinal direction. In minute arteries the fenestrated membrane is a very thin layer; but in the larger arteries, and especially in the aorta, it has a very considerable thickness. [WP,unvetted].[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Tunica_intima"} xref: UMLS:C0162864 [Term] id: UBERON:0005734 ! tunica adventitia of blood vessel name: tunica adventitia of blood vessel def: "The outermost layer of a blood vessel, composed mainly of fibrous tissue." [ISBN10:0073040584, Wikipedia:Tunica_externa_%28vessels%29] comment: TODO - note terminological problems. WP says tunica external layer of blood vessel. FMA says tunica externa = adventitia, and is FMA adventitia covers other kinds of vessels. Here we opt for a lengthier name that attempts to disambiguate. There is no precise FMA equivalent, as FMA has tunica externa of arteries, veins, genital ducts etc as siblings synonym: "tunica adventitia" EXACT [Wikipedia:Tunica_externa_%28vessels%29] synonym: "adventitia externa" EXACT [Wikipedia:Tunica_externa_%28vessels%29] synonym: "external coat" RELATED [Wikipedia:Tunica_externa_%28vessels%29] synonym: "tunica adventitia of vessel" EXACT [Wikipedia:Tunica_externa_%28vessels%29] is_a: UBERON:0005742 ! adventitia is_a: UBERON:0004797 {source="cjm"} ! blood vessel layer xref: ncithesaurus:Tunica_Adventitia ! Tunica Adventitia xref: SCTID:61066005 ! Tunica adventitia of vessel synonym: "tunica adventitia vasorum" RELATED LATIN [Wikipedia:Tunica_externa_%28vessels%29] synonym: "tunica externa vasorum" RELATED LATIN [Wikipedia:Tunica_externa_%28vessels%29] xref: http://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg property_value: external_definition "The outermost layer of a blood vessel, surrounding the tunica media. It is mainly composed of collagen. The collagen serves to anchor the blood vessel to nearby organs, giving it stability[Wikipedia:Tunica_externa_%28vessels%29]." xsd:string {source="Wikipedia:Tunica_externa_%28vessels%29"} xref: UMLS:C0225342 [Term] id: UBERON:0005742 ! adventitia name: adventitia def: "An outermost connective tissue covering of an organ, vessel, or other structure[WP]." [Wikipedia:Adventitia] subset: grouping_class synonym: "tunica externa" NARROW [FMA:45635] synonym: "tunica advetitia" NARROW [Wikipedia:Adventitia] xref: FMA:45635 ! Adventitia xref: SCTID:30180000 ! Tunica adventitia is_a: UBERON:0004923 ! organ component layer relationship: composed_primarily_of UBERON:0002384 ! connective tissue xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Illu_esophageal_layers.jpg [Term] id: UBERON:0006860 ! swim bladder name: swim bladder alt_id: UBERON:0008980 def: "A thin membranous, sometimes alveolated sac in the dorsal portion of the abdominal cavity. Contains a varying mixture of gases, not identical to the composition of air. May be one, two or three chambered. May be connected to the gut by a tube, the ductus pneumaticus (then called physostomous) or unconnected (then called physoclistous). May function as one or more of:- hydrostatic organ, sound producing organ, sound receptor, respiratory organ. Found in Actinopterygii. Often lacking in bottom fishes." [http://www.briancoad.com/Dictionary/S.htm] synonym: "gas bladder" EXACT [ZFA:0000076, http://www.briancoad.com/Dictionary/S.htm] xref: TAO:0000076 ! swim bladder xref: ZFA:0000076 ! swim bladder xref: BTO:0001607 ! swim bladder xref: EFO:0003483 ! swim bladder xref: SCTID:64748009 ! Gas bladder xref: BTO:0002148 ! gas bladder xref: VHOG:0000310 ! lung - swim bladder (also: UBERON:0002048 'lung') is_a: UBERON:0000489 ! cavitated compound organ relationship: develops_from UBERON:0006859 ! swim bladder bud relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: homologous_to UBERON:0002048 ! lung relationship: only_in_taxon NCBITaxon:7898 {source="Wikipedia"} ! Actinopterygii subset: organ_slim property_value: external_definition "Cavitated compound organ that is double-chambered, located in the coelom and used to maintain buoyancy and may function as an acoustic resonator.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000076", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "air bladder" RELATED [TAO:0000076] synonym: "swimbladder" EXACT [TAO:0000076] property_value: homology_notes "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata. (...) In actinopterygian fishes, apart from Cladistia, the ventral intestinal pocket migrates dorsally and becomes the swim-bladder, a mainly hydrostatical organ (reference 1); Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000310", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.210\, DOI:10.1371/journal.pone.0024019 Zheng W\, Wang Z\, Collins JE\, Andrews RM\, Stemple D\, Gong Z\, Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung. PLoS One (2011)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005737 name: swim bladder tunica externa def: "Multi-tissue structure that is the external layer of the swim bladder that is covered by the peritoneum, and made of elastic fibres and ichthyocol (short needles of collagen)." [http:www.briancoad.com/Dictionary/T.htm, ZFA:0001700] comment: the primary reason this term is manifest in uberon to disambiguate from a structure with the same/similar name synonym: "tunica externa" RELATED SENSU [ZFA:0001700] xref: TAO:0002245 ! tunica externa xref: ZFA:0001700 ! tunica externa is_a: UBERON:0005742 ! adventitia disjoint_from: UBERON:0005734 ! tunica adventitia of blood vessel relationship: part_of UBERON:0006860 ! swim bladder [Term] id: UBERON:0005738 name: swim bladder tunica interna def: "Multi-tissue structure that is the internal layer of the swim bladder and is comprised of thin endoderm and a smooth muscle layer called the muscularis mucosa with longitudinal and circular fibres with some collagen." [http:www.briancoad.com/Dictionary/T.htm] comment: the primary reason this term is manifest in uberon to disambiguate from a structure with the same/similar name synonym: "tunica interna" EXACT [ZFA:0001701] xref: TAO:0002246 ! tunica interna xref: ZFA:0001701 ! tunica interna is_a: UBERON:0005742 ! adventitia disjoint_from: UBERON:0002523 ! tunica intima relationship: part_of UBERON:0006860 ! swim bladder [Term] id: UBERON:0002524 ! mediastinal lymph node name: mediastinal lymph node def: "A lymph node that is part of a mediastinum. Each consists of several lymph node groups, especially along the trachea (5 groups), along the esophagus and between the lung and the diaphragm. In the mediastinal lymph nodes arises lymphatic ducts, which draines the lymph to the left subclavian vein (to the venous angle in the confluence of the subclavian and deep jugular veins). The mediastinal lymph nodes along the esophagus are in tight connection with the abdominal lymph nodes along the esophagus and the stomach. That fact facilitates spreading of tumors cells through these lymphatics in cases of cancers of the stomach and particularly of the esophagus. Through the mediastinum, the main lymphatic drainage from the abdominal organs goes via the thoracic duct (ductus thoracicus), which drains majority of the lymph from the abdomen to the above mentioned left venous angle." [OBOL:automatic, Wikipedia:Lymph_node#Lymph_nodes_of_the_thorax] synonym: "mediastinal node" EXACT [] xref: FMA:12774 ! Mediastinal lymph node xref: MA:0002877 ! mediastinal lymph node xref: ncithesaurus:Mediastinal_Lymph_Node ! Mediastinal Lymph Node xref: EFO:0001670 ! mediastinal lymph node is_a: UBERON:0007644 {source="FMA"} ! thoracic lymph node relationship: located_in UBERON:0003728 ! mediastinum xref: SCTID:181760002 ! Entire mediastinal lymph node xref: UMLS:C0588055 [Term] id: UBERON:0002525 name: brachial lymph node def: "the lymph nodes located along the brachial vein that receive drainage from most of the free upper limb and send efferent vessels to the central axillary lymph nodes." [MP:0005231, Wikipedia:Brachial_lymph_nodes] xref: FMA:44314 ! Brachial lymph node xref: MA:0002878 ! brachial lymph node xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/73/Gray607.png/200px-Gray607.png is_a: UBERON:0000029 ! lymph node xref: ncithesaurus:Brachial_Lymph_Node ! brachial lymph node synonym: "nodi lymphoidei brachiales" RELATED LATIN [Wikipedia:Brachial_lymph_nodes] xref: http://upload.wikimedia.org/wikipedia/commons/7/73/Gray607.png xref: UMLS:C0229840 [Term] id: UBERON:0002526 name: lumbar lymph node xref: FMA:84599 ! Lumbar lymph node xref: MA:0002879 ! lumbar lymph node is_a: UBERON:0002507 ! abdominal lymph node xref: SCTID:281412000 ! Entire lumbar lymph node [Term] id: UBERON:0002527 name: pancreatic lymph node def: "A lymph node that is part of a pancreas [Automatically generated definition]." [OBOL:automatic] synonym: "pancreatic node" EXACT [] synonym: "pyloric lymph node" RELATED [MA:0002881] synonym: "lymph node of pancreas" EXACT [OBOL:automatic] synonym: "pancreas lymph node" EXACT [OBOL:automatic] xref: FMA:16626 ! Pancreatic lymph node xref: MA:0002881 ! pancreatic lymph node is_a: UBERON:0002507 ! abdominal lymph node intersection_of: UBERON:0000029 ! lymph node intersection_of: part_of UBERON:0001264 ! pancreas xref: ncithesaurus:Pancreatic_Lymph_Node ! Pancreatic Lymph Node xref: SCTID:276170003 ! Entire pancreatic lymph node xref: UMLS:C0229783 [Term] id: UBERON:0002528 name: sacral lymph node synonym: "sacral node" EXACT [] xref: FMA:16655 ! Sacral lymph node xref: MA:0002883 ! sacral lymph node is_a: UBERON:0000029 ! lymph node xref: ncithesaurus:Sacral_Lymph_Node ! Sacral Lymph Node xref: SCTID:279797001 ! Entire sacral lymph node xref: UMLS:C0229827 [Term] id: UBERON:0010538 ! limb/fin segment name: limb/fin segment intersection_of: UBERON:0010758 ! appendage segment intersection_of: part_of UBERON:0004708 ! limb/fin relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata disjoint_from: UBERON:0010912 ! subdivision of skeleton disjoint_from: UBERON:0001474 ! bone element def: "An appendage segment that is part of a limb/fin." [OBOL:automatic] [Term] id: UBERON:0002529 name: limb segment def: "A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles." [UBERON:cjm] comment: note FMA has both limb segment and free limb segment, the former includes the girdles. Note that MA uses the term more generally and includes A,S,Z,S+Z(arm/leg), whereas FMA is just A,S,Z synonym: "extremity part" RELATED [] synonym: "limb region" EXACT [] synonym: "region of limb" EXACT [] synonym: "segment of limb" EXACT [] synonym: "subdivision of limb" EXACT [] synonym: "free limb segment" EXACT [FMA:241863] xref: FMA:241863 ! free limb segment xref: MA:0002889 ! limb segment xref: ncithesaurus:Extremity_Part ! extremity part intersection_of: UBERON:0010758 ! appendage segment intersection_of: part_of UBERON:0002101 ! limb disjoint_from: UBERON:0010912 ! subdivision of skeleton relationship: existence_starts_during UBERON:0000068 ! embryo stage relationship: existence_ends_during UBERON:0000066 ! fully formed stage xref: UMLS:C1268195 [Term] id: UBERON:0008784 name: lower limb segment synonym: "free lower limb subdivision" EXACT [FMA:24877] synonym: "segment of free lower limb" EXACT [FMA:24877] synonym: "subdivision of free lower limb" EXACT [FMA:24877] synonym: "free lower limb segment" EXACT [FMA:24877] intersection_of: UBERON:0002529 ! limb segment intersection_of: part_of UBERON:0002103 ! hindlimb xref: FMA:24877 ! free lower limb segment def: "A limb segment that is part of a hindlimb." [OBOL:automatic] [Term] id: UBERON:0008785 name: upper limb segment synonym: "free upper limb subdivision" EXACT [FMA:24876] synonym: "segment of free upper limb" EXACT [FMA:24876] synonym: "subdivision of free upper limb" EXACT [FMA:24876] synonym: "free upper limb segment" EXACT [FMA:24876] intersection_of: UBERON:0002529 ! limb segment intersection_of: part_of UBERON:0002102 ! forelimb xref: FMA:24876 ! free upper limb segment def: "A limb segment that is part of a forelimb." [OBOL:automatic] [Term] id: UBERON:0002530 name: gland alt_id: UBERON:MIAA_0000021 def: "A gland is an organ in an animal's body that synthesizes a substance for release such as hormones or breast milk, often into the bloodstream (endocrine gland) or into cavities inside the body or its outer surface (exocrine gland). A gland is an organ specialised for secretion[GO]." [Wikipedia:Gland] subset: uberon_slim synonym: "Druese" RELATED [BTO:0000522] synonym: "glandula" RELATED [BTO:0000522] xref: AAO:0000212 ! glands xref: BTO:0000522 xref: EFO:0000797 ! gland xref: EHDAA:2161 ! gland xref: EHDAA:4475 ! gland (also: UBERON:0003296 'gland of diencephalon') xref: EHDAA:6522 ! gland (also: UBERON:0003297 'gland of integumental system') xref: galen:Gland xref: HAO:0000375 ! gland xref: MAT:0000021 ! gland xref: MIAA:0000021 ! gland xref: FMA:86294 ! Gland xref: ncithesaurus:Gland ! Gland xref: OpenCyc:Mx4rwP3vyJwpEbGdrcN5Y29ycA ! gland xref: EHDAA2:0003096 ! gland xref: AEO:0000096 ! gland xref: EMAPA:18425 ! gland of organ system xref: WikipediaCategory:Glands is_a: UBERON:0000062 ! organ relationship: capable_of GO:0046903 ! secretion relationship: secretes UBERON:0000463 ! portion of organism substance xref: SCTID:134358001 ! Gland xref: FBbt:00100317 ! gland synonym: "glandula" RELATED LATIN [Wikipedia:Gland] xref: http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray1026.png property_value: has_relational_adjective "glandular" xsd:string xref: UMLS:C1285092 [Term] id: UBERON:0006799 ! glandular epithelium name: glandular epithelium def: "Epithelium composed of secretory cells." [Online_Medical_Dictionary:http://cancerweb.ncl.ac.uk/] comment: Editor notes: consider splitting epithelium from epithelial tissue xref: BTO:0002991 ! glandular epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: has_part CL:0000150 ! glandular epithelial cell relationship: secretes UBERON:0000463 ! portion of organism substance xref: ncithesaurus:Glandular_Epithelium ! Glandular Epithelium xref: ncithesaurus:Glandular_Epithelial_Tissue ! Glandular Epithelial Tissue xref: UMLS:C1708242 xref: UMLS:C0682578 [Term] id: UBERON:0011952 ! non-glandular epithelium name: non-glandular epithelium is_a: UBERON:0000483 ! epithelium disjoint_from: UBERON:0006799 ! glandular epithelium [Term] id: UBERON:0006929 name: glandular columnar epithelium def: "Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA]" [FMA:64800] xref: FMA:64800 ! glandular columnar epithelium is_a: UBERON:0000485 ! simple columnar epithelium relationship: has_part CL:0000150 ! glandular epithelial cell xref: ncithesaurus:Columnar_Epithelium ! columnar epithelium xref: UMLS:C0225337 [Term] id: UBERON:0010498 name: pseudostratified columnar epithelium def: "A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels." [http://medical-dictionary.thefreedictionary.com/pseudostratified+epithelium, Wikipedia:Pseudostratified_columnar_epithelium] comment: AO notes: glandular in NCIT; we consider the two NCIT terms synonymous. Function notes: Pseudostratified epithelia function in secretion or absorption. If a specimen looks stratified but has cilia, then it is a pseudostratified ciliated epithelium, since stratified epithelia do not have cilia. is_a: UBERON:0000485 {source="FMA"} ! simple columnar epithelium xref: FMA:45572 ! pseudostratified columnar epithelium xref: ncithesaurus:Pseudostratified_Columnar_Epithelium ! pseudostratified columnar epithelium xref: ncithesaurus:Pseudostratified_Epithelium ! pseudostratified epithelium xref: UMLS:C0836138 xref: UMLS:C1514590 [Term] id: UBERON:0010499 name: pseudostratified ciliated columnar epithelium def: "Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile." [NCIT:NCIT] synonym: "epithelium pseudostratificatum columnare ciliatum (trachea et bronchi)" EXACT [FMA:13146] intersection_of: UBERON:0010498 ! pseudostratified columnar epithelium intersection_of: has_part CL:0000067 ! ciliated epithelial cell disjoint_from: UBERON:0010501 ! pseudostratified smooth columnar epithelium xref: FMA:13146 ! pseudostratified ciliated columnar epithelium xref: ncithesaurus:Pseudostratified_Columnar_Ciliated_Epithelium ! pseudostratified columnar ciliated epithelium xref: UMLS:C0506992 [Term] id: UBERON:0010501 name: pseudostratified smooth columnar epithelium synonym: "non-ciliated pseudostratified columnar epithelia" RELATED [] is_a: UBERON:0010498 {source="FMA"} ! pseudostratified columnar epithelium xref: FMA:72059 ! pseudostratified smooth columnar epithelium [Term] id: UBERON:0006930 name: glandular cuboidal epithelium xref: FMA:66809 ! glandular cuboidal epithelium is_a: UBERON:0000484 ! simple cuboidal epithelium relationship: has_part CL:0000150 ! glandular epithelial cell [Term] id: UBERON:0005732 ! limb/fin field name: limb/fin field def: "A ring of cells capable of forming a limb or paired fin[Gilbert,modified]." [ISBN:9780878932504] comment: Editor notes: we represent the field as being a part of the LPM (consistent with ZFA, Gilbert). As a consequence, the relationship between limb bud (with is ectoderm+mesenchyme) stands in a weaker has_developmental_contribution_from relation to the field - TODO implement this. synonym: "limb/fin field of lateral plate mesoderm" EXACT [] intersection_of: UBERON:0001048 ! primordium intersection_of: developmentally_contributes_to UBERON:0004357 ! limb/fin bud relationship: part_of UBERON:0003081 {source="ZFA-inferred", source="ISBN:9780878932504"} ! lateral plate mesoderm [Term] id: UBERON:0005729 name: pectoral appendage field synonym: "pectoral fin field" NARROW SENSU [ZFA:0001453] synonym: "pectoral appendage field of lateral plate mesoderm" EXACT [] xref: ZFA:0001453 ! pectoral fin field intersection_of: UBERON:0005732 ! limb/fin field intersection_of: develops_into UBERON:0003413 ! pectoral appendage bud mesenchyme xref: TAO:0001453 ! pectoral fin field property_value: external_definition "Embryonic region that develops into the pectoral fin bud.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001453", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A limb/fin field that develops_into a pectoral appendage bud mesenchyme." [OBOL:automatic] [Term] id: UBERON:0005730 name: pelvic appendage field synonym: "pelvic fin field" NARROW SENSU [ZFA:0001454] synonym: "pelvic appendage field of lateral plate mesoderm" EXACT [] xref: ZFA:0001454 ! pelvic fin field intersection_of: UBERON:0005732 ! limb/fin field intersection_of: develops_into UBERON:0003412 ! pelvic appendage bud mesenchyme xref: TAO:0001454 ! pelvic fin field property_value: external_definition "Embryonic region that develops into the pelvic fin bud.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001454", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A limb/fin field that develops_into a pelvic appendage bud mesenchyme." [OBOL:automatic] [Term] id: UBERON:0005731 ! fin field name: fin field synonym: "fin field of lateral plate mesoderm" EXACT [] intersection_of: UBERON:0005732 ! limb/fin field intersection_of: developmentally_contributes_to UBERON:0002531 ! fin bud def: "A limb/fin field that developmentally_contributes_to a paired fin bud." [OBOL:automatic] [Term] id: UBERON:0005733 ! limb field name: limb field def: "A ring of cells capable of forming a limb." [ISBN:9780878932504] synonym: "limb field of lateral plate mesoderm" EXACT [] comment: the central portion of the limb field gives rise to the limb proper. mesenchyme cells proliferate from from the somatic layer of limb field lateral plate mesoderm (limb skeletal precursors) and from the somites (limb muscle precursors) . these mesenchymal cells accumulate under the ectedermal tissue to make a limb bud. // The lateral plate mesoderm in the limb field is also special in that it will induce myoblasts to migrate out from the somites and enter the limb bud. No other region of the lateral plate mesoderm will do that (Hayashi and Ozawa 1995) intersection_of: UBERON:0005732 ! limb/fin field intersection_of: developmentally_contributes_to UBERON:0004347 ! limb bud [Term] id: UBERON:0004357 ! limb/fin bud name: limb/fin bud def: "An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." [MP:0005650, UBERON:cjm, ISBN:9780878932504] comment: Genes: In limb buds of chick and mouse, Shh expression is activated as soon as there is a morphological bud, whereas in S. canicula fin buds, consistent with reported data in other cartilaginous fishes, Shh is transcribed late in fin development[PMID:17187056] synonym: "paired appendage bud" EXACT [] xref: VHOG:0001258 ! limb/fin bud is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0000922 ! embryo relationship: has_part UBERON:0004356 ! apical ectodermal ridge relationship: develops_into UBERON:0004708 ! limb/fin relationship: has_developmental_contribution_from UBERON:0005732 ! limb/fin field synonym: "limb - fin bud" EXACT [VHOG:0001258] property_value: homology_notes "The tetrapod limb is derived from a posterior part of the fin endoskeleton of elasmobranchs and basal bony fish, the so-called metapterygium, a series of endoskeletal elements that is the first to form in the developing paired fins. (...) In addition, there is an independent endoskeletal element called the protopterygium that develops anterior to the metapterygium in many basal fishes (e.g., the bichir and sturgeon). Teleosts have lost the metapterygium whereas the sarcopterygians, on the other hand, have lost the protopterygium. Sarcopterygians thus develop all their endoskeletal structures from the metapterygium and consequently the tetrapod limb skeleton is derived from the metapterygium.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001258", ontology="VHOG", source="DOI:10.1002/jez.1100 Wagner GP\, Chiu C\, The tetrapod limb: A hypothesis on its origin. J Exp Zool (Mol Dev Evol) (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005419 ! pectoral appendage bud name: pectoral appendage bud def: "A limb bud that develops into a forelimb or pectoral fin." [OBOL:automatic] comment: at this time we have no need to name a more specific 'pectoral fin bud' class, but we may in future xref: ZFA:0000141 ! pectoral fin bud xref: VHOG:0001754 ! forelimb - pectoral fin bud xref: VHOG_RETIRED:0001259 ! pectoral appendage bud xref: EFO:0003430 ! pectoral fin bud intersection_of: UBERON:0004357 ! limb/fin bud intersection_of: develops_into UBERON:0004710 ! pectoral appendage relationship: part_of UBERON:0000153 ! anterior region of body relationship: has_developmental_contribution_from UBERON:0005729 ! pectoral appendage field xref: TAO:0000141 ! pectoral fin bud property_value: external_definition "Fin bud that develops into the pectoral fin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000141", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "forelimb - pectoral fin bud" EXACT [VHOG:0001754] synonym: "pectoral fin bud" RELATED [TAO:0000141] synonym: "pectoral fin buds" RELATED PLURAL [TAO:0000141] property_value: homology_notes "While the skeletons of teleost pectoral fins and tetrapod forelimbs are homologous at the level of endoskeletal radials, teleosts and tetrapods do not share homologous skeletal elements at the level of 'individuated' pro-, meso-, and metapterygia. Among osteichthyans, only basal actinopterygians retain the full complement of elements present in non-osteichthyan gnathostomes.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001754", ontology="VHOG", source="DOI:10.1002/jmor.10264 Davis MC\, Shubin NH\, Force A\, Pectoral fin and girdle development in the basal actinopterygians Polyodon spathula and Acipenser transmontanus. Journal of Morphology (2004)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005420 ! pelvic appendage bud name: pelvic appendage bud def: "A limb bud that develops into a hindlimb or pelvic fin." [OBOL:automatic] comment: at this time we have no need to name a more specific 'pelvic fin bud' class, but we may in future synonym: "hindlimb/pelvic fin bud" EXACT [VHOG:0001260] xref: VHOG:0001260 ! hindlimb/pelvic fin bud xref: ZFA:0001384 ! pelvic fin bud xref: EFO:0003469 ! pelvic fin bud intersection_of: UBERON:0004357 ! limb/fin bud intersection_of: develops_into UBERON:0004709 ! pelvic appendage intersection_of: part_of UBERON:0000154 ! posterior region of body relationship: has_developmental_contribution_from UBERON:0005730 ! pelvic appendage field relationship: never_in_taxon NCBITaxon:31033 {source="PMID:15893975"} ! Takifugu rubripes xref: TAO:0001384 ! pelvic fin bud property_value: external_definition "Fin bud that develops into the pelvic fin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001384", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "pelvic fin bud" RELATED [TAO:0001384] property_value: homology_notes "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {external_class="VHOG:0001260", ontology="VHOG", source="ISBN:978-0198540472 Janvier P\, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002531 name: paired fin bud def: "An outgrowth on the lateral trunk of the embryo that develops into a paired fin. The fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." [MP:0005650, UBERON:cjm, ISBN:9780878932504] synonym: "fin bud" EXACT [ZFA:0001383] xref: MAT:0000062 ! fin bud xref: MIAA:0000062 ! fin bud xref: TAO:0001383 ! fin bud xref: ZFA:0001383 ! fin bud xref: EFO:0003468 ! fin bud xref: VSAO:0000179 ! fin bud intersection_of: UBERON:0004357 ! limb/fin bud intersection_of: develops_into UBERON:0002534 ! paired fin relationship: has_developmental_contribution_from UBERON:0005731 ! fin field property_value: external_definition "Embryonic surface structure that develops into a paired fin.[ZFA]" xsd:string {ontology="ZFA", external_class="ZFA:0001383", date_retrieved="2012-08-31", source="ZFIN:curator"} synonym: "fin buds" EXACT PLURAL [VSAO:0000179] [Term] id: UBERON:0004347 name: limb bud def: "An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." [MP:0005650, UBERON:cjm, ISBN:9780878932504, Wikipedia:Limb_bud] comment: induced_by Fgf10, capable of initiating limb forming interactions between endoderm and mesoderm synonym: "limb buds" EXACT PLURAL [] synonym: "limbbud" EXACT [GO:0060174] xref: ncithesaurus:Limb_Bud ! Limb Bud xref: BTO:0001640 ! limb bud xref: GAID:1307 ! limb bud xref: XAO:0003161 ! limb bud xref: MESH:A16.254.462 ! limb bud xref: AAO:0010375 ! limb bud is_a: UBERON:0004357 ! limb/fin bud relationship: develops_into UBERON:0002101 ! limb relationship: induced_by UBERON:0003081 {source="ISBN:9780878932504"} ! lateral plate mesoderm relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: has_developmental_contribution_from UBERON:0005733 ! limb field synonym: "gemmae membrorum" RELATED LATIN [Wikipedia:Limb_bud] property_value: external_definition "Early outgrowth of presumptive limb.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010375", date_retrieved="2012-06-20", source="AAO:EJS"} xref: UMLS:C0282505 [Term] id: UBERON:0012300 name: limb paddle def: "A transient developing limb structure that develops from the limb bud; it is a dorsoventral flattening of the limb bud structure and develops into the foot plate" [MP:0011685] is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0004347 ! limb bud [Term] id: UBERON:0005417 name: forelimb bud def: "A limb bud that develops into a forelimb." [OBOL:automatic] synonym: "wing bud" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] comment: Genes: Tbx5 specifies forelimbs. Wnt2b restricts Fgf10 in chick // In tetrapods, the position of the forelimb is associated with the anterior expression border of Hoxc6 in the paraxial mesoderm (Burke et al., 1995) synonym: "upper limb bud" EXACT [RETIRED_EHDAA2:0003198] synonym: "limb bud - forelimb" EXACT [MIAA:0000065] synonym: "arm bud" RELATED [] xref: XAO:0003065 ! forelimb bud xref: RETIRED_EHDAA2:0003198 ! upper limb bud xref: EHDAA:1699 ! upper limb bud xref: EMAPA:16406 ! forelimb bud xref: MIAA:0000065 ! limb bud - forelimb xref: XAO:0003065 ! forelimb bud xref: BTO:0001645 ! wing bud intersection_of: UBERON:0004347 ! limb bud intersection_of: develops_into UBERON:0002102 ! forelimb relationship: part_of UBERON:0000153 ! anterior region of body xref: AAO:0010381 ! forelimb bud xref: SCTID:346062002 ! anterior limb bud synonym: "anterior limb bud" EXACT [SCTID:346062002] [Term] id: UBERON:0005418 name: hindlimb bud def: "A limb bud that develops into a hindlimb." [OBOL:automatic] comment: Genes: Tbx4 specifies hindlimbs. Wnt8c restricts Fgf10 in chick. synonym: "hind limb bud" EXACT [XAO:0003066] synonym: "leg bud" RELATED [] synonym: "limb bud - hindlimb" RELATED [] xref: XAO:0003066 ! hind limb bud xref: RETIRED_EHDAA2:0003197 ! lower limb bud xref: EHDAA:2358 ! lower limb bud xref: EMAPA:16779 ! hindlimb bud xref: MIAA:0000256 ! limb bud - hindlimb intersection_of: UBERON:0004347 ! limb bud intersection_of: develops_into UBERON:0002103 ! hindlimb intersection_of: part_of UBERON:0000154 ! posterior region of body xref: AAO:0010382 ! hind limb bud xref: SCTID:346164003 ! posterior limb bud synonym: "posterior limb bud" EXACT [SCTID:346164003] property_value: external_definition "The bilateral thickening of the ectoderm in the region of the first noticeable at NF stage 47, and innervated by NF stage 51. The hind limb buds develop before the forelimb buds.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010382", date_retrieved="2012-06-20", source="XAO:curator"} [Term] id: UBERON:0003371 name: pelvic appendage bud ectoderm alt_id: UBERON:0005232 synonym: "leg ectoderm" RELATED [OBOL:automatic] synonym: "pelvic fin bud ectoderm" NARROW SENSU [] synonym: "hindlimb bud ectoderm" NARROW SENSU [] synonym: "lower limb bud ectoderm" NARROW SENSU [EHDAA2:0001034] synonym: "hindlimb ectoderm" NARROW SENSU [VHOG:0001048] synonym: "hindlimb ectoderm" EXACT [VHOG:0001048] xref: EMAPA:17254 ! ectoderm of leg of hindlimb bud xref: VHOG:0001048 ! hindlimb ectoderm xref: EHDAA2:0001034 ! lower limb bud ectoderm intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: surrounds UBERON:0005420 ! pelvic appendage bud relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0005420 ! pelvic appendage bud def: "An unilaminar epithelium that surrounds a pelvic appendage bud." [OBOL:automatic] [Term] id: UBERON:0003372 name: pectoral appendage bud ectoderm alt_id: UBERON:0005663 alt_id: UBERON:0005231 synonym: "pectoral fin bud ectoderm" NARROW SENSU [] synonym: "forelimb bud ectoderm" NARROW SENSU [] synonym: "arm ectoderm" RELATED [OBOL:automatic] synonym: "upper limb bud ectoderm" NARROW SENSU [EHDAA2:0002134] synonym: "forelimb ectoderm" NARROW SENSU [VHOG:0001047] synonym: "wing ectoderm" NARROW SENSU [Geisha:syn, NCBITaxon:8782] xref: EMAPA:17243 ! ectoderm of arm of forelimb bud xref: EHDAA2:0002134 ! upper limb bud ectoderm xref: VHOG:0001047 ! forelimb ectoderm intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: surrounds UBERON:0005419 ! pectoral appendage bud relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0005419 ! pectoral appendage bud def: "An unilaminar epithelium that surrounds a pectoral appendage bud." [OBOL:automatic] [Term] id: UBERON:0004356 ! apical ectodermal ridge name: apical ectodermal ridge def: "multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. " [MP:0001676, Wikipedia:Apical_ectodermal_ridge] comment: Usage notes: note that media, dorsal fins etc have AERs. Taxon/development notes: The AER of tetrapods regresses after specification of skeletal progenitors, the AER of teleosts form an elongating fin fold[PMID:20574421]. Function notes: maintaining mesenchyme in plastic proliferating state; maintaining expression of A-P axis genes; interacting with D-V proteins. Genes: AER induced by Fgf10 in mesenchyme. AER secretes Fgf8, which stimulates mitosis in the mesenchyme causing Fgf10 production - positive feedback loop synonym: "AER" RELATED [MP:0001676] xref: ZFA:0001702 ! apical ectodermal ridge xref: AAO:0010760 ! apical ectodermal ridge xref: XAO:0004121 ! apical ectodermal ridge xref: EMAPA:32744 ! apical ectodermal ridge xref: ncithesaurus:Apical_Ectodermal_Ridge ! Apical Ectodermal Ridge is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004357 ! limb/fin bud relationship: part_of UBERON:0000924 ! ectoderm relationship: induced_by UBERON:0003104 ! mesenchyme relationship: capable_of GO:0010464 ! regulation of mesenchymal cell proliferation relationship: capable_of GO:0061037 ! negative regulation of cartilage development relationship: secretes PR:000007499 ! fibroblast growth factor 8 xref: TAO:0002146 ! apical ectodermal ridge synonym: "crista ectodermalis apicalis" RELATED LATIN [Wikipedia:Apical_ectodermal_ridge] xref: http://upload.wikimedia.org/wikipedia/commons/5/56/Limbbuddiagram.jpg property_value: external_definition "Distal ectodermal thickening which forms along the anterior-posterior limb axis. Signaling from this region influences proximal-distal patterning of the limb. Structure is missing in some lineages (salamanders, Eleutherodactylus coqui) however morphologically their indistinct distal ectoderm may still be involved in signaling.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010760", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Proliferative region that is part of the developing fin fold or fin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002146", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass proliferative region (TAO:0000098)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002146", date_retrieved="2012-08-14"} xref: UMLS:C1516037 [Term] id: UBERON:0005421 name: pectoral appendage apical ectodermal ridge subset: vertebrate_core synonym: "apical ectodermal ridge pectoral fin bud" NARROW [ZFA:0000085] synonym: "upper limb bud apical ectodermal ridge" NARROW [EHDAA2:0000138] synonym: "apical ectodermal ridge forelimb" NARROW [VHOG:0001064] synonym: "AER forelimb" NARROW [VHOG:0001064] synonym: "wing AER" NARROW SENSU [Giesha:syn] synonym: "wing apical ectodermal ridge" NARROW SENSU [] xref: VHOG:0001064 ! apical ectodermal ridge forelimb xref: EHDAA2:0000138 ! upper limb bud apical ectodermal ridge xref: ZFA:0000085 ! apical ectodermal ridge pectoral fin bud xref: EMAPA:16778 ! apical ectodermal ridge of ectoderm of forelimb bud xref: EFO:0003487 ! apical ectodermal ridge pectoral fin bud intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0005419 ! pectoral appendage bud relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm xref: TAO:0000085 ! apical ectodermal ridge pectoral fin bud xref: TAO:0000736 ! apical ectodermal ridge pectoral fin property_value: external_definition "Apical ectodermal ridge that is part of the pectoral fin bud.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000085", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "aer pectoral fin" RELATED [TAO:0000085] synonym: "apical ectodermal ridge pectoral fin" RELATED [TAO:0000085] synonym: "apical fold pectoral fin" RELATED [TAO:0000085] property_value: external_definition "An ectodermal thickening at the end of the forelimb bud in the developing embryo. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001064", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/apical+ectodermal+ridge", source="http://bgee.unil.ch/"} property_value: homology_notes "Pectoral and pelvic fins are homologous to the tetrapod fore and hindlimb, respectively. (...) The zebrafish AER [apical ectodermal ridge] is an apical ectodermal thickening at the distal tip of the fin bud and consists of wedge-shaped cells of the basal stratum. The AER is observed only transiently, and from 36 hpf onwards the cells of this region form the apical fold (AF), which consists of a dorsal and a ventral layer of cylindrically-shaped ectodermal cells extending from the anterior to the posterior fin margin. Despite the change in shape, the AF still carries out the same functions as the AER. Indeed, although the AER receives its name from its characteristic shape, being composed of a pseudostratified ectoderm in the chicken and a polystratified ectoderm in the mouse, this independence of AER morphology from its function is also observed in tetrapods. The AF also expresses similar molecular markers to the tetrapod AER, suggesting that it fulfills similar functions in the fin as the AER does in tetrapod limbs.[well established][VHOG]" xsd:string {external_class="VHOG:0001064", ontology="VHOG", source="DOI:10.1111/j.1440-169X.2007.00942.x", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An apical ectodermal ridge that is part of a pectoral appendage bud." [OBOL:automatic] [Term] id: UBERON:0005422 ! pelvic appendage apical ectodermal ridge name: pelvic appendage apical ectodermal ridge subset: vertebrate_core synonym: "lower lmb bud apical ectodermal ridge" NARROW [EHDAA2:0003194] synonym: "apical ectodermal ridge hindlimb" NARROW [VHOG:0001066] synonym: "AER hindlimb" RELATED [VHOG:0001066] synonym: "leg AER" RELATED [] xref: VHOG:0001066 ! apical ectodermal ridge hindlimb xref: EHDAA2:0003194 ! lower limb bud apical ectodermal ridge xref: ZFA:0001385 ! apical ectodermal ridge pelvic fin bud xref: EMAPA:16892 ! apical ectodermal ridge of ectoderm of hindlimb bud intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0005420 ! pelvic appendage bud relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm xref: TAO:0001385 ! apical ectodermal ridge pelvic fin bud property_value: external_definition "Apical ectodermal ridge that is part of the pelvic fin bud.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001385", date_retrieved="2012-08-14", source="ZIFIN:curator"} synonym: "apical ectodermal ridge hind limb" NARROW [VHOG:0001066] synonym: "apical ectodermal ridge pelvic fin bud" RELATED [TAO:0001385] property_value: external_definition "An ectodermal thickening at the end of the hindlimb bud in the developing embryo. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001066", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/apical+ectodermal+ridge", source="http://bgee.unil.ch/"} property_value: homology_notes "Pectoral and pelvic fins are homologous to the tetrapod fore and hindlimb, respectively. (...) The zebrafish AER [apical ectodermal ridge] is an apical ectodermal thickening at the distal tip of the fin bud and consists of wedge-shaped cells of the basal stratum. The AER is observed only transiently, and from 36 hpf onwards the cells of this region form the apical fold (AF), which consists of a dorsal and a ventral layer of cylindrically-shaped ectodermal cells extending from the anterior to the posterior fin margin. Despite the change in shape, the AF still carries out the same functions as the AER. Indeed, although the AER receives its name from its characteristic shape, being composed of a pseudostratified ectoderm in the chicken and a polystratified ectoderm in the mouse, this independence of AER morphology from its function is also observed in tetrapods. The AF also expresses similar molecular markers to the tetrapod AER, suggesting that it fulfills similar functions in the fin as the AER does in tetrapod limbs.[well established][VHOG]" xsd:string {external_class="VHOG:0001066", ontology="VHOG", source="DOI:10.1111/j.1440-169X.2007.00942.x", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: EFO:0003681 ! apical ectodermal ridge pelvic fin bud def: "An apical ectodermal ridge that is part of a pelvic appendage bud." [OBOL:automatic] [Term] id: UBERON:0010328 name: limb bud mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004347 ! limb bud def: "Mesenchyme that is part of a limb bud." [OBOL:automatic] [Term] id: UBERON:0010329 name: limb/fin bud mesenchyme relationship: develops_from UBERON:0010377 {source="EHDAA2-abduced"} ! mesenchyme from somatopleure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004357 ! limb/fin bud def: "Mesenchyme that is part of a limb/fin bud." [OBOL:automatic] [Term] id: UBERON:0003412 name: pelvic appendage bud mesenchyme synonym: "leg mesenchyme" EXACT [OBOL:automatic] synonym: "lower limb bud mesenchyme" EXACT [EHDAA2:0001035] synonym: "mesoderm pelvic fin bud" NARROW SENSU [ZFA:0001386] synonym: "pelvic fin bud mesenchyme" NARROW SENSU [] synonym: "lower limb bud mesenchyme" EXACT [EHDAA2:0001035] xref: EMAPA:17255 ! mesenchyme of leg of hindlimb bud xref: EHDAA2:0001035 ! lower limb bud mesenchyme xref: ZFA:0001386 ! mesoderm pelvic fin bud intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005420 ! pelvic appendage bud relationship: develops_from UBERON:0005730 ! pelvic appendage field xref: TAO:0001386 ! mesoderm pelvic fin bud property_value: external_definition "Mesoderm part of pelvic fin bud.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001386", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "Mesenchyme that is part of a pelvic appendage bud." [OBOL:automatic] [Term] id: UBERON:0003413 name: pectoral appendage bud mesenchyme alt_id: UBERON:0005703 synonym: "arm mesenchyme" NARROW [OBOL:automatic] synonym: "wing mesenchyme" NARROW [OBOL:automatic] synonym: "upper limb bud mesenchyme" NARROW [EHDAA2:0002135] synonym: "mesoderm pectoral fin bud" NARROW SENSU [ZFA:0000789] synonym: "pectoral fin bud mesenchyme" NARROW SENSU [] synonym: "upper limb bud mesenchyme" NARROW [EHDAA2:0002135] xref: EMAPA:17244 ! mesenchyme of arm of forelimb bud xref: EHDAA2:0002135 ! upper limb bud mesenchyme xref: EHDAA:1703 ! mesenchyme of upper limb bud xref: ZFA:0000789 ! mesoderm pectoral fin bud intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005419 ! pectoral appendage bud relationship: develops_from UBERON:0005729 ! pectoral appendage field xref: TAO:0000789 ! mesoderm pectoral fin bud property_value: external_definition "Mesoderm that is part of the pectoral fin bud.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000789", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "Mesenchyme that is part of a pectoral appendage bud." [OBOL:automatic] [Term] id: UBERON:0005414 name: zone of polarizing activity def: "an area of mesenchyme that contains signals which instruct the developing limb or fin bud to form along the anterior/posterior axis[WP,cjm]." [Wikipedia:Zone_of_polarizing_activity] comment: WP definition generalized to cover limb/fin synonym: "ZPA" EXACT [ZFA:0001451] is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0010329 ! limb/fin bud mesenchyme xref: AAO:0010763 ! zone of polarizing activity synonym: "zona activitatis polarisantis" RELATED LATIN [Wikipedia:Zone_of_polarizing_activity] xref: http://upload.wikimedia.org/wikipedia/commons/5/56/Limbbuddiagram.jpg property_value: external_definition "Morphologically indistinct signaling region found in the posterior portion of the limb bud. Associated with anterior-posterior patterning of the digits.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010763", date_retrieved="2012-06-20", source="AAO:EJS"} [Term] id: UBERON:0005415 name: zone of polarizing activity of pectoral appendage xref: ZFA:0001451 ! zone of polarizing activity pectoral fin bud synonym: "anterior ZPA" EXACT [] synonym: "fore ZPA" EXACT [] synonym: "pectoral ZPA" EXACT [] synonym: "zone of polarizing activity pectoral fin bud" NARROW [ZFA:0001451] intersection_of: UBERON:0005414 ! zone of polarizing activity intersection_of: part_of UBERON:0003413 ! pectoral appendage bud mesenchyme xref: TAO:0001451 ! zone of polarizing activity pectoral fin bud property_value: external_definition "A small group of mesodermal cells located at the posterior margin of the developing fin bud. the ZPA is thought to produce retinoic acid and thereby provides positional information to the developing bud. Gibert et al., 2006.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001451", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A zone of polarizing activity that is part of a pectoral appendage bud mesenchyme." [OBOL:automatic] [Term] id: UBERON:0005416 name: zone of polarizing activity of pelvic appendage xref: ZFA:0001452 ! zone of polarizing activity pelvic fin bud synonym: "posterior ZPA" EXACT [] synonym: "hind ZPA" EXACT [] synonym: "pelvic ZPA" EXACT [] synonym: "zone of polarizing activity pelvic fin bud" NARROW [ZFA:0001452] intersection_of: UBERON:0005414 ! zone of polarizing activity intersection_of: part_of UBERON:0003412 ! pelvic appendage bud mesenchyme xref: TAO:0001452 ! zone of polarizing activity pelvic fin bud property_value: external_definition "A small group of mesodermal cells located at the posterior margin of the developing fin bud. The ZPA is thought to produce retinoic acid and thereby provides positional information to the developing bud. Gibert et al., 2006.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001452", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A zone of polarizing activity that is part of a pelvic appendage bud mesenchyme." [OBOL:automatic] [Term] id: UBERON:0002533 ! tail bud name: tail bud def: "The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node." [BTO:0001445] comment: Editor notes: See notes from UBERONREF:0000002 subset: uberon_slim subset: vertebrate_core synonym: "tailbud" EXACT [] synonym: "tail bud mesenchyme " RELATED [ZFA:0000077] synonym: "end bud" RELATED [BTO:0001445] xref: EHDAA:1595 ! tail bud xref: VHOG:0000201 ! tail bud xref: MAT:0000070 ! tail bud xref: MIAA:0000070 ! tail bud xref: TAO:0000077 ! tail bud xref: XAO:0000107 ! tail bud xref: ZFA:0000077 ! tail bud xref: BTO:0001445 ! tail bud xref: EFO:0002748 ! tail bud xref: EHDAA2:0001976 ! tail bud xref: EMAPA:16580 ! tail bud is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo xref: AAO:0011104 ! tail bud property_value: external_definition "Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011104", date_retrieved="2012-06-20", source="ISBN:0815318960", source="OMD:tail+bud"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (5) a larva or embryo with a postanal tail.[well established][VHOG]" xsd:string {external_class="VHOG:0000201", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0010162 name: tail tip synonym: "end of tail" RELATED [MA:0002848] is_a: UBERON:0000479 {source="XAO"} ! tissue relationship: part_of UBERON:0007812 {source="MA"} ! post-anal tail xref: MA:0002848 ! tail tip xref: XAO:0004057 ! tail tip [Term] id: UBERON:0009741 name: tailbud stage def: "Any of the developmental stages from Nieuwkoop and Faber stage 20 to stage 44 (feeding), including the beginning of hatching (NF stage 35/36)." [ISBN:0815318960] is_a: UBERON:0000068 {source="XAO"} ! embryo stage xref: XAO:1000007 ! tailbud stage [Term] id: UBERON:0008897 ! fin name: fin def: "An external projection of an aquatic animal as a fish used in propelling or guiding the body[BTO]." [BTO:0004649, Wikipedia:Fin] comment: This class groups together various structures that may have arisen through convergent evolution, including, for example, the dorsal fin of a cetacean xref: EFO:0000875 ! fin xref: MAT:0000087 ! fin xref: MIAA:0000087 ! fin xref: OpenCyc:Mx4rvVjcBZwpEbGdrcN5Y29ycA xref: TAO:0000108 ! fin xref: XAO:0000002 ! fin xref: ZFA:0000108 ! fin xref: OpenCyc:Mx4rvVjcBZwpEbGdrcN5Y29ycA ! fin xref: BTO:0004649 ! fin xref: AAO:0010374 ! fin xref: MESH:A13.077 ! animal fins is_a: UBERON:0003102 ! surface structure is_a: UBERON:0000475 ! organism subdivision relationship: never_in_taxon NCBITaxon:8782 ! Aves relationship: confers_advantage_in ENVO:00000144 ! aquatic habitat xref: SCTID:73003005 ! Fin xref: AEO:0001004 ! fin xref: VSAO:0000099 ! fin property_value: external_definition "Surface structure involved in locomotion.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000108", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_definition "Surface structure involved in locomotion.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000099", date_retrieved="2012-08-14", source="TAO:curator"} [Term] id: UBERON:0002534 ! paired fin name: paired fin def: "Fin that is one of a pair located ventrally on the organism." [TAO:wd] subset: uberon_slim synonym: "pelvic/pectoral fin" EXACT [UBERON:cjm] is_a: UBERON:0004708 ! limb/fin is_a: UBERON:0008897 {source="ZFA"} ! fin relationship: develops_from UBERON:0002531 {source="ZFA"} ! fin bud relationship: never_in_taxon NCBITaxon:32523 ! Tetrapoda xref: ZFA:0005596 ! paired fin xref: TAO:0002278 ! paired fin xref: VSAO:0000111 ! paired fin synonym: "nageoire paire@fr" RELATED [VSAO:0000111] synonym: "artioptcérygie@fr" RELATED [VSAO:0000111] synonym: "nageoire paire@fr" RELATED [VSAO:0000111] [Term] id: UBERON:0002535 ! gill name: gill def: "Anatomical surface structure found in many aquatic organisms. It is a respiration organ whose function is the extraction of oxygen from water and the excretion of carbon dioxide. The microscopic structure of a gill is such that it presents a very large surface area to the external environment. Gills usually consist of thin filaments of tissue, branches, or slender tufted processes which have a highly folded surface to increase surface area. A high surface area is crucial to the gas exchange of aquatic organisms as water contains only 1/20 parts dissolved Oxygen compared to air. With the exception of some aquatic insects, the filaments and lamellae (folds) contain blood or coelomic fluid, from which gases are exchanged through the thin walls. Oxygen is carried by the blood to other parts of the body. Carbon dioxide passes from the blood through the thin gill tissue into the water. Gills or gill-like organs, located in different parts of the body, are found in various groups of aquatic animals, including mollusks, crustaceans, insects, fish, and amphibians." [Wikipedia:Gill] subset: functional_classification xref: MESH:A13.421 ! gill comment: this term potentially applicable across multiple metazoa - see also the subclass 'pharyngeal arch derived gill' is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0011150 ! pharyngeal arch derived gill name: pharyngeal arch derived gill subset: uberon_slim synonym: "branchia" RELATED [BTO:0000518] xref: BTO:0000518 xref: GAID:1218 ! gill xref: VHOG:0001214 ! gill xref: MAT:0000134 ! gill xref: MIAA:0000134 ! gill xref: OpenCyc:Mx4rvVi9dZwpEbGdrcN5Y29ycA xref: TAO:0000354 ! gill xref: XAO:0000120 ! external gill (also: UBERON:0008891 'external gill') xref: ZFA:0000354 ! gill xref: EFO:0000933 ! gill xref: OpenCyc:Mx4rvVi9dZwpEbGdrcN5Y29ycA ! gill xref: AAO:0010171 ! gill is_a: UBERON:0002535 ! gill relationship: site_of GO:0055074 ! calcium ion homeostasis relationship: develops_from UBERON:0008894 {source="XAO"} ! gill precursor xref: ncithesaurus:Gill ! gill property_value: external_definition "Anatomical structure consisting of a series of membranes which allow dissolved oxygen from the water to pass into the bloodstream and carbon dioxide to pass out of the bloodstream.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010171", date_retrieved="2012-06-20", source="AAO:BJB"} synonym: "gills" RELATED PLURAL [VHOG:0001214] property_value: external_definition "The respiratory organ of most aquatic animals that breathe water to obtain oxygen, consisting of a filamentous structure of vascular membranes across which dissolved gases are exchanged. [Free_Online_Dictionary]" xsd:string {ontology="VHOG", external_class="VHOG:0001214", date_retrieved="2012-09-17", source="http://www.thefreedictionary.com/gill", source="http://bgee.unil.ch/"} property_value: homology_notes "Gill slits in the pharyngeal region of the intestine, which are also present in (at least) tunicates and acranians, are taken over to the craniote ancestor.[well established][VHOG]" xsd:string {external_class="VHOG:0001214", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.209", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0017558 [Term] id: UBERON:0000205 name: papula def: "A thin protuberance on the surface of the body of an echinoderm containing diverticula of the water vascular system lined by ciliated peritoneum. Along with tube feet, provide the principle gas exchange surfaces.." [ISBN:0030229073] synonym: "papulli" EXACT PLURAL [] synonym: "papulae" EXACT PLURAL [ISBN:0030229073] is_a: UBERON:0002535 ! gill relationship: only_in_taxon NCBITaxon:7586 ! Echinodermata created_by: cjm creation_date: 2009-04-18T01:13:57Z [Term] id: UBERON:0008891 name: external gill def: "External gills are the gills of an animal, most typically an amphibian, that are exposed to the environment, rather than set inside the pharynx and covered by gill slits, as they are in most fishes[BTO]." [BTO:0004689, Wikipedia:External_gills] xref: XAO:0000120 ! gill (also: UBERON:0011150 'pharyngeal arch derived gill') xref: BTO:0004689 ! external gill is_a: UBERON:0003102 {source="XAO"} ! surface structure is_a: UBERON:0002535 {source="BTO"} ! gill xref: AAO:0010174 ! external gill property_value: external_definition "External gills are the gills of an animal, most typically an amphibian, that are exposed to the environment, rather than set inside the pharynx and covered by gill slits, as they are in most fishes. Instead, the respiratory organs are set on a frill of stalks protruding from the sides of an animals head. This type of gill is most commonly observed on the aquatic larva of most species of salamanders, lungfish, and bichirs (which have only one large pair), and are retained by neotenic adult salamanders and some species of adult lungfish. They are present on non-transforming salamander species such as the mudpuppy, as well as most members of the Proteidae and Sirenidae families, which naturally never metamorphose into an air-breathing form. The embryos of frogs and caecilians also develop external gills at some point in their development, though these are either resorbed before or disappear shortly after hatching. Fossils of the distant relatives of modern amphibians, such as Branchiosaurus and Apateon, also show evidence of external gills. The external gills commonly consist of a single stalk (rami) protruding from a gill arch behind the head of the animal, above an associated gill slit. The stalk usually contains muscle tissue, and may be moved by the animal as a free appendage, in order to stir up stagnant water. The stalk is lined by many thinly walled filaments (fimbriae), containing the majority of blood vessels used in gas exchange. Animals usually have one external gill originating on each gill arch (except the hyoid), which leads to there being three pairs of external gills in salamanders, and four in the gilled larvae of lungfish[Wikipedia:External_gills]." xsd:string {source="Wikipedia:External_gills"} [Term] id: UBERON:0008892 name: internal gill is_a: UBERON:0002535 {source="AAO"} ! gill xref: AAO:0010176 ! internal gill [Term] id: UBERON:0008894 name: gill precursor def: "A primordium or bud that develops into a gill." [] is_a: UBERON:0001048 {source="XAO"} ! primordium relationship: develops_from UBERON:0003114 {source="XAO"} ! pharyngeal arch 3 relationship: develops_from UBERON:0003115 {source="XAO"} ! pharyngeal arch 4 relationship: develops_from UBERON:0004117 {source="ZFA"} ! pharyngeal pouch synonym: "internal gill bud" EXACT [ZFA:0001107] synonym: "gill primordium" EXACT [XAO:0000448] xref: XAO:0000448 ! gill primordium xref: ZFA:0001107 ! internal gill bud xref: TAO:0001107 ! internal gill bud [Term] id: UBERON:0002536 name: arthropod sensillum def: "Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]" [FBbt:00007152, Wikipedia:Sensillum] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology subset: uberon_slim synonym: "sensillum" EXACT [FBbt:00007152, HAO:0000933] xref: BTO:0001237 xref: FBbt:00007152 ! sensillum xref: HAO:0000933 ! sensillum xref: MAT:0000163 ! sensillum xref: MIAA:0000163 ! sensillum xref: EFO:0000939 ! sensillum xref: TGMA:0000540 ! sensillum is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0001016 ! nervous system relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0007197 ! hermaphroditic organism name: hermaphroditic organism def: "Multi-cellular organism that can produce both male and female gametes." [CARO:MAH] synonym: "dioecious organism" RELATED [BILA:0000029] synonym: "hermaphrodite" RELATED [WBbt:0007849] xref: CARO:0000029 xref: BILA:0000029 ! hermaphroditic organism xref: HAO:0000029 ! hermaphroditic organism xref: TADS:0000601 ! hermaphroditic organism xref: WBbt:0007849 ! hermaphrodite is_a: UBERON:0000468 ! multi-cellular organism xref: AAO:0010035 ! hermaphroditic organism [Term] id: UBERON:0010895 name: sequential hermaphroditic organism def: "Hermaphroditic organism that produces gametes first of one sex, and then later of the other sex." [CARO:0000045] synonym: "consecutive hermaphroditic organism" RELATED [CARO:0000045] is_a: UBERON:0007197 {source="CARO"} ! hermaphroditic organism xref: CARO:0000045 ! sequential hermaphroditic organism xref: AAO:0010037 ! sequential hermaphroditic organism xref: BILA:0000045 ! sequential hermaphroditic organism xref: HAO:0000045 ! sequential hermaphroditic organism xref: TADS:0000608 ! sequential hermaphroditic organism [Term] id: UBERON:0010899 name: synchronous hermaphroditic organism def: "Hermaphroditic organism that produces both male and female gametes at the same time." [CARO:0000046] synonym: "serially hermaphroditic organism" RELATED [CARO:0000046] synonym: "simultaneous hermaphroditic organism" RELATED [UBERON:cjm] is_a: UBERON:0007197 {source="CARO"} ! hermaphroditic organism intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: has_part UBERON:0000473 ! testis intersection_of: has_part UBERON:0000992 ! female gonad xref: CARO:0000046 ! synchronous hermaphroditic organism xref: AAO:0010046 ! synchronous hermaphroditic organism xref: BILA:0000046 ! synchronous hermaphroditic organism xref: HAO:0000046 ! synchronous hermaphroditic organism xref: TADS:0000609 ! synchronous hermaphroditic organism [Term] id: UBERON:0007198 name: hermaphrodite anatomical structure alt_id: AEO:0000177 def: "An anatomical structure present only in hermaphrodites." [JB:DEF] synonym: "hermaphrodite-specific" RELATED [WBbt:0005758] xref: EHDAA2:0003177 ! hermaphrodite anatomical structure xref: WBbt:0005758 ! hermaphrodite-specific xref: AEO:0000177 ! hermaphrodite anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: part_of UBERON:0007197 ! hermaphroditic organism [Term] id: UBERON:0002537 name: hermaphrodite gonad def: "a gonad with both testicular and ovarian aspects[WP]." [Wikipedia:Ovotestis] synonym: "ovotestis" RELATED [BTO:0000981] synonym: "hermaphrodite genitalia" EXACT [GO:0040035] synonym: "hermaphrodite gland" NARROW SENSU [Wikipedia:Ovotestis#In_gastropods] synonym: "glandula hermaphroditica" NARROW SENSU [Wikipedia:Ovotestis#In_gastropods] xref: MAT:0000165 ! hermaphrodite gonad xref: MIAA:0000165 ! hermaphrodite gonad xref: WBbt:0005178 ! hermaphrodite gonad xref: EFO:0000971 ! hermaphrodite gonad xref: BTO:0000981 ! ovotestis intersection_of: UBERON:0000991 ! gonad intersection_of: capable_of GO:0007283 ! spermatogenesis intersection_of: capable_of GO:0048477 ! oogenesis relationship: part_of UBERON:0007197 ! hermaphroditic organism [Term] id: UBERON:0002538 name: hatching gland def: "The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process[GO]. A transversely oriented set of cells located deep to the EVL on the pericardial membrane, especially prominent during pharyngula period because of the brightly refractile cytoplasmic granules (containing hatching enzymes) of the principal cells of the gland. Kimmel et al, 1995." [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "frontal gland" RELATED [] synonym: "hgg" RELATED [] xref: BTO:0000558 xref: EFO:0000863 ! hatching gland xref: VHOG:0000078 ! hatching gland xref: MAT:0000180 ! hatching gland xref: MIAA:0000180 ! hatching gland xref: TAO:0000026 ! hatching gland xref: XAO:0000034 ! hatching gland xref: ZFA:0000026 ! hatching gland is_a: UBERON:0002530 {source="GO"} ! gland relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000924 ! ectoderm xref: AAO:0011050 ! hatching gland property_value: external_definition "A transversely oriented set of cells located deep to the EVL on the pericardial membrane, especially prominent during pharyngula period because of the brightly refractile cytoplasmic granules (containing hatching enzymes) of the principal cells of the gland. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000026", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0008906 name: lateral line nerve def: "Cranial nerves that carry afferent and efferent fibers for the lateral line system." [ZFIN:curator] synonym: "lateral line nerves" EXACT PLURAL [ZFA:0001479] xref: TAO:0001479 ! lateral line nerve is_a: UBERON:0001785 {source="AAO"} ! cranial nerve relationship: part_of UBERON:0002540 {source="ZFA"} ! lateral line system intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002540 ! lateral line system relationship: develops_from UBERON:0009128 {source="NBK53175"} ! lateral line placode xref: ZFA:0001479 ! lateral line nerve xref: AAO:0010077 ! lateral line nerve property_value: external_definition "Any of the sensory nerves that innervate mechano- and electroreceptors of the lateral line system. The lateral line nerves may be separated in two components, anterior and posterior, in relation to the position of its roots with respect to the otic capsule. These nerves develop from lateral line placodes.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010077", date_retrieved="2012-06-20", source="AAO:SIQ"} property_value: axiom_lost_from_external_ontology "relationship loss: innervates lateral line receptor organ (AAO:0001001)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010077", date_retrieved="2012-06-20"} property_value: axiom_lost_from_external_ontology "relationship type change: part_of_proxy lateral line system (AAO:0000975) CHANGED TO: part_of lateral line system (UBERON:0002540)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010077", date_retrieved="2012-06-20"} [Term] id: UBERON:0002540 name: lateral line system def: "a line of neuroblasts along the sides of fish and amphibia that detect vibrations and pressure changes." [ISBN:0471209627, ISBN:0815318960, Wikipedia:Lateral_line_system] subset: uberon_slim synonym: "lateral line stitches" RELATED [] synonym: "lateral-line organs" RELATED [] synonym: "ll" RELATED [] xref: AAO:0000269 ! lateral_line_system xref: VHOG:0001243 ! lateral line system xref: MAT:0000249 ! lateral line system xref: MIAA:0000249 ! lateral line system xref: TAO:0000034 ! lateral line system xref: XAO:0000095 ! lateral line system xref: ZFA:0000034 ! lateral line system xref: EFO:0000941 ! lateral line system is_a: UBERON:0001032 ! sense organ system relationship: part_of UBERON:0000010 ! peripheral nervous system relationship: never_in_taxon NCBITaxon:32524 {source="http://tolweb.org/Amniota"} ! Amniota relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: AAO:0000975 ! lateral line system property_value: external_definition "Sensory system which develops from a specialized series of dorsolateral ectodermal placodes named lateral line placodes.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000975", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship loss: is_formed_by lateral line receptor organ (AAO:0001001)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000975", date_retrieved="2012-06-20"} property_value: external_definition "A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000034", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "lateral line organs" RELATED [VHOG:0001243] property_value: homology_notes "The mechanosensory lateral line system is widely distributed in aquatic anamniotes. It was apparently present in the earliest vertebrates, as it has been identified in agnathans, cartilaginous fishes, bony fishes, lungfishes, the crossopterygian Latimeria, and aquatic amphibians.[well established][VHOG]" xsd:string {external_class="VHOG:0001243", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.195", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009128 ! lateral line placode name: lateral line placode synonym: "lateral line placodes" RELATED PLURAL [XAO:0000440] is_a: UBERON:0003067 {source="ISBN10:0471888893"} ! dorsolateral placode xref: XAO:0000440 ! lateral line placode xref: AAO:0010718 ! lateral line placodes property_value: external_definition "Specialized series of dorsolateral ectodermal placodes.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010718", date_retrieved="2012-06-20", source="AAO:SIQ"} relationship: never_in_taxon NCBITaxon:32524 {source="http://tolweb.org/Amniota"} ! Amniota relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: UBERON:0010202 ! lateral line name: lateral line def: "The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear." [ZFA:0001469, Wikipedia:Lateral_line] synonym: "lateral lines" EXACT PLURAL [ZFA:0001469] xref: TAO:0001469 ! lateral line xref: AAO:0011128 ! lateral line is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0002540 {source="ZFA"} ! lateral line system relationship: develops_from UBERON:0009128 ! lateral line placode xref: ZFA:0001469 ! lateral line xref: XAO:0004002 ! lateral line [Term] id: UBERON:0002543 name: obsolete median fin skeleton def: "Postcranial axial skeleton that is unpaired and located on the sagittal plane of the organism." [TAO:wd] comment: Mistakenly placed in uberon, should remain domain of TAO for now synonym: "unpaired fin skeleton" EXACT [ZFA:0001123] synonym: "axial fin skeleton" EXACT [TAO:0001123] consider: MAT:0000277 ! median fin skeleton consider: MIAA:0000277 ! median fin skeleton consider: ZFA:0001123 ! axial fin skeleton consider: EFO:0000950 ! median fin skeleton !consider: VSAO:0000170 ! median fin skeleton is_obsolete: true [Term] id: UBERON:0002545 name: obsolete body ganglion synonym: "trunk ganglion" RELATED [] xref: EFO:0000901 ! body ganglion (also: UBERON:0007134 'trunk ganglion') xref: MAT:0000344 ! body ganglion (also: UBERON:0007134 'trunk ganglion') xref: MIAA:0000344 ! body ganglion (also: UBERON:0007134 'trunk ganglion') consider: WBbt:0005332 ! body ganglion is_obsolete: true [Term] id: UBERON:0007134 name: trunk ganglion def: "Ganglion which is located in the trunk." [ZFIN:curator] synonym: "trunk ganglia" EXACT PLURAL [ZFA:0001573] synonym: "body ganglion" EXACT [MAT:0000344] xref: TAO:0001573 ! trunk ganglion xref: ZFA:0001573 ! trunk ganglion xref: EFO:0000901 ! body ganglion (also: UBERON:0002545 'obsolete body ganglion') xref: MAT:0000344 ! body ganglion (also: UBERON:0002545 'obsolete body ganglion') xref: MIAA:0000344 ! body ganglion (also: UBERON:0002545 'obsolete body ganglion') intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0002547 name: tadpole def: "An an organism at the larval stage" [UBERON:cjm] subset: uberon_slim synonym: "tadpole stage" RELATED [] xref: BTO:0001347 xref: MAT:0000370 ! tadpole xref: MIAA:0000370 ! tadpole is_a: UBERON:0002548 ! larva intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0009849 ! tadpole stage [Term] id: UBERON:0009849 ! tadpole stage name: tadpole stage def: "wholly aquatic larval stage in the life cycle of an amphibian, particularly of a frog or toad[WP]. XAO: The stages from feeding to the end of metamorphosis. Encompasses Weisz's first-form tadpole (equivalent to NF stages 45 to 49), second-form tadpole (NF 49 to 56) and third-form tadpole (NF 56 to 60-plus) stages." [ISBN:0471209627, ISSN:0003-276X, Wikipedia:Tadpole] xref: XAO:1000008 ! tadpole (also: UBERON:0004728 'amphibian larval stage') is_a: UBERON:0000069 ! larval stage [Term] id: UBERON:0002548 name: larva def: "a distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva] comment: This class was created automatically from a combination of ontologies. TODO: discriminate between stages and organisms subset: uberon_slim synonym: "planula" NARROW [Wikipedia:Larva] synonym: "naupilus" NARROW [Wikipedia:Larva] synonym: "zoea" NARROW [Wikipedia:Larva] synonym: "nymph" NARROW [Wikipedia:Larva] synonym: "naiad" NARROW [Wikipedia:Larva] synonym: "caterpillar" NARROW [Wikipedia:Larva] synonym: "grub" NARROW [Wikipedia:Larva] synonym: "maggot" NARROW [Wikipedia:Larva] synonym: "wriggler" NARROW [Wikipedia:Larva] synonym: "trochophore" NARROW [Wikipedia:Larva] synonym: "veliger" NARROW [Wikipedia:Larva] synonym: "glochidium" NARROW [Wikipedia:Larva] synonym: "ammocoete" NARROW [Wikipedia:Larva] synonym: "leptocephalus" NARROW [Wikipedia:Larva] synonym: "tadpole" NARROW [Wikipedia:Larva] synonym: "bipinnaria" NARROW [Wikipedia:Larva] xref: BTO:0000707 xref: FBbt:00001727 ! larva xref: HAO:0000459 ! larva xref: OpenCyc:Mx4rwQCBvZwpEbGdrcN5Y29ycA ! larva xref: AEO:0000126 ! larva intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0000069 ! larval stage xref: TAO:0002048 ! larva property_value: external_definition "Whole organism that is premetamorphic or a very immature individual.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002048", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "larval organism" EXACT [TAO:0002048] property_value: has_relational_adjective "larval" xsd:string [Term] id: UBERON:0008265 name: echinopluteus larva def: "A planktonic and feeding larval form that possesses limb-like outgrowths bearing ciliated bands." [http://www.encyclopedia.com/doc/1O8-echinopluteuslarva.html] synonym: "pluteus larva" EXACT [] intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0008264 ! echinopluteus larval stage [Term] id: UBERON:0002549 name: ventral trigeminal tract def: "The ventral trigeminothalamic tract serves as pain, temperature, and light touch pathway from the face, head and neck. It receives input from trigeminal nerve, facial nerve, glossopharyngeal nerve and vagus nerve. It receives discriminative tactile and pressure input from the contralateral principal sensory nucleus of CN V, which terminates in the ventral posteromedial nucleus of the thalamus. It then ascends to the contralateral sensory cortex via three neurons . [WP,unvetted]." [Wikipedia:Ventral_trigeminal_tract] subset: uberon_slim synonym: "anterior trigeminothalamic tract" EXACT [FMA:72506] synonym: "trigeminal lemniscus-2" EXACT [FMA:72506] synonym: "ventral crossed tract" EXACT [FMA:72506] synonym: "ventral secondary ascending tract of v" EXACT [] synonym: "ventral trigeminal pathway" EXACT [FMA:72506] synonym: "ventral trigeminothalamic tract" EXACT [FMA:72506] xref: FMA:72506 ! Ventral trigeminal tract xref: NIF_GrossAnatomy:birnlex_1001 ! Ventral trigeminal tract is_a: UBERON:0002316 ! white matter of neuraxis synonym: "tractus trigeminothalamicus anterior" EXACT LATIN [FMA:TA, FMA:72506] [Term] id: UBERON:0002550 name: anterior hypothalamic region synonym: "chiasmal zone" EXACT [FMA:62027] xref: FMA:62027 ! Anterior hypothalamic region xref: NIF_GrossAnatomy:birnlex_1005 ! Anterior hypothalamic region is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001898 ! hypothalamus [Term] id: UBERON:0002551 name: interstitial nucleus of cajal synonym: "interstitial nucleus" EXACT [FMA:72432] synonym: "interstitial nucleus of medial longitudinal fasciculus (crosby)" EXACT [] synonym: "interstitial nucleus of medial longitudinal fasciculus" EXACT [FMA:72432] xref: FMA:72432 ! Interstitial nucleus of medial longitudinal fasciculus xref: NIF_GrossAnatomy:birnlex_1008 ! Interstitial nucleus of Cajal xref: ABA:INC ! Interstitial nucleus of Cajal xref: BM:MB-ICA ! interstitial nucleus of Cajal is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002044 {source="ABA"} ! ventral nucleus of posterior commissure synonym: "nucleus interstitialis" EXACT LATIN [FMA:TA, FMA:72432] xref: SCTID:369251002 ! Entire interstitial nucleus of Cajal [Term] id: UBERON:0002552 name: vestibulocerebellar tract def: "The vestibulocerebellar tract is a tract in the pontine tegmentum which connects the vestibular nerve and the cerebellar cortex. [WP,unvetted]." [Wikipedia:Vestibulocerebellar_tract] subset: uberon_slim synonym: "vestibulocerebellar fibers" EXACT [FMA:72508] xref: FMA:72508 ! Vestibulocerebellar tract xref: NIF_GrossAnatomy:birnlex_1009 ! Vestibulocerebellar tract is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0003023 ! pontine tegmentum [Term] id: UBERON:0002553 name: anatomical cavity def: "Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina." [FMA:67552] synonym: "cavity" BROAD [] subset: upper_level xref: FMA:67552 ! Anatomical cavity xref: NIF_GrossAnatomy:birnlex_1011 ! Anatomical cavity xref: galen:Cavity ! cavity is_a: UBERON:0000464 ! anatomical space relationship: location_of UBERON:0000463 ! portion of organism substance [Term] id: UBERON:0012466 name: extraembryonic cavities is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0000478 {source="EHDAA2-modified"} ! extraembryonic structure xref: EHDAA2:0000472 ! extraembryonic cavities xref: EMAPA:16054 ! cavities xref: VHOG:0000767 ! extraembryonic cavities [Term] id: UBERON:0010064 name: open anatomical space def: "An anatomical space with at least one opening to another space or the exterior." [AEO:0000221] intersection_of: UBERON:0000464 ! anatomical space intersection_of: has_quality PATO:0000610 ! open relationship: connected_to UBERON:0000464 {source="cjm"} ! anatomical space xref: EHDAA2:0004616 ! open anatomical space xref: AEO:0000221 ! open anatomical space [Term] id: UBERON:0012467 name: enclosed anatomical space def: "An anatomical space with no opening to another space or to the exterior." [AEO:0000222] synonym: "closed anatomical space" EXACT [] intersection_of: UBERON:0000464 ! anatomical space intersection_of: has_quality PATO:0000608 ! closed xref: AEO:0000222 ! enclosed anatomical space [Term] id: UBERON:0002554 name: regional part of superior colliculus subset: non_informative subset: inherited_grouping_class xref: FMA:85592 ! Segment of superior colliculus xref: NIF_GrossAnatomy:birnlex_1014 ! Regional part of superior colliculus is_a: UBERON:0002966 ! regional part of midbrain tectum intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001945 ! superior colliculus synonym: "segment of superior colliculus" RELATED [FMA:85592] synonym: "superior colliculus segment" RELATED [FMA:85592] def: "A multi-tissue structure that is part of a superior colliculus." [OBOL:automatic] [Term] id: UBERON:0002556 name: corticotectal tract synonym: "corticotectal fibers" EXACT [FMA:72419] synonym: "corticotectal fibres" EXACT [FMA:72419] xref: FMA:72419 ! Corticotectal tract xref: NIF_GrossAnatomy:birnlex_1016 ! Corticotectal tract xref: BM:CTT ! cortico-tectal tract is_a: UBERON:0002316 ! white matter of neuraxis synonym: "fibrae corticotectales" EXACT LATIN [FMA:TA, FMA:72419] [Term] id: UBERON:0002557 name: linear nucleus xref: FMA:72436 ! Linear nucleus xref: NIF_GrossAnatomy:birnlex_1018 ! Linear nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0002558 name: organ cavity synonym: "cavity of organ" EXACT [FMA:12237] subset: upper_level xref: FMA:12237 ! Organ cavity xref: NIF_GrossAnatomy:birnlex_1019 ! Organ cavity is_a: UBERON:0002553 ! anatomical cavity xref: SCTID:362606005 ! Entire organ cavity [Term] id: UBERON:0010262 ! operculum of brain name: operculum of brain synonym: "operculum" BROAD [HP:0100954] def: "The most posterior portion of the inferior frontal gyrus of the frontal lobe in the brain. In an axial plane, the Sylvian fissure extends from the operculum posteriorly to divide the frontal from the temporal lobe. Broca's area is a notable part of the operculum, which plays a key role in conversation or speech production, reading and writing. Its vascular supply comes from the M3 branches of the middle cerebral artery[WP]." [Wikipedia:Operculum_%28brain%29] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001869 {source="HP"} ! cerebral hemisphere xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/Operculum.png xref: SCTID:362351003 ! Entire operculum [Term] id: UBERON:0002560 name: temporal operculum synonym: "facies supratemporalis" EXACT [FMA:74891] synonym: "operculum temporale" RELATED LATIN [Wikipedia:Operculum_%28brain%29] xref: FMA:74891 ! Temporal operculum xref: NIF_GrossAnatomy:birnlex_1025 ! Temporal operculum is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0010262 ! operculum of brain xref: SCTID:369222001 ! Entire temporal operculum [Term] id: UBERON:0002947 name: frontal operculum synonym: "operculum frontale" RELATED LATIN [Wikipedia:Operculum_%28brain%29] xref: FMA:74886 ! Frontal operculum xref: NIF_GrossAnatomy:birnlex_751 ! Frontal operculum is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0010262 ! operculum of brain xref: SCTID:362352005 ! Entire frontal operculum [Term] id: UBERON:0002911 name: parietal operculum def: "The parietal operculum, forming the superior bank of the sylvian fissure, as studied in the cat, contains the secondary somatosensory representation, 'S-II', and a second somatotopic representation (parietal ventral, or PV). Anatomically, primate S-II receives inputs from area 3 and area 1, and projects to PV and area 7. PV has projections to area 5 and premotor areas. [WP,unvetted]." [Wikipedia:Parietal_operculum] subset: uberon_slim synonym: "operculum parietale" EXACT LATIN [NIF_GrossAnatomy:birnlex_4029] xref: FMA:74889 ! Parietal operculum xref: NIF_GrossAnatomy:birnlex_4029 ! Parietal operculum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/Operculum.png/200px-Operculum.png is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0010262 ! operculum of brain xref: SCTID:362353000 ! Entire parietal operculum [Term] id: UBERON:0002562 name: superior frontal sulcus def: "The superior frontal sulcus is a sulcus between the superior frontal gyrus and the middle frontal gyrus. [WP,unvetted]." [Wikipedia:Superior_frontal_sulcus] subset: uberon_slim synonym: "sulcus f1" EXACT [FMA:83755] synonym: "superior frontal fissure" EXACT [FMA:83755] synonym: "sulcus frontalis primus" EXACT [NIF_GrossAnatomy:birnlex_1030] synonym: "sulcus frontalis superior" EXACT [NIF_GrossAnatomy:birnlex_1030] xref: FMA:83755 ! Superior frontal sulcus xref: NIF_GrossAnatomy:birnlex_1030 ! Superior frontal sulcus xref: ncithesaurus:Superior_Frontal_Sulcus ! Superior Frontal Sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Gray726_Superior_frontal_sulcus.svg/200px-Gray726_Superior_frontal_sulcus.svg.png is_a: UBERON:0000093 ! sulcus xref: SCTID:279342009 ! Entire superior frontal sulcus synonym: "sulcus frontalis superior" RELATED LATIN [Wikipedia:Superior_frontal_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray726_Superior_frontal_sulcus.svg xref: UMLS:C0228198 [Term] id: UBERON:0002563 name: central nucleus of inferior colliculus synonym: "chief nucleus of inferior colliculus" EXACT [FMA:72413] synonym: "inferior colliculus, central nucleus" EXACT [FMA:72413] synonym: "nucleus of inferior colliculus (crosby)" EXACT [] xref: FMA:72413 ! Central nucleus of inferior colliculus xref: NIF_GrossAnatomy:birnlex_1035 ! Central nucleus of inferior colliculus xref: ABA:ICc ! Inferior colliculus, central nucleus xref: BM:MB-Tec-ICC ! central nucleus of inferior colliculus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001946 ! inferior colliculus relationship: spatially_disjoint_from UBERON:0002571 {source="ABA"} ! external nucleus of inferior colliculus [Term] id: UBERON:0007193 ! orbital gyrus name: orbital gyrus def: "The inferior or orbital surface of the frontal lobe is concave, and rests on the orbital plate of the frontal bone. It is divided into four orbital gyri by a well-marked H-shaped orbital sulcus. These are named, from their position, the medial, anterior, lateral, and posterior orbital gyri. The medial orbital gyrus presents a well-marked antero-posterior sulcus, the olfactory sulcus, for the olfactory tract; the portion medial to this is named the straight gyrus, and is continuous with the superior frontal gyrus on the medial surface." [Wikipedia:Orbital_gyri] synonym: "orbital gyri" EXACT PLURAL [Wikipedia:Orbital_gyri] xref: FMA:256194 ! orbital gyrus is_a: UBERON:0000200 ! gyrus xref: SCTID:280372002 ! Entire orbital gyrus synonym: "gyrus orbitales" RELATED LATIN [Wikipedia:Orbital_gyri] xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Human_brainstem_anterior_view_2_description.JPG [Term] id: UBERON:0002564 name: lateral orbital gyrus xref: FMA:62418 ! Lateral orbital gyrus xref: NIF_GrossAnatomy:birnlex_1036 ! Lateral orbital gyrus is_a: UBERON:0007193 ! orbital gyrus xref: SCTID:279195001 ! Lateral orbital gyrus [Term] id: UBERON:0002565 name: olivary pretectal nucleus def: "The pretectum, also known as the pretectal area, is a region of neurons found between the thalamus and midbrain. It receives binocular sensory input from retinal ganglion cells of the eyes, and is the region responsible for maintaining the pupillary light reflex. [WP,unvetted]." [Wikipedia:Olivary_pretectal_nucleus] subset: uberon_slim synonym: "anterior pretectal nucleus" EXACT [FMA:72405] synonym: "olivary nucleus of superior colliculus" EXACT [FMA:72405] synonym: "pretectal olivary nucleus" EXACT [FMA:72405] xref: FMA:72405 ! Olivary pretectal nucleus xref: NIF_GrossAnatomy:birnlex_1037 ! Olivary pretectal nucleus xref: ABA:OP ! Olivary pretectal nucleus xref: BM:MB-Tec-OPT ! olivary pretectal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001944 ! pretectal region relationship: spatially_disjoint_from UBERON:0002996 {source="ABA"} ! nucleus of optic tract relationship: spatially_disjoint_from UBERON:0002711 {source="ABA"} ! nucleus of posterior commissure relationship: spatially_disjoint_from UBERON:0006848 {source="ABA"} ! posterior pretectal nucleus synonym: "nucleus pretectalis anterior" EXACT LATIN [FMA:TA, FMA:72405] [Term] id: UBERON:0002566 name: superior precentral sulcus synonym: "precentral dimple" EXACT [FMA:83763] synonym: "superior part of precentral fissure" EXACT [FMA:83763] synonym: "sulcus praecentralis superior" EXACT [NIF_GrossAnatomy:birnlex_1038] synonym: "sulcus precentralis superior" EXACT [NIF_GrossAnatomy:birnlex_1038] xref: FMA:83763 ! Superior precentral sulcus xref: NIF_GrossAnatomy:birnlex_1038 ! Superior precentral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002567 name: basal part of pons synonym: "basal portion of pons" EXACT [FMA:72244] synonym: "base of pons" EXACT [FMA:72244] synonym: "basilar part of pons" EXACT [FMA:72244] synonym: "pons proper" EXACT [FMA:72244] synonym: "ventral portion of pons" EXACT [FMA:72244] xref: FMA:72244 ! Basal part of pons xref: NIF_GrossAnatomy:birnlex_1043 ! Basal part of pons is_a: UBERON:0000477 ! anatomical cluster relationship: has_part UBERON:0002152 ! middle cerebellar peduncle relationship: part_of UBERON:0000988 ! pons synonym: "pars basilaris pontis" EXACT LATIN [FMA:TA, FMA:72244] [Term] id: UBERON:0002568 name: amiculum of dentate nucleus synonym: "dentate nuclear amiculum" EXACT [FMA:72546] xref: FMA:72546 ! Amiculum of dentate nucleus xref: NIF_GrossAnatomy:birnlex_1044 ! Amiculum of dentate nucleus is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0002132 ! dentate nucleus [Term] id: UBERON:0002569 name: transverse temporal sulcus xref: FMA:83782 ! Transverse temporal sulcus xref: NIF_GrossAnatomy:birnlex_1045 ! Transverse temporal sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002570 name: medial orbital gyrus xref: FMA:62419 ! Medial orbital gyrus xref: NIF_GrossAnatomy:birnlex_1046 ! Medial orbital gyrus is_a: UBERON:0007193 ! orbital gyrus xref: SCTID:279194002 ! Medial orbital gyrus [Term] id: UBERON:0002571 name: external nucleus of inferior colliculus xref: FMA:72412 ! External nucleus of inferior colliculus xref: NIF_GrossAnatomy:birnlex_1047 ! External nucleus of inferior colliculus xref: ABA:ICe ! Inferior colliculus, external nucleus xref: BM:MB-Tec-ICX ! external nucleus of inferior colliculus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001946 ! inferior colliculus relationship: spatially_disjoint_from UBERON:0002563 {source="ABA"} ! central nucleus of inferior colliculus [Term] id: UBERON:0002572 name: principal pretectal nucleus xref: FMA:72402 ! Principal pretectal nucleus xref: NIF_GrossAnatomy:birnlex_1048 ! Principal pretectal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001944 ! pretectal region [Term] id: UBERON:0002574 name: regional part of inferior olivary complex subset: non_informative def: "A regional part of brain that is part of a inferior olivary complex [Automatically generated definition]." [OBOL:automatic] synonym: "inferior olivary complex segment" EXACT [FMA:71259] synonym: "segment of inferior olivary complex" EXACT [NIF_GrossAnatomy:birnlex_1052] xref: FMA:71259 ! Segment of inferior olivary complex xref: NIF_GrossAnatomy:birnlex_1052 ! Regional part of inferior olivary complex is_a: UBERON:0002678 ! regional part of medulla oblongata intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002127 ! inferior olivary complex [Term] id: UBERON:0002575 name: posterior orbital gyrus xref: FMA:80184 ! Posterior orbital gyrus xref: NIF_GrossAnatomy:birnlex_1054 ! Posterior orbital gyrus is_a: UBERON:0007193 ! orbital gyrus xref: SCTID:279197009 ! Posterior orbital gyrus [Term] id: UBERON:0009899 ! pole of cerebral hemisphere name: pole of cerebral hemisphere def: "The anterior end of the hemisphere is named the frontal pole. The posterior end is named the occipital pole. The anterior end of the temporal lobe, the temporal pole." [Wikipedia:Poles_of_cerebral_hemispheres] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001869 ! cerebral hemisphere synonym: "polus frontalis, polus occipitalis, polus temporalis" RELATED LATIN [Wikipedia:Poles_of_cerebral_hemispheres] xref: http://upload.wikimedia.org/wikipedia/commons/e/e3/Human_brain_lateral_view_description.JPG [Term] id: UBERON:0002795 name: frontal pole def: "Component of the frontal lobe. The rostral and caudal boundaries of the frontal pole are the superior frontal gyrus and the rostral division of the middle frontal gyrus respectively (Christine Fennama-Notestine)." [NIF_GrossAnatomy:birnlex_1716] subset: uberon_slim synonym: "polus frontalis" EXACT [NeuroNames:57] xref: FMA:74885 ! Frontal pole xref: NIF_GrossAnatomy:birnlex_1716 ! Frontal pole xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Human_brain_lateral_view_description.JPG/200px-Human_brain_lateral_view_description.JPG intersection_of: UBERON:0009899 ! pole of cerebral hemisphere intersection_of: part_of UBERON:0001870 ! frontal cortex xref: SCTID:314144002 ! Entire frontal pole [Term] id: UBERON:0002902 name: occipital pole def: "The anterior end of the hemisphere is named the frontal pole. The posterior end is named the occipital pole. The anterior end of the temporal lobe, the temporal pole. [WP,unvetted]." [Wikipedia:Occipital_pole] subset: uberon_slim synonym: "polus occipitalis" EXACT [NIF_GrossAnatomy:birnlex_4016] synonym: "polus occipitalis cerebri" RELATED [BTO:0001868] xref: FMA:74892 ! Occipital pole xref: NIF_GrossAnatomy:birnlex_4016 ! Occipital pole xref: BTO:0001868 ! occipital pole xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Human_brain_lateral_view_description.JPG/200px-Human_brain_lateral_view_description.JPG intersection_of: UBERON:0009899 ! pole of cerebral hemisphere intersection_of: part_of UBERON:0002021 ! occipital lobe relationship: part_of UBERON:0002021 {source="BTO"} ! occipital lobe xref: SCTID:314160003 ! Entire occipital pole [Term] id: UBERON:0002576 name: temporal pole def: "The anterior end of the hemisphere is named the frontal pole. The posterior end is named the occipital pole. The anterior end of the temporal lobe, the temporal pole. [WP,unvetted]." [Wikipedia:Temporal_pole] subset: uberon_slim synonym: "polus temporalis" EXACT [NeuroNames:126] xref: FMA:74890 ! Temporal pole xref: NIF_GrossAnatomy:birnlex_1055 ! Temporal pole xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e3/Human_brain_lateral_view_description.JPG/200px-Human_brain_lateral_view_description.JPG intersection_of: UBERON:0009899 ! pole of cerebral hemisphere intersection_of: part_of UBERON:0001871 ! temporal lobe xref: SCTID:314155002 ! Entire temporal pole [Term] id: UBERON:0002577 name: pericentral nucleus of inferior colliculus synonym: "cortex of inferior colliculus" EXACT [FMA:72411] xref: FMA:72411 ! Pericentral nucleus of inferior colliculus xref: NIF_GrossAnatomy:birnlex_1056 ! Pericentral nucleus of inferior colliculus xref: BM:MB-Tec-ICP ! pericentral nucleus of inferior colliculus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001946 ! inferior colliculus [Term] id: UBERON:0002578 name: sublentiform nucleus xref: FMA:72404 ! Sublentiform nucleus xref: NIF_GrossAnatomy:birnlex_1057 is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001944 ! pretectal region [Term] id: UBERON:0002579 name: regional part of medullary reticular formation subset: non_informative def: "A regional part of brain that is part of a medullary reticular formation [Automatically generated definition]." [OBOL:automatic] synonym: "medullary reticular formation segment" EXACT [FMA:73730] synonym: "segment of medullary reticular formation" EXACT [NIF_GrossAnatomy:birnlex_1060] xref: FMA:73730 ! Segment of medullary reticular formation xref: NIF_GrossAnatomy:birnlex_1060 ! Regional part of medullary reticular formation is_a: UBERON:0002678 ! regional part of medulla oblongata intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002559 ! medullary reticular formation [Term] id: UBERON:0002581 name: postcentral gyrus def: "The lateral postcentral gyrus is a prominent structure in the parietal lobe of the human brain and an important landmark. It was initially defined from surface stimulation studies of Penfield, and parallel surface potential studies of Bard, Woolsey, and Marshall. Although initially defined to be roughly the same as Brodmann areas 3, 1 and 2, more recent work by Kaas has suggested that for homogeny with other sensory fields only area 3 should be referred to as 'primary somatosensory cortex', as it received the bulk of the thalamocortical projection from the sensory input fields. [WP,unvetted]." [Wikipedia:Postcentral_gyrus] subset: uberon_slim synonym: "postcentral convolution" EXACT [FMA:61896] synonym: "posterior central gyrus" EXACT [FMA:61896] synonym: "postrolandic gyrus" EXACT [FMA:61896] xref: FMA:61896 ! Postcentral gyrus xref: NIF_GrossAnatomy:birnlex_1070 ! Postcentral gyrus xref: ncithesaurus:Postcentral_Gyrus ! Postcentral Gyrus xref: EFO:0001383 ! postcentral gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Postcentral_gyrus.png/200px-Postcentral_gyrus.png xref: BTO:0004354 ! postcentral gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001872 ! parietal lobe xref: SCTID:279167001 ! Entire postcentral gyrus xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Postcentral_gyrus.png xref: UMLS:C0152302 [Term] id: UBERON:0002582 name: anterior calcarine sulcus synonym: "anterior calcarine fissure" EXACT [FMA:83750] synonym: "sulcus calcarinus anterior" EXACT [NIF_GrossAnatomy:birnlex_1072] xref: FMA:83750 ! Anterior calcarine sulcus xref: NIF_GrossAnatomy:birnlex_1072 ! Anterior calcarine sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002584 name: regional part of vestibular nuclear complex subset: non_informative def: "A regional part of brain that is part of a vestibular nuclear complex [Automatically generated definition]." [OBOL:automatic] synonym: "segment of vestibular nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_1080] synonym: "vestibular nuclear complex segment" EXACT [FMA:71267] xref: FMA:71267 ! Segment of vestibular nuclear complex xref: NIF_GrossAnatomy:birnlex_1080 ! Regional part of vestibular nuclear complex is_a: UBERON:0002678 ! regional part of medulla oblongata intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002673 ! vestibular nuclear complex [Term] id: UBERON:0002585 name: central tegmental tract of midbrain xref: FMA:72456 ! Central tegmental tract of midbrain xref: NIF_GrossAnatomy:birnlex_1081 ! Central tegmental tract of midbrain is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001943 ! midbrain tegmentum xref: SCTID:369243000 ! Entire central tegmental tract of midbrain [Term] id: UBERON:0002586 name: calcarine sulcus def: "The calcarine fissure is an anatomical landmark located at the caudal end of the medial surface of the brain. [WP,unvetted]." [Wikipedia:Calcarine_sulcus] subset: uberon_slim synonym: "calcarine fissure" EXACT [FMA:83749] synonym: "sulcus calcarinus" EXACT [NIF_GrossAnatomy:birnlex_1086] xref: FMA:83749 ! Calcarine sulcus xref: NIF_GrossAnatomy:birnlex_1086 ! Calcarine sulcus xref: ncithesaurus:Calcarine_Sulcus ! Calcarine Sulcus xref: BM:Tel-Cx-CAS ! calcarine sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279355005 ! Calcarine sulcus xref: UMLS:C0228224 [Term] id: UBERON:0002587 name: nucleus subceruleus synonym: "nucleus subcaeruleus" EXACT LATIN [FMA:TA, FMA:72479] synonym: "subcaerulean nucleus" EXACT [FMA:72479] synonym: "subcoeruleus nucleus" EXACT [] synonym: "subceruleus nucleus" EXACT [] xref: FMA:72479 ! Nucleus subceruleus xref: NIF_GrossAnatomy:birnlex_1088 ! Nucleus subceruleus xref: ABA:SLC ! Subceruleus nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0003004 {source="ABA"} ! median raphe nucleus relationship: spatially_disjoint_from UBERON:0002148 {source="ABA"} ! locus ceruleus relationship: spatially_disjoint_from UBERON:0002267 {source="ABA"} ! laterodorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002047 {source="ABA"} ! pontine raphe nucleus [Term] id: UBERON:0002589 name: lateral corticospinal tract def: "The lateral corticospinal tract (also called the crossed pyramidal tract or lateral cerebrospinal fasciculus) is the largest part of the corticospinal tract. It extends throughout the entire length of the medulla spinalis, and on transverse section appears as an oval area in front of the posterior column and medial to the posterior spinocerebellar tract. Its fibres arise from cells in the motor area of the cerebral hemisphere of the opposite side. They pass downward in company with those of the anterior corticospinal tract through the same side of the brain as that from which they originate, but they cross to the opposite side in the medulla oblongata and descend in the lateral funiculus of the medulla spinalis. The lateral corticospinal tract controls movement of contralateral limbs. Control of more central axial and girdle muscles comes from the anterior corticospinal tract. [WP,unvetted]." [Wikipedia:Lateral_corticospinal_tract] subset: uberon_slim synonym: "lateral pyramidal tract" EXACT [FMA:72635] xref: FMA:72635 ! Lateral corticospinal tract xref: NIF_GrossAnatomy:birnlex_1095 ! Lateral corticospinal tract is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:369091005 ! Entire lateral corticospinal tract synonym: "tractus corticospinalis lateralis, fasciculus cerebrospinalis lateralis" RELATED LATIN [Wikipedia:Lateral_corticospinal_tract] xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg [Term] id: UBERON:0002591 name: oral part of spinal trigeminal nucleus xref: FMA:235322 ! Oral part of spinal trigeminal nucleus xref: NIF_GrossAnatomy:birnlex_1100 ! Oral part of spinal trigeminal nucleus xref: ABA:SPVO ! Spinal nucleus of the trigeminal, oral part is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001717 ! spinal nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002162 {source="ABA"} ! area postrema relationship: spatially_disjoint_from UBERON:0002610 {source="ABA"} ! cochlear nuclear complex relationship: spatially_disjoint_from UBERON:0002864 {source="ABA"} ! accessory cuneate nucleus relationship: spatially_disjoint_from UBERON:0007633 {source="ABA"} ! nucleus of trapezoid body relationship: spatially_disjoint_from UBERON:0002126 {source="ABA"} ! solitary tract nuclear complex relationship: spatially_disjoint_from UBERON:0002866 {source="ABA"} ! caudal part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002873 {source="ABA"} ! interpolar part of spinal trigeminal nucleus [Term] id: UBERON:0002592 name: juxtarestiform body def: "The juxtarestiform body is a subdivision of the inferior cerebellar peduncle, which comprises both the juxtarestiform and restiform bodies. [WP,unvetted]." [Wikipedia:Juxtarestiform_body] subset: uberon_slim xref: FMA:72613 ! Juxtarestiform body xref: NIF_GrossAnatomy:birnlex_1101 ! Juxtarestiform body is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:110687007 ! Juxtarestiform body xref: http://upload.wikimedia.org/wikipedia/commons/f/fc/Gray677.png [Term] id: UBERON:0002593 name: orbital operculum xref: FMA:74887 ! Orbital operculum xref: NIF_GrossAnatomy:birnlex_1102 ! Orbital operculum is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0010262 ! operculum of brain [Term] id: UBERON:0002594 name: dentatothalamic tract def: "The dentatothalamic tract (or dentatorubrothalamic tract) is a tract which connects the dentate nucleus and the thalamus. [WP,unvetted]." [Wikipedia:Dentatothalamic_tract] subset: uberon_slim synonym: "dentatothalamic fibers" EXACT [FMA:72462] xref: FMA:72462 ! Dentatothalamic tract xref: NIF_GrossAnatomy:birnlex_1104 ! Dentatothalamic tract is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001943 ! midbrain tegmentum synonym: "tractus dentatothalamicus" RELATED LATIN [Wikipedia:Dentatothalamic_tract] [Term] id: UBERON:0002595 name: orbital sulcus def: "The inferior or orbital surface of the frontal lobe is concave, and rests on the orbital plate of the frontal bone. It is divided into four orbital gyri by a well-marked H-shaped orbital sulcus" [Wikipedia:Orbital_sulcus] synonym: "sulci orbitalis" EXACT LATIN [] synonym: "orbital sulci" EXACT PLURAL [FMA:83770] synonym: "cruciate sulcus of campbell" EXACT [NIF_GrossAnatomy:birnlex_1112] synonym: "sulcus orbitalis" EXACT [NIF_GrossAnatomy:birnlex_1112] xref: FMA:83770 ! Orbital sulcus xref: NIF_GrossAnatomy:birnlex_1112 ! Orbital sulcus xref: ncithesaurus:Orbital_Sulcus ! Orbital Sulcus xref: BM:Tel-Cx-ORS ! orbital sulcus is_a: UBERON:0008334 {source="FMA"} ! subarachnoid sulcus xref: SCTID:314143008 ! Entire orbital sulci xref: UMLS:C0228206 [Term] id: UBERON:0013590 name: cruciate sulcus def: "a deep groove which runs transversely across the rostro-dorsal surface of the cerebrum and which is one of the landmarks on the cerebral cortex." [http://medical-dictionary.thefreedictionary.com/cruciate+sulcus] synonym: "cruciate sulci" EXACT PLURAL [] is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002596 name: ventral posterior nucleus def: "The ventral posterior nucleus is the somato-sensory relay nucleus in thalamus of the brain. [WP,unvetted]." [Wikipedia:Ventral_posterior_nucleus] subset: uberon_slim synonym: "ventral posterior thalamic nucleus" EXACT [FMA:62187] synonym: "ventrobasal complex" EXACT [FMA:62187] synonym: "ventrobasal nucleus" EXACT [FMA:62187] synonym: "nucleus ventrales posteriores" EXACT [NIF_GrossAnatomy:birnlex_1116] synonym: "nucleus ventralis posterior" EXACT [NIF_GrossAnatomy:birnlex_1116] xref: FMA:62187 ! Ventral posterior nucleus xref: NIF_GrossAnatomy:birnlex_1116 ! Ventral posterior nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: BTO:0004373 ! ventral posterior nucleus (also: UBERON:0002939 'ventral posteroinferior nucleus') xref: BTO:0004374 ! ventral posterior inferior nucleus (also: UBERON:0002939 'ventral posteroinferior nucleus') xref: EV:0100209 ! ventral posterior thalamic nucleus (also: UBERON:0002939 'ventral posteroinferior nucleus') xref: BM:Die-Th-VPI ! ventral posterior inferior nucleus of thalamus (also: UBERON:0002939 'ventral posteroinferior nucleus') is_a: UBERON:0002308 {source="FMA"} ! nucleus of brain relationship: part_of UBERON:0002776 {source="FMA"} ! ventral nuclear group xref: SCTID:279147005 ! Entire ventral posterior nucleus of thalamus xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png [Term] id: UBERON:0002151 name: pontine nuclear group def: "The pontine nuclei are a part of the pons which store the memory of intention during motor activity. Corticopontine fibres carry information from the primary motor cortex to the ipsilateral pontine nucleus in the ventral pons, and the pontocerebellar projection then carries that information to the contralateral cerebellum via the middle cerebellar peduncle. They therefore allow modification of actions in the light of their outcome, or error correction, and are hence important in learning motor skills. [WP,unvetted]." [Wikipedia:Pontine_nuclei] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "pontine nuclei" EXACT [] synonym: "pontine nucleus" EXACT [] synonym: "pontine nuclear group" EXACT [FMA:72512] synonym: "pontine nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_1516] synonym: "pontine gray" EXACT [NIF_GrossAnatomy:birnlex_1516] synonym: "nuclei pontis" RELATED [BTO:0003396] synonym: "pontine gray matter" RELATED [BTO:0003396] xref: FMA:72512 ! Pontine nuclear group xref: MA:0001021 ! pontine nucleus xref: BTO:0003396 ! pontine nucleus xref: NIF_GrossAnatomy:birnlex_1516 ! Pontine nuclear complex xref: ABA:PG ! Pontine gray xref: BM:Pons-PGr ! pontine gray is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002567 ! basal part of pons relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus xref: SCTID:304942009 ! Entire pontine nucleus synonym: "nuclei pontis" RELATED LATIN [Wikipedia:Pontine_nuclei] xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Lower_pons_horizontal_KB.svg [Term] id: UBERON:0007641 ! trigeminal nuclear complex name: trigeminal nuclear complex def: "The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]." [Wikipedia:Trigeminal_nerve_nuclei] comment: In MA and FMA this is part of the pons / pontime tegmentum. We weaken this to overlaps to avoid inconsistency. In NIF this is a composite structure spanning multiple regions, which is more appropriate. synonym: "trigeminal nuclei" EXACT [FMA:71248] xref: FMA:71248 ! trigeminal nuclear complex xref: NIF_GrossAnatomy:birnlex_4096 ! Trigeminal nuclear complex xref: BM:V ! trigeminal nuclear complex (also: UBERON:0002925 'trigeminal nucleus') is_a: UBERON:0007245 {source="FMA"} ! nuclear complex of neuraxis relationship: overlaps UBERON:0003023 {source="FMA"} ! pontine tegmentum relationship: continuous_with UBERON:0001645 ! trigeminal nerve synonym: "nuclei trigemini" RELATED LATIN [Wikipedia:Trigeminal_nerve_nuclei] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png [Term] id: UBERON:0002925 ! trigeminal nucleus name: trigeminal nucleus comment: note massive inconsistencies between GO, MA, wikipedia. Part of pons in MA, but this leads to inconsistencies with ABA. See https://sourceforge.net/tracker/?func=detail&aid=3291162&group_id=76834&atid=1205376 subset: uberon_slim synonym: "trigeminal nucleus" EXACT [FMA:71248] synonym: "trigeminal V nucleus" EXACT [MA:0001028] synonym: "nucleus mesencephalicus nervi trigemini" RELATED [BTO:0001074] synonym: "nucleus mesencephalicus trigeminalis" RELATED [BTO:0001074] synonym: "nucleus tractus mesencephali nervi trigeminalis" RELATED [BTO:0001074] synonym: "trigeminal nuclear complex nucleus" EXACT [FMA:71247] xref: FMA:71247 ! nucleus of trigeminal nuclear complex xref: GAID:604 ! trigeminal nuclei xref: BTO:0001074 ! trigeminal nucleus xref: MA:0001028 ! trigeminal V nucleus xref: ncithesaurus:Trigeminal_Nucleus ! Trigeminal Nucleus xref: MESH:A08.186.211.132.931 ! trigeminal nuclei xref: VHOG:0001353 ! trigeminal V nucleus xref: EV:0100271 ! trigeminal nucleus xref: NIF_GrossAnatomy:nifext_11 ! Trigeminal nucleus xref: BM:V ! trigeminal nuclear complex (also: UBERON:0007641 'trigeminal nuclear complex') is_a: UBERON:0002308 {source="FMA"} ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0007641 ! trigeminal nuclear complex xref: SCTID:280164007 ! Trigeminal nucleus synonym: "nucleus of trigeminal nuclear complex" EXACT [FMA:71247] def: "A nucleus of brain that is part of a trigeminal nuclear complex." [OBOL:automatic] xref: UMLS:C0040999 [Term] id: UBERON:0004132 ! trigeminal sensory nucleus name: trigeminal sensory nucleus def: "The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. The nucleus is divided into three parts, from rostral to caudal (top to bottom in humans): * The mesencephalic nucleus * The chief sensory nucleus (or pontine nucleus or main sensory nucleus or primary nucleus) * The spinal trigeminal nucleus[WP]." [Wikipedia:Trigeminal_nuclei] comment: TODO: check ZFA link. note this is part of medulla in ZFA, but we do not include this link here as it leads to inconsistencies subset: vertebrate_core synonym: "trigeminal sensory nucleus" EXACT [GO:0021730] synonym: "trigeminal V sensory nucleus" EXACT [MA:0001030] synonym: "sensory trigeminal nucleus" EXACT [ZFA:0000433] synonym: "sensory trigeminal V nucleus" EXACT [] xref: ZFA:0000433 ! sensory trigeminal nucleus xref: MA:0001030 ! trigeminal V sensory nucleus xref: VHOG:0001356 ! trigeminal V sensory nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png is_a: UBERON:0000126 {source="FMA"} ! cranial nerve nucleus relationship: part_of UBERON:0002925 {source="MA"} ! trigeminal nuclear complex xref: SCTID:280170001 ! Sensory trigeminal nucleus xref: TAO:0000433 ! sensory trigeminal nuclei synonym: "sensory trigeminal nuclei" EXACT PLURAL [TAO:0000433] [Term] id: UBERON:0002597 name: principal sensory nucleus of trigeminal nerve def: "The principal sensory nucleus (or chief sensory nucleus of V) is a group of second order neurons which have cell bodies in the dorsal Pons. It receives information about discriminative sensation and light touch of the face as well as conscious proprioception of the jaw via first order neurons of CN V. Most of the sensory information crosses the midline and travels to the contralateral ventral posteriomedial (VPM) of the thalamus via the Ventral Trigeminothalamic Tract, but information of the oral cavity travels to the ipsilateral Ventral Posteriomedial (VPM) of the thalamus via the Dorsal Trigeminothalamic Tract. [WP,unvetted]." [Wikipedia:Chief_sensory_nucleus, GO:0021730] comment: GO has pontine nucleus as a child of trigeminal sensory nucleus, WP says this is a synonym, but we have a separate class for this - UBERON:0002151 subset: uberon_slim synonym: "trigeminal V principal sensory nucleus" EXACT [MA:0002740] synonym: "trigeminal V chief sensory nucleus" EXACT [MA:0002740] synonym: "principal sensory nucleus" EXACT [] synonym: "principal sensory nucleus of trigeminal nerve" EXACT [FMA:54533] synonym: "chief sensory nucleus" EXACT [FMA:54533] synonym: "main sensory nucleus" EXACT [FMA:54533] synonym: "main sensory nucleus of cranial nerve v" EXACT [] synonym: "principal sensory trigeminal nucleus" EXACT [FMA:54533] synonym: "principal trigeminal nucleus" EXACT [FMA:54533] synonym: "superior trigeminal nucleus" EXACT [FMA:54533] synonym: "superior trigeminal sensory nucleus" EXACT [FMA:54533] synonym: "trigeminal nerve superior sensory nucleus" EXACT [FMA:54533] synonym: "pontine nucleus" RELATED INCONSISTENT [Wikipedia:Trigeminal_nuclei, GO:0021740] xref: FMA:54533 ! Principal sensory nucleus of trigeminal nerve xref: NIF_GrossAnatomy:birnlex_1120 ! Principal sensory nucleus of trigeminal nerve xref: MA:0002740 ! trigeminal V principal sensory nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png xref: EV:0100274 ! principal sensory xref: ABA:PSV ! Principal sensory nucleus of the trigeminal xref: BM:VP ! principal trigeminal nucleus is_a: UBERON:0004132 {source="MA"} ! trigeminal sensory nucleus relationship: part_of UBERON:0003023 {source="NIF"} ! pontine tegmentum relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception relationship: spatially_disjoint_from UBERON:0006840 {source="ABA"} ! nucleus of lateral lemniscus relationship: spatially_disjoint_from UBERON:0007634 {source="ABA"} ! parabrachial nucleus relationship: spatially_disjoint_from UBERON:0002128 {source="ABA"} ! superior olivary complex xref: ncithesaurus:Principal_Sensory_Nucleus_of_the_Trigeminal_Nerve ! Principal Sensory Nucleus of the Trigeminal Nerve xref: SCTID:369031008 ! Entire trigeminal nerve superior sensory nucleus xref: EHDAA2:0004628 ! trigeminal pontine sensory nucleus xref: UMLS:C0228701 [Term] id: UBERON:0001717 name: spinal nucleus of trigeminal nerve def: "The spinal trigeminal nucleus is a nucleus in the medulla that receives information about deep/crude touch, pain, and temperature from the ipsilateral face. The facial, glossopharyngeal, and vagus nerves also convey pain information from their areas to the spinal trigeminal nucleus. [WP,unvetted]." [Wikipedia:Spinal_trigeminal_nucleus] subset: uberon_slim synonym: "spinal nucleus of cranial nerve v" EXACT [] synonym: "spinal trigeminal nucleus" EXACT [GO:0021741] synonym: "trigeminal nerve spinal tract nucleus" EXACT [] synonym: "trigeminal spinal nucleus" EXACT [] synonym: "trigeminal v spinal sensory nucleus" EXACT [] xref: FMA:54565 ! Spinal nucleus of trigeminal nerve xref: GAID:605 ! spinal trigeminal nucleu xref: MA:0001053 ! trigeminal V spinal sensory nucleus xref: VHOG:0001357 ! trigeminal V spinal sensory nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png xref: MESH:A08.186.211.132.931.920 ! spinal trigeminal nucleu xref: BM:VSp ! spinal trigeminal nucleus is_a: UBERON:0004132 {source="MA"} ! trigeminal sensory nucleus relationship: part_of UBERON:0001896 {source="MA"} ! medulla oblongata xref: ncithesaurus:Nucleus_of_the_Spinal_Tract_of_the_Trigeminal_Nerve ! Nucleus of the Spinal Tract of the Trigeminal Nerve xref: SCTID:369033006 ! Entire trigeminal nerve spinal tract nucleus synonym: "nucleus spinalis nervi trigemini" RELATED LATIN [Wikipedia:Spinal_trigeminal_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png xref: UMLS:C0041000 [Term] id: UBERON:0001718 name: mesencephalic nucleus of trigeminal nerve def: "The mesencephalic nucleus is involved with proprioception of the face, that is, the feeling of position of the muscles. Unlike many nuclei within the CNS, the mesencephalic nucleus contains no chemical synapses but are electrically coupled. Instead, neurons of this nucleus are pseudounipolar cells receiving proprioceptive information from the jaw, and sending projections to the motor trigeminal nucleus to mediate monosynaptic jaw reflexes. It is also the only structure in the CNS to contain the cell bodies of a primary afferent, which are usually contained within ganglia. [WP,unvetted]." [Wikipedia:Mesencephalic_nucleus_of_trigeminal_nerve] comment: Development notes: develops from NC in some species[UBERONREF:0000002] Not of NC origin[doi:10.1002/dvdy.1197]. AO notes: part of midbrain tegmentum in NIF and MA. the neurons of the mesencephalic trigeminal nucleus are the only centrally located primary sensory neurons in amniotes; all others are extramedullary[PMID:11747082] subset: uberon_slim subset: vertebrate_core synonym: "Me5" BROAD [NIF_GrossAnatomy:birnlex_1010] synonym: "mesencephalic nucleus" BROAD [Wikipedia:Mesencephalic_nucleus_of_trigeminal_nerve] synonym: "mesencephalic trigeminal V nucleus" EXACT [] synonym: "mesencephalic trigeminal nucleus" EXACT [GO:0021739] synonym: "nucleus of mesencephalic root of v" EXACT [] synonym: "trigeminal nerve mesencepahlic nucleus" EXACT [] synonym: "trigeminal V mesencephalic nucleus" EXACT [MA:0001057] synonym: "trigeminal mesencephalic nucleus" EXACT [] xref: FMA:54568 ! Mesencephalic nucleus of trigeminal nerve xref: NIF_GrossAnatomy:birnlex_1010 ! Mesencephalic nucleus of trigeminal nerve xref: TAO:0000312 ! mesencephalic nucleus of trigeminal nerve xref: ZFA:0000312 ! mesencephalic nucleus of trigeminal nerve xref: MA:0001057 ! trigeminal V mesencephalic nucleus xref: VHOG:0001354 ! trigeminal V mesencephalic nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png xref: EV:0100252 ! mesencephalic trigeminal nucleus xref: BM:Pons-5ME ! mesencephalic trigeminal nucleus is_a: UBERON:0004132 ! trigeminal sensory nucleus relationship: part_of UBERON:0001891 {source="MA"} ! midbrain relationship: part_of UBERON:0001943 {source="NIF"} ! midbrain tegmentum relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception relationship: only_in_taxon NCBITaxon:7776 {source="ISBN:978-0-387-09845-6"} ! Gnathostomata xref: SCTID:369032001 ! Entire trigeminal nerve mesencephalic nucleus synonym: "nucleus mesencephalicus nervi trigemini" RELATED LATIN [Wikipedia:Mesencephalic_nucleus_of_trigeminal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png [Term] id: UBERON:0002633 name: motor nucleus of trigeminal nerve def: "The trigeminal motor nucleus contains motor neurons that innervate muscles of the first branchial arch, namely the muscles of mastication, the tensor tympani, tensor veli palatini, mylohyoid, and anterior belly of the digastric." [Wikipedia:Trigeminal_motor_nucleus] comment: note this in ZFA this is part of the medulla; pons is a dubious structure for zebrafish subset: vertebrate_core synonym: "motor nucleus of cranial nerve v" EXACT [] synonym: "motor nucleus of trigeminal nerve" EXACT [FMA:54562] synonym: "trigeminal motor nucleus" EXACT [ZFA:0001365] synonym: "motor nucleus V" EXACT [ZFA:0001365] synonym: "trigeminal V motor nucleus" EXACT [MA:0001029] synonym: "nV" EXACT [ZFA:0001365] synonym: "motor trigeminal nucleus" EXACT [BTO:0001075] xref: FMA:54562 ! Trigeminal motor nucleus xref: NIF_GrossAnatomy:birnlex_1222 ! Motor nucleus of trigeminal nerve xref: ZFA:0001365 ! trigeminal motor nucleus xref: MA:0001029 ! trigeminal V motor nucleus xref: VHOG:0001355 ! trigeminal V motor nucleus xref: BTO:0001075 ! motor trigeminal nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png xref: EV:0100273 ! motor xref: ABA:V ! Motor nucleus of trigeminal xref: BM:Vm ! motor nucleus of trigeminal is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0000126 {source="FMA"} ! cranial nerve nucleus relationship: part_of UBERON:0000988 {source="ABA"} ! pons relationship: part_of UBERON:0003023 {source="NIF"} ! pontine tegmentum relationship: part_of UBERON:0002925 {source="MA"} ! trigeminal nuclear complex relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus synonym: "nucleus motorius nervi trigemini" EXACT LATIN [FMA:TA, FMA:54562] xref: ncithesaurus:Motor_Nucleus_of_the_Trigeminal_Nerve ! Motor Nucleus of the Trigeminal Nerve xref: SCTID:38390003 ! Trigeminal nerve motor nucleus xref: TAO:0001365 ! trigeminal motor nuclei synonym: "nucleus motorius nervi trigemini" RELATED LATIN [Wikipedia:Trigeminal_motor_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png synonym: "trigeminal motor nuclei" EXACT PLURAL [TAO:0001365] xref: UMLS:C0228700 [Term] id: UBERON:0002598 name: paracentral sulcus synonym: "sulcus subcentralis medialis" EXACT [NIF_GrossAnatomy:birnlex_1121] xref: FMA:83762 ! Paracentral sulcus xref: NIF_GrossAnatomy:birnlex_1121 ! Paracentral sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:369228002 ! Entire paracentral sulcus [Term] id: UBERON:0002599 name: medial olfactory gyrus xref: FMA:74509 ! Medial olfactory gyrus xref: NIF_GrossAnatomy:birnlex_1127 ! Medial olfactory gyrus is_a: UBERON:0000200 ! gyrus xref: SCTID:369103002 ! Entire medial olfactory gyrus [Term] id: UBERON:0002600 name: limbic lobe def: "The limbic lobe (also known as the Cingulate) is a portion of the brain associated with functions such as olfaction and emotion. It contains parts of other lobes, including the frontal, parietal, and temporal. Its main components are the fornicate gyrus, the hippocampus, and the amygdala It is related to the term limbic system, but unlike that term, 'limbic lobe' is a part of the Terminologia Anatomica, and there is less disagreement over what is included in the 'limbic lobe' than there is over what is included in the 'limbic system'. [WP,unvetted]." [Wikipedia:Limbic_lobe, Wikipedia:Limbic_lobe] subset: uberon_slim synonym: "fornicate gyrus" EXACT [FMA:72719] synonym: "grande lobe limbique of broca" EXACT [] synonym: "limbic lobe (carpenter)" EXACT [] xref: FMA:72719 ! Limbic lobe xref: NIF_GrossAnatomy:birnlex_1128 ! Limbic lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Human_brain_inferior-medial_view_description.JPG/200px-Human_brain_inferior-medial_view_description.JPG is_a: UBERON:0003022 ! lobe parts of cerebral cortex xref: SCTID:279215006 ! Limbic lobe synonym: "lobus limbicus" RELATED LATIN [Wikipedia:Limbic_lobe] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Human_brain_inferior-medial_view_description.JPG [Term] id: UBERON:0002601 name: fasciolar gyrus def: "a small paired band that passes around the splenium of the corpus callosum from the lateral longitudinal stria to the dentate gyrus[Biology-Online]. A posterior and upward extension of the dentate gyrus, forming a transitional area between the dentate gyrus and the indusium griseum[BTO]." [http://www.biology-online.org/dictionary/Fasciolar_gyrus, BTO:0002497] comment: TODO - existing definitions, synonyms and relationships in existing AOs seem contradictory; to be resolved. We take the dentate gyrus relationship from BTO, and it is also implied by the FMA synonym. However, FMA says archiortex (embryonic archicortex corresponds to the cortex of the dentate gyrus and hippocampus) and NIF says limbic lobe (which is more general than hippocampus). ABA xref made on basis of BTO related synonym synonym: "retrosplenial gyrus of hippocampus" EXACT [FMA:61921] synonym: "fasciola cinerea" RELATED [BTO:0002497] synonym: "gyrus fasciolaris" RELATED [BTO:0002497] xref: FMA:61921 ! Fasciolar gyrus xref: NIF_GrossAnatomy:birnlex_1129 ! Fasciolar gyrus xref: BTO:0002497 ! fasciolar gyrus xref: ABA:FC ! Fasciola cinerea is_a: UBERON:0000200 ! gyrus relationship: spatially_disjoint_from UBERON:0001954 {source="ABA"} ! Ammon's horn relationship: spatially_disjoint_from UBERON:0001885 {source="ABA"} ! dentate gyrus of hippocampal formation xref: SCTID:279210001 ! Entire fasciolar gyrus [Term] id: UBERON:0002602 name: emboliform nucleus def: "The emboliform nucleus lies immediately to the medial side of the nucleus dentatus, and partly covering its hilus. It is one among the four pairs of cerebellar nuclei, which are from lateral to medial: the dentate, interposed (emboliform and globose), and fastigial nuclei. These nuclei can be seen using the Weigert method staining. [WP,unvetted]." [Wikipedia:Emboliform_nucleus] subset: uberon_slim synonym: "anterior interposed nucleus" EXACT [FMA:72538] synonym: "anterior interpositus nucleus" EXACT [FMA:72538] xref: FMA:72538 ! Emboliform nucleus xref: NIF_GrossAnatomy:birnlex_1135 ! Emboliform nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002037 ! cerebellum relationship: part_of UBERON:0002130 ! cerebellar nuclear complex synonym: "nucleus interpositus anterior" EXACT LATIN [FMA:TA, FMA:72538] synonym: "nucleus emboliformis" RELATED LATIN [Wikipedia:Emboliform_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/2/23/Gray707.png [Term] id: UBERON:0002603 name: paraterminal gyrus def: "The paraterminal gyrus (subcallosal gyrus, peduncle of the corpus callosum) is a narrow lamina on the medial surface of the hemisphere in front of the lamina terminalis, behind the parolfactory area, and below the rostrum of the corpus callosum. It is continuous around the genu of the corpus callosum with the supracallosal gyrus. [WP,unvetted]." [Wikipedia:Paraterminal_gyrus] subset: uberon_slim synonym: "precommissural hippocampus" EXACT [FMA:61919] synonym: "subcallosal gyrus" EXACT [FMA:61919] xref: FMA:61919 ! Paraterminal gyrus xref: NIF_GrossAnatomy:birnlex_1138 ! Paraterminal gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray732.png/200px-Gray732.png is_a: UBERON:0002665 ! supracallosal gyrus synonym: "gyrus paraterminalis, gyrus subcallosus" RELATED LATIN [Wikipedia:Paraterminal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray732.png [Term] id: UBERON:0002605 name: precentral operculum xref: FMA:74888 ! Precentral operculum xref: NIF_GrossAnatomy:birnlex_1141 ! Precentral operculum is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0010262 ! operculum of brain [Term] id: UBERON:0002606 ! neuropil name: neuropil def: "A dense intricate feltwork of interwoven fine glial processes, fibrils, synaptic terminals, axons, and dendrites interspersed among the nerve cells of the central nervous system[MESH]" [Wikipedia:Neuropil, MESH:A08.637.500] subset: uberon_slim xref: FMA:261269 ! Neuropil xref: NIF_GrossAnatomy:birnlex_1142 xref: FBbt:00005139 ! neuropil xref: ncithesaurus:Neuropil ! Neuropil xref: GAID:740 ! neuropil xref: NIF_Subcellular:sao205380252 ! Neuropil xref: MESH:A08.637.500 ! neuropil xref: SCTID:67146008 ! Neuropil synonym: "neuropilus" RELATED LATIN [Wikipedia:Neuropil] is_a: UBERON:0005162 {source="FBbt"} ! multi cell component structure relationship: part_of UBERON:0001017 {source="FBbt"} ! central nervous system xref: UMLS:C0228081 [Term] id: UBERON:0001047 name: neural glomerulus alt_id: UBERON:FBbt_00005386 def: "Large synaptic bouton found in areas like olfactory bulb, cerebellar cortex and thalamus, that contacts many post-synaptic targets[NIF]." [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html, http://ccdb.ucsd.edu/SAO/images/glomerulus_sw_512x512.jpg] comment: isa or partof neuropil? TODO. Add to GO-CC? subset: uberon_slim synonym: "glomerulus" BROAD [FBbt:00005386, NIF_Subcellular:sao587858733] xref: FBbt:00005386 ! glomerulus xref: NIF_Subcellular:sao587858733 ! Glomerulus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray1130.svg/200px-Gray1130.svg.png is_a: UBERON:0002606 ! neuropil disjoint_from: UBERON:0000074 ! renal glomerulus [Term] id: UBERON:0011915 name: cerebellar glomerulus def: "An intertwined cluster of nerve fibers surrounded by glia where mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons" [MP:0004099, ISBN:0838580343] synonym: "cerebellar glomeruli" EXACT PLURAL [] intersection_of: UBERON:0001047 ! neural glomerulus intersection_of: part_of UBERON:0002037 ! cerebellum relationship: part_of UBERON:0002956 ! granular layer of cerebellar cortex xref: NIF_Subcellular:nlx_subcell_20090502 ! Cerebellar glomerulus [Term] id: UBERON:0011917 name: thalamic glomerulus def: "Synaptic structure found in thalamic relay nuclei consising of a complex of afferent terminals, relay cell dendrites, interneuron dendrites and other processes. These complexes are surrounded by astrocytic processes." [NIF_Subcellular:nlx_subcell_20090504] synonym: "thalamic glomeruli" EXACT PLURAL [] intersection_of: UBERON:0001047 ! neural glomerulus intersection_of: part_of UBERON:0001897 ! thalamus xref: NIF_Subcellular:nlx_subcell_20090504 ! Thalamic glomerulus [Term] id: UBERON:0002607 name: superior rostral sulcus synonym: "sulcus rostralis superior" EXACT [NIF_GrossAnatomy:birnlex_1143] xref: FMA:83766 ! Superior rostral sulcus xref: NIF_GrossAnatomy:birnlex_1143 ! Superior rostral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002608 name: caudal part of ventral lateral nucleus synonym: "dorsal part of ventral lateral posterior nucleus (jones)" EXACT [] synonym: "ventral lateral nucleus, caudal part" EXACT [FMA:62194] synonym: "ventral lateral thalamic nucleus, caudal part" EXACT [FMA:62194] synonym: "nucleus dorsooralis (van buren)" EXACT [NIF_GrossAnatomy:birnlex_1144] synonym: "nucleus lateralis intermedius mediodorsalis situs dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1144] synonym: "nucleus ventralis lateralis, pars caudalis" EXACT [NIF_GrossAnatomy:birnlex_1144] xref: FMA:62194 ! Caudal part of ventral lateral nucleus xref: NIF_GrossAnatomy:birnlex_1144 ! Caudal part of ventral lateral nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001925 ! ventral lateral nucleus [Term] id: UBERON:0002610 name: cochlear nuclear complex def: "The cochlear nuclei consist of: (a) the dorsal cochlear nucleus, corresponding to the tuberculum acusticum on the dorso-lateral surface of the inferior peduncle; and (b) the ventral or accessory cochlear nucleus, placed between the two divisions of the nerve, on the ventral aspect of the inferior peduncle. [WP,unvetted]." [Wikipedia:Cochlear_nuclei] subset: uberon_slim synonym: "cochlear nuclei" EXACT [FMA:72240] xref: FMA:72240 ! Cochlear nuclear complex xref: NIF_GrossAnatomy:birnlex_1151 ! Cochlear nuclear complex xref: ncithesaurus:Cochlear_Nuclei ! Cochlear Nuclei xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/52/Gray691.png/200px-Gray691.png xref: EV:0100260 ! cochlear nuclei xref: ABA:CN ! Cochlear nuclei xref: BM:Me-Co ! cochlear nuclei is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata relationship: spatially_disjoint_from UBERON:0002162 {source="ABA"} ! area postrema relationship: spatially_disjoint_from UBERON:0002864 {source="ABA"} ! accessory cuneate nucleus relationship: spatially_disjoint_from UBERON:0007633 {source="ABA"} ! nucleus of trapezoid body relationship: spatially_disjoint_from UBERON:0002126 {source="ABA"} ! solitary tract nuclear complex relationship: spatially_disjoint_from UBERON:0002866 {source="ABA"} ! caudal part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002873 {source="ABA"} ! interpolar part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002591 {source="ABA"} ! oral part of spinal trigeminal nucleus synonym: "nuclei cochleares" RELATED LATIN [Wikipedia:Cochlear_nuclei] xref: http://upload.wikimedia.org/wikipedia/commons/5/52/Gray691.png xref: UMLS:C0152411 [Term] id: UBERON:0002611 name: obsolete node of ranvier def: "." [Wikipedia:Node_of_ranvier] comment: in GO subset: uberon_slim synonym: "ranvier node" EXACT [FMA:67368] synonym: "ranvier's node" EXACT [FMA:67368] consider: FMA:67368 ! Node of Ranvier consider: NIF_GrossAnatomy:birnlex_1152 consider: ncithesaurus:Node_of_Ranvier ! Node of Ranvier consider: GO:0033268 ! node of Ranvier consider: GAID:748 ! ranvier's node is_obsolete: true [Term] id: UBERON:0002612 name: transverse orbital sulcus synonym: "sulcus orbitalis transversus" EXACT [NIF_GrossAnatomy:birnlex_1155] xref: FMA:83771 ! Transverse orbital sulcus xref: NIF_GrossAnatomy:birnlex_1155 ! Transverse orbital sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002613 name: globose nucleus def: "The globose nucleus is one of the deep cerebellar nuclei. It is located medial to the emboliform nucleus and lateral to the fastigial nucleus. This nucleus contains primarily large and small multipolar neurons. The globose nucleus and emboliform nucleus are occasionally referred to collectively as the interposed nucleus. [WP,unvetted]." [Wikipedia:Globose_nucleus] subset: uberon_slim synonym: "posterior interposed nucleus" EXACT [FMA:72536] synonym: "posterior interpositus nucleus" EXACT [FMA:72536] xref: FMA:72536 ! Globose nucleus xref: NIF_GrossAnatomy:birnlex_1158 ! Globose nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002130 ! cerebellar nuclear complex synonym: "nucleus interpositus posterior" EXACT LATIN [FMA:TA, FMA:72536] synonym: "nucleus globosus" RELATED LATIN [Wikipedia:Globose_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/2/23/Gray707.png [Term] id: UBERON:0002614 name: medial part of ventral lateral nucleus synonym: "ventral lateral nucleus, medial part" EXACT [FMA:62195] synonym: "ventral medial nucleus" EXACT [FMA:62195] synonym: "nucleus ventralis lateralis thalami, pars medialis" EXACT [NIF_GrossAnatomy:birnlex_1159] synonym: "nucleus ventrooralis medialis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1159] synonym: "ventral medial nucleus of thalamus" EXACT [NIF_GrossAnatomy:birnlex_1159] xref: FMA:62195 ! Medial part of ventral lateral nucleus xref: NIF_GrossAnatomy:birnlex_1159 ! Medial part of ventral lateral nucleus xref: ABA:VM ! Ventral medial nucleus of the thalamus xref: BM:Die-Th-VM ! ventral medial nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001925 ! ventral lateral nucleus [Term] id: UBERON:0002615 name: ventral tegmental decussation synonym: "anterior tegmental decussation" EXACT [FMA:72452] synonym: "decussation of forel" EXACT [] synonym: "ventral tegmental decussation of forel" EXACT [] xref: FMA:72452 ! Ventral tegmental decussation xref: NIF_GrossAnatomy:birnlex_1163 ! Ventral tegmental decussation is_a: UBERON:0007418 ! decussation of neuraxis relationship: part_of UBERON:0001943 ! midbrain tegmentum synonym: "decussatio tegmentalis anterior" EXACT LATIN [FMA:TA, FMA:72452] xref: SCTID:369249001 ! Entire ventral tegmental decussation [Term] id: UBERON:0002616 name: regional part of brain subset: non_informative def: "A multi-tissue structure that is part of a brain [Automatically generated definition]." [OBOL:automatic] synonym: "brain part" EXACT [] synonym: "neuraxis segment" EXACT [FMA:55676] synonym: "segment of brain" EXACT [NIF_GrossAnatomy:birnlex_1167] synonym: "anatomical structure of brain" EXACT [OBOL:automatic] synonym: "biological structure of brain" EXACT [OBOL:automatic] synonym: "brain anatomical structure" EXACT [OBOL:automatic] synonym: "brain biological structure" EXACT [OBOL:automatic] xref: FMA:55676 ! Segment of brain xref: NIF_GrossAnatomy:birnlex_1167 ! Regional part of brain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0000955 ! brain xref: SCTID:384763002 ! Brain region xref: ncithesaurus:Brain_Part ! Brain Part xref: UMLS:C0445620 [Term] id: UBERON:0002617 name: pars postrema of ventral lateral nucleus synonym: "posterodorsal part of ventral lateral posterior nucleus (jones)" EXACT [] synonym: "ventral lateral nucleus (pars postrema)" EXACT [FMA:62196] synonym: "nucleus dorsointermedius externus magnocellularis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1170] synonym: "nucleus lateralis intermedius mediodorsalis situs postremus" EXACT [NIF_GrossAnatomy:birnlex_1170] synonym: "nucleus ventralis lateralis thalami, pars postrema" EXACT [NIF_GrossAnatomy:birnlex_1170] xref: FMA:62196 ! Pars postrema of ventral lateral nucleus xref: NIF_GrossAnatomy:birnlex_1170 ! Pars postrema of ventral lateral nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001925 ! ventral lateral nucleus [Term] id: UBERON:0002618 name: trochlear nerve fibers alt_id: UBERON:0002674 synonym: "central part of trochlear nerve" EXACT [FMA:71116] synonym: "trochlear nerve fibers" EXACT [FMA:71116] synonym: "trochlear nerve root" EXACT [FMA:71116] synonym: "trochlear nerve tract" EXACT [FMA:71116] xref: FMA:71116 ! Trochlear nerve tract xref: NIF_GrossAnatomy:birnlex_1172 ! Trochlear nerve fibers is_a: UBERON:0006843 {source="FMA"} ! root of cranial nerve [Term] id: UBERON:0002619 name: regional part of cerebral cortex subset: non_informative alt_id: UBERON:0003208 def: "A regional part of brain that is part of a cerebral cortex [Automatically generated definition]." [OBOL:automatic] comment: todo - check MA term synonym: "cerebral cortex part" EXACT [] synonym: "segment of cerebral cortex" NARROW [NIF_GrossAnatomy:birnlex_1173] synonym: "region of cerebral cortex" EXACT [FMA:242193] xref: FMA:242193 ! Region of cerebral cortex xref: NIF_GrossAnatomy:birnlex_1173 ! Regional part of cerebral cortex xref: MA:0000187 ! neocortex region intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:119408004 ! Cerebral cortex part synonym: "neocortex region" EXACT [MA:0000187] synonym: "cerebral cortex region" RELATED [MA:0000187] [Term] id: UBERON:0002620 name: tuber cinereum def: "The tuber cinereum is a hollow eminence of gray matter situated between the mammilary bodies and the optic chiasm. The tuber cinereum is part of the hypothalamus. [WP,unvetted]." [Wikipedia:Tuber_cinereum] subset: uberon_slim xref: FMA:62327 ! Tuber cinereum xref: NIF_GrossAnatomy:birnlex_1189 ! Tuber cinereum xref: ncithesaurus:Tuber_Cinereum ! Tuber Cinereum xref: GAID:649 ! tuber cinereum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d7/Gray724.png/200px-Gray724.png xref: MESH:A08.186.211.730.385.357.352.870 ! tuber cinereum is_a: UBERON:0000477 ! anatomical cluster xref: SCTID:362381006 ! Entire tuber cinereum xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray724.png xref: UMLS:C0041283 [Term] id: UBERON:0002621 name: regional part of cochlear nuclear complex subset: non_informative def: "A regional part of brain that is part of a cochlear nuclear complex [Automatically generated definition]." [OBOL:automatic] synonym: "cochlear nuclear complex segment" EXACT [FMA:83952] synonym: "segment of cochlear nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_1195] xref: FMA:83952 ! Segment of cochlear nuclear complex xref: NIF_GrossAnatomy:birnlex_1195 ! Regional part of cochlear nuclear complex is_a: UBERON:0002678 ! regional part of medulla oblongata intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002610 ! cochlear nuclear complex [Term] id: UBERON:0002624 name: orbital part of inferior frontal gyrus synonym: "inferior frontal gyrus, orbital part" EXACT [FMA:61982] synonym: "pars orbitalis gyri frontalis inferioris" EXACT [NIF_GrossAnatomy:birnlex_1207] xref: FMA:61982 ! Orbital part of inferior frontal gyrus xref: NIF_GrossAnatomy:birnlex_1207 ! Orbital part of inferior frontal gyrus is_a: UBERON:0000064 ! organ part xref: ncithesaurus:Orbital_Part_of_the_Inferior_Frontal_Gyrus ! Orbital Part of the Inferior Frontal Gyrus xref: UMLS:C0262300 [Term] id: UBERON:0002626 name: head of caudate nucleus synonym: "caput (caudatus)" EXACT [FMA:61852] synonym: "caudate nuclear head" EXACT [FMA:61852] xref: FMA:61852 ! Head of caudate nucleus xref: NIF_GrossAnatomy:birnlex_1212 ! Head of caudate nucleus xref: EMAPA:18547 ! head of caudate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001873 ! caudate nucleus xref: SCTID:279298007 ! Entire head of caudate nucleus [Term] id: UBERON:0002627 name: capsule of medial geniculate body synonym: "medial geniculate body capsule" EXACT [FMA:62049] synonym: "capsula corporis geniculati medialis" EXACT [NIF_GrossAnatomy:birnlex_1214] xref: FMA:62049 ! Capsule of medial geniculate body xref: NIF_GrossAnatomy:birnlex_1214 ! Capsule of medial geniculate body is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001927 ! medial geniculate body [Term] id: UBERON:0002628 name: tail of caudate nucleus synonym: "caudate nuclear tail" EXACT [FMA:61854] xref: FMA:61854 ! Tail of caudate nucleus xref: NIF_GrossAnatomy:birnlex_1215 ! Tail of caudate nucleus xref: EMAPA:18548 ! tail of caudate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001873 ! caudate nucleus xref: SCTID:279299004 ! Entire tail of caudate nucleus [Term] id: UBERON:0002629 name: triangular part of inferior frontal gyrus synonym: "pars triangularis gyri frontalis inferioris" EXACT [NIF_GrossAnatomy:birnlex_1216] xref: FMA:61980 ! Triangular part of inferior frontal gyrus xref: NIF_GrossAnatomy:birnlex_1216 ! Triangular part of inferior frontal gyrus is_a: UBERON:0000064 ! organ part xref: ncithesaurus:Triangular_Part_of_the_Inferior_Frontal_Gyrus ! Triangular Part of the Inferior Frontal Gyrus xref: UMLS:C0262350 [Term] id: UBERON:0002630 name: body of caudate nucleus synonym: "caudate nuclear body" EXACT [FMA:61853] synonym: "corpus (caudatus)" EXACT [FMA:61853] xref: FMA:61853 ! Body of caudate nucleus xref: NIF_GrossAnatomy:birnlex_1217 ! Body of caudate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001873 ! caudate nucleus xref: SCTID:314175006 ! Entire body of caudate nucleus [Term] id: UBERON:0002631 name: cerebral crus def: "The cerebral crus is the anterior portion of the cerebral peduncle which contains the motor tracts, the plural of which is cerebral crura. In some older texts, it is used as a synonym for the entire cerebral peduncle, not just the anterior portion of it. [WP,unvetted]." [Wikipedia:Cerebral_crus] subset: uberon_slim synonym: "cerebral peduncle (clinical definition)" EXACT [FMA:72464] synonym: "crus cerebri" EXACT [EV:0100243] synonym: "base of cerebral peduncle" RELATED [BTO:0004677] synonym: "crus cerebri" RELATED [BTO:0004677] synonym: "crura cerebri" EXACT [MA:0001056] xref: MA:0001056 ! crura cerebri xref: BTO:0004677 ! basis pedunculi cerebri xref: FMA:72464 ! Cerebral crus xref: NIF_GrossAnatomy:birnlex_1218 ! Cerebral crus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Cn3nucleus.png/200px-Cn3nucleus.png xref: EV:0100243 ! crus cerebri is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0002623 {source="BTO"} ! cerebral peduncle xref: ncithesaurus:Crus_Cerebri ! Crus Cerebri synonym: "crus cerebri" RELATED LATIN [Wikipedia:Cerebral_crus] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Cn3nucleus.png relationship: in_lateral_side_of UBERON:0001891 {source="FMA-abduced-lr"} ! midbrain [Term] id: UBERON:0002632 name: medial part of medial mammillary nucleus synonym: "medial mammillary nucleus (carpenter)" EXACT [] synonym: "medial mammillary nucleus, medial part" EXACT [FMA:62345] synonym: "medial mammillary nucleus, median part" EXACT [FMA:62345] synonym: "medial subdivision of medial mammillary nucleus" EXACT [FMA:62345] xref: FMA:62345 ! Medial part of medial mammillary nucleus xref: NIF_GrossAnatomy:birnlex_1220 ! Medial part of medial mammillary nucleus xref: ABA:Mmme ! Medial mammillary nucleus, median part is_a: UBERON:0002020 ! gray matter of neuraxis [Term] id: UBERON:0002634 name: anterior nucleus of hypothalamus def: "The Anterior hypothalamic nucleus is a nucleus of the hypothalamus. Its function is thermoregulation (the maintenance of body temperature between certain parameters) of the body. [WP,unvetted]." [Wikipedia:Anterior_hypothalamic_nucleus] subset: uberon_slim synonym: "anterior hypothalamic area" EXACT [FMA:62319] synonym: "anterior hypothalamic nucleus" EXACT [FMA:62319] synonym: "fundamental gray substance" EXACT [FMA:62319] synonym: "parvocellular nucleus of hypothalamus" EXACT [FMA:62319] synonym: "nucleus anterior hypothalami" RELATED [BTO:0002450] xref: FMA:62319 ! Anterior nucleus of hypothalamus xref: NIF_GrossAnatomy:birnlex_1226 ! Anterior nucleus of hypothalamus xref: BTO:0002450 ! anterior hypothalamic nucleus xref: GAID:642 ! anterior hypothalamic nucleu xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8c/HypothalamicNuclei.PNG/200px-HypothalamicNuclei.PNG xref: MESH:A08.186.211.730.385.357.342.063 ! anterior hypothalamic nucleu xref: EV:0100231 ! anterior nucleus xref: ABA:AHN ! Anterior hypothalamic nucleus xref: BM:Die-Hy-HAA ! anterior hypothalamic area is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001928 ! preoptic area relationship: spatially_disjoint_from UBERON:0002206 {source="ABA"} ! mammillary body relationship: spatially_disjoint_from UBERON:0002035 {source="ABA"} ! medial preoptic nucleus relationship: spatially_disjoint_from UBERON:0002706 {source="ABA"} ! posterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0001935 {source="ABA"} ! ventromedial nucleus of hypothalamus synonym: "area hypothalamica rostralis" EXACT LATIN [FMA:TA, FMA:62319] xref: SCTID:369133009 ! Entire anterior hypothalamic nucleus synonym: "nucleus anterior hypothalami" RELATED LATIN [Wikipedia:Anterior_hypothalamic_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/HypothalamicNuclei.PNG [Term] id: UBERON:0002636 name: lateral pulvinar nucleus synonym: "lateral pulvinar nucleus of thalamus" EXACT [FMA:62181] synonym: "nucleus pulvinaris lateralis" EXACT [NIF_GrossAnatomy:birnlex_1228] synonym: "nucleus pulvinaris lateralis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1228] synonym: "nucleus pulvinaris lateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_1228] synonym: "nucleus pulvinaris thalami, pars lateralis" EXACT [NIF_GrossAnatomy:birnlex_1228] xref: FMA:62181 ! Lateral pulvinar nucleus xref: NIF_GrossAnatomy:birnlex_1228 ! Lateral pulvinar nucleus xref: BM:Die-Th-Pl-Pll ! lateral nucleus of pulvinar is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002637 name: ventral anterior nucleus def: "The ventral anterior nucleus is a nucleus of the thalamus. [WP,unvetted]." [Wikipedia:Ventral_anterior_nucleus] subset: uberon_slim synonym: "ventral anterior nucleus of thalamus" EXACT [FMA:62184] synonym: "ventral anterior thalamic nucleus" EXACT [FMA:62184] synonym: "nucleus lateropolaris" EXACT [NIF_GrossAnatomy:birnlex_1232] synonym: "nucleus ventralis anterior" EXACT [NIF_GrossAnatomy:birnlex_1232] synonym: "nucleus ventralis anterior thalami" EXACT [NIF_GrossAnatomy:birnlex_1232] synonym: "nucleus ventralis thalami anterior" EXACT [NIF_GrossAnatomy:birnlex_1232] synonym: "ventroanterior thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_1232] synonym: "ventroanterior nucleus of the thalamus" EXACT [] xref: FMA:62184 ! Ventral anterior nucleus xref: NIF_GrossAnatomy:birnlex_1232 ! Ventral anterior nucleus xref: BTO:0002468 ! ventral anterior nucleus of thalamus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: EV:0100199 ! anterior ventral thalamic nucleus (also: UBERON:0002685 'anteroventral nucleus') xref: BM:Die-Th-VA ! ventral anterior nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain xref: SCTID:279131008 ! Entire ventral anterior nucleus of thalamus xref: ncithesaurus:Ventroanterior_Nucleus_of_the_Thalamus ! Ventroanterior Nucleus of the Thalamus synonym: "nucleus ventralis anterior thalami" RELATED LATIN [Wikipedia:Ventral_anterior_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png xref: UMLS:C0175276 [Term] id: UBERON:0002638 name: medial pulvinar nucleus synonym: "nucleus pulvinaris medialis" EXACT [NIF_GrossAnatomy:birnlex_1233] synonym: "nucleus pulvinaris medialis thalami" EXACT [NIF_GrossAnatomy:birnlex_1233] synonym: "nucleus pulvinaris thalami, pars medialis" EXACT [NIF_GrossAnatomy:birnlex_1233] xref: FMA:62182 ! Medial pulvinar nucleus xref: NIF_GrossAnatomy:birnlex_1233 ! Medial pulvinar nucleus xref: BM:Die-Th-Pl-Plm ! medial nucleus of pulvinar is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002641 name: oral pulvinar nucleus synonym: "anterior pulvinar nucleus" EXACT [FMA:62180] synonym: "oral nuclear group of pulvinar" EXACT [FMA:62180] synonym: "oral part of pulvinar" EXACT [FMA:62180] synonym: "oral portion of pulvinar" EXACT [FMA:62180] synonym: "nucleus pulvinaris oralis" EXACT [NIF_GrossAnatomy:birnlex_1239] synonym: "nucleus pulvinaris oralis thalami" EXACT [NIF_GrossAnatomy:birnlex_1239] xref: FMA:62180 ! Oral pulvinar nucleus xref: NIF_GrossAnatomy:birnlex_1239 ! Oral pulvinar nucleus xref: BM:Die-Th-Pl-Pla ! anterior nucleus of pulvinar is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain synonym: "nucleus pulvinaris anterior" EXACT LATIN [FMA:TA, FMA:62180] [Term] id: UBERON:0007418 ! decussation of neuraxis name: decussation of neuraxis synonym: "neuraxis decussation" EXACT [FMA:83858] xref: FMA:83858 ! decussation of neuraxis is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002643 name: decussation of medial lemniscus def: "The sensory decussation or decussation of the lemniscus is a decussation or cross over of axons from the gracile nucleus and cuneate nucleus. The fibres of this decussation are called the internal arcuate fibres and are found at the superior aspect of the closed medulla superior to the motor decussation. It is part of the second neuron in the Posterior column-medial lemniscus pathway. [WP,unvetted]." [Wikipedia:Sensory_decussation] subset: uberon_slim synonym: "decussation of lemnisci" EXACT [FMA:72622] synonym: "decussation of lemniscus" EXACT [FMA:72622] synonym: "decussation of medial lemnisci" EXACT [FMA:72622] synonym: "medial lemniscus decussation" EXACT [FMA:72622] synonym: "medullary sensory decussation" EXACT [FMA:72622] synonym: "sensory decussation" EXACT [FMA:72622] xref: FMA:72622 ! Decussation of medial lemniscus xref: NIF_GrossAnatomy:birnlex_1245 ! Decussation of medial lemniscus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray759.png/200px-Gray759.png xref: BM:Me-LMX ! decussation of medial lemniscus is_a: UBERON:0007418 ! decussation of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata synonym: "decussatio lemnisci medialis" RELATED LATIN [Wikipedia:Sensory_decussation] xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Gray759.png [Term] id: UBERON:0002644 name: intermediate orbital gyrus xref: FMA:80183 ! Intermediate orbital gyrus xref: NIF_GrossAnatomy:birnlex_1247 ! Intermediate orbital gyrus is_a: UBERON:0007193 ! orbital gyrus [Term] id: UBERON:0002645 name: densocellular part of medial dorsal nucleus synonym: "nucleus medialis dorsalis paralamellaris (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1255] synonym: "nucleus medialis dorsalis, pars densocellularis" EXACT [NIF_GrossAnatomy:birnlex_1255] xref: FMA:62163 ! Densocellular part of medial dorsal nucleus xref: NIF_GrossAnatomy:birnlex_1255 ! Densocellular part of medial dorsal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis [Term] id: UBERON:0002646 name: dorsal longitudinal fasciculus of medulla def: "A dorsal longitudinal fasciculus that is part of a medulla [Automatically generated definition]." [OBOL:automatic] synonym: "bundle of Schutz of medulla" EXACT [OBOL:automatic] synonym: "fasciculus of Schutz of medulla" EXACT [OBOL:automatic] synonym: "medulla bundle of Schutz" EXACT [OBOL:automatic] synonym: "medulla dorsal longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "medulla fasciculus of Schutz" EXACT [OBOL:automatic] synonym: "medulla posterior longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "posterior longitudinal fasciculus of medulla" EXACT [OBOL:automatic] xref: FMA:72617 ! Dorsal longitudinal fasciculus of medulla xref: NIF_GrossAnatomy:birnlex_1257 ! Dorsal longitudinal fasciculus of medulla is_a: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: part_of UBERON:0000958 ! medulla relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0002649 name: dorsolateral fasciculus of medulla def: "." [Wikipedia:Lissauer's_tract] subset: uberon_slim synonym: "dorsolateral tract" EXACT [FMA:72616] synonym: "lissauer's tract" EXACT [FMA:72616] synonym: "posterolateral fasciculus" EXACT [FMA:72616] synonym: "posterolateral tract" EXACT [FMA:72616] synonym: "tract of lissauer" EXACT [] synonym: "zone of lissauer" EXACT [] xref: FMA:72616 ! Dorsolateral fasciculus of medulla xref: NIF_GrossAnatomy:birnlex_1267 ! Dorsolateral fasciculus of medulla xref: ncithesaurus:Tract_of_Lissauer ! Tract of Lissauer is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata synonym: "tractus posterolateralis" EXACT LATIN [FMA:TA, FMA:72616] xref: SCTID:369287009 ! Entire dorsolateral tract xref: UMLS:C0228587 [Term] id: UBERON:0002650 name: paralaminar part of medial dorsal nucleus synonym: "dorsomedial thalamic nucleus, paralaminar part" EXACT [FMA:62160] synonym: "paralaminar part of dorsomedial nucleus" EXACT [FMA:62160] synonym: "paralaminar part of medial dorsal nucleus of thalamus" EXACT [FMA:62160] synonym: "pars paralaminaris of medial dorsal nucleus of thalamus" EXACT [FMA:62160] synonym: "ventral mediodorsal nucleus" EXACT [FMA:62160] synonym: "mediodorsal thalamic nucleus, paralaminar part" EXACT [NIF_GrossAnatomy:birnlex_1276] synonym: "nucleus medialis dorsalis caudalis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1276] synonym: "nucleus medialis dorsalis thalami, pars multiformis" EXACT [NIF_GrossAnatomy:birnlex_1276] synonym: "nucleus medialis dorsalis, pars multiformis" EXACT [NIF_GrossAnatomy:birnlex_1276] synonym: "nucleus medialis dorsalis, pars paralaminaris" EXACT [NIF_GrossAnatomy:birnlex_1276] xref: FMA:62160 ! Paralaminar part of medial dorsal nucleus xref: NIF_GrossAnatomy:birnlex_1276 ! Paralaminar part of medial dorsal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis synonym: "pars paralaminaris nuclei mediodorsalis thalami" EXACT LATIN [FMA:TA, FMA:62160] [Term] id: UBERON:0002651 name: anterior horn of lateral ventricle def: "The anterior cornu (frontal horn, anterior horn; precornu) of the lateral ventricle passes forward and lateralward, with a slight inclination downward, from the interventricular foramen into the frontal lobe, curving around the anterior end of the caudate nucleus. Its floor is formed by the upper surface of the reflected portion of the corpus callosum, the rostrum. It is bounded medially by the anterior portion of the septum pellucidum, and laterally by the head of the caudate nucleus. Its apex reaches the posterior surface of the genu of the corpus callosum. [WP,unvetted]." [Wikipedia:Anterior_horn_of_lateral_ventricle] subset: uberon_slim synonym: "anterior horn of lateral ventricle" EXACT [FMA:74520] synonym: "frontal horn of lateral ventricle" EXACT [FMA:74520] xref: FMA:74520 ! Frontal horn of lateral ventricle xref: NIF_GrossAnatomy:birnlex_1279 ! Anterior horn of lateral ventricle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Gray735.png/200px-Gray735.png is_a: UBERON:0004086 ! brain ventricle relationship: part_of UBERON:0002285 ! telencephalic ventricle synonym: "cornu anterius ventriculi lateralis" EXACT LATIN [FMA:TA, FMA:74520] xref: ncithesaurus:Frontal_Horn_of_the_Lateral_Ventricle ! Frontal Horn of the Lateral Ventricle xref: SCTID:279247001 ! Entire anterior horn of lateral ventricle synonym: "cornu anterius" RELATED LATIN [Wikipedia:Anterior_horn_of_lateral_ventricle] xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray735.png xref: UMLS:C0152281 [Term] id: UBERON:0002654 name: parvicellular part of medial dorsal nucleus synonym: "dorsomedial thalamic nucleus, parvicellular part" EXACT [FMA:62162] synonym: "lateral mediodorsal nucleus" EXACT [FMA:62162] synonym: "lateral nucleus of medial dorsal nucleus of thalamus" EXACT [FMA:62162] synonym: "parvicellular part of dorsomedial nucleus" EXACT [FMA:62162] synonym: "parvocellular nucleus of medial dorsal nucleus of thalamus" EXACT [FMA:62162] synonym: "principal division of ventral anterior nucleus of thalamus" EXACT [FMA:62162] synonym: "mediodorsal thalamic nucleus, pars fasciculosa" EXACT [NIF_GrossAnatomy:birnlex_1283] synonym: "nucleus medialis dorsalis fasciculosis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1283] synonym: "nucleus medialis dorsalis nucleus fasciculosis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1283] synonym: "nucleus medialis dorsalis, pars parvicellularis" EXACT [NIF_GrossAnatomy:birnlex_1283] xref: FMA:62162 ! Parvicellular part of medial dorsal nucleus xref: NIF_GrossAnatomy:birnlex_1283 ! Parvicellular part of medial dorsal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis synonym: "pars parvocellularis lateralis nuclei mediodorsalis thalami" EXACT LATIN [FMA:TA, FMA:62162] synonym: "pars principalis nuclei ventralis anterior thalami" EXACT LATIN [FMA:TA, FMA:62162] [Term] id: UBERON:0002655 name: body of lateral ventricle def: "The body of lateral ventricle (cella) extends from the interventricular foramen to the splenium of the corpus callosum. It is an irregularly curved cavity, triangular on transverse section, with a roof, a floor, and a medial wall. The roof is formed by the under surface of the corpus callosum; the floor by the following parts, enumerated in their order of position, from before backward: the caudate nucleus of the corpus striatum, the stria terminalis and the terminal vein, the lateral portion of the upper surface of the thalamus, the choroid plexus, and the lateral part of the fornix; the medial wall is the posterior part of the septum pellucidum, which separates it from the opposite ventricle. [WP,unvetted]." [Wikipedia:Body_of_lateral_ventricle] subset: uberon_slim synonym: "central part of lateral ventricle" EXACT [FMA:83703] synonym: "lateral ventricular body" EXACT [FMA:83703] xref: FMA:83703 ! Body of lateral ventricle xref: NIF_GrossAnatomy:birnlex_1287 ! Body of lateral ventricle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Gray735.png/200px-Gray735.png is_a: UBERON:0004086 ! brain ventricle relationship: part_of UBERON:0002285 ! telencephalic ventricle synonym: "pars centralis ventriculi lateralis" EXACT LATIN [FMA:TA, FMA:83703] xref: ncithesaurus:Body_of_the_Lateral_Ventricle ! Body of the Lateral Ventricle xref: SCTID:279246005 ! Entire body of lateral ventricle synonym: "pars centralis ventriculi lateralis" RELATED LATIN [Wikipedia:Body_of_lateral_ventricle] xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray735.png xref: UMLS:C0152280 [Term] id: UBERON:0002656 name: periamygdaloid area synonym: "para-amygdaloid cortex" EXACT [FMA:62485] synonym: "periamygdaloid cortex" EXACT [FMA:62485] synonym: "periamygdaloid region" EXACT [FMA:62485] synonym: "semilunar gyrus" EXACT [FMA:62485] synonym: "ventral cortical nucleus of amygdala" EXACT [FMA:62485] xref: FMA:62485 ! Periamygdaloid area xref: NIF_GrossAnatomy:birnlex_1291 ! Periamygdaloid area xref: BM:Tel-Cx-PAM ! periamygdaloid area is_a: UBERON:0002020 ! gray matter of neuraxis [Term] id: UBERON:0002657 name: posterior parahippocampal gyrus synonym: "parahippocampal gyrus (amaral)" EXACT [] synonym: "parahippocampal gyrus (insausti)" EXACT [NIF_GrossAnatomy:birnlex_1295] xref: FMA:67966 ! Posterior parahippocampal gyrus xref: NIF_GrossAnatomy:birnlex_1295 ! Posterior parahippocampal gyrus is_a: UBERON:0000200 ! gyrus [Term] id: UBERON:0002658 name: medial lemniscus of midbrain def: "A medial lemniscus that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "midbrain medial lemniscus" EXACT [OBOL:automatic] xref: FMA:72461 ! Medial lemniscus of midbrain xref: NIF_GrossAnatomy:birnlex_1296 ! Medial lemniscus of midbrain is_a: UBERON:0003002 ! medial lemniscus intersection_of: UBERON:0003002 ! medial lemniscus intersection_of: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0002659 name: superior medullary velum def: "The superior medullary velum (anterior medullary velum, valve of Vieussens) is a thin, transparent of white substance, which stretches between the superior cerebellar peduncles; on the dorsal surface of its lower half the folia and lingula are prolonged. It forms, together with the superior cerebellar peduncle, the roof of the upper part of the fourth ventricle; it is narrow above, where it passes beneath the inferior colliculi, and broader below, where it is continuous with the white substance of the superior vermis. A slightly elevated ridge, the fraenulum veli, descends upon its upper part from between the inferior colliculi, and on either side of this the trochlear nerve emerges. Blood is supplied by branches from the superior cerebellar artery. [WP,unvetted]." [Wikipedia:Superior_medullary_velum] subset: uberon_slim synonym: "anterior medullary velum" EXACT [FMA:74508] xref: FMA:74508 ! Superior medullary velum xref: NIF_GrossAnatomy:birnlex_1300 ! Superior medullary velum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9b/Gray701.png/200px-Gray701.png is_a: UBERON:0003035 ! regional part of cerebellar white matter xref: SCTID:369269006 ! Entire superior medullary velum synonym: "velum medullare superius" RELATED LATIN [Wikipedia:Superior_medullary_velum] xref: http://upload.wikimedia.org/wikipedia/commons/9/9b/Gray701.png [Term] id: UBERON:0002660 name: medial longitudinal fasciculus of midbrain def: "A medial longitudinal fasciculus that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "midbrain medial longitudinal fasciculus" EXACT [OBOL:automatic] xref: FMA:72454 ! Medial longitudinal fasciculus of midbrain xref: NIF_GrossAnatomy:birnlex_1302 ! Medial longitudinal fasciculus of midbrain is_a: UBERON:0002309 ! medial longitudinal fasciculus intersection_of: UBERON:0002309 ! medial longitudinal fasciculus intersection_of: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0002661 name: superior frontal gyrus def: "The superior frontal gyrus makes up about one-third of the frontal lobe of the human brain. It is bounded laterally by the superior frontal sulcus. The superior frontal gyrus, like the inferior frontal gyrus and the middle frontal gyrus, is more of a region than a true gyrus. [WP,unvetted]." [Wikipedia:Superior_frontal_gyrus] subset: uberon_slim synonym: "marginal gyrus" EXACT [FMA:61857] synonym: "superior frontal convolution" EXACT [FMA:61857] xref: FMA:61857 ! Superior frontal gyrus xref: NIF_GrossAnatomy:birnlex_1303 ! Superior frontal gyrus xref: ncithesaurus:Superior_Frontal_Convolution ! Superior Frontal Convolution xref: EFO:0001991 ! superior frontal gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/50/Superior_frontal_gyrus.png/200px-Superior_frontal_gyrus.png xref: BTO:0004836 ! superior frontal gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001870 ! frontal lobe xref: SCTID:279166005 ! Entire superior frontal gyrus synonym: "gyrus frontalis superior" RELATED LATIN [Wikipedia:Superior_frontal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/5/50/Superior_frontal_gyrus.png xref: UMLS:C0152296 [Term] id: UBERON:0002662 name: medial pes lemniscus synonym: "superficial pes lemniscus" EXACT [FMA:72460] xref: FMA:72460 ! Medial pes lemniscus xref: NIF_GrossAnatomy:birnlex_1310 ! Medial pes lemniscus is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0002663 name: septal nuclear complex def: "The septal nuclei are structures in the middle anteroventral cerebrum that are composed of medium-size neurons grouped into medial, lateral, and posterior groups. The septal nuclei receive reciprocal connections from the olfactory bulb, hippocampus, amygdala, hypothalamus, midbrain, habenula, cingulate gyrus, and thalamus. The septal nuclei play a role in reward and reinforcement along with the nucleus accumbens. In the 1950s, Olds & Milner showed that rats with electrodes implanted in this area will self-stimulate repeatedly in order to experience a euphoric feeling (i.e. press a bar to receive electrical current that will stimulate the neurons). [WP,unvetted]." [Wikipedia:Septal_nuclei] comment: TODO - nucleus vs nuclear complex subset: uberon_slim synonym: "parolfactory nuclei" EXACT [FMA:61845] synonym: "septal nuclei" EXACT [FMA:61845] synonym: "septal nucleus" EXACT [MA:0002978] xref: FMA:61845 ! Septal nuclear complex xref: NIF_GrossAnatomy:birnlex_1313 ! Septal nuclear complex xref: GAID:637 ! septal nuclei xref: MA:0002978 ! septal nucleus xref: MESH:A08.186.211.577.750.800 ! septal nuclei xref: EHDAA2:0004709 ! septal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0000446 ! septum of telencephalon synonym: "nuclei septales" RELATED LATIN [Wikipedia:Septal_nuclei] [Term] id: UBERON:0002664 name: lateral part of medial mammillary nucleus synonym: "intercalated mammillary nucleus" EXACT [FMA:62346] synonym: "intermediate mammillary nucleus" EXACT [FMA:62346] synonym: "lateral mammillary nucleus (gagel)" EXACT [] synonym: "lateral subdivision of medial mammillary nucleus" EXACT [FMA:62346] synonym: "medial mammillary nucleus, lateral part" EXACT [FMA:62346] xref: FMA:62346 ! Lateral part of medial mammillary nucleus xref: NIF_GrossAnatomy:birnlex_1314 ! Lateral part of medial mammillary nucleus is_a: UBERON:0002020 ! gray matter of neuraxis [Term] id: UBERON:0002665 name: supracallosal gyrus def: "The supracallosal gyrus (indusium griseum; gyrus epicallosus) consists of a thin layer of grey matter in contact with the dorsal surface of the corpus callosum and continuous laterally with the grey matter of the cingulate gyrus. It contains two longitudinally directed strands of fibers termed respectively the medial and lateral longitudinal striae. The supracallosal gyrus is prolonged around the splenium of the corpus callosum as a delicate lamina, the fasciola cinerea, which is continuous below with the fascia dentata hippocampi. [WP,unvetted]." [Wikipedia:Supracallosal_gyrus] subset: uberon_slim synonym: "supracommissural hippocampal rudiment" EXACT [FMA:61920] synonym: "supracommissural hippocampus" EXACT [FMA:61920] xref: FMA:61920 ! Supracallosal gyrus xref: NIF_GrossAnatomy:birnlex_1316 ! Supracallosal gyrus xref: BTO:0003738 ! tenia tecta is_a: UBERON:0000200 ! gyrus xref: SCTID:369231001 ! Entire supracallosal gyrus [Term] id: UBERON:0002666 name: mesencephalic tract of trigeminal nerve synonym: "mesencephalic root of v" EXACT [] synonym: "mesencephalic trigeminal tract" EXACT [FMA:72489] xref: FMA:72489 ! Mesencephalic tract of trigeminal nerve xref: NIF_GrossAnatomy:birnlex_1318 ! Mesencephalic tract of trigeminal nerve is_a: UBERON:0002316 ! white matter of neuraxis xref: SCTID:369263007 ! Entire trigeminal nerve mesencephalic tract [Term] id: UBERON:0002667 name: lateral septal nucleus synonym: "lateral parolfactory nucleus" EXACT [FMA:61878] synonym: "lateral septum" EXACT [NIF_GrossAnatomy:birnlex_1321] synonym: "lateral septal nucleus (cajal)" EXACT [NIF_GrossAnatomy:birnlex_1321] synonym: "lateral septum nucleus" EXACT [NIF_GrossAnatomy:birnlex_1321] xref: FMA:61878 ! Lateral septal nucleus (also: UBERON:0007628 'lateral septal complex') xref: NIF_GrossAnatomy:birnlex_1321 ! Lateral septal nucleus xref: ABA:LS ! Lateral septal nucleus xref: BM:Tel-Spt-SLN ! lateral septal nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0001878 {source="ABA"} ! septofimbrial nucleus relationship: spatially_disjoint_from UBERON:0007630 {source="ABA"} ! septohippocampal nucleus [Term] id: UBERON:0002668 name: oculomotor nerve fibers comment: todo - make subclass of root of cranial nerve synonym: "oculomotor nerve fibers" EXACT [FMA:72457] synonym: "root of oculomotor nerve" EXACT [FMA:72457] synonym: "central part of oculomotor nerve" EXACT [FMA:72457] xref: FMA:72457 ! Central part of oculomotor nerve xref: NIF_GrossAnatomy:birnlex_1323 ! Oculomotor nerve fibers is_a: UBERON:0002211 ! nerve root relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0002669 name: anterior horizontal limb of lateral sulcus synonym: "anterior branch of lateral sulcus" EXACT [FMA:83760] synonym: "anterior horizontal limb of lateral fissure" EXACT [FMA:83760] synonym: "anterior horizontal ramus of lateral fissure" EXACT [FMA:83760] synonym: "anterior ramus of lateral cerebral sulcus" EXACT [FMA:83760] synonym: "horizontal limb of lateral fissure" EXACT [FMA:83760] synonym: "horizontal ramus of sylvian fissure" EXACT [] xref: FMA:83760 ! Anterior horizontal limb of lateral sulcus xref: NIF_GrossAnatomy:birnlex_1327 ! Anterior horizontal limb of lateral sulcus is_a: UBERON:0000464 ! anatomical space synonym: "ramus anterior sulci lateralis cerebri" EXACT LATIN [FMA:TA, FMA:83760] [Term] id: UBERON:0002670 name: anterior ascending limb of lateral sulcus synonym: "anterior ascending limb of lateral fissure" EXACT [FMA:83759] synonym: "anterior ascending ramus of lateral sulcus" EXACT [FMA:83759] synonym: "ascending branch of lateral sulcus" EXACT [FMA:83759] synonym: "ascending ramus of lateral cerebral sulcus" EXACT [FMA:83759] synonym: "ascending ramus of sylvian fissure" EXACT [] synonym: "middle ramus of lateral fissure" EXACT [FMA:83759] synonym: "superior branch of lateral fissure" EXACT [FMA:83759] xref: FMA:83759 ! Anterior ascending limb of lateral sulcus xref: NIF_GrossAnatomy:birnlex_1330 ! Anterior ascending limb of lateral sulcus is_a: UBERON:0000464 ! anatomical space synonym: "ramus ascendens sulci lateralis cerebri" EXACT LATIN [FMA:TA, FMA:83759] [Term] id: UBERON:0002671 name: pallidotegmental fasciculus synonym: "pallidotegmental tract" EXACT [FMA:72458] xref: FMA:72458 ! Pallidotegmental fasciculus xref: NIF_GrossAnatomy:birnlex_1331 ! Pallidotegmental fasciculus is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0002672 name: anterior subcentral sulcus xref: FMA:83765 ! Anterior subcentral sulcus xref: NIF_GrossAnatomy:birnlex_1332 ! Anterior subcentral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002675 name: diagonal sulcus xref: FMA:83758 ! Diagonal sulcus xref: NIF_GrossAnatomy:birnlex_1344 ! Diagonal sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002676 name: ventral supraoptic decussation def: "The ventral supraoptic decussation is the crossover point for signals from the left and right eye, en route respectively to the right and left sides of the visual cortex. Occupying the posterior part of the commissure of the optic chiasma is a strand of fibers, the Ventral supraoptic decussation (commissure of Gudden, Gudden's inferior commissure), which is not derived from the optic nerves; it forms a connecting link between the medial geniculate bodies. [WP,unvetted]." [Wikipedia:Ventral_supraoptic_decussation] subset: uberon_slim synonym: "Gudden commissure" EXACT [FMA:62052] synonym: "Gudden's commissure" EXACT [FMA:62052] synonym: "supraoptic commissures, ventral" EXACT [FMA:62052] synonym: "ventral supra-optic commissure" EXACT [FMA:62052] synonym: "commissure of Gudden" EXACT [NIF_GrossAnatomy:birnlex_1347] synonym: "ventral supraoptic commissure (of Meynert)" EXACT [NIF_GrossAnatomy:birnlex_1347] synonym: "ventral supraoptic decussation" EXACT [NIF_GrossAnatomy:birnlex_1347] synonym: "VSOX" EXACT [NIF_GrossAnatomy:birnlex_1347] synonym: "von Gudden's commissure" EXACT [FMA:62052] xref: FMA:62052 ! Ventral supraoptic decussation xref: NIF_GrossAnatomy:birnlex_1347 ! Ventral supraoptic decussation xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Gray722.png/200px-Gray722.png is_a: UBERON:0001020 {source="FMA"} ! commissure relationship: part_of UBERON:0002550 {source="FMA"} ! anterior hypothalamic region synonym: "commissura supraoptica ventralis" EXACT LATIN [FMA:TA, FMA:62052] synonym: "commissura supraoptica ventralis" RELATED LATIN [Wikipedia:Ventral_supraoptic_decussation] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png synonym: "ventral supraoptic decussation of gudden" RELATED [FMA:62052] [Term] id: UBERON:0002677 name: regional part of medullary raphe nuclear complex subset: non_informative def: "A regional part of brain that is part of a medullary raphe nuclear complex [Automatically generated definition]." [OBOL:automatic] synonym: "medullary raphe nuclear complex segment" EXACT [FMA:83951] synonym: "segment of medullary raphe nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_1349] xref: FMA:83951 ! Segment of medullary raphe nuclear complex xref: NIF_GrossAnatomy:birnlex_1349 ! Regional part of medullary raphe nuclear complex is_a: UBERON:0002678 ! regional part of medulla oblongata intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002692 ! medullary raphe nuclear complex [Term] id: UBERON:0002678 name: regional part of medulla oblongata subset: non_informative def: "A regional part of brain that is part of a medulla oblongata [Automatically generated definition]." [OBOL:automatic] synonym: "medullary oblongata segment" EXACT [FMA:71011] synonym: "segment of medulla oblongata" EXACT [NIF_GrossAnatomy:birnlex_1355] xref: FMA:71011 ! Segment of medulla oblongata xref: NIF_GrossAnatomy:birnlex_1355 ! Regional part of medulla oblongata intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:119241003 ! Medulla oblongata part [Term] id: UBERON:0002679 name: anterodorsal nucleus synonym: "anterodorsal nucleus of thalamus" EXACT [FMA:62141] synonym: "anterodorsal thalamic nucleus" EXACT [FMA:62141] synonym: "anterodorsal nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus anterior dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus anterior dorsalis thalami" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus anterior thalami dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus anterodorsalis" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus anterodorsalis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus anterodorsalis thalami" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus anterosuperior" EXACT [NIF_GrossAnatomy:birnlex_1358] synonym: "nucleus thalamicus anterodorsalis" EXACT [NIF_GrossAnatomy:birnlex_1358] xref: FMA:62141 ! Anterodorsal nucleus xref: NIF_GrossAnatomy:birnlex_1358 ! Anterodorsal nucleus xref: ABA:AD ! Anterodorsal nucleus xref: BM:Die-Th-AD ! anterodorsal nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002681 {source="ABA"} ! anteromedial nucleus relationship: spatially_disjoint_from UBERON:0002685 {source="ABA"} ! anteroventral nucleus relationship: spatially_disjoint_from UBERON:0002984 {source="ABA"} ! lateral dorsal nucleus xref: SCTID:279127002 ! Entire anterodorsal nucleus of thalamus [Term] id: UBERON:0002680 name: regional part of metencephalon subset: non_informative def: "A regional part of brain that is part of a metencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "metencephalon subdivision" EXACT [FMA:67942] synonym: "segment of metencephalon" EXACT [NIF_GrossAnatomy:birnlex_1361] xref: FMA:67942 ! Segment of metencephalon xref: NIF_GrossAnatomy:birnlex_1361 ! Regional part of metencephalon is_a: UBERON:0000477 ! anatomical cluster intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001895 ! metencephalon [Term] id: UBERON:0002681 name: anteromedial nucleus synonym: "anteromedial nucleus of thalamus" EXACT [FMA:62142] synonym: "anteromedial thalamic nucleus" EXACT [FMA:62142] synonym: "anteromedial nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_1365] synonym: "nucleus anterior medialis" EXACT [NIF_GrossAnatomy:birnlex_1365] synonym: "nucleus anterior medialis thalami" EXACT [NIF_GrossAnatomy:birnlex_1365] synonym: "nucleus anterior thalami medialis" EXACT [NIF_GrossAnatomy:birnlex_1365] synonym: "nucleus anteromedialis" EXACT [NIF_GrossAnatomy:birnlex_1365] synonym: "nucleus anteromedialis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1365] synonym: "nucleus anteromedialis thalami" EXACT [NIF_GrossAnatomy:birnlex_1365] synonym: "nucleus thalamicus anteromedialis" EXACT [NIF_GrossAnatomy:birnlex_1365] xref: FMA:62142 ! Anteromedial nucleus xref: NIF_GrossAnatomy:birnlex_1365 ! Anteromedial nucleus xref: ABA:AM ! Anteromedial nucleus xref: BM:Die-AM ! anteromedial nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002679 {source="ABA"} ! anterodorsal nucleus relationship: spatially_disjoint_from UBERON:0002685 {source="ABA"} ! anteroventral nucleus relationship: spatially_disjoint_from UBERON:0002984 {source="ABA"} ! lateral dorsal nucleus xref: SCTID:279128007 ! Entire anteromedial nucleus of thalamus [Term] id: UBERON:0002682 name: abducens nucleus def: "The abducens nucleus is the originating nucleus from which the abducens nerve emerges - a cranial nerve nucleus. This nucleus is located beneath the fourth ventricle in the caudal portion of the pons, medial to the sulcus limitans. The abducens nucleus along with the internal genu of the facial nerve make up the facial colliculus, a hump at the caudal end of the medial eminence on the dorsal aspect of the pons. [WP,unvetted]." [Wikipedia:Abducens_nucleus] comment: part of medulla oblongata in ABA and ZFA; part of pons in MA and pontine tegmentum in NIF; note that pons/medulla are spatially disjoint in ABA. subset: uberon_slim subset: vertebrate_core synonym: "abducens nerve nucleus" EXACT [FMA:54504] synonym: "abducent nucleus" EXACT [FMA:54504] synonym: "nucleus of abducens nerve" EXACT [FMA:54504] synonym: "nucleus of abducens nerve (VI)" EXACT [FMA:54504] synonym: "sixth cranial nerve nucleus" EXACT [FMA:54504] synonym: "abducens VI nucleus" EXACT [MA:0001010] synonym: "abducens motor nucleus" EXACT [ZFA:0000713] synonym: "motor nucleus VI" EXACT [ZFA:0000713] synonym: "nVI" EXACT [ZFA:0000713] xref: FMA:54504 ! Abducens nucleus xref: NIF_GrossAnatomy:birnlex_1366 ! Abducens nucleus xref: ZFA:0000713 ! abducens motor nucleus xref: MA:0001010 ! abducens VI nucleus xref: ncithesaurus:Abducens_Nucleus ! Abducens Nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray696.png/200px-Gray696.png xref: EV:0100266 ! abducent nucleus xref: ABA:VI ! Abducens nucleus xref: BM:Pons-VI ! abducens nucleus is_a: UBERON:0000126 {source="FMA"} ! cranial nerve nucleus relationship: part_of UBERON:0000988 {source="MA", source="NIF", source="GO", conflicts="ZFA", conflicts="ABA"} ! pons relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus synonym: "nucleus nervi abducentis" EXACT LATIN [FMA:TA, FMA:54504] xref: SCTID:280165008 ! Entire abducens nucleus xref: EHDAA2:0004310 ! abducens nucleus xref: TAO:0000713 ! abducens motor nuclei synonym: "nucleus nervi abducentis" RELATED LATIN [Wikipedia:Abducens_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png property_value: external_definition "Hindbrain motor nucleus which is the origin of motor axons of cranial nerve VI. From Neuroanatomy of the Zebrafish Brain.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000713", date_retrieved="2012-08-14", source="ISBN:3764351209"} synonym: "abducens motor nuclei" EXACT PLURAL [TAO:0000713] xref: UMLS:C0152407 [Term] id: UBERON:0002683 name: rhinal sulcus def: "In the human brain, the rhinencephalon appears as a longitudinal elevation, with a corresponding internal furrow, on the under surface of the hemisphere close to the lamina terminalis; it is separated from the lateral surface of the hemisphere by a furrow, the external rhinal fissure (or rhinal sulcus), and is continuous behind with that part of the hemisphere, which will ultimately form the anterior end of the temporal lobe. [WP,unvetted]." [Wikipedia:Rhinal_sulcus] subset: uberon_slim synonym: "rhinal fissure" EXACT [FMA:83746] synonym: "fissura rhinalis" EXACT [NIF_GrossAnatomy:birnlex_1368] synonym: "sulcus rhinalis" EXACT [NIF_GrossAnatomy:birnlex_1368] synonym: "rhinal fissuer (turner, rezius)" EXACT [NIF_GrossAnatomy:birnlex_1368] xref: FMA:83746 ! Rhinal sulcus xref: NIF_GrossAnatomy:birnlex_1368 ! Rhinal sulcus xref: BM:Tel-Cx-RS ! rhinal sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279357002 ! Entire rhinal sulcus synonym: "sulcus rhinalis; fissura rhinalis" RELATED LATIN [Wikipedia:Rhinal_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/c/ce/Gehirn,_basal_-_beschriftet_lat.svg [Term] id: UBERON:0002685 name: anteroventral nucleus synonym: "anterior ventral nucleus of thalamus" EXACT [FMA:62143] synonym: "anteroprincipal thalamic nucleus" EXACT [FMA:62143] synonym: "anteroventral nucleus of thalamus" EXACT [FMA:62143] synonym: "anteroventral thalamic nucleus" EXACT [FMA:62143] synonym: "anteroventral nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_1372] synonym: "nucleus anterior thalami ventralis" EXACT [NIF_GrossAnatomy:birnlex_1372] synonym: "nucleus anterior ventralis" EXACT [NIF_GrossAnatomy:birnlex_1372] synonym: "nucleus anteroinferior" EXACT [NIF_GrossAnatomy:birnlex_1372] synonym: "nucleus anteroventralis" EXACT [NIF_GrossAnatomy:birnlex_1372] synonym: "nucleus anteroventralis thalami" EXACT [NIF_GrossAnatomy:birnlex_1372] synonym: "nucleus thalamicus anteroprincipalis" EXACT [NIF_GrossAnatomy:birnlex_1372] synonym: "nucleus thalamicus anteroventralis" EXACT [NIF_GrossAnatomy:birnlex_1372] xref: FMA:62143 ! Anteroventral nucleus xref: NIF_GrossAnatomy:birnlex_1372 ! Anteroventral nucleus xref: EV:0100199 ! anterior ventral thalamic nucleus (also: UBERON:0002637 'ventral anterior nucleus') xref: ABA:AV ! Anteroventral nucleus of thalamus xref: BM:Die-AV ! anteroventral nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002679 {source="ABA"} ! anterodorsal nucleus relationship: spatially_disjoint_from UBERON:0002681 {source="ABA"} ! anteromedial nucleus relationship: spatially_disjoint_from UBERON:0002984 {source="ABA"} ! lateral dorsal nucleus xref: SCTID:279130009 ! Entire anteroventral nucleus of thalamus [Term] id: UBERON:0002686 name: angular gyrus def: "The angular gyrus is a region of the brain in the parietal lobe, that lies near the superior edge of the temporal lobe, and immediately posterior to the supramarginal gyrus; it is involved in a number of processes related to language, mathematics and cognition. It is Brodmann area 39 of the human brain. [WP,unvetted]." [Wikipedia:Angular_gyrus] subset: uberon_slim synonym: "middle part of inferior parietal lobule" EXACT [FMA:61898] synonym: "preoccipital gyrus" EXACT [FMA:61898] xref: FMA:61898 ! Angular gyrus xref: NIF_GrossAnatomy:birnlex_1376 ! Angular gyrus xref: ncithesaurus:Angular_Gyrus ! Angular Gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001872 ! parietal lobe xref: SCTID:279186009 ! Entire angular gyrus synonym: "gyrus angularis" RELATED LATIN [Wikipedia:Angular_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/8/86/Surfacegyri.JPG xref: UMLS:C0152305 [Term] id: UBERON:0002687 name: area X synonym: "anteromedial part of ventral lateral posterior nucleus (jones)" EXACT [] synonym: "area x of olszewski" EXACT [NIF_GrossAnatomy:birnlex_1379] synonym: "nucleus lateralis intermedius mediodorsalis situs ventralis medialis" EXACT [NIF_GrossAnatomy:birnlex_1379] synonym: "nucleus ventralis oralis, pars posterior (dewulf)" EXACT [NIF_GrossAnatomy:birnlex_1379] synonym: "nucleus ventrooralis internus (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1379] synonym: "nucleus ventrooralis internus, superior part" EXACT [NIF_GrossAnatomy:birnlex_1379] xref: FMA:62198 ! Area X xref: NIF_GrossAnatomy:birnlex_1379 ! Area X is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001925 ! ventral lateral nucleus [Term] id: UBERON:0002689 name: supraoptic crest def: "one of the circumventricular organs of the brain. The OVLT is outside the blood brain barrier, and so neurons in this region can respond to factors that are present in the systemic circulation." [Wikipedia:Organum_vasculosum_of_the_lamina_terminalis, https://sourceforge.net/tracker/?func=detail&aid=3474225&group_id=76834&atid=1205376] comment: AO notes: NIF has two classes here synonym: "vascular organ of lamina terminalis" EXACT [FMA:62315] synonym: "prechiasmatic gland" EXACT [NIF_GrossAnatomy:birnlex_1400] synonym: "organum vasculosum lamina terminalis" EXACT [NIF_GrossAnatomy:nlx_anat_100313] synonym: "organum vasculosum laminae terminalis" EXACT LATIN [FMA:TA] xref: FMA:62315 ! Supraoptic crest xref: NIF_GrossAnatomy:birnlex_1400 ! Supraoptic crest xref: NIF_GrossAnatomy:nlx_anat_100313 ! Organum vasculosum lamina terminalis xref: ABA:OV ! Vascular organ of the lamina terminalis xref: MA:0003018 ! supraoptic crest is_a: UBERON:0010135 {source="MA"} ! sensory circumventricular organ relationship: part_of UBERON:0002550 {source="FMA"} ! anterior hypothalamic regio relationship: superficial_to UBERON:0000201 {source="Wikipedia"} ! endothelial blood brain barrier relationship: spatially_disjoint_from UBERON:0002690 {source="ABA"} ! anteroventral periventricular nucleus relationship: spatially_disjoint_from UBERON:0001934 {source="ABA"} ! dorsomedial nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002625 {source="ABA"} ! median preoptic nucleus relationship: spatially_disjoint_from UBERON:0007626 {source="ABA"} ! subparaventricular zone relationship: spatially_disjoint_from UBERON:0002034 {source="ABA"} ! suprachiasmatic nucleus relationship: spatially_disjoint_from UBERON:0002219 {source="ABA"} ! subfornical organ synonym: "organum vasculosum laminae terminalis" EXACT LATIN [FMA:TA, FMA:62315] [Term] id: UBERON:0001929 name: supraoptic nucleus def: "The supraoptic nucleus (SON) is a nucleus of magnocellular neurosecretory cells in the hypothalamus of the mammalian brain. The nucleus is situated at the base of the brain, adjacent to the optic chiasm. In humans, it contains about 3,000 neurons. [WP,unvetted]." [Wikipedia:Supraoptic_nucleus, https://sourceforge.net/tracker/?func=detail&aid=3474225&group_id=76834&atid=1205376] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "supra-optic nucleus" EXACT [] synonym: "supraoptic nucleus of hypothalamus" EXACT [] synonym: "nucleus supraopticus" EXACT [BTO:0002697] xref: FMA:62317 ! Supraoptic nucleus xref: GAID:646 ! supraoptic nucleu xref: MA:0000849 ! supraoptic nucleus xref: NIF_GrossAnatomy:birnlex_1411 ! Supraoptic nucleus xref: BTO:0002697 ! supraoptic nucleus xref: EFO:0002476 ! supraoptic nucleus xref: http://upload.wikimedia.org/wikipedia/en/thumb/d/d7/SONss.jpg/200px-SONss.jpg xref: MESH:A08.186.211.730.385.357.342.650 ! supraoptic nucleu xref: EV:0100227 ! supraoptic nucleus xref: ABA:SO ! Supraoptic nucleus xref: BM:Die-Hy-SON ! supraoptic nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002550 {source="FMA"} ! anterior hypothalamic region relationship: part_of UBERON:0002271 {source="MA", source="ABA"} ! periventricular zone of hypothalamus relationship: capable_of GO:0030103 {source="Wikipedia"} ! vasopressin secretion relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: spatially_disjoint_from UBERON:0001932 {source="ABA"} ! arcuate nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0001930 {source="ABA"} ! paraventricular nucleus of hypothalamus xref: SCTID:369130007 ! Entire supraoptic nucleus synonym: "nucleus supraopticus" RELATED LATIN [Wikipedia:Supraoptic_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/SONss.jpg [Term] id: UBERON:0002690 name: anteroventral periventricular nucleus xref: FMA:62314 ! Anteroventral periventricular nucleus xref: NIF_GrossAnatomy:birnlex_1401 ! Anteroventral periventricular nucleus xref: ABA:AVPV ! Anteroventral periventricular nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0001934 {source="ABA"} ! dorsomedial nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002625 {source="ABA"} ! median preoptic nucleus relationship: spatially_disjoint_from UBERON:0002689 {source="ABA"} ! supraoptic crest relationship: spatially_disjoint_from UBERON:0007626 {source="ABA"} ! subparaventricular zone relationship: spatially_disjoint_from UBERON:0002034 {source="ABA"} ! suprachiasmatic nucleus relationship: spatially_disjoint_from UBERON:0002219 {source="ABA"} ! subfornical organ [Term] id: UBERON:0002691 name: ventral tegmental area def: "The ventral tegmentum (tegmentum is Latin for covering), better known as the ventral tegmental area (VTA), is a group of neurons located close to the midline on the floor of the midbrain. The VTA, the origin of dopaminergic cell bodies that comprise the mesocorticolimbic dopamine system, is widely implicated in the drug and natural reward circuitry of the brain, cognition, motivation, drug addiction, and several psychiatric disorders. The VTA contains neurons that project to numerous areas of the brain, from the prefrontal cortex (PFC) to the caudal brainstem and everywhere in between. [WP,unvetted]." [Wikipedia:Ventral_tegmental_area] subset: uberon_slim synonym: "ventral tegmental area of tsai" EXACT [] synonym: "ventral tegmental nucleus (tsai)" EXACT [] synonym: "ventral tegmental nucleus of tsai" EXACT [] xref: FMA:72438 ! Ventral tegmental area xref: NIF_GrossAnatomy:birnlex_1415 ! Ventral tegmental area xref: EFO:0001935 ! ventral tegmental area xref: GAID:587 ! ventral tegmental area xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b6/Gray712.png/200px-Gray712.png xref: MESH:A08.186.211.132.659.822.820 ! ventral tegmental area xref: ABA:VTA ! Ventral tegmental area xref: BM:MB-VTA ! ventral tegmental area is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus xref: http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png [Term] id: UBERON:0002693 name: occipitotemporal sulcus synonym: "inferior temporal fissure" EXACT [FMA:74518] synonym: "inferior temporal sulcus (roberts)" EXACT [] synonym: "inferior temporal sulcus (szikla)" EXACT [] synonym: "inferior temporal sulcus-2" EXACT [FMA:74518] synonym: "occipito-temporal sulcus" EXACT [FMA:74518] synonym: "third temporal sulcus" EXACT [FMA:74518] synonym: "inferior temporal fissure (crosby)" EXACT [NIF_GrossAnatomy:birnlex_1422] synonym: "lateral occipitotemporal sulcus" EXACT [NIF_GrossAnatomy:birnlex_1422] xref: FMA:74518 ! Occipitotemporal sulcus xref: NIF_GrossAnatomy:birnlex_1422 ! Occipitotemporal sulcus xref: BM:Tel-Cx-OTS ! occipito-temporal sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:369220009 ! Entire occipitotemporal sulcus [Term] id: UBERON:0011590 name: commissure of diencephalon synonym: "diencephalon commissure" EXACT [FMA:62445] intersection_of: UBERON:0001020 ! commissure intersection_of: part_of UBERON:0001894 ! diencephalon xref: FMA:62445 ! commissure of diencephalon def: "A commissure that is part of a diencephalon." [OBOL:automatic] [Term] id: UBERON:0002694 name: anterior hypothalamic commissure synonym: "anterior hypothalamic commissure (Ganser)" EXACT [FMA:62053] synonym: "anterior hypothalamic decussation of Ganser" EXACT [FMA:62053] xref: FMA:62053 ! Anterior hypothalamic commissure xref: NIF_GrossAnatomy:birnlex_1424 ! Anterior hypothalamic commissure is_a: UBERON:0001020 {source="FMA"} ! commissure relationship: part_of UBERON:0001894 ! diencephalon [Term] id: UBERON:0002695 name: parieto-occipital sulcus def: "Only a small part of the Parietooccipital Fissure (or parieto-occipital sulcus) is seen on the lateral surface of the hemisphere, its chief part being on the medial surface. The lateral part of the parietooccipital fissure (Fig. 726) is situated about 5 cm. in front of the occipital pole of the hemisphere, and measures about 1.25 cm. in length. The medial part of the parietooccipital fissure (Fig. 727) runs downward and forward as a deep cleft on the medial surface of the hemisphere, and joins the calcarine fissure below and behind the posterior end of the corpus callosum. In most cases it contains a submerged gyrus. [WP,unvetted]." [Wikipedia:Parieto-occipital_sulcus] comment: AO notes - two classes in ncit (in general ncit distinguishes between fissue and sulcus, whereas FMA treats these as exact synonyms) subset: uberon_slim synonym: "parieto-occipital fissure" EXACT [FMA:83754] synonym: "parieto-occipital incisure" EXACT [FMA:83754] synonym: "parietooccipital sulcus" EXACT [FMA:83754] synonym: "fissura parieto-occipitalis" EXACT [NIF_GrossAnatomy:birnlex_1428] synonym: "sulcus parieto-occipitalis" EXACT [NIF_GrossAnatomy:birnlex_1428] synonym: "sulcus parieto-occipitalis medialis" EXACT [NIF_GrossAnatomy:birnlex_1428] synonym: "sulcus parietoccipitalis" EXACT [NIF_GrossAnatomy:birnlex_1428] synonym: "sulcus parietooccipitalis" EXACT [NIF_GrossAnatomy:birnlex_1428] xref: FMA:83754 ! Parieto-occipital sulcus xref: NIF_GrossAnatomy:birnlex_1428 ! Parieto-occipital sulcus xref: OpenCyc:Mx4rv7l_DJwpEbGdrcN5Y29ycA xref: ncithesaurus:Parieto-occipital_Fissure ! Parieto-Occipital Fissure xref: ncithesaurus:Parieto-occipital_Sulcus ! Parieto-Occipital Sulcus xref: OpenCyc:Mx4rv7l_DJwpEbGdrcN5Y29ycA ! parieto-occipital sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5d/Gray726_parieto-occipital_sulcus.png/200px-Gray726_parieto-occipital_sulcus.png xref: BM:Tel-Cx-POS ! parieto-occipital sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279354009 ! Entire parieto-occipital fissure synonym: "sulcus parietooccipitalis, fissura parietooccipitalis" RELATED LATIN [Wikipedia:Parieto-occipital_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/5/5d/Gray726_parieto-occipital_sulcus.png xref: UMLS:C1744592 [Term] id: UBERON:0002696 name: cuneiform nucleus synonym: "parabigeminal area (mai)" EXACT [] xref: FMA:72427 ! Cuneiform nucleus xref: NIF_GrossAnatomy:birnlex_1430 ! Cuneiform nucleus xref: ABA:CUN ! Cuneiform nucleus xref: BM:MB-CNF ! cuneiform nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus [Term] id: UBERON:0002697 name: dorsal supraoptic decussation synonym: "commissure of Meynert" EXACT [] synonym: "dorsal supra-optic commissure" EXACT [FMA:62051] synonym: "dorsal supraoptic commissure" EXACT [FMA:62051] synonym: "dorsal supraoptic commissure (of ganser)" EXACT [] synonym: "dorsal supraoptic decussation of Meynert" EXACT [] synonym: "ganser's commissure" EXACT [FMA:62051] synonym: "Meynert's commissure" EXACT [FMA:62051] synonym: "supraoptic commissure of Meynert" EXACT [] synonym: "supraoptic commissures, dorsal" EXACT [FMA:62051] synonym: "dorsal supraoptic decussation (of ganser)" EXACT [NIF_GrossAnatomy:birnlex_1433] synonym: "dorsal supraoptic decussation (of Meynert)" EXACT [NIF_GrossAnatomy:birnlex_1433] xref: FMA:62051 ! Dorsal supraoptic decussation xref: NIF_GrossAnatomy:birnlex_1433 ! Dorsal supraoptic decussation is_a: UBERON:0001020 ! commissure synonym: "commissura supraoptica dorsalis" EXACT LATIN [FMA:TA, FMA:62051] [Term] id: UBERON:0002698 name: preoccipital notch synonym: "occipital notch" EXACT [FMA:83739] synonym: "preoccipital incisura" EXACT [FMA:83739] synonym: "preoccipital incisure" EXACT [FMA:83739] synonym: "incisura praeoccipitalis" EXACT [NIF_GrossAnatomy:birnlex_1436] synonym: "incisura preoccipitalis" EXACT [NIF_GrossAnatomy:birnlex_1436] synonym: "incisura parieto-occipitalis" EXACT [NIF_GrossAnatomy:birnlex_1436] xref: FMA:83739 ! Preoccipital notch xref: NIF_GrossAnatomy:birnlex_1436 ! Preoccipital notch is_a: UBERON:0000464 ! anatomical space xref: SCTID:369229005 ! Entire preoccipital notch [Term] id: UBERON:0002699 name: supraopticohypophysial tract synonym: "supra-opticohypophysial tract" EXACT [FMA:62054] synonym: "supraopticohypophyseal tract" EXACT [FMA:62054] xref: FMA:62054 ! Supraopticohypophysial tract xref: NIF_GrossAnatomy:birnlex_1440 ! Supraopticohypophysial tract is_a: UBERON:0002316 ! white matter of neuraxis synonym: "tractus supraopticohypophysialis" EXACT LATIN [FMA:TA, FMA:62054] [Term] id: UBERON:0002700 name: subcuneiform nucleus synonym: "subcuneiform area of midbrain" EXACT [FMA:72428] xref: FMA:72428 ! Subcuneiform nucleus xref: NIF_GrossAnatomy:birnlex_1441 ! Subcuneiform nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002701 name: anterior median oculomotor nucleus synonym: "anterior median nucleus of oculomotor nerve" EXACT [FMA:72423] xref: FMA:72423 ! Anterior median oculomotor nucleus xref: NIF_GrossAnatomy:birnlex_1445 ! Anterior median oculomotor nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002702 name: middle frontal gyrus def: "The middle frontal gyrus makes up about one-third of the frontal lobe of the human brain. (A gyrus is one of the prominent 'bumps' or 'ridges' on the surface of the human brain. ) The middle frontal gyrus, like the inferior frontal gyrus and the superior frontal gyrus, is more of a region than a true gyrus. The borders of the middle frontal gyrus are the inferior frontal sulcus below; the superior frontal sulcus above; and the precentral sulcus behind. [WP,unvetted]." [Wikipedia:Middle_frontal_gyrus] subset: uberon_slim synonym: "intermediate frontal gyrus" EXACT [FMA:61859] synonym: "medial frontal gyrus" EXACT [FMA:61859] xref: FMA:61859 ! Middle frontal gyrus xref: NIF_GrossAnatomy:birnlex_1451 ! Middle frontal gyrus xref: ncithesaurus:Middle_Frontal_Gyrus ! Middle Frontal Gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7f/Middle_frontal_gyrus.png/200px-Middle_frontal_gyrus.png xref: BTO:0004834 ! middle frontal gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001870 ! frontal lobe synonym: "gyrus frontalis medialis" EXACT LATIN [FMA:TA, FMA:61859] xref: SCTID:362332009 ! Entire middle frontal gyrus synonym: "gyrus frontalis medius" RELATED LATIN [Wikipedia:Middle_frontal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/7/7f/Middle_frontal_gyrus.png [Term] id: UBERON:0002703 name: precentral gyrus def: "The primary motor cortex (or M1) is a brain region that in humans is located in the posterior portion of the frontal lobe. It works in association with pre-motor areas to plan and execute movements. M1 contains large neurons known as Betz cells which send long axons down the spinal cord to synapse onto alpha motor neurons which connect to the muscles. Pre-motor areas are involved in planning actions (in concert with the basal ganglia) and refining movements based upon sensory input (this requires the cerebellum). [WP,unvetted]." [Wikipedia:Precentral_gyrus] subset: uberon_slim synonym: "precentral convolution" EXACT [FMA:61894] synonym: "prerolandic gyrus" EXACT [FMA:61894] xref: FMA:61894 ! Precentral gyrus xref: NIF_GrossAnatomy:birnlex_1455 ! Precentral gyrus xref: ncithesaurus:Precentral_Gyrus ! Precentral Gyrus xref: EFO:0001373 ! precentral gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/eb/Ba4.png/200px-Ba4.png is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001870 ! frontal lobe xref: UMLS:C0152299 [Term] id: UBERON:0002704 name: metathalamus def: "The metathalamus is a composite structure of the thalamus, consisting of the medial geniculate nucleus and the lateral geniculate nucleus. [WP,unvetted]." [Wikipedia:Metathalamus] comment: note we follow FMA in making this a subtype of nucleus, but in fact it is a group containing two nuclei subset: uberon_slim synonym: "geniculate group of the dorsal thalamus" EXACT [FMA:62023] synonym: "nuclei metathalami" EXACT [NIF_GrossAnatomy:birnlex_1461] xref: FMA:62023 ! Metathalamus xref: NIF_GrossAnatomy:birnlex_1461 ! Metathalamus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: EV:0100217 ! metathalamus xref: ABA:GENd ! Geniculate group, dorsal thalamus xref: MA:0000868 ! geniculate thalamic group is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0004703 {source="MA"} ! dorsal thalamus relationship: spatially_disjoint_from UBERON:0002144 {source="ABA"} ! peripeduncular nucleus relationship: spatially_disjoint_from UBERON:0002776 {source="ABA"} ! ventral nuclear group xref: SCTID:361550004 ! Entire metathalamus synonym: "corpora geniculata" RELATED LATIN [Wikipedia:Metathalamus] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png synonym: "geniculate thalamic group" EXACT [MA:0000868] [Term] id: UBERON:0002706 name: posterior nucleus of hypothalamus synonym: "posterior hypothalamic area" EXACT [FMA:62350] synonym: "posterior hypothalamic nucleus" EXACT [FMA:62350] synonym: "nucleus posterior hypothalami" RELATED [BTO:0002461] xref: FMA:62350 ! Posterior nucleus of hypothalamus xref: NIF_GrossAnatomy:birnlex_1463 ! Posterior nucleus of hypothalamus xref: BTO:0002461 ! posterior hypothalamic nucleus xref: EV:0100235 ! posterior nucleus (also: UBERON:0002866 'caudal part of spinal trigeminal nucleus') xref: ABA:PH ! Posterior hypothalamic nucleus xref: BM:Die-Hy-HPA ! posterior hypothalamic area is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002634 {source="ABA"} ! anterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002206 {source="ABA"} ! mammillary body relationship: spatially_disjoint_from UBERON:0002035 {source="ABA"} ! medial preoptic nucleus relationship: spatially_disjoint_from UBERON:0001935 {source="ABA"} ! ventromedial nucleus of hypothalamus synonym: "area hypothalamica posterior" EXACT LATIN [FMA:TA, FMA:62350] xref: SCTID:362385002 ! Entire caudal area of hypothalamus [Term] id: UBERON:0002707 name: pyramidal tract def: "The corticospinal or pyramidal tract is a collection of axons that travel between the cerebral cortex of the brain and the spinal cord. The corticospinal tract mostly contains motor axons. It actually consists of two separate tracts in the spinal cord: the lateral corticospinal tract and the medial corticospinal tract. An understanding of these tracts leads to an understanding of why for the most part, one side of the body is controlled by the opposite side of the brain. Also the corticobulbar tract is considered to be a pyramidal tract. The corticobulbar tract carries signals that control motor neurons located in cranial nerve brain nuclei rather than motor neurons located in the spinal cord. The neurons of the pyramidal tracts are pyramidal neurons, but that is not how the pyramidal tract got its name, as most of the pyramidal neurons send their axons elsewhere. Instead, it got its name from the shape of the corticospinal axon tracts: when the pyramidal tract passes the medulla, it forms a dense bundle of nerve fibres that is shaped somewhat like a pyramid. [WP,unvetted]." [Wikipedia:Pyramidal_tract] subset: uberon_slim xref: FMA:72634 ! Pyramidal tract xref: NIF_GrossAnatomy:birnlex_1464 ! Pyramidal tract xref: GAID:702 ! pyramidal tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ac/Gray684.png/200px-Gray684.png xref: MESH:A08.186.854.633 ! pyramidal tract xref: BM:Me-PyT ! pyramidal tract is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:362325000 ! Entire pyramidal tract [Term] id: UBERON:0002708 name: posterior periventricular nucleus synonym: "periventricular nucleus, posterior subdivision" EXACT [FMA:62349] synonym: "posterior periventricular nucleus" EXACT [FMA:62349] synonym: "posterior periventricular nucleus of hypothalamus" EXACT [FMA:62349] synonym: "posterior periventricular hypothalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_1466] synonym: "nucleus periventricularis posterior" RELATED [BTO:0002479] xref: FMA:62349 ! Posterior periventricular nucleus of hypothalamus xref: NIF_GrossAnatomy:birnlex_1466 ! Posterior periventricular nucleus xref: BTO:0002479 ! posterior periventricular nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002709 name: posterior nuclear complex subset: vertebrate_core synonym: "posterior complex of thalamus" EXACT [FMA:62024] synonym: "posterior nuclear complex" EXACT [FMA:62024] synonym: "posterior nuclear complex of thalamus" EXACT [FMA:62024] synonym: "posterior thalamic nuclear group" EXACT [FMA:62024] synonym: "posterior nuclear group of thalamus" EXACT [FMA:62024] synonym: "nuclei posteriores thalami" EXACT [NIF_GrossAnatomy:birnlex_1467] synonym: "posterior thalamic nucleus" RELATED [BTO:0002462] xref: FMA:62024 ! Posterior nuclear group of thalamus xref: NIF_GrossAnatomy:birnlex_1467 ! Posterior nuclear complex xref: BTO:0002462 ! posterior nuclear complex of thalamus xref: ZFA:0000325 ! caudal thalamic nucleus (also: UBERON:0003030 'posterior nucleus of thalamus') xref: ABA:PO ! Posterior complex of the thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001897 ! thalamus relationship: spatially_disjoint_from UBERON:0002983 {source="ABA"} ! lateral posterior nucleus relationship: spatially_disjoint_from UBERON:0003033 {source="ABA"} ! suprageniculate nucleus xref: SCTID:424395006 ! Entire nucleus of posterior nuclear group of thalamus xref: TAO:0000325 ! caudal thalamic nucleus (also: UBERON:0003030 'posterior nucleus of thalamus') synonym: "caudal thalamic nucleus" RELATED [TAO:0000325] [Term] id: UBERON:0002710 name: cingulate sulcus def: "The cingulate sulcus is a sulcus (brain fold) on the medial wall of the cerebral cortex. The frontal and parietal lobes are separated by the cingulate sulcus from the cingulate gyrus. [WP,unvetted]." [Wikipedia:Cingulate_sulcus] subset: uberon_slim synonym: "calloso-marginal sulcus" EXACT [FMA:83748] synonym: "callosomarginal fissure" EXACT [FMA:83748] synonym: "callosomarginal sulcus" EXACT [FMA:83748] synonym: "cingulate fissure" EXACT [FMA:83748] synonym: "sulcus callosomarginalis" EXACT [NIF_GrossAnatomy:birnlex_1468] synonym: "sulcus cingulatus" EXACT [NIF_GrossAnatomy:birnlex_1468] synonym: "sulcus cinguli" EXACT [NIF_GrossAnatomy:birnlex_1468] xref: FMA:83748 ! Cingulate sulcus xref: NIF_GrossAnatomy:birnlex_1468 ! Cingulate sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Gray727_cingulate_sulcus.svg/200px-Gray727_cingulate_sulcus.svg.png xref: BM:Tel-Cx-CGS ! cingulate sulcus is_a: UBERON:0000093 ! sulcus relationship: adjacent_to UBERON:0002967 ! cingulate gyrus xref: SCTID:279350000 ! Entire cingulate sulcus synonym: "sulcus cinguli" RELATED LATIN [Wikipedia:Cingulate_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/2/2e/Gray727_cingulate_sulcus.svg [Term] id: UBERON:0002711 name: nucleus of posterior commissure synonym: "posterior commissure nucleus" EXACT [FMA:68463] xref: FMA:68463 ! Nucleus of posterior commissure xref: NIF_GrossAnatomy:birnlex_1470 ! Nucleus of posterior commissure xref: ABA:NPC ! Nucleus of the posterior commissure xref: BM:NPC ! nucleus of posterior commissure is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002996 {source="ABA"} ! nucleus of optic tract relationship: spatially_disjoint_from UBERON:0002565 {source="ABA"} ! olivary pretectal nucleus relationship: spatially_disjoint_from UBERON:0006848 {source="ABA"} ! posterior pretectal nucleus [Term] id: UBERON:0002712 ! premammillary nucleus name: premammillary nucleus synonym: "premammillary nuclei" EXACT [FMA:62348] xref: FMA:62348 ! Premammillary nucleus xref: NIF_GrossAnatomy:birnlex_1473 ! Premammillary nucleus is_a: UBERON:0006568 {source="FMA"} ! hypothalamic nucleus relationship: part_of UBERON:0002770 {source="FMA"} ! posterior hypothalamic region [Term] id: UBERON:0007767 name: dorsal premammillary nucleus xref: FMA:77006 ! dorsal premammillary nucleus xref: ABA:PMd ! Dorsal premammillary nucleus is_a: UBERON:0002712 ! premammillary nucleus relationship: spatially_disjoint_from UBERON:0002634 {source="ABA"} ! anterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002206 {source="ABA"} ! mammillary body relationship: spatially_disjoint_from UBERON:0002035 {source="ABA"} ! medial preoptic nucleus relationship: spatially_disjoint_from UBERON:0002706 {source="ABA"} ! posterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0007768 {source="ABA"} ! ventral premammillary nucleus [Term] id: UBERON:0007768 name: ventral premammillary nucleus xref: FMA:77007 ! ventral premammillary nucleus xref: ABA:PMv ! Ventral premammillary nucleus is_a: UBERON:0002712 ! premammillary nucleus relationship: spatially_disjoint_from UBERON:0002634 {source="ABA"} ! anterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002206 {source="ABA"} ! mammillary body relationship: spatially_disjoint_from UBERON:0002035 {source="ABA"} ! medial preoptic nucleus relationship: spatially_disjoint_from UBERON:0002706 {source="ABA"} ! posterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0007767 {source="ABA"} ! dorsal premammillary nucleus [Term] id: UBERON:0002713 name: circular sulcus of insula def: "A marginal sulcus that is part of a insula [Automatically generated definition]." [OBOL:automatic] synonym: "circular fissure" EXACT [FMA:83753] synonym: "circular sulcus (of reil)" EXACT [] synonym: "circuminsular sulcus" EXACT [FMA:83753] synonym: "limiting fissure" EXACT [FMA:83753] synonym: "marginal sulcus of insula" EXACT [FMA:83753] synonym: "central lobe marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "central lobe marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "central lobe marginal sulcus" EXACT [OBOL:automatic] synonym: "cortex of island marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "cortex of island marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "cortex of island marginal sulcus" EXACT [OBOL:automatic] synonym: "insula lobule marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insula lobule marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insula lobule marginal sulcus" EXACT [OBOL:automatic] synonym: "insula marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insula marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insula marginal sulcus" EXACT [OBOL:automatic] synonym: "insular cortex marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insular cortex marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insular cortex marginal sulcus" EXACT [OBOL:automatic] synonym: "insular lobe marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insular lobe marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insular lobe marginal sulcus" EXACT [OBOL:automatic] synonym: "insular region marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insular region marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "insular region marginal sulcus" EXACT [OBOL:automatic] synonym: "island of reil marginal branch of cingulate sulcus" EXACT [OBOL:automatic] synonym: "island of reil marginal ramus of cingulate sulcus" EXACT [OBOL:automatic] synonym: "island of reil marginal sulcus" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of central lobe" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of cortex of island" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of insula" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of insula lobule" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of insular cortex" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of insular lobe" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of insular region" EXACT [OBOL:automatic] synonym: "marginal branch of cingulate sulcus of island of reil" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of central lobe" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of cortex of island" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of insula" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of insula lobule" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of insular cortex" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of insular lobe" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of insular region" EXACT [OBOL:automatic] synonym: "marginal ramus of cingulate sulcus of island of reil" EXACT [OBOL:automatic] synonym: "marginal sulcus of central lobe" EXACT [OBOL:automatic] synonym: "marginal sulcus of cortex of island" EXACT [OBOL:automatic] synonym: "marginal sulcus of insula lobule" EXACT [OBOL:automatic] synonym: "marginal sulcus of insular cortex" EXACT [OBOL:automatic] synonym: "marginal sulcus of insular lobe" EXACT [OBOL:automatic] synonym: "marginal sulcus of insular region" EXACT [OBOL:automatic] synonym: "marginal sulcus of island of reil" EXACT [OBOL:automatic] synonym: "sulcus circularis insulae" EXACT [NIF_GrossAnatomy:birnlex_1475] synonym: "sulcus marginalis insulae" EXACT [NIF_GrossAnatomy:birnlex_1475] synonym: "ciruclar insular sulcus" EXACT [NIF_GrossAnatomy:birnlex_1475] synonym: "marginal insular sulcus" EXACT [NIF_GrossAnatomy:birnlex_1475] xref: FMA:83753 ! Circular sulcus of insula xref: NIF_GrossAnatomy:birnlex_1475 ! Circular sulcus of insula is_a: UBERON:0002912 ! marginal sulcus intersection_of: UBERON:0002912 ! marginal sulcus intersection_of: part_of UBERON:0002022 ! insula [Term] id: UBERON:0002714 name: rubrospinal tract def: "long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord[GO]." [Wikipedia:Rubrospinal_tract] subset: uberon_slim synonym: "monakow's tract" EXACT [FMA:72640] synonym: "rubrospinal tract (monakow)" EXACT [NIF_GrossAnatomy:birnlex_1476] xref: FMA:72640 ! Rubrospinal tract xref: NIF_GrossAnatomy:birnlex_1476 ! Rubrospinal tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Medulla_spinalis_-_tracts_-_English.svg/200px-Medulla_spinalis_-_tracts_-_English.svg.png is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:369264001 ! Entire rubrospinal tract synonym: "tractus rubrospinalis" RELATED LATIN [Wikipedia:Rubrospinal_tract] xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg [Term] id: UBERON:0002715 name: spinal trigeminal tract of medulla xref: FMA:72625 ! Spinal trigeminal tract of medulla xref: NIF_GrossAnatomy:birnlex_1477 ! Spinal trigeminal tract of medulla is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0002716 name: collateral sulcus def: "The collateral fissure (or sulcus) is on the tentorial surface of the hemisphere and extends from near the occipital pole to within a short distance of the temporal pole. Behind, it lies below and lateral to the calcarine fissure, from which it is separated by the lingual gyrus; in front, it is situated between the hippocampal gyrus and the anterior part of the fusiform gyrus. [WP,unvetted]." [Wikipedia:Collateral_fissure] comment: AO notes: cnit has two distinct classes; FMA and NIF treat these as exact synonyms. subset: uberon_slim synonym: "collateral fissure" EXACT [FMA:83751] synonym: "sulcus collateralis" EXACT [NIF_GrossAnatomy:birnlex_1480] xref: FMA:83751 ! Collateral sulcus xref: NIF_GrossAnatomy:birnlex_1480 ! Collateral sulcus xref: ncithesaurus:Collateral_Sulcus ! Collateral Sulcus xref: ncithesaurus:Collateral_Fissure ! Collateral Fissure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/93/Gray738.png/200px-Gray738.png is_a: UBERON:0000093 ! sulcus xref: SCTID:279356006 ! Entire collateral sulcus synonym: "sulcus collateralis, fissura collateralis" RELATED LATIN [Wikipedia:Collateral_fissure] xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Gray738.png xref: UMLS:C0228226 [Term] id: UBERON:0002717 name: rostral interstitial nucleus of medial longitudinal fasciculus def: "The rostral interstitial nucleus of medial longitudinal fasciculus (riMLF) is a portion of the medial longitudinal fasciculus which controls vertical gaze. They project to the vestibular nuclei. [WP,unvetted]." [Wikipedia:Rostral_interstitial_nucleus_of_medial_longitudinal_fasciculus] subset: uberon_slim synonym: "rostral interstitial nucleus of mlf" EXACT [] xref: FMA:72433 ! Rostral interstitial nucleus of medial longitudinal fasciculus xref: NIF_GrossAnatomy:birnlex_1481 ! Rostral interstitial nucleus of medial longitudinal fasciculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/90/Gray710.png/200px-Gray710.png is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001943 ! midbrain tegmentum synonym: "nucleus interstitialis" RELATED LATIN [Wikipedia:Rostral_interstitial_nucleus_of_medial_longitudinal_fasciculus] xref: http://upload.wikimedia.org/wikipedia/commons/9/90/Gray710.png [Term] id: UBERON:0002719 name: spino-olivary tract def: "The spino-olivary tract is located in the ventral funiculus of the spinal cord. This tract carries proprioception information from muscles and tendons as well as cutaneous impulses to the olivary nucleus. [WP,unvetted]." [Wikipedia:Spino-olivary_tract] subset: uberon_slim synonym: "helweg's tract" EXACT [FMA:72643] xref: FMA:72643 ! Spino-olivary tract xref: NIF_GrossAnatomy:birnlex_1484 ! Spino-olivary tract is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception xref: SCTID:362607001 ! Entire spino-olivary tract synonym: "tractus spinoolivaris" RELATED LATIN [Wikipedia:Spino-olivary_tract] [Term] id: UBERON:0002720 name: mammillary peduncle synonym: "peduncle of mammillary body" EXACT [FMA:62061] xref: FMA:62061 ! Mammillary peduncle xref: NIF_GrossAnatomy:birnlex_1486 ! Mammillary peduncle is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0002770 {source="FMA"} ! posterior hypothalamic region xref: SCTID:369146004 ! Entire mammillary peduncle [Term] id: UBERON:0002722 name: trochlear nucleus def: "The nucleus of the trochlear nerve is located in the midbrain, at the level of the inferior colliculus. It is a motor nucleus, so located near the midline. Oddly, fibers from the trochlear nucleus cross over in the midbrain at the superior medullary velum and exit posteriorly, (this is the only cranial nerve to do so). The nerve then goes around the midbrain, and is visible coming out the sides. [WP,unvetted]." [Wikipedia:Trochlear_nucleus] subset: uberon_slim subset: vertebrate_core synonym: "fourth cranial nerve nucleus" EXACT [FMA:54518] synonym: "nucleus of trochlear nerve" EXACT [FMA:54518] synonym: "trochlear IV nucleus" EXACT [MA:0001075] synonym: "trochlear motor nucleus" EXACT [ZFA:0000450] synonym: "motor nucleus IV" EXACT [ZFA:0000450] synonym: "nIV" EXACT [ZFA:0000450] xref: FMA:54518 ! Trochlear nucleus xref: NIF_GrossAnatomy:birnlex_1488 ! Trochlear nucleus xref: ZFA:0000450 ! trochlear motor nucleus xref: MA:0001075 ! trochlear IV nucleus xref: http://upload.wikimedia.org/wikipedia/en/thumb/c/c6/Drn.png/200px-Drn.png xref: EV:0100251 ! trochlear nucleus xref: ABA:IV ! Trochlear nucleus xref: BM:MB-IV ! trochlear nucleus is_a: UBERON:0000126 ! cranial nerve nucleus relationship: continuous_with UBERON:0001644 ! trochlear nerve relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus synonym: "nucleus nervi trochlearis" EXACT LATIN [FMA:TA, FMA:54518] xref: SCTID:280163001 ! Entire trochlear nucleus xref: TAO:0000450 ! trochlear motor nucleus synonym: "nucleus nervi trochlearis" RELATED LATIN [Wikipedia:Trochlear_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Drn.png [Term] id: UBERON:0002723 name: mammillary princeps fasciculus synonym: "principal mammillary fasciculus" EXACT [FMA:62057] synonym: "principle mamillary fasciculus" EXACT [FMA:62057] synonym: "principal mammillary tract" EXACT [NIF_GrossAnatomy:birnlex_1492] xref: FMA:62057 ! Mammillary princeps fasciculus xref: NIF_GrossAnatomy:birnlex_1492 ! Mammillary princeps fasciculus is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002724 name: limen of insula synonym: "angulus gyri olfactorii lateralis" EXACT [FMA:75266] synonym: "insula limen" EXACT [FMA:75266] synonym: "gyrus ambiens (noback)" EXACT [NIF_GrossAnatomy:birnlex_1493] synonym: "limen insulae" EXACT [NIF_GrossAnatomy:birnlex_1493] xref: FMA:75266 ! Limen of insula xref: NIF_GrossAnatomy:birnlex_1493 ! Limen of insula is_a: UBERON:0000464 ! anatomical space xref: SCTID:369215009 ! Entire limen insulae [Term] id: UBERON:0002727 name: medial medullary lamina synonym: "inner medullary lamina" EXACT [FMA:62470] synonym: "internal medullary lamina of corpus striatum" EXACT [FMA:62470] synonym: "internal medullary lamina of globus pallidus" EXACT [FMA:62470] synonym: "internal medullary lamina of lentiform nucleus" EXACT [FMA:62470] synonym: "medial medullary lamina" EXACT [FMA:62470] synonym: "medial medullary lamina of corpus striatum" EXACT [FMA:62470] synonym: "medial medullary lamina of pallidum" EXACT [FMA:62470] synonym: "medial medullary stria" EXACT [FMA:62470] synonym: "medial medullary lamina of globus pallidus" EXACT [FMA:62470] xref: FMA:62470 ! Medial medullary lamina of globus pallidus xref: NIF_GrossAnatomy:birnlex_1501 ! Medial medullary lamina xref: BTO:0002251 ! lamina medullaris medialis corporis striati is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001875 ! globus pallidus synonym: "lamina medullaris interna corporis striati" EXACT LATIN [FMA:TA, FMA:62470] synonym: "lamina medullaris medialis corporis striati" EXACT LATIN [FMA:TA, FMA:62470] xref: SCTID:369205003 ! Entire medial medullary lamina [Term] id: UBERON:0002730 name: regional part of thalamus subset: non_informative def: "A regional part of brain that is part of a thalamus [Automatically generated definition]." [OBOL:automatic] synonym: "segment of thalamus" EXACT [NIF_GrossAnatomy:birnlex_1517] synonym: "thalamus segment" EXACT [FMA:67705] xref: FMA:67705 ! Segment of thalamus xref: NIF_GrossAnatomy:birnlex_1517 ! Regional part of thalamus is_a: UBERON:0002784 ! regional part of diencephalon intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001897 ! thalamus xref: SCTID:119406000 ! Thalamus part [Term] id: UBERON:0002731 name: vestibulocochlear nerve root synonym: "central part of vestibulocochlear nerve" EXACT [FMA:72499] synonym: "statoacoustic nerve fibers" EXACT [FMA:72499] synonym: "vestibulocochlear nerve fibers" EXACT [FMA:72499] synonym: "vestibulocochlear nerve roots" EXACT [FMA:72499] synonym: "vestibulocochlear nerve tract" EXACT [FMA:72499] xref: FMA:72499 ! Vestibulocochlear nerve tract xref: NIF_GrossAnatomy:birnlex_1519 ! Vestibulocochlear nerve root is_a: UBERON:0000064 ! organ part [Term] id: UBERON:0002732 name: longitudinal pontine fibers synonym: "longitudinal fasciculus of the pons" EXACT [FMA:72513] synonym: "longitudinal pontine fibers" EXACT [FMA:72513] synonym: "longitudinal pontine fibres" EXACT [FMA:72513] synonym: "longitudinal pontine tract" EXACT [FMA:72513] xref: FMA:72513 ! Longitudinal pontine tract xref: NIF_GrossAnatomy:birnlex_1523 ! Longitudinal pontine fibers is_a: UBERON:0002316 ! white matter of neuraxis synonym: "fibrae pontis longitudinales" EXACT LATIN [FMA:TA, FMA:72513] xref: SCTID:361544009 ! Entire longitudinal fasciculus of pons [Term] id: UBERON:0002733 name: intralaminar nuclear group def: "The intralaminar nucleus is a nucleus of the thalamus that contains the following nuclei: central lateral centromedian (or 'central medial') paracentral parafascicular. Some sources also include a 'central dorsal' nucleus. [WP,unvetted]." [Wikipedia:Intralaminar_thalamic_nuclei] subset: uberon_slim synonym: "intralaminar nuclear group" EXACT [FMA:62021] synonym: "intralaminar nuclei of thalamus" EXACT [FMA:62021] synonym: "intralaminar thalamic nuclei" EXACT [FMA:62021] synonym: "nonspecific thalamic system" EXACT [FMA:62021] synonym: "intralaminar nuclear group of thalamus" EXACT [FMA:62021] synonym: "nuclei intralaminares (thalami)" EXACT [NIF_GrossAnatomy:birnlex_1530] xref: FMA:62021 ! Intralaminar nuclear group of thalamus xref: NIF_GrossAnatomy:birnlex_1530 ! Intralaminar nuclear group xref: GAID:660 ! intralaminar thalamic nuclei xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Thalmus.png/200px-Thalmus.png xref: MESH:A08.186.211.730.385.826.701.460 ! intralaminar thalamic nuclei xref: ABA:ILM ! Intralaminar nuclei of the dorsal thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001897 ! thalamus relationship: spatially_disjoint_from UBERON:0001899 {source="ABA"} ! epithalamus relationship: spatially_disjoint_from UBERON:0002736 {source="ABA"} ! lateral nuclear group relationship: spatially_disjoint_from UBERON:0001903 {source="ABA"} ! thalamic reticular nucleus synonym: "nuclei intralaminares thalami" EXACT LATIN [FMA:TA, FMA:62021] xref: SCTID:279159009 ! Entire nucleus of intralaminar nuclear group of thalamus [Term] id: UBERON:0002734 name: superior temporal sulcus synonym: "parallel sulcus" EXACT [FMA:83783] synonym: "sulcus t1" EXACT [FMA:83783] synonym: "superior temporal fissure" EXACT [FMA:83783] xref: FMA:83783 ! Superior temporal sulcus xref: NIF_GrossAnatomy:birnlex_1534 ! Superior temporal sulcus xref: ncithesaurus:Superior_Temporal_Sulcus ! Superior Temporal Sulcus xref: BM:Tel-Cx-STS ! superior temporal sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279344005 ! Entire superior temporal sulcus xref: UMLS:C0228237 [Term] id: UBERON:0002735 name: transverse pontine fibers synonym: "superficial transverse fibers of pons" EXACT [FMA:72514] synonym: "transverse fibers of pons" EXACT [FMA:72514] synonym: "transverse pontine fibers" EXACT [FMA:72514] synonym: "transverse pontine fibres" EXACT [FMA:72514] synonym: "transverse pontine tract" EXACT [FMA:72514] xref: FMA:72514 ! Transverse pontine tract xref: NIF_GrossAnatomy:birnlex_1535 ! Transverse pontine fibers is_a: UBERON:0002316 ! white matter of neuraxis synonym: "fibrae pontis transversae" EXACT LATIN [FMA:TA, FMA:72514] xref: SCTID:79836003 ! Superficial transverse fibers of pons [Term] id: UBERON:0002736 name: lateral nuclear group def: "The lateral nuclear group is a collection of nuclei on the lateral side of the thalamus. According to MeSH, it consists of the following: lateral dorsal nucleus lateral posterior nucleus pulvinar [WP,unvetted]." [Wikipedia:Lateral_nuclear_group] subset: uberon_slim synonym: "lateral nuclear group" EXACT [FMA:62174] synonym: "lateral nucleus of thalamus" EXACT [FMA:62174] synonym: "lateral thalamic nuclei" EXACT [FMA:62174] synonym: "lateral nuclear group of thalamus" EXACT [FMA:62174] synonym: "lateral group of the dorsal thalamus" EXACT [NIF_GrossAnatomy:birnlex_1537] synonym: "lateral thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_1537] synonym: "nuclei laterales thalami" EXACT [NIF_GrossAnatomy:birnlex_1537] synonym: "nucleus lateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_1537] synonym: "lateral thalamic group" EXACT [MA:0000862] xref: FMA:62174 ! Lateral nuclear group of thalamus xref: NIF_GrossAnatomy:birnlex_1537 ! Lateral nuclear group xref: GAID:661 ! lateral thalamic nuclei xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: MESH:A08.186.211.730.385.826.701.485 ! lateral thalamic nuclei xref: EV:0100210 ! lateral thalamic nuclei xref: ABA:LAT ! Lateral group of the dorsal thalamus xref: MA:0000862 ! lateral thalamic group is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0000125 {source="FMA"} ! neural nucleus relationship: part_of UBERON:0004703 {source="MA"} ! dorsal thalamus relationship: spatially_disjoint_from UBERON:0001899 {source="ABA"} ! epithalamus relationship: spatially_disjoint_from UBERON:0002733 {source="ABA"} ! intralaminar nuclear group relationship: spatially_disjoint_from UBERON:0001903 {source="ABA"} ! thalamic reticular nucleus xref: SCTID:279126006 ! Entire nucleus of lateral nuclear group of thalamus xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png [Term] id: UBERON:0002738 name: isthmus of cingulate gyrus synonym: "cingulate gyrus isthmus" EXACT [FMA:62502] synonym: "isthmus of fornicate gyrus" EXACT [FMA:62502] synonym: "isthmus of limbic lobe" EXACT [FMA:62502] xref: FMA:62502 ! Isthmus of cingulate gyrus xref: NIF_GrossAnatomy:birnlex_1541 ! Isthmus of cingulate gyrus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002967 ! cingulate gyrus [Term] id: UBERON:0002739 ! medial dorsal nucleus name: medial dorsal nucleus def: "The medial dorsal nucleus (or dorsomedial nucleus of thalamus) is a large nucleus in the thalamus. It receives inputs from the Pre-Frontal Cortex and the Limbic System and in turn relays them to the Pre-Frontal Association Cortex. As a result, it plays a crucial role in attention, planning, organization, abstract thinking, multi-tasking and active memory. The connections of the medial dorsal nucleus have even been used to delineate the prefrontal cortex of the Göttingen minipig brain. By stereology the number of brain cells in the region has been estimated to around 6.43 million neurons in the adult human brain and 36.3 million glial cells, and with the newborn having quite different numbers: around 11.2 million neurons and 10.6 million glial cells. Lesions of the medial dorsal nucleus have been associated with Wernicke's encephalopathy [WP,unvetted]." [Wikipedia:Medial_dorsal_nucleus] subset: uberon_slim synonym: "dorsal medial nucleus of thalamus" EXACT [FMA:62156] synonym: "dorsomedial nuclear group" EXACT [FMA:62156] synonym: "dorsomedial nucleus" EXACT [FMA:62156] synonym: "dorsomedial nucleus of thalamus" EXACT [FMA:62156] synonym: "medial dorsal nucleus" EXACT [FMA:62156] synonym: "medial dorsal nucleus of thalamus" EXACT [FMA:62156] synonym: "medial nuclear group" EXACT [FMA:62156] synonym: "medial thalamic nuclei" EXACT [FMA:62156] synonym: "medial thalamic nucleus" EXACT [FMA:62156] synonym: "mediodorsal nucleus" EXACT [FMA:62156] synonym: "mediodorsal thalamic nucleus" EXACT [FMA:62156] synonym: "medial nuclear group of thalamus" EXACT [FMA:62156] synonym: "medial dorsal thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_1543] synonym: "nucleus dorsomedialis thalami" EXACT [NIF_GrossAnatomy:birnlex_1543] synonym: "nucleus medialis dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1543] synonym: "nucleus mediodorsalis thalami" RELATED [BTO:0002453] synonym: "mediodorsal nucleus of thalamus" EXACT [DHB:MD] xref: FMA:62156 ! Medial nuclear group of thalamus xref: NIF_GrossAnatomy:birnlex_1543 ! Medial dorsal nucleus xref: BTO:0002453 ! medial dorsal nucleus of thalamus xref: GAID:663 ! mediodorsal thalamic nucleu xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: MESH:A08.186.211.730.385.826.701.490 ! mediodorsal thalamic nucleu xref: EV:0100200 ! medial thalamic nuclei xref: ABA:MD ! Mediodorsal nucleus of thalamus xref: BM:Die-Th-MD ! mediodorsal nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001897 ! thalamus relationship: has_function_in GO:0007613 {source="Wikipedia"} ! memory relationship: spatially_disjoint_from UBERON:0003031 {source="ABA"} ! submedial nucleus xref: ncithesaurus:Dorsomedial_Nucleus_of_the_Thalamus ! Dorsomedial Nucleus of the Thalamus xref: SCTID:279149008 ! Entire dorsomedial nucleus of thalamus synonym: "nucleus mediodorsalis thalami" RELATED LATIN [Wikipedia:Medial_dorsal_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png xref: UMLS:C0228329 [Term] id: UBERON:0002740 name: posterior cingulate gyrus def: "The posterior cingulate cortex is the backmost part of the cingulate cortex, lying behind the anterior cingulate cortex. This is the upper part of the 'limbic lobe'. The cingulate cortex is made up of an area around the midline of the brain. Surrounding areas include the retrosplenial cortex and the precuneus. Cytoarchitectonically posterior cingulate cortex is associated with Brodmann areas 23 and 31. [WP,unvetted]." [Wikipedia:Posterior_cingulate_gyrus] subset: uberon_slim xref: FMA:61924 ! Posterior cingulate gyrus xref: NIF_GrossAnatomy:birnlex_1546 ! Posterior cingulate gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Gray727.svg/200px-Gray727.svg.png is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0002967 ! cingulate gyrus [Term] id: UBERON:0002741 name: diagonal band def: "The diagonal band of Broca consists of fibers that are said to arise in the parolfactory area, the gyrus subcallosus and the anterior perforated substance, and course backward in the longitudinal striae to the dentate gyrus and the hippocampal region. This is a cholinergic bundle of nerve fibers posterior to the anterior perforated substance. It interconnects the paraterminal gyrus in the septal area with the hippocampus and lateral olfactory area. Along with the Septum Pellucidum the Diagonal Band of Broca is believed to be involved in the generation of theta waves in the hippocampus. [WP,unvetted]." [Wikipedia:Diagonal_band_of_Broca] subset: uberon_slim synonym: "broca's diagonal band" EXACT [FMA:61973] synonym: "broca's diagonal gyrus" EXACT [FMA:61973] synonym: "diagonal band of broca" EXACT [] synonym: "diagonal gyrus" EXACT [FMA:61973] synonym: "olfactory fasciculus" EXACT [FMA:61973] synonym: "olfactory radiations of zuckerkandl" EXACT [] synonym: "band of Broca" RELATED [BTO:0002445] synonym: "bandaletta diagonalis (Broca)" RELATED [BTO:0002445] synonym: "stria diagonalis" RELATED [BTO:0002445] synonym: "stria diagonalis (Broca)" RELATED [BTO:0002445] xref: FMA:61973 ! Diagonal band xref: NIF_GrossAnatomy:birnlex_1551 ! Diagonal band xref: BTO:0002445 ! diagonal band xref: GAID:684 ! diagonal band of broca xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d7/Gray724.png/200px-Gray724.png xref: MESH:A08.186.211.730.885.380 ! diagonal band of broca is_a: UBERON:0002316 ! white matter of neuraxis synonym: "stria diagonalis" RELATED LATIN [Wikipedia:Diagonal_band_of_Broca] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray724.png [Term] id: UBERON:0002742 name: lamina of septum pellucidum def: "One of two layers of both white and gray matter of the septum pellucidum. During fetal development there is a space between the two laminae called the cavum septum pellucidum which, in ninety per cent of cases, disappears during infancy." [Wikipedia:Septum_pellucidum#Layers] comment: editor note synonym: "septum pellucidum lamina" EXACT [FMA:62472] synonym: "laminae septi pellucidi" EXACT PLURAL [] xref: FMA:62472 ! Lamina of septum pellucidum xref: NIF_GrossAnatomy:birnlex_1554 ! Lamina of septum pellucidum is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0004714 {source="FMA"} ! septum pellucidum xref: SCTID:12164006 ! Lamina septum pellucidum [Term] id: UBERON:0009857 name: cavum septum pellucidum def: "Space enclosed within the laminae of the septum pelludicum, the membranous partition that seperates the frontal horns of the ventricle. contains cerebrospinal fluid (CSF) that filters from the ventricles through the septal laminae. bounded anteriorly by the genu of the corpus callosum; superiorly by the body of the corpus callosum; posteriorly by the anterior limb and pillars of the fornix; inferiorly by the anterior commissure and the rostrum of the corpus callosum; and laterally by the leaflets of the septum pellucidum. In humans, present in 100% of fetuses, but over 85% of them fuse by 3–6 months after birth." [BTO:0003447, Wikipedia:Cave_of_septum_pellucidum] synonym: "cavum of septum pellucidum" EXACT [FMA:61874] synonym: "cavum septi pellucidi" RELATED [Wikipedia:Cave_of_septum_pellucidum] synonym: "fifth ventricle" RELATED [FMA:61874, Wikipedia:Cave_of_septum_pellucidum] synonym: "septum pellucidum cave" EXACT [FMA:61874] synonym: "ventriculus septi pellucidi" EXACT [FMA:61874] synonym: "cave of septum pellucidum" EXACT [FMA:61874] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0004714 ! septum pellucidum relationship: part_of UBERON:0004714 ! septum pellucidum xref: FMA:61874 ! cave of septum pellucidum xref: BTO:0003447 ! cavum septum pellucidum xref: ncithesaurus:Fifth_Ventricle ! Fifth Ventricle xref: SCTID:180933005 ! Fifth ventricle synonym: "cavum septi pellucidi" RELATED LATIN [Wikipedia:Cave_of_septum_pellucidum] xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/CavumSeptumPellucidumDiagram.jpg xref: UMLS:C0228158 [Term] id: UBERON:0002743 name: basal forebrain def: "The basal forebrain is a collection of structures located ventrally to the striatum. It is considered to be the major cholinergic output of the CNS. It includes a group of structures that lie near the bottom of the front of the brain, including the nucleus basalis, diagonal band of Broca, and medial septal nuclei. These structures are important in the production of acetylcholine, which is then distributed widely throughout the brain. Acetylcholine affects the ability of brain cells to transmit information to one another, and also encourages plasticity, or learning. Thus, damage to the basal forebrain can reduce the amount of acetylcholine in the brain and impair learning. This may be one reason why basal forebrain damage can result in memory impairments such as amnesia and confabulation. One common cause of basal forebrain damage is aneurysm of the anterior communicating artery. Research, conducted by investigators from Children's Hospital Boston and the University of Helsinki, ties together previous observations about sleep and finds that nitric oxide production in the basal forebrain is both necessary and sufficient to produce sleep. This structure is defined, in part, as the place where adenosine acts on A1 receptors of cholinergic neurons. This results in hyperpolarization of cholinergic neurons, which inhibits the release of acetylcholine. Acetylcholine is known to promote wakefulness in the basal forebrain. Inhibition of acetylcholine release in the basal forebrain by adenosine causes slow wave sleep. The basal forebrain and adjacent areas are a focus for sleep research. Stimulating the basal forebrain gives rise to EEG sychrony and sleep. [WP,unvetted]." [Wikipedia:Basal_forebrain] subset: uberon_slim xref: FMA:77700 ! Basal forebrain xref: NIF_GrossAnatomy:birnlex_1560 ! Basal forebrain xref: BTO:0002444 ! basal forebrain xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a4/Basal_Forebrain_Monakhos_2007.png/200px-Basal_Forebrain_Monakhos_2007.png xref: BM:Tel-BF ! basal forebrain is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001890 {source="BTO"} ! forebrain synonym: "pars basalis telencephali" RELATED LATIN [Wikipedia:Basal_forebrain] xref: http://upload.wikimedia.org/wikipedia/commons/a/a4/Basal_Forebrain_Monakhos_2007.png [Term] id: UBERON:0002745 name: ventral amygdalofugal projection synonym: "ventral amygdalofugal pathway" EXACT [NIF_GrossAnatomy:birnlex_1563] xref: FMA:61977 ! Ventral amygdalofugal projection xref: NIF_GrossAnatomy:birnlex_1563 ! Ventral amygdalofugal projection is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002746 name: intermediate periventricular nucleus synonym: "intermediate periventricular nucleus of hypothalamus" EXACT [FMA:62328] synonym: "periventricular nucleus at the tuberal level" EXACT [FMA:62328] xref: FMA:62328 ! Intermediate periventricular nucleus xref: NIF_GrossAnatomy:birnlex_1564 ! Intermediate periventricular nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002747 name: neodentate part of dentate nucleus synonym: "neodentate portion of dentate nucleus" EXACT [FMA:72539] xref: FMA:72539 ! Neodentate part of dentate nucleus xref: NIF_GrossAnatomy:birnlex_1567 ! Neodentate part of dentate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002132 ! dentate nucleus [Term] id: UBERON:0002748 name: medial lemniscus of medulla def: "A medial lemniscus that is part of a medulla [Automatically generated definition]." [OBOL:automatic] synonym: "medulla medial lemniscus" EXACT [OBOL:automatic] xref: FMA:72621 ! Medial lemniscus of medulla xref: NIF_GrossAnatomy:birnlex_1570 ! Medial lemniscus of medulla is_a: UBERON:0003002 ! medial lemniscus intersection_of: UBERON:0003002 ! medial lemniscus intersection_of: part_of UBERON:0000958 ! medulla relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0002749 name: regional part of cerebellar cortex subset: non_informative def: "A regional part of brain that is part of a cerebellar cortex [Automatically generated definition]." [OBOL:automatic] synonym: "cerebellar cortical segment" EXACT [FMA:76924] synonym: "segment of cerebellar cortex" EXACT [NIF_GrossAnatomy:birnlex_1571] xref: FMA:76924 ! Segment of cerebellar cortex xref: NIF_GrossAnatomy:birnlex_1571 ! Regional part of cerebellar cortex is_a: UBERON:0002020 ! gray matter of neuraxis intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002129 ! cerebellar cortex [Term] id: UBERON:0002750 name: medial longitudinal fasciculus of medulla def: "A medial longitudinal fasciculus that is part of a medulla [Automatically generated definition]." [OBOL:automatic] synonym: "medulla medial longitudinal fasciculus" EXACT [OBOL:automatic] xref: FMA:72618 ! Medial longitudinal fasciculus of medulla xref: NIF_GrossAnatomy:birnlex_1574 ! Medial longitudinal fasciculus of medulla is_a: UBERON:0002309 ! medial longitudinal fasciculus intersection_of: UBERON:0002309 ! medial longitudinal fasciculus intersection_of: part_of UBERON:0000958 ! medulla relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0002751 name: inferior temporal gyrus def: "The inferior temporal gyrus is placed below the middle temporal sulcus, and is connected behind with the inferior occipital gyrus; it also extends around the infero-lateral border on to the inferior surface of the temporal lobe, where it is limited by the inferior sulcus. This region is one of the higher levels of the ventral stream of visual processing, associated with the representation of complex object features, such as global shape. It may also be involved in face perception. [WP,unvetted]." [Wikipedia:Inferior_temporal_gyrus] subset: uberon_slim synonym: "lateral occipitotemporal gyrus (heimer-83)" EXACT [] synonym: "gyrus temporalis inferior" EXACT [NIF_GrossAnatomy:birnlex_1577] xref: FMA:61907 ! Inferior temporal gyrus xref: NIF_GrossAnatomy:birnlex_1577 ! Inferior temporal gyrus xref: ncithesaurus:Inferior_Temporal_Gyrus ! Inferior Temporal Gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/35/Gray726.png/200px-Gray726.png xref: BM:Tel-ITG ! inferior temporal gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001871 ! temporal lobe relationship: has_function_in GO:0007601 {source="Wikipedia"} ! visual perception xref: SCTID:279191005 ! Entire inferior temporal gyrus synonym: "gyrus temporalis inferior" RELATED LATIN [Wikipedia:Inferior_temporal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Gray726.png [Term] id: UBERON:0002752 name: olivocerebellar tract def: "The olivocerebellar tract (olivocerebellar fibers) leaves the olivary nucleus and pass out through the hilum and decussate with those from the opposite olive in the raphé, then as internal arcuate fibers they pass partly through and partly around the opposite olive and enter the inferior peduncle to be distributed to the cerebellar hemisphere of the opposite side from which they arise. They terminate directly on Purkinje cells as the climbing fiber input system. [WP,unvetted]." [Wikipedia:Olivocerebellar_tract] subset: uberon_slim xref: FMA:72638 ! Olivocerebellar tract xref: NIF_GrossAnatomy:birnlex_1579 ! Olivocerebellar tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/93/Gray695.png/200px-Gray695.png is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata synonym: "t. olivocerebellaris" RELATED LATIN [Wikipedia:Olivocerebellar_tract] xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Gray695.png [Term] id: UBERON:0005413 ! spinocerebellar tract name: spinocerebellar tract def: "The spinocerebellar tract is a set of axonal fibers originating in the spinal cord and terminating in the ipsilateral cerebellum. This tract conveys information to the cerebellum about limb and joint position." [Wikipedia:Spinocerebellar_tract] xref: GAID:733 ! spinocerebellar tract xref: NIF_GrossAnatomy:nlx_anat_1005036 ! Spinocerebellar tract xref: MESH:A08.612.220.725 ! spinocerebellar tract is_a: UBERON:0002316 ! white matter of neuraxis xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg [Term] id: UBERON:0002987 name: anterior spinocerebellar tract def: "The ventral spinocerebellar tract conveys proprioceptive information from the body to the cerebellum. It is part of the somatosensory system and runs in parallel with the dorsal spinocerebellar tract. Both these tracts involve two neurons and end up on the same side of the body. The ventral tract (under L2/L3) gets its proprioceptive/fine touch/vibration information from a first order neuron, with its cell body in a dorsal ganglion. The axon runs via the fila radicularia to the dorsal horn of the grey matter. There it makes a synapse with the dendrites of two neurons: they send their axons bilaterally to the ventral border of the lateral funiculi. The ventral spinocerebellar tract then enters the cerebellum via the superior cerebellar peduncle. This is in contrast with the dorsal spinocerebellar tract (C8 - L2/L3), which only has 1 unilateral axon that has its cell body in the Clarke's nuclei (only at the level of C8 - L2/L3). The fibers of the ventral spinocerebellar tract then eventually enter the cerebellum via the superior cerebellar peduncle. This is one of the few afferent tracts through the superior cerebellar peduncle. Originates from ventral horn at lumbosacral spinal levels. Axons first cross midline in the spinal cord and run in the ventral border of the lateral funiculi. These axons ascend up to the pons where they join the superior cerebellar peduncle to enter the cerebellum. Once in the deep white matter of the cerebellum, the axons recross the midline, give off collaterals to the globose and emboliform nuclei, and terminate in the cortex of the anterior lobe and vermis of the posterior lobe. [WP,unvetted]." [Wikipedia:Ventral_spinocerebellar_tract] subset: uberon_slim synonym: "gowers' tract" EXACT [FMA:72642] synonym: "ventral spinocerebellar tract" EXACT [FMA:72642] synonym: "gower's tract" EXACT [NIF_GrossAnatomy:birnlex_848] xref: FMA:72642 ! Anterior spinocerebellar tract xref: NIF_GrossAnatomy:birnlex_848 ! Anterior spinocerebellar tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Medulla_spinalis_-_tracts_-_English.svg/200px-Medulla_spinalis_-_tracts_-_English.svg.png is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata relationship: part_of UBERON:0005413 ! spinocerebellar tract relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception xref: SCTID:369285001 ! Entire ventral spinocerebellar tract xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg [Term] id: UBERON:0002753 name: posterior spinocerebellar tract def: "The dorsal spinocerebellar tract (posterior spinocerebellar tract, Flechsig's fasciculus, Flechsig's tract) conveys proprioceptive information from the body to the cerebellum. It is part of the somatosensory system and runs in parallel with the ventral spinocerebellar tract. Proprioceptive information is taken to the via central processes of dorsal root ganglia (first order neurons). These central processes travel through the dorsal horn where they synapse with second order neurons of Clarke's nucleus. Axon fibers from Clarke's Nucleus convey this proprioceptive information in the spinal cord in the peripheral region of the posteriolateral funiculus ipsilaterally until it reaches the cerebellum, where unconscious proprioceptive information is processed. This tract involves two neurons and ends up on the same side of the body. [WP,unvetted]." [Wikipedia:Dorsal_spinocerebellar_tract] subset: uberon_slim synonym: "dorsal spinocerebellar tract" EXACT [FMA:72641] synonym: "flechsig's tract" EXACT [FMA:72641] xref: FMA:72641 ! Posterior spinocerebellar tract xref: NIF_GrossAnatomy:birnlex_1585 ! Posterior spinocerebellar tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Medulla_spinalis_-_tracts_-_English.svg/200px-Medulla_spinalis_-_tracts_-_English.svg.png xref: BM:DSCT ! dorsal spinocerebellar tract is_a: UBERON:0002316 ! white matter of neuraxis is_a: UBERON:0001018 ! axon tract relationship: part_of UBERON:0005413 ! spinocerebellar tract relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception xref: SCTID:369284002 ! Entire dorsal spinocerebellar tract xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg [Term] id: UBERON:0002640 name: cuneocerebellar tract def: "The posterior external arcuate fibers (dorsal external arcuate fibers) take origin in the gracile and cuneate nuclei; they pass to the inferior peduncle of the same side. It is uncertain whether fibers are continued directly from the gracile and cuneate fasciculi into the inferior peduncle. The term 'cuneocerebellar tract' is sometimes used to collectively refer to the posterior external arcuate fibers. [WP,unvetted]." [Wikipedia:Cuneocerebellar_tract] subset: uberon_slim synonym: "cuneocerebellar fibers" EXACT [NIF_GrossAnatomy:birnlex_1238] xref: FMA:72637 ! Cuneocerebellar tract xref: NIF_GrossAnatomy:birnlex_1238 ! Cuneocerebellar tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/98/Gray699.png/200px-Gray699.png is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0002754 name: predorsal bundle synonym: "predorsal bundle of edinger" EXACT [] synonym: "predorsal fasciculus" EXACT [FMA:72614] synonym: "tectospinal fibers" EXACT [FMA:72614] xref: FMA:72614 ! Predorsal bundle xref: NIF_GrossAnatomy:birnlex_1590 ! Predorsal bundle is_a: UBERON:0005838 ! fasciculus of brain relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0002755 name: pyramidal decussation def: "When these pyramidal fibers are traced downward, it is found that some three-fifths or more of them leave the pyramids in successive bundles, and decussate in the anterior median fissure of the medulla oblongata, forming what is termed the pyramidal decussation or motor decussation. Having crossed the middle line, they pass down in the posterior part of the lateral funiculus as the lateral cerebrospinal fasciculus. [WP,unvetted]." [Wikipedia:Decussation_of_pyramids] subset: uberon_slim synonym: "corticospinal decussation" EXACT [FMA:72633] synonym: "decussation of corticospinal tract" EXACT [FMA:72633] synonym: "decussation of pyramidal tract fibers" EXACT [FMA:72633] synonym: "decussation of pyramids" EXACT [FMA:72633] synonym: "decussation of pyramids of medulla" EXACT [FMA:72633] synonym: "motor decussation" EXACT [FMA:72633] synonym: "motor decussation of medulla" EXACT [FMA:72633] synonym: "decussation of the pyramidal tract" EXACT [NIF_GrossAnatomy:birnlex_1594] synonym: "pyramidal decussation (pourfour du petit)" EXACT [NIF_GrossAnatomy:birnlex_1594] xref: FMA:72633 ! Pyramidal decussation xref: NIF_GrossAnatomy:birnlex_1594 ! Pyramidal decussation xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ac/Gray684.png/200px-Gray684.png xref: BM:Me-PyX ! pyramidal decussation is_a: UBERON:0007418 ! decussation of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata synonym: "decussatio pyramidum medullae oblongatae" EXACT LATIN [FMA:TA, FMA:72633] synonym: "decussatio pyramidum" EXACT LATIN [FMA:TA, FMA:72633] xref: SCTID:369058001 ! Entire pyramidal decussation xref: http://upload.wikimedia.org/wikipedia/commons/a/ac/Gray684.png [Term] id: UBERON:0002756 name: anterior cingulate gyrus subset: uberon_slim xref: FMA:61916 ! Anterior cingulate gyrus xref: NIF_GrossAnatomy:birnlex_1603 ! Anterior cingulate gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/22/Gray727_anterior_cingulate_cortex.png/200px-Gray727_anterior_cingulate_cortex.png is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0002967 ! cingulate gyrus relationship: part_of UBERON:0009835 ! anterior cingulate cortex [Term] id: UBERON:0009835 ! anterior cingulate cortex name: anterior cingulate cortex def: "the frontal part of the cingulate cortex, that resembles a 'collar' form around the corpus callosum, the fibrous bundle that relays neural signals between the right and left cerebral hemispheres of the brain. It includes both the ventral and dorsal areas of the cingulate cortex, and appears to play a role in a wide variety of autonomic functions, such as regulating blood pressure and heart rate, as well as rational cognitive functions, such as reward anticipation, decision-making, empathy[1] and emotion." [Wikipedia:Anterior_cingulate_cortex] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0003027 {source="BTO"} ! cingulate cortex relationship: has_function_in GO:0002027 {source="Wikipedia"} ! regulation of heart rate xref: BTO:0004249 ! anterior cingulate cortex xref: NIF_GrossAnatomy:birnlex_936 ! Anterior cingulate cortex xref: http://upload.wikimedia.org/wikipedia/commons/2/22/Gray727_anterior_cingulate_cortex.png [Term] id: UBERON:0002757 name: regional part of epithalamus subset: non_informative def: "A regional part of brain that is part of a epithalamus [Automatically generated definition]." [OBOL:automatic] synonym: "epithalamus segment" EXACT [FMA:62013] synonym: "segment of epithalamus" EXACT [NIF_GrossAnatomy:birnlex_1607] xref: FMA:62013 ! Segment of epithalamus xref: NIF_GrossAnatomy:birnlex_1607 ! Regional part of epithalamus is_a: UBERON:0002784 ! regional part of diencephalon intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001899 ! epithalamus [Term] id: UBERON:0002758 name: dorsal nucleus of medial geniculate body synonym: "dorsal nucleus of medial geniculate complex" EXACT [FMA:62216] synonym: "medial geniculate complex, dorsal part" EXACT [NIF_GrossAnatomy:birnlex_1608] synonym: "medial geniculate nucleus, dorsal part" EXACT [NIF_GrossAnatomy:birnlex_1608] synonym: "nucleus corporis geniculati medialis, pars dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1608] synonym: "nucleus geniculatus medialis fibrosus (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1608] synonym: "nucleus geniculatus medialis pars dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1608] synonym: "nucleus dorsalis coporis geniculati medialis" RELATED [BTO:0002673] xref: FMA:62216 ! Dorsal nucleus of medial geniculate body xref: NIF_GrossAnatomy:birnlex_1608 ! Dorsal nucleus of medial geniculate body xref: BTO:0002673 ! dorsal nucleus of medial geniculate body xref: ABA:MGd ! Medial geniculate complex, dorsal part is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001927 ! medial geniculate body relationship: spatially_disjoint_from UBERON:0002759 {source="ABA"} ! magnocellular nucleus of medial geniculate body relationship: spatially_disjoint_from UBERON:0002985 {source="ABA"} ! ventral nucleus of medial geniculate body [Term] id: UBERON:0002760 name: ventral corticospinal tract def: "The anterior corticospinal tract (also called the ventral corticospinal tract, medial corticospinal tract, direct pyramidal tract, or anterior cerebrospinal fasciculus) is a small bundle of descending fibers that connect the cerebral cortex to the spinal cord. It is usually small, varying inversely in size with the lateral corticospinal tract, which is the main part of the corticospinal tract. It lies close to the anterior median fissure, and is present only in the upper part of the medulla spinalis; gradually diminishing in size as it descends, it ends about the middle of the thoracic region. It consists of descending fibers which arise from cells in the motor area of the cerebral hemisphere of the same side, and which, as they run downward in the medulla spinalis, cross in succession through the anterior white commissure to the opposite side, where they end, either directly or indirectly, by arborizing around the motor neurons in the anterior column. A few of its fibers are said to pass to the lateral column of the same side and to the gray matter at the base of the posterior column. They conduct voluntary motor impulses from the precentral gyrus to the motor centers of the cord. [WP,unvetted]." [Wikipedia:Ventral_corticospinal_tract] subset: uberon_slim synonym: "anterior corticospinal tract" EXACT [FMA:72636] synonym: "anterior pyramidal tract" EXACT [FMA:72636] synonym: "anterior tract of turck" EXACT [] synonym: "bundle of turck" EXACT [] synonym: "column of turck" EXACT [] xref: FMA:72636 ! Ventral corticospinal tract xref: NIF_GrossAnatomy:birnlex_1618 ! Ventral corticospinal tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Medulla_spinalis_-_tracts_-_English.svg/200px-Medulla_spinalis_-_tracts_-_English.svg.png is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:369092003 ! Entire ventral corticospinal tract [Term] id: UBERON:0002761 name: inferior frontal sulcus def: "The inferior frontal sulcus is a sulcus between the middle frontal gyrus and the inferior frontal gyrus. [WP,unvetted]." [Wikipedia:Inferior_frontal_sulcus] subset: uberon_slim synonym: "inferior frontal fissure" EXACT [FMA:83757] synonym: "sulcus f2" EXACT [FMA:83757] xref: FMA:83757 ! Inferior frontal sulcus xref: NIF_GrossAnatomy:birnlex_1619 ! Inferior frontal sulcus xref: ncithesaurus:Inferior_Frontal_Sulcus ! Inferior Frontal Sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279343004 ! Inferior frontal sulcus synonym: "sulcus frontalis inferior" RELATED LATIN [Wikipedia:Inferior_frontal_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/7/72/Gray726_Inferior_frontal_sulcus.svg xref: UMLS:C0262251 [Term] id: UBERON:0002762 name: internal medullary lamina of thalamus synonym: "internal medullary lamina of thalamus" EXACT [FMA:62079] synonym: "internal medullary lamina" EXACT [FMA:62079] xref: FMA:62079 ! Internal medullary lamina xref: NIF_GrossAnatomy:birnlex_1621 ! Internal medullary lamina of thalamus is_a: UBERON:0002316 ! white matter of neuraxis synonym: "lamina medullaris medialis thalami" EXACT LATIN [FMA:TA, FMA:62079] xref: SCTID:369161003 ! Entire internal medullary lamina of thalamus [Term] id: UBERON:0002763 name: accessory medullary lamina synonym: "accessory medullary lamina" EXACT [FMA:62471] synonym: "accessory medullary lamina of corpus striatum" EXACT [FMA:62471] synonym: "incomplete medullary lamina of globus pallidus" EXACT [FMA:62471] synonym: "accessory medullary lamina of globus pallidus" EXACT [FMA:62471] synonym: "accessory medullar lamina of pallidum" EXACT [NIF_GrossAnatomy:birnlex_1626] xref: FMA:62471 ! Accessory medullary lamina of globus pallidus xref: NIF_GrossAnatomy:birnlex_1626 ! Accessory medullary lamina is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001875 ! globus pallidus synonym: "lamina medullaris accessoria corporis striati" EXACT LATIN [FMA:TA, FMA:62471] [Term] id: UBERON:0002764 name: inferior precentral sulcus synonym: "inferior part of precentral fissure" EXACT [FMA:83764] synonym: "sulcus praecentralis inferior" EXACT [NIF_GrossAnatomy:birnlex_1627] synonym: "sulcus precentralis inferior" EXACT [NIF_GrossAnatomy:birnlex_1627] xref: FMA:83764 ! Inferior precentral sulcus xref: NIF_GrossAnatomy:birnlex_1627 ! Inferior precentral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002765 name: lateral medullary lamina synonym: "external medullary lamina of corpus striatum" EXACT [FMA:62469] synonym: "external medullary lamina of globus pallidus" EXACT [FMA:62469] synonym: "external medullary lamina of lentiform nucleus" EXACT [FMA:62469] synonym: "lateral medullary lamina" EXACT [FMA:62469] synonym: "lateral medullary lamina of corpus striatum" EXACT [FMA:62469] synonym: "lateral medullary lamina of pallidum" EXACT [FMA:62469] synonym: "lateral medullary stria" EXACT [FMA:62469] synonym: "outer medullary lamina" EXACT [FMA:62469] synonym: "lateral medullary lamina of globus pallidus" EXACT [FMA:62469] synonym: "external medulary lamina of globus pallidus" EXACT [NIF_GrossAnatomy:birnlex_1634] synonym: "external medulary lamina of lentiform nucleus" EXACT [NIF_GrossAnatomy:birnlex_1634] synonym: "lateral medulary lamina of globus pallidus" EXACT [NIF_GrossAnatomy:birnlex_1634] synonym: "lateral medulary stria" EXACT [NIF_GrossAnatomy:birnlex_1634] synonym: "medulary lamina of pallidum" EXACT [NIF_GrossAnatomy:birnlex_1634] synonym: "outer medulary lamina" EXACT [NIF_GrossAnatomy:birnlex_1634] xref: FMA:62469 ! Lateral medullary lamina of globus pallidus xref: NIF_GrossAnatomy:birnlex_1634 ! Lateral medullary lamina is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001875 ! globus pallidus synonym: "lamina medullaris externa corporis striati" EXACT LATIN [FMA:TA, FMA:62469] synonym: "lamina medullaris lateralis corporis striati" EXACT LATIN [FMA:TA, FMA:62469] xref: SCTID:369204004 ! Entire lateral medullary lamina [Term] id: UBERON:0002766 name: fusiform gyrus def: "The fusiform gyrus is part of the temporal lobe. It is also known as the (discontinuous) occipitotemporal gyrus. Other sources have the fusiform gyrus above the occipitotemporal gyrus and underneath the parahippocampal gyrus. [WP,unvetted]." [Wikipedia:Fusiform_gyrus] subset: uberon_slim synonym: "lateral occipitotemporal gyrus" EXACT [FMA:61908] synonym: "medial occipitotemporal gyrus-1 (heimer)" EXACT [] synonym: "occipitotemporal gyrus" EXACT [FMA:61908] xref: FMA:61908 ! Fusiform gyrus xref: NIF_GrossAnatomy:birnlex_1641 ! Fusiform gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Gray727.svg/200px-Gray727.svg.png is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001871 ! temporal lobe synonym: "gyrus occipitotemporalis lateralis" EXACT LATIN [FMA:TA, FMA:61908] xref: SCTID:110678003 ! Fusiform gyrus synonym: "gyrus fusiformis" RELATED LATIN [Wikipedia:Fusiform_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray727.svg [Term] id: UBERON:0002767 name: inferior rostral sulcus synonym: "sulcus rostralis inferior" EXACT [NIF_GrossAnatomy:birnlex_1642] xref: FMA:83767 ! Inferior rostral sulcus xref: NIF_GrossAnatomy:birnlex_1642 ! Inferior rostral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002768 name: vestibulospinal tract def: "a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord[GO]." [Wikipedia:Vestibulospinal_tract] subset: uberon_slim subset: vertebrate_core synonym: "vestibulo-spinal tract" EXACT [ZFA:0000709] xref: FMA:72646 ! Vestibulospinal tract xref: NIF_GrossAnatomy:birnlex_1643 ! Vestibulospinal tract xref: ZFA:0000709 ! vestibulo-spinal tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Medulla_spinalis_-_tracts_-_English.svg/200px-Medulla_spinalis_-_tracts_-_English.svg.png is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:369289007 ! Entire vestibulospinal tract xref: TAO:0000709 ! vestibulo-spinal tract synonym: "tractus vestibulospinalis" RELATED LATIN [Wikipedia:Vestibulospinal_tract] xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg [Term] id: UBERON:0002769 name: superior temporal gyrus def: "A gyrus (plural gyri) is a bump or ridge on the surface of the brain. The superior temporal gyrus is one of three (sometimes two) gyri in the temporal lobe of the human brain. The superior temporal gyrus is bounded by: the lateral sulcus above; the superior temporal sulcus (not always present or visible) below; an imaginary line drawn from the preoccipital notch to the lateral sulcus posteriorly. The superior temporal gyrus contains several important structures of the brain, including: Brodmann areas 41 and 42, marking the location of the primary auditory cortex, the cortical region responsible for the sensation of sound; Wernicke's area, Brodmann 22p, an important region for the processing of speech so that it can be understood as language. [WP,unvetted]." [Wikipedia:Superior_temporal_gyrus] subset: uberon_slim synonym: "gyrus temporalis superior" EXACT [NIF_GrossAnatomy:birnlex_1648] xref: FMA:61905 ! Superior temporal gyrus xref: NIF_GrossAnatomy:birnlex_1648 ! Superior temporal gyrus xref: ncithesaurus:Superior_Temporal_Gyrus ! Superior Temporal Gyrus xref: EFO:0001944 ! superior temporal gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1d/Superior_temporal_gyrus.png/200px-Superior_temporal_gyrus.png xref: BM:Tel-STG ! superior temporal gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001871 ! temporal lobe xref: SCTID:362345008 ! Entire superior temporal gyrus synonym: "gyrus temporalis superior" RELATED LATIN [Wikipedia:Superior_temporal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/1/1d/Superior_temporal_gyrus.png [Term] id: UBERON:0002770 name: posterior hypothalamic region def: "The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat." [MESH:A08.186.211.730.385.357.362] synonym: "mammillary level of hypothalamus" EXACT [FMA:62029] synonym: "mammillary region" EXACT [FMA:62029] synonym: "posterior hypothalamus" EXACT [FMA:62029] xref: FMA:62029 ! Posterior hypothalamic region xref: NIF_GrossAnatomy:birnlex_1651 ! Posterior hypothalamic region xref: GAID:651 ! posterior hypothalamus xref: MESH:A08.186.211.730.385.357.362 ! posterior hypothalamus is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001898 ! hypothalamus [Term] id: UBERON:0002771 name: middle temporal gyrus def: "Middle temporal gyrus is a gyrus in the brain on the Temporal lobe. It is located between the superior temporal gyrus and inferior temporal gyrus. Its exact function is unknown, but it has been connected with processes as different as contemplating distance, recognition of known faces, and accessing word meaning while reading. [WP,unvetted]." [Wikipedia:Middle_temporal_gyrus] subset: uberon_slim synonym: "intermediate temporal gyrus" EXACT [FMA:61906] synonym: "gyrus temporalis medius" EXACT [NIF_GrossAnatomy:birnlex_1653] synonym: "medial temporal gyrus" RELATED [Wikipedia:Middle_temporal_gyrus] xref: FMA:61906 ! Middle temporal gyrus xref: NIF_GrossAnatomy:birnlex_1653 ! Middle temporal gyrus xref: ncithesaurus:Middle_Temporal_Gyrus ! Middle Temporal Gyrus xref: EFO:0002466 ! middle temporal gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/49/WOROI_60_loc.png/200px-WOROI_60_loc.png is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001871 ! temporal lobe xref: SCTID:279190006 ! Entire middle temporal gyrus xref: http://upload.wikimedia.org/wikipedia/commons/4/49/WOROI_60_loc.png [Term] id: UBERON:0002772 name: olfactory sulcus def: "The medial orbital gyrus presents a well-marked antero-posterior sulcus, the olfactory sulcus, for the olfactory tract. [WP,unvetted]." [Wikipedia:Olfactory_sulcus] subset: uberon_slim synonym: "olfactory groove" EXACT [NIF_GrossAnatomy:birnlex_1655] synonym: "sulcus olfactorius" EXACT [NIF_GrossAnatomy:birnlex_1655] xref: FMA:83769 ! Olfactory sulcus xref: NIF_GrossAnatomy:birnlex_1655 ! Olfactory sulcus xref: ncithesaurus:Olfactory_Sulcus ! Olfactory Sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Gray729_olfactory_sulcus.png/200px-Gray729_olfactory_sulcus.png xref: BM:Tel-Cx-OFS ! orbitofrontal sulcus (also: UBERON:0002799 'fronto-orbital sulcus') is_a: UBERON:0000093 ! sulcus xref: SCTID:279358007 ! Entire olfactory sulcus synonym: "sulcus olfactorius lobi frontalis" RELATED LATIN [Wikipedia:Olfactory_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/9/9a/Gray729_olfactory_sulcus.png xref: UMLS:C0228205 [Term] id: UBERON:0002773 name: anterior transverse temporal gyrus synonym: "anterior transverse temporal convolution of heschl" EXACT [] synonym: "first transverse gyrus of heschl" EXACT [] synonym: "great transverse gyrus of heschl" EXACT [] synonym: "anterior transverse convolution of heschl" EXACT [NIF_GrossAnatomy:birnlex_1657] xref: FMA:61909 ! Anterior transverse temporal gyrus xref: NIF_GrossAnatomy:birnlex_1657 ! Anterior transverse temporal gyrus is_a: UBERON:0003939 ! transverse gyrus of Heschl xref: SCTID:279192003 ! Entire anterior transverse temporal gyrus [Term] id: UBERON:0003939 ! transverse gyrus of Heschl name: transverse gyrus of Heschl def: "the area of the temporal lobe concerned with hearing[MP]. The transverse temporal gyri (also called Heschl's gyri or Heschl's convolutions) are found in the area of primary auditory cortex in the superior temporal gyrus of the human brain, occupying Brodmann areas 41 and 42. It is the first cortical structure to process incoming auditory information. Anatomically, the transverse temporal gyri are distinct in that they run mediolaterally (towards the center of the brain) rather than dorsiventrally (front to back) as all other temporal lobe gyri run. The Heschl's gyri are named after Richard L. Heschl." [Wikipedia:Transverse_temporal_gyrus, MP:0000803] is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001871 ! temporal lobe relationship: part_of UBERON:0001393 ! auditory cortex synonym: "gyri temporales transversi" RELATED LATIN [Wikipedia:Transverse_temporal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Gray730.png [Term] id: UBERON:0002774 name: posterior transverse temporal gyrus synonym: "posterior transverse temporal convolution of heschl" EXACT [] synonym: "posterior transverse convolution of heschl" EXACT [NIF_GrossAnatomy:birnlex_1661] xref: FMA:61910 ! Posterior transverse temporal gyrus xref: NIF_GrossAnatomy:birnlex_1661 ! Posterior transverse temporal gyrus is_a: UBERON:0003939 ! transverse gyrus of Heschl xref: SCTID:279193008 ! Entire posterior transverse temporal gyrus [Term] id: UBERON:0002775 name: olivocochlear bundle synonym: "bundle of rasmussen" EXACT [] synonym: "efferent cochlear bundle" EXACT [FMA:72485] synonym: "olivocochlear bundle of rasmussen" EXACT [] synonym: "olivocochlear tract" EXACT [FMA:72485] xref: FMA:72485 ! Olivocochlear bundle xref: NIF_GrossAnatomy:birnlex_1666 ! Olivocochlear bundle is_a: UBERON:0002316 ! white matter of neuraxis synonym: "tractus olivocochlearis" EXACT LATIN [FMA:TA, FMA:72485] xref: SCTID:369030009 ! Entire tractus olivocochlearis [Term] id: UBERON:0002776 name: ventral nuclear group def: "The ventral nuclear group is a collection of nuclei on the ventral side of the thalamus. According to MeSH, it consists of the following: ventral anterior nucleus ventral lateral nucleus ventral posterior nucleus [WP,unvetted]." [Wikipedia:Ventral_nuclear_group] comment: Editors note: consider splitting nucleus from nuclear group subset: uberon_slim synonym: "ventral nuclear group" EXACT [FMA:62022] synonym: "ventral nuclear mass" EXACT [FMA:62022] synonym: "ventral nuclei of thalamus" EXACT [FMA:62022] synonym: "ventral tier thalamic nuclei" EXACT [FMA:62022] synonym: "ventral nuclear group of thalamus" EXACT [FMA:62022] synonym: "nuclei ventrales thalami" EXACT [NIF_GrossAnatomy:birnlex_1669] synonym: "ventral group of dorsal thalamus" EXACT [NIF_GrossAnatomy:birnlex_1669] xref: FMA:62022 ! Ventral nuclear group of thalamus xref: NIF_GrossAnatomy:birnlex_1669 ! Ventral nuclear group xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: BTO:0002467 ! ventral nucleus of thalamus xref: EV:0100206 ! ventral thalamic nuclei xref: ABA:VENT ! Ventral group of the dorsal thalamus xref: ZFA:0005576 ! ventral thalamus nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001897 ! thalamus relationship: spatially_disjoint_from UBERON:0002704 {source="ABA"} ! metathalamus relationship: spatially_disjoint_from UBERON:0002144 {source="ABA"} ! peripeduncular nucleus xref: SCTID:279125005 ! Entire nucleus of ventral nuclear group of thalamus xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png [Term] id: UBERON:0002780 name: regional part of forebrain subset: non_informative def: "A regional part of brain that is part of a forebrain [Automatically generated definition]." [OBOL:automatic] synonym: "forebrain segment" EXACT [FMA:61996] synonym: "segment of forebrain" EXACT [NIF_GrossAnatomy:birnlex_1677] xref: FMA:61996 ! Segment of forebrain xref: NIF_GrossAnatomy:birnlex_1677 ! Regional part of forebrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001890 ! forebrain [Term] id: UBERON:0002783 name: central tegmental tract of pons xref: FMA:72494 ! Central tegmental tract of pons xref: NIF_GrossAnatomy:birnlex_1683 ! Central tegmental tract of pons is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002784 name: regional part of diencephalon subset: non_informative def: "A regional part of brain that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "diencephalon segment" EXACT [FMA:62005] xref: FMA:62005 ! Segment of diencephalon xref: NIF_GrossAnatomy:birnlex_1685 ! Regional part of diencephalon is_a: UBERON:0002780 ! regional part of forebrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001894 ! diencephalon xref: SCTID:119264001 ! Diencephalon part [Term] id: UBERON:0002785 name: regional part of lateral hypothalamic region subset: non_informative synonym: "lateral hypothalamic region segment" EXACT [FMA:62312] synonym: "segment of lateral hypothalamic region" EXACT [NIF_GrossAnatomy:birnlex_1687] xref: FMA:62312 ! Segment of lateral hypothalamic region xref: NIF_GrossAnatomy:birnlex_1687 ! Regional part of lateral hypothalamic region intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002430 ! lateral hypothalamic area def: "A multi-tissue structure that is part of a lateral hypothalamic area." [OBOL:automatic] [Term] id: UBERON:0002786 ! abducens nerve fibers name: abducens nerve fibers synonym: "abducens nerve fibers" EXACT [FMA:72491] synonym: "central part of abducens nerve" EXACT [FMA:72491] synonym: "root of abducens nerve" EXACT [FMA:72491] synonym: "abducens nerve tract" EXACT [FMA:72491] xref: FMA:72491 ! Abducens nerve tract xref: NIF_GrossAnatomy:birnlex_1689 ! Abducens nerve fibers is_a: UBERON:0006843 {source="FMA"} ! root of cranial nerve relationship: adjacent_to UBERON:0001896 {source="ZFA-abduced"} ! medulla oblongata [Term] id: UBERON:0009908 name: caudal root of abducens nerve synonym: "radix caudalis nervi abducentis" EXACT [ZFA:0000179] xref: TAO:0000179 ! caudal root of abducens nerve is_a: UBERON:0002786 ! abducens nerve fibers relationship: part_of UBERON:0001646 {source="ZFA"} ! abducens nerve xref: ZFA:0000179 ! caudal root of abducens nerve [Term] id: UBERON:0009909 name: rostral root of abducens nerve is_a: UBERON:0002786 ! abducens nerve fibers relationship: part_of UBERON:0001646 {source="ZFA"} ! abducens nerve xref: ZFA:0000665 ! rostral root of abducens nerve xref: TAO:0000665 ! rostral root of abducens nerve [Term] id: UBERON:0002787 name: decussation of trochlear nerve synonym: "decussation of trochlear nerve (IV)" EXACT [FMA:72488] synonym: "trochlear neural decussation" EXACT [FMA:72488] xref: FMA:72488 ! Decussation of trochlear nerve xref: NIF_GrossAnatomy:birnlex_1690 ! Decussation of trochlear nerve is_a: UBERON:0007418 ! decussation of neuraxis [Term] id: UBERON:0002788 name: anterior nuclear group def: "The anterior nuclei of thalamus (or anterior nuclear group) are collection of nuclei at the rostral end of the dorsal thalamus. [WP,unvetted]." [Wikipedia:Anterior_nuclear_group] subset: uberon_slim subset: vertebrate_core synonym: "anterior nuclear group" EXACT [FMA:62019] synonym: "anterior nuclei of thalamus" EXACT [FMA:62019] synonym: "anterior nucleus of thalamus" EXACT [FMA:62019] synonym: "anterior thalamic nuclei" EXACT [FMA:62019] synonym: "anterior nuclear group of thalamus" EXACT [FMA:62019] synonym: "anterior thalamus" EXACT [NIF_GrossAnatomy:birnlex_1692] synonym: "nuclei anterior thalami" EXACT [NIF_GrossAnatomy:birnlex_1692] synonym: "nuclei anteriores (thalami)" EXACT [NIF_GrossAnatomy:birnlex_1692] synonym: "nuclei anteriores thalami" EXACT [NIF_GrossAnatomy:birnlex_1692] synonym: "nuclei thalamicus anterior" EXACT [NIF_GrossAnatomy:birnlex_1692] synonym: "anterior thalamic group" EXACT [MA:0000861] xref: FMA:62019 ! Anterior nuclear group of thalamus xref: NIF_GrossAnatomy:birnlex_1692 ! Anterior nuclear group xref: GAID:658 ! anterior thalamic nuclei xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: MESH:A08.186.211.730.385.826.701.080 ! anterior thalamic nuclei xref: ZFA:0000427 ! rostral thalamic nucleus xref: EV:0100196 ! anterior thalamic nuclei xref: MA:0000861 ! anterior thalamic group xref: ABA:ATN ! Anterior group of the dorsal thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0004703 {source="MA"} ! dorsal thalamus xref: SCTID:279124009 ! Entire nucleus of anterior nuclear group of thalamus xref: TAO:0000427 ! rostral thalamic nucleus synonym: "rostral thalamic nucleus" RELATED [TAO:0000427] [Term] id: UBERON:0002789 name: regional part of posterior hypothalamic region subset: non_informative def: "A regional part of brain that is part of a posterior hypothalamic region [Automatically generated definition]." [OBOL:automatic] synonym: "posterior hypothalamic region segment" EXACT [FMA:62311] synonym: "segment of posterior hypothalamic region" EXACT [NIF_GrossAnatomy:birnlex_1697] xref: FMA:62311 ! Segment of posterior hypothalamic region xref: NIF_GrossAnatomy:birnlex_1697 ! Regional part of posterior hypothalamic region is_a: UBERON:0003048 ! regional part of hypothalamus intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002770 ! posterior hypothalamic region [Term] id: UBERON:0002790 name: dorsal acoustic stria synonym: "posterior acoustic stria" EXACT [FMA:72496] xref: FMA:72496 ! Dorsal acoustic stria xref: NIF_GrossAnatomy:birnlex_1698 ! Dorsal acoustic stria is_a: UBERON:0002316 ! white matter of neuraxis synonym: "stria cochlearis posterior" EXACT LATIN [FMA:TA, FMA:72496] [Term] id: UBERON:0002791 name: regional part of telencephalon subset: non_informative def: "A regional part of brain that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "segment of telencephalon" EXACT [NIF_GrossAnatomy:birnlex_1700] synonym: "telencephalon segment" EXACT [FMA:62374] xref: FMA:62374 ! Segment of telencephalon xref: NIF_GrossAnatomy:birnlex_1700 ! Regional part of telencephalon is_a: UBERON:0002780 ! regional part of forebrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001893 ! telencephalon [Term] id: UBERON:0002793 name: dorsal longitudinal fasciculus of pons xref: FMA:72492 ! Dorsal longitudinal fasciculus of pons xref: NIF_GrossAnatomy:birnlex_1707 ! Dorsal longitudinal fasciculus of pons is_a: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: part_of UBERON:0000988 ! pons def: "A dorsal longitudinal fasciculus that is part of a pons." [OBOL:automatic] [Term] id: UBERON:0002794 name: medial longitudinal fasciculus of pons def: "A medial longitudinal fasciculus that is part of a pons [Automatically generated definition]." [OBOL:automatic] synonym: "medial longitudinal fasciculus of pons of varolius" EXACT [OBOL:automatic] synonym: "pons medial longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "pons of varolius medial longitudinal fasciculus" EXACT [OBOL:automatic] xref: FMA:72493 ! Medial longitudinal fasciculus of pons xref: NIF_GrossAnatomy:birnlex_1708 ! Medial longitudinal fasciculus of pons is_a: UBERON:0002309 ! medial longitudinal fasciculus intersection_of: UBERON:0002309 ! medial longitudinal fasciculus intersection_of: part_of UBERON:0000988 ! pons [Term] id: UBERON:0002796 name: motor root of trigeminal nerve comment: todo - check ZFA synonym: "motor branch of trigeminal nerve" EXACT [FMA:52612] synonym: "motor root of nervus v" EXACT [] synonym: "radix motoria (Nervus trigeminus [V])" EXACT [FMA:52612] xref: FMA:52612 ! Motor root of trigeminal nerve xref: NIF_GrossAnatomy:birnlex_1717 ! Motor root of trigeminal nerve is_a: UBERON:0004673 ! trigeminal nerve root relationship: develops_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon xref: SCTID:280189001 ! Entire motor root of trigeminal nerve xref: ZFA:0000650 ! dorsal motor root of V xref: TAO:0000650 ! dorsal motor root of V synonym: "dorsal motor root of v" RELATED [TAO:0000650] [Term] id: UBERON:0009907 name: sensory root of trigeminal nerve synonym: "radix sensoria (nervus trigeminus [v])" EXACT [FMA:52611] is_a: UBERON:0004673 {source="FMA"} ! trigeminal nerve root relationship: develops_from UBERON:0002342 {source="Wikipedia"} ! neural crest xref: FMA:52611 ! sensory root of trigeminal nerve xref: SCTID:280188009 ! Entire sensory root of trigeminal nerve [Term] id: UBERON:0002797 name: dorsal trigeminal tract def: "The dorsal trigeminal tract (dorsal trigeminothalamic tract, or lemniscus) is a tract which receives signals from Meissner's corpuscles and Pacinian corpuscles. this tract arises from Principal trigeminal nucleus and terminates in the VPM nucleus of the thalamus. [WP,unvetted]." [Wikipedia:Dorsal_trigeminal_tract] subset: uberon_slim synonym: "dorsal ascending trigeminal tract" EXACT [FMA:72500] synonym: "dorsal division of trigeminal lemniscus" EXACT [FMA:72500] synonym: "dorsal secondary ascending tract of v" EXACT [] synonym: "dorsal secondary tract of v" EXACT [] synonym: "dorsal trigeminal lemniscus" EXACT [FMA:72500] synonym: "dorsal trigeminal pathway" EXACT [FMA:72500] synonym: "dorsal trigeminothalamic tract" EXACT [FMA:72500] synonym: "posterior trigeminothalamic tract" EXACT [FMA:72500] synonym: "reticulothalamic tract" EXACT [FMA:72500] synonym: "uncrossed dorsal trigeminothalamic tract" EXACT [FMA:72500] xref: FMA:72500 ! Dorsal trigeminal tract xref: NIF_GrossAnatomy:birnlex_1718 ! Dorsal trigeminal tract is_a: UBERON:0002316 ! white matter of neuraxis synonym: "tractus trigeminothalamicus posterior" EXACT LATIN [FMA:TA, FMA:72500] [Term] id: UBERON:0002800 name: spinal trigeminal tract of pons xref: FMA:72507 ! Spinal trigeminal tract of pons xref: NIF_GrossAnatomy:birnlex_1725 ! Spinal trigeminal tract of pons is_a: UBERON:0002316 ! white matter of neuraxis xref: SCTID:369027002 ! Entire spinal trigeminal tract of pons [Term] id: UBERON:0002801 name: stratum zonale of thalamus synonym: "neuraxis stratum" EXACT [FMA:83905] synonym: "stratum zonale thalami" EXACT [NIF_GrossAnatomy:birnlex_1727] xref: FMA:83905 ! Stratum zonale of thalamus xref: NIF_GrossAnatomy:birnlex_1727 ! Stratum zonale of thalamus is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002802 name: left parietal lobe xref: FMA:72974 ! Left parietal lobe xref: NIF_GrossAnatomy:birnlex_1728 ! Left parietal lobe intersection_of: UBERON:0001872 ! parietal lobe intersection_of: part_of UBERON:0002812 ! left cerebral hemisphere relationship: adjacent_to UBERON:0002921 ! longitudinal fissure relationship: spatially_disjoint_from UBERON:0002803 ! right parietal lobe xref: SCTID:314147009 ! Entire left parietal lobe def: "A parietal lobe that is part of a left cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002803 name: right parietal lobe xref: FMA:72973 ! Right parietal lobe xref: NIF_GrossAnatomy:birnlex_1729 ! Right parietal lobe intersection_of: UBERON:0001872 ! parietal lobe intersection_of: part_of UBERON:0002813 ! right cerebral hemisphere relationship: adjacent_to UBERON:0002921 ! longitudinal fissure xref: SCTID:314146000 ! Entire right parietal lobe def: "A parietal lobe that is part of a right cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002804 name: left limbic lobe xref: FMA:72981 ! Left limbic lobe xref: NIF_GrossAnatomy:birnlex_1780 ! Left limbic lobe intersection_of: UBERON:0002600 ! limbic lobe intersection_of: part_of UBERON:0002812 ! left cerebral hemisphere def: "A limbic lobe that is part of a left cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002805 name: right limbic lobe xref: FMA:72980 ! Right limbic lobe xref: NIF_GrossAnatomy:birnlex_1781 ! Right limbic lobe intersection_of: UBERON:0002600 ! limbic lobe intersection_of: part_of UBERON:0002813 ! right cerebral hemisphere def: "A limbic lobe that is part of a right cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002806 name: left occipital lobe xref: FMA:72976 ! Left occipital lobe xref: NIF_GrossAnatomy:birnlex_1782 ! Left occipital lobe intersection_of: UBERON:0002021 ! occipital lobe intersection_of: part_of UBERON:0002812 ! left cerebral hemisphere relationship: adjacent_to UBERON:0002921 ! longitudinal fissure relationship: spatially_disjoint_from UBERON:0002807 ! right occipital lobe xref: SCTID:314150007 ! Entire left occipital lobe def: "An occipital lobe that is part of a left cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002807 name: right occipital lobe xref: FMA:72975 ! Right occipital lobe xref: NIF_GrossAnatomy:birnlex_1783 ! Right occipital lobe xref: OpenCyc:Mx8Ngh4rvgHsHZwpEbGdrcN5Y29ycB4rv9OFy5wpEbGdrcN5Y29ycA ! right occipital lobe intersection_of: UBERON:0002021 ! occipital lobe intersection_of: part_of UBERON:0002813 ! right cerebral hemisphere relationship: adjacent_to UBERON:0002921 ! longitudinal fissure xref: SCTID:314149007 ! Entire right occipital lobe def: "An occipital lobe that is part of a right cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002808 name: left temporal lobe xref: FMA:72972 ! Left temporal lobe xref: NIF_GrossAnatomy:birnlex_1784 ! Left temporal lobe xref: OpenCyc:Mx8Ngh4rvgIFoJwpEbGdrcN5Y29ycB4rwQLi-ZwpEbGdrcN5Y29ycA ! left temporal lobes intersection_of: UBERON:0001871 ! temporal lobe intersection_of: part_of UBERON:0002812 ! left cerebral hemisphere xref: SCTID:314158000 ! Entire left temporal lobe def: "A temporal lobe that is part of a left cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002809 name: right temporal lobe xref: FMA:72971 ! Right temporal lobe xref: NIF_GrossAnatomy:birnlex_1785 ! Right temporal lobe xref: OpenCyc:Mx8Ngh4rvgHsHZwpEbGdrcN5Y29ycB4rwQLi-ZwpEbGdrcN5Y29ycA ! right temporal lobe intersection_of: UBERON:0001871 ! temporal lobe intersection_of: part_of UBERON:0002813 ! right cerebral hemisphere xref: SCTID:314157005 ! Entire right temporal lobe def: "A temporal lobe that is part of a right cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002810 name: right frontal lobe xref: FMA:72969 ! Right frontal lobe xref: NIF_GrossAnatomy:birnlex_1786 ! Right frontal lobe intersection_of: UBERON:0001870 ! frontal lobe intersection_of: part_of UBERON:0002813 ! right cerebral hemisphere relationship: adjacent_to UBERON:0002921 ! longitudinal fissure xref: SCTID:314141005 ! Entire right frontal lobe def: "A frontal cortex that is part of a right cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002811 name: left frontal lobe xref: FMA:72970 ! Left frontal lobe xref: NIF_GrossAnatomy:birnlex_1787 ! Left frontal lobe intersection_of: UBERON:0001870 ! frontal lobe intersection_of: part_of UBERON:0002812 ! left cerebral hemisphere relationship: adjacent_to UBERON:0002921 ! longitudinal fissure relationship: spatially_disjoint_from UBERON:0002810 ! right frontal lobe xref: SCTID:314142003 ! Entire left frontal lobe def: "A frontal cortex that is part of a left cerebral hemisphere." [OBOL:automatic] [Term] id: UBERON:0002814 name: posterior superior fissure synonym: "post-clival fissure" EXACT [FMA:83733] synonym: "postclival fissure" EXACT [FMA:83733] synonym: "postlunate fissure" EXACT [FMA:83733] synonym: "posterior superior fissure of cerebellum" EXACT [FMA:83733] xref: FMA:83733 ! Posterior superior fissure of cerebellum xref: NIF_GrossAnatomy:birnlex_20081254 xref: NIF_GrossAnatomy:nlx_anat_20081254 ! Posterior superior fIssure is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002037 ! cerebellum synonym: "fissura post clivalis" EXACT LATIN [FMA:TA, FMA:83733] xref: SCTID:314170001 ! Superior posterior cerebellar fissure [Term] id: UBERON:0002815 name: horizontal fissure def: "The largest and deepest fissure in the cerebellum is named the horizontal sulcus (or horizontal fissure). It commences in front of the pons, and passes horizontally around the free margin of the hemisphere to the middle line behind, and divides the cerebellum into an upper and a lower portion. [WP,unvetted]." [Wikipedia:Horizontal_fissure_of_cerebellum] synonym: "horizontal fissure of cerebellum" EXACT [] synonym: "horizontal sulcus" EXACT [] synonym: "horizontal fissure of right lung(line)" EXACT [FMA:14697] synonym: "great horizontal fissure" EXACT [FMA:75135] synonym: "intercrural fissure of cerebellum" EXACT [FMA:75135] xref: NIF_GrossAnatomy:birnlex_20081255 xref: FMA:14697 ! Horizontal fissure xref: FMA:75135 ! Horizontal fissure of cerebellum xref: NIF_GrossAnatomy:nlx_anat_20081255 ! Horizontal fissure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Gray702.png/200px-Gray702.png is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002037 ! cerebellum synonym: "fissura intercruralis cerebelli" EXACT LATIN [FMA:TA, FMA:75135] xref: SCTID:314173004 ! Horizontal cerebellar fissure synonym: "fissura horizontalis" RELATED LATIN [Wikipedia:Horizontal_fissure_of_cerebellum] xref: http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray702.png [Term] id: UBERON:0002816 name: prepyramidal fissure synonym: "prebiventral fissure of cerebellum" EXACT [FMA:75138] synonym: "prepyramidal sulcus" EXACT [FMA:75138] synonym: "prepyramidal fissure of cerebellum" EXACT [FMA:75138] xref: FMA:75138 ! Prepyramidal fissure of cerebellum xref: NIF_GrossAnatomy:birnlex_20081257 xref: NIF_GrossAnatomy:nlx_anat_20081257 ! Prepyramidal fissure is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002037 ! cerebellum synonym: "fissura prebiventralis cerebelli" EXACT LATIN [FMA:TA, FMA:75138] xref: SCTID:314171002 ! Entire prepyramidal fissure [Term] id: UBERON:0002817 name: secondary fissure synonym: "post-pyramidal fissure of cerebellum" EXACT [FMA:84043] synonym: "postpyramidal fissure" EXACT [FMA:84043] synonym: "secondary fissure" EXACT [FMA:84043] synonym: "secondary fissure of cerebellum" EXACT [FMA:84043] xref: FMA:84043 ! Secondary fissure of cerebellum xref: NIF_GrossAnatomy:birnlex_20081258 xref: NIF_GrossAnatomy:nlx_anat_20081258 ! Secondary fissure is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002037 ! cerebellum synonym: "fissura postpyramidalis cerebelli" EXACT LATIN [FMA:TA, FMA:84043] xref: SCTID:314169002 ! Secondary cerebellar fissure [Term] id: UBERON:0002818 name: posterolateral fissure synonym: "dorsolateral fissure of cerebellum" EXACT [FMA:83730] synonym: "prenodular fissure" EXACT [FMA:83730] synonym: "prenodular sulcus" EXACT [FMA:83730] synonym: "uvulonodular fissure" EXACT [FMA:83730] synonym: "posterolateral fissure of cerebellum" EXACT [FMA:83730] xref: FMA:83730 ! Posterolateral fissure of cerebellum xref: NIF_GrossAnatomy:birnlex_20081259 xref: NIF_GrossAnatomy:nlx_anat_20081259 ! Posterolateral fissure is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002037 ! cerebellum xref: SCTID:314172009 ! Posterolateral cerebellar fissure [Term] id: UBERON:0002819 name: apex of cochlea def: "The cupula is a structure in the vestibular system, sensing proprioception. The cupula is located within the ampullae of each of the three semicircular canals. As fluid rushes by the cupula, hair cells within it sense rotational acceleration, and transmit the corresponding signal to the brain through the vestibulocochlear nerve (CN VIII) In their natural orientation within the head, the cupulae are located on the medial aspect of the semicircular canals. In this orientation, the kinocilia rest on the posterior aspect of the cupula. [WP,unvetted]." [Wikipedia:Apex_of_cochlea] subset: uberon_slim synonym: "cochlea apex" EXACT [FMA:75641] synonym: "cupula of cochlea" EXACT [FMA:75641] xref: FMA:75641 ! Apex of cochlea xref: NIF_GrossAnatomy:birnlex_2523 ! Apex of cochlea is_a: UBERON:0000477 ! anatomical cluster relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception [Term] id: UBERON:0002820 name: zona arcuata of basilar membrane of cochlea alt_id: UBERON:0002821 xref: FMA:75709 ! Zona arcuata of basilar membrane of cochlea xref: NIF_GrossAnatomy:birnlex_2528 ! Zona arcuata of basilar membrane of cochlea is_a: UBERON:0005764 ! acellular membrane [Term] id: UBERON:0002822 name: macula lutea proper xref: FMA:58671 ! Macula lutea proper xref: NIF_GrossAnatomy:birnlex_2542 ! Macula lutea proper is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000053 ! macula lutea [Term] id: UBERON:0002823 name: clivus of fovea centralis comment: NIF differs from FMA synonym: "fovea centralis clivus" EXACT [FMA:58674] synonym: "clivus of macula lutea" EXACT [NIF_GrossAnatomy:birnlex_2544] xref: FMA:58674 ! Clivus of fovea centralis xref: NIF_GrossAnatomy:birnlex_2544 ! Clivus of fovea centralis is_a: UBERON:0000466 ! immaterial anatomical entity relationship: part_of UBERON:0001786 ! fovea centralis [Term] id: UBERON:0002825 name: superior part of vestibular ganglion synonym: "vestibular ganglion superior part" EXACT [MA:0002778] synonym: "pars superior vestibularis" RELATED [MA:0002778] xref: FMA:77531 ! Superior part of vestibular ganglion xref: NIF_GrossAnatomy:birnlex_2551 ! Superior part of vestibular ganglion xref: MA:0002778 ! vestibular ganglion superior part is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002824 ! vestibular ganglion [Term] id: UBERON:0002826 name: inferior part of vestibular ganglion synonym: "vestibular ganglion inferior part" EXACT [MA:0002779] xref: FMA:77532 ! Inferior part of vestibular ganglion xref: NIF_GrossAnatomy:birnlex_2552 ! Inferior part of vestibular ganglion xref: MA:0002779 ! vestibular ganglion inferior part is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002824 ! vestibular ganglion [Term] id: UBERON:0002828 name: ventral cochlear nucleus def: "The ventral cochlear nucleus (or anterior, or accessory), placed between the two divisions of the cochlear nerve, is on the ventral aspect of the inferior peduncle. Composed of several regions of distinct cell types, this nucleus serves primarily as a relay station for ascending auditory information. Bushy cells in the anterior ventral cochlear nucleus (AVCN), which receive end bulbs of held from auditory nerve fibers, project to the superior olivary complex through the trapezoid body and intermediate acoustic stria. Other cell types project to the lateral lemniscus and the inferior colliculus directly. [WP,unvetted]." [Wikipedia:Ventral_cochlear_nucleus] subset: uberon_slim synonym: "ventral cochlear nucleus" EXACT [FMA:54621] synonym: "anterior cochlear nucleus" EXACT [FMA:54621] synonym: "c1281209" EXACT [NIF_GrossAnatomy:birnlex_2567] xref: FMA:54621 ! Anterior cochlear nucleus xref: NIF_GrossAnatomy:birnlex_2567 ! Ventral cochlear nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Gray760.png/200px-Gray760.png xref: ABA:VCO ! Ventral cochlear nucleus xref: BM:CV ! ventral cochlear nucleus is_a: UBERON:0001720 ! cochlear nucleus xref: SCTID:280178008 ! Entire ventral cochlear nucleus [Term] id: UBERON:0002829 name: dorsal cochlear nucleus def: "The dorsal cochlear nucleus (DCN, also known as the 'tuberculum acousticum'), is a cortex-like structure on the dorso-lateral surface of the brainstem. Along with the ventral cochlear nucleus, it forms the cochlear nucleus, where all auditory nerve fibers from the cochlea form their first synapses. [WP,unvetted]." [Wikipedia:Dorsal_cochlear_nucleus] subset: uberon_slim synonym: "tuberculum acousticum" EXACT [] synonym: "dorsal cochlear nucleus" EXACT [FMA:54624] synonym: "dorsal division of cochlear nucleus" EXACT [FMA:54624] synonym: "posterior cochlear nucleus" EXACT [FMA:54624] xref: FMA:54624 ! Posterior cochlear nucleus xref: NIF_GrossAnatomy:birnlex_2569 ! Dorsal cochlear nucleus xref: ncithesaurus:Dorsal_Cochlear_Nucleus ! Dorsal Cochlear Nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Gray760.png/200px-Gray760.png xref: ABA:DCO ! Dorsal cochlear nucleus xref: BM:Me-CD ! dorsal cochlear nucleus is_a: UBERON:0001720 ! cochlear nucleus xref: SCTID:280179000 ! Entire dorsal cochlear nucleus synonym: "nucleus cochlearis posterior" RELATED LATIN [Wikipedia:Dorsal_cochlear_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/b/bb/Gray760.png xref: UMLS:C0175499 [Term] id: UBERON:0002830 name: anteroventral cochlear nucleus synonym: "anteroventral auditory nucleus" EXACT [FMA:72571] synonym: "anterior part of anterior cochlear nucleus" EXACT [NIF_GrossAnatomy:birnlex_2572] synonym: "nucleus magnocellularis" EXACT [NIF_GrossAnatomy:birnlex_2572] xref: FMA:72571 ! Anteroventral cochlear nucleus xref: NIF_GrossAnatomy:birnlex_2572 ! Anteroventral cochlear nucleus is_a: UBERON:0001720 ! cochlear nucleus [Term] id: UBERON:0002831 name: posteroventral cochlear nucleus synonym: "posterior part of anterior cochlear nucleus" EXACT [NIF_GrossAnatomy:birnlex_2573] xref: FMA:72572 ! Posteroventral cochlear nucleus xref: NIF_GrossAnatomy:birnlex_2573 ! Posteroventral cochlear nucleus is_a: UBERON:0001720 ! cochlear nucleus [Term] id: UBERON:0007633 ! nucleus of trapezoid body name: nucleus of trapezoid body comment: consider splitting into nucleus and complex xref: ABA:NTB ! Nucleus of the trapezoid body xref: MA:0001018 ! nucleus of trapezoid body xref: BM:NTB ! nucleus of trapezoid body xref: FMA:84023 ! set of nuclei of trapezoid body is_a: UBERON:0006331 {source="MA"} ! brainstem nucleus relationship: part_of UBERON:0000988 {source="MA"} ! pons relationship: spatially_disjoint_from UBERON:0002162 {source="ABA"} ! area postrema relationship: spatially_disjoint_from UBERON:0002610 {source="ABA"} ! cochlear nuclear complex relationship: spatially_disjoint_from UBERON:0002864 {source="ABA"} ! accessory cuneate nucleus relationship: spatially_disjoint_from UBERON:0002126 {source="ABA"} ! solitary tract nuclear complex relationship: spatially_disjoint_from UBERON:0002866 {source="ABA"} ! caudal part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002873 {source="ABA"} ! interpolar part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002591 {source="ABA"} ! oral part of spinal trigeminal nucleus xref: SCTID:362405000 ! Entire trapezoid body nucleus xref: NIF_GrossAnatomy:birnlex_745 ! Trapezoid nuclear complex synonym: "set of nuclei of trapezoid body" RELATED [FMA:84023] synonym: "nuclei of trapezoid body" RELATED [FMA:84023] [Term] id: UBERON:0002832 name: ventral nucleus of trapezoid body synonym: "anterior nucleus of trapezoid body" EXACT [FMA:72477] xref: FMA:72477 ! Ventral nucleus of trapezoid body xref: NIF_GrossAnatomy:birnlex_2576 ! Ventral nucleus of trapezoid body is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0007633 ! nucleus of trapezoid body relationship: part_of UBERON:0002128 ! superior olivary complex synonym: "nucleus anterior corporis trapezoidei" EXACT LATIN [FMA:TA, FMA:72477] xref: SCTID:369020000 ! Entire ventral nucleus of trapezoid body [Term] id: UBERON:0002833 name: medial nucleus of trapezoid body xref: FMA:75732 ! Medial nucleus of trapezoid body xref: NIF_GrossAnatomy:birnlex_2595 ! Medial nucleus of trapezoid body is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0007633 ! nucleus of trapezoid body [Term] id: UBERON:0009053 name: dorsal nucleus of trapezoid body synonym: "dorsal nucleus of trapezoid body" EXACT [NIF_GrossAnatomy:birnlex_2575] xref: NIF_GrossAnatomy:birnlex_2575 ! Dorsal nucleus of trapezoid body xref: SCTID:369021001 ! Entire dorsal nucleus of trapezoid body is_a: UBERON:0007633 ! nucleus of trapezoid body [Term] id: UBERON:0002834 name: cervical dorsal root ganglion synonym: "cervical dorsal root ganglion" EXACT [FMA:6005] synonym: "cervical spinal ganglion" EXACT [FMA:6005] xref: FMA:6005 ! Cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2599 ! Cervical dorsal root ganglion is_a: UBERON:0000044 ! dorsal root ganglion xref: SCTID:278325008 ! Cervical spinal ganglion [Term] id: UBERON:0002835 name: thoracic dorsal root ganglion def: "A dorsal root ganglion that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "thoracic dorsal root ganglion" EXACT [FMA:6006] synonym: "dorsal root ganglion of thorax" EXACT [OBOL:automatic] synonym: "ganglion spinalis of thorax" EXACT [OBOL:automatic] synonym: "thorax dorsal root ganglion" EXACT [OBOL:automatic] synonym: "thorax ganglion spinalis" EXACT [OBOL:automatic] synonym: "ganglion of dorsal root of thorax" EXACT [OBOL:automatic] synonym: "thorax ganglion of dorsal root" EXACT [OBOL:automatic] synonym: "thoracic spinal ganglion" EXACT [FMA:6006] xref: FMA:6006 ! Thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2600 ! Thoracic dorsal root ganglion is_a: UBERON:0000044 ! dorsal root ganglion is_a: UBERON:0000961 ! thoracic ganglion intersection_of: UBERON:0000044 ! dorsal root ganglion intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk xref: SCTID:278326009 ! Thoracic spinal ganglion [Term] id: UBERON:0002836 name: lumbar dorsal root ganglion def: "the group of nerve cell bodies located on the dorsal spinal roots within the vertebral column at the level of the lumbar vertebrae." [MP:0006404] synonym: "lumbar dorsal root ganglion" EXACT [FMA:6007] synonym: "lumbar spinal ganglion" EXACT [FMA:6007] xref: FMA:6007 ! Lumbar spinal ganglion xref: NIF_GrossAnatomy:birnlex_2601 ! Lumbar dorsal root ganglion is_a: UBERON:0000044 ! dorsal root ganglion xref: SCTID:278327000 ! Lumbar spinal ganglion [Term] id: UBERON:0002837 name: sacral dorsal root ganglion synonym: "sacral dorsal root ganglion" EXACT [FMA:6008] synonym: "sacral spinal ganglion" EXACT [FMA:6008] xref: FMA:6008 ! Sacral spinal ganglion xref: NIF_GrossAnatomy:birnlex_2602 ! Sacral dorsal root ganglion is_a: UBERON:0000044 ! dorsal root ganglion xref: SCTID:278328005 ! Sacral spinal ganglion [Term] id: UBERON:0002838 name: first cervical dorsal root ganglion subset: defined_by_ordinal_series synonym: "first cervical dorsal root ganglion" EXACT [FMA:6010] synonym: "first cervical spinal ganglion" EXACT [FMA:6010] xref: FMA:6010 ! First cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2603 ! First cervical dorsal root ganglion xref: EMAPA:25144 ! C1 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002834 ! cervical dorsal root ganglion [Term] id: UBERON:0002839 name: second cervical dorsal root ganglion subset: defined_by_ordinal_series synonym: "second cervical dorsal root ganglion" EXACT [FMA:6315] synonym: "second cervical spinal ganglion" EXACT [FMA:6315] xref: FMA:6315 ! Second cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2604 ! Second cervical dorsal root ganglion xref: EMAPA:25155 ! C2 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002834 ! cervical dorsal root ganglion [Term] id: UBERON:0002840 name: third cervical dorsal root ganglion subset: defined_by_ordinal_series synonym: "third cervical dorsal root ganglion" EXACT [FMA:6316] synonym: "third cervical spinal ganglion" EXACT [FMA:6316] xref: FMA:6316 ! Third cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2605 ! Third cervical dorsal root ganglion xref: EMAPA:25156 ! C3 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002834 ! cervical dorsal root ganglion [Term] id: UBERON:0002841 name: fourth cervical dorsal root ganglion subset: defined_by_ordinal_series synonym: "fourth cervical dorsal root ganglion" EXACT [FMA:6317] synonym: "fourth cervical spinal ganglion" EXACT [FMA:6317] xref: FMA:6317 ! Fourth cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2606 ! Fourth cervical dorsal root ganglion xref: EMAPA:25157 ! C4 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002834 ! cervical dorsal root ganglion [Term] id: UBERON:0002842 name: fifth cervical dorsal root ganglion subset: defined_by_ordinal_series synonym: "fifth cervical dorsal root ganglion" EXACT [FMA:6318] synonym: "fifth cervical spinal ganglion" EXACT [FMA:6318] xref: FMA:6318 ! Fifth cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2607 ! Fifth cervical dorsal root ganglion xref: EMAPA:25158 ! C5 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002834 ! cervical dorsal root ganglion [Term] id: UBERON:0007711 name: sixth cervical dorsal root ganglion synonym: "sixth cervical dorsal root ganglion" EXACT [NIF_GrossAnatomy:birnlex_2608] synonym: "sixth cervical spinal ganglion" EXACT [FMA:6319] synonym: "sixth cervical dorsal root ganglia" EXACT [FMA:6319] xref: NIF_GrossAnatomy:birnlex_2608 ! Sixth cervical dorsal root ganglion xref: FMA:6319 ! sixth cervical spinal ganglion xref: EMAPA:25159 ! C6 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002834 {source="NIF_GrossAnatomy"} ! cervical dorsal root ganglion [Term] id: UBERON:0002843 name: seventh cervical dorsal root ganglion subset: defined_by_ordinal_series synonym: "seventh cervical dorsal root ganglion" EXACT [FMA:6360] synonym: "seventh cervical spinal ganglion" EXACT [FMA:6360] xref: FMA:6360 ! Seventh cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2609 ! Seventh cervical dorsal root ganglion xref: EMAPA:25160 ! C7 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002834 ! cervical dorsal root ganglion [Term] id: UBERON:0002844 name: eighth cervical dorsal root ganglion subset: defined_by_ordinal_series synonym: "eighth cervical dorsal root ganglion" EXACT [FMA:6361] synonym: "eighth cervical spinal ganglion" EXACT [FMA:6361] xref: FMA:6361 ! Eighth cervical spinal ganglion xref: NIF_GrossAnatomy:birnlex_2610 ! Eighth cervical dorsal root ganglion is_a: UBERON:0002834 ! cervical dorsal root ganglion [Term] id: UBERON:0002845 name: first thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "first thoracic dorsal root ganglion" EXACT [FMA:6321] synonym: "first thoracic spinal ganglion" EXACT [FMA:6321] xref: FMA:6321 ! First thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2611 ! First thoracic dorsal root ganglion xref: EMAPA:25174 ! T1 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002846 name: second thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "second thoracic dorsal root ganglion" EXACT [FMA:6322] synonym: "second thoracic spinal ganglion" EXACT [FMA:6322] xref: FMA:6322 ! Second thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2612 ! Second thoracic dorsal root ganglion xref: EMAPA:25175 ! T2 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002847 name: third thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "third thoracic dorsal root ganglion" EXACT [FMA:6323] synonym: "third thoracic spinal ganglion" EXACT [FMA:6323] xref: FMA:6323 ! Third thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2613 ! Third thoracic dorsal root ganglion xref: EMAPA:25176 ! T3 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0007712 name: fourth thoracic spinal ganglion subset: defined_by_ordinal_series synonym: "fourth thoracic dorsal root ganglion" EXACT [FMA:6324] synonym: "forth thoracic dorsal root ganglion" EXACT [NIF_GrossAnatomy:birnlex_2614] synonym: "fourth thoracic dorsal root ganglion" EXACT [UBERON:cjm] xref: FMA:6324 ! fourth thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2614 ! Forth thoracic dorsal root ganglion xref: EMAPA:25177 ! T4 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 {source="FMA"} ! thoracic dorsal root ganglion [Term] id: UBERON:0002848 name: fifth thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "fifth thoracic dorsal root ganglion" EXACT [FMA:6325] synonym: "fifth thoracic spinal ganglion" EXACT [FMA:6325] xref: FMA:6325 ! Fifth thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2615 ! Fifth thoracic dorsal root ganglion xref: EMAPA:25179 ! T5 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002849 name: sixth thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "sixth thoracic dorsal root ganglion" EXACT [FMA:6326] synonym: "sixth thoracic spinal ganglion" EXACT [FMA:6326] xref: FMA:6326 ! Sixth thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2616 ! Sixth thoracic dorsal root ganglion xref: EMAPA:25178 ! T6 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002850 name: seventh thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "seventh thoracic dorsal root ganglion" EXACT [FMA:6327] synonym: "seventh thoracic spinal ganglion" EXACT [FMA:6327] xref: FMA:6327 ! Seventh thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2617 ! Seventh thoracic dorsal root ganglion xref: EMAPA:25180 ! T7 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002851 name: eighth thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "eighth thoracic dorsal root ganglion" EXACT [FMA:6328] synonym: "eighth thoracic spinal ganglion" EXACT [FMA:6328] xref: FMA:6328 ! Eighth thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2618 ! Eighth thoracic dorsal root ganglion xref: EMAPA:25181 ! T8 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002852 name: ninth thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "ninth thoracic dorsal root ganglion" EXACT [FMA:6329] synonym: "ninth thoracic spinal ganglion" EXACT [FMA:6329] xref: FMA:6329 ! Ninth thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2619 ! Ninth thoracic dorsal root ganglion xref: EMAPA:25182 ! T9 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002853 name: tenth thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "tenth thoracic dorsal root ganglion" EXACT [FMA:6330] synonym: "tenth thoracic spinal ganglion" EXACT [FMA:6330] xref: FMA:6330 ! Tenth thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2620 ! Tenth thoracic dorsal root ganglion xref: EMAPA:25183 ! T10 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002854 name: eleventh thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "eleventh thoracic dorsal root ganglion" EXACT [FMA:6331] synonym: "eleventh thoracic spinal ganglion" EXACT [FMA:6331] xref: FMA:6331 ! Eleventh thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2621 ! Eleventh thoracic dorsal root ganglion xref: EMAPA:25184 ! T11 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002855 name: twelfth thoracic dorsal root ganglion subset: defined_by_ordinal_series synonym: "twelfth thoracic dorsal root ganglion" EXACT [FMA:6332] synonym: "twelfth thoracic spinal ganglion" EXACT [FMA:6332] xref: FMA:6332 ! Twelfth thoracic spinal ganglion xref: NIF_GrossAnatomy:birnlex_2622 ! Twelfth thoracic dorsal root ganglion xref: EMAPA:25185 ! T12 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002835 ! thoracic dorsal root ganglion [Term] id: UBERON:0002857 name: first lumbar dorsal root ganglion subset: defined_by_ordinal_series synonym: "first lumbar dorsal root ganglion" EXACT [FMA:6335] synonym: "first lumbar spinal ganglion" EXACT [FMA:6335] xref: FMA:6335 ! First lumbar spinal ganglion xref: NIF_GrossAnatomy:birnlex_2624 ! First lumbar dorsal root ganglion xref: EMAPA:25164 ! L1 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002836 ! lumbar dorsal root ganglion [Term] id: UBERON:0002856 name: second lumbar dorsal root ganglion subset: defined_by_ordinal_series synonym: "second lumbar dorsal root ganglion" EXACT [FMA:6336] synonym: "second lumbar spinal ganglion" EXACT [FMA:6336] xref: FMA:6336 ! Second lumbar spinal ganglion xref: NIF_GrossAnatomy:birnlex_2623 ! Second lumbar dorsal root ganglion xref: EMAPA:25165 ! L2 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002836 ! lumbar dorsal root ganglion [Term] id: UBERON:0002858 name: third lumbar dorsal root ganglion subset: defined_by_ordinal_series synonym: "third lumbar dorsal root ganglion" EXACT [FMA:6337] synonym: "third lumbar spinal ganglion" EXACT [FMA:6337] xref: EMAPA:25166 ! L3 of dorsal root ganglion of ganglion of spinal xref: FMA:6337 ! Third lumbar spinal ganglion xref: NIF_GrossAnatomy:birnlex_2625 ! Third lumbar dorsal root ganglion is_a: UBERON:0002836 ! lumbar dorsal root ganglion [Term] id: UBERON:0003943 name: fourth lumbar dorsal root ganglion def: "the group of nerve cell bodies located on the dorsal spinal roots within the vertebral column at the level of the fourth lumbar vertebra" [MP:0001019] subset: defined_by_ordinal_series synonym: "fourth lumbar spinal ganglion" EXACT [FMA:6338] synonym: "L4 dorsal root ganglion" EXACT [MP:0001019] synonym: "fourth lumbar spinal ganglion" EXACT [FMA:6338] synonym: "forth lumbar dorsal root ganglion" EXACT [NIF_GrossAnatomy:birnlex_2626] synonym: "fourth lumbar dorsal root ganglion" EXACT [UBERON:cjm] xref: EMAPA:25167 ! L4 of dorsal root ganglion of ganglion of spinal xref: FMA:6338 ! fourth lumbar spinal ganglion xref: NIF_GrossAnatomy:birnlex_2626 ! Forth lumbar dorsal root ganglion is_a: UBERON:0002836 {source="FMA"} ! lumbar dorsal root ganglion [Term] id: UBERON:0002859 name: fifth lumbar dorsal root ganglion alt_id: UBERON:0003944 def: "the group of nerve cell bodies located on the dorsal spinal roots within the vertebral column at the level of the fifth lumbar vertebra" [MP:0001022] subset: defined_by_ordinal_series synonym: "L5 dorsal root ganglion" EXACT [MP:0001022] synonym: "fifth lumbar dorsal root ganglion" EXACT [FMA:6339] synonym: "fifth lumbar spinal ganglion" EXACT [FMA:6339] xref: FMA:6339 ! Fifth lumbar spinal ganglion xref: NIF_GrossAnatomy:birnlex_2627 ! Fifth lumbar dorsal root ganglion xref: EMAPA:25168 ! L5 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002836 ! lumbar dorsal root ganglion [Term] id: UBERON:0002860 name: first sacral dorsal root ganglion subset: defined_by_ordinal_series synonym: "first sacral dorsal root ganglion" EXACT [FMA:6342] synonym: "first sacral spinal ganglion" EXACT [FMA:6342] xref: FMA:6342 ! First sacral spinal ganglion xref: NIF_GrossAnatomy:birnlex_2628 ! First sacral dorsal root ganglion xref: EMAPA:25170 ! S1 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002837 ! sacral dorsal root ganglion [Term] id: UBERON:0002861 name: second sacral dorsal root ganglion subset: defined_by_ordinal_series synonym: "second sacral dorsal root ganglion" EXACT [FMA:6343] synonym: "second sacral spinal ganglion" EXACT [FMA:6343] xref: FMA:6343 ! Second sacral spinal ganglion xref: NIF_GrossAnatomy:birnlex_2629 ! Second sacral dorsal root ganglion xref: EMAPA:25171 ! S2 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002837 ! sacral dorsal root ganglion [Term] id: UBERON:0002862 name: third sacral dorsal root ganglion subset: defined_by_ordinal_series synonym: "third sacral dorsal root ganglion" EXACT [FMA:6344] synonym: "third sacral spinal ganglion" EXACT [FMA:6344] xref: FMA:6344 ! Third sacral spinal ganglion xref: NIF_GrossAnatomy:birnlex_2630 ! Third sacral dorsal root ganglion xref: EMAPA:25172 ! S3 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002837 ! sacral dorsal root ganglion [Term] id: UBERON:0007713 name: fourth sacral spinal ganglion synonym: "fourth sacral dorsal root ganglion" EXACT [FMA:6345] synonym: "forth sacral dorsal root ganglion" EXACT [NIF_GrossAnatomy:birnlex_2631] synonym: "fourth sacral dorsal root ganglion" EXACT [UBERON:cjm] xref: FMA:6345 ! fourth sacral spinal ganglion xref: NIF_GrossAnatomy:birnlex_2631 ! Forth sacral dorsal root ganglion xref: EMAPA:25173 ! S4 of dorsal root ganglion of ganglion of spinal is_a: UBERON:0002837 {source="FMA"} ! sacral dorsal root ganglion [Term] id: UBERON:0002863 name: fifth sacral dorsal root ganglion subset: defined_by_ordinal_series synonym: "fifth sacral dorsal root ganglion" EXACT [FMA:6346] synonym: "fifth sacral spinal ganglion" EXACT [FMA:6346] xref: FMA:6346 ! Fifth sacral spinal ganglion xref: NIF_GrossAnatomy:birnlex_2632 ! Fifth sacral dorsal root ganglion is_a: UBERON:0002837 ! sacral dorsal root ganglion [Term] id: UBERON:0002864 name: accessory cuneate nucleus def: "The accessory cuneate nucleus is located lateral to the cuneate nucleus in the medulla oblongata at the level of the sensory decussation. It receives input from cervical spinal nerves and transmits that information to the cerebellum. These fibers are called cuneocerebellar (cuneate nucleus > cerebellum) fibers. In this function, the accessory cuneate nucleus is comparable to the upper extremity portion of the posterior spinocerebellar tract. [WP,unvetted]." [Wikipedia:Accessory_cuneate_nucleus] subset: uberon_slim synonym: "external cuneate nucleus" EXACT [FMA:72603] synonym: "lateral cuneate nucleus" EXACT [FMA:72603] synonym: "nucleus of corpus restiforme" EXACT [FMA:72603] xref: FMA:72603 ! Accessory cuneate nucleus xref: NIF_GrossAnatomy:birnlex_2634 ! Accessory cuneate nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/94/Gray694.png/200px-Gray694.png xref: EV:0100285 ! accessory cuneate nucleus xref: ABA:ECU ! External cuneate nucleus xref: BM:Me-CX ! external cuneate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002162 {source="ABA"} ! area postrema relationship: spatially_disjoint_from UBERON:0002610 {source="ABA"} ! cochlear nuclear complex relationship: spatially_disjoint_from UBERON:0007633 {source="ABA"} ! nucleus of trapezoid body relationship: spatially_disjoint_from UBERON:0002126 {source="ABA"} ! solitary tract nuclear complex relationship: spatially_disjoint_from UBERON:0002866 {source="ABA"} ! caudal part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002873 {source="ABA"} ! interpolar part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002591 {source="ABA"} ! oral part of spinal trigeminal nucleus xref: SCTID:15575006 ! Entire accessory cuneate nucleus synonym: "nucleus cuneatus accessorius" RELATED LATIN [Wikipedia:Accessory_cuneate_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png [Term] id: UBERON:0002865 name: arcuate nucleus of medulla def: "An arcuate nucleus of hypothalamus that is part of a medulla [Automatically generated definition]." [OBOL:automatic] synonym: "arcuate nucleus-1" EXACT [FMA:72609] synonym: "medial arcuate nucleus" EXACT [FMA:72609] synonym: "arcuate hypothalamic nucleus of medulla" EXACT [OBOL:automatic] synonym: "arcuate nucleus of hypothalamus of medulla" EXACT [OBOL:automatic] synonym: "arcuate nucleus-2 of medulla" EXACT [OBOL:automatic] synonym: "arcuate periventricular nucleus of medulla" EXACT [OBOL:automatic] synonym: "infundibular hypothalamic nucleus of medulla" EXACT [OBOL:automatic] synonym: "infundibular nucleus of medulla" EXACT [OBOL:automatic] synonym: "infundibular periventricular nucleus of medulla" EXACT [OBOL:automatic] synonym: "medulla arcuate hypothalamic nucleus" EXACT [OBOL:automatic] synonym: "medulla arcuate nucleus" EXACT [OBOL:automatic] synonym: "medulla arcuate nucleus of hypothalamus" EXACT [OBOL:automatic] synonym: "medulla arcuate nucleus-2" EXACT [OBOL:automatic] synonym: "medulla arcuate periventricular nucleus" EXACT [OBOL:automatic] synonym: "medulla infundibular hypothalamic nucleus" EXACT [OBOL:automatic] synonym: "medulla infundibular nucleus" EXACT [OBOL:automatic] synonym: "medulla infundibular periventricular nucleus" EXACT [OBOL:automatic] synonym: "nucleus arciformis pyramidalis" EXACT [NIF_GrossAnatomy:birnlex_2635] xref: FMA:72609 ! Arcuate nucleus of medulla xref: NIF_GrossAnatomy:birnlex_2635 ! Arcuate nucleus of medulla is_a: UBERON:0002020 ! gray matter of neuraxis intersection_of: UBERON:0001932 ! arcuate nucleus of hypothalamus intersection_of: part_of UBERON:0000958 ! medulla [Term] id: UBERON:0002866 name: caudal part of spinal trigeminal nucleus synonym: "caudal nucleus (kandell)" EXACT [] synonym: "spinal trigeminal nucleus, caudal part" EXACT [FMA:72606] synonym: "caudal nucleus" EXACT [NIF_GrossAnatomy:birnlex_2637] xref: FMA:72606 ! Caudal part of spinal trigeminal nucleus xref: NIF_GrossAnatomy:birnlex_2637 ! Caudal part of spinal trigeminal nucleus xref: MESH:A08.186.211.132.931.920.927 ! trigeminal caudal nucleu xref: EV:0100235 ! posterior nucleus (also: UBERON:0002706 'posterior nucleus of hypothalamus') xref: ABA:SPVC ! Spinal nucleus of the trigeminal, caudal part is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001717 ! spinal nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002162 {source="ABA"} ! area postrema relationship: spatially_disjoint_from UBERON:0002610 {source="ABA"} ! cochlear nuclear complex relationship: spatially_disjoint_from UBERON:0002864 {source="ABA"} ! accessory cuneate nucleus relationship: spatially_disjoint_from UBERON:0007633 {source="ABA"} ! nucleus of trapezoid body relationship: spatially_disjoint_from UBERON:0002126 {source="ABA"} ! solitary tract nuclear complex relationship: spatially_disjoint_from UBERON:0002873 {source="ABA"} ! interpolar part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002591 {source="ABA"} ! oral part of spinal trigeminal nucleus [Term] id: UBERON:0002868 name: commissural nucleus of vagus nerve synonym: "commissural nucleus-1" EXACT [FMA:54597] synonym: "nucleus of inferior commissure" EXACT [FMA:54597] synonym: "nucleus of inferior commisure" EXACT [NIF_GrossAnatomy:birnlex_2639] xref: FMA:54597 ! Commissural nucleus of vagus nerve xref: NIF_GrossAnatomy:birnlex_2639 ! Commissural nucleus of vagus nerve is_a: UBERON:0011775 {source="FMA"} ! vagus nerve nucleus [Term] id: UBERON:0011777 name: nucleus of spinal cord def: "Nucleus of neuraxis which is located within the spinal cord. Example: dorsal nucleus of Clarke, Intermediolateral nucleus." [FMA:77011] synonym: "spinal cord nucleus" EXACT [FMA:77011] intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0002240 ! spinal cord xref: FMA:77011 ! nucleus of spinal cord [Term] id: UBERON:0011776 name: spinal cord dorsal commissural nucleus comment: Editors note: check this one synonym: "commissural nucleus of spinal cord" RELATED [FMA:73900] is_a: UBERON:0011777 {source="FMA"} ! nucleus of spinal cord xref: MA:0001128 ! spinal cord dorsal commissural nucleus xref: FMA:73900 ! commissural nucleus of spinal cord [Term] id: UBERON:0002869 name: diffuse reticular nucleus synonym: "nucleus of kolliker-fuse" EXACT [] synonym: "kolloker-fuse nucleus" EXACT [NIF_GrossAnatomy:birnlex_2641] xref: FMA:72598 ! Diffuse reticular nucleus xref: NIF_GrossAnatomy:birnlex_2641 ! Diffuse reticular nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002871 name: hypoglossal nucleus def: "The hypoglossal nucleus is a cranial nerve nucleus, and it extends the length of the medulla, and being a motor nucleus, is close to the midline. In the open medulla, it is visible as what is known as the hypoglossal trigone, a raised area (medial to the vagal trigone) protruding slightly into the fourth ventricle. In the closed medulla, the gracile and cuneate nuclei lie posteriorly, which means the nucleus is not as close to the back of the medulla as in the open medulla. It is, however, still close to the midline. [WP,unvetted]." [Wikipedia:Hypoglossal_nucleus] subset: uberon_slim synonym: "hypoglossal nucleus" EXACT [FMA:54505] synonym: "nucleus of hypoglossal nerve" EXACT [FMA:54505] synonym: "twelfth cranial nerve nucleus" EXACT [FMA:54505] synonym: "hypoglossal XII nucleus" EXACT [MA:0001039] synonym: "hypoglossal nerve nucleus" EXACT [FMA:54505] xref: FMA:54505 ! Hypoglossal nerve nucleus xref: NIF_GrossAnatomy:birnlex_2644 ! Hypoglossal nucleus xref: VHOG:0001358 ! hypoglossal XII nucleus xref: MA:0001039 ! hypoglossal XII nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/94/Gray694.png/200px-Gray694.png xref: EV:0100286 ! nucleus of the hypoglossal nerve xref: ABA:XII ! Hypoglossal nucleus xref: BM:XII ! hypoglossal nucleus is_a: UBERON:0000126 ! cranial nerve nucleus relationship: part_of UBERON:0001896 ! medulla oblongata relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex synonym: "nucleus nervi hypoglossi" EXACT LATIN [FMA:TA, FMA:54505] xref: ncithesaurus:Hypoglossal_Nucleus ! Nucleus of the Hypoglossal Nerve xref: ncithesaurus:Nucleus_of_the_Hypoglossal_Nerve ! Nucleus of the Hypoglossal Nerve xref: SCTID:47361005 ! Hypoglossal nerve nucleus xref: EHDAA2:0004635 ! hypoglossal XII nucleus synonym: "nucleus nervi hypoglossi" RELATED LATIN [Wikipedia:Hypoglossal_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png xref: UMLS:C0228802 [Term] id: UBERON:0004133 ! salivatory nucleus name: salivatory nucleus def: "." [GO:0021751] synonym: "salivary nucleus" EXACT [GO:0021751] is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0000988 ! pons [Term] id: UBERON:0010124 name: future inferior salivatory nucleus comment: TODO - devfrom intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: develops_into UBERON:0002872 ! inferior salivatory nucleus xref: EHDAA2:0004643 ! future inferior salivatory nucleus def: "A gray matter of neuraxis that develops_into a inferior salivatory nucleus." [OBOL:automatic] [Term] id: UBERON:0002872 name: inferior salivatory nucleus def: "In the brain, the inferior salivatory nucleus is a cluster of neurons controlling the parasympathetic input to the parotid gland. It is one of the components of the glossopharyngeal nerve. [WP,unvetted]." [Wikipedia:Inferior_salivatory_nucleus] subset: uberon_slim synonym: "inferior salivary nucleus" EXACT [GO:0021752] synonym: "inferior salivatary nucleus" EXACT [] xref: FMA:72601 ! Inferior salivatory nucleus xref: NIF_GrossAnatomy:birnlex_2645 ! Inferior salivatory nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Gray843.png/200px-Gray843.png xref: ABA:ISN ! Inferior salivatory nucleus is_a: UBERON:0004133 ! salivatory nucleus relationship: continuous_with UBERON:0001649 ! glossopharyngeal nerve relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002877 {source="ABA"} ! parasolitary nucleus relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus xref: EHDAA2:0004641 ! inferior salivatory nucleus relationship: immediate_transformation_of UBERON:0010124 {evidence="definitional"} ! future inferior salivatory nucleus synonym: "nucleus salivatorius inferior" RELATED LATIN [Wikipedia:Inferior_salivatory_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/a/a0/Gray843.png [Term] id: UBERON:0002873 name: interpolar part of spinal trigeminal nucleus xref: FMA:235324 ! Interpolar part of spinal trigeminal nucleus xref: NIF_GrossAnatomy:birnlex_2646 ! Interpolar part of spinal trigeminal nucleus xref: ABA:SPVI ! Spinal nucleus of the trigeminal, interpolar part is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001717 ! spinal nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002162 {source="ABA"} ! area postrema relationship: spatially_disjoint_from UBERON:0002610 {source="ABA"} ! cochlear nuclear complex relationship: spatially_disjoint_from UBERON:0002864 {source="ABA"} ! accessory cuneate nucleus relationship: spatially_disjoint_from UBERON:0007633 {source="ABA"} ! nucleus of trapezoid body relationship: spatially_disjoint_from UBERON:0002126 {source="ABA"} ! solitary tract nuclear complex relationship: spatially_disjoint_from UBERON:0002866 {source="ABA"} ! caudal part of spinal trigeminal nucleus relationship: spatially_disjoint_from UBERON:0002591 {source="ABA"} ! oral part of spinal trigeminal nucleus [Term] id: UBERON:0002874 name: lateral pericuneate nucleus xref: FMA:72604 ! Lateral pericuneate nucleus xref: NIF_GrossAnatomy:birnlex_2647 ! Lateral pericuneate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002875 name: medial pericuneate nucleus xref: FMA:72605 ! Medial pericuneate nucleus xref: NIF_GrossAnatomy:birnlex_2648 ! Medial pericuneate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002877 name: parasolitary nucleus synonym: "nucleus fasciculus solitarius" EXACT [NIF_GrossAnatomy:birnlex_2653] synonym: "nucleus juxtasolitarius" EXACT [NIF_GrossAnatomy:birnlex_2653] xref: FMA:77091 ! Parasolitary nucleus xref: NIF_GrossAnatomy:birnlex_2653 ! Parasolitary nucleus xref: ABA:PAS ! Parasolitary nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0001719 {source="ABA"} ! nucleus ambiguus relationship: spatially_disjoint_from UBERON:0002870 {source="ABA"} ! dorsal motor nucleus of vagus nerve relationship: spatially_disjoint_from UBERON:0002155 {source="ABA"} ! gigantocellular nucleus relationship: spatially_disjoint_from UBERON:0002127 {source="ABA"} ! inferior olivary complex relationship: spatially_disjoint_from UBERON:0002872 {source="ABA"} ! inferior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002154 {source="ABA"} ! lateral reticular nucleus relationship: spatially_disjoint_from UBERON:0002559 {source="ABA"} ! medullary reticular formation relationship: spatially_disjoint_from UBERON:0002673 {source="ABA"} ! vestibular nuclear complex relationship: spatially_disjoint_from UBERON:0002871 {source="ABA"} ! hypoglossal nucleus [Term] id: UBERON:0002876 name: nucleus intercalatus alt_id: UBERON:0002878 comment: two NIF classes with the same name synonym: "intercalated nucleus of medulla" EXACT [FMA:72597] synonym: "nucleus intercalatus of medulla" EXACT [FMA:72597] synonym: "nucleus of staderini" EXACT [] synonym: "nucleus staderini" EXACT [NIF_GrossAnatomy:birnlex_2651] synonym: "nucleus staderini" EXACT [NIF_GrossAnatomy:birnlex_2654] xref: FMA:72597 ! Nucleus intercalatus xref: NIF_GrossAnatomy:birnlex_2651 ! Nucleus intercalatus xref: NIF_GrossAnatomy:birnlex_2654 ! Nucleus intercalatus xref: EV:0100291 ! nucleus intercalatus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain xref: SCTID:369077004 ! Entire nucleus intercalatus [Term] id: UBERON:0002879 name: peritrigeminal nucleus xref: FMA:72600 ! Peritrigeminal nucleus xref: NIF_GrossAnatomy:birnlex_2655 ! Peritrigeminal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002880 name: pontobulbar nucleus synonym: "nucleus of circumolivary bundle" EXACT [FMA:72608] synonym: "pontobulbar body" EXACT [FMA:72608] xref: FMA:72608 ! Pontobulbar nucleus xref: NIF_GrossAnatomy:birnlex_2656 ! Pontobulbar nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002882 name: supraspinal nucleus xref: FMA:74507 ! Supraspinal nucleus xref: NIF_GrossAnatomy:birnlex_2658 ! Supraspinal nucleus xref: EV:0100282 ! supraspinal nucleus xref: BM:SSp ! supraspinal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002883 name: central amygdaloid nucleus synonym: "central nucleus of amygdala" EXACT [FMA:74047] synonym: "central nucleus of amygda" EXACT [NIF_GrossAnatomy:birnlex_2682] synonym: "amygdala central nucleus" RELATED [BTO:0002686] synonym: "nucleus amygdalae centralis" RELATED [BTO:0002686] xref: FMA:74047 ! Central amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2682 ! Central amygdaloid nucleus xref: BTO:0002686 ! central amygdaloid nucleus xref: MA:0002923 ! central amygdaloid nucleus xref: EV:0100191 ! central amygdaloid nucleus xref: BM:Tel-Am-ACE ! central nucleus of amygdala is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001876 ! amygdala [Term] id: UBERON:0002884 name: intercalated amygdaloid nuclei synonym: "intercalated amygdaloid nuclei" EXACT [FMA:61868] synonym: "intercalated masses of nucleus amygdaloideus" EXACT [FMA:61868] synonym: "intercalated nuclei of amygdala" EXACT [FMA:61868] synonym: "intercalated amygdaloid nucleus" EXACT [FMA:61868] synonym: "massa intercalata" EXACT [NIF_GrossAnatomy:birnlex_2683] synonym: "massa intercalata of amygdala" EXACT [NIF_GrossAnatomy:birnlex_2683] synonym: "intercalated nucleus of the amygdala" EXACT [NIF_GrossAnatomy:birnlex_2683] xref: FMA:61868 ! Intercalated amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2683 ! Intercalated amygdaloid nuclei xref: MA:0002925 ! intercalated amygdaloid nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001876 ! amygdala [Term] id: UBERON:0002885 name: accessory basal amygdaloid nucleus synonym: "accessory basal nucleus of amygdala" EXACT [NIF_GrossAnatomy:birnlex_2686] synonym: "basal amygdaloid nucleus, medial part" EXACT [NIF_GrossAnatomy:birnlex_2686] synonym: "basomedial nucleus (de olmos)" EXACT [NIF_GrossAnatomy:birnlex_2686] xref: FMA:61867 ! Accessory basal amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2686 ! Accessory basal amygdaloid nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001876 ! amygdala [Term] id: UBERON:0002886 name: lateral amygdaloid nucleus synonym: "lateral nucleus of amygdala" EXACT [FMA:61866] synonym: "lateral principal nucleus of amygdala" EXACT [FMA:61866] synonym: "nucleus amygdalae lateralis" RELATED [BTO:0002704] xref: FMA:61866 ! Lateral amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2687 ! Lateral amygdaloid nucleus xref: BTO:0002704 ! lateral amygdaloid nucleus xref: MA:0002926 ! lateral amygdaloid nucleus xref: BM:Tel-Am-ALA ! lateral nucleus of amygdala xref: ABA:LA ! Lateral amygdalar nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001876 ! amygdala [Term] id: UBERON:0006107 name: basolateral amygdaloid nuclear complex synonym: "BL" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "Basolateral nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "amygdalar basolateral nucleus" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "amygdaloid basolateral complex" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "basolateral amygdaloid nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "basolateral nuclear group" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "pars basolateralis (Corpus amygdaloideum)" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "vicarious cortex" EXACT [NIF_GrossAnatomy:birnlex_2679] synonym: "amygdaloid basolateral complex" EXACT [FMA:84016] synonym: "basolateral nuclear group" EXACT [FMA:84016] synonym: "basolateral nuclei of amygdala" EXACT [FMA:84016] synonym: "vicarious cortex" EXACT [FMA:84016] synonym: "set of basolateral nuclei of amygdala" RELATED [FMA:84016] xref: FMA:84016 ! set of basolateral nuclei of amygdala xref: NIF_GrossAnatomy:birnlex_2679 ! Basolateral amygdaloid nuclear complex is_a: UBERON:0007245 ! nuclear complex of neuraxis relationship: part_of BERON:0001876 ! amygdala relationship: spatially_disjoint_from UBERON:0002023 {source="ABA"} ! claustrum [Term] id: UBERON:0002887 ! basal amygdaloid nucleus name: basal amygdaloid nucleus synonym: "basolateral amygdaloid nucleus" EXACT [FMA:68855] synonym: "basolateral nucleus (de olmos)" EXACT [] synonym: "intermediate principal nucleus" EXACT [FMA:68855] synonym: "basolateral amygaloid nucleus" EXACT [NIF_GrossAnatomy:birnlex_2692] synonym: "basolateral amygdalar nucleus" EXACT [NIF_GrossAnatomy:birnlex_2692] xref: FMA:68855 ! Basal amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2692 ! Basal amygdaloid nucleus xref: MA:0002921 ! basolateral amygdaloid nucleus xref: ABA:BLA ! Basolateral amygdalar nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001876 ! amygdala relationship: spatially_disjoint_from UBERON:0002023 {source="ABA"} ! claustrum synonym: "nucleus amygdalae basalis lateralis" EXACT LATIN [FMA:TA, FMA:68855] [Term] id: UBERON:0002888 name: lateral part of basal amygdaloid nucleus synonym: "lateral basal nucleus of the amygdala" EXACT [FMA:68857] synonym: "lateral division of the basal nucleus" EXACT [FMA:68857] synonym: "lateral basal nucleus of amygdala" EXACT [NIF_GrossAnatomy:birnlex_2695] synonym: "lateral division of basal nucleus" EXACT [NIF_GrossAnatomy:birnlex_2695] xref: FMA:68857 ! Lateral part of basal amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2695 ! Lateral part of basal amygdaloid nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002887 ! basal amygdaloid nucleus [Term] id: UBERON:0002889 name: medial part of basal amygdaloid nucleus synonym: "basomedial amygdaloid nucleus" EXACT [FMA:68858, MA:0002922] synonym: "medial basal nucleus of amygdala" EXACT [FMA:68858] synonym: "medial division of basal nucleus" EXACT [FMA:68858] synonym: "basomedial amygdalar nucleus" EXACT [ABA:BMA] xref: FMA:68858 ! Medial part of basal amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2696 ! Medial part of basal amygdaloid nucleus xref: MA:0002922 ! basomedial amygdaloid nucleus xref: ABA:BMA ! Basomedial amygdalar nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002887 ! basal amygdaloid nucleus synonym: "nucleus amygdalae basalis medialis" EXACT LATIN [FMA:TA, FMA:68858] [Term] id: UBERON:0002890 name: anterior amygdaloid area synonym: "anterior amygaloid area" EXACT [NIF_GrossAnatomy:birnlex_2698] synonym: "anterior amygdalar area" EXACT [NIF_GrossAnatomy:birnlex_2698] xref: FMA:61861 ! Anterior amygdaloid area xref: NIF_GrossAnatomy:birnlex_2698 ! Anterior amygdaloid area xref: MA:0002919 ! anterior amygdaloid area xref: ABA:AAA ! Anterior amygdalar area xref: BM:Tel-Am-AAA ! anterior amygdaloid area is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001876 ! amygdala [Term] id: UBERON:0002891 name: cortical amygdaloid nucleus synonym: "posterior cortical nucleus of amygdala" EXACT [FMA:61862] synonym: "posterior cortical amygdaloid nucleus" EXACT [NIF_GrossAnatomy:birnlex_2700] synonym: "nucleus amygdalae corticalis" RELATED [BTO:0002703] xref: FMA:61862 ! Cortical amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2700 ! Cortical amygdaloid nucleus xref: BTO:0002703 ! cortical amygdaloid nucleus xref: MA:0002924 ! cortical amygdaloid nucleus xref: EV:0100193 ! cortical amygdaloid nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001876 ! amygdala [Term] id: UBERON:0002892 name: medial amygdaloid nucleus synonym: "medial nucleus of amygdala" EXACT [FMA:74046] synonym: "medial amygalar nucleus" EXACT [NIF_GrossAnatomy:birnlex_2701] synonym: "nucleus amygdalae medialis" RELATED [BTO:0002702] xref: FMA:74046 ! Medial amygdaloid nucleus xref: NIF_GrossAnatomy:birnlex_2701 ! Medial amygdaloid nucleus xref: BTO:0002702 ! medial amygdaloid nucleus xref: MA:0002927 ! medial amygdaloid nucleus xref: EV:0100192 ! medial amygdaloid nucleus xref: BM:Tel-Am-AME ! medial nucleus of amygdala is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001876 ! amygdala [Term] id: UBERON:0013201 ! olfactory pathway name: olfactory pathway def: "Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the olfactory nerve; olfactory bulb; olfactory tract, olfactory tubercle, anterior perforated substance, and olfactory cortex. The term rhinencephalon is restricted to structures in the CNS receiving fibers from the olfactory bulb." [MESH:A08.186.211.577.699] synonym: "anterior perforated substance" RELATED [MESH:A08.186.211.577.699] synonym: "rhinencephalon" RELATED [MESH:A08.186.211.577.699] is_a: UBERON:0000122 ! neuron projection bundle relationship: part_of UBERON:0005725 ! olfactory system relationship: part_of UBERON:0000349 ! limbic system relationship: overlaps UBERON:0001579 ! olfactory nerve relationship: overlaps UBERON:0001883 ! olfactory tubercle relationship: overlaps UBERON:0002264 ! olfactory bulb relationship: overlaps UBERON:0002265 ! olfactory tract relationship: overlaps UBERON:0002894 ! olfactory cortex xref: MESH:A08.186.211.577.699 ! olfactory pathway xref: SCTID:281148007 ! Entire olfactory pathway [Term] id: UBERON:0008981 name: rhinencephalon def: "The olfactory region of the brain, located in the cerebrum." [BTO:0002785] is_obsolete: true comment: Obsoleted because The term rhinencephalon has been used to describe different structures at different points in time.[ISBN 0-8493-8631-4]. May refer to: a specific structure in aves; a part of the brain involved with olfaction; synonym: "olfactory brain" RELATED [BTO:0002785] consider: SCTID:361576004 ! Entire rhinencephalon consider: BTO:0002785 ! rhinencephalon [Term] id: UBERON:0002894 name: olfactory cortex def: "The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors[GO]." [Wikipedia:Olfactory_cortex] comment: Editor note - consider relationship: receives_input_from UBERON:0002264 {source="GO"} ! olfactory bulb subset: uberon_slim synonym: "olfactory lobe" RELATED [MA:0000193] synonym: "archaeocortex" RELATED [BTO:0001446] synonym: "archeocortex" RELATED [BTO:0001446] xref: EHDAA:5482 ! olfactory cortex xref: VHOG:0000325 ! olfactory cortex xref: MA:0000193 ! olfactory cortex xref: NIF_GrossAnatomy:birnlex_2707 ! Olfactory cortex xref: BTO:0001446 ! olfactory cortex xref: EHDAA2:0001289 ! olfactory cortex xref: EMAPA:17779 ! olfactory cortex is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0005366 {source="MA"} ! olfactory lobe property_value: homology_notes " (In mammals) Odorant detection is mediated by millions of olfactory sensory neurons located in the olfactory epithelium lining the nasal cavity. These neurons transmit sensory signals to the olfactory bulb of the brain, which in turn sends signals to the olfactory cortex.[well established][VHOG]" xsd:string {external_class="VHOG:0000325", ontology="VHOG", source="DOI:10.1111/j.1753-4887.2004.tb00097.x Buck LB\, Olfactory receptors and odor coding in mammals. Nutrition Reviews (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: external_definition "That portion of the cerebral cortex that, with the palaeocortex, develops in association with the olfactory system, and which is phylogenetically older than the neocortex and lacks its layered structure. The embryonic archaeocortex corresponds to the cortex of the dentate gyrus and hippocampus in mature mammals[BTO:0001446]." xsd:string {source="BTO:0001446"} [Term] id: UBERON:0002264 name: olfactory bulb def: "A bulbous anterior projection of the olfactory lobe that is the place of termination of the olfactory nerves and is especially well developed in lower vertebrates (as fishes)[BTO]. Segment of neural tree organ which is continuous with a set of olfactory nerves and an olfactory tract. In most vertebrates, the olfactory bulb is the most rostral (forward) part of the brain. In humans, however, the olfactory bulb is on the inferior (bottom) side of the brain. The olfactory bulb is supported and protected by the cribriform plate which in mammals, separates it from the olfactory epithelium, and which is perforated by olfactory nerve axons. The bulb is divided into two distinct structures, the main olfactory bulb, and the accessory olfactory bulb[WP]." [Wikipedia:Olfactory_bulb, BTO:0000961] comment: Note that in uberon 'main olfactory bulb' is a separate class, but some ontologies may treat this as partially synonymous. The distinction may only make sense in tetrapods with a vomeronasal organ (olfactory nerves terminate in OB in fishes and in main OB in tetrapods - Butler and Hodos). Development notes: the olfactory bulbs develop as bilateral evaginations from a region of the prosencephalic neural plate intercalated between the septal and the cortical anlagen (Cobos et al. 2001b, Rubenstein et al. 1998). Comparing the structure of the olfactory bulb among vertebrate species, such as the leopard frog and the lab mouse, reveals that they all share the same fundamental layout(WP). subset: uberon_slim subset: vertebrate_core synonym: "olfactory lobe" RELATED [ZFA:0000402] synonym: "bulbus olfactorius" EXACT [Wikipedia:Olfactory_bulb] xref: BTO:0000961 xref: FMA:77624 ! Olfactory bulb xref: GAID:633 ! olfactory bulb xref: VHOG:0000033 ! olfactory bulb xref: MA:0000194 ! olfactory bulb xref: NIF_GrossAnatomy:birnlex_1137 ! Olfactory bulb xref: TAO:0000402 ! olfactory bulb xref: ZFA:0000402 ! olfactory bulb xref: ncithesaurus:Olfactory_Bulb ! Olfactory Bulb xref: EHDAA2:0004705 ! olfactory bulb xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d2/1543%2CVesalius%27OlfactoryBulbs.jpg/200px-1543%2CVesalius%27OlfactoryBulbs.jpg xref: MESH:A08.186.211.577.699.573 ! olfactory bulb xref: EV:0100173 ! olfactory bulb xref: ABA:OLF ! Olfactory bulb xref: BM:Tel-OB ! olfactory bulb is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0005366 ! olfactory lobe relationship: in_lateral_side_of UBERON:0001893 {source="ISBN10:0471888893"} ! telencephalon relationship: capable_of GO:0007608 ! sensory perception of smell relationship: has_part CL:0000626 {source="ZFA"} ! olfactory granule cell relationship: spatially_disjoint_from UBERON:0002421 {source="ABA"} ! hippocampal formation relationship: spatially_disjoint_from UBERON:0001950 {source="ABA"} ! neocortex xref: AAO:0010165 ! olfactory bulb xref: SCTID:279394006 ! Entire olfactory bulb xref: XAO:0004180 ! olfactory bulb synonym: "bulbus olfactorius" RELATED LATIN [Wikipedia:Olfactory_bulb] xref: http://upload.wikimedia.org/wikipedia/commons/f/f9/1543,Vesalius%27OlfactoryBulbs.jpg property_value: external_definition "Part of the telencephalon comprised of anterior outgrowths of either of the cerebral hemispheres in which the olfactory nerve exits.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010165", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The part of the forebrain in which the olfactory nerves end and the olfactory tracts originate. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000033", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The presence of paired evaginated hemispheres and olfactory bulbs in both agnathan and gnathostome radiations suggests that such hemispheres were also present in the common ancestor.[well established][VHOG]" xsd:string {external_class="VHOG:0000033", ontology="VHOG", source="DOI:10.1146/annurev.ne.04.030181.001505 Northcutt RG\, Evolution of the telencephalon in nonmammals. Ann. Rev. Neurosci. (1981)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: external_definition "Segment of neural tree organ which is continuous with a set of olfactory nerves and an olfactory tract[FMA:77624]." xsd:string {source="FMA:77624"} property_value: external_definition "Part of the rostral part of the cerebrum where axons of olfactory cells from the nasal mucosa terminate. Projects onto olfactory parts of pallium via olfactory tracts" xsd:string {source="ISBN10:0471888893"} xref: UMLS:C0028936 [Term] id: UBERON:0009951 name: main olfactory bulb def: "The main olfactory bulb has a multi-layered cellular architecture. In order from surface to the center the layers are: Glomerular layer, External plexiform layer, Mitral cell layer, Internal plexiform layer, Granule cell layer[WP]." [Wikipedia:Olfactory_bulb#Main_olfactory_bulb] comment: Note that the structure in many ontologies called simply 'olfactory bulb' may in fact belong here is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002264 {source="cjm"} ! olfactory bulb relationship: spatially_disjoint_from UBERON:0004069 {source="ABA"} ! accessory olfactory bulb relationship: spatially_disjoint_from UBERON:0002266 {source="ABA"} ! anterior olfactory nucleus relationship: spatially_disjoint_from UBERON:0002893 {source="ABA"} ! nucleus of lateral olfactory tract relationship: spatially_disjoint_from UBERON:0002590 {source="ABA"} ! prepyriform area xref: ABA:MOB ! Main olfactory bulb [Term] id: UBERON:0004069 name: accessory olfactory bulb def: "the forebrain region that coordinates sensory signaling arising from the vomeronasal organ; it is located on the dorsal-posterior portion of the main olfactory bulb, and the axons that leave the accessory olfactory bulb project to targets in the amygdala and hypothalamus" [MP:0009945, Wikipedia:Olfactory_bulb#Accessory_olfactory_bulb] comment: Site of termination of vomeronasal nerve; projects to: other parts of pallial amygdala, medial amygdala, subpallial nucleus (Butler and Hodos) synonym: "accessory olfactory formation" RELATED [MA:0000966] synonym: "olfactory bulb accessory nucleus" EXACT [NIF_GrossAnatomy:nlx_anat_20090453] xref: MA:0000966 ! accessory olfactory bulb xref: NIF_GrossAnatomy:nlx_anat_20090453 ! Olfactory bulb accessory nucleus xref: BTO:0004797 ! accessory olfactory bulb xref: ABA:AOB ! Accessory olfactory bulb is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002264 {source="cjm"} ! olfactory bulb relationship: overlaps UBERON:0009121 {source="ISBN10:0471888893"} ! vomeronasal nerve relationship: spatially_disjoint_from UBERON:0002266 {source="ABA"} ! anterior olfactory nucleus relationship: spatially_disjoint_from UBERON:0002893 {source="ABA"} ! nucleus of lateral olfactory tract relationship: spatially_disjoint_from UBERON:0002590 {source="ABA"} ! prepyriform area [Term] id: UBERON:0005366 ! olfactory lobe name: olfactory lobe def: "Olfactory apparatus on the lower surface of the frontal lobe of the brain. It consists of the olfactory bulb, tract, and trigone[BTO]." [BTO:0001362] xref: MA:0002413 ! olfactory lobe xref: BTO:0001362 ! olfactory lobe xref: EFO:0000108 ! olfactory lobe xref: EHDAA2_RETIRED:0001294 ! olfactory lobe xref: EHDAA:5480 ! olfactory lobe [part_of: "telencephalon"] xref: EMAPA:17778 ! olfactory lobe xref: VHOG:0000833 ! olfactory lobe [broader: "telencephalon"] xref: MA:0002413 ! olfactory lobe [part_of: "telencephalon"] xref: MIAA:0000116 ! olfactory lobe [SYNONYM: "olfactory bulb" (related)] [broader: "forebrain"] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001893 ! telencephalon xref: ncithesaurus:Olfactory_Lobe ! Olfactory Lobe property_value: homology_notes " (In mammals) Odorant detection is mediated by millions of olfactory sensory neurons located in the olfactory epithelium lining the nasal cavity. These neurons transmit sensory signals to the olfactory bulb of the brain, which in turn sends signals to the olfactory cortex.[well established][VHOG]" xsd:string {external_class="VHOG:0000833", ontology="VHOG", source="DOI:10.1111/j.1753-4887.2004.tb00097.x Buck LB\, Olfactory receptors and odor coding in mammals. Nutrition Reviews (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: external_definition "Part of the telencephalon, comprised of paired anterior outgrowths of either of the cerebral hemispheres in which the olfactory nerve exits. In Xenopus,the olfactory bulbs begin to fuse at NF stage 50, fusion is complete around NF stage 58. The cerebral vein loops around the olfactory bulb by NF stage 43[XAO:0004180]." xsd:string {source="XAO:0004180"} xref: UMLS:C0178780 [Term] id: UBERON:0002922 name: olfactory trigone def: "The olfactory trigone is a small triangular area in front of the anterior perforated substance. Its apex, directed forward, occupies the posterior part of the olfactory sulcus, and is brought into view by throwing back the olfactory tract. [WP,unvetted]." [Wikipedia:Olfactory_trigone] subset: uberon_slim synonym: "trigonum olfactorium" EXACT [NIF_GrossAnatomy:birnlex_4042] synonym: "trigonum olfactorium" RELATED LATIN [Wikipedia:Olfactory_trigone] xref: FMA:74883 ! Olfactory trigone xref: NIF_GrossAnatomy:birnlex_4042 ! Olfactory trigone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray732.png/200px-Gray732.png is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0005366 {source="BTO-def"} ! olfactory lobe xref: ncithesaurus:Trigonum_Olfactorium ! Trigonum Olfactorium xref: SCTID:369102007 ! Entire olfactory trigone xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray732.png xref: UMLS:C0228279 [Term] id: UBERON:0005387 alt_id: UBERON:0011916 name: olfactory glomerulus def: "One of the small globular masses of dense neuropil in the olfactory bulb, containing the first synapse in the olfactory pathway[BTO]. a spherical structure located in the olfactory bulb of the brain where the synapses form between the olfactory nerve terminals and dendrites of mitral, periglomerular and tufted cells. Each glomerulus is surrounded by periglomerular neurons and glial cells which gives it an oval shape.[1][2] All glomeruli are located near the surface of the olfactory bulb. In mammals, glomeruli typically range between 50-120 µm in diameter and number between 1800 and 2400 depending on the species.[1][2] Each glomerulus is composed of two compartments, the olfactory nerve zone and the non-olfactory nerve zone. The olfactory nerve zone is composed of preterminals and terminals of the olfactory nerve and is where the olfactory receptor cells make synapses on their targets.[2] The non-olfactory nerve zone is composed of the dendritic processes of intrinsic neurons and is where dendrodendritic interactions between intrinsic neurons occur.[2] It is the first site for synaptic processing of odor information coming from the nose. It is made up of a globular tangle of axons from the olfactory receptor neurons in the olfactory epithelium, and dendrites from the mitral cell as well as from juxtaglomerular cells that include tufted cells, periglomerular cells, short axon cells, and astrocytes[WP]." [Dorlands_Medical_Dictionary:MerckMedicus, Wikipedia:Glomerulus_(olfaction)] comment: subcellular component, realm of GO? synonym: "olfactory glomeruli" EXACT PLURAL [] synonym: "olfactory bulb glomerulus" EXACT [OBOL:automatic] synonym: "glomerulus of olfactory bulb" EXACT [OBOL:automatic] intersection_of: UBERON:0001047 ! neural glomerulus intersection_of: part_of UBERON:0002264 ! olfactory bulb xref: NIF_Subcellular:nlx_subcell_20090503 ! Olfactory glomerulus xref: BTO:0003653 ! olfactory glomerulus [Term] id: UBERON:0002728 ! entorhinal area name: entorhinal area def: "Component of the temporal lobe on the mesial surface. The rostral and caudal boundaries of the entorhinal cortex are the rostral end of the collateral sulcus and the caudal end of the amygdala respectively. The medial boundary is the medial aspect of the temporal lobe and the lateral boundary is the collateral sulcus. (DK)." [NIF_GrossAnatomy:birnlex_1508, Wikipedia:Entorhinal_cortex] comment: todo - check area vs complex. ABA:ENT this is part of the hippocampal formation via retrohippocampal region subset: uberon_slim synonym: "Brodmann's area 28" RELATED [BTO:0002650] synonym: "entorhinal cortex" RELATED INCONSISTENT [NIF_GrossAnatomy:birnlex_1508] xref: FMA:72356 ! Entorhinal area xref: NIF_GrossAnatomy:birnlex_1508 ! Entorhinal cortex xref: EFO:0001920 ! entorhinal cortex xref: GAID:636 ! entorhinal cortex xref: BTO:0002650 ! entorhinal area xref: MESH:A08.186.211.577.710.225 ! entorhinal cortex xref: ABA:ENT ! Entorhinal area xref: BM:Tel-Cx-ENT ! entorhinal cortex is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002973 {source="FMA"} ! parahippocampal gyrus relationship: part_of UBERON:0004725 {source="BTO"} ! piriform cortex relationship: has_function_in GO:0007613 {source="BTO"} ! memory relationship: spatially_disjoint_from UBERON:0004683 {source="ABA"} ! parasubiculum relationship: spatially_disjoint_from UBERON:0001953 {source="ABA"} ! presubiculum relationship: spatially_disjoint_from UBERON:0002191 {source="ABA"} ! subiculum xref: SCTID:369099007 ! Entire entorhinal cortex xref: ncithesaurus:Entorhinal_Cortex ! entorhinal cortex xref: http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray-Brodman-Entorhinal_Cortex_EC_.png xref: UMLS:C0175196 [Term] id: UBERON:0007224 name: medial entorhinal cortex def: "The entorhinal cortex (EC) is an important memory center in the brain. In rodents, the EC is located at the caudal end of the temporal lobe. In primates it is located at the rostral end of the temporal lobe and stretches dorsolaterally. It is usually divided into medial and lateral regions with three bands with distinct properties and connectivity running perpendicular across the whole area." [BTO:0004347] xref: BTO:0004346 ! medial entorhinal cortex xref: MA:0000922 ! medial entorhinal cortex is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002895 ! secondary olfactory cortex relationship: part_of UBERON:0002728 ! entorhinal area [Term] id: UBERON:0007225 name: lateral entorhinal cortex def: "The entorhinal cortex (EC) is an important memory center in the brain. In rodents, the EC is located at the caudal end of the temporal lobe. In primates it is located at the rostral end of the temporal lobe and stretches dorsolaterally. It is usually divided into medial and lateral regions with three bands with distinct properties and connectivity running perpendicular across the whole area." [BTO:0004347] synonym: "Entorhinal area, lateral part" EXACT [ABA:ENTl] xref: BTO:0004347 ! lateral entorhinal cortex xref: MA:0000911 ! lateral entorhinal cortex xref: ABA:ENTl ! Entorhinal area, lateral part is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002895 ! secondary olfactory cortex relationship: part_of UBERON:0002728 ! entorhinal area [Term] id: UBERON:0013589 name: koniocortex def: "Regions of the cerebal cortex characterized by a particularly well-developed inner granular layer (layer 4); this type of cerebral cortex is represented by the primary sensory Brodmann area 17 of the visual cortex, Brodmann areas 1–3 of the somatic sensory cortex, and Brodmann area 41 of the auditory cortex." [http://www.medilexicon.com/medicaldictionary.php?t=47303] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000956 ! cerebral cortex [Term] id: UBERON:0002896 name: telodiencephalic fissure synonym: "telo-diencephalic fissure" EXACT [FMA:83726] xref: FMA:83726 ! Telodiencephalic fissure xref: NIF_GrossAnatomy:birnlex_4001 ! Telodiencephalic fissure is_a: UBERON:0000464 ! anatomical space [Term] id: UBERON:0002897 name: cistern of lamina terminalis synonym: "lamina terminalis cistern" EXACT [FMA:74516] synonym: "cisterna lamina terminalis" EXACT [NIF_GrossAnatomy:birnlex_4002] xref: FMA:74516 ! Cistern of lamina terminalis xref: NIF_GrossAnatomy:birnlex_4002 ! Cistern of lamina terminalis xref: ncithesaurus:Lamina_Terminalis_Cistern ! Lamina Terminalis Cistern is_a: UBERON:0004050 ! subarachnoid cistern xref: SCTID:12692002 ! Entire cisterna lamina terminalis xref: UMLS:C0228153 [Term] id: UBERON:0002898 name: chiasmatic cistern def: "In front, the cisterna interpeduncularis extends forward across the optic chiasma, forming the cistern of chiasma or chiasmatic cistern, and on to the upper surface of the corpus callosum, for the arachnoid stretches across from one cerebral hemisphere to the other immediately beneath the free border of the falx cerebri, and thus leaves a space in which the anterior cerebral arteries are contained. The 'leaf' or extension of the chiasmatic cistern above the chiasma, which is separated from the optic recess of the third ventricle by the thin lamina terminalis, has been called the suprachiasmatic cistern. As spaces filled with freely circulating cerebrospinal fluid, cisterns receive little direct study, but are mentioned in pathological conditions. Cysts and tumors of the lamina terminalis extend into the suprachiasmatic cistern, as can pituitary tumors, or the cistern can be partially or completely effaced by injury and hematoma or by blockage of the cerebral aqueduct. [WP,unvetted]." [Wikipedia:Chiasmatic_cistern] subset: uberon_slim synonym: "cisterna chiasmatica" EXACT [NIF_GrossAnatomy:birnlex_4003] synonym: "cisterna chiasmatis" EXACT [NIF_GrossAnatomy:birnlex_4003] xref: FMA:74515 ! Chiasmatic cistern xref: NIF_GrossAnatomy:birnlex_4003 ! Chiasmatic cistern xref: ncithesaurus:Chiasmatic_Cistern ! Chiasmatic Cistern xref: EMAPA:25081 ! cisterna chiasmatica of subarachnoid space of arachnoid mater of meninges of diencephalon of forebrain xref: EMAPA:19057 ! cisterna chiasmatica of subarachnoid space of meninges of diencephalon of forebrain xref: EMAPA:19150 ! cisterna chiasmatica of subarachnoid space of meninges of midbrain is_a: UBERON:0004050 ! subarachnoid cistern xref: SCTID:47947006 ! Entire cisterna chiasmatica synonym: "cisterna chiasmatica" RELATED LATIN [Wikipedia:Chiasmatic_cistern] xref: UMLS:C0228152 [Term] id: UBERON:0002899 name: hippocampal sulcus def: "The hippocampal sulcus, also known as the hippocampal fissure, is a sulcus that separates the dentate gyrus from the subiculum and the CA1 field in the hippocampus. [WP,unvetted]." [Wikipedia:Hippocampal_sulcus] comment: AO notes - two classes in ncit (in general ncit distinguishes between fissure and sulcus, whereas FMA treats these as exact synonyms) subset: uberon_slim synonym: "dentate fissure" EXACT [FMA:83747] synonym: "hippocampal fissure" EXACT [FMA:83747] synonym: "sulcus hippocampi" EXACT [NIF_GrossAnatomy:birnlex_4004] xref: FMA:83747 ! Hippocampal sulcus xref: NIF_GrossAnatomy:birnlex_4004 ! Hippocampal sulcus xref: ncithesaurus:Hippocampal_Fissure ! Hippocampal Fissure xref: NIF_GrossAnatomy:birnlex_4004 ! Hippocampal sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/31/Hippocampus_%28brain%29.jpg/200px-Hippocampus_%28brain%29.jpg is_a: UBERON:0000093 ! sulcus xref: SCTID:369101000 ! Entire hippocampal fissure synonym: "sulcus hippocampalis, sulcus hippocampi" RELATED LATIN [Wikipedia:Hippocampal_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/3/31/Hippocampus_%28brain%29.jpg xref: UMLS:C0228251 [Term] id: UBERON:0002900 name: transverse occipital sulcus synonym: "sulcus occipitalis transversus" EXACT [NIF_GrossAnatomy:birnlex_4013] xref: FMA:83786 ! Transverse occipital sulcus xref: NIF_GrossAnatomy:birnlex_4013 ! Transverse occipital sulcus xref: BTO:0003786 ! transverse occipital sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002901 name: posterior calcarine sulcus synonym: "postcalcarine sulcus" EXACT [FMA:83787] synonym: "posterior calcarine fissure" EXACT [FMA:83787] synonym: "posterior part of calcarine sulcus" EXACT [FMA:83787] synonym: "sulcus calcarinus posterior" EXACT [NIF_GrossAnatomy:birnlex_4015] xref: FMA:83787 ! Posterior calcarine sulcus xref: NIF_GrossAnatomy:birnlex_4015 ! Posterior calcarine sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002903 name: lunate sulcus synonym: "lunate fissure" EXACT [FMA:83788] synonym: "sulcus lunatus" EXACT [NIF_GrossAnatomy:birnlex_4017] synonym: "sulcus simialis" EXACT [NIF_GrossAnatomy:birnlex_4017] xref: FMA:83788 ! Lunate sulcus xref: NIF_GrossAnatomy:birnlex_4017 ! Lunate sulcus xref: ncithesaurus:Lunate_Sulcus ! Lunate Sulcus xref: BM:Tel-Cx-LUS ! lunate sulcus is_a: UBERON:0000093 ! sulcus xref: UMLS:C0262278 [Term] id: UBERON:0002904 name: lateral occipital sulcus def: "In the occipital lobe, the lateral occipital sulcus extends from behind forward, and divides the lateral surface of the occipital lobe into a superior and an inferior gyrus, which are continuous in front with the parietal and temporal lobes. [WP,unvetted]." [Wikipedia:Lateral_occipital_sulcus] subset: uberon_slim synonym: "sulcus occipitalis lateralis" EXACT [NIF_GrossAnatomy:birnlex_4018] xref: FMA:83785 ! Lateral occipital sulcus xref: NIF_GrossAnatomy:birnlex_4018 ! Lateral occipital sulcus xref: ncithesaurus:Lateral-occipital_Sulcus ! Lateral-Occipital Sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2c/Gray727_lateral-occipital_sulcus.svg/200px-Gray727_lateral-occipital_sulcus.svg.png is_a: UBERON:0000093 ! sulcus xref: SCTID:369219003 ! Entire lateral occipital sulcus xref: http://upload.wikimedia.org/wikipedia/commons/2/2c/Gray727_lateral-occipital_sulcus.svg xref: UMLS:C0228229 [Term] id: UBERON:0002905 name: intralingual sulcus synonym: "sulcus intralingualis" EXACT [NIF_GrossAnatomy:birnlex_4019] xref: FMA:83789 ! Intralingual sulcus xref: NIF_GrossAnatomy:birnlex_4019 ! Intralingual sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002906 name: anterior occipital sulcus synonym: "sulcus occipitalis anterior" EXACT [NIF_GrossAnatomy:birnlex_4023] synonym: "ascending limb of the inferior temporal sulcus" EXACT [NIF_GrossAnatomy:birnlex_4023] synonym: "posterior inferior temporal sulcus" EXACT [NIF_GrossAnatomy:birnlex_4023] synonym: "sulci occipitales superiores" EXACT [NIF_GrossAnatomy:birnlex_4023] synonym: "sulcus annectans" EXACT [NIF_GrossAnatomy:birnlex_4023] xref: FMA:75758 ! Anterior occipital sulcus xref: NIF_GrossAnatomy:birnlex_4023 ! Anterior occipital sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002907 name: superior postcentral sulcus synonym: "postcentral dimple" EXACT [FMA:83775] synonym: "sulcus postcentralis superior" EXACT [NIF_GrossAnatomy:birnlex_4025] xref: FMA:83775 ! Superior postcentral sulcus xref: NIF_GrossAnatomy:birnlex_4025 ! Superior postcentral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002908 name: subparietal sulcus synonym: "splenial sulcus" EXACT [FMA:83777] synonym: "suprasplenial sulcus" EXACT [FMA:83777] synonym: "sulcus subparietalis" EXACT [NIF_GrossAnatomy:birnlex_4026] xref: FMA:83777 ! Subparietal sulcus xref: NIF_GrossAnatomy:birnlex_4026 ! Subparietal sulcus xref: BM:Tel-Cx-SPS ! subparietal sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279352008 ! Entire subparietal sulcus [Term] id: UBERON:0002909 name: posterior subcentral sulcus synonym: "sulcus subcentralis posterior" EXACT [NIF_GrossAnatomy:birnlex_4027] xref: FMA:83778 ! Posterior subcentral sulcus xref: NIF_GrossAnatomy:birnlex_4027 ! Posterior subcentral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002910 name: posterior ascending limb of lateral sulcus synonym: "ascending terminal ramus of sylvian fissure" EXACT [] synonym: "posterior ascending limb of lateral fissure" EXACT [FMA:83761] synonym: "posterior ramus of lateral cerebral sulcus" EXACT [FMA:83761] synonym: "ramus posterior ascendens fissurae lateralis" EXACT [NIF_GrossAnatomy:birnlex_4028] xref: FMA:83761 ! Posterior ascending limb of lateral sulcus xref: NIF_GrossAnatomy:birnlex_4028 ! Posterior ascending limb of lateral sulcus is_a: UBERON:0000464 ! anatomical space synonym: "ramus posterior sulci lateralis cerebri" EXACT LATIN [FMA:TA, FMA:83761] [Term] id: UBERON:0002912 name: marginal sulcus def: "The marginal sulcus is the portion of the cingulate sulcus adjacent to the paracentral lobule and the precuneus. It is sometimes known as the 'marginal part of the cingulate sulcus'. [WP,unvetted]." [Wikipedia:Marginal_sulcus, Wikipedia:Marginal_sulcus] subset: uberon_slim synonym: "marginal branch of cingulate sulcus" EXACT [FMA:83773] synonym: "marginal ramus of cingulate sulcus" EXACT [FMA:83773] synonym: "ramus marginalis sulci cingulati" EXACT [NIF_GrossAnatomy:birnlex_4030] xref: FMA:83773 ! Marginal sulcus xref: NIF_GrossAnatomy:birnlex_4030 ! Marginal sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d0/Gray727_marginal_sulcus.svg/200px-Gray727_marginal_sulcus.svg.png is_a: UBERON:0000093 ! sulcus synonym: "ramus marginalis sulci cinguli" EXACT LATIN [FMA:TA, FMA:83773] xref: SCTID:279351001 ! Marginal sulcus synonym: "ramus marginalis; sulcus marginalis" RELATED LATIN [Wikipedia:Marginal_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/d/d0/Gray727_marginal_sulcus.svg [Term] id: UBERON:0002913 name: intraparietal sulcus def: "The intraparietal sulcus (IPS) is located on the lateral surface of the parietal lobe, and consists of an oblique and a horizontal portion. The IPS contains a series of functionally distinct subregions that have been intensively investigated using both single cell neurophysiology in primates and human functional neuroimaging. Its principal functions are related to perceptual-motor coordination (for directing eye movements and reaching) and visual attention. The IPS is also thought to play a role in other functions, including processing symbolic numerical information, visuospatial working memory and interpreting the intent of others. [WP,unvetted]." [Wikipedia:Intraparietal_sulcus] subset: uberon_slim synonym: "interparietal fissure" EXACT [FMA:83772] synonym: "intraparietal fissure" EXACT [FMA:83772] synonym: "sulcus interparietalis" EXACT [NIF_GrossAnatomy:birnlex_4031] synonym: "intraparietal sulcus of Turner" RELATED [BTO:0003787] synonym: "sulcus intraparietalis" RELATED [BTO:0003787] synonym: "Turner sulcus" RELATED [BTO:0003787] xref: FMA:83772 ! Intraparietal sulcus xref: NIF_GrossAnatomy:birnlex_4031 ! Intraparietal sulcus xref: ncithesaurus:Intraparietal_Sulcus ! Intraparietal Sulcus xref: BTO:0003787 ! intraparietal sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2a/Gray726_intraparietal_sulcus.svg/200px-Gray726_intraparietal_sulcus.svg.png xref: BM:Tel-Cx-IPS ! intraparietal sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279338006 ! Entire intraparietal sulcus synonym: "sulcus intraparietalis" RELATED LATIN [Wikipedia:Intraparietal_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/2/2a/Gray726_intraparietal_sulcus.svg xref: UMLS:C0228213 [Term] id: UBERON:0002914 name: inferior postcentral sulcus synonym: "sulcus postcentralis inferior" EXACT [NIF_GrossAnatomy:birnlex_4032] xref: FMA:83776 ! Inferior postcentral sulcus xref: NIF_GrossAnatomy:birnlex_4032 ! Inferior postcentral sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002915 name: postcentral sulcus def: "The postcentral sulcus of the parietal lobe lies parallel to, and behind, the central sulcus in the human brain. (A sulcus is one of the prominent grooves on the surface of the brain. ) The postcentral sulcus divides the postcentral gyrus from the remainder of the parietal lobe. [WP,unvetted]." [Wikipedia:Postcentral_sulcus] subset: uberon_slim synonym: "postcentral fissure of cerebral hemisphere" EXACT [FMA:83774] synonym: "postcentral fissure-1" EXACT [FMA:83774] synonym: "structure of postcentral sulcus" EXACT [NIF_GrossAnatomy:birnlex_4033] synonym: "sulcus postcentralis" EXACT [NIF_GrossAnatomy:birnlex_4033] xref: FMA:83774 ! Postcentral sulcus xref: NIF_GrossAnatomy:birnlex_4033 ! Postcentral sulcus xref: ncithesaurus:Postcentral_Sulcus ! Postcentral Sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6c/Postcentral_sulcus.png/200px-Postcentral_sulcus.png xref: BM:Tel-Cx-PoCS ! postcentral sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279339003 ! Entire postcentral sulcus synonym: "sulcus postcentralis" RELATED LATIN [Wikipedia:Postcentral_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Postcentral_sulcus.png xref: UMLS:C0228212 [Term] id: UBERON:0002916 name: central sulcus def: "The central sulcus is a fold in the cerebral cortex of brains in vertebrates. Also called the central fissure, it was originally called the fissure of Rolando or the Rolandic fissure, after Luigi Rolando. The central sulcus is a prominent landmark of the brain, separating the parietal lobe from the frontal lobe and the primary motor cortex from the primary somatosensory cortex. [WP,unvetted]." [Wikipedia:Central_sulcus] subset: uberon_slim synonym: "central cerebral sulcus" EXACT [FMA:83752] synonym: "central fissure" EXACT [FMA:83752] synonym: "central sulcus of rolando" EXACT [] synonym: "fissure of rolando" EXACT [] synonym: "sulcus of rolando" EXACT [] synonym: "rolandic fissure" EXACT [NIF_GrossAnatomy:birnlex_4035] synonym: "sulcus centralis" EXACT [NIF_GrossAnatomy:birnlex_4035] synonym: "sulcus centralis cerebri" EXACT [NIF_GrossAnatomy:birnlex_4035] synonym: "sulcus centralis (rolandi)" EXACT [NIF_GrossAnatomy:birnlex_4035] xref: FMA:83752 ! Central sulcus xref: NIF_GrossAnatomy:birnlex_4035 ! Central sulcus xref: ncithesaurus:Central_Sulcus_of_Rolando ! Central Sulcus of Rolando xref: OpenCyc:Mx4rvjMKxpwpEbGdrcN5Y29ycA ! central sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b6/Central_sulcus.png/200px-Central_sulcus.png xref: BM:Tel-Cx-CS ! central sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279340001 ! Entire central sulcus synonym: "sulcus centralis cerebri" RELATED LATIN [Wikipedia:Central_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/8/8e/Gray726_central_sulcus.svg [Term] id: UBERON:0002917 name: regional part of inferior colliculus subset: non_informative def: "A regional part of brain that is part of a inferior colliculus [Automatically generated definition]." [OBOL:automatic] synonym: "inferior colliculus segment" EXACT [FMA:77871] synonym: "segment of inferior colliculus" EXACT [NIF_GrossAnatomy:birnlex_4036] xref: FMA:77871 ! Segment of inferior colliculus xref: NIF_GrossAnatomy:birnlex_4036 ! Regional part of inferior colliculus is_a: UBERON:0002966 ! regional part of midbrain tectum intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001946 ! inferior colliculus [Term] id: UBERON:0002918 name: medial parabrachial nucleus def: "The Medial parabrachial nucleus is a nucleus of the pons which constitutes part of the pneumotaxic center. It gets its name from its location relative to the superior cerebellar peduncles, which is also known as the 'brachia conjunctiva'. [WP,unvetted]." [Wikipedia:Medial_parabrachial_nucleus, Wikipedia:Medial_parabrachial_nucleus] subset: uberon_slim xref: FMA:72480 ! Medial parabrachial nucleus xref: NIF_GrossAnatomy:birnlex_4038 ! Medial parabrachial nucleus is_a: UBERON:0002308 ! nucleus of brain synonym: "nucleus parabrachialis medialis" RELATED LATIN [Wikipedia:Medial_parabrachial_nucleus] [Term] id: UBERON:0002919 name: anterior parolfactory sulcus synonym: "paraolfactory sulcus" EXACT [FMA:83744] synonym: "paraolfactory sulci" EXACT PLURAL [NIF_GrossAnatomy:birnlex_4039] synonym: "sulcus parolfactorius anterior" EXACT [NIF_GrossAnatomy:birnlex_4039] xref: FMA:83744 ! Anterior parolfactory sulcus xref: NIF_GrossAnatomy:birnlex_4039 ! Anterior parolfactory sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002920 name: callosal sulcus def: "The callosal sulcus is a sulcus in the brain between the cingulate gyrus and corpus callosum, below the longitudinal cerebral fissure. [WP,unvetted]." [Wikipedia:Callosal_sulcus] subset: uberon_slim synonym: "sulcus of corpus callosum" EXACT [FMA:83743] synonym: "sulcus corporis callosi" EXACT [NIF_GrossAnatomy:birnlex_4040] xref: FMA:83743 ! Callosal sulcus xref: NIF_GrossAnatomy:birnlex_4040 ! Callosal sulcus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/43/Gray727_sulcus_of_the_corpus_callosum.svg/200px-Gray727_sulcus_of_the_corpus_callosum.svg.png is_a: UBERON:0000093 ! sulcus xref: SCTID:279349000 ! Callosal sulcus synonym: "sulcus corporis callosi" RELATED LATIN [Wikipedia:Callosal_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/4/43/Gray727_sulcus_of_the_corpus_callosum.svg [Term] id: UBERON:0002921 name: longitudinal fissure def: "The deep groove which separates the two hemispheres of the vertebrate brain. The falx cerebri, a dural brain covering, lies within the medial longitudinal fissure. [WP,unvetted]." [Wikipedia:Medial_longitudinal_fissure] subset: uberon_slim synonym: "hemispheric sulcus" EXACT [FMA:83727] synonym: "interhemispheric fissure" EXACT [FMA:83727] synonym: "longitudinal cerebral fissure" EXACT [FMA:83727] synonym: "longitudinal sulcus" EXACT [FMA:83727] synonym: "medial longitudinal fissure" EXACT [FMA:83727] synonym: "sagittal fissure" EXACT [FMA:83727] synonym: "fissura interhemispherica" EXACT [NIF_GrossAnatomy:birnlex_4041] synonym: "fissura longitudinalis cerebrales" EXACT [NIF_GrossAnatomy:birnlex_4041] synonym: "fissura longitudinalis cerebri" EXACT [NIF_GrossAnatomy:birnlex_4041] synonym: "fissura longitudinalis magna" EXACT [NIF_GrossAnatomy:birnlex_4041] synonym: "longitudinal fissure of the cerebrum" EXACT [NIF_GrossAnatomy:birnlex_4041] synonym: "longitudinal fissure of hemisphere" EXACT [NIF_GrossAnatomy:birnlex_4041] xref: FMA:83727 ! Longitudinal fissure xref: NIF_GrossAnatomy:birnlex_4041 ! Longitudinal fissure xref: ncithesaurus:Longitudinal_Fissure ! Longitudinal Fissure xref: OpenCyc:Mx4rwJlWu5wpEbGdrcN5Y29ycA ! longitudinal fissure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/92/Hemispheres.png/200px-Hemispheres.png is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0000315 ! subarachnoid space xref: SCTID:369225004 ! Entire longitudinal cerebral fissure xref: UMLS:C0228186 [Term] id: UBERON:0002923 name: posterior parolfactory sulcus xref: FMA:83745 ! Posterior parolfactory sulcus xref: NIF_GrossAnatomy:birnlex_4043 ! Posterior parolfactory sulcus is_a: UBERON:0000093 ! sulcus [Term] id: UBERON:0002924 name: terminal nerve def: "The terminal nerve, located anterior to cranial nerve I, is comprised of a group of cells with somata adjacent to the olfactory bulb and processes that extend anteriorly to the olfactory epithelium and posteriorly to the telencephalon. In teleost fish an additional group of axons extends along the optic tract and delivers putative neuromodulators to the retina. It is thought to develop from cranial neural crest." [PMID:15821344, ZFIN:ZDB-PUB-041202-1, Wikipedia:Terminal_nerve] comment: PMID:2286018 state: 'The presence of an additional cranial nerve (the nervus terminalis or cranial nerve zero) is well documented in many non-human vertebrate species. However, its existence in the adult human has been disputed. The present study focused on the structure and incidence of this nerve in the adult human brain. The nerve was examined post-mortem in 10 adult brains using dissection microscopy, light microscopy, transmission electron microscopy, and immunohistochemistry. In all specimens, the nervus terminalis was identified bilaterally as a microscopic plexus of unmyelinated peripheral nerve fascicles in the subarachnoid space covering the gyrus rectus of the orbital surface of the frontal lobes. The plexus appeared in the region of the cribriform plate of the ethmoid and coursed posteriorly to the vicinity of the olfactory trigone, medial olfactory gyrus, and lamina terminalis. We conclude that the terminal nerve is a common finding in the adult human brain, confirming early light microscopic reports.' subset: uberon_slim synonym: "nervus terminalis" EXACT [ZFA:0001356] synonym: "cranial nerve zero" EXACT [Wikipedia:Terminal_nerve] synonym: "cranial nerve 0" EXACT [Wikipedia:Terminal_nerve] xref: NIF_GrossAnatomy:birnlex_4044 ! terminal nerve xref: ZFA:0001356 ! terminal nerve xref: EFO:0003678 ! terminal nerve is_a: UBERON:0001785 {source="ZFA"} ! cranial nerve xref: TAO:0001356 ! terminal nerve property_value: external_definition "The terminal nerve, located anterior to cranial nerve I, is comprised of a group of cells with somata adjacent to the olfactory bulb and processes that extend anteriorly to the olfactory epithelium and posteriorly to the telencephalon. In teleost fish an additional group of axons extends along the optic tract and delivers putative neuromodulators to the retina. It is thought to develop from cranial neural crest. Whitlock 2004. Also see Grens, Greenwood and Fernald, Brain Behav Evol 2005; 66(1):1-9.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001356", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0002304 name: layer of dentate gyrus comment: This class was created automatically from a combination of ontologies synonym: "dentate gyrus layer" EXACT [] xref: FMA:83678 ! Layer of dentate gyrus xref: MA:0002429 ! dentate gyrus layer is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001885 ! dentate gyrus of hippocampal formation [Term] id: UBERON:0004679 name: dentate gyrus molecular layer synonym: "dentate gyrus molecular layer" EXACT [NIF_GrossAnatomy:birnlex_4127] synonym: "molecular layer of dentate gyrus" EXACT [FMA:83677] xref: FMA:83677 ! molecular layer of dentate gyrus xref: NIF_GrossAnatomy:birnlex_4127 ! Dentate gyrus molecular layer is_a: UBERON:0002304 ! layer of dentate gyrus relationship: part_of UBERON:0001885 ! dentate gyrus of hippocampal formation [Term] id: UBERON:0002928 name: dentate gyrus polymorphic layer xref: MA:0002864 ! dentate gyrus polymorphic layer xref: NIF_GrossAnatomy:birnlex_4128 ! Dentate gyrus polymorphic layer is_a: UBERON:0000200 ! gyrus is_a: UBERON:0002304 ! layer of dentate gyrus [Term] id: UBERON:0002929 name: dentate gyrus pyramidal layer xref: MA:0000948 ! dentate gyrus pyramidal layer is_a: UBERON:0002304 ! layer of dentate gyrus [Term] id: UBERON:0005381 name: dentate gyrus granule cell layer synonym: "granular layer of dentate gyrus" EXACT [FMA:83146] synonym: "DG granule cell layer" EXACT [NIF_GrossAnatomy:birnlex_4129] xref: MA:0000946 ! dentate gyrus granule cell layer xref: NIF_GrossAnatomy:birnlex_4129 ! Dentate gyrus granule cell layer xref: FMA:83146 ! Granular layer of dentate gyrus xref: ABA:DG-sg ! Dentate gyrus, granule cell layer is_a: UBERON:0002304 ! layer of dentate gyrus [Term] id: UBERON:0002930 name: tectopontine tract synonym: "tectopontine fibers" EXACT [FMA:72505] synonym: "tectopontine fibres" EXACT [FMA:72505] xref: FMA:72505 ! Tectopontine tract xref: NIF_GrossAnatomy:birnlex_701 ! Tectopontine tract is_a: UBERON:0002316 ! white matter of neuraxis synonym: "fibrae tectopontinae" EXACT LATIN [FMA:TA, FMA:72505] xref: SCTID:3301002 ! Tectopontine fibers [Term] id: UBERON:0002931 name: dorsal septal nucleus xref: FMA:61877 ! Dorsal septal nucleus xref: NIF_GrossAnatomy:birnlex_704 ! Dorsal septal nucleus is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002932 name: trapezoid body def: "The trapezoid body is part of the acoustic pathway. It is a bundle of fibers and cells in the pontine tegmentum. It consists of fibers arising from the ventral cochlear nucleus. A collection of nerve cells inside forms a trapezoid nucleus. The superior olivary nucleus is situated on the dorsal surface of the trapezoid body. Most nerve fibers pass directly from the superior olivary nuclei to the inferior colliculus. Axons leaving the ventral cochlear nucleus (VCN) form a broad pathway that crosses under the brain stem in the trapezoid body. A thin pathway, the intermediate acoustic stria, also leaves the VCN, merging with the trapezoid body close to the superior olivary complex, where many of its axons synapse. Axons leaving the dorsal cochlear nucleus (DCN) form the dorsal acoustic stria, which reaches primarily the contralateral dorsal nucleus of the lateral lemniscus and the central nucleus of the inferior colliculus. [WP,unvetted]." [Wikipedia:Trapezoid_body] subset: uberon_slim xref: FMA:72487 ! Trapezoid body xref: NIF_GrossAnatomy:birnlex_707 ! Trapezoid body xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Gray760.png/200px-Gray760.png xref: BM:TB ! trapezoid body is_a: UBERON:0002316 ! white matter of neuraxis xref: SCTID:369019006 ! Entire trapezoid body synonym: "corpus trapezoideum" RELATED LATIN [Wikipedia:Trapezoid_body] xref: http://upload.wikimedia.org/wikipedia/commons/b/bb/Gray760.png [Term] id: UBERON:0002933 name: nucleus of anterior commissure synonym: "anterior commissure nucleus" EXACT [FMA:61883] synonym: "bed nucleus of anterior commissure" EXACT [FMA:61883] synonym: "nucleus of commissura anterior" EXACT [FMA:61883] xref: FMA:61883 ! Nucleus of anterior commissure xref: NIF_GrossAnatomy:birnlex_712 ! Nucleus of anterior commissure xref: ABA:BAC ! Bed nucleus of the anterior commissure xref: BM:Tel-ACN ! nucleus of anterior commissure is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002663 ! septal nuclear complex [Term] id: UBERON:0002934 name: ventral oculomotor nucleus synonym: "ventral oculomotor cell column" EXACT [FMA:72422] xref: FMA:72422 ! Ventral oculomotor nucleus xref: NIF_GrossAnatomy:birnlex_713 ! Ventral oculomotor nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002647 name: magnocellular part of medial dorsal nucleus synonym: "dorsomedial thalamic nucleus, magnocellular part" EXACT [FMA:62161] synonym: "magnocellular mediodorsal nucleus" EXACT [FMA:62161] synonym: "magnocellular nucleus of medial dorsal nucleus of thalamus" EXACT [FMA:62161] synonym: "magnocellular part of dorsomedial nucleus" EXACT [FMA:62161] synonym: "magnocellular part of mediodorsal nucleus" EXACT [NIF_GrossAnatomy:birnlex_1262] synonym: "nucleus medialis dorsalis, pars magnocellularis" EXACT [NIF_GrossAnatomy:birnlex_1262] synonym: "nucleus medialis fibrosus" EXACT [NIF_GrossAnatomy:birnlex_1262] synonym: "nucleus medialis fibrosus (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1262] xref: FMA:62161 ! Magnocellular part of medial dorsal nucleus xref: NIF_GrossAnatomy:birnlex_1262 ! Magnocellular part of medial dorsal nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002739 {source="FMA"} ! medial dorsal nucleus synonym: "pars magnocellularis nuclei mediodorsalis thalami" EXACT LATIN [FMA:TA, FMA:62161] [Term] id: UBERON:0002759 name: magnocellular nucleus of medial geniculate body synonym: "medial division of medial geniculate body" EXACT [FMA:62218] synonym: "medial geniculate complex, medial part" EXACT [FMA:62218] synonym: "medial geniculate nucleus, medial part" EXACT [FMA:62218] synonym: "medial magnocellular nucleus of medial geniculate body" EXACT [FMA:62218] synonym: "medial nucleus of medial geniculate body" EXACT [FMA:62218] synonym: "corpus geniculatus mediale, pars magnocelluaris" EXACT [NIF_GrossAnatomy:birnlex_1612] synonym: "magnocelluar nucleus of medial geniculate complex" EXACT [NIF_GrossAnatomy:birnlex_1612] synonym: "nucleus corporis geniculati medialis, pars magnocelluaris" EXACT [NIF_GrossAnatomy:birnlex_1612] synonym: "nucleus geniculatus medialis magnocelluaris (hassler)" EXACT [NIF_GrossAnatomy:birnlex_1612] synonym: "nucleus geniculatus medialis, pars magnocelluaris" EXACT [NIF_GrossAnatomy:birnlex_1612] synonym: "nucleus medialis magnocellularis corporis geniculati medialis" RELATED [BTO:0002672] xref: FMA:62218 ! Magnocellular nucleus of medial geniculate body xref: NIF_GrossAnatomy:birnlex_1612 ! Magnocellular nucleus of medial geniculate body xref: BTO:0002672 ! medial nucleus of medial geniculate body xref: ABA:MGm ! Medial geniculate complex, medial part is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001927 ! medial geniculate body relationship: spatially_disjoint_from UBERON:0002758 {source="ABA"} ! dorsal nucleus of medial geniculate body relationship: spatially_disjoint_from UBERON:0002985 {source="ABA"} ! ventral nucleus of medial geniculate body [Term] id: UBERON:0002935 name: magnocellular part of ventral anterior nucleus synonym: "magnocellular division of ventral anterior nucleus of thalamus" EXACT [FMA:62192] synonym: "ventral anterior nucleus, magnocellular part" EXACT [FMA:62192] synonym: "ventral anterior nucleus, pars magnocellularis" EXACT [FMA:62192] synonym: "ventral anterior thalamic nucleus, magnocellular part" EXACT [FMA:62192] synonym: "magnocellular ventral anterior nucleus" EXACT [NIF_GrossAnatomy:birnlex_716] synonym: "nucleus lateropolaris (magnocellularis)" EXACT [NIF_GrossAnatomy:birnlex_716] synonym: "nucleus lateropolaris magnocellularis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_716] synonym: "nucleus rostralis lateralis situs perifascicularis" EXACT [NIF_GrossAnatomy:birnlex_716] synonym: "nucleus thalamicus ventral anterior, pars magnocellularis" EXACT [NIF_GrossAnatomy:birnlex_716] synonym: "nucleus ventralis anterior, pars magnocellularis" EXACT [NIF_GrossAnatomy:birnlex_716] synonym: "ventroanterior thalamic nucleus, magnocellular part" EXACT [NIF_GrossAnatomy:birnlex_716] xref: FMA:62192 ! Magnocellular part of ventral anterior nucleus xref: NIF_GrossAnatomy:birnlex_716 ! Magnocellular part of ventral anterior nucleus xref: BM:Die-Th-VA-VAmc ! ventral anterior nucleus of thalamus, magnocellular division is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002637 {source="FMA"} ! ventral anterior nucleus synonym: "pars magnocellularis nuclei ventralis anterior thalami" EXACT LATIN [FMA:TA, FMA:62192] [Term] id: UBERON:0002937 name: parvicellular part of ventral anterior nucleus synonym: "ventral anterior nucleus, pars parvicellularis" EXACT [FMA:62191] synonym: "ventral anterior thalamic nucleus, parvicellular part" EXACT [FMA:62191] synonym: "ventralis anterior (jones)" EXACT [] synonym: "nucleus ventralis anterior (dewulf)" EXACT [NIF_GrossAnatomy:birnlex_722] synonym: "nucleus ventralis anterior, pars parvicellularis" EXACT [NIF_GrossAnatomy:birnlex_722] xref: FMA:62191 ! Parvicellular part of ventral anterior nucleus xref: NIF_GrossAnatomy:birnlex_722 ! Parvicellular part of ventral anterior nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002637 {source="FMA"} ! ventral anterior nucleus [Term] id: UBERON:0002936 name: magnocellular part of red nucleus synonym: "paleoruber" EXACT [FMA:72431] synonym: "red nucleus, magnocellular part" EXACT [FMA:72431] xref: FMA:72431 ! Magnocellular part of red nucleus xref: NIF_GrossAnatomy:birnlex_720 ! Magnocellular part of red nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001947 ! red nucleus [Term] id: UBERON:0002938 name: parvocellular part of red nucleus synonym: "neoruber" EXACT [FMA:72430] synonym: "red nucleus, parvocellular part" EXACT [FMA:72430] xref: FMA:72430 ! Parvocellular part of red nucleus xref: NIF_GrossAnatomy:birnlex_725 ! Parvocellular part of red nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001947 ! red nucleus [Term] id: UBERON:0002939 name: ventral posteroinferior nucleus synonym: "ventral posterior inferior nucleus" EXACT [FMA:62199] synonym: "ventral posterior inferior nucleus of thalamus" EXACT [FMA:62199] synonym: "ventral posterior inferior thalamic nucleus" EXACT [FMA:62199] xref: FMA:62199 ! Ventral posteroinferior nucleus xref: NIF_GrossAnatomy:birnlex_728 xref: BTO:0002464 ! ventrobasal complex of thalamus xref: BTO:0004373 ! ventral posterior nucleus (also: UBERON:0002596 'ventral posterior nucleus') xref: BTO:0004374 ! ventral posterior inferior nucleus (also: UBERON:0002596 'ventral posterior nucleus') xref: EV:0100209 ! ventral posterior thalamic nucleus (also: UBERON:0002596 'ventral posterior nucleus') xref: BM:Die-Th-VPI ! ventral posterior inferior nucleus of thalamus (also: UBERON:0002596 'ventral posterior nucleus') is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain synonym: "nucleus ventralis posterior inferior thalami" EXACT LATIN [FMA:TA, FMA:62199] xref: SCTID:369173003 ! Entire ventral posterior inferior nucleus [Term] id: UBERON:0002940 name: anterior column of fornix synonym: "anterior crus of fornix" EXACT [FMA:61966] synonym: "anterior pillar of fornix" EXACT [FMA:61966] xref: FMA:61966 ! Anterior column of fornix xref: NIF_GrossAnatomy:birnlex_731 ! Anterior column of fornix is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002941 name: capsule of red nucleus synonym: "red nuclear capsule" EXACT [FMA:72450] xref: FMA:72450 ! Capsule of red nucleus xref: NIF_GrossAnatomy:birnlex_732 ! Capsule of red nucleus is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001947 ! red nucleus xref: SCTID:369245007 ! Entire capsule of red nucleus [Term] id: UBERON:0002781 name: caudal part of ventral posterolateral nucleus synonym: "ventral posterior lateral nucleus (ilinsky)" EXACT [] synonym: "ventral posterolateral nucleus, caudal part" EXACT [FMA:62206] synonym: "ventral posterolateral thalamic nucleus, caudal part" EXACT [FMA:62206] xref: FMA:62206 ! Caudal part of ventral posterolateral nucleus xref: NIF_GrossAnatomy:birnlex_1681 ! Caudal part of ventral posterolateral nucleus is_a: UBERON:0002020 ! gray matter of neuraxis [Term] id: UBERON:0002942 name: ventral posterolateral nucleus def: "The ventral posterolateral nucleus (VPL) is a nucleus of the thalamus. Together with the ventral posteromedial nucleus (VPM) it constitutes the ventral posterior nucleus. [WP,unvetted]." [Wikipedia:Ventral_posterolateral_nucleus] subset: uberon_slim synonym: "posterolateral ventral nucleus of thalamus" EXACT [FMA:62200] synonym: "ventral posterolateral nucleus of thalamus" EXACT [FMA:62200] synonym: "ventral posterolateral thalamic nucleus" EXACT [FMA:62200] synonym: "nucleus ventralis posterior lateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_737] synonym: "nucleus ventralis posterolateralis" EXACT [NIF_GrossAnatomy:birnlex_737] synonym: "nucleus ventralis posterolateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_737] synonym: "nucleus ventralis thalami posterior lateralis" EXACT [NIF_GrossAnatomy:birnlex_737] synonym: "posterolateral ventral nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_737] synonym: "ventral posterolateral nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_737] xref: FMA:62200 ! Ventral posterolateral nucleus xref: NIF_GrossAnatomy:birnlex_737 ! Ventral posterolateral nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: ABA:VPL ! Ventral posterolateral nucleus of the thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002945 {source="ABA"} ! ventral posteromedial nucleus xref: SCTID:369171001 ! Entire ventral posterolateral nucleus of thalamus synonym: "nucleus ventralis posterolateralis thalami" RELATED LATIN [Wikipedia:Ventral_posterolateral_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png [Term] id: UBERON:0002943 name: lingual gyrus def: "The lingual gyrus of the occipital lobe lies between the calcarine sulcus and the posterior part of the collateral sulcus; behind, it reaches the occipital pole; in front, it is continued on to the tentorial surface of the temporal lobe, and joins the hippocampal gyrus. The lingual gyrus is so-named because it resembles the tongue in shape. This region is believed to play an important role in dreaming and vision, especially in recognizing words, regardless of size, font, etc. Shunt [WP,unvetted]." [Wikipedia:Lingual_gyrus] subset: uberon_slim synonym: "lingula of cerebral hemisphere" EXACT [FMA:61904] synonym: "medial occipitotemporal gyrus" EXACT [FMA:61904] synonym: "medial occipitotemporal gyrus-2" EXACT [FMA:61904] xref: FMA:61904 ! Lingual gyrus xref: NIF_GrossAnatomy:birnlex_740 ! Lingual gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a1/Gray727_lingual_gyrus.png/200px-Gray727_lingual_gyrus.png is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002021 ! occipital lobe synonym: "gyrus occipitotemporalis medialis" EXACT LATIN [FMA:TA, FMA:61904] xref: SCTID:279203007 ! Entire medial occipitotemporal gyrus synonym: "gyrus lingualis" RELATED LATIN [Wikipedia:Lingual_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray727_lingual_gyrus.png [Term] id: UBERON:0007703 ! spinothalamic tract name: spinothalamic tract def: "a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling[GO]." [Wikipedia:Spinothalamic_tract] is_a: UBERON:0007702 ! tract of brain xref: SCTID:280417000 ! Spinothalamic tract xref: NIF_GrossAnatomy:nlx_anat_1010017 ! Spinothalamic tract xref: http://upload.wikimedia.org/wikipedia/commons/b/b2/Spinal_cord_tracts_-_English.svg [Term] id: UBERON:0002609 name: spinothalamic tract of midbrain xref: FMA:72463 ! Spinothalamic tract of midbrain xref: NIF_GrossAnatomy:birnlex_1150 ! Spinothalamic tract of midbrain is_a: UBERON:0007702 {source="FMA"} ! tract of brain relationship: part_of UBERON:0001943 ! midbrain tegmentum relationship: part_of UBERON:0007703 ! spinothalamic tract xref: SCTID:369090006 ! Entire spinothalamic tract of midbrain [Term] id: UBERON:0002798 name: spinothalamic tract of pons def: "Part of spinothalamic tract that is in the pontine tegmentum" [NIF_GrossAnatomy:birnlex_1719] synonym: "pons of varolius spinothalamic tract" EXACT [OBOL:automatic] synonym: "pons of varolius spinothalamic tract of medulla" EXACT [OBOL:automatic] synonym: "pons spinothalamic tract" EXACT [OBOL:automatic] synonym: "pons spinothalamic tract of medulla" EXACT [OBOL:automatic] synonym: "spinothalamic tract of medulla of pons" EXACT [OBOL:automatic] synonym: "spinothalamic tract of medulla of pons of varolius" EXACT [OBOL:automatic] synonym: "spinothalamic tract of pons of varolius" EXACT [OBOL:automatic] xref: FMA:72504 ! Spinothalamic tract of pons xref: NIF_GrossAnatomy:birnlex_1719 ! Spinothalamic tract of pons is_a: UBERON:0007702 {source="FMA"} ! tract of brain relationship: part_of UBERON:0003023 {source="FMA"} ! pontine tegmentum relationship: part_of UBERON:0007703 ! spinothalamic tract xref: SCTID:369026006 ! Entire spinothalamic tract of pons [Term] id: UBERON:0002944 name: spinothalamic tract of medulla def: "Part of spinothalamic tract that is in the medulla" [NIF_GrossAnatomy:birnlex_741] subset: uberon_slim synonym: "spinothalamic tract" BROAD [FMA:72644, NIF_GrossAnatomy:birnlex_741] xref: FMA:72644 ! Spinothalamic tract of medulla xref: NIF_GrossAnatomy:birnlex_741 ! Spinothalamic tract of medulla xref: GAID:703 ! spinothalamic tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Medulla_spinalis_-_tracts_-_English.svg/200px-Medulla_spinalis_-_tracts_-_English.svg.png xref: MESH:A08.186.854.761 ! spinothalamic tract is_a: UBERON:0007702 {source="FMA"} ! tract of brain relationship: part_of UBERON:0001896 {source="FMA"} ! medulla oblongata relationship: has_function_in GO:0019233 {source="GO"} ! nociception relationship: part_of UBERON:0007703 ! spinothalamic tract xref: SCTID:360570003 ! Spinothalamic tract of medulla [Term] id: UBERON:0002945 name: ventral posteromedial nucleus def: "The ventral posteromedial nucleus is a nucleus of the thalamus. [WP,unvetted]." [Wikipedia:Ventral_posteromedial_nucleus] subset: uberon_slim synonym: "arcuate nucleus of thalamus" EXACT [FMA:62202] synonym: "arcuate nucleus-3" EXACT [FMA:62202] synonym: "posteromedial ventral nucleus of thalamus" EXACT [FMA:62202] synonym: "semilunar nucleus" EXACT [FMA:62202] synonym: "thalamic gustatory nucleus" EXACT [FMA:62202] synonym: "ventral posterior medial nucleus" EXACT [FMA:62202] synonym: "ventral posteromedial nucleus of thalamus" EXACT [FMA:62202] synonym: "arcuate nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "nucleus arcuatus thalami" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "nucleus semilunaris thalami" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "nucleus ventralis posterior medialis thalami" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "nucleus ventralis posteromedialis" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "nucleus ventralis posteromedialis thalami" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "nucleus ventrocaudalis anterior internus (hassler)" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "posteromedial ventral nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "ventral posterior medial nucleus of thalamus" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "ventral posteromedial nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "ventral posteromedial thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_743] synonym: "ventroposteromedial nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_743] xref: FMA:62202 ! Ventral posteromedial nucleus xref: NIF_GrossAnatomy:birnlex_743 ! Ventral posteromedial nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1b/ThalamicNuclei.png/200px-ThalamicNuclei.png xref: ABA:VPM ! Ventral posteromedial nucleus of the thalamus xref: BM:Die-Th-VPM ! ventral posterior medial nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0007692 {source="FMA"} ! nucleus of thalamus relationship: part_of UBERON:0002596 {source="FMA"} ! ventral posterior nucleus relationship: spatially_disjoint_from UBERON:0002942 {source="ABA"} ! ventral posterolateral nucleus xref: SCTID:369172008 ! Entire ventral posteromedial nucleus of thalamus synonym: "nucleus ventralis posteromedialis thalami" RELATED LATIN [Wikipedia:Ventral_posteromedial_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/ThalamicNuclei.png [Term] id: UBERON:0002946 name: regional part of cerebellum subset: non_informative def: "A regional part of brain that is part of a cerebellum [Automatically generated definition]." [OBOL:automatic] synonym: "segment of cerebellum" EXACT [NIF_GrossAnatomy:birnlex_748] xref: FMA:256150 ! Segment of cerebellum xref: NIF_GrossAnatomy:birnlex_748 ! Regional part of cerebellum intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002037 ! cerebellum xref: SCTID:119242005 ! Cerebellar part [Term] id: UBERON:0002948 name: superior occipital gyrus synonym: "gyrus occipitalis primus" EXACT [FMA:61901] xref: FMA:61901 ! Superior occipital gyrus xref: NIF_GrossAnatomy:birnlex_758 ! Superior occipital gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0002021 ! occipital lobe xref: SCTID:279182006 ! Entire superior occipital gyrus [Term] id: UBERON:0002949 name: tectospinal tract def: "a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord[GO]." [Wikipedia:Tectospinal_tract] subset: uberon_slim synonym: "held's bundle" EXACT [FMA:72620] synonym: "tectospinal pathway" EXACT [FMA:72620] xref: FMA:72620 ! Tectospinal tract xref: NIF_GrossAnatomy:birnlex_759 ! Tectospinal tract xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/be/Gray670.png/200px-Gray670.png xref: BM:TSp ! tectospinal tract is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001896 ! medulla oblongata synonym: "tractus tectospinalis" RELATED LATIN [Wikipedia:Tectospinal_tract] xref: http://upload.wikimedia.org/wikipedia/commons/b/be/Gray670.png [Term] id: UBERON:0002950 name: regional part of midbrain subset: non_informative def: "A regional part of brain that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "midbrain segment" EXACT [FMA:61997] synonym: "segment of midbrain" EXACT [NIF_GrossAnatomy:birnlex_763] xref: FMA:61997 ! Segment of midbrain xref: NIF_GrossAnatomy:birnlex_763 ! Regional part of midbrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001891 ! midbrain xref: SCTID:119239004 ! Midbrain part [Term] id: UBERON:0002951 name: regional part of intermediate hypothalamic region subset: non_informative def: "A regional part of brain that is part of a intermediate hypothalamic region [Automatically generated definition]." [OBOL:automatic] synonym: "intermediate hypothalamic region segment" EXACT [FMA:62310] synonym: "segment of intermediate hypothalamic region" EXACT [NIF_GrossAnatomy:birnlex_767] xref: FMA:62310 ! Segment of intermediate hypothalamic region xref: NIF_GrossAnatomy:birnlex_767 ! Regional part of intermediate hypothalamic region is_a: UBERON:0003048 ! regional part of hypothalamus intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002555 ! intermediate hypothalamic region [Term] id: UBERON:0002952 name: intermediate acoustic stria synonym: "commissure of held" EXACT [] synonym: "intermediate acoustic stria of held" EXACT [] synonym: "intermediate acoustic stria (held)" EXACT [NIF_GrossAnatomy:birnlex_768] xref: FMA:72497 ! Intermediate acoustic stria xref: NIF_GrossAnatomy:birnlex_768 ! Intermediate acoustic stria is_a: UBERON:0002316 ! white matter of neuraxis [Term] id: UBERON:0002953 name: lateral lemniscus alt_id: UBERON:0003042 def: "The lateral lemniscus is a tract of axons in the brainstem that carries information about sound from the cochlear nucleus to various brainstem nuclei and ultimately the contralateral inferior colliculus of the midbrain. Three distinct, primarily inhibitory, cellular groups are located interspersed within these fibers, and are thus named the nuclei of the lateral lemniscus. [WP,unvetted]." [Wikipedia:Lateral_lemniscus] subset: uberon_slim synonym: "lateral fillet" EXACT [FMA:72502] xref: FMA:72502 ! Lateral lemniscus xref: NIF_GrossAnatomy:birnlex_976 ! Lateral lemniscus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/44/Lateral_lemniscus.PNG/200px-Lateral_lemniscus.PNG xref: BM:Pons-LL ! lateral lemniscus is_a: UBERON:0002316 ! white matter of neuraxis is_a: UBERON:0003001 ! lemniscus xref: SCTID:362399003 ! Entire lateral lemniscus synonym: "lemniscus lateralis" RELATED LATIN [Wikipedia:Lateral_lemniscus] xref: http://upload.wikimedia.org/wikipedia/commons/4/44/Lateral_lemniscus.PNG [Term] id: UBERON:0002954 name: dorsal hypothalamic area xref: FMA:62339 ! Dorsal hypothalamic area xref: NIF_GrossAnatomy:birnlex_777 ! Dorsal hypothalamic area xref: BM:Die-Hy-HDA ! dorsal hypothalamic area is_a: UBERON:0000477 ! anatomical cluster [Term] id: UBERON:0002955 name: rhomboidal nucleus synonym: "rhomboid nucleus" EXACT [FMA:62154] synonym: "rhomboid thalamic nucleus" EXACT [FMA:62154] synonym: "nucleus commissuralis rhomboidalis" RELATED [BTO:0002458] synonym: "nucleus rhomboidalis" RELATED [BTO:0002458] xref: FMA:62154 ! Rhomboidal nucleus xref: NIF_GrossAnatomy:birnlex_778 ! Rhomboidal nucleus xref: BTO:0002458 ! rhomboid nucleus xref: ABA:RH ! Rhomboid nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0003036 {source="ABA"} ! central lateral nucleus relationship: spatially_disjoint_from UBERON:0001923 {source="ABA"} ! central medial nucleus relationship: spatially_disjoint_from UBERON:0001924 {source="ABA"} ! paracentral nucleus relationship: spatially_disjoint_from UBERON:0001922 {source="ABA"} ! parafascicular nucleus [Term] id: UBERON:0004130 ! cerebellar layer name: cerebellar layer synonym: "cell layer of cerebellar cortex" EXACT [] synonym: "layer of cerebellar cortex" EXACT [] synonym: "gray matter layer of cerebellum" EXACT [FMA:83141] xref: MA:0000201 ! cerebellar layer xref: FMA:83141 ! gray matter layer of cerebellum [subclass: "gray matter layer of neuraxis"] is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002129 ! cerebellar cortex xref: SCTID:360478008 ! Layer of cerebellum xref: ncithesaurus:Cortical_Cell_Layer_of_the_Cerebellum ! Cortical Cell Layer of the Cerebellum xref: UMLS:C1707522 [Term] id: UBERON:0002956 name: granular layer of cerebellar cortex def: "The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer." [GO:0021681] synonym: "cerebellar granular layer" EXACT [GO:0021681] synonym: "cerebellar granule cell layer" EXACT [] synonym: "cerebellum granule cell layer" EXACT [MA:0000993] synonym: "cerebellum granule layer" EXACT [] synonym: "cerebellar granule layer" EXACT [] synonym: "granule cell layer of cerebellar cortex" EXACT [NIF_GrossAnatomy:birnlex_779] xref: MA:0000993 ! cerebellum granule cell layer xref: FMA:83140 ! Granular layer of cerebellar cortex xref: NIF_GrossAnatomy:birnlex_779 ! Granular layer of cerebellar cortex xref: BTO:0004425 ! stratum granulosum cerebelli xref: ABA:CBXgr ! Cerebellar cortex, granular layer xref: ncithesaurus:Granular_Layer_of_the_Cerebellum ! Granular Layer of the Cerebellum is_a: UBERON:0004130 ! cerebellar layer relationship: part_of UBERON:0002129 ! cerebellar cortex relationship: spatially_disjoint_from UBERON:0002979 {source="ABA"} ! Purkinje cell layer of cerebellar cortex xref: UMLS:C1708253 [Term] id: UBERON:0002957 name: caudal central oculomotor nucleus synonym: "caudal central nucleus" EXACT [FMA:72426] synonym: "caudal central nucleus of oculomotor nerve" EXACT [FMA:72426] xref: FMA:72426 ! Caudal central oculomotor nucleus xref: NIF_GrossAnatomy:birnlex_780 ! Caudal central oculomotor nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain xref: SCTID:369239004 ! Entire oculomotor nerve central caudal nucleus [Term] id: UBERON:0002958 name: medial lemniscus of pons def: "A medial lemniscus that is part of a pons [Automatically generated definition]." [OBOL:automatic] synonym: "medial lemniscus of pons of varolius" EXACT [OBOL:automatic] synonym: "pons medial lemniscus" EXACT [OBOL:automatic] synonym: "pons of varolius medial lemniscus" EXACT [OBOL:automatic] xref: FMA:72503 ! Medial lemniscus of pons xref: NIF_GrossAnatomy:birnlex_781 ! Medial lemniscus of pons is_a: UBERON:0003002 ! medial lemniscus intersection_of: UBERON:0003002 ! medial lemniscus intersection_of: part_of UBERON:0000988 ! pons [Term] id: UBERON:0002959 name: subfascicular nucleus xref: FMA:62155 ! Subfascicular nucleus xref: NIF_GrossAnatomy:birnlex_783 ! Subfascicular nucleus is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002960 name: central oculomotor nucleus synonym: "central nucleus of perlia" EXACT [] synonym: "nucleus of perlia" EXACT [] synonym: "spitzka's nucleus" EXACT [FMA:72425] xref: FMA:72425 ! Central oculomotor nucleus xref: NIF_GrossAnatomy:birnlex_786 ! Central oculomotor nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002961 name: archicortex def: "A portion of the cerebral cortex that, with the paleocortex, develops in association with the olfactory system, and which is phylogenetically older than the neocortex and lacks its layered structure. The embryonic archicortex corresponds to the cortex of the dentate gyrus and hippocampus in mature mammals. Being part of the limbic system, it has functions related to emotions and formation of memory. Signals being sent from the limbic lobe to the hippocampal formations can go via the archicortex as an intermediate." [Wikipedia:Archicortex] subset: uberon_slim synonym: "archipallium" EXACT [FMA:62424] xref: FMA:62424 ! Archicortex xref: NIF_GrossAnatomy:birnlex_787 is_a: UBERON:0002619 ! region of cerebral cortex xref: SCTID:423918008 ! Structure of archicortex xref: EHDAA2:0004496 ! archipallium [Term] id: UBERON:0002963 name: caudal pontine reticular nucleus def: "The caudal pontine reticular nucleus is composed of gigantocellular neurons. In rabbits and cats it is exclusively giant cells, however in humans there are normally sized cells as well. The pontis caudalis is rostral to the gigantocellular nucleus and is located in the caudal pons, as the name would indicate. The pontis caudalis has been known to mediate head movement, in concert with the nucleus gigantocellularis and the superior colliculus. The neurons in the dorsal half of this nuclei fire rhythmically during mastication, and in an anesthetized animal it is possible to induce mastication via electrical stimulation of the PC or adjacent areas of the gigantocellular nucleus. The pontis caudalis is also thought to play a role in the grinding of teeth during sleep. [WP,unvetted]." [Wikipedia:Caudal_pontine_reticular_nucleus] subset: uberon_slim synonym: "pontine reticular nucleus, caudal part" EXACT [FMA:72469] xref: FMA:72469 ! Caudal pontine reticular nucleus xref: NIF_GrossAnatomy:birnlex_792 ! Caudal pontine reticular nucleus xref: ABA:PRNc ! Pontine reticular nucleus, caudal part is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0007413 {source="FMA"} ! nucleus of pontine reticular formation relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus synonym: "nucleus reticularis pontis caudalis" RELATED LATIN [Wikipedia:Caudal_pontine_reticular_nucleus] [Term] id: UBERON:0002964 name: dorsal oculomotor nucleus synonym: "dorsal oculomotor cell column" EXACT [FMA:62442] xref: FMA:62442 ! Dorsal oculomotor nucleus xref: NIF_GrossAnatomy:birnlex_793 ! Dorsal oculomotor nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002965 name: rostral intralaminar nuclei synonym: "rostral intralaminar nuclei" EXACT [FMA:62164] synonym: "rostral intralaminar nuclear group" EXACT [FMA:62164] synonym: "nuclei intralaminares rostrales" EXACT [NIF_GrossAnatomy:birnlex_794] xref: FMA:62164 ! Rostral intralaminar nuclear group xref: NIF_GrossAnatomy:birnlex_794 ! Rostral intralaminar nuclei is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002966 name: regional part of midbrain tectum subset: non_informative def: "A regional part of brain that is part of a midbrain tectum [Automatically generated definition]." [OBOL:automatic] synonym: "midbrain tectum segment" EXACT [FMA:62398] synonym: "segment of midbrain tectum" EXACT [NIF_GrossAnatomy:birnlex_795] xref: FMA:62398 ! Segment of midbrain tectum xref: NIF_GrossAnatomy:birnlex_795 ! Regional part of midbrain tectum intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002314 ! midbrain tectum [Term] id: UBERON:0002967 ! cingulate gyrus name: cingulate gyrus def: "A gyrus in the medial part of the brain. It partially wraps around the corpus callosum and is limited above by the cingulate sulcus. The cortical part of the cingulate gyrus is referred to as cingulate cortex.[Wikipedia]. The cingulate gyrus receives inputs from the anterior nucleus of the thalamus and the neocortex, as well as from somatosensory areas of the cerebral cortex. It projects to the entorhinal cortex via the cingulum. It functions as an integral part of the limbic system, which is involved with emotion formation and processing, learning, and memory. Also, executive control needed to suppress inappropriate unconscious priming is known to involve the anterior cingulate gyrus. It is also involved in respiratory control." [Wikipedia:Cingulate_gyrus] subset: uberon_slim synonym: "cingulate area" EXACT [FMA:62434] synonym: "cingulate region" EXACT [FMA:62434] synonym: "falciform lobe" EXACT [FMA:62434] synonym: "upper limbic gyrus" EXACT [FMA:62434] xref: FMA:62434 ! Cingulate gyrus xref: NIF_GrossAnatomy:birnlex_798 ! Cingulate gyrus xref: BTO:0003976 ! cingulate gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Gray727_cingulate_gyrus.png/200px-Gray727_cingulate_gyrus.png xref: BM:Tel-CG ! cingulate gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0000349 ! limbic system xref: SCTID:279208003 ! Entire cingulate gyrus xref: ncithesaurus:Cingulate_Gyrus ! cingulate gyrus xref: UMLS:C0018427 [Term] id: UBERON:0002969 name: inferior temporal sulcus synonym: "inferior temporal sulcus-1" EXACT [FMA:83784] synonym: "middle temporal sulcus (szikla)" EXACT [] synonym: "second temporal sulcus" EXACT [FMA:83784] synonym: "sulcus t2" EXACT [FMA:83784] xref: FMA:83784 ! Inferior temporal sulcus xref: NIF_GrossAnatomy:birnlex_800 ! Inferior temporal sulcus xref: ncithesaurus:Inferior_Temporal_Sulcus ! Inferior Temporal Sulcus xref: BM:Tel-Cx-ITS ! inferior temporal sulcus is_a: UBERON:0000093 ! sulcus xref: SCTID:279346007 ! Entire inferior temporal sulcus xref: UMLS:C0228242 [Term] id: UBERON:0002970 name: intermediate oculomotor nucleus synonym: "intermediate oculomotor cell column" EXACT [FMA:72420] xref: FMA:72420 ! Intermediate oculomotor nucleus xref: NIF_GrossAnatomy:birnlex_803 ! Intermediate oculomotor nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002971 name: periolivary nucleus synonym: "dorsal periolivary nucleus" EXACT [FMA:72475] synonym: "peri-olivary nuclei" EXACT [FMA:72475] xref: MA:0002757 ! periolivary nucleus xref: NIF_GrossAnatomy:birnlex_804 ! Periolivary nucleus xref: FMA:72475 ! dorsal periolivary nucleus is_a: UBERON:0002680 ! regional part of metencephalon relationship: part_of UBERON:0002128 ! superior olivary complex synonym: "nuclei periolivares" EXACT LATIN [FMA:TA, FMA:72475] [Term] id: UBERON:0002972 name: centromedian nucleus def: "In the anatomy of the brain, the centromedian nucleus, also known as the centrum medianum, (CM or Cm-Pf) is a part of the intralaminar nucleus (ILN) of the thalamus. There are two centromedian nuclei arranged bilaterally. It contains about 2000 neurons per cubic millimetre and has a volume of about 310 cubic millimetres with 664,000 neurons in total. [WP,unvetted]." [Wikipedia:Centromedian_nucleus] subset: uberon_slim synonym: "central magnocellular nucleus of thalamus" EXACT [FMA:62165] synonym: "central nucleus-1" EXACT [FMA:62165] synonym: "centre median nucleus" EXACT [FMA:62165] synonym: "centromedian nucleus of thalamus" EXACT [FMA:62165] synonym: "centromedian thalamic nucleus" EXACT [FMA:62165] synonym: "noyau centre median of luys" EXACT [] synonym: "centrum medianum" EXACT [NIF_GrossAnatomy:birnlex_805] synonym: "centrum medianum thalami" EXACT [NIF_GrossAnatomy:birnlex_805] synonym: "nucleus centralis centralis" EXACT [NIF_GrossAnatomy:birnlex_805] synonym: "nucleus centralis thalami (hassler)" EXACT [NIF_GrossAnatomy:birnlex_805] synonym: "nucleus centri mediani thalami" EXACT [NIF_GrossAnatomy:birnlex_805] synonym: "nucleus centromedianus" EXACT [NIF_GrossAnatomy:birnlex_805] synonym: "nucleus centromedianus thalami" EXACT [NIF_GrossAnatomy:birnlex_805] synonym: "nucleus centrum medianum" EXACT [NIF_GrossAnatomy:birnlex_805] xref: FMA:62165 ! Centromedian nucleus xref: NIF_GrossAnatomy:birnlex_805 ! Centromedian nucleus xref: EV:0100215 ! centromedian thalamic nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002733 {source="FMA"} ! intralaminar nuclear group xref: ncithesaurus:Centromedian_Nucleus_of_the_Thalamus ! Centromedian Nucleus of the Thalamus xref: SCTID:279162007 ! Entire centromedian nucleus of thalamus synonym: "nucleus centromedianus thalami" RELATED LATIN [Wikipedia:Centromedian_nucleus] xref: UMLS:C0920328 [Term] id: UBERON:0002973 name: parahippocampal gyrus def: "a grey matter cortical region of the brain that surrounds the hippocampus. This region plays an important role in memory encoding and retrieval. The anterior part of the gyrus includes the perirhinal and entorhinal cortices. The term parahippocampal cortex is used to refer to an area that encompasses both the posterior portion of the parahippocampal gyrus and the medial portion of the fusiform gyrus.[Wikipedia]." [Wikipedia:Parahippocampal_gyrus] subset: uberon_slim synonym: "hippocampal gyrus" EXACT [FMA:61918] xref: FMA:61918 ! Parahippocampal gyrus xref: NIF_GrossAnatomy:birnlex_807 ! Parahippocampal gyrus xref: ncithesaurus:Parahippocampal_Gyrus ! Parahippocampal Gyrus xref: GAID:634 ! parahippocampal gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Human_brainstem_anterior_view_2_description.JPG/200px-Human_brainstem_anterior_view_2_description.JPG xref: BTO:0004380 ! parahippocampal gyrus xref: MESH:A08.186.211.577.710 ! parahippocampal gyrus xref: EV:0100181 ! parahippocampal gyrus is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0000349 ! limbic system relationship: part_of UBERON:0001871 ! temporal lobe relationship: surrounds UBERON:0001954 {source="Wikipedia"} ! hippocampus relationship: has_function_in GO:0007613 {source="Wikipedia"} ! memory xref: SCTID:279205000 ! Entire parahippocampal gyrus synonym: "gyrus parahippocampalis" RELATED LATIN [Wikipedia:Parahippocampal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Human_brainstem_anterior_view_2_description.JPG xref: UMLS:C0228249 [Term] id: UBERON:0006083 name: Perirhinal cortex synonym: "perirhinal area" EXACT [NIF_GrossAnatomy:nlx_anat_1005006] synonym: "perirhinal cortex" EXACT [NIF_GrossAnatomy:nlx_anat_1005006] xref: MA:0000912 ! perirhinal cortex xref: NIF_GrossAnatomy:nlx_anat_1005006 ! Perirhinal cortex xref: BTO:0004355 ! perirhinal cortex xref: ABA:PERI ! Perirhinal area xref: BM:Tel-Cx-PRh ! perirhinal cortex xref: EFO:0001978 ! perirhinal cortex is_a: UBERON:0002791 ! regional part of telencephalon relationship: part_of UBERON:0002022 ! insula [Term] id: UBERON:0002974 name: molecular layer of cerebellar cortex def: "The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [GO:0021679] comment: Taxon notes: Compare with ZFA:0000636 - cerebellar crest, which is also composed of parallel fibers but located in a more restricted nucleus within the cerebellum synonym: "cerebellar molecular layer" EXACT [GO:0021679] synonym: "cerebellum molecular layer" EXACT [] synonym: "cerebellum molecular cell layer" EXACT [] xref: FMA:83897 ! Molecular layer of cerebellar cortex xref: NIF_GrossAnatomy:birnlex_810 ! Molecular layer of cerebellar cortex xref: MA:0000996 ! cerebellum molecular cell layer is_a: UBERON:0004130 ! cerebellar layer relationship: part_of UBERON:0002129 ! cerebellar cortex xref: ncithesaurus:Molecular_Layer_of_the_Cerebellum ! Molecular Layer of the Cerebellum xref: SCTID:369045002 ! Entire molecular layer of cerebellar cortex xref: UMLS:C1709064 [Term] id: UBERON:0002975 name: medial oculomotor nucleus synonym: "medial oculomotor cell column" EXACT [FMA:72421] xref: FMA:72421 ! Medial oculomotor nucleus xref: NIF_GrossAnatomy:birnlex_813 ! Medial oculomotor nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002976 name: preolivary nucleus synonym: "preolivary nuclei" EXACT [FMA:72474] xref: FMA:72474 ! Preolivary nucleus xref: NIF_GrossAnatomy:birnlex_814 ! Preolivary nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002128 ! superior olivary complex [Term] id: UBERON:0002977 name: triangular septal nucleus synonym: "triangular nucleus of septum" EXACT [FMA:61880] synonym: "triangular nucleus septum (cajal)" EXACT [NIF_GrossAnatomy:birnlex_816] xref: FMA:61880 ! Triangular septal nucleus xref: NIF_GrossAnatomy:birnlex_816 ! Triangular septal nucleus xref: ABA:TRS ! Triangular nucleus of septum xref: BM:Tel-Spt-STN ! triangular septal nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0007629 {source="ABA"} ! medial septal complex synonym: "nucleus triangularis septi" EXACT LATIN [FMA:TA, FMA:61880] [Term] id: UBERON:0002978 name: oral part of ventral lateral nucleus synonym: "ventral anterior nucleus, pars densicellularis" EXACT [FMA:62193] synonym: "ventral lateral anterior nucleus" EXACT [FMA:62193] synonym: "ventral lateral nucleus, oral part" EXACT [FMA:62193] synonym: "ventral lateral thalamic nucleus, oral part" EXACT [FMA:62193] synonym: "nucleus lateralis oralis situs principalis" EXACT [NIF_GrossAnatomy:birnlex_817] synonym: "nucleus ventralis lateralis, pars oralis" EXACT [NIF_GrossAnatomy:birnlex_817] synonym: "nucleus ventrooralis externus, anterior part (van buren)" EXACT [NIF_GrossAnatomy:birnlex_817] synonym: "subnucleus rostralis" EXACT [NIF_GrossAnatomy:birnlex_817] xref: FMA:62193 ! Oral part of ventral lateral nucleus xref: NIF_GrossAnatomy:birnlex_817 ! Oral part of ventral lateral nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001925 ! ventral lateral nucleus [Term] id: UBERON:0002979 name: Purkinje cell layer of cerebellar cortex def: "The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells." [GO:0021680] synonym: "Purkinje cell layer" EXACT [FMA:83896] synonym: "cerebellar Purkinje cell layer" EXACT [FMA:83896, GO:0021694] synonym: "cerebellum Purkinje cell layer" EXACT [] synonym: "cerebellum Purkinje layer" EXACT [] xref: FMA:83896 ! Purkinje cell layer of cerebellar cortex xref: NIF_GrossAnatomy:birnlex_818 ! Purkinje cell layer of cerebellar cortex xref: MA:0000997 ! cerebellum purkinje cell layer xref: BTO:0004909 ! Purkinje layer xref: ABA:CBXpu ! Cerebellar cortex, Purkinje layer is_a: UBERON:0004130 ! cerebellar layer relationship: has_part CL:0000121 ! Purkinje cell relationship: part_of UBERON:0002129 ! cerebellar cortex relationship: spatially_disjoint_from UBERON:0002956 {source="ABA"} ! granular layer of cerebellar cortex xref: ncithesaurus:Purkinje_Cell_Layer_of_the_Cerebellum ! Purkinje Cell Layer of the Cerebellum xref: SCTID:369046001 ! Entire purkinje cell layer of cerebellar cortex xref: UMLS:C1709776 [Term] id: UBERON:0002980 name: opercular part of inferior frontal gyrus synonym: "opercular portion of inferior frontal gyrus" EXACT [FMA:61981] synonym: "posterior part of inferior frontal gyrus" EXACT [FMA:61981] synonym: "pars opercularis gyri frontalis inferioris" EXACT [NIF_GrossAnatomy:birnlex_823] xref: FMA:61981 ! Opercular part of inferior frontal gyrus xref: NIF_GrossAnatomy:birnlex_823 ! Opercular part of inferior frontal gyrus is_a: UBERON:0000064 ! organ part [Term] id: UBERON:0002981 name: pulvinar nucleus def: "The pulvinar is the caudal-most nucleus of the thalamus. The pulvinar is usually grouped as one of the lateral thalamic nuclei. [WP,unvetted]." [Wikipedia:Pulvinar_nuclei] subset: uberon_slim synonym: "pulvinar nuclei" EXACT [FMA:62178] synonym: "pulvinar" EXACT [FMA:62178] synonym: "pulvinar thalami" EXACT [NIF_GrossAnatomy:birnlex_824] xref: FMA:62178 ! Pulvinar xref: NIF_GrossAnatomy:birnlex_824 ! Pulvinar xref: GAID:662 ! pulvinar xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Gray719.png/200px-Gray719.png xref: BTO:0004352 ! pulvinar xref: MESH:A08.186.211.730.385.826.701.485.600 ! pulvinar xref: EV:0100213 ! pulvinar xref: BM:Die-Th-Pl ! pulvinar is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain synonym: "nuclei pulvinares" EXACT LATIN [FMA:TA, FMA:62178] xref: SCTID:279157006 ! Entire pulvinar xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray719.png [Term] id: UBERON:0002982 name: inferior pulvinar nucleus synonym: "nucleus pulvinaris inferior" EXACT [NIF_GrossAnatomy:birnlex_830] synonym: "nucleus pulvinaris inferior thalami" EXACT [NIF_GrossAnatomy:birnlex_830] synonym: "nucleus pulvinaris thalami, pars inferior" EXACT [NIF_GrossAnatomy:birnlex_830] xref: FMA:62183 ! Inferior pulvinar nucleus xref: NIF_GrossAnatomy:birnlex_830 ! Inferior pulvinar nucleus xref: BM:Die-Th-Pl-Pli ! inferior nucleus of pulvinar is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002983 name: lateral posterior nucleus synonym: "lateral posterior nucleus of thalamus" EXACT [FMA:62177] synonym: "lateral posterior thalamic nucleus" EXACT [FMA:62177] synonym: "laterodorsal nucleus, caudal part" EXACT [FMA:62177] synonym: "posterior lateral nucleus of thalamus" EXACT [FMA:62177] synonym: "lateral posterior nucleus of the thalamus" EXACT [NIF_GrossAnatomy:birnlex_835] synonym: "nucleus dorso-caudalis" EXACT [NIF_GrossAnatomy:birnlex_835] synonym: "nucleus dorsocaudalis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_835] synonym: "nucleus lateralis posterior" EXACT [NIF_GrossAnatomy:birnlex_835] synonym: "nucleus lateralis posterior thalami" EXACT [NIF_GrossAnatomy:birnlex_835] synonym: "nucleus lateralis thalami posterior" EXACT [NIF_GrossAnatomy:birnlex_835] xref: FMA:62177 ! Lateral posterior nucleus xref: NIF_GrossAnatomy:birnlex_835 ! Lateral posterior nucleus xref: BTO:0004351 ! lateral posterior nucleus xref: EV:0100212 ! lateral posterior thalamic nucleus xref: ABA:LP ! Lateral posterior nucleus of the thalamus xref: BM:Die-Th-LP ! lateral posterior nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002709 {source="ABA"} ! posterior nuclear complex relationship: spatially_disjoint_from UBERON:0003033 {source="ABA"} ! suprageniculate nucleus xref: ncithesaurus:Lateral_Posterior_Nucleus_of_the_Thalamus ! Lateral Posterior Nucleus of the Thalamus xref: SCTID:279155003 ! Entire lateral posterior nucleus of thalamus xref: UMLS:C0228341 [Term] id: UBERON:0002984 name: lateral dorsal nucleus synonym: "lateral dorsal nucleus of thalamus" EXACT [FMA:62176] synonym: "lateral dorsal thalamic nucleus" EXACT [FMA:62176] synonym: "laterodorsal nucleus, superficial part" EXACT [FMA:62176] synonym: "laterodorsal thalamic nucleus" EXACT [FMA:62176] synonym: "laterodorsal nucleus nucleus of thalamus" EXACT [NIF_GrossAnatomy:birnlex_838] synonym: "laterodorsal nucleus thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_838] synonym: "nucleus dorsalis superficialis (hassler)" EXACT [NIF_GrossAnatomy:birnlex_838] synonym: "nucleus dorsolateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_838] synonym: "nucleus lateralis dorsalis" EXACT [NIF_GrossAnatomy:birnlex_838] synonym: "nucleus lateralis dorsalis of thalamus" EXACT [NIF_GrossAnatomy:birnlex_838] synonym: "nucleus lateralis dorsalis thalami" EXACT [NIF_GrossAnatomy:birnlex_838] synonym: "nucleus lateralis thalami dorsalis" EXACT [NIF_GrossAnatomy:birnlex_838] xref: FMA:62176 ! Lateral dorsal nucleus xref: NIF_GrossAnatomy:birnlex_838 ! Lateral dorsal nucleus xref: BTO:0004349 ! laterodorsal thalamic nucleus xref: BTO:0004350 ! lateral dorsal nucleus xref: EV:0100211 ! lateral dorsal thalamic nucleus xref: ABA:LD ! Lateral dorsal nucleus of thalamus xref: BM:Die-Th-LD ! lateral dorsal nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002679 {source="ABA"} ! anterodorsal nucleus relationship: spatially_disjoint_from UBERON:0002681 {source="ABA"} ! anteromedial nucleus relationship: spatially_disjoint_from UBERON:0002685 {source="ABA"} ! anteroventral nucleus synonym: "nucleus dorsalis lateralis thalami" EXACT LATIN [FMA:TA, FMA:62176] xref: SCTID:279154004 ! Entire lateral dorsal nucleus of thalamus [Term] id: UBERON:0002985 name: ventral nucleus of medial geniculate body synonym: "medial geniculate complex, ventral part" EXACT [FMA:62217] synonym: "medial geniculate nucleus, ventral part" EXACT [FMA:62217] synonym: "ventral nucleus of medial geniculate complex" EXACT [FMA:62217] synonym: "ventral principal nucleus of medial geniculate body" EXACT [FMA:62217] synonym: "medial nucleus of medial geniculate complex" EXACT [NIF_GrossAnatomy:birnlex_845] synonym: "nucleus corporis geniculati medialis, pars ventralis" EXACT [NIF_GrossAnatomy:birnlex_845] synonym: "nucleus geniculatus medialis fasciculosus (hassler)" EXACT [NIF_GrossAnatomy:birnlex_845] synonym: "nucleus geniculatus medialis pars ventralis" EXACT [NIF_GrossAnatomy:birnlex_845] xref: FMA:62217 ! Ventral nucleus of medial geniculate body xref: NIF_GrossAnatomy:birnlex_845 ! Ventral nucleus of medial geniculate body xref: BTO:0002671 ! ventral principal nucleus of medial geniculate body xref: ABA:MGv ! Medial geniculate complex, ventral part xref: BM:Die-Th-MG-MGv ! ventral nucleus of medial geniculate complex is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0001927 ! medial geniculate body relationship: spatially_disjoint_from UBERON:0002758 {source="ABA"} ! dorsal nucleus of medial geniculate body relationship: spatially_disjoint_from UBERON:0002759 {source="ABA"} ! magnocellular nucleus of medial geniculate body synonym: "nucleus ventralis corporis geniculati medialis" EXACT LATIN [FMA:TA, FMA:62217] [Term] id: UBERON:0002986 name: neurofilament def: "." [Wikipedia:Neurofilament] subset: uberon_slim synonym: "neuronal intermediate filament" EXACT [FMA:63859] xref: FMA:63859 ! Neurofilament xref: NIF_GrossAnatomy:birnlex_846 xref: ncithesaurus:Neurofilament ! Neurofilament xref: GO:0005883 ! neurofilament xref: NIF_Subcellular:sao1316272517 ! Neurofilament is_a: UBERON:0003000 ! intermediate filament xref: UMLS:C0027834 [Term] id: UBERON:0002991 name: supramammillary commissure synonym: "commissure of forel" EXACT [] synonym: "commissure y" EXACT [FMA:62056] synonym: "postmammillary decussation" EXACT [FMA:62056] synonym: "supramammillary decussation" EXACT [FMA:62056] xref: FMA:62056 ! Supramammillary commissure xref: NIF_GrossAnatomy:birnlex_859 ! Supramammillary commissure is_a: UBERON:0011590 {source="FMA"} ! commissure of diencephalon relationship: part_of UBERON:0002770 {source="FMA"} ! posterior hypothalamic region xref: SCTID:369148003 ! Entire supramammillary decussation [Term] id: UBERON:0002992 name: paratenial nucleus def: "One of the median nuclei of the thalamus, situated ventral and medial to the stria medullaris." [BTO:0002457] synonym: "nucleus parataenialis thalami" RELATED [BTO:0002457] synonym: "paratenial nucleus of thalamus" RELATED [BTO:0002457] synonym: "nucleus parataenialis" EXACT [BTO:0002457] synonym: "parataenial nucleus" EXACT [FMA:62151] synonym: "paratenial thalamic nucleus" EXACT [FMA:62151] xref: BTO:0002457 ! nucleus parataenialis xref: FMA:62151 ! Paratenial nucleus xref: NIF_GrossAnatomy:birnlex_860 ! Paratenial nucleus xref: ABA:PT ! Parataenial nucleus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002705 {source="FMA", source="NIF", source="ABA"} ! midline nuclear group relationship: spatially_disjoint_from UBERON:0001920 {source="ABA"} ! paraventricular nucleus of thalamus synonym: "nucleus parataenialis" EXACT LATIN [FMA:TA, FMA:62151] xref: SCTID:422800004 ! Entire paratenial nucleus of thalamus [Term] id: UBERON:0002994 name: nucleus of pretectal area synonym: "pretectal area nucleus" EXACT [FMA:72401] xref: FMA:72401 ! Nucleus of pretectal area xref: NIF_GrossAnatomy:birnlex_864 ! Nucleus of pretectal area is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001944 ! pretectal region [Term] id: UBERON:0002995 name: substantia nigra pars lateralis def: "Regional part of substantia nigra consisting of loosely packed cells, generally located ventral and lateral to the pars compacta. Many cells in this region use GABA as a neurotransmitter (MM)." [NIF_GrossAnatomy:birnlex_866] comment: disjointness violation - relationship: part_of UBERON:0001966 {source="NIF"} ! substantia nigra pars reticulata synonym: "pars lateralis" EXACT [NIF_GrossAnatomy:birnlex_866] synonym: "lateral part of substantia nigra" EXACT [FMA:76844] synonym: "Substantia nigra, lateral part" EXACT [ABA:SNI] xref: MA:0001065 ! substantia nigra pars lateralis xref: FMA:76844 ! lateral part of substantia nigra xref: NIF_GrossAnatomy:birnlex_866 ! Substantia nigra pars lateralis xref: ABA:SNI ! Substantia nigra, lateral part is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002038 {source="MA"} ! substantia nigra relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0003040 {source="ABA"} ! central gray substance of midbrain relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus [Term] id: UBERON:0002996 name: nucleus of optic tract synonym: "large-celled nucleus of optic tract" EXACT [FMA:72403] synonym: "lentiform nucleus of pretectal area" EXACT [FMA:72403] synonym: "optic tract nucleus" EXACT [FMA:72403] synonym: "nucleus of the optic tract" EXACT [NIF_GrossAnatomy:birnlex_868] xref: FMA:72403 ! Nucleus of optic tract xref: NIF_GrossAnatomy:birnlex_868 ! Nucleus of optic tract xref: ABA:NOT ! Nucleus of the optic tract is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum relationship: part_of UBERON:0001944 ! pretectal region relationship: spatially_disjoint_from UBERON:0002711 {source="ABA"} ! nucleus of posterior commissure relationship: spatially_disjoint_from UBERON:0002565 {source="ABA"} ! olivary pretectal nucleus relationship: spatially_disjoint_from UBERON:0006848 {source="ABA"} ! posterior pretectal nucleus [Term] id: UBERON:0002997 name: nucleus of medial eminence synonym: "medial eminence nucleus" EXACT [FMA:72467] synonym: "nucleus of eminentia teres" EXACT [FMA:72467] xref: FMA:72467 ! Nucleus of medial eminence xref: NIF_GrossAnatomy:birnlex_870 ! Nucleus of medial eminence is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0002998 name: inferior frontal gyrus def: "The inferior frontal gyrus is a gyrus of the frontal lobe of the human brain. Its superior border is the inferior frontal sulcus, its inferior border the lateral fissure, and its posterior border is the inferior precentral sulcus. Above it is the middle frontal gyrus, behind it the precentral gyrus. [WP,unvetted]." [Wikipedia:Inferior_frontal_gyrus] comment: ncit has two classes, but these are exact synonyms in FMA subset: uberon_slim synonym: "inferior frontal convolution" EXACT [FMA:61860] xref: FMA:61860 ! Inferior frontal gyrus xref: ncithesaurus:Inferior_Frontal_Convolution ! Inferior Frontal Convolution xref: ncithesaurus:Inferior_Frontal_Gyrus ! Inferior Frontal Gyrus xref: NIF_GrossAnatomy:birnlex_873 ! Inferior frontal gyrus xref: BTO:0004835 ! inferior frontal gyrus is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001870 ! frontal lobe xref: SCTID:362333004 ! Entire inferior frontal gyrus synonym: "gyrus frontalis inferior" RELATED LATIN [Wikipedia:Inferior_frontal_gyrus] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Inferior_frontal_gyrus.png xref: UMLS:C0152298 [Term] id: UBERON:0002999 name: oral pontine reticular nucleus def: "The oral pontine reticular nucleus is delineated from its caudal brother, with which it shares its first three names. This nucleus tapers into the lower mesencephalic reticular formation and contains sporadic giant cells. Different populations of the pontis oralis have displayed discharge patterns which coordinate with phasic movements to and from paradoxical sleep. From this information it has been implied that the n.r. pontis oralis is involved in the mediation of changing to and from REM sleep. [WP,unvetted]." [Wikipedia:Oral_pontine_reticular_nucleus] subset: uberon_slim synonym: "pontine reticular nucleus, rostral part" EXACT [FMA:72468] xref: FMA:72468 ! Oral pontine reticular nucleus xref: NIF_GrossAnatomy:birnlex_875 ! Oral pontine reticular nucleus xref: ABA:PRNv ! Pontine reticular nucleus, ventral part is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0007413 {source="FMA"} ! nucleus of pontine reticular formation relationship: part_of UBERON:0003023 {source="FMA"} ! pontine tegmentum synonym: "nucleus reticularis pontis oralis" RELATED LATIN [Wikipedia:Oral_pontine_reticular_nucleus] [Term] id: UBERON:0003000 name: intermediate filament def: "." [Wikipedia:Intermediate_filament] subset: uberon_slim xref: FMA:63851 ! Intermediate filament xref: NIF_GrossAnatomy:birnlex_879 xref: ncithesaurus:Intermediate_Filament ! Intermediate Filament xref: GO:0005882 ! intermediate filament xref: GAID:1079 ! intermediate filament xref: NIF_Subcellular:sao952483289 ! Intermediate Filament xref: MESH:A11.284.195.190.750.410 ! intermediate filament is_a: UBERON:0000470 ! cell part xref: UMLS:C0021770 [Term] id: UBERON:0003001 ! lemniscus name: lemniscus def: "A bundle or band of sensory nerve fibers. ribbon, from Greek lemniskos." [Wikipedia:Lemniscus_(anatomy), NIF_GrossAnatomy:birnlex_881] subset: uberon_slim xref: FMA:76742 ! Lemniscus xref: NIF_GrossAnatomy:birnlex_881 ! Lemniscus is_a: UBERON:0002616 ! regional part of brain [Term] id: UBERON:0003002 name: medial lemniscus def: "The medial lemniscus, also known as Reil's band or Reil's ribbon, is a pathway in the brainstem that carries sensory information from the gracile and cuneate nuclei to the thalamus. [WP,unvetted]." [Wikipedia:Medial_lemniscus] subset: uberon_slim xref: FMA:83675 ! Medial lemniscus xref: NIF_GrossAnatomy:birnlex_887 ! Medial lemniscus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray759.png/200px-Gray759.png xref: BM:LM ! medial lemniscus is_a: UBERON:0002316 ! white matter of neuraxis is_a: UBERON:0003001 ! lemniscus xref: SCTID:362398006 ! Entire medial lemniscus synonym: "lemniscus medialis" RELATED LATIN [Wikipedia:Medial_lemniscus] xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Gray759.png [Term] id: UBERON:0003003 name: microfilament def: "." [Wikipedia:Microfilament] subset: uberon_slim synonym: "microfilament" EXACT [FMA:63850] synonym: "microfilamentum" EXACT [FMA:63850] synonym: "actin filament" EXACT [FMA:63850] xref: FMA:63850 ! Actin filament xref: NIF_GrossAnatomy:birnlex_888 xref: GO:0005884 ! actin filament xref: GAID:1080 ! microfilament xref: NIF_Subcellular:sao2006047981 ! Microfilament xref: MESH:A11.284.195.190.750.510 ! microfilament is_a: UBERON:0000470 ! cell part xref: ncithesaurus:Actin_Filament ! Actin Filament xref: UMLS:C0025979 [Term] id: UBERON:0007414 alt_id: UBERON:0012277 ! tegmental nucleus name: nucleus of midbrain tegmentum def: "A nucleus of brain that is part of a midbrain tegmentum." [OBOL:automatic] comment: This class groups together any nuclei in the tegmentum region, possibly including disparate structures across species xref: FMA:258768 ! nucleus of midbrain tegmentum xref: ZFA:0005577 ! tegmental nucleus synonym: "tegmental nucleus" EXACT [ZFA:0005577] intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0004684 ! raphe nuclei name: raphe nuclei def: "Thin plates of cells in and immediately adjacent to the sagittal plane[NIF]. A moderate-size cluster of nuclei found in the brain stem. Their main function is to release serotonin to the rest of the brain. Selective serotonin reuptake inhibitor (SSRI) antidepressants are believed to act in these nuclei, as well as at their targets. The raphe nuclei are traditionally considered to be the medial portion of the reticular formation, and they appear as a ridge of cells in the center and most medial portion of the brain stem." [NIF_GrossAnatomy:nlx_anat_20090205, Wikipedia:Raphe_nuclei, https://sourceforge.net/tracker/?func=detail&aid=3248146&group_id=36855&atid=440764] comment: we treat NR obscurus, NR magnus etc as parts of the raphe nuclei. This is consistent with treatment in FMA, where the class is 'set of raphe nuclei' subset: vertebrate_core synonym: "raphe cluster" RELATED [Wikipedia:Raphe_nuclei] synonym: "raphe nuclei" EXACT [NIF_GrossAnatomy:nlx_anat_20090205] synonym: "raphe nuclei" EXACT [FMA:84017] synonym: "raphe nuclei set" EXACT [FMA:84017] synonym: "raphe nucleus" RELATED [ZFA:0001429] xref: FMA:84017 ! set of raphe nuclei xref: NIF_GrossAnatomy:nlx_anat_20090205 ! Raphe Nuclei xref: ZFA:0001429 ! raphe nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/94/Gray694.png/200px-Gray694.png xref: MESH:A08.186.211.132.659.632 ! raphe nuclei is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002275 {source="GO", source="Wikipedia"} ! reticular formation relationship: capable_of GO:0001820 {source="Wikipedia"} ! serotonin secretion synonym: "nuclei raphes" EXACT LATIN [FMA:TA, FMA:84017] xref: ncithesaurus:Raphe_Nuclei ! raphe nuclei xref: TAO:0001429 ! raphe nucleus synonym: "nuclei raphes" RELATED LATIN [Wikipedia:Raphe_nuclei] xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png synonym: "set of raphe nuclei" RELATED [FMA:84017] xref: UMLS:C0034671 [Term] id: UBERON:0007412 name: midbrain raphe nuclei def: "Midline nuclei found in the midbrain, includes the dorsal raphe nucleus and the rostral linear nucleus of raphe." [NIF_GrossAnatomy:birnlex_1676] comment: todo - check. note BTO class is placed here as it is placed in hindbrain synonym: "raphe nuclei of tegmentum of midbrain" EXACT [FMA:77787] synonym: "raphe nucleus" BROAD [BTO:0003387] synonym: "set of raphe nuclei of tegmentum of midbrain" EXACT [FMA:77787] synonym: "midbrain raphe" EXACT [NIF_GrossAnatomy:birnlex_1676] synonym: "midbrain raphe nuclei" EXACT [NIF_GrossAnatomy:birnlex_1676] xref: BTO:0003387 ! raphe nucleus xref: FMA:77787 ! set of raphe nuclei of tegmentum of midbrain xref: NIF_GrossAnatomy:birnlex_1676 ! Midbrain raphe nuclei xref: ABA:RAmb ! Midbrain raphe nuclei is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0004684 {source="Wikipedia"} ! raphe nuclei relationship: spatially_disjoint_from UBERON:0002142 {source="ABA"} ! pedunculopontine tegmental nucleus relationship: spatially_disjoint_from UBERON:0001965 {source="ABA"} ! substantia nigra pars compacta synonym: "nuclei raphes tegmenti mesencephali" EXACT LATIN [FMA:TA, FMA:77787] [Term] id: UBERON:0002692 ! medullary raphe nuclear complex name: medullary raphe nuclear complex synonym: "raphe nuclei of medulla" EXACT [FMA:68874] synonym: "raphe of medulla oblongata" EXACT [FMA:68874] xref: FMA:68874 ! Medullary raphe nuclear complex xref: NIF_GrossAnatomy:birnlex_1420 ! Medullary raphe nuclear complex is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0001896 {source="FMA"} ! medulla oblongata relationship: part_of UBERON:0004684 {source="Wikipedia"} ! raphe nuclei synonym: "raphe medullae oblongatae" EXACT LATIN [FMA:TA, FMA:68874] xref: SCTID:362420006 ! Entire raphe of medulla oblongata [Term] id: UBERON:0003004 name: median raphe nucleus def: "The median raphe nucleus (or superior central nucleus) is composed of polygonal, fusiform and pyriform neurons and exists rostral to the nucleus raphe pontis. One trait of the MRN is its inhibition by lysergic acid diethylamide and psilocin, two serotonin antagonist hallucinogens. The inactivation of the nucleus centralis superior via LSD produces a dose dependent inactivation in the MRN, but not in the raphe pallidus[WP,unvetted]." [Wikipedia:Median_raphe_nucleus, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3248146&group_id=36855] comment: TODO: The term medial raphe nucleus refers to a composite structure that consists of the superior central nucleus and the inferior central nucleus of the pontine reticular formation ( Carpenter-1983 )[http://braininfo.rprc.washington.edu/centraldirectory.aspx?type=h&ID=1391] subset: uberon_slim synonym: "cell group b8" EXACT [] synonym: "MRN" EXACT [] synonym: "medial raphe nucleus" EXACT [] synonym: "median nucleus of the raphe" EXACT [FMA:72465] synonym: "superior central nucleus" EXACT [FMA:72465] synonym: "superior central nucleus raphe" EXACT [FMA:72465] synonym: "superior central tegmental nucleus" EXACT [FMA:72465] xref: FMA:72465 ! Superior central nucleus xref: NIF_GrossAnatomy:birnlex_889 ! Superior central nucleus xref: ABA:CS ! Superior central nucleus raphe xref: BM:MR ! median raphe nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0004684 {source="Wikipedia"} ! raphe nuclei relationship: part_of UBERON:0002639 {source="Wikipedia"} ! midbrain reticular formation relationship: spatially_disjoint_from UBERON:0002148 {source="ABA"} ! locus ceruleus relationship: spatially_disjoint_from UBERON:0002267 {source="ABA"} ! laterodorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002047 {source="ABA"} ! pontine raphe nucleus relationship: spatially_disjoint_from UBERON:0002587 {source="ABA"} ! nucleus subceruleus synonym: "nucleus raphes medianus" EXACT LATIN [FMA:TA, FMA:72465] synonym: "nucleus raphes medianus, nucleus centralis superior" RELATED LATIN [Wikipedia:Median_raphe_nucleus] [Term] id: UBERON:0002043 name: dorsal raphe nucleus def: "A large raphe nucleus extending from the anterior part of the pons through the mesencephalon; its neurons are serotoninergic[NIF]. The dorsal raphe nucleus is a part of the raphe nucleus and consists of rostral and caudal subdivisions. The rostral aspect of the dorsal raphe is further divided into interfascicular, ventral, ventrolateral and dorsal subnuclei. The projections of the dorsal raphe have been found to vary topographically, and thus the subnuclei differ in their projections. An increased number of cells in the lateral aspects of the dorsal raphe is characteristic of humans and other primates. [WP,unvetted]." [Wikipedia:Dorsal_raphe_nucleus, NIF_GrossAnatomy:birnlex_982, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3248146&group_id=36855] comment: TODO check dorsal vs inferior. ZF has no pons. subset: uberon_slim subset: vertebrate_core synonym: "cell group b7" EXACT [FMA:68462] synonym: "dorsal nucleus of the raphe" EXACT [FMA:68462, BrainInfo:512] synonym: "dorsal nucleus raphe" EXACT [FMA:68462] synonym: "nucleus raphes posterior" EXACT LATIN [FMA:TA] synonym: "posterior raphe nucleus" EXACT [FMA:68462] synonym: "inferior raphe nucleus" EXACT [GO:0021724] synonym: "posterior raphe nucleus" RELATED [GO:0021724] synonym: "dorsal raphe" EXACT [NIF_GrossAnatomy:birnlex_982] synonym: "nucleus raphes dorsalis" EXACT [BTO:0002434, BrainInfo:512] synonym: "nucleus raphes posterior" RELATED [BTO:0002434] xref: FMA:68462 ! Dorsal raphe nucleus xref: NIF_GrossAnatomy:birnlex_982 ! Dorsal raphe nucleus xref: TAO:0000366 ! inferior raphe nucleus xref: ZFA:0000366 ! inferior raphe nucleus xref: MA:0002980 ! dorsal raphe nucleus xref: BTO:0002434 ! dorsal raphe nucleus xref: EFO:0001919 ! dorsal raphe nucleus xref: http://upload.wikimedia.org/wikipedia/en/thumb/c/c6/Drn.png/200px-Drn.png xref: ABA:DR ! Dorsal nucleus raphe xref: BM:MB-DR ! dorsal raphe is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0004684 {source="Wikipedia"} ! raphe nuclei relationship: part_of UBERON:0002639 {source="Wikipedia"} ! midbrain reticular formation relationship: spatially_disjoint_from UBERON:0002145 {source="ABA"} ! interpeduncular nucleus synonym: "nucleus raphe posterior, nucleus raphe dorsalis" RELATED LATIN [Wikipedia:Dorsal_raphe_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Drn.png [Term] id: UBERON:0002993 name: inferior central nucleus comment: todo - compare with UBERON:0002881 ! sublingual nucleus; also to dorsal raphe nucleus. Check if the same as ZFA 'inferior raphe nucleus'. See comments on https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3248146&group_id=36855 subset: uberon_slim synonym: "inferior central nucleus (of roller)" EXACT [FMA:72466] synonym: "inferior central nucleus of raphe" EXACT [FMA:72466] synonym: "inferior central tegmental nucleus" EXACT [FMA:72466] xref: FMA:72466 ! Inferior central nucleus xref: NIF_GrossAnatomy:birnlex_861 ! Inferior central nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0007413 {source="FMA"} ! nucleus of pontine reticular formation relationship: part_of UBERON:0002573 {source="FMA"} ! pontine reticular formation [Term] id: UBERON:0002881 ! sublingual nucleus name: sublingual nucleus def: "In the substance of the formatio reticularis are two small nuclei of gray matter. The one near the dorsal aspect of the hilus of the inferior olivary nucleus is called the Sublingual nucleus (inferior central nucleus, nucleus of Roller.) [WP,unvetted]." [Wikipedia:Sublingual_nucleus] subset: uberon_slim synonym: "inferior central nucleus" RELATED INCONSISTENT [Wikipedia:Sublingual_nucleus] synonym: "nucleus of roller" RELATED [Wikipedia:Sublingual_nucleus] synonym: "nucleus of roller" EXACT [FMA:68574] xref: FMA:68574 ! Sublingual nucleus xref: NIF_GrossAnatomy:birnlex_2657 ! Sublingual nucleus xref: ABA:NR ! Nucleus of Roller is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002160 {source="ABA"} ! nucleus prepositus synonym: "nucleus sublingualis" RELATED LATIN [Wikipedia:Sublingual_nucleus] [Term] id: UBERON:0007413 name: nucleus of pontine reticular formation synonym: "pontine reticular formation nucleus" EXACT [FMA:72245] xref: FMA:72245 ! nucleus of pontine reticular formation xref: ABA:PRNr ! Pontine reticular nucleus (also: UBERON:0002573 'pontine reticular formation') intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002573 ! pontine reticular formation def: "A nucleus of brain that is part of a pontine reticular formation." [OBOL:automatic] [Term] id: UBERON:0002047 name: pontine raphe nucleus def: "The Pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]." [Wikipedia:Pontine_raphe_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "raphe of pons" EXACT [] synonym: "raphe pontis nucleus" RELATED [] xref: FMA:68875 ! Pontine raphe nucleus xref: MA:0001022 ! pontine raphe nucleus xref: NIF_GrossAnatomy:birnlex_1110 ! Pontine raphe nucleus xref: ABA:RPO ! Nucleus raphe pontis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0003023 ! pontine tegmentum relationship: part_of UBERON:0004684 {source="Wikipedia"} ! raphe nuclei relationship: spatially_disjoint_from UBERON:0003004 {source="ABA"} ! median raphe nucleus relationship: spatially_disjoint_from UBERON:0002148 {source="ABA"} ! locus ceruleus relationship: spatially_disjoint_from UBERON:0002267 {source="ABA"} ! laterodorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002587 {source="ABA"} ! nucleus subceruleus synonym: "raphe pontis" EXACT LATIN [FMA:TA, FMA:68875] synonym: "nucleus raphes pontis" RELATED LATIN [Wikipedia:Pontine_raphe_nucleus] [Term] id: UBERON:0007635 name: nucleus of medulla oblongata xref: FMA:258772 ! nucleus of medulla oblongata intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0001896 ! medulla oblongata xref: SCTID:304943004 ! Nucleus of medulla oblongata def: "A neural nucleus that is part of a medulla oblongata." [OBOL:automatic] [Term] id: UBERON:0002156 name: nucleus raphe magnus def: "The nucleus raphe magnus, located directly rostral to the raphe obscurus, is afferently stimulated from axons in the spinal cord and cerebellum. This makes the magnus a likely candidate for part of the motor system; however, it seems to participate in the endogenous analgesia system. The magnus receives descending afferents from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, parvocellular reticular nucleus and the prelimbic, infralimbic, medial and lateral precentral cortices . All of these brain areas influence the main function of the raphe magnus. The main function of the magnus is mostly pain mediation; in fact it sends projections to the dorsal horn of the spinal cord to directly inhibit pain. The periaquiductal gray, the epicenter of analgesia, sends efferent connections to the nucleus raphe magnus in when it is stimulated by opiates (endogenous or otherwise). Electrical stimulation of the PAG produces analgesia, as well as administration of morphine to the PAG or n.r. magnus. The antinociceptic effects of electrical stimulation of the PAG can be blocked by administering naloxone, an opiate antagonist, to the n.r. magnus. All of this seems to indicate that the magnus is part of the endogenous opiate system, and acts to inhibit pain in the spinal cord. [WP,unvetted]." [Wikipedia:Nucleus_raphe_magnus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "raphe magnus" RELATED [Wikipedia:Nucleus_raphe_magnus] synonym: "raphe magnus nucleus" EXACT [NIF_GrossAnatomy:birnlex_1363] synonym: "magnus raphe nucleus" EXACT [] xref: FMA:72584 ! Nucleus raphe magnus xref: MA:0001024 ! raphe magnus nucleus xref: NIF_GrossAnatomy:birnlex_1363 ! Nucleus raphe magnus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/94/Gray694.png/200px-Gray694.png xref: ABA:RM ! Nucleus raphe magnus xref: EFO:0002518 ! raphe magnus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002692 {source="Wikipedia",source="FMA",source="NIF"} ! medullary raphe nuclear complex relationship: spatially_disjoint_from UBERON:0002684 {source="ABA"} ! nucleus raphe obscurus relationship: spatially_disjoint_from UBERON:0002157 {source="ABA"} ! nucleus raphe pallidus synonym: "nucleus raphes magnus" EXACT LATIN [FMA:TA, FMA:72584] synonym: "nucleus raphes magnus" RELATED LATIN [Wikipedia:Nucleus_raphe_magnus] xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png [Term] id: UBERON:0002157 name: nucleus raphe pallidus def: "The nucleus raphe pallidus receives afferent connections from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus. Also, the pallidus receives afferents from the medial preoptic area, median preoptic nucleus and lateral paragigantocellular reticular nuclei . The pallidus has recently been shown to be involved in the activation of a fever as an immunoreaction. It has been implied that the preoptic area is constantly inhibiting the raphe pallidus, especially the rostral portion, with GABA. When the preoptic area receives immune signals from the body, the inhibition stops and the rostral portion of the raphe pallidus excites the intermediolateral cell column, which induces a fever . The raphe pallidus has also been known to mediate the tachycardia response, an extremely high heart rate known to be incited by emotional or psychological stress. Microinjections of a GABA-a antagonist into the raphe pallidus, induces an increased heart rate. Conversely, microinjections of muscimol, a GABA-a agonist, inhibit tachycardia in rats under air-stress stimuli. In both of these cases, GABA is mediating two different sympathetic responses, so clearly the nucleus raphe pallidus is a far more a complex nucleus than previously thought. [WP,unvetted]." [Wikipedia:Nucleus_raphe_pallidus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "pallidal raphe nucleus" EXACT [] synonym: "raphe pallidus nucleus" EXACT [] xref: FMA:72586 ! Nucleus raphe pallidus xref: MA:0001051 ! raphe pallidus nucleus xref: NIF_GrossAnatomy:birnlex_1375 ! Nucleus raphe pallidus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/94/Gray694.png/200px-Gray694.png xref: ABA:RPA ! Nucleus raphe pallidus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002692 {source="FMA"} ! medullary raphe nuclear complex relationship: spatially_disjoint_from UBERON:0002156 {source="ABA"} ! nucleus raphe magnus relationship: spatially_disjoint_from UBERON:0002684 {source="ABA"} ! nucleus raphe obscurus synonym: "nucleus raphes pallidus" EXACT LATIN [FMA:TA, FMA:72586] synonym: "nucleus raphes pallidus" RELATED LATIN [Wikipedia:Nucleus_raphe_pallidus] xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png [Term] id: UBERON:0002684 name: nucleus raphe obscurus def: "The raphe obscurus projects to the cerebellar lobes VI and VII and to crus II along with the nucleus raphe pontis . This so called obscure nucleus has also been implicated in the modulation of the hypoglossal nerve. It has been observed that the ablation of this nucleus causes a change in the firing pattern in the XII nerve . In addition, the raphe obscurus mediates expiration via the inhibitory effect of serotonin and depresses periodic synaptic potentials . It has also been shown that this nucleus stimulates gastrointestinal motor function; microinjections of 5-HT into the n.r. obscurus increase gastric movement . [WP,unvetted]." [Wikipedia:Nucleus_raphe_obscurus] subset: uberon_slim synonym: "obscurus raphe nucleus" EXACT [FMA:72585] synonym: "raphe obscurus nucleus" EXACT [FMA:72585] xref: FMA:72585 ! Nucleus raphe obscurus xref: MA:0002981 ! raphe obscurus nucleus xref: NIF_GrossAnatomy:birnlex_1369 ! Nucleus raphe obscurus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/94/Gray694.png/200px-Gray694.png xref: ABA:RO ! Nucleus raphe obscurus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002692 {source="FMA"} ! medullary raphe nuclear complex relationship: spatially_disjoint_from UBERON:0002156 {source="ABA"} ! nucleus raphe magnus relationship: spatially_disjoint_from UBERON:0002157 {source="ABA"} ! nucleus raphe pallidus synonym: "nucleus raphes obscurus" EXACT LATIN [FMA:TA, FMA:72585] synonym: "nucleus raphes obscurus" RELATED LATIN [Wikipedia:Nucleus_raphe_obscurus] xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png [Term] id: UBERON:0003005 name: dorsal longitudinal fasciculus of midbrain def: "A dorsal longitudinal fasciculus that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "bundle of Schutz of midbrain" EXACT [OBOL:automatic] synonym: "fasciculus of Schutz of midbrain" EXACT [OBOL:automatic] synonym: "midbrain bundle of Schutz" EXACT [OBOL:automatic] synonym: "midbrain dorsal longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "midbrain fasciculus of Schutz" EXACT [OBOL:automatic] synonym: "midbrain posterior longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "posterior longitudinal fasciculus of midbrain" EXACT [OBOL:automatic] xref: FMA:72453 ! Dorsal longitudinal fasciculus of midbrain xref: NIF_GrossAnatomy:birnlex_893 ! Dorsal longitudinal fasciculus of midbrain is_a: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0006840 ! nucleus of lateral lemniscus name: nucleus of lateral lemniscus comment: not clear if the ZFA class denotes the same entity; check relationship to midbrain tegmentum - this leads to inconsistency with ABA. The FMA class should represnet the grouping, but there is no FMA class for the singular at the moment subset: vertebrate_core synonym: "nuclei of lateral lemniscus" RELATED [FMA:84025] synonym: "lateral lemniscus nuclei" EXACT [ZFA:0000380] xref: ZFA:0000380 ! lateral lemniscus nucleus xref: FMA:84025 ! Set of nuclei of lateral lemniscus xref: EV:0100265 ! nucleus of the lateral lemniscus xref: ABA:NLL ! Nucleus of the lateral lemniscus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0007634 {source="ABA"} ! parabrachial nucleus relationship: spatially_disjoint_from UBERON:0002597 {source="ABA"} ! principal sensory nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002128 {source="ABA"} ! superior olivary complex synonym: "nuclei lemnisci lateralis" EXACT LATIN [FMA:TA, FMA:84025] xref: SCTID:369023003 ! Entire lateral lemniscus nucleus xref: TAO:0000380 ! lateral lemniscus nucleus synonym: "set of nuclei of lateral lemniscus" RELATED [FMA:84025] synonym: "lateral lemniscus nucleus" EXACT [TAO:0000380] [Term] id: UBERON:0002604 name: ventral nucleus of lateral lemniscus def: "The lateral lemniscus is a tract of axons in the brainstem that carries information about sound from the cochlear nucleus to various brainstem nuclei and ultimately the contralateral inferior colliculus of the midbrain. Three distinct, primarily inhibitory, cellular groups are located interspersed within these fibers, and are thus named the nuclei of the lateral lemniscus. [WP,unvetted]." [Wikipedia:Ventral_nucleus_of_the_lateral_lemniscus] subset: uberon_slim synonym: "anterior nucleus of lateral lemniscus" EXACT [FMA:72484] synonym: "ventral nucleus of the lateral lemniscus" EXACT [FMA:72484] synonym: "nucleus of the lateral lemniscus, ventral part" EXACT [ABA:NLLv] xref: FMA:72484 ! Ventral nucleus of lateral lemniscus xref: NIF_GrossAnatomy:birnlex_1140 ! Ventral nucleus of lateral lemniscus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/44/Lateral_lemniscus.PNG/200px-Lateral_lemniscus.PNG xref: BM:LLV ! ventral nucleus of lateral lemniscus xref: ABA:NLLv ! nucleus of the lateral lemniscus, ventral part is_a: UBERON:0006840 ! nucleus of lateral lemniscus relationship: part_of UBERON:0003023 {source="FMA", source="NIF"} ! pontine tegmentum synonym: "nucleus anterior lemnisci lateralis" EXACT LATIN [FMA:TA, FMA:72484] [Term] id: UBERON:0003006 name: dorsal nucleus of lateral lemniscus synonym: "dorsal nucleus of the lateral lemniscus" EXACT [FMA:72483] synonym: "posterior nucleus of lateral lemniscus" EXACT [FMA:72483] synonym: "nucleus of the lateral lemniscus, dorsal part" EXACT [ABA:NLLd] xref: FMA:72483 ! Dorsal nucleus of lateral lemniscus xref: NIF_GrossAnatomy:birnlex_894 ! Dorsal nucleus of lateral lemniscus xref: BM:LLD ! dorsal nucleus of lateral lemniscus xref: ABA:NLLd ! nucleus of the lateral lemniscus, dorsal part is_a: UBERON:0006840 ! nucleus of lateral lemniscus synonym: "nucleus posterior lemnisci lateralis" EXACT LATIN [FMA:TA, FMA:72483] [Term] id: UBERON:0007710 name: intermediate nucleus of lateral lemniscus comment: todo - check synonym: "nucleus of the lateral lemniscus, horizontal part" EXACT [ABA:NLLh] xref: FMA:77485 ! intermediate nucleus of lateral lemniscus xref: ABA:NLLh ! nucleus of the lateral lemniscus, horizontal part is_a: UBERON:0006840 ! nucleus of lateral lemniscus [Term] id: UBERON:0003007 name: lateral parabrachial nucleus def: "The lateral parabrachial nucleus induces thirst by stimulating the median preoptic nucleus. It gets its name from its location relative to the superior cerebellar peduncles, which is also known as the 'brachia conjunctiva'. [WP,unvetted]." [Wikipedia:Lateral_parabrachial_nucleus] subset: uberon_slim xref: FMA:72481 ! Lateral parabrachial nucleus xref: NIF_GrossAnatomy:birnlex_897 ! Lateral parabrachial nucleus is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0003008 name: dorsal longitudinal fasciculus of hypothalamus def: "A dorsal longitudinal fasciculus that is part of a hypothalamus [Automatically generated definition]." [OBOL:automatic] synonym: "bundle of Schutz of hypothalamus" EXACT [OBOL:automatic] synonym: "bundle of Schutz of preoptico-hypothalamic area" EXACT [OBOL:automatic] synonym: "bundle of Schutz of preoptico-hypothalamic region" EXACT [OBOL:automatic] synonym: "dorsal longitudinal fasciculus of preoptico-hypothalamic area" EXACT [OBOL:automatic] synonym: "dorsal longitudinal fasciculus of preoptico-hypothalamic region" EXACT [OBOL:automatic] synonym: "fasciculus of Schutz of hypothalamus" EXACT [OBOL:automatic] synonym: "fasciculus of Schutz of preoptico-hypothalamic area" EXACT [OBOL:automatic] synonym: "fasciculus of Schutz of preoptico-hypothalamic region" EXACT [OBOL:automatic] synonym: "hypothalamus bundle of Schutz" EXACT [OBOL:automatic] synonym: "hypothalamus dorsal longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "hypothalamus fasciculus of Schutz" EXACT [OBOL:automatic] synonym: "hypothalamus posterior longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "posterior longitudinal fasciculus of hypothalamus" EXACT [OBOL:automatic] synonym: "posterior longitudinal fasciculus of preoptico-hypothalamic area" EXACT [OBOL:automatic] synonym: "posterior longitudinal fasciculus of preoptico-hypothalamic region" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic area bundle of Schutz" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic area dorsal longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic area fasciculus of Schutz" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic area posterior longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic region bundle of Schutz" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic region dorsal longitudinal fasciculus" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic region fasciculus of Schutz" EXACT [OBOL:automatic] synonym: "preoptico-hypothalamic region posterior longitudinal fasciculus" EXACT [OBOL:automatic] xref: FMA:62063 ! Dorsal longitudinal fasciculus of hypothalamus xref: NIF_GrossAnatomy:birnlex_898 ! Dorsal longitudinal fasciculus of hypothalamus is_a: UBERON:0002316 ! white matter of neuraxis is_a: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: UBERON:0003045 ! dorsal longitudinal fasciculus intersection_of: part_of UBERON:0001898 ! hypothalamus relationship: part_of UBERON:0002430 ! lateral hypothalamic area [Term] id: UBERON:0003009 name: dorsal tegmental decussation synonym: "dorsal fountain decussation" EXACT [FMA:72451] synonym: "fountain decussation of Meynert" EXACT [] synonym: "Meynert's decussation" EXACT [FMA:72451] synonym: "posterior tegmental decussation" EXACT [FMA:72451] xref: FMA:72451 ! Dorsal tegmental decussation xref: NIF_GrossAnatomy:birnlex_901 ! Dorsal tegmental decussation is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001943 ! midbrain tegmentum synonym: "decussatio tegmentalis posterior" EXACT LATIN [FMA:TA, FMA:72451] xref: SCTID:369248009 ! Entire dorsal tegmental decussation [Term] id: UBERON:0007425 name: decussation of diencephalon synonym: "diencephalon decussation" EXACT [FMA:62446] xref: FMA:62446 ! decussation of diencephalon is_a: UBERON:0007418 {source="FMA"} ! decussation of neuraxis intersection_of: UBERON:0007418 ! decussation of neuraxis intersection_of: part_of UBERON:0001894 ! diencephalon relationship: part_of UBERON:0001894 {source="Obol"} ! diencephalon def: "A decussation of neuraxis that is part of a diencephalon." [OBOL:automatic] [Term] id: UBERON:0003010 name: lateral pes lemniscus synonym: "deep pes lemniscus" EXACT [FMA:72459] synonym: "lateral pontine bundle" EXACT [FMA:72459] synonym: "laterale haubenfussschleife" EXACT [] synonym: "laterale pontine buendel" EXACT [] xref: FMA:72459 ! Lateral pes lemniscus xref: NIF_GrossAnatomy:birnlex_902 ! Lateral pes lemniscus is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0010123 name: future facial nucleus is_a: UBERON:0002020 ! gray matter of neuraxis intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: develops_into UBERON:0000127 ! facial nucleus xref: EHDAA2:0004639 ! future facial nucleus def: "A gray matter of neuraxis that develops_into a facial nucleus." [OBOL:automatic] [Term] id: UBERON:0000127 name: facial nucleus comment: FMA has 3 subclasses - left, right and motor nucleus of facial nerve, but no defs. It's not clear how facial nucleus is distinct from facial motor nucleus. synonym: "facial nerve nucleus" EXACT [] synonym: "facial VII nucleus" EXACT [MA:0001014] synonym: "facial VII motor nucleus" RELATED [MA:0001014] synonym: "nucleus of facial nerve" EXACT [FMA:54572] xref: FMA:54572 ! Facial nucleus xref: ncithesaurus:Facial_Nerve_Nucleus ! Facial Nerve Nucleus xref: VHOG:0001412 ! facial nucleus xref: MA:0001014 ! facial VII nucleus xref: EV:0100267 ! facial nucleus xref: BM:Pons-VII ! facial nucleus is_a: UBERON:0000126 ! cranial nerve nucleus relationship: part_of UBERON:0000988 ! pons xref: SCTID:280166009 ! Facial nucleus xref: EHDAA2:0004638 ! facial nucleus relationship: immediate_transformation_of UBERON:0010123 {evidence="definitional"} ! future facial nucleus xref: UMLS:C0228740 [Term] id: UBERON:0003011 name: facial motor nucleus def: "The facial motor nucleus is a collection of neurons in the brainstem that belong to the facial nerve. These lower motor neurons innervate the muscles of facial expression and the stapedius. [WP,unvetted]." [Wikipedia:Facial_motor_nucleus] comment: see comments for facial nucleus. also check ZFA/pons subset: uberon_slim subset: vertebrate_core synonym: "branchiomotor nucleus of facial nerve" EXACT [FMA:54582] synonym: "facial motor nucleus" EXACT [FMA:54582] synonym: "facial nucleus" RELATED [Wikipedia:Facial_nucleus] synonym: "motor nucleus of VII" EXACT [FMA:54582] synonym: "motor nucleus of facial nerve" EXACT [FMA:54582] synonym: "facial nerve motor nucleus" EXACT [ZFA:0000206] synonym: "motor nucleus VII" EXACT [ZFA:0000206] synonym: "nucleus motorius nervi facialis" EXACT [ZFA:0000206] synonym: "nVII" EXACT [ZFA:0000206] xref: FMA:54582 ! Motor nucleus of facial nerve xref: NIF_GrossAnatomy:birnlex_903 ! Facial motor nucleus xref: ZFA:0000206 ! facial nerve motor nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Gray788.png/200px-Gray788.png xref: ABA:VII ! Facial motor nucleus is_a: UBERON:0000127 ! facial nucleus relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus xref: TAO:0000206 ! facial nerve motor nucleus synonym: "n. nervi facialis" RELATED LATIN [Wikipedia:Facial_motor_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray788.png [Term] id: UBERON:0003013 name: alar central lobule def: "The lobulus centralis is a small square lobule, situated in the anterior cerebellar notch. It overlaps the lingula, from which it is separated by the precentral fissure; laterally, it extends along the upper and anterior part of each hemisphere, where it forms a wing-like prolongation, the alar central lobule. [WP,unvetted]." [Wikipedia:Alar_central_lobule] subset: uberon_slim synonym: "alae of central lobule" EXACT [FMA:72517] synonym: "lobules II, III of vermis" EXACT [FMA:72517] xref: FMA:72517 ! Alar central lobule xref: NIF_GrossAnatomy:birnlex_907 ! Alar central lobule is_a: UBERON:0004003 ! cerebellum hemisphere lobule relationship: part_of UBERON:0003021 {source="FMA-abduced-lr"} ! central lobule synonym: "ala lobuli centralis" RELATED LATIN [Wikipedia:Alar_central_lobule] xref: http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray702.png [Term] id: UBERON:0003015 name: anterior quadrangular lobule synonym: "anterior crescentic lobule of cerebellum" EXACT [FMA:72516] synonym: "anterior quadrangular lobule of cerebellum" EXACT [FMA:72516] synonym: "anterior quadrangular lobule of cerebellum [H IV et V]" EXACT [FMA:72516] synonym: "anterior semilunar lobule" EXACT [FMA:72516] synonym: "semilunar lobule-1 (anterior)" EXACT [FMA:72516] xref: FMA:72516 ! Anterior quadrangular lobule xref: NIF_GrossAnatomy:birnlex_913 ! Anterior quadrangular lobule is_a: UBERON:0004004 ! cerebellum lobule is_a: UBERON:0004003 ! cerebellum hemisphere lobule synonym: "lobulus quadrangularis anterior cerebelli [h iv et v]" EXACT LATIN [FMA:TA, FMA:72516] xref: SCTID:369041006 ! Entire anterior semilunar lobule [Term] id: UBERON:0003016 name: postcommissural fornix xref: FMA:62062 ! Postcommissural fornix xref: NIF_GrossAnatomy:birnlex_914 ! Postcommissural fornix is_a: UBERON:0000052 ! fornix of brain relationship: part_of UBERON:0002430 ! lateral hypothalamic area [Term] id: UBERON:0003017 name: substantia innominata def: "The substantia innominata (literally 'unnamed substance') of Meynert is a stratum consisting partly of gray and partly of white substance, which lies below the anterior part of the thalamus and lentiform nucleus. The gross anatomical structure is called anterior perforated substance because to the naked eye looks perforated by many holes. Holes are due to many blood vessels that pass through this area. It is part of the basal forebrain. [WP,unvetted]." [Wikipedia:Substantia_innominata, Wikipedia:Substantia_innominata] subset: uberon_slim synonym: "innominate substance" EXACT [FMA:61885] synonym: "nucleus of substantia innominata" EXACT [FMA:61885] synonym: "substantia innominata of Reichert" RELATED [BTO:0002447] synonym: "substantia innominata of Reil" RELATED [BTO:0002447] xref: FMA:61885 ! Substantia innominata xref: NIF_GrossAnatomy:birnlex_915 ! Substantia innominata xref: BTO:0002447 ! substantia innominata xref: GAID:638 ! substantia innominata xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/36/Substantia_innominata_MRI.PNG/200px-Substantia_innominata_MRI.PNG xref: MESH:A08.186.211.577.820 ! substantia innominata xref: ABA:SI ! Substantia innominata xref: BM:Tel-SI ! substantia innominata is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002743 {source="WP"} ! basal forebrain relationship: part_of UBERON:0002778 {source="ABA"} ! ventral pallidum relationship: spatially_disjoint_from UBERON:0007627 {source="ABA"} ! magnocellular nucleus xref: http://upload.wikimedia.org/wikipedia/commons/3/36/Substantia_innominata_MRI.PNG [Term] id: UBERON:0003018 name: parvicellular part of ventral posteromedial nucleus synonym: "gustatory thalamic nucleus" EXACT [FMA:62207] synonym: "parvicellular part of ventral posteromedial nucleus of thalamus" EXACT [FMA:62207] synonym: "ventral posteromedial nucleus of thalamus, parvicellular part" EXACT [FMA:62207] synonym: "ventral posteromedial nucleus, parvocellular part" EXACT [FMA:62207] synonym: "ventral posteromedial thalamic nucleus, parvicellular part" EXACT [FMA:62207] synonym: "gustatory nucleus (thalamus)" EXACT [NIF_GrossAnatomy:birnlex_917] synonym: "nucleus ventralis posterior medialis thalami, pars parvicellularis" EXACT [NIF_GrossAnatomy:birnlex_917] synonym: "ventroposteromedial nucleus of the thalamus, parvicellular part" EXACT [NIF_GrossAnatomy:birnlex_917] xref: FMA:62207 ! Parvicellular part of ventral posteromedial nucleus xref: NIF_GrossAnatomy:birnlex_917 ! Parvicellular part of ventral posteromedial nucleus xref: ABA:VPMpc ! Ventral posteromedial nucleus of the thalamus, parvicellular part is_a: UBERON:0002020 ! gray matter of neuraxis synonym: "pars parvicellularis nuclei ventralis posteromedialis thalami" EXACT LATIN [FMA:TA, FMA:62207] [Term] id: UBERON:0003019 name: oral part of ventral posterolateral nucleus synonym: "ventral part of ventral lateral posterior nucleus (jones)" EXACT [] synonym: "ventral posterolateral nucleus, oral part" EXACT [FMA:62205] synonym: "ventral posterolateral thalamic nucleus, oral part" EXACT [FMA:62205] synonym: "nucleus lateralis intermedius lateralis" EXACT [NIF_GrossAnatomy:birnlex_918] synonym: "nucleus posteroventralis oralis" EXACT [NIF_GrossAnatomy:birnlex_918] synonym: "nucleus ventralis intermedius (dewulf)" EXACT [NIF_GrossAnatomy:birnlex_918] synonym: "nucleus ventralis intermedius (walker)" EXACT [NIF_GrossAnatomy:birnlex_918] synonym: "nucleus ventralis intermedius thalami" EXACT [NIF_GrossAnatomy:birnlex_918] synonym: "nucleus ventralis posterior lateralis, pars oralis" EXACT [NIF_GrossAnatomy:birnlex_918] synonym: "nucleus ventrointermedius" EXACT [NIF_GrossAnatomy:birnlex_918] xref: FMA:62205 ! Oral part of ventral posterolateral nucleus xref: NIF_GrossAnatomy:birnlex_918 ! Oral part of ventral posterolateral nucleus is_a: UBERON:0002020 ! gray matter of neuraxis [Term] id: UBERON:0003020 name: subcallosal area def: "The subcallosal area (parolfactory area of Broca, area parolfactoria) is a small triangular field on the medial surface of the hemisphere in front of the subcallosal gyrus, from which it is separated by the posterior parolfactory sulcus; it is continuous below with the olfactory trigone, and above and in front with the cingulate gyrus; it is limited anteriorly by the anterior parolfactory sulcus. [WP,unvetted]." [Wikipedia:Subcallosal_area] subset: uberon_slim synonym: "adolfactory area" EXACT [FMA:61890] synonym: "paraolfactory area" EXACT [FMA:61890] synonym: "parolfactory area" EXACT [FMA:61890] xref: FMA:61890 ! Subcallosal area xref: NIF_GrossAnatomy:birnlex_919 ! Subcallosal area xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray732.png/200px-Gray732.png is_a: UBERON:0002020 ! gray matter of neuraxis synonym: "area paraolfactoria" EXACT LATIN [FMA:TA, FMA:61890] xref: SCTID:362357004 ! Entire parolfactory area synonym: "area subcallosa, area parolfactoria" RELATED LATIN [Wikipedia:Subcallosal_area] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray732.png [Term] id: UBERON:0003022 name: lobe parts of cerebral cortex comment: check w.r.t regional part of cerebreal cortex synonym: "cerebral cortical segment" RELATED [FMA:68603] synonym: "regional organ part of cerebral cortex" RELATED [FMA:68603] synonym: "segment of cerebral cortex" RELATED [NIF_GrossAnatomy:birnlex_922] xref: FMA:68603 ! Segment of cerebral cortex xref: NIF_GrossAnatomy:birnlex_922 ! Lobe parts of cerebral cortex is_a: UBERON:0002619 ! regional part of cerebral cortex [Term] id: UBERON:0003023 ! pontine tegmentum name: pontine tegmentum def: "The pontine tegmentum is a part of the pons of the brain involved in the initiation of REM sleep. It includes the pedunculopontine nucleus and the laterodorsal tegmental nucleus, among others, and is located near the raphe nucleus and the locus ceruleus. The trapezoid body is part of the pontine tegmentum. [WP,unvetted]." [Wikipedia:Pontine_tegmentum] subset: uberon_slim synonym: "dorsal portion of pons" EXACT [FMA:71108] synonym: "tegmental portion of pons" EXACT [FMA:71108] synonym: "tegmentum of pons" EXACT [FMA:71108] xref: FMA:71108 ! Pontine tegmentum xref: NIF_GrossAnatomy:birnlex_923 ! Pontine tegmentum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9c/Brainstem_Abducens.png/200px-Brainstem_Abducens.png is_a: UBERON:0000064 ! organ part relationship: has_part UBERON:0002047 ! pontine raphe nucleus relationship: has_part UBERON:0002128 ! superior olivary complex relationship: has_part UBERON:0002148 ! locus ceruleus relationship: has_part UBERON:0002149 ! superior salivatory nucleus relationship: part_of UBERON:0000988 ! pons synonym: "tegmentum pontis" EXACT LATIN [FMA:TA, FMA:71108] xref: SCTID:362401009 ! Entire tegmental portion of pons synonym: "tegmentum pontis" RELATED LATIN [Wikipedia:Pontine_tegmentum] xref: http://upload.wikimedia.org/wikipedia/commons/9/9c/Brainstem_Abducens.png [Term] id: UBERON:0003024 name: principal part of ventral posteromedial nucleus synonym: "nucleus ventralis posteromedialis, pars prinicipalis" EXACT [NIF_GrossAnatomy:birnlex_927] xref: FMA:62208 ! Principal part of ventral posteromedial nucleus xref: NIF_GrossAnatomy:birnlex_927 ! Principal part of ventral posteromedial nucleus is_a: UBERON:0002020 ! gray matter of neuraxis [Term] id: UBERON:0003026 name: limitans nucleus synonym: "limitans thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_931] synonym: "nucleus limitans" EXACT [NIF_GrossAnatomy:birnlex_931] synonym: "nucleus limitans opticus (hassler)" EXACT [NIF_GrossAnatomy:birnlex_931] synonym: "nucleus limitans thalami" EXACT [NIF_GrossAnatomy:birnlex_931] xref: FMA:62220 ! Limitans nucleus xref: NIF_GrossAnatomy:birnlex_931 ! Limitans nucleus xref: BM:Die-Th-L ! limitans nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain xref: SCTID:369181002 ! Entire limitans nucleus [Term] id: UBERON:0003027 name: cingulate cortex def: "The cingulate cortex is a part of the brain situated in the medial aspect of the cortex. It is extended from the corpus callosum below to the cingulate sulcus above, at least anteriorly. [WP,unvetted]." [Wikipedia:Cingulate_cortex] subset: uberon_slim xref: EFO:0000343 ! cingulate cortex xref: MA:0000904 ! cingulate cortex xref: NIF_GrossAnatomy:birnlex_934 ! Cingulate cortex xref: ncithesaurus:Cingulate_Cortex ! Cingulate Cortex xref: BTO:0003975 ! cingulate cortex xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Gray727_cingulate_gyrus.png/200px-Gray727_cingulate_gyrus.png xref: BM:Tel-Cx-Cg ! cingulate cortex is_a: UBERON:0003022 ! lobe parts of cerebral cortex synonym: "gyrus cingulatus" RELATED LATIN [Wikipedia:Cingulate_cortex] xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray727_cingulate_gyrus.png xref: UMLS:C0598179 [Term] id: UBERON:0003028 name: commissure of inferior colliculus def: "A commissure that is part of a inferior colliculus [Automatically generated definition]." [OBOL:automatic] synonym: "commissure of inferior colliculi" EXACT [FMA:71115] synonym: "inferior collicular commissure" EXACT [FMA:71115] synonym: "inferior colliculus commissure" EXACT [FMA:71115] synonym: "caudal colliculus commissure" EXACT [OBOL:automatic] synonym: "commissure of caudal colliculus" EXACT [OBOL:automatic] synonym: "commissure of posterior colliculus" EXACT [OBOL:automatic] synonym: "commissure of posterior corpus quadrigeminum" EXACT [OBOL:automatic] synonym: "posterior colliculus commissure" EXACT [OBOL:automatic] synonym: "posterior corpus quadrigeminum commissure" EXACT [OBOL:automatic] xref: FMA:71115 ! Commissure of inferior colliculus xref: NIF_GrossAnatomy:birnlex_935 ! Commissure of inferior colliculus is_a: UBERON:0001020 ! commissure intersection_of: UBERON:0001020 ! commissure intersection_of: part_of UBERON:0001946 ! inferior colliculus relationship: part_of UBERON:0001946 ! inferior colliculus xref: SCTID:369260005 ! Entire commissure of inferior colliculus [Term] id: UBERON:0003029 ! stria terminalis name: stria terminalis def: "The stria terminalis (terminal stria) is a structure in the brain consisting of a band of fibers running along the lateral margin of the ventricular surface of the thalamus. Serving as a major output pathway of the amygdala, the stria terminalis runs from its corticomedial division to the ventral medial nucleus of the hypothalamus. [WP,unvetted]." [Wikipedia:Stria_terminalis] subset: uberon_slim synonym: "semicircular stria" EXACT [FMA:61974] synonym: "terminal stria" EXACT [Wikipedia:Terminal_stria] xref: FMA:61974 ! Stria terminalis xref: NIF_GrossAnatomy:birnlex_937 ! Stria terminalis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Gray683.png/200px-Gray683.png xref: BTO:0004616 ! stria terminalis xref: BM:ST ! stria terminalis xref: BM:STr ! stria terminalis is_a: UBERON:0002316 ! white matter of neuraxis synonym: "stria terminalis" RELATED LATIN [Wikipedia:Stria_terminalis] xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Gray683.png [Term] id: UBERON:0003030 name: posterior nucleus of thalamus subset: vertebrate_core synonym: "nucleus posterior thalami" EXACT [NIF_GrossAnatomy:birnlex_939] xref: FMA:62221 ! Posterior nucleus of thalamus xref: NIF_GrossAnatomy:birnlex_939 ! Posterior nucleus of thalamus xref: ZFA:0000325 ! caudal thalamic nucleus (also: UBERON:0002709 'posterior nuclear complex') xref: BM:Die-Th-Po ! posterior nucleus of thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain xref: ncithesaurus:Posterior_Nucleus_of_the_Thalamus ! Posterior Nucleus of the Thalamus xref: SCTID:424901000 ! Entire posterior nucleus of thalamus xref: TAO:0000325 ! caudal thalamic nucleus (also: UBERON:0002709 'posterior nuclear complex') synonym: "caudal thalamic nucleus" RELATED [TAO:0000325] xref: UMLS:C0262315 [Term] id: UBERON:0003031 name: submedial nucleus synonym: "gelatinosus thalamic nucleus" EXACT [FMA:62223] synonym: "submedial nucleus of thalamus" EXACT [FMA:62223] synonym: "nucleus submedius thalami" EXACT [NIF_GrossAnatomy:birnlex_946] synonym: "submedial nucleus thalamus" EXACT [NIF_GrossAnatomy:birnlex_946] synonym: "submedial thalamic nucleus" EXACT [NIF_GrossAnatomy:birnlex_946] xref: FMA:62223 ! Submedial nucleus xref: NIF_GrossAnatomy:birnlex_946 ! Submedial nucleus xref: EV:0100203 ! submedial thalamic nucleus xref: ABA:SMT ! Submedial nucleus of the thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002739 {source="ABA"} ! medial dorsal nucleus synonym: "nucleus submedialis thalami" EXACT LATIN [FMA:TA, FMA:62223] xref: SCTID:279151007 ! Entire submedial nucleus of thalamus [Term] id: UBERON:0003033 name: suprageniculate nucleus synonym: "suprageniculate thalamic nucleus" EXACT [FMA:62222] synonym: "nucleus suprageniculatus" EXACT [NIF_GrossAnatomy:birnlex_953] xref: FMA:62222 ! Suprageniculate nucleus xref: NIF_GrossAnatomy:birnlex_953 ! Suprageniculate nucleus xref: ABA:SGN ! Suprageniculate nucleus xref: BM:Die-Th-SG ! suprageniculate nucleus of thalamus is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002983 {source="ABA"} ! lateral posterior nucleus relationship: spatially_disjoint_from UBERON:0002709 {source="ABA"} ! posterior nuclear complex xref: SCTID:369180001 ! Entire suprageniculate nucleus [Term] id: UBERON:0003034 name: central dorsal nucleus synonym: "nucleus centralis dorsalis thalami" EXACT [NIF_GrossAnatomy:birnlex_956] synonym: "nucleus centralis superior lateralis" EXACT [NIF_GrossAnatomy:birnlex_956] synonym: "nucleus centralis superior lateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_956] synonym: "nucleus circularis" EXACT [NIF_GrossAnatomy:birnlex_956] xref: FMA:62169 ! Central dorsal nucleus xref: NIF_GrossAnatomy:birnlex_956 ! Central dorsal nucleus xref: ABA:NC ! Nucleus circularis is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0003035 name: regional part of cerebellar white matter subset: non_informative synonym: "segment of cerebellar white matter" EXACT [NIF_GrossAnatomy:birnlex_959] xref: FMA:72547 ! Segment of cerebellar white matter xref: NIF_GrossAnatomy:birnlex_959 ! Regional part of cerebellar white matter intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002317 ! white matter of cerebellum def: "A multi-tissue structure that is part of a white matter of cerebellum." [OBOL:automatic] [Term] id: UBERON:0003036 name: central lateral nucleus synonym: "central lateral nucleus of thalamus" EXACT [FMA:62170] synonym: "central lateral thalamic nucleus" EXACT [FMA:62170] synonym: "centrolateral thalamic nucleus" EXACT [FMA:62170] synonym: "nucleus centralis lateralis of thalamus" EXACT [NIF_GrossAnatomy:birnlex_961] synonym: "nucleus centralis lateralis thalami" EXACT [NIF_GrossAnatomy:birnlex_961] xref: FMA:62170 ! Central lateral nucleus xref: NIF_GrossAnatomy:birnlex_961 ! Central lateral nucleus xref: EV:0100205 ! central lateral thalamic nucleus xref: ABA:CL ! Central lateral nucleus of the thalamus xref: BM:Die-CL ! central lateral nucleus of the thalamus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0001923 {source="ABA"} ! central medial nucleus relationship: spatially_disjoint_from UBERON:0001924 {source="ABA"} ! paracentral nucleus relationship: spatially_disjoint_from UBERON:0001922 {source="ABA"} ! parafascicular nucleus relationship: spatially_disjoint_from UBERON:0002955 {source="ABA"} ! rhomboidal nucleus xref: SCTID:279153005 ! Entire central lateral nucleus of thalamus [Term] id: UBERON:0000446 ! septum of telencephalon name: septum of telencephalon def: "Subdivision of the telencephalon on the midline between the lateral ventricles which contains the septum pellucidum and the septal nuclei[FMA]." [FMA:61842] synonym: "septal area" EXACT [FMA:61842] synonym: "septum (NN)" EXACT [FMA:61842] synonym: "septum" BROAD [NIF_GrossAnatomy:birnlex_963] synonym: "telencephalon septum" EXACT [FMA:61842] xref: BTO:0002705 xref: FMA:61842 ! Septum of telencephalon xref: MA:0000924 ! septal cortex xref: NIF_GrossAnatomy:birnlex_963 ! Septum xref: MESH:A08.186.211.577.750 ! septum of brain is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0001869 ! cerebral hemisphere synonym: "area septalis" EXACT LATIN [FMA:TA, FMA:61842] [Term] id: UBERON:0003037 name: septum def: "a wall, dividing a cavity or structure into smaller ones[WP]." [Wikipedia:Septum] comment: general anatomical term in FMA synonym: "septa" EXACT PLURAL [] xref: FMA:86461 ! Septum xref: OpenCyc:Mx4rrqot_on_EdaAAAACs0uFOQ xref: OpenCyc:Mx4rrqot_on_EdaAAAACs0uFOQ ! septum xref: BM:Tel-Spt ! septum xref: AAO:0011127 ! septum is_a: UBERON:0000061 ! anatomical structure relationship: located_in UBERON:0002553 ! anatomical cavity property_value: has_relational_adjective "septal" xsd:string [Term] id: UBERON:0003039 ! anterior commissure anterior part name: anterior commissure anterior part def: "the horseshoe-shaped tract that connects the two olfactory bulbs." [MP:0010859] synonym: "pars anterior" BROAD [MP:0008230] synonym: "pars anterior commissurae anterioris" EXACT [MP:0008230] synonym: "anterior part of anterior commissure" EXACT [MP:0008230] synonym: "anterior commissure, anterior part" EXACT [FMA:61963] synonym: "olfactory limb of anterior commissure" EXACT [FMA:61963] synonym: "olfactory part of anterior commissure" EXACT [FMA:61963] synonym: "anterior part of anterior commissure" EXACT [FMA:61963] synonym: "anterior commissure pars anterior" EXACT [MP:0010859] xref: FMA:61963 ! Anterior part of anterior commissure xref: NIF_GrossAnatomy:birnlex_969 is_a: UBERON:0002316 ! white matter of neuraxis disjoint_from: UBERON:0006964 ! pars distalis of adenohypophysis relationship: part_of UBERON:0000935 ! anterior commissure [Term] id: UBERON:0003043 ! posterior part of anterior commissure name: posterior part of anterior commissure def: "the major forebrain commissure that connects the two temporal lobes of the cortex." [MP:0010860] synonym: "pars posterior" BROAD [MP:0008229] synonym: "anterior commissure temporal limb" EXACT [MP:0008230] synonym: "anterior commissure, posterior part" EXACT [FMA:61964] synonym: "temporal limb of anterior commissure" EXACT [FMA:61964] synonym: "anterior commissure pars posterior" EXACT [MP:0010860] xref: FMA:61964 ! Posterior part of anterior commissure xref: NIF_GrossAnatomy:birnlex_977 ! Posterior part of anterior commissure is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0000935 ! anterior commissure [Term] id: UBERON:0002968 name: central gray substance of pons synonym: "central gray of pons" EXACT [FMA:72470] synonym: "pontine central gray" EXACT [FMA:72470] xref: FMA:72470 ! Central gray substance of pons xref: NIF_GrossAnatomy:birnlex_799 ! Central gray substance of pons xref: ABA:PCG ! Pontine central gray is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0007632 {source="ABA"} ! barrington's nucleus relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus [Term] id: UBERON:0002867 name: central gray substance of medulla synonym: "medullary central gray substance" EXACT [FMA:72595] synonym: "central gray matter" EXACT [NIF_GrossAnatomy:birnlex_2638] xref: FMA:72595 ! Central gray substance of medulla xref: NIF_GrossAnatomy:birnlex_2638 ! Central gray substance of medulla is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain [Term] id: UBERON:0003040 name: central gray substance of midbrain def: "Periaqueductal gray (PAG; also called the 'central gray') is the gray matter located around the cerebral aqueduct within the midbrain. It plays a role in the descending modulation of pain and in defensive behaviour. The ascending pain and temperature fibers of the spinothalamic tract also send information to the PAG via the spinomesencephalic tract. The spinomesencephalic tract is so-named because the fibers originate in the spine and terminate in the mesencephalon, another name for the midbrain, the part of the brain in which the PAG resides. [WP,unvetted]." [Wikipedia:Periaqueductal_gray, https://sourceforge.net/tracker/?func=detail&aid=3209233&group_id=76834&atid=1205376] comment: TODO - resolve MA - see tracker subset: uberon_slim subset: vertebrate_core synonym: "anulus of cerebral aqueduct" EXACT [FMA:74510] synonym: "central (periaqueductal) gray" EXACT [FMA:74510] synonym: "periaqueductal gray" EXACT [FMA:74510] synonym: "periaqueductal gray matter" EXACT [FMA:74510] synonym: "periaqueductal gray of tegmentum" EXACT [FMA:74510] synonym: "periaqueductal grey substance" EXACT [FMA:74510] synonym: "griseum centrale" EXACT [NIF_GrossAnatomy:birnlex_973] synonym: "substantia grisea centralis" EXACT [NIF_GrossAnatomy:birnlex_973] synonym: "periaquectuctal grey" EXACT DUBIOUS [MA:0002895, https://sourceforge.net/tracker/?func=detail&aid=3209233&group_id=76834&atid=1205376] synonym: "periaqueductal grey matter" EXACT [EV:0100249] xref: FMA:74510 ! Central gray substance of midbrain xref: NIF_GrossAnatomy:birnlex_973 ! Central gray substance of midbrain xref: EFO:0002470 ! periaqueductal gray xref: GAID:585 ! periaqueductal gray xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Cn3nucleus.png/200px-Cn3nucleus.png xref: ZFA:0000518 ! griseum centrale xref: MA:0002895 ! periaquectuctal grey xref: MA:0000209 ! midbrain periaqueductal grey xref: BTO:0002701 ! midbrain central gray xref: MESH:A08.186.211.132.659.822.595 ! periaqueductal gray xref: EV:0100249 ! periaqueductal grey matter xref: ABA:PAG ! Periaqueductal gray xref: BM:MB-PAG ! periaqueductal gray is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002308 ! nucleus of brain relationship: spatially_disjoint_from UBERON:0002696 {source="ABA"} ! cuneiform nucleus relationship: spatially_disjoint_from UBERON:0002141 {source="ABA"} ! parvocellular oculomotor nucleus relationship: spatially_disjoint_from UBERON:0001715 {source="ABA"} ! oculomotor nuclear complex relationship: spatially_disjoint_from UBERON:0002722 {source="ABA"} ! trochlear nucleus relationship: spatially_disjoint_from UBERON:0001944 {source="ABA"} ! pretectal region relationship: spatially_disjoint_from UBERON:0001947 {source="ABA"} ! red nucleus relationship: spatially_disjoint_from UBERON:0002995 {source="ABA"} ! substantia nigra pars lateralis relationship: spatially_disjoint_from UBERON:0001966 {source="ABA"} ! substantia nigra pars reticulata relationship: spatially_disjoint_from UBERON:0002691 {source="ABA"} ! ventral tegmental area relationship: spatially_disjoint_from UBERON:0002438 {source="ABA"} ! ventral tegmental nucleus xref: SCTID:369233003 ! Entire periaqueductal gray matter xref: TAO:0000518 ! griseum centrale synonym: "s. grisea centralis" RELATED LATIN [Wikipedia:Periaqueductal_gray] xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Cn3nucleus.png synonym: "periaqueductal grey" EXACT [MA:0002895] synonym: "midbrain periaqueductal grey" EXACT [MA:0000209] synonym: "central grey" RELATED [MA:0000209] [Term] id: UBERON:0003041 name: trigeminal nerve fibers synonym: "central part of trigeminal nerve" EXACT [FMA:72501] synonym: "trigeminal nerve fibers" EXACT [FMA:72501] synonym: "trigeminal nerve tract" EXACT [FMA:72501] xref: FMA:72501 ! Trigeminal nerve tract xref: NIF_GrossAnatomy:birnlex_974 ! Trigeminal nerve fibers is_a: UBERON:0000064 ! organ part [Term] id: UBERON:0003044 name: uncinate fasciculus def: "The uncinate fasciculus is a white matter tract in the human brain that connects parts of the limbic system such as the hippocampus and amygdala in the temporal lobe with frontal ones such as the orbitofrontal cortex. Its function is unknown though it is affected in several psychiatric conditions. It is the last white matter tract to mature in the human brain. [WP,unvetted]." [Wikipedia:Uncinate_fasciculus] subset: uberon_slim synonym: "cerebral uncinate fasciculus" EXACT [FMA:77636] xref: FMA:77636 ! Uncinate fasciculus xref: NIF_GrossAnatomy:birnlex_983 ! Uncinate fasciculus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Gray751.png/200px-Gray751.png is_a: UBERON:0001019 ! fascicle xref: SCTID:369083001 ! Entire uncinate fasciculus xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray751.png [Term] id: UBERON:0003045 name: dorsal longitudinal fasciculus def: "The dorsal longitudinal fasciculus (DLF) (not to be confused with the medial longitudinal fasciculus) is a white matter fiber tract located within the brain stem, specifically in the dorsal brainstem tegmentum. The DLF travels through the periaqueductal gray matter. The tract is comprised of a diffuse brainstem pathway located in the periventricular gray matter comprising ascending visceral sensory axons and descending hypothalamic axons. As with all white matter tracts, the DLF consists of myelinated axons carrying information between neurons. The DLF, carries both ascending and descending fibers, conveys visceral motor and sensory signals. [WP,unvetted]." [Wikipedia:Dorsal_longitudinal_fasciculus] subset: uberon_slim subset: vertebrate_core synonym: "bundle of Schutz" EXACT [FMA:83845] synonym: "fasciculus of Schutz" EXACT [FMA:83845] synonym: "posterior longitudinal fasciculus" EXACT [FMA:83845] synonym: "DLF" RELATED [ZFA:0005266] xref: FMA:83845 ! Dorsal longitudinal fasciculus xref: NIF_GrossAnatomy:birnlex_986 ! Dorsal longitudinal fasciculus xref: ZFA:0005266 ! dorsal longitudinal fasciculus is_a: UBERON:0001019 ! fascicle is_a: UBERON:0005838 ! fasciculus of brain synonym: "fasciculus longitudinalis posterior" EXACT LATIN [FMA:TA, FMA:83845] xref: SCTID:369082006 ! Entire superior longitudinal fasciculus synonym: "fasciculus longitudinalis posterior; fasciculus longitudinalis dorsalis" RELATED LATIN [Wikipedia:Dorsal_longitudinal_fasciculus] [Term] id: UBERON:0003046 name: ventral acoustic stria synonym: "anterior acoustic stria" EXACT [FMA:72498] xref: FMA:72498 ! Ventral acoustic stria xref: NIF_GrossAnatomy:birnlex_991 ! Ventral acoustic stria is_a: UBERON:0002316 ! white matter of neuraxis synonym: "stria cochlearis anterior" EXACT LATIN [FMA:TA, FMA:72498] [Term] id: UBERON:0003047 name: regional part of pretectal region subset: non_informative def: "A regional part of brain that is part of a pretectal region [Automatically generated definition]." [OBOL:automatic] synonym: "pretectal region segment" EXACT [FMA:74519] synonym: "segment of pretectal region" EXACT [NIF_GrossAnatomy:birnlex_993] xref: FMA:74519 ! Segment of pretectal region xref: NIF_GrossAnatomy:birnlex_993 ! Regional part of pretectal region is_a: UBERON:0002966 ! regional part of midbrain tectum intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001944 ! pretectal region [Term] id: UBERON:0003048 name: regional part of hypothalamus subset: non_informative def: "A regional part of brain that is part of a hypothalamus [Automatically generated definition]." [OBOL:automatic] synonym: "hypothalamus segment" EXACT [FMA:67706] synonym: "segment of hypothalamus" EXACT [NIF_GrossAnatomy:birnlex_995] xref: FMA:67706 ! Segment of hypothalamus xref: NIF_GrossAnatomy:birnlex_995 ! Regional part of hypothalamus is_a: UBERON:0002784 ! regional part of diencephalon intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001898 ! hypothalamus xref: SCTID:360454003 ! Region of hypothalamus [Term] id: UBERON:0003049 name: collagen and cuticulin-based cuticle alt_id: UBERON:WBbt_0005755 def: "A rigid external coating which is secreted by the hypodermis, seam and some transitional epithelial cells which covers the outer body, the major openings into the body cavity from the exterior, and two large sensory bristles, the male spicules. The cuticle of the spicules, the hook, and of some portions of the spicule channels is especially rigid and is probably sclerotized. Similar sclerotic features are occasionally noted in the ventral surface of the male tail fan[WBbt]. The main structural components of the nematode cuticle are proteins, highly cross-linked collagens and specialised insoluble proteins known as cuticlins, together with glycoproteins and lipids[WP]." [UBERON:cjm, WA:dh] comment: Note that GO has a superclass protein-based cuticle development // taxonomic restriction may be too strict subset: uberon_slim synonym: "nematode cuticle" RELATED [] xref: WBbt:0005755 ! cuticle is_a: UBERON:0001002 ! cuticle relationship: only_in_taxon NCBITaxon:6231 ! Nematoda [Term] id: UBERON:0003050 ! olfactory placode name: olfactory placode def: "A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity." [XAO:0000005, Wikipedia:Nasal_placode] comment: Olfactory placodes are the only ectodermal placodes to produce glia, a cell type typically derived from neural crest // Note that NBK53171 classifies this as non-neurogenic subset: uberon_slim subset: vertebrate_core synonym: "nasal I placode" RELATED [] synonym: "nasal placode" RELATED [] synonym: "olfactory placodes" EXACT PLURAL [] synonym: "placoda nasalis" EXACT LATIN [] synonym: "placoda olfactoria" EXACT LATIN [] xref: EHDAA:1504 ! olfactory placode xref: VHOG:0000186 ! olfactory placode xref: TAO:0000048 ! olfactory placode xref: XAO:0000005 ! olfactory placode xref: ZFA:0000048 ! olfactory placode xref: EHDAA2:0001232 ! nasal placode xref: EMAPA:16543 ! olfactory placode xref: EFO:0003420 ! olfactory placode is_a: UBERON:0009955 {source="ZFA", contradicted_by="NBK53171"} ! neurogenic placode is_a: UBERON:0007497 {source="EHDAA2"} ! developing epithelial placode relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0002346 ! neural ectoderm relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm xref: AAO:0011076 ! olfactory placode property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (2) neurogenic placodes (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000186", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003051 name: ear vesicle alt_id: UBERON:0004373 def: "The saccular invagination of ectoderm from which the vertebrate inner ear develops[BTO]. Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells[ZFA]. epithelial sac of invaginated ectoderm formed from the otic placode that gives rise to the structures of the inner ear[MP]" [ZFIN:curator, MP:0009806, Wikipedia:Otic_vesicle, BTO:0002661] subset: vertebrate_core synonym: "otic vesicle" EXACT [] synonym: "otocyst" RELATED [] synonym: "auditory vesicle" RELATED [BTO:0002661] synonym: "OV" RELATED [] xref: XAO:0000006 ! otic vesicle xref: ZFA:0000051 ! otic vesicle xref: BTO:0002661 ! auditory vesicle xref: ncithesaurus:Otic_Vesicle ! Otic Vesicle xref: VHOG:0001148 ! otic vesicle xref: EHDAA2:0001342 ! otocyst xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Gray40.png/200px-Gray40.png xref: EMAPA:16669 ! otocyst is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_into UBERON:0001846 ! internal ear intersection_of: part_of UBERON:0000924 ! ectoderm relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0009123 {source="NBK53175"} ! otic cup xref: AAO:0011080 ! otic vesicle xref: SCTID:308792006 ! auditory vesicle xref: TAO:0000051 ! otic vesicle xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray40.png property_value: external_definition "Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells. Kimmel et al, 1995. (Also see Anatomical Atlas entry for ear by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000051", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "acoustic vesicle" RELATED [VHOG:0001148] property_value: external_definition "One of the paired sacs of invaginated ectoderm that develop into the membranous labyrinth of the internal ear. [Biology_online][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001148", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The inner ear develops embryonically in all vertebrates as an invagination of the ectodermal otic placode to form an otic vesicle.[well established][VHOG]" xsd:string {external_class="VHOG:0001148", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1518678 [Term] id: UBERON:0009123 ! otic cup name: otic cup is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0003069 {source="NBK53175"} ! otic placode [Term] id: UBERON:0003069 name: otic placode def: "A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII[NBK]" [NBK:NBK53175, Wikipedia:Otic_placode] comment: With the exception of the pigment cells of the stria vascularis and the secretory epithelium of the cochlea, which are of neural crest origin, all compo- nents of the inner ear derive from the otic placode. In most species the thickening of the ectoderm into a placode occurs in a region adjacent to rhombomere 5 (reviewed in Ohyama et al., 2007), while in amphibians the otic placode is centered onto rhombomere 4 (Ruiz i Altaba and Jessell, 1991).[NBK53175] subset: uberon_slim subset: vertebrate_core synonym: "placoda otica" EXACT LATIN [] synonym: "ear placode" RELATED [] synonym: "octaval placode" RELATED [ISBN10:0471888893] synonym: "octaval VIII placode" RELATED [ISBN10:0471888893] synonym: "ear/otic placode" RELATED [] synonym: "auditory placode" RELATED [] xref: EHDAA:506 ! otic placode xref: VHOG:0000235 ! otic placode xref: TAO:0000138 ! otic placode xref: XAO:0000223 ! otic placode xref: ZFA:0000138 ! otic placode xref: ncithesaurus:Otic_Placodes ! Otic Placodes xref: EMAPA:16195 ! otic placode xref: EHDAA2:0001339 ! otic placode xref: EFO:0003429 ! otic placode is_a: UBERON:0003067 {source="NBK:NBK53175", notes="invaginates"} ! dorsolateral placode relationship: part_of UBERON:0001690 ! ear xref: AAO:0011079 ! otic placode property_value: external_definition "Primordium of the ear epithelium before it hollows into the otic vesicle, present beside the hindbrain rudiment in the midsegmentation period. Kimmel et al, 1995. (Also see Anatomical Atlas entry for ear by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000138", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (2) neurogenic placodes (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000235", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1518677 [Term] id: UBERON:0010349 name: otic capsule pre-cartilage condensation synonym: "otic capsule anlage" EXACT [] is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0001846 {source="EHDAA2"} ! internal ear relationship: part_of UBERON:0003110 ! otic region xref: EHDAA2:0000833 ! otic capsule pre-cartilage condensation [Term] id: UBERON:0010351 ! otic capsule cartilage condensation name: otic capsule cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0010349 {source="EHDAA2"} ! otic capsule pre-cartilage condensation relationship: adjacent_to UBERON:0001694 {source="EHDAA2-modified"} ! petrous part of temporal bone relationship: part_of UBERON:0001846 {source="EHDAA2"} ! internal ear relationship: part_of UBERON:0003110 ! otic region xref: EHDAA2:0001333 ! otic capsule cartilage condensation xref: EMAPA:17596 ! otic capsule xref: EHDAA:4704 ! otic capsule [Term] id: UBERON:0003110 name: otic region comment: AO notes UBERONREF:0000007 has this as a syn for otic capsule synonym: "cranial vault" RELATED [ZFA:0000189] xref: XAO:0003175 ! otic region xref: ZFA:0000189 ! otic region is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium xref: AAO:0010208 ! otic region xref: TAO:0000189 ! otic region property_value: external_definition "Anatomical cluster that is a posterolateral part of the neurocranium and structurally supports the vestibuloauditory system.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010208", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Anatomical cluster that is a posterolateral part of the cranium and structurally supports the vestibuloauditory system.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000189", date_retrieved="2012-08-14", source="TAO:MAH"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps hyomandibular-otic region joint (TAO:0001947)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000189", date_retrieved="2012-08-14"} [Term] id: UBERON:0004637 ! otic capsule name: otic capsule def: "The capsule surrounding the inner ear mechanism; in elasmobranchs, it remains cartilaginous in the adult; in the embryos of higher vertebrates, it is cartilaginous at first but later becomes bony (at approximately 23 weeks in humans)[Biology-Online]. Bilaterally paired cartilage encasing the semicircular canals of the inner ear[ZFA]." [http://medical-dictionary.thefreedictionary.com/otic+capsule, ZFA:0001500, http://www.biology-online.org/dictionary/Otic_capsule] comment: Taxon notes: developmental relationships need to be checked synonym: "auditory capsule" RELATED [VHOG:0000854] synonym: "periotic capsule" RELATED [VHOG:0000854] synonym: "otic region" RELATED [] synonym: "periotic" RELATED [] synonym: "otic capsule" EXACT [ZFA:0001500] xref: VHOG:0000854 ! otic capsule is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0001694 {source="EHDAA2"} ! petrous part of temporal bone relationship: part_of UBERON:0001846 ! internal ear relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0003110 ! otic region relationship: develops_from UBERON:0010351 ! otic capsule cartilage condensation xref: AAO:0010143 ! otic capsule xref: SCTID:361515007 ! Periotic capsule property_value: external_definition "Skeletal elements surrounding the membranous labyrinth of the inner ear. Sensory capsules anterolateral to and confluent with occipital arch.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010143", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of otic and occipital (AAO:0000993)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010143", date_retrieved="2012-06-20"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of occipito-petrosal (AAO:0010831)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010143", date_retrieved="2012-06-20"} property_value: external_definition "The cartilage capsule surrounding the inner ear mechanism; in the embryos of higher vertebrates, it is cartilaginous at first but later becomes bony. [Biology_online][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000854", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Otic capsules develop around the parts of the ear that lie within the chondrocranium. This part of the ear, known as the inner ear, is composed of the semicircular ducts and associated sacs that contain the receptive cells for equilibrium and hearing (reference 1); (...) considerations have led to our rethinking issues related to the origin of several aspects of vertebrate hearing, and to the view that many basic auditory functions evolved very early in vertebrate history, and that the functions observed in more `advanced' vertebrates, such as birds and mammals, are frequently modifications of themes first encountered in fishes, and perhaps even more ancestral animals.[well established][VHOG]" xsd:string {external_class="VHOG:0000854", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.235\, DOI:10.1016/S0378-5955(00)00168-4 Fay RR\, Popper AN\, Evolution of hearing in vertebrates: the inner ears and processing. Hearing research (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005410 ! cartilaginous otic capsule name: cartilaginous otic capsule comment: in elasmobranchs, the otic capsule remains cartilaginous in the adult; in the embryos of higher vertebrates, it is cartilaginous at first but later becomes bony (at approximately 23 weeks in humans). todo - check EMAPA subset: vertebrate_core synonym: "auditory capsule" EXACT [ZFA:0001500] xref: ZFA:0001500 ! auditory capsule xref: EMAPA:18803 ! otic cartilage is_a: UBERON:0003932 ! cartilaginous elemenet of chondrocranium is_a: UBERON:0004637 ! otic capsule xref: TAO:0001500 ! auditory capsule property_value: external_definition "Bilaterally paired cartilage encasing the semicircular canals of the inner ear.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001500", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: develops_from neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001500", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: part_of neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001500", date_retrieved="2012-08-14"} [Term] id: UBERON:0005411 name: bony otic capsule comment: in elasmobranchs, the otic capsule remains cartilaginous in the adult; in the embryos of higher vertebrates, it is cartilaginous at first but later becomes bony (at approximately 23 weeks in humans) xref: MA:0000252 ! otic capsule is_a: UBERON:0002481 ! bone tissue is_a: UBERON:0004637 ! otic capsule relationship: develops_from UBERON:0005410 ! cartilaginous otic capsule [Term] id: UBERON:0004746 name: prootic bone def: "Paired, endochondral bones forming the anterior, and lateral walls of the otic capsules." [AAO:0000514] synonym: "prootic" EXACT [AAO:0000514] xref: AAO:0000514 ! prootic xref: ZFA:0000575 ! prootic xref: EFO:0003542 ! prootic xref: TAO:0000575 ! prootic is_a: UBERON:0002513 ! endochondral bone relationship: develops_from UBERON:0004637 ! otic capsule relationship: part_of UBERON:0003110 ! otic region relationship: part_of UBERON:0002241 {source="Kardong"} ! chondrocranium relationship: part_of UBERON:0001703 ! neurocranium relationship: develops_from UBERON:0005410 ! cartilaginous otic capsule property_value: external_definition "Endochondral bone that sutures with the pterosphenoid anteriorly, the sphenotic and pterotic dorsally, the parasphenoid ventrally, the basioccipital postero-ventrally, the exoccipital posteriorly, and occasionally, with the intercalar posteriorly. The dorsal edge of the prootic contributes to the hyomandibular facet. The prootic bears foramina that accommodate branches of the trigeminal and facial nerves. The prootic is a paired bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000575", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from basal plate cartilage (TAO:0001425)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000575", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: develops_from neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000575", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: part_of neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000575", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps orbitosphenoid-prootic joint (TAO:0001794)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000575", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps prootic-pterosphenoid joint (TAO:0002033)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000575", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps prootic-exoccipital joint (TAO:0002034)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000575", date_retrieved="2012-08-14"} synonym: "prootics" RELATED PLURAL [TAO:0000575] [Term] id: UBERON:0010910 name: opisthotic def: "Posterior ossification of the otic capsule." [AAO:0010835, http://palaeos.com/vertebrates/bones/braincase/opisthotic.html] comment: Taxon notes: teleost fishes have a bone which is called the opisthotic. However, it is not homologous to the tetrapod opisthotic and the teleost otic capsule is all of a piece[palaeos] - see TAO:0000474 - intercalar "Small membrane bone homologous with a cartilage bone in more basal fishes (Patterson, 1977). Situated between the exoccipital and the pterotic at point of attachment of short ligament that originates on the ventral arm of the posttemporal." is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004637 {source="AAO"} ! otic capsule xref: AAO:0010835 ! opisthotic [Term] id: UBERON:0009848 name: zona limitans intrathalamica def: "A narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon." [GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06, GO_REF:0000021, PMID:11425897, PMID:16452095, GO:0022006, Wikipedia:Zona_limitans_intrathalamica] synonym: "ZLI" EXACT [GO:0022006] intersection_of: UBERON:0006800 ! anatomical line intersection_of: adjacent_to UBERON:0001900 ! subthalamus intersection_of: adjacent_to UBERON:0004703 ! dorsal thalamus xref: ZFA:0001344 ! zona limitans intrathalamica xref: TAO:0001344 ! zona limitans intrathalamica property_value: external_definition "The border between the dorsal and ventral thalamus.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001344", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0009774 ! embryonic midbrain hindbrain boundary name: embryonic midbrain hindbrain boundary comment: merge with presumptive midbrain hindbrain boundary? is_a: UBERON:0006800 {source="ZFA"} ! anatomical line relationship: part_of UBERON:0006238 ! future brain [Term] id: UBERON:0007281 name: presumptive midbrain hindbrain boundary synonym: "presumptive MHB" EXACT [UBERON:cjm] xref: ZFA:0001187 ! presumptive midbrain hindbrain boundary xref: EFO:0003446 ! presumptive midbrain hindbrain boundary intersection_of: UBERON:0009774 ! embryonic midbrain hindbrain boundary intersection_of: part_of UBERON:0002346 ! neural ectoderm xref: XAO:0004086 ! presumptive midbrain-hindbrain boundary xref: TAO:0001187 ! presumptive midbrain hindbrain boundary def: "An embryonic midbrain hindbrain boundary that is part of a neurectoderm." [OBOL:automatic] [Term] id: UBERON:0009615 ! midbrain hindbrain boundary neural plate name: midbrain hindbrain boundary neural plate comment: todo: developmental relationships for lines synonym: "midbrain-hindbrain boundary neural plate" EXACT [ZFA:0007044] synonym: "MHB neural plate" EXACT [UBERON:cjm] xref: TAO:0007044 ! midbrain hindbrain boundary neural plate intersection_of: UBERON:0009774 ! embryonic midbrain hindbrain boundary intersection_of: part_of UBERON:0003075 ! neural plate relationship: develops_from UBERON:0007281 {source="ZFA"} ! presumptive midbrain hindbrain boundary relationship: part_of UBERON:0003075 {source="ZFA"} ! neural plate xref: ZFA:0007044 ! midbrain hindbrain boundary neural plate def: "An embryonic midbrain hindbrain boundary that is part of a neural plate." [OBOL:automatic] [Term] id: UBERON:0003052 ! midbrain-hindbrain boundary name: midbrain-hindbrain boundary def: "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." [GO:0021555] comment: editor note: consider adding class for organizer. Consider adding separate class for isthmus as a structure subset: uberon_slim subset: vertebrate_core synonym: "isthmus" RELATED [] synonym: "isthmus/MHB" RELATED [Geisha:syn, NCBITaxon:8782] synonym: "MHB" EXACT [] synonym: "midbrain hindbrain boundary" EXACT [] synonym: "mid-hindbrain boundary" EXACT [] synonym: "mid-hindbrain junction" EXACT [] xref: VHOG:0000649 ! midbrain-hindbrain boundary xref: TAO:0000042 ! midbrain hindbrain boundary xref: XAO:0000016 ! midbrain-hindbrain boundary xref: ZFA:0000042 ! midbrain hindbrain boundary xref: EHDAA2:0004395 ! isthmus xref: EHDAA:5789 ! isthmus is_a: UBERON:0006800 {source="ZFA"} ! anatomical line intersection_of: UBERON:0006800 ! anatomical line intersection_of: adjacent_to UBERON:0001891 ! midbrain intersection_of: adjacent_to UBERON:0002028 ! hindbrain relationship: develops_from UBERON:0009615 {source="ZFA"} ! midbrain hindbrain boundary neural plate relationship: part_of UBERON:0000955 {source="ZFA"} ! brain disjoint_from: UBERON:0001609 ! isthmus of thyroid gland xref: AAO:0011064 ! midbrain-hindbrain boundary synonym: "isthmo-cerebellar region" RELATED [VHOG:0000649] property_value: homology_notes "Lampreys also have an MHB [midbrain hindbrain boundary], expressing a similar repertoire of regulatory gene cognates as in gnathostomes.[well established][VHOG]" xsd:string {external_class="VHOG:0000649", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y\, Uchida K\, Rijli FM and Kuratani S\, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005284 name: brain vasculature def: "A vasculature that is part of a brain [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "vasculature of brain" EXACT [FMA:242007] xref: TAO:0000099 ! brain vasculature xref: ZFA:0000099 ! brain vasculature xref: FMA:242007 ! Vasculature of brain xref: EFO:0003491 ! brain vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000955 ! brain [Term] id: UBERON:0005283 name: tela choroidea def: "A structure found in the walls of the ventricles of the brain, consisting of part of the meninges (pia mater in mammals) plus ependyma[cjm]." [Wikipedia:Tela_chorioidea, http://isc.temple.edu/neuroanatomy/lab/embryo_new/choroid/, ISBN10:0471888893] comment: Vascularized tela choroidea is choroid plexus. AO notes: Note that the structure in ZFA may be different. subset: vertebrate_core synonym: "tela chorioidea" RELATED [FMA:242849] xref: ZFA:0000447 ! tela chorioidea xref: TAO:0000447 ! tela chorioidea xref: FMA:242849 ! tela choroidea is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0005358 {source="FMA"} ! ventricle of nervous system relationship: overlaps UBERON:0010743 ! meningeal cluster relationship: overlaps UBERON:0001886 ! choroid plexus property_value: external_definition "Portion of tissue that is part of the primitive meninx which forms a fold, roofing a ventricle of the brain and supporting the choroid plexus[ZFA:0000447]." xsd:string {source="ZFA:0000447"} [Term] id: UBERON:0005286 name: tela choroidea of midbrain cerebral aqueduct def: "Tela choroidea that lines the tectal ventricle." [ZFIN:curator] synonym: "tela choroidea tectal ventricle" EXACT [ZFA:0005157] synonym: "tela chorioidea tectal ventricle" EXACT [ZFA:0005157] synonym: "tela choroidea of cerebral aqueduct" EXACT [UBERON:cjm] synonym: "tela chorioidea tectal ventricle" EXACT [ZFA:0005157] xref: ZFA:0005157 ! tela chorioidea tectal ventricle xref: TAO:0005157 ! tela chorioidea tectal ventricle is_a: UBERON:0005283 ! tela choroidea intersection_of: UBERON:0005283 ! tela choroidea intersection_of: part_of UBERON:0002289 ! midbrain cerebral aqueduct property_value: external_definition "Tela chorioidea that lines the tectal ventricle.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005157", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005287 name: tela choroidea of fourth ventricle def: "Tela chorioidea that lines the fourth ventricle[ZFA]. The tela chorioidea of the fourth ventricle is the name applied to the triangular fold of pia mater which is carried upward between the cerebellum and the medulla oblongata. It consists of two layers, which are continuous with each other in front, and are more or less adherent throughout: The posterior layer covers the antero-inferior surface of the cerebellum. The anterior layer is applied to the structures which form the lower part of the roof of the ventricle, and is continuous inferiorly with the pia mater on the inferior peduncles and closed part of the medulla[WP]." [ZFIN:curator, Wikipedia:Tela_chorioidea_of_fourth_ventricle] subset: vertebrate_core synonym: "tela choroidea fourth ventricle" EXACT [] synonym: "tela chorioidea fourth ventricle" EXACT [] synonym: "tela choroidea of fourth ventricle" EXACT [] synonym: "choroid membrane" EXACT [FMA:78493] synonym: "choroid membrane of fourth ventricle" EXACT [FMA:78493] xref: ZFA:0005158 ! tela chorioidea fourth ventricle xref: FMA:78493 ! tela choroidea of fourth ventricle is_a: UBERON:0005283 ! tela choroidea intersection_of: UBERON:0005283 ! tela choroidea intersection_of: part_of UBERON:0002422 ! fourth ventricle relationship: part_of UBERON:0002422 ! fourth ventricle synonym: "tela choroidea ventriculi quarti" EXACT LATIN [FMA:TA, FMA:78493] synonym: "tela choroidea" BROAD [FMA:TA, FMA:78493] xref: SCTID:362321009 ! Entire tela choroidea of fourth ventricle xref: TAO:0005158 ! tela chorioidea fourth ventricle synonym: "tela choroidea ventriculi quarti" RELATED LATIN [Wikipedia:Tela_chorioidea_of_fourth_ventricle] property_value: external_definition "Tela chorioidea that lines the fourth ventricle.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005158", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005288 name: tela choroidea of third ventricle def: "Tela chorioidea that lines the third ventricle[ZFA]. The part of the choroid plexus in relation to the body of the ventricle forms the vascular fringed margin of a triangular process of pia mater, named the tela chorioidea of the third ventricle, and projects from under cover of the lateral edge of the fornix. Blood is supplied by branches from the superior cerebellar artery[WP]." [ZFIN:curator, Wikipedia:Tela_chorioidea_of_third_ventricle] subset: vertebrate_core synonym: "tela choroidea third ventricle" EXACT [] synonym: "tela chorioidea of third ventricle" EXACT [] synonym: "choroid membrane of third ventricle" EXACT [FMA:78463] synonym: "tela chorioidea third ventricle" EXACT [ZFA:0005159] xref: ZFA:0005159 ! tela chorioidea third ventricle xref: FMA:78463 ! tela choroidea of third ventricle is_a: UBERON:0005283 ! tela choroidea intersection_of: UBERON:0005283 ! tela choroidea intersection_of: part_of UBERON:0002286 ! third ventricle relationship: part_of UBERON:0002286 ! third ventricle synonym: "tela choroidea ventriculi tertii" EXACT LATIN [FMA:TA, FMA:78463] xref: SCTID:362320005 ! Entire tela choroidea of third ventricle xref: TAO:0005159 ! tela chorioidea third ventricle synonym: "tela choroidea ventriculi tertii" RELATED LATIN [Wikipedia:Tela_chorioidea_of_third_ventricle] xref: http://upload.wikimedia.org/wikipedia/commons/6/60/Gray723.png property_value: external_definition "Tela chorioidea that lines the third ventricle.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005159", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005289 name: tela choroidea of telencephalic ventricle def: "Tela chorioidea that lines the telencephalic ventricle." [ZFIN:curator] subset: vertebrate_core synonym: "tela chorioidea of telencephalic ventricle" EXACT [] synonym: "tela choroidea telencephalic ventricle" EXACT [] synonym: "tela choroidea of lateral ventricle" EXACT [FMA:83712] synonym: "tela chorioidea of lateral ventricle" EXACT [] synonym: "tela chorioidea telencephalic ventricle" EXACT [ZFA:0005160] xref: ZFA:0005160 ! tela chorioidea telencephalic ventricle xref: FMA:83712 ! tela choroidea of lateral ventricle is_a: UBERON:0005283 ! tela choroidea intersection_of: UBERON:0005283 ! tela choroidea intersection_of: part_of UBERON:0002285 ! telencephalic ventricle xref: SCTID:362319004 ! Entire tela choroidea of lateral ventricle xref: TAO:0005160 ! tela chorioidea telencephalic ventricle [Term] id: UBERON:0001886 name: choroid plexus def: "A network formed by blood vessels and the tela choroidea which secretes CSF into the ventricular spaces." [Wikipedia:Choroid_plexus, ISBN10:0471888893] comment: TODO - check relationship to ventricle. Check subclass - ZFA says vasculature. Note that FMA:61934 (choroid plexus of cerebral hemisphere) has exact synonym 'choroid plexus' but it is not clear that this belongs here, as the fourth ventricle is not in the cerebral hemisphere subset: uberon_slim subset: vertebrate_core synonym: "chorioid plexus" EXACT [FMA:61934] synonym: "choroid plexus of cerebral hemisphere" RELATED [FMA:61934] synonym: "ventricular choroid plexus" RELATED [] synonym: "plexus choroideus" EXACT LATIN [FMA:TA, FMA:61934] synonym: "plexus choroideus" RELATED LATIN [Wikipedia:Choroid_plexus] xref: BTO:0000258 xref: FMA:61934 ! Choroid plexus of cerebral hemisphere xref: GAID:607 ! choroid plexus xref: MA:0000823 ! choroid plexus xref: TAO:0001443 ! choroid plexus xref: ZFA:0001443 ! choroid plexus xref: ncithesaurus:Choroid_Plexus ! Choroid Plexus xref: EFO:0001915 ! choroid plexus xref: VHOG:0001377 ! choroid plexus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Gray708.svg/200px-Gray708.svg.png xref: MESH:A08.186.211.276.298 ! choroid plexus is_a: UBERON:0005629 ! vascular plexus relationship: part_of UBERON:0004086 ! brain ventricle relationship: part_of UBERON:0005283 ! tela choroidea xref: SCTID:264450003 ! Entire choroid plexus xref: http://upload.wikimedia.org/wikipedia/commons/b/b9/Gray708.svg property_value: external_definition "A tuft of capillaries that project into the ventricles of the brain and secretes cerebral spinal fluid. The choroid plexus is covered by a cuboidal epithelium which maintains the integrity of the blood-brain barrier.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001443", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "choroidal" xsd:string property_value: external_definition "Fringe of the tela choroidea of the brain ventricles[MP]" xsd:string {source="MP:0000820"} xref: UMLS:C0008524 [Term] id: UBERON:0003911 name: choroid plexus epithelium def: "An epithelium that is part of a choroid plexus [Automatically generated definition]." [OBOL:automatic] synonym: "epithelium of choroid plexus" EXACT [FMA:242811] synonym: "chorioid plexus of cerebral hemisphere epithelial tissue" EXACT [OBOL:automatic] synonym: "chorioid plexus of cerebral hemisphere epithelium" EXACT [OBOL:automatic] synonym: "choroid plexus epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelial tissue of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "epithelial tissue of choroid plexus" EXACT [OBOL:automatic] synonym: "epithelium of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] xref: MA:0000824 ! choroid plexus epithelium xref: FMA:242811 ! epithelium of choroid plexus xref: ncithesaurus:Choroid_Plexus_Epithelium ! Choroid Plexus Epithelium is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001886 xref: UMLS:C1516506 [Term] id: UBERON:0013151 name: choroidal artery synonym: "choroid artery" EXACT [] synonym: "artery of choroid plexus" EXACT [] intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001886 ! choroid plexus xref: SCTID:244210009 ! Entire choroidal artery xref: ncithesaurus:Choroidal_Artery ! choroidal artery xref: UMLS:C0226164 [Term] id: UBERON:0001776 name: optic choroid def: "vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]." [Wikipedia:Choroid] comment: check choroid vs choroid layer; check ZFA/TAO placement - no homology assertion in VHOG. Note this is entirely in the posterior region of eyeball in ZFA subset: uberon_slim subset: vertebrate_core synonym: "choroidea" EXACT [Wikipedia:Choroid] synonym: "choroid coat" EXACT [Wikipedia:Choroid] synonym: "posterior uvea" EXACT [Wikipedia:Uvea#Regions] synonym: "optic choroid" RELATED [ZFA:0005229] synonym: "chorioid" RELATED [BTO:0001829] synonym: "eye choroid" EXACT [VHOG:0001568] synonym: "choroidea" RELATED LATIN [Wikipedia:Choroid] synonym: "choroid" EXACT [MA:0000263] xref: VHOG:0001568 ! eye choroid xref: FMA:58298 ! Choroid xref: GAID:913 ! choroid xref: MA:0000263 ! choroid xref: ncithesaurus:Choroid xref: TAO:0005229 ! optic choroid xref: ZFA:0005229 ! optic choroid xref: BTO:0001829 ! choroid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png xref: EMAPA:19077 ! choroid xref: EMAPA:25087 ! choroid layer xref: MESH:A09.371.894.223 ! choroid xref: EV:0100347 ! choroid xref: SCTID:181172003 ! Entire choroid xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg is_a: UBERON:0002049 ! vasculature relationship: adjacent_to UBERON:0000966 ! retina relationship: adjacent_to UBERON:0001773 ! sclera relationship: adjacent_to UBERON:0011892 ! anterior uvea relationship: part_of UBERON:0001768 {source="MA"} ! uvea relationship: overlaps UBERON:0001802 {source="Wikipedia"} ! posterior segment of eyeball property_value: has_relational_adjective "choroidal" xsd:string xref: UMLS:C0008520 [Term] id: UBERON:0013399 name: blood vessel layer of choroid synonym: "Haller's layer" NARROW [FMA:58435] synonym: "lamina vasculosa (choroid)" EXACT [FMA:58435] synonym: "lamina vasculosa of choroid" EXACT [FMA:58435] synonym: "outer layer of choroid proper" EXACT [FMA:58435] synonym: "Sattler's layer" NARROW [FMA:58435] synonym: "vessel layer of choroid" EXACT [FMA:58435] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0001776 {source="FMA"} ! optic choroid relationship: composed_primarily_of UBERON:0001981 ! blood vessel xref: FMA:58435 ! vascular lamina of choroid property_value: external_definition "a layer of medium-diameter blood vessels of the choroid, a layer of the eye[Wikipedia:Sattler's_layer]." xsd:string {source="Wikipedia:Sattler's_layer"} [Term] id: UBERON:0010078 name: optic choroid vascular plexus alt_id: ZFA:0005228 comment: Editor notes: Consider merging with capillary layer. See https://sourceforge.net/tracker/?group_id=76834&atid=1127722. Consider choriocapillaris complex synonym: "CVP" EXACT ABBREVIATION [ZFA:0005094] synonym: "choroid vasculature" RELATED [ZFA:0005094] synonym: "capillary lamina of choroid" RELATED [XAO:0004176] synonym: "choriocapillaris" RELATED [XAO:0004176] synonym: "optic choroid vascular plexus" RELATED [XAO:0004176] synonym: "choroidal vascular plexus" RELATED [TAO:0005094] synonym: "choroid vascular plexus" RELATED [] xref: TAO:0005094 ! choroidal vascular plexus is_a: UBERON:0002203 {source="ZFA"} ! vasculature of eye is_a: UBERON:0005629 {source="XAO"} ! vascular plexus relationship: part_of UBERON:0001776 {source="ZFA"} ! optic choroid relationship: part_of UBERON:0002200 {source="XAO"} ! vasculature of head xref: XAO:0004176 ! choroidal vascular plexus xref: ZFA:0005094 ! optic choroid vascular plexus disjoint_from: UBERON:0001886 ! choroid plexus property_value: external_definition "Is an ocular vasculature that develops adjacent to the pigment epithelium of the eye. The optic choroid vascular plexus develops from the primitive mesencephalic artery. Initially blood enters from the mesencephalic central artery, and the dorsal ciliary vein. The plexus drains via the ophthalmic vein. The plexus supplies blood to the retina[ZFA:0005094]." xsd:string {source="ZFA:0005094"} property_value: taxon_notes "The choroid of teleosts is a connective tissue layer rich in blood vessels, and one or two choroidal glands." xsd:string {source="PMID:14738502"} property_value: external_definition "A plexus of capillaries that is visible anteromedial to the eye. The choroid is the vascular layer of the eye, containing connective tissue, and lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[XAO:0004176]." xsd:string {source="XAO:0004176"} [Term] id: UBERON:0005336 name: capillary layer of choroid def: "The capillary lamina of choroid or choriocapillaris is a layer of capillaries that is immediately adjacent to Bruch's membrane in the choroid." [Wikipedia:Capillary_lamina_of_choroid] synonym: "choriocapillaris" RELATED [Wikipedia:Capillary_lamina_of_choroid] synonym: "lamina choriocapillaris" RELATED [] synonym: "capillary layer of choroid" EXACT [FMA:58437] synonym: "inner layer of choroid proper" EXACT [FMA:58437] synonym: "capillary lamina of choroid or choriocapillaris" RELATED [] synonym: "lamina choroidocapillaris" RELATED LATIN [Wikipedia:Capillary_lamina_of_choroid] synonym: "capillary lamina of choroid" EXACT [FMA:58437] xref: FMA:58437 ! capillary lamina of choroid is_a: UBERON:0004923 ! organ component layer relationship: overlaps UBERON:0003957 {source="Wikipedia:Bruch's_membrane", notes="overlaps via basement membrane. consider also adjacency"} ! Bruch's membrane relationship: part_of UBERON:0001776 {source="FMA"} ! optic choroid relationship: composed_primarily_of UBERON:0001982 ! capillary xref: SCTID:280899009 ! Entire lamina choroidocapillaris disjoint_from: UBERON:0001886 ! choroid plexus [Term] id: UBERON:0003957 ! Bruch's membrane name: Bruch's membrane def: "A transparent, nearly structureless innermost layer of the choroid in contact with the pigmented layer of the retina. Bruch's membrane consists of five layers (from inside to outside): 1. the basement membrane of the retinal pigment epithelium; 2. the inner collagenous zone; 3. a central band of elastic fibers; 4. the outer collagenous zone; 5. the basement membrane of the choriocapillaris. The retinal pigment epithelium transports metabolic waste from the photoreceptors across Bruch's membrane to the choroid." [MP:0005239, Wikipedia:Bruch's_membrane] comment: TODO - see also subset: vertebrate_core synonym: "basal lamina of choroid" EXACT [FMA:58438] synonym: "lamina basilis" BROAD [FMA:58438] synonym: "Bruch's basal membrane" EXACT [FMA:58438] synonym: "Bruch membrane" EXACT [MESH:A09.371.894.223.250] synonym: "lamina basalis (choroid)" EXACT [FMA:58438] xref: GAID:914 ! bruch membrane xref: FMA:58438 ! Basal lamina of choroid xref: MESH:A09.371.894.223.250 ! bruch membrane xref: ZFA:0005562 ! Bruch's membrane is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0001776 ! optic choroid relationship: adjacent_to UBERON:0001782 ! pigmented layer of retina xref: SCTID:280652000 ! Entire Bruch's basal membrane [Term] id: UBERON:0013398 name: choroidal gland comment: Requires review intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001776 ! optic choroid property_value: external_definition "Teleosts bear a body of capillary adjacent to the optic nerve called the choroidal gland. Though its function is not known, it is believed to be a supplemental oxygen carrier[http://en.wikipedia.org/wiki/Choroid#In_bony_fish]." xsd:string {source="http://en.wikipedia.org/wiki/Choroid#In_bony_fish"} property_value: external_definition "a gland on the dorsal half of the fish eyeball[http://en.academic.ru/dic.nsf/en_ichthyology/2916/choroid]l" xsd:string {source="http://en.academic.ru/dic.nsf/en_ichthyology/2916/choroid"} [Term] id: UBERON:0003947 name: brain ventricle/choroid plexus def: "the brain ventricles or their associated choroid plexuses" [MP:0002200] comment: TODO - check relationship between CP and BV. If this is part of then this class should be obsoleted is_a: UBERON:0000061 ! anatomical structure union_of: UBERON:0004086 ! brain ventricle union_of: UBERON:0001886 ! choroid plexus relationship: part_of UBERON:0000955 ! brain [Term] id: UBERON:0005358 ! ventricle of nervous system name: ventricle of nervous system synonym: "region of wall of ventricular system of neuraxis" RELATED [FMA:242770] xref: FMA:242770 ! Region of wall of ventricular system of neuraxis is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0004086 ! brain ventricle name: brain ventricle def: "one of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid" [] comment: Note that FMA draws the distinction between e.g. 'fourth ventricle' and 'cavity of fourth ventricle'. The latter is a cavity, and part of the former, which is a region. The superclass of 'fourth ventricle' is_a 'region of ventricular system of the brain'. We place this class here, although it is not equivalent to ventricles, as it includes ventricle bodies. synonym: "cerebral ventricle" EXACT [HP:0002118] synonym: "region of ventricular system of brain" EXACT [FMA:78447] xref: MA:0000818 ! brain ventricle xref: BTO:0001442 ! brain ventricle xref: FMA:78447 ! Region of ventricular system of brain xref: ncithesaurus:Ventricle_Brain xref: OpenCyc:Mx4rvmTY65wpEbGdrcN5Y29ycA ! brain ventricle xref: NIF_GrossAnatomy:birnlex_1356 ! Cerebral ventricular cavity xref: MESH:A08.186.211.276 ! cerebral ventricle xref: EFO:0001914 ! brain ventricle is_a: UBERON:0005358 ! ventricle of nervous system relationship: part_of UBERON:0005282 ! ventricular system of brain xref: SCTID:180929003 ! Entire ventricle of brain xref: UMLS:C0007799 [Term] id: UBERON:0005281 ! ventricular system of central nervous system name: ventricular system of central nervous system def: "a set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord[WP]." [Wikipedia:Ventricular_system] comment: todo - resolve space vs structure conflation. We follow FMA in making this and the various ventricles a structure - it follows from this that strutures such as the tela choroidea and choroid plexuses can be part of the ventricles and ventricular system. Note: see also the class 'neuraxis cavity' subset: vertebrate_core synonym: "ventriculi cerebri" RELATED LATIN [Wikipedia:Ventricular_system] synonym: "ventricle system" RELATED [Wikipedia:Ventricular_system] synonym: "ventricular system of neuraxis" EXACT [FMA:242675] synonym: "ventricular system" EXACT [ZFA:0001261] synonym: "CNS ventricular system" EXACT [EHDAA2:0004362] xref: TAO:0001261 ! ventricular system xref: ZFA:0001261 ! ventricular system xref: FMA:242675 ! ventricular system of neuraxis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Gray734.png/200px-Gray734.png xref: EV:0100306 ! ventricular system xref: EFO:0003650 ! ventricular system is_a: UBERON:0000467 {source="ZFA"} ! anatomical system relationship: part_of UBERON:0001017 ! central nervous system xref: EHDAA2:0004362 ! CNS ventricular system xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray734.png [Term] id: UBERON:0005282 ! ventricular system of brain name: ventricular system of brain synonym: "brain ventricular system" EXACT [VHOG:0000005] xref: FMA:242787 ! Ventricular system of brain xref: VHOG:0000005 ! brain ventricular system is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0005281 ! ventricular system relationship: part_of UBERON:0000955 ! brain property_value: homology_notes "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000005", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.381-382\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002561 name: neuraxis cavity def: "The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube" [UBERON:cjm] synonym: "cavity of ventricular system of neuraxis" EXACT [FMA:75007] synonym: "neuraxis lumen" EXACT [] synonym: "neuraxis cavity" EXACT [FMA:75007] synonym: "cavity of neuraxis" EXACT [FMA:75007] xref: FMA:75007 ! Cavity of neuraxis xref: NIF_GrossAnatomy:birnlex_1029 ! Neuraxis cavity intersection_of: UBERON:0002558 ! organ cavity intersection_of: enclosed_by UBERON:0001017 ! central nervous system relationship: part_of UBERON:0001017 ! central nervous system relationship: develops_from UBERON:0003842 {source="cjm"} ! neural tube lumen [Term] id: UBERON:0004860 name: obsolete brain ventricular zone is_obsolete: true consider: UBERON:0003053 ! ventricular zone [Term] id: UBERON:0004061 ! neural tube mantle layer name: neural tube mantle layer def: "the layer of glia and differentiating neurons that will form the gray matter of the spinal cord; this lies between the ventricular and marginal layers and includes the basal and alar plates" [MP:0009690] xref: EMAPA:17148 ! mantle layer of lateral wall of neural tube of future spinal cord of central nervous system of nervous system of organ system synonym: "neural tube intermediate zone" EXACT [MP:0009690] is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001049 ! neural tube relationship: adjacent_to UBERON:0004060 ! neural tube ventricular layer relationship: adjacent_to UBERON:0004062 ! neural tube marginal layer [Term] id: UBERON:0004060 ! neural tube ventricular layer name: neural tube ventricular layer def: "the layer of undifferentiated, proliferating cells that line the neural tube lumen" [MP:0009689] comment: consider merging with 'ventricular zone' xref: EMAPA:17152 ! ventricular layer of lateral wall of neural tube of future spinal cord of central nervous system of nervous system of organ system xref: EMAPA:16783 ! ventricular layer synonym: "neural tube ependymal zone" EXACT [MP:0009689] synonym: "neural tube ventricular zone" RELATED [MP:0009689] is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001049 ! neural tube relationship: adjacent_to UBERON:0003842 ! neural lumen [Term] id: UBERON:0004062 ! neural tube marginal layer name: neural tube marginal layer def: "the outermost layer of the neural tube that contains nerve fibers and will form the white matter" [MP:0009691] synonym: "neural tube marginal zone" EXACT [MP:0009691] xref: EMAPA:17151 ! marginal layer of lateral wall of neural tube of future spinal cord of central nervous system of nervous system of organ system is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001049 ! neural tube [Term] id: UBERON:0005883 ! neural tube lateral wall mantle layer name: neural tube lateral wall mantle layer comment: TODO - expand subtypes post EHDAA2-revision, check lateral wall xref: EHDAA2:0001261 ! neural tube lateral wall mantle layer is_a: UBERON:0004061 ! neural tube mantle layer relationship: part_of UBERON:0005496 ! neural tube lateral wall [Term] id: UBERON:0009580 name: diencephalon mantle layer synonym: "diencephalon lateral wall mantle layer" EXACT [] is_a: UBERON:0005883 ! neural tube lateral wall mantle layer relationship: part_of UBERON:0005591 {source="EMAPA"} ! diencephalon lateral wall xref: EMAPA:16906 ! mantle layer of lateral wall of diencephalon of forebrain xref: EHDAA2:0000397 ! diencephalon mantle layer xref: VHOG:0000912 ! mantle layer lateral wall diencephalon synonym: "mantle layer lateral wall diencephalon" EXACT [VHOG:0000912] [Term] id: UBERON:0009581 name: midbrain mantle layer synonym: "midbrain lateral wall mantle layer" EXACT [] is_a: UBERON:0005883 ! neural tube lateral wall mantle layer relationship: part_of UBERON:0005495 {source="EMAPA"} ! midbrain lateral wall xref: EMAPA:16977 ! mantle layer of lateral wall of midbrain xref: EHDAA2:0001172 ! midbrain mantle layer xref: VHOG:0000910 ! mantle layer lateral wall midbrain synonym: "mantle layer lateral wall midbrain" EXACT [VHOG:0000910] synonym: "mantle layer lateral wall mesencephalon" RELATED [VHOG:0000910] [Term] id: UBERON:0009583 name: spinal cord mantle layer synonym: "spinal cord lateral wall mantle layer" EXACT [] is_a: UBERON:0005883 ! neural tube lateral wall mantle layer relationship: part_of UBERON:0009582 {source="EMAPA"} ! spinal cord lateral wall xref: EMAPA:17580 ! mantle layer of lateral wall of spinal cord of central nervous system of nervous system of organ system xref: VHOG:0000911 ! mantle layer lateral wall spinal cord synonym: "mantle layer lateral wall spinal cord" EXACT [VHOG:0000911] [Term] id: UBERON:0013159 name: epithalamus mantle layer is_a: UBERON:0004022 ! embryonic neuroepithelium is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: develops_from UBERON:0009580 ! diencephalon mantle layer relationship: part_of UBERON:0001899 {source="EHDAA2"} ! epithalamus synonym: "mantle layer epithalamus" EXACT [VHOG:0000913] synonym: "mantle layer of epithalamus" EXACT [] xref: EHDAA2:0000449 ! epithalamus mantle layer xref: EMAPA:17533 ! mantle layer xref: VHOG:0000913 ! mantle layer epithalamus xref: EHDAA:5435 ! mantle layer [Term] id: UBERON:0013160 name: epithalamus ventricular layer is_a: UBERON:0004022 ! embryonic neuroepithelium relationship: part_of UBERON:0001899 {source="EHDAA2"} ! epithalamus synonym: "ventricular layer epithalamus" EXACT [VHOG:0000884] synonym: "ventricular layer of epithalamus" EXACT [] xref: EHDAA2:0000450 ! epithalamus ventricular layer xref: EMAPA:17535 ! ventricular layer xref: EHDAA:5437 ! ventricular layer xref: VHOG:0000884 ! ventricular layer epithalamus [Term] id: UBERON:0005882 ! alar plate name: alar plate def: "the mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses." [MP:0009692, Wikipedia:Alar_plate] synonym: "alar plate of neural tube" EXACT [] synonym: "dorsal part of neural tube" RELATED [] synonym: "alar lamina" RELATED [Wikipedia:Alar_lamina] synonym: "lamina dorsolateralis" RELATED LATIN [Wikipedia:Alar_plate] synonym: "lamina alaris" RELATED LATIN [Wikipedia:Alar_plate] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0004061 ! neural tube mantle layer relationship: dorsal_to UBERON:0005478 ! sulcus limitans of neural tube xref: http://upload.wikimedia.org/wikipedia/commons/2/29/Gray646.png [Term] id: UBERON:0004063 name: spinal cord alar plate def: "the region of the mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses; the alar plate develops into the dorsal horn in the grey matter of the spinal cord" [MP:0009692] synonym: "spinal cord alar column" EXACT [MP:0009692] synonym: "spinal cord alar lamina" EXACT [MP:0009692] comment: TODO - merge with UBERON:0003054 roof plate? is_a: UBERON:0005882 ! alar plate relationship: part_of UBERON:0006241 ! future spinal cord xref: EMAPA:17581 ! alar columns xref: EMAPA:17149 ! alar columns xref: VHOG:0000899 ! alar column spinal cord synonym: "alar column spinal cord" EXACT [VHOG:0000899] [Term] id: UBERON:0004064 ! basal plate name: neural tube basal plate def: "the region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons. the region of the neural tube ventral to the sulcus limitans. It extends from the rostral mesencephalon to the end of the spinal cord and contains primarily motor neurons, whereas neurons found in the alar plate are primarily associated with sensory functions. The cell types of the basal plate include lower motor neurons and four types of interneuron. Initially the left and right sides of the basal plate are continuous, but during neurulation they become separated by the floor plate, a derivative of the notochord[WP]." [MP:0009693, Wikipedia:Basal_plate_(neural_tube)] synonym: "basal plate" EXACT [] synonym: "ventral part of neural tube" RELATED [] synonym: "spinal cord basal plate" NARROW [MP:0009693] synonym: "basal plate of neural tube" EXACT [Wikipedia:Basal_plate_(neural_tube)] xref: EFO:0001904 ! basal plate is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0004061 ! neural tube mantle layer relationship: ventral_to UBERON:0005478 ! sulcus limitans of neural tube relationship: induced_by UBERON:0002328 {source="Swenson", gene="Shh"} ! notochord xref: ncithesaurus:Basal_Plate ! Basal Plate xref: AAO:0010561 ! basal plate xref: UMLS:C1511061 [Term] id: UBERON:0010286 name: midbrain neural tube def: "Portion of neural tube that gives rise to the midbrain." [ZFA:0007039] xref: TAO:0007039 ! midbrain neural tube is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0003080 {source="ZFA"} ! anterior neural tube xref: ZFA:0007039 ! midbrain neural tube [Term] id: UBERON:0010285 ! midbrain basal plate name: midbrain basal plate def: "Portion of tissue that is dorsolateral to the floor plate and part of the midbrain." [ZFA:0000761] is_a: UBERON:0002020 {source="EHDAA2"} ! gray matter of neuraxis relationship: part_of UBERON:0010286 {source="ZFA"} ! midbrain neural tube relationship: part_of UBERON:0009581 {source="EHDAA2"} ! midbrain mantle layer xref: EHDAA2:0004375 ! midbrain basal plate xref: ZFA:0000761 ! basal plate midbrain region xref: TAO:0000761 ! basal plate midbrain synonym: "basal plate midbrain" EXACT [TAO:0000761] xref: EFO:0003567 ! basal plate midbrain region [Term] id: UBERON:0005239 name: basal plate metencephalon synonym: "metencephalon basal plate" EXACT [EHDAA2:0001154] xref: VHOG:0000320 xref: EHDAA2:0001154 ! metencephalon basal plate xref: EMAPA:17078 ! basal plate of lateral wall of metencephalon is_a: UBERON:0004064 ! basal plate property_value: external_definition "The ventral half of the developing neural tube that is the metencephalon. [Chordate_evolution_and_the_origin_of_craniates:_An_old_brain_in_a_new_head._AnaT_Rec_(New_Anat)_(2000)_261(3):_111-125, See_Butler_AB][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000320", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005240 name: basal plate medulla oblongata xref: VHOG:0000324 xref: EHDAA2:0001093 ! medulla oblongata basal plate synonym: "medulla oblongata basal plate" EXACT [EHDAA2:0001093] xref: EMAPA:17557 ! basal plate of lateral wall of medulla oblongata is_a: UBERON:0004064 ! basal plate property_value: external_definition "The ventral half of the developing neural tube that is the medulla oblongata. [Chordate_evolution_and_the_origin_of_craniates:_An_old_brain_in_a_new_head._AnaT_Rec_(New_Anat)_(2000)_261(3):_111-125, See_Butler_AB][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000324", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0009579 name: myelencephalon basal plate comment: todo - check EHDAA2 post-CNS-revision xref: VHOG:0000322 xref: EHDAA2:0000646 ! future myelencephalon basal plate synonym: "future myelencephalon basal plate" EXACT [EHDAA2:0000646] xref: EMAPA:17088 ! basal plate of lateral wall of myelencephalon is_a: UBERON:0004064 ! basal plate synonym: "basal plate myelencephalon" EXACT [VHOG:0000322] property_value: external_definition "The ventral half of the developing neural tube that is the myelencephalon. [Chordate_evolution_and_the_origin_of_craniates:_An_old_brain_in_a_new_head._AnaT_Rec_(New_Anat)_(2000)_261(3):_111-125, See_Butler_AB][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000322", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003054 name: roof plate def: "a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells." [GO:0021509, PMID:15378040] comment: TODO - Note that although this is classically defined as being located on the neural tube, in many AOs the roof plate continues post-embryonically after the neural tube has ceased to exist. Consider 'roof plate of neural tube'. TODO - alar plate vs roof plate subset: uberon_slim subset: vertebrate_core synonym: "alar plate" RELATED [Wikipedia:Roof_plate] synonym: "roofplate" EXACT [] xref: ZFA:0007058 ! roof plate is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001049 ! neural tube xref: AAO:0011097 ! roof plate xref: TAO:0007058 ! roof plate property_value: external_definition "Multi-tissue structure that is the dorsal-most aspect of the devleloping neural tube.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0007058", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005724 name: roof plate spinal cord region alt_id: UBERON:0005246 xref: TAO:0001177 ! roof plate spinal cord xref: XAO:0000022 ! roof plate xref: ZFA:0001177 ! roof plate spinal cord region xref: VHOG:0000777 intersection_of: UBERON:0000479 ! portion of tissue intersection_of: part_of UBERON:0003054 ! roof plate intersection_of: part_of UBERON:0002240 ! spinal cord synonym: "roof plate spinal cord" EXACT [VHOG:0000777] synonym: "roofplate spinal cord" RELATED [VHOG:0000777] synonym: "spinal cord roof" RELATED [VHOG:0000777] property_value: external_definition "Roof plate that is part of the spinal cord. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000777", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} def: "A tissue that is part of a spinal cord and is part of a roof plate." [OBOL:automatic] [Term] id: UBERON:0003056 name: pre-chordal neural plate def: "The portion of neural plate anterior to the mid-hindbrain junction." [XB:curator] comment: This class was created automatically from a combination of ontologies synonym: "anterior neural plate" RELATED [] xref: XAO:0000045 ! pre-chordal neural plate xref: ZFA:0007016 ! anterior neural plate xref: VHOG:0001200 ! anterior neural plate is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0003075 ! neural plate relationship: anterior_to UBERON:0009774 ! embryonic midbrain hindbrain boundary xref: AAO:0011084 ! pre-chordal neural plate xref: TAO:0007016 ! anterior neural plate property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001200", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003057 name: chordal neural plate def: "The portion of neural plate posterior to the mid-hindbrain junction." [XB:curator] comment: This class was created automatically from a combination of ontologies synonym: "posterior neural plate" RELATED [] xref: XAO:0000046 ! chordal neural plate xref: ZFA:0007017 ! posterior neural plate xref: VHOG:0001201 ! posterior neural plate is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0003075 ! neural plate relationship: posterior_to UBERON:0009774 ! embryonic midbrain hindbrain boundary xref: TAO:0007017 ! posterior neural plate property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001201", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003058 name: hypochord def: "The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta[GO]. near metamorphosis the hypochord fuses to the coccyx, thereby forming the urostyle[AAO]" [ISBN:0815318960, PMID:10648245, GO:0055016, AAO:0000733] comment: Unlike in frogs and axolotl, the hypochord does not appear to be endodermally derived[ZFA] subset: dubious_grouping synonym: "subnotochordal rod" EXACT [GO:0055016, PMID:10648245] xref: AAO:0000733 ! hypochord xref: VHOG:0000081 ! hypochord xref: TAO:0000031 ! hypochord xref: XAO:0000056 ! hypochord xref: ZFA:0000031 ! hypochord xref: EFO:0003475 ! hypochord is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0000925 {source="XAO"} ! endoderm property_value: external_definition "Unsegmented ventral structure in the caudal region of anuran larvae; near metamorphosis the hypochord fuses to the coccyx, thereby forming the urostyle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000733", date_retrieved="2012-06-20", source="AAO:Pugener_2002"} property_value: external_definition "A transient rod-like structure which is endodermally derived and located immediately ventral to the notochord. The hypochord is thought to play a role in positioning the dorsal aorta. Eriksson and Lofberg, 2000.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000031", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "In other words, we identified variations in gene expression patterns that may contribute to a molecular basis of evolutionary variation of axial structures between Teleostei and Mammalia in the determination of body axis. As already mentioned, one such difference is illustrated by the hypochord present in lower vertebrates but absent in higher animals. Perhaps, Tbx-b and Tbx-c are involved in the mechanisms underlying the formation of this organ that were lost during later evolution leading to the disappearance of the hypochord itself, similarly to other organs, such as the lateral line.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000081", ontology="VHOG", source="PMID:11548409 Korzh VP\, T-box genes and developmental decisions that cells make. Russian Journal of Developmental Biology (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003106 name: urostyle def: "In teleosts: Anatomical cluster that is the result of fusion of preural centrum 1 with one or more adjacent ural centra[AAO]; Rodlike caudal bony structure unique to anurans that lies within a compartment formed by the elongated, anteriorly oriented pelvic girdle. The urostyle is formed by the fusion of the coccyx and the hypochord[AAO]." [TAO:0000158, AAO:0000732] comment: In zebrafish, it is composed of preural vertebra 1 and ural centra 1 and 2. The number of ural centra that become fused with preural centrum 1 varies among teleost subgroups. Because of varying developmental origins the urostyle may not be homologous across species.[TAO]. Grouping with AAO dubious subset: uberon_slim synonym: "compound centrum" RELATED [] synonym: "last vertebra" RELATED [] synonym: "ultimate vertebra" RELATED [] xref: AAO:0000732 ! urostyle xref: TAO:0000158 ! urostyle xref: XAO:0003080 ! urostyle xref: ZFA:0000158 ! urostyle is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0002090 ! postcranial axial skeleton property_value: external_definition "Rodlike caudal bony structure unique to anurans that lies within a compartment formed by the elongated, anteriorly oriented pelvic girdle. The urostyle is formed by the fusion of the coccyx and the hypochord.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000732", date_retrieved="2012-06-20", source="AAO:Pugener_2002", source="AAO:Pugener_and_Maglia_2008"} property_value: external_definition "Anatomical cluster that is the result of fusion of preural centrum 1 with one or more adjacent ural centra.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000158", date_retrieved="2012-08-14", source="TAO:wd", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of caudal fin skeleton (VSAO:0000167)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000158", date_retrieved="2012-08-14"} synonym: "compound caudal centrum" RELATED [TAO:0000158] synonym: "compound terminal centrum" RELATED [TAO:0000158] synonym: "compound terminal vertebra" RELATED [TAO:0000158] synonym: "terminal centrum" RELATED [TAO:0000158] property_value: external_comment "In zebrafish, it is composed of preural vertebra 1 and ural centra 1 and 2. The number of ural centra that become fused with preural centrum 1 varies among teleost subgroups. Because of varying developmental origins the urostyle may not be homologous across species.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000158", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0005727 name: obsolete somitomere def: "Obsoleted definition: In the developing vertebrate embryo, the somitomeres are loose masses of paraxial mesoderm derived cells that form along each side of the neural tube towards the end of the third gestational week. The approximately 50 pairs of somitomeres begin developing in the cranial (head) region, continuing in a caudal (tail) direction until the end of week four[WP]." [Wikipedia:Somitomere] comment: Around the same time that experimental embryology in avian systems was most productive in the context of vertebrate head development, researchers examining embryonic head morphology with the scanning electron microscope introduced the idea of cephalic “somitomeres”. By removing the surface ectoderm from the head, they reported that the paraxial mesoderm was organized into pseudosegmental units resembling incompletely differentiated somites, which they called somitomeres (Meier 1979; Jacobson 1988, 1993; Jacobson and Meier 1984). Since then, however, there has been no clear evidence for somitomeres. It remains unclear how they relate to the epithelial cysts in the head mesoderm - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895339/] synonym: "somatomere" RELATED [Wikipedia:Somitomere] xref: FMA:85523 ! somitomere is_obsolete: true [Term] id: UBERON:0007282 name: presumptive segmental plate xref: ZFA:0000053 ! presumptive segmental plate xref: EFO:0003421 ! presumptive segmental plate intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0003059 ! presomitic mesoderm relationship: develops_from UBERON:0009618 {source="EDHAA2", consistent_with="UBERONREF:0000002"} ! trunk paraxial mesoderm xref: TAO:0000053 ! presumptive segmental plate def: "A presumptive structure that develops_into a presomitic mesoderm." [OBOL:automatic] [Term] id: UBERON:0003059 name: presomitic mesoderm def: "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995." [ZFIN:curator] synonym: "PSM" RELATED [] synonym: "segmental plate" EXACT [] synonym: "somitogenic mesoderm" RELATED [] synonym: "presumptive somite mesoderm" RELATED [] synonym: "unsegmented paraxial mesoderm" EXACT [UBERON:cjm] xref: VHOG:0000559 ! presomitic mesoderm xref: TAO:0000279 ! segmental plate xref: XAO:0000057 ! presomitic mesoderm xref: ZFA:0000279 ! segmental plate xref: EFO:0001982 ! presomitic mesoderm xref: AAO:0011086 ! presomitic mesoderm is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0003077 ! paraxial mesoderm relationship: develops_from UBERON:0007282 {evidence="definitional"} ! presumptive segmental plate property_value: external_definition "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000279", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "unsegmented mesenchyme" RELATED [VHOG:0000559] property_value: homology_notes "It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG]" xsd:string {external_class="VHOG:0000559", ontology="VHOG", source="DOI:10.1006/dbio.2001.0460 Schubert M\, Holland LZ\, Dale Stokes M and Holland ND\, Three Amphoxius Wnt Genes (AmphiWnt3\, AmphiWnt5\, and AmphiWnt6) Associated with the Tail Bud: the Evolution of Somitogenesis in Chordates. Developmental Biology (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0002329 name: somite def: "Somites are spheres of epithelial cells that form sequentially along the anterior–posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm." [Wikipedia:Somite, doi:10.1111/j.1439-0426.2012.01987.x] comment: Editor notes: currently classified as an epithelial vesicle, consistent with EHDAA2 and UBERONREF:0000002. Consider making "somitic mesoderm" a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk // When the somite becomes segmented from the segmental plate, it is composed of an epithelial sac enclosing mesenchymal somitocoel cells. Thereafter the somite differentiates into two parts, the ventro-medial mesenchymal sclerotome and the dorso-lateral epithelial dermomyotome. This change in the epithelial somite depends on surrounding tissue [PMID:15906248] subset: uberon_slim subset: vertebrate_core synonym: "somites" RELATED PLURAL [] synonym: "mesodermal cluster" EXACT [GO:0001756] synonym: "somitic mesoderm" RELATED [] synonym: "epithelial somite" RELATED [UBERONREF:0000002] xref: EHDAA:366 ! somite xref: EHDAA:699 ! somite xref: FMA:85522 ! Somite xref: GAID:1306 ! somite xref: VHOG:0000191 ! somite xref: MAT:0000068 ! somite xref: MIAA:0000068 ! somite xref: TAO:0000155 ! somite xref: XAO:0000058 ! somite xref: ZFA:0000155 ! somite xref: ncithesaurus:Somite ! Somite xref: BTO:0001558 ! somite xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png xref: MESH:A16.254.425.660.750 ! somite xref: EHDAA2:0003436 ! somite xref: AEO:0001015 ! somite is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle relationship: develops_from UBERON:0003059 {source="ZFA"} ! presomitic mesoderm relationship: only_in_taxon NCBITaxon:7711 {source="GOTAX:0000352"} ! Chordata relationship: never_in_taxon NCBITaxon:7712 {source="PMID:17237766"} ! Tunicata xref: AAO:0010569 ! somite synonym: "somitus" RELATED LATIN [Wikipedia:Somite] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png property_value: external_definition "Post-cranial axial segments which form sclerotome and dermomyotome.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010569", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship type change: part_of paraxial mesoderm (AAO:0010568) CHANGED TO: develops_from paraxial mesoderm (UBERON:0003077)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010569", date_retrieved="2012-06-20"} property_value: external_definition "Undifferentiated mesodermal components of early trunk or tail segments or metameres, derived from paraxial mesoderm; forms myotomes, sclerotomes and perhaps dermatomes. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000155", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from paraxial mesenchyme (TAO:0000942)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000155", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: OBO_REL:part_of trunk (TAO:0001115) CHANGED TO: develops_from trunk (UBERON:0002100)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000155", date_retrieved="2012-08-14"} property_value: homology_notes " (...) cephalocordates and craniates belong to a group known as Somitichordata. Somitichordate synapomorphies include (1) somites (...) (reference 1); The idea that the last common ancestor of bilaterian animals (Urbilateria) was segmented has been raised recently on evidence coming from comparative molecular embryology (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000191", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.40\, DOI:10.1093/icb/43.1.137 Balavoine G\, Adoutte A\, The segmented urbilateria: a testable scenario. Integrative and Comparative Biology (2003)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "somitic" xsd:string xref: UMLS:C0376449 [Term] id: UBERON:0004290 ! dermomyotome name: dermomyotome def: "The bilaminar epithelium formed from the myotome and dermatome." [AEO:0000214] xref: ZFA:0001513 ! dermomyotome xref: VHOG:0000676 ! dermomyotome xref: EHDAA2:0003259 ! dermomyotome xref: ncithesaurus:Dermomyotome ! Dermomyotome is_a: UBERON:0000486 {source="EHDAA2"} ! multilaminar epithelium relationship: develops_from UBERON:0002329 {source="ZFA", source="EHDAA2"} ! somite relationship: part_of UBERON:0000926 ! mesoderm xref: AAO:0010572 ! dermomyotome xref: TAO:0001513 ! dermomyotome xref: AEO:0000214 ! dermomyotome property_value: external_definition "Portion of somites that gives rise to dermis and muscles.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010572", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001513", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "dermamyotome" RELATED [VHOG:0000676] synonym: "dermomyotomes" RELATED PLURAL [VHOG:0000676] property_value: homology_notes "Thus, representatives of the agnathan vertebrates, chondrichthyans, and sarcopterygians all have a layer of undifferentiated cells external to the embryonic myotome. In the amniotes, this external cell layer is the dermomyotome. The simplest interpretation of the similar position, morphology, and lack of myosin labeling is that a dermomyotome epithelium is a shared, ancestral vertebrate characteristic.[well established][VHOG]" xsd:string {external_class="VHOG:0000676", ontology="VHOG", source="DOI:10.1111/j.1525-142X.2006.05079.x Devoto SH\, Stoiber W\, Hammond CL\, Steinbacher P\, Haslett JR\, Barresi MJF\, Patterson SE\, Adiarte EG and Hughes SM\, Generality of vertebrate developmental patterns: evidence for a dermomyotome in fish. Evolution and Development (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1511786 property_value: external_definition "Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis. Within the dermomyotome there is also a medio-lateral difference. The central region makes dermis, the mesenchymal connective tissue of the back skin. The medial region (closest to neural tube) makes epaxial muscle, and the lateral region (furthest from neural tube) makes hypaxial muscle[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768]." xsd:string {source="http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768"} [Term] id: UBERON:0004016 ! dermatome name: dermatome def: "the mesoderm that is derived from the somite that is fated to become the dermis[MP]" [MP:0003940, Wikipedia:Dermatomal_mesenchyme] comment: Not to be confused with 'dermatome segment of skin'. synonym: "cutis plate" EXACT [Wikipedia:Cutis_plate] synonym: "dermatomal mesenchyme" EXACT [Wikipedia:Cutis_plate] xref: XAO:0000220 ! dermatome xref: EHDAA:1719 ! dermatome xref: EHDAA:1725 ! dermatome xref: EHDAA:1731 ! dermatome xref: EHDAA:1737 ! dermatome xref: ncithesaurus:Dermatome ! Dermatome is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0004290 {source="EHDAA2"} ! dermomyotome relationship: part_of UBERON:0000926 ! mesoderm xref: AAO:0011028 ! dermatome xref: AEO:0001017 ! dermatome xref: EHDAA2:0003428 ! dermatome synonym: "mesenchyma dermatomiale" RELATED LATIN [Wikipedia:Dermatomal_mesenchyme] xref: http://upload.wikimedia.org/wikipedia/commons/f/f3/Gray64.png xref: UMLS:C0180383 [Term] id: UBERON:0003082 ! myotome name: myotome def: "A group of tissues formed from somites that develop into the body wall muscle[WP]. Somitic compartment that is a precursor of muscle. mesoderm that is derived from the somite that is fated to become the musculature[MP]. Portion of the somites giving rise to body wall muscle masses[ZFA]" [PMID:17313522, Wikipedia:Myotome, ZFIN:curator, MP:0003939] comment: Editors note: The term "myotome" is also used to describe the muscles served by a single nerve root / spinal segment - consider adding new class. subset: uberon_slim subset: vertebrate_core synonym: "myomere" RELATED [] synonym: "myotomes" RELATED [] synonym: "myotome region" RELATED [] synonym: "muscle plate" RELATED [] xref: BTO:0000742 xref: EHDAA:1721 ! myotome xref: EHDAA:1727 ! myotome xref: EHDAA:1733 ! myotome xref: EHDAA:1739 ! myotome xref: VHOG:0001244 ! myotome xref: TAO:0001056 ! myotome xref: XAO:0000315 ! myotome xref: ZFA:0001056 ! myotome xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/96/Gray65.png/200px-Gray65.png xref: EHDAA2:0003431 ! myotome xref: AEO:0001018 ! myotome is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0004290 {source="EHDAA2"} ! dermomyotome relationship: part_of UBERON:0000926 ! mesoderm xref: AAO:0011067 ! myotome xref: SCTID:344535001 ! Entire myotome xref: ncithesaurus:Myotome_Region ! Myotome Region synonym: "myotomus" RELATED LATIN [Wikipedia:Myotome] xref: http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png property_value: external_definition "Portion of the somites giving rise to body wall muscle masses. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001056", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "myomeres" EXACT PLURAL [TAO:0001056] property_value: homology_notes "In all vertebrates, the skeletal muscle of the body axis is chiefly derived from an early embryonic compartment, known as the myotome.[well established][VHOG]" xsd:string {external_class="VHOG:0001244", ontology="VHOG", source="DOI:10.1038/sj.embor.embor920 Hollway GE\, Currie PD\, Myotome meanderings. Cellular morphogenesis and the making of muscle. EMBO Rep.(2003)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1513802 [Term] id: UBERON:0010963 name: trunk and cervical myotome group comment: isa row in EHDAA2 is_a: UBERON:0003082 ! myotome relationship: part_of UBERON:0005256 {source="EHDAA2"} ! trunk mesenchyme xref: EHDAA2:0003425 ! trunk and cervical myotome group [Term] id: UBERON:0003089 ! sclerotome name: sclerotome def: "Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]." [Wikipedia:Sclerotome, XB:curator] comment: AO notes: part_of somite in XAO subset: uberon_slim subset: vertebrate_core xref: VHOG:0000680 ! sclerotome xref: TAO:0001080 ! sclerotome xref: XAO:0000397 ! sclerotome xref: ZFA:0001080 ! sclerotome xref: ncithesaurus:Sclerotome ! Sclerotome xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/96/Gray65.png/200px-Gray65.png is_a: UBERON:0005856 {source="EHDAA2"} ! mesenchymal condensation is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: develops_from UBERON:0002329 {source="ZFA"} ! somite xref: AAO:0010571 ! sclerotome xref: EHDAA2:0003439 ! sclerotome xref: AEO:0000212 ! sclerotome synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] xref: http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png property_value: external_definition "Skeletogenic portion of somites.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010571", date_retrieved="2012-06-20", source="AAO:EJS"} synonym: "sclerotomes" EXACT PLURAL [TAO:0001080] property_value: homology_notes "The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG]" xsd:string {external_class="VHOG:0000680", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0183176 [Term] id: UBERON:0003061 name: blood island def: "Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]." [Wikipedia:Blood_island_of_umbilical_vesicle] comment: AO notes: EHDAA2 distinguishes 3 types, but does not have a superclass. The VHOG class may refer to yolk sac subset: uberon_slim subset: vertebrate_core synonym: "blood islands" EXACT PLURAL [] synonym: "caudal hematopoietic tissue" RELATED [] synonym: "posterior blood island" RELATED [] synonym: "posterior ICM" RELATED [] synonym: "VBI" RELATED [] synonym: "ventral blood island" RELATED [] synonym: "ventral lateral plate mesoderm" BROAD [] xref: VHOG:0000085 ! blood island xref: TAO:0000094 ! blood island xref: XAO:0000067 ! blood island xref: ZFA:0000094 ! blood island xref: ncithesaurus:Blood_Island ! Blood Island xref: EFO:0003489 ! blood island xref: TE:E5.11.2.0.0.0.4 xref: EHDAA:207 xref: AAO:0011006 ! blood island is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0003081 ! lateral plate mesoderm relationship: develops_into UBERON:0002390 ! hematopoietic system relationship: site_of GO:0001525 {source="ISBN10:0073040584"} ! angiogenesis relationship: site_of GO:0030097 {source="ISBN10:0073040584"} ! hemopoiesis property_value: external_definition "Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011006", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Nests of developing blood cells arising late in the segmentation period from the intermediate mass, and located in the anterior-ventral tail, just posterior to the yolk extension. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000094", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of intermediate cell mass of mesoderm (TAO:0000033)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000094", date_retrieved="2012-08-14"} property_value: homology_notes "Small clusters of mesodermal cells called blood islands mark the embryonic debut of the cardiovascular system (in vertebrates) (reference 1); In birds and mammals, primitive hemangioblasts are extraembryonic, populating the yolk sac as the so-called blood islands (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000085", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.450\, DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V\, Blood cells and blood cell development in the animal kingdom. Annual Review of Cell and Developmental Biology (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1511224 [Term] id: UBERON:0003304 alt_id: UBERON:0003305 name: mesoderm blood island comment: in EHDAA2, gives rise to blood and dorsal aorta synonym: "mesoderm blood islands" EXACT PLURAL [EHDAA2:0003241] synonym: "mesenchyme blood island" RELATED [OBOL:automatic] xref: EHDAA:170 ! blood island xref: EMAPA:16115 ! blood island of mesoderm of yolk sac (also: UBERON:0011919 'yolk sac blood island') xref: EMAPA:16268 ! blood island of mesenchyme of yolk sac (also: UBERON:0011919 'yolk sac blood island') is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle intersection_of: UBERON:0003061 ! blood island intersection_of: part_of UBERON:0000926 ! mesoderm relationship: part_of UBERON:0007798 {source="EHDAA2"} ! vascular system relationship: develops_from UBERON:0000926 {source="EHDAA2"} ! mesoderm xref: EHDAA2:0003241 ! mesoderm blood islands def: "A blood island that is part of a mesoderm." [OBOL:automatic] [Term] id: UBERON:0011919 name: yolk sac blood island def: "masses of developing blood cells attached to endothelium in the yolk sac" [MP:0011204] synonym: "yolk sac blood islands" EXACT [EHDAA2:0000177] synonym: "visceral yolk sac blood island" EXACT [MP:0011204] relationship: develops_from UBERON:0003316 {source="EHDAA2"} ! mesenchyme of yolk sac intersection_of: UBERON:0003061 ! blood island intersection_of: part_of UBERON:0003316 ! mesenchyme of yolk sac xref: EHDAA2:0000177 ! yolk sac blood islands xref: EMAPA:16268 ! blood island of mesenchyme of yolk sac (also: UBERON:0003304 'mesoderm blood island') xref: EMAPA:16115 ! blood island of mesoderm of yolk sac (also: UBERON:0003304 'mesoderm blood island') [Term] id: UBERON:0011921 name: connecting stalk blood islands comment: AO notes: in EHDAA2 gives rise to connecting stalk blood vessels and extraembryonic umbilical vessels synonym: "blood island of umbilical vesicle" EXACT [Wikipedia:Blood_island] synonym: "insula sanguinea vesiculae umbilicalis" EXACT [Wikipedia:Blood_island] is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle relationship: develops_from UBERON:0005667 {source="EHDAA2"} ! connecting stalk mesoderm relationship: part_of UBERON:0002331 {source="EHDAA2"} ! umbilical cord xref: EHDAA2:0003242 ! connecting stalk blood islands [Term] id: UBERON:0007807 name: connecting stalk blood vessel xref: EHDAA2:0000313 ! connecting stalk blood vessels synonym: "connecting stalk blood vessels" EXACT PLURAL [EHDAA2:0000313] is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure relationship: part_of UBERON:0007806 ! connecting stalk relationship: develops_from UBERON:0011921 {source="EHDAA2"} ! connecting stalk blood islands [Term] id: UBERON:0007806 ! connecting stalk name: connecting stalk def: "A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord." [Medical_Dictionary:http://medical-dictionary.thefreedictionary.com/] comment: todo - this is currently defined as a bridge of mesoderm, but in EHDAA2 is extraembryonic structure split into mesoderm and blood vessels xref: BTO:0004705 ! connecting stalk is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure relationship: develops_from UBERON:0005728 {source="EHDAA2"} ! extraembryonic mesoderm xref: ncithesaurus:Connecting_Stalk ! Connecting Stalk xref: UMLS:C1516792 [Term] id: UBERON:0005667 name: connecting stalk mesoderm xref: EHDAA2:0000314 ! connecting stalk mesoderm is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure relationship: part_of UBERON:0007806 ! connecting stalk [Term] id: UBERON:0002331 name: umbilical cord def: "The connecting cord from the developing embryo or fetus to the placenta. During prenatal development, the umbilical cord comes from the same zygote as the fetus and (in humans) normally contains two arteries (the umbilical arteries) and one vein (the umbilical vein), buried within Wharton's jelly. The umbilical vein supplies the fetus with oxygenated, nutrient-rich blood from the placenta. Conversely, the umbilical arteries return the deoxygenated, nutrient-depleted blood[WP]." [Wikipedia:Umbilical_cord] comment: See notes for connecting stalk subset: uberon_slim synonym: "connecting stalk" RELATED [] synonym: "birth cord" RELATED [Wikipedia:Umbilical_cord] synonym: "yolk stalk" RELATED [BTO:0001415] xref: FMA:85541 ! Umbilical cord xref: GAID:517 ! umbilical cord xref: MAT:0000280 ! umbilical cord xref: MIAA:0000280 ! umbilical cord xref: ncithesaurus:Umbilical_Cord ! Umbilical Cord xref: BTO:0001415 ! umbilical cord xref: EFO:0001415 ! umbilical cord xref: OpenCyc:Mx4rvyewDJwpEbGdrcN5Y29ycA ! umbilical cord xref: EHDAA2:0000312 ! connecting stalk xref: EMAPA:26115 ! umbilical cord xref: MESH:A16.254.789 ! umbilical cord xref: EHDAA:158 ! connecting stalk xref: EV:0100127 ! umbilical cord is_a: UBERON:0000478 ! extraembryonic structure relationship: develops_from UBERON:0007806 ! connecting stalk relationship: connects UBERON:0000922 ! embryo relationship: connects UBERON:0001987 ! placenta xref: SCTID:280644003 ! Entire umbilical cord synonym: "funiculus umbilicalis" RELATED LATIN [Wikipedia:Umbilical_cord] xref: http://upload.wikimedia.org/wikipedia/commons/f/f3/Umbilicalcord.jpg property_value: has_relational_adjective "umbilical" xsd:string xref: UMLS:C0041633 [Term] id: UBERON:0003065 name: ciliary marginal zone def: "Region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth. Wehman et al, 2005." [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "circumferential germinal zone" RELATED [] synonym: "CMZ" RELATED [] synonym: "peripheral growth zone" EXACT [ZFA:0001289] xref: VHOG:0000088 ! ciliary marginal zone xref: TAO:0001289 ! ciliary marginal zone xref: XAO:0000086 ! ciliary marginal zone xref: ZFA:0001289 ! ciliary marginal zone xref: EFO:0003668 ! ciliary marginal zone is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0000966 ! retina xref: AAO:0010342 ! ciliary marginal zone property_value: external_definition "Region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth. Wehman et al, 2005.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001289", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "The retina of all vertebrates develops via similar mechanisms. Toward the end of retinal histogenesis, proliferating progenitors and newly generated cells are confined to peripheral regions of the retina. In fish and amphibians, this region is maintained after embryonic development and becomes the CMZ (ciliary margin zone). A CMZ exists in birds but compared to that of fish and amphibians this region produces much less new retina as the globe of the eye expands postnatally. At least some of the molecular mechanisms that regulate the addition of new cells in this zone appear to have been conserved from fish to birds.[well established][VHOG]" xsd:string {external_class="VHOG:0000088", ontology="VHOG", source="DOI:10.1159/000057571 Reh TA\, Fischer AJ\, Stem cells in the vertebrate retina. Brain Behav Evol (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003067 name: dorsolateral placode def: "Lateral neurogenic placodes positioned dorsal of the epibranchial placodes." [ZFIN:curator] comment: The only remaining dorsolateral placode in land vertebrates is the otic/octaval placode synonym: "dorsolateral placodes" EXACT PLURAL [ZFA:0001310] xref: VHOG:0000103 ! dorsolateral placode xref: TAO:0001310 ! dorsolateral placode xref: XAO:0000187 ! dorsolateral placode xref: ZFA:0001310 ! dorsolateral placode is_a: UBERON:0009955 {source="NBK53175"} ! neurogenic placode relationship: dorsal_to UBERON:0003078 ! epibranchial placode property_value: homology_notes "In summary, the collective term 'placodes' refers to some rather different structures, probably with different evolutionary origins. Some sensory placodes (at least the otic and olfactory) may have homologues in basal chordates. Even if this is so, it is apparent that they were elaborated considerably during early vertebrate evolution. Epibranchial and dorsolateral placodes appear to be new; we infer that their origin depended on the evolution of specific inductive signals.[well established][VHOG]" xsd:string {external_class="VHOG:0000103", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005494 name: intermediate mesenchyme def: "." [https://sourceforge.net/tracker/?func=detail&aid=3515562&group_id=76834&atid=994726] subset: vertebrate_core xref: ZFA:0000990 ! intermediate mesenchyme xref: EHDAA2:0000871 ! intermediate mesenchyme xref: VHOG:0000261 ! intermediate mesenchyme xref: EHDAA:689 ! intermediate mesenchyme is_a: UBERON:0005256 {source="ZFA"} ! trunk mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0003064 ! intermediate mesoderm xref: TAO:0000990 ! intermediate mesenchyme [Term] id: UBERON:0003064 ! intermediate mesoderm name: intermediate mesoderm def: "The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:curators, Wikipedia:Intermediate_mesoderm] comment: note that all AOs differ in the relationship between this structure and the mesoderm; in ZFA it is a subclass (and this is implied by the GO definition and GO relationships), in AAO it is part of, and in EHDAA2 it develops from the mesoderm (but in EHDAA2 the naming convention is to use 'paraxial mesenchyme', rather than 'paraxial mesoderm'). subset: uberon_slim subset: vertebrate_core synonym: "IM" RELATED [] synonym: "intermediate mesenchyme" RELATED [UBERONREF:0000002] synonym: "intermediate plate mesoderm" RELATED [UBERON:cjm] xref: VHOG:0000087 ! intermediate mesoderm xref: TAO:0001206 ! intermediate mesoderm xref: XAO:0000085 ! intermediate mesoderm xref: ZFA:0001206 ! intermediate mesoderm xref: ncithesaurus:Intermediate_Mesoderm ! Intermediate Mesoderm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png xref: EMAPA:16178 ! intermediate mesoderm is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000926 {source="AAO"} ! mesoderm relationship: part_of UBERON:0005256 {source="EMAPA"} ! trunk mesenchyme relationship: develops_from UBERON:0000926 {source="XAO"} ! mesoderm relationship: adjacent_to UBERON:0003077 ! paraxial mesoderm relationship: adjacent_to UBERON:0003081 ! lateral plate mesoderm xref: AAO:0010575 ! intermediate mesoderm xref: SCTID:361476001 ! Intermediate mesoderm synonym: "mesenchyma intermedium" RELATED LATIN [Wikipedia:Intermediate_mesoderm] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png property_value: external_definition "Mesoderm between somite and lateral plate. Traditionally thought to give rise to the urogenital system.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010575", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "(...)the mesoderm of a developing vertebrate transitionally differentiates into the following sub-types: Chordamesoderm (also known as axial mesoderm) which later on gives rise to notochord in all chordates, Paraxial mesoderm, Intermediate mesoderm, Lateral plate mesoderm (reference 1); The mesoderm is present in Bilateria, therefore they are sometimes called triploblasts. Ectoderm and endoderm are usually organized as epithelial layers, while mesoderm can be epithelial or a compact, three-dimensional tissue.[well established][VHOG]" xsd:string {external_class="VHOG:0000087", ontology="VHOG", source="http://en.wikipedia.org/wiki/Mesoderm\, ISBN:978-0198566694 Schmidt-Rhaesa A\, The evolution of organ systems (2007) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1284010 [Term] id: UBERON:0003063 alt_id: UBERON:0004881 name: prechordal plate def: "a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells[GO]. Axial hypoblast located anterior to the chordamesoderm; the polster is its most anterior region[ZFA]. Uniquely thickened portion of the endoderm that is in contact with ectoderm immediately rostral to the cephalic tip of the notochord[WP]." [ZFIN:curator, Wikipedia:Prechordal_plate] comment: todo - check; developmental relationship to anterior hypoblast in ZFA? subset: uberon_slim subset: vertebrate_core synonym: "head mesenchyme" BROAD [XAO:0000079] synonym: "head mesoderm" BROAD [XAO:0000079] xref: EHDAA:181 ! prechordal plate xref: VHOG:0000086 ! prechordal plate xref: TAO:0000060 ! prechordal plate xref: XAO:0000079 ! prechordal plate xref: ZFA:0000060 ! prechordal plate xref: EHDAA2:0001493 ! prechordal plate is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003068 {source="ZFA"} ! axial mesoderm xref: AAO:0011085 ! prechordal plate property_value: external_definition "Axial hypoblast located anterior to the chorda mesoderm; the polster is its most anterior region. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000060", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: external_definition "Axial mesoderm that lies anterior to the notochord and that underlies the forebrain. [Amphioxus_goosecoid_and_the_evolution_of_the_head_organizer_and_prechordal_plate._Evolution_and_Development_(2008)_2(6):303-310, Neidert_AH, Panopoulou_G_and_Langeland_JA][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000086", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "There are two opposing models that can potentially explain the differences in gsc (goosecoid) expression between amphioxus and vertebrates. In one model, the vertebrate gsc expression pattern more closely resembles the common ancestral state and the amphioxus gsc expression pattern is a derivation associated with its unique morphology. (...) In an alternate model, the amphioxus gsc expression pattern most closely represents the common ancestral state and the vertebrate pattern is derived. This model suggests that the evolution of vertebrates was accompanied by the segregation of gsc expression, from a more general domain underlying the entire brain anlage to a distinct forebrain organizer domain and subsequent prechordal plate. We feel this second model is more parsimonious than the first model in that what would be novel anterior gsc expression in vertebrates directly correlates with a novel vertebrate anterior structure, the prechordal plate.[well established][VHOG]" xsd:string {external_class="VHOG:0000086", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00073.x Neidert AH\, Panopoulou G and Langeland JA\, Amphioxus goosecoid and the evolution of the head organizer and prechordal plate. Evolution and Development (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005253 name: head mesenchyme def: "Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells." [ISBN:0683400088, MP:0011260] subset: vertebrate_core synonym: "cephalic mesenchyme" EXACT [MP:0011260] xref: VHOG:0000332 xref: ZFA:0000113 ! head mesenchyme xref: EMAPA:16098 ! head mesenchyme xref: EMAPA:16269 ! head mesenchyme xref: EHDAA2:0000732 ! head mesenchyme xref: EHDAA:179 ! head mesenchyme xref: EFO:0003492 ! head mesenchyme is_a: UBERON:0003104 {source="ZFA"} ! mesenchyme relationship: part_of UBERON:0000033 ! head xref: TAO:0000113 ! head mesenchyme property_value: external_definition "Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000113", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005280 ! head mesoderm name: obsolete head mesoderm synonym: "cranial mesoderm" EXACT [] is_obsolete: true replaced_by: UBERON:0006904 ! head mesenchyme from mesoderm [Term] id: UBERON:0004031 name: ectomesenchyme def: "mesenchymal cells derived from neural crest cells that contribute to development of the hard and soft tissue in the head and neck, including the branchial arches[MP]." [MP:0006302, Wikipedia:Ectomesenchyme] is_a: UBERON:0005253 ! head mesenchyme relationship: develops_from UBERON:0002342 ! neural crest property_value: external_definition "Ectomesenchyme has similar properties to mesenchyme. The major difference is that ectomesenchyme is usually considered to arise from neural crest cells, which are a critical group of cells that form in the cranial region during early vertebrate development. Thus, ectomesenchyme plays a critical role in the formation of the hard and soft tissues of the head and neck such as bones, muscles, teeth, and, most important, the branchial arches[Wikipedia:Ectomesenchyme]." xsd:string {source="Wikipedia:Ectomesenchyme"} [Term] id: UBERON:0006904 ! head mesenchyme from mesoderm name: head mesenchyme from mesoderm comment: Editor note: merged in 'head mesoderm' from XAO/AAO and EFO here. Partially implements UBERONREF:0000002 NC meeting scheme subset: vertebrate_core synonym: "head mesenchyme from head mesoderm" EXACT [EHDAA2:0001118] synonym: "mesenchyme derived from head mesoderm" EXACT [EHDAA:1057] synonym: "mesenchyme from head mesoderm" EXACT [] synonym: "head mesenchyme from mesoderm" EXACT [] synonym: "head mesenchyme derived from mesoderm" EXACT [] synonym: "cranial mesoderm" RELATED [UBERON:0005280] synonym: "head mesoderm" RELATED [AAO:0011051, UBERON:0005280] xref: ZFA:0000998 ! mesenchyme derived from head mesoderm xref: EHDAA2:0001118 ! head mesenchyme from head mesoderm xref: VHOG:0000185 ! mesenchyme derived from head mesoderm xref: EMAPA:16270 ! mesenchyme derived from head mesoderm xref: EMAPA:16099 ! mesenchyme derived from head mesoderm of head mesenchyme xref: EHDAA:655 ! mesenchyme derived from head mesoderm of head mesenchyme xref: EFO:0003603 ! mesenchyme derived from head mesoderm xref: XAO:0000053 ! head mesoderm xref: EFO:0003337 ! head mesoderm xref: AAO:0011051 ! head mesoderm intersection_of: UBERON:0005253 ! head mesenchyme intersection_of: develops_from UBERON:0000926 ! mesoderm is_a: UBERON:0005253 {source="ZFA"} ! head mesenchyme relationship: develops_from UBERON:0000926 {source="EHDAA2"} ! mesoderm relationship: develops_from UBERON:0003063 {source="EHDAA2", source="XAO"} ! prechordal plate xref: TAO:0000998 ! mesenchyme derived from head mesoderm def: "A head mesenchyme that develops_from a mesoderm." [OBOL:automatic] [Term] id: UBERON:0007213 name: mesenchyme derived from head neural crest subset: vertebrate_core synonym: "head mesenchyme from neural crest" EXACT [EHDAA2:0000735] synonym: "head mesenchyme from neural crest" EXACT [EHDAA2:0000735] synonym: "head mesenchyme from cranial neural crest" EXACT [] synonym: "head neural crest derived mesenchyme" EXACT [] xref: ZFA:0000787 ! mesenchyme derived from head neural crest xref: EHDAA2:0000735 ! head mesenchyme from neural crest xref: EMAPA:16271 ! mesenchyme derived from neural crest xref: EMAPA_RETIRED:16271 ! mesenchyme derived from neural crest xref: EMAPA:16169 ! mesenchyme derived from neural crest of head mesenchyme xref: EMAPA:16100 ! mesenchyme derived from neural-crest xref: EFO:0003572 ! mesenchyme derived from head neural crest is_a: UBERON:0005253 {source="ZFA"} ! head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0003099 ! cranial neural crest xref: TAO:0000787 ! mesenchyme derived from head neural crest def: "Mesenchyme that develops_from a cranial neural crest." [OBOL:automatic] [Term] id: UBERON:0007214 name: mesenchyme derived from trunk neural crest subset: vertebrate_core synonym: "trunk mesenchyme from neural crest" EXACT [EHDAA2:0002093] synonym: "trunk neural crest derived mesenchyme" EXACT [] xref: ZFA:0000999 ! mesenchyme derived from trunk neural crest xref: EHDAA2:0002093 ! trunk mesenchyme from neural crest xref: EMAPA:16182 ! mesenchyme derived from neural crest of trunk mesenchyme is_a: UBERON:0005256 ! trunk mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0003083 ! trunk neural crest xref: TAO:0000999 ! mesenchyme derived from trunk neural crest def: "Mesenchyme that develops_from a trunk neural crest." [OBOL:automatic] [Term] id: UBERON:0009617 ! head paraxial mesoderm name: head paraxial mesoderm def: "Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles." [PMID:21610022] synonym: "cephalic paraxial mesoderm" EXACT [UBERON:cjm] synonym: "cephalic paraxial mesoderm" EXACT [UBERON:cjm] synonym: "head paraxial mesenchyme" EXACT [EHDAA2:0000736] is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0003077 ! paraxial mesoderm relationship: part_of UBERON:0005253 {source="EHDAA2"} ! head mesenchyme relationship: develops_from UBERON:0000926 {source="EHDAA2"} ! mesoderm xref: EHDAA2:0000736 ! head paraxial mesenchyme xref: EMAPA:16171 ! paraxial mesenchyme of head mesenchyme xref: EHDAA:364 ! paraxial mesenchyme [Term] id: UBERON:0009618 ! trunk paraxial mesoderm name: trunk paraxial mesoderm synonym: "trunk paraxial mesenchyme" RELATED [] is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0003077 ! paraxial mesoderm relationship: part_of UBERON:0005256 {source="EHDAA2"} ! trunk mesenchyme relationship: develops_from UBERON:0000926 {source="EHDAA2"} ! mesoderm xref: EHDAA2:0002094 ! trunk and cervical paraxial mesenchyme synonym: "trunk and cervical paraxial mesenchyme" EXACT [EHDAA2:0002094] [Term] id: UBERON:0009620 name: tail bud paraxial mesoderm is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: part_of UBERON:0003077 ! paraxial mesoderm relationship: part_of UBERON:0002533 {source="EHDAA2"} ! tail bud relationship: develops_from UBERON:0009618 {source="EHDAA2"} ! trunk paraxial mesoderm xref: EHDAA2:0003239 ! tail bud paraxial mesoderm [Term] id: UBERON:0009891 name: facial mesenchyme synonym: "face mesenchyme" EXACT [] synonym: "mesenchyme of face" EXACT [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001456 ! face def: "Mesenchyme that is part of a face." [OBOL:automatic] [Term] id: UBERON:0011208 name: medial migration pathway NC-derived mesenchyme synonym: "medial migration pathway mesenchyme" EXACT [ZFA:0000786] synonym: "medial migration pathway" RELATED [] is_a: UBERON:0011210 ! migration pathway NC-derived mesenchyme xref: EHDAA2:0001075 ! medial migration pathway NC-derived mesenchyme xref: EHDAA:1747 ! medial migration pathway xref: EMAPA:16597 ! medial migration pathway xref: ZFA:0000786 ! medial migration pathway mesenchyme xref: TAO:0000786 ! medial migration pathway mesenchyme [Term] id: UBERON:0011209 name: lateral migration pathway NC-derived mesenchyme synonym: "lateral migration pathway mesenchyme" EXACT [ZFA:0000992] synonym: "lateral migration pathway" RELATED [] is_a: UBERON:0011210 ! migration pathway NC-derived mesenchyme xref: EHDAA2:0000915 ! lateral migration pathway NC-derived mesenchyme xref: EHDAA:1745 ! lateral migration pathway xref: EMAPA:16596 ! lateral migration pathway xref: TAO:0000992 ! lateral migration pathway mesenchyme xref: ZFA:0000992 ! lateral migration pathway mesenchyme [Term] id: UBERON:0011210 ! migration pathway NC-derived mesenchyme name: migration pathway NC-derived mesenchyme synonym: "migration pathway mesenchyme" EXACT [] synonym: "NC migration pathway" RELATED [] is_a: UBERON:0007530 {source="EHDAA2-abduced"} ! migrating mesenchyme population relationship: develops_from UBERON:0007214 {source="EHDAA2-abduced", source="ZFA-abduced"} ! mesenchyme derived from trunk neural crest relationship: part_of UBERON:0007214 {source="EHDAA2-abduced"} ! mesenchyme derived from trunk neural crest [Term] id: UBERON:0003070 name: trigeminal placode def: "The ectodermal rudiment of the trigeminal ganglion." [VHOG:0000109] comment: Fig9-5 of ISBN10:0471888893 calls this the profundus placode; XAO says 'profundal and the trigeminal ganglia are separate distally but fused at their proximal end...' synonym: "trigeminal V placode" EXACT [] synonym: "profundus placode" RELATED INCONSISTENT [ISBN10:0471888893] synonym: "profundus V placode" RELATED INCONSISTENT [ISBN10:0471888893] xref: VHOG:0000109 ! trigeminal placode xref: TAO:0000162 ! trigeminal placode xref: XAO:0000225 ! trigeminal placode xref: ZFA:0000162 ! trigeminal placode xref: EFO:0003433 ! trigeminal placode is_a: UBERON:0003067 {source="ISBN10:0471888893"} ! dorsolateral placode xref: EHDAA2:0004209 ! trigeminal placode property_value: external_definition "The ectodermal precursor of the trigeminal ganglion. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24.[XAO]" xsd:string {ontology="XAO"} property_value: external_definition "The ectodermal rudiment of the trigeminal ganglion, distinguishable during much of the segmentation period. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000162", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "The dorsolateral placodes (trigeminal and vestibular) develop from ectoderm lateral to the brain (...). In summary, the collective term 'placodes' refers to some rather different structures, probably with different evolutionary origins. Some sensory placodes (at least the otic and olfactory) may have homologues in basal chordates. Even if this is so, it is apparent that they were elaborated considerably during early vertebrate evolution. Epibranchial and dorsolateral placodes appear to be new; we infer that their origin depended on the evolution of specific inductive signals.[well established][VHOG]" xsd:string {external_class="VHOG:0000109", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003073 name: lens placode def: "A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]." [Wikipedia:Lens_placode, ZFIN:curator] comment: Classical transplantation experiments using amphibian embryos suggested that the optic vesicle is the source of lens-inducing signals sufficient to generate lens tissues in competent ectoderm (reviewed in Grainger et al., 1996). More recent findings suggest a multistep model for lens induction. There is now good evidence that lens specification occurs at the neurula stage, before the optic vesicle contact the surface ectoderm, and that neural crest cell migration in the frontonasal region is required to restrict the position of the lens placode (Bailey et al., 2006)[NBK53175] subset: uberon_slim subset: vertebrate_core xref: EHDAA:2908 ! lens placode xref: VHOG:0000166 ! lens placode xref: TAO:0000122 ! lens placode xref: XAO:0000240 ! lens placode xref: ZFA:0000122 ! lens placode xref: ncithesaurus:Lens_Placodes ! Lens Placodes xref: EHDAA2:0000982 ! lens placode xref: EMAPA:16672 ! lens placode xref: EFO:0003494 ! lens placode is_a: UBERON:0011814 {source="NBK53175"} ! non-neurogenic ectodermal placode is_a: UBERON:0002546 ! cranial placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: develops_into UBERON:0000965 ! lens relationship: part_of UBERON:0000076 ! external ectoderm relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye relationship: induced_by UBERON:0004128 ! optic vesicle xref: AAO:0011055 ! lens placode synonym: "placoda lentis" RELATED LATIN [Wikipedia:Lens_placode] xref: http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png property_value: external_definition "Ectodermal primordium of the lens of the eye. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000122", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {external_class="VHOG:0000166", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1517770 [Term] id: UBERON:0003078 ! epibranchial placode name: epibranchial placode def: "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia." [VHOG:0000117] comment: Epibranchial placodes-derived neurons innervate internal organs to transmit information such as heart rate, blood pressure, and visceral distension from the periphery to the central nervous system (Baker and Bronner-Fraser, 2001). From rostral to caudal the epibranchial placodes comprise the geniculate, petrosal, and nodose placodes, each associated in sequence with the first, second and third branchial clefts. Each placode contributes sensory neurons to cranial nerves VII (facial nerve), IX (glossopharyngeal nerve), and X (vagal nerve), respectively[NBK53175]. AO notes: in XAO this develops_from dorsolateral placode, but in NBK53175, this is a separate group synonym: "epibranchial placodes" EXACT PLURAL [ZFA:0001294] synonym: "ventrolateral placode" RELATED [ISBN10:0471888893] xref: VHOG:0000117 ! epibranchial placode xref: TAO:0001294 ! epibranchial placode xref: XAO:0000284 ! epibranchial placode xref: ZFA:0001294 ! epibranchial placode xref: EFO:0003455 ! epibranchial placode is_a: UBERON:0009955 {source="NBK53175", source="ZFA"} ! neurogenic placode is_a: UBERON:0007497 {source="EHDAA2-abduced"} ! developing epithelial placode relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000010 {source="ZFA"} ! peripheral nervous system relationship: develops_from UBERON:0000076 {source="EHDAA2-abduced"} ! external ectoderm relationship: part_of UBERON:0000010 ! peripheral nervous system xref: AAO:0011036 ! epibranchial placode property_value: external_definition "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. [Graham_A, The_development_and_evolution_of_the_pharyngeal_arches._J_Anat_(2001)_199:_133-141][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000117", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000117", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A\, The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009124 name: geniculate placode def: "Rostralmost epibranchial placode. Associated with 1st branchial cleft." [NBK:NBK53175] comment: Taxonomic equivalence to EHDAA2 class made on basis of shared development: gives rise to geniculate ganglion synonym: "facial VII placode" RELATED [] synonym: "hyoid placode" RELATED [ISBN10:0471888893] synonym: "hyoid VII placode" RELATED [ISBN10:0471888893] synonym: "facial placode" EXACT [ZFA:0001295] synonym: "facial epibranchial placode" EXACT [XAO:0004211] synonym: "epibranchial placode 1" EXACT [EHDAA2:0004206] xref: TAO:0001295 ! facial placode is_a: UBERON:0003078 {source="ZFA"} ! epibranchial placode xref: ZFA:0001295 ! facial placode xref: XAO:0004211 ! facial epibranchial placode xref: EHDAA2:0004206 ! epibranchial placode 1 [Term] id: UBERON:0009125 name: petrosal placode def: "Epibranchial placode between geniculate and nodose. Associated with 2nd branchial cleft." [NBK:NBK53175] comment: Taxonomic equivalence to EHDAA2 class made on basis of shared development: gives rise to glossopharyngeal ganglion synonym: "glossopharyngeal IX placode" EXACT [ISBN10:0471888893] synonym: "glossopharyngeal placode" EXACT [ZFA:0001296, ISBN10:0471888893] synonym: "glossopharyngeal epibranchial placode" EXACT [XAO:0004212] synonym: "epibranchial placode 2" EXACT [EHDAA2:0004207] xref: TAO:0001296 ! glossopharyngeal placode is_a: UBERON:0003078 {source="ZFA"} ! epibranchial placode xref: ZFA:0001296 ! glossopharyngeal placode xref: XAO:0004212 ! glossopharyngeal epibranchial placode xref: EHDAA2:0004207 ! epibranchial placode 2 [Term] id: UBERON:0009126 name: nodosal placode def: "Caudalmost epibranchial placode. Associated with 3rd branchial cleft." [NBK:NBK53175] comment: Taxonomic equivalence to EHDAA2 class made on basis of shared development: Gives rise to inferior vagus ganglion. Note that ZFA has 4 vagal placodes synonym: "vagal placode" RELATED [ISBN10:0471888893] synonym: "vagal X placode" RELATED [ISBN10:0471888893] synonym: "nodose placode" EXACT [XAO:0004213] synonym: "vagal epibranchial placode" EXACT [XAO:0004213] synonym: "epibranchial placode 3" EXACT [EHDAA2:0004208] is_a: UBERON:0003078 {source="NBK53175"} ! epibranchial placode xref: XAO:0004213 ! vagal epibranchial placode xref: EHDAA2:0004208 ! epibranchial placode 3 [Term] id: UBERON:0009127 name: epibranchial ganglion def: "Cranial ganglion which develops from an epibranchial placode." [ZFIN:curator, PMID:20133851] comment: Epibranchial ganglia orchestrate the development of the cranial neurogenic crest synonym: "epibranchial ganglia" EXACT PLURAL [ZFA:0001555] xref: TAO:0001555 ! epibranchial ganglion is_a: UBERON:0001714 {source="ZFA"} ! cranial ganglion intersection_of: UBERON:0001714 ! cranial ganglion intersection_of: develops_from UBERON:0003078 ! epibranchial placode relationship: develops_from UBERON:0003078 {source="NBK53175"} ! epibranchial placode xref: ZFA:0001555 ! epibranchial ganglion [Term] id: UBERON:0003079 name: floor plate def: "A ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage[GO]. A structure integral to the developing nervous system of vertebrate organisms. Located on the ventral midline of the embryonic neural tube, the floor plate is a specialized glial structure that spans the anteroposterior axis from the midbrain to the tail regions. It has been shown that the floor plate is conserved among vertebrates with homologous structures in invertebrates such as the fruit fly Drosophila and the nematode C. elegans. Functionally, the structure serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube[WP]." [GO:0021508, PMID:15738958, Wikipedia:Floor_plate] comment: Note that although this is classically defined as being located on the neural tube, in many AOs the floor plate continues post-embryonically after the neural tube has ceased to exist. Consider 'floor plate of neural tube'. subset: uberon_slim subset: vertebrate_core synonym: "floorplate" EXACT [] synonym: "bodenplatte" RELATED [BTO:0001720] synonym: "ventral plate" RELATED [BTO:0001720] xref: TAO:0000022 ! floor plate xref: ZFA:0000022 ! floor plate xref: BTO:0001720 ! floor plate xref: RETIRED_EHDAA2:0000545 ! floor plate xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/89/Gray642.png/200px-Gray642.png xref: EFO:0003473 ! floor plate is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001016 ! nervous system relationship: develops_from UBERON:0007286 {source="ZFA"} ! presumptive floor plate relationship: develops_from UBERON:0002328 {source="Wikipedia"} ! notochord relationship: secretes PR:000015557 ! spondin-1 xref: AAO:0011041 ! floor plate xref: http://upload.wikimedia.org/wikipedia/commons/8/89/Gray642.png property_value: external_definition "Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011041", date_retrieved="2012-06-20", source="GO:0021508", source="PMID:15738958"} synonym: "FP" RELATED [TAO:0000022] [Term] id: UBERON:0005723 name: floor plate spinal cord region alt_id: UBERON:0005247 subset: vertebrate_core synonym: "floorplate spinal cord" EXACT [ZFA:0000890] xref: TAO:0000890 ! floor plate spinal cord xref: XAO:0000306 ! floor plate xref: VHOG:0000787 ! floor plate spinal cord xref: EMAPA:17578 ! floor plate of spinal cord of central nervous system of nervous system of organ system xref: ZFA:0000890 ! floor plate spinal cord region intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0003079 ! floor plate intersection_of: part_of UBERON:0002240 ! spinal cord relationship: develops_from UBERON:0003306 ! floor plate of neural tube synonym: "floor plate spinal cord" EXACT [VHOG:0000787] synonym: "spinal cord floor" RELATED [VHOG:0000787] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0000787", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A multi-tissue structure that is part of a spinal cord and is part of a floor plate." [OBOL:automatic] [Term] id: UBERON:0003306 ! floor plate of neural tube name: floor plate of neural tube def: "A floor plate that is part of a neural tube [Automatically generated definition]." [OBOL:automatic] comment: Note that although 'floor plate' is classically defined as being located on the neural tube, in many AOs the floor plate continues post-embryonically after the neural tube has ceased to exist. We introduce this class for the neural tube specific structure subset: vertebrate_core synonym: "floorplate of neural tube" EXACT [OBOL:automatic] synonym: "neural tube floor plate" EXACT [OBOL:automatic] synonym: "neural tube floorplate" EXACT [OBOL:automatic] synonym: "floor plate neural tube" EXACT [ZFA:0001434] xref: EHDAA:2871 ! floor plate xref: EHDAA:910 ! floor plate xref: ZFA:0001434 ! floor plate neural tube xref: VHOG:0000300 ! floor plate neural tube xref: EHDAA2:0001256 ! neural tube floor plate xref: EMAPA:16165 ! floor plate of neural tube of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16531 ! floor plate of neural tube of future spinal cord of central nervous system of nervous system of organ system xref: EFO:0003688 ! floor plate neural tube intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0003079 ! floor plate intersection_of: part_of UBERON:0001049 ! neural tube xref: TAO:0001434 ! floor plate neural tube synonym: "floorplate neural tube" RELATED [VHOG:0000300] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0000300", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003080 name: anterior neural tube comment: editor note: TODO - add grouping class for the anterior end of the neural tube at all stages xref: VHOG:0001384 ! anterior neural tube xref: TAO:0007038 ! anterior neural tube xref: XAO:0000307 ! anterior neural tube xref: ZFA:0007038 ! anterior neural tube is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0003056 ! pre-chordal neural plate relationship: part_of UBERON:0001049 ! neural tube xref: AAO:0011012 ! anterior neural tube property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001384", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003081 alt_id: UBERON:0006258 name: lateral plate mesoderm def: "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]." [Wikipedia:Lateral_plate_mesoderm, MP:0010117] comment: AO notes: subclass of mesoderm in ZFA. subset: uberon_slim synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] xref: VHOG:0000118 ! lateral plate mesoderm xref: TAO:0000121 ! lateral plate mesoderm xref: XAO:0000311 ! lateral plate mesoderm xref: ZFA:0000121 ! lateral plate mesoderm xref: ncithesaurus:Lateral_Mesoderm ! Lateral Mesoderm xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray19_with_color.png/200px-Gray19_with_color.png is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: part_of UBERON:0000926 {source="EHDAA2", source="VHOG"} ! mesoderm relationship: develops_from UBERON:0000926 {source="EHDAA2", source="XAO"} ! mesoderm relationship: surrounds UBERON:0003887 ! intraembryonic coelom xref: AAO:0010574 ! lateral plate mesoderm xref: SCTID:361477005 ! Lateral plate mesoderm xref: EMAPA:16179 ! lateral plate mesenchyme xref: EHDAA2:0000919 ! lateral plate mesenchyme xref: EHDAA:379 ! lateral plate mesenchyme xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png property_value: external_definition "Portion of mesoderm traditionally thought to give rise to limb bones and parts of the girdles.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010574", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "The portion of the mesoderm of the trunk of vertebrate embryos lying lateral to the intermediate mesoderm. [...] [It] subdivides into two plates: one dorsal, called the somatopleure, and one ventral, called the splanchnopleure. [Gastrulation:_From_cells_to_embryo_(2004)_Cold_Spring_Harbor, Glossary_XV, New_York:_Cold_Spring_Harbor_Laboratory_Press, Stern_CD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000118", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "A ventrolateral zone of amphioxus mesoderm grows down to surround the gut. Homology of this zone to the lateral plate mesoderm of vertebrates is supported by site of origin and fate.[well established][VHOG]" xsd:string {external_class="VHOG:0000118", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1517749 [Term] id: UBERON:0009881 ! anterior lateral plate mesoderm name: anterior lateral plate mesoderm synonym: "ALPM" EXACT [ZFA:0005041] xref: TAO:0005041 ! anterior lateral plate mesoderm is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0003081 {source="ZFA"} ! lateral plate mesoderm xref: ZFA:0005041 ! anterior lateral plate mesoderm xref: EFO:0003704 ! anterior lateral plate mesoderm [Term] id: UBERON:0009910 name: posterior lateral plate mesoderm synonym: "PLPM" EXACT [ZFA:0005042] xref: TAO:0005042 ! posterior lateral plate mesoderm is_a: UBERON:0000926 {source="ZFA"} ! mesoderm relationship: part_of UBERON:0003081 {source="ZFA"} ! lateral plate mesoderm xref: ZFA:0005042 ! posterior lateral plate mesoderm xref: EFO:0003705 ! posterior lateral plate mesoderm [Term] id: UBERON:0004871 name: somatic layer of lateral plate mesoderm def: "Layer of lateral plate mesoderm that forms the future body wall - underlies the ectoderm[WP]." [Wikipedia:Lateral_plate_mesoderm#Division_into_layers] comment: check BILA synonym: "outer layer of lateral plate mesoderm" EXACT [] synonym: "somatic mesoderm" RELATED [BILA:0000047] synonym: "parietal mesoderm" RELATED [ISBN:9780878932504 "Developmental Biology"] xref: XAO:0000271 ! somatic layer of lateral plate mesoderm xref: BILA:0000047 ! somatic mesoderm is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003081 ! lateral plate mesoderm xref: AAO:0011100 ! somatic layer of lateral plate mesoderm [Term] id: UBERON:0004872 ! splanchnic layer of lateral plate mesoderm name: splanchnic layer of lateral plate mesoderm def: "Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]." [Wikipedia:Lateral_plate_mesoderm#Division_into_layers] comment: AO notes: We group the BILA class here. Considering adding more general class for metazoa grouping cardiogenic successors synonym: "inner layer of lateral plate mesoderm" EXACT [] synonym: "visceral mesoderm" BROAD [BILA:0000044, http://www.stedmans.com/, http://www.drugs.com/dict/visceral-mesoderm.html] synonym: "splanchnic mesoderm" RELATED [ISBN:9780878932504 "Developmental Biology"] xref: XAO:0000276 ! splanchnic layer of lateral plate mesoderm xref: BILA:0000044 ! visceral mesoderm is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003081 ! lateral plate mesoderm xref: AAO:0011102 ! splanchnic layer of lateral plate mesoderm [Term] id: UBERON:0004873 name: splanchnopleure def: "a structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]." [Wikipedia:Splanchnopleure] synonym: "ventral splanchnic mesoderm" RELATED [Wikipedia:Intraembryonic_coelom] comment: todo - check relationship to LPM xref: EHDAA:383 ! splanchnopleure xref: EMAPA:16181 ! splanchnopleure xref: VHOG:0000558 ! splanchnopleure xref: EHDAA2:0001903 ! splanchnopleure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/28/Gray16.png/200px-Gray16.png is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003081 {source="EHDAA2"} ! lateral plate mesenchyme relationship: overlaps UBERON:0000925 ! endoderm xref: ncithesaurus:Splanchnopleure ! Splanchnopleure xref: UMLS:C1519472 [Term] id: UBERON:0004874 ! somatopleure name: somatopleure def: "a structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]." [Wikipedia:Somatopleure] comment: todo - check relationship to LPM xref: EHDAA:381 ! somatopleure xref: EMAPA:16180 ! somatopleure xref: VHOG:0000557 ! somatopleure xref: EHDAA2:0001847 ! somatopleure xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/28/Gray16.png/200px-Gray16.png is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003081 {source="EHDAA2"} ! lateral plate mesenchyme relationship: overlaps UBERON:0000924 ! ectoderm xref: ncithesaurus:Somatopleure ! Somatopleure xref: UMLS:C1519423 [Term] id: UBERON:0010377 ! mesenchyme from somatopleure name: mesenchyme from somatopleure comment: Editor notes: the way this class is defined also includes extraembryonic mesenchyme such as the amniotic mesenchyme; in future this may be restricted to embryonic derivatives is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0004874 ! somatopleure relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire mesenchyme xref: EHDAA2:0001120 ! mesenchyme from somatopleure def: "Mesenchyme that develops_from a somatopleure." [OBOL:automatic] [Term] id: UBERON:0010378 ! mesenchyme from splanchnopleure name: mesenchyme from splanchnopleure is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0004873 ! splanchnopleure relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire mesenchyme xref: EHDAA2:0001122 ! mesenchyme from splanchnopleure def: "Mesenchyme that develops_from a splanchnopleure." [OBOL:automatic] [Term] id: UBERON:0008919 name: obsolete mesenchyme from somatopleure is_obsolete: true replaced_by: UBERON:0010377 ! mesenchyme from somatopleure [Term] id: UBERON:0008920 name: obsolete mesenchyme from splanchnopleure is_obsolete: true replaced_by: UBERON:0010378 ! mesenchyme from splanchnopleure [Term] id: UBERON:0005876 name: undifferentiated genital tubercle def: "A genital tubercle is a body of tissue present in the development of the urinary and reproductive organs. It forms in the ventral, caudal region of mammalian embryos of both sexes, and eventually develops into a phallus. In the human fetus the genital tubercle develops around week 4 of gestation, and by week 9 becomes recognizably either a clitoris or penis. This should not be confused with the sinus tubercle which is a proliferation of endoderm induced by paramesonephic ducts. Even after the phallus is developed, the term genital tubercle remains, but only as the terminal end of it[2], which develops into either the glans penis or the glans clitoridis. The genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month is a major determinant of phallus size at birth.[WP]." [Wikipedia:Genital_tubercle] comment: Taxon notes: todo - add taxon constraints. AO notes: we assume the EMAPA class is the undifferentiated form based on TS timings synonym: "undifferentiated genital tubercle" EXACT [VHOG:0000583] synonym: "tuberculum phallicum" RELATED LATIN [Wikipedia:Genital_tubercle] synonym: "phallic tubercle" RELATED [] synonym: "tuberculum genitale" RELATED LATIN [Wikipedia:Genital_tubercle] synonym: "genital tubercle" RELATED [EMAPA:17382] xref: EMAPA:17382 ! genital tubercle xref: EHDAA2:0000705 ! genital tubercle xref: EHDAA:5925 ! genital tubercle of reproductive system xref: VHOG:0000583 ! undifferentiated genital tubercle is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0009196 {source="EHDAA2"} ! indifferent external genitalia relationship: develops_from UBERON:0004874 ! somatopleure xref: SCTID:308798005 ! Entire genital tubercle xref: http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png property_value: external_definition "embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin; GT development is indistinguishable in male and female mouse embryos until ~E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP]" xsd:string {ontology="MP"} property_value: external_definition "The eminence in the embryo which develops into the clitoris or penis. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000583", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/genital+tubercle", source="http://bgee.unil.ch/"} property_value: homology_notes "In mammalian embryos, male and female external genitalia develop from the genital tubercle.[well established][VHOG]" xsd:string {external_class="VHOG:0000583", ontology="VHOG", source="DOI:10.1242/dev.036830 Seifert AW\, Yamaguchi T\, Cohn MJ\, Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development. Development (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0011757 ! differentiated genital tubercle name: differentiated genital tubercle def: "." [Wikipedia:Primordial_phallus] synonym: "phallus" RELATED [Wikipedia:Primordial_phallus] synonym: "primordial phallus" RELATED [Wikipedia:Primordial_phallus] synonym: "phallus primordialis" RELATED LATIN [Wikipedia:Primordial_phallus] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0004176 ! external genitalia relationship: develops_from UBERON:0005876 ! genital tubercle xref: ncithesaurus:Primordial_Phallus ! primordial phallus xref: UMLS:C1514448 [Term] id: UBERON:0006233 name: female genital tubercle subset: emapa_ehdaa2 synonym: "genital tubercle of female" EXACT [EMAPA:18680] xref: EMAPA:18680 ! genital tubercle of female xref: RETIRED_EHDAA2:0000500 ! female genital tubercle xref: VHOG:0000666 ! female genital tubercle xref: EHDAA:8118 ! genital tubercle of female intersection_of: UBERON:0011757 ! differentiated genital tubercle intersection_of: part_of UBERON:0000474 ! female reproductive system def: "A differentiated genital tubercle that is part of a female reproductive system." [OBOL:automatic] relationship: part_of UBERON:0005056 {is_inferred="true", source="reference_0000032"} ! external female genitalia [Term] id: UBERON:0006261 name: male genital tubercle subset: emapa_ehdaa2 synonym: "genital tubercle of male" EXACT [EMAPA:17969] xref: EMAPA:17969 ! genital tubercle of male xref: RETIRED_EHDAA2:0001048 ! male genital tubercle xref: VHOG:0000667 ! male genital tubercle xref: EHDAA:8138 ! genital tubercle of male intersection_of: UBERON:0011757 ! differentiated genital tubercle intersection_of: part_of UBERON:0000079 ! male reproductive system def: "A differentiated genital tubercle that is part of a male reproductive system." [OBOL:automatic] relationship: part_of UBERON:0004053 {is_inferred="true", source="reference_0000032"} ! external male genitalia [Term] id: UBERON:0011754 name: genital swelling def: "Paired structures in the human embryo that represent the final stage of development of the caudal end of the external genitals before sexual differentiation. In both males and females the two swellings merge: in the female, they become the posterior labial commissure; In the male, they become the scrotum" [Wikipedia:Labioscrotal_swelling] comment: Editor notes: todo - add parthood relationships to tubercles synonym: "labioscrotal swelling" EXACT [] synonym: "tuberculum labioscrotale" RELATED LATIN [Wikipedia:Labioscrotal_swelling] is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0000990 ! reproductive system relationship: develops_from UBERON:0005876 ! undifferentiated genital tubercle xref: VHOG:0000976 ! labial swelling [Term] id: UBERON:0011755 name: female labial swelling intersection_of: UBERON:0011754 ! genital swelling intersection_of: part_of UBERON:0000474 ! female reproductive system relationship: develops_from UBERON:0006233 ! female genital tubercle synonym: "labial swelling" BROAD [EMAPA:18329] xref: EHDAA2:0000501 ! female labial swelling xref: EHDAA:9363 ! labial swelling xref: EMAPA:18329 ! labial swelling xref: EMAPA:30423 ! labioscrotal swelling of female synonym: "labioscrotal swelling of female" EXACT [EMAPA:30423] def: "A genital swelling that is part of a female reproductive system." [OBOL:automatic] [Term] id: UBERON:0011756 name: male genital swelling intersection_of: UBERON:0011754 ! genital swelling intersection_of: part_of UBERON:0003135 ! male reproductive organ relationship: develops_from UBERON:0006261 ! male genital tubercle synonym: "labioscrotal swelling of male" EXACT [EMAPA:30509] xref: EHDAA2:0001049 ! male genital swelling def: "A genital swelling that is part of a male reproductive organ." [OBOL:automatic] [Term] id: UBERON:0005792 name: nephric ridge def: "Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions. " [http://cwx.prenhall.com/bookbind/pubbooks/martini10/chapter27/custom2/deluxe-content.html] comment: TODO - check ridge vs cord vs nephrogenic cord vs blastema synonym: "nephric cord" RELATED [VHOG:0001240] xref: EMAPA:16368 ! nephric cord xref: VHOG:0001240 ! nephric cord xref: EHDAA2:0001242 ! nephric cord xref: EHDAA:1015 ! nephric cord is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004122 ! genitourinary system relationship: part_of UBERON:0001008 ! urinary system [Term] id: UBERON:0004875 ! nephrogenic cord name: nephrogenic cord def: "a portion of the urogenital ridge which is the source of much of the urinary system[WP]." [Wikipedia:Nephrogenic_cord] comment: part_of or develops_from urogenital ridge? xref: FMA:72168 ! nephrogenic cord is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0004876 ! urogenital ridge xref: ncithesaurus:Nephrogenic_Cord ! Nephrogenic Cord xref: SCTID:361405003 ! Nephrogenic cord synonym: "chorda nephrogenica" RELATED LATIN [Wikipedia:Nephrogenic_cord] xref: UMLS:C1283944 [Term] id: UBERON:0005753 ! caudal part of nephrogenic cord name: caudal part of nephrogenic cord def: "the metanephros develops from the most caudal part of the nephrogenic cord that is itself derived from the intermediate plate mesoderm." [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "rear portion of nephrogenic cord" EXACT [Wikipedia:Metanephros#Metanephros] synonym: "rear part of nephrogenic cord" EXACT [OBOL:automatic] synonym: "caudal portion of nephrogenic cord" EXACT [OBOL:automatic] synonym: "caudal region of nephrogenic cord" EXACT [OBOL:automatic] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004875 ! nephrogenic cord [Term] id: UBERON:0005754 ! rostral part of nephrogenic cord name: rostral part of nephrogenic cord def: "The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros." [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004875 ! nephrogenic cord [Term] id: UBERON:0004876 name: urogenital ridge def: "One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]." [Wikipedia:Urogenital_folds, MP:anna, MP:0011835] comment: Less commonly, urogenital fold refers to the fold in the mesonephros which is the precursor of e.g. the suspensory ligament of the ovary. This is the case in older versions of Gray's anatomy[WP] synonym: "urogenital fold" EXACT [EHDAA2:0004022] synonym: "urethral fold" EXACT [] xref: BTO:0001402 ! urogenital ridge xref: EMAPA:30888 ! urethral fold of urinary system xref: EMAPA:30899 ! urethral fold of urethra of urogenital sinus of urinary system is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0009196 {source="EHDAA2"} ! indifferent external genitalia relationship: develops_into UBERON:0004176 ! external genitalia relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm relationship: develops_from UBERON:0012292 {source="EHDAA2"} ! embryonic cloacal fold xref: ncithesaurus:Urogenital_Ridge ! Urogenital Ridge xref: EHDAA2:0004022 ! urogenital fold xref: SCTID:308801004 ! Entire urogenital ridge xref: UMLS:C0231047 [Term] id: UBERON:0005294 ! genital ridge name: genital ridge def: "The precursor to the gonads." [Wikipedia:Gonadal_ridge] comment: TODO - check developmental relationships. merge with urogenital ridge? synonym: "gonadal ridge" EXACT [Wikipedia:Gonadal_ridge] xref: XAO:0000018 ! genital ridge xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/30/Gray1106.png/200px-Gray1106.png is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0004876 ! urogenital ridge relationship: part_of UBERON:0004122 ! genitourinary system xref: ncithesaurus:Gonadal_Ridge ! Gonadal Ridge xref: AAO:0011047 ! genital ridge xref: EHDAA2:0004044 ! gonadal ridge xref: SCTID:361399001 ! Entire genital ridge synonym: "crista gonadalis" RELATED LATIN [Wikipedia:Gonadal_ridge] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1106.png xref: EFO:0001414 ! embryonic gonadal ridge xref: UMLS:C1512243 [Term] id: UBERON:0012292 name: embryonic cloacal fold def: "One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly" [MP:anna, MP:0011836] comment: We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts synonym: "cloacal fold" BROAD [EHDAA2:0004009] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0012469 {source="EHDAA2"} ! external anal region relationship: adjacent_to UBERON:0006217 ! cloacal membrane xref: EHDAA2:0004009 ! cloacal fold [Term] id: UBERON:0012293 name: anal fold def: "a slight elevation flanking the cloacal membrane and derived from a cloacal fold; anal folds form the border of the anus." [http://medical-dictionary.thefreedictionary.com/anal+fold] is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0001353 ! anal region relationship: develops_from UBERON:0012292 {source="EHDAA2"} ! embryonic cloacal fold xref: EHDAA2:0004012 ! anal fold [Term] id: UBERON:0013244 name: vaginal plate def: "The vaginal plate is a precursor to the inferior portion of the vagina. They form from sinovaginal bulbs." [Wikipedia:Vaginal_plate] is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0013245 ! sinovaginal bulb relationship: part_of UBERON:0000164 ! primitive urogenital sinus xref: ncithesaurus:Vaginal_Plate ! vaginal plate xref: UMLS:C1519928 [Term] id: UBERON:0013245 ! sinovaginal bulb name: sinovaginal bulb def: "solid evaginations of the UG sinus that develops into a vaginal plate that which will will eventually canalize to form the inferior portion of the vagina." [UBERON:cjm] xref: ncithesaurus:Sinovaginal_Bulb ! sinovaginal bulb is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000164 ! primitive urogenital sinus xref: UMLS:C1519330 [Term] id: UBERON:0003086 name: caudal artery def: "Extension of the dorsal aorta in the tail. Kimmel et al, 1995." [Wikipedia:Caudal_artery, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "CA" RELATED [] xref: VHOG:0000123 ! caudal artery xref: TAO:0000011 ! caudal artery xref: XAO:0000364 ! caudal artery xref: ZFA:0000011 ! caudal artery xref: EFO:0003472 ! caudal artery is_a: UBERON:0001637 ! artery xref: AAO:0011023 ! caudal artery property_value: external_definition "The posterior extension of the dorsal aorta to the tail region, which degenerates at metamorphosis.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011023", date_retrieved="2012-06-20", source="ISBN:0-226-55763-4"} property_value: external_definition "Extension of the dorsal aorta in the tail. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000011", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of axial vasculature (TAO:0001073)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000011", date_retrieved="2012-08-14"} [Term] id: UBERON:0003088 name: caudal vein def: "Vein in the tail returning blood from the trunk and tail to the heart, leads directly into the posterial cardinal vein in the posterior trunk. Kimmel et al, 1995.[ZFIN]" [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "CV" RELATED [] xref: VHOG:0000126 ! caudal vein xref: TAO:0000180 ! caudal vein xref: XAO:0000390 ! caudal vein xref: ZFA:0000180 ! caudal vein xref: EFO:0003616 ! posterior caudal vein is_a: UBERON:0001638 ! vein xref: AAO:0011025 ! caudal vein xref: ncithesaurus:Caudal_Vein ! caudal vein property_value: external_definition "Vein in the tail returning blood from the trunk and tail to the heart, leads directly into the posterial cardinal vein in the posterior trunk. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000180", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from caudal vein plexus (TAO:0001286)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000180", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of axial vasculature (TAO:0001073)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000180", date_retrieved="2012-08-14"} property_value: external_definition "Vein in the tail returning blood from the trunk and tail to the heart, leads directly into the posterior cardinal vein in the posterior trunk[XB:curator]." xsd:string {source="XB:curator"} [Term] id: UBERON:0003481 name: tail vein def: "A vein that is part of a tail [Automatically generated definition]." [OBOL:automatic, Wikipedia:Tail_vein] comment: Editors note: see also caudal vein synonym: "post-vent region vein" EXACT [OBOL:automatic] synonym: "vein of post-vent region" EXACT [OBOL:automatic] synonym: "vein of tail" EXACT [OBOL:automatic] synonym: "caudal vein" RELATED [Wikipedia:Tail_vein] xref: MA:0002233 ! tail vein xref: XAO:0000393 ! tail vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0007812 ! post-anal tail xref: AAO:0011105 ! tail vein [Term] id: UBERON:0010204 name: tail vasculature comment: AO notes: isa blood vessel in XAO synonym: "tail vasculature" RELATED [ZFA:0005037] synonym: "post-vent vasculature" EXACT [ZFA:0005037] intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0007812 ! post-anal tail xref: ZFA:0005037 ! post-vent vasculature xref: XAO:0004151 ! tail vasculature xref: TAO:0005037 ! tail vasculature def: "A vasculature that is part of a post-anal tail." [OBOL:automatic] [Term] id: UBERON:0003090 name: supraorbital lateral line def: "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)" [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "supraorbital line" EXACT [ZFA:0000443] xref: VHOG:0000128 ! supraorbital lateral line xref: TAO:0000443 ! supraorbital lateral line xref: XAO:0000442 ! supraorbital lateral line xref: ZFA:0000443 ! supraorbital lateral line is_a: UBERON:0010202 ! lateral line xref: AAO:0011103 ! supraorbital lateral line property_value: external_definition "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000443", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of anterior lateral line (TAO:0001470)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000443", date_retrieved="2012-08-14"} property_value: external_definition "The lateral line that is located above the eye. [Butler_AB_and_Hodos_W, Comparative_vertebrate_neuroanatomy:_Evolution_and_Adaptation_(1996)_New_York:_Wiley-Liss_Inc., p.27][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000128", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The mechanosensory lateral line system is widely distributed in aquatic anamniotes. It was apparently present in the earliest vertebrates, as it has been identified in agnathans, cartilaginous fishes, bony fishes, lungfishes, the crossopterygian Latimeria, and aquatic amphibians.[well established][VHOG]" xsd:string {external_class="VHOG:0000128", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.195", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009722 ! entire pharyngeal arch endoderm name: entire pharyngeal arch endoderm synonym: "pharyngeal arch endoderm" RELATED [EHDAA2:0004621] is_a: UBERON:0000477 {source="EHDAA2"} ! anatomical cluster relationship: part_of UBERON:0003929 {source="EHDAA2"} ! gut epithelium xref: EHDAA2:0004621 ! pharyngeal arch endoderm [Term] id: UBERON:0007690 ! early pharyngeal endoderm name: early pharyngeal endoderm def: "." [http://dev.biologists.org/content/128/22/4573.full] comment: relation conflict: ZFA vs EHDAA2. Note EHDAA2 term renamed to 'early PA endoderm' synonym: "pharyngeal region endoderm" RELATED [EHDAA2:0001456] synonym: "pharyngeal arch endoderm" RELATED [] synonym: "pharyngeal endoderm" RELATED [ZFA:0001104] synonym: "early pharyngeal arch endoderm" EXACT [EHDAA2:0001457] xref: ZFA:0001104 ! pharyngeal endoderm xref: EHDAA:962 ! endoderm xref: EFO:0003626 ! pharyngeal endoderm xref: EHDAA2:0001457 ! early pharyngeal arch endoderm is_a: UBERON:0000925 {source="ZFA"} ! endoderm relationship: develops_from UBERON:0000925 {source="EHDAA2"} ! endoderm relationship: part_of UBERON:0008814 ! pharyngeal system relationship: part_of UBERON:0009722 {source="cjm"} ! entire pharyngeal arch endoderm xref: TAO:0001104 ! pharyngeal endoderm [Term] id: UBERON:0003351 name: pharyngeal epithelium def: "An epithelium that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "epithelial tissue of pharynx" EXACT [OBOL:automatic] synonym: "pharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "pharynx epithelium" EXACT [OBOL:automatic] synonym: "epithelium of pharynx" EXACT [OBOL:automatic] xref: EMAPA:16708 ! epithelium of pharynx of foregut xref: EMAPA:16551 ! epithelium of pharyngeal region xref: ZFA:0001174 ! pharyngeal epithelium xref: MA:0002725 ! pharynx epithelium xref: RETIRED_EHDAA2:0001460 ! pharynx epithelium xref: XAO:0003202 ! pharyngeal epithelium is_a: UBERON:0000490 {source="ZFA", gci_relation="part_of", gci_filler="NCBITaxon:7955"} ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 {source="ZFA"} ! chordate pharynx relationship: develops_from UBERON:0007690 {source="ZFA"} ! early pharyngeal endoderm xref: TAO:0001174 ! pharyngeal epithelium property_value: external_definition "Epithelium lining the pharynx consisting largely of simple columnar epithelium with a short segment (1mm) of stratified squamous epithelium on the ventral side. Chen et al, 2007.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001174", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0003091 ! thyroid primordium name: thyroid primordium def: "The initial thyroid precursor, the thyroid primordium, starts as a simple midline thickening and develops to form the thyroid diverticulum. This structure is initially hollow, although it later solidifies and becomes bilobed. The 2 lobes are located on either side of the midline and are connected via an isthmus." [http://emedicine.medscape.com/article/845125-overview] subset: vertebrate_core comment: In all vertebrates the thyroid arises from the ventral aspect of the second pouch[PMID:16313389]. Note that we follow EHDAA2 in dividing this into endoderm and mesenchyme. In this ontology we place the broad developmental relationship at this level, and include specific relationships to the pharyngeal endoderm at the level of the endoderm xref: TAO:0001081 ! thyroid primordium xref: XAO:0000444 ! thyroid primordium xref: ZFA:0001081 ! thyroid primordium xref: ncithesaurus:Thyroid_Primordium ! Thyroid Primordium xref: EHDAA:952 ! thyroid primordium xref: EHDAA2:0002033 ! thyroid primordium xref: BTO:0004709 ! thyroid primordium xref: EMAPA:16361 ! thyroid primordium of gland of foregut diverticulum xref: EMAPA:16558 ! thyroid primordium of gland of foregut is_a: UBERON:0000479 {source="ZFA"} ! tissue is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0000949 {source="ZFA"} ! endocrine system relationship: develops_from UBERON:0007123 {source="PMID:16313389", source="ISBN10:0073040584"} ! pharyngeal pouch 2 xref: AAO:0011106 ! thyroid primordium xref: UMLS:C1519512 property_value: external_definition "Portion of tissue part of the pharyngeal endoderm that is fated to become thyroid follicle[ZFIN:curator]." xsd:string {source="ZFIN:curator"} [Term] id: UBERON:0007689 ! thyroid diverticulum name: thyroid diverticulum def: "endodermal bud derived from the endodermal epithelium of the embryonic pharyngeal floor[MP]. The thyroid diverticulum is the embryological structure from which thyroid follicular cells derive. It grows from the floor of the pharnyx[WP]." [Wikipedia:Thyroid_diverticulum, MP:0004662] is_a: UBERON:0001048 ! primordium relationship: develops_from UBERON:0003091 ! thyroid primordium synonym: "saccus thyroideus; diverticulum thyroideum" RELATED LATIN [Wikipedia:Thyroid_diverticulum] [Term] id: UBERON:0003261 alt_id: UBERON:0005235 name: thyroid primordium endoderm synonym: "endoderm of thyroid primordium" EXACT [OBOL:automatic] xref: EHDAA:956 ! endoderm xref: RETIRED_EHDAA2:0002035 ! thyroid primordium endoderm xref: EMAPA:25357 ! endoderm of thyroid primordium of gland of foregut diverticulum xref: EMAPA:16560 ! endoderm of thyroid primordium of gland of foregut xref: VHOG:0001089 intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0003091 ! thyroid primordium relationship: develops_from UBERON:0007690 {source="ZFA-propagated"} ! early pharyngeal endoderm def: "An endoderm that is part of a thyroid primordium." [OBOL:automatic] [Term] id: UBERON:0003092 name: ultimobranchial body def: "Pharyngeal pouch derivative, usually paired cell masses located in the neck region[Kardong]. The ultimobranchial body or gland is a small organ found in the neck region of many animals. In humans, the ultimobranchial body is an embryological structure that gives rise to the calcitonin-producing cells—also called parafollicular cells or clear cells—of the thyroid gland. In humans, this body is a derivative of the ventral recess of the fourth pharyngeal pouch (or fifth) [WP,unvetted]. The ultimobranchial bodies of lower vertebrates contain large amounts of calcitonin. In mammals the bodies fuse with the thyroid gland and are thought to develop into the parafollicular cells. (Stedman, 25th ed)" [Wikipedia:Ultimopharyngeal_body, MESH:A13.939, ISBN10:0073040584] comment: Developmental origins vary across species. PMID:16313389 says: the most posterior pouch generates the ultimobranchial bodies in most vertebrate classes, but mammals do not contain this structure // The neural crest is the source of ultimobranchial cells[Kardong]. WP says pouch 4, but this isn't supported by Kardong (table 13.1 or fig 15.5). EHDAA2 says 6th arch mesenchyme subset: uberon_slim subset: vertebrate_core synonym: "postbranchial body" RELATED [Wikipedia:Ultimobranchial_body] synonym: "ultimobranchial" RELATED [Wikipedia:Ultimobranchial_body] synonym: "ultimobranchial bodies" RELATED PLURAL [Wikipedia:Ultimobranchial_body] synonym: "ultimobranchial gland" EXACT [Wikipedia:Ultimobranchial_body] synonym: "ultimopharyngeal gland" EXACT [Wikipedia:Ultimobranchial_body] synonym: "ultimopharyngeal body" EXACT [Wikipedia:Ultimobranchial_body] synonym: "corpus ultimopharyngeum" EXACT [Wikipedia:Ultimobranchial_body] xref: EHDAA:2987 ! ultimobranchial body xref: EHDAA:9139 ! ultimobranchial body xref: GAID:1246 ! ultimobranchial body xref: VHOG:0001185 ! ultimobranchial body xref: TAO:0001448 ! ultimobranchial body xref: XAO:0000452 ! ultimobranchial body xref: ZFA:0001448 ! ultimobranchial body xref: EHDAA2:0002103 ! ultimobranchial body xref: MESH:A13.939 ! ultimobranchial body is_a: UBERON:0000061 ! anatomical structure relationship: develops_from UBERON:0004117 {source="ISBN10:0073040584"} ! pharyngeal pouch relationship: develops_from UBERON:0003117 {source="XAO"} ! pharyngeal arch 6 relationship: develops_from UBERON:0007126 {source="Wikipedia", source="ISBN10:0073040584"} ! pharyngeal pouch 5 relationship: part_of UBERON:0000949 ! endocrine system relationship: has_part CL:0000570 {source="Wikipedia"} ! parafollicular cell relationship: has_part PR:000027222 {source="Wikipedia"} ! calcitonin xref: AAO:0010547 ! ultimobranchial body property_value: external_definition "Anatomical structure which includes small, calcitonin producing glands originating as epithelial growths from the sixth pharyngeal pouch.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010547", date_retrieved="2012-06-20", source="AAO:BJB"} xref: SCTID:345552007 ! Entire ultimobranchial gland property_value: external_definition "The glandular tissue originating from the fifth branchial pouch which combines with the buccal cavity outgrowth to form the thyroid and contributes calcitonin-secreting cells to the gland. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001185", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/ultimobranchial+body", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) ultimobranchial bodies that develop in all vertebrates from the ventral or posterior surface of the last pair of pharyngeal pouches. The ultimobranchial bodies are vestigial in most mammals (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001185", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.523", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003093 name: occipital lateral line def: "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)" [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "supratemporal lateral line" RELATED [] xref: VHOG:0000131 ! occipital lateral line xref: TAO:0000400 ! occipital lateral line xref: XAO:0000458 ! occipital lateral line xref: ZFA:0000400 ! occipital lateral line is_a: UBERON:0010202 ! lateral line xref: AAO:0011075 ! occipital lateral line property_value: external_definition "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000400", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of anterior lateral line (TAO:0001470)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000400", date_retrieved="2012-08-14"} property_value: homology_notes "The mechanosensory lateral line system is widely distributed in aquatic anamniotes. It was apparently present in the earliest vertebrates, as it has been identified in agnathans, cartilaginous fishes, bony fishes, lungfishes, the crossopterygian Latimeria, and aquatic amphibians.[well established][VHOG]" xsd:string {external_class="VHOG:0000131", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.195", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003094 name: infraorbital lateral line def: "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)" [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "infraorbital line" EXACT [ZFA:0000524] xref: VHOG:0000132 ! infraorbital lateral line xref: TAO:0000524 ! infraorbital lateral line xref: XAO:0000459 ! infraorbital lateral line xref: ZFA:0000524 ! infraorbital lateral line is_a: UBERON:0010202 ! lateral line relationship: part_of UBERON:0002540 ! lateral line system xref: AAO:0011053 ! infraorbital lateral line property_value: external_definition "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000524", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of anterior lateral line (TAO:0001470)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000524", date_retrieved="2012-08-14"} property_value: external_definition "The lateral line that is located below the eye. [Butler_AB_and_Hodos_W, Comparative_vertebrate_neuroanatomy:_Evolution_and_Adaptation_(1996)_New_York:_Wiley-Liss_Inc., p.27][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000132", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The mechanosensory lateral line system is widely distributed in aquatic anamniotes. It was apparently present in the earliest vertebrates, as it has been identified in agnathans, cartilaginous fishes, bony fishes, lungfishes, the crossopterygian Latimeria, and aquatic amphibians.[well established][VHOG]" xsd:string {external_class="VHOG:0000132", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.195", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003095 name: dorsal lateral line def: "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)" [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: TAO:0005112 ! dorsal lateral line xref: XAO:0000462 ! dorsal lateral line xref: ZFA:0005112 ! dorsal lateral line is_a: UBERON:0010202 ! lateral line xref: AAO:0011030 ! dorsal lateral line xref: VHOG:0001677 ! dorsal lateral line property_value: external_definition "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005112", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of posterior lateral line system (TAO:0001471)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005112", date_retrieved="2012-08-14"} property_value: homology_notes "The mechanosensory lateral line system is widely distributed in aquatic anamniotes. It was apparently present in the earliest vertebrates, as it has been identified in agnathans, cartilaginous fishes, bony fishes, lungfishes, the crossopterygian Latimeria, and aquatic amphibians.[well established][VHOG]" xsd:string {external_class="VHOG:0001677", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.195", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003096 name: middle lateral line def: "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)" [ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: VHOG:0000133 ! middle lateral line xref: TAO:0000344 ! middle lateral line xref: XAO:0000463 ! middle lateral line xref: ZFA:0000344 ! middle lateral line is_a: UBERON:0010202 ! lateral line property_value: external_definition "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000344", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from middle lateral line primordium (TAO:0005118)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000344", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of anterior lateral line (TAO:0001470)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000344", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of middle lateral line system (TAO:0005114)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000344", date_retrieved="2012-08-14"} property_value: homology_notes "The mechanosensory lateral line system is widely distributed in aquatic anamniotes. It was apparently present in the earliest vertebrates, as it has been identified in agnathans, cartilaginous fishes, bony fishes, lungfishes, the crossopterygian Latimeria, and aquatic amphibians.[well established][VHOG]" xsd:string {external_class="VHOG:0000133", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.195", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003097 name: dorsal fin def: "Median fin located on the dorsal surface of the organism." [VSAO:0000165, Wikipedia:Dorsal_fin] subset: uberon_slim xref: OpenCyc:Mx4rvVjbzZwpEbGdrcN5Y29ycA xref: TAO:0001173 ! dorsal fin xref: XAO:0000469 ! dorsal fin xref: ZFA:0001173 ! dorsal fin xref: OpenCyc:Mx4rvVjbzZwpEbGdrcN5Y29ycA ! dorsal fin xref: BTO:0004650 ! dorsal fin is_a: UBERON:0008897 ! fin relationship: in_median_plane_of UBERON:0001137 ! dorsum relationship: has_developmental_contribution_from UBERON:0003083 ! trunk neural crest xref: AAO:0010378 ! dorsal fin xref: VSAO:0000165 ! dorsal fin xref: SCTID:417127006 ! Dorsal fin structure synonym: "nageoire dorsale@fr" RELATED [VSAO:0000165] synonym: "notoptcérygie@fr" RELATED [VSAO:0000165] property_value: axiom_lost_from_external_ontology "is_a median fin[TAO]" xsd:string [Term] id: UBERON:0003083 name: trunk neural crest def: "Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]." [ISBN:0815318960, Wikipedia:Trunk_neural_crest] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "trunk crest" RELATED [] xref: VHOG:0000062 ! trunk neural crest xref: TAO:0001024 ! trunk neural crest xref: XAO:0000319 ! trunk neural crest xref: ZFA:0001024 ! trunk neural crest xref: EFO:0003605 ! trunk neural crest is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0002342 ! neural crest relationship: has_part CL:0000011 {source="ZFA"} ! trunk neural crest cell xref: AAO:0010582 ! trunk neural crest xref: EHDAA2:0001901 ! trunk neural crest property_value: external_definition "Post-cranial portion of the neural crest. Exact anatomical derivations not experimentally resolved in amphibians.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010582", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000062", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003099 name: cranial neural crest def: "The cranial neural crest arises in the anterior and populates the face and the pharyngeal arches giving rise to bones, cartilage, nerves and connective tissue [Wikipedia]." [Wikipedia:Cranial_neural_crest, ZFA:0001194, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "head crest" RELATED [] synonym: "head neural crest" RELATED [] synonym: "cephalic neural crest" RELATED [EMAPA:16091] xref: VHOG:0000063 ! cranial neural crest xref: TAO:0001194 ! cranial neural crest xref: XAO:0001001 ! cranial neural crest xref: ZFA:0001194 ! cranial neural crest xref: EMAPA:16091 ! neural crest xref: EFO:0003645 ! cranial neural crest is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0002342 ! neural crest relationship: has_part CL:0000008 ! cranial neural crest cell xref: AAO:0010580 ! cranial neural crest xref: EHDAA2:0004420 ! head neural crest synonym: "crista neuralis cranialis" RELATED LATIN [Wikipedia:Cranial_neural_crest] property_value: external_definition "Anterior most portion of the neural crest. Migrates in three highly conserved streams: mandibular, hyoid and branchial.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010580", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Neural crest that is part of the head.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001194", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000063", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0007681 name: facial neural crest def: "Cranial neural crest that is part of the facial region." [ZFA:0000875] xref: VHOG:0001209 ! facial neural crest xref: ZFA:0000875 ! facial neural crest xref: EMAPA:16311 ! facial neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest relationship: part_of UBERON:0003104 {source="OG"} ! mesenchyme relationship: part_of UBERON:0007213 {source="EMAPA"} ! mesenchyme derived from head neural crest xref: TAO:0000875 ! facial neural crest property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001209", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003100 name: female organism def: "Gonochoristic organism that can produce female gametes." [CARO:0000028] subset: vertebrate_core synonym: "female human body" NARROW SENSU [FMA:67812] synonym: "female" RELATED [TAO:0000303] xref: BILA:0000028 xref: CARO:0000028 ! female organism xref: FBbt:00007011 ! female organism xref: HAO:0000028 ! female organism xref: TAO:0000303 ! female xref: XAO:0003005 ! female organism xref: ZFA:0000303 ! female organism xref: FMA:67812 ! Female human body xref: TGMA:0001839 ! female organism is_a: UBERON:0000468 ! multi-cellular organism disjoint_from: UBERON:0003101 ! male organism relationship: spatially_disjoint_from UBERON:0003101 ! male organism xref: AAO:0010030 ! female organism xref: SCTID:362608006 ! Entire female [Term] id: UBERON:0003101 name: male organism def: "Gonochoristic organism that can produce male gametes." [CARO:0000027] subset: vertebrate_core synonym: "male human body" NARROW SENSU [FMA:67811] synonym: "male" RELATED [TAO:0000242] xref: BILA:0000027 xref: CARO:0000027 ! male organism xref: FBbt:00007004 ! male organism xref: HAO:0000027 ! male organism xref: TAO:0000242 ! male xref: XAO:0003006 ! male organism xref: ZFA:0000242 ! male organism xref: FMA:67811 ! Male human body xref: TGMA:0001838 ! male organism xref: WBbt:0007850 ! male is_a: UBERON:0000468 ! multi-cellular organism xref: AAO:0010033 ! male organism xref: SCTID:362609003 ! Entire male [Term] id: UBERON:0003103 name: compound organ def: "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." [CARO:0000024] subset: upper_level synonym: "organ" RELATED [] xref: BILA:0000024 xref: CARO:0000024 ! compound organ xref: HAO:0000024 ! compound organ xref: TAO:0000496 ! compound organ xref: XAO:0003041 ! compound organ xref: ZFA:0000496 ! compound organ xref: EHDAA2:0003024 ! compound organ xref: AEO:0000024 ! compound organ xref: TGMA:0001837 ! compound organ xref: TADS:0000598 ! compound organ is_a: UBERON:0000062 ! organ xref: AAO:0010015 ! compound organ subset: organ_slim xref: VHOG:0001723 ! compound organ [Term] id: UBERON:0009142 ! entire mesenchyme name: entire mesenchyme comment: consider adding new class (EMAPA:16097) for mesenchyme of embryo (some mesenchyme is extraembryonic - e.g. amnion mesoderm) alt_id: UBERON:0003313 is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: has_developmental_contribution_from UBERON:0000926 {source="EHDAA2"} ! mesoderm xref: EHDAA2:0001113 ! mesenchyme xref: EMAPA:16097 ! mesenchyme of embryo xref: EHDAA:177 ! mesenchyme [Term] id: UBERON:0003104 name: mesenchyme def: "Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage[XAO]. A mesh-like cell arrangement, less compact than an epithelium[ZFA]. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop[BTO]." [BTO:0001393, Wikipedia:Mesenchyme, ZFIN:curator] comment: Editors notes: the relationship to mesoderm is weaker than develops_from in order to have classes such as 'head mesenchyme from mesoderm' make sense subset: uberon_slim subset: vertebrate_core synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] synonym: "portion of mesenchyme tissue" EXACT [] xref: BTO:0001393 xref: VHOG:0000170 ! mesenchyme xref: TAO:0000393 ! mesenchyme xref: XAO:0003046 ! mesenchyme xref: ZFA:0000393 ! mesenchyme xref: ncithesaurus:Mesenchyme ! Mesenchyme xref: EHDAA2:0003145 ! mesenchymal tissue xref: AEO:0000145 ! mesenchymal tissue xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f4/Mesenchymal_Stem_Cell.jpg/200px-Mesenchymal_Stem_Cell.jpg xref: EV:0100007 ! mesenchyma is_a: UBERON:0000479 ! portion of tissue relationship: has_developmental_contribution_from UBERON:0000926 ! mesoderm relationship: part_of UBERON:0009142 ! whole mesenchyme xref: AAO:0010427 ! mesenchyme synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] xref: http://upload.wikimedia.org/wikipedia/commons/f/f4/Mesenchymal_Stem_Cell.jpg property_value: external_definition "Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010427", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "A mesh-like cell arrangement, less compact than an epithelium. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000393", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "mesenchymal" xsd:string xref: UMLS:C0162415 [Term] id: UBERON:0011585 name: cell condensation def: "Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995)." [VSAO:0000006] comment: Editor notes: consider obsoleting, coordinate with VSAO is_a: UBERON:0000061 {source="VSAO"} ! anatomical structure xref: VSAO:0000006 ! cell condensation xref: XAO:0004021 ! cell condensation [Term] id: UBERON:0005856 name: developing mesenchymal condensation def: "A delimited region of dense mesenchyme within looser mesenchyme." [AEO:0000148] synonym: "mesenchyme condensation" EXACT [EMAPA:25351] xref: EHDAA2_RETIRED:0003148 ! mesenchymal condensation xref: EMAPA:25351 ! mesenchyme condensation xref: EHDAA:8979 ! mesenchymal condensation xref: AEO:0000148 ! developing mesenchymal condensation is_a: UBERON:0007524 {source="AEO"} ! dense mesenchyme tissue is_a: UBERON:0011585 {source="cjm"} ! cell condensation relationship: composed_primarily_of CL:0000335 {source="AEO-modified-relation"} ! mesenchyme condensation cell [Term] id: UBERON:0005863 name: cartilaginous condensation def: "Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes." [GO:curator] comment: AO notes: isa cell condensation in VSAO; has_part chondroblast in AEO synonym: "cartilage condensation" EXACT [EMAPA:25353] synonym: "cartilagenous condensation" EXACT [EHDAA2:0003147] synonym: "chondrogenic condensation" EXACT [] synonym: "chondrogenic condensation" EXACT [VSAO:0000092] xref: EHDAA2:0003147 ! cartilagenous condensation xref: EMAPA:25353 ! cartilage condensation xref: AEO:0000147 ! cartilagenous condensation xref: VSAO:0000092 ! chondrogenic condensation is_a: UBERON:0005856 {source="AEO"} ! developing mesenchymal condensation relationship: develops_from UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0004288 {source="AEO"} ! skeleton xref: XAO:0004022 ! chondrogenic condensation [Term] id: UBERON:0005865 alt_id: UBERON:0008714 ! pre-muscle mass name: pre-muscle condensation synonym: "pre muscle mass" EXACT [] synonym: "premuscle mass" EXACT [] xref: EHDAA2_RETIRED:0003149 ! pre-muscle condensation xref: AEO:0000149 ! pre-muscle condensation intersection_of: UBERON:0005856 ! developing mesenchymal condensation intersection_of: composed_primarily_of CL:0000680 ! muscle precursor cell ! muscle precursor cell relationship: has_part CL:0000680 {source="AEO"} ! muscle precursor cell [Term] id: UBERON:0005866 ! pre-cartilage condensation name: pre-cartilage condensation def: "A closely packed aggregation of mesenchymal cells just prior to their differentiation into embryonic cartilage." [http://dictionary.reference.com/browse/precartilage] synonym: "precartilage condensation" EXACT [] synonym: "precartilagenous condensation" EXACT [] synonym: "pre-chondrogenic condensation" EXACT [] synonym: "prechondrogenic condensation" EXACT [] xref: EHDAA2:0003150 ! pre-cartilage condensation xref: AEO:0000150 ! pre-cartilage condensation is_a: UBERON:0005856 {source="AEO"} ! developing mesenchymal condensation relationship: part_of UBERON:0004288 {source="AEO"} ! skeleton [Term] id: UBERON:0003105 name: dorsal lateral plate region def: "Region located near the pronephros and pronephric ducts that is a site of hematopoiesis in the embryo. // Region where blood progenitor markers are expressed. Probable site of definitive hematopoiesis between 36hpf and 4dpf." [PMID:9618755, ZFIN:curator] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "AGM" RELATED [] synonym: "AGM region" RELATED [] synonym: "aorta gonad mesonephros region" RELATED [] synonym: "aorta-gonads-mesonephros region" RELATED [] synonym: "DLP" EXACT [] synonym: "ventral wall of dorsal aorta" EXACT [] synonym: "DA roof" RELATED [ZFA:0005028] synonym: "DA-PCV joint " EXACT [ZFA:0005028] synonym: "dorsal aorta - posterior cardinal vein joint" EXACT [ZFA:0005028] synonym: "DP joint" EXACT [ZFA:0005028] xref: TAO:0005028 ! ventral wall of dorsal aorta xref: XAO:0003051 ! dorsal lateral plate region xref: ZFA:0005028 ! ventral wall of dorsal aorta xref: EFO:0003699 ! ventral wall of dorsal aorta is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0000947 ! aorta relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0003081 ! lateral plate mesoderm xref: AAO:0011008 ! dorsal lateral plate region property_value: external_definition "Region located near the pronephros and pronephric ducts that is a site of hematopoiesis in the embryo.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011008", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Region where blood progenitor markers are expressed. Probable site of definitive hematopoiesis between 36hpf and 4dpf.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005028", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0012429 name: hemopoietic tissue def: "Blood-forming tissue, consisting of reticular fibers and cells. Also known as hemopoietic tissue" [http://encyclopedia2.thefreedictionary.com/hematopoietic+tissue] comment: Bone marrow in humans, kidney interstitium in Danio, within a stroma of reticuloendothelial tissue synonym: "haemopoietic tissue" EXACT [FMA:14073] synonym: "hematopoietic tissue" EXACT [FMA:14073] synonym: "textus haemopoieticus" EXACT [FMA:14073] intersection_of: UBERON:0000479 ! portion of tissue intersection_of: site_of GO:0030097 ! hemopoiesis relationship: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0002371 {source="FMA", gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! bone marrow xref: FMA:14073 ! hemopoietic tissue xref: ncithesaurus:Hematopoietic_Tissue ! hematopoietic tissue xref: UMLS:C0229619 xref: CALOHA:TS-2142 ! Hematopoietic tissue [Term] id: UBERON:0003111 name: sphenoid region def: "Anatomical cluster that forms the floor and sidewalls of the middle part of the cranium." [TAO:0000290, UBERONREF:0000007] xref: XAO:0003174 ! sphenoid region xref: ZFA:0000290 ! sphenoid region is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium xref: AAO:0010207 ! sphenoid region xref: TAO:0000290 ! sphenoid region property_value: external_definition "Anatomical cluster that forms the floor and sidewalls of the middle part of the neurocranium.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010207", date_retrieved="2012-06-20", source="AAO:EJS"} [Term] id: UBERON:0003112 name: olfactory region def: "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ." [TAO:0000351] synonym: "ethmoid region" RELATED [ZFA:0000351] xref: TAO:0000351 ! olfactory region xref: XAO:0003172 ! olfactory region xref: ZFA:0000351 ! olfactory region xref: EFO:0003525 ! olfactory region is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium xref: AAO:0010206 ! olfactory region xref: ncithesaurus:Olfactory_Region ! olfactory region property_value: external_definition "Anatomical cluster that is located in the anterior region of the neurocranium and provides structural support for the olfactory organs.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010206", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: external_definition "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the peripheral olfactory organ.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000351", date_retrieved="2012-08-14", source="TAO:MAH"} [Term] id: UBERON:0011595 ! jaw region name: jaw region comment: there are two jaw regions: the upper and lower. Each jaw region can be subdivided into left and right halves is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0000165 ! mouth property_value: seeAlso "http://eol.org/collections/11578" xsd:anyURI [Term] id: UBERON:0001708 name: jaw skeleton def: "Subdivision of skeleton which includes upper and lower jaw skeletons." [UBERON:cjm, Wikipedia:Jaw] comment: TODO: move ZFA:0001227 (it is the entire jaw skeleton). Editor notes: in FMA, the jaw is an organism subdivision cluster, and includes mucosal tissue such as the gingiva as parts. It appears to be skeletal in MA (and has teeth as parts). It is reasonable to assume that ZFA and XAO consider the upper and lower jaws to be skeletal elements or clusters. EHDAA2 also considers these clusters. TODO - follow EHDAA2 model. These arbitrary differences in terminology and classification have to be reconciled with the genuine well-known biological differences in the skeletal elements across vertebrates. Development notes: There are cellular contributions from all three embryonic germ layers: pharyngeal mesoderm, endoderm and neural crest that migrates out of the ectoderm (Noden, 1983). subset: uberon_slim subset: vertebrate_core synonym: "jaws" RELATED [] synonym: "jaw" EXACT [MA:0001905] synonym: "mandibular arch" RELATED [TAO:0001227] synonym: "oral jaw skeleton" RELATED [] synonym: "pharyngeal arch 1 skeleton" RELATED [] synonym: "visceral arch 1" RELATED [] synonym: "anterior splanchnocranium" RELATED [] synonym: "mandibular arch skeleton" EXACT [ZFA:0001227] synonym: "jaw cartilage" EXACT [ZFA:0001227] xref: FMA:54396 ! Jaw xref: GAID:214 ! jaw xref: galen:Jaw xref: MA:0001905 ! jaw xref: OpenCyc:Mx4rvVjjEZwpEbGdrcN5Y29ycA xref: ncithesaurus:Jaw ! Jaw xref: BTO:0001749 ! jaw xref: OpenCyc:Mx4rvVjjEZwpEbGdrcN5Y29ycA ! jaw xref: TAO:0001227 ! mandibular arch xref: ZFA:0001227 ! mandibular arch skeleton xref: MESH:A02.835.232.781.324.502 ! jaw xref: AAO:0000988 ! jaws is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0011595 ! jaw region relationship: overlaps UBERON:0008895 ! splanchnocranium relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: capable_of MBO:0000073 ! mastication relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest xref: SCTID:181811001 ! Entire jaw region property_value: external_definition "Skeletal and cartilage elements of the first pharyngeal arch.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001227", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0022359 [Term] id: UBERON:0001709 name: upper jaw region def: "Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [Wikipedia:Upper_jaw] comment: AO notes: Note isa/partof difference MA/FMA. See notes for jaw w.r.t skeletal element vs subdivision of head. See also subset: uberon_slim subset: vertebrate_core synonym: "dorsal mandibular arch" RELATED [] synonym: "palatoquadrate arch" RELATED INCONSISTENT [] synonym: "upper pharyngeal jaws" RELATED [] synonym: "dorsal pharyngeal arch 1" RELATED INCONSISTENT [] synonym: "maxillary part of mouth" EXACT [FMA:59399] xref: VHOG:0000454 ! upper jaw xref: AAO:0000620 ! upper_jaw xref: EHDAA:8025 ! upper jaw xref: ncithesaurus:Upper_Jaw ! Upper Jaw xref: EHDAA2:0004607 ! upper jaw region xref: EHDAA2:0002118 ! upper jaw xref: EMAPA:17924 ! upper jaw xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Gray189.png/200px-Gray189.png is_a: UBERON:0011595 ! jaw region relationship: part_of UBERON:0004089 ! midface relationship: spatially_disjoint_from UBERON:0001710 ! lower jaw region property_value: external_definition "Superior maxillary arch located on the anterior and lateral sides of the skull.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000620", date_retrieved="2012-06-20", source="AAO:LAP"} xref: SCTID:362636001 ! Upper jaw region property_value: homology_notes "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {external_class="VHOG:0000454", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003277 name: skeleton of upper jaw def: "A subdivision of skeleton that is part of the upper jaw region[Automatically generated definition]." [OBOL:automatic] synonym: "upper jaw skeleton" EXACT [] synonym: "upper jaw" BROAD [MA:0001908] xref: FMA:54397 ! Upper jaw xref: EHDAA:8041 ! skeleton xref: VHOG:0000429 ! upper jaw skeleton xref: EHDAA2:0002128 ! upper jaw skeleton xref: AAO:0000622 ! upper jaw skeleton xref: EMAPA:17927 ! skeleton of upper jaw xref: FMA:59399 ! maxillary part of mouth xref: MA:0001908 ! upper jaw xref: XAO:0003087 ! upper jaw intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: subdivision_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0001708 ! jaw skeleton property_value: homology_notes "The jaw joint of all jawed vertebrates, except for mammals, involves the quadrate and articular bones, or the posterior ends of the palatoquadrate and mandibular cartilages; A correlate of the conversion of the articular and quadrate bones to the malleus and incus is that all adult mammals have a jaw joint that lies between the dentary of the lower jaw and the squamosal bone of the skull roof.[well established][VHOG]" xsd:string {external_class="VHOG:0000429", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.241 and p.101", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004752 name: palatoquadrate cartilage def: "the dorsal component of the mandibular arch" [Wikipedia:Palatoquadrate] synonym: "dorsal mandibular cartilage" EXACT [ZFA:0001399] synonym: "pterygoquadrate" RELATED INCONSISTENT [ZFA:0001399] synonym: "quadrate cartilage" EXACT [ZFA:0001399] synonym: "palatoquadrate" EXACT [AAO:0000379] xref: AAO:0000379 ! palatoquadrate xref: ZFA:0001399 ! palatoquadrate cartilage is_a: UBERON:0011004 {source="ZFA"} ! pharyngeal arch cartilage relationship: part_of UBERON:0011085 {source="ZFA"} ! dorsal pharyngeal arch 1 relationship: part_of UBERON:0003108 {source="AAO"} ! suspensorium xref: TAO:0001399 ! palatoquadrate cartilage property_value: external_definition "Column of catilage, remnant in the adult of the larval palatoquadrate cartilage, that is located lateral or antero-lateral to the auditory capsule.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000379", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0011085 name: palatoquadrate arch def: "The dorsal portion of the first pharyngeal arch, comprising the upper jaw[ZFIN,VHOG]." [VHOG:0000511, http://purl.obolibrary.org/obo/uberon/tracker/153] synonym: "dorsal mandibular arch" RELATED [VHOG:0000511] synonym: "dorsal visceral arch 1" RELATED [VHOG:0000511] synonym: "dorsal pharyngeal arch 1" RELATED [VHOG:0000511] synonym: "palatoquadrate arch" RELATED [VHOG:0000511] synonym: "upper jaw" RELATED [VHOG:0000511] synonym: "upper pharyngeal jaw" RELATED [VHOG:0000511] synonym: "dorsal visceral arch 1" EXACT [ZFA:0001272] synonym: "upper pharyngeal jaw" EXACT [ZFA:0001272] is_a: UBERON:0010912 {source="cjm"} ! subdivision of skeleton relationship: part_of UBERON:0003277 ! skeleton of upper jaw relationship: develops_from UBERON:0004362 {modified_from="VHOG", notes="consider making more specific"} ! pharyngeal arch 1 relationship: part_of UBERON:0008895 {source="VHOG"} ! splanchocranium xref: TAO:0001272 ! palatoquadrate arch xref: ZFA:0001272 ! palatoquadrate arch xref: EFO:0003659 ! palatoquadrate arch xref: VHOG:0000511 ! dorsal pharyngeal arch 1 (also: UBERON:0007238 '1st arch maxillary component') property_value: homology_notes "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {external_class="VHOG:0000511", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003107 name: Meckel's cartilage def: "Meckel's cartilage is the bilaterally paired, rod-like, cartilaginous ventral component of the lower jar, or ventral mandibular arch. It is typically resorbed in adults." [PMID:3693112, Wikipedia:Meckel's_cartilage] comment: Taxon notes: functional lower jaw of Elasmobranchii and Holocephali, the embryonic lower jaw of other gnathostomous vertebrates[http://www.briancoad.com] subset: uberon_slim subset: vertebrate_core synonym: "cartilago arcus pharyngei primi" EXACT LATIN [] synonym: "Meckels cartilage" EXACT [] synonym: "primary mandinle" EXACT [http://www.briancoad.com] synonym: "ventral mandibular cartilage" EXACT [ZFA:0001205] xref: AAO:0000289 ! Meckel's_cartilage xref: EHDAA:7997 ! Meckel's cartilage xref: VHOG:0000249 ! Meckel's cartilage xref: MA:0001580 ! meckel's cartilage xref: TAO:0001205 ! Meckel's cartilage xref: XAO:0003085 ! Meckel's cartilage xref: ZFA:0001205 ! Meckel's cartilage xref: EHDAA2:0001072 ! Meckel's cartilage xref: EMAPA:17635 ! Meckel's cartilage of mandibular process xref: EMAPA:17907 ! Meckel's cartilage of lower jaw is_a: UBERON:0011004 {source="ZFA"} ! pharyngeal arch cartilage relationship: part_of UBERON:0003278 {source="EHDAA2"} ! skeleton of lower jaw relationship: part_of UBERON:0008895 {source="VHOG"} ! splanchnocranium relationship: develops_from UBERON:0006263 ! Meckel's cartilage pre-cartilage condensation xref: SCTID:308773009 ! Entire Meckel's cartilage property_value: external_definition "Paired, rod-shaped elements that extend the length of the mandible and lie between the dentaries and the angulosplenials. Can be reduced to various extent in adults.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000289", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Pharyngeal arch cartilage that is the cartilaginous embryonic component of the lower jaw, or ventral mandibular arch. It develops into the endochondral articular and retroarticular bones. Meckel's cartilage is paired.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001205", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "In all jawed vertebrates, including fish, the first pharyngeal arch generates the jaw apparatus. The neural crest cells of this arch migrate to form Meckel's cartilage, the precursor of the jaw.[well established][VHOG]" xsd:string {external_class="VHOG:0000249", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.16-17", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0011770 name: mentomeckelian def: "Paired, cylindrical, and small bones of endochondral origin that lie anteromedial to the anterior end of Meckel's cartilage. The precursors of the mentomeckelian bones are the larval infrarostral cartilages." [AAO:0000301] synonym: "Pars mentalis" RELATED [AAO:0000301] synonym: "dentale" RELATED [AAO:0000301] is_a: UBERON:0002513 {source="AAO"} ! endochondral bone relationship: part_of UBERON:0003278 {source="AAO"} ! skeleton of lower jaw xref: AAO:0000301 ! mentomeckelian [Term] id: UBERON:0003108 name: suspensorium def: "(1) the arrangement of bones which supports the jaw from the braincase; (2) in teleost fish, a large, usually triangular, bone which supports the jaw. The teleost suspensorium is formed by fusion of various elements which vary among different taxa." [http://palaeos.com/vertebrates/glossary/glossarySq.html] comment: Editor notes: requires review, possible split; TAO/ZFA structure is splanchoncranium (but includes some dermal bones as parts). Note AAO also includes 'palatoquadrate and suspensorium' as a class synonym: "hyopalatine" EXACT [TAO:0000444] synonym: "suspensoria" EXACT [TAO:0000444] synonym: "mandibular suspensorium" RELATED [] xref: AAO:0000596 ! suspensorium xref: TAO:0000444 ! suspensorium xref: XAO:0003086 ! suspensorium xref: ZFA:0000444 ! suspensorium is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0008895 {source="ZFA"} ! splanchnocranium [Term] id: UBERON:0002397 name: maxilla def: "The bone which normally forms the lateral upper jaw in osteichthyans, including tetrapods." [Wikipedia:Maxilla, http://palaeos.com/vertebrates/glossary/glossaryM.html] comment: Fusion of maxilla + premaxilla subset: uberon_slim subset: vertebrate_core synonym: "maxillae" RELATED PLURAL [] synonym: "upper jaw bone" BROAD [] synonym: "maxillary bone" RELATED [Wikipedia:Maxilla] xref: AAO:0000285 ! maxilla xref: EHDAA:8043 ! maxilla xref: FMA:9711 ! Maxilla xref: GAID:220 ! maxilla xref: VHOG:0001021 ! maxilla xref: MA:0001491 ! maxilla xref: TAO:0000270 ! maxilla xref: ZFA:0000270 ! maxilla xref: ncithesaurus:Maxilla ! Maxilla xref: galen:Maxilla ! maxilla xref: EHDAA2:0001068 ! maxilla xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Gray189.png/200px-Gray189.png xref: EMAPA:17639 ! maxilla of skeleton of maxillary process xref: EMAPA:17928 ! maxilla of skeleton of upper jaw xref: MESH:A02.835.232.781.324.502.645 ! maxilla is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0008907 {source="VSAO"} ! dermal bone is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone relationship: adjacent_to UBERON:0002244 ! premaxilla relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest relationship: part_of UBERON:0003277 {source="VHOG"} ! skeleton of upper jaw relationship: part_of UBERON:0003113 {source="Kardong", notes="facial series"} ! dermatocranium relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton xref: SCTID:181813003 ! Entire maxilla xref: VSAO:0000207 ! maxilla xref: http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray189.png property_value: external_definition "Paired, intramembranous bone located on the lateral sides of the skull, posterior to the premaxillae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000285", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "Dermal bone that forms part of the upper jaw, located antero-ventral to the premaxilla. The maxilla is a paired bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000270", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps autopalatine-maxillary joint (TAO:0001942)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000270", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps premaxillary-maxillary joint (TAO:0002260)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000270", date_retrieved="2012-08-14"} property_value: external_comment "In some teleosts, the maxilla is located postero-ventral to the supramaxilla. Commonly, the articular process of the maxilla articulates with the autopalatine and ethmoidal region antero-medially. The maxilla is usually the largest bone in the upper jaw assemblage.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000270", date_retrieved="2012-09-06", source="Curator"} property_value: has_relational_adjective "maxillary" xsd:string xref: UMLS:C0024947 [Term] id: UBERON:0001710 name: lower jaw region def: "Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [Wikipedia:Lower_jaw] comment: AO notes: Note isa/partof difference MA/FMA. See notes for jaw w.r.t skeletal element vs subdivision of head subset: uberon_slim subset: vertebrate_core synonym: "mandibular series" RELATED [] synonym: "mandibular part of mouth" EXACT [FMA:59398] xref: FMA:59398 ! mandibular part of mouth xref: EHDAA:7995 ! lower jaw xref: VHOG:0000453 ! lower jaw xref: AAO:0000272 ! lower_jaw xref: ncithesaurus:Lower_Jaw ! Lower Jaw xref: EHDAA2:0001018 ! lower jaw region xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray176.png/200px-Gray176.png xref: EMAPA:17906 ! lower jaw xref: MESH:A02.835.232.781.324.502.632 ! mandible (also: UBERON:0001684 'mandible') xref: EFO:0003660 ! ventral mandibular arch is_a: UBERON:0011595 ! jaw region relationship: develops_from UBERON:0005867 {source="Wikipedia:Mandibular_prominence"} ! mandibular prominence property_value: external_definition "Inferior mandibular arch located on the anterior and lateral sides of the skull.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000272", date_retrieved="2012-06-20", source="AAO:LAP"} xref: SCTID:362637005 ! Entire lower jaw region property_value: homology_notes "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {external_class="VHOG:0000453", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003278 name: skeleton of lower jaw def: "A subdivision of skeleton that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] comment: in EHDAA2, this does not include the mandible; it includes the teeth and Meckel's cartilage synonym: "lower jaw skeleton" EXACT [AAO:0000274] synonym: "lower jaw" BROAD [MA:0001906] synonym: "lower jaw" BROAD [ZFA:0001273] synonym: "mandible" BROAD [ZFA:0001273] synonym: "mandibular series" RELATED [ZFA:0001273] xref: EHDAA:8005 ! skeleton xref: VHOG:0000428 ! lower jaw skeleton xref: EHDAA2:0004606 ! lower jaw skeleton xref: AAO:0000274 ! lower jaw skeleton xref: EMAPA:17910 ! skeleton of lower jaw xref: FMA:54398 ! Lower jaw xref: MA:0001906 ! lower jaw xref: TAO:0001273 ! ventral mandibular arch xref: XAO:0003084 ! lower jaw xref: ZFA:0001273 ! ventral mandibular arch intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: subdivision_of UBERON:0001710 ! lower jaw relationship: part_of UBERON:0001710 {source="EHDAA2"} ! lower jaw region relationship: overlaps UBERON:0008895 {source="VHOG-modified"} ! splanchnocranium relationship: part_of UBERON:0011156 {source="EHDAA2"} ! facial skeleton relationship: part_of UBERON:0001708 ! jaw skeleton property_value: external_definition "The ventral portion of the first pharyngeal arch, comprising the lower jaw.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001273", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass anatomical cluster (CARO:0000041) CHANGED TO: develops_from anatomical cluster (UBERON:0000477)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001273", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass anatomical cluster (CARO:0000041) CHANGED TO: overlaps anatomical cluster (UBERON:0000477)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001273", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass anatomical cluster (CARO:0000041) CHANGED TO: part_of anatomical cluster (UBERON:0000477)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001273", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass anatomical cluster (CARO:0000041) CHANGED TO: subdivision_of anatomical cluster (UBERON:0000477)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001273", date_retrieved="2012-08-14"} synonym: "mandibles" RELATED PLURAL [TAO:0001273] property_value: homology_notes "The jaw joint of all jawed vertebrates, except for mammals, involves the quadrate and articular bones, or the posterior ends of the palatoquadrate and mandibular cartilages; A correlate of the conversion of the articular and quadrate bones to the malleus and incus is that all adult mammals have a jaw joint that lies between the dentary of the lower jaw and the squamosal bone of the skull roof.[well established][VHOG]" xsd:string {external_class="VHOG:0000428", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.241 and p.101", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004742 name: dentary def: "The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians, extending to the whole lower jaw in mammals[VHOG,modified]." [VHOG:0001022] comment: Taxon notes: In lobe-finned fishes and the early fossil tetrapods, the bone homologous to the mandible of mammals is merely the largest of several bones in the lower jaw. In such animals, it is referred to as the dentary bone, and forms the body of the outer surface of the jaw. It is bordered below by a number of splenial bones, while the angle of the jaw is formed by a lower angular bone and a suprangular bone just above it. The inner surface of the jaw is lined by a prearticular bone, while the articular bone forms the articulation with the skull proper. Finally a set of three narrow coronoid bones lie above the prearticular bone. As the name implies, the majority of the teeth are attached to the dentary, but there are commonly also teeth on the coronoid bones, and sometimes on the prearticular as well. This complex primitive pattern has, however, been simplified to various degrees in the great majority of vertebrates, as bones have either fused or vanished entirely. In teleosts, only the dentary, articular, and angular bones remain, while in living amphibians, the dentary is accompanied only by the prearticular, and, in salamanders, one of the coronoids. The lower jaw of reptiles has only a single coronoid and splenial, but retains all the other primitive bones except the prearticular. synonym: "dentary bone" EXACT [ZFA:0000191] synonym: "dentale" RELATED [AAO:0000124] synonym: "os dentale" RELATED [AAO:0000124] synonym: "sur-angulaire" RELATED [AAO:0000124] xref: AAO:0000124 ! dentary xref: ZFA:0000191 ! dentary xref: VHOG:0001022 ! dentary xref: EFO:0003508 ! dentary is_a: UBERON:0008907 {source="ZFA"} ! dermal bone relationship: part_of UBERON:0003113 {source="ZFA", source="Kardong", notes="mandibular series"} ! dermatocranium relationship: part_of UBERON:0003278 {source="VHOG"} ! skeleton of lower jaw relationship: develops_from UBERON:0010336 {source="EHDAA2"} ! mandibular process mesenchyme from neural crest relationship: has_developmental_contribution_from UBERON:0003324 {source="EHDAA2-modified"} ! mesenchyme of lower jaw xref: TAO:0000191 ! dentary property_value: external_definition "Ossified element of intramembranous origin that invests the lateral margin of Meckel's cartilage thereby forming the lateral side of the mandible in anurans and salamanders (Duellman & Trueb, 1994:293). In caecilians, the dentary is part of a compound bone termed the pseudodentary.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000124", date_retrieved="2012-06-20", source="AAO:LAP"} xref: http://palaeos.com/vertebrates/bones/dermal/images/Dentary1.gif property_value: external_definition "Dermal bone that is usually the anteriormost bone of the lower jaw, and that articulates with the angular, or anguloarticular bone, posteriorly, and carries part of the mandibular sensory canal and pore openings of the mandibular sensory canal on its lateral surface. The dentary is a paired bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000191", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps dentary-anguloarticular joint (TAO:0001749)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000191", date_retrieved="2012-08-14"} synonym: "dentaries" EXACT PLURAL [TAO:0000191] property_value: external_definition "The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians. In mammals the lower jaw consists entirely of the dentary bone. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, ZFA:0000191_and_Liem_KF, p.248][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001022", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Of all these bones [dentary, splenials, coronoids, angular, surangular and prearticular], only the dentary remains in the lower jaw of a mammal.[well established][VHOG]" xsd:string {external_class="VHOG:0001022", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.248", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0001684 name: mandible def: "A dentary bone that is the only bone in one of the lateral halves of the lower jaw skeleton." [Wikipedia:Mandible, Wikipedia:Human_mandible] comment: Editor notes: consider merging with dentary - for now we make it a mammal-specific subclass. Terminology notes: 'mandible' also refers to either the upper OR lower part of the beak in birds. AO notes: Note in ZFA 'mandible' is a syn for the ventral mandibular arch, which is a portion of the 1st pharyngeal arch; however the term 'mandibular symphysis' refers to the dentary subset: uberon_slim synonym: "inferior maxillary bone" EXACT [] synonym: "lower jaw bone" BROAD SENSU [] synonym: "lower jaw" BROAD SENSU [] synonym: "mammaliam mandible" EXACT [] synonym: "mandibulla" EXACT [] synonym: "lower mandibula" NARROW SENSU [Wikipedia:Mandible] synonym: "mandibula" RELATED [BTO:0001748] synonym: "mandibular series" RELATED [ZFA:0001273] xref: EHDAA:8007 ! mandible xref: FMA:52748 ! Mandible xref: GAID:68 ! mandible xref: MA:0001487 ! mandible xref: ncithesaurus:Mandible xref: BTO:0001748 ! mandible xref: EFO:0001965 ! mandible xref: galen:Mandible ! mandible xref: EHDAA2:0001059 ! mandible xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Gray176.png/200px-Gray176.png xref: EMAPA:18290 ! mandible xref: MESH:A02.835.232.781.324.502.632 ! mandible (also: UBERON:0001710 'lower jaw region') is_a: UBERON:0004742 ! dentary is_a: UBERON:0002514 {source="EHDAA2"} ! intramembranous bone xref: SCTID:181812008 ! Entire mandible synonym: "mandibula" RELATED LATIN [Wikipedia:Human_mandible] property_value: has_relational_adjective "mandibular" xsd:string xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png xref: UMLS:C0024687 [Term] id: UBERON:0006606 name: mandibular symphysis def: "A cartilaginous joint that connects left and right mandibles/dentary bones. Mandibular symphysis is unpaired[TAO,modified]." [TAO:wd, ZFA:0005488, Wikipedia:Symphysis_menti] comment: Taxon notes: in snakes, the mandibular symphysis is composed of soft tissues, allowing independent movement of each mandible[Kardong] Editor notes: this is placed as part of lower jaw region, as in this ontology the skeleton does not include joints subset: vertebrate_core synonym: "mental symphysis" RELATED [Wikipedia:Symphysis_menti] synonym: "symphysis menti" EXACT [MA:0001490] xref: AAO:0000277 ! mandibular symphysis xref: ZFA:0005488 ! mandibular symphysis xref: FMA:75779 ! Mandibular symphysis xref: MA:0001490 ! symphysis menti is_a: UBERON:0002216 {source="FMA"} ! symphysis intersection_of: UBERON:0002213 ! cartilaginous joint intersection_of: connects UBERON:0004742 {cardinality="2"} ! dentary relationship: connects UBERON:0004742 {notes="connects adjacent mandibles"} ! dentary relationship: part_of UBERON:0001710 ! lower jaw region xref: TAO:0001851 ! mandibular symphysis synonym: "symphysis mandibulae" RELATED LATIN [Wikipedia:Symphysis_menti] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png property_value: external_definition "Joint that articulates the left and right dentary bones. Mandibular symphysis is unpaired.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001851", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "dentary symphysis" EXACT [TAO:0001851] synonym: "inter-dentary joint" EXACT [TAO:0001851] synonym: "inter-mandibular joint" EXACT [TAO:0001851] [Term] id: UBERON:0004362 name: pharyngeal arch 1 def: "First of six branchial arches that develops in fetal life during the fourth week of development.[1] It is located between the stomodeum and the first pharyngeal groove." [Wikipedia:First_pharyngeal_arch] subset: uberon_slim subset: vertebrate_core synonym: "mandibular arch" EXACT [] synonym: "first pharyngeal arch" EXACT [] synonym: "1st pharyngeal arch" EXACT [] synonym: "branchial arch 1" EXACT SENSU [] synonym: "visceral arch 1" EXACT SENSU [] synonym: "first visceral arch" EXACT SENSU [] synonym: "first branchial arch" EXACT SENSU [] synonym: "first branchial arch" EXACT SENSU [] synonym: "1st arch" RELATED [EHDAA2:0000006] xref: ZFA:0001612 ! pharyngeal arch 1 xref: XAO:0000097 ! mandibular arch xref: ncithesaurus:First_Pharyngeal_Arch ! First Pharyngeal Arch xref: VHOG:0000296 ! first pharyngeal arch xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Gray48.png/200px-Gray48.png xref: EHDAA2:0000006 ! 1st arch xref: EMAPA:16118 ! 1st arch xref: EHDAA:573 ! 1st arch is_a: UBERON:0002539 ! pharyngeal arch xref: AAO:0010364 ! mandibular arch xref: SCTID:308767008 ! Entire first branchial arch xref: TAO:0001595 ! pharyngeal arch 1 synonym: "arcus pharyngeus primus" RELATED LATIN [Wikipedia:First_pharyngeal_arch] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray48.png property_value: external_definition "The first of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010364", date_retrieved="2012-06-20", source="XAO:EJS"} property_value: pharyngeal_arch_number "1" xsd:nonNegativeInteger synonym: "1st visceral arch" RELATED [VHOG:0000296] property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0000296", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1517197 [Term] id: UBERON:0007237 ! 1st arch mandibular component name: 1st arch mandibular component comment: Editors note: relationship to Meckel's cartilage to be added xref: EHDAA2:0000031 ! 1st arch mandibular component xref: EHDAA:583 ! mandibular component xref: EMAPA:16382 ! mandibular component xref: VHOG:0000510 ! ventral pharyngeal arch 1 is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004362 {source="EHDAA2"} ! pharyngeal arch 1 synonym: "ventral pharyngeal arch 1" EXACT [VHOG:0000510] synonym: "ventral mandibular arch" RELATED [VHOG:0000510] synonym: "ventral visceral arch 1" RELATED [VHOG:0000510] property_value: homology_notes "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {external_class="VHOG:0000510", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0007238 ! 1st arch maxillary component name: 1st arch maxillary component comment: Editors note: relationship to palatoquadrate to be added xref: EHDAA2:0000038 ! 1st arch maxillary component xref: EHDAA:595 ! maxillary component xref: EMAPA:16388 ! maxillary component xref: VHOG:0000511 ! dorsal pharyngeal arch 1 (also: UBERON:0011085 'dorsal pharyngeal arch 1') is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004362 {source="EHDAA2"} ! pharyngeal arch 1 property_value: homology_notes "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {external_class="VHOG:0000511", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003066 name: pharyngeal arch 2 def: "assists in forming the side and front of the neck." [Wikipedia:Second_pharyngeal_arch] comment: In XAO, develops from visceral pouch 2 subset: uberon_slim subset: vertebrate_core synonym: "pharyngeal arch 2" EXACT [] synonym: "branchial arch 2" EXACT SENSU [] synonym: "visceral arch 2" EXACT SENSU [] synonym: "second pharyngeal arch" EXACT [] synonym: "2nd pharyngeal arch" EXACT [] synonym: "branchial arch 2" EXACT SENSU [] synonym: "visceral arch 2" EXACT SENSU [] synonym: "second visceral arch" EXACT SENSU [] synonym: "second branchial arch" EXACT SENSU [] synonym: "second branchial arch" EXACT SENSU [] synonym: "hyoid bars" RELATED [] synonym: "2nd arch" RELATED [EHDAA2:0000050] synonym: "hyoid arch" EXACT [XAO:0000098] synonym: "arcus pharyngeus secundus" EXACT LATIN [Wikipedia:Second_pharyngeal_arch] xref: ZFA:0001611 ! pharyngeal arch 2 xref: XAO:0000098 ! hyoid arch xref: ncithesaurus:Second_Pharyngeal_Arch ! Second Pharyngeal Arch xref: VHOG:0000297 ! second pharyngeal arch xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8b/Gray41.png/200px-Gray41.png xref: EHDAA2:0000050 ! 2nd arch xref: EMAPA:16272 ! 2nd arch xref: EHDAA:611 ! 2nd arch is_a: UBERON:0002539 ! pharyngeal arch xref: AAO:0010363 ! hyoid arch xref: SCTID:308768003 ! Entire second branchial arch xref: TAO:0001596 ! pharyngeal arch 2 xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png property_value: external_definition "The second of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010363", date_retrieved="2012-06-20", source="XAO:EJS"} property_value: pharyngeal_arch_number "2" xsd:nonNegativeInteger synonym: "2nd visceral arch" RELATED [VHOG:0000297] synonym: "pharyngeal arches 2" RELATED [VHOG:0000297] property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0000297", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005884 name: hyoid arch skeleton comment: AO notes: it's not clear where AAO:'hyobranchial skeleton' belongs synonym: "hyoid arch skeleton" EXACT [ZFA:0001276] synonym: "pharyngeal arch 2 skeleton" EXACT [ZFA:0001276] synonym: "hyoid arch" RELATED INCONSISTENT [TAO:0001276] synonym: "visceral arch 2" RELATED INCONSISTENT [TAO:0001276] synonym: "hyoid bars" NARROW [TAO:0001276] xref: ZFA:0001276 ! pharyngeal arch 2 skeleton xref: XAO:0003177 ! hyoid arch skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: subdivision_of UBERON:0003066 ! hyoid arch relationship: part_of UBERON:0008895 {source="ZFA"} ! splanchnocranium relationship: part_of UBERON:0011156 {source="cjm"} ! facial skeleton relationship: part_of UBERON:0003066 {source="ZFA"} ! pharyngeal arch 2 relationship: part_of UBERON:0008895 ! pharyngeal arch skeleton xref: AAO:0010370 ! hyoid arch skeleton xref: AAO:0000665 ! hyobranchial skeleton xref: TAO:0001276 ! hyoid arch synonym: "hyal@fr" RELATED [TAO:0001276] synonym: "hyocïde@fr" RELATED [TAO:0001276] def: "A subdivision of skeleton that subdivision_of a pharyngeal arch 2." [OBOL:automatic] [Term] id: UBERON:0011152 name: dorsal hyoid arch skeleton synonym: "dorsal pharyngeal arch 2 skeleton" EXACT [] synonym: "dorsal visceral arch 2" EXACT [ZFA:0001401] synonym: "dorsal hyoid arch" EXACT [ZFA:0001401] is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0005884 {source="AAO"} ! hyoid arch skeleton xref: AAO:0010371 ! dorsal hyoid arch skeleton xref: XAO:0003178 ! dorsal hyoid arch skeleton xref: ZFA:0001401 ! dorsal hyoid arch xref: TAO:0001401 ! dorsal hyoid arch [Term] id: UBERON:0011153 name: ventral hyoid arch skeleton synonym: "ventral pharyngeal arch 2 skeleton" EXACT [] synonym: "ventral visceral arch 2" EXACT [ZFA:0001402] synonym: "ventral hyoid arch" EXACT [ZFA:0001402] is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0005884 {source="AAO"} ! hyoid arch skeleton xref: AAO:0010372 ! ventral hyoid arch skeleton xref: XAO:0003179 ! ventral hyoid arch skeleton xref: ZFA:0001402 ! ventral hyoid arch xref: TAO:0001402 ! ventral hyoid arch xref: EFO:0003684 ! ventral hyoid arch [Term] id: UBERON:0003114 name: pharyngeal arch 3 def: "The third branchial arch contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus." [MP:0006339] comment: in XAO, called branchial arch 1 and df VP3 subset: vertebrate_core synonym: "3rd pharyngeal arch" EXACT [] synonym: "third pharyngeal arch" EXACT [] synonym: "third visceral arch" EXACT [] synonym: "visceral arch 3" EXACT [] synonym: "first branchial arch" RELATED SENSU [ZFA:0001606] synonym: "branchial arch 1" RELATED SENSU [ZFA:0001606, AAO:0010365] synonym: "first gill arch" EXACT SENSU [ZFA:0001606] synonym: "gill arch 1" EXACT SENSU [ZFA:0001606] synonym: "3rd arch" RELATED [EHDAA2:0000069] xref: ZFA:0001606 ! pharyngeal arch 3 xref: XAO:0000447 ! branchial arch 1 xref: VHOG:0000298 ! third pharyngeal arch xref: EHDAA2:0000069 ! 3rd arch xref: EMAPA:16399 ! 3rd arch xref: EHDAA:1080 ! 3rd arch xref: AAO:0010365 ! branchial arch 1 is_a: UBERON:0002539 ! pharyngeal arch xref: SCTID:308769006 ! Entire third branchial arch xref: TAO:0001598 ! gill arch 1 property_value: external_definition "The most anterior, or first, pharygeal/branchial arch, composed of the mandibular process, forming the posterior border of the stomodeum, and the maxillary process anterior to the stomodeum, contains the first aortic arch.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010365", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: pharyngeal_arch_number "3" xsd:nonNegativeInteger synonym: "3rd visceral arch" RELATED [VHOG:0000298] property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0000298", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003115 name: pharyngeal arch 4 def: "contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus" [MP:0006340] comment: in XAO, called branchial arch 2 and df VP4 subset: uberon_slim subset: vertebrate_core synonym: "4th pharyngeal arch" EXACT [] synonym: "fourth pharyngeal arch" EXACT [] synonym: "4th branchial arch" EXACT SENSU [] synonym: "4th visceral arch" EXACT [] synonym: "visceral arch 4" EXACT [] synonym: "second branchial arch" RELATED SENSU [ZFA:0001607] synonym: "branchial arch 2" RELATED SENSU [ZFA:0001607, AAO:0010366] synonym: "second gill arch" EXACT SENSU [ZFA:0001607] synonym: "gill arch 2" EXACT SENSU [ZFA:0001607] synonym: "4th arch" RELATED [EHDAA2:0000086] xref: ZFA:0001607 ! pharyngeal arch 4 xref: XAO:0000449 ! branchial arch 2 xref: VHOG:0000299 ! fourth pharyngeal arch xref: EHDAA2:0000086 ! 4th arch xref: EMAPA:16760 ! 4th arch xref: EHDAA:1663 ! 4th arch xref: AAO:0010366 ! branchial arch 2 is_a: UBERON:0002539 ! pharyngeal arch xref: SCTID:308770007 ! Entire fourth branchial arch xref: TAO:0001599 ! gill arch 2 property_value: external_definition "The second pharyngeal/branchial arch; arises as a thickening of the pharygeal wall between the first and second branchial clefts; contains the second aortic arch; forms part of the hyoid bone, tongue and facial musculature.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010366", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: pharyngeal_arch_number "4" xsd:nonNegativeInteger synonym: "fourth visceral arch" RELATED [VHOG:0000299] property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0000299", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003116 name: pharyngeal arch 5 comment: A fifth arch never establishes itself in amniotes // in XAO, called branchial arch 3 and df VP5 synonym: "branchial arch 3" RELATED [ZFA:0001608] synonym: "fifth visceral arch" EXACT [XAO:0000451] synonym: "gill arch 3" EXACT [ZFA:0001608] synonym: "third branchial arch" RELATED SENSU [XAO:0000451] synonym: "branchial arch 3" RELATED SENSU [XAO:0000451, AAO:0010367] synonym: "visceral arch 5" EXACT [ZFA:0001608] xref: XAO:0000451 ! branchial arch 3 xref: ZFA:0001608 ! pharyngeal arch 5 xref: VHOG:0001204 ! fifth pharyngeal arch xref: AAO:0010367 ! branchial arch 3 is_a: UBERON:0002539 ! pharyngeal arch xref: SCTID:308771006 ! Entire fifth branchial arch xref: TAO:0001600 ! gill arch 3 property_value: external_definition "The third in a series of paired bars in the wall of the pharynx, within which are formed the third aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010367", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: pharyngeal_arch_number "5" xsd:nonNegativeInteger synonym: "5th pharyngeal arch" RELATED [VHOG:0001204] synonym: "5th visceral arch" RELATED [VHOG:0001204] synonym: "fifth pharyngeal arch" RELATED [VHOG:0001204] property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0001204", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M\, Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003117 name: pharyngeal arch 6 alt_id: UBERON:0004349 def: "The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles" [MP:0006347] synonym: "sixth branchial arch" EXACT [] synonym: "branchial arch 4" RELATED SENSU [ZFA:0001609, AAO:0010368] synonym: "fourth branchial arch" RELATED SENSU [] synonym: "gill arch 4" EXACT [ZFA:0001609] synonym: "sixth visceral arch" RELATED [XAO:0000453] synonym: "visceral arch 6" EXACT [ZFA:0001609] synonym: "6th arch" EXACT [EHDAA2:0004075] xref: XAO:0000453 ! branchial arch 4 xref: ZFA:0001609 ! pharyngeal arch 6 xref: VHOG:0001205 ! sixth pharyngeal arch xref: AAO:0010368 ! branchial arch 4 is_a: UBERON:0002539 ! pharyngeal arch xref: SCTID:308772004 ! Entire sixth branchial arch xref: EHDAA2:0004075 ! 6th arch xref: TAO:0001601 ! gill arch 4 property_value: external_definition "The forth in a series of paired bars in the wall of the pharynx, within which are formed the forth aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010368", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: pharyngeal_arch_number "6" xsd:nonNegativeInteger synonym: "6th pharyngeal arch" RELATED [VHOG:0001205] synonym: "6th visceral arch" RELATED [VHOG:0001205] synonym: "sixth pharyngeal arch" RELATED [VHOG:0001205] property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0001205", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M\, Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0011087 name: pharyngeal arch 7 synonym: "branchial arch 5" RELATED [ZFA:0001610] synonym: "gill arch 5" EXACT [ZFA:0001610] synonym: "visceral arch 7" EXACT [ZFA:0001610] xref: TAO:0001602 ! gill arch 5 is_a: UBERON:0008896 {source="ZFA"} ! pharyngeal arch 3-7 xref: ZFA:0001610 ! pharyngeal arch 7 xref: TAO:0001602 ! gill arch 5 property_value: pharyngeal_arch_number "7" xsd:nonNegativeInteger [Term] id: UBERON:0011638 name: pharyngeal arch 8 synonym: "branchial arch 6" RELATED [] synonym: "gill arch 6" EXACT [] synonym: "visceral arch 8" EXACT [] is_a: UBERON:0008896 {source="TAO"} ! post-hyoid pharyngeal arch property_value: pharyngeal_arch_number "8" xsd:nonNegativeInteger [Term] id: UBERON:0008896 name: post-hyoid pharyngeal arch def: "A pharyngeal arch that is posterior to the hyoid arch. i.e. any pharyngeal arch with a number 3 or higher." [UBERON:cjm] synonym: "branchial arch" EXACT [ZFA:0001613] synonym: "branchial arches" EXACT PLURAL [ZFA:0001613] synonym: "gill bar" RELATED [UBERON:cjm] synonym: "branchial bar" EXACT [ZFA:0001613] synonym: "branchial bars" EXACT PLURAL [ZFA:0001613] synonym: "gill arch" EXACT [ZFA:0001613] synonym: "gill arches 1-5" EXACT [ZFA:0001613] synonym: "visceral arches 3-7" EXACT [ZFA:0001613] synonym: "pharyngeal arch 3-7" EXACT [ZFA:0001613] xref: TAO:0001597 ! gill arch xref: XAO:0000099 ! branchial arch xref: AAO:0010362 ! branchial arch is_a: UBERON:0002539 {source="ZFA"} ! pharyngeal arch xref: ZFA:0001613 ! pharyngeal arch 3-7 xref: SCTID:308766004 ! Entire branchial arch (also: UBERON:0002539 'pharyngeal arch') xref: BTO:0002152 ! gill arch property_value: external_definition "Posterior-most stream of cranial neural crest, which sub-divides during migration.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010362", date_retrieved="2012-06-20", source="AAO:EJS"} xref: EFO:0003694 ! pharyngeal arch 3-7 [Term] id: UBERON:0005886 name: post-hyoid pharyngeal arch skeleton comment: AO notes: XAO class belongs here, as it clearly refers to arches 3-7 synonym: "branchial arch skeleton" RELATED SENSU [XAO:0003180] synonym: "gill arch skeleton" RELATED [XAO:0003180] synonym: "visceral arch skeleton" RELATED [XAO:0003180] synonym: "gill arch 1-5 skeleton" EXACT [TAO:0000095] synonym: "pharyngeal arch 3-7 skeleton" EXACT [ZFA:0000095] xref: ZFA:0000095 ! pharyngeal arch 3-7 skeleton xref: XAO:0003180 ! branchial arch skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: subdivision_of UBERON:0008896 ! pharyngeal arch 3-7 relationship: part_of UBERON:0008895 {source="ZFA"} ! splanchnocranium relationship: part_of UBERON:0008896 {source="ZFA"} ! pharyngeal arch 3-7 xref: TAO:0000095 ! gill arch 1-5 skeleton xref: SCTID:346439007 ! Entire gill arch skeleton property_value: external_definition "Skeletal and cartilage elements of the gill arches; the last five of the set of seven pharyngeal arches; the numbering system can be confusing; generally branchial arch #1 is the first gill arch, or the third pharyngeal arch, but some authors do not follow this convention. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000095", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass anatomical cluster (CARO:0000041) CHANGED TO: part_of anatomical cluster (UBERON:0000477)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000095", date_retrieved="2012-08-14"} def: "A subdivision of skeleton that subdivision_of a post-hyoid pharyngeal arch." [OBOL:automatic] [Term] id: UBERON:0001508 name: arch of aorta def: "begins at the level of the upper border of the second sternocostal articulation of the right side, and runs at first upward, backward, and to the left in front of the trachea; it is then directed backward on the left side of the trachea and finally passes downward on the left side of the body of the fourth thoracic vertebra, at the lower border of which it becomes continuous with the descending aorta[WP]." [Wikipedia:Arch_of_aorta] comment: Usage notes: Do not confuse with aortic arch; check EHDAA2. Taxon notes: birds have right aortic arch, mammals left. subset: uberon_slim synonym: "aortic arch" RELATED [FMA:3768] synonym: "thoracic aorta" RELATED [GAID:471] xref: MA:0000475 ! arch of aorta xref: FMA:3768 ! arch of aorta xref: GAID:471 ! thoracic aorta (also: UBERON:0001515 'thoracic aorta') xref: EFO:0002526 ! aortic arch xref: VHOG:0001196 ! arch of aorta xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Gray506.svg/200px-Gray506.svg.png xref: BTO:0000157 ! aorta thoracica (also: UBERON:0001515 'thoracic aorta') xref: EMAPA:17613 ! arch of aorta of arterial system of cardiovascular system of organ system xref: EMAPA:18602 ! arch of aorta of aorta xref: EHDAA2:0000132 ! aortic arch is_a: UBERON:0005800 ! segment of aorta relationship: part_of UBERON:0001515 ! thoracic aorta relationship: develops_from UBERON:0003121 ! aortic arch 4 relationship: has_developmental_contribution_from UBERON:0005432 ! aortic sac relationship: has_developmental_contribution_from UBERON:0005613 ! left dorsal aorta synonym: "arcus aortae" EXACT LATIN [FMA:TA, FMA:3768] xref: SCTID:181300001 ! Entire aortic arch property_value: external_definition "The curving portion between the ascending aorta and the descending aorta, giving rise to the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001196", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/arch+of+aorta", source="http://bgee.unil.ch/"} property_value: homology_notes "The double systemic arch arches (left and right) present in amphibians and reptiles become reduced to a single systemic arch - the right in birds, the left in mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0001196", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.460 and p.461 Figure 12.20", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004363 ! aortic arch name: aortic arch alt_id: UBERON:0004342 def: "One of a series of paired embryological vascular structures which give rise to several major arteries." [Wikipedia:Aortic_arches, MP:0002672] comment: Usage notes: Do not confuse with arch of aorta. Editor notes: add specific artery derivatives. Development notes: The third, fourth, and sixth arches, along with the seventh intersegmental arteries and the left dorsal aorta, are the primary contributors to the normal aortic arch and its major thoracic branches. Taxon notes: Number varies - Lampreys have 8, hagfishes 15; only up to 6 appear in embryonic development in most gnathostome fishes and all tetrapods subset: uberon_slim subset: vertebrate_core synonym: "aortic arches" EXACT PLURAL [ZFA:0005004] synonym: "branchial arch artery" EXACT [EMAPA:16684] synonym: "embryonic aortic arch artery" EXACT [EMAPA:16684, MP:0002672] synonym: "branchial aortic arches " EXACT PLURAL [ZFIN:ZDB-PUB-080512-6] xref: XAO:0000341 ! aortic arch xref: EHDAA:7327 ! aortic arch xref: VHOG:0000122 ! aortic arch xref: ZFA:0005004 ! aortic arch xref: ncithesaurus:Aortic_Arch ! Aortic Arch xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Gray473.png/200px-Gray473.png xref: EMAPA:16684 ! branchial arch artery xref: EHDAA2:0000186 ! branchial arch artery xref: EHDAA:398 ! branchial arch artery xref: EFO:0003695 ! aortic arch xref: AAO:0010414 ! aortic arch is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0001637 {source="ZFA"} ! artery relationship: part_of UBERON:0000922 ! embryo relationship: develops_into UBERON:0001637 ! artery relationship: part_of UBERON:0008814 ! pharyngeal system relationship: part_of UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0007303 {source="ZFA"} ! pharyngeal vasculature relationship: has_developmental_contribution_from UBERON:0002342 {notes="abduced from EHDAA2"} ! neural crest xref: AAO:0010414 ! aortic arch xref: TAO:0005004 ! aortic arch synonym: "aa. arcuum pharyngeorum" RELATED LATIN [Wikipedia:Aortic_arches] xref: http://upload.wikimedia.org/wikipedia/commons/8/84/Gray473.png synonym: "pharyngeal arch artery" RELATED [VHOG:0000122] property_value: external_definition "Paired vessels arching from the ventral to the dorsal aorta through the pharyngeal arches. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000122", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/aortic+arches", source="http://bgee.unil.ch/"} property_value: homology_notes "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {external_class="VHOG:0000122", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0003489 [Term] id: UBERON:0003118 name: aortic arch 1 alt_id: UBERON:0004371 def: "the vessels formed within the first pair of branchial arches in embryogenesis" [MP:0006356] comment: ZFA: The paired aortic arch 1 arteries branch off of the ventral aorta, and empty into the right and left lateral dorsal aortas. // Disappears early in development in tetrapods subset: vertebrate_core synonym: "AA1" EXACT [ZFA:0005005] synonym: "first aortic arch" EXACT [XAO:0000342] synonym: "mandibular aortic arch" EXACT [ZFA:0005005] synonym: "1st arch artery" EXACT [EMAPA:16685] synonym: "first branchial arch artery" EXACT [] xref: VHOG:0000149 ! first aortic arch xref: TAO:0005005 ! aortic arch 1 xref: XAO:0000342 ! aortic arch 1 xref: ZFA:0005005 ! aortic arch 1 xref: EHDAA2:0000007 ! 1st arch artery xref: EMAPA:16685 ! 1st arch artery intersection_of: UBERON:0004363 ! aortic arch intersection_of: part_of UBERON:0004362 ! pharyngeal arch 1 xref: AAO:0010415 ! aortic arch 1 xref: SCTID:308774003 ! Entire first aortic arch xref: EMAPA:16202 ! 1st arch artery [Term] id: UBERON:0003119 ! aortic arch 2 name: aortic arch 2 alt_id: UBERON:0004372 def: "The first and second arches disappear early, but the dorsal end of the second gives origin to the stapedial artery, a vessel which atrophies in humans but persists in some mammals. It passes through the ring of the stapes and divides into supraorbital, infraorbital, and mandibular branches which follow the three divisions of the trigeminal nerve. The infraorbital and mandibular arise from a common stem, the terminal part of which anastomoses with the external carotid. On the obliteration of the stapedial artery this anastomosis enlarges and forms the internal maxillary artery, and the branches of the stapedial artery are now branches of this vessel. The common stem of the infraorbital and mandibular branches passes between the two roots of the auriculotemporal nerve and becomes the middle meningeal artery; the original supraorbital branch of the stapedial is represented by the orbital twigs of the middle meningeal[WP]." [Wikipedia:Aortic_arches#Arches_1_and_2] subset: vertebrate_core synonym: "AA2" EXACT [ZFA:0005006] synonym: "hyoid aortic arch" EXACT [ZFA:0005006] synonym: "second aortic arch" EXACT [XAO:0000343] synonym: "2nd arch artery" EXACT [EHDAA2:0000051] synonym: "second branchial arch artery" EXACT [] xref: EHDAA2:0000051 ! 2nd arch artery xref: EMAPA:16686 ! 2nd arch artery xref: VHOG:0000148 ! second aortic arch xref: XAO:0000343 ! aortic arch 2 xref: ZFA:0005006 ! aortic arch 2 intersection_of: UBERON:0004363 ! aortic arch intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 xref: AAO:0010418 ! aortic arch 2 xref: SCTID:308775002 ! Entire second aortic arch xref: EMAPA:16203 ! 2nd arch artery xref: TAO:0005006 ! aortic arch 2 property_value: external_definition "The second in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 2 that is part of hyoid arch.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010418", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} [Term] id: UBERON:0003120 name: aortic arch 3 alt_id: UBERON:0004352 def: "The third aortic arch constitutes the commencement of the internal carotid artery, and is therefore named the carotid arch[WP]." [Wikipedia:Aortic_arches#Arch_3] subset: vertebrate_core synonym: "AA3" EXACT [ZFA:0005007] synonym: "third aortic arch" EXACT [XAO:0000344] synonym: "carotid arch" EXACT [Wikipedia:Aortic_arches#Arch_3] synonym: "3rd arch artery" EXACT [EHDAA2:0000070] synonym: "third branchial arch artery" EXACT [] xref: EHDAA2:0000070 ! 3rd arch artery xref: EMAPA:16687 ! 3rd arch artery xref: VHOG:0000147 ! third aortic arch xref: XAO:0000344 ! aortic arch 3 xref: ZFA:0005007 ! aortic arch 3 intersection_of: UBERON:0004363 ! aortic arch intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 xref: AAO:0010419 ! aortic arch 3 xref: SCTID:308776001 ! Entire third aortic arch xref: TAO:0005007 ! aortic arch 3 property_value: external_definition "The third in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 3 lies within the 3rd branchial arch and branches directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010419", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: external_definition "Aortic arches 3 and 4 are not remodeled but are retained largely intact as the branchial arteries providing circulation through the gills. These areches are direct branches from the ventral aorta to the lateral dorsal aorta. Isogai et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005007", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0003121 ! aortic arch 4 name: aortic arch 4 alt_id: UBERON:0004350 def: "The fourth right arch forms the right subclavian as far as the origin of its internal mammary branch; while the fourth left arch constitutes the arch of the aorta between the origin of the left carotid artery and the termination of the ductus arteriosus[WP]." [Wikipedia:Aortic_arches#Arch_4] comment: Development notes: Normally, the left fourth arch becomes the aortic arch, the right fourth arch contributes to the innominate artery[http://emedicine.medscape.com/article/899609-overview] in birds it is the right fourth arch which forms the permanent aorta // proximal right subclavian subset: vertebrate_core synonym: "AA4" EXACT [ZFA:0005008] synonym: "fourth aortic arch" EXACT [XAO:0000355] synonym: "4th arch artery" EXACT [EHDAA2:0000087] synonym: "fourth branchial arch artery" EXACT [] synonym: "systemic arch" RELATED [XAO:0000355, ISBN10:0073040584] xref: VHOG:0000146 ! fourth aortic arch xref: XAO:0000355 ! aortic arch 4 xref: ZFA:0005008 ! aortic arch 4 xref: EHDAA2:0000087 ! 4th arch artery xref: EMAPA:17004 ! 4th arch artery intersection_of: UBERON:0004363 ! aortic arch intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 xref: AAO:0010420 ! aortic arch 4 xref: SCTID:308777005 ! Entire fourth aortic arch xref: TAO:0005008 ! aortic arch 4 property_value: external_definition "The forth in a series paired arterial connections between the dorsal and ventral aortae, lies within the 4th branchial arch. The paired aortic arch 4 arteries branch directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010420", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: external_definition "Aortic arches 3 and 4 are not remodeled but are retained largely intact as the branchial arteries providing circulation through the gills. These areches are direct branches from the ventral aorta to the lateral dorsal aorta. Isogai et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005008", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0003122 name: aortic arch 5 def: "The fifth arch disappears on both sides[WP]." [Wikipedia:Aortic_arches#Arch_5] subset: vertebrate_core synonym: "AA5" EXACT [ZFA:0005009] synonym: "fifth aortic arch" EXACT [XAO:0000352] xref: VHOG:0000145 ! fifth aortic arch xref: XAO:0000352 ! aortic arch 5 xref: ZFA:0005009 ! aortic arch 5 intersection_of: UBERON:0004363 ! aortic arch intersection_of: part_of UBERON:0003116 ! pharyngeal arch 5 xref: AAO:0010421 ! aortic arch 5 xref: SCTID:308778000 ! Entire fifth aortic arch xref: TAO:0005009 ! aortic arch 5 property_value: external_definition "The fifth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 5 artery is paired and has a common trunk with aortic arch 6 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. Aortic arches 5 and 6 supply the trunk and tail with oxygenated blood.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010421", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: external_definition "The fifth and sixth arches, which come on-line at approximately 2.5 dpf, have a common trunk from the ventral aorta and drain to the midline dorsal aorta via an independent route. The fifth and sixth aortic arches supply the trunk and tail with oxigenated blood. Isogai et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005009", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0003123 name: aortic arch 6 alt_id: UBERON:0004351 def: "The sixth right arch disappears; the sixth left arch gives off the pulmonary arteries and forms the ductus arteriosus; this duct remains pervious during the whole of fetal life, but then closes within the first few days after birth due to increased O2 concentration. Oxygen concentration causes the production of bradykinin which causes the ductus to constrict occluding all flow. Within 1-3 months, the ductus is obliterated and becomes the ligamentum arteriosus. His showed that in the early embryo the right and left arches each gives a branch to the lungs, but that later both pulmonary arteries take origin from the left arch[WP]." [Wikipedia:Aortic_arches#Arch_6] comment: Development notes: the distal left sixth arch becomes the ductus arteriosus, the proximal sixth arches bilaterally contribute to the proximal branch pulmonary arteries[http://emedicine.medscape.com/article/899609-overview] subset: vertebrate_core synonym: "AA6" EXACT [ZFA:0005016] synonym: "sixth aortic arch" EXACT [XAO:0000353] synonym: "6th arch artery" EXACT [EMAPA:17005] synonym: "sixth branchial arch artery" EXACT [] synonym: "pulmonary arch" RELATED [ISBN10:0073040584] xref: VHOG:0000144 ! sixth aortic arch xref: XAO:0000353 ! aortic arch 6 xref: ZFA:0005016 ! aortic arch 6 xref: EMAPA:17005 ! 6th arch artery xref: EHDAA2:0000102 ! 6th arch artery intersection_of: UBERON:0004363 ! aortic arch intersection_of: part_of UBERON:0003117 ! pharyngeal arch 6 xref: AAO:0010422 ! aortic arch 6 xref: SCTID:308779008 ! Entire sixth aortic arch xref: TAO:0005016 ! aortic arch 6 property_value: external_definition "The sixth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 6 artery is paired and has a common trunk with aortic arch 5 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. It forms part of the pulmonary arteries, and in the later embryo, the ductus arteriosis. Aortic arches 5 and 6 together supply the trunk and tail with oxygenated blood.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010422", date_retrieved="2012-06-20", source="ISBN:0-02-377110-0"} property_value: external_definition "The fifth and sixth arches, which come on-line at approximately 2.5 dpf, have a common trunk from the ventral aorta and drain to the midline dorsal aorta via an independent route. The fifth and sixth aortic arches supply the trunk and tail with oxigenated blood. Isogai et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005016", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0006345 name: stapedial artery def: "A small artery that passes through the ring of the stapes; while the stapedial artery is a temporary artery thought to disappear at late embryonic stage in humans, the mouse stapedial artery is complete by E13 and persists into adulthood[MP]." [MP:0004665] synonym: "stapedial" RELATED [EHDAA2:0001908] synonym: "stapedial artery temporary" EXACT [EHDAA2:0001908] xref: MA:0002044 ! stapedial artery xref: EMAPA:17313 ! stapedial artery xref: EHDAA2:0001908 ! stapedial artery temporary is_a: UBERON:0001637 {source="EHDAA2"} ! artery relationship: develops_from UBERON:0003119 {source="EHDAA2"} ! aortic arch 2 relationship: part_of UBERON:0001756 {source="EHDAA2"} ! middle ear relationship: existence_ends_during UBERON:0000068 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="MP"} ! embryo stage xref: ncithesaurus:Stapedial_Artery ! Stapedial Artery xref: SCTID:361518009 ! Stapedial artery xref: UMLS:C1284048 [Term] id: UBERON:0005608 ! hyoid artery name: hyoid artery def: "The second arch becomes the hyoid artery, which is prominent in early development and normally persists as the caroticotympanic branch of the ICA[Padget]" [http://www.ajnr.org/cgi/content/full/21/3/572] xref: MA:0001969 ! hyoid artery xref: RETIRED_EHDAA2:0000792 ! hyoid artery xref: EMAPA:17308 ! hyoid artery xref: VHOG:0001409 ! hyoid artery xref: EHDAA:3342 ! hyoid artery is_a: UBERON:0001637 ! artery relationship: develops_from UBERON:0003119 {source="http://www.ajnr.org/cgi/content/full/21/3/572"} ! aortic arch 2 [Term] id: UBERON:0007693 name: caroticotympanic artery def: "The caroticotympanic branch (tympanic branch) is small; it enters the tympanic cavity through a minute foramen in the carotid canal, and anastomoses with the anterior tympanic branch of the internal maxillary, and with the stylomastoid artery." [Wikipedia:Caroticotympanic_arteries] synonym: "caroticotympanic branch" RELATED [Wikipedia:Caroticotympanic_arteries] xref: FMA:49828 ! caroticotympanic artery is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0001532 {source="FMA"} ! internal carotid artery relationship: develops_from UBERON:0005608 {source="http://www.ajnr.org/cgi/content/full/21/3/572"} ! hyoid artery xref: SCTID:148470005 ! Entire caroticotympanic artery synonym: "arteriae caroticotympanicae, ramus caroticotympanicus" RELATED LATIN [Wikipedia:Caroticotympanic_arteries] [Term] id: UBERON:0010333 name: extraembryonic membrane mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005631 ! extraembryonic membrane relationship: develops_from UBERON:0005728 {source="EHDAA2-abduced"} ! extraembryonic mesoderm def: "Mesenchyme that is part of a extraembryonic membrane." [OBOL:automatic] [Term] id: UBERON:0003124 name: chorion def: "The chorion is one of the membranes that exists during pregnancy between the developing fetus and mother. It is formed by extraembryonic mesoderm and the two layers of trophoblast and surrounds the embryo and other membranes. The chorionic villi emerge from the chorion, invade the endometrium, and allow transfer of nutrients from maternal blood to fetal blood." [Wikipedia:Chorion] comment: Development notes: Extra-embryonic ectoderm[PMID:19829370]. Taxon notes: The chorion of placentals is bilaminar as in reptiles and birds, but forms from the trophoblast and includes the ajdacent mesodermal layer [ISBN10:0073040584 "Vertebrates\, Kardong"]. subset: uberon_slim synonym: "fetal chorion" EXACT [] synonym: "embryonic chorion" EXACT [] synonym: "chorion (vertebrates)" EXACT [] synonym: "chorion frondosum" RELATED [Wikipedia:Chorion] synonym: "chorionic sac" RELATED [Wikipedia:Chorion] xref: BTO:0000252 xref: EHDAA:150 ! chorion xref: FMA:80224 ! Chorion xref: GAID:1299 ! chorion xref: VHOG:0000200 ! chorion xref: ncithesaurus:Chorion ! Chorion xref: ncithesaurus:Chorionic_Sac ! chorionic sac xref: EHDAA2:0000245 ! chorion xref: EMAPA:16112 ! chorion xref: MESH:A16.254.403.473 ! chorion xref: EV:0100121 ! chorion xref: EFO:0002780 ! chorion is_a: UBERON:0005631 ! extraembryonic membrane relationship: adjacent_to UBERON:0000922 ! embryo relationship: has_part UBERON:0003265 ! chorionic mesoderm relationship: has_part UBERON:0003374 ! chorionic ectoderm relationship: develops_from UBERON:0005971 {source="ISBN10:0073040584"} ! amniotic fold xref: http://upload.wikimedia.org/wikipedia/commons/5/51/Gray24.png property_value: external_definition "The outer membrane enclosing the embryo in reptiles, birds, and mammals. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000200", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/chorion", source="http://bgee.unil.ch/"} property_value: homology_notes "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {external_class="VHOG:0000200", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.187", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "chorionic" xsd:string property_value: external_definition "The outer membrane of the two membranes enclosing the embryo in reptiles, birds, and mammals. In placental mammals it contributes to the development of the placenta[BTO:0000252]." xsd:string {source="BTO:0000252"} xref: UMLS:C0008503 xref: UMLS:C1516505 [Term] id: UBERON:0000305 name: amnion def: "A membrane building the amniotic sac that surrounds and protects an embryo. It is developed in reptiles, birds, and mammals, which are hence called “Amniota”; but not in amphibians and fish (Ichthyopsida), which are consequently termed “Anamniota”. The primary function of this is the protection of the embryo for its development. It stems from parts of the mesoderm on the outer side and the ectoderm on the inner side[WP]." [Wikipedia:Amnion] xref: BTO:0000065 xref: FMA:80223 ! Amnion xref: VHOG:0000721 ! amnion xref: ncithesaurus:Amnion xref: GAID:1298 ! amnion xref: EHDAA:136 ! amnion xref: EHDAA2:0000116 ! amnion xref: EMAPA:16109 ! amnion xref: MESH:A16.254.403.277 ! amnion xref: EV:0100122 ! amnion is_a: UBERON:0005631 ! extraembryonic membrane relationship: surrounds UBERON:0000922 ! embryo relationship: has_developmental_contribution_from UBERON:0004871 {source="ISBN10:0073040584-table5.4"} ! somatic layer of lateral plate mesoderm relationship: has_developmental_contribution_from UBERON:0000924 {source="ISBN10:0073040584-table5.4"} ! ectoderm relationship: develops_from UBERON:0005971 {source="ISBN10:0073040584"} ! amniotic fold relationship: has_part UBERON:0003254 ! amniotic ectoderm relationship: has_part UBERON:0003262 ! amniotic mesoderm xref: SCTID:181457005 ! Entire amnion xref: http://upload.wikimedia.org/wikipedia/commons/e/e7/Gray14.png property_value: external_definition "A thin but tough extraembryonic membrane of reptiles, birds and mammals that lines the chorion and contains the fEtus and the amniotic fluid around it. [Biology_Online][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000721", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {external_class="VHOG:0000721", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.187", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "amniotic" xsd:string xref: UMLS:C0002630 [Term] id: UBERON:0003254 alt_id: UBERON:0008359 name: amniotic ectoderm comment: Editor note: we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion. synonym: "amnionic ectoderm" EXACT [ISBN:9780878932504] synonym: "amnion ectoderm" EXACT [OBOL:automatic] synonym: "amnion ectoderm" EXACT [EHDAA2:0000117] synonym: "amnion epithelium" RELATED [BTO:0000897] xref: BTO:0000897 ! amnion epithelium xref: EHDAA:138 ! ectoderm xref: VHOG:0000621 ! amnion ectoderm xref: EHDAA2:0000117 ! amnion ectoderm xref: EMAPA:16110 ! ectoderm of amnion is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0002532 {source="ISBN:9780878932504", source="EHDAA2-via-amnioblasts"} ! epiblast relationship: part_of UBERON:0000305 {source="EHDAA2"} ! amnion [Term] id: UBERON:0003262 alt_id: UBERON:0003411 name: amniotic mesoderm comment: Editor note: we make the germ layer relationship develops_from, as currently the germ layers are declared to be purely embryonic. TODO - check. WP:Amnion - In the human embryo the earliest stages of the formation of the amnion have not been observed; in the youngest embryo which has been studied the amnion was already present as a closed sac, and appears in the inner cell-mass as a cavity. This cavity is roofed in by a single stratum of flattened, ectodermal cells, the amniotic ectoderm, and its floor consists of the prismatic ectoderm of the embryonic disk—the continuity between the roof and floor being established at the margin of the embryonic disk. Outside the amniotic ectoderm is a thin layer of mesoderm, which is continuous with that of the somatopleure and is connected by the body-stalk with the mesodermal lining of the chorion. synonym: "amnion mesoderm" EXACT [OBOL:automatic] synonym: "amnion mesenchyme" EXACT [EHDAA2:0000118] synonym: "mesenchyme of amnion" EXACT [EMAPA:16265] xref: EMAPA:16265 ! mesenchyme of amnion xref: EHDAA:140 ! mesoderm xref: VHOG:0000622 ! amnion mesoderm xref: EHDAA2:0000118 ! amnion mesenchyme xref: EMAPA:16111 ! mesoderm of amnion is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000305 ! amnion relationship: develops_from UBERON:0005728 {source="EHDAA2"} ! extraembryonic mesoderm relationship: part_of UBERON:0000305 ! amnion [Term] id: UBERON:0005971 name: amniotic fold def: "A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]." [ISBN10:0073040584] xref: EMAPA:16076 ! amniotic fold is_a: UBERON:0000478 ! extraembryonic structure relationship: develops_from UBERON:0004874 {source="Kardong"} ! somatopleure [Term] id: UBERON:0003374 ! chorionic ectoderm name: chorionic ectoderm synonym: "chorion ectoderm" EXACT [OBOL:automatic] synonym: "chorionic epithelium" RELATED [BTO:0005145] synonym: "chorion epithelium" RELATED [] xref: EMAPA:16113 ! ectoderm of chorion xref: BTO:0005145 ! chorionic epithelium intersection_of: UBERON:0000478 ! extraembryonic structure intersection_of: part_of UBERON:0003124 ! chorion intersection_of: develops_from UBERON:0000924 ! ectoderm relationship: develops_from UBERON:0000924 {source="ISBN10:0073040584"} ! ectoderm [Term] id: UBERON:0003265 ! chorionic mesoderm alt_id: UBERON:0003423 name: chorionic mesoderm comment: TODO - check synonym: "chorion mesoderm" EXACT [RETIRED_EHDAA2:0000247] synonym: "chorionic mesenchyme" EXACT [EHDAA2:0003245] synonym: "chorion mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of chorion (vertebrates)" EXACT [OBOL:automatic] synonym: "chorionic mesenchyme" EXACT [EHDAA2:0003245] synonym: "mesenchyme of chorion" EXACT [] xref: EHDAA:154 ! mesoderm xref: VHOG:0000620 ! chorion mesoderm xref: RETIRED_EHDAA2:0000247 ! chorion mesoderm xref: EMAPA:16114 ! mesoderm of chorion xref: EMAPA:16266 ! mesenchyme of chorion xref: EHDAA2:0003245 ! chorionic mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure intersection_of: UBERON:0000478 ! extraembryonic structure intersection_of: part_of UBERON:0003124 ! chorion intersection_of: develops_from UBERON:0000926 ! mesoderm relationship: develops_from UBERON:0004871 {source="ISBN10:0073040584"} ! somatic layer of lateral plate mesoderm relationship: develops_from UBERON:0005728 {source="EHDAA2"} ! extraembryonic mesoderm [Term] id: UBERON:0004027 ! chorionic plate name: chorionic plate def: "hat portion of the chorionic wall in the region of its uterine attachment, which gives rise to chorionic villi; it consists of the mesoderm that lines the chorionic vesicle and, on the maternal side, of the trophoblast that lines the intervillous spaces; in the last half of gestation, the mesodermal connective tissue is largely replaced by fibrinoid material, and the amnionic membrane is adherent to the fetal side of the plate." [MP:0004560, http://www.medilexicon.com/medicaldictionary.php?t=69523] xref: BTO:0002879 ! chorionic plate xref: ncithesaurus:Chorionic_Plate ! Chorionic Plate is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0003124 ! chorion xref: SCTID:256391000 ! Entire chorionic plate xref: UMLS:C0230972 [Term] id: UBERON:0007106 name: chorionic villus def: "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta." [BTO:0001161, Wikipedia:Chorionic_villi] comment: Taxon notes: The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively. Histology notes: The bulk of the villi consist of connective tissues in which blood vessels are found. Most of the cells in the connective tissue core of the villi are fibroblasts. Macrophages known as Hofbauer cells are also present. synonym: "chorionic villus" RELATED [GAID:1300] synonym: "placental villi" RELATED [GAID:1300] synonym: "placental villus" RELATED [GAID:1300] synonym: "chorionic villi" RELATED [MESH:A16.254.403.473.200] synonym: "chorionic villous" RELATED [Wikipedia:Chorionic_villi] xref: BTO:0001161 ! chorionic villus xref: MESH:A16.254.403.473.200 is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0003124 {source="BTO"} ! chorion relationship: develops_from UBERON:0004027 {source="MP-def"} ! chorionic plate xref: ncithesaurus:Chorionic_Villus ! Chorionic Villus xref: EHDAA2:0004717 ! chorionic villus xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Gray29.png xref: SCTID:360403003 ! Entire placental villus xref: UMLS:C0008508 [Term] id: UBERON:0009993 name: primary chorionic villus def: "A chorionic villus that is a solid outgrowth of the cytotrophoblast that protrudes into the syncytiotrophoblast." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm] is_a: UBERON:0007106 {source="ncithesaurus"} ! chorionic villus xref: ncithesaurus:Primary_Chorionic_Villus ! Primary Chorionic Villus xref: UMLS:C1514421 [Term] id: UBERON:0009994 name: secondary chorionic villus def: "A chorionic villus that is has a core of loose connective tissue, which in humans grows into the primary villi about the third week of development." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm] is_a: UBERON:0007106 {source="ncithesaurus"} ! chorionic villus xref: ncithesaurus:Secondary_Chorionic_Villus ! Secondary Chorionic Villus xref: UMLS:C1519213 [Term] id: UBERON:0009995 name: tertiary chorionic villus def: "Tertiary chorionic villi contain embryonic blood vessels that develop from mesenchymal cells in the loose connective tissue core. These blood vessels connect up with vessels that develop in the chorion and connecting stalk and begin to circulate embryonic blood about the third week of development in humans." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm] is_a: UBERON:0007106 {source="ncithesaurus"} ! chorionic villus xref: ncithesaurus:Tertiary_Chorionic_Villus ! Tertiary Chorionic Villus xref: UMLS:C1515280 [Term] id: UBERON:0007108 name: vernix caseosa def: "An unctuous substance composed of sebum and desquamated epithelial cells, which covers the skin of the fetus." [MESH:A12.200.946, Wikipedia:Vernix_caseosa] synonym: "vernix caseosa" RELATED [MESH:A12.200.946] synonym: "vernix" RELATED [] xref: MESH:A12.200.946 ! vernix caseosa xref: GAID:1174 ! vernix caseosa is_a: UBERON:0000456 ! bodily secretion relationship: part_of UBERON:0000323 ! fetus relationship: surrounds UBERON:0002097 ! skin of body relationship: has_part UBERON:0001866 ! sebum xref: ncithesaurus:Vernix_Caseosa ! Vernix Caseosa xref: UMLS:C0042541 [Term] id: UBERON:0007109 name: meconium def: "A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth." [BTO:0000838] xref: BTO:0000838 ! meconium is_a: UBERON:0001988 ! feces relationship: part_of UBERON:0000323 ! fetus xref: ncithesaurus:Meconium ! Meconium [Term] id: UBERON:0003125 name: vitelline membrane def: "a structure directly adjacent to the outer surface of the plasma membrane of an ovum. It is composed mostly of protein fibers, with protein receptors needed for sperm binding, binding to sperm plasma membrane receptors. The species-specificity between these receptors contributes to prevention of breeding between different species [Wikipedia]. A protective layer around the egg[FBbt]." [Wikipedia:Vitelline_membrane] comment: TODO - consider GO CC request. GO:0030704-vitelline membrane formation considered a subclass of CC organization subset: dubious_grouping synonym: "zona pellucida" RELATED [] synonym: "yolk sac membrane" RELATED [BTO:0001450] xref: FBbt:00000042 ! vitelline membrane xref: GAID:1318 ! vitelline membrane xref: BTO:0001450 ! vitelline membrane xref: XAO:0000030 ! vitelline membrane xref: MESH:A16.631.886 ! vitelline membrane is_a: UBERON:0000061 ! anatomical structure relationship: surrounds CL:0000025 ! egg xref: AAO:0010332 ! vitelline membrane xref: VHOG:0000720 ! zona pellucida - vitelline membrane (also: UBERON:0000086 'zona pellucida') synonym: "m. vitellina" RELATED LATIN [Wikipedia:Vitelline_membrane] property_value: external_definition "Thin membrane enclosing and immediately adjacent to the ovum. Produced in the ovary.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010332", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of zygote (AAO:0010324)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010332", date_retrieved="2012-06-20"} synonym: "zona pellucida - vitelline membrane" BROAD [VHOG:0000720] property_value: homology_notes "Outside the plasma membrane, three envelopes surround the ovum. The first, the primary egg envelope, lies between the plasma membrane and the surrounding cells of the ovary. The most consistent component of this primary layer is the vitelline membrane, a transparent jacket of fibrous protein. In mammals, the homologous structure is called the zona pellucida.[well established][VHOG]" xsd:string {external_class="VHOG:0000720", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.159", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003130 name: arthropod sternum def: "ventral portion of a segment of an arthropod thorax or abdomen. In insects, the sterna are usually single, large sclerites, and external. However, they can sometimes be divided in two or more, in which case the subunits are called sternites, and may also be modified on the terminal abdominal segments so as to form part of the functional genitalia, in which case they are frequently reduced in size and development, and may become internalized and/or membranous." [Wikipedia:Sternum_(arthropod)] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology synonym: "sternum" BROAD [] xref: FBbt:00004557 ! sternum xref: HAO:0000956 ! sternum is_a: UBERON:0000061 ! anatomical structure relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0003131 name: arthropod tibia def: "A section of the arthropod leg." [Wikipedia:Arthropod_leg] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology. Homology notes: homology of leg segments between groups are difficult to prove and are the source of much argument. Some authors posit up to eleven segments per leg for the most recent common ancestor of extant arthropods [1], but modern arthropods have eight or fewer. It has been argued [2][3] that the ancestral leg need not have been so complex, and that other events, such as the successive loss of function of a Hox-gene could result in parallel gains of leg segments. xref: FBbt:00004642 ! tibia xref: HAO:0001017 ! tibia xref: TADS:0000281 ! adult tibia is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0005895 ! insect leg relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0003132 name: arthropod hypopharynx def: "A median tonguelike structure arising from the mouth." [http://www.britannica.com/EBchecked/topic/279974/hypopharynx] comment: Editor notes: this term should be ceded to the arthropod anatomy ontology xref: FBbt:00005751 ! hypopharynx xref: HAO:0000409 ! hypopharynx xref: TGMA:0000090 ! adult hypopharynx is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0006562 ! pharynx relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0003133 ! reproductive organ name: reproductive organ def: "An organ involved in reproduction" [UBERON:xp] comment: GO uses genitalia for the singular organ subset: functional_classification synonym: "reproductive system organ" EXACT [] synonym: "sex organ" EXACT [] synonym: "genital organ" EXACT [] synonym: "genitalia" RELATED PLURAL [] xref: MA:0001752 ! reproductive organ xref: OpenCyc:Mx4rwO39aJwpEbGdrcN5Y29ycA ! reproductive organ xref: TGMA:0000591 ! genitalia xref: EMAPA:17381 ! reproductive system (also: UBERON:0000990 'reproductive system') xref: MESH:A05.360 ! genitalia xref: WBbt:0008422 ! sex organ is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0000003 relationship: part_of UBERON:0000990 ! reproductive system xref: ncithesaurus:Genitalia ! Genitalia xref: SCTID:128181006 ! Entire genital organ subset: organ_slim xref: UMLS:C0017420 [Term] id: UBERON:0003136 name: obsolete tagma comment: arthropod specific groupings belong in separate ontology consider: FBbt:00000002 ! tagma consider: HAO:0000988 ! tagma is_obsolete: true [Term] id: UBERON:0003137 name: obsolete antennal segment comment: arthropod specific groupings belong in separate ontology consider: FBbt:00000009 ! antennal segment consider: HAO:0000104 ! antennal segment is_obsolete: true [Term] id: UBERON:0003138 name: obsolete thoracic segment comment: arthropod specific groupings belong in separate ontology consider: FBbt:00000016 ! thoracic segment consider: HAO:0001013 ! thoracic segment is_obsolete: true [Term] id: UBERON:0003139 name: obsolete larval tagma comment: arthropod specific groupings belong in separate ontology consider: FBbt:00001728 ! larval tagma consider: HAO:0000462 ! larval tagma is_obsolete: true [Term] id: UBERON:0003140 name: obsolete larval thorax comment: arthropod specific groupings belong in separate ontology consider: FBbt:00001741 ! larval thorax consider: HAO:0000463 ! larval thorax is_obsolete: true [Term] id: UBERON:0003141 name: obsolete larval abdomen consider: FBbt:00001746 ! larval abdomen consider: HAO:0000460 ! larval abdomen is_obsolete: true [Term] id: UBERON:0003142 name: prepupa synonym: "PP" RELATED [FBbt:00002952] xref: FBbt:00002952 ! prepupa xref: HAO:0000812 ! prepupa xref: BTO:0001110 ! prepupa is_a: UBERON:0000468 ! multi-cellular organism relationship: develops_from UBERON:0002548 ! larva [Term] id: UBERON:0003143 name: pupa def: "Organism at the pupal stage. The pupal stage is a life stage of some insects undergoing transformation. The pupal stage is found only in holometabolous insects, those that undergo a complete metamorphosis, going through four life stages; embryo, larva, pupa and imago." [Wikipedia:Pupa] synonym: "aurelia" NARROW [Wikipedia:Pupa, NCBITaxon:37572] synonym: "chrysalis" NARROW [Wikipedia:Pupa, NCBITaxon:37572] synonym: "chrysalides" NARROW PLURAL [Wikipedia:Pupa, NCBITaxon:37572] synonym: "pupae" RELATED PLURAL [] xref: FBbt:00002953 ! pupa xref: HAO:0000886 ! pupa xref: BTO:0001143 ! pupa xref: EFO:0002684 ! pupa xref: OpenCyc:Mx4rwQCBr5wpEbGdrcN5Y29ycA ! pupa intersection_of: UBERON:0000468 ! multi-cellular organism intersection_of: existence_starts_and_ends_during UBERON:0000070 ! pupal stage relationship: only_in_taxon NCBITaxon:33392 ! Endopterygota property_value: has_relational_adjective "pupal" xsd:string [Term] id: UBERON:0013198 name: cocoon def: "A casing spun of silk by many moth caterpillars, and numerous other holometabolous insect larvae as a protective covering for the pupa[WP]." [http://en.wikipedia.org/wiki/Pupa#Cocoon] comment: analagous to a puparium in other insects is_a: UBERON:0000463 ! portion of organism substance relationship: composed_primarily_of UBERON:0012245 ! silk relationship: surrounds UBERON:0003143 ! pupa relationship: never_in_taxon NCBITaxon:37572 ! Papilionoidea relationship: only_in_taxon NCBITaxon:33392 ! Endopterygota [Term] id: UBERON:0003144 name: obsolete adult tagma comment: arthropod specific groupings belong in separate ontology consider: FBbt:00003005 ! adult tagma consider: HAO:0000089 ! adult tagma is_obsolete: true [Term] id: UBERON:0003145 name: obsolete adult arthropod thorax comment: arthropod specific groupings belong in separate ontology consider: FBbt:00003018 ! adult thorax consider: HAO:0000090 ! adult thorax is_obsolete: true [Term] id: UBERON:0003146 name: obsolete adult arthropod abdomen consider: FBbt:00003023 ! adult abdomen consider: HAO:0000088 ! adult abdomen is_obsolete: true [Term] id: UBERON:0003147 name: obsolete peritreme def: "That part of the integument of an insect which surrounds the spiracles." [http://www.answers.com/topic/peritreme] comment: arthropod specific groupings belong in separate ontology. term also used for edge of the aperture of a univalve shell synonym: "rim" RELATED [FBbt:00003121] consider: FBbt:00003121 ! peritreme consider: HAO:0000712 ! peritreme is_obsolete: true [Term] id: UBERON:0003148 ! sclerite name: obsolete sclerite def: "hardened portions of arthropod exoskeletons." [Wikipedia:Sclerite] comment: arthropod specific groupings belong in separate ontology synonym: "plate" RELATED [FBbt:00004475] consider: FBbt:00004475 ! sclerite consider: HAO:0000909 ! sclerite is_obsolete: true [Term] id: UBERON:0003192 name: obsolete axillary sclerite comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004737 ! axillary sclerite consider: HAO:0000159 ! axillary sclerite is_obsolete: true [Term] id: UBERON:0003149 name: obsolete tergite comment: arthropod specific groupings belong in separate ontology synonym: "abdominal tergite" EXACT [FBbt:00004476] consider: FBbt:00004476 ! tergite consider: HAO:0001005 ! tergite is_obsolete: true [Term] id: UBERON:0003150 name: obsolete sternite comment: arthropod specific groupings belong in separate ontology synonym: "abdominal sternite" EXACT [FBbt:00004477] consider: FBbt:00004477 ! sternite consider: HAO:0000955 ! sternite is_obsolete: true [Term] id: UBERON:0003151 name: obsolete foramen comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004478 ! foramen consider: HAO:0000345 ! foramen is_obsolete: true [Term] id: UBERON:0003152 name: obsolete phragma def: "The lamella that serves as the site of attachment of the longitudinal flight muscle [HAO]." [HAO:0000716] comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004480 ! phragma consider: HAO:0000716 ! phragma is_obsolete: true [Term] id: UBERON:0003153 name: head capsule xref: FBbt:00004482 ! head capsule xref: HAO:0000398 ! head capsule xref: EFO:0001927 ! head capsule xref: BTO:0004711 ! head capsule is_a: UBERON:0000477 ! anatomical cluster [Term] id: UBERON:0003154 name: obsolete gena comment: arthropod specific groupings belong in separate ontology synonym: "cheek" RELATED [FBbt:00004491] consider: FBbt:00004491 ! gena consider: HAO:0000371 ! gena is_obsolete: true [Term] id: UBERON:0003155 name: arthropod occiput comment: arthropod specific groupings belong in separate ontology, but this is retained for disambiguation purposes synonym: "occiput" RELATED SENSU [FBbt:00004492] xref: FBbt:00004492 ! occiput xref: HAO:0000658 ! occiput xref: TGMA:0000041 ! occiput is_a: UBERON:0006056 ! posterior region of head disjoint_from: UBERON:0006054 ! surface of occiput relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0006054 ! surface of occiput name: surface of occiput def: "The occiput is the anatomical term for the posterior (back) portion of the head." [Wikipedia:Occiput] synonym: "occiput" RELATED [FMA:46479] synonym: "occiput surface" EXACT [FMA:46479] synonym: "regio occipitalis (capitis)" EXACT [FMA:46479] xref: FMA:46479 ! surface of occiput is_a: UBERON:0006056 ! posterior region of head xref: galen:Occiput synonym: "occiput cranii" RELATED LATIN [Wikipedia:Occiput] xref: http://upload.wikimedia.org/wikipedia/commons/e/eb/Double_cowlick.jpg [Term] id: UBERON:0006056 ! posterior surface of head name: posterior surface of head is_a: UBERON:0000015 ! anatomical boundary relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0003156 name: obsolete postocciput comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004494 ! postocciput consider: HAO:0000790 ! postocciput is_obsolete: true [Term] id: UBERON:0003157 name: obsolete postgena comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004496 ! postgena consider: HAO:0000776 ! postgena is_obsolete: true [Term] id: UBERON:0003158 name: obsolete tentorial pit comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004501 ! tentorial pit consider: HAO:0000999 ! tentorial pit is_obsolete: true [Term] id: UBERON:0003159 name: obsolete anterior tentorial pit comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004502 ! anterior tentorial pit consider: HAO:0000126 ! anterior tentorial pit is_obsolete: true [Term] id: UBERON:0003160 name: obsolete posterior tentorial pit comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004503 ! posterior tentorial pit consider: HAO:0000768 ! posterior tentorial pit is_obsolete: true [Term] id: UBERON:0003161 name: dorsal ocellus def: "A simple visual organ of insects[GO]. Two ocelli appear on the vertical and one on the frontal plate[FBbt]. The multi-tissue structure that is located on the top of the head, composed of the corneal lens, pigment cell, rhabdoms and synaptic plexus[HAO]. Two evolutionary distinct ocellus types exist [2]: dorsal ocelli (or simply 'ocelli'), found in most insects, and lateral ocelli (or stemmata), which are found in the larvae of some insect orders. They are structurally and functionally very different. Simple eyes of other animals, e.g. cnidarians may also be referred to as 'ocelli', but again the structure and anatomy of these eyes is quite distinct from those of the dorsal ocelli of insects[Wikipedia]." [FBbt:00004505, GO:0008056, HAO:0000661, Wikipedia:Ocellus#Ocelli] synonym: "dorsal ocelli" RELATED PLURAL [] synonym: "ocelli" RELATED PLURAL [] synonym: "ocellus" EXACT [] xref: FBbt:00004505 ! ocellus xref: HAO:0000661 ! ocellus xref: BTO:0001758 ! ocellus is_a: UBERON:0000963 ! head sensillum [Term] id: UBERON:0003162 name: lateral ocellus def: "The ocellus that is paired[HAO]. The number, form, and function of the dorsal ocelli varies markedly throughout insect orders. They tend to be larger and more strongly expressed in flying insects (particularly bees, wasps, dragonflies and locusts), where they are typically found as a triplet. Two lateral ocelli are directed to the left and right of the head respectively, while a central (median) ocellus is directed frontally. In some terrestrial insects (e.g. some ants and cockroaches), only two lateral ocelli are present: the median ocellus is absent. Note that the unfortunately labelled 'lateral ocelli' here refers to the sideways facing position of the ocelli, which are of the dorsal type. They should not be confused with the lateral ocelli of some insect larvae (see stemmata)[Wikipedia]." [HAO:0000481, Wikipedia:Ocellus#Ocelli] xref: FBbt:00004506 ! lateral ocellus xref: HAO:0000481 ! lateral ocellus is_a: UBERON:0003161 ! dorsal ocellus [Term] id: UBERON:0003163 name: obsolete mouthpart comment: TODO consider: FBbt:00004520 ! mouthpart consider: HAO:0000639 ! mouthparts is_obsolete: true [Term] id: UBERON:0003164 name: obsolete clypeus comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004521 ! clypeus consider: HAO:0000212 ! clypeus is_obsolete: true [Term] id: UBERON:0003165 name: obsolete cibarium comment: arthropod specific groupings belong in separate ontology synonym: "atrium" RELATED [FBbt:00004526] consider: FBbt:00004526 ! cibarium consider: HAO:0000201 ! cibarium is_obsolete: true [Term] id: UBERON:0003166 name: obsolete prementum comment: arthropod specific groupings belong in separate ontology synonym: "theca" RELATED [FBbt:00004534] consider: FBbt:00004534 ! prementum consider: HAO:0000804 ! prementum is_obsolete: true [Term] id: UBERON:0003167 name: obsolete lacinia comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004536 ! lacinia consider: HAO:0000457 ! lacinia is_obsolete: true [Term] id: UBERON:0003168 name: obsolete mentum comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004544 ! mentum consider: HAO:0000534 ! mentum is_obsolete: true [Term] id: UBERON:0003169 name: obsolete cervical sclerite comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004548 ! cervical sclerite consider: HAO:0000195 ! cervical sclerite is_obsolete: true [Term] id: UBERON:0003170 name: obsolete tergum comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004552 ! tergum consider: HAO:0001006 ! tergum is_obsolete: true [Term] id: UBERON:0003171 name: obsolete episternum comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004554 ! episternum consider: HAO:0000303 ! episternum is_obsolete: true [Term] id: UBERON:0003172 name: obsolete epimeron comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004556 ! epimeron consider: HAO:0000299 ! epimeron is_obsolete: true [Term] id: UBERON:0003173 name: obsolete pronotum comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004561 ! pronotum consider: HAO:0000853 ! pronotum is_obsolete: true [Term] id: UBERON:0003174 name: obsolete furcasternum comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004570 ! furcasternum consider: HAO:0000367 ! furcasternum is_obsolete: true [Term] id: UBERON:0003175 name: obsolete prescutum comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004582 ! prescutum consider: HAO:0000815 ! prescutum is_obsolete: true [Term] id: UBERON:0003176 name: obsolete anterior notal wing process comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004585 ! anterior notal wing process consider: HAO:0000120 ! anterior notal wing process is_obsolete: true [Term] id: UBERON:0003177 name: obsolete posterior notal wing process comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004586 ! posterior notal wing process consider: HAO:0000758 ! posterior notal wing process is_obsolete: true [Term] id: UBERON:0003178 name: obsolete postnotum comment: arthropod specific groupings belong in separate ontology synonym: "postscutellum" RELATED [FBbt:00004588] consider: FBbt:00004588 ! postnotum consider: HAO:0000786 ! postnotum is_obsolete: true [Term] id: UBERON:0003179 name: obsolete pleural wing process comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004595 ! pleural wing process consider: HAO:0000726 ! pleural wing process is_obsolete: true [Term] id: UBERON:0003180 name: obsolete anepisternum comment: arthropod specific groupings belong in separate ontology synonym: "mesopleurite" RELATED [FBbt:00004597] consider: FBbt:00004597 ! anepisternum consider: HAO:0000094 ! anepisternum is_obsolete: true [Term] id: UBERON:0003181 name: obsolete scutoscutellar suture comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004601 ! scutoscutellar suture consider: HAO:0000920 ! scutoscutellar suture is_obsolete: true [Term] id: UBERON:0003182 name: obsolete pleural suture consider: FBbt:00004603 ! pleural suture consider: HAO:0000725 ! pleural suture is_obsolete: true [Term] id: UBERON:0003183 name: obsolete notopleural suture consider: FBbt:00004604 ! notopleural suture consider: HAO:0000649 ! notopleural suture is_obsolete: true [Term] id: UBERON:0003184 name: obsolete mesofurca comment: arthropod specific groupings belong in separate ontology synonym: "mesothoracic sternal apophysis" RELATED [FBbt:00004619] consider: FBbt:00004619 ! mesofurca consider: HAO:0000547 ! mesofurca is_obsolete: true [Term] id: UBERON:0003185 name: obsolete metafurca comment: arthropod specific groupings belong in separate ontology synonym: "metathoracic sternal apophysis" RELATED [FBbt:00004638] consider: FBbt:00004638 ! metafurca consider: HAO:0000592 ! metafurca is_obsolete: true [Term] id: UBERON:0003186 name: obsolete coxa comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004641 ! coxa consider: HAO:0000228 ! coxa is_obsolete: true [Term] id: UBERON:0003187 name: obsolete pretarsus comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004653 ! pretarsus consider: HAO:0000820 ! pretarsus is_obsolete: true [Term] id: UBERON:0003188 name: obsolete auxilia comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004654 ! auxilia consider: HAO:0000153 ! auxilia is_obsolete: true [Term] id: UBERON:0003189 name: obsolete unguitractor plate comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004658 ! unguitractor plate consider: HAO:0001043 ! unguitractor plate is_obsolete: true [Term] id: UBERON:0003190 name: obsolete empodium consider: FBbt:00004659 ! empodium consider: HAO:0000288 ! empodium is_obsolete: true [Term] id: UBERON:0003191 name: obsolete tegula comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004730 ! tegula consider: HAO:0000993 ! tegula is_obsolete: true [Term] id: UBERON:0003193 name: obsolete axillary cord comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004744 ! axillary cord consider: HAO:0000157 ! axillary cord is_obsolete: true [Term] id: UBERON:0003194 name: imaginal disc-derived wing vein xref: FBbt:00004751 ! wing vein xref: HAO:0001095 ! wing vein is_a: UBERON:0000476 ! acellular anatomical structure relationship: part_of UBERON:0000984 ! imaginal disc-derived wing [Term] id: UBERON:0003195 name: obsolete crossvein comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004765 ! crossvein consider: HAO:0000236 ! crossvein is_obsolete: true [Term] id: UBERON:0003196 name: obsolete wing cell comment: arthropod specific groupings belong in separate ontology synonym: "intervein" RELATED [FBbt:00004769] consider: FBbt:00004769 ! wing cell consider: HAO:0001091 ! wing cell is_obsolete: true [Term] id: UBERON:0003197 name: obsolete costal cell comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004770 ! costal cell consider: HAO:0000226 ! costal cell is_obsolete: true [Term] id: UBERON:0003198 name: obsolete aedeagus comment: arthropod specific groupings belong in separate ontology consider: FBbt:00004850 ! aedeagus consider: HAO:0000091 ! aedeagus is_obsolete: true [Term] id: UBERON:0003199 name: egg chamber synonym: "follicle" RELATED [FBbt:00004894] synonym: "germarium derived egg chamber" EXACT [FBbt:00004894] xref: FBbt:00004894 ! egg chamber xref: HAO:0000287 ! egg chamber is_a: UBERON:0000464 ! anatomical space xref: ncithesaurus:Follicle ! Follicle xref: UMLS:C1571705 [Term] id: UBERON:0003200 name: obsolete pedicel consider: FBbt:00004920 ! pedicel consider: HAO:0000706 ! pedicel is_obsolete: true [Term] id: UBERON:0003201 name: exocuticle def: "The outer layer of the procuticle of certain crustaceans and arthropods, which contains cuticulin, chitin, and phenolic substances that are oxidized to produce the dark pigment of the cuticle;nThe hard and usually darkened layer of the cuticle lying between the endocuticle and epicuticle." [BTO:0001602] xref: FBbt:00004973 ! exocuticle xref: HAO:0000311 ! exocuticle xref: BTO:0001602 ! exocuticle is_a: UBERON:0000476 ! acellular anatomical structure [Term] id: UBERON:0003202 name: endocuticle def: "The inner layer of the procuticle in certain crustaceans and arthropods, which is almost entirely composed of protein and chitin." [BTO:0001603] xref: FBbt:00004974 ! endocuticle xref: HAO:0000290 ! endocuticle xref: BTO:0001603 ! endocuticle is_a: UBERON:0000476 ! acellular anatomical structure [Term] id: UBERON:0003203 name: obsolete apodeme comment: arthropod specific groupings belong in separate ontology consider: FBbt:00005091 ! apodeme consider: HAO:0000142 ! apodeme is_obsolete: true [Term] id: UBERON:0003204 name: obsolete epipharynx comment: arthropod specific groupings belong in separate ontology consider: FBbt:00005750 ! epipharynx consider: HAO:0000301 ! epipharynx is_obsolete: true [Term] id: UBERON:0003205 name: obsolete articulation comment: incorrect grouping consider: FBbt:00005811 ! articulation consider: HAO:0000151 ! articulation consider: ncithesaurus:Articulation ! Articulation is_obsolete: true [Term] id: UBERON:0003206 name: obsolete apophysis comment: incorrect grouping consider: FBbt:00005813 ! apophysis consider: HAO:0000143 ! apophysis consider: FMA:75428 ! Apophysis is_obsolete: true [Term] id: UBERON:0003207 name: obsolete arthropod appendage segment comment: arthropod specific groupings belong in separate ontology consider: HAO:0000145 ! appendage segment is_obsolete: true [Term] id: UBERON:0003209 name: blood nerve barrier def: "barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier[GO]." [GO:0008065, Wikipedia:Blood-nerve_barrier] synonym: "blood-nerve barrier" EXACT [] is_a: UBERON:0000119 ! cell layer relationship: adjacent_to UBERON:0000179 ! haemolymphatic fluid relationship: adjacent_to UBERON:0001021 ! nerve [Term] id: UBERON:0003210 name: blood-cerebrospinal fluid barrier def: "barrier in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood[MP]." [MP:0006088] is_a: UBERON:0000119 ! cell layer relationship: adjacent_to UBERON:0000178 ! blood relationship: adjacent_to UBERON:0001359 ! cerebrospinal fluid [Term] id: UBERON:0003211 name: median ocellus def: "The ocellus that is is located medially on the cranium[HAO]. The number, form, and function of the dorsal ocelli varies markedly throughout insect orders. They tend to be larger and more strongly expressed in flying insects (particularly bees, wasps, dragonflies and locusts), where they are typically found as a triplet. Two lateral ocelli are directed to the left and right of the head respectively, while a central (median) ocellus is directed frontally. In some terrestrial insects (e.g. some ants and cockroaches), only two lateral ocelli are present: the median ocellus is absent. Note that the unfortunately labelled 'lateral ocelli' here refers to the sideways facing position of the ocelli, which are of the dorsal type. They should not be confused with the lateral ocelli of some insect larvae (see stemmata)[Wikipedia]." [HAO:0000526, Wikipedia:Ocellus#Ocelli] xref: FBbt:00004507 ! medial ocellus xref: HAO:0000526 ! median ocellus is_a: UBERON:0003161 ! dorsal ocellus [Term] id: UBERON:0003212 name: gustatory organ def: "Any sense organ that functions in (some) detection of chemical stimulus involved in sensory perception of taste (GO:0050912)." [FBC:auto_generated_definition] synonym: "taste organ" EXACT [] synonym: "gustatory organ system organ" EXACT [OBOL:automatic] synonym: "gustatory system organ" EXACT [OBOL:automatic] synonym: "organ of gustatory organ system" EXACT [OBOL:automatic] synonym: "organ of gustatory system" EXACT [OBOL:automatic] synonym: "organ of taste system" EXACT [OBOL:automatic] synonym: "taste system organ" EXACT [OBOL:automatic] xref: FBbt:00005159 ! gustatory sensory organ xref: FMA:77853 ! Gustatory organ is_a: UBERON:0000005 ! chemosensory sensory organ intersection_of: UBERON:0000062 ! organ intersection_of: has_function_in GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste relationship: part_of UBERON:0001033 ! gustatory system [Term] id: UBERON:0003214 name: mammary gland alveolus def: "a sac-like structure that is found in the mature gland[GO]." [GO:0060749] synonym: "lactiferous alveolus" EXACT [] synonym: "lactiferous gland alveolus" EXACT [] synonym: "mammary alveolus" EXACT [] synonym: "alveolus of lactiferous gland" EXACT [OBOL:automatic] synonym: "alveolus of lobe of breast" EXACT [OBOL:automatic] synonym: "alveolus of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "alveolus of mammary gland" EXACT [OBOL:automatic] synonym: "lobe of breast alveolus" EXACT [OBOL:automatic] synonym: "lobe of mammary gland alveolus" EXACT [OBOL:automatic] xref: FMA:73285 ! Alveolus of lactiferous gland xref: MA:0002760 ! mammary gland alveolus is_a: UBERON:0003215 ! alveolus intersection_of: UBERON:0003215 ! alveolus intersection_of: part_of UBERON:0001911 ! lactiferous gland relationship: part_of UBERON:0001911 ! lactiferous gland relationship: part_of UBERON:0001912 ! lobule of lactiferous gland [Term] id: UBERON:0003215 name: alveolus def: "organ part that has the form of a hollow cavity[WP]." [Wikipedia:Alveolus] xref: FMA:82493 ! Alveolus xref: ncithesaurus:Alveolus ! Alveolus xref: EFO:0002513 ! alveolus xref: OpenCyc:Mx4rwN8NFZwpEbGdrcN5Y29ycA ! alveolus xref: EV:0100043 ! alveolus (also: UBERON:0002299 'alveolus of lung') is_a: UBERON:0000064 ! organ part property_value: has_relational_adjective "alveolar" xsd:string xref: UMLS:C0034051 [Term] id: UBERON:0003218 name: ovary septum def: "Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]." [GO:0080126] intersection_of: UBERON:0003037 ! septum intersection_of: part_of UBERON:0000992 [Term] id: UBERON:0003219 name: shell septum def: "Septum that divides the internal chambers (camerae) of the shell of a cephalopod, namely nautiloids or ammonoids." [GO:0080126, Wikipedia:Septum_(marine_biology)] intersection_of: UBERON:0003037 ! septum intersection_of: part_of UBERON:0006612 ! shell [Term] id: UBERON:0006611 ! exoskeleton name: exoskeleton def: "Exoskeleton or shell, including those of mollusks, turtles, insects and crustaceans." [Wikipedia:Exoskeleton] comment: Usage notes: not to be confused with dermal skeleton synonym: "shell" RELATED [BTO:0004659] synonym: "test" NARROW [] synonym: "lorica" NARROW [Wikipedia:Lorica_(biology)] xref: BTO:0004659 ! exoskeleton is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0002416 ! integumental system subset: grouping_class property_value: has_relational_adjective "exoskeletal" xsd:string [Term] id: UBERON:0006612 name: shell def: "A rigid covering that envelops an object." [Wikipedia:Seashell, ncithesaurus:Shell] comment: Editor notes: may be obsoleted after integumental system overhaul is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0002416 ! integumental system xref: ncithesaurus:Shell ! Shell subset: grouping_class [Term] id: UBERON:0001002 name: cuticle def: "tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]." [Wikipedia:Cuticle, http://sourceforge.net/tracker/?func=detail&aid=3348965&group_id=36855&atid=440764] comment: TODO - check cuticle vs exoskeleton. Note that GO has a very generic definition of cuticle. See also arthropod-anatomy ontology. Note in ncit Cuticle is a plant part subset: uberon_slim synonym: "cuticula" RELATED [BTO:0001600] xref: BTO:0001600 ! cuticle is_a: UBERON:0000476 ! acellular anatomical structure disjoint_from: UBERON:0004882 ! eponychium property_value: has_relational_adjective "cuticular" xsd:string [Term] id: UBERON:0001001 name: chitin-based cuticle alt_id: UBERON:FBbt_00004970 def: "The main structural component of arthropod cuticle is a polysaccharide, chitin, composed of N-acetylglucosamine units, together with proteins and lipids[WP]." [UBERON:cjm, Wikipedia:Cuticle#Invertebrate_zoology, https://sourceforge.net/tracker/index.php?func=detail&aid=3348965&group_id=36855&atid=440764] comment: TODO - split from exoskeleton? Also: See above sf item to see if this belongs in GO subset: uberon_slim synonym: "arthropod cuticle" RELATED [] synonym: "exoskeleton" BROAD [] synonym: "insect cuticle" RELATED [] synonym: "cuticle" NARROW [FBbt:00004970] xref: HAO:0000240 ! cuticle xref: FBbt:00004970 ! cuticle xref: EFO:0000944 ! exoskeleton xref: MAT:0000150 ! exoskeleton xref: MIAA:0000150 ! exoskeleton xref: OpenCyc:Mx4rvVkBTJwpEbGdrcN5Y29ycA ! exoskeleton intersection_of: UBERON:0001002 ! cuticle intersection_of: composed_primarily_of CHEBI:17029 ! chitin relationship: develops_from UBERON:0007376 ! outer epithelial layer relationship: part_of UBERON:0002416 ! integumental system relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0003221 name: phalanx def: "Endochondral bones that are often elongate and arranged in rows of articulating elements, and form the visible part of the digits." [VSAO:0000199, Wikipedia:Phalanx_bones] comment: Taxon notes: In primates such as humans and monkeys, the thumb and big toe have two phalanges, while the other fingers and toes consist of three[WP] synonym: "phalanx bone" EXACT [Wikipedia:Phalanx_bones] synonym: "phalanges" EXACT PLURAL [] synonym: "phalange" EXACT [] synonym: "digit long bone" EXACT [OBOL:automatic] synonym: "long bone of digit" EXACT [OBOL:automatic] xref: MA:0000304 ! phalanx xref: ncithesaurus:Phalanx ! Phalanx xref: galen:Phalanx ! phalanx xref: OpenCyc:Mx4rvolPZpwpEbGdrcN5Y29ycA ! phalanx is_a: UBERON:0002495 ! long bone intersection_of: UBERON:0002495 ! long bone intersection_of: part_of UBERON:0002544 ! digit relationship: part_of UBERON:0010543 ! acropodial skeleton relationship: develops_from UBERON:0010701 ! phalanx cartilage condensation xref: SCTID:290029003 ! Entire phalanx xref: VSAO:0000199 ! phalanx property_value: has_relational_adjective "phalangeal" xsd:string xref: UMLS:C0222682 [Term] id: UBERON:0003224 name: chorion syncytiotrophoblast comment: todo - check xref: EHDAA:156 ! syncytiotrophoblast xref: EHDAA2:0001973 ! chorion syncytiotrophoblast intersection_of: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure intersection_of: part_of UBERON:0003124 ! chorion intersection_of: develops_from UBERON:0000371 {source="Obol"} ! syncytiotrophoblast def: "An extraembryonic structure that develops_from a syncytiotrophoblast and is part of a chorion." [OBOL:automatic] [Term] id: UBERON:0003229 name: epithelium of elbow def: "An epithelium that is part of a elbow [Automatically generated definition]." [OBOL:automatic] synonym: "cubital region epithelial tissue" EXACT [OBOL:automatic] synonym: "cubital region epithelium" EXACT [OBOL:automatic] synonym: "elbow epithelial tissue" EXACT [OBOL:automatic] synonym: "elbow epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of cubital region" EXACT [OBOL:automatic] synonym: "epithelial tissue of elbow" EXACT [OBOL:automatic] synonym: "epithelium of cubital region" EXACT [OBOL:automatic] xref: EHDAA:4168 ! epithelium xref: EHDAA:6214 ! epithelium xref: VHOG:0001044 ! elbow epithelium xref: EHDAA2:0000430 ! elbow epithelium xref: EMAPA:17415 ! epithelium of elbow intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001461 ! elbow relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm [Term] id: UBERON:0003230 name: epithelium of carpal region def: "An epithelium that is part of a wrist [Automatically generated definition]." [OBOL:automatic] synonym: "carpal region epithelial tissue" EXACT [OBOL:automatic] synonym: "carpal region epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of carpal region" EXACT [OBOL:automatic] synonym: "epithelial tissue of wrist" EXACT [OBOL:automatic] synonym: "epithelium of wrist" EXACT [OBOL:automatic] synonym: "wrist epithelial tissue" EXACT [OBOL:automatic] synonym: "wrist epithelium" EXACT [OBOL:automatic] xref: EHDAA:5198 ! epithelium xref: EHDAA2:0000219 ! carpal region epithelium is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0003231 name: epithelium of hip def: "An epithelium that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of hip" EXACT [OBOL:automatic] synonym: "epithelial tissue of hip region" EXACT [OBOL:automatic] synonym: "epithelial tissue of regio coxae" EXACT [OBOL:automatic] synonym: "epithelium of hip region" EXACT [OBOL:automatic] synonym: "epithelium of regio coxae" EXACT [OBOL:automatic] synonym: "hip epithelial tissue" EXACT [OBOL:automatic] synonym: "hip epithelium" EXACT [OBOL:automatic] synonym: "hip region epithelial tissue" EXACT [OBOL:automatic] synonym: "hip region epithelium" EXACT [OBOL:automatic] synonym: "regio coxae epithelial tissue" EXACT [OBOL:automatic] synonym: "regio coxae epithelium" EXACT [OBOL:automatic] xref: EHDAA:5155 ! epithelium xref: EHDAA:6180 ! epithelium xref: VHOG:0000779 ! hip epithelium xref: EHDAA2:0000784 ! hip epithelium xref: EMAPA:17491 ! epithelium of hip intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001464 ! hip relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm [Term] id: UBERON:0003232 name: epithelium of knee def: "An epithelium that is part of a knee [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of knee" EXACT [OBOL:automatic] synonym: "knee epithelial tissue" EXACT [OBOL:automatic] synonym: "knee epithelium" EXACT [OBOL:automatic] xref: EHDAA:5161 ! epithelium xref: EHDAA:6186 ! epithelium xref: VHOG:0000810 ! knee epithelium xref: EHDAA2:0000896 ! knee epithelium xref: EMAPA:17494 ! epithelium of knee intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001465 ! knee relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm [Term] id: UBERON:0003233 name: epithelium of shoulder def: "An epithelium that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of shoulder" EXACT [OBOL:automatic] synonym: "shoulder epithelial tissue" EXACT [OBOL:automatic] synonym: "shoulder epithelium" EXACT [OBOL:automatic] xref: EHDAA:4182 ! epithelium xref: EHDAA:6230 ! epithelium xref: VHOG:0000761 ! shoulder epithelium xref: EHDAA2:0001835 ! shoulder epithelium xref: EMAPA:17422 ! epithelium of shoulder intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001467 ! shoulder relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm [Term] id: UBERON:0003235 name: epithelium of upper jaw def: "An epithelium that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "epithelial tissue of upper jaw" EXACT [OBOL:automatic] synonym: "epithelium of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "palatoquadrate arch epithelial tissue" EXACT [OBOL:automatic] synonym: "palatoquadrate arch epithelium" EXACT [OBOL:automatic] synonym: "upper jaw epithelial tissue" EXACT [OBOL:automatic] synonym: "upper jaw epithelium" EXACT [OBOL:automatic] xref: EHDAA:8027 ! epithelium xref: EHDAA2:0002119 ! upper jaw epithelium xref: EMAPA:17943 ! epithelium of molar of tooth of upper jaw (also: UBERON:0005653 'upper jaw molar epithelium') xref: EMAPA:18971 ! epithelium of gum of upper jaw is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0003236 name: epithelium of lower jaw def: "An epithelium that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lower jaw" EXACT [OBOL:automatic] synonym: "epithelial tissue of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "epithelium of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "lower jaw epithelial tissue" EXACT [OBOL:automatic] synonym: "lower jaw epithelium" EXACT [OBOL:automatic] synonym: "ventral mandibular arch epithelial tissue" EXACT [OBOL:automatic] synonym: "ventral mandibular arch epithelium" EXACT [OBOL:automatic] xref: EHDAA:7999 ! epithelium xref: VHOG:0000802 ! lower jaw epithelium xref: EHDAA2:0001019 ! lower jaw epithelium xref: EMAPA:17922 ! epithelium of molar of tooth of lower jaw (also: UBERON:0005654 'lower jaw molar epithelium') xref: EMAPA:18968 ! epithelium of gum of lower jaw is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0003238 name: epithelium of superior semicircular canal def: "An epithelium that is part of an anterior semicircular canal [Automatically generated definition]." [OBOL:automatic] synonym: "anterior semicircular canal epithelial tissue" EXACT [OBOL:automatic] synonym: "anterior semicircular canal epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of anterior semicircular canal" EXACT [OBOL:automatic] synonym: "epithelial tissue of superior semicircular canal" EXACT [OBOL:automatic] synonym: "epithelium of anterior semicircular canal" EXACT [OBOL:automatic] synonym: "superior semicircular canal epithelial tissue" EXACT [OBOL:automatic] synonym: "superior semicircular canal epithelium" EXACT [OBOL:automatic] xref: EHDAA:7806 ! epithelium xref: VHOG:0001039 ! superior semicircular canal epithelium xref: RETIRED_EHDAA2:0001961 ! superior semicircular canal epithelium xref: EMAPA:17301 ! epithelium of superior semicircular canal (also: UBERON:0003241 'epithelium of utricle') intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001841 ! anterior semicircular canal [Term] id: UBERON:0003239 name: epithelium of posterior semicircular canal def: "An epithelium that is part of a posterior semicircular canal [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of posterior semicircular canal" EXACT [OBOL:automatic] synonym: "posterior semicircular canal epithelial tissue" EXACT [OBOL:automatic] synonym: "posterior semicircular canal epithelium" EXACT [OBOL:automatic] xref: EHDAA:7800 ! epithelium xref: VHOG:0000758 ! posterior semicircular canal epithelium xref: RETIRED_EHDAA2:0001491 ! posterior semicircular canal epithelium xref: EMAPA:17298 ! epithelium of posterior semicircular canal (also: UBERON:0003241 'epithelium of utricle') intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001842 ! posterior semicircular canal [Term] id: UBERON:0003240 name: epithelium of lateral semicircular canal def: "An epithelium that is part of a lateral semicircular canal [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lateral semicircular canal" EXACT [OBOL:automatic] synonym: "lateral semicircular canal epithelial tissue" EXACT [OBOL:automatic] synonym: "lateral semicircular canal epithelium" EXACT [OBOL:automatic] xref: EHDAA:7794 ! epithelium xref: VHOG:0000480 ! lateral semicircular canal epithelium xref: RETIRED_EHDAA2:0000922 ! lateral semicircular canal epithelium xref: EMAPA:17823 ! epithelium of lateral semicircular canal (also: UBERON:0003241 'epithelium of utricle') intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001843 ! lateral semicircular canal [Term] id: UBERON:0000054 ! macula name: macula def: "Thickened areas of the saccule or utricle where the termination of the vestibular nerve occurs[MESH,modified]." [MESH:A09.246.631.909.625.125] comment: Usage notes: this refers to the inner ear structure, not the macula of the retina. We follow ZFA in including a grouping class for the macula of utricle and sacule subset: uberon_slim synonym: "macula" EXACT [] synonym: "maculae" EXACT PLURAL [] synonym: "sensory macula" EXACT [ZFA:0000386] synonym: "sensory patch" EXACT [ZFA:0000386] synonym: "acoustic macula" RELATED [MESH:A09.246.631.909.625.125] synonym: "acoustic maculae" RELATED PLURAL [MESH:A09.246.631.909.625.125] xref: TAO:0000386 ! macula xref: ZFA:0000386 ! macula xref: GAID:777 ! acoustic maculae xref: MESH:A09.246.631.909.625.125 ! acoustic maculae is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001846 ! internal ear relationship: has_part GO:0070451 ! cell hair property_value: external_definition "Patches of thickened, pseudostratified epithelium of the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. Each patch has its own charcteristic shape and polarity pattern. (See Anatomical Atlas entry for sensory patches of the ear by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000386", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: has_relational_adjective "macular" xsd:string [Term] id: UBERON:0002212 name: macula of saccule of membranous labyrinth def: "The saccule is the smaller of the two vestibular sacs; it is globular in form, and lies in the recessus sphæricus near the opening of the scala vestibuli of the cochlea. Its anterior part exhibits an oval thickening, the macula of saccule (or saccular macula), to which are distributed the saccular filaments of the acoustic nerve. [WP,unvetted]." [Wikipedia:Macula_of_saccule] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "macula of saccule" EXACT [] synonym: "saccular macula of membranous labyrinth" EXACT [] synonym: "saccular maculs" RELATED [] synonym: "macula of membranous labyrinth saccule" EXACT [OBOL:automatic] synonym: "macula of sacculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "membranous labyrinth saccule macula" EXACT [OBOL:automatic] synonym: "saccule macula" EXACT [OBOL:automatic] synonym: "saccule of membranous labyrinth macula" EXACT [OBOL:automatic] synonym: "sacculus (labyrinthus vestibularis) macula" EXACT [OBOL:automatic] synonym: "macula saccule" EXACT [ZFA:0007000] synonym: "saccular macula" EXACT [ZFA:0007000] xref: FMA:74944 ! Macula of saccule of membranous labyrinth xref: MA:0001201 ! macula of saccule xref: ZFA:0007000 ! macula saccule xref: ncithesaurus:Macula_of_Saccule ! Macula of Saccule intersection_of: UBERON:0000054 ! macula intersection_of: part_of UBERON:0001854 ! saccule of membranous labyrinth relationship: part_of UBERON:0001854 ! saccule of membranous labyrinth synonym: "macula sacculi" EXACT LATIN [FMA:TA, FMA:74944] xref: SCTID:362572004 ! Entire macula of saccule xref: XAO:0004136 ! saccular macula xref: TAO:0007000 ! macula saccule synonym: "macula sacculi" RELATED LATIN [Wikipedia:Macula_of_saccule] xref: UMLS:C0229468 [Term] id: UBERON:0002214 name: macula of utricle of membranous labyrinth def: "The portion of the utricle which is lodged in the recess forms a sort of pouch or cul-de-sac, the floor and anterior wall of which are thickened, and form the macula of utricle (or utricular macula), which receives the utricular filaments of the vestibulocochlear nerve. [WP,unvetted]." [Wikipedia:Macula_of_utricle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim subset: vertebrate_core synonym: "macula of utricle" EXACT [] synonym: "utricular macula" RELATED [] synonym: "macula of membranous labyrinth utricle" EXACT [OBOL:automatic] synonym: "macula of utriculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "membranous labyrinth utricle macula" EXACT [OBOL:automatic] synonym: "utricle macula" EXACT [OBOL:automatic] synonym: "utricle of membranous labyrinth macula" EXACT [OBOL:automatic] synonym: "utriculus (labyrinthus vestibularis) macula" EXACT [OBOL:automatic] synonym: "macula utricle" EXACT [ZFA:0000030] xref: FMA:74960 ! Macula of utricle of membranous labyrinth xref: MA:0001203 ! macula of utricle xref: ZFA:0000030 ! macula utricle xref: ncithesaurus:Macula_of_Utricle ! Macula of Utricle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Bigotolith.jpg/200px-Bigotolith.jpg xref: EFO:0003474 ! macula utricle intersection_of: UBERON:0000054 ! macula intersection_of: part_of UBERON:0001853 ! utricle of membranous labyrinth synonym: "macula utriculi" EXACT LATIN [FMA:TA, FMA:74960] xref: SCTID:362568003 ! Entire macula of utricle xref: TAO:0000030 ! macula utricle synonym: "macula utriculi" RELATED LATIN [Wikipedia:Macula_of_utricle] xref: http://upload.wikimedia.org/wikipedia/commons/c/cb/Bigotolith.jpg xref: UMLS:C0229451 [Term] id: UBERON:0003241 ! epithelium of utricle name: epithelium of utricle def: "An epithelium that is part of a utricle of membranous labyrinth [Automatically generated definition]." [OBOL:automatic] comment: todo - check relationships w.r.t macula synonym: "epithelial tissue of membranous labyrinth utricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of utricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of utricle of membranous labyrinth" EXACT [OBOL:automatic] synonym: "epithelial tissue of utriculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "epithelium of membranous labyrinth utricle" EXACT [OBOL:automatic] synonym: "epithelium of utricle of membranous labyrinth" EXACT [OBOL:automatic] synonym: "epithelium of utriculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "membranous labyrinth utricle epithelial tissue" EXACT [OBOL:automatic] synonym: "membranous labyrinth utricle epithelium" EXACT [OBOL:automatic] synonym: "utricle epithelial tissue" EXACT [OBOL:automatic] synonym: "utricle epithelium" EXACT [OBOL:automatic] synonym: "utricle of membranous labyrinth epithelial tissue" EXACT [OBOL:automatic] synonym: "utricle of membranous labyrinth epithelium" EXACT [OBOL:automatic] synonym: "utriculus (labyrinthus vestibularis) epithelial tissue" EXACT [OBOL:automatic] synonym: "utriculus (labyrinthus vestibularis) epithelium" EXACT [OBOL:automatic] synonym: "epithelium of macula of utricle of membranous labyrinth" NARROW [FMA:75604] xref: EHDAA:4730 ! epithelium xref: VHOG:0000634 ! utricle epithelium xref: MA:0001204 ! utricle epithelium xref: RETIRED_EHDAA2:0002155 ! utricle epithelium xref: EMAPA:17295 ! epithelium of utricle xref: EMAPA:17298 ! epithelium of posterior semicircular canal (also: UBERON:0003239 'epithelium of posterior semicircular canal') xref: EMAPA:17301 ! epithelium of superior semicircular canal (also: UBERON:0003238 'epithelium of superior semicircular canal') xref: EMAPA:17820 ! epithelium of crus commune (also: UBERON:0005657 'crus commune epithelium') xref: EMAPA:17823 ! epithelium of lateral semicircular canal (also: UBERON:0003240 'epithelium of lateral semicircular canal') xref: FMA:75604 ! epithelium of macula of utricle of membranous labyrinth is_a: UBERON:0006934 ! sensory epithelium is_a: UBERON:0006932 {source="FMA"} ! vestibular epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001853 ! utricle of membranous labyrinth relationship: part_of UBERON:0002214 {source="FMA"} ! macula of utricle of membranous labyrinth relationship: has_part CL:0002316 {source="FMA"} ! supporting cell of vestibular epithelium relationship: has_part CL:1000379 {source="FMA"} ! type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth relationship: has_part CL:1000383 {source="FMA"} ! type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth [Term] id: UBERON:0003242 ! epithelium of saccule name: epithelium of saccule def: "An epithelium that is part of a saccule of membranous labyrinth [Automatically generated definition]." [OBOL:automatic] comment: todo - check relationships w.r.t macula synonym: "epithelial tissue of membranous labyrinth saccule" EXACT [OBOL:automatic] synonym: "epithelial tissue of saccule" EXACT [OBOL:automatic] synonym: "epithelial tissue of saccule of membranous labyrinth" EXACT [OBOL:automatic] synonym: "epithelial tissue of sacculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "epithelium of membranous labyrinth saccule" EXACT [OBOL:automatic] synonym: "epithelium of saccule of membranous labyrinth" EXACT [OBOL:automatic] synonym: "epithelium of sacculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "membranous labyrinth saccule epithelial tissue" EXACT [OBOL:automatic] synonym: "membranous labyrinth saccule epithelium" EXACT [OBOL:automatic] synonym: "saccule epithelial tissue" EXACT [OBOL:automatic] synonym: "saccule epithelium" EXACT [OBOL:automatic] synonym: "saccule of membranous labyrinth epithelial tissue" EXACT [OBOL:automatic] synonym: "saccule of membranous labyrinth epithelium" EXACT [OBOL:automatic] synonym: "sacculus (labyrinthus vestibularis) epithelial tissue" EXACT [OBOL:automatic] synonym: "sacculus (labyrinthus vestibularis) epithelium" EXACT [OBOL:automatic] synonym: "epithelium of macula of saccule of membranous labyrinth" RELATED [FMA:75605] xref: EHDAA:4724 ! epithelium xref: VHOG:0000633 ! saccule epithelium xref: MA:0001202 ! saccule epithelium xref: RETIRED_EHDAA2:0001771 ! saccule epithelium xref: EMAPA:17292 ! epithelium of saccule xref: FMA:75605 ! epithelium of macula of saccule of membranous labyrinth is_a: UBERON:0006934 ! sensory epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001854 ! saccule of membranous labyrinth relationship: has_part CL:0002316 {source="FMA"} ! supporting cell of vestibular epithelium relationship: has_part CL:1000380 {source="FMA"} ! type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth relationship: has_part CL:1000384 {source="FMA"} ! type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth [Term] id: UBERON:0009969 name: stato-acoustic epithelium comment: Editor note: required by CL is_a: UBERON:0006934 {source="FMA"} ! sensory epithelium xref: FMA:64804 ! stato-acoustic epithelium [Term] id: UBERON:0003243 name: epithelium of cochlear duct def: "An epithelium that is part of a cochlear duct of membranous labyrinth [Automatically generated definition]." [OBOL:automatic] synonym: "Reissner's canal epithelial tissue" EXACT [OBOL:automatic] synonym: "Reissner's canal epithelium" EXACT [OBOL:automatic] synonym: "cochlear duct epithelial tissue" EXACT [OBOL:automatic] synonym: "cochlear duct epithelium" EXACT [OBOL:automatic] synonym: "cochlear duct of membranous labyrinth epithelial tissue" EXACT [OBOL:automatic] synonym: "cochlear duct of membranous labyrinth epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of Reissner's canal" EXACT [OBOL:automatic] synonym: "epithelial tissue of cochlear duct" EXACT [OBOL:automatic] synonym: "epithelial tissue of cochlear duct of membranous labyrinth" EXACT [OBOL:automatic] synonym: "epithelium of Reissner's canal" EXACT [OBOL:automatic] synonym: "epithelium of cochlear duct of membranous labyrinth" EXACT [OBOL:automatic] xref: EHDAA:4722 ! epithelium xref: VHOG:0000640 ! cochlear duct epithelium xref: RETIRED_EHDAA2:0000264 ! cochlear duct epithelium xref: EMAPA:17600 ! epithelium of cochlear duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001855 ! cochlear duct of membranous labyrinth [Term] id: UBERON:0011272 name: embryonic skin basal layer comment: Editor notes: compare with 'stratum basale of epidermis'. This class is the source for many adult structures - see WP2062. See also: 'enveloping layer of ectoderm' synonym: "outer epithelium of body" RELATED [Wikipathways:WP2062] synonym: "basal cell layer of skin" RELATED [] is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument xref: EHDAA2:0001845 ! skin basal layer [Term] id: UBERON:0003244 name: epithelium of mammary gland def: "An epithelium that is part of a lactiferous gland [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lactiferous gland" EXACT [OBOL:automatic] synonym: "epithelial tissue of lobe of breast" EXACT [OBOL:automatic] synonym: "epithelial tissue of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "epithelial tissue of mammary gland" EXACT [OBOL:automatic] synonym: "epithelium of lobe of breast" EXACT [OBOL:automatic] synonym: "epithelium of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "lactiferous gland epithelial tissue" EXACT [OBOL:automatic] synonym: "lactiferous gland epithelium" EXACT [OBOL:automatic] synonym: "lobe of breast epithelial tissue" EXACT [OBOL:automatic] synonym: "lobe of breast epithelium" EXACT [OBOL:automatic] synonym: "lobe of mammary gland epithelial tissue" EXACT [OBOL:automatic] synonym: "lobe of mammary gland epithelium" EXACT [OBOL:automatic] synonym: "mammary gland epithelial tissue" EXACT [OBOL:automatic] synonym: "mammary gland epithelium" EXACT [OBOL:automatic] synonym: "mammary epithelium" EXACT [BTO:0001430] synonym: "epithelium of lactiferous gland" EXACT [FMA:74445] xref: EHDAA:6526 ! epithelium xref: FMA:74445 ! Epithelium of lactiferous gland xref: VHOG:0001088 ! mammary gland epithelium xref: MA:0000792 ! mammary gland epithelium xref: EHDAA2:0001057 ! mammary gland epithelium xref: BTO:0001430 ! mammary epithelium xref: EMAPA:17760 ! epithelium of mammary gland intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001911 ! lactiferous gland relationship: part_of UBERON:0005200 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="EHDAA2"} ! thoracic mammary gland relationship: develops_from UBERON:0011272 {source="EHDAA2", source="Wikipathways:WP2062"} ! skin basal layer xref: ncithesaurus:Mammary_Epithelium ! Mammary Epithelium xref: UMLS:C0596882 [Term] id: UBERON:0006954 name: mammary myoepithelium synonym: "lactiferous ductal myo-epithelium" EXACT [FMA:67798] synonym: "myoepithelium of lactiferous duct" EXACT [FMA:67798] synonym: "myo-epithelium of lactiferous duct" EXACT [FMA:67798] xref: BTO:0002310 ! mammary myoepithelium xref: FMA:67798 ! myo-epithelium of lactiferous duct intersection_of: UBERON:0000420 ! myoepithelium intersection_of: part_of UBERON:0001911 ! lactiferous gland relationship: has_part CL:1000419 {source="FMA"} ! myoepithelial cell of lactiferous duct def: "A myoepithelium that is part of a mammary gland." [OBOL:automatic] [Term] id: UBERON:0003246 name: epithelium of endolymphatic sac def: "An epithelium that is part of a endolymphatic sac [Automatically generated definition]." [OBOL:automatic] synonym: "endolymphatic sac epithelial tissue" EXACT [OBOL:automatic] synonym: "endolymphatic sac epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of endolymphatic sac" EXACT [OBOL:automatic] xref: EHDAA:7765 ! epithelium xref: RETIRED_EHDAA2:0000443 ! endolymphatic sac epithelium xref: EMAPA:17595 ! epithelium of endolymphatic sac intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002223 ! endolymphatic sac [Term] id: UBERON:0003247 name: epithelium of forearm def: "An epithelium that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "antebrachial region epithelial tissue" EXACT [OBOL:automatic] synonym: "antebrachial region epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of antebrachial region" EXACT [OBOL:automatic] synonym: "epithelial tissue of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "epithelial tissue of lower arm" EXACT [OBOL:automatic] synonym: "epithelial tissue of lower segment of arm" EXACT [OBOL:automatic] synonym: "epithelial tissue of zeugopod of arm" EXACT [OBOL:automatic] synonym: "epithelium of antebrachial region" EXACT [OBOL:automatic] synonym: "epithelium of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "epithelium of lower arm" EXACT [OBOL:automatic] synonym: "epithelium of lower segment of arm" EXACT [OBOL:automatic] synonym: "epithelium of zeugopod of arm" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb epithelial tissue" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb epithelium" EXACT [OBOL:automatic] synonym: "lower arm epithelial tissue" EXACT [OBOL:automatic] synonym: "lower arm epithelium" EXACT [OBOL:automatic] synonym: "lower segment of arm epithelial tissue" EXACT [OBOL:automatic] synonym: "lower segment of arm epithelium" EXACT [OBOL:automatic] synonym: "zeugopod of arm epithelial tissue" EXACT [OBOL:automatic] synonym: "zeugopod of arm epithelium" EXACT [OBOL:automatic] synonym: "arm middle limb segment epithelial tissue" EXACT [OBOL:automatic] synonym: "arm middle limb segment epithelium" EXACT [OBOL:automatic] synonym: "arm zeugopod epithelial tissue" EXACT [OBOL:automatic] synonym: "arm zeugopod epithelium" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment epithelial tissue" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment epithelium" EXACT [OBOL:automatic] synonym: "brachial region zeugopod epithelial tissue" EXACT [OBOL:automatic] synonym: "brachial region zeugopod epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of arm middle limb segment" EXACT [OBOL:automatic] synonym: "epithelial tissue of arm zeugopod" EXACT [OBOL:automatic] synonym: "epithelial tissue of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "epithelial tissue of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "epithelial tissue of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "epithelial tissue of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "epithelial tissue of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "epithelial tissue of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "epithelial tissue of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "epithelial tissue of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "epithelial tissue of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "epithelium of arm middle limb segment" EXACT [OBOL:automatic] synonym: "epithelium of arm zeugopod" EXACT [OBOL:automatic] synonym: "epithelium of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "epithelium of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "epithelium of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "epithelium of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "epithelium of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "epithelium of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "epithelium of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "epithelium of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "epithelium of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "middle limb segment of arm epithelial tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of arm epithelium" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region epithelial tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region epithelium" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb epithelial tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb epithelium" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment epithelial tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment epithelium" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod epithelial tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod epithelium" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region epithelial tissue" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region epithelium" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb epithelial tissue" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb epithelium" EXACT [OBOL:automatic] xref: EHDAA:4174 ! epithelium xref: EHDAA:6220 ! epithelium xref: VHOG:0001096 ! forearm epithelium xref: EHDAA2:0000554 ! forearm epithelium xref: EMAPA:17418 ! epithelium of forearm intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002386 ! forearm relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm [Term] id: UBERON:0010130 ! autopod plate name: autopod plate synonym: "limb plate" EXACT [] def: "the distal elements of the developing limb of vertebrates that will give rise to the pedal appendages (e.g. manus, pes, paw)" [MP:0004576, http://sourceforge.net/tracker/?func=detail&aid=3519614&group_id=76834&atid=1109502] intersection_of: UBERON:0002050 ! embryonic structure intersection_of: develops_into UBERON:0002470 ! autopod region relationship: develops_from UBERON:0004347 ! limb bud [Term] id: UBERON:0006871 ! footplate alt_id: UBERON:0004343 name: footplate comment: AO notes: EHDAA2 does not have a single class for footplate, but includes epithelium, mesenchyme and AER synonym: "foot plate" EXACT [] synonym: "foot disk" RELATED [] xref: EHDAA:5143 ! footplate xref: EHDAA:6096 ! footplate xref: EMAPA:17249 ! footplate xref: ncithesaurus:Foot_Plate ! Foot Plate intersection_of: UBERON:0010130 ! autopod plate intersection_of: develops_into UBERON:0002387 ! pes relationship: develops_from UBERON:0005418 ! hindlimb bud def: "An autopod plate that develops_into a pes." [OBOL:automatic] xref: UMLS:C1517291 [Term] id: UBERON:0003328 alt_id: UBERON:0005260 name: mesenchyme of footplate xref: EHDAA:5149 ! mesenchyme xref: EHDAA:6172 ! mesenchyme xref: EHDAA2:0000549 ! footplate mesenchyme xref: EMAPA:17252 ! mesenchyme of footplate xref: VHOG_RETIRED:0001055 synonym: "foot plate mesenchyme" EXACT [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006871 ! footplate relationship: develops_from UBERON:0003412 {source="EHDAA2"} ! hindlimb bud mesenchyme def: "Mesenchyme that is part of a footplate." [OBOL:automatic] [Term] id: UBERON:0006875 ! handplate name: handplate synonym: "hand plate" EXACT [] xref: EMAPA:17245 ! handplate xref: EHDAA:4194 ! handplate xref: EHDAA:6242 ! handplate xref: ncithesaurus:Hand_Plate ! Hand Plate intersection_of: UBERON:0010130 ! autopod plate intersection_of: develops_into UBERON:0002398 ! manus relationship: develops_from UBERON:0005417 ! forelimb bud def: "An autopod plate that develops_into a manus." [OBOL:automatic] xref: UMLS:C1512334 [Term] id: UBERON:0009523 name: mesenchyme of handplate subset: emapa_ehdaa2 synonym: "handplate mesenchyme" EXACT [EHDAA2:0000731] synonym: "hand plate mesenchyme" EXACT [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006875 ! handplate relationship: develops_from UBERON:0003413 {source="EHDAA2"} ! forelimb bud mesenchyme xref: EHDAA2:0000731 ! handplate mesenchyme xref: EMAPA:17248 ! mesenchyme of handplate def: "Mesenchyme that is part of a handplate." [OBOL:automatic] [Term] id: UBERON:0003248 name: epithelium of footplate xref: EHDAA:5145 ! epithelium xref: EHDAA:6144 ! epithelium xref: EHDAA2:0000548 ! footplate epithelium synonym: "footplate epithelium" EXACT [EHDAA2:0000548] synonym: "foot plate epithelium" EXACT [] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006871 ! footplate is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm def: "An epithelium that is part of a footplate." [OBOL:automatic] [Term] id: UBERON:0010332 name: epithelium of handplate is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006875 ! handplate relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm xref: EHDAA2:0000730 ! handplate epithelium synonym: "handplate epithelium" EXACT [EHDAA2:0000730] relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm def: "An epithelium that is part of a handplate." [OBOL:automatic] [Term] id: UBERON:0003249 ! epithelium of otic placode name: epithelium of otic placode def: "An epithelium that is part of a otic placode [Automatically generated definition]." [OBOL:automatic] comment: editor note - check ZFA, placemeant, appears to refer to both adult structures and primordium synonym: "epithelial tissue of otic placode" EXACT [OBOL:automatic] synonym: "otic placode epithelial tissue" EXACT [OBOL:automatic] synonym: "otic placode epithelium" EXACT [OBOL:automatic] synonym: "otic epithelium" EXACT [UBERON:cjm] xref: EHDAA:510 ! epithelium xref: VHOG:0000636 ! otic placode epithelium xref: EHDAA2:0001341 ! otic placode epithelium xref: EMAPA:16197 ! epithelium of otic placode xref: ZFA:0007068 ! otic epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003069 ! otic placode [Term] id: UBERON:0003255 name: obsolete ectoderm of embryo comment: deleted because the original definition was unclear. Me may reconstitute this and to distinguish extramebryonic from embryonic germ layers. See amniotic ectoderm and amniotic mesoderm synonym: "developmental tissue ectoderm" EXACT [OBOL:automatic] synonym: "ectoderm of developmental tissue" EXACT [OBOL:automatic] synonym: "embryo ectoderm" EXACT [OBOL:automatic] xref: EHDAA:132 ! ectoderm is_obsolete: true [Term] id: UBERON:0003256 name: obsolete endoderm of embryo comment: deleted because the original definition was unclear. Me may reconstitute this and to distinguish extramebryonic from embryonic germ layers. See amniotic ectoderm and amniotic mesoderm synonym: "developmental tissue endoderm" EXACT [OBOL:automatic] synonym: "embryo endoderm" EXACT [OBOL:automatic] synonym: "endoderm of developmental tissue" EXACT [OBOL:automatic] xref: EHDAA:94 ! endoderm is_obsolete: true [Term] id: UBERON:0003257 name: yolk sac endoderm comment: TODO - check xref: EHDAA:166 ! endoderm xref: VHOG:0000626 ! yolk sac endoderm xref: EHDAA2:0002215 ! yolk sac endoderm xref: EMAPA:16086 ! endoderm of yolk sac is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure intersection_of: UBERON:0000478 ! extraembryonic structure intersection_of: part_of UBERON:0001040 ! yolk sac intersection_of: develops_from UBERON:0000925 ! endoderm def: "An extraembryonic structure that develops_from a endoderm and is part of a yolk sac." [OBOL:automatic] [Term] id: UBERON:0003258 name: endoderm of foregut def: "An endoderm that is part of a foregut [Automatically generated definition]." [OBOL:automatic] comment: TODO - check synonym: "foregut endoderm" EXACT [OBOL:automatic] xref: EHDAA:524 ! endoderm xref: EHDAA2:0000566 ! lower foregut region endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001041 ! foregut [Term] id: UBERON:0003259 name: endoderm of midgut def: "An endoderm that is part of a midgut [Automatically generated definition]." [OBOL:automatic] comment: TODO - check synonym: "midgut endoderm" EXACT [OBOL:automatic] xref: EHDAA:987 ! endoderm xref: VHOG:0001080 ! midgut endoderm xref: RETIRED_EHDAA2:0001194 ! midgut endoderm xref: EMAPA:16257 ! endoderm of midgut intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001045 ! midgut [Term] id: UBERON:0003260 name: endoderm of hindgut def: "An endoderm that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] comment: TODO - check synonym: "hindgut endoderm" EXACT [OBOL:automatic] xref: EHDAA:979 ! endoderm xref: RETIRED_EHDAA2:0000781 ! hindgut endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001046 ! hindgut [Term] id: UBERON:0003264 name: mesoderm of yolk sac def: "A mesoderm that is part of a yolk sac [Automatically generated definition]." [OBOL:automatic] comment: TODO - check synonym: "yolk sac mesoderm" EXACT [OBOL:automatic] xref: EHDAA:168 ! mesoderm (also: UBERON:0000926 'mesoderm') xref: VHOG:0000617 ! yolk sac mesoderm xref: EMAPA:16087 ! mesoderm of yolk sac intersection_of: UBERON:0000926 ! mesoderm intersection_of: part_of UBERON:0001040 ! yolk sac [Term] id: UBERON:0004920 name: obsolete mesoderm of gonad def: "A mesoderm that is part of a gonad [Automatically generated definition]." [OBOL:automatic] synonym: "gonad mesoderm" EXACT [OBOL:automatic] synonym: "gonadal mesoderm" EXACT [OBOL:automatic] is_obsolete: true [Term] id: UBERON:0003267 name: tooth of upper jaw def: "A calcareous tooth that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] comment: Editor notes: Note that we follow EHDAA2 and consider teeth part of the jaw skeleton xref: EHDAA:8045 ! tooth xref: MA:0001909 ! upper jaw tooth xref: ncithesaurus:Upper_Jaw_Tooth ! Upper Jaw Tooth xref: EHDAA2:0002129 ! upper jaw tooth (also: UBERON:0009680 'set of upper jaw teeth') xref: EMAPA:17938 ! tooth of upper jaw intersection_of: UBERON:0001091 ! tooth intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0009680 ! set of upper jaw teeth relationship: attaches_to UBERON:0011597 ! bone of upper jaw synonym: "upper jaw tooth" EXACT [MA:0001909] xref: UMLS:C1710581 [Term] id: UBERON:0003268 name: tooth of lower jaw def: "A calcareous tooth that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "calcareous tooth of lower jaw" EXACT [OBOL:automatic] synonym: "calcareous tooth of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "dentine containing tooth of lower jaw" EXACT [OBOL:automatic] synonym: "dentine containing tooth of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "lower jaw calcareous tooth" EXACT [OBOL:automatic] synonym: "lower jaw dentine containing tooth" EXACT [OBOL:automatic] synonym: "lower jaw tooth" EXACT [OBOL:automatic] synonym: "lower jaw vertebrate tooth" EXACT [OBOL:automatic] synonym: "tooth of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "ventral mandibular arch calcareous tooth" EXACT [OBOL:automatic] synonym: "ventral mandibular arch dentine containing tooth" EXACT [OBOL:automatic] synonym: "ventral mandibular arch tooth" EXACT [OBOL:automatic] synonym: "ventral mandibular arch vertebrate tooth" EXACT [OBOL:automatic] synonym: "vertebrate tooth of lower jaw" EXACT [OBOL:automatic] synonym: "vertebrate tooth of ventral mandibular arch" EXACT [OBOL:automatic] xref: EHDAA:8009 ! tooth (also: UBERON:0001091 'calcareous tooth') xref: MA:0001907 ! lower jaw tooth xref: ncithesaurus:Lower_Jaw_Tooth ! Lower Jaw Tooth xref: EHDAA2:0001029 ! lower jaw tooth (also: UBERON:0009679 'set of lower jaw teeth') xref: EMAPA:17917 ! tooth of lower jaw intersection_of: UBERON:0001091 ! tooth intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: part_of UBERON:0009679 ! set of lower jaw teeth relationship: attaches_to UBERON:0004768 ! bone of lower jaw xref: UMLS:C1708757 [Term] id: UBERON:0009679 ! set of lower jaw teeth name: set of lower jaw teeth synonym: "arcus dentalis inferior" EXACT LATIN [FMA:TA] synonym: "lower dental arcade" EXACT [FMA:55635] synonym: "set of all lower teeth" EXACT [FMA:55635] intersection_of: UBERON:0009678 ! tooth row intersection_of: part_of UBERON:0003278 ! skeleton of lower jaw xref: EHDAA2:0001029 ! lower jaw teeth (also: UBERON:0003268 'tooth of lower jaw') xref: FMA:55635 ! mandibular dental arcade synonym: "lower jaw teeth" EXACT [EHDAA2:0001029] synonym: "mandibular dental arcade" RELATED [FMA:55635] def: "A tooth row that is part of a skeleton of lower jaw." [OBOL:automatic] [Term] id: UBERON:0009680 ! set of upper jaw teeth name: set of upper jaw teeth synonym: "arcus dentalis superior" EXACT LATIN [FMA:TA] synonym: "set of all upper teeth" EXACT [FMA:55634] synonym: "upper dental arcade" EXACT [FMA:55634] intersection_of: UBERON:0009678 ! tooth row intersection_of: part_of UBERON:0003277 ! skeleton of upper jaw xref: EHDAA2:0002129 ! upper jaw teeth (also: UBERON:0003267 'tooth of upper jaw') xref: FMA:55634 ! maxillary dental arcade synonym: "upper jaw teeth" EXACT [EHDAA2:0002129] synonym: "maxillary dental arcade" RELATED [FMA:55634] def: "A tooth row that is part of a skeleton of upper jaw." [OBOL:automatic] [Term] id: UBERON:0003269 name: skeletal muscle of eye def: "A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]." [OBOL:automatic] synonym: "eye skeletal muscle" EXACT [OBOL:automatic] synonym: "eye skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of eye" EXACT [OBOL:automatic] synonym: "eye skeletal muscle group" RELATED [EHDAA2:0000486] xref: EHDAA:2923 ! skeletal muscle (also: UBERON:0001134 'skeletal muscle tissue') xref: EHDAA2:0000486 ! eye skeletal muscle group xref: EMAPA:17844 ! skeletal muscle of eye intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0003270 name: skeletal muscle of leg def: "A portion of skeletal muscle tissue that is part of a tetrapod leg [Automatically generated definition]." [OBOL:automatic] synonym: "leg skeletal muscle" EXACT [OBOL:automatic] synonym: "leg skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of leg" EXACT [OBOL:automatic] xref: EHDAA:8291 ! skeletal muscle (also: UBERON:0001134 'skeletal muscle tissue') xref: RETIRED_EHDAA2:0000974 ! leg skeletal muscle xref: EMAPA:19318 ! skeletal muscle of lower leg xref: EMAPA:19144 ! skeletal muscle of upper leg intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0004466 {source="reference_0000032"} ! musculature of leg [Term] id: UBERON:0003271 name: skeletal muscle of pelvic girdle def: "A portion of skeletal muscle tissue that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic] synonym: "girdle-pelvic skeletal muscle" EXACT [OBOL:automatic] synonym: "girdle-pelvic skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "pelvic girdle bone skeletal muscle" EXACT [OBOL:automatic] synonym: "pelvic girdle bone skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "pelvic girdle skeletal muscle" EXACT [OBOL:automatic] synonym: "pelvic girdle skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of girdle-pelvic" EXACT [OBOL:automatic] synonym: "skeletal muscle of pelvic girdle bone" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of girdle-pelvic" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of pelvic girdle" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of pelvic girdle bone" EXACT [OBOL:automatic] xref: EHDAA:8326 ! skeletal muscle (also: UBERON:0001134 'skeletal muscle tissue') xref: RETIRED_EHDAA2:0001430 ! pelvic girdle skeletal muscle xref: EMAPA:18185 ! skeletal muscle of pelvic girdle of vertebral axis muscle system intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001271 ! pelvic girdle relationship: part_of UBERON:0004470 {source="reference_0000032"} ! musculature of pelvic girdle [Term] id: UBERON:0003272 name: skeletal muscle of arm def: "A portion of skeletal muscle tissue that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "arm skeletal muscle" EXACT [OBOL:automatic] synonym: "arm skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "brachial region skeletal muscle" EXACT [OBOL:automatic] synonym: "brachial region skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb skeletal muscle" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of brachial region" EXACT [OBOL:automatic] synonym: "skeletal muscle of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of arm" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of brachial region" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of proximal segment of free upper limb" EXACT [OBOL:automatic] xref: EHDAA:8277 ! skeletal muscle (also: UBERON:0001134 'skeletal muscle tissue') xref: RETIRED_EHDAA2:0000142 ! arm skeletal muscle xref: EMAPA:19107 ! skeletal muscle of upper arm intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0004474 {source="reference_0000032"} ! musculature of arm [Term] id: UBERON:0003276 name: skeleton of embryo def: "A skeletal system that is part of a embryo [Automatically generated definition]." [OBOL:automatic] synonym: "developmental tissue set of all bones" EXACT [OBOL:automatic] synonym: "developmental tissue set of bones of body" EXACT [OBOL:automatic] synonym: "developmental tissue skeletal system" EXACT [OBOL:automatic] synonym: "developmental tissue skeleton" EXACT [OBOL:automatic] synonym: "developmental tissue skeleton system" EXACT [OBOL:automatic] synonym: "embryo set of all bones" EXACT [OBOL:automatic] synonym: "embryo set of bones of body" EXACT [OBOL:automatic] synonym: "embryo skeletal system" EXACT [OBOL:automatic] synonym: "embryo skeleton" EXACT [OBOL:automatic] synonym: "embryo skeleton system" EXACT [OBOL:automatic] synonym: "set of all bones of developmental tissue" EXACT [OBOL:automatic] synonym: "set of all bones of embryo" EXACT [OBOL:automatic] synonym: "set of bones of body of developmental tissue" EXACT [OBOL:automatic] synonym: "set of bones of body of embryo" EXACT [OBOL:automatic] synonym: "skeletal system of developmental tissue" EXACT [OBOL:automatic] synonym: "skeletal system of embryo" EXACT [OBOL:automatic] synonym: "skeleton of developmental tissue" EXACT [OBOL:automatic] synonym: "skeleton system of developmental tissue" EXACT [OBOL:automatic] synonym: "skeleton system of embryo" EXACT [OBOL:automatic] xref: EHDAA:5047 ! skeleton (also: UBERON:0004288 'skeleton') xref: EMAPA:17213 ! skeleton of embryo intersection_of: UBERON:0001434 ! skeletal system intersection_of: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0003279 name: endothelium of trachea synonym: "endothelium of windpipe" EXACT [OBOL:automatic] synonym: "trachea endothelium" EXACT [OBOL:automatic] synonym: "windpipe endothelium" EXACT [OBOL:automatic] xref: EHDAA:3082 ! endothelium xref: RETIRED_EHDAA2:0002068 ! trachea endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0003126 ! trachea def: "An endothelium that is part of a trachea." [OBOL:automatic] [Term] id: UBERON:0003280 name: endothelium of main bronchus def: "An endothelium that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchus principalis endothelium" EXACT [OBOL:automatic] synonym: "endothelium of bronchus principalis" EXACT [OBOL:automatic] synonym: "endothelium of primary bronchus" EXACT [OBOL:automatic] synonym: "endothelium of principal bronchus" EXACT [OBOL:automatic] synonym: "main bronchus endothelium" EXACT [OBOL:automatic] synonym: "primary bronchus endothelium" EXACT [OBOL:automatic] synonym: "principal bronchus endothelium" EXACT [OBOL:automatic] xref: EHDAA:3076 ! endothelium xref: RETIRED_EHDAA2:0001046 ! main bronchus endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002182 ! main bronchus [Term] id: UBERON:0003885 name: mesometrium def: "A mesentery that is part of a uterus [Automatically generated definition]." [OBOL:automatic] synonym: "mesentery of uterus" RELATED [http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html, FMA:19816, MA:0002931] xref: FMA:19816 ! mesometrium [subclass: "region of mesentery"] xref: MA:0002931 ! mesometrium [part_of: "uterus"] intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 {source="MA"} ! uterus relationship: part_of UBERON:0012332 ! broad ligament of uterus xref: SCTID:250172001 ! Entire mesometrium relationship: part_of UBERON:0000459 {source="reference_0000032"} ! uterine wall [Term] id: UBERON:0003282 name: mesentery of heart def: "A mesentery that surrounds the heart." [MA:th] synonym: "heart mesentery" EXACT [OBOL:automatic] synonym: "mesocardium" RELATED [MA:0000098] xref: EHDAA:432 ! mesentery xref: VHOG:0000353 ! heart mesentery xref: RETIRED_EHDAA2:0000739 ! heart mesentery xref: EMAPA:16212 ! mesentery of heart intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0010277 name: mesocardium def: "The part of the embryonic mesentery which connects the embryonic heart with the body wall in front and the foregut behind." [http://medical-dictionary.thefreedictionary.com/mesocardium] comment: Editor notes: consider merging with heart mesentery is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000948 {source="MA"} ! heart relationship: part_of UBERON:0003282 ! mesentery of heart relationship: surrounded_by UBERON:0001074 ! pericardial cavity relationship: develops_from UBERON:0004873 {source="EHDAA2"} ! splanchnopleure property_value: has_relational_adjective "mesocardial" xsd:string xref: MA:0000098 ! mesocardium [Term] id: UBERON:0005601 name: dorsal mesocardium def: "the part of the mesocardium dorsal to the embryonic heart; it breaks down to form the transverse sinus of the pericardium." [MA:th] xref: MA:0000482 ! dorsal mesocardium xref: EHDAA2:0000413 ! dorsal mesocardium xref: EMAPA:16213 ! dorsal mesocardium xref: VHOG:0000432 ! dorsal mesocardium xref: EHDAA:434 ! dorsal mesocardium is_a: UBERON:0010277 {source="MA"} ! mesocardium relationship: part_of UBERON:0003282 {source="MA"} ! mesentery of heart relationship: develops_from UBERON:0004873 {source="EHDAA2"} ! splanchnopleure xref: SCTID:361454005 ! Dorsal mesocardium property_value: external_definition "The mesentery of the embryonic heart. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000432", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003283 name: mesentery of oesophagus def: "A mesentery that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophagus mesentery" EXACT [OBOL:automatic] synonym: "gullet mesentery" EXACT [OBOL:automatic] synonym: "mesentery of esophagus" EXACT [OBOL:automatic] synonym: "mesentery of gullet" EXACT [OBOL:automatic] synonym: "oesophagus mesentery" EXACT [OBOL:automatic] xref: EHDAA:2943 ! mesentery xref: VHOG:0000415 ! oesophagus mesentery xref: MA:0001569 ! esophagus mesentery xref: EHDAA2:0001288 ! oesophagus mesentery xref: EMAPA:16836 ! mesentery of oesophagus of foregut xref: EMAPA:18864 ! mesentery of oesophagus of gut intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001043 ! esophagus property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000415", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003284 name: mesentery of midgut def: "A mesentery that is part of a midgut [Automatically generated definition]." [OBOL:automatic] synonym: "midgut mesentery" EXACT [OBOL:automatic] xref: EHDAA:3031 ! mesentery xref: VHOG:0000413 ! midgut mesentery xref: EHDAA2:0001202 ! midgut mesentery xref: EMAPA:16721 ! mesentery of midgut xref: EMAPA:17039 ! mesentery of loop xref: EMAPA:17045 ! mesentery of rest of midgut xref: EMAPA:17197 ! mesentery of caudal part of duodenum of midgut intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001045 ! midgut property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000413", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003285 ! limb of embryo name: obsolete limb of embryo is_obsolete: true consider: UBERON:0002101 ! limb [Term] id: UBERON:0003286 name: foregut region of duodenum synonym: "foregut duodenum" EXACT [OBOL:automatic] xref: EHDAA:3830 ! duodenum xref: EHDAA2:0000560 ! foregut duodenum xref: EMAPA:17178 ! duodenum of foregut is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0002114 ! duodenum relationship: develops_from UBERON:0001041 ! foregut [Term] id: UBERON:0003287 name: midgut region of duodenum synonym: "midgut duodenum" EXACT [OBOL:automatic] xref: EHDAA:3937 ! duodenum xref: EHDAA2:0001189 ! midgut duodenum xref: EMAPA:17193 ! duodenum of midgut is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of UBERON:0002114 ! duodenum relationship: develops_from UBERON:0001045 ! midgut [Term] id: UBERON:0003288 name: meninx of midbrain comment: Editor notes: consider changing genus to subdivision of meninx def: "A meninx that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "meninges of midbrain" EXACT PLURAL [OBOL:automatic] synonym: "midbrain meninges" EXACT PLURAL [OBOL:automatic] synonym: "midbrain meninx" EXACT [OBOL:automatic] xref: EHDAA:3708 ! meninges xref: MA:0001058 ! midbrain meninges xref: VHOG:0000012 ! midbrain meninges xref: EHDAA2:0001174 ! midbrain meninges xref: RETIRED_EHDAA2:0001109 ! mesencephalon meninges xref: EMAPA:17791 ! meninges of midbrain intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0001891 ! midbrain synonym: "mesencephalon meninges" RELATED PLURAL [VHOG:0000012] property_value: external_definition "Meninges that are part of the midbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000012", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000012", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003289 name: meninx of telencephalon comment: Editor notes: consider changing genus to subdivision of meninx def: "A meninx that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "meninges of telencephalon" EXACT PLURAL [OBOL:automatic] synonym: "telencephalon meninges" EXACT PLURAL [OBOL:automatic] synonym: "telencephalon meninx" EXACT [OBOL:automatic] xref: EHDAA:5476 ! meninges xref: MA:0000979 ! telencephalon meninges xref: VHOG:0000010 ! telencephalon meninges xref: EHDAA2:0001990 ! telencephalon meninges xref: EMAPA:17774 ! meninges of telencephalon of forebrain (also: UBERON:0003548 'forebrain meninges') intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0001893 ! telencephalon property_value: external_definition "Meninges that are part of the telencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000010", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000010", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003290 name: meninx of diencephalon comment: Editor notes: consider changing genus to subdivision of meninx def: "A meninx that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "between brain meninges" EXACT [OBOL:automatic] synonym: "between brain meninx" EXACT [OBOL:automatic] synonym: "diencephalon meninges" EXACT [OBOL:automatic] synonym: "diencephalon meninx" EXACT [OBOL:automatic] synonym: "interbrain meninges" EXACT [OBOL:automatic] synonym: "interbrain meninx" EXACT [OBOL:automatic] synonym: "mature diencephalon meninges" EXACT [OBOL:automatic] synonym: "mature diencephalon meninx" EXACT [OBOL:automatic] synonym: "meninges of between brain" EXACT [OBOL:automatic] synonym: "meninges of interbrain" EXACT [OBOL:automatic] synonym: "meninges of mature diencephalon" EXACT [OBOL:automatic] synonym: "meninx of between brain" EXACT [OBOL:automatic] synonym: "meninges of diencephalon" EXACT [OBOL:automatic] synonym: "meninx of interbrain" EXACT [OBOL:automatic] synonym: "meninx of mature diencephalon" EXACT [OBOL:automatic] xref: EHDAA:5458 ! meninges xref: MA:0000826 ! diencephalon meninges xref: VHOG:0000009 ! diencephalon meninges xref: EHDAA2:0000399 ! diencephalon meninges xref: EMAPA:17764 ! meninges of diencephalon of forebrain (also: UBERON:0003548 'forebrain meninges') intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0001894 ! diencephalon property_value: external_definition "Meninges that are part of the diencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000009", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000009", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0010091 name: future hindbrain meninges is_a: UBERON:0007524 ! dense mesenchyme tissue relationship: part_of UBERON:0002028 ! hindbrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: develops_into UBERON:0003291 ! meninx of hindbrain xref: EHDAA2:0000610 ! future hindbrain meninges def: "A multi-tissue structure that develops_into a meninx of hindbrain." [OBOL:automatic] [Term] id: UBERON:0003291 name: meninx of hindbrain comment: Editor notes: consider changing genus to subdivision of meninx def: "A meninx that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] synonym: "hindbrain meninges" EXACT [OBOL:automatic] synonym: "hindbrain meninx" EXACT [OBOL:automatic] synonym: "meninges of hindbrain" EXACT [OBOL:automatic] xref: EHDAA:3688 ! meninges xref: MA:0000987 ! hindbrain meninges xref: VHOG:0000011 ! hindbrain meninges xref: EHDAA2:0000770 ! hindbrain meninges xref: EMAPA:17783 ! meninges of hindbrain of brain of central nervous system of nervous system of organ system intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0002028 ! hindbrain relationship: immediate_transformation_of UBERON:0010091 {evidence="definitional"} ! future hindbrain meninges synonym: "rhomencephalon meninges" RELATED PLURAL [VHOG:0000011] property_value: external_definition "Meninges that are part of the hindbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000011", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000011", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003292 name: meninx of spinal cord def: "A meninx that is part of a spinal cord [Automatically generated definition]." [OBOL:automatic] synonym: "spinal meninges" EXACT PLURAL [] synonym: "spinal meninx" EXACT [] synonym: "menines of spinal cord" EXACT PLURAL [] synonym: "meninges of spinal cord" EXACT [OBOL:automatic] synonym: "spinal cord meninges" EXACT [OBOL:automatic] synonym: "spinal cord meninx" EXACT [OBOL:automatic] xref: EHDAA:2865 ! meninges xref: MA:0001130 ! spinal cord meninges xref: VHOG:0000443 ! spinal cord meninges xref: ncithesaurus:Spinal_Meninges ! Spinal Meninges xref: EHDAA2:0001895 ! spinal cord meninges xref: EMAPA:17804 ! meninges of spinal cord of central nervous system of nervous system of organ system intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0002240 ! spinal cord xref: SCTID:181097002 ! Entire meninges of spinal cord property_value: external_definition "Meninges that are part of the spinal cord. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000443", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000443", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0037938 [Term] id: UBERON:0010047 alt_id: UBERON:0003293 name: oral gland def: "Gland of the epithelium lining the oral cavity. The most common are the salivary glands." [ISBN10:0073040584] comment: Note that Kardong classifies lacrimal glands here synonym: "buccal gland" EXACT [] synonym: "gland of oral opening" EXACT [OBOL:automatic] synonym: "gland of oral part of face" EXACT [OBOL:automatic] synonym: "gland of subdivision of mouth" EXACT [OBOL:automatic] synonym: "oral opening gland" EXACT [OBOL:automatic] synonym: "oral part of face gland" EXACT [OBOL:automatic] synonym: "oral region gland" EXACT [OBOL:automatic] synonym: "oral cavity gland" RELATED [OBOL:automatic] synonym: "subdivision of mouth gland" EXACT [OBOL:automatic] xref: EHDAA:2181 ! gland (also: UBERON:0002530 'gland') xref: VHOG:0000652 ! oral region gland xref: EHDAA2:0001327 ! oral region gland xref: EMAPA:16572 ! gland of stomatodaeum xref: EMAPA:16723 ! gland of oral region xref: SCTID:25421004 ! Buccal gland is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000165 ! mouth [Term] id: UBERON:0003294 name: gland of foregut def: "A gland that is part of a foregut [Automatically generated definition]." [OBOL:automatic] synonym: "foregut gland" EXACT [OBOL:automatic] xref: EHDAA:950 ! gland xref: VHOG:0000650 ! foregut gland xref: EHDAA2:0000567 ! foregut gland xref: EMAPA:16557 ! gland of foregut intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001041 ! foregut [Term] id: UBERON:0003296 name: gland of diencephalon def: "A gland that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "between brain gland" EXACT [OBOL:automatic] synonym: "diencephalon gland" EXACT [OBOL:automatic] synonym: "gland of between brain" EXACT [OBOL:automatic] synonym: "gland of interbrain" EXACT [OBOL:automatic] synonym: "gland of mature diencephalon" EXACT [OBOL:automatic] synonym: "interbrain gland" EXACT [OBOL:automatic] synonym: "mature diencephalon gland" EXACT [OBOL:automatic] xref: EHDAA:4475 ! gland (also: UBERON:0002530 'gland') xref: VHOG:0000653 ! diencephalon gland xref: EHDAA2:0000395 ! diencephalon gland xref: EMAPA:16646 ! gland of diencephalon of future forebrain xref: EMAPA:16897 ! gland of diencephalon of forebrain intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001894 ! diencephalon [Term] id: UBERON:0003297 name: gland of integumental system def: "A gland that is part of a integumental system [Automatically generated definition]." [OBOL:automatic] synonym: "integumental system gland" EXACT [OBOL:automatic] xref: EHDAA:6522 ! gland (also: UBERON:0002530 'gland') xref: VHOG:0000654 ! integumental system gland xref: MA:0000144 ! integumental system gland xref: EHDAA2:0000837 ! integumental system gland xref: EMAPA:17758 ! gland of integumental system intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002416 ! integumental system [Term] id: UBERON:0003298 name: roof plate of neural tube def: "A roof plate that is part of a neural tube [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "neural tube roof plate" EXACT [OBOL:automatic] synonym: "neural tube roofplate" EXACT [OBOL:automatic] synonym: "roofplate of neural tube" EXACT [OBOL:automatic] synonym: "roof plate neural tube region" EXACT [ZFA:0001436] xref: EHDAA:2891 ! roof plate xref: EHDAA:916 ! roof plate xref: ZFA:0001436 ! roof plate neural tube xref: VHOG:0000303 ! roof plate neural tube xref: EHDAA2:0001270 ! neural tube roof plate xref: EMAPA:16168 ! roof plate of neural tube of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16535 ! roof plate of neural tube of future spinal cord of central nervous system of nervous system of organ system intersection_of: UBERON:0000479 ! portion of tissue intersection_of: part_of UBERON:0003054 ! roof plate intersection_of: part_of UBERON:0001049 ! neural tube xref: TAO:0001436 ! roof plate neural tube synonym: "roof plate neural tube" EXACT [VHOG:0000303] [Term] id: UBERON:0003299 name: roof plate of midbrain def: "A roof plate that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "midbrain roof plate" EXACT [OBOL:automatic] synonym: "midbrain roofplate" EXACT [OBOL:automatic] synonym: "roofplate of midbrain" EXACT [OBOL:automatic] synonym: "roof plate midbrain region" EXACT [ZFA:0000355] xref: EHDAA:3712 ! roof plate xref: ZFA:0000355 ! roof plate midbrain xref: VHOG:0000772 ! roof plate midbrain xref: EHDAA2:0001177 ! midbrain roof plate xref: RETIRED_EHDAA2:0001111 ! mesencephalon roof plate xref: EMAPA:16981 ! roof plate of midbrain intersection_of: UBERON:0000479 ! portion of tissue intersection_of: part_of UBERON:0003054 ! roof plate intersection_of: part_of UBERON:0001891 ! midbrain xref: TAO:0000355 ! roof plate midbrain synonym: "roof plate midbrain" EXACT [VHOG:0000772] synonym: "roof plate mesencephalon" RELATED [VHOG:0000772] synonym: "roofplate midbrain" RELATED [VHOG:0000772] property_value: external_definition "Roof plate that is part of the midbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000772", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003300 name: roof plate of telencephalon def: "A roof plate that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "roofplate of telencephalon" EXACT [OBOL:automatic] synonym: "telencephalon roof plate" EXACT [OBOL:automatic] synonym: "telencephalon roofplate" EXACT [OBOL:automatic] xref: EHDAA:3512 ! roof plate xref: VHOG:0000774 ! roof plate telencephalon xref: EHDAA2:0001994 ! telencephalon roof plate xref: EMAPA:16657 ! roof plate of telencephalon of future forebrain intersection_of: UBERON:0000479 ! portion of tissue intersection_of: part_of UBERON:0003054 ! roof plate intersection_of: part_of UBERON:0001893 ! telencephalon synonym: "roof plate telencephalon" EXACT [VHOG:0000774] synonym: "roofplate medulla telencephalon" RELATED [VHOG:0000774] property_value: external_definition "Roof plate that is part of the telencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000774", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003301 name: roof plate of diencephalon def: "A roof plate that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "between brain roof plate" EXACT [OBOL:automatic] synonym: "between brain roofplate" EXACT [OBOL:automatic] synonym: "diencephalon roof plate" EXACT [OBOL:automatic] synonym: "diencephalon roofplate" EXACT [OBOL:automatic] synonym: "interbrain roof plate" EXACT [OBOL:automatic] synonym: "interbrain roofplate" EXACT [OBOL:automatic] synonym: "mature diencephalon roof plate" EXACT [OBOL:automatic] synonym: "mature diencephalon roofplate" EXACT [OBOL:automatic] synonym: "roof plate of between brain" EXACT [OBOL:automatic] synonym: "roof plate of interbrain" EXACT [OBOL:automatic] synonym: "roof plate of mature diencephalon" EXACT [OBOL:automatic] synonym: "roofplate of between brain" EXACT [OBOL:automatic] synonym: "roofplate of diencephalon" EXACT [OBOL:automatic] synonym: "roofplate of interbrain" EXACT [OBOL:automatic] synonym: "roofplate of mature diencephalon" EXACT [OBOL:automatic] synonym: "roof plate diencephalic region" EXACT [ZFA:0001358] xref: EHDAA:1979 ! roof plate xref: EHDAA:2657 ! roof plate xref: EHDAA:3494 ! roof plate xref: ZFA:0001358 ! roof plate diencephalon xref: VHOG:0000771 ! roof plate diencephalon xref: EHDAA2:0000402 ! diencephalon roof plate xref: EMAPA:16651 ! roof plate of diencephalon of future forebrain xref: EMAPA:16909 ! roof plate of diencephalon of forebrain intersection_of: UBERON:0000479 ! portion of tissue intersection_of: part_of UBERON:0003054 ! roof plate intersection_of: part_of UBERON:0001894 ! diencephalon xref: TAO:0001358 ! roof plate diencephalon synonym: "roof plate diencephalon" EXACT [VHOG:0000771] synonym: "roofplate medulla diencephalon" RELATED [VHOG:0000771] property_value: external_definition "Roof plate that is part of the diencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000771", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003302 name: roof plate of metencephalon def: "A roof plate that is part of a metencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "epencephalon-2 roof plate" EXACT [OBOL:automatic] synonym: "epencephalon-2 roofplate" EXACT [OBOL:automatic] synonym: "metencephalon roof plate" EXACT [OBOL:automatic] synonym: "metencephalon roofplate" EXACT [OBOL:automatic] synonym: "roof plate of epencephalon-2" EXACT [OBOL:automatic] synonym: "roofplate of epencephalon-2" EXACT [OBOL:automatic] synonym: "roofplate of metencephalon" EXACT [OBOL:automatic] xref: EHDAA:5524 ! roof plate xref: VHOG:0000770 ! roof plate metencephalon xref: EHDAA2:0001160 ! metencephalon roof plate xref: EMAPA:17098 ! roof plate of rhombomere 01 of metencephalon (also: UBERON:0005568 'rhombomere 1 roof plate') xref: EMAPA:17105 ! roof plate of rhombomere 02 of metencephalon (also: UBERON:0005572 'rhombomere 2 roof plate') intersection_of: UBERON:0000479 ! portion of tissue intersection_of: part_of UBERON:0003054 ! roof plate intersection_of: part_of UBERON:0001895 ! metencephalon synonym: "roof plate metencephalon" EXACT [VHOG:0000770] synonym: "roofplate medulla metencephalon" RELATED [VHOG:0000770] property_value: external_definition "Roof plate that is part of the metencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000770", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003303 name: roof plate of medulla oblongata def: "A roof plate that is part of a medulla oblongata [Automatically generated definition]." [OBOL:automatic] synonym: "bulb roof plate" EXACT [OBOL:automatic] synonym: "bulb roofplate" EXACT [OBOL:automatic] synonym: "medulla oblongata roof plate" EXACT [OBOL:automatic] synonym: "medulla oblongata roofplate" EXACT [OBOL:automatic] synonym: "medulla oblonmgata roof plate" EXACT [OBOL:automatic] synonym: "medulla oblonmgata roofplate" EXACT [OBOL:automatic] synonym: "metepencephalon roof plate" EXACT [OBOL:automatic] synonym: "metepencephalon roofplate" EXACT [OBOL:automatic] synonym: "roof plate of bulb" EXACT [OBOL:automatic] synonym: "roof plate of medulla oblonmgata" EXACT [OBOL:automatic] synonym: "roof plate of metepencephalon" EXACT [OBOL:automatic] synonym: "roofplate of bulb" EXACT [OBOL:automatic] synonym: "roofplate of medulla oblongata" EXACT [OBOL:automatic] synonym: "roofplate of medulla oblonmgata" EXACT [OBOL:automatic] synonym: "roofplate of metepencephalon" EXACT [OBOL:automatic] xref: EHDAA:7614 ! roof plate xref: VHOG:0000776 ! roof plate medulla oblongata xref: EHDAA2:0001099 ! medulla oblongata roof plate intersection_of: UBERON:0000479 ! portion of tissue intersection_of: part_of UBERON:0003054 ! roof plate intersection_of: part_of UBERON:0001896 ! medulla oblongata synonym: "roof plate medulla oblongata" EXACT [VHOG:0000776] synonym: "roofplate medulla oblongata" RELATED [VHOG:0000776] property_value: external_definition "Roof plate that is part of the medulla oblongata. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000776", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003307 name: floor plate of midbrain def: "A floor plate that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "floorplate of midbrain" EXACT [OBOL:automatic] synonym: "midbrain floor plate" EXACT [OBOL:automatic] synonym: "midbrain floorplate" EXACT [OBOL:automatic] synonym: "floor plate midbrain region" EXACT [ZFA:0001677] xref: EHDAA:3698 ! floor plate xref: ZFA:0001677 ! floor plate midbrain xref: VHOG:0000780 ! floor plate midbrain xref: EHDAA2:0001164 ! midbrain floor plate xref: RETIRED_EHDAA2:0001106 ! mesencephalon floor plate xref: EMAPA:16975 ! floor plate of midbrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0003079 ! floor plate intersection_of: part_of UBERON:0001891 ! midbrain xref: TAO:0002196 ! floor plate midbrain region property_value: external_definition "Floor plate that is part of the midbrain.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002196", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass multi-tissue structure (CARO:0000055) CHANGED TO: develops_from multi-tissue structure (UBERON:0000481)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002196", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: subclass multi-tissue structure (CARO:0000055) CHANGED TO: part_of multi-tissue structure (UBERON:0000481)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002196", date_retrieved="2012-08-14"} synonym: "floor plate midbrain" EXACT [VHOG:0000780] synonym: "floor plate mesencephalon" RELATED [VHOG:0000780] synonym: "floorplate midbrain" RELATED [VHOG:0000780] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0000780", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: EFO:0003567 ! basal plate midbrain region [Term] id: UBERON:0003308 name: floor plate of telencephalon def: "A floor plate that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "floorplate of telencephalon" EXACT [OBOL:automatic] synonym: "telencephalon floor plate" EXACT [OBOL:automatic] synonym: "telencephalon floorplate" EXACT [OBOL:automatic] synonym: "floor plate telencephalic region" EXACT [ZFA:0000914] synonym: "floorplate telencephalon" EXACT [ZFA:0000914] xref: EHDAA:3498 ! floor plate xref: ZFA:0000914 ! floor plate telencephalon xref: VHOG:0000783 ! floor plate telencephalon xref: EHDAA2:0001983 ! telencephalon floor plate xref: EMAPA:16655 ! floor plate of telencephalon of future forebrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0003079 ! floor plate intersection_of: part_of UBERON:0001893 ! telencephalon xref: TAO:0000914 ! floor plate telencephalon synonym: "floor plate telencephalon" EXACT [VHOG:0000783] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0000783", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003309 name: floor plate of diencephalon def: "A floor plate that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "between brain floor plate" EXACT [OBOL:automatic] synonym: "between brain floorplate" EXACT [OBOL:automatic] synonym: "diencephalon floor plate" EXACT [OBOL:automatic] synonym: "diencephalon floorplate" EXACT [OBOL:automatic] synonym: "floor plate of between brain" EXACT [OBOL:automatic] synonym: "floor plate of interbrain" EXACT [OBOL:automatic] synonym: "floor plate of mature diencephalon" EXACT [OBOL:automatic] synonym: "floorplate of between brain" EXACT [OBOL:automatic] synonym: "floorplate of diencephalon" EXACT [OBOL:automatic] synonym: "floorplate of interbrain" EXACT [OBOL:automatic] synonym: "floorplate of mature diencephalon" EXACT [OBOL:automatic] synonym: "interbrain floor plate" EXACT [OBOL:automatic] synonym: "interbrain floorplate" EXACT [OBOL:automatic] synonym: "mature diencephalon floor plate" EXACT [OBOL:automatic] synonym: "mature diencephalon floorplate" EXACT [OBOL:automatic] synonym: "floor plate diencephalic region" EXACT [ZFA:0000871] synonym: "floorplate diencephalon" EXACT [ZFA:0000871] xref: EHDAA:1975 ! floor plate xref: EHDAA:2651 ! floor plate xref: EHDAA:3480 ! floor plate xref: ZFA:0000871 ! floor plate diencephalon xref: VHOG:0000782 ! floor plate diencephalon xref: EHDAA2:0000388 ! diencephalon floor plate xref: EMAPA:16645 ! floor plate of diencephalon of future forebrain xref: EMAPA:16903 ! floor plate of diencephalon of forebrain intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0003079 ! floor plate intersection_of: part_of UBERON:0001894 ! diencephalon xref: TAO:0000871 ! floor plate diencephalon synonym: "floor plate diencephalon" EXACT [VHOG:0000782] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0000782", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003310 name: floor plate of metencephalon def: "A floor plate that is part of a metencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "epencephalon-2 floor plate" EXACT [OBOL:automatic] synonym: "epencephalon-2 floorplate" EXACT [OBOL:automatic] synonym: "floor plate of epencephalon-2" EXACT [OBOL:automatic] synonym: "floorplate of epencephalon-2" EXACT [OBOL:automatic] synonym: "floorplate of metencephalon" EXACT [OBOL:automatic] synonym: "metencephalon floor plate" EXACT [OBOL:automatic] synonym: "metencephalon floorplate" EXACT [OBOL:automatic] xref: EHDAA:5500 ! floor plate xref: VHOG:0000784 ! floor plate metencephalon xref: EHDAA2:0001158 ! metencephalon floor plate xref: EMAPA:17093 ! floor plate of rhombomere 01 of metencephalon (also: UBERON:0005566 'rhombomere 1 floor plate') xref: EMAPA:17100 ! floor plate of rhombomere 02 of metencephalon (also: UBERON:0005570 'rhombomere 2 floor plate') xref: EMAPA:17258 ! floor plate of metencephalon intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0003079 ! floor plate intersection_of: part_of UBERON:0001895 ! metencephalon synonym: "floor plate metencephalon" EXACT [VHOG:0000784] synonym: "floorplate metencephalon" RELATED [VHOG:0000784] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0000784", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003311 name: floor plate of medulla oblongata def: "A floor plate that is part of a medulla oblongata [Automatically generated definition]." [OBOL:automatic] synonym: "bulb floor plate" EXACT [OBOL:automatic] synonym: "bulb floorplate" EXACT [OBOL:automatic] synonym: "floor plate of bulb" EXACT [OBOL:automatic] synonym: "floor plate of medulla oblonmgata" EXACT [OBOL:automatic] synonym: "floor plate of metepencephalon" EXACT [OBOL:automatic] synonym: "floorplate of bulb" EXACT [OBOL:automatic] synonym: "floorplate of medulla oblongata" EXACT [OBOL:automatic] synonym: "floorplate of medulla oblonmgata" EXACT [OBOL:automatic] synonym: "floorplate of metepencephalon" EXACT [OBOL:automatic] synonym: "medulla oblongata floor plate" EXACT [OBOL:automatic] synonym: "medulla oblongata floorplate" EXACT [OBOL:automatic] synonym: "medulla oblonmgata floor plate" EXACT [OBOL:automatic] synonym: "medulla oblonmgata floorplate" EXACT [OBOL:automatic] synonym: "metepencephalon floor plate" EXACT [OBOL:automatic] synonym: "metepencephalon floorplate" EXACT [OBOL:automatic] xref: EHDAA:7590 ! floor plate xref: VHOG:0000786 ! floor plate medulla oblongata xref: EHDAA2:0001097 ! medulla oblongata floor plate xref: EMAPA:17551 ! floor plate of medulla oblongata intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0003079 ! floor plate intersection_of: part_of UBERON:0001896 ! medulla oblongata synonym: "floor plate medulla oblongata" EXACT [VHOG:0000786] synonym: "floorplate medulla oblongata" RELATED [VHOG:0000786] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0000786", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003312 name: mesenchyme of testis def: "Mesenchyme that is part of a testis [Automatically generated definition]." [OBOL:automatic] synonym: "testis mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:8150 ! mesenchyme xref: VHOG:0001442 ! testis mesenchyme xref: EHDAA2:0002010 ! testis mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000473 ! testis [Term] id: UBERON:0009920 name: optic neural crest is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest xref: EHDAA2:0001315 ! optic neural crest xref: EHDAA:1122 ! optic neural crest [Term] id: UBERON:0003314 name: eye mesenchyme synonym: "mesenchyme of eye" EXACT [OBOL:automatic] comment: todo - change mesenchyme relationships to precursor_of xref: EHDAA:2910 ! mesenchyme xref: VHOG:0001084 ! eye mesenchyme xref: EHDAA2:0000485 ! eye mesenchyme xref: EMAPA:16324 ! mesenchyme of optic eminence (also: UBERON:0005702 'optic eminence mesenchyme') xref: EMAPA:16673 ! mesenchyme of eye xref: EMAPA:17833 ! mesenchyme of lower of eyelid xref: EMAPA:17836 ! mesenchyme of upper of eyelid intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: develops_from UBERON:0009920 {source="EHDAA2"} ! optic neural crest def: "Mesenchyme that is part of a camera-type eye." [OBOL:automatic] [Term] id: UBERON:0003315 name: mesenchyme of ovary def: "Mesenchyme that is part of a ovary [Automatically generated definition]." [OBOL:automatic] synonym: "ovary mesenchyme" EXACT [OBOL:automatic] synonym: "female reproductive system gonad mesenchyme" EXACT [OBOL:automatic] synonym: "female reproductive system gonada mesenchyme" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system mesenchyme" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of female reproductive system gonad" EXACT [OBOL:automatic] synonym: "mesenchyme of female reproductive system gonada" EXACT [OBOL:automatic] synonym: "mesenchyme of gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "mesenchyme of gonada of female reproductive system" EXACT [OBOL:automatic] xref: EHDAA:8128 ! mesenchyme xref: VHOG:0001441 ! ovary mesenchyme xref: EHDAA2:0001362 ! ovary mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000992 ! female gonad [Term] id: UBERON:0003316 name: mesenchyme of yolk sac def: "Mesenchyme that is part of a yolk sac [Automatically generated definition]." [OBOL:automatic] synonym: "yolk sac mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:205 ! mesenchyme xref: VHOG:0000503 ! yolk sac mesenchyme xref: EHDAA2:0002216 ! yolk sac mesenchyme xref: EMAPA:16267 ! mesenchyme of yolk sac intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001040 ! yolk sac [Term] id: UBERON:0003318 name: mesenchyme of elbow def: "Mesenchyme that is part of a elbow [Automatically generated definition]." [OBOL:automatic] synonym: "cubital region mesenchyme" EXACT [OBOL:automatic] synonym: "elbow mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of cubital region" EXACT [OBOL:automatic] xref: EHDAA:4170 ! mesenchyme xref: EHDAA:6216 ! mesenchyme xref: VHOG:0001075 ! elbow mesenchyme xref: EHDAA2:0000432 ! elbow mesenchyme xref: EMAPA:17416 ! mesenchyme of elbow intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001461 ! elbow [Term] id: UBERON:0003319 ! mesenchyme of carpal region name: mesenchyme of carpal region def: "Mesenchyme of the carpal region that conributes to the carpal skeleton." [UBERON:cjm] synonym: "carpal region mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of wrist" EXACT [OBOL:automatic] synonym: "wrist mesenchyme" EXACT [OBOL:automatic] synonym: "carpus mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:5200 ! mesenchyme xref: EHDAA2:0000220 ! carpal region mesenchyme xref: EMAPA:18485 ! carpus of mesenchyme of fore-paw intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0010695 ! mesenchyme of tarsal region name: mesenchyme of tarsal region def: "Mesenchyme of the carpal region that conributes to the tarsal skeleton." [UBERON:cjm] xref: EMAPA:18500 ! tarsus of mesenchyme of hind-paw intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004454 ! tarsal region [Term] id: UBERON:0003320 name: mesenchyme of hip def: "Mesenchyme that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "hip mesenchyme" EXACT [OBOL:automatic] synonym: "hip region mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of hip region" EXACT [OBOL:automatic] synonym: "mesenchyme of regio coxae" EXACT [OBOL:automatic] synonym: "regio coxae mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:5157 ! mesenchyme xref: EHDAA:6182 ! mesenchyme xref: VHOG:0001029 ! hip mesenchyme xref: EHDAA2:0000786 ! hip mesenchyme xref: EMAPA:17492 ! mesenchyme of hip intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001464 ! hip [Term] id: UBERON:0003321 name: mesenchyme of knee def: "Mesenchyme that is part of a knee [Automatically generated definition]." [OBOL:automatic] synonym: "knee mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:5163 ! mesenchyme xref: EHDAA:6188 ! mesenchyme xref: VHOG:0001070 ! knee mesenchyme xref: EHDAA2:0000898 ! knee mesenchyme xref: EMAPA:17495 ! mesenchyme of knee intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001465 ! knee [Term] id: UBERON:0003322 name: mesenchyme of shoulder def: "Mesenchyme that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "shoulder mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:4184 ! mesenchyme xref: EHDAA:6232 ! mesenchyme xref: VHOG:0001035 ! shoulder mesenchyme xref: EHDAA2:0001837 ! shoulder mesenchyme xref: EMAPA:17423 ! mesenchyme of shoulder intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001467 ! shoulder [Term] id: UBERON:0003323 name: mesenchyme of upper jaw def: "Mesenchyme that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "palatoquadrate arch mesenchyme" EXACT [OBOL:automatic] synonym: "upper jaw mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:8031 ! mesenchyme xref: VHOG:0001099 ! upper jaw mesenchyme xref: EHDAA2:0002124 ! upper jaw mesenchyme xref: EMAPA:17929 ! mesenchyme of upper jaw intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: develops_from UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme [Term] id: UBERON:0003324 name: mesenchyme of lower jaw def: "Mesenchyme that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "lower jaw mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "ventral mandibular arch mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:8003 ! mesenchyme xref: VHOG:0001069 ! lower jaw mesenchyme xref: EHDAA2:0001024 ! lower jaw mesenchyme xref: EMAPA:17916 ! mesenchyme of lower jaw intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: develops_from UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme [Term] id: UBERON:0003325 name: mesenchyme of pinna def: "Mesenchyme that is part of a pinna [Automatically generated definition]." [OBOL:automatic] synonym: "auricle mesenchyme" EXACT [OBOL:automatic] synonym: "auricle of ear mesenchyme" EXACT [OBOL:automatic] synonym: "auricle of external ear mesenchyme" EXACT [OBOL:automatic] synonym: "auricula (auris externa) mesenchyme" EXACT [OBOL:automatic] synonym: "auricula mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of auricle" EXACT [OBOL:automatic] synonym: "mesenchyme of auricle of ear" EXACT [OBOL:automatic] synonym: "mesenchyme of auricle of external ear" EXACT [OBOL:automatic] synonym: "mesenchyme of auricula" EXACT [OBOL:automatic] synonym: "mesenchyme of auricula (auris externa)" EXACT [OBOL:automatic] synonym: "mesenchyme of pinna of ear" EXACT [OBOL:automatic] synonym: "pinna mesenchyme" EXACT [OBOL:automatic] synonym: "pinna of ear mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:8981 ! mesenchyme xref: VHOG:0000747 ! pinna mesenchyme xref: EHDAA2:0001469 ! pinna mesenchyme xref: EMAPA:17591 ! mesenchyme of pinna intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001757 ! pinna [Term] id: UBERON:0003326 name: mesenchyme of mammary gland synonym: "mammary mesenchyme" EXACT [] synonym: "lactiferous gland mesenchyme" EXACT [OBOL:automatic] synonym: "lobe of breast mesenchyme" EXACT [OBOL:automatic] synonym: "lobe of mammary gland mesenchyme" EXACT [OBOL:automatic] synonym: "mammary gland mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of lactiferous gland" EXACT [OBOL:automatic] synonym: "mesenchyme of lobe of breast" EXACT [OBOL:automatic] synonym: "mesenchyme of lobe of mammary gland" EXACT [OBOL:automatic] xref: EHDAA:6528 ! mesenchyme xref: VHOG:0001087 ! mammary gland mesenchyme xref: EHDAA2:0001058 ! mammary gland mesenchyme xref: EMAPA:17761 ! mesenchyme of mammary gland intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001911 ! lactiferous gland def: "Mesenchyme that is part of a mammary gland." [OBOL:automatic] [Term] id: UBERON:0003327 name: mesenchyme of forearm def: "Mesenchyme that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "antebrachial region mesenchyme" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb mesenchyme" EXACT [OBOL:automatic] synonym: "lower arm mesenchyme" EXACT [OBOL:automatic] synonym: "lower segment of arm mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of antebrachial region" EXACT [OBOL:automatic] synonym: "mesenchyme of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "mesenchyme of lower arm" EXACT [OBOL:automatic] synonym: "mesenchyme of lower segment of arm" EXACT [OBOL:automatic] synonym: "mesenchyme of zeugopod of arm" EXACT [OBOL:automatic] synonym: "zeugopod of arm mesenchyme" EXACT [OBOL:automatic] synonym: "arm middle limb segment mesenchyme" EXACT [OBOL:automatic] synonym: "arm zeugopod mesenchyme" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment mesenchyme" EXACT [OBOL:automatic] synonym: "brachial region zeugopod mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of arm middle limb segment" EXACT [OBOL:automatic] synonym: "mesenchyme of arm zeugopod" EXACT [OBOL:automatic] synonym: "mesenchyme of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "mesenchyme of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "mesenchyme of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "mesenchyme of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "mesenchyme of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "mesenchyme of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "mesenchyme of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "mesenchyme of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "mesenchyme of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "middle limb segment of arm mesenchyme" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region mesenchyme" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb mesenchyme" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment mesenchyme" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod mesenchyme" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region mesenchyme" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb mesenchyme" EXACT [OBOL:automatic] xref: EHDAA:4176 ! mesenchyme xref: EHDAA:6222 ! mesenchyme xref: VHOG:0000504 ! forearm mesenchyme xref: EHDAA2:0000555 ! forearm mesenchyme xref: EMAPA:17419 ! mesenchyme of forearm intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0002386 {source="EMAPA"} ! forelimb zeugopod [Term] id: UBERON:0003329 name: submucosa of anal canal def: "A submucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic] synonym: "anal canal submucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically submucosa" EXACT [OBOL:automatic] synonym: "anal region submucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal submucosa" EXACT [OBOL:automatic] synonym: "submucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "submucosa of anal region" EXACT [OBOL:automatic] synonym: "submucosa of anatomical anal canal" EXACT [OBOL:automatic] xref: EMAPA:27535 ! submucosa of anal canal xref: FMA:85399 ! Submucosa of anal canal intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000159 ! anal canal xref: SCTID:7892006 ! Structure of submucosa of anal canal xref: EMAPA:27217 ! submucosa of caudal part of anal canal xref: EMAPA:27227 ! submucosa of rostral part of anal canal [Term] id: UBERON:0003330 name: submucosa of rectum def: "The submucous layer of the wall of the rectum." [BTO:0002114] synonym: "rectum submucosa" EXACT [OBOL:automatic] synonym: "rectal submucosa" EXACT [FMA:15034] synonym: "tela submucosa recti" EXACT LATIN [BTO:0002114] xref: EMAPA:27083 ! submucosa of rectum of hindgut xref: EMAPA:27323 ! submucosa of rectum of gut xref: FMA:15034 ! Submucosa of rectum intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001052 ! rectum xref: SCTID:71683001 ! Rectal submucosa xref: BTO:0002114 ! tela submucosa recti [Term] id: UBERON:0003331 name: submucosa of colon def: "A submucosa that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon submucosa" EXACT [OBOL:automatic] synonym: "large bowel submucosa" EXACT [OBOL:automatic] synonym: "submucosa of large bowel" EXACT [OBOL:automatic] synonym: "colonic submucosa" EXACT [FMA:14985] xref: EMAPA:27379 ! submucosa of colon xref: FMA:14985 ! Submucosa of colon intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001155 ! colon xref: SCTID:61647009 ! Colonic submucosa [Term] id: UBERON:0003332 name: submucosa of duodenum def: "A submucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "duodenum submucosa" EXACT [OBOL:automatic] synonym: "doudenal submucosa" EXACT [FMA:14943] synonym: "duodenal submucosa" EXACT [FMA:14943] xref: EMAPA:27239 ! submucosa of duodenum of gut xref: FMA:14943 ! Submucosa of duodenum intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002114 ! duodenum xref: SCTID:76519004 ! Duodenal submucosa xref: EMAPA:27027 ! submucosa of rostral part of duodenum of foregut xref: EMAPA:27097 ! submucosa of caudal part of duodenum of midgut [Term] id: UBERON:0003333 name: submucosa of jejunum def: "A submucosa that is part of a jejunum [Automatically generated definition]." [OBOL:automatic] synonym: "jejunum submucosa" EXACT [OBOL:automatic] synonym: "jejunal submucosa" EXACT [FMA:14950] xref: EMAPA:27111 ! submucosa of jejunum of midgut xref: EMAPA:27351 ! submucosa of jejunum of gut xref: FMA:14950 ! Submucosa of jejunum intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002115 ! jejunum xref: SCTID:70192009 ! Jejunal submucosa [Term] id: UBERON:0003334 name: serosa of rectum def: "A serous membrane that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "rectum serosa" EXACT [OBOL:automatic] synonym: "rectum serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of rectum" EXACT [OBOL:automatic] synonym: "rectal serosa" EXACT [FMA:15039] synonym: "visceral peritoneum of rectum" EXACT [FMA:15039] xref: EMAPA:27087 ! serosa of rectum of hindgut xref: EMAPA:27331 ! serosa of rectum of gut xref: FMA:15039 ! Serosa of rectum intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003335 name: serosa of colon def: "A serous membrane that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon serosa" EXACT [OBOL:automatic] synonym: "colon serous membrane" EXACT [OBOL:automatic] synonym: "large bowel serosa" EXACT [OBOL:automatic] synonym: "large bowel serous membrane" EXACT [OBOL:automatic] synonym: "serosa of large bowel" EXACT [OBOL:automatic] synonym: "serous membrane of colon" EXACT [OBOL:automatic] synonym: "serous membrane of large bowel" EXACT [OBOL:automatic] synonym: "colonic serosa" EXACT [FMA:14990] synonym: "visceral peritoneum of colon" EXACT [FMA:14990] xref: EMAPA:27387 ! serosa of colon xref: FMA:14990 ! Serosa of colon intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001155 ! colon xref: SCTID:90132000 ! Colonic serosa [Term] id: UBERON:0003336 name: serosa of duodenum def: "A serous membrane that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] comment: Histology notes: 1st part serosa, 2nd - 4th adventitia synonym: "duodenum serosa" EXACT [OBOL:automatic] synonym: "duodenum serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of duodenum" EXACT [OBOL:automatic] synonym: "doudenal serosa" EXACT [FMA:14948] synonym: "duodenal serosa" EXACT [FMA:14948] synonym: "visceral peritoneum of duodenum" EXACT [FMA:14948] xref: EMAPA:27247 ! serosa of duodenum of gut xref: FMA:14948 ! Serosa of duodenum intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002114 ! duodenum xref: SCTID:1236009 ! Duodenal serosa [Term] id: UBERON:0003337 name: serosa of jejunum def: "A serous membrane that is part of a jejunum [Automatically generated definition]." [OBOL:automatic] synonym: "jejunum serosa" EXACT [OBOL:automatic] synonym: "jejunum serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of jejunum" EXACT [OBOL:automatic] synonym: "jejunal serosa" EXACT [FMA:14955] synonym: "visceral peritoneum of jejunum" EXACT [FMA:14955] xref: EMAPA:27115 ! serosa of jejunum of midgut xref: EMAPA:27359 ! serosa of jejunum of gut xref: FMA:14955 ! Serosa of jejunum intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002115 ! jejunum [Term] id: UBERON:0003340 name: obsolete urethra of urogenital sinus is_obsolete: true consider: EMAPA:30891 ! urethra of urogenital sinus of urinary system [Term] id: UBERON:0003341 name: obsolete urethra of urinary system is_obsolete: true [Term] id: UBERON:0003342 name: mucosa of anal canal def: "A mucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic] synonym: "anal canal mucosa" EXACT [OBOL:automatic] synonym: "anal canal mucosa of organ" EXACT [OBOL:automatic] synonym: "anal canal mucous membrane" EXACT [OBOL:automatic] synonym: "anal canal organ mucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucosa of organ" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucous membrane" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically organ mucosa" EXACT [OBOL:automatic] synonym: "anal region mucosa" EXACT [OBOL:automatic] synonym: "anal region mucosa of organ" EXACT [OBOL:automatic] synonym: "anal region mucous membrane" EXACT [OBOL:automatic] synonym: "anal region organ mucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucosa of organ" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucous membrane" EXACT [OBOL:automatic] synonym: "anatomical anal canal organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucosa of anal region" EXACT [OBOL:automatic] synonym: "mucosa of anatomical anal canal" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal canal" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal region" EXACT [OBOL:automatic] synonym: "mucosa of organ of anatomical anal canal" EXACT [OBOL:automatic] synonym: "mucous membrane of anal canal" EXACT [OBOL:automatic] synonym: "mucous membrane of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucous membrane of anal region" EXACT [OBOL:automatic] synonym: "mucous membrane of anatomical anal canal" EXACT [OBOL:automatic] synonym: "organ mucosa of anal canal" EXACT [OBOL:automatic] synonym: "organ mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "organ mucosa of anal region" EXACT [OBOL:automatic] synonym: "organ mucosa of anatomical anal canal" EXACT [OBOL:automatic] synonym: "anal mucosa" EXACT [FMA:74654] synonym: "anal mucous membrane" EXACT [FMA:74654] xref: EMAPA:27531 ! mucosa of anal canal xref: FMA:74654 ! Mucosa of anal canal intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000159 ! anal canal xref: ncithesaurus:Anal_Mucosa ! Anal Mucosa xref: SCTID:362170004 ! Entire mucous membrane of anal canal xref: UMLS:C0227414 [Term] id: UBERON:0003343 name: mucosa of oral region def: "A mucosa that is part of a oral opening [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of oral opening" EXACT [OBOL:automatic] synonym: "mucosa of oral part of face" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral opening" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral part of face" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral region" EXACT [OBOL:automatic] synonym: "mucosa of organ of subdivision of mouth" EXACT [OBOL:automatic] synonym: "mucosa of subdivision of mouth" EXACT [OBOL:automatic] synonym: "mucous membrane of oral opening" EXACT [OBOL:automatic] synonym: "mucous membrane of oral part of face" EXACT [OBOL:automatic] synonym: "mucous membrane of oral region" EXACT [OBOL:automatic] synonym: "mucous membrane of subdivision of mouth" EXACT [OBOL:automatic] synonym: "oral opening mucosa" EXACT [OBOL:automatic] synonym: "oral opening mucosa of organ" EXACT [OBOL:automatic] synonym: "oral opening mucous membrane" EXACT [OBOL:automatic] synonym: "oral opening organ mucosa" EXACT [OBOL:automatic] synonym: "oral part of face mucosa" EXACT [OBOL:automatic] synonym: "oral part of face mucosa of organ" EXACT [OBOL:automatic] synonym: "oral part of face mucous membrane" EXACT [OBOL:automatic] synonym: "oral part of face organ mucosa" EXACT [OBOL:automatic] synonym: "oral region mucosa" EXACT [OBOL:automatic] synonym: "oral region mucosa of organ" EXACT [OBOL:automatic] synonym: "oral region mucous membrane" EXACT [OBOL:automatic] synonym: "oral region organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of oral opening" EXACT [OBOL:automatic] synonym: "organ mucosa of oral part of face" EXACT [OBOL:automatic] synonym: "organ mucosa of oral region" EXACT [OBOL:automatic] synonym: "organ mucosa of subdivision of mouth" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucosa" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucosa of organ" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucous membrane" EXACT [OBOL:automatic] synonym: "subdivision of mouth organ mucosa" EXACT [OBOL:automatic] xref: EMAPA:26937 ! mucosa of oral region intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000166 ! oral opening xref: SCTID:362083000 ! Entire oral mucous membrane [Term] id: UBERON:0000355 name: pharyngeal mucosa alt_id: UBERON:0003344 def: "A mucosa that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "Mucous membrane of pharynx" EXACT [FMA:55031] synonym: "mucosa of organ of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of pharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of pharynx" EXACT [OBOL:automatic] synonym: "pharynx mucosa" EXACT [OBOL:automatic] synonym: "pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "mucous membrane of the pharynx" RELATED [BTO:0001047] xref: BTO:0001047 xref: FMA:55031 ! Mucosa of pharynx xref: EMAPA:26957 ! mucosa of pharynx of foregut xref: EMAPA:26965 ! mucosa of pharynx of gut is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001042 ! chordate pharynx synonym: "tunica mucosa pharyngea" EXACT LATIN [FMA:TA, FMA:55031] synonym: "tunica mucosa pharyngis" EXACT [] xref: SCTID:362121003 ! Entire pharyngeal mucous membrane [Term] id: UBERON:0003346 name: mucosa of rectum def: "A mucosa that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of rectum" EXACT [OBOL:automatic] synonym: "mucous membrane of rectum" EXACT [OBOL:automatic] synonym: "organ mucosa of rectum" EXACT [OBOL:automatic] synonym: "rectum mucosa" EXACT [OBOL:automatic] synonym: "rectum mucosa of organ" EXACT [OBOL:automatic] synonym: "rectum mucous membrane" EXACT [OBOL:automatic] synonym: "rectum organ mucosa" EXACT [OBOL:automatic] synonym: "rectal mucosa" EXACT [FMA:15033] synonym: "rectal mucous membrane" EXACT [FMA:15033] xref: EMAPA:27081 ! mucosa of rectum of hindgut xref: EMAPA:27319 ! mucosa of rectum of gut xref: FMA:15033 ! Mucosa of rectum intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001052 ! rectum xref: SCTID:362167003 ! Entire rectal mucous membrane [Term] id: UBERON:0000317 name: colonic mucosa alt_id: UBERON:0004981 alt_id: UBERON:0003347 def: "A mucosa that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of colon" EXACT [FMA:14984] synonym: "colon mucosa" EXACT [FMA:14984] synonym: "colonic mucosa" EXACT [] synonym: "colonic mucous membrane" EXACT [FMA:14984] synonym: "colon mucosa of organ" EXACT [OBOL:automatic] synonym: "colon mucous membrane" EXACT [OBOL:automatic] synonym: "colon organ mucosa" EXACT [OBOL:automatic] synonym: "large bowel mucosa" EXACT [OBOL:automatic] synonym: "large bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "large bowel mucous membrane" EXACT [OBOL:automatic] synonym: "large bowel organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of large bowel" EXACT [OBOL:automatic] synonym: "mucosa of organ of colon" EXACT [OBOL:automatic] synonym: "mucosa of organ of large bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of colon" EXACT [OBOL:automatic] synonym: "mucous membrane of large bowel" EXACT [OBOL:automatic] synonym: "organ mucosa of colon" EXACT [OBOL:automatic] synonym: "organ mucosa of large bowel" EXACT [OBOL:automatic] synonym: "mucosa of segment of colon" EXACT [FMA:85388] xref: BTO:0000271 xref: FMA:14984 ! Mucosa of colon xref: FMA:85388 ! Mucosa of segment of colon xref: EMAPA:27375 ! mucosa of colon xref: EFO:0003038 ! colon mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001155 ! colon xref: SCTID:362157008 ! Entire colonic mucous membrane [Term] id: UBERON:0013067 name: colorectal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0012652 ! colorectum [Term] id: UBERON:0003350 name: epithelium of mucosa def: "A layer of epithelial cells on the surface of the mucosa." [BTO:0003752] synonym: "lamina epithelialis mucosa" RELATED [BTO:0003752] synonym: "lamina epithelialis mucosae" RELATED [BTO:0003752] xref: BTO:0003752 ! lamina epithelialis mucosa xref: EMAPA:18668 ! epithelium of mucosa of jejunum of midgut xref: EMAPA:18835 ! epithelium of mucosa of anal canal xref: EMAPA:18857 ! epithelium of mucosa of gastro-oesophageal junction of gut xref: EMAPA:18862 ! epithelium of mucosa of oesophagus of gut xref: EMAPA:18868 ! epithelium of mucosa of pharynx of gut xref: EMAPA:18893 ! epithelium of mucosa of fundus of stomach of gut xref: EMAPA:18899 ! epithelium of mucosa of glandular region of stomach of gut xref: EMAPA:18912 ! epithelium of mucosa of proventricular region of stomach of gut xref: EMAPA:18917 ! epithelium of mucosa of pyloric region of stomach of gut xref: EMAPA:18927 ! epithelium of mucosa of rectum of gut xref: EMAPA:18934 ! epithelium of mucosa of jejunum of gut xref: EMAPA:18941 ! epithelium of mucosa of colon xref: EMAPA:19078 ! epithelium of mucosa of duodenum of gut xref: EMAPA:26961 ! epithelium of mucosa of pharynx of foregut xref: EMAPA:26985 ! epithelium of mucosa of oesophagus of foregut xref: EMAPA:27019 ! epithelium of mucosa of foregut-midgut junction xref: EMAPA:27033 ! epithelium of mucosa of rostral part of duodenum of foregut xref: EMAPA:27047 ! epithelium of mucosa of gastro-oesophageal junction of foregut xref: EMAPA:27061 ! epithelium of mucosa of perineal body of hindgut xref: EMAPA:27075 ! epithelium of mucosa of rest of hindgut xref: EMAPA:27089 ! epithelium of mucosa of rectum of hindgut xref: EMAPA:27103 ! epithelium of mucosa of caudal part of duodenum of midgut xref: EMAPA:27131 ! epithelium of mucosa of loop xref: EMAPA:27145 ! epithelium of mucosa of rest of midgut xref: EMAPA:27159 ! epithelium of mucosa of fundus of stomach of foregut xref: EMAPA:27175 ! epithelium of mucosa of glandular region of stomach of foregut xref: EMAPA:27191 ! epithelium of mucosa of proventricular region of stomach of foregut xref: EMAPA:27207 ! epithelium of mucosa of pyloric region of stomach of foregut xref: EMAPA:27219 ! epithelium of mucosa of caudal part of anal canal xref: EMAPA:27229 ! epithelium of mucosa of rostral part of anal canal xref: EMAPA:27307 ! epithelium of mucosa of perineal body of gut intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000344 ! mucosa [Term] id: UBERON:0011148 ! submucosal gland name: submucosal gland def: "Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue." [BTO:0003751, Wikipedia:Submucosal_glands] intersection_of: UBERON:0000414 ! mucous gland intersection_of: adjacent_to UBERON:0003350 {notes="perforates"} ! epithelium of mucosa intersection_of: part_of UBERON:0000009 ! submucosa xref: BTO:0003751 ! submucosal gland [Term] id: UBERON:0003352 name: epithelium of midgut synonym: "epithelial tissue of midgut" EXACT [OBOL:automatic] synonym: "midgut epithelial tissue" EXACT [OBOL:automatic] synonym: "midgut epithelium" EXACT [OBOL:automatic] synonym: "midgut epithelium" EXACT [BTO:0005053] relationship: part_of UBERON:0001045 {source="BTO"} ! midgut xref: BTO:0005053 ! midgut epithelium xref: EMAPA:16569 ! epithelium of midgut xref: EHDAA2:0001195 ! midgut epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001045 ! midgut def: "An epithelium that is part of a midgut." [OBOL:automatic] [Term] id: UBERON:0003353 name: epithelium of hindgut def: "An epithelium that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of hindgut" EXACT [OBOL:automatic] synonym: "hindgut epithelial tissue" EXACT [OBOL:automatic] synonym: "hindgut epithelium" EXACT [OBOL:automatic] xref: EMAPA:16717 ! epithelium of hindgut xref: EHDAA2:0000782 ! hindgut epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001046 ! hindgut [Term] id: UBERON:0003354 name: epithelium of rectum def: "An epithelium that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of rectum" EXACT [OBOL:automatic] synonym: "rectum epithelial tissue" EXACT [OBOL:automatic] synonym: "rectum epithelium" EXACT [OBOL:automatic] synonym: "rectal epithelium" EXACT [FMA:17510] xref: EMAPA:17898 ! epithelium of rectum of hindgut xref: FMA:17510 ! Epithelium of rectum xref: VHOG:0001037 ! rectum epithelium xref: EHDAA2:0001594 ! rectum epithelium xref: WBbt:0005800 ! rectal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003355 name: epithelium of incisor def: "An epithelium that is part of a incisor tooth [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of incisor" EXACT [OBOL:automatic] synonym: "epithelial tissue of incisor tooth" EXACT [OBOL:automatic] synonym: "epithelium of incisor tooth" EXACT [OBOL:automatic] synonym: "incisor epithelial tissue" EXACT [OBOL:automatic] synonym: "incisor epithelium" EXACT [OBOL:automatic] synonym: "incisor tooth epithelial tissue" EXACT [OBOL:automatic] synonym: "incisor tooth epithelium" EXACT [OBOL:automatic] xref: EMAPA:17919 ! epithelium of incisor of tooth of lower jaw (also: UBERON:0005710 'lower jaw incisor epithelium') xref: EMAPA:17940 ! epithelium of incisor of tooth of upper jaw (also: UBERON:0005709 'upper jaw incisor epithelium') intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001098 ! incisor tooth [Term] id: UBERON:0003356 name: epithelium of nasal septum def: "An epithelium that is part of a nasal septum [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of nasal septum" EXACT [OBOL:automatic] synonym: "nasal septum epithelial tissue" EXACT [OBOL:automatic] synonym: "nasal septum epithelium" EXACT [OBOL:automatic] xref: EMAPA:18442 ! epithelium of nasal septum intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001706 ! nasal septum [Term] id: UBERON:0003357 name: epithelium of tongue def: "An epithelium that is part of a tongue [Automatically generated definition]." [OBOL:automatic] comment: examples: tongue squamous epithelium, keratined, non-keratinized and parakeratinized epithelium, as well as gustatory epithelium. Note that not all these subtypes are named in individual anatomy ontologies. synonym: "epithelial tissue of tongue" EXACT [OBOL:automatic] synonym: "tongue epithelial tissue" EXACT [OBOL:automatic] synonym: "tongue epithelium" EXACT [OBOL:automatic] synonym: "lingual epithelium" RELATED [BTO:0000992] xref: EMAPA:17881 ! epithelium of tongue of pharynx of foregut xref: EMAPA:18872 ! epithelium of tongue of pharynx of gut xref: BTO:0000992 ! tongue epithelium xref: ncithesaurus:Tongue_Epithelium ! Tongue Epithelium xref: MA:0001592 ! tongue epithelium xref: EHDAA2:0004598 ! tongue epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001723 ! tongue xref: UMLS:C1710436 [Term] id: UBERON:0006919 ! tongue squamous epithelium name: tongue squamous epithelium comment: note this is a singleton subclass of tongue epithelium in MA synonym: "squamous epithelium of tongue" EXACT [OBOL:automatic] xref: MA:0002786 ! tongue squamous epithelium intersection_of: UBERON:0006914 ! squamous epithelium intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0005020 ! mucosa of tongue def: "A squamous epithelium that is part of a tongue." [OBOL:automatic] [Term] id: UBERON:0006916 name: non-keratinized epithelium of tongue xref: FMA:62130 ! non-keratinized epithelium of tongue intersection_of: UBERON:0010304 ! non-keratinized stratified squamous epithelium intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0004650 name: tongue keratinized epithelium synonym: "keratinized epithelium of tongue" EXACT [FMA:74865] xref: FMA:74865 ! Keratinized epithelium of tongue xref: MA:0002787 ! tongue keratinized epithelium intersection_of: UBERON:0012329 ! keratinized stratified squamous epithelium intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0013193 ! parakeratinized epithelium name: parakeratinized epithelium def: "An epithelium that is characterized by incomplete keratinization of the cells in the stratum corneum. The cells are flattened and composed primarily of packed tonofilaments. However, the cells may retain remnants of nuclei and other organelles" [http://www.dental.pitt.edu/informatics/periohistology/en/glossary.html] comment: found in oral epithelium is_a: UBERON:0000488 ! atypical epithelium [Term] id: UBERON:0013194 name: orthokeratinized epithelium def: "A keratinized epithelium in which the cells of the stratum corneum become very flat, loose their nuclei and cytoplasmic organelles and are now composed of densely packed tonofilaments cemented by filaggrin" [http://www.dental.pitt.edu/informatics/periohistology/en/glossary.html] is_a: UBERON:0000488 ! atypical epithelium [Term] id: UBERON:0006918 name: parakeratinized epithelium of tongue synonym: "tongue parakeratinized epithelium" EXACT [] xref: FMA:74908 ! parakeratinized epithelium of tongue intersection_of: UBERON:0013193 ! parakeratinized epithelium intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0013195 name: parakeratinized epithelium of gingiva synonym: "gingival parakeratinized epithelium" EXACT [] intersection_of: UBERON:0013193 ! parakeratinized epithelium intersection_of: part_of UBERON:0001828 ! gingiva [Term] id: UBERON:0006932 name: vestibular epithelium synonym: "epithelium of vestibular labyrinth" EXACT [OBOL:automatic] synonym: "vestibular sensory epithelium" EXACT [FMA:75606] synonym: "inner ear vestibular component epithelium" EXACT [RETIRED_EHDAA2:0000834] xref: MA:0002892 ! vestibular epithelium xref: FMA:75606 ! vestibular sensory epithelium xref: RETIRED_EHDAA2:0000834 ! inner ear vestibular component epithelium is_a: UBERON:0006934 ! sensory epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001862 ! vestibular labyrinth def: "An epithelium that is part of a vestibular labyrinth." [OBOL:automatic] [Term] id: UBERON:0003358 name: epithelium of soft palate def: "An epithelium that is part of a soft palate [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of soft palate" EXACT [OBOL:automatic] synonym: "soft palate epithelial tissue" EXACT [OBOL:automatic] synonym: "soft palate epithelium" EXACT [OBOL:automatic] xref: EMAPA:18950 ! epithelium of soft palate intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001733 ! soft palate [Term] id: UBERON:0003359 name: epithelium of submandibular gland def: "An epithelium that is part of a submandibular gland [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of submandibular gland" EXACT [OBOL:automatic] synonym: "submandibular gland epithelial tissue" EXACT [OBOL:automatic] synonym: "submandibular gland epithelium" EXACT [OBOL:automatic] synonym: "submandibular gland duct epithelium" RELATED [BTO:0004557] xref: EMAPA:18813 ! epithelium of submandibular gland xref: VHOG:0000989 ! submandibular gland epithelium xref: BTO:0004557 ! submandibular gland duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001736 ! submandibular gland [Term] id: UBERON:0006957 name: submandibular gland primordium epithelium xref: EHDAA2:0001940 ! submandibular gland primordium epithelium xref: EMAPA:17756 ! epithelium of submandibular gland primordium (also: UBERON:0004809 'salivary gland epithelium') xref: EHDAA:9257 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006298 ! submandibular gland primordium def: "An epithelium that is part of a submandibular gland primordium." [OBOL:automatic] [Term] id: UBERON:0003360 name: epithelium of parotid gland def: "An epithelium that is part of a parotid gland [Automatically generated definition]." [OBOL:automatic] synonym: "epithelium of parotid" EXACT [OBOL:automatic] synonym: "epithelial tissue of parotid gland" EXACT [OBOL:automatic] synonym: "epithelium of parotid gland" EXACT [OBOL:automatic] synonym: "parotid epithelial tissue" EXACT [OBOL:automatic] synonym: "parotid epithelium" EXACT [OBOL:automatic] synonym: "parotid gland epithelial tissue" EXACT [OBOL:automatic] synonym: "parotid gland epithelium" EXACT [OBOL:automatic] synonym: "parotid gland duct epithelium" RELATED [BTO:0004555] xref: EMAPA:18538 ! epithelium of parotid xref: VHOG:0001434 ! parotid gland epithelium xref: BTO:0004555 ! parotid gland duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001831 ! parotid gland [Term] id: UBERON:0003361 name: epithelium of sublingual gland def: "An epithelium that is part of a sublingual gland [Automatically generated definition]." [OBOL:automatic] synonym: "Rivinus'gland epithelial tissue" EXACT [OBOL:automatic] synonym: "Rivinus'gland epithelium" EXACT [OBOL:automatic] synonym: "ductus sublingualis epithelial tissue" EXACT [OBOL:automatic] synonym: "ductus sublingualis epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of Rivinus'gland" EXACT [OBOL:automatic] synonym: "epithelial tissue of ductus sublingualis" EXACT [OBOL:automatic] synonym: "epithelial tissue of sublingual gland" EXACT [OBOL:automatic] synonym: "epithelium of Rivinus'gland" EXACT [OBOL:automatic] synonym: "epithelium of ductus sublingualis" EXACT [OBOL:automatic] synonym: "sublingual gland epithelial tissue" EXACT [OBOL:automatic] synonym: "sublingual gland epithelium" EXACT [OBOL:automatic] synonym: "sublingual gland duct epithelium" RELATED [BTO:0004559] xref: EMAPA:18810 ! epithelium of sublingual gland xref: VHOG:0001098 ! sublingual gland epithelium xref: BTO:0004559 ! sublingual gland duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001832 ! sublingual gland [Term] id: UBERON:0003362 name: epithelium of endolymphatic duct def: "An epithelium that is part of a endolymphatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "endolymphatic duct epithelial tissue" EXACT [OBOL:automatic] synonym: "endolymphatic duct epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of endolymphatic duct" EXACT [OBOL:automatic] xref: EMAPA:18582 ! epithelium of endolymphatic duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001860 ! endolymphatic duct [Term] id: UBERON:0003363 name: epithelium of ductus reuniens def: "An epithelium that is part of a ductus reuniens [Automatically generated definition]." [OBOL:automatic] synonym: "ductus reuniens epithelial tissue" EXACT [OBOL:automatic] synonym: "ductus reuniens epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of ductus reuniens" EXACT [OBOL:automatic] xref: EMAPA:17289 ! epithelium of ductus reuniens intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001861 ! ductus reuniens [Term] id: UBERON:0003364 name: epithelium of right lung def: "An epithelium that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of right lung" EXACT [OBOL:automatic] synonym: "right lung epithelial tissue" EXACT [OBOL:automatic] synonym: "right lung epithelium" EXACT [OBOL:automatic] xref: EMAPA:17663 ! epithelium of right lung intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0003365 name: epithelium of left lung def: "An epithelium that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of left lung" EXACT [OBOL:automatic] synonym: "left lung epithelial tissue" EXACT [OBOL:automatic] synonym: "left lung epithelium" EXACT [OBOL:automatic] xref: EMAPA:17655 ! epithelium of left lung intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002168 ! left lung [Term] id: UBERON:0003366 name: epithelium of uterine horn def: "An epithelium that is part of a uterine horn [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of uterine horn" EXACT [OBOL:automatic] synonym: "uterine horn epithelial tissue" EXACT [OBOL:automatic] synonym: "uterine horn epithelium" EXACT [OBOL:automatic] xref: EMAPA:29030 ! epithelium of uterine horn intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002247 ! uterine horn [Term] id: UBERON:0003368 name: epithelium of hard palate def: "An epithelium that is part of a hard palate [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of hard palate" EXACT [OBOL:automatic] synonym: "hard palate epithelial tissue" EXACT [OBOL:automatic] synonym: "hard palate epithelium" EXACT [OBOL:automatic] xref: EMAPA:18953 ! epithelium of hard palate intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003216 ! hard palate [Term] id: UBERON:0003373 name: ectoderm of footplate xref: EMAPA:17250 ! ectoderm of footplate intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0006871 ! footplate def: "An ectoderm that is part of a footplate." [OBOL:automatic] [Term] id: UBERON:0003379 name: cardiac muscle of right atrium def: "A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle of cardiac right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of heart right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of right atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of right atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of right atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of right cardiac atrium" EXACT [OBOL:automatic] synonym: "right atrium myocardium" EXACT [VHOG:0001227] synonym: "myocardium of right atrium" EXACT [] synonym: "right atrium heart muscle" EXACT [EHDAA2:0004155] xref: EMAPA:17326 ! cardiac muscle of right atrium xref: FMA:7282 ! Cardiac muscle tissue of right atrium xref: VHOG:0001227 ! right atrium myocardium xref: SCTID:362018002 ! Entire myocardium of right atrium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002078 ! right atrium xref: EHDAA2:0004155 ! right atrium heart muscle [Term] id: UBERON:0003380 name: cardiac muscle of left atrium def: "A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac left atrium cardiac muscle" EXACT [OBOL:automatic] synonym: "cardiac left atrium cardiac muscle tissue" EXACT [OBOL:automatic] synonym: "cardiac muscle of cardiac left atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart left atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of left atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of cardiac left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of heart left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left cardiac atrium" EXACT [OBOL:automatic] synonym: "left atrium myocardium" EXACT [VHOG:0001225] synonym: "left atrium heart muscle" EXACT [EHDAA2:0004154] synonym: "myocardium of left atrium" EXACT [] xref: EMAPA:17320 ! cardiac muscle of left atrium xref: FMA:7285 ! Cardiac muscle tissue of left atrium xref: VHOG:0001225 ! left atrium myocardium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002079 ! left atrium xref: EHDAA2:0004154 ! left atrium heart muscle xref: SCTID:189936008 ! Entire myocardium of left atrium [Term] id: UBERON:0003381 ! cardiac muscle of right ventricle name: cardiac muscle of right ventricle def: "A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "right ventricular cardiac muscle tissue" EXACT [GO:0003221] xref: EMAPA:17342 ! cardiac muscle of right ventricle xref: FMA:83452 ! Cardiac muscle tissue of right ventricle xref: VHOG:0001236 ! right ventricle myocardium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002080 ! right ventricle synonym: "cardiac muscle tissue of right ventricle" EXACT [FMA:83452] synonym: "right ventricle cardiac muscle" RELATED [VHOG:0001236] [Term] id: UBERON:0003382 name: cardiac muscle of left ventricle def: "A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "left ventricular cardiac muscle tissue" EXACT [GO:0003220] xref: EMAPA:17339 ! cardiac muscle of left ventricle xref: FMA:83453 ! Cardiac muscle tissue of left ventricle xref: VHOG:0001234 ! left ventricle myocardium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002084 ! left ventricle synonym: "cardiac muscle tissue of left ventricle" EXACT [FMA:83453] synonym: "left ventricle cardiac muscle" RELATED [VHOG:0001234] [Term] id: UBERON:0003383 name: cardiac muscle of interventricular septum def: "A portion of cardiac muscle tissue that is part of a interventricular septum [Automatically generated definition]." [OBOL:automatic] synonym: "interventricular septum cardiac muscle" EXACT [VHOG:0000999] synonym: "interventricular septum heart muscle" EXACT [EHDAA2:0004158] xref: EMAPA:17335 ! cardiac muscle of interventricular septum xref: FMA:84084 ! Cardiac muscle tissue of interventricular septum xref: VHOG:0000999 ! interventricular septum cardiac muscle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002094 ! interventricular septum xref: EHDAA2:0004158 ! interventricular septum heart muscle synonym: "cardiac muscle tissue of interventricular septum" EXACT [FMA:84084] synonym: "interventricular septum myocardium" EXACT [VHOG:0000999] [Term] id: UBERON:0003384 name: skeletal muscle of pharynx def: "A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "pharynx skeletal muscle" EXACT [OBOL:automatic] synonym: "pharynx skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of pharynx" EXACT [OBOL:automatic] xref: EMAPA:18963 ! skeletal muscle of pharynx of gut intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001042 ! chordate pharynx [Term] id: UBERON:0003385 name: skeletal muscle of mesenchyme def: "A portion of skeletal muscle tissue that is part of a mesenchyme [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme skeletal muscle" EXACT [OBOL:automatic] synonym: "mesenchyme skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:19066 ! skeletal muscle of mesenchyme of upper arm xref: EMAPA:19071 ! skeletal muscle of mesenchyme of upper leg intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0003104 ! mesenchyme [Term] id: UBERON:0003387 name: smooth muscle of trachea alt_id: UBERON:0004244 def: "A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]." [OBOL:automatic] synonym: "trachea smooth muscle" EXACT [MA:0001863] synonym: "tracheal smooth muscle" EXACT [BTO:0001391] xref: MA:0001863 ! trachea smooth muscle xref: EMAPA:19192 ! smooth muscle of trachea xref: FMA:262010 ! Smooth muscle of trachea xref: BTO:0001391 ! tracheal smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003126 ! trachea xref: ncithesaurus:Trachea_Smooth_Muscle_Tissue ! Trachea Smooth Muscle Tissue xref: UMLS:C1710458 [Term] id: UBERON:0001136 name: mesothelium def: "Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri)." [Wikipedia:Mesothelium, FMA:14074] comment: This class was created automatically from a combination of ontologies subset: uberon_slim xref: EHDAA:2331 ! mesothelium xref: EHDAA:2349 ! mesothelium xref: EHDAA:295 ! mesothelium xref: EHDAA:6073 ! mesothelium xref: EHDAA:640 ! mesothelium xref: EHDAA:646 ! mesothelium xref: FMA:14074 ! Mesothelium xref: MA:0000565 ! mesothelium xref: ncithesaurus:Mesothelium ! Mesothelium xref: BTO:0002422 ! mesothelium xref: EHDAA2_RETIRED:0003111 ! mesothelium xref: AEO:0000111 ! mesothelium intersection_of: UBERON:0000487 ! simple squamous epithelium intersection_of: develops_from UBERON:0000926 ! mesoderm intersection_of: part_of UBERON:0000042 ! serous membrane relationship: develops_from UBERON:0000926 {source="FMA-inferred"} ! mesoderm relationship: composed_primarily_of CL:0000077 {source="FMA"} ! mesothelial cell xref: SCTID:361918002 ! Entire mesothelium xref: http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg xref: UMLS:C0086610 [Term] id: UBERON:0007140 ! parietal mesothelium name: parietal mesothelium def: "Mesothelium overs the body walls is called the parietal mesothelium" [http://en.wikipedia.org/wiki/Mesothelium] xref: MA:0000566 ! parietal mesothelium is_a: UBERON:0001136 ! mesothelium [Term] id: UBERON:0007141 ! visceral mesothelium name: visceral mesothelium def: "Mesothelium that covers the internal organs is called visceral mesothelium" [http://en.wikipedia.org/wiki/Mesothelium] xref: MA:0000567 ! visceral mesothelium is_a: UBERON:0001136 ! mesothelium [Term] id: UBERON:0007188 name: mesothelium of serous pericardium synonym: "mesothelium of pericardium" EXACT [FMA:18149] synonym: "pericardial mesothelium" EXACT [FMA:18149] synonym: "serous pericardium mesothelium" EXACT [FMA:18149] xref: FMA:18149 ! mesothelium of serous pericardium xref: EMAPA:16133 ! mesothelium of pericardial component xref: BTO:0003157 ! pericardial mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0002357 ! serous pericardium xref: SCTID:67300002 ! Pericardial mesothelium def: "A mesothelium that is part of a serous pericardium." [OBOL:automatic] [Term] id: UBERON:0007185 name: pericardio-peritoneal canal mesothelium xref: EMAPA:16284 ! mesothelium of pericardio-peritoneal canal xref: VHOG:0000447 ! pericardio-peritoneal canal mesothelium xref: EHDAA2:0001442 ! pericardio-peritoneal canal mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0006275 ! pericardio-peritoneal canal synonym: "pericardio-peritoneal canal mehomhelium" RELATED [VHOG:0000447] def: "A mesothelium that is part of a pericardio-peritoneal canal." [OBOL:automatic] [Term] id: UBERON:0007186 name: pericardial visceral mesothelium xref: VHOG:0000778 ! pericardial visceral mesothelium xref: EMAPA:16589 ! visceral mesothelium of pericardial component xref: FMA:19741 ! Mesothelium of visceral serous pericardium intersection_of: UBERON:0007141 ! visceral mesothelium intersection_of: part_of UBERON:0002407 ! pericardium synonym: "mesothelium of visceral serous pericardium" EXACT [FMA:19741] synonym: "mesothelium of visceral pericardium" EXACT [FMA:19741] synonym: "visceral serous pericardium mesothelium" EXACT [FMA:19741] synonym: "pericardial visceral mehomhelium" RELATED [VHOG:0000778] property_value: homology_notes "Found in all vertebrates, the VP (visceral pericardium) is also known as the cardiac epimysium. This outermost layer of the epicardium consists of a thin layer of mesothelial cells over a dense network of collagen and elastin fibers.[well established][VHOG]" xsd:string {external_class="VHOG:0000778", ontology="VHOG", source="DOI:10.1152/ajpheart.00967.2007 Jöbsis PD\, Ashikaga H\, Wen H\, Rothstein EC\, Horvath KA\, McVeigh ER\, Balaban RS\, The visceral pericardium: macromolecular structure and contribution to passive mechanical properties of the left ventricle. American journal of physiology\, Heart and circulatory physiology (2007)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A visceral mesothelium that is part of a pericardium." [OBOL:automatic] [Term] id: UBERON:0007187 name: pericardial parietal mesothelium xref: EMAPA:16588 ! parietal mesothelium of pericardial component xref: FMA:19742 ! Mesothelium of parietal serous pericardium intersection_of: UBERON:0007140 ! parietal mesothelium intersection_of: part_of UBERON:0002407 ! pericardium synonym: "mesothelium of parietal serous pericardium" EXACT [FMA:19742] synonym: "mesothelium of parietal pericardium" EXACT [FMA:19742] synonym: "parietal serous pericardium mesothelium" EXACT [FMA:19742] def: "A parietal mesothelium that is part of a pericardium." [OBOL:automatic] [Term] id: UBERON:0003274 name: mesothelium of omental bursa def: "A mesothelium that is part of a lesser sac [Automatically generated definition]." [OBOL:automatic] synonym: "omental bursa mesothelium" EXACT [OBOL:automatic] synonym: "omental bursa mehomhelium" RELATED [VHOG:0000441] synonym: "lesser sac mesothelium" EXACT [EHDAA2:0004557] xref: EHDAA:2339 ! mesothelium xref: VHOG:0000441 ! omental bursa mesothelium xref: RETIRED_EHDAA2:0001299 ! omental bursa mesothelium xref: EMAPA:16890 ! mesothelium of omental bursa of peritoneal component xref: EMAPA:18459 ! mesothelium of omental bursa of peritoneal cavity intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0001341 ! lesser sac xref: EHDAA2:0004557 ! lesser sac mesothelium [Term] id: UBERON:0003388 name: mesothelium of pericardial cavity def: "A mesothelium that is part of a pericardial cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of pericardial sac meso-epithelium" EXACT [OBOL:automatic] synonym: "cavity of pericardial sac mesothelium" EXACT [OBOL:automatic] synonym: "meso-epithelium of cavity of pericardial sac" EXACT [OBOL:automatic] synonym: "meso-epithelium of pericardial cavity" EXACT [OBOL:automatic] synonym: "mesothelium of cavity of pericardial sac" EXACT [OBOL:automatic] synonym: "pericardial cavity meso-epithelium" EXACT [OBOL:automatic] synonym: "pericardial cavity mesothelium" EXACT [OBOL:automatic] xref: EMAPA:18449 ! mesothelium of pericardial cavity xref: RETIRED_EHDAA2:0001436 ! pericardial cavity mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: located_in UBERON:0001074 ! pericardial cavity [Term] id: UBERON:0003389 name: mesothelium of diaphragm def: "A mesothelium that is part of a diaphragm [Automatically generated definition]." [OBOL:automatic] synonym: "diaphragm meso-epithelium" EXACT [OBOL:automatic] synonym: "diaphragm mesothelium" EXACT [OBOL:automatic] synonym: "meso-epithelium of diaphragm" EXACT [OBOL:automatic] synonym: "meso-epithelium of thoracic diaphragm" EXACT [OBOL:automatic] synonym: "mesothelium of thoracic diaphragm" EXACT [OBOL:automatic] synonym: "thoracic diaphragm meso-epithelium" EXACT [OBOL:automatic] synonym: "thoracic diaphragm mesothelium" EXACT [OBOL:automatic] xref: EMAPA:18429 ! mesothelium of diaphragm intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0001103 ! diaphragm [Term] id: UBERON:0003390 name: mesothelium of pleural cavity def: "A mesothelium that is part of a pleural cavity [Automatically generated definition]." [OBOL:automatic] synonym: "meso-epithelium of pleural cavity" EXACT [OBOL:automatic] synonym: "pleural cavity meso-epithelium" EXACT [OBOL:automatic] synonym: "pleural cavity mesothelium" EXACT [OBOL:automatic] xref: EMAPA:18463 ! mesothelium of pleural cavity xref: EHDAA2:0001476 ! pleural cavity mesothelium xref: BTO:0003155 ! pleural mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: located_in UBERON:0002402 ! pleural cavity [Term] id: UBERON:0003393 name: mesentery of urinary system def: "A mesentery that is part of a urinary system [Automatically generated definition]." [OBOL:automatic] synonym: "excretory system mesentery" EXACT [OBOL:automatic] synonym: "mesentery of excretory system" EXACT [OBOL:automatic] synonym: "mesentery of renal system" EXACT [OBOL:automatic] synonym: "mesentery of systema urinaria" EXACT [OBOL:automatic] synonym: "renal system mesentery" EXACT [OBOL:automatic] synonym: "systema urinaria mesentery" EXACT [OBOL:automatic] synonym: "urinary system mesentery" EXACT [OBOL:automatic] xref: EMAPA:17367 ! mesentery of urinary system intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001008 ! urinary system [Term] id: UBERON:0003394 name: mesentery of hindgut def: "A mesentery that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "hindgut mesentery" EXACT [OBOL:automatic] xref: EMAPA:16718 ! mesentery of hindgut intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001046 ! hindgut [Term] id: UBERON:0003395 name: mesentery of rectum def: "A mesentery that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "rectum mesentery" EXACT [OBOL:automatic] xref: EMAPA:18664 ! mesentery of rectum of hindgut xref: EMAPA:18929 ! mesentery of rectum of gut intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003396 name: mesentery of colon def: "A mesentery that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon mesentery" EXACT [OBOL:automatic] synonym: "large bowel mesentery" EXACT [OBOL:automatic] synonym: "mesentery of large bowel" EXACT [OBOL:automatic] synonym: "mesentery of large intestine" EXACT [FMA:14645] synonym: "large intestinal mesentery" EXACT [FMA:14645] xref: EMAPA:18942 ! mesentery of colon xref: FMA:14645 ! Mesentery of large intestine is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001155 ! colon xref: SCTID:245457004 ! Large intestine mesentery [Term] id: UBERON:0003397 name: mesentery of duodenum def: "A mesentery that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "duodenum mesentery" EXACT [OBOL:automatic] xref: EMAPA:19081 ! mesentery of duodenum of gut intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0002114 ! duodenum [Term] id: UBERON:0003398 name: mesentery of jejunum def: "A mesentery that is part of a jejunum [Automatically generated definition]." [OBOL:automatic] synonym: "jejunal mesentery" EXACT [] synonym: "jejunum mesentery" EXACT [] synonym: "mesojejunum" EXACT [http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html] xref: EMAPA:18670 ! mesentery of jejunum of midgut xref: EMAPA:18937 ! mesentery of jejunum of gut xref: FMA:14651 ! Mesentery of jejunum intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0002115 ! jejunum xref: SCTID:261286003 ! Entire jejunal mesentery [Term] id: UBERON:0001517 name: skin of elbow alt_id: UBERON:0003399 def: "A zone of skin that is part of a elbow [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "elbow skin" EXACT [] synonym: "cubital region zone of skin" EXACT [OBOL:automatic] synonym: "elbow zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of cubital region" EXACT [OBOL:automatic] synonym: "zone of skin of elbow" EXACT [OBOL:automatic] xref: FMA:38250 ! Skin of elbow xref: MA:0000610 ! elbow skin xref: EMAPA:18051 ! skin of elbow xref: ncithesaurus:Elbow_Skin ! Elbow Skin is_a: UBERON:0002427 ! arm skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001461 ! elbow relationship: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001461 ! elbow xref: SCTID:181534001 ! Entire skin of elbow xref: UMLS:C0222213 [Term] id: UBERON:0003403 name: skin of forearm def: "A zone of skin that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "antebrachial region skin" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb skin" EXACT [OBOL:automatic] synonym: "lower arm skin" EXACT [OBOL:automatic] synonym: "lower segment of arm skin" EXACT [OBOL:automatic] synonym: "skin of antebrachial region" EXACT [OBOL:automatic] synonym: "skin of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "skin of lower arm" EXACT [OBOL:automatic] synonym: "skin of lower segment of arm" EXACT [OBOL:automatic] synonym: "skin of zeugopod of arm" EXACT [OBOL:automatic] synonym: "zeugopod of arm skin" EXACT [OBOL:automatic] synonym: "arm middle limb segment skin" EXACT [OBOL:automatic] synonym: "arm zeugopod skin" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment skin" EXACT [OBOL:automatic] synonym: "brachial region zeugopod skin" EXACT [OBOL:automatic] synonym: "middle limb segment of arm skin" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region skin" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb skin" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment skin" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod skin" EXACT [OBOL:automatic] synonym: "skin of arm middle limb segment" EXACT [OBOL:automatic] synonym: "skin of arm zeugopod" EXACT [OBOL:automatic] synonym: "skin of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "skin of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "skin of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "skin of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "skin of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "skin of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "skin of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "skin of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "skin of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region skin" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb skin" EXACT [OBOL:automatic] synonym: "forearm skin" EXACT [FMA:38265] xref: EMAPA:18056 ! skin of forearm xref: FMA:38265 ! Skin of forearm xref: MA:0000602 ! lower arm skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002386 ! forearm xref: SCTID:181537008 ! Entire skin of forearm [Term] id: UBERON:0003406 name: cartilage of respiratory system def: "A cartilage that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius cartilage" EXACT [OBOL:automatic] synonym: "cartilage of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "respiratory system cartilage" EXACT [OBOL:automatic] xref: EMAPA:18694 ! cartilage of respiratory system xref: MA:0001818 ! respiratory system cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0001823 name: nasal cartilage def: "One of the cartilage structures in the nose that provide form and support[WP]." [Wikipedia:Nasal_cartilage] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "cartilage of nose" EXACT [] xref: FMA:59502 ! Nasal cartilage xref: MA:0001883 ! nasal cartilage xref: ncithesaurus:Nasal_Cartilage ! Nasal Cartilage xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e1/Gray852.png/200px-Gray852.png is_a: UBERON:0002418 {source="MA"} ! cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0000004 ! olfactory apparatus relationship: encloses UBERON:0000402 ! nasal vestibule xref: SCTID:278941001 ! Entire nasal cartilage xref: UMLS:C0225415 [Term] id: UBERON:0003407 name: cartilage of nasal septum def: "A cartilage that is part of a nasal septum [Automatically generated definition]." [OBOL:automatic] synonym: "nasal septum cartilage" EXACT [OBOL:automatic] synonym: "septal nasal cartilage" EXACT [FMA:59503] synonym: "cartilago septal nasi" EXACT [FMA:59503] xref: EMAPA:25091 ! cartilage of nasal septum xref: FMA:59503 ! septal nasal cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0001706 ! nasal septum [Term] id: UBERON:0007818 name: major alar cartilage def: "The greater alar cartilage (lower lateral cartilage) is a thin, flexible plate, situated immediately below the preceding, and bent upon itself in such a manner as to form the medial wall and lateral wall of the naris of its own side. The portion which forms the medial wall (crus mediale) is loosely connected with the corresponding portion of the opposite cartilage, the two forming, together with the thickened integument and subjacent tissue, the septum mobile nasi. The part which forms the lateral wall (crus laterale) is curved to correspond with the ala of the nose; it is oval and flattened, narrow behind, where it is connected with the frontal process of the maxilla by a tough fibrous membrane, in which are found three or four small cartilaginous plates, the lesser alar cartilages (cartilagines alares minores; sesamoid cartilages). Above, it is connected by fibrous tissue to the lateral cartilage and front part of the cartilage of the septum; below, it falls short of the margin of the naris, the ala being completed by fatty and fibrous tissue covered by skin. In front, the greater alar cartilages are separated by a notch which corresponds with the apex of the nose." [Wikipedia:Greater_alar_cartilage] synonym: "cartilago alaris major" EXACT [FMA:59504] synonym: "greater alar cartilage" EXACT [FMA:59504] xref: FMA:59504 ! Major alar cartilage is_a: UBERON:0001823 {source="FMA"} ! nasal cartilage xref: SCTID:361928006 ! Entire greater alar cartilage synonym: "cartilago alaris major" RELATED LATIN [Wikipedia:Greater_alar_cartilage] xref: http://upload.wikimedia.org/wikipedia/commons/e/e1/Gray852.png [Term] id: UBERON:0007819 name: minor alar cartilage def: "The part which forms the lateral wall is curved to correspond with the ala of the nose; it is oval and flattened, narrow behind, where it is connected with the frontal process of the maxilla by a tough fibrous membrane, in which are found three or four small cartilaginous plates, the lesser alar cartilages." [Wikipedia:Lesser_alar_cartilages] synonym: "lesser alar cartilage" EXACT [FMA:59507] synonym: "lesser alar cartilages" RELATED PLURAL [] xref: FMA:59507 ! Minor alar cartilage xref: SCTID:368118006 ! Entire lesser alar cartilages is_a: UBERON:0001823 {source="FMA"} ! nasal cartilage synonym: "cartilago alaris minor" RELATED LATIN [Wikipedia:Lesser_alar_cartilages] xref: http://upload.wikimedia.org/wikipedia/commons/e/e1/Gray852.png [Term] id: UBERON:0007820 name: accessory nasal cartilage def: "small cartilages of the nose connecting the greater alar cartilage and lateral nasal cartilage." [Wikipedia:Accessory_nasal_cartilages] xref: FMA:59510 ! Accessory nasal cartilage xref: SCTID:368124000 ! Entire accessory nasal cartilages synonym: "cartilago nasi accessoriae" RELATED LATIN [Wikipedia:Accessory_nasal_cartilage] is_a: UBERON:0001823 {source="FMA"} ! nasal cartilage [Term] id: UBERON:0007821 name: lateral nasal cartilage def: "The lateral cartilage (upper lateral cartilage) is situated below the inferior margin of the nasal bone, and is flattened, and triangular in shape.[WP]." [Wikipedia:Lateral_nasal_cartilage] xref: FMA:59511 ! Lateral nasal cartilage is_a: UBERON:0001823 {source="FMA"} ! nasal cartilage xref: SCTID:278944009 ! Entire lateral nasal cartilage synonym: "cartilago nasi lateralis" RELATED LATIN [Wikipedia:Lateral_nasal_cartilage] xref: http://upload.wikimedia.org/wikipedia/commons/e/e1/Gray852.png [Term] id: UBERON:0003408 name: gland of gut def: "A gland that is part of a digestive tract [Automatically generated definition]." [OBOL:automatic] synonym: "digestive tract gland" EXACT [OBOL:automatic] synonym: "gland of digestive tract" EXACT [OBOL:automatic] synonym: "gland of lower gastrointestinal tract" EXACT [OBOL:automatic] synonym: "gut gland" EXACT [OBOL:automatic] synonym: "lower gastrointestinal tract gland" EXACT [OBOL:automatic] xref: EMAPA:18815 ! gland of gut intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0003409 name: gland of tongue def: "A gland that is part of a tongue [Automatically generated definition]." [OBOL:automatic] synonym: "tongue gland" EXACT [OBOL:automatic] xref: EMAPA:25097 ! gland of tongue of pharynx of gut intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0013475 name: gustatory gland def: "A serous salivary gland which resides adjacent to the moats surrounding the circumvallate papillae in the posterior one-third of the tongue, anterior to the terminal sulcus." [Wikipedia:Von_Ebner's_gland] synonym: "von Ebner's gland" EXACT [Wikipedia:Von_Ebner's_gland] synonym: "von Ebner gland" EXACT [Wikipedia:Von_Ebner's_gland] is_a: UBERON:0000409 ! serous gland is_a: UBERON:0001044 ! salivary gland relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0003295 name: pharyngeal gland def: "Racemose mucous glands beneath the mucous membrane of the pharynx." [Biology-Online_Dictionary:http://www.biology-online.org/dictionary/] synonym: "glandulae pharyngeae" RELATED [BTO:0004849] synonym: "pharynx gland" EXACT [EHDAA2:0001461] xref: BTO:0004849 ! pharyngeal gland xref: EHDAA:2967 ! gland xref: EHDAA2:0001461 ! pharynx gland xref: FMA:55075 ! pharyngeal gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 {source="BTO"} ! chordate pharynx subset: organ_slim [Term] id: UBERON:0008310 name: nasopharyngeal gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001728 ! nasopharynx xref: FMA:55076 ! nasopharyngeal gland xref: SCTID:178973008 ! Entire nasopharyngeal gland subset: organ_slim def: "A gland that is part of a nasopharynx." [OBOL:automatic] [Term] id: UBERON:0003410 name: oropharyngeal gland def: "A gland that is part of a oropharynx [Automatically generated definition]." [OBOL:automatic] synonym: "gland of oral part of pharynx" EXACT [OBOL:automatic] synonym: "oral part of pharynx gland" EXACT [OBOL:automatic] synonym: "oropharynx gland" EXACT [OBOL:automatic] xref: EMAPA:25095 ! gland of oropharynx synonym: "gland of oropharynx" EXACT [EMAPA:25095] intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001729 ! oropharynx subset: organ_slim [Term] id: UBERON:0003414 name: mesenchyme of mandible def: "Mesenchyme that is part of a mandible [Automatically generated definition]." [OBOL:automatic] synonym: "lower jaw bone mesenchyme" EXACT [OBOL:automatic] synonym: "mandible mesenchyme" EXACT [OBOL:automatic] synonym: "mandibulla mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of lower jaw bone" EXACT [OBOL:automatic] synonym: "mesenchyme of mandibulla" EXACT [OBOL:automatic] synonym: "bone of lower jaw mesenchyme" EXACT [OBOL:automatic] synonym: "bone of ventral mandibular arch mesenchyme" EXACT [OBOL:automatic] synonym: "bone organ of lower jaw mesenchyme" EXACT [OBOL:automatic] synonym: "bone organ of ventral mandibular arch mesenchyme" EXACT [OBOL:automatic] synonym: "lower jaw bone organ mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of bone of lower jaw" EXACT [OBOL:automatic] synonym: "mesenchyme of bone of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "mesenchyme of bone organ of lower jaw" EXACT [OBOL:automatic] synonym: "mesenchyme of bone organ of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "mesenchyme of lower jaw bone organ" EXACT [OBOL:automatic] synonym: "mesenchyme of ventral mandibular arch bone" EXACT [OBOL:automatic] synonym: "mesenchyme of ventral mandibular arch bone organ" EXACT [OBOL:automatic] synonym: "ventral mandibular arch bone mesenchyme" EXACT [OBOL:automatic] synonym: "ventral mandibular arch bone organ mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:17912 ! mesenchyme of mandible intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001684 ! mandible [Term] id: UBERON:0003415 name: mesenchyme of nasal septum def: "Mesenchyme that is part of a nasal septum [Automatically generated definition]." [OBOL:automatic] synonym: "nasal septum mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18443 ! mesenchyme of nasal septum intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001706 ! nasal septum [Term] id: UBERON:0003416 name: mesenchyme of tongue def: "Mesenchyme that is part of a tongue [Automatically generated definition]." [OBOL:automatic] comment: todo - develops_from synonym: "tongue mesenchyme" EXACT [EHDAA2:0004614] xref: EMAPA:17882 ! mesenchyme of tongue of pharynx of foregut xref: EMAPA:18878 ! mesenchyme of tongue of pharynx of gut xref: EHDAA2:0004614 ! tongue mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0003417 name: mesenchyme of soft palate def: "Mesenchyme that is part of a soft palate [Automatically generated definition]." [OBOL:automatic] synonym: "soft palate mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18951 ! mesenchyme of soft palate intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001733 ! soft palate [Term] id: UBERON:0003418 name: mesenchyme of submandibular gland def: "Mesenchyme that is part of a submandibular gland [Automatically generated definition]." [OBOL:automatic] synonym: "submandibular gland mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18814 ! mesenchyme of submandibular gland xref: VHOG:0001110 ! submandibular gland mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001736 ! submandibular gland [Term] id: UBERON:0003419 name: mesenchyme of parotid def: "Mesenchyme that is part of a parotid gland [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme of parotid gland" EXACT [OBOL:automatic] synonym: "parotid gland mesenchyme" EXACT [OBOL:automatic] synonym: "parotid mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18539 ! mesenchyme of parotid xref: VHOG:0001435 ! parotid gland mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001831 ! parotid gland [Term] id: UBERON:0003420 name: mesenchyme of sublingual gland def: "Mesenchyme that is part of a sublingual gland [Automatically generated definition]." [OBOL:automatic] synonym: "Rivinus'gland mesenchyme" EXACT [OBOL:automatic] synonym: "ductus sublingualis mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of Rivinus'gland" EXACT [OBOL:automatic] synonym: "mesenchyme of ductus sublingualis" EXACT [OBOL:automatic] synonym: "sublingual gland mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18811 ! mesenchyme of sublingual gland xref: VHOG:0001106 ! sublingual gland mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001832 ! sublingual gland [Term] id: UBERON:0003422 name: mesenchyme of umbilical cord def: "a gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP]" [Wikipedia:Wharton\'s_jelly] comment: todo - check synonym: "Wharton's jelly" EXACT [EMAPA:26127] synonym: "umbilical cord mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:26127 ! mesenchyme of umbilical cord intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: has_part CHEBI:37395 {source="Wikipedia"} ! mucopolysaccharide xref: SCTID:368069009 ! Entire Wharton's jelly [Term] id: UBERON:0003424 name: mesenchyme of hard palate def: "Mesenchyme that is part of a hard palate [Automatically generated definition]." [OBOL:automatic] synonym: "hard palate mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18954 ! mesenchyme of hard palate intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003216 ! hard palate [Term] id: UBERON:0003425 name: renal lymph node def: "A lymph node that is part of a kidney [Automatically generated definition]." [OBOL:automatic] synonym: "kidney lymph node" EXACT [OBOL:automatic] synonym: "lymph node of kidney" EXACT [OBOL:automatic] xref: MA:0002882 ! renal lymph node intersection_of: UBERON:0000029 ! lymph node intersection_of: part_of UBERON:0002113 ! kidney xref: ncithesaurus:Renal_Lymph_Node ! Renal Lymph Node xref: UMLS:C2699031 [Term] id: UBERON:0003426 name: dermis adipose tissue def: "An adipose tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic] synonym: "adipose tissue of dermis" EXACT [OBOL:automatic] synonym: "dermis fat tissue" EXACT [OBOL:automatic] synonym: "dermis fatty tissue" EXACT [OBOL:automatic] synonym: "fat tissue of dermis" EXACT [OBOL:automatic] synonym: "fatty tissue of dermis" EXACT [OBOL:automatic] xref: MA:0000798 ! dermis adipose tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0002067 ! dermis [Term] id: UBERON:0003427 name: abdominal fat pad def: "the encapsulated adipose tissue in the abdomen." [MP:0000010] synonym: "abdomen fat pad" EXACT [OBOL:automatic] synonym: "fat pad of abdomen" EXACT [OBOL:automatic] xref: MA:0000472 ! abdominal fat pad intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0003428 name: gonadal fat pad def: "the encapsulated adipose tissue associated with the ovaries or testes." [MP:0005335] comment: Editor notes: consider change relationship from part_of. AO notes: we place the amphibian structures here as their definitions state a gonadal association. synonym: "fat pad of gonad" EXACT [OBOL:automatic] synonym: "fat pad of gonads" EXACT [OBOL:automatic] synonym: "gonad fat pad" EXACT [OBOL:automatic] synonym: "gonadal fat pad" EXACT [OBOL:automatic] synonym: "gonad-associated fat pad" EXACT [] xref: AAO:0000157 ! fat_bodies xref: XAO:0003050 ! fat body property_value: external_definition "Anatomical structure associated with the gonads which vary in form among amphibians but are primarily composed of adipose tissue and are thought to be a source of nutrients for the gonads.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000157", date_retrieved="2012-06-20", source="AAO:BJB"} xref: MA:0002547 ! gonadal fat pad xref: EFO:0000811 ! fat body sensu amphibia intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0000991 ! gonad [Term] id: UBERON:0003429 name: abdomen nerve def: "A nerve that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of abdomen" EXACT [OBOL:automatic] xref: MA:0000521 ! abdomen nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0003430 name: neck nerve def: "A nerve that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "neck (volume) nerve" EXACT [OBOL:automatic] synonym: "nerve of neck" EXACT [OBOL:automatic] synonym: "nerve of neck (volume)" EXACT [OBOL:automatic] xref: MA:0000588 ! neck nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003431 name: leg nerve def: "A nerve that is part of a leg [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of leg" EXACT [OBOL:automatic] xref: MA:0000673 ! leg nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000978 ! leg [Term] id: UBERON:0003432 name: chest nerve def: "A nerve that is part of a chest [Automatically generated definition]." [OBOL:automatic] synonym: "anterior thoracic region nerve" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax nerve" EXACT [OBOL:automatic] synonym: "front of thorax nerve" EXACT [OBOL:automatic] synonym: "nerve of anterior thoracic region" EXACT [OBOL:automatic] synonym: "nerve of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "nerve of chest" EXACT [OBOL:automatic] synonym: "nerve of front of thorax" EXACT [OBOL:automatic] xref: MA:0000551 ! chest nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001443 ! chest [Term] id: UBERON:0003433 name: arm nerve def: "A nerve that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "brachial region nerve" EXACT [OBOL:automatic] synonym: "nerve of arm" EXACT [OBOL:automatic] synonym: "nerve of brachial region" EXACT [OBOL:automatic] synonym: "nerve of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb nerve" EXACT [OBOL:automatic] xref: MA:0000595 ! arm nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001460 ! arm [Term] id: UBERON:0003434 name: wrist nerve def: "A nerve that is part of a wrist [Automatically generated definition]." [OBOL:automatic] synonym: "carpal region nerve" EXACT [OBOL:automatic] synonym: "nerve of carpal region" EXACT [OBOL:automatic] synonym: "nerve of wrist" EXACT [OBOL:automatic] xref: MA:0000637 ! wrist nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0003435 name: pedal digit nerve def: "A nerve that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit nerve" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit nerve" EXACT [OBOL:accepted] synonym: "digit of foot nerve" EXACT [OBOL:automatic] synonym: "digitus pedis nerve" EXACT [OBOL:automatic] synonym: "nerve of digit of foot" EXACT [OBOL:automatic] synonym: "nerve of digitus pedis" EXACT [OBOL:automatic] synonym: "nerve of foot digit" EXACT [OBOL:automatic] synonym: "nerve of toe" EXACT [OBOL:automatic] synonym: "toe nerve" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb nerve" EXACT [OBOL:automatic] synonym: "nerve of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "nerve of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit nerve" EXACT [OBOL:automatic] xref: MA:0000649 ! foot digit nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001466 ! pedal digit xref: SCTID:300056004 ! Digital nerve of foot synonym: "foot digit nerve" EXACT [MA:0000649] [Term] id: UBERON:0003436 name: shoulder nerve def: "A nerve that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of shoulder" EXACT [OBOL:automatic] xref: MA:0000634 ! shoulder nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001467 ! shoulder [Term] id: UBERON:0003437 name: eyelid nerve def: "A nerve that is part of a eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "blepharon nerve" EXACT [OBOL:automatic] synonym: "nerve of blepharon" EXACT [OBOL:automatic] synonym: "nerve of eyelid" EXACT [OBOL:automatic] xref: MA:0001255 ! eyelid nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001711 ! eyelid [Term] id: UBERON:0003438 name: iris nerve def: "A nerve that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of iris" EXACT [OBOL:automatic] xref: MA:0001291 ! iris nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001769 ! iris [Term] id: UBERON:0003439 name: nerve of trunk region def: "A nerve that is part of a trunk [Automatically generated definition]." [OBOL:automatic] comment: todo - check EMAPA synonym: "nerve of torso" EXACT [OBOL:automatic] synonym: "nerve of trunk" EXACT [OBOL:automatic] synonym: "torso nerve" EXACT [OBOL:automatic] synonym: "trunk nerve" EXACT [MA:0000515] xref: MA:0000515 ! trunk nerve xref: EMAPA:16986 ! nerve trunk (also: UBERON:0001147 'trunk of peripheral nerve') (also: UBERON:0002464 'nerve trunk') (also: UBERON:0004295 'sympathetic nerve trunk') intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0003440 name: limb nerve def: "A nerve that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of limb" EXACT [OBOL:automatic] xref: MA:0000693 ! limb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002101 ! limb xref: SCTID:359923002 ! Nervous structure of limb [Term] id: UBERON:0003441 name: forelimb nerve def: "A nerve that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing nerve" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "anteriormost limb nerve" EXACT [OBOL:automatic] synonym: "fore limb nerve" EXACT [OBOL:automatic] synonym: "nerve of anteriormost limb" EXACT [OBOL:automatic] synonym: "nerve of fore limb" EXACT [OBOL:automatic] synonym: "nerve of forelimb" EXACT [OBOL:automatic] synonym: "nerve of superior member" EXACT [OBOL:automatic] synonym: "nerve of upper extremity" EXACT [OBOL:automatic] synonym: "superior member nerve" EXACT [OBOL:automatic] synonym: "upper extremity nerve" EXACT [OBOL:automatic] xref: MA:0000616 ! forelimb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003442 name: hindlimb nerve def: "A nerve that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb nerve" EXACT [OBOL:automatic] synonym: "inferior member nerve" EXACT [OBOL:automatic] synonym: "lower extremity nerve" EXACT [OBOL:automatic] synonym: "nerve of hind limb" EXACT [OBOL:automatic] synonym: "nerve of hindlimb" EXACT [OBOL:automatic] synonym: "nerve of inferior member" EXACT [OBOL:automatic] synonym: "nerve of lower extremity" EXACT [OBOL:automatic] xref: MA:0000664 ! hindlimb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003443 name: thoracic cavity nerve def: "A nerve that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest nerve" EXACT [OBOL:automatic] synonym: "cavity of thorax nerve" EXACT [OBOL:automatic] synonym: "chest cavity nerve" EXACT [OBOL:automatic] synonym: "nerve of cavity of chest" EXACT [OBOL:automatic] synonym: "nerve of cavity of thorax" EXACT [OBOL:automatic] synonym: "nerve of chest cavity" EXACT [OBOL:automatic] synonym: "nerve of pectoral cavity" EXACT [OBOL:automatic] synonym: "nerve of thoracic cavity" EXACT [OBOL:automatic] synonym: "pectoral cavity nerve" EXACT [OBOL:automatic] xref: MA:0000556 ! thoracic cavity nerve intersection_of: UBERON:0001021 ! nerve intersection_of: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003444 name: pelvis nerve def: "A nerve that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of pelvis" EXACT [OBOL:automatic] xref: MA:0000542 ! pelvis nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002355 ! pelvis [Term] id: UBERON:0003445 name: pes nerve def: "A nerve that is part of a foot [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of foot" EXACT [OBOL:automatic] synonym: "nerve of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb nerve" EXACT [OBOL:automatic] synonym: "autopod of hind limb nerve" EXACT [OBOL:automatic] synonym: "autopod of hindlimb nerve" EXACT [OBOL:automatic] synonym: "autopod of inferior member nerve" EXACT [OBOL:automatic] synonym: "autopod of lower extremity nerve" EXACT [OBOL:automatic] synonym: "distal free limb segment of hind limb nerve" EXACT [OBOL:automatic] synonym: "distal free limb segment of hindlimb nerve" EXACT [OBOL:automatic] synonym: "distal free limb segment of inferior member nerve" EXACT [OBOL:automatic] synonym: "distal free limb segment of lower extremity nerve" EXACT [OBOL:automatic] synonym: "hind limb autopod nerve" EXACT [OBOL:automatic] synonym: "hind limb distal free limb segment nerve" EXACT [OBOL:automatic] synonym: "hindlimb autopod nerve" EXACT [OBOL:automatic] synonym: "hindlimb distal free limb segment nerve" EXACT [OBOL:automatic] synonym: "inferior member autopod nerve" EXACT [OBOL:automatic] synonym: "inferior member distal free limb segment nerve" EXACT [OBOL:automatic] synonym: "lower extremity autopod nerve" EXACT [OBOL:automatic] synonym: "lower extremity distal free limb segment nerve" EXACT [OBOL:automatic] synonym: "nerve of autopod of hind limb" EXACT [OBOL:automatic] synonym: "nerve of autopod of hindlimb" EXACT [OBOL:automatic] synonym: "nerve of autopod of inferior member" EXACT [OBOL:automatic] synonym: "nerve of autopod of lower extremity" EXACT [OBOL:automatic] synonym: "nerve of distal free limb segment of hind limb" EXACT [OBOL:automatic] synonym: "nerve of distal free limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "nerve of distal free limb segment of inferior member" EXACT [OBOL:automatic] synonym: "nerve of distal free limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "nerve of hind limb autopod" EXACT [OBOL:automatic] synonym: "nerve of hind limb distal free limb segment" EXACT [OBOL:automatic] synonym: "nerve of hindlimb autopod" EXACT [OBOL:automatic] synonym: "nerve of hindlimb distal free limb segment" EXACT [OBOL:automatic] synonym: "nerve of inferior member autopod" EXACT [OBOL:automatic] synonym: "nerve of inferior member distal free limb segment" EXACT [OBOL:automatic] synonym: "nerve of lower extremity autopod" EXACT [OBOL:automatic] synonym: "nerve of lower extremity distal free limb segment" EXACT [OBOL:automatic] xref: MA:0000653 ! foot nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002387 ! pes synonym: "foot nerve" EXACT [MA:0000653] [Term] id: UBERON:0003446 name: ankle nerve def: "A nerve that is part of an ankle [Automatically generated definition]." [OBOL:automatic] comment: AO notes: FMA placement dubious synonym: "nerve of ankle" EXACT [OBOL:automatic] synonym: "tarsal region nerve" EXACT [UBERON:cjm] xref: MA:0000640 ! ankle nerve xref: FMA:86901 ! Neural network of ankle intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0004454 ! tarsal region synonym: "neural network of ankle" RELATED [FMA:86901] [Term] id: UBERON:0003447 name: digit nerve of manus def: "A nerve that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "digit of hand nerve" EXACT [OBOL:automatic] synonym: "digitus manus nerve" EXACT [OBOL:automatic] synonym: "finger nerve" EXACT [OBOL:automatic] synonym: "nerve of digit of hand" EXACT [OBOL:automatic] synonym: "nerve of digitus manus" EXACT [OBOL:automatic] synonym: "nerve of finger" EXACT [OBOL:automatic] synonym: "nerve of hand digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "nerve of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit nerve" EXACT [OBOL:automatic] synonym: "hand digit nerve" EXACT [MA:0000625] xref: MA:0000625 ! hand digit nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002389 ! manual digit xref: SCTID:181015006 ! Digital nerve of hand [Term] id: UBERON:0003448 name: manus nerve def: "A nerve that is part of a manus [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of manus" EXACT [OBOL:automatic] synonym: "nerve of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "arm autopod nerve" EXACT [OBOL:automatic] synonym: "arm distal free limb segment nerve" EXACT [OBOL:automatic] synonym: "autopod of arm nerve" EXACT [OBOL:automatic] synonym: "autopod of brachial region nerve" EXACT [OBOL:automatic] synonym: "autopod of proximal segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "brachial region autopod nerve" EXACT [OBOL:automatic] synonym: "brachial region distal free limb segment nerve" EXACT [OBOL:automatic] synonym: "distal free limb segment of arm nerve" EXACT [OBOL:automatic] synonym: "distal free limb segment of brachial region nerve" EXACT [OBOL:automatic] synonym: "distal free limb segment of proximal segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "nerve of arm autopod" EXACT [OBOL:automatic] synonym: "nerve of arm distal free limb segment" EXACT [OBOL:automatic] synonym: "nerve of autopod of arm" EXACT [OBOL:automatic] synonym: "nerve of autopod of brachial region" EXACT [OBOL:automatic] synonym: "nerve of autopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of brachial region autopod" EXACT [OBOL:automatic] synonym: "nerve of brachial region distal free limb segment" EXACT [OBOL:automatic] synonym: "nerve of distal free limb segment of arm" EXACT [OBOL:automatic] synonym: "nerve of distal free limb segment of brachial region" EXACT [OBOL:automatic] synonym: "nerve of distal free limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of proximal segment of free upper limb autopod" EXACT [OBOL:automatic] synonym: "nerve of proximal segment of free upper limb distal free limb segment" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb autopod nerve" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb distal free limb segment nerve" EXACT [OBOL:automatic] xref: MA:0000629 ! hand nerve synonym: "hand nerve" EXACT [MA:0000629] intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002398 ! manus [Term] id: UBERON:0003449 name: tail intervertebral disc def: "An intervertebral disk that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "intervertebral disc of post-vent region" EXACT [OBOL:automatic] synonym: "intervertebral disc of tail" EXACT [OBOL:automatic] synonym: "intervertebral disk of post-vent region" EXACT [OBOL:automatic] synonym: "intervertebral disk of tail" EXACT [OBOL:automatic] synonym: "post-vent region intervertebral disc" EXACT [OBOL:automatic] synonym: "post-vent region intervertebral disk" EXACT [OBOL:automatic] synonym: "post-vent region spinal disc" EXACT [OBOL:automatic] synonym: "spinal disc of post-vent region" EXACT [OBOL:automatic] synonym: "spinal disc of tail" EXACT [OBOL:automatic] synonym: "tail intervertebral disk" EXACT [OBOL:automatic] synonym: "tail spinal disc" EXACT [OBOL:automatic] xref: MA:0000698 ! tail intervertebral disc xref: EMAPA:19592 ! intervertebral disc of axial skeleton of skeleton of tail of embryo intersection_of: UBERON:0001066 ! intervertebral disk intersection_of: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0007252 name: intervertebral disk of cervical vertebra synonym: "cervical intervertebral disc" EXACT [FMA:13895] synonym: "intervertebral disc of cervical region" EXACT [EMAPA:19415] xref: FMA:13895 ! intervertebral disk of cervical vertebra xref: EMAPA:19415 ! intervertebral disc of cervical region intersection_of: UBERON:0001066 ! intervertebral disk intersection_of: part_of UBERON:0006072 ! cervical region of vertebral column xref: SCTID:68818006 ! Structure of cervical intervertebral disc def: "An intervertebral disk that is part of a cervical region of vertebral column." [OBOL:automatic] [Term] id: UBERON:0007254 name: intervertebral disk of thoracic vertebra synonym: "intervertebral disc of thoracic region" EXACT [EMAPA:19489] xref: EMAPA:19489 ! intervertebral disc of thoracic region xref: FMA:10455 ! intervertebral disk of thoracic vertebra intersection_of: UBERON:0001066 ! intervertebral disk intersection_of: part_of UBERON:0006073 ! thoracic region of vertebral column def: "An intervertebral disk that is part of a thoracic region of vertebral column." [OBOL:automatic] [Term] id: UBERON:0007255 name: intervertebral disk of lumbar vertebra synonym: "intervertebral disc of lumbar region" EXACT [EMAPA:19468] xref: EMAPA:19468 ! intervertebral disc of lumbar region xref: FMA:13894 ! intervertebral disk of lumbar vertebra intersection_of: UBERON:0001066 ! intervertebral disk intersection_of: part_of UBERON:0006074 ! lumbar region of vertebral column def: "An intervertebral disk that is part of a lumbar region of vertebral column." [OBOL:automatic] [Term] id: UBERON:0007257 name: intervertebral disk of sacral vertebra synonym: "intervertebral disc of sacral region" EXACT [EMAPA:19575] xref: EMAPA:19575 ! intervertebral disc of sacral region intersection_of: UBERON:0001066 ! intervertebral disk intersection_of: part_of UBERON:0006075 ! sacral region of vertebral column def: "An intervertebral disk that is part of a sacral region of vertebral column." [OBOL:automatic] [Term] id: UBERON:0007260 name: intervertebral disk of third cervical vertebra synonym: "C3 intervertebral disk" EXACT [FMA:13896] synonym: "intervertebral disk, C3-C4" EXACT [FMA:13896] xref: FMA:13896 ! intervertebral disk of third cervical vertebra xref: EMAPA:19422 ! C3 of intervertebral disc of cervical region is_a: UBERON:0007252 ! intervertebral disk of cervical vertebra [Term] id: UBERON:0007261 name: intervertebral disk of fourth cervical vertebra synonym: "intervertebral disc of fourth cervical vertebra" EXACT [FMA:13897] synonym: "intervertebral disk, C4-C5" EXACT [FMA:13897] xref: FMA:13897 ! intervertebral disk of fourth cervical vertebra xref: EMAPA:19425 ! C4 of intervertebral disc of cervical region is_a: UBERON:0007252 ! intervertebral disk of cervical vertebra xref: SCTID:361748005 ! Entire intervertebral disc of fourth cervical vertebra [Term] id: UBERON:0007262 name: intervertebral disk of fifth cervical vertebra synonym: "intervertebral disc of fifth cervical vertebra" EXACT [FMA:13898] synonym: "intervertebral disk, C5-C6" EXACT [FMA:13898] xref: FMA:13898 ! intervertebral disk of fifth cervical vertebra xref: EMAPA:19428 ! C5 of intervertebral disc of cervical region is_a: UBERON:0007252 ! intervertebral disk of cervical vertebra xref: SCTID:361749002 ! Entire intervertebral disc of fifth cervical vertebra [Term] id: UBERON:0007263 name: intervertebral disk of sixth cervical vertebra synonym: "intervertebral disk, C6-C7" EXACT [FMA:13899] xref: FMA:13899 ! intervertebral disk of sixth cervical vertebra xref: EMAPA:19460 ! C6 of intervertebral disc of cervical region is_a: UBERON:0007252 ! intervertebral disk of cervical vertebra [Term] id: UBERON:0007264 name: intervertebral disk of seventh cervical vertebra synonym: "intervertebral disk, C7-T1" EXACT [FMA:13900] xref: FMA:13900 ! intervertebral disk of seventh cervical vertebra xref: EMAPA:19463 ! C7 of intervertebral disc of cervical region is_a: UBERON:0007252 ! intervertebral disk of cervical vertebra [Term] id: UBERON:0007265 name: intervertebral disk of axis synonym: "C2 disk" EXACT [FMA:25058] synonym: "C2 intervertebral disk" EXACT [FMA:25058] synonym: "intervertebral disc of cervical vertebra 2" EXACT [FMA:25058] synonym: "intervertebral disk of cervical vertebra 2" EXACT [FMA:25058] synonym: "intervertebral disk, C2-C3" EXACT [FMA:25058] synonym: "second cervical intervertebral disk" EXACT [FMA:25058] xref: FMA:25058 ! intervertebral disk of axis (also: UBERON:0007266 'intervertebral disk of atlas') xref: EMAPA:19419 ! C2 of intervertebral disc of cervical region is_a: UBERON:0007252 ! intervertebral disk of cervical vertebra [Term] id: UBERON:0007266 name: intervertebral disk of atlas synonym: "C1 disk" EXACT [] synonym: "C1 intervertebral disk" EXACT [] synonym: "intervertebral disc of cervical vertebra 1" EXACT [] synonym: "intervertebral disk of cervical vertebra 1" EXACT [] synonym: "intervertebral disk, C1-C2" EXACT [] synonym: "first cervical intervertebral disk" EXACT [] xref: FMA:25058 ! intervertebral disk of axis (also: UBERON:0007265 'intervertebral disk of axis') xref: EMAPA:19416 ! C1 of intervertebral disc of cervical region is_a: UBERON:0007252 ! intervertebral disk of cervical vertebra [Term] id: UBERON:0003450 name: upper jaw incisor def: "An incisor tooth that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "premaxillary tooth" RELATED [UBERON:cjm] synonym: "upper incisor" EXACT [OBOL:automatic, UBERON:cjm] synonym: "incisor of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "incisor of upper jaw" EXACT [OBOL:automatic] synonym: "incisor tooth of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "incisor tooth of upper jaw" EXACT [OBOL:automatic] synonym: "palatoquadrate arch incisor" EXACT [OBOL:automatic] synonym: "palatoquadrate arch incisor tooth" EXACT [OBOL:automatic] synonym: "upper jaw incisor tooth" EXACT [OBOL:automatic] synonym: "upper primary incisor tooth" NARROW [FMA:84214] xref: MA:0001601 ! upper jaw incisor xref: ncithesaurus:Upper_Jaw_Incisor ! Upper Jaw Incisor xref: EHDAA2:0002121 ! upper jaw incisor xref: EMAPA:17939 ! incisor of tooth of upper jaw xref: FMA:55712 ! Upper secondary incisor tooth xref: SCTID:421578001 ! Entire primary upper incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: attaches_to UBERON:0002244 ! premaxilla synonym: "upper secondary incisor tooth" RELATED [FMA:55712] synonym: "maxillary secondary incisor tooth" RELATED [FMA:55712] synonym: "upper permanent incisor tooth" RELATED [FMA:55712] xref: UMLS:C1710579 [Term] id: UBERON:0003451 name: lower jaw incisor def: "An incisor tooth that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "lower incisor" EXACT [OBOL:automatic, UBERON:cjm] synonym: "incisor of lower jaw" EXACT [OBOL:automatic] synonym: "incisor of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "incisor tooth of lower jaw" EXACT [OBOL:automatic] synonym: "incisor tooth of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "lower jaw incisor tooth" EXACT [OBOL:automatic] synonym: "ventral mandibular arch incisor" EXACT [OBOL:automatic] synonym: "ventral mandibular arch incisor tooth" EXACT [OBOL:automatic] synonym: "mandibular incisor" EXACT [BTO:0001942] synonym: "lower primary incisor tooth" NARROW [FMA:84215] xref: MA:0001600 ! lower jaw incisor xref: ncithesaurus:Lower_Jaw_Incisor ! Lower Jaw Incisor xref: EHDAA2:0001021 ! lower jaw incisor xref: BTO:0001942 ! mandibular incisor xref: EMAPA:17918 ! incisor of tooth of lower jaw xref: FMA:55713 ! Lower secondary incisor tooth xref: SCTID:420793009 ! Entire primary lower incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0001710 ! lower jaw region synonym: "lower secondary incisor tooth" RELATED [FMA:55713] synonym: "lower permanent incisor tooth" RELATED [FMA:55713] synonym: "mandibular secondary incisor tooth" RELATED [FMA:55713] xref: UMLS:C1708755 [Term] id: UBERON:0003666 name: upper jaw molar def: "A molar tooth that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "upper molar" RELATED [UBERON:cjm] synonym: "upper molar tooth" EXACT [UBERON:cjm] synonym: "molar tooth of upper jaw" EXACT [OBOL:automatic] synonym: "upper jaw molar tooth" EXACT [OBOL:automatic] synonym: "upper primary molar tooth" NARROW [FMA:84210] xref: MA:0001603 ! upper jaw molar xref: ncithesaurus:Upper_Jaw_Molar ! Upper Jaw Molar xref: EHDAA2:0002125 ! upper jaw molar xref: EMAPA:17942 ! molar of tooth of upper jaw xref: FMA:55720 ! Upper secondary molar tooth xref: EHDAA:8053 ! molar of tooth of upper jaw intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: attaches_to UBERON:0002397 ! maxilla synonym: "upper secondary molar tooth" RELATED [FMA:55720] synonym: "maxillary secondary molar tooth" RELATED [FMA:55720] synonym: "upper permanent molar tooth" RELATED [FMA:55720] xref: UMLS:C1710580 [Term] id: UBERON:0003667 name: lower jaw molar def: "A molar tooth that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "lower molar" RELATED [UBERON:cjm] synonym: "lower molar tooth" EXACT [UBERON:cjm] synonym: "lower jaw molar tooth" EXACT [OBOL:automatic] synonym: "molar tooth of lower jaw" EXACT [OBOL:automatic] synonym: "lower primary molar tooth" NARROW [FMA:84213] xref: MA:0001602 ! lower jaw molar xref: ncithesaurus:Lower_Jaw_Molar ! Lower Jaw Molar xref: EHDAA2:0001025 ! lower jaw molar xref: EMAPA:17921 ! molar of tooth of lower jaw xref: EHDAA:8017 ! molar of tooth of lower jaw xref: FMA:55721 ! Lower secondary molar tooth intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: attaches_to UBERON:0004742 ! dentary synonym: "lower secondary molar tooth" RELATED [FMA:55721] synonym: "lower permanent molar tooth" RELATED [FMA:55721] synonym: "mandibular secondary molar tooth" RELATED [FMA:55721] xref: UMLS:C1708756 [Term] id: UBERON:0013616 name: primary molar tooth comment: todo - logical definition synonym: "deciduous molar tooth" EXACT [FMA:84206] synonym: "temporary molar tooth" EXACT [FMA:84206] synonym: "primary molar tooth" EXACT [FMA:84206] intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0007116 ! primary dentition xref: FMA:84206 ! primary molar tooth [Term] id: UBERON:0013618 name: secondary molar tooth synonym: "permanent molar tooth" EXACT [FMA:84207] intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0007774 ! secondary dentition xref: FMA:84207 ! secondary molar tooth xref: SCTID:421593002 ! Entire permanent molar tooth synonym: "secondary molar tooth" EXACT [FMA:84207] [Term] id: UBERON:0013617 name: upper primary molar tooth synonym: "upper deciduous molar tooth" EXACT [FMA:84210] intersection_of: UBERON:0013616 ! primary molar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region xref: FMA:84210 ! upper primary molar tooth xref: SCTID:422318005 ! Entire primary upper molar tooth synonym: "upper primary molar tooth" EXACT [FMA:84210] [Term] id: UBERON:0013619 name: upper secondary molar tooth synonym: "maxillary secondary molar tooth" EXACT [FMA:55720] synonym: "upper permanent molar tooth" EXACT [FMA:55720] intersection_of: UBERON:0013618 ! secondary molar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region xref: FMA:55720 ! upper secondary molar tooth synonym: "upper secondary molar tooth" EXACT [FMA:55720] [Term] id: UBERON:0013620 name: lower primary molar tooth synonym: "lower deciduous molar tooth" EXACT [FMA:84213] intersection_of: UBERON:0013616 ! primary molar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region xref: FMA:84213 ! lower primary molar tooth xref: SCTID:421482001 ! Entire primary lower molar tooth [Term] id: UBERON:0013621 name: lower secondary molar tooth synonym: "lower permanent molar tooth" EXACT [FMA:55721] synonym: "mandibular secondary molar tooth" EXACT [FMA:55721] intersection_of: UBERON:0013618 ! secondary molar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region xref: FMA:55721 ! lower secondary molar tooth [Term] id: UBERON:0003455 name: inner renal medulla loop of henle def: "A loop of Henle that is part of a inner medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "Henle loop of inner medulla of kidney" EXACT [OBOL:automatic] synonym: "Henle loop of inner renal medulla" EXACT [OBOL:automatic] synonym: "Henle loop of inner zone of medulla of kidney" EXACT [OBOL:automatic] synonym: "Henle loop of inner zone of renal medulla" EXACT [OBOL:automatic] synonym: "henle's loop of inner medulla of kidney" EXACT [OBOL:automatic] synonym: "henle's loop of inner renal medulla" EXACT [OBOL:automatic] synonym: "henle's loop of inner zone of medulla of kidney" EXACT [OBOL:automatic] synonym: "henle's loop of inner zone of renal medulla" EXACT [OBOL:automatic] synonym: "inner medulla of kidney Henle loop" EXACT [OBOL:automatic] synonym: "inner medulla of kidney henle's loop" EXACT [OBOL:automatic] synonym: "inner medulla of kidney loop of Henle" EXACT [OBOL:automatic] synonym: "inner renal medulla Henle loop" EXACT [OBOL:automatic] synonym: "inner renal medulla henle's loop" EXACT [OBOL:automatic] synonym: "inner renal medulla loop of Henle" EXACT [OBOL:automatic] synonym: "inner zone of medulla of kidney Henle loop" EXACT [OBOL:automatic] synonym: "inner zone of medulla of kidney henle's loop" EXACT [OBOL:automatic] synonym: "inner zone of medulla of kidney loop of Henle" EXACT [OBOL:automatic] synonym: "inner zone of renal medulla Henle loop" EXACT [OBOL:automatic] synonym: "inner zone of renal medulla henle's loop" EXACT [OBOL:automatic] synonym: "inner zone of renal medulla loop of Henle" EXACT [OBOL:automatic] synonym: "loop of Henle of inner medulla of kidney" EXACT [OBOL:automatic] synonym: "loop of Henle of inner renal medulla" EXACT [OBOL:automatic] synonym: "loop of Henle of inner zone of medulla of kidney" EXACT [OBOL:automatic] synonym: "loop of Henle of inner zone of renal medulla" EXACT [OBOL:automatic] xref: MA:0002623 ! inner renal medulla loop of henle intersection_of: UBERON:0001288 ! loop of Henle intersection_of: part_of UBERON:0001294 ! inner medulla of kidney synonym: "kidney inner medulla loop of henle" EXACT [MA:0002623] [Term] id: UBERON:0003456 name: respiratory system lymphatic vessel def: "A lymphatic vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius lymph vessel" EXACT [OBOL:automatic] synonym: "apparatus respiratorius lymphatic vessel" EXACT [OBOL:automatic] synonym: "lymph vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lymph vessel of respiratory system" EXACT [OBOL:automatic] synonym: "lymphatic vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lymphatic vessel of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system lymph vessel" EXACT [OBOL:automatic] xref: MA:0001824 ! respiratory system lymphatic vessel intersection_of: UBERON:0001473 ! lymphatic vessel intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003457 name: head bone def: "A bone that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head bone" EXACT [OBOL:automatic] synonym: "adult head bone organ" EXACT [OBOL:automatic] synonym: "bone of adult head" EXACT [OBOL:automatic] synonym: "bone of head" EXACT [OBOL:automatic] synonym: "bone organ of adult head" EXACT [OBOL:automatic] synonym: "bone organ of head" EXACT [OBOL:automatic] synonym: "head bone organ" EXACT [OBOL:automatic] xref: MA:0000576 ! head bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000033 ! head xref: SCTID:118646007 ! Entire bone of head [Term] id: UBERON:0003458 name: neck bone def: "A bone that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "bone of neck" EXACT [OBOL:automatic] synonym: "bone of neck (volume)" EXACT [OBOL:automatic] synonym: "bone organ of neck" EXACT [OBOL:automatic] synonym: "bone organ of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) bone" EXACT [OBOL:automatic] synonym: "neck (volume) bone organ" EXACT [OBOL:automatic] synonym: "neck bone organ" EXACT [OBOL:automatic] xref: MA:0000584 ! neck bone xref: OpenCyc:Mx4rvnpJSJwpEbGdrcN5Y29ycA ! neck bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003459 name: chest bone def: "A bone that is part of a chest [Automatically generated definition]." [OBOL:automatic] synonym: "anterior thoracic region bone" EXACT [OBOL:automatic] synonym: "anterior thoracic region bone organ" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax bone" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax bone organ" EXACT [OBOL:automatic] synonym: "bone of anterior thoracic region" EXACT [OBOL:automatic] synonym: "bone of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "bone of chest" EXACT [OBOL:automatic] synonym: "bone of front of thorax" EXACT [OBOL:automatic] synonym: "bone organ of anterior thoracic region" EXACT [OBOL:automatic] synonym: "bone organ of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "bone organ of chest" EXACT [OBOL:automatic] synonym: "bone organ of front of thorax" EXACT [OBOL:automatic] synonym: "chest bone organ" EXACT [OBOL:automatic] synonym: "front of thorax bone" EXACT [OBOL:automatic] synonym: "front of thorax bone organ" EXACT [OBOL:automatic] xref: MA:0000547 ! chest bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001443 ! chest [Term] id: UBERON:0003460 name: arm bone def: "A bone that is part of the region of the forelimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia" [UBERON:cjm] synonym: "bone of upper extremity" EXACT [GAID:178] synonym: "arm bone organ" EXACT [OBOL:automatic] synonym: "bone of arm" EXACT [OBOL:automatic] synonym: "bone of brachial region" EXACT [OBOL:automatic] synonym: "bone of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone organ of arm" EXACT [OBOL:automatic] synonym: "bone organ of brachial region" EXACT [OBOL:automatic] synonym: "bone organ of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "brachial region bone" EXACT [OBOL:automatic] synonym: "brachial region bone organ" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb bone" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb bone organ" EXACT [OBOL:automatic] xref: MA:0000592 ! arm bone xref: OpenCyc:Mx4rwKTXoJwpEbGdrcN5Y29ycA ! arm bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001440 ! forelimb skeleton [Term] id: UBERON:0008962 ! forelimb bone def: "A bone that is part of a forelimb region. Examples: any manus phalanx, humerus. Counter-examples: scapula (it is part of the pectoral girdle)" [UBERON:cjm] name: forelimb bone synonym: "wing bone" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "free forelimb bone" EXACT [UBERON:cjm, UBERONREF:0000003] synonym: "wing bone" NARROW SENSU [Geisha:syn, NCBITaxon:8782] intersection_of: UBERON:0002428 ! limb bone intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0001440 ! forelimb skeleton xref: GAID:178 ! bones of upper extremity xref: MESH:A02.835.232.087 ! bones of upper extremity xref: ncithesaurus:Bone_of_the_Upper_Extremity ! Bone of the Upper Extremity xref: SCTID:368532003 ! Entire bone of upper extremity relationship: develops_from UBERON:0010883 ! forelimb bone cartilaginous condensation xref: UMLS:C0003793 [Term] id: UBERON:0010883 name: forelimb bone cartilaginous condensation synonym: "wing bone cartilaginous condensation" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] subset: grouping_class intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0008962 ! forelimb bone ! forelimb bone relationship: part_of UBERON:0001440 ! forelimb skeleton relationship: develops_from UBERON:0010884 ! forelimb bone pre-cartilage condensation def: "A cartilaginous condensation that develops_into a forelimb bone." [OBOL:automatic] [Term] id: UBERON:0010884 name: forelimb bone pre-cartilage condensation synonym: "wing bone pre-cartilage condensation" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] subset: grouping_class intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0008962 ! forelimb bone ! forelimb bone relationship: part_of UBERON:0001440 ! forelimb skeleton def: "A pre-cartilage condensation that develops_into a forelimb bone." [OBOL:automatic] [Term] id: UBERON:0010741 name: bone of pectoral complex def: "A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin." [UBERON:cjm, UBERONREF:0000003] comment: AO notes - note that the MA class includes girdle parts so it belongs here; Editor notes: considering adding pectoral and pelvic complex skeleton classes synonym: "bone of forelimb or pectoral fin or pectoral girdle" RELATED [UBERON:cjm, UBERONREF:0000003] synonym: "forelimb bone" RELATED [MA:0000612, UBERONREF:0000003] synonym: "wing bone" NARROW SENSU [UBERONREF:0000003] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: part_of UBERON:0002091 ! appendicular skeleton xref: MA:0000612 ! forelimb bone [Term] id: UBERON:0003461 name: shoulder bone def: "A bone that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] comment: AO notes: this is a forelimb bone in MA, but this would lead to part-disjointness violations. Subtypes are clavicle, scapula, humerus synonym: "bone of shoulder" EXACT [OBOL:automatic] synonym: "bone organ of shoulder" EXACT [OBOL:automatic] synonym: "shoulder bone organ" EXACT [OBOL:automatic] xref: MA:0000631 ! shoulder bone is_a: UBERON:0010741 {source="MA", notes="UBERONREF:0000003"} ! bone of pectoral complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001467 ! shoulder relationship: part_of UBERON:0007831 ! pectoral girdle skeleton [Term] id: UBERON:0003462 name: facial bone def: "A bone that is part of a facial skeleton [Automatically generated definition]." [OBOL:automatic] comment: Editors note: test whether 'facial bone' is an exact synonym synonym: "facial bone" EXACT [EMAPA:19019] synonym: "bone of facial skeleton" EXACT [OBOL:automatic] synonym: "bone of viscerocranium" EXACT [OBOL:automatic] synonym: "viscerocranium bone" EXACT [OBOL:automatic] synonym: "facial skeleton bone" EXACT [OBOL:automatic] xref: MA:0001482 ! viscerocranium bone xref: EMAPA:19019 ! facial bone xref: SCTID:181799005 ! Entire facial bone xref: ncithesaurus:Facial_Bone ! Facial Bone synonym: "facial bone" EXACT [EMAPA:19019] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0011156 ! facial skeleton relationship: part_of UBERON:0011156 {source="MA"} ! facial skeleton xref: UMLS:C0015455 [Term] id: UBERON:0003463 name: trunk bone def: "A bone that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "bone of torso" EXACT [OBOL:automatic] synonym: "bone of trunk" EXACT [OBOL:automatic] synonym: "bone organ of torso" EXACT [OBOL:automatic] synonym: "bone organ of trunk" EXACT [OBOL:automatic] synonym: "torso bone" EXACT [OBOL:automatic] synonym: "torso bone organ" EXACT [OBOL:automatic] synonym: "trunk bone organ" EXACT [OBOL:automatic] xref: MA:0000512 ! trunk bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002100 ! trunk xref: SCTID:427358002 ! Entire bone organ of trunk [Term] id: UBERON:0003464 name: hindlimb bone def: "A bone that is part of a hindlimb region. Examples: any pes phalanx, femur. Counter-examples: ischium, pubis (they are part of the pelvic girdle)" [UBERON:cjm] comment: Note that the MA class is actually bone of pelvic complex; in contrast the NCIT class excludes ilium etc synonym: "bone of hind limb" EXACT [OBOL:automatic] synonym: "bone of hindlimb" EXACT [OBOL:automatic] synonym: "bone of inferior member" EXACT [OBOL:automatic] synonym: "bone of lower extremity" EXACT [OBOL:automatic] synonym: "bone organ of hind limb" EXACT [OBOL:automatic] synonym: "bone organ of hindlimb" EXACT [OBOL:automatic] synonym: "bone organ of inferior member" EXACT [OBOL:automatic] synonym: "bone organ of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb bone" EXACT [OBOL:automatic] synonym: "hind limb bone organ" EXACT [OBOL:automatic] synonym: "hindlimb bone organ" EXACT [OBOL:automatic] synonym: "inferior member bone" EXACT [OBOL:automatic] synonym: "inferior member bone organ" EXACT [OBOL:automatic] synonym: "lower extremity bone" EXACT [OBOL:automatic] synonym: "lower extremity bone organ" EXACT [OBOL:automatic] xref: GAID:198 ! leg bone xref: EFO:0003842 ! bone of lower extremity intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0001441 ! hindlimb skeleton xref: ncithesaurus:Bone_of_the_Lower_Extremity ! Bone of the Lower Extremity xref: SCTID:361370006 ! Entire bone of lower extremity relationship: develops_from UBERON:0010885 ! hindlimb bone cartilaginous condensation xref: UMLS:C0448188 [Term] id: UBERON:0010885 name: hindlimb bone cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0003464 ! hindlimb bone relationship: part_of UBERON:0001441 ! hindlimb skeleton relationship: develops_from UBERON:0010886 ! hindlimb bone pre-cartilage condensation def: "A cartilaginous condensation that develops_into a hindlimb bone." [OBOL:automatic] [Term] id: UBERON:0010886 name: hindlimb bone pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0003464 ! hindlimb bone relationship: part_of UBERON:0001441 ! hindlimb skeleton def: "A pre-cartilage condensation that develops_into a hindlimb bone." [OBOL:automatic] [Term] id: UBERON:0010742 name: bone of pelvic complex def: "A bone that is part of a pelvic complex. Examples: pubis, ischium, fot phalanx, any tarsal bone, any bone of the pelvic fin or girdle." [UBERON:cjm, UBERONREF:0000003] comment: Note that the MA class called 'hindlimb bone' belongs here, as it includes bones in the pelvic girdle synonym: "hindlimb bone" RELATED [MA:0000660, UBERONREF:0000003] is_a: UBERON:0010740 {source="MA"} ! bone of appendage girdle complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: part_of UBERON:0002091 ! appendicular skeleton xref: MA:0000660 ! hindlimb bone [Term] id: UBERON:0005893 name: leg bone def: "A bone that is part of the region of the hindlimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia. Counter-examples: any pes phalanx" [UBERON:cjm] subset: grouping_class xref: MA:0000670 ! leg bone xref: MESH:A02.835.232.500 ! leg bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000978 ! leg [Term] id: UBERON:0003466 name: forelimb zeugopod bone def: "A bone that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "wing zeugopod bone" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "antebrachial region bone" EXACT [OBOL:automatic] synonym: "antebrachial region bone organ" EXACT [OBOL:automatic] synonym: "bone of antebrachial region" EXACT [OBOL:automatic] synonym: "bone of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone of lower arm" EXACT [OBOL:automatic] synonym: "bone of lower segment of arm" EXACT [OBOL:automatic] synonym: "bone of zeugopod of arm" EXACT [OBOL:automatic] synonym: "bone organ of antebrachial region" EXACT [OBOL:automatic] synonym: "bone organ of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone organ of lower arm" EXACT [OBOL:automatic] synonym: "bone organ of lower segment of arm" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of arm" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb bone" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb bone organ" EXACT [OBOL:automatic] synonym: "lower segment of arm bone" EXACT [OBOL:automatic] synonym: "lower segment of arm bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of arm bone" EXACT [OBOL:automatic] synonym: "zeugopod of arm bone organ" EXACT [OBOL:automatic] synonym: "arm middle limb segment bone" EXACT [OBOL:automatic] synonym: "arm middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "arm zeugopod bone" EXACT [OBOL:automatic] synonym: "arm zeugopod bone organ" EXACT [OBOL:automatic] synonym: "bone of arm middle limb segment" EXACT [OBOL:automatic] synonym: "bone of arm zeugopod" EXACT [OBOL:automatic] synonym: "bone of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "bone of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "bone of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "bone of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "bone of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone organ of arm middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of arm zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone organ of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment bone" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "brachial region zeugopod bone" EXACT [OBOL:automatic] synonym: "brachial region zeugopod bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of arm bone" EXACT [OBOL:automatic] synonym: "middle limb segment of arm bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region bone" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb bone" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb bone organ" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment bone" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod bone" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region bone" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb bone" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb bone organ" EXACT [OBOL:automatic] synonym: "lower arm bone" EXACT [MA:0000598] xref: MA:0000598 ! lower arm bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002386 ! forearm relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton [Term] id: UBERON:0003467 name: sesamoid bone of gastrocnemius def: "A small sesamoid bone situated behind a condyle of the femur." [MP:0009005, https://sourceforge.net/tracker/?func=detail&atid=1205376&aid=3470151&group_id=76834, Wikipedia:Fabella] synonym: "gastrocnemius sesamoid bone" EXACT [OBOL:automatic] synonym: "m. gastrocnemius sesamoid bone" EXACT [OBOL:automatic] synonym: "sesamoid bone of m. gastrocnemius" EXACT [OBOL:automatic] synonym: "fabella" RELATED [MA:0001378] xref: MA:0001378 ! sesamoid bone of gastrocnemius is_a: UBERON:0001479 {source="MA"} ! sesamoid bone relationship: part_of UBERON:0003823 ! hindlimb zeugopod relationship: adjacent_to UBERON:0001388 ! gastrocnemius xref: galen:Fabella xref: SCTID:302749009 ! Entire fabella [Term] id: UBERON:0012104 name: sesamoid bone of the peroneus longus muscle comment: a coffee bean-shaped constant, large and regular bone. The lateral surface of the bone is convex in all directions and non-articular. The medial surface is covered with hyaline cartilage and articulates by means of a synovial joint with the corresponding facet of the cuboid bone. The histological structure and the mode of ossification of the os peroneum are identical to that of other short bones of the skeleton. synonym: "os peroneum" EXACT [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1261702/] is_a: UBERON:0001479 ! sesamoid bone relationship: part_of UBERON:0003823 ! hindlimb zeugopod relationship: connected_to UBERON:0001455 ! cuboid bone relationship: located_in UBERON:0001387 ! fibularis longus relationship: only_in_taxon NCBITaxon:9443 ! Primates [Term] id: UBERON:0003468 name: ureteric segment of renal artery def: "The ureteral branches of renal artery are small branches which supply the ureter." [Wikipedia:Ureteral_branches_of_renal_artery] synonym: "ureteric artery" BROAD [MA:0002074] xref: MA:0002074 ! ureteric artery xref: SCTID:65376008 ! Ureteric branch of renal artery xref: FMA:70491 ! ureteric segment of renal artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000056 ! ureter relationship: branch_of UBERON:0001184 {source="FMA"} ! renal artery relationship: part_of UBERON:0001184 {source="FMA"} ! renal artery [Term] id: UBERON:0003469 name: respiratory system artery def: "An artery that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: MA:0001804 ! respiratory system artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003470 name: artery of upper lip def: "The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose." [Wikipedia:Superior_labial_artery] synonym: "arteria labialis superior" EXACT LATIN [Wikipedia:Superior_labial_artery] synonym: "ramus labialis superior arteriae facialis" EXACT LATIN [Wikipedia:Superior_labial_artery] synonym: "superior labial branch of facial artery" EXACT [FMA:49570] synonym: "superior labial artery" EXACT [FMA:49570] intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001834 ! upper lip relationship: branch_of UBERON:0001612 {source="FMA"} ! facial artery relationship: part_of UBERON:0000033 ! head xref: FMA:49570 ! superior labial artery xref: MA:0001917 ! artery of upper lip xref: SCTID:145137009 ! Entire superior labial artery [Term] id: UBERON:0003471 name: artery of lower lip def: "The Iinferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery." [Wikipedia:Inferior_labial_artery] synonym: "ramus labialis inferior arteriae facialis" EXACT LATIN [Wikipedia:Inferior_labial_artery] synonym: "arteria labialis inferior" EXACT LATIN [Wikipedia:Inferior_labial_artery] synonym: "inferior labial branch of facial artery" EXACT [FMA:49567] synonym: "ramus labialis inferior (arteria facialis)" EXACT [FMA:TA] synonym: "inferior labial artery" EXACT [FMA:49567] intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001835 ! lower lip relationship: branch_of UBERON:0001612 {source="FMA"} ! facial artery relationship: part_of UBERON:0000033 ! head xref: FMA:49567 ! inferior labial artery xref: MA:0001916 ! artery of lower lip xref: SCTID:145036002 ! Entire inferior labial artery [Term] id: UBERON:0003472 name: cerebellar artery def: "an artery that supplies blood to the cerebellum." [Wikipedia:Cerebellar_artery] xref: MA:0001933 ! cerebellar artery xref: ncithesaurus:Cerebellar_Artery ! Cerebellar Artery xref: EHDAA:5290 ! cerebellar artery xref: EHDAA2:0000228 ! cerebellar artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002037 ! cerebellum relationship: part_of UBERON:0000033 ! head xref: SCTID:278102002 ! Entire cerebellar artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e1/CerebellumArteries.jpg/250px-CerebellumArteries.jpg xref: UMLS:C0226246 [Term] id: UBERON:0003473 name: thoracic cavity artery def: "An artery that is part of a thoracic cavity[cjm]." [https://sourceforge.net/tracker/index.php?func=detail&aid=3317815&group_id=76834&atid=1205376] comment: Note that in MA, aorta is classified here - but this is problematic because the abdominal aorta is not in the thoracic cavity xref: MA:0001902 ! thoracic cavity artery intersection_of: UBERON:0001637 ! artery intersection_of: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003474 ! meningeal artery name: meningeal artery def: "One of the arteries supplying the meninix[Automatically generated definition]." [Wikipedia:Meningeal_arteries] xref: MA:0002001 ! meningeal artery xref: GAID:499 ! meningeal artery xref: MESH:A07.231.114.545 ! meningeal artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002360 ! meninx [Term] id: UBERON:0010249 name: posterior meningeal artery def: "The posterior meningeal artery are small vessels which are branches of the ascending pharyngeal artery which supply the dura mater. It passes through the mastoid foramen before entering the cranium via the jugular foramen." [Wikipedia:Posterior_meningeal_artery] synonym: "meningeal branches of the ascending pharyngeal artery" RELATED [Wikipedia:Posterior_meningeal_artery] synonym: "posterior meningeal arteries" RELATED PLURAL [Wikipedia:Posterior_meningeal_artery] synonym: "terminal branch of ascending pharyngeal artery" EXACT [FMA:49503] xref: FMA:49503 ! posterior meningeal artery xref: ncithesaurus:Posterior_Meningeal_Artery ! posterior meningeal artery is_a: UBERON:0003474 ! meningeal artery synonym: "arteria meningea posterior" RELATED LATIN [Wikipedia:Posterior_meningeal_artery] xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png xref: UMLS:C0221310 [Term] id: UBERON:0010250 name: middle meningeal artery def: "The middle meningeal artery is typically the third branch of the first part (retromandibular part) of the maxillary artery; one of the two terminal branches of the external carotid artery. After branching off the maxillary artery in the infratemporal fossa, it runs through the foramen spinosum to supply the dura mater and the calvaria. The middle meningeal artery is the largest of the three (paired) arteries which supply the meninges, the others being the anterior meningeal artery and the posterior meningeal artery. In approximately half of subjects it branches into an accessory meningeal artery. The middle meningeal artery runs beneath the pterion. It is vulnerable to injury at this point, where the skull is thin. Rupture of the artery may give rise to an epidural hematoma." [Wikipedia:Middle_meningeal_artery] synonym: "arteria meningea media" RELATED [Wikipedia:Middle_meningeal_artery] is_a: UBERON:0003474 ! meningeal artery relationship: branch_of UBERON:0001616 {source="FMA"} ! maxillary artery xref: FMA:49711 ! middle meningeal artery xref: SCTID:278100005 ! Entire middle meningeal artery synonym: "arteria meningea media" RELATED LATIN [Wikipedia:Middle_meningeal_artery] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Middle_meningeal_artery.png [Term] id: UBERON:0010251 name: anterior meningeal artery def: "a meningeal branch to the dura mater arising from the anterior ethmoidal artery." [Wikipedia:Anterior_ethmoidal_artery#Branches] comment: Editor notes: this needs checking as part of a general revision of the blood vessels and their branches - unclear if the anterior meningeal artery should be treated separately from the anterior ethmoidal artery (ie as a branch) or the same thing synonym: "anterior ethmoid arteries" RELATED [Wikipedia:Anterior_ethmoidal_artery] synonym: "anterior ethmoid artery" RELATED [Wikipedia:Anterior_ethmoidal_artery] synonym: "anterior meningeal arteries" RELATED [Wikipedia:Anterior_ethmoidal_artery] synonym: "anterior meningeal artery" RELATED [Wikipedia:Anterior_ethmoidal_artery] synonym: "anterior meningeal branch of anterior ethmoidal artery" EXACT [FMA:49993] synonym: "arteria ethmoidalis anterior" RELATED LATIN [Wikipedia:Anterior_ethmoidal_artery] synonym: "a. ethmoidalis anterior" RELATED LATIN [Wikipedia:Anterior_ethmoidal_artery] xref: FMA:49993 ! anterior meningeal branch of anterior ethmoidal artery xref: SCTID:369327009 ! Entire anterior meningeal artery is_a: UBERON:0003474 ! meningeal artery relationship: branch_of UBERON:0012318 {source="Wikipedia"} ! anterior ethmoidal artery xref: ncithesaurus:Anterior_Meningeal_Artery ! anterior meningeal artery xref: http://upload.wikimedia.org/wikipedia/commons/c/ce/Gray514.png xref: UMLS:C0226187 [Term] id: UBERON:0003475 name: ureteric vein def: "A vein that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "ureter vein" EXACT [OBOL:automatic] synonym: "vein of ureter" EXACT [OBOL:automatic] xref: MA:0002250 ! ureteric vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0003476 name: respiratory system venous blood vessel def: "A vein that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius vein" EXACT [OBOL:automatic] synonym: "respiratory system vein" EXACT [OBOL:automatic] synonym: "vein of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "vein of respiratory system" EXACT [OBOL:automatic] xref: MA:0001809 ! respiratory system venous blood vessel xref: MA:0001810 ! respiratory system vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001004 ! respiratory system [Term] id: UBERON:0013136 name: vein of lip synonym: "lip vein" EXACT [OBOL:automatic] synonym: "vena labialis" EXACT LATIN [] synonym: "labial vein" RELATED [] synonym: "labial vein of face" EXACT [] intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001833 ! lip relationship: tributary_of UBERON:0001653 {source="FMA"} ! facial vein xref: SCTID:367664002 ! Entire labial vein of face [Term] id: UBERON:0003477 name: vein of upper lip def: "The inferior labial vein is the vein receiving blood from the upper lip." [Wikipedia:Superior_labial_vein] synonym: "vena labialis superior" EXACT LATIN [] synonym: "upper lip vein" EXACT [OBOL:automatic] synonym: "superior labial vein" EXACT [FMA:52538] xref: MA:0002255 ! vein of upper lip xref: FMA:52538 ! superior labial vein xref: SCTID:422755007 ! Structure of superior labial vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001834 ! upper lip relationship: tributary_of UBERON:0001653 {source="FMA"} ! facial vein [Term] id: UBERON:0003478 name: vein of lower lip def: "The inferior labial vein is the vein receiving blood from the lower lip." [Wikipedia:Inferior_labial_vein] synonym: "vena labialis inferior" EXACT LATIN [] synonym: "lower lip vein" EXACT [OBOL:automatic] synonym: "inferior labial vein" EXACT [FMA:52541] synonym: "venae labiales inferiores" RELATED LATIN [Wikipedia:Inferior_labial_vein] xref: FMA:52541 ! Inferior labial vein xref: MA:0002253 ! vein of lower lip xref: SCTID:422955002 ! Structure of inferior labial vein xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001835 ! lower lip relationship: tributary_of UBERON:0001653 {source="FMA"} ! facial vein [Term] id: UBERON:0006202 name: ventral labial vein comment: Was obsoleted as it grouped a lip structure with an unknown MA vein, which be a genital vein consider: MA:0002260 ! ventral labial vein is_obsolete: true [Term] id: UBERON:0003479 name: thoracic cavity vein def: "A vein that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest vein" EXACT [OBOL:automatic] synonym: "cavity of thorax vein" EXACT [OBOL:automatic] synonym: "chest cavity vein" EXACT [OBOL:automatic] synonym: "pectoral cavity vein" EXACT [OBOL:automatic] synonym: "vein of cavity of chest" EXACT [OBOL:automatic] synonym: "vein of cavity of thorax" EXACT [OBOL:automatic] synonym: "vein of chest cavity" EXACT [OBOL:automatic] synonym: "vein of pectoral cavity" EXACT [OBOL:automatic] synonym: "vein of thoracic cavity" EXACT [OBOL:automatic] xref: MA:0001903 ! thoracic cavity vein intersection_of: UBERON:0001638 ! vein intersection_of: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003480 name: vein of clitoris def: "A vein that is part of a clitoris [Automatically generated definition]." [OBOL:automatic] synonym: "clitoris vein" EXACT [OBOL:automatic] xref: MA:0002252 ! vein of clitoris intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0002411 ! clitoris xref: SCTID:360819004 ! Structure of vein of clitoris [Term] id: UBERON:0013126 name: vein of abdomen subset: grouping_class comment: This class groups all veins that are in the abdomen. The term 'abdominal vein' may have specific meanings in different contexts. The lateral abdominal veins are present in fishes but usually merged or absent in tetrapods; in amphibians, the L&R abdominal veins merge into the ventral abdominal vein. TODO: mirror representation of abdominal aorta synonym: "abdominal vein" EXACT [] intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0000916 ! abdomen xref: SCTID:281473003 ! Entire abdominal vein [Term] id: UBERON:0003482 name: vein of trabecular bone def: "A portion of vein that is part of a trabecular bone tissue [Automatically generated definition]." [OBOL:automatic] synonym: "spongy bone vein" EXACT [OBOL:automatic] synonym: "trabecular bone tissue vein" EXACT [OBOL:automatic] synonym: "trabecular bone vein" EXACT [OBOL:automatic] synonym: "vein of spongy bone" EXACT [OBOL:automatic] synonym: "vein of trabecular bone tissue" EXACT [OBOL:automatic] xref: MA:0002254 ! vein of trabecular bone intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0002483 ! trabecular bone [Term] id: UBERON:0003483 name: thymus lymphoid tissue def: "A portion of lymphoid tissue that is part of a thymus [Automatically generated definition]." [OBOL:automatic] synonym: "lymphatic tissue of thymus" EXACT [OBOL:automatic] synonym: "lymphatic tissue of thymus gland" EXACT [OBOL:automatic] synonym: "lymphocytic tissue of thymus" EXACT [OBOL:automatic] synonym: "lymphocytic tissue of thymus gland" EXACT [OBOL:automatic] synonym: "lymphoid tissue of thymus" EXACT [OBOL:automatic] synonym: "lymphoid tissue of thymus gland" EXACT [OBOL:automatic] synonym: "thymus gland lymphatic tissue" EXACT [OBOL:automatic] synonym: "thymus gland lymphocytic tissue" EXACT [OBOL:automatic] synonym: "thymus gland lymphoid tissue" EXACT [OBOL:automatic] synonym: "thymus lymphatic tissue" EXACT [OBOL:automatic] synonym: "thymus lymphocytic tissue" EXACT [OBOL:automatic] synonym: "thymic lymphocytic tissue" EXACT [OBOL:automatic] xref: MA:0002673 ! thymus lymphoid tissue xref: MESH:A06.407.850 ! thymus gland (also: UBERON:0002370 'thymus') xref: ncithesaurus:Thymic_Lymphoid_Tissue ! Thymic Lymphoid Tissue intersection_of: UBERON:0001744 ! lymphoid tissue intersection_of: part_of UBERON:0002370 ! thymus xref: UMLS:C1515429 [Term] id: UBERON:0013230 name: gland of nictitating membrane comment: Consider merging with Harderian synonym: "nictitans gland" EXACT [] synonym: "gland of the third eyelid" EXACT [ncithesaurus:Gland_of_the_Third_Eyelid] intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0010207 ! nictitating membrane xref: ncithesaurus:Gland_of_the_Third_Eyelid ! gland of the third eyelid [Term] id: UBERON:0004187 name: Harderian gland def: "The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species[GO]. An accessory lacrimal gland on the inner side of the orbit in reptiles and birds but usually degenerate in mammals[BTO]." [GO:0070384, Wikipedia:Harderian_gland] synonym: "Harder's gland" RELATED [] synonym: "Hardarian gland" RELATED [] synonym: "gland of Hardarian" RELATED [] xref: EMAPA:19153 ! Harderian gland xref: GAID:1219 ! harderian gland xref: BTO:0000557 ! harderian gland xref: MA:0001247 ! harderian gland xref: MESH:A13.445 ! harderian gland is_a: UBERON:0001817 {source="BTO"} ! lacrimal gland relationship: part_of UBERON:0000019 ! camera-type eye relationship: never_in_taxon NCBITaxon:9606 ! Homo sapiens xref: ncithesaurus:Harderian_Gland ! Harderian Gland xref: SCTID:41474005 ! Harderian gland structure subset: organ_slim xref: UMLS:C0018597 [Term] id: UBERON:0003484 name: eye sebaceous gland def: "A sebaceous gland that is part of a camera-type eye [Automatically generated definition]." [OBOL:automatic] synonym: "camera-type eye sebaceous gland" EXACT [OBOL:automatic] synonym: "sebaceous gland of camera-type eye" EXACT [OBOL:automatic] synonym: "sebaceous gland of vertebrate eye" EXACT [OBOL:automatic] synonym: "vertebrate eye sebaceous gland" EXACT [OBOL:automatic] xref: MA:0002452 ! eye sebaceous gland is_a: UBERON:0003487 {source="MA"} ! skin sebaceous gland intersection_of: UBERON:0001821 ! sebaceous gland intersection_of: part_of UBERON:0000019 ! camera-type eye subset: organ_slim [Term] id: UBERON:0003485 name: vagina sebaceous gland def: "A sebaceous gland that is part of a vagina [Automatically generated definition]." [OBOL:automatic] synonym: "sebaceous gland of vagina" EXACT [OBOL:automatic] xref: MA:0001732 ! vagina sebaceous gland intersection_of: UBERON:0001821 ! sebaceous gland intersection_of: part_of UBERON:0000996 ! vagina subset: organ_slim [Term] id: UBERON:0003486 name: mammary gland sebaceous gland def: "A sebaceous gland that is part of a mammary gland [Automatically generated definition]." [OBOL:automatic] synonym: "lactiferous gland sebaceous gland" EXACT [OBOL:automatic] synonym: "lobe of breast sebaceous gland" EXACT [OBOL:automatic] synonym: "lobe of mammary gland sebaceous gland" EXACT [OBOL:automatic] synonym: "sebaceous gland of lactiferous gland" EXACT [OBOL:automatic] synonym: "sebaceous gland of lobe of breast" EXACT [OBOL:automatic] synonym: "sebaceous gland of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "sebaceous gland of mammary gland" EXACT [OBOL:automatic] xref: MA:0000794 ! mammary gland sebaceous gland intersection_of: UBERON:0001821 ! sebaceous gland intersection_of: part_of UBERON:0001911 ! lactiferous gland subset: organ_slim [Term] id: UBERON:0003489 name: respiratory system capillary endothelium def: "An endothelium of capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius capillary endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of capillary" EXACT [OBOL:automatic] synonym: "capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of capillary of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius blood capillary endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of capillary vessel" EXACT [OBOL:automatic] synonym: "blood capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood capillary endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "capillary vessel endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary vessel endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system blood capillary endothelium" EXACT [OBOL:automatic] synonym: "respiratory system capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of capillary vessel" EXACT [OBOL:automatic] xref: MA:0001808 ! respiratory system capillary endothelium intersection_of: UBERON:0001915 ! endothelium of capillary intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003526 {is_inferred="true", source="reference_0000032"} ! respiratory system capillary relationship: part_of UBERON:0003504 {source="reference_0000032"} ! respiratory system blood vessel [Term] id: UBERON:0003490 name: respiratory system reticular lamina def: "A reticular lamina that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius fibroreticular lamina" EXACT [OBOL:automatic] synonym: "apparatus respiratorius lamina fibroreticularis" EXACT [OBOL:automatic] synonym: "apparatus respiratorius reticular lamina" EXACT [OBOL:automatic] synonym: "fibroreticular lamina of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "fibroreticular lamina of respiratory system" EXACT [OBOL:automatic] synonym: "lamina fibroreticularis of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lamina fibroreticularis of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system fibroreticular lamina" EXACT [OBOL:automatic] synonym: "respiratory system lamina fibroreticularis" EXACT [OBOL:automatic] synonym: "reticular lamina of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "reticular lamina of respiratory system" EXACT [OBOL:automatic] xref: MA:0001817 ! respiratory system reticular lamina intersection_of: UBERON:0001967 ! reticular lamina intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003493 name: trachea reticular lamina def: "A reticular lamina that is part of a trachea [Automatically generated definition]." [OBOL:automatic] synonym: "fibroreticular lamina of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "fibroreticular lamina of windpipe" EXACT [OBOL:automatic] synonym: "lamina fibroreticularis of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "lamina fibroreticularis of windpipe" EXACT [OBOL:automatic] synonym: "reticular lamina of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "reticular lamina of windpipe" EXACT [OBOL:automatic] synonym: "windpipe fibroreticular lamina" EXACT [OBOL:automatic] synonym: "windpipe lamina fibroreticularis" EXACT [OBOL:automatic] synonym: "windpipe reticular lamina" EXACT [OBOL:automatic] xref: MA:0001856 ! trachea reticular lamina intersection_of: UBERON:0001967 ! reticular lamina intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0009653 {is_inferred="true", source="reference_0000032"} ! trachea basement membrane [Term] id: UBERON:0003492 name: bronchus reticular lamina def: "A reticular lamina that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi fibroreticular lamina" EXACT [OBOL:automatic] synonym: "bronchi lamina fibroreticularis" EXACT [OBOL:automatic] synonym: "bronchi reticular lamina" EXACT [OBOL:automatic] synonym: "bronchial trunk fibroreticular lamina" EXACT [OBOL:automatic] synonym: "bronchial trunk lamina fibroreticularis" EXACT [OBOL:automatic] synonym: "bronchial trunk reticular lamina" EXACT [OBOL:automatic] synonym: "bronchus fibroreticular lamina" EXACT [OBOL:automatic] synonym: "bronchus lamina fibroreticularis" EXACT [OBOL:automatic] synonym: "fibroreticular lamina of bronchi" EXACT [OBOL:automatic] synonym: "fibroreticular lamina of bronchial trunk" EXACT [OBOL:automatic] synonym: "fibroreticular lamina of bronchus" EXACT [OBOL:automatic] synonym: "lamina fibroreticularis of bronchi" EXACT [OBOL:automatic] synonym: "lamina fibroreticularis of bronchial trunk" EXACT [OBOL:automatic] synonym: "lamina fibroreticularis of bronchus" EXACT [OBOL:automatic] synonym: "reticular lamina of bronchi" EXACT [OBOL:automatic] synonym: "reticular lamina of bronchial trunk" EXACT [OBOL:automatic] synonym: "reticular lamina of bronchus" EXACT [OBOL:automatic] xref: MA:0001834 ! bronchus reticular lamina intersection_of: UBERON:0001967 ! reticular lamina intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0009652 {is_inferred="true", source="reference_0000032"} ! bronchus basement membrane [Term] id: UBERON:0003494 name: respiratory system venule def: "A venule that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius venule" EXACT [OBOL:automatic] synonym: "venule of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "venule of respiratory system" EXACT [OBOL:automatic] xref: MA:0001813 ! respiratory system venule intersection_of: UBERON:0001979 ! venule intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003495 name: respiratory system arteriole def: "An arteriole that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: MA:0001803 ! respiratory system arteriole intersection_of: UBERON:0001980 ! arteriole intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003469 {is_inferred="true", source="reference_0000032"} ! respiratory system artery [Term] id: UBERON:0003496 name: head blood vessel def: "A blood vessel that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of adult head" EXACT [OBOL:automatic] synonym: "blood vessel of head" EXACT [OBOL:automatic] xref: MA:0000575 ! head blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000033 ! head xref: SCTID:127865000 ! Entire blood vessel of head relationship: part_of UBERON:0011362 {is_inferred="true", source="reference_0000032"} ! cranial blood vasculature [Term] id: UBERON:0003497 name: abdomen blood vessel def: "A blood vessel that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] property_value: seeAlso "UBERON:0012254" xsd:string {notes="abdominal aorta artery"} synonym: "blood vessel of abdomen" EXACT [OBOL:automatic] xref: MA:0000518 ! abdomen blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0003498 name: heart blood vessel def: "A blood vessel that is part of a heart [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of heart" EXACT [OBOL:automatic] xref: MA:0002483 ! heart blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0003499 name: brain blood vessel def: "A blood vessel that is part of a brain [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of brain" EXACT [OBOL:automatic] xref: MA:0002769 ! brain blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000955 ! brain [Term] id: UBERON:0003500 name: corneal blood vessel def: "A blood vessel that is part of a cornea [Automatically generated definition]." [UBERON:cjm, https://sourceforge.net/tracker/index.php?func=detail&aid=3564332&group_id=36855&atid=440764] comment: Editor notes: follow up on tracker item synonym: "blood vessel of cornea" EXACT [OBOL:automatic] synonym: "cornea blood vessel" EXACT [OBOL:automatic] xref: MA:0001241 ! corneal blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000964 ! cornea relationship: present_in_taxon NCBITaxon:9775 {source="PMID:17051153"} ! Trichechidae [Term] id: UBERON:0003502 name: neck blood vessel def: "A blood vessel that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of neck" EXACT [OBOL:automatic] synonym: "blood vessel of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) blood vessel" EXACT [OBOL:automatic] xref: MA:0000583 ! neck blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003503 name: leg blood vessel def: "A blood vessel that is part of a leg [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of leg" EXACT [OBOL:automatic] xref: MA:0000669 ! leg blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000978 ! leg [Term] id: UBERON:0003504 name: respiratory system blood vessel def: "A blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood vessel of respiratory system" EXACT [OBOL:automatic] xref: MA:0001799 ! respiratory system blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003505 name: trachea blood vessel alt_id: UBERON:0003525 synonym: "blood vessel of trachea" EXACT [OBOL:automatic] xref: MA:0001852 ! trachea blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003126 ! trachea def: "A blood vessel that is part of a trachea." [OBOL:automatic] [Term] id: UBERON:0003506 name: chest blood vessel def: "A blood vessel that is part of a chest [Automatically generated definition]." [OBOL:automatic] synonym: "anterior thoracic region blood vessel" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of anterior thoracic region" EXACT [OBOL:automatic] synonym: "blood vessel of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "blood vessel of chest" EXACT [OBOL:automatic] synonym: "blood vessel of front of thorax" EXACT [OBOL:automatic] synonym: "front of thorax blood vessel" EXACT [OBOL:automatic] xref: MA:0000549 ! chest blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001443 ! chest [Term] id: UBERON:0003507 name: arm blood vessel def: "A blood vessel that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of arm" EXACT [OBOL:automatic] synonym: "blood vessel of brachial region" EXACT [OBOL:automatic] synonym: "blood vessel of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "brachial region blood vessel" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb blood vessel" EXACT [OBOL:automatic] xref: MA:0000591 ! arm blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001460 ! arm [Term] id: UBERON:0003508 name: pedal digit blood vessel def: "A blood vessel that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit blood vessel" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit blood vessel" EXACT [OBOL:accepted] synonym: "blood vessel of digit of foot" EXACT [OBOL:automatic] synonym: "blood vessel of digitus pedis" EXACT [OBOL:automatic] synonym: "blood vessel of foot digit" EXACT [OBOL:automatic] synonym: "blood vessel of toe" EXACT [OBOL:automatic] synonym: "digit of foot blood vessel" EXACT [OBOL:automatic] synonym: "digitus pedis blood vessel" EXACT [OBOL:automatic] synonym: "toe blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "blood vessel of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb blood vessel" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit blood vessel" EXACT [OBOL:automatic] xref: MA:0000645 ! foot digit blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001466 ! pedal digit synonym: "foot digit blood vessel" EXACT [MA:0000645] [Term] id: UBERON:0003510 name: eyelid blood vessel def: "A blood vessel that is part of a eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "blepharon blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of blepharon" EXACT [OBOL:automatic] synonym: "blood vessel of eyelid" EXACT [OBOL:automatic] xref: MA:0001250 ! eyelid blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001711 ! eyelid [Term] id: UBERON:0003511 name: iris blood vessel def: "A blood vessel that is part of a iris [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "blood vessel of iris" EXACT [OBOL:automatic] xref: MA:0001290 ! iris blood vessel xref: ZFA:0005568 ! iris blood vessels (also: UBERON:0004118 'vasculature of iris') intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001769 ! iris relationship: part_of UBERON:0004118 ! vasculature of iris [Term] id: UBERON:0003512 name: lung blood vessel def: "A blood vessel that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of lung" EXACT [OBOL:automatic] xref: MA:0002457 ! lung blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002048 ! lung [Term] id: UBERON:0003513 name: trunk blood vessel def: "A blood vessel that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of torso" EXACT [OBOL:automatic] synonym: "blood vessel of trunk" EXACT [OBOL:automatic] synonym: "torso blood vessel" EXACT [OBOL:automatic] xref: MA:0000511 ! trunk blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0003514 name: limb blood vessel def: "A blood vessel that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of limb" EXACT [OBOL:automatic] xref: MA:0000687 ! limb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0003515 name: forelimb blood vessel def: "A blood vessel that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing blood vessel" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "anteriormost limb blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of anteriormost limb" EXACT [OBOL:automatic] synonym: "blood vessel of fore limb" EXACT [OBOL:automatic] synonym: "blood vessel of forelimb" EXACT [OBOL:automatic] synonym: "blood vessel of superior member" EXACT [OBOL:automatic] synonym: "blood vessel of upper extremity" EXACT [OBOL:automatic] synonym: "fore limb blood vessel" EXACT [OBOL:automatic] synonym: "superior member blood vessel" EXACT [OBOL:automatic] synonym: "upper extremity blood vessel" EXACT [OBOL:automatic] xref: MA:0000611 ! forelimb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003516 name: hindlimb blood vessel def: "A blood vessel that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of hind limb" EXACT [OBOL:automatic] synonym: "blood vessel of hindlimb" EXACT [OBOL:automatic] synonym: "blood vessel of inferior member" EXACT [OBOL:automatic] synonym: "blood vessel of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb blood vessel" EXACT [OBOL:automatic] synonym: "inferior member blood vessel" EXACT [OBOL:automatic] synonym: "lower extremity blood vessel" EXACT [OBOL:automatic] xref: MA:0000659 ! hindlimb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003517 name: kidney blood vessel def: "A blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "blood vessel of kidney" EXACT [OBOL:automatic] synonym: "renal blood vessel" EXACT [OBOL:automatic] xref: MA:0001682 ! kidney blood vessel xref: ZFA:0005306 ! kidney blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0006544 ! kidney vasculature xref: TAO:0005306 ! kidney blood vessel [Term] id: UBERON:0006544 ! kidney vasculature name: kidney vasculature subset: vertebrate_core xref: ZFA:0005305 ! kidney vasculature xref: EMAPA:28457 ! renal vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002113 ! kidney xref: TAO:0005305 ! kidney vasculature def: "A vasculature that is part of a kidney." [OBOL:automatic] [Term] id: UBERON:0003518 name: main bronchus blood vessel def: "A blood vessel that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of bronchus principalis" EXACT [OBOL:automatic] synonym: "blood vessel of main bronchus" EXACT [OBOL:automatic] synonym: "blood vessel of primary bronchus" EXACT [OBOL:automatic] synonym: "blood vessel of principal bronchus" EXACT [OBOL:automatic] synonym: "bronchus principalis blood vessel" EXACT [OBOL:automatic] synonym: "primary bronchus blood vessel" EXACT [OBOL:automatic] synonym: "principal bronchus blood vessel" EXACT [OBOL:automatic] xref: MA:0001844 ! main bronchus blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002182 ! main bronchus [Term] id: UBERON:0003519 name: thoracic cavity blood vessel def: "A blood vessel that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of cavity of chest" EXACT [OBOL:automatic] synonym: "blood vessel of cavity of thorax" EXACT [OBOL:automatic] synonym: "blood vessel of chest cavity" EXACT [OBOL:automatic] synonym: "blood vessel of pectoral cavity" EXACT [OBOL:automatic] synonym: "blood vessel of thoracic cavity" EXACT [OBOL:automatic] synonym: "cavity of chest blood vessel" EXACT [OBOL:automatic] synonym: "cavity of thorax blood vessel" EXACT [OBOL:automatic] synonym: "chest cavity blood vessel" EXACT [OBOL:automatic] synonym: "pectoral cavity blood vessel" EXACT [OBOL:automatic] xref: MA:0000554 ! thoracic cavity blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003520 name: pelvis blood vessel def: "A blood vessel that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of pelvis" EXACT [OBOL:automatic] xref: MA:0000531 ! pelvis blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002355 ! pelvis [Term] id: UBERON:0003521 name: pes blood vessel def: "A blood vessel that is part of a foot [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of foot" EXACT [OBOL:automatic] synonym: "blood vessel of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb blood vessel" EXACT [OBOL:automatic] synonym: "autopod of hind limb blood vessel" EXACT [OBOL:automatic] synonym: "autopod of hindlimb blood vessel" EXACT [OBOL:automatic] synonym: "autopod of inferior member blood vessel" EXACT [OBOL:automatic] synonym: "autopod of lower extremity blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of autopod of hind limb" EXACT [OBOL:automatic] synonym: "blood vessel of autopod of hindlimb" EXACT [OBOL:automatic] synonym: "blood vessel of autopod of inferior member" EXACT [OBOL:automatic] synonym: "blood vessel of autopod of lower extremity" EXACT [OBOL:automatic] synonym: "blood vessel of distal free limb segment of hind limb" EXACT [OBOL:automatic] synonym: "blood vessel of distal free limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "blood vessel of distal free limb segment of inferior member" EXACT [OBOL:automatic] synonym: "blood vessel of distal free limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "blood vessel of hind limb autopod" EXACT [OBOL:automatic] synonym: "blood vessel of hind limb distal free limb segment" EXACT [OBOL:automatic] synonym: "blood vessel of hindlimb autopod" EXACT [OBOL:automatic] synonym: "blood vessel of hindlimb distal free limb segment" EXACT [OBOL:automatic] synonym: "blood vessel of inferior member autopod" EXACT [OBOL:automatic] synonym: "blood vessel of inferior member distal free limb segment" EXACT [OBOL:automatic] synonym: "blood vessel of lower extremity autopod" EXACT [OBOL:automatic] synonym: "blood vessel of lower extremity distal free limb segment" EXACT [OBOL:automatic] synonym: "distal free limb segment of hind limb blood vessel" EXACT [OBOL:automatic] synonym: "distal free limb segment of hindlimb blood vessel" EXACT [OBOL:automatic] synonym: "distal free limb segment of inferior member blood vessel" EXACT [OBOL:automatic] synonym: "distal free limb segment of lower extremity blood vessel" EXACT [OBOL:automatic] synonym: "hind limb autopod blood vessel" EXACT [OBOL:automatic] synonym: "hind limb distal free limb segment blood vessel" EXACT [OBOL:automatic] synonym: "hindlimb autopod blood vessel" EXACT [OBOL:automatic] synonym: "hindlimb distal free limb segment blood vessel" EXACT [OBOL:automatic] synonym: "inferior member autopod blood vessel" EXACT [OBOL:automatic] synonym: "inferior member distal free limb segment blood vessel" EXACT [OBOL:automatic] synonym: "lower extremity autopod blood vessel" EXACT [OBOL:automatic] synonym: "lower extremity distal free limb segment blood vessel" EXACT [OBOL:automatic] xref: MA:0000642 ! foot blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002387 ! pes synonym: "foot blood vessel" EXACT [MA:0000642] [Term] id: UBERON:0003522 name: manual digit blood vessel def: "A blood vessel that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit blood vessel" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit blood vessel" EXACT [OBOL:accepted] synonym: "blood vessel of digit of hand" EXACT [OBOL:automatic] synonym: "blood vessel of digitus manus" EXACT [OBOL:automatic] synonym: "blood vessel of finger" EXACT [OBOL:automatic] synonym: "blood vessel of hand digit" EXACT [OBOL:automatic] synonym: "digit of hand blood vessel" EXACT [OBOL:automatic] synonym: "digitus manus blood vessel" EXACT [OBOL:automatic] synonym: "finger blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "blood vessel of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb blood vessel" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit blood vessel" EXACT [OBOL:automatic] xref: MA:0000621 ! hand digit blood vessel synonym: "hand digit blood vessel" EXACT [MA:0000621] intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002389 ! manual digit [Term] id: UBERON:0003523 name: manus blood vessel def: "A blood vessel that is part of a manus [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of manus" EXACT [OBOL:automatic] synonym: "blood vessel of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb blood vessel" EXACT [OBOL:automatic] synonym: "arm autopod blood vessel" EXACT [OBOL:automatic] synonym: "arm distal free limb segment blood vessel" EXACT [OBOL:automatic] synonym: "autopod of arm blood vessel" EXACT [OBOL:automatic] synonym: "autopod of brachial region blood vessel" EXACT [OBOL:automatic] synonym: "autopod of proximal segment of free upper limb blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of arm autopod" EXACT [OBOL:automatic] synonym: "blood vessel of arm distal free limb segment" EXACT [OBOL:automatic] synonym: "blood vessel of autopod of arm" EXACT [OBOL:automatic] synonym: "blood vessel of autopod of brachial region" EXACT [OBOL:automatic] synonym: "blood vessel of autopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "blood vessel of brachial region autopod" EXACT [OBOL:automatic] synonym: "blood vessel of brachial region distal free limb segment" EXACT [OBOL:automatic] synonym: "blood vessel of distal free limb segment of arm" EXACT [OBOL:automatic] synonym: "blood vessel of distal free limb segment of brachial region" EXACT [OBOL:automatic] synonym: "blood vessel of distal free limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "blood vessel of proximal segment of free upper limb autopod" EXACT [OBOL:automatic] synonym: "blood vessel of proximal segment of free upper limb distal free limb segment" EXACT [OBOL:automatic] synonym: "brachial region autopod blood vessel" EXACT [OBOL:automatic] synonym: "brachial region distal free limb segment blood vessel" EXACT [OBOL:automatic] synonym: "distal free limb segment of arm blood vessel" EXACT [OBOL:automatic] synonym: "distal free limb segment of brachial region blood vessel" EXACT [OBOL:automatic] synonym: "distal free limb segment of proximal segment of free upper limb blood vessel" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb autopod blood vessel" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb distal free limb segment blood vessel" EXACT [OBOL:automatic] xref: MA:0000618 ! hand blood vessel synonym: "hand blood vessel" EXACT [MA:0000618] intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002398 ! manus [Term] id: UBERON:0003524 name: tail blood vessel def: "A blood vessel that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of post-vent region" EXACT [OBOL:automatic] synonym: "blood vessel of tail" EXACT [OBOL:automatic] synonym: "post-vent region blood vessel" EXACT [OBOL:automatic] xref: MA:0000695 ! tail blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0003526 name: respiratory system capillary def: "A capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary vessel" EXACT [OBOL:automatic] synonym: "blood capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood capillary of respiratory system" EXACT [OBOL:automatic] synonym: "capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary of respiratory system" EXACT [OBOL:automatic] synonym: "capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary vessel of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system blood capillary" EXACT [OBOL:automatic] synonym: "respiratory system capillary vessel" EXACT [OBOL:automatic] xref: MA:0001807 ! respiratory system capillary intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003527 name: kidney capillary def: "A capillary that is part of a kidney [Automatically generated definition]." [OBOL:automatic] synonym: "renal capillary" EXACT [OBOL:automatic] synonym: "blood capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary vessel of kidney" EXACT [OBOL:automatic] synonym: "kidney blood capillary" EXACT [OBOL:automatic] synonym: "kidney capillary vessel" EXACT [OBOL:automatic] xref: MA:0002586 ! kidney capillary xref: EMAPA:31443 ! renal capillaries intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0002113 ! kidney xref: SCTID:275409003 ! Entire capillary of kidney relationship: part_of UBERON:0006544 {source="reference_0000032"} ! kidney vasculature [Term] id: UBERON:0004212 name: glomerular capillary def: "A capillary that is part of a renal glomerulus [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "blood capillary of renal glomerulus" EXACT [OBOL:automatic] synonym: "capillary of renal glomerulus" EXACT [OBOL:automatic] synonym: "capillary vessel of renal glomerulus" EXACT [OBOL:automatic] synonym: "renal glomerulus blood capillary" EXACT [OBOL:automatic] synonym: "renal glomerulus capillary" EXACT [OBOL:automatic] synonym: "renal glomerulus capillary vessel" EXACT [OBOL:automatic] synonym: "glomerular capillary system" RELATED [MA:0002587] synonym: "glomerular capillaries" RELATED PLURAL [] xref: MA:0002587 ! glomerular capillary xref: ZFA:0005284 ! glomerular capillary xref: ncithesaurus:Glomerular_Capillary ! Glomerular Capillary xref: EMAPA:28245 ! glomerular capillary system xref: SCTID:362049007 ! Entire glomerular capillaries intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0000074 ! renal glomerulus xref: TAO:0005284 ! glomerular capillary property_value: external_definition "Capillary that is part of the renal glomerulus. Glomerular capillary endothelial membranes in zebrafish normally have a fenestrated morphology that is visible at the ultrastructural level.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005284", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-000824-1", source="ZFIN:curator"} relationship: part_of UBERON:0004190 {source="reference_0000032"} ! glomerulus vasculature xref: UMLS:C0226356 [Term] id: UBERON:0003528 name: brain grey matter def: "A gray matter of neuraxis that is part of a brain [Automatically generated definition]." [OBOL:automatic] synonym: "brain gray matter" EXACT [OBOL:automatic] synonym: "brain gray matter of neuraxis" EXACT [OBOL:automatic] synonym: "brain grey substance" EXACT [OBOL:automatic] synonym: "gray matter of brain" EXACT [OBOL:automatic] synonym: "gray matter of neuraxis of brain" EXACT [OBOL:automatic] synonym: "grey matter of brain" EXACT [OBOL:automatic] synonym: "grey substance of brain" EXACT [OBOL:automatic] xref: MA:0000810 ! brain grey matter xref: ncithesaurus:Cerebral_Gray_Matter ! Brain Gray Matter intersection_of: UBERON:0002020 ! gray matter of neuraxis intersection_of: part_of UBERON:0000955 ! brain xref: UMLS:C1707348 [Term] id: UBERON:0003529 name: respiratory system lymphatic vessel endothelium def: "An endothelium of lymphatic vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius endothelium of lymphatic vessel" EXACT [OBOL:automatic] synonym: "apparatus respiratorius lymphatic vessel endothelium" EXACT [OBOL:automatic] synonym: "endothelium of lymphatic vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of lymphatic vessel of respiratory system" EXACT [OBOL:automatic] synonym: "lymphatic vessel endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lymphatic vessel endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of lymphatic vessel" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of lymph vessel" EXACT [OBOL:automatic] synonym: "apparatus respiratorius lymph vessel endothelium" EXACT [OBOL:automatic] synonym: "endothelium of lymph vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of lymph vessel of respiratory system" EXACT [OBOL:automatic] synonym: "lymph vessel endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lymph vessel endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of lymph vessel" EXACT [OBOL:automatic] synonym: "respiratory system lymph vessel endothelium" EXACT [OBOL:automatic] xref: MA:0001825 ! respiratory system lymphatic vessel endothelium intersection_of: UBERON:0002042 ! endothelium of lymphatic vessel intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003456 ! respiratory system lymphatic vessel [Term] id: UBERON:0003530 name: pedal digit skin def: "A zone of skin that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit skin" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit skin" EXACT [OBOL:accepted] synonym: "digit of foot skin" EXACT [OBOL:automatic] synonym: "digitus pedis skin" EXACT [OBOL:automatic] synonym: "skin of digit of foot" EXACT [OBOL:automatic] synonym: "skin of digitus pedis" EXACT [OBOL:automatic] synonym: "skin of foot digit" EXACT [OBOL:automatic] synonym: "skin of toe" EXACT [OBOL:automatic] synonym: "toe skin" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb skin" EXACT [OBOL:automatic] synonym: "skin of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "skin of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit skin" EXACT [OBOL:automatic] xref: MA:0000650 ! foot digit skin xref: FMA:37852 ! Skin of toe xref: ncithesaurus:Foot_Digit_Skin ! Foot Digit Skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001466 ! pedal digit xref: SCTID:181530005 ! Entire skin of toe synonym: "foot digit skin" EXACT [MA:0000650] xref: UMLS:C1708089 [Term] id: UBERON:0003531 name: forelimb skin def: "A zone of skin that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing skin" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] comment: TODO - check free limb vs pectoral complex synonym: "anteriormost limb skin" EXACT [OBOL:automatic] synonym: "fore limb skin" EXACT [OBOL:automatic] synonym: "skin of anteriormost limb" EXACT [OBOL:automatic] synonym: "skin of fore limb" EXACT [OBOL:automatic] synonym: "skin of forelimb" EXACT [OBOL:automatic] synonym: "skin of superior member" EXACT [OBOL:automatic] synonym: "skin of upper extremity" EXACT [OBOL:automatic] synonym: "superior member skin" EXACT [OBOL:automatic] synonym: "upper extremity skin" EXACT [OBOL:automatic] synonym: "skin of upper limb" EXACT [FMA:23101] synonym: "upper limb skin" EXACT [FMA:23101] xref: MA:0000617 ! forelimb skin xref: FMA:23101 ! Skin of upper limb intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002102 ! forelimb xref: SCTID:244130001 ! Entire skin of upper extremity xref: ncithesaurus:Skin_of_the_Upper_Limb_and_Shoulder ! skin of the upper limb and shoulder xref: UMLS:C0222212 [Term] id: UBERON:0003532 name: hindlimb skin def: "A zone of skin that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] comment: TODO - check free limb vs pelvic complex synonym: "hind limb skin" EXACT [OBOL:automatic] synonym: "inferior member skin" EXACT [OBOL:automatic] synonym: "lower extremity skin" EXACT [OBOL:automatic] synonym: "skin of hind limb" EXACT [OBOL:automatic] synonym: "skin of hindlimb" EXACT [OBOL:automatic] synonym: "skin of inferior member" EXACT [OBOL:automatic] synonym: "skin of lower extremity" EXACT [OBOL:automatic] synonym: "skin of lower limb" EXACT [FMA:23102] synonym: "lower limb skin" EXACT [FMA:23102] xref: MA:0000665 ! hindlimb skin xref: FMA:23102 ! Skin of lower limb intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002103 ! hindlimb xref: SCTID:181528008 ! Entire skin of lower extremity xref: ncithesaurus:Skin_of_the_Lower_Limb_and_Hip ! skin of the lower limb and hip xref: UMLS:C0222268 [Term] id: UBERON:0003533 name: manual digit skin def: "A zone of skin that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit skin" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit skin" EXACT [OBOL:accepted] synonym: "digit of hand skin" EXACT [OBOL:automatic] synonym: "digitus manus skin" EXACT [OBOL:automatic] synonym: "finger skin" EXACT [OBOL:automatic] synonym: "skin of digit of hand" EXACT [OBOL:automatic] synonym: "skin of digitus manus" EXACT [OBOL:automatic] synonym: "skin of finger" EXACT [OBOL:automatic] synonym: "skin of hand digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb skin" EXACT [OBOL:automatic] synonym: "skin of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "skin of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit skin" EXACT [OBOL:automatic] xref: MA:0000626 ! hand digit skin synonym: "hand digit skin" EXACT [MA:0000626] xref: FMA:38304 ! Skin of finger xref: ncithesaurus:Hand_Digit_Skin ! Hand Digit Skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002389 ! manual digit xref: SCTID:361711001 ! Entire skin of finger xref: UMLS:C1708318 [Term] id: UBERON:0003534 name: tail skin def: "A zone of skin that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "post-vent region skin" EXACT [OBOL:automatic] synonym: "skin of post-vent region" EXACT [OBOL:automatic] synonym: "skin of tail" EXACT [OBOL:automatic] xref: MA:0000700 ! tail skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0007812 ! post-anal tail xref: SCTID:67214004 ! Skin of tail [Term] id: UBERON:0003535 name: vagus X nerve trunk xref: MA:0001150 ! vagus X nerve trunk xref: FMA:6221 ! Trunk of vagus nerve intersection_of: UBERON:0002464 ! nerve trunk intersection_of: part_of UBERON:0001759 ! vagus nerve xref: SCTID:280308004 ! Trunk of vagus nerve synonym: "trunk of vagus nerve" EXACT [FMA:6221] synonym: "vagus neural trunk" EXACT [FMA:6221] def: "A nerve trunk that is part of a vagus nerve." [OBOL:automatic] [Term] id: UBERON:0003540 name: right lung terminal bronchiole def: "A terminal bronchiole that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus terminalis of right lung" EXACT [OBOL:automatic] synonym: "right lung bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "terminal bronchiole of right lung" EXACT [OBOL:automatic] xref: MA:0001789 ! right lung terminal bronchiole xref: ncithesaurus:Right_Lung_Terminal_Bronchiole ! Right Lung Terminal Bronchiole intersection_of: UBERON:0002187 ! terminal bronchiole intersection_of: part_of UBERON:0002167 ! right lung xref: UMLS:C1709961 [Term] id: UBERON:0003541 name: left lung terminal bronchiole def: "A terminal bronchiole that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus terminalis of left lung" EXACT [OBOL:automatic] synonym: "left lung bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "terminal bronchiole of left lung" EXACT [OBOL:automatic] xref: MA:0001780 ! left lung terminal bronchiole xref: ncithesaurus:Left_Lung_Terminal_Bronchiole ! Left Lung Terminal Bronchiole intersection_of: UBERON:0002187 ! terminal bronchiole intersection_of: part_of UBERON:0002168 ! left lung xref: UMLS:C1708675 [Term] id: UBERON:0003542 name: right lung respiratory bronchiole def: "A respiratory bronchiole that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus respiratorius of right lung" EXACT [OBOL:automatic] synonym: "respiratory bronchiole of right lung" EXACT [OBOL:automatic] synonym: "right lung bronchiolus respiratorius" EXACT [OBOL:automatic] xref: MA:0001788 ! right lung respiratory bronchiole xref: ncithesaurus:Right_Lung_Respiratory_Bronchiole ! Right Lung Respiratory Bronchiole intersection_of: UBERON:0002188 ! respiratory bronchiole intersection_of: part_of UBERON:0002167 ! right lung xref: UMLS:C1709960 [Term] id: UBERON:0003543 name: left lung respiratory bronchiole def: "A respiratory bronchiole that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus respiratorius of left lung" EXACT [OBOL:automatic] synonym: "left lung bronchiolus respiratorius" EXACT [OBOL:automatic] synonym: "respiratory bronchiole of left lung" EXACT [OBOL:automatic] xref: MA:0001779 ! left lung respiratory bronchiole xref: ncithesaurus:Left_Lung_Respiratory_Bronchiole ! Left Lung Respiratory Bronchiole intersection_of: UBERON:0002188 ! respiratory bronchiole intersection_of: part_of UBERON:0002168 ! left lung xref: UMLS:C1708674 [Term] id: UBERON:0003544 name: brain white matter def: "the regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites." [MP:0008026] synonym: "brain white matter of neuraxis" EXACT [OBOL:automatic] synonym: "brain white substance" EXACT [OBOL:automatic] synonym: "white matter of brain" EXACT [OBOL:automatic] synonym: "white matter of neuraxis of brain" EXACT [OBOL:automatic] synonym: "white substance of brain" EXACT [OBOL:automatic] xref: MA:0000820 ! brain white matter xref: ncithesaurus:Brain_White_Matter ! Brain White Matter intersection_of: UBERON:0002316 ! white matter of neuraxis intersection_of: part_of UBERON:0000955 ! brain xref: UMLS:C1706995 [Term] id: UBERON:0003545 name: obsolete brainstem white matter comment: obsoleted as definition is unclear. cerebellar peduncle originally classified here but in ABA brainstem and cerbellum are spatially disjoint consider: MA:0002741 ! brainstem white matter is_obsolete: true [Term] id: UBERON:0003547 name: brain meninx def: "A meninx that is part of a brain [Automatically generated definition]." [OBOL:automatic] synonym: "brain meninges" EXACT [OBOL:automatic] synonym: "meninges of brain" EXACT [OBOL:automatic] synonym: "meninx of brain" EXACT [OBOL:automatic] xref: MA:0000813 ! brain meninges xref: VHOG:0000013 ! brain meninges xref: EV:0100312 ! meninges (also: UBERON:0002360 'meninx') intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0000955 ! brain subset: organ_slim xref: SCTID:180949007 ! Region of brain meninges property_value: external_definition "Meninges that are part of the brain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000013", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000013", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003548 name: forebrain meninges def: "A meninx that is part of a forebrain [Automatically generated definition]." [OBOL:automatic] synonym: "forebrain meninx" EXACT [OBOL:automatic] synonym: "meninges of forebrain" EXACT [OBOL:automatic] synonym: "meninx of forebrain" EXACT [OBOL:automatic] xref: MA:0000883 ! forebrain meninges xref: EMAPA:17764 ! meninges of diencephalon of forebrain (also: UBERON:0003290 'meninx of diencephalon') xref: EMAPA:17774 ! meninges of telencephalon of forebrain (also: UBERON:0003289 'meninx of telencephalon') intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0001890 ! forebrain [Term] id: UBERON:0003549 name: brain pia mater def: "the fibrous membrane forming the innermost of the three coverings that surrounds the brain within the cranial cavity that is firmly attached to the glial capsule." [MP:0009026] synonym: "brain pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "pia mater of brain" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of brain" EXACT [OBOL:automatic] xref: MA:0000816 ! brain pia mater xref: ncithesaurus:Brain_Pia_Mater ! Brain Pia Mater xref: VHOG:0000470 ! brain pia mater xref: EV:0100315 ! pia mater (also: UBERON:0002361 'pia mater') intersection_of: UBERON:0002361 ! pia mater intersection_of: part_of UBERON:0000955 ! brain property_value: external_definition "The innermost of the three mammalian meninges covering the brain and spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000470", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/pia+mater", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000470", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1706994 [Term] id: UBERON:0003550 name: forebrain pia mater def: "A pia mater that is part of a forebrain [Automatically generated definition]." [OBOL:automatic] synonym: "forebrain pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "pia mater of forebrain" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of forebrain" EXACT [OBOL:automatic] xref: MA:0000886 ! forebrain pia mater xref: EMAPA:17767 ! pia mater of meninges of diencephalon of forebrain (also: UBERON:0003553 'diencephalon pia mater') xref: EMAPA:17777 ! pia mater of meninges of telencephalon of forebrain (also: UBERON:0003552 'telencephalon pia mater') intersection_of: UBERON:0002361 ! pia mater intersection_of: part_of UBERON:0001890 ! forebrain [Term] id: UBERON:0003551 name: midbrain pia mater def: "A pia mater that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "midbrain pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "pia mater of midbrain" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of midbrain" EXACT [OBOL:automatic] xref: MA:0001061 ! midbrain pia mater xref: VHOG:0000467 ! midbrain pia mater xref: EHDAA2:0001175 ! midbrain pia mater xref: RETIRED_EHDAA2:0001110 ! mesencephalon pia mater xref: EMAPA:17794 ! pia mater of meninges of midbrain intersection_of: UBERON:0002361 ! pia mater intersection_of: part_of UBERON:0001891 ! midbrain synonym: "mesencephalon pia mater" RELATED [VHOG:0000467] property_value: external_definition "Pia mater that is part of the midbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000467", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000467", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003552 name: telencephalon pia mater def: "A pia mater that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "pia mater of neuraxis of telencephalon" EXACT [OBOL:automatic] synonym: "pia mater of telencephalon" EXACT [OBOL:automatic] synonym: "telencephalon pia mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000982 ! telencephalon pia mater xref: VHOG:0000476 ! telencephalon pia mater xref: EHDAA2:0001992 ! telencephalon pia mater xref: EMAPA:17777 ! pia mater of meninges of telencephalon of forebrain (also: UBERON:0003550 'forebrain pia mater') intersection_of: UBERON:0002361 ! pia mater intersection_of: part_of UBERON:0001893 ! telencephalon property_value: external_definition "Pia mater that is part of the telencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000476", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000476", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003553 name: diencephalon pia mater def: "A pia mater that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "between brain pia mater" EXACT [OBOL:automatic] synonym: "between brain pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "diencephalon pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "interbrain pia mater" EXACT [OBOL:automatic] synonym: "interbrain pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "mature diencephalon pia mater" EXACT [OBOL:automatic] synonym: "mature diencephalon pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "pia mater of between brain" EXACT [OBOL:automatic] synonym: "pia mater of diencephalon" EXACT [OBOL:automatic] synonym: "pia mater of interbrain" EXACT [OBOL:automatic] synonym: "pia mater of mature diencephalon" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of between brain" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of diencephalon" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of interbrain" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of mature diencephalon" EXACT [OBOL:automatic] xref: MA:0000829 ! diencephalon pia mater xref: VHOG:0000475 ! diencephalon pia mater xref: EHDAA2:0000400 ! diencephalon pia mater xref: EMAPA:17767 ! pia mater of meninges of diencephalon of forebrain (also: UBERON:0003550 'forebrain pia mater') intersection_of: UBERON:0002361 ! pia mater intersection_of: part_of UBERON:0001894 ! diencephalon property_value: external_definition "Pia mater that is part of the diencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000475", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000475", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003554 name: hindbrain pia mater def: "A pia mater that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] synonym: "hindbrain pia mater of neuraxis" EXACT [OBOL:automatic] synonym: "pia mater of hindbrain" EXACT [OBOL:automatic] synonym: "pia mater of neuraxis of hindbrain" EXACT [OBOL:automatic] xref: MA:0000990 ! hindbrain pia mater xref: VHOG:0000466 ! hindbrain pia mater xref: EHDAA2:0000772 ! hindbrain pia mater xref: EMAPA:17786 ! pia mater of meninges of hindbrain of brain of central nervous system of nervous system of organ system intersection_of: UBERON:0002361 ! pia mater intersection_of: part_of UBERON:0002028 ! hindbrain synonym: "rhombencephalon pia mater" RELATED [VHOG:0000466] property_value: external_definition "Pia mater that is part of the hindbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000466", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000466", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003555 name: spinal cord pia mater def: "A pia mater that is part of a spinal cord [Automatically generated definition]." [OBOL:automatic] synonym: "pia mater of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "pia mater of spinal cord" EXACT [OBOL:automatic] synonym: "spinal cord pia mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0001133 ! spinal cord pia mater xref: ncithesaurus:Spinal_Cord_Pia_Mater ! Spinal Cord Pia Mater xref: VHOG:0000468 ! spinal cord pia mater xref: EHDAA2:0001896 ! spinal cord pia mater xref: EMAPA:17807 ! pia mater of meninges of spinal cord of central nervous system of nervous system of organ system intersection_of: UBERON:0002361 ! pia mater intersection_of: part_of UBERON:0002240 ! spinal cord subset: organ_slim property_value: external_definition "The innermost of the three mammalian meninges covering the brain and spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000468", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/pia+mater", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000468", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1710148 [Term] id: UBERON:0003556 name: forebrain arachnoid mater def: "An arachnoid mater that is part of a forebrain [Automatically generated definition]." [OBOL:automatic] synonym: "arachnoid mater of forebrain" EXACT [OBOL:automatic] synonym: "arachnoid mater of neuraxis of forebrain" EXACT [OBOL:automatic] synonym: "arachnoid of forebrain" EXACT [OBOL:automatic] synonym: "forebrain arachnoid" EXACT [OBOL:automatic] synonym: "forebrain arachnoid mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000884 ! forebrain arachnoid mater xref: EMAPA:17765 ! arachnoid mater of meninges of diencephalon of forebrain (also: UBERON:0003558 'diencephalon arachnoid mater') xref: EMAPA:17775 ! arachnoid mater of meninges of telencephalon of forebrain (also: UBERON:0005400 'telencephalon arachnoid mater') intersection_of: UBERON:0002362 ! arachnoid mater intersection_of: part_of UBERON:0001890 ! forebrain [Term] id: UBERON:0005400 name: telencephalon arachnoid mater synonym: "telencephalon arachnoid matter" EXACT [MA:0000980] xref: MA:0000980 ! telencephalon arachnoid matter xref: EMAPA:17775 ! arachnoid mater of meninges of telencephalon of forebrain (also: UBERON:0003556 'forebrain arachnoid mater') intersection_of: UBERON:0002362 ! arachnoid mater intersection_of: part_of UBERON:0001893 ! telencephalon def: "An arachnoid mater that is part of a telencephalon." [OBOL:automatic] [Term] id: UBERON:0003557 name: midbrain arachnoid mater def: "An arachnoid mater that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "arachnoid mater of midbrain" EXACT [OBOL:automatic] synonym: "arachnoid mater of neuraxis of midbrain" EXACT [OBOL:automatic] synonym: "arachnoid of midbrain" EXACT [OBOL:automatic] synonym: "midbrain arachnoid" EXACT [OBOL:automatic] synonym: "midbrain arachnoid mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0001059 ! midbrain arachnoid mater xref: VHOG:0000233 ! midbrain arachnoid mater xref: EMAPA:17792 ! arachnoid mater of meninges of midbrain intersection_of: UBERON:0002362 ! arachnoid mater intersection_of: part_of UBERON:0001891 ! midbrain synonym: "mesencephalon arachnoid mater" RELATED [VHOG:0000233] property_value: external_definition "Arachnoid mater that is part of the midbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000233", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000233", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003558 name: diencephalon arachnoid mater def: "An arachnoid mater that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "arachnoid mater of between brain" EXACT [OBOL:automatic] synonym: "arachnoid mater of diencephalon" EXACT [OBOL:automatic] synonym: "arachnoid mater of interbrain" EXACT [OBOL:automatic] synonym: "arachnoid mater of mature diencephalon" EXACT [OBOL:automatic] synonym: "arachnoid mater of neuraxis of between brain" EXACT [OBOL:automatic] synonym: "arachnoid mater of neuraxis of diencephalon" EXACT [OBOL:automatic] synonym: "arachnoid mater of neuraxis of interbrain" EXACT [OBOL:automatic] synonym: "arachnoid mater of neuraxis of mature diencephalon" EXACT [OBOL:automatic] synonym: "arachnoid of between brain" EXACT [OBOL:automatic] synonym: "arachnoid of diencephalon" EXACT [OBOL:automatic] synonym: "arachnoid of interbrain" EXACT [OBOL:automatic] synonym: "arachnoid of mature diencephalon" EXACT [OBOL:automatic] synonym: "between brain arachnoid" EXACT [OBOL:automatic] synonym: "between brain arachnoid mater" EXACT [OBOL:automatic] synonym: "between brain arachnoid mater of neuraxis" EXACT [OBOL:automatic] synonym: "diencephalon arachnoid" EXACT [OBOL:automatic] synonym: "diencephalon arachnoid mater of neuraxis" EXACT [OBOL:automatic] synonym: "interbrain arachnoid" EXACT [OBOL:automatic] synonym: "interbrain arachnoid mater" EXACT [OBOL:automatic] synonym: "interbrain arachnoid mater of neuraxis" EXACT [OBOL:automatic] synonym: "mature diencephalon arachnoid" EXACT [OBOL:automatic] synonym: "mature diencephalon arachnoid mater" EXACT [OBOL:automatic] synonym: "mature diencephalon arachnoid mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000827 ! diencephalon arachnoid mater xref: VHOG:0000231 ! diencephalon arachnoid mater xref: EMAPA:17765 ! arachnoid mater of meninges of diencephalon of forebrain (also: UBERON:0003556 'forebrain arachnoid mater') intersection_of: UBERON:0002362 ! arachnoid mater intersection_of: part_of UBERON:0001894 ! diencephalon property_value: external_definition "Arachnoid mater that is part of the diencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000231", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000231", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003559 name: hindbrain arachnoid mater def: "An arachnoid mater that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] synonym: "arachnoid mater of hindbrain" EXACT [OBOL:automatic] synonym: "arachnoid mater of neuraxis of hindbrain" EXACT [OBOL:automatic] synonym: "arachnoid of hindbrain" EXACT [OBOL:automatic] synonym: "hindbrain arachnoid" EXACT [OBOL:automatic] synonym: "hindbrain arachnoid mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000988 ! hindbrain arachnoid mater xref: VHOG:0000236 ! hindbrain arachnoid mater xref: EMAPA:17784 ! arachnoid mater of meninges of hindbrain of brain of central nervous system of nervous system of organ system intersection_of: UBERON:0002362 ! arachnoid mater intersection_of: part_of UBERON:0002028 ! hindbrain synonym: "rhombencephalon arachnoid mater" RELATED [VHOG:0000236] property_value: external_definition "Arachnoid mater that is part of the hindbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000236", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000236", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003560 name: spinal cord arachnoid mater def: "An arachnoid mater that is part of a spinal cord [Automatically generated definition]." [OBOL:automatic] synonym: "arachnoid mater of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "arachnoid mater of spinal cord" EXACT [OBOL:automatic] synonym: "arachnoid of spinal cord" EXACT [OBOL:automatic] synonym: "spinal cord arachnoid" EXACT [OBOL:automatic] synonym: "spinal cord arachnoid mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0001131 ! spinal cord arachnoid mater xref: VHOG:0000234 ! spinal cord arachnoid mater xref: EMAPA:17805 ! arachnoid mater of meninges of spinal cord of central nervous system of nervous system of organ system intersection_of: UBERON:0002362 ! arachnoid mater intersection_of: part_of UBERON:0002240 ! spinal cord subset: organ_slim property_value: external_definition "The middle membrane of the three mammalian meninges covering the brain and spinal cord. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000234", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/arachnoid+mater", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000234", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003561 name: forebrain dura mater synonym: "dura mater of forebrain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of forebrain" EXACT [OBOL:automatic] synonym: "forebrain dura mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000885 ! forebrain dura mater xref: EMAPA:17766 ! dura mater of meninges of diencephalon of forebrain (also: UBERON:0002092 'brain dura mater') (also: UBERON:0003564 'diencephalon dura mater') intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0001890 ! forebrain def: "A dura mater that is part of a forebrain." [OBOL:automatic] [Term] id: UBERON:0003562 name: midbrain dura mater def: "A dura mater that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "dura mater of midbrain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of midbrain" EXACT [OBOL:automatic] synonym: "midbrain dura mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0001060 ! midbrain dura mater xref: VHOG:0000410 ! midbrain dura mater xref: EMAPA:17793 ! dura mater of meninges of midbrain (also: UBERON:0002092 'brain dura mater') intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0001891 ! midbrain synonym: "mesencephalon dura mater" RELATED [VHOG:0000410] property_value: external_definition "Dura mater that is part of the midbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000410", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000410", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003563 name: telencephalon dura mater def: "A dura mater that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "dura mater of neuraxis of telencephalon" EXACT [OBOL:automatic] synonym: "dura mater of telencephalon" EXACT [OBOL:automatic] synonym: "telencephalon dura mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000981 ! telencephalon dura mater intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0001893 ! telencephalon [Term] id: UBERON:0003564 name: diencephalon dura mater def: "A dura mater that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "between brain dura mater" EXACT [OBOL:automatic] synonym: "between brain dura mater of neuraxis" EXACT [OBOL:automatic] synonym: "diencephalon dura mater of neuraxis" EXACT [OBOL:automatic] synonym: "dura mater of between brain" EXACT [OBOL:automatic] synonym: "dura mater of diencephalon" EXACT [OBOL:automatic] synonym: "dura mater of interbrain" EXACT [OBOL:automatic] synonym: "dura mater of mature diencephalon" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of between brain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of diencephalon" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of interbrain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of mature diencephalon" EXACT [OBOL:automatic] synonym: "interbrain dura mater" EXACT [OBOL:automatic] synonym: "interbrain dura mater of neuraxis" EXACT [OBOL:automatic] synonym: "mature diencephalon dura mater" EXACT [OBOL:automatic] synonym: "mature diencephalon dura mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000828 ! diencephalon dura mater xref: VHOG:0000258 ! diencephalon dura mater xref: EMAPA:17766 ! dura mater of meninges of diencephalon of forebrain (also: UBERON:0002092 'brain dura mater') (also: UBERON:0003561 'forebrain dura mater') intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0001894 ! diencephalon property_value: external_definition "Dura mater that is part of the diencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000258", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000258", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003565 name: hindbrain dura mater def: "A dura mater that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] synonym: "dura mater of hindbrain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of hindbrain" EXACT [OBOL:automatic] synonym: "hindbrain dura mater of neuraxis" EXACT [OBOL:automatic] xref: MA:0000989 ! hindbrain dura mater xref: VHOG:0000409 ! hindbrain dura mater xref: EMAPA:17785 ! dura mater of meninges of hindbrain of brain of central nervous system of nervous system of organ system (also: UBERON:0002092 'brain dura mater') intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0002028 ! hindbrain synonym: "rhombencephalon dura mater" RELATED [VHOG:0000409] property_value: external_definition "Dura mater that is part of the hindbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000409", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000409", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0003566 name: head connective tissue def: "A portion of connective tissue that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head connective tissue" EXACT [OBOL:automatic] synonym: "adult head portion of connective tissue" EXACT [OBOL:automatic] synonym: "adult head textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of adult head" EXACT [OBOL:automatic] synonym: "connective tissue of head" EXACT [OBOL:automatic] synonym: "head portion of connective tissue" EXACT [OBOL:automatic] synonym: "head textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of adult head" EXACT [OBOL:automatic] synonym: "portion of connective tissue of head" EXACT [OBOL:automatic] synonym: "textus connectivus of adult head" EXACT [OBOL:automatic] synonym: "textus connectivus of head" EXACT [OBOL:automatic] xref: MA:0000577 ! head connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000033 ! head [Term] id: UBERON:0003567 name: abdomen connective tissue def: "A portion of connective tissue that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "abdomen portion of connective tissue" EXACT [OBOL:automatic] synonym: "abdomen textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of abdomen" EXACT [OBOL:automatic] synonym: "portion of connective tissue of abdomen" EXACT [OBOL:automatic] synonym: "textus connectivus of abdomen" EXACT [OBOL:automatic] xref: MA:0000519 ! abdomen connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0003568 name: neck connective tissue def: "A portion of connective tissue that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of neck" EXACT [OBOL:automatic] synonym: "connective tissue of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) connective tissue" EXACT [OBOL:automatic] synonym: "neck (volume) portion of connective tissue" EXACT [OBOL:automatic] synonym: "neck (volume) textus connectivus" EXACT [OBOL:automatic] synonym: "neck portion of connective tissue" EXACT [OBOL:automatic] synonym: "neck textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of neck" EXACT [OBOL:automatic] synonym: "portion of connective tissue of neck (volume)" EXACT [OBOL:automatic] synonym: "textus connectivus of neck" EXACT [OBOL:automatic] synonym: "textus connectivus of neck (volume)" EXACT [OBOL:automatic] xref: MA:0000585 ! neck connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003569 name: leg connective tissue def: "A portion of connective tissue that is part of a leg [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of leg" EXACT [OBOL:automatic] synonym: "leg portion of connective tissue" EXACT [OBOL:automatic] synonym: "leg textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of leg" EXACT [OBOL:automatic] synonym: "textus connectivus of leg" EXACT [OBOL:automatic] xref: MA:0000671 ! leg connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000978 ! leg [Term] id: UBERON:0003570 name: respiratory system connective tissue def: "A portion of connective tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius portion of connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "portion of connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "portion of connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system portion of connective tissue" EXACT [OBOL:automatic] synonym: "respiratory system textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "textus connectivus of respiratory system" EXACT [OBOL:automatic] xref: MA:0001814 ! respiratory system connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003571 name: trachea connective tissue synonym: "connective tissue of trachea" EXACT [OBOL:automatic] synonym: "connective tissue of windpipe" EXACT [OBOL:automatic] synonym: "portion of connective tissue of trachea" EXACT [OBOL:automatic] synonym: "portion of connective tissue of windpipe" EXACT [OBOL:automatic] synonym: "textus connectivus of trachea" EXACT [OBOL:automatic] synonym: "textus connectivus of windpipe" EXACT [OBOL:automatic] synonym: "trachea portion of connective tissue" EXACT [OBOL:automatic] synonym: "trachea textus connectivus" EXACT [OBOL:automatic] synonym: "windpipe connective tissue" EXACT [OBOL:automatic] synonym: "windpipe portion of connective tissue" EXACT [OBOL:automatic] synonym: "windpipe textus connectivus" EXACT [OBOL:automatic] xref: MA:0001853 ! trachea connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0003126 ! trachea def: "A connective tissue that is part of a trachea." [OBOL:automatic] [Term] id: UBERON:0003572 name: chest connective tissue def: "A portion of connective tissue that is part of a chest [Automatically generated definition]." [OBOL:automatic] synonym: "anterior thoracic region connective tissue" EXACT [OBOL:automatic] synonym: "anterior thoracic region portion of connective tissue" EXACT [OBOL:automatic] synonym: "anterior thoracic region textus connectivus" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax connective tissue" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "anterolateral part of thorax textus connectivus" EXACT [OBOL:automatic] synonym: "chest portion of connective tissue" EXACT [OBOL:automatic] synonym: "chest textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of anterior thoracic region" EXACT [OBOL:automatic] synonym: "connective tissue of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "connective tissue of chest" EXACT [OBOL:automatic] synonym: "connective tissue of front of thorax" EXACT [OBOL:automatic] synonym: "front of thorax connective tissue" EXACT [OBOL:automatic] synonym: "front of thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "front of thorax textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of anterior thoracic region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "portion of connective tissue of chest" EXACT [OBOL:automatic] synonym: "portion of connective tissue of front of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of anterior thoracic region" EXACT [OBOL:automatic] synonym: "textus connectivus of anterolateral part of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of chest" EXACT [OBOL:automatic] synonym: "textus connectivus of front of thorax" EXACT [OBOL:automatic] xref: MA:0000550 ! chest connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001443 ! chest [Term] id: UBERON:0003573 name: arm connective tissue def: "A portion of connective tissue that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "arm textus connectivus" EXACT [OBOL:automatic] synonym: "brachial region connective tissue" EXACT [OBOL:automatic] synonym: "brachial region portion of connective tissue" EXACT [OBOL:automatic] synonym: "brachial region textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of arm" EXACT [OBOL:automatic] synonym: "connective tissue of brachial region" EXACT [OBOL:automatic] synonym: "connective tissue of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of brachial region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of arm" EXACT [OBOL:automatic] synonym: "textus connectivus of brachial region" EXACT [OBOL:automatic] synonym: "textus connectivus of proximal segment of free upper limb" EXACT [OBOL:automatic] xref: MA:0000593 ! arm connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001460 ! arm [Term] id: UBERON:0003574 name: elbow connective tissue def: "A portion of connective tissue that is part of a elbow [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of cubital region" EXACT [OBOL:automatic] synonym: "connective tissue of elbow" EXACT [OBOL:automatic] synonym: "cubital region connective tissue" EXACT [OBOL:automatic] synonym: "cubital region portion of connective tissue" EXACT [OBOL:automatic] synonym: "cubital region textus connectivus" EXACT [OBOL:automatic] synonym: "elbow portion of connective tissue" EXACT [OBOL:automatic] synonym: "elbow textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of cubital region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of elbow" EXACT [OBOL:automatic] synonym: "textus connectivus of cubital region" EXACT [OBOL:automatic] synonym: "textus connectivus of elbow" EXACT [OBOL:automatic] xref: MA:0000609 ! elbow connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001461 ! elbow [Term] id: UBERON:0003575 name: wrist connective tissue def: "A portion of connective tissue that is part of a wrist [Automatically generated definition]." [OBOL:automatic] synonym: "carpal region connective tissue" EXACT [OBOL:automatic] synonym: "carpal region portion of connective tissue" EXACT [OBOL:automatic] synonym: "carpal region textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of carpal region" EXACT [OBOL:automatic] synonym: "connective tissue of wrist" EXACT [OBOL:automatic] synonym: "portion of connective tissue of carpal region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of wrist" EXACT [OBOL:automatic] synonym: "textus connectivus of carpal region" EXACT [OBOL:automatic] synonym: "textus connectivus of wrist" EXACT [OBOL:automatic] synonym: "wrist portion of connective tissue" EXACT [OBOL:automatic] synonym: "wrist textus connectivus" EXACT [OBOL:automatic] xref: MA:0000636 ! wrist connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0003576 name: hip connective tissue def: "A portion of connective tissue that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of hip" EXACT [OBOL:automatic] synonym: "connective tissue of hip region" EXACT [OBOL:automatic] synonym: "connective tissue of regio coxae" EXACT [OBOL:automatic] synonym: "hip portion of connective tissue" EXACT [OBOL:automatic] synonym: "hip region connective tissue" EXACT [OBOL:automatic] synonym: "hip region portion of connective tissue" EXACT [OBOL:automatic] synonym: "hip region textus connectivus" EXACT [OBOL:automatic] synonym: "hip textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hip" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hip region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of regio coxae" EXACT [OBOL:automatic] synonym: "regio coxae connective tissue" EXACT [OBOL:automatic] synonym: "regio coxae portion of connective tissue" EXACT [OBOL:automatic] synonym: "regio coxae textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of hip" EXACT [OBOL:automatic] synonym: "textus connectivus of hip region" EXACT [OBOL:automatic] synonym: "textus connectivus of regio coxae" EXACT [OBOL:automatic] xref: MA:0000656 ! hip connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001464 ! hip [Term] id: UBERON:0003577 name: knee connective tissue def: "A portion of connective tissue that is part of a knee [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of knee" EXACT [OBOL:automatic] synonym: "knee portion of connective tissue" EXACT [OBOL:automatic] synonym: "knee textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of knee" EXACT [OBOL:automatic] synonym: "textus connectivus of knee" EXACT [OBOL:automatic] xref: MA:0000667 ! knee connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001465 ! knee [Term] id: UBERON:0003578 name: pedal digit connective tissue def: "A portion of connective tissue that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit connective tissue" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit connective tissue" EXACT [OBOL:accepted] synonym: "connective tissue of digit of foot" EXACT [OBOL:automatic] synonym: "connective tissue of digitus pedis" EXACT [OBOL:automatic] synonym: "connective tissue of foot digit" EXACT [OBOL:automatic] synonym: "connective tissue of toe" EXACT [OBOL:automatic] synonym: "digit of foot connective tissue" EXACT [OBOL:automatic] synonym: "digit of foot portion of connective tissue" EXACT [OBOL:automatic] synonym: "digit of foot textus connectivus" EXACT [OBOL:automatic] synonym: "digitus pedis connective tissue" EXACT [OBOL:automatic] synonym: "digitus pedis portion of connective tissue" EXACT [OBOL:automatic] synonym: "digitus pedis textus connectivus" EXACT [OBOL:automatic] synonym: "foot digit portion of connective tissue" EXACT [OBOL:automatic] synonym: "foot digit textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of digit of foot" EXACT [OBOL:automatic] synonym: "portion of connective tissue of digitus pedis" EXACT [OBOL:automatic] synonym: "portion of connective tissue of foot digit" EXACT [OBOL:automatic] synonym: "portion of connective tissue of toe" EXACT [OBOL:automatic] synonym: "textus connectivus of digit of foot" EXACT [OBOL:automatic] synonym: "textus connectivus of digitus pedis" EXACT [OBOL:automatic] synonym: "textus connectivus of foot digit" EXACT [OBOL:automatic] synonym: "textus connectivus of toe" EXACT [OBOL:automatic] synonym: "toe connective tissue" EXACT [OBOL:automatic] synonym: "toe portion of connective tissue" EXACT [OBOL:automatic] synonym: "toe textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "connective tissue of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb connective tissue" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit portion of connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "textus connectivus of terminal segment of free lower limb digit" EXACT [OBOL:automatic] xref: MA:0000647 ! foot digit connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001466 ! pedal digit synonym: "foot digit connective tissue" EXACT [MA:0000647] [Term] id: UBERON:0003579 name: shoulder connective tissue def: "A portion of connective tissue that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of shoulder" EXACT [OBOL:automatic] synonym: "portion of connective tissue of shoulder" EXACT [OBOL:automatic] synonym: "shoulder portion of connective tissue" EXACT [OBOL:automatic] synonym: "shoulder textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of shoulder" EXACT [OBOL:automatic] xref: MA:0000632 ! shoulder connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001467 ! shoulder [Term] id: UBERON:0003580 name: lower respiratory tract connective tissue def: "A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower respiratory tract textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "textus connectivus of lower respiratory tract" EXACT [OBOL:automatic] xref: MA:0002409 ! lower respiratory tract connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001558 ! lower respiratory tract [Term] id: UBERON:0003582 name: nasopharynx connective tissue def: "A portion of connective tissue that is part of a nasopharynx [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "connective tissue of nasopharynx" EXACT [OBOL:automatic] synonym: "connective tissue of rhinopharynx" EXACT [OBOL:automatic] synonym: "nasal part of pharynx connective tissue" EXACT [OBOL:automatic] synonym: "nasal part of pharynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "nasal part of pharynx textus connectivus" EXACT [OBOL:automatic] synonym: "nasopharynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "nasopharynx textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "portion of connective tissue of nasopharynx" EXACT [OBOL:automatic] synonym: "portion of connective tissue of rhinopharynx" EXACT [OBOL:automatic] synonym: "rhinopharynx connective tissue" EXACT [OBOL:automatic] synonym: "rhinopharynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "rhinopharynx textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "textus connectivus of nasopharynx" EXACT [OBOL:automatic] synonym: "textus connectivus of rhinopharynx" EXACT [OBOL:automatic] xref: MA:0001864 ! nasopharynx connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001728 ! nasopharynx [Term] id: UBERON:0003583 name: larynx connective tissue def: "A portion of connective tissue that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of larynx" EXACT [OBOL:automatic] synonym: "larynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "larynx textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of larynx" EXACT [OBOL:automatic] synonym: "textus connectivus of larynx" EXACT [OBOL:automatic] xref: MA:0001754 ! larynx connective tissue xref: ncithesaurus:Laryngeal_Connective_Tissue ! Laryngeal Connective Tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001737 ! larynx xref: UMLS:C1708651 [Term] id: UBERON:0003584 name: mammary gland connective tissue def: "the fibrous supportive tissue of the mammary gland." [MP:0009507] synonym: "connective tissue of lactiferous gland" EXACT [OBOL:automatic] synonym: "connective tissue of lobe of breast" EXACT [OBOL:automatic] synonym: "connective tissue of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "connective tissue of mammary gland" EXACT [OBOL:automatic] synonym: "lactiferous gland connective tissue" EXACT [OBOL:automatic] synonym: "lactiferous gland portion of connective tissue" EXACT [OBOL:automatic] synonym: "lactiferous gland textus connectivus" EXACT [OBOL:automatic] synonym: "lobe of breast connective tissue" EXACT [OBOL:automatic] synonym: "lobe of breast portion of connective tissue" EXACT [OBOL:automatic] synonym: "lobe of breast textus connectivus" EXACT [OBOL:automatic] synonym: "lobe of mammary gland connective tissue" EXACT [OBOL:automatic] synonym: "lobe of mammary gland portion of connective tissue" EXACT [OBOL:automatic] synonym: "lobe of mammary gland textus connectivus" EXACT [OBOL:automatic] synonym: "mammary gland portion of connective tissue" EXACT [OBOL:automatic] synonym: "mammary gland textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lactiferous gland" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lobe of breast" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "portion of connective tissue of mammary gland" EXACT [OBOL:automatic] synonym: "textus connectivus of lactiferous gland" EXACT [OBOL:automatic] synonym: "textus connectivus of lobe of breast" EXACT [OBOL:automatic] synonym: "textus connectivus of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "textus connectivus of mammary gland" EXACT [OBOL:automatic] xref: MA:0002897 ! mammary gland connective tissue xref: FMA:74479 ! Connective tissue of lactiferous gland intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001911 ! lactiferous gland [Term] id: UBERON:0003585 name: dermis connective tissue def: "A portion of connective tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of dermis" EXACT [OBOL:automatic] synonym: "dermis portion of connective tissue" EXACT [OBOL:automatic] synonym: "dermis textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of dermis" EXACT [OBOL:automatic] synonym: "textus connectivus of dermis" EXACT [OBOL:automatic] xref: MA:0000799 ! dermis connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002067 ! dermis relationship: develops_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest [Term] id: UBERON:0003586 name: trunk connective tissue def: "A portion of connective tissue that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of torso" EXACT [OBOL:automatic] synonym: "connective tissue of trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of torso" EXACT [OBOL:automatic] synonym: "portion of connective tissue of trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of torso" EXACT [OBOL:automatic] synonym: "textus connectivus of trunk" EXACT [OBOL:automatic] synonym: "torso connective tissue" EXACT [OBOL:automatic] synonym: "torso portion of connective tissue" EXACT [OBOL:automatic] synonym: "torso textus connectivus" EXACT [OBOL:automatic] synonym: "trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "trunk textus connectivus" EXACT [OBOL:automatic] xref: MA:0000513 ! trunk connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0003587 name: limb connective tissue def: "A portion of connective tissue that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of limb" EXACT [OBOL:automatic] synonym: "limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "limb textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of limb" EXACT [OBOL:automatic] synonym: "textus connectivus of limb" EXACT [OBOL:automatic] xref: MA:0000689 ! limb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0003588 name: forelimb connective tissue def: "A portion of connective tissue that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing connective tissue" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "anteriormost limb connective tissue" EXACT [OBOL:automatic] synonym: "anteriormost limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "anteriormost limb textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of anteriormost limb" EXACT [OBOL:automatic] synonym: "connective tissue of fore limb" EXACT [OBOL:automatic] synonym: "connective tissue of forelimb" EXACT [OBOL:automatic] synonym: "connective tissue of superior member" EXACT [OBOL:automatic] synonym: "connective tissue of upper extremity" EXACT [OBOL:automatic] synonym: "fore limb connective tissue" EXACT [OBOL:automatic] synonym: "fore limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "fore limb textus connectivus" EXACT [OBOL:automatic] synonym: "forelimb portion of connective tissue" EXACT [OBOL:automatic] synonym: "forelimb textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of anteriormost limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of fore limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of forelimb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of superior member" EXACT [OBOL:automatic] synonym: "portion of connective tissue of upper extremity" EXACT [OBOL:automatic] synonym: "superior member connective tissue" EXACT [OBOL:automatic] synonym: "superior member portion of connective tissue" EXACT [OBOL:automatic] synonym: "superior member textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of anteriormost limb" EXACT [OBOL:automatic] synonym: "textus connectivus of fore limb" EXACT [OBOL:automatic] synonym: "textus connectivus of forelimb" EXACT [OBOL:automatic] synonym: "textus connectivus of superior member" EXACT [OBOL:automatic] synonym: "textus connectivus of upper extremity" EXACT [OBOL:automatic] synonym: "upper extremity connective tissue" EXACT [OBOL:automatic] synonym: "upper extremity portion of connective tissue" EXACT [OBOL:automatic] synonym: "upper extremity textus connectivus" EXACT [OBOL:automatic] xref: MA:0000613 ! forelimb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003589 name: hindlimb connective tissue def: "A portion of connective tissue that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of hind limb" EXACT [OBOL:automatic] synonym: "connective tissue of hindlimb" EXACT [OBOL:automatic] synonym: "connective tissue of inferior member" EXACT [OBOL:automatic] synonym: "connective tissue of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb connective tissue" EXACT [OBOL:automatic] synonym: "hind limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "hind limb textus connectivus" EXACT [OBOL:automatic] synonym: "hindlimb portion of connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb textus connectivus" EXACT [OBOL:automatic] synonym: "inferior member connective tissue" EXACT [OBOL:automatic] synonym: "inferior member portion of connective tissue" EXACT [OBOL:automatic] synonym: "inferior member textus connectivus" EXACT [OBOL:automatic] synonym: "lower extremity connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hind limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hindlimb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of inferior member" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower extremity" EXACT [OBOL:automatic] synonym: "textus connectivus of hind limb" EXACT [OBOL:automatic] synonym: "textus connectivus of hindlimb" EXACT [OBOL:automatic] synonym: "textus connectivus of inferior member" EXACT [OBOL:automatic] synonym: "textus connectivus of lower extremity" EXACT [OBOL:automatic] xref: MA:0000661 ! hindlimb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003590 name: main bronchus connective tissue def: "A portion of connective tissue that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchus principalis connective tissue" EXACT [OBOL:automatic] synonym: "bronchus principalis portion of connective tissue" EXACT [OBOL:automatic] synonym: "bronchus principalis textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of bronchus principalis" EXACT [OBOL:automatic] synonym: "connective tissue of main bronchus" EXACT [OBOL:automatic] synonym: "connective tissue of primary bronchus" EXACT [OBOL:automatic] synonym: "connective tissue of principal bronchus" EXACT [OBOL:automatic] synonym: "main bronchus portion of connective tissue" EXACT [OBOL:automatic] synonym: "main bronchus textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of bronchus principalis" EXACT [OBOL:automatic] synonym: "portion of connective tissue of main bronchus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of primary bronchus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of principal bronchus" EXACT [OBOL:automatic] synonym: "primary bronchus connective tissue" EXACT [OBOL:automatic] synonym: "primary bronchus portion of connective tissue" EXACT [OBOL:automatic] synonym: "primary bronchus textus connectivus" EXACT [OBOL:automatic] synonym: "principal bronchus connective tissue" EXACT [OBOL:automatic] synonym: "principal bronchus portion of connective tissue" EXACT [OBOL:automatic] synonym: "principal bronchus textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of bronchus principalis" EXACT [OBOL:automatic] synonym: "textus connectivus of main bronchus" EXACT [OBOL:automatic] synonym: "textus connectivus of primary bronchus" EXACT [OBOL:automatic] synonym: "textus connectivus of principal bronchus" EXACT [OBOL:automatic] xref: MA:0001845 ! main bronchus connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002182 ! main bronchus [Term] id: UBERON:0003591 name: lobar bronchus connective tissue def: "A portion of connective tissue that is part of a lobar bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of lobar bronchus" EXACT [OBOL:automatic] synonym: "connective tissue of secondary bronchus" EXACT [OBOL:automatic] synonym: "lobar bronchus portion of connective tissue" EXACT [OBOL:automatic] synonym: "lobar bronchus textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lobar bronchus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of secondary bronchus" EXACT [OBOL:automatic] synonym: "secondary bronchus connective tissue" EXACT [OBOL:automatic] synonym: "secondary bronchus portion of connective tissue" EXACT [OBOL:automatic] synonym: "secondary bronchus textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of lobar bronchus" EXACT [OBOL:automatic] synonym: "textus connectivus of secondary bronchus" EXACT [OBOL:automatic] xref: MA:0001841 ! lobar bronchus connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002183 ! lobar bronchus [Term] id: UBERON:0003592 name: bronchus connective tissue def: "A portion of connective tissue that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi connective tissue" EXACT [OBOL:automatic] synonym: "bronchi portion of connective tissue" EXACT [OBOL:automatic] synonym: "bronchi textus connectivus" EXACT [OBOL:automatic] synonym: "bronchial trunk connective tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk textus connectivus" EXACT [OBOL:automatic] synonym: "bronchus portion of connective tissue" EXACT [OBOL:automatic] synonym: "bronchus textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of bronchi" EXACT [OBOL:automatic] synonym: "connective tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "connective tissue of bronchus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of bronchi" EXACT [OBOL:automatic] synonym: "portion of connective tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of bronchus" EXACT [OBOL:automatic] synonym: "textus connectivus of bronchi" EXACT [OBOL:automatic] synonym: "textus connectivus of bronchial trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of bronchus" EXACT [OBOL:automatic] xref: MA:0001831 ! bronchus connective tissue xref: ncithesaurus:Bronchus_Connective_Tissue ! Bronchus Connective Tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002185 ! bronchus xref: UMLS:C1707052 [Term] id: UBERON:0003593 name: thoracic cavity connective tissue def: "A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest connective tissue" EXACT [OBOL:automatic] synonym: "cavity of chest portion of connective tissue" EXACT [OBOL:automatic] synonym: "cavity of chest textus connectivus" EXACT [OBOL:automatic] synonym: "cavity of thorax connective tissue" EXACT [OBOL:automatic] synonym: "cavity of thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "cavity of thorax textus connectivus" EXACT [OBOL:automatic] synonym: "chest cavity connective tissue" EXACT [OBOL:automatic] synonym: "chest cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "chest cavity textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of cavity of chest" EXACT [OBOL:automatic] synonym: "connective tissue of cavity of thorax" EXACT [OBOL:automatic] synonym: "connective tissue of chest cavity" EXACT [OBOL:automatic] synonym: "connective tissue of pectoral cavity" EXACT [OBOL:automatic] synonym: "connective tissue of thoracic cavity" EXACT [OBOL:automatic] synonym: "pectoral cavity connective tissue" EXACT [OBOL:automatic] synonym: "pectoral cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "pectoral cavity textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of cavity of chest" EXACT [OBOL:automatic] synonym: "portion of connective tissue of cavity of thorax" EXACT [OBOL:automatic] synonym: "portion of connective tissue of chest cavity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of pectoral cavity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of thoracic cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of cavity of chest" EXACT [OBOL:automatic] synonym: "textus connectivus of cavity of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of chest cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of pectoral cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of thoracic cavity" EXACT [OBOL:automatic] synonym: "thoracic cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "thoracic cavity textus connectivus" EXACT [OBOL:automatic] xref: MA:0000555 ! thoracic cavity connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003594 name: pelvis connective tissue def: "A portion of connective tissue that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of pelvis" EXACT [OBOL:automatic] synonym: "pelvis portion of connective tissue" EXACT [OBOL:automatic] synonym: "pelvis textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of pelvis" EXACT [OBOL:automatic] synonym: "textus connectivus of pelvis" EXACT [OBOL:automatic] xref: MA:0000533 ! pelvis connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002355 ! pelvis [Term] id: UBERON:0003595 name: pes connective tissue def: "A portion of connective tissue that is part of a foot [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of foot" EXACT [OBOL:automatic] synonym: "connective tissue of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "foot portion of connective tissue" EXACT [OBOL:automatic] synonym: "foot textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of foot" EXACT [OBOL:automatic] synonym: "portion of connective tissue of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of foot" EXACT [OBOL:automatic] synonym: "textus connectivus of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "autopod of hind limb connective tissue" EXACT [OBOL:automatic] synonym: "autopod of hind limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "autopod of hind limb textus connectivus" EXACT [OBOL:automatic] synonym: "autopod of hindlimb connective tissue" EXACT [OBOL:automatic] synonym: "autopod of hindlimb portion of connective tissue" EXACT [OBOL:automatic] synonym: "autopod of hindlimb textus connectivus" EXACT [OBOL:automatic] synonym: "autopod of inferior member connective tissue" EXACT [OBOL:automatic] synonym: "autopod of inferior member portion of connective tissue" EXACT [OBOL:automatic] synonym: "autopod of inferior member textus connectivus" EXACT [OBOL:automatic] synonym: "autopod of lower extremity connective tissue" EXACT [OBOL:automatic] synonym: "autopod of lower extremity portion of connective tissue" EXACT [OBOL:automatic] synonym: "autopod of lower extremity textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of autopod of hind limb" EXACT [OBOL:automatic] synonym: "connective tissue of autopod of hindlimb" EXACT [OBOL:automatic] synonym: "connective tissue of autopod of inferior member" EXACT [OBOL:automatic] synonym: "connective tissue of autopod of lower extremity" EXACT [OBOL:automatic] synonym: "connective tissue of distal free limb segment of hind limb" EXACT [OBOL:automatic] synonym: "connective tissue of distal free limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "connective tissue of distal free limb segment of inferior member" EXACT [OBOL:automatic] synonym: "connective tissue of distal free limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "connective tissue of hind limb autopod" EXACT [OBOL:automatic] synonym: "connective tissue of hind limb distal free limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of hindlimb autopod" EXACT [OBOL:automatic] synonym: "connective tissue of hindlimb distal free limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of inferior member autopod" EXACT [OBOL:automatic] synonym: "connective tissue of inferior member distal free limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of lower extremity autopod" EXACT [OBOL:automatic] synonym: "connective tissue of lower extremity distal free limb segment" EXACT [OBOL:automatic] synonym: "distal free limb segment of hind limb connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of hind limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of hind limb textus connectivus" EXACT [OBOL:automatic] synonym: "distal free limb segment of hindlimb connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of hindlimb portion of connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of hindlimb textus connectivus" EXACT [OBOL:automatic] synonym: "distal free limb segment of inferior member connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of inferior member portion of connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of inferior member textus connectivus" EXACT [OBOL:automatic] synonym: "distal free limb segment of lower extremity connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of lower extremity portion of connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of lower extremity textus connectivus" EXACT [OBOL:automatic] synonym: "hind limb autopod connective tissue" EXACT [OBOL:automatic] synonym: "hind limb autopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "hind limb autopod textus connectivus" EXACT [OBOL:automatic] synonym: "hind limb distal free limb segment connective tissue" EXACT [OBOL:automatic] synonym: "hind limb distal free limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "hind limb distal free limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "hindlimb autopod connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb autopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb autopod textus connectivus" EXACT [OBOL:automatic] synonym: "hindlimb distal free limb segment connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb distal free limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb distal free limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "inferior member autopod connective tissue" EXACT [OBOL:automatic] synonym: "inferior member autopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "inferior member autopod textus connectivus" EXACT [OBOL:automatic] synonym: "inferior member distal free limb segment connective tissue" EXACT [OBOL:automatic] synonym: "inferior member distal free limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "inferior member distal free limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "lower extremity autopod connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity autopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity autopod textus connectivus" EXACT [OBOL:automatic] synonym: "lower extremity distal free limb segment connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity distal free limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity distal free limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of autopod of hind limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of autopod of hindlimb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of autopod of inferior member" EXACT [OBOL:automatic] synonym: "portion of connective tissue of autopod of lower extremity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of distal free limb segment of hind limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of distal free limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of distal free limb segment of inferior member" EXACT [OBOL:automatic] synonym: "portion of connective tissue of distal free limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hind limb autopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hind limb distal free limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hindlimb autopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hindlimb distal free limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of inferior member autopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of inferior member distal free limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower extremity autopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower extremity distal free limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of autopod of hind limb" EXACT [OBOL:automatic] synonym: "textus connectivus of autopod of hindlimb" EXACT [OBOL:automatic] synonym: "textus connectivus of autopod of inferior member" EXACT [OBOL:automatic] synonym: "textus connectivus of autopod of lower extremity" EXACT [OBOL:automatic] synonym: "textus connectivus of distal free limb segment of hind limb" EXACT [OBOL:automatic] synonym: "textus connectivus of distal free limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "textus connectivus of distal free limb segment of inferior member" EXACT [OBOL:automatic] synonym: "textus connectivus of distal free limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "textus connectivus of hind limb autopod" EXACT [OBOL:automatic] synonym: "textus connectivus of hind limb distal free limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of hindlimb autopod" EXACT [OBOL:automatic] synonym: "textus connectivus of hindlimb distal free limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of inferior member autopod" EXACT [OBOL:automatic] synonym: "textus connectivus of inferior member distal free limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of lower extremity autopod" EXACT [OBOL:automatic] synonym: "textus connectivus of lower extremity distal free limb segment" EXACT [OBOL:automatic] xref: MA:0000644 ! foot connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002387 ! pes synonym: "foot connective tissue" EXACT [MA:0000644] [Term] id: UBERON:0003596 name: ankle connective tissue def: "A portion of connective tissue that is part of an ankle [Automatically generated definition]." [OBOL:automatic] synonym: "tarsal region connective tissue" EXACT [UBERON:cjm] synonym: "ankle portion of connective tissue" EXACT [OBOL:automatic] synonym: "ankle textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of ankle" EXACT [OBOL:automatic] synonym: "portion of connective tissue of ankle" EXACT [OBOL:automatic] synonym: "textus connectivus of ankle" EXACT [OBOL:automatic] xref: MA:0000639 ! ankle connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0004454 ! tarsal region [Term] id: UBERON:0003597 name: manual digit connective tissue def: "A portion of connective tissue that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit connective tissue" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit connective tissue" EXACT [OBOL:accepted] synonym: "connective tissue of digit of hand" EXACT [OBOL:automatic] synonym: "connective tissue of digitus manus" EXACT [OBOL:automatic] synonym: "connective tissue of finger" EXACT [OBOL:automatic] synonym: "connective tissue of hand digit" EXACT [OBOL:automatic] synonym: "digit of hand connective tissue" EXACT [OBOL:automatic] synonym: "digit of hand portion of connective tissue" EXACT [OBOL:automatic] synonym: "digit of hand textus connectivus" EXACT [OBOL:automatic] synonym: "digitus manus connective tissue" EXACT [OBOL:automatic] synonym: "digitus manus portion of connective tissue" EXACT [OBOL:automatic] synonym: "digitus manus textus connectivus" EXACT [OBOL:automatic] synonym: "finger connective tissue" EXACT [OBOL:automatic] synonym: "finger portion of connective tissue" EXACT [OBOL:automatic] synonym: "finger textus connectivus" EXACT [OBOL:automatic] synonym: "hand digit portion of connective tissue" EXACT [OBOL:automatic] synonym: "hand digit textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of digit of hand" EXACT [OBOL:automatic] synonym: "portion of connective tissue of digitus manus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of finger" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hand digit" EXACT [OBOL:automatic] synonym: "textus connectivus of digit of hand" EXACT [OBOL:automatic] synonym: "textus connectivus of digitus manus" EXACT [OBOL:automatic] synonym: "textus connectivus of finger" EXACT [OBOL:automatic] synonym: "textus connectivus of hand digit" EXACT [OBOL:automatic] synonym: "connective tissue of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "connective tissue of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit portion of connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "textus connectivus of terminal segment of free upper limb digit" EXACT [OBOL:automatic] xref: MA:0000623 ! hand digit connective tissue synonym: "hand digit connective tissue" EXACT [MA:0000623] intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002389 ! hand digit [Term] id: UBERON:0003598 name: manus connective tissue def: "A portion of connective tissue that is part of a hand [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of hand" EXACT [OBOL:automatic] synonym: "connective tissue of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "hand portion of connective tissue" EXACT [OBOL:automatic] synonym: "hand textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hand" EXACT [OBOL:automatic] synonym: "portion of connective tissue of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of hand" EXACT [OBOL:automatic] synonym: "textus connectivus of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "arm autopod connective tissue" EXACT [OBOL:automatic] synonym: "arm autopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "arm autopod textus connectivus" EXACT [OBOL:automatic] synonym: "arm distal free limb segment connective tissue" EXACT [OBOL:automatic] synonym: "arm distal free limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "arm distal free limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "autopod of arm connective tissue" EXACT [OBOL:automatic] synonym: "autopod of arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "autopod of arm textus connectivus" EXACT [OBOL:automatic] synonym: "autopod of brachial region connective tissue" EXACT [OBOL:automatic] synonym: "autopod of brachial region portion of connective tissue" EXACT [OBOL:automatic] synonym: "autopod of brachial region textus connectivus" EXACT [OBOL:automatic] synonym: "autopod of proximal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "autopod of proximal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "autopod of proximal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "brachial region autopod connective tissue" EXACT [OBOL:automatic] synonym: "brachial region autopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "brachial region autopod textus connectivus" EXACT [OBOL:automatic] synonym: "brachial region distal free limb segment connective tissue" EXACT [OBOL:automatic] synonym: "brachial region distal free limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "brachial region distal free limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of arm autopod" EXACT [OBOL:automatic] synonym: "connective tissue of arm distal free limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of autopod of arm" EXACT [OBOL:automatic] synonym: "connective tissue of autopod of brachial region" EXACT [OBOL:automatic] synonym: "connective tissue of autopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "connective tissue of brachial region autopod" EXACT [OBOL:automatic] synonym: "connective tissue of brachial region distal free limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of distal free limb segment of arm" EXACT [OBOL:automatic] synonym: "connective tissue of distal free limb segment of brachial region" EXACT [OBOL:automatic] synonym: "connective tissue of distal free limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "connective tissue of proximal segment of free upper limb autopod" EXACT [OBOL:automatic] synonym: "connective tissue of proximal segment of free upper limb distal free limb segment" EXACT [OBOL:automatic] synonym: "distal free limb segment of arm connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of arm textus connectivus" EXACT [OBOL:automatic] synonym: "distal free limb segment of brachial region connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of brachial region portion of connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of brachial region textus connectivus" EXACT [OBOL:automatic] synonym: "distal free limb segment of proximal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of proximal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "distal free limb segment of proximal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of arm autopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of arm distal free limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of autopod of arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of autopod of brachial region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of autopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of brachial region autopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of brachial region distal free limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of distal free limb segment of arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of distal free limb segment of brachial region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of distal free limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of proximal segment of free upper limb autopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of proximal segment of free upper limb distal free limb segment" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb autopod connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb autopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb autopod textus connectivus" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb distal free limb segment connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb distal free limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb distal free limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of arm autopod" EXACT [OBOL:automatic] synonym: "textus connectivus of arm distal free limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of autopod of arm" EXACT [OBOL:automatic] synonym: "textus connectivus of autopod of brachial region" EXACT [OBOL:automatic] synonym: "textus connectivus of autopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "textus connectivus of brachial region autopod" EXACT [OBOL:automatic] synonym: "textus connectivus of brachial region distal free limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of distal free limb segment of arm" EXACT [OBOL:automatic] synonym: "textus connectivus of distal free limb segment of brachial region" EXACT [OBOL:automatic] synonym: "textus connectivus of distal free limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "textus connectivus of proximal segment of free upper limb autopod" EXACT [OBOL:automatic] synonym: "textus connectivus of proximal segment of free upper limb distal free limb segment" EXACT [OBOL:automatic] xref: MA:0000620 ! hand connective tissue synonym: "hand connective tissue" EXACT [MA:0000620] intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002398 ! hand [Term] id: UBERON:0003599 name: tail connective tissue def: "A portion of connective tissue that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of post-vent region" EXACT [OBOL:automatic] synonym: "connective tissue of tail" EXACT [OBOL:automatic] synonym: "portion of connective tissue of post-vent region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of tail" EXACT [OBOL:automatic] synonym: "post-vent region connective tissue" EXACT [OBOL:automatic] synonym: "post-vent region portion of connective tissue" EXACT [OBOL:automatic] synonym: "post-vent region textus connectivus" EXACT [OBOL:automatic] synonym: "tail portion of connective tissue" EXACT [OBOL:automatic] synonym: "tail textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of post-vent region" EXACT [OBOL:automatic] synonym: "textus connectivus of tail" EXACT [OBOL:automatic] xref: MA:0000697 ! tail connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0003601 name: neck cartilage def: "A cartilage that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "cartilage of neck" EXACT [OBOL:automatic] synonym: "cartilage of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) cartilage" EXACT [OBOL:automatic] xref: MA:0000586 ! neck cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003603 name: lower respiratory tract cartilage def: "A cartilage that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "cartilage of lower respiratory tract" EXACT [OBOL:automatic] xref: MA:0001819 ! lower respiratory tract cartilage xref: ncithesaurus:Lower_Respiratory_Tract_Cartilage ! Lower Respiratory Tract Cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0001558 ! lower respiratory tract xref: UMLS:C1708759 [Term] id: UBERON:0003605 name: eye skin gland def: "A skin gland that is part of a camera-type eye [Automatically generated definition]." [OBOL:automatic] synonym: "camera-type eye skin gland" EXACT [OBOL:automatic] synonym: "camera-type eye skin glands" EXACT [OBOL:automatic] synonym: "camera-type eye skin glands set" EXACT [OBOL:automatic] synonym: "skin gland of camera-type eye" EXACT [OBOL:automatic] synonym: "skin gland of vertebrate eye" EXACT [OBOL:automatic] synonym: "skin glands of camera-type eye" EXACT [OBOL:automatic] synonym: "skin glands of vertebrate eye" EXACT [OBOL:automatic] synonym: "skin glands set of camera-type eye" EXACT [OBOL:automatic] synonym: "skin glands set of vertebrate eye" EXACT [OBOL:automatic] synonym: "vertebrate eye skin gland" EXACT [OBOL:automatic] synonym: "vertebrate eye skin glands" EXACT [OBOL:automatic] synonym: "vertebrate eye skin glands set" EXACT [OBOL:automatic] xref: MA:0002451 ! eye skin gland intersection_of: UBERON:0002419 ! skin gland intersection_of: part_of UBERON:0000019 ! camera-type eye subset: organ_slim [Term] id: UBERON:0003606 name: limb long bone def: "A long bone that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "long bone of limb" EXACT [OBOL:automatic] xref: MA:0000298 ! limb long bone intersection_of: UBERON:0002495 ! long bone intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0003607 name: forelimb long bone def: "A long bone that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing long bone" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "anteriormost limb long bone" EXACT [OBOL:automatic] synonym: "fore limb long bone" EXACT [OBOL:automatic] synonym: "long bone of anteriormost limb" EXACT [OBOL:automatic] synonym: "long bone of fore limb" EXACT [OBOL:automatic] synonym: "long bone of forelimb" EXACT [OBOL:automatic] synonym: "long bone of superior member" EXACT [OBOL:automatic] synonym: "long bone of upper extremity" EXACT [OBOL:automatic] synonym: "superior member long bone" EXACT [OBOL:automatic] synonym: "upper extremity long bone" EXACT [OBOL:automatic] xref: MA:0000299 ! forelimb long bone intersection_of: UBERON:0002495 ! long bone intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003608 name: hindlimb long bone def: "A long bone that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb long bone" EXACT [OBOL:automatic] synonym: "inferior member long bone" EXACT [OBOL:automatic] synonym: "long bone of hind limb" EXACT [OBOL:automatic] synonym: "long bone of hindlimb" EXACT [OBOL:automatic] synonym: "long bone of inferior member" EXACT [OBOL:automatic] synonym: "long bone of lower extremity" EXACT [OBOL:automatic] synonym: "lower extremity long bone" EXACT [OBOL:automatic] xref: MA:0000300 ! hindlimb long bone intersection_of: UBERON:0002495 ! long bone intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003609 name: aorta elastic tissue def: "the dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall." [MP:0009862] synonym: "adult aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "adult aorta elastic tissue" EXACT [OBOL:automatic] synonym: "adult aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "dorsal aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "dorsal aorta elastic tissue" EXACT [OBOL:automatic] synonym: "dorsal aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of adult aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of dorsal aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "elastic tissue of adult aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of dorsal aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of adult aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of dorsal aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "trunk of aortic tree elastic connective tissue" EXACT [OBOL:automatic] synonym: "trunk of aortic tree elastic tissue" EXACT [OBOL:automatic] synonym: "trunk of aortic tree textus connectivus elasticus" EXACT [OBOL:automatic] xref: MA:0002859 ! aorta elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0000947 ! aorta [Term] id: UBERON:0003610 name: heart elastic tissue def: "the type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers." [MP:0009863] synonym: "elastic connective tissue of heart" EXACT [OBOL:automatic] synonym: "elastic tissue of heart" EXACT [OBOL:automatic] synonym: "heart elastic connective tissue" EXACT [OBOL:automatic] synonym: "heart textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of heart" EXACT [OBOL:automatic] xref: MA:0002858 ! heart elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0003611 name: respiratory system elastic tissue def: "An elastic tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius elastic connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius elastic tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "elastic connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "elastic tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "elastic tissue of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system elastic connective tissue" EXACT [OBOL:automatic] synonym: "respiratory system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of respiratory system" EXACT [OBOL:automatic] xref: MA:0001820 ! respiratory system elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0004777 ! respiratory system submucosa [Term] id: UBERON:0003613 name: cardiovascular system elastic tissue def: "An elastic tissue that is part of a circulatory system [Automatically generated definition]." [OBOL:automatic] synonym: "cardiovascular system elastic connective tissue" EXACT [OBOL:automatic] synonym: "cardiovascular system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "circulatory system elastic connective tissue" EXACT [OBOL:automatic] synonym: "circulatory system elastic tissue" EXACT [OBOL:automatic] synonym: "circulatory system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of cardiovascular system" EXACT [OBOL:automatic] synonym: "elastic connective tissue of circulatory system" EXACT [OBOL:automatic] synonym: "elastic tissue of cardiovascular system" EXACT [OBOL:automatic] synonym: "elastic tissue of circulatory system" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of cardiovascular system" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of circulatory system" EXACT [OBOL:automatic] xref: MA:0002857 ! cardiovascular system elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0001009 ! circulatory system relationship: part_of UBERON:0004535 ! cardiovascular system [Term] id: UBERON:0003614 name: blood vessel elastic tissue def: "An elastic tissue that is part of a blood vessel [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel elastic connective tissue" EXACT [OBOL:automatic] synonym: "blood vessel textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of blood vessel" EXACT [OBOL:automatic] synonym: "elastic tissue of blood vessel" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of blood vessel" EXACT [OBOL:automatic] xref: MA:0002856 ! blood vessel elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0001981 ! blood vessel [Term] id: UBERON:0003615 name: lung elastic tissue def: "An elastic tissue that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "elastic connective tissue of lung" EXACT [OBOL:automatic] synonym: "elastic tissue of lung" EXACT [OBOL:automatic] synonym: "lung elastic connective tissue" EXACT [OBOL:automatic] synonym: "lung textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of lung" EXACT [OBOL:automatic] xref: MA:0002860 ! lung elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0002048 ! lung [Term] id: UBERON:0003616 name: bronchus elastic tissue def: "An elastic tissue that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi elastic connective tissue" EXACT [OBOL:automatic] synonym: "bronchi elastic tissue" EXACT [OBOL:automatic] synonym: "bronchi textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "bronchial trunk elastic connective tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk elastic tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "bronchus elastic connective tissue" EXACT [OBOL:automatic] synonym: "bronchus textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of bronchi" EXACT [OBOL:automatic] synonym: "elastic connective tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "elastic connective tissue of bronchus" EXACT [OBOL:automatic] synonym: "elastic tissue of bronchi" EXACT [OBOL:automatic] synonym: "elastic tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "elastic tissue of bronchus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of bronchi" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of bronchial trunk" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of bronchus" EXACT [OBOL:automatic] xref: MA:0001838 ! bronchus elastic tissue xref: ncithesaurus:Bronchus_Elastic_Tissue ! Bronchus Elastic Tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0001957 ! submucosa of bronchus xref: UMLS:C1707053 [Term] id: UBERON:0003617 name: trachea elastic tissue def: "An elastic tissue that is part of a trachea [Automatically generated definition]." [OBOL:automatic] synonym: "cartilaginous trachea elastic connective tissue" EXACT [OBOL:automatic] synonym: "cartilaginous trachea elastic tissue" EXACT [OBOL:automatic] synonym: "cartilaginous trachea textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "elastic connective tissue of vertebrate trachea" EXACT [OBOL:automatic] synonym: "elastic connective tissue of windpipe" EXACT [OBOL:automatic] synonym: "elastic tissue of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "elastic tissue of vertebrate trachea" EXACT [OBOL:automatic] synonym: "elastic tissue of windpipe" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of vertebrate trachea" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of windpipe" EXACT [OBOL:automatic] synonym: "vertebrate trachea elastic connective tissue" EXACT [OBOL:automatic] synonym: "vertebrate trachea elastic tissue" EXACT [OBOL:automatic] synonym: "vertebrate trachea textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "windpipe elastic connective tissue" EXACT [OBOL:automatic] synonym: "windpipe elastic tissue" EXACT [OBOL:automatic] synonym: "windpipe textus connectivus elasticus" EXACT [OBOL:automatic] xref: MA:0001861 ! trachea elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0002202 ! submucosa of trachea [Term] id: UBERON:0003618 ! aorta tunica media name: aorta tunica media def: "the middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers." [MP:0009873] synonym: "adult aorta tunica media" EXACT [OBOL:automatic] synonym: "dorsal aorta tunica media" EXACT [OBOL:automatic] synonym: "trunk of aortic tree tunica media" EXACT [OBOL:automatic] synonym: "tunica media of adult aorta" EXACT [OBOL:automatic] synonym: "tunica media of aorta" EXACT [OBOL:automatic] synonym: "tunica media of dorsal aorta" EXACT [OBOL:automatic] synonym: "tunica media of trunk of aortic tree" EXACT [OBOL:automatic] xref: MA:0002903 ! aorta tunica media xref: FMA:74433 ! Tunica media of aorta intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0000947 ! aorta relationship: part_of UBERON:0004663 ! aorta wall xref: SCTID:48467007 ! Aortic tunica media [Term] id: UBERON:0006563 ! tunica media of pulmonary trunk name: tunica media of pulmonary trunk def: "Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA]" [FMA:85030, FMA:FMA] xref: FMA:85030 ! tunica media of pulmonary trunk intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0002333 ! pulmonary trunk [Term] id: UBERON:0003619 name: aorta tunica intima def: "the innermost layer of the aorta, containing the endothelium and an inner elastic membrane." [MP:0009872] synonym: "adult aorta tunica intima" EXACT [OBOL:automatic] synonym: "dorsal aorta tunica intima" EXACT [OBOL:automatic] synonym: "trunk of aortic tree tunica intima" EXACT [OBOL:automatic] synonym: "tunica intima of adult aorta" EXACT [OBOL:automatic] synonym: "tunica intima of aorta" EXACT [OBOL:automatic] synonym: "tunica intima of dorsal aorta" EXACT [OBOL:automatic] synonym: "tunica intima of trunk of aortic tree" EXACT [OBOL:automatic] xref: MA:0002904 ! aorta tunica intima xref: FMA:74419 ! Tunica intima of aorta intersection_of: UBERON:0002523 ! tunica intima intersection_of: part_of UBERON:0000947 ! aorta relationship: part_of UBERON:0004663 ! aorta wall xref: SCTID:362031007 ! Entire aortic tunica intima [Term] id: UBERON:0005881 ! limb outgrowth name: limb outgrowth comment: encompasses digits and prepollex. requires review is_a: UBERON:0002529 ! limb segment [Term] id: UBERON:0002544 name: digit def: "one of several most distal parts of a limb, such as fingers or toes, present in many vertebrates[WP]." [Wikipedia:Digit_(anatomy)] comment: todo homology ZFA:0001588-pectoral fin distal radial. Note: This term is a GAT in FMA. Note: we elect to place a strict taxon constraint on this class - this is controversial, and may be weakened later on - see [Wikipedia:Digit_(anatomy)#Evolution]. AO notes: EMAPA mapping from TH subset: uberon_slim synonym: "limb digit" EXACT [MA:0000690] xref: EMAPA:32725 ! limb digit xref: EFO:0000881 ! digit xref: galen:Digit xref: VHOG:0000944 ! digits xref: MA:0000690 ! limb digit xref: MAT:0000285 ! digit xref: MIAA:0000285 ! digit xref: FMA:85518 ! Digit xref: ncithesaurus:Digit ! Digit xref: OpenCyc:Mx4rvzLD_ZwpEbGdrcN5Y29ycA ! digit xref: XAO:0003032 ! digit is_a: UBERON:0005881 ! limb outgrowth relationship: part_of UBERON:0012354 ! acropodium region relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of UBERON:0012140 {source="PHENOSCAPE:ni"} ! digitopodium region xref: SCTID:361367007 ! Entire digit xref: AAO:0011126 ! digit property_value: homology_notes "Our reinterpretation of the distal fin endoskeleton of Panderichthys removes the final piece of evidence supporting the formerly popular hypothesis that tetrapod digits are wholly new structures without homologues in sarcopterygian fish fins. This hypothesis, which was based partly on the complete absence of plausible digit homologues in Panderichthys (then the closest known relative of tetrapods), has already been called into question by the discovery of digit-like radials in Tiktaalik and the fact that Hox gene expression patterns closely resembling those associated with digit formation in tetrapods occur in the distal fin skeletons of paddlefish and Australian lungfish. Our new data show that Panderichthys is not an anomaly: like Tiktaalik and other fish members of the Tetrapodomorpha, it has distal radials that can be interpreted as digit homologues.[well established][VHOG]" xsd:string {external_class="VHOG:0000944", ontology="VHOG", source="DOI:10.1038/nature07339 Boisvert CA\, Mark-Kurik E and Ahlberg PE\, The pectoral fin of Panderichthys and the origin of digits. Nature (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "digital" xsd:string xref: UMLS:C0582802 [Term] id: UBERON:0005880 name: prepollex def: "A rudimentary additional digit-like structure on the preaxial side of the thumb of certain amphibians and mammals[dictionary.com]." [http://dictionary.com] comment: not homologous to digit 1 of tetrapods. Note we treat the prepollex as distinct from the digits, which are not part of the carpus synonym: "pseudothumb" RELATED [doi:10.1098/rsbl.2009.1038] is_a: UBERON:0005881 ! limb outgrowth relationship: part_of UBERON:0004452 ! carpal region relationship: preaxial_part_of UBERON:0004452 ! carpal region disjoint_from: UBERON:0002544 ! digit property_value: external_definition "Two or more elements located ventral and medial to the metacarpal of digit II(I). The proximal prepollex is small and round whereas distal prepollex 1 is usually large and wedge-shaped. When more elements are present, they are smaller than previous elements.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000852", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0012135 name: prepollex skeleton comment: A prepollex does not contain phalanges nor does it articulate with a metacarpal. It articulates with elements of the carpal (wrist) skeleton[AAO:DB]. TODO: add articulation relations synonym: "cartilago pre-pollicis" RELATED [AAO:0000852] synonym: "prepollex" BROAD [AAO:0000852] is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0005880 ! prepollex relationship: part_of UBERON:0009880 {source="AAO"} ! carpal skeleton relationship: preaxial_part_of UBERON:0009880 ! carpal skeleton xref: AAO:0000852 ! prepollex [Term] id: UBERON:0012136 ! prehallux name: prehallux is_a: UBERON:0005881 ! limb outgrowth disjoint_from: UBERON:0002544 ! digit relationship: part_of UBERON:0004454 ! tarsal region property_value: has_relational_adjective "prehallical" xsd:string [Term] id: UBERON:0006048 name: digit 1 is_a: UBERON:0002544 ! digit relationship: preaxial_part_of UBERON:0002470 ! autopod region property_value: ray_number "1" xsd:nonNegativeInteger synonym: "limb digit 1" EXACT [MA:00003023] synonym: "autopod digit 1" EXACT [] synonym: "dewclaw" NARROW SENSU [Wikipedia:Dewclaw] xref: MA:00003023 ! limb digit 1 [Term] id: UBERON:0006049 name: digit 2 is_a: UBERON:0002544 ! digit property_value: ray_number "2" xsd:nonNegativeInteger [Term] id: UBERON:0006050 name: digit 3 is_a: UBERON:0002544 ! digit property_value: ray_number "3" xsd:nonNegativeInteger [Term] id: UBERON:0006051 name: digit 4 is_a: UBERON:0002544 ! digit property_value: ray_number "4" xsd:nonNegativeInteger [Term] id: UBERON:0006052 name: digit 5 is_a: UBERON:0002544 ! digit property_value: ray_number "5" xsd:nonNegativeInteger [Term] id: UBERON:0001463 name: manual digit 1 def: "1st (preaxial) digit of the manus[Wikipedia]." [Wikipedia:Thumb, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553264] synonym: "hand digit 1" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1" EXACT [OBOL:accepted] comment: Not present in Anurans (Phenotype RCN Oct 2012) subset: uberon_slim synonym: "manual digit 1" EXACT [] synonym: "digit 1 of manus" EXACT [] synonym: "first digit of hand" EXACT [] synonym: "digitus primus [I]" BROAD [] synonym: "digitus 1" BROAD [] synonym: "pollex" EXACT [] synonym: "thumb" NARROW SENSU [] synonym: "alula" NARROW SENSU [Wikipedia:Alula] synonym: "digit 1 of fore-paw" EXACT [EMAPA:17429] synonym: "fore digit I" EXACT [AAO:0010639] synonym: "finger 1" EXACT [EHDAA2:0000511] synonym: "pollex" EXACT LATIN [Wikipedia:Thumb] synonym: "digitus primus" BROAD LATIN [Wikipedia:Thumb] synonym: "digitus I" BROAD LATIN [Wikipedia:Thumb] synonym: "hand digit 1" EXACT [MA:0000454] xref: FMA:24938 ! Thumb xref: GAID:58 ! thumb xref: MA:0000454 ! hand digit 1 xref: OpenCyc:Mx4rvVjVbpwpEbGdrcN5Y29ycA xref: ncithesaurus:Hand_Digit_1 ! Hand Digit 1 xref: OpenCyc:Mx4rvVjVbpwpEbGdrcN5Y29ycA ! thumb xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/64/Thumb-up.jpg/200px-Thumb-up.jpg xref: MESH:A01.378.800.667.430.705 ! thumb xref: EMAPA:17429 ! digit 1 of fore-paw xref: AAO:0010639 ! fore digit I is_a: UBERON:0002389 ! manual digit intersection_of: UBERON:0006048 intersection_of: part_of UBERON:0002398 ! manus relationship: preaxial_part_of UBERON:0002398 ! manus xref: SCTID:302540006 ! Entire thumb xref: EHDAA2:0000511 ! finger 1 xref: http://upload.wikimedia.org/wikipedia/commons/2/2c/Thumbs_up.jpg property_value: taxon_notes "This class represents the standard tetrapod configuration. Wagner proposes that avian digits I,II,III develop from C2,C3,C4. To support this scheme we have separate classes representing the avian digits (here called alula, manual digit, major digit)." xsd:string {scope="NCBITaxon:8782", source="PhenoscapeRCN", source="PMID:10220427", seeAlso="UBERON:0012260"} relationship: part_of UBERON:0012141 {source="reference_0000032"} ! manual digitopodium region xref: UMLS:C0040067 [Term] id: UBERON:0012260 name: alula (Aves) def: "A manual digit found in Aves that is the most preaxial position and is morphologically similar to digit 1 in the standard tetrapod configuration and develops from embryonic digit 2, with contributions from embryonic digit 1." [PhenoscapeRCN:Oct2012, PMID:10220427] comment: Hypothesized to be homologous to manual digit 1 of other tetrapods. Develops from the embryonic digit that is positionally the 2nd, with contributions from the 1st synonym: "wing digit I" RELATED [] synonym: "wing digit 1 (adult)" RELATED [] synonym: "wing digit 2 (embryonic)" RELATED [] synonym: "alula" RELATED [] synonym: "digit I of manus" RELATED [] synonym: "digit I(CII) of manus" RELATED [] is_a: UBERON:0002389 ! manual digit relationship: preaxial_part_of UBERON:0002398 ! manus relationship: present_in_taxon NCBITaxon:8782 ! Aves relationship: has_developmental_contribution_from UBERON:0005692 {source="PMID:10220427"} ! manual digit 2 mesenchyme relationship: has_developmental_contribution_from UBERON:0010564 {source="PMID:10220427"} ! manual digit 1 mesenchyme [Term] id: UBERON:0003622 name: manual digit 2 def: "2nd digit of the manus." [Wikipedia:Index_finger] synonym: "hand digit 2" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2" EXACT [OBOL:accepted] comment: Anurans lack manual digit 1, so manual digit 2 is the digit after the prepollex (Phenotype RCN Oct 2012) synonym: "2nd digit of hand" EXACT [] synonym: "2nd finger" EXACT [] synonym: "index finger" NARROW [] synonym: "second finger" EXACT [] synonym: "second digit of hand" EXACT [FMA:24946] synonym: "digit 2 of fore-paw" EXACT [EMAPA:17432] synonym: "fore digit II" EXACT [AAO:0010640] xref: FMA:24946 ! Index finger xref: MA:0000455 ! hand digit 2 synonym: "hand digit 2" EXACT [MA:0000455] xref: ncithesaurus:Hand_Digit_2 ! Hand Digit 2 xref: EHDAA2:0000517 ! finger 2 synonym: "finger 2" EXACT [EHDAA2:0000517] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/d5/Index_finger.JPG/200px-Index_finger.JPG xref: EMAPA:17432 ! digit 2 of fore-paw xref: AAO:0010640 ! fore digit II is_a: UBERON:0002389 ! manual digit intersection_of: UBERON:0006049 intersection_of: part_of UBERON:0002398 ! manus xref: http://upload.wikimedia.org/wikipedia/commons/d/d5/Index_finger.JPG xref: SCTID:362758006 ! Entire index finger property_value: taxon_notes "This class represents the standard tetrapod configuration. Wagner proposes that avian digits I,II,III develop from C2,C3,C4. To support this scheme we have separate classes representing the avian digits (here called alula, manual digit, major digit)." xsd:string {scope="NCBITaxon:8782", source="PhenoscapeRCN", source="PMID:10220427", seeAlso="UBERON:0012261"} relationship: part_of UBERON:0012141 {source="reference_0000032"} ! manual digitopodium region xref: UMLS:C0230388 [Term] id: UBERON:0012261 name: manual major digit (Aves) def: "A manual digit found in Aves that is morphologically similar to digit 2 in the standard tetrapod configuration and develops from embryonic digit 3." [PhenoscapeRCN:Oct2012, PMID:10220427] comment: Hypothesized to be homologous to manual digit 2 of other tetrapods synonym: "wing digit II" RELATED [] synonym: "wing digit 2 (adult)" RELATED [] synonym: "wing digit 3 (embryonic)" RELATED [] synonym: "manual major digit" RELATED [] synonym: "digit II of manus" RELATED [] synonym: "digit II(CIII) of manus" RELATED [] is_a: UBERON:0002389 ! manual digit relationship: present_in_taxon NCBITaxon:8782 ! Aves relationship: has_developmental_contribution_from UBERON:0005693 {source="PMID:10220427"} ! manual digit 3 mesenchyme [Term] id: UBERON:0003623 name: manual digit 3 def: "3rd digit of the manus." [Wikipedia:Middle_finger] synonym: "hand digit 3" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3" EXACT [OBOL:accepted] synonym: "3rd digit of hand" EXACT [] synonym: "3rd finger" EXACT [] synonym: "middle finger" NARROW [] synonym: "third finger" EXACT [] synonym: "third digit of hand" EXACT [FMA:24947] synonym: "digit 3 of fore-paw" EXACT [EMAPA:17435] synonym: "fore digit III" EXACT [AAO:0010641] xref: FMA:24947 ! Middle finger xref: MA:0000456 ! hand digit 3 xref: ncithesaurus:Hand_Digit_3 ! Hand Digit 3 xref: EHDAA2:0000523 ! finger 3 synonym: "finger 3" EXACT [EHDAA2:0000523] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fd/Middle_finger.jpg/200px-Middle_finger.jpg xref: EMAPA:17435 ! digit 3 of fore-paw xref: AAO:0010641 ! fore digit III is_a: UBERON:0002389 ! manual digit intersection_of: UBERON:0006050 intersection_of: part_of UBERON:0002398 ! manus synonym: "digitus medius" RELATED LATIN [Wikipedia:Middle_finger] xref: http://upload.wikimedia.org/wikipedia/commons/f/fd/Middle_finger.jpg xref: SCTID:362763005 ! Entire middle finger synonym: "hand digit 3" EXACT [MA:0000456] property_value: taxon_notes "This class represents the standard tetrapod configuration. Wagner proposes that avian digits I,II,III develop from C2,C3,C4. To support this scheme we have separate classes representing the avian digits (here called alula, manual digit, major digit)." xsd:string {scope="NCBITaxon:8782", source="PhenoscapeRCN", source="PMID:10220427", seeAlso="UBERON:0012262"} relationship: part_of UBERON:0012141 {source="reference_0000032"} ! manual digitopodium region xref: UMLS:C0230393 [Term] id: UBERON:0012262 name: manual minor digit (Aves) def: "A manual digit found in Aves that is morphologically similar to digit 3 in the standard tetrapod configuration and develops from embryonic digit 4." [PhenoscapeRCN:Oct2012, PMID:10220427] comment: Hypothesized to be homologous to manual digit 3 of other tetrapods synonym: "wing digit III" RELATED [] synonym: "wing digit 3 (adult)" RELATED [] synonym: "wing digit 4 (embryonic)" RELATED [] synonym: "manual minor digit" RELATED [] synonym: "digit III of manus" RELATED [] synonym: "digit III(CIV) of manus" RELATED [] is_a: UBERON:0002389 ! manual digit relationship: postaxial_part_of UBERON:0002398 ! manus relationship: present_in_taxon NCBITaxon:8782 ! Aves relationship: has_developmental_contribution_from UBERON:0005694 {source="PMID:10220427"} ! manual digit 4 mesenchyme [Term] id: UBERON:0003624 name: manual digit 4 def: "4th digit of the manus." [Wikipedia:Ring_finger] synonym: "hand digit 4" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4" EXACT [OBOL:accepted] synonym: "4th digit of hand" EXACT [] synonym: "4th finger" EXACT [] synonym: "fourth finger" EXACT [] synonym: "ring finger" NARROW [] synonym: "fourth digit of hand" EXACT [FMA:24948] synonym: "digit 4 of fore-paw" EXACT [EMAPA:17438] synonym: "fore digit IV" EXACT [AAO:0010642] synonym: "finger 4" EXACT [EHDAA2:0000529] xref: FMA:24948 ! Ring finger xref: MA:0000457 ! hand digit 4 xref: ncithesaurus:Hand_Digit_4 ! Hand Digit 4 xref: EHDAA2:0000529 ! finger 4 xref: AAO:0010642 ! fore digit IV xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/14/Ring_finger.JPG/200px-Ring_finger.JPG xref: EMAPA:17438 ! digit 4 of fore-paw is_a: UBERON:0002389 ! manual digit intersection_of: UBERON:0006051 intersection_of: part_of UBERON:0002398 ! manus synonym: "digitus annularis" RELATED LATIN [Wikipedia:Ring_finger] xref: http://upload.wikimedia.org/wikipedia/commons/1/14/Ring_finger.JPG xref: SCTID:362768001 ! Entire ring finger synonym: "hand digit 4" EXACT [MA:0000457] relationship: part_of UBERON:0012141 {source="reference_0000032"} ! manual digitopodium region xref: UMLS:C0230398 [Term] id: UBERON:0003625 name: manual digit 5 def: "5th digit of the manus." [Wikipedia:Little_finger] synonym: "hand digit 5" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5" EXACT [OBOL:accepted] synonym: "5th digit of hand" EXACT [] synonym: "5th finger" EXACT [] synonym: "fifth finger" EXACT [] synonym: "little finger" NARROW [] synonym: "fifth digit of hand" EXACT [FMA:24949] synonym: "digit 5 of fore-paw" EXACT [EMAPA:17441] synonym: "fore digit V" EXACT [AAO:0010643] xref: FMA:24949 ! Little finger xref: MA:0000458 ! hand digit 5 xref: ncithesaurus:Hand_Digit_5 ! Hand Digit 5 xref: EHDAA2:0000535 ! finger 5 xref: AAO:0010643 ! fore digit V synonym: "finger 5" EXACT [EHDAA2:0000535] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Pink.jpg/200px-Pink.jpg xref: EMAPA:17441 ! digit 5 of fore-paw is_a: UBERON:0002389 ! manual digit intersection_of: UBERON:0006052 intersection_of: part_of UBERON:0002398 ! hand synonym: "quintus, digitus V" RELATED LATIN [Wikipedia:Little_finger] synonym: "manual digitus minimus" RELATED LATIN [Wikipedia:Little_finger] xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Pink.jpg xref: SCTID:362773007 ! Entire little finger synonym: "hand digit 5" EXACT [MA:0000458] relationship: part_of UBERON:0012141 {source="reference_0000032"} ! manual digitopodium region xref: UMLS:C0230403 [Term] id: UBERON:0011981 name: manual digit 6 synonym: "hand digit 6" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 6" EXACT [OBOL:accepted] comment: Found in Acanthostega synonym: "fore digit VI" EXACT [] synonym: "6th finger" EXACT [] synonym: "sixth finger" EXACT [] is_a: UBERON:0002389 ! manual digit property_value: ray_number "6" xsd:nonNegativeInteger [Term] id: UBERON:0011982 name: manual digit 7 synonym: "hand digit 7" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 7" EXACT [OBOL:accepted] comment: Found in Acanthostega synonym: "fore digit VII" EXACT [] synonym: "seventh finger" EXACT [] is_a: UBERON:0002389 ! manual digit property_value: ray_number "7" xsd:nonNegativeInteger [Term] id: UBERON:0011983 name: manual digit 8 synonym: "hand digit 8" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 8" EXACT [OBOL:accepted] comment: Found in Acanthostega synonym: "fore digit VIII" EXACT [] synonym: "eighth finger" EXACT [] is_a: UBERON:0002389 ! manual digit property_value: ray_number "8" xsd:nonNegativeInteger [Term] id: UBERON:0003631 name: pedal digit 1 def: "1st digit of the hind autopod." [Wikipedia:Hallux] synonym: "pes digit I" EXACT [] synonym: "foot digit 1" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1" EXACT [OBOL:accepted] synonym: "preaxial digit of hindlimb" EXACT [] synonym: "pedal digit 1" EXACT [] synonym: "digit 1 of pes" EXACT [] synonym: "great toe" EXACT [FMA:25047] synonym: "hallux" EXACT LATIN [FMA:TA] synonym: "hallux; digitus primus [I]" EXACT [FMA:25047] synonym: "hallex" EXACT [] synonym: "big toe" NARROW [] synonym: "digitus primus (I) pedis" RELATED [BTO:0002349] synonym: "digit 1 of hind-paw" EXACT [EMAPA:17460] synonym: "hind digit I" EXACT [AAO:0010644] synonym: "toe 1" EXACT [EHDAA2:0002037] xref: FMA:25047 ! Big toe xref: MA:0000465 ! foot digit 1 xref: EMAPA:17460 ! digit 1 of hind-paw xref: ncithesaurus:Foot_Digit_1 ! Foot Digit 1 xref: GAID:45 ! hallux xref: BTO:0002349 ! hallux xref: MESH:A01.378.610.250.300.792.380 ! hallux xref: EMAPA:17460 ! digit 1 of hind-paw is_a: UBERON:0001466 ! pedal digit intersection_of: UBERON:0006048 intersection_of: part_of UBERON:0002387 ! pes relationship: preaxial_part_of UBERON:0002387 ! pes xref: EHDAA2:0002037 ! toe 1 xref: AAO:0010644 ! hind digit I xref: VSAO:0000201 ! hallux xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/RightFootToes.jpg xref: SCTID:302546000 ! Entire great toe synonym: "foot digit 1" EXACT [MA:0000465] relationship: part_of UBERON:0012142 {source="reference_0000032"} ! pedal digitopodium region xref: UMLS:C1708079 [Term] id: UBERON:0003632 name: pedal digit 2 def: "2nd digit of the hind autopod." [UBERON:cjm] synonym: "pes digit II" EXACT [] synonym: "foot digit 2" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2" EXACT [OBOL:accepted] synonym: "2nd toe" EXACT [] synonym: "second toe" EXACT [FMA:25048] synonym: "digitus secundus [ii]" EXACT [FMA:25048] synonym: "second digit of foot" EXACT [FMA:25048] synonym: "digit 2 of hind-paw" EXACT [EMAPA:17463] xref: FMA:25048 ! Second toe xref: MA:0000466 ! foot digit 2 xref: ncithesaurus:Foot_Digit_2 ! Foot Digit 2 xref: EHDAA2:0002042 ! toe 2 synonym: "toe 2" EXACT [EHDAA2:0002042] xref: EMAPA:17463 ! digit 2 of hind-paw xref: BTO:0002350 ! digitus secundus pedis synonym: "digitus secundus pedis" EXACT [BTO:0002350] synonym: "digitus secundus (II) pedis" RELATED [BTO:0002350] is_a: UBERON:0001466 ! pedal digit intersection_of: UBERON:0006049 intersection_of: part_of UBERON:0002387 ! pes xref: SCTID:362817008 ! Entire second toe xref: AAO:0010645 ! hind digit II synonym: "hind digit II" EXACT [AAO:0010645] synonym: "foot digit 2" EXACT [MA:0000466] relationship: part_of UBERON:0012142 {source="reference_0000032"} ! pedal digitopodium region xref: UMLS:C1708081 [Term] id: UBERON:0003633 name: pedal digit 3 def: "3rd digit of the hind autopod." [UBERON:cjm] synonym: "pes digit III" EXACT [] synonym: "foot digit 3" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3" EXACT [OBOL:accepted] synonym: "3rd toe" EXACT [] synonym: "third toe" EXACT [FMA:25051] synonym: "digitus tertius [iii]" EXACT [FMA:25051] synonym: "third digit of foot" EXACT [FMA:25051] synonym: "digit 3 of hind-paw" EXACT [EMAPA:17466] xref: FMA:25051 ! Third toe xref: MA:0000467 ! foot digit 3 xref: ncithesaurus:Foot_Digit_3 ! Foot Digit 3 xref: EHDAA2:0002047 ! toe 3 synonym: "toe 3" EXACT [EHDAA2:0002047] xref: EMAPA:17466 ! digit 3 of hind-paw xref: BTO:0002351 ! digitus tertius pedis synonym: "digitus tertius pedis" EXACT [BTO:0002351] synonym: "digitus tertius (III) pedis" RELATED [BTO:0002351] is_a: UBERON:0001466 ! pedal digit intersection_of: UBERON:0006050 intersection_of: part_of UBERON:0002387 ! pes xref: SCTID:362821001 ! Entire third toe xref: AAO:0010646 ! hind digit III synonym: "hind digit III" EXACT [AAO:0010646] synonym: "foot digit 3" EXACT [MA:0000467] relationship: part_of UBERON:0012142 {source="reference_0000032"} ! pedal digitopodium region xref: UMLS:C1708083 [Term] id: UBERON:0003634 name: pedal digit 4 def: "4th digit of the hind autopod." [UBERON:cjm] synonym: "pes digit IV" EXACT [] synonym: "foot digit 4" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4" EXACT [OBOL:accepted] synonym: "4th toe" EXACT [] synonym: "fourth toe" EXACT [FMA:25052] synonym: "digitus quartus [iv]" EXACT [FMA:25052] synonym: "fourth digit of foot" EXACT [FMA:25052] synonym: "digit 4 of hind-paw" EXACT [EMAPA:17469] xref: FMA:25052 ! Fourth toe xref: MA:0000468 ! foot digit 4 xref: ncithesaurus:Foot_Digit_4 ! Foot Digit 4 xref: EHDAA2:0002052 ! toe 4 synonym: "toe 4" EXACT [EHDAA2:0002052] xref: EMAPA:17469 ! digit 4 of hind-paw xref: BTO:0002352 ! digitus quartis pedis synonym: "digitus quartis pedis" EXACT [BTO:0002352] synonym: "digitus quartus (IV) pedis" RELATED [BTO:0002352] is_a: UBERON:0001466 ! pedal digit is_a: UBERON:0006051 relationship: part_of UBERON:0002387 ! pes xref: SCTID:362826006 ! Entire fourth toe xref: AAO:0010656 ! hind digit IV synonym: "hind digit IV" EXACT [AAO:0010656] synonym: "foot digit 4" EXACT [MA:0000468] xref: UMLS:C1708085 [Term] id: UBERON:0003635 name: pedal digit 5 def: "5th digit of the hind autopod." [UBERON:cjm, Wikipedia:Fifth_toe] synonym: "pes digit V" EXACT [] synonym: "foot digit 5" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5" EXACT [OBOL:accepted] synonym: "5th toe" EXACT [] synonym: "little toe" NARROW [] synonym: "pedal digitus minimus" EXACT [] synonym: "digitus quintus of pes" EXACT [] synonym: "digitus V of pes" EXACT [] synonym: "fifth digit of foot" EXACT [FMA:25053] synonym: "fifth toe" EXACT [FMA:25053] synonym: "digit 5 of hind-paw" EXACT [EMAPA:17472] xref: FMA:25053 ! Little toe xref: MA:0000469 ! foot digit 5 xref: ncithesaurus:Foot_Digit_5 ! Foot Digit 5 xref: EHDAA2:0002057 ! toe 5 synonym: "toe 5" EXACT [EHDAA2:0002057] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/52/Gray291.png/200px-Gray291.png xref: BTO:0002353 ! digitum minimus pedis xref: EMAPA:17472 ! digit 5 of hind-paw is_a: UBERON:0001466 ! pedal digit intersection_of: UBERON:0006052 intersection_of: part_of UBERON:0002387 ! pes synonym: "digitus quintus [V] pedis" EXACT LATIN [FMA:TA, FMA:25053] xref: SCTID:362830009 ! Entire fifth toe xref: AAO:0010658 ! hind digit V synonym: "hind digit V" EXACT [AAO:0010658] synonym: "digitus minimus pedis" RELATED LATIN [Wikipedia:Fifth_toe] synonym: "digitus quintus pedis" RELATED LATIN [Wikipedia:Fifth_toe] xref: http://upload.wikimedia.org/wikipedia/commons/5/52/Gray291.png synonym: "foot digit 5" EXACT [MA:0000469] relationship: part_of UBERON:0012142 {source="reference_0000032"} ! pedal digitopodium region xref: UMLS:C1708087 [Term] id: UBERON:0011984 name: pedal digit 6 synonym: "pes digit VI" EXACT [] synonym: "foot digit 6" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 6" EXACT [OBOL:accepted] synonym: "hind digit VI" EXACT [] synonym: "sixth toe" EXACT [] synonym: "toe 6" EXACT [] synonym: "hind digit 6" EXACT [] is_a: UBERON:0001466 ! pedal digit property_value: ray_number "6" xsd:nonNegativeInteger [Term] id: UBERON:0012137 name: pedal digit 7 synonym: "pes digit VII" EXACT [] synonym: "foot digit 7" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 7" EXACT [OBOL:accepted] synonym: "hind digit VII" EXACT [] synonym: "seventh toe" EXACT [] synonym: "toe 7" EXACT [] synonym: "hind digit 7" EXACT [] is_a: UBERON:0001466 ! pedal digit property_value: ray_number "7" xsd:nonNegativeInteger [Term] id: UBERON:0012138 name: pedal digit 8 synonym: "pes digit VIII" EXACT [] synonym: "foot digit 8" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 8" EXACT [OBOL:accepted] synonym: "hind digit VIII" EXACT [] synonym: "eigth toe" EXACT [] synonym: "toe 8" EXACT [] synonym: "hind digit 8" EXACT [] is_a: UBERON:0001466 ! pedal digit property_value: ray_number "8" xsd:nonNegativeInteger [Term] id: UBERON:0003864 name: middle phalanx of manus def: "A middle phalanx that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "middle phalanx of hand" EXACT [] synonym: "middle manual phalanx" EXACT [] synonym: "hand middle phalanx" EXACT [MA:0001394] synonym: "middle phalanx of hand" EXACT [MA:0001394] synonym: "middle phalanx of finger" EXACT [FMA:75817] synonym: "middle phalanx of manual digit" EXACT [] xref: MA:0001394 ! middle phalanx of hand xref: FMA:75817 ! middle phalanx of finger xref: ncithesaurus:Middle_Phalanx_of_the_Hand ! Middle Phalanx of Hand is_a: UBERON:0001436 ! phalanx of manus intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: proximally_connected_to UBERON:0001436 ! phalanx of manus relationship: distally_connected_to UBERON:0001436 ! phalanx of manus xref: SCTID:113223004 ! Structure of middle phalanx of middle finger xref: SCTID:371230003 ! Entire middle phalanx of hand xref: UMLS:C0223828 [Term] id: UBERON:0003865 name: distal phalanx of manus def: "A distal phalanx that is part of a finger [Automatically generated definition]." [OBOL:automatic] comment: This is typically proximally connected to the middle phalanx of manus, except in some cases such as the human thumb, where it connects to the proximal phalanx. It always connects to some phalanx, by definition synonym: "distal manual phalanx" EXACT [] synonym: "ungual phalanx of hand" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] synonym: "terminal phalanx of hand" EXACT [UBERON:cjm] synonym: "distal phalanx of manual digit" EXACT [] synonym: "distal phalanx of hand" EXACT [] synonym: "hand distal phalanx" EXACT [MA:0001388] synonym: "distal phalanx of finger" EXACT [FMA:75818] xref: MA:0001388 ! distal phalanx of hand xref: FMA:75818 ! distal phalanx of finger xref: ncithesaurus:Distal_Phalanx_of_Hand ! Distal Phalanx of Hand is_a: UBERON:0001436 ! phalanx of manus intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0009552 ! distal segment of manual digit relationship: proximally_connected_to UBERON:0001436 ! phalanx of manus xref: SCTID:182001007 ! Entire distal phalanx of finger xref: SCTID:361782004 ! Entire distal phalanx of hand xref: UMLS:C1269782 [Term] id: UBERON:0002234 name: proximal phalanx of manus def: "A proximal phalanx that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "proximal manual phalanx" EXACT [] synonym: "proximal phalanx of hand" EXACT [] synonym: "proximal phalanx of manual digit" EXACT [] synonym: "proximal phalanx of fore digit" EXACT [] synonym: "hand proximal phalanx" EXACT [MA:0001395] synonym: "proximal phalanx of finger" EXACT [FMA:75816] xref: FMA:75816 ! Proximal phalanx of finger xref: MA:0001395 ! proximal phalanx of hand xref: ncithesaurus:Proximal_Phalanx_of_Hand ! Proximal Phalanx of Hand is_a: UBERON:0001436 ! phalanx of manus intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: proximally_connected_to UBERON:0002374 ! metacarpal bone xref: SCTID:181986000 ! Entire proximal phalanx of finger xref: SCTID:361325003 ! Entire proximal phalanx of hand xref: UMLS:C0730117 [Term] id: UBERON:0003866 name: middle phalanx of pes def: "A middle phalanx that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "middle pedal phalanx" EXACT [] synonym: "middle phalanx of foot" EXACT [] synonym: "foot middle phalanx" EXACT [MA:0001386] synonym: "middle phalanx of toe" EXACT [FMA:75829] xref: FMA:75829 ! middle phalanx of toe xref: MA:0001386 ! middle phalanx of foot is_a: UBERON:0001449 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0001466 ! pedal digit relationship: proximally_connected_to UBERON:0001449 ! phalanx of pes relationship: distally_connected_to UBERON:0001449 ! phalanx of pes xref: SCTID:83207005 ! Entire middle phalanx of foot [Term] id: UBERON:0003867 name: distal phalanx of pes def: "A distal phalanx that is part of a pedal digit [Automatically generated definition]." [OBOL:automatic] comment: This is typically proximally connected to the middle phalanx of pes, except in some cases such as the human big toe, where it connects to the proximal phalanx. It always connects to some phalanx, by definition synonym: "distal pedal phalanx" EXACT [] synonym: "ungual phalanx of foot" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] synonym: "ungual phalanx of hindlimb" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] synonym: "terminal phalanx of foot" EXACT [UBERON:cjm] synonym: "terminal phalanx of hindlimb" EXACT [UBERON:cjm] synonym: "distal phalanx of foot" EXACT [] synonym: "foot distal phalanx" EXACT [MA:0001380] synonym: "distal phalanx of toe" EXACT [FMA:75830] xref: FMA:75830 ! distal phalanx of toe xref: MA:0001380 ! distal phalanx of foot xref: ncithesaurus:Distal_Phalanx_of_Foot ! Distal Phalanx of Foot is_a: UBERON:0001449 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0009553 ! distal segment of pedal digit relationship: proximally_connected_to UBERON:0001449 ! phalanx of pes xref: SCTID:361797001 ! Entire distal phalanx of foot xref: UMLS:C0224026 [Term] id: UBERON:0003868 name: proximal phalanx of pes def: "A proximal phalanx that is part of a pedal digit [Automatically generated definition]." [OBOL:automatic] synonym: "proximal pedal phalanx" EXACT [] synonym: "proximal phalanx of foot" EXACT [] synonym: "proximal phalanx of pes" EXACT [] synonym: "proximal phalanx of foot digit" EXACT [] synonym: "proximal phalanx of hind digit" EXACT [] synonym: "foot proximal phalanx" EXACT [MA:0001387] synonym: "proximal phalanx of toe" EXACT [FMA:75828] xref: FMA:75828 ! proximal phalanx of toe xref: MA:0001387 ! proximal phalanx of foot xref: ncithesaurus:Proximal_Phalanx_of_Foot ! Proximal Phalanx of Foot is_a: UBERON:0001449 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0001466 ! pedal digit relationship: proximally_connected_to UBERON:0001448 ! metatarsal bone xref: SCTID:85533000 ! Entire proximal phalanx of foot xref: UMLS:C0224020 [Term] id: UBERON:0001436 name: phalanx of manus def: "A phalanx that is part of a forelimb autopod[Automatically generated definition]." [UBERON:cjm, Wikipedia:Phalanges_of_the_hand] synonym: "manual phalanx" EXACT [] synonym: "hand phalanx" EXACT [] synonym: "phalanx of hand" EXACT [] synonym: "phalanx of manual digit" EXACT [] synonym: "phalanges of fore digit" RELATED PLURAL [AAO:0000947] synonym: "phalanges of fore digit" RELATED PLURAL [AAO:0000947] synonym: "phalanx of fore digit" EXACT [] synonym: "hand phalanx" EXACT [MA:0000306] synonym: "digitus manus phalanx" EXACT [OBOL:automatic] synonym: "finger phalanx" EXACT [OBOL:automatic] synonym: "digital bone of manus" EXACT [OBOL:automatic] synonym: "hand digit phalanx" EXACT [OBOL:automatic] synonym: "phalanx of digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of digitus manus" EXACT [OBOL:automatic] synonym: "phalanx of hand digit" EXACT [OBOL:automatic] synonym: "phalanx of finger" EXACT [FMA:23914] xref: http://mbe.oxfordjournals.org/content/26/3/613/F1.large.jpg xref: FMA:23914 ! phalanx of finger xref: MA:0000306 ! hand phalanx xref: AAO:0000947 ! phalanges of fore digit xref: ncithesaurus:Hand_Phalanx ! Hand Phalanx intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0010688 ! skeleton of anterior acropodium xref: SCTID:181976001 ! Entire phalanx of finger xref: SCTID:361100001 ! Entire phalanx of hand relationship: develops_from UBERON:0010686 ! finger phalanx cartilage condensation property_value: external_definition "Dumb-bell shaped bones of endochondral origin with cartilaginous epiphyses that make the four digits of the manus. The terminal phalanges are much smaller than the proximal and penultimate phalanges. The typical phalangeal formula of the manus, in a medial to lateral sequence, is 2-2-3-3.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000947", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0223792 [Term] id: UBERON:0003620 name: manual digit 1 phalanx def: "A phalanx that is part of a hand digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit 1 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1 phalanx" EXACT [OBOL:accepted] synonym: "Pollex ; Digitus primus [ I ] phalanx" EXACT [OBOL:automatic] synonym: "first digit of hand phalanx" EXACT [OBOL:automatic] synonym: "phalanx of Pollex ; Digitus primus [ I ]" EXACT [OBOL:automatic] synonym: "phalanx of first digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 1" EXACT [OBOL:automatic] synonym: "phalanx of thumb" EXACT [OBOL:automatic] synonym: "thumb phalanx" EXACT [OBOL:automatic] synonym: "Pollex ; Digitus primus [ I ] digit long bone" EXACT [OBOL:automatic] synonym: "Pollex ; Digitus primus [ I ] long bone of digit" EXACT [OBOL:automatic] synonym: "digit long bone of Pollex ; Digitus primus [ I ]" EXACT [OBOL:automatic] synonym: "digit long bone of first digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 1" EXACT [OBOL:automatic] synonym: "digit long bone of thumb" EXACT [OBOL:automatic] synonym: "first digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "first digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "hand digit 1 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 1 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of Pollex ; Digitus primus [ I ]" EXACT [OBOL:automatic] synonym: "long bone of digit of first digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 1" EXACT [OBOL:automatic] synonym: "long bone of digit of thumb" EXACT [OBOL:automatic] synonym: "thumb digit long bone" EXACT [OBOL:automatic] synonym: "thumb long bone of digit" EXACT [OBOL:automatic] xref: MA:0001389 ! hand digit 1 phalanx xref: ncithesaurus:Hand_Digit_1_Phalanx ! Hand Digit 1 Phalanx xref: FMA:35477 ! Phalanx of thumb intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0001463 ! manual digit 1 xref: SCTID:181975002 ! Entire phalanx of thumb xref: EMAPA:19113 ! phalanx of digit 1 of fore-paw relationship: develops_from UBERON:0010675 ! finger 1 phalanx cartilage condensation synonym: "hand digit 1 phalanx" EXACT [MA:0001389] xref: UMLS:C1711344 [Term] id: UBERON:0003636 name: manual digit 2 phalanx def: "A phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit 2 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2 phalanx" EXACT [OBOL:accepted] synonym: "2 nd digit of hand phalanx" EXACT [OBOL:automatic] synonym: "2 nd finger phalanx" EXACT [OBOL:automatic] synonym: "phalanx of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 2 nd finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 2" EXACT [OBOL:automatic] synonym: "phalanx of second finger" EXACT [OBOL:automatic] synonym: "second finger phalanx" EXACT [OBOL:automatic] synonym: "2 nd digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "2 nd digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "2 nd finger digit long bone" EXACT [OBOL:automatic] synonym: "2 nd finger long bone of digit" EXACT [OBOL:automatic] synonym: "digit long bone of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 2 nd finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 2" EXACT [OBOL:automatic] synonym: "digit long bone of second finger" EXACT [OBOL:automatic] synonym: "hand digit 2 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 2 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 2 nd finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 2" EXACT [OBOL:automatic] synonym: "long bone of digit of second finger" EXACT [OBOL:automatic] synonym: "second finger digit long bone" EXACT [OBOL:automatic] synonym: "second finger long bone of digit" EXACT [OBOL:automatic] synonym: "phalanx of index finger" EXACT [FMA:35480] synonym: "index finger phalanx" EXACT [FMA:35480] xref: MA:0001390 ! hand digit 2 phalanx xref: ncithesaurus:Hand_Digit_2_Phalanx ! Hand Digit 2 Phalanx xref: FMA:35480 ! Phalanx of index finger intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003622 ! manual digit 2 xref: SCTID:361783009 ! Entire phalanx of index finger xref: EMAPA:19115 ! phalanx of digit 2 of fore-paw relationship: develops_from UBERON:0010676 ! finger 2 phalanx cartilage condensation synonym: "hand digit 2 phalanx" EXACT [MA:0001390] xref: UMLS:C1708312 [Term] id: UBERON:0003637 name: manual digit 3 phalanx def: "A phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit 3 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3 phalanx" EXACT [OBOL:accepted] synonym: "3 rd digit of hand phalanx" EXACT [OBOL:automatic] synonym: "3 rd finger phalanx" EXACT [OBOL:automatic] synonym: "phalanx of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 3 rd finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 3" EXACT [OBOL:automatic] synonym: "phalanx of third finger" EXACT [OBOL:automatic] synonym: "third finger phalanx" EXACT [OBOL:automatic] synonym: "3 rd digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "3 rd digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "3 rd finger digit long bone" EXACT [OBOL:automatic] synonym: "3 rd finger long bone of digit" EXACT [OBOL:automatic] synonym: "digit long bone of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 3 rd finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 3" EXACT [OBOL:automatic] synonym: "digit long bone of third finger" EXACT [OBOL:automatic] synonym: "hand digit 3 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 3 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 3 rd finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 3" EXACT [OBOL:automatic] synonym: "long bone of digit of third finger" EXACT [OBOL:automatic] synonym: "third finger digit long bone" EXACT [OBOL:automatic] synonym: "third finger long bone of digit" EXACT [OBOL:automatic] synonym: "phalanx of middle finger" EXACT [FMA:35483] synonym: "middle finger phalanx" EXACT [FMA:35483] xref: MA:0001391 ! hand digit 3 phalanx xref: ncithesaurus:Hand_Digit_3_Phalanx ! Hand Digit 3 Phalanx xref: FMA:35483 ! Phalanx of middle finger intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003623 ! manual digit 3 xref: SCTID:361785002 ! Entire phalanx of middle finger xref: EMAPA:19117 ! phalanx of digit 3 of fore-paw relationship: develops_from UBERON:0010677 ! finger 3 phalanx cartilage condensation synonym: "hand digit 3 phalanx" EXACT [MA:0001391] xref: UMLS:C1708314 [Term] id: UBERON:0003638 name: manual digit 4 phalanx def: "A phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit 4 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4 phalanx" EXACT [OBOL:accepted] synonym: "4 th digit of hand phalanx" EXACT [OBOL:automatic] synonym: "4 th finger phalanx" EXACT [OBOL:automatic] synonym: "fourth finger phalanx" EXACT [OBOL:automatic] synonym: "phalanx of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 4 th finger" EXACT [OBOL:automatic] synonym: "phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 4" EXACT [OBOL:automatic] synonym: "4 th digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "4 th digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "4 th finger digit long bone" EXACT [OBOL:automatic] synonym: "4 th finger long bone of digit" EXACT [OBOL:automatic] synonym: "digit long bone of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 4 th finger" EXACT [OBOL:automatic] synonym: "digit long bone of fourth finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 4" EXACT [OBOL:automatic] synonym: "fourth finger digit long bone" EXACT [OBOL:automatic] synonym: "fourth finger long bone of digit" EXACT [OBOL:automatic] synonym: "hand digit 4 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 4 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 4 th finger" EXACT [OBOL:automatic] synonym: "long bone of digit of fourth finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 4" EXACT [OBOL:automatic] synonym: "phalanx of ring finger" EXACT [FMA:35486] synonym: "ring finger phalanx" EXACT [FMA:35486] xref: MA:0001392 ! hand digit 4 phalanx xref: ncithesaurus:Hand_Digit_4_Phalanx ! Hand Digit 4 Phalanx xref: FMA:35486 ! Phalanx of ring finger intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003624 ! manual digit 4 xref: SCTID:361787005 ! Entire phalanx of ring finger xref: EMAPA:19119 ! phalanx of digit 4 of fore-paw relationship: develops_from UBERON:0010678 ! finger 4 phalanx cartilage condensation synonym: "hand digit 4 phalanx" EXACT [MA:0001392] xref: UMLS:C1708316 [Term] id: UBERON:0003639 name: manual digit 5 phalanx def: "A phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit 5 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5 phalanx" EXACT [OBOL:accepted] synonym: "phalanx of manual digitus minimus" EXACT [OBOL:automatic] synonym: "5 th digit of hand phalanx" EXACT [OBOL:automatic] synonym: "5 th finger phalanx" EXACT [OBOL:automatic] synonym: "fifth finger phalanx" EXACT [OBOL:automatic] synonym: "phalanx of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 5 th finger" EXACT [OBOL:automatic] synonym: "phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 5" EXACT [OBOL:automatic] synonym: "5 th digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "5 th digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "5 th finger digit long bone" EXACT [OBOL:automatic] synonym: "5 th finger long bone of digit" EXACT [OBOL:automatic] synonym: "digit long bone of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 5 th finger" EXACT [OBOL:automatic] synonym: "digit long bone of fifth finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 5" EXACT [OBOL:automatic] synonym: "fifth finger digit long bone" EXACT [OBOL:automatic] synonym: "fifth finger long bone of digit" EXACT [OBOL:automatic] synonym: "hand digit 5 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 5 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 5 th finger" EXACT [OBOL:automatic] synonym: "long bone of digit of fifth finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 5" EXACT [OBOL:automatic] synonym: "phalanx of little finger" EXACT [FMA:35489] synonym: "little finger phalanx" EXACT [FMA:35489] synonym: "phalanx of fifth digit of hand" EXACT [FMA:35489] xref: MA:0001393 ! hand digit 5 phalanx xref: ncithesaurus:Hand_Digit_5_Phalanx ! Hand Digit 5 Phalanx xref: FMA:35489 ! Phalanx of little finger intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003625 ! manual digit 5 xref: SCTID:361789008 ! Entire phalanx of little finger xref: EMAPA:19121 ! phalanx of digit 5 of fore-paw relationship: develops_from UBERON:0010679 ! finger 5 phalanx cartilage condensation synonym: "hand digit 5 phalanx" EXACT [MA:0001393] xref: UMLS:C1708317 [Term] id: UBERON:0001449 name: phalanx of pes alt_id: UBERON:0004272 def: "A phalanx that is part of a hindlimb autopod[Automatically generated definition]." [UBERON:cjm, Wikipedia:Phalanges_of_the_foot] synonym: "pedal phalanx" EXACT [] synonym: "foot phalanx" EXACT [MA:0000305] synonym: "phalanges of hind digit" RELATED PLURAL [AAO:0000930] synonym: "phalanx of hind digit" EXACT [] synonym: "phalanx of pes" EXACT [] synonym: "digitus pedis phalanx" EXACT [OBOL:automatic] synonym: "foot digit phalanx" EXACT [OBOL:automatic] synonym: "phalanx of digit of foot" EXACT [OBOL:automatic] synonym: "phalanx of digitus pedis" EXACT [OBOL:automatic] synonym: "phalanx of foot digit" EXACT [OBOL:automatic] synonym: "toe phalanx" EXACT [OBOL:automatic] synonym: "digital bone of pes" EXACT [OBOL:automatic] synonym: "phalanx of toe" EXACT [FMA:24493] xref: FMA:24493 ! Phalanx of toe xref: MA:0000305 ! foot phalanx xref: AAO:0000930 ! phalanges of hind digit intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0010696 ! skeleton of posterior acropodium xref: ncithesaurus:Foot_Phalanx ! Foot Phalanx xref: ncithesaurus:Phalanx_of_the_Foot ! Phalanx of the Foot xref: SCTID:302533005 ! Entire phalanx of toe relationship: develops_from UBERON:0010685 ! toe phalanx cartilage condensation property_value: external_definition "Dumb-bell shaped bones of endochondral origin with cartilaginous epiphyses that make the five digits of the pes. The terminal phalanges are much smaller than the proximal and penultimate phalanges. The typical phalangeal formula of the pes, in a medial to lateral sequence, is 2(1)-2-3-4(3)-3(2).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000930", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0584876 [Term] id: UBERON:0003640 name: pedal digit 1 phalanx def: "A phalanx that is part of a foot digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit 1 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 phalanx" EXACT [OBOL:accepted] synonym: "hallux phalanx" EXACT [OBOL:automatic] synonym: "phalanx of foot digit 1" EXACT [OBOL:automatic] synonym: "phalanx of hallux" EXACT [OBOL:automatic] synonym: "digit long bone of foot digit 1" EXACT [OBOL:automatic] synonym: "digit long bone of hallux" EXACT [OBOL:automatic] synonym: "foot digit 1 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 1 long bone of digit" EXACT [OBOL:automatic] synonym: "hallux digit long bone" EXACT [OBOL:automatic] synonym: "hallux long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of foot digit 1" EXACT [OBOL:automatic] synonym: "long bone of digit of hallux" EXACT [OBOL:automatic] synonym: "phalanx of big toe" EXACT [FMA:32884] synonym: "big toe phalanx" EXACT [FMA:32884] synonym: "phalanx of first digit of foot" EXACT [FMA:32884] synonym: "phalanx of great toe" EXACT [FMA:32884] xref: MA:0001381 ! foot digit 1 phalanx xref: ncithesaurus:Foot_Digit_1_Phalanx ! Foot Digit 1 Phalanx xref: FMA:32884 ! Phalanx of big toe intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003631 ! pedal digit 1 xref: SCTID:361798006 ! Entire phalanx of great toe xref: EMAPA:19124 ! phalanx of digit 1 of hind-paw relationship: develops_from UBERON:0010680 ! toe 1 phalanx cartilage condensation synonym: "foot digit 1 phalanx" EXACT [MA:0001381] xref: UMLS:C1708080 [Term] id: UBERON:0003641 name: pedal digit 2 phalanx def: "A phalanx that is part of a foot digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit 2 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 phalanx" EXACT [OBOL:accepted] synonym: "phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "digit long bone of foot digit 2" EXACT [OBOL:automatic] synonym: "foot digit 2 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 2 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of foot digit 2" EXACT [OBOL:automatic] synonym: "phalanx of second toe" EXACT [FMA:32899] synonym: "second toe phalanx" EXACT [FMA:32899] xref: MA:0001382 ! foot digit 2 phalanx xref: ncithesaurus:Foot_Digit_2_Phalanx ! Foot Digit 2 Phalanx xref: FMA:32899 ! Phalanx of second toe intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003632 ! pedal digit 2 xref: SCTID:361800004 ! Entire phalanx of second toe xref: EMAPA:19126 ! phalanx of digit 2 of hind-paw relationship: develops_from UBERON:0010681 ! toe 2 phalanx cartilage condensation synonym: "foot digit 2 phalanx" EXACT [MA:0001382] xref: UMLS:C1708082 [Term] id: UBERON:0003642 name: pedal digit 3 phalanx def: "A phalanx that is part of a foot digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit 3 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 phalanx" EXACT [OBOL:accepted] synonym: "phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "digit long bone of foot digit 3" EXACT [OBOL:automatic] synonym: "foot digit 3 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 3 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of foot digit 3" EXACT [OBOL:automatic] synonym: "phalanx of third toe" EXACT [FMA:32900] synonym: "third toe phalanx" EXACT [FMA:32900] xref: MA:0001383 ! foot digit 3 phalanx xref: ncithesaurus:Foot_Digit_3_Phalanx ! Foot Digit 3 Phalanx xref: FMA:32900 ! Phalanx of third toe intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003633 ! pedal digit 3 xref: SCTID:361802007 ! Entire phalanx of third toe xref: EMAPA:19128 ! phalanx of digit 3 of hind-paw relationship: develops_from UBERON:0010682 ! toe 3 phalanx cartilage condensation synonym: "foot digit 3 phalanx" EXACT [MA:0001383] xref: UMLS:C1708084 [Term] id: UBERON:0003862 name: pedal digit 4 phalanx def: "A phalanx that is part of a foot digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit 4 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 phalanx" EXACT [OBOL:accepted] synonym: "phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "digit long bone of foot digit 4" EXACT [OBOL:automatic] synonym: "foot digit 4 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 4 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of foot digit 4" EXACT [OBOL:automatic] synonym: "phalanx of fourth toe" EXACT [FMA:32901] synonym: "fourth toe phalanx" EXACT [FMA:32901] xref: MA:0001384 ! foot digit 4 phalanx xref: ncithesaurus:Foot_Digit_4_Phalanx ! Foot Digit 4 Phalanx xref: FMA:32901 ! Phalanx of fourth toe intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003634 ! pedal digit 4 xref: SCTID:361804008 ! Entire phalanx of fourth toe xref: EMAPA:19130 ! phalanx of digit 4 of hind-paw relationship: develops_from UBERON:0010683 ! toe 4 phalanx cartilage condensation synonym: "foot digit 4 phalanx" EXACT [MA:0001384] xref: UMLS:C1708086 [Term] id: UBERON:0003863 name: pedal digit 5 phalanx def: "A phalanx that is part of a foot digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit 5 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 phalanx" EXACT [OBOL:accepted] synonym: "phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "digit long bone of foot digit 5" EXACT [OBOL:automatic] synonym: "foot digit 5 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 5 long bone of digit" EXACT [OBOL:automatic] synonym: "long bone of digit of foot digit 5" EXACT [OBOL:automatic] synonym: "phalanx of little toe" EXACT [FMA:32902] synonym: "little toe phalanx" EXACT [FMA:32902] synonym: "phalanx of fifth digit of foot" EXACT [FMA:32902] synonym: "phalanx of fifth toe" EXACT [FMA:32902] xref: MA:0001385 ! foot digit 5 phalanx xref: ncithesaurus:Foot_Digit_5_Phalanx ! Foot Digit 5 Phalanx xref: FMA:32902 ! Phalanx of little toe intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003635 ! pedal digit 5 xref: SCTID:361806005 ! Entire phalanx of little toe xref: EMAPA:19132 ! phalanx of digit 5 of hind-paw relationship: develops_from UBERON:0010684 ! toe 5 phalanx cartilage condensation synonym: "foot digit 5 phalanx" EXACT [MA:0001385] xref: UMLS:C1708088 [Term] id: UBERON:0010586 ! finger phalanx pre-cartilage condensation name: manual digit phalanx pre-cartilage condensation synonym: "hand digit phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005257 ! manual digit mesenchyme xref: VHOG:0000954 ! hand phalanx pre-cartilage condensation synonym: "hand phalanx pre-cartilage condensation" EXACT [VHOG:0000954] synonym: "forelimb phalanx pre-cartilage condensation" EXACT [] synonym: "manus phalanx pre-cartilage condensation" EXACT [] def: "A pre-cartilage condensation that is part of a manual digit mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010575 name: manual digit 1 phalanx pre-cartilage condensation synonym: "hand digit 1 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0010564 ! finger 1 mesenchyme xref: EHDAA2:0000516 ! finger 1 phalanx pre-cartilage condensation xref: EMAPA:17715 ! phalanx pre-cartilage condensation of mesenchyme of digit 1 of fore-paw def: "A pre-cartilage condensation that is part of a manual digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010576 name: manual digit 2 phalanx pre-cartilage condensation synonym: "hand digit 2 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005692 ! finger 2 mesenchyme xref: EHDAA2:0000522 ! finger 2 phalanx pre-cartilage condensation xref: EMAPA:17717 ! phalanx pre-cartilage condensation of mesenchyme of digit 2 of fore-paw def: "A pre-cartilage condensation that is part of a manual digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010577 name: manual digit 3 phalanx pre-cartilage condensation synonym: "hand digit 3 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005693 ! finger 3 mesenchyme xref: EHDAA2:0000528 ! finger 3 phalanx pre-cartilage condensation xref: EMAPA:17719 ! phalanx pre-cartilage condensation of mesenchyme of digit 3 of fore-paw def: "A pre-cartilage condensation that is part of a manual digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010578 name: manual digit 4 phalanx pre-cartilage condensation synonym: "hand digit 4 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005694 ! finger 4 mesenchyme xref: EHDAA2:0000534 ! finger 4 phalanx pre-cartilage condensation xref: EMAPA:17721 ! phalanx pre-cartilage condensation of mesenchyme of digit 4 of fore-paw def: "A pre-cartilage condensation that is part of a manual digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010579 name: manual digit 5 phalanx pre-cartilage condensation synonym: "hand digit 5 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005695 ! finger 5 mesenchyme xref: EHDAA2:0000540 ! finger 5 phalanx pre-cartilage condensation xref: EMAPA:17723 ! phalanx pre-cartilage condensation of mesenchyme of digit 5 of fore-paw def: "A pre-cartilage condensation that is part of a manual digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010585 name: pedal digit phalanx pre-cartilage condensation synonym: "foot digit phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005255 ! pedal digit mesenchyme xref: VHOG:0000952 ! foot phalanx pre-cartilage condensation synonym: "foot phalanx pre-cartilage condensation" EXACT [VHOG:0000952] synonym: "hindlimb phalanx pre-cartilage condensation" EXACT [] synonym: "pes phalanx pre-cartilage condensation" EXACT [] def: "A pre-cartilage condensation that is part of a pedal digit mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010580 name: pedal digit 1 phalanx pre-cartilage condensation synonym: "foot digit 1 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0010562 ! toe 1 mesenchyme xref: EHDAA2:0002041 ! toe 1 phalanx pre-cartilage condensation xref: EMAPA:17726 ! phalanx pre-cartilage condensation of mesenchyme of digit 1 of hind-paw def: "A pre-cartilage condensation that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010581 name: pedal digit 2 phalanx pre-cartilage condensation synonym: "foot digit 2 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005696 ! toe 2 mesenchyme xref: EHDAA2:0002046 ! toe 2 phalanx pre-cartilage condensation xref: EMAPA:17728 ! phalanx pre-cartilage condensation of mesenchyme of digit 2 of hind-paw def: "A pre-cartilage condensation that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010582 name: pedal digit 3 phalanx pre-cartilage condensation synonym: "foot digit 3 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005697 ! toe 3 mesenchyme xref: EHDAA2:0002051 ! toe 3 phalanx pre-cartilage condensation xref: EMAPA:17730 ! phalanx pre-cartilage condensation of mesenchyme of digit 3 of hind-paw def: "A pre-cartilage condensation that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010583 name: pedal digit 4 phalanx pre-cartilage condensation synonym: "foot digit 4 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005698 ! toe 4 mesenchyme xref: EHDAA2:0002056 ! toe 4 phalanx pre-cartilage condensation xref: EMAPA:17732 ! phalanx pre-cartilage condensation of mesenchyme of digit 4 of hind-paw def: "A pre-cartilage condensation that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010584 name: pedal digit 5 phalanx pre-cartilage condensation synonym: "foot digit 5 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0005699 ! toe 5 mesenchyme xref: EHDAA2:0002061 ! toe 5 phalanx pre-cartilage condensation xref: EMAPA:17734 ! phalanx pre-cartilage condensation of mesenchyme of digit 5 of hind-paw def: "A pre-cartilage condensation that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010700 ! phalanx pre-cartilage condensation name: phalanx pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0010702 ! digit mesenchyme relationship: part_of UBERON:0006717 ! autopodial skeleton def: "A pre-cartilage condensation that is part of a digit mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010701 ! phalanx cartilage condensation name: phalanx cartilage condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0010702 ! digit mesenchyme relationship: part_of UBERON:0006717 ! autopodial skeleton relationship: develops_from UBERON:0010700 ! phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a digit mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010702 ! digit mesenchyme name: digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002544 ! digit def: "Mesenchyme that is part of a digit." [OBOL:automatic] [Term] id: UBERON:0010686 name: manual digit phalanx cartilage condensation synonym: "hand digit phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005257 ! manual digit mesenchyme relationship: develops_from UBERON:0010586 ! finger phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a manual digit mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010675 name: manual digit 1 phalanx cartilage condensation synonym: "hand digit 1 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0010564 ! finger 1 mesenchyme xref: EMAPA:18066 ! phalanx cartilage condensation of mesenchyme of digit 1 of fore-paw relationship: develops_from UBERON:0010575 ! finger 1 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a manual digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010676 name: manual digit 2 phalanx cartilage condensation synonym: "hand digit 2 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005692 ! finger 2 mesenchyme xref: EMAPA:18071 ! phalanx cartilage condensation of mesenchyme of digit 2 of fore-paw relationship: develops_from UBERON:0010576 ! finger 2 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a manual digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010677 name: manual digit 3 phalanx cartilage condensation synonym: "hand digit 3 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005693 ! finger 3 mesenchyme xref: EMAPA:18076 ! phalanx cartilage condensation of mesenchyme of digit 3 of fore-paw relationship: develops_from UBERON:0010577 ! finger 3 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a manual digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010678 name: manual digit 4 phalanx cartilage condensation synonym: "hand digit 4 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005694 ! finger 4 mesenchyme xref: EMAPA:18081 ! phalanx cartilage condensation of mesenchyme of digit 4 of fore-paw relationship: develops_from UBERON:0010578 ! finger 4 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a manual digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010679 name: manual digit 5 phalanx cartilage condensation synonym: "hand digit 5 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005695 ! finger 5 mesenchyme xref: EMAPA:18086 ! phalanx cartilage condensation of mesenchyme of digit 5 of fore-paw relationship: develops_from UBERON:0010579 ! finger 5 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a manual digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010685 name: pedal digit phalanx cartilage condensation synonym: "foot digit phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005255 ! pedal digit mesenchyme relationship: develops_from UBERON:0010585 ! toe phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a pedal digit mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010680 name: pedal digit 1 phalanx cartilage condensation synonym: "foot digit 1 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0010562 ! toe 1 mesenchyme xref: EMAPA:18107 ! phalanx cartilage condensation of mesenchyme of digit 1 of hind-paw relationship: develops_from UBERON:0010580 ! toe 1 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010681 name: pedal digit 2 phalanx cartilage condensation synonym: "foot digit 2 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005696 ! toe 2 mesenchyme xref: EMAPA:18112 ! phalanx cartilage condensation of mesenchyme of digit 2 of hind-paw relationship: develops_from UBERON:0010581 ! toe 2 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010682 name: pedal digit 3 phalanx cartilage condensation synonym: "foot digit 3 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005697 ! toe 3 mesenchyme xref: EMAPA:18117 ! phalanx cartilage condensation of mesenchyme of digit 3 of hind-paw relationship: develops_from UBERON:0010582 ! toe 3 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010683 name: pedal digit 4 phalanx cartilage condensation synonym: "foot digit 4 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005698 ! toe 4 mesenchyme xref: EMAPA:18122 ! phalanx cartilage condensation of mesenchyme of digit 4 of hind-paw relationship: develops_from UBERON:0010583 ! toe 4 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010684 name: pedal digit 5 phalanx cartilage condensation synonym: "foot digit 5 phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 phalanx cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: part_of UBERON:0005699 ! toe 5 mesenchyme xref: EMAPA:18127 ! phalanx cartilage condensation of mesenchyme of digit 5 of hind-paw relationship: develops_from UBERON:0010584 ! toe 5 phalanx pre-cartilage condensation def: "A cartilaginous condensation that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0003643 name: respiratory system arterial blood vessel def: "An arterial blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: MA:0001800 ! respiratory system arterial blood vessel intersection_of: UBERON:0003509 ! arterial blood vessel intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003644 name: kidney arterial blood vessel def: "An arterial blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] xref: MA:0002578 ! kidney arterial blood vessel intersection_of: UBERON:0003509 ! arterial blood vessel intersection_of: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0003645 name: metacarpal bone of digit 1 def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 1." [OBOL:automatic] synonym: "pollex ; digitus primus [ I ] metacarpal" EXACT [OBOL:automatic] synonym: "pollex ; digitus primus [ I ] metacarpal bone" EXACT [OBOL:automatic] synonym: "first digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "first digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "hand digit 1 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 1 metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone of Pollex ; Digitus primus [ I ]" EXACT [OBOL:automatic] synonym: "metacarpal bone of first digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 1" EXACT [OBOL:automatic] synonym: "metacarpal bone of thumb" EXACT [OBOL:automatic] synonym: "metacarpal of Pollex ; Digitus primus [ I ]" EXACT [OBOL:automatic] synonym: "metacarpal of first digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 1" EXACT [OBOL:automatic] synonym: "metacarpal of thumb" EXACT [OBOL:automatic] synonym: "thumb metacarpal" EXACT [OBOL:automatic] synonym: "thumb metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone digit 1" EXACT [MA:0001364] synonym: "first metacarpal bone" EXACT [FMA:23899] synonym: "metacarpal I" EXACT [FMA:23899] synonym: "metacarpal 1" EXACT [] synonym: "finger 1 metacarpus" EXACT [] synonym: "manual digit 1 metacarpus" EXACT [] xref: FMA:23899 ! First metacarpal bone xref: MA:0001364 ! metacarpal bone digit 1 is_a: UBERON:0013581 ! metapodium bone 1 intersection_of: UBERON:0002374 ! metacarpal bone intersection_of: distally_connected_to UBERON:0004338 ! proximal phalanx of manual digit 1 xref: ncithesaurus:Metacarpal_Bone_Digit_1 ! Metacarpal Bone Digit 1 xref: SCTID:181973009 ! Entire first metacarpal xref: AAO:0010616 ! metacarpal I xref: EMAPA:19112 ! metacarpus of digit 1 of fore-paw relationship: develops_from UBERON:0010570 ! finger 1 metacarpus cartilage condensation property_value: ray_number "1" xsd:nonNegativeInteger property_value: external_definition "The first metacarpal bone or the metacarpal bone of the thumb is the first bone of the thumb. It is connected to the trapezium of the carpus at the first carpometacarpal joint and to the proximal thumb phalanx at the first metacarpophalangeal joint[Wikipedia:First_metacarpal_bone]." xsd:string {source="Wikipedia:First_metacarpal_bone"} xref: UMLS:C1708987 [Term] id: UBERON:0003646 name: metacarpal bone of digit 2 synonym: "2 nd digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "2 nd digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "2 nd finger metacarpal" EXACT [OBOL:automatic] synonym: "2 nd finger metacarpal bone" EXACT [OBOL:automatic] synonym: "hand digit 2 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 2 metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 2 nd finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 2" EXACT [OBOL:automatic] synonym: "metacarpal bone of second finger" EXACT [OBOL:automatic] synonym: "metacarpal of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 2 nd finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 2" EXACT [OBOL:automatic] synonym: "metacarpal of second finger" EXACT [OBOL:automatic] synonym: "second finger metacarpal" EXACT [OBOL:automatic] synonym: "second finger metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone digit 2" EXACT [MA:0001365] synonym: "second metacarpal bone" EXACT [FMA:23900] synonym: "metacarpal II" EXACT [FMA:23900] synonym: "metacarpal 2" EXACT [] synonym: "finger 2 metacarpus" EXACT [] synonym: "manual digit 2 metacarpus" EXACT [] xref: FMA:23900 ! Second metacarpal bone [SYNONYM: "Metacarpal II" (exact)] xref: MA:0001365 ! metacarpal bone digit 2 is_a: UBERON:0013582 ! metapodium bone 2 intersection_of: UBERON:0002374 ! metacarpal bone intersection_of: distally_connected_to UBERON:0004328 ! proximal phalanx of manual digit 2 xref: ncithesaurus:Metacarpal_Bone_Digit_2 ! Metacarpal Bone Digit 2 xref: SCTID:263399007 ! Entire second metacarpal xref: AAO:0000853 ! metacarpal II xref: EMAPA:19114 ! metacarpus of digit 2 of fore-paw relationship: develops_from UBERON:0010571 ! finger 2 metacarpus cartilage condensation property_value: ray_number "2" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with the prepollex and carpal 2(1) or carpal 2+3(1+2) proximally and with the proximal phalanx of digit II(I) distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000853", date_retrieved="2012-06-20", source="AAO:LAP"} def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 2." [OBOL:automatic] xref: UMLS:C1708988 [Term] id: UBERON:0003647 name: metacarpal bone of digit 3 def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 3[Automatically generated definition]." [OBOL:automatic, Wikipedia:Third_metacarpal_bone] synonym: "3 rd digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "3 rd digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "3 rd finger metacarpal" EXACT [OBOL:automatic] synonym: "3 rd finger metacarpal bone" EXACT [OBOL:automatic] synonym: "hand digit 3 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 3 metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 3 rd finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 3" EXACT [OBOL:automatic] synonym: "metacarpal bone of third finger" EXACT [OBOL:automatic] synonym: "metacarpal of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 3 rd finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 3" EXACT [OBOL:automatic] synonym: "metacarpal of third finger" EXACT [OBOL:automatic] synonym: "third finger metacarpal" EXACT [OBOL:automatic] synonym: "third finger metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone digit 3" EXACT [MA:0001366] synonym: "third metacarpal bone" EXACT [FMA:23901] synonym: "metacarpal III" EXACT [FMA:23901] synonym: "metacarpal 3" EXACT [] synonym: "finger 3 metacarpus" EXACT [] synonym: "manual digit 3 metacarpus" EXACT [] synonym: "cannon bone" NARROW SENSU [UBERON:cjm] xref: FMA:23901 ! Third metacarpal bone xref: MA:0001366 ! metacarpal bone digit 3 is_a: UBERON:0013583 ! metapodium bone 3 intersection_of: UBERON:0002374 ! metacarpal bone intersection_of: distally_connected_to UBERON:0004329 ! proximal phalanx of manual digit 3 xref: ncithesaurus:Metacarpal_Bone_Digit_3 ! Metacarpal Bone Digit 3 xref: SCTID:263400000 ! Entire third metacarpal xref: AAO:0000854 ! metacarpal III xref: EMAPA:19116 ! metacarpus of digit 3 of fore-paw relationship: develops_from UBERON:0010572 ! finger 3 metacarpus cartilage condensation property_value: ray_number "3" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with carpal 3(2) proximally and with the proximal phalanx of digit III(II) distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000854", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The third metacarpal bone (metacarpal bone of the middle finger) is a little smaller than the second. The dorsal aspect of its base presents on its radial side a pyramidal eminence, the styloid process, which extends upward behind the capitate; immediately distal to this is a rough surface for the attachment of the extensor carpi radialis brevis muscle. The carpal articular facet is concave behind, flat in front, and articulates with the capitate. On the radial side is a smooth, concave facet for articulation with the second metacarpal, and on the ulnar side two small oval facets for the fourth metacarpal[Wikipedia:Third_metacarpal_bone]." xsd:string {source="Wikipedia:Third_metacarpal_bone"} xref: UMLS:C1708989 [Term] id: UBERON:0003648 name: metacarpal bone of digit 4 def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 4." [OBOL:automatic] synonym: "4 th digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "4 th digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "4 th finger metacarpal" EXACT [OBOL:automatic] synonym: "4 th finger metacarpal bone" EXACT [OBOL:automatic] synonym: "fourth finger metacarpal" EXACT [OBOL:automatic] synonym: "fourth finger metacarpal bone" EXACT [OBOL:automatic] synonym: "hand digit 4 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 4 metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 4 th finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of fourth finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 4" EXACT [OBOL:automatic] synonym: "metacarpal of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 4 th finger" EXACT [OBOL:automatic] synonym: "metacarpal of fourth finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 4" EXACT [OBOL:automatic] synonym: "metacarpal bone digit 4" EXACT [MA:0001367] synonym: "fourth metacarpal bone" EXACT [FMA:23902] synonym: "metacarpal IV" EXACT [FMA:23902] synonym: "metacarpal 4" EXACT [] synonym: "finger 4 metacarpus" EXACT [] synonym: "manual digit 4 metacarpus" EXACT [] xref: FMA:23902 ! Fourth metacarpal bone [SYNONYM: "Metacarpal IV" (exact)] xref: MA:0001367 ! metacarpal bone digit 4 is_a: UBERON:0013584 ! metapodium bone 4 intersection_of: UBERON:0002374 ! metacarpal bone intersection_of: distally_connected_to UBERON:0004330 ! proximal phalanx of manual digit 4 xref: ncithesaurus:Metacarpal_Bone_Digit_4 ! Metacarpal Bone Digit 4 xref: SCTID:263401001 ! Entire fourth metacarpal xref: AAO:0010615 ! metacarpal IV xref: EMAPA:19118 ! metacarpus of digit 4 of fore-paw relationship: develops_from UBERON:0010573 ! finger 4 metacarpus cartilage condensation property_value: ray_number "4" xsd:nonNegativeInteger property_value: external_definition "The fourth metacarpal bone (metacarpal bone of the ring finger) is shorter and smaller than the third. The base is small and quadrilateral; its superior surface presents two facets, a large one medially for articulation with the hamate, and a small one laterally for the capitate. On the radial side are two oval facets, for articulation with the third metacarpal; and on the ulnar side a single concave facet, for the fifth metacarpal[Wikipedia:Fourth_metacarpal_bone]." xsd:string {source="Wikipedia:Fourth_metacarpal_bone"} xref: UMLS:C1708990 [Term] id: UBERON:0003649 name: metacarpal bone of digit 5 def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 5." [OBOL:automatic] comment: note FMA also has FMA:36782 ! Bone of fifth metacarpal bone synonym: "5 th digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "5 th digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "5 th finger metacarpal" EXACT [OBOL:automatic] synonym: "5 th finger metacarpal bone" EXACT [OBOL:automatic] synonym: "fifth finger metacarpal" EXACT [OBOL:automatic] synonym: "fifth finger metacarpal bone" EXACT [OBOL:automatic] synonym: "hand digit 5 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 5 metacarpal bone" EXACT [OBOL:automatic] synonym: "metacarpal bone of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 5 th finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of fifth finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 5" EXACT [OBOL:automatic] synonym: "metacarpal of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 5 th finger" EXACT [OBOL:automatic] synonym: "metacarpal of fifth finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 5" EXACT [OBOL:automatic] synonym: "metacarpal bone digit 5" EXACT [MA:0001368] synonym: "fifth metacarpal bone" EXACT [FMA:23903] synonym: "metacarpal V" EXACT [] synonym: "metacarpal 5" EXACT [] synonym: "finger 5 metacarpus" EXACT [] synonym: "manual digit 5 metacarpus" EXACT [] xref: FMA:23903 ! Fifth metacarpal bone xref: MA:0001368 ! metacarpal bone digit 5 is_a: UBERON:0013585 ! metapodium bone 5 intersection_of: UBERON:0002374 ! metacarpal bone intersection_of: distally_connected_to UBERON:0004331 ! proximal phalanx of manual digit 5 xref: ncithesaurus:Metacarpal_Bone_Digit_5 ! Metacarpal Bone Digit 5 xref: SCTID:263402008 ! Entire fifth metacarpal xref: AAO:0000855 ! metacarpal V xref: EMAPA:19120 ! metacarpus of digit 5 of fore-paw relationship: develops_from UBERON:0010574 ! finger 5 metacarpus cartilage condensation property_value: ray_number "5" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell shaped bones of endochondral origin with cartilaginous epiphyses that articulates with carpal 5(4) proximally and with the proximal phalanx of digit V(IV) distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000855", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The fifth metacarpal bone (metacarpal bone of the little finger or pinky finger) is the most lateral metacarpal[Wikipedia:Fifth_metacarpal_bone]." xsd:string {source="Wikipedia:Fifth_metacarpal_bone"} xref: UMLS:C1711224 [Term] id: UBERON:0003650 name: metatarsal bone of digit 1 def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 1." [OBOL:automatic] synonym: "foot digit 1 metatarsal bone" EXACT [OBOL:automatic] synonym: "hallux metatarsal bone" EXACT [OBOL:automatic] synonym: "metatarsal bone of foot digit 1" EXACT [OBOL:automatic] synonym: "metatarsal bone of hallux" EXACT [OBOL:automatic] synonym: "metatarsal bone digit 1" EXACT [MA:0001369] synonym: "first metatarsal bone" EXACT [FMA:24502] synonym: "metatarsal I" EXACT [AAO:0000925] synonym: "metatarsal 1" EXACT [] synonym: "toe 1 metatarsal" EXACT [] synonym: "toe 1 metatarsus" EXACT [] xref: FMA:24502 ! First metatarsal bone xref: MA:0001369 ! metatarsal bone digit 1 xref: AAO:0000925 ! metatarsal I is_a: UBERON:0013581 ! metapodium bone 1 intersection_of: UBERON:0001448 ! metatarsal bone intersection_of: distally_connected_to UBERON:0004332 ! proximal phalanx of pedal digit 1 xref: ncithesaurus:Metatarsal_Bone_Digit_1 ! Metatarsal Bone Digit 1 xref: SCTID:182121005 ! Entire first metatarsal relationship: develops_from UBERON:0010557 ! toe 1 metatarsal cartilage condensation xref: EMAPA:19123 ! metatarsus of digit 1 of hind-paw property_value: ray_number "1" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with the prepollex and tarsal 1 proximally and with the proximal phalanx of digit I distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000925", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The first metatarsal bone is the bone in the body of the foot just behind the big toe. It is remarkable for its great thickness, and is the shortest of the metatarsal bones. The body is strong, and of well-marked prismoid form. The base presents, as a rule, no articular facets on its sides, but occasionally on the lateral side there is an oval facet, by which it articulates with the second metatarsal. Its proximal articular surface is of large size and kidney-shaped; its circumference is grooved, for the tarsometatarsal ligaments, and medially gives insertion to part of the tendon of the Tibialis anterior; its plantar angle presents a rough oval prominence for the insertion of the tendon of the Peronæus longus. The head is large; on its plantar surface are two grooved facets, on which glide sesamoid bones; the facets are separated by a smooth elevation[Wikipedia:First_metatarsal_bone]." xsd:string {source="Wikipedia:First_metatarsal_bone"} xref: UMLS:C1708999 [Term] id: UBERON:0003651 name: metatarsal bone of digit 2 synonym: "foot digit 2 metatarsal bone" EXACT [OBOL:automatic] synonym: "metatarsal bone of foot digit 2" EXACT [OBOL:automatic] synonym: "metatarsal bone digit 2" EXACT [MA:0001370] synonym: "second metatarsal bone" EXACT [FMA:24503] synonym: "metatarsal II" EXACT [AAO:0000926] synonym: "metatarsal 2" EXACT [] synonym: "toe 2 metatarsal" EXACT [] synonym: "toe 2 metatarsus" EXACT [] xref: FMA:24503 ! Second metatarsal bone xref: MA:0001370 ! metatarsal bone digit 2 xref: AAO:0000926 ! metatarsal II is_a: UBERON:0013582 ! metapodium bone 2 intersection_of: UBERON:0001448 ! metatarsal bone intersection_of: distally_connected_to UBERON:0004333 ! proximal phalanx of pedal digit 2 xref: ncithesaurus:Metatarsal_Bone_Digit_2 ! Metatarsal Bone Digit 2 xref: SCTID:182128004 ! Entire second metatarsal relationship: develops_from UBERON:0010558 ! toe 2 metatarsal cartilage condensation xref: EMAPA:19125 ! metatarsus of digit 2 of hind-paw property_value: ray_number "2" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 2 proximally and with the proximal phalanx of digit II distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000926", date_retrieved="2012-06-20", source="AAO:LAP"} def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 2." [OBOL:automatic] xref: UMLS:C1709000 [Term] id: UBERON:0003652 name: metatarsal bone of digit 3 def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 3[Automatically generated definition]." [OBOL:automatic, Wikipedia:Third_metatarsal_bone] synonym: "foot digit 3 metatarsal bone" EXACT [OBOL:automatic] synonym: "metatarsal bone of foot digit 3" EXACT [OBOL:automatic] synonym: "metatarsal bone digit 3" EXACT [MA:0001371] synonym: "third metatarsal bone" EXACT [FMA:24504] synonym: "metatarsal III" EXACT [AAO:0000927] synonym: "metatarsal 3" EXACT [] synonym: "toe 3 metatarsal" EXACT [] synonym: "toe 3 metatarsus" EXACT [] synonym: "cannon bone" NARROW SENSU [UBERON:cjm] xref: FMA:24504 ! Third metatarsal bone xref: MA:0001371 ! metatarsal bone digit 3 xref: AAO:0000927 ! metatarsal III is_a: UBERON:0013583 ! metapodium bone 3 intersection_of: UBERON:0001448 ! metatarsal bone intersection_of: distally_connected_to UBERON:0004334 ! proximal phalanx of pedal digit 3 xref: ncithesaurus:Metatarsal_Bone_Digit_3 ! Metatarsal Bone Digit 3 xref: SCTID:182134006 ! Entire third metatarsal relationship: develops_from UBERON:0010559 ! toe 3 metatarsal cartilage condensation xref: EMAPA:19127 ! metatarsus of digit 3 of hind-paw property_value: ray_number "3" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 3 proximally and with the proximal phalanx of digit III distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000927", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The third metatarsal bone articulates proximally, by means of a triangular smooth surface, with the third cuneiform; medially, by two facets, with the second metatarsal; and laterally, by a single facet, with the fourth metatarsal. This last facet is situated at the dorsal angle of the base[Wikipedia:Third_metatarsal_bone]." xsd:string {source="Wikipedia:Third_metatarsal_bone"} xref: UMLS:C1709001 [Term] id: UBERON:0003653 name: metatarsal bone of digit 4 def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 4." [OBOL:automatic] synonym: "foot digit 4 metatarsal bone" EXACT [OBOL:automatic] synonym: "metatarsal bone of foot digit 4" EXACT [OBOL:automatic] synonym: "metatarsal bone digit 4" EXACT [MA:0001372] synonym: "fourth metatarsal bone" EXACT [FMA:24505] synonym: "metatarsal IV" EXACT [AAO:0000928] synonym: "metatarsal 4" EXACT [] synonym: "toe 4 metatarsal" EXACT [] synonym: "toe 4 metatarsus" EXACT [] xref: FMA:24505 ! Fourth metatarsal bone xref: MA:0001372 ! metatarsal bone digit 4 xref: AAO:0000928 ! metatarsal IV is_a: UBERON:0013584 ! metapodium bone 4 intersection_of: UBERON:0001448 ! metatarsal bone intersection_of: distally_connected_to UBERON:0004335 ! proximal phalanx of pedal digit 4 xref: ncithesaurus:Metatarsal_Bone_Digit_4 ! Metatarsal Bone Digit 4 xref: SCTID:182139001 ! Entire fourth metatarsal relationship: develops_from UBERON:0010560 ! toe 4 metatarsal cartilage condensation xref: EMAPA:19129 ! metatarsus of digit 4 of hind-paw property_value: ray_number "4" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 4 or the distal head of the tibiale-fibulare proximally and with the proximal phalanx of digit IV distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000928", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The fourth metatarsal bone is smaller in size than the third; its base presents an oblique quadrilateral surface for articulation with the cuboid; a smooth facet on the medial side, divided by a ridge into an anterior portion for articulation with the third metatarsal, and a posterior portion for articulation with the third cuneiform; on the lateral side a single facet, for articulation with the fifth metatarsal[Wikipedia:Fourth_metatarsal_bone]." xsd:string {source="Wikipedia:Fourth_metatarsal_bone"} xref: UMLS:C1709002 [Term] id: UBERON:0003654 name: metatarsal bone of digit 5 def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 5." [OBOL:automatic] synonym: "foot digit 5 metatarsal bone" EXACT [OBOL:automatic] synonym: "metatarsal bone of foot digit 5" EXACT [OBOL:automatic] synonym: "metatarsal bone digit 5" EXACT [MA:0001373] synonym: "fifth metatarsal bone" EXACT [FMA:24506] synonym: "metatarsal V" EXACT [AAO:0000929] synonym: "metatarsal 5" EXACT [] synonym: "toe 5 metatarsal" EXACT [] synonym: "toe 5 metatarsus" EXACT [] xref: FMA:24506 ! Fifth metatarsal bone xref: MA:0001373 ! metatarsal bone digit 5 xref: AAO:0000929 ! metatarsal V is_a: UBERON:0013585 ! metapodium bone 5 intersection_of: UBERON:0001448 ! metatarsal bone intersection_of: distally_connected_to UBERON:0004336 ! proximal phalanx of pedal digit 5 xref: ncithesaurus:Metatarsal_Bone_Digit_5 ! Metatarsal Bone Digit 5 xref: SCTID:182144008 ! Entire fifth metatarsal relationship: develops_from UBERON:0010561 ! toe 5 metatarsal cartilage condensation xref: EMAPA:19131 ! metatarsus of digit 5 of hind-paw property_value: ray_number "5" xsd:nonNegativeInteger property_value: external_definition "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 5 or the distal head of the tibiale-fibulare proximally and with the proximal phalanx of digit V distally.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000929", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The fifth metatarsal bone is recognized by a rough eminence, the tuberosity, on the lateral side of its base. The base articulates behind, by a triangular surface cut obliquely in a transverse direction, with the cuboid; and medially, with the fourth metatarsal. On the medial part of its dorsal surface is inserted the tendon of the Peronæus tertius and on the dorsal surface of the tuberosity that of the Peronæus brevis. A strong band of the plantar aponeurosis connects the projecting part of the tuberosity with the lateral process of the tuberosity of the calcaneus. The plantar surface of the base is grooved for the tendon of the Abductor digiti quinti, and gives origin to the Flexor digiti quinti brevis. The base of the metatarsal is often injured and a particularly notorious fracture is the Jones fracture. When the tuberosity is broken, it is called a pseudo-Jones fracture or a dancer's fracture. This is a common fracture of the fifth metatarsal. Stress fractures are common in the fifth metatarsal among athletes[Wikipedia:Fifth_metatarsal_bone]." xsd:string {source="Wikipedia:Fifth_metatarsal_bone"} xref: UMLS:C1709003 [Term] id: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation name: pedal digit metatarsal pre-cartilage condensation synonym: "foot digit metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] is_a: UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0005255 ! pedal digit mesenchyme xref: VHOG:0000948 ! metatarsus pre-cartilage condensation synonym: "metatarsus pre-cartilage condensation" EXACT [VHOG:0000948] synonym: "metatarsal bone pre-cartilage condensation" EXACT [] [Term] id: UBERON:0010547 name: pedal digit 1 metatarsal pre-cartilage condensation synonym: "foot digit 1 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation intersection_of: part_of UBERON:0010562 ! toe 1 mesenchyme xref: EHDAA2:0002040 ! toe 1 metatarsal pre-cartilage condensation synonym: "toe 1 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002040] xref: EMAPA:17725 ! metatarsus pre-cartilage condensation of mesenchyme of digit 1 of hind-paw def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010548 name: pedal digit 2 metatarsal pre-cartilage condensation synonym: "foot digit 2 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation intersection_of: part_of UBERON:0005696 ! toe 2 mesenchyme xref: EHDAA2:0002045 ! toe 2 metatarsal pre-cartilage condensation synonym: "toe 2 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002045] xref: EMAPA:17727 ! metatarsus pre-cartilage condensation of mesenchyme of digit 2 of hind-paw def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010549 name: pedal digit 3 metatarsal pre-cartilage condensation synonym: "foot digit 3 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation intersection_of: part_of UBERON:0005697 ! toe 3 mesenchyme xref: EHDAA2:0002050 ! toe 3 metatarsal pre-cartilage condensation synonym: "toe 3 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002050] xref: EMAPA:17729 ! metatarsus pre-cartilage condensation of mesenchyme of digit 3 of hind-paw def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010550 name: pedal digit 4 metatarsal pre-cartilage condensation synonym: "foot digit 4 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation intersection_of: part_of UBERON:0005698 ! toe 4 mesenchyme xref: EHDAA2:0002055 ! toe 4 metatarsal pre-cartilage condensation synonym: "toe 4 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002055] xref: EMAPA:17731 ! metatarsus pre-cartilage condensation of mesenchyme of digit 4 of hind-paw def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010551 name: pedal digit 5 metatarsal pre-cartilage condensation synonym: "foot digit 5 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation intersection_of: part_of UBERON:0005699 ! toe 5 mesenchyme xref: EHDAA2:0002060 ! toe 5 metatarsal pre-cartilage condensation synonym: "toe 5 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002060] xref: EMAPA:17733 ! metatarsus pre-cartilage condensation of mesenchyme of digit 5 of hind-paw def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010697 ! pedal digit metatarsal cartilage condensation name: pedal digit metatarsal cartilage condensation synonym: "foot digit metatarsal cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit metatarsal cartilage condensation" EXACT [OBOL:accepted] is_a: UBERON:0005863 ! cartilaginous condensation relationship: part_of UBERON:0005255 ! pedal digit mesenchyme [Term] id: UBERON:0010557 name: pedal digit 1 metatarsal cartilage condensation synonym: "foot digit 1 metatarsal cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 metatarsal cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010697 ! pedal digit metatarsal cartilage condensation intersection_of: part_of UBERON:0010562 ! toe 1 mesenchyme relationship: develops_from UBERON:0010547 ! toe 1 metatarsal pre-cartilage condensation xref: EMAPA:18106 ! metatarsus cartilage condensation of mesenchyme of digit 1 of hind-paw synonym: "toe 1 metatarsal cartilage condensation" EXACT [] def: "A pedal digit metatarsal cartilage condensation that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010558 name: pedal digit 2 metatarsal cartilage condensation synonym: "foot digit 2 metatarsal cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 metatarsal cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010697 ! pedal digit metatarsal cartilage condensation intersection_of: part_of UBERON:0005696 ! toe 2 mesenchyme relationship: develops_from UBERON:0010548 ! toe 2 metatarsal pre-cartilage condensation xref: EMAPA:18111 ! metatarsus cartilage condensation of mesenchyme of digit 2 of hind-paw synonym: "toe 2 metatarsal cartilage condensation" EXACT [] def: "A pedal digit metatarsal cartilage condensation that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010559 name: pedal digit 3 metatarsal cartilage condensation synonym: "foot digit 3 metatarsal cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 metatarsal cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010697 ! pedal digit metatarsal cartilage condensation intersection_of: part_of UBERON:0005697 ! toe 3 mesenchyme relationship: develops_from UBERON:0010549 ! toe 3 metatarsal pre-cartilage condensation xref: EMAPA:18116 ! metatarsus cartilage condensation of mesenchyme of digit 3 of hind-paw synonym: "toe 3 metatarsal cartilage condensation" EXACT [] def: "A pedal digit metatarsal cartilage condensation that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010560 name: pedal digit 4 metatarsal cartilage condensation synonym: "foot digit 4 metatarsal cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 metatarsal cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010697 ! pedal digit metatarsal cartilage condensation intersection_of: part_of UBERON:0005698 ! toe 4 mesenchyme relationship: develops_from UBERON:0010550 ! toe 4 metatarsal pre-cartilage condensation xref: EMAPA:18121 ! metatarsus cartilage condensation of mesenchyme of digit 4 of hind-paw synonym: "toe 4 metatarsal cartilage condensation" EXACT [] def: "A pedal digit metatarsal cartilage condensation that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010561 name: pedal digit 5 metatarsal cartilage condensation synonym: "foot digit 5 metatarsal cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 metatarsal cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010697 ! pedal digit metatarsal cartilage condensation intersection_of: part_of UBERON:0005699 ! toe 5 mesenchyme relationship: develops_from UBERON:0010551 ! toe 5 metatarsal pre-cartilage condensation xref: EMAPA:18126 ! metatarsus cartilage condensation of mesenchyme of digit 5 of hind-paw synonym: "toe 5 metatarsal cartilage condensation" EXACT [] def: "A pedal digit metatarsal cartilage condensation that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation name: manual digit metacarpus pre-cartilage condensation synonym: "hand digit metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] is_a: UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0005257 ! manual digit mesenchyme xref: VHOG:0000953 ! metacarpus pre-cartilage condensation synonym: "metacarpus pre-cartilage condensation" EXACT [VHOG:0000953] synonym: "metacarpal bone pre-cartilage condensation" EXACT [VHOG:0000953] synonym: "metacarpal pre-cartilage condensation" EXACT [] [Term] id: UBERON:0010565 name: manual digit 1 metacarpus pre-cartilage condensation synonym: "hand digit 1 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation intersection_of: part_of UBERON:0010564 ! finger 1 mesenchyme xref: EHDAA2:0000515 ! finger 1 metacarpus pre-cartilage condensation synonym: "finger 1 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000515] synonym: "metacarpal 1 pre-cartilage condensation" EXACT [] xref: EMAPA:17714 ! metacarpus pre-cartilage condensation of mesenchyme of digit 1 of fore-paw def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010566 name: manual digit 2 metacarpus pre-cartilage condensation synonym: "hand digit 2 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation intersection_of: part_of UBERON:0005692 ! finger 2 mesenchyme xref: EHDAA2:0000521 ! finger 2 metacarpus pre-cartilage condensation synonym: "finger 2 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000521] synonym: "metacarpal 2 pre-cartilage condensation" EXACT [] xref: EMAPA:17716 ! metacarpus pre-cartilage condensation of mesenchyme of digit 2 of fore-paw def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010567 name: manual digit 3 metacarpus pre-cartilage condensation synonym: "hand digit 3 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation intersection_of: part_of UBERON:0005693 ! finger 3 mesenchyme xref: EHDAA2:0000527 ! finger 3 metacarpus pre-cartilage condensation synonym: "finger 3 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000527] synonym: "metacarpal 3 pre-cartilage condensation" EXACT [] xref: EMAPA:17718 ! metacarpus pre-cartilage condensation of mesenchyme of digit 3 of fore-paw def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010568 name: manual digit 4 metacarpus pre-cartilage condensation synonym: "hand digit 4 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation intersection_of: part_of UBERON:0005694 ! finger 4 mesenchyme xref: EHDAA2:0000533 ! finger 4 metacarpus pre-cartilage condensation synonym: "finger 4 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000533] synonym: "metacarpal 4 pre-cartilage condensation" EXACT [] xref: EMAPA:17720 ! metacarpus pre-cartilage condensation of mesenchyme of digit 4 of fore-paw def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010569 name: manual digit 5 metacarpus pre-cartilage condensation synonym: "hand digit 5 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation intersection_of: part_of UBERON:0005695 ! finger 5 mesenchyme xref: EHDAA2:0000539 ! finger 5 metacarpus pre-cartilage condensation synonym: "finger 5 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000539] synonym: "metacarpal 5 pre-cartilage condensation" EXACT [] xref: EMAPA:17722 ! metacarpus pre-cartilage condensation of mesenchyme of digit 5 of fore-paw def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010699 ! manual digit metacarpus cartilage condensation name: manual digit metacarpus cartilage condensation synonym: "hand digit metacarpus cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit metacarpus cartilage condensation" EXACT [OBOL:accepted] is_a: UBERON:0005863 ! cartilaginous condensation synonym: "finger metacarpus cartilage condensation" EXACT [] synonym: "metacarpus cartilage condensation" EXACT [] synonym: "metacarpal cartilage condensation" EXACT [] relationship: part_of UBERON:0005257 ! manual digit mesenchyme relationship: develops_from UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation [Term] id: UBERON:0010570 name: manual digit 1 metacarpus cartilage condensation synonym: "hand digit 1 metacarpus cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1 metacarpus cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010699 ! manual digit metacarpus cartilage condensation intersection_of: part_of UBERON:0010564 ! finger 1 mesenchyme relationship: develops_from UBERON:0010565 ! finger 1 metacarpus pre-cartilage condensation xref: EHDAA2:0000514 ! finger 1 metacarpus cartilage condensation synonym: "finger 1 metacarpus cartilage condensation" EXACT [EHDAA2:0000514] synonym: "metacarpus 1 cartilage condensation" EXACT [] xref: EMAPA:18065 ! metacarpus cartilage condensation of mesenchyme of digit 1 of fore-paw def: "A manual digit metacarpus cartilage condensation that is part of a manual digit 1 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010571 name: manual digit 2 metacarpus cartilage condensation synonym: "hand digit 2 metacarpus cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2 metacarpus cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010699 ! manual digit metacarpus cartilage condensation intersection_of: part_of UBERON:0005692 ! finger 2 mesenchyme relationship: develops_from UBERON:0010566 ! finger 2 metacarpus pre-cartilage condensation xref: EHDAA2:0000520 ! finger 2 metacarpus cartilage condensation synonym: "finger 2 metacarpus cartilage condensation" EXACT [EHDAA2:0000520] synonym: "metacarpus 2 cartilage condensation" EXACT [] xref: EMAPA:18070 ! metacarpus cartilage condensation of mesenchyme of digit 2 of fore-paw def: "A manual digit metacarpus cartilage condensation that is part of a manual digit 2 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010572 name: manual digit 3 metacarpus cartilage condensation synonym: "hand digit 3 metacarpus cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3 metacarpus cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010699 ! manual digit metacarpus cartilage condensation intersection_of: part_of UBERON:0005693 ! finger 3 mesenchyme relationship: develops_from UBERON:0010567 ! finger 3 metacarpus pre-cartilage condensation xref: EHDAA2:0000526 ! finger 3 metacarpus cartilage condensation synonym: "finger 3 metacarpus cartilage condensation" EXACT [EHDAA2:0000526] synonym: "metacarpus 3 cartilage condensation" EXACT [] xref: EMAPA:18075 ! metacarpus cartilage condensation of mesenchyme of digit 3 of fore-paw def: "A manual digit metacarpus cartilage condensation that is part of a manual digit 3 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010573 name: manual digit 4 metacarpus cartilage condensation synonym: "hand digit 4 metacarpus cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4 metacarpus cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010699 ! manual digit metacarpus cartilage condensation intersection_of: part_of UBERON:0005694 ! finger 4 mesenchyme relationship: develops_from UBERON:0010568 ! finger 4 metacarpus pre-cartilage condensation xref: EHDAA2:0000532 ! finger 4 metacarpus cartilage condensation synonym: "finger 4 metacarpus cartilage condensation" EXACT [EHDAA2:0000532] synonym: "metacarpus 4 cartilage condensation" EXACT [] xref: EMAPA:18080 ! metacarpus cartilage condensation of mesenchyme of digit 4 of fore-paw def: "A manual digit metacarpus cartilage condensation that is part of a manual digit 4 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010574 name: manual digit 5 metacarpus cartilage condensation synonym: "hand digit 5 metacarpus cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5 metacarpus cartilage condensation" EXACT [OBOL:accepted] intersection_of: UBERON:0010699 ! manual digit metacarpus cartilage condensation intersection_of: part_of UBERON:0005695 ! finger 5 mesenchyme relationship: develops_from UBERON:0010569 ! finger 5 metacarpus pre-cartilage condensation xref: EHDAA2:0000538 ! finger 5 metacarpus cartilage condensation synonym: "finger 5 metacarpus cartilage condensation" EXACT [EHDAA2:0000538] synonym: "metacarpus 5 cartilage condensation" EXACT [] xref: EMAPA:18085 ! metacarpus cartilage condensation of mesenchyme of digit 5 of fore-paw def: "A manual digit metacarpus cartilage condensation that is part of a manual digit 5 mesenchyme." [OBOL:automatic] [Term] id: UBERON:0003658 name: hip muscle def: "A muscle organ that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "hip muscle organ" EXACT [OBOL:automatic] synonym: "hip region muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of hip" EXACT [OBOL:automatic] synonym: "muscle organ of hip region" EXACT [OBOL:automatic] synonym: "muscle organ of regio coxae" EXACT [OBOL:automatic] synonym: "regio coxae muscle organ" EXACT [OBOL:automatic] xref: MA:0000657 ! hip muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001464 ! hip [Term] id: UBERON:0003659 name: pedal digit muscle def: "A muscle organ that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit muscle" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit muscle" EXACT [OBOL:accepted] synonym: "digit of foot muscle organ" EXACT [OBOL:automatic] synonym: "digitus pedis muscle organ" EXACT [OBOL:automatic] synonym: "foot digit muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of digit of foot" EXACT [OBOL:automatic] synonym: "muscle organ of digitus pedis" EXACT [OBOL:automatic] synonym: "muscle organ of foot digit" EXACT [OBOL:automatic] synonym: "muscle organ of toe" EXACT [OBOL:automatic] synonym: "toe muscle organ" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "muscle organ of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit muscle organ" EXACT [OBOL:automatic] xref: MA:0000648 ! foot digit muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001466 ! pedal digit synonym: "foot digit muscle" EXACT [MA:0000648] [Term] id: UBERON:0003660 name: eyelid muscle synonym: "blepharon muscle organ" EXACT [OBOL:automatic] synonym: "eyelid muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of blepharon" EXACT [OBOL:automatic] synonym: "muscle organ of eyelid" EXACT [OBOL:automatic] xref: MA:0000269 ! eyelid muscle xref: ncithesaurus:Eyelid_Muscle ! Eyelid Muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0001711 ! eyelid xref: UMLS:C1707990 [Term] id: UBERON:0006318 name: orbitalis muscle def: "An orbitalis muscle is a rudimentary nonstriated muscle (smooth muscle) that crosses from the infraorbital groove and sphenomaxillary fissure and intimately united with the periosteum of the orbit. It is often called Muller's muscle. One characteristic of Horner's Syndrome is enophthalmos (retraction of the eyeball into the orbit due to paralysis of the orbitalis muscle that spans the inferior orbital fissure). Its function is eyeball protrusion." [Wikipedia:Orbitalis_muscle] comment: subclass of 'muscle layer' in FMA synonym: "orbitalis" RELATED [Wikipedia:Orbitalis_muscle] synonym: "orbital muscle" EXACT [FMA:49034] synonym: "orbital muscle of muller" EXACT [FMA:49034] synonym: "orbitalis" EXACT [FMA:49034] xref: MA:0001274 ! orbitalis muscle xref: FMA:49034 ! orbitalis is_a: UBERON:0003660 {source="MA"} ! eyelid muscle is_a: UBERON:0006660 {source="FMA"} ! muscle layer relationship: part_of UBERON:0000019 {source="FMA"} ! camera-type eye synonym: "musculus orbitalis" EXACT LATIN [FMA:TA, FMA:49034] xref: ncithesaurus:Orbitalis_Muscle ! Orbitalis Muscle xref: SCTID:368790005 ! Entire orbitalis muscle synonym: "musculus orbitalis" RELATED LATIN [Wikipedia:Orbitalis_muscle] xref: UMLS:C0229105 [Term] id: UBERON:0003661 name: limb muscle def: "A muscle organ that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "limb muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of limb" EXACT [OBOL:automatic] xref: MA:0000692 ! limb muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0010890 name: pelvic complex muscle def: "Muscles of the pelvic girdle, hindlimb or pelvic fin." [UBERON:cjm] intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0010709 ! pelvic complex synonym: "lower limb muscle" RELATED INCONSISTENT [FMA:9622] synonym: "muscle of lower limb" RELATED INCONSISTENT [FMA:9622] synonym: "pelvic girdle or hind limb muscle" NARROW [UBERON:cjm] synonym: "pelvic girdle or posterior limb muscle" NARROW [UBERON:cjm] synonym: "pelvic girdle or posterior limb muscle" NARROW [UBERON:cjm] synonym: "muscle of pelvic girdle and leg" RELATED [] synonym: "pelvic girdle and hind limb muscles" EXACT [AAO:0000218] xref: AAO:0000218 ! pelvic girdle and hind limb muscles xref: FMA:9622 ! muscle of lower limb xref: MA:0000663 ! hindlimb muscle property_value: external_definition "Muscles of the pelvic girdle, thigh, leg (crus), and foot (pes).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000218", date_retrieved="2012-06-20", source="AAO:EJS"} [Term] id: UBERON:0003663 name: hindlimb muscle def: "A muscle organ that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb muscle organ" EXACT [OBOL:automatic] synonym: "hindlimb muscle organ" EXACT [OBOL:automatic] synonym: "inferior member muscle organ" EXACT [OBOL:automatic] synonym: "lower extremity muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of hind limb" EXACT [OBOL:automatic] synonym: "muscle organ of hindlimb" EXACT [OBOL:automatic] synonym: "muscle organ of inferior member" EXACT [OBOL:automatic] synonym: "muscle organ of lower extremity" EXACT [OBOL:automatic] synonym: "muscle of posterior limb" EXACT [UBERON:cjm] synonym: "free lower limb muscle" EXACT [FMA:37368] xref: EFO:0001928 ! hindlimb muscle xref: AAO:0000222 ! hindlimb muscles xref: FMA:37368 ! Muscle of free lower limb intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002103 ! hindlimb synonym: "muscle of free lower limb" EXACT [FMA:37368] [Term] id: UBERON:0003664 name: manual digit muscle def: "A muscle organ that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit muscle" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit muscle" EXACT [OBOL:accepted] synonym: "digit of hand muscle organ" EXACT [OBOL:automatic] synonym: "digitus manus muscle organ" EXACT [OBOL:automatic] synonym: "finger muscle organ" EXACT [OBOL:automatic] synonym: "hand digit muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of digit of hand" EXACT [OBOL:automatic] synonym: "muscle organ of digitus manus" EXACT [OBOL:automatic] synonym: "muscle organ of finger" EXACT [OBOL:automatic] synonym: "muscle organ of hand digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "muscle organ of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit muscle organ" EXACT [OBOL:automatic] xref: MA:0000624 ! hand digit muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002389 ! manual digit synonym: "hand digit muscle" EXACT [MA:0000624] [Term] id: UBERON:0003665 name: tail muscle def: "A muscle organ that attaches to a tail vertebra [Automatically generated definition]." [OBOL:automatic] synonym: "muscle organ of post-vent region" EXACT [OBOL:automatic] synonym: "muscle organ of tail" EXACT [OBOL:automatic] synonym: "post-vent region muscle organ" EXACT [OBOL:automatic] synonym: "tail muscle organ" EXACT [OBOL:automatic] synonym: "caudal muscle" EXACT [] xref: MA:0000699 ! tail muscle xref: BTO:0001905 ! tail muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0001095 ! caudal vertebra relationship: overlaps UBERON:0007812 ! post-anal tail xref: SCTID:113230005 ! Muscle of tail xref: AAO:0000081 ! caudal muscles [Term] id: UBERON:0013221 name: caudofemoralis def: "The caudofemoralis (from the latin cauda, tail and femur, thighbone) is a muscle found in the pelvic limb of mostly all animals possessing a tail, since it is a synapomorphy appeared on the Archosauria clade. It is thus found in felids (cats) and Mustela (\"Weasels\"), but also on crocodiles and birds." [Wikipedia:Caudofemoralis] comment: Action: The Caudofemoralis acts to flex the tail laterally to its respective side when the pelvic limb is bearing weight. When the pelvic limb is lifted off the ground, contraction of the Caudofemoralis causes the limb to abduct and the shank to extend by extending the hip joint (acetabulofemoral or coxofemoral joint) synonym: "caudofemoralis muscle" EXACT [] is_a: UBERON:0001630 ! muscle organ relationship: has_muscle_origin UBERON:0001095 ! caudal vertebra [Term] id: UBERON:0003668 ! synovial bursa name: synovial bursa def: "a small fluid-filled sac lined by synovial membrane with an inner capillary layer of slimy fluid. It provides a cushion between bones and tendons and/or muscles around a joint. This helps to reduce friction between the bones and allows free movement. Bursae are filled with synovial fluid and are found around most major joints of the body." [Wikipedia:Synovial_bursa] synonym: "bursa" BROAD [FMA:9692] xref: FMA:9692 ! Synovial bursa xref: GAID:252 ! synovial bursa xref: ncithesaurus:Synovial_Bursa ! Synovial Bursa xref: galen:Bursa ! bursa xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/Gray350.png/200px-Gray350.png xref: MESH:A02.835.583.156 ! synovial bursa is_a: UBERON:0000062 ! organ relationship: located_in UBERON:0002018 ! synovial membrane of synovial joint xref: SCTID:182483003 ! Entire bursa subset: organ_slim synonym: "bursa synovialis" RELATED LATIN [Wikipedia:Synovial_bursa] xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/Gray350.png xref: UMLS:C0006441 [Term] id: UBERON:0003903 ! bursa of Fabricius name: bursa of Fabricius def: "an epithelial and lymphoid organ that develops as a dorsal diverticulum of the proctodeal region of the cloaca in birds. The luminal (interior) surface of the bursa is plicated with as many as 15 primary and 7 secondary plicae or folds. These plicae have hundreds of bursal follicles containing follicle-associated epithelial cells, lymphocytes, macrophages, and plasma cells. Lymphoid stem cells migrate from the fetal liver to the bursa during ontogeny. In the bursa, these stem cells acquire the characteristics of mature, immunocompetent B cells[WP]. The bursa is an organ found in birds involved in B cell differentiation[GO]." [Wikipedia:Bursa_of_Fabricius, GO:0048540] xref: GAID:1205 ! bursa of fabricius xref: BTO:0001699 ! bursa of Fabricius xref: MESH:A13.163 ! bursa of fabricius xref: SCTID:86689007 ! Bursa of Fabricius structure is_a: UBERON:0011510 ! cloacal bursa is_a: UBERON:0004177 ! hemopoietic organ relationship: site_of GO:0030097 {source="Wikipedia"} ! hemopoiesis relationship: site_of GO:0030183 ! B cell differentiation relationship: only_in_taxon NCBITaxon:8457 ! Sauropsida subset: organ_slim [Term] id: UBERON:0003904 ! bursal plica name: bursal plica def: "Follicle containing part of bursa of Fabricius. The luminal (interior) surface of the bursa is plicated with as many as 15 primary and 7 secondary plicae or folds. These plicae have hundreds of bursal follicles containing follicle-associated epithelial cells, lymphocytes, macrophages, and plasma cells. Lymphoid stem cells migrate from the fetal liver to the bursa during ontogeny. In the bursa, these stem cells acquire the characteristics of mature, immunocompetent B cells[WP]." [GOC:cjm] synonym: "bursal fold" EXACT [] synonym: "bursal plicae" EXACT PLURAL [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0003903 ! bursa of Fabricius [Term] id: UBERON:0003905 ! bursal follicle name: bursal follicle def: "Follicle within the plicae of bursa of Fabricius." [GOC:cjm] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0003904 ! bursal plica [Term] id: UBERON:0011236 ! deep fascia name: deep fascia def: "Deep fascia (or \"investing fascia\") is a layer of fascia which can surround individual muscles, and divide groups of muscles into compartments. This is the dense fibrous connective tissue that interpenetrates and surrounds the muscles, bones, nerves and blood vessels of the body. It provides connection and communication in the form of aponeuroses, ligaments, tendons, retinacula, joint capsules, and septa. The deep fasciae envelop all bone; cartilage, and blood vessels and become specialized in muscles and nerves. The high density of collagen fibers is what gives the deep fascia its strength and integrity. The amount of elastin fiber determines how much extensibility and resilience it will have." [Wikipedia:Deep_fascia] synonym: "deep investing fascia" RELATED [Wikipedia:Deep_fascia] synonym: "investing fascia" RELATED [Wikipedia:Deep_fascia] synonym: "fascia profunda" RELATED LATIN [Wikipedia:Deep_fascia] is_a: UBERON:0008982 ! fascia xref: ncithesaurus:Deep_Fascia ! deep fascia xref: FMA:27935 ! Investing fascia xref: UMLS:C1511746 [Term] id: UBERON:0011237 name: visceral fascia def: "Visceral fascia suspends the organs within their cavities and wraps them in layers of connective tissue membranes. Each of the organs is covered in a double layer of fascia; these layers are separated by a thin serous membrane. The outermost wall of the organ is known as the parietal layer The skin of the organ is known as the visceral layer. The organs have specialized names for their visceral fasciae. In the brain, they are known as meninges; in the heart they are known as pericardia; in the lungs, they are known as pleura; and in the abdomen, they are known as peritonea." [Wikipedia:Visceral_fascia] synonym: "parietal fascia" RELATED [Wikipedia:Visceral_fascia] is_a: UBERON:0008982 ! fascia xref: FMA:76754 ! visceral fascia [Term] id: UBERON:0003669 name: fascia lata def: "The fascia lata is the deep fascia of the thigh. [WP,unvetted]." [Wikipedia:Fascia_lata] xref: FMA:13902 ! Fascia lata xref: GAID:117 ! fascia lata xref: ncithesaurus:Fascia_Lata ! Fascia Lata xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Gray431.png/200px-Gray431.png xref: MESH:A02.340.424 ! fascia lata is_a: UBERON:0011236 ! deep fascia relationship: part_of UBERON:0000376 ! hindlimb stylopod xref: SCTID:361911008 ! Entire fascia lata xref: http://upload.wikimedia.org/wikipedia/commons/e/e7/Gray431.png xref: UMLS:C0015642 [Term] id: UBERON:0003670 ! smegma name: smegma def: "a combination of exfoliated (shed) epithelial cells, transudated skin oils, and moisture. It occurs in both female and male mammalian genitalia[WP]." [Wikipedia:Smegma] xref: FMA:19656 ! Smegma xref: GAID:1170 ! smegma xref: ncithesaurus:Smegma ! Smegma xref: MESH:A12.200.769 ! smegma is_a: UBERON:0000456 ! bodily secretion relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia xref: UMLS:C0037359 [Term] id: UBERON:0003673 name: ligamentum flavum synonym: "flaval ligament" RELATED [GAID:126] xref: FMA:13423 ! Ligamentum flavum xref: GAID:126 ! ligamentum flavum xref: ncithesaurus:Ligamentum_Flavum ! Ligamentum Flavum xref: MESH:A02.513.514.287 ! ligamentum flavum is_a: UBERON:0000211 ! ligament xref: SCTID:244598002 ! Entire ligamentum flavum xref: UMLS:C0206327 [Term] id: UBERON:0003674 name: cuspid def: "In mammalian oral anatomy, the canine teeth, also called cuspids, dogteeth, fangs, or (in the case of those of the upper jaw) eye teeth, are relatively long, pointed teeth. However, they can appear more flattened, causing them to resemble incisors and leading them to be called incisiform. They evolved and are used primarily for firmly holding food in order to tear it apart, and occasionally as weapons. They are often the largest teeth in a mammal's mouth. Most species that develop them normally have four per individual, two in the upper jaw and two in the lower, separated within each jaw by its incisors; humans and dogs are examples. In most animals, canines are the anterior-most teeth in the maxillary bone. The four canines in humans are the two maxillary canines and the two mandibular canines." [Wikipedia:Canine_tooth] synonym: "canine %28tooth%29" RELATED [Wikipedia:Canine_tooth] synonym: "canine eminence" RELATED [Wikipedia:Canine_tooth] synonym: "canine teeth" RELATED PLURAL [Wikipedia:Canine_tooth] synonym: "dens caninus" RELATED [Wikipedia:Canine_tooth] synonym: "dogtooth %28anatomy%29" RELATED [Wikipedia:Canine_tooth] synonym: "eye teeth" RELATED PLURAL [Wikipedia:Canine_tooth] synonym: "eye tooth" RELATED [Wikipedia:Canine_tooth] synonym: "eyeteeth" RELATED PLURAL [Wikipedia:Canine_tooth] synonym: "eyetooth" RELATED [Wikipedia:Canine_tooth] synonym: "fang" RELATED [Wikipedia:Canine_tooth] synonym: "canine teeth" RELATED PLURAL [GAID:1262] synonym: "canine" BROAD [] synonym: "canine tooth" EXACT [FMA:55636] synonym: "cuspis dentis" EXACT LATIN [FMA:TA, FMA:55636] synonym: "dentes canini" RELATED LATIN [Wikipedia:Canine_tooth] xref: FMA:55636 ! Canine tooth xref: GAID:1262 ! cuspid xref: MESH:A14.254.860.200 ! cuspid is_a: UBERON:0001091 ! tooth relationship: has_part UBERON:0006844 {count="1", editor_notes="cardinality not allowed with transitivity in OWL"} ! cusp of tooth relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia disjoint_from: UBERON:0001098 ! incisor tooth disjoint_from: UBERON:0003655 ! molar tooth disjoint_from: UBERON:0007120 ! premolar tooth xref: ncithesaurus:Canine_Tooth ! Canine Tooth xref: SCTID:88719004 ! Fang xref: http://upload.wikimedia.org/wikipedia/commons/5/57/Azawakh_K9.jpg xref: UMLS:C0010482 [Term] id: UBERON:0013164 ! molariform tooth name: molariform tooth def: "A molar or premolar" [ISBN10:0073040584] synonym: "cheek tooth" RELATED [ISBN10:0073040584] synonym: "molariform" RELATED [ISBN10:0073040584] synonym: "postcanine tooth" EXACT [http://www.termwiki.com/EN:postcanine_teeth] is_a: UBERON:0001091 ! calcareous tooth relationship: has_part UBERON:0006844 ! cusp of tooth [Term] id: UBERON:0003655 name: molar tooth def: "Molars are the rearmost and most complicated kind of tooth in most mammals." [Wikipedia:Molar_(tooth)] comment: Adult humans have twelve molars, in four groups of three at the back of the mouth. The third, rearmost molar in each group is called a wisdom tooth. It is the last tooth to appear, breaking through the surface of the gum at about the age of twenty, although this varies from individual to individual. Ethnicity can also have an impact on the age at which this occurs, with statistical variations between groups. The human mouth contains upper (maxillary) and lower (mandibular) molars. They are: maxillary first molar, maxillary second molar, maxillary third molar, mandibular first molar, mandibular second molar, and mandibular third molar. synonym: "dens molaris" EXACT [Wikipedia:Molar_%28tooth%29] synonym: "molar" RELATED [MA:0000350] synonym: "molaris" EXACT [BTO:0001759] xref: FMA:55638 ! Molar tooth xref: MA:0000350 ! molar xref: ncithesaurus:Molar_Tooth ! Molar Tooth xref: BTO:0001759 ! molaris xref: MESH:A14.254.860.525 ! molar is_a: UBERON:0013164 ! molariform tooth xref: SCTID:362115002 ! Entire molar tooth disjoint_from: UBERON:0001098 ! incisor tooth disjoint_from: UBERON:0003674 ! cuspid disjoint_from: UBERON:0007120 ! premolar tooth xref: UMLS:C0026367 [Term] id: UBERON:0007120 name: premolar tooth def: "The premolar teeth or bicuspids are transitional teeth located between the canine and molar teeth. In humans, there are two premolars per quadrant, making eight premolars total in the mouth. They have at least two cusps. Premolars can be considered as a 'transitional tooth' during chewing, or mastication. It has properties of both the anterior canines and posterior molars, and so food can be transferred from the canines to the premolars and finally to the molars for grinding, instead of directly from the canines to the molars. The premolars in humans are the maxillary first premolar, maxillary second premolar, mandibular first premolar, and the mandibular second premolar. There is always one large buccal cusp, especially so in the mandibular first premolar. The lower second premolar almost always presents with two lingual cusps. Premolar teeth by definition are permanent teeth distal to the canines preceded by deciduous molars. In primitive mammals there are four premolars per quadrant. The most mesial two have been lost in Catarrhines. Paleontologists refer to human premolars as Pm3 and Pm4." [Wikipedia:Premolar] synonym: "secondary premolar tooth" NARROW [FMA:55637] synonym: "bicuspid" RELATED [Wikipedia:Premolar] synonym: "bicuspid teeth" RELATED [Wikipedia:Premolar] synonym: "bicuspid tooth" RELATED [Wikipedia:Premolar] synonym: "bicuspids" RELATED [Wikipedia:Premolar] synonym: "biscuspid" RELATED [Wikipedia:Premolar] synonym: "dens premolaris" RELATED [Wikipedia:Premolar] synonym: "dentes premolares" RELATED [Wikipedia:Premolar] synonym: "mandibular bicuspid" RELATED [Wikipedia:Premolar] synonym: "maxillary bicuspid" RELATED [Wikipedia:Premolar] synonym: "maxillary premolar" RELATED [Wikipedia:Premolar] synonym: "pm3 %28dentistry%29" RELATED [Wikipedia:Premolar] synonym: "pr%c3%a6molares" RELATED [Wikipedia:Premolar] synonym: "praemolares" RELATED [Wikipedia:Premolar] synonym: "premolar teeth" RELATED [Wikipedia:Premolar] synonym: "premolar tooth" RELATED [Wikipedia:Premolar] synonym: "premolars" RELATED [Wikipedia:Premolar] synonym: "premolar" RELATED [Wikipedia:Premolar] synonym: "dentes premolares" RELATED LATIN [Wikipedia:Premolar] xref: FMA:55637 ! premolar tooth xref: MESH:A14.254.860.150 xref: GAID:1261 ! bicuspid is_a: UBERON:0013164 ! molariform tooth relationship: has_part UBERON:0006844 {min_count="1", editor_notes="cardinality not allowed with transitivity in OWL"} ! cusp of tooth disjoint_from: UBERON:0002135 ! mitral valve disjoint_from: UBERON:0001098 ! incisor tooth disjoint_from: UBERON:0003655 ! molar tooth disjoint_from: UBERON:0003674 ! cuspid xref: ncithesaurus:Bicuspid_Tooth ! Bicuspid Tooth xref: SCTID:304572005 ! Entire premolar tooth xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray1003.png xref: UMLS:C1704302 [Term] id: UBERON:0003675 name: tooth crown synonym: "tooth crown" EXACT [FMA:55623] synonym: "crown" RELATED [] synonym: "crown of tooth" EXACT [FMA:55623] synonym: "anatomical crown" EXACT [FMA:55623] synonym: "corona dentis" EXACT [ncithesaurus:Corona_Dentis] xref: FMA:55623 ! Crown of tooth xref: GAID:1275 ! tooth crown xref: MESH:A14.254.900.710 ! tooth crown xref: ncithesaurus:Corona_Dentis ! Crown is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001091 ! tooth xref: SCTID:362106009 ! Entire crown of tooth xref: UMLS:C0226993 [Term] id: UBERON:0003677 name: tooth root synonym: "radix corona" EXACT [FMA:55624] synonym: "tooth root" EXACT [FMA:55624] synonym: "root of tooth" EXACT [FMA:55624] xref: FMA:55624 ! Root of tooth xref: GAID:1280 ! tooth root xref: MESH:A14.254.900.750 ! tooth root is_a: UBERON:0000063 ! organ segment relationship: attaches_to UBERON:0001091 ! tooth relationship: part_of UBERON:0001091 ! tooth xref: SCTID:245728004 ! Entire tooth root [Term] id: UBERON:0003678 name: tooth apex synonym: "apical foramen" RELATED [GAID:1281] synonym: "tooth apex" EXACT [FMA:63000] synonym: "tooth apice" RELATED [GAID:1281] synonym: "apex of tooth" EXACT [FMA:63000] xref: FMA:63000 ! Apex of tooth xref: GAID:1281 ! tooth apex xref: MESH:A14.254.900.750.700 ! tooth apex is_a: UBERON:0000015 ! anatomical boundary relationship: part_of UBERON:0001091 ! tooth [Term] id: UBERON:0013612 name: tooth cingulid def: "A ridge that girdles the base of a lower molar tooth" [http://en.wiktionary.org/wiki/cingulid] synonym: "cingulid of molar tooth" EXACT [] synonym: "cingulid" BROAD [] is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0003667 ! lower jaw molar [Term] id: UBERON:0013613 name: tooth cingulum def: "A ridge that girdles the base of a upper molar tooth" [http://en.wiktionary.org/wiki/cingulum] synonym: "cingulum of molar tooth" EXACT [] synonym: "cingulum" BROAD [] is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0003666 ! upper jaw molar disjoint_from: UBERON:0003961 ! cingulum [Term] id: UBERON:0003679 name: mouth floor synonym: "floor of mouth" EXACT [FMA:86592] synonym: "sublingual region" RELATED [GAID:1283] xref: FMA:86592 ! Floor of mouth xref: GAID:1283 ! mouth floor xref: ncithesaurus:Floor_of_the_Mouth ! Floor of Mouth xref: MESH:A14.549.441 ! mouth floor xref: EFO:0001923 ! floor of mouth is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0000165 ! mouth xref: SCTID:245786002 ! Entire floor of mouth xref: UMLS:C0026638 [Term] id: UBERON:0003682 name: palatal muscle def: "The muscles of the palate are the glossopalatine, palatoglossus, levator palati(ni), musculus uvulae, palatopharyngeus, and tensor palati(ni)." [MESH:A02.633.567.750, Wikipedia:Muscles_of_soft_palate_and_fauces] comment: Editor notes: consider extra class for fauces. AO notes: see also FMA:71438 ! set of muscles of soft palate and fauces synonym: "palatal muscle" EXACT [FMA:46726] synonym: "palate muscle" EXACT [FMA:46726] synonym: "palatine muscle" EXACT [FMA:46726] synonym: "muscle of palate" EXACT [FMA:46726] synonym: "musculi palati mollis et faucium" EXACT [] xref: FMA:46726 ! Muscle of palate xref: GAID:151 ! palatal muscle xref: ncithesaurus:Palatal_Muscle ! Palatal Muscle xref: MESH:A02.633.567.750 ! palatal muscle is_a: UBERON:0002376 ! muscle of head xref: SCTID:244794002 ! Muscle of palate xref: SCTID:73711005 ! Entire muscle of palate AND/OR fauces synonym: "musculi palati mollis et faucium" RELATED LATIN [Wikipedia:Muscles_of_soft_palate_and_fauces] relationship: innervated_by UBERON:0001759 {source="dbpedia", notes="Vagus except tensor veli palatini"} ! vagus nerve xref: http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray1028.png xref: UMLS:C0030213 [Term] id: UBERON:0003683 name: rotator cuff def: "a group of muscles and their tendons that act to stabilize the shoulder. The four muscles of the rotator cuff are over half of the seven scapulohumeral muscles" [Wikipedia:Rotator_cuff] synonym: "musculotendinous cuff" EXACT [FMA:37018] synonym: "rotator cuff" EXACT [FMA:37018] synonym: "tendinous cuff" EXACT [FMA:37018] xref: FMA:37018 ! Tendinous cuff xref: GAID:160 ! rotator cuff xref: ncithesaurus:Rotator_Cuff ! Rotator Cuff xref: MESH:A02.633.567.912 ! rotator cuff is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001467 ! shoulder xref: UMLS:C0085515 [Term] id: UBERON:0003686 name: tooth socket def: "Dental alveolus (plural, alveoli) are sockets in the jaws in which the roots of teeth are held in the alveolar process of maxilla with the periodontal ligament. The lay term for dental alveoli is tooth sockets. A joint that connect the roots of the teeth and the alveolus are called gomphosis (plural gomphoses). In mammals, tooth sockets are found in the maxilla and the mandible. [WP,unvetted]." [Wikipedia:Dental_alveolus] synonym: "alveolus dentali" RELATED [GAID:217] synonym: "alveolus dentalis" RELATED [GAID:217] synonym: "dental alveolus" RELATED [GAID:217] synonym: "dental alveolus" EXACT [FMA:57490] xref: FMA:57490 ! Tooth socket xref: GAID:217 ! tooth socket xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Alveole_zahn.jpg/200px-Alveole_zahn.jpg xref: MESH:A02.835.232.781.324.502.125.800 ! tooth socket is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0004103 {source="MESH-modified"} ! alveolar ridge xref: ncithesaurus:Tooth_Socket ! tooth socket synonym: "alveolus dentalis" RELATED LATIN [Wikipedia:Dental_alveolus] xref: http://upload.wikimedia.org/wikipedia/commons/2/2e/Alveole_zahn.jpg xref: SCTID:288323008 ! Entire alveolus dentalis xref: UMLS:C0227130 [Term] id: UBERON:0003687 name: foramen magnum def: "In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]." [Wikipedia:Foramen_magnum] subset: vertebrate_core xref: FMA:75306 ! Foramen magnum xref: GAID:228 ! foramen magnum xref: ncithesaurus:Foramen_Magnum ! Foramen Magnum xref: OpenCyc:Mx4rwOm-FpwpEbGdrcN5Y29ycA ! foramen magnum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/39/Gray130.png/200px-Gray130.png xref: ZFA:0005387 ! foramen magnum xref: MESH:A02.835.232.781.572.434 ! foramen magnum is_a: UBERON:0005744 ! cranial conduit relationship: located_in UBERON:0001676 ! occipital bone xref: AAO:0010826 ! foramen magnum xref: SCTID:244679008 ! Entire foramen magnum xref: TAO:0002045 ! foramen magnum xref: http://upload.wikimedia.org/wikipedia/commons/3/39/Gray130.png property_value: external_definition "Foramen in the occipital region of neurocranium to allow passage of spinal cord.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002045", date_retrieved="2012-08-14", source="TAO:wd"} xref: UMLS:C0016519 [Term] id: UBERON:0003688 name: omentum xref: FMA:14650 ! Omentum xref: GAID:23 ! omentum xref: ncithesaurus:Omentum ! Omentum xref: galen:Omentum ! omentum xref: MESH:A01.047.025.600.573 ! omentum xref: EV:0100084 ! omentum is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001178 ! visceral peritoneum xref: SCTID:362710002 ! Entire omentum property_value: has_relational_adjective "omental" xsd:string xref: UMLS:C0028977 [Term] id: UBERON:0003689 name: sella turcica def: "The sella turcica is a saddle-shaped depression in the sphenoid bone at the base of the human skull. [WP,unvetted]." [Wikipedia:Sella_turcica] comment: Editor notes: for consistency with FMA we have a separate class for the cavity of the sella turcica synonym: "suprasellar" RELATED [Wikipedia:Sella_turcica] synonym: "turkish saddle" RELATED [Wikipedia:Sella_turcica] xref: FMA:54709 ! Sella turcica xref: GAID:231 ! sella turcica xref: ncithesaurus:Sella_Turcica ! Sella Turcica xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/35/Gray145.png/200px-Gray145.png xref: MESH:A02.835.232.781.802.662 ! sella turcica is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0009639 {source="FMA"} ! body of sphenoid synonym: "Turkey Chair" RELATED LATIN [Wikipedia:Sella_turcica] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Gray145.png xref: SCTID:368554001 ! Entire suprasellar region xref: UMLS:C0036609 [Term] id: UBERON:0006667 name: pituitary fossa synonym: "hypophyseal fossa" EXACT [FMA:54721] synonym: "pituitary fossa" EXACT [FMA:54721] xref: FMA:54721 ! Hypophysial fossa xref: EMAPA:19195 ! pituitary fossa is_a: UBERON:0002553 {source="FMA"} ! anatomical cavity relationship: part_of UBERON:0003689 ! sella turcica xref: SCTID:264194004 ! Entire pituitary fossa synonym: "hypophysial fossa" EXACT [FMA:54721] [Term] id: UBERON:0003690 name: sacrum def: "The sacrum is a large, triangular bone at the base of the spine and at the upper and back part of the pelvic cavity, where it is inserted like a wedge between the two hip bones. Its upper part connects with the last lumbar vertebra, and bottom part with the coccyx (tailbone). In children, it consists of usually five unfused vertebrae which begin to fuse between ages 16-18 and are usually completely fused into a single bone by age 26. It is curved upon itself and placed obliquely (that is, tilted forward). It is kyphotic — that is, concave facing forwards. The base projects forward as the sacral promontory internally, and articulates with the last lumbar vertebra to form the prominent sacrovertebral angle. The central part is curved outward towards the posterior, allowing greater room for the pelvic cavity. [WP,unvetted]." [Wikipedia:Sacrum] synonym: "sacral bone" RELATED [FMA:16202] synonym: "sacrum [sacral vertebrae I-V]" EXACT [FMA:16202] synonym: "sacrum [sacral vertebrae i - v]" EXACT [FMA:16202] synonym: "os sacrum" RELATED [Wikipedia:Sacrum] xref: FMA:16202 ! Sacrum xref: GAID:241 ! sacrum xref: ncithesaurus:Sacrum ! Sacrum xref: galen:Sacrum ! sacrum xref: OpenCyc:Mx4rvmBKnJwpEbGdrcN5Y29ycA ! sacrum xref: AAO:0000552 ! sacrum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ec/Gray95.png/200px-Gray95.png xref: MESH:A02.835.232.834.717 ! sacrum xref: EFO:0003071 ! sacrum is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: part_of UBERON:0005473 {source="FMA"} ! sacral region relationship: part_of UBERON:0001130 {source="FMA"} ! vertebral column relationship: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0001270 {source="FMA"} ! bony pelvis relationship: has_fused_element UBERON:0001094 ! sacral vertebra synonym: "os sacrum [vertebrae sacrales i - v]" EXACT LATIN [FMA:TA, FMA:16202] xref: SCTID:264186006 ! Entire sacrum relationship: anteriorly_connected_to UBERON:0004621 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! lumbar vertebra 5 synonym: "os sacrum" RELATED LATIN [Wikipedia:Sacrum] xref: http://upload.wikimedia.org/wikipedia/commons/e/ec/Gray95.png property_value: external_definition "Enlarged vertebra with transverse processes (diapophyses), and ocassionally ribs, that are modified and elaborated for support of the pelvic girdle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000552", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} property_value: has_relational_adjective "sacral" xsd:string [Term] id: UBERON:0011772 name: lower jaw opening intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0004768 ! bone of lower jaw relationship: part_of UBERON:0004768 ! bone of lower jaw xref: AAO:0000273 ! lower jaw opening def: "An anatomical space that is part of a bone of lower jaw." [OBOL:automatic] [Term] id: UBERON:0011773 name: upper jaw opening intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0011597 ! bone of upper jaw relationship: part_of UBERON:0011597 ! bone of upper jaw xref: AAO:0000621 ! upper jaw opening def: "An anatomical space that is part of a bone of upper jaw." [OBOL:automatic] [Term] id: UBERON:0003691 name: epidural space synonym: "extradural space" EXACT [FMA:71228] xref: FMA:71228 ! Epidural space xref: GAID:243 ! epidural space xref: MESH:A02.835.232.834.803.350 ! epidural space is_a: UBERON:0000464 ! anatomical space synonym: "spatium extradurale" EXACT LATIN [FMA:TA, FMA:71228] xref: SCTID:281866004 ! Entire epidural space [Term] id: UBERON:0003693 name: retroperitoneal space def: "anatomical space in the abdominal cavity behind (retro) the peritoneum. It has no specific delineating anatomical structures. Organs are retroperitoneal if they only have peritoneum on their anterior side." [Wikipedia:Retroperitoneum] synonym: "retroperitoneum" EXACT [FMA:15080] xref: FMA:15080 ! Retroperitoneal space xref: GAID:25 ! retroperitoneal space xref: ncithesaurus:Retroperitoneum ! Retroperitoneum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Gray1126.png/200px-Gray1126.png xref: MESH:A01.047.025.750 ! retroperitoneal space xref: EFO:0002806 ! retroperitoneum is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0003684 ! abdominal cavity xref: SCTID:243983004 ! Entire retroperitoneal space property_value: has_relational_adjective "retroperitoneal" xsd:string xref: UMLS:C0035359 [Term] id: UBERON:0011118 name: tarsometatarsal joint def: "The tarsometatarsal articulations are arthrodial joints in the pes. It is also known as the \"Lisfranc joint\". It is named after 18th-19th century surgeon and gynecologist, Jacques Lisfranc de St. Martin." [Wikipedia:Tarsometatarsal_articulations] synonym: "cuboideometatarsal" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "lisfranc joint" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "tarsometatarsal" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "tarso-metatarsal join" EXACT [] synonym: "tarsometatarsal articulation" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "articulationes tarsometatarsales" RELATED LATIN [Wikipedia:Tarsometatarsal_articulations] xref: FMA:35216 ! tarsometatarsal joint xref: SCTID:182222008 ! Entire tarsometatarsal joint is_a: UBERON:0002217 {source="FMA"} ! synovial joint relationship: part_of UBERON:0002387 ! pes intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001447 ! tarsal bone intersection_of: connects UBERON:0001448 ! metatarsal bone xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray358.png xref: http://upload.wikimedia.org/wikipedia/commons/8/8e/Gray355.png [Term] id: UBERON:0011119 name: carpometacarpal joint def: "The carpometacarpal joints (CMC) are joints in the wrist that articulates the distal row of carpal bones and the proximal bases of the metacarpal bones." [Wikipedia:Carpometacarpal_joint] synonym: "CMJ" BROAD [Wikipedia:Carpometacarpal_joint] synonym: "carpometacarpal" BROAD [Wikipedia:Carpometacarpal_joint] synonym: "carpometacarpal articulation" RELATED [Wikipedia:Carpometacarpal_joint] synonym: "articulationes carpometacarpeæ" EXACT LATIN [Wikipedia:Carpometacarpal_joint] xref: FMA:35287 ! carpometacarpal joint xref: ncithesaurus:Carpometacarpal_Joint ! carpometacarpal joint xref: SCTID:361842002 ! Entire carpometacarpal joint is_a: UBERON:0002217 {source="FMA"} ! synovial joint relationship: part_of UBERON:0002398 ! manus intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001435 ! carpal bone intersection_of: connects UBERON:0002374 ! metacarpal bone xref: http://upload.wikimedia.org/wikipedia/commons/7/7c/Gray335.png xref: UMLS:C0224620 [Term] id: UBERON:0011265 name: carpometacarpal joint of digit 1 def: "A carpometacarpal joint that connects to metacarpal 1. " [Wikipedia:Carpometacarpal_joint#Thumb] comment: Taxon notes: In humans it connects the trapezium to the first metacarpal bone, plays an irreplaceable role in the normal functioning of the thumb. The most important joint connecting the wrist to the metacarpus, osteoarthritis of the TMC is a severely disabling condition; up to twenty times more common among old women than in average[WP] synonym: "carpometacarpal joint of thumb" EXACT [FMA:35421] synonym: "carpometacarpal joint of pollex" EXACT [FMA:35421] synonym: "carpometacarpal joint of the thumb" RELATED [Wikipedia:Carpometacarpal_joint#Thumb] synonym: "trapeziometacarpal joint" RELATED [Wikipedia:Carpometacarpal_joint#Thumb] synonym: "TMJ" RELATED INCONSISTENT [Wikipedia:Carpometacarpal_joint#Thumb] is_a: UBERON:0011965 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="Wikipedia"} ! saddle joint intersection_of: UBERON:0011119 ! carpometacarpal joint intersection_of: connects UBERON:0003645 ! metacarpal bone of digit 1 xref: FMA:35421 ! carpometacarpal joint of thumb xref: SCTID:361843007 ! Entire carpometacarpal joint of thumb [Term] id: UBERON:0009559 ! metacarpal/tarsal-phalangeal joint name: metacarpal/tarsal-phalangeal joint comment: Editor notes: We include these joints as being part of the digits; this is consistent with the FMA, and makes classification easier. Note that digit and metapodial regions are part-disjoint is_a: UBERON:0002217 {source="FMA"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0003656 ! mesopodium bone intersection_of: connects UBERON:0004302 ! proximal phalanx relationship: part_of UBERON:0002544 ! digit synonym: "metapodium-phalanx joint" EXACT [UBERON:cjm] synonym: "metacarpo-tarsophalangeal joint" EXACT [UBERON:cjm] synonym: "fetlock" NARROW SENSU [UBERON:cjm, Wikipedia:Fetlock, NCBITaxon:9788] def: "A skeletal joint that connects a mesopodium bone and connects a proximal phalanx." [OBOL:automatic] [Term] id: UBERON:0003695 name: metacarpophalangeal joint def: "The metacarpophalangeal joints (MCP) are of the condyloid kind, formed by the reception of the rounded heads of the metacarpal bones into shallow cavities on the proximal ends of the first phalanges, with the exception of that of the thumb, which presents more of the characters of a ginglymoid joint. Arthritis of the MCP is a distinguishing feature of Rheumatoid Arthritis, as opposed to the distal interphalangeal joint in osteoarthritis. [WP,unvetted]." [Wikipedia:Metacarpophalangeal_joint] comment: Editor notes: we follow FMA in making these joints part of digits. We include carpometacarpophalangeal joint as a synonym - these joints connect to the carpometacarpus - this is not necessarily inconsistent with the relationship for this class to metacarpal bone, as the carpometacarpus could be considered to have a metacarpal as part synonym: "metacarpal phalangeal joint" RELATED [HP:0004294] synonym: "metacarpal joint" BROAD [FMA:35246] synonym: "MP joint" EXACT [FMA:35246] synonym: "metacarpo-phalangeal joint" EXACT [MA:0000453] synonym: "carpometacarpophalangeal joint" NARROW SENSU [NCBITaxon:8782] xref: FMA:35246 ! Metacarpophalangeal joint xref: GAID:255 ! metacarpophalangeal joint xref: ncithesaurus:Metacarpophalangeal_Joint ! Metacarpophalangeal Joint xref: OpenCyc:Mx4rwNt8wJwpEbGdrcN5Y29ycA ! metacarpophalangeal joint xref: MA:0000453 ! metacarpo-phalangeal joint xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/53/Gray337.png/200px-Gray337.png xref: EMAPA:19302 ! metacarpo-phalangeal xref: MESH:A02.835.583.345.512 ! metacarpophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0002234 ! proximal phalanx of manus relationship: part_of UBERON:0002389 ! manual digit xref: galen:MetacarpoPhalangealJoint xref: SCTID:280995004 ! Entire metacarpophalangeal joint synonym: "articulationes metacarpophalangeae" RELATED LATIN [Wikipedia:Metacarpophalangeal_joint] xref: http://upload.wikimedia.org/wikipedia/commons/5/53/Gray337.png xref: UMLS:C0025525 [Term] id: UBERON:0007735 name: metacarpophalangeal joint of manual digit 1 synonym: "metacarpophalangeal joint of first digit of hand" EXACT [FMA:35249] synonym: "metacarpophalangeal joint of digit 1" EXACT [] synonym: "metacarpo-phalangeal joint of digit 1 of fore-paw" NARROW [EMAPA:25057] xref: EMAPA:25057 ! metacarpo-phalangeal joint of digit 1 of fore-paw xref: FMA:35249 ! metacarpophalangeal joint of thumb intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004338 ! proximal phalanx of manual digit 1 relationship: part_of UBERON:0001463 {source="FMA"} ! manual digit 1 xref: SCTID:361844001 ! Entire metacarpophalangeal joint of thumb synonym: "metacarpophalangeal joint of thumb" NARROW SENSU [NCBITaxon:9606, FMA:35249] def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 1." [OBOL:automatic] [Term] id: UBERON:0007738 name: metacarpophalangeal joint of manual digit 2 synonym: "metacarpophalangeal joint of second digit of hand" EXACT [FMA:35252] synonym: "metacarpophalangeal joint of second finger" EXACT [FMA:35252] synonym: "metacarpophalangeal joint of digit 2" EXACT [] synonym: "metacarpo-phalangeal joint of digit 2 of fore-paw" NARROW [EMAPA:25060] xref: FMA:35252 ! metacarpophalangeal joint of index finger xref: EMAPA:25060 ! metacarpo-phalangeal joint of digit 2 of fore-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004328 ! proximal phalanx of manual digit 2 relationship: part_of UBERON:0003622 {source="FMA"} ! manual digit 2 xref: SCTID:361845000 ! Entire metacarpophalangeal joint of index finger synonym: "metacarpophalangeal joint of index finger" NARROW SENSU [NCBITaxon:9606, FMA:35252] def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 2." [OBOL:automatic] [Term] id: UBERON:0007741 name: metacarpophalangeal joint of manual digit 3 synonym: "metacarpophalangeal joint of third digit of hand" EXACT [FMA:35255] synonym: "metacarpophalangeal joint of third finger" EXACT [FMA:35255] synonym: "carpometacarpophalangeal joint of third digit" NARROW SENSU [NCBITaxon:8782] synonym: "metacarpophalangeal joint of digit 3" EXACT [] synonym: "metacarpo-phalangeal joint of digit 3 of fore-paw" NARROW [EMAPA:25063] xref: FMA:35255 ! metacarpophalangeal joint of middle finger xref: EMAPA:25063 ! metacarpo-phalangeal joint of digit 3 of fore-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004329 ! proximal phalanx of manual digit 3 relationship: part_of UBERON:0003623 {source="FMA"} ! manual digit 3 xref: SCTID:361846004 ! Entire metacarpophalangeal joint of middle finger synonym: "metacarpophalangeal joint of middle finger" NARROW SENSU [NCBITaxon:9606, FMA:35255] def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 3." [OBOL:automatic] [Term] id: UBERON:0007744 name: metacarpophalangeal joint of manual digit 4 synonym: "metacarpophalangeal joint of fourth digit of hand" EXACT [FMA:35258] synonym: "metacarpophalangeal joint of fourth finger" EXACT [FMA:35258] synonym: "carpometacarpophalangeal joint of fourth digit" NARROW SENSU [NCBITaxon:8782] synonym: "metacarpo-phalangeal joint of digit 4 of fore-paw" NARROW [EMAPA:25066] synonym: "metacarpophalangeal joint of digit 4" EXACT [] xref: FMA:35258 ! metacarpophalangeal joint of ring finger xref: EMAPA:25066 ! metacarpo-phalangeal joint of digit 4 of fore-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004330 ! proximal phalanx of manual digit 4 relationship: part_of UBERON:0003624 {source="FMA"} ! manual digit 4 xref: SCTID:361847008 ! Entire metacarpophalangeal joint of ring finger synonym: "metacarpophalangeal joint of ring finger" NARROW SENSU [NCBITaxon:9606, FMA:35258] def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 4." [OBOL:automatic] [Term] id: UBERON:0007747 name: metacarpophalangeal joint of manual digit 5 synonym: "metacarpophalangeal joint of fifth digit of hand" EXACT [FMA:35261] synonym: "metacarpophalangeal joint of fifth finger" EXACT [FMA:35261] synonym: "metacarpo-phalangeal joint of digit 5 of fore-paw" NARROW [EMAPA:25069] synonym: "metacarpophalangeal joint of digit 5" EXACT [] xref: FMA:35261 ! metacarpophalangeal joint of little finger xref: EMAPA:25069 ! metacarpo-phalangeal joint of digit 5 of fore-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004331 ! proximal phalanx of manual digit 5 relationship: part_of UBERON:0003625 {source="FMA"} ! manual digit 5 xref: SCTID:361848003 ! Entire metacarpophalangeal joint of little finger synonym: "metacarpophalangeal joint of little finger" NARROW SENSU [NCBITaxon:9606, FMA:35261] def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 5." [OBOL:automatic] [Term] id: UBERON:0003696 name: metatarsophalangeal joint def: "The metatarsophalangeal articulations are the joints between the metatarsal bones of the foot and the proximal bones of the toes . They are condyloid joints meaning an elliptical or rounded surface (of the metatarsal bones) come close to the shallow cavities (of the proximal phalanges). The ligaments are the plantar and two collateral." [Wikipedia:Metatarsophalangeal_articulations] comment: Editor notes: we follow FMA in making these joints part of digits synonym: "metatarsophalangeal articulation" RELATED [Wikipedia:Metatarsophalangeal_articulations] synonym: "metatarsalphalangeal joint" RELATED [Wikipedia:Metatarsophalangeal_articulations] synonym: "metatarsophalangeal" RELATED [Wikipedia:Metatarsophalangeal_articulations] synonym: "metatarsal joint" RELATED [FMA:35222] xref: FMA:35222 ! Metatarsophalangeal joint xref: GAID:258 ! metatarsophalangeal joint xref: ncithesaurus:Metatarsophalangeal_Joint ! Metatarsophalangeal Joint xref: OpenCyc:Mx4rwCtS0pwpEbGdrcN5Y29ycA ! metatarsophalangeal joint xref: MESH:A02.835.583.378.531 ! metatarsophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0003867 ! distal phalanx of pes relationship: part_of UBERON:0001466 ! pedal digit xref: galen:MetatarsoPhalangealJoint xref: SCTID:239747005 ! Entire metatarsal joint xref: SCTID:302535003 ! Entire metatarsophalangeal joint synonym: "articulationes metatarsophalangeae" RELATED LATIN [Wikipedia:Metatarsophalangeal_articulations] xref: http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray268.png xref: UMLS:C0025589 [Term] id: UBERON:0007750 name: metatarsophalangeal joint of pedal digit 1 comment: note the name of the structure in EMAPA is incorrect synonym: "metatarsophalangeal joint of first digit of foot" EXACT [FMA:35228] synonym: "metatarsophalangeal joint of great toe" EXACT [FMA:35228] synonym: "first metatarsophalangeal joint" EXACT [] xref: FMA:35228 ! metatarsophalangeal joint of big toe xref: EMAPA:26436 ! metacarpo-phalangeal joint of digit 1 of hind-paw xref: SCTID:182223003 ! Entire first metatarsophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004315 ! distal phalanx of pedal digit 1 relationship: part_of UBERON:0003631 {source="FMA"} ! pedal digit 1 synonym: "metatarsophalangeal joint of big toe" NARROW SENSU [NCBITaxon:9606, FMA:35228] def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 1." [OBOL:automatic] [Term] id: UBERON:0007753 name: metatarsophalangeal joint of pedal digit 2 comment: note the name of the structure in EMAPA is incorrect synonym: "metatarsophalangeal joint of second digit of foot" EXACT [FMA:35231] xref: FMA:35231 ! metatarsophalangeal joint of second toe xref: EMAPA:26442 ! metacarpo-phalangeal joint of digit 2 of hind-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: part_of UBERON:0003632 {source="FMA"} ! pedal digit 2 xref: SCTID:361869001 ! Entire metatarsophalangeal joint of second toe synonym: "metatarsophalangeal joint of second toe" NARROW SENSU [NCBITaxon:9606, FMA:35231] def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 2." [OBOL:automatic] [Term] id: UBERON:0007756 name: metatarsophalangeal joint of pedal digit 3 comment: note the name of the structure in EMAPA is incorrect synonym: "metatarsophalangeal joint of third digit of foot" EXACT [FMA:35234] xref: FMA:35234 ! metatarsophalangeal joint of third toe xref: EMAPA:26460 ! metacarpo-phalangeal joint of digit 3 of hind-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: part_of UBERON:0003633 {source="FMA"} ! pedal digit 3 xref: SCTID:361870000 ! Entire metatarsophalangeal joint of third toe synonym: "metatarsophalangeal joint of third toe" NARROW SENSU [NCBITaxon:9606, FMA:35234] def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 3." [OBOL:automatic] [Term] id: UBERON:0007759 name: metatarsophalangeal joint of pedal digit 4 comment: note the name of the structure in EMAPA is incorrect synonym: "metatarsophalangeal joint of fourth digit of foot" EXACT [FMA:35237] xref: FMA:35237 ! metatarsophalangeal joint of fourth toe xref: EMAPA:26472 ! metacarpo-phalangeal joint of digit 4 of hind-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: part_of UBERON:0003634 {source="FMA"} ! pedal digit 4 xref: SCTID:361871001 ! Entire metatarsophalangeal joint of fourth toe synonym: "metatarsophalangeal joint of fourth toe" NARROW SENSU [NCBITaxon:9606, FMA:35237] def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 4." [OBOL:automatic] [Term] id: UBERON:0007762 name: metatarsophalangeal joint of pedal digit 5 comment: note the name of the structure in EMAPA is incorrect synonym: "metatarsophalangeal joint of fifth digit of foot" EXACT [FMA:35240] synonym: "metatarsophalangeal joint of fifth toe" EXACT [FMA:35240] xref: FMA:35240 ! metatarsophalangeal joint of little toe xref: EMAPA:26484 ! metacarpo-phalangeal joint of digit 5 of hind-paw intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004319 ! distal phalanx of pedal digit 5 relationship: part_of UBERON:0003635 {source="FMA"} ! pedal digit 5 xref: SCTID:361872008 ! Entire metatarsophalangeal joint of fifth toe synonym: "metatarsophalangeal joint of little toe" NARROW SENSU [NCBITaxon:9606, FMA:35240] def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 5." [OBOL:automatic] [Term] id: UBERON:0003697 name: abdominal wall def: "The abdominal wall represents the boundaries of the abdominal cavity. The abdominal wall is split into the posterior (back), lateral (sides) and anterior (front) walls. There is a common set of layers covering and forming all the walls: the deepest being the extraperitoneal fat, the parietal peritoneum, and a layer of fascia which has different names over where it covers (eg transversalis, psoas fascia). Superficial to these, but not present in the posterior wall are the three layers of muscle, the transversus abdominis (transverse abdominal muscle), the internal (obliquus internus) and the external oblique (obliquus externus)." [Wikipedia:Abdominal_wall] synonym: "layers of the abdominal wall" RELATED [Wikipedia:Abdominal_wall] synonym: "paries abdominalis" EXACT [Wikipedia:Abdominal_wall] synonym: "wall of abdomen" EXACT [FMA:259054] xref: FMA:10429 ! Wall of abdomen proper xref: FMA:259054 ! wall of abdomen xref: GAID:26 ! abdominal wall xref: MESH:A01.047.050 ! abdominal wall intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0000916 ! abdomen xref: ncithesaurus:Abdominal_Wall ! Abdominal Wall xref: SCTID:181613000 ! Entire abdominal wall synonym: "paries abdominalis" RELATED LATIN [Wikipedia:Abdominal_wall] xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg synonym: "wall of abdomen proper" EXACT [FMA:10429] xref: UMLS:C0836916 [Term] id: UBERON:0003699 name: pubic symphysis def: "the firm fibrocartilaginous joint in the median plane between the two opposing surfaces of the pubic bones, which are united by an interpubic disc of fibrocartilage as well as the superior and arcuate pubic ligaments." [MP:0009575, Wikipedia:Pubic_symphysis] comment: In birds, the pubic symphysis is present only in the ostrich, and the two hip bones are usually widely separated, making it easier to lay large eggs - Romer, Alfred Sherwood; Parsons, Thomas S. (1977). The Vertebrate Body. Philadelphia, PA: Holt-Saunders International. pp. 188–192. ISBN 0-03-910284-X. synonym: "interpubic articulation" RELATED [Wikipedia:Pubic_symphysis] synonym: "symphisis pubis" RELATED [Wikipedia:Pubic_symphysis] synonym: "symphysis pubis" RELATED [Wikipedia:Pubic_symphysis] synonym: "symphysis pubis" EXACT [FMA:16950] synonym: "symphisis pubis" RELATED [Wikipedia:Pubic_symphysis] xref: FMA:16950 ! Pubic symphysis xref: GAID:267 ! pubic symphysis xref: OpenCyc:Mx4rwGw9npwpEbGdrcN5Y29ycA ! pubic symphysis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/51/Gray321.png/200px-Gray321.png xref: MESH:A02.835.583.656 ! pubic symphysis is_a: UBERON:0002216 {source="FMA"} ! symphysis relationship: part_of UBERON:0002355 {source="FMA"} ! pelvis relationship: connects UBERON:0011091 ! skeleton of left pelvic girdle relationship: connects UBERON:0011090 ! skeleton of right pelvic girdle xref: AAO:0000769 ! pelvic girdle symphisis xref: SCTID:182200001 ! Entire symphysis pubis subset: organ_slim xref: ncithesaurus:Pubic_Symphisis ! pubic symphysis synonym: "symphysis pubica, symphysis pubis" RELATED LATIN [Wikipedia:Pubic_symphysis] xref: http://upload.wikimedia.org/wikipedia/commons/5/51/Gray321.png property_value: external_definition "Medial attachment of the two halves of the pelvic girdle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000769", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0034015 [Term] id: UBERON:0003700 name: temporomandibular joint def: "A joint of the jaw that connects the mandible to a temporal bone. There are two TMJs, one on either side, working in unison. The unique feature of the TMJs is the articular disc. The disc is composed of fibrocartilagenous tissue (like the firm and flexible elastic cartilage of the ear) which is positioned between the two bones that form the joint. The TMJs are one of the only synovial joints in the human body with an articular disc, another being the sternoclavicular joint. The disc divides each joint into two. The lower joint compartment formed by the mandible and the articular disc is involved in rotational movement -- this is the initial movement of the jaw when the mouth opens. The upper joint compartment formed by the articular disk and the temporal bone is involved in translational movement -- this is the secondary gliding motion of the jaw as it is opened widely. The part of the mandible which mates to the under-surface of the disc is the condyle and the part of the temporal bone which mates to the upper surface of the disk is the glenoid (or mandibular) fossa[WP]." [Wikipedia:Temporomandibular_joint] synonym: "tempero-mandibular joint" RELATED [Wikipedia:Temporomandibular_joint] synonym: "temporalmandibular joint" RELATED [Wikipedia:Temporomandibular_joint] synonym: "temporomandibular" RELATED [Wikipedia:Temporomandibular_joint] synonym: "temporomandibular articulation" RELATED [Wikipedia:Temporomandibular_joint] synonym: "temporomandibular joint" RELATED [Wikipedia:Temporomandibular_joint] synonym: "temperomandibular joint" EXACT [HP:0010754] synonym: "TMJ" EXACT [Wikipedia:Temporomandibular_joint, BTO:0003674] synonym: "dentary-squamosal joint" RELATED [http://palaeos.com/vertebrates/glossary/glossaryT.html] synonym: "squamosal-dentary joint" RELATED [http://palaeos.com/vertebrates/glossary/glossaryT.html] xref: FMA:54832 ! Temporomandibular joint xref: GAID:272 ! temporomandibular joint xref: MA:0002899 ! temporomandibular joint xref: BTO:0003674 ! temporomandibular joint xref: EMAPA:19196 ! temporo-mandibular joint xref: MESH:A02.835.583.861 ! temporomandibular joint is_a: UBERON:0011171 ! jaw joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001695 ! squamous part of temporal bone intersection_of: connects UBERON:0004742 ! dentary relationship: part_of UBERON:0000165 ! mouth relationship: develops_from UBERON:0011130 ! temporomandibular joint primordium xref: SCTID:181814009 ! Entire temporomandibular joint xref: ncithesaurus:Jaw_Joint ! jaw joint synonym: "articulatio temporomandibularis" RELATED LATIN [Wikipedia:Temporomandibular_joint] xref: http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray309.png relationship: in_lateral_side_of UBERON:0000165 {source="FMA-abduced-lr"} ! mouth xref: UMLS:C0039493 [Term] id: UBERON:0011130 ! temporomandibular joint primordium name: temporomandibular joint primordium is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0001694 {source="EMAPA"} ! petrous part of temporal bone synonym: "temporo-mandibular joint primordium" EXACT [EMAPA:18714] xref: EMAPA:18714 ! temporo-mandibular joint primordium [Term] id: UBERON:0011318 name: capsule of temporomandibular joint def: "The articular capsule (capsular ligament) is a thin, loose envelope, attached above to the circumference of the mandibular fossa and the articular tubercle immediately in front; below, to the neck of the condyle of the mandible." [Wikipedia:Capsule_of_temporomandibular_joint] synonym: "capsula articularis articulationis temporomandibularis" EXACT LATIN [Wikipedia:Capsule_of_the_temporomandibular_joint] intersection_of: UBERON:0001484 ! articular capsule intersection_of: part_of UBERON:0003700 ! temporomandibular joint xref: FMA:57050 ! articular capsule of temporomandibular joint xref: SCTID:303404000 ! Entire capsule of temporomandibular joint synonym: "articular capsule of temporomandibular joint" EXACT [FMA:57050] [Term] id: UBERON:0011319 name: disk of temporomandibular joint def: "The fibrocartilaginous plate that separates the joint into upper and lower cavities." [BTO:0003675, Wikipedia:Articular_disk_of_the_temporomandibular_joint] synonym: "articular disc of temporomandibular joint" EXACT [FMA:57059] synonym: "discus articularis (articulatio temporomandibularis)" EXACT [FMA:57059] synonym: "discus articularis articulationis temporomandibularis" EXACT LATIN [FMA:TA] synonym: "articular disc of temporomandibular joint" RELATED [BTO:0003675] synonym: "discus articularis temporomandibularis" RELATED [BTO:0003675] synonym: "mandibular disk" RELATED [BTO:0003675] synonym: "discus articularis articulationis temporomandibularis" EXACT LATIN [Wikipedia:Articular_disk_of_the_temporomandibular_joint] synonym: "temporomandibular joint disk" RELATED [Wikipedia:Articular_disk_of_the_temporomandibular_joint] synonym: "temporomandibular articular disk" RELATED [GAID:273] synonym: "temporomandibular articular disk" EXACT [BTO:0003675] is_a: UBERON:0007844 {source="FMA"} ! cartilage element relationship: part_of UBERON:0003700 {source="BTO"} ! temporomandibular joint xref: BTO:0003675 ! temporomandibular articular disk xref: MESH:A02.835.583.861.900 xref: FMA:57059 ! articular disk of temporomandibular joint xref: SCTID:282433007 ! Entire articular disc of temporomandibular joint synonym: "articular disk of temporomandibular joint" EXACT [FMA:57059] [Term] id: UBERON:0011320 name: ligament of temporomandibular joint def: "." [Wikipedia:Temporomandibular_joint#Ligaments] synonym: "temporomandibular joint ligament" EXACT [FMA:57070] intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: part_of UBERON:0003700 ! temporomandibular joint xref: FMA:57070 ! ligament of temporomandibular joint xref: SCTID:127861009 ! Ligament of temporomandibular joint [Term] id: UBERON:0011165 name: crico-esophageal tendon def: "Longitudinal fibers of the esophagus that attaches to the posterior aspect of the cricoid cartilage of the larynx" [http://www.medilexicon.com/medicaldictionary.php?t=90131] is_a: UBERON:0008845 {source="FMA"} ! nonskeletal ligament relationship: attaches_to UBERON:0002375 ! cricoid cartilage synonym: "cricoesophageal tendon" EXACT [] synonym: "crico-oesophageal tendon" EXACT [] synonym: "tendo cricoesophageus" EXACT [http://www.medilexicon.com/] synonym: "Gillette suspensory ligament" RELATED [http://www.medilexicon.com/] synonym: "suspensory ligament of esophagus" RELATED [http://www.medilexicon.com/] xref: FMA:76887 ! crico-oesophageal tendon xref: SCTID:322841005 ! Entire cricoesophageal tendon xref: ncithesaurus:Cricoesophageal_Tendon ! cricoesophageal tendon xref: UMLS:C0227182 [Term] id: UBERON:0003701 name: calcaneal tendon def: "The Achilles tendon is a tendon of the posterior leg. It serves to attach the plantaris, gastrocnemius (calf) and soleus muscles to the calcaneus (heel) bone." [Wikipedia:Achilles_tendon] comment: AO notes: in FMA this is a ligament, and part of the muscle synonym: "Achille's tendon" EXACT [] synonym: "Achilles' tendon" EXACT [] synonym: "calcaneal tendon" EXACT [FMA:51061] synonym: "tendo calcaneus" EXACT LATIN [MA:0002993] synonym: "tendo Achillis" EXACT LATIN [Wikipedia:Achilles_tendon] synonym: "Achilles tendon" EXACT [MA:0002993] xref: FMA:51061 ! Calcaneal tendon xref: GAID:277 ! achilles tendon xref: ncithesaurus:Achilles_Tendon ! Achilles Tendon xref: OpenCyc:Mx4rvVjNX5wpEbGdrcN5Y29ycA ! achilles tendon xref: MA:0002993 ! tendo calcaneus xref: MESH:A02.880.176 ! achilles tendon is_a: UBERON:0000043 {source="MA"} ! tendon intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0001450 ! calcaneus relationship: connects UBERON:0001383 ! muscle of leg relationship: part_of UBERON:0001665 {source="FMA"} ! triceps surae xref: SCTID:181705009 ! Entire achilles tendon xref: http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg xref: UMLS:C0001074 [Term] id: UBERON:0003705 name: meckel's diverticulum def: "a small bulge in the small intestine present at birth. It is a vestigial remnant of the omphalomesenteric duct" [Wikipedia:Meckel\'s_diverticulum] comment: AO notes: finding in ncit; GALT in chickens synonym: "diverticulum of meckel" EXACT [FMA:14967] synonym: "meckel diverticulum" RELATED [GAID:317] synonym: "meckel's diverticulum" EXACT [FMA:14967] synonym: "meckels diverticulum" RELATED [GAID:317] synonym: "ileal diverticulum" EXACT [FMA:14967] xref: FMA:14967 ! Ileal diverticulum xref: GAID:317 ! meckel's diverticulum xref: MESH:A03.492.411.620.484.612 ! meckel's diverticulum is_a: UBERON:0006590 ! vestigial embryonic structure relationship: part_of UBERON:0002116 ! ileum relationship: develops_from UBERON:0007105 {source="Wikipedia"} ! vitelline duct xref: ncithesaurus:Meckel_Diverticulum ! Meckel Diverticulum xref: galen:MeckelsDiverticulum [Term] id: UBERON:0007105 name: vitelline duct def: "In the human embryo, the vitelline duct, also known as the omphalomesenteric duct, is a long narrow tube that joins the yolk-sac to the midgut lumen of the developing fetus. It appears at the end of the fourth week, when the yolk-sac presents the appearance of a small pear-shaped vesicle (the umbilical vesicle). The vesicle can be seen in the afterbirth as a small, somewhat oval-shaped body whose diameter varies from 1 mm to 5 mm. It is situated between the amnion and the chorion and may lie on or at a varying distance from the placenta. Generally, the duct fully obliterates (narrows and disappears) during the seventh week, but a failure of the duct to close is termed a vitelline fistula. This results in discharge of meconium from the umbilicus. About two per cent of fetuses exhibit a type of vitelline fistula characterized by persistence of the proximal part of the vitelline duct as a diverticulum protruding from the small intestine, Meckel's diverticulum, which is situated about two feet above the ileocecal junction, and may be attached by a fibrous cord to the abdominal wall at the umbilicus. Sometimes a narrowing of the lumen of the ileum is seen opposite the site of attachment of the duct." [Wikipedia:Vitelline_duct] synonym: "ductus vitellinus" RELATED [] synonym: "embryonic yolk stalk" RELATED [Wikipedia:Vitelline_duct] synonym: "omphalomesenteric duct" RELATED [Wikipedia:Vitelline_duct] synonym: "yolk duct" RELATED [Wikipedia:Vitelline_duct] synonym: "yolk-stalk" RELATED [Wikipedia:Vitelline_duct] synonym: "omphalomesenteric duct" RELATED [MESH:A16.254.891] xref: Wikipedia:Vitelline_duct ! vitelline duct xref: MESH:A16.254.891 ! vitelline duct xref: GAID:1314 ! vitelline duct xref: EMAPA:26139 ! vitelline duct is_a: UBERON:0000058 ! duct relationship: develops_from UBERON:0001045 ! midgut xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray30.png xref: SCTID:280701007 ! Entire yolk stalk [Term] id: UBERON:0003707 name: sinus of Valsalva def: "one of the anatomic dilations of the ascending aorta, which occurs just above the aortic valve." [Wikipedia:Aortic_sinus] synonym: "aortic sinus" RELATED [GAID:472] synonym: "Valsalva sinus" RELATED [GAID:472] synonym: "sinus aortae" RELATED [Wikipedia:Aortic_sinus] synonym: "sinus aorta" RELATED [Wikipedia:Aortic_sinus] synonym: "sinus of Morgagni" RELATED [Wikipedia:Aortic_sinus] synonym: "sinus of Otto" RELATED [Wikipedia:Aortic_sinus] synonym: "Petit's sinus" RELATED [Wikipedia:Aortic_sinus] xref: FMA:3745 ! Aortic sinus xref: GAID:472 ! sinus of valsalva xref: EMAPA:18625 ! aortic sinus xref: MESH:A07.231.114.056.847 ! sinus of valsalva xref: ncithesaurus:Sinus_of_Valsava ! sinus of valsava is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0010172 {source="MP"} ! bulb of aorta synonym: "sinus aortae" RELATED LATIN [Wikipedia:Aortic_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/5/54/Gray497.png xref: SCTID:277732004 ! Entire sinus of Valsalva xref: UMLS:C0503361 [Term] id: UBERON:0003708 name: carotid sinus def: "In human anatomy, the carotid sinus is a localized dilation of the internal carotid artery at its origin, the common carotid artery bifurcation. A synonym for the carotid sinus is the carotid bulb. [WP,unvetted]." [Wikipedia:Carotid_sinus] xref: FMA:50094 ! Carotid sinus xref: GAID:482 ! carotid sinus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9c/Gray513.png/200px-Gray513.png xref: EMAPA:19320 ! carotid sinus xref: MESH:A07.231.114.186.456 ! carotid sinus is_a: UBERON:0001530 ! common carotid artery xref: SCTID:281137000 ! Entire carotid sinus synonym: "sinus caroticus" RELATED LATIN [Wikipedia:Carotid_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/9/9c/Gray513.png [Term] id: UBERON:0003709 name: circle of Willis def: "a circle of arteries that supply blood to the brain. The Circle of Willis comprises the following arteries: Anterior cerebral artery (left and right); Anterior communicating artery; Internal carotid artery (left and right); Posterior cerebral artery (left and right); Posterior communicating artery (left and right).The basilar artery and middle cerebral arteries, supplying the brain, are also considered part of the circle" [Wikipedia:Circle_of_Willis] comment: In zebrafish, the circle of vessels comprised of the basal communicating artery (BCA) and posterior communicating segments (PCS) superficially resemble but are not homologous to the human circle of Willis[http://zfish.nichd.nih.gov/zfatlas/Intro%20Page/comparative.html]. Editor note: synonym: "cerebral arterial circle" RELATED [GAID:486] synonym: "arterial circle of Willis" EXACT [] synonym: "arterial circle" BROAD [Wikipedia:Circle_of_Willis] synonym: "Willis circle" RELATED [GAID:486] xref: FMA:50454 ! Cerebral arterial circle xref: GAID:486 ! circle of willis xref: EHDAA:9758 ! circle of Willis xref: OpenCyc:Mx4rwSrCwJwpEbGdrcN5Y29ycA ! circle of Willis xref: EHDAA2:0000252 ! circle of Willis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Circle_of_Willis_en.svg/200px-Circle_of_Willis_en.svg.png xref: MESH:A07.231.114.228.351 ! circle of willis is_a: UBERON:0004573 ! systemic artery relationship: overlaps UBERON:0007143 {source="FMA-modified"} ! right internal carotid artery relationship: overlaps UBERON:0007142 {source="FMA-modified"} ! left internal carotid artery xref: SCTID:362047009 ! Entire circle of Willis synonym: "circulus arteriosus cerebri" RELATED LATIN [Wikipedia:Circle_of_Willis] xref: http://upload.wikimedia.org/wikipedia/commons/2/2e/Circle_of_Willis_en.svg [Term] id: UBERON:0003710 name: vasa vasorum def: "Nutrient blood vessels which supply the walls of large arteries or veins." [MESH:A07.231.836, http://en.wikipedia.org/wiki/Vasa_vasorum] comment: Taxon notes: The aorta of swine contains a vaso vasorum like humans - http://www.nal.usda.gov/awic/pubs/swine/swine.htm#art xref: FMA:77433 ! Vasa vasorum xref: GAID:526 ! vasa vasorum xref: ncithesaurus:Vasa_Vasorum ! Vasa Vasorum xref: MESH:A07.231.836 ! vasa vasorum is_a: UBERON:0001981 ! blood vessel xref: SCTID:7524009 ! Entire vasa vasorum xref: UMLS:C0042367 [Term] id: UBERON:0003712 name: cavernous sinus def: "The cavernous sinus (or lateral sellar compartment), within the human head, is a large collection of thin-walled veins creating a cavity bordered by the temporal bone of the skull and the sphenoid bone, lateral to the sella turcica." [Wikipedia:Cavernous_sinus] synonym: "cavernous" RELATED [Wikipedia:Cavernous_sinus] synonym: "cavernous sinus syndrome" RELATED [Wikipedia:Cavernous_sinus] synonym: "cavernous sinuses" RELATED [Wikipedia:Cavernous_sinus] synonym: "cavernus sinus vein" RELATED [Wikipedia:Cavernous_sinus] synonym: "parasellar syndrome" RELATED [Wikipedia:Cavernous_sinus] synonym: "sinus cavernosus" RELATED [Wikipedia:Cavernous_sinus] xref: FMA:50772 ! Cavernous sinus xref: GAID:532 ! cavernous sinus xref: ncithesaurus:Cavernous_Sinus ! Cavernous Sinus xref: OpenCyc:Mx4rwKAVGJwpEbGdrcN5Y29ycA ! cavernous sinus xref: EMAPA:19059 ! cavernous xref: MESH:A07.231.908.224.334 ! cavernous sinus is_a: UBERON:0005486 ! venous dural sinus xref: SCTID:244402005 ! Entire cavernous sinus property_value: external_definition "An irregularly shaped venous space in the dura mater at either side of the sphenoid bone[MESH:A07.231.908.224.334]." xsd:string {source="MESH:A07.231.908.224.334"} xref: UMLS:C0007473 [Term] id: UBERON:0003713 name: splenic vein def: "In anatomy, the splenic vein (in the past called the lienal vein) is the blood vessel that drains blood from the spleen. It joins with the superior mesenteric vein, to form the hepatic portal vein and follows a course superior to the pancreas, alongside of the similarly named artery, the splenic artery. It collects branches from the stomach and pancreas and most notably from the large intestine, which is drained by the inferior mesenteric vein and joins with splenic vein shortly before it forms the portal vein. [WP,unvetted]." [Wikipedia:Splenic_vein] synonym: "lienal vein" RELATED [MA:0002164, Wikipedia:Splenic_vein] synonym: "vena lienalis" RELATED LATIN [Wikipedia:Splenic_vein] xref: FMA:14331 ! Splenic vein xref: GAID:541 ! splenic vein xref: ncithesaurus:Splenic_Vein ! Splenic Vein xref: galen:SplenicVein ! splenic vein xref: OpenCyc:Mx4rwCt0eZwpEbGdrcN5Y29ycA ! splenic vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Gray1189.png/200px-Gray1189.png xref: MESH:A07.231.908.670.730 ! splenic vein xref: MA:0002164 ! lienal vein is_a: UBERON:0001638 ! vein xref: SCTID:278029005 ! Entire splenic vein xref: http://upload.wikimedia.org/wikipedia/commons/e/e4/Bilebladder.png xref: UMLS:C0038001 [Term] id: UBERON:0003714 ! neural tissue name: neural tissue def: "Portion of tissue which consists of neurons, neuroglia and vasculature. Examples: Neural tissue of brain, neural tissue of peripheral ganglion, neural tissue of nerve[FMA]." [FMA:9642] comment: FMA definition includes vasculature synonym: "nerve tissue" EXACT [FMA:9642] synonym: "nervous tissue" EXACT [FMA:9642] synonym: "portion of neural tissue" EXACT [FMA:9642] xref: FMA:9642 ! Portion of neural tissue xref: GAID:609 ! nerve tissue xref: ncithesaurus:Nervous_Tissue ! Nerve Tissue xref: OpenCyc:Mx4rVmfYCsQ_QdeM_bFAeS8NRQ ! nerve tissue xref: EHDAA2:0003123 ! neural tissue xref: AEO:0000123 ! neural tissue xref: AAO:0000325 ! nervous tissue xref: MESH:A08.561 ! nerve tissue intersection_of: UBERON:0000479 ! portion of tissue intersection_of: has_part CL:0000125 ! glial cell intersection_of: has_part CL:0000540 ! neuron relationship: part_of UBERON:0001016 ! nervous system xref: SCTID:91728009 ! Structure of nervous tissue property_value: external_definition "One of the four types of tissue in traditional classifications. Cells forming the brain, spinal cord and peripheral nervous system.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000325", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0027757 [Term] id: UBERON:0003715 name: splanchnic nerve def: "the major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia." [MP:0008318] xref: FMA:5883 ! Splanchnic nerve xref: GAID:800 ! splanchnic nerve xref: MESH:A08.800.050.050.800 ! splanchnic nerve is_a: UBERON:0001021 ! nerve relationship: part_of UBERON:0000013 ! sympathetic nervous system xref: SCTID:264198001 ! Splanchnic nerve [Term] id: UBERON:0003716 name: recurrent laryngeal nerve def: "A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch." [Wikipedia:Recurrent_laryngeal_nerve] synonym: "inferior laryngeal nerve" RELATED [GAID:804] synonym: "recurrent nerve" BROAD [Wikipedia:Recurrent_laryngeal_nerve] synonym: "nervus laryngeus recurrens" EXACT LATIN [Wikipedia:Recurrent_laryngeal_nerve] synonym: "recurrent laryngeal nerve from vagus nerve" EXACT [] synonym: "vagus X nerve recurrent laryngeal branch" EXACT [VHOG:0001347] xref: FMA:6246 ! Recurrent laryngeal nerve xref: GAID:804 ! recurrent laryngeal nerve xref: MESH:A08.800.050.050.925.450.700 ! recurrent laryngeal nerve is_a: UBERON:0002003 ! peripheral nerve relationship: branch_of UBERON:0001759 ! vagus nerve xref: SCTID:24227007 ! Structure of recurrent laryngeal nerve xref: http://en.wikipedia.org/wiki/File:Gray793.png xref: VHOG:0001347 ! vagus X nerve recurrent laryngeal branch [Term] id: UBERON:0011766 name: vagus X nerve left recurrent laryngeal branch is_a: UBERON:0003716 {source="FMA"} ! recurrent laryngeal nerve xref: MA:0001107 ! vagus X nerve left recurrent laryngeal branch xref: SCTID:280300006 ! Left recurrent laryngeal nerve xref: EMAPA:25350 ! left recurrent laryngeal branch xref: FMA:14469 ! left recurrent laryngeal nerve synonym: "left recurrent laryngeal branch" EXACT [EMAPA:25350] synonym: "left recurrent laryngeal nerve" EXACT [FMA:14469] [Term] id: UBERON:0011767 name: vagus X nerve right recurrent laryngeal branch is_a: UBERON:0003716 {source="FMA"} ! recurrent laryngeal nerve xref: MA:0001108 ! vagus X nerve right recurrent laryngeal branch xref: SCTID:280299003 ! Right recurrent laryngeal nerve xref: EMAPA:17275 ! right recurrent laryngeal branch xref: FMA:14468 ! right recurrent laryngeal nerve synonym: "right recurrent laryngeal branch" EXACT [EMAPA:17275] synonym: "right recurrent laryngeal nerve" EXACT [FMA:14468] [Term] id: UBERON:0011326 name: superior laryngeal nerve def: "The superior laryngeal nerve is a branch of the vagus nerve. It arises from the middle of the ganglion nodosum and in its course receives a branch from the superior cervical ganglion of the sympathetic. It descends, by the side of the pharynx, behind the internal carotid artery, and divides into two branches: external laryngeal nerve internal laryngeal nerve A superior laryngeal nerve palsy changes the pitch of the voice and causes an inability to make explosive sounds. If no recovery is evident three months after the palsy initially presents, the damage is most likely to be permanent. A bilateral palsy presents as a tiring and hoarse voice." [Wikipedia:Superior_laryngeal_nerve] synonym: "nervus laryngealis superior" EXACT [FMA:6239] synonym: "superior laryngeal branch of inferior vagal ganglion" EXACT [FMA:6239] synonym: "superior laryngeal branch of vagus" EXACT [FMA:6239] synonym: "nervus laryngeus superior" EXACT LATIN [Wikipedia:Superior_laryngeal_nerve] is_a: UBERON:0002003 ! peripheral nerve relationship: branch_of UBERON:0001759 {source="FMA"} ! vagus nerve xref: FMA:6239 ! superior laryngeal nerve xref: SCTID:279928006 ! Entire superior laryngeal nerve [Term] id: UBERON:0011321 ! masseteric nerve name: masseteric nerve def: "The masseteric nerve passes laterally, above the Pterygoideus externus, in front of the temporomandibular articulation, and behind the tendon of the Temporalis; it crosses the mandibular notch with the masseteric artery, to the deep surface of the Masseter, in which it ramifies nearly as far as its anterior border. It gives a filament to the temporomandibular joint." [Wikipedia:Masseteric_nerve] is_a: UBERON:0002003 ! peripheral nerve relationship: branch_of UBERON:0000375 {source="FMA"} ! mandibular nerve synonym: "nervus massetericus" EXACT LATIN [Wikipedia:Masseteric_nerve] xref: FMA:53103 ! masseteric nerve xref: SCTID:280254006 ! Entire masseteric nerve [Term] id: UBERON:0011327 name: deep temporal nerve def: "The deep temporal nerves, branches of the mandibular division of the trigeminal nerve, are two in number, anterior and posterior. They pass above the upper border of the pterygoideus externus and enter the deep surface of the temporalis." [Wikipedia:Deep_temporal_nerves] synonym: "deep temporal nerve" RELATED [Wikipedia:Deep_temporal_nerves] synonym: "nervi temporales profundi" EXACT PLURAL [FMA:TA] is_a: UBERON:0002003 ! peripheral nerve relationship: branch_of UBERON:0000375 {source="FMA"} ! mandibular nerve xref: FMA:53187 ! deep temporal nerve xref: SCTID:280255007 ! Entire deep temporal nerve [Term] id: UBERON:0003718 name: muscle spindle def: "the sensory organs in muscle that are involved in the stretch reflex." [MP:0004069] synonym: "muscle stretch receptor" RELATED [GAID:819] synonym: "neuromuscular spindle" RELATED [GAID:819] synonym: "neuromuscular spindle" EXACT [FMA:83607] xref: FMA:83607 ! Muscle spindle xref: GAID:819 ! muscle spindle xref: ncithesaurus:Muscle_Spindle ! Muscle Spindle xref: MESH:A08.800.550.700.500.500 ! muscle spindle is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001016 ! nervous system xref: SCTID:12945004 ! Muscle spindle xref: UMLS:C0027871 [Term] id: UBERON:0012453 name: nerve ending def: "Specialized terminations of peripheral neurons. Nerve endings include NEUROEFFECTOR JUNCTION(s) by which neurons activate target organs and sensory receptors (see RECEPTORS, SENSORY) which transduce information from the various sensory modalities and send it centrally in the nervous system. Presynaptic nerve endings are PRESYNAPTIC TERMINALS." [MESH:A08.800.550] comment: This class and subclasses may be ceded to GO synonym: "nerve ending" RELATED [MESH:A08.800.550] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0000010 ! peripheral nervous system relationship: part_of UBERON:0001027 ! sensory nerve xref: MESH:A08.800.550 ! nerve ending [Term] id: UBERON:0012451 name: sensory receptor def: "a sensory nerve ending that responds to a stimulus in the internal or external environment of an organism. In response to stimuli the sensory receptor initiates sensory transduction by creating graded potentials or action potentials in the same cell or in an adjacent one.." [Wikipedia:Sensory_receptor] synonym: "peripheral ending of sensory neuron" EXACT [FMA:84650] synonym: "sensory nerve ending" RELATED [MESH:A08.800.550.700] is_a: UBERON:0012453 {source="MESH"} ! nerve ending xref: FMA:84650 ! sensory receptor xref: SCTID:70402007 ! Peripheral sensory structure xref: ncithesaurus:Somatosensory_Receptor ! somatosensory receptor xref: MESH:A08.800.550.700 ! sensory receptor xref: UMLS:C0682664 [Term] id: UBERON:0012449 name: mechanoreceptor def: "a sensory receptor that responds to mechanical pressure or distortion. Normally there are four main types in glabrous skin: Pacinian corpuscles, Meissner's corpuscles, Merkel's discs, and Ruffini endings. There are also mechanoreceptors in hairy skin, and the hair cells in the cochlea are the most sensitive mechanoreceptors, transducing air pressure waves into nerve signals sent to the brain. In the periodontal ligament, there are some mechanoreceptors, which allow the jaw to relax when biting down on hard objects; the mesencephalic nucleus is responsible for this reflex." [Wikipedia:Mechanoreceptor] synonym: "contact receptor" RELATED [FMA:85595] is_a: UBERON:0012451 {source="MESH"} ! sensory receptor xref: FMA:85595 ! contact receptor xref: MESH:A08.800.550.700.500 ! mechanoreceptor [Term] id: UBERON:0003719 alt_id: UBERON:0003717 name: Pacinian corpuscle def: "any of the rapidly adapting mechanoreceptors found in subcutaneous tissue beneath both hairy and glabrous skin, and which normally contain an afferent nerve fiber surrounded by a capsule with multiple concentric layers." [MP:0000988, Wikipedia:Lamellar_corpuscle] comment: AO notes: FMA treats pacinia and G-M as distinct synonym: "corpusculum lamellosum" EXACT LATIN [Wikipedia:Lamellar_corpuscle] synonym: "lamellar corpuscle" EXACT [Wikipedia:Lamellar_corpuscle] synonym: "Pacinian corpuscle" EXACT [Wikipedia:Lamellar_corpuscle] synonym: "golgi mazzoni corpuscle" RELATED [GAID:817] synonym: "golgi-mazzoni corpuscle" EXACT [FMA:83609] synonym: "corpuscle of golgi-mazzoni" EXACT [FMA:83609] synonym: "golgi-mazzoni" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "golgi-mazzoni corpuscles" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "lamellated corpuscle" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "pacinian body" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "pacinian corpuscle" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "pacinian corpuscle end-organs" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "pacinian corpuscles" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "vater-pacini corpuscle" RELATED [Wikipedia:Pacinian_corpuscle] synonym: "vater-pacini corpuscles" RELATED [Wikipedia:Pacinian_corpuscle] xref: FMA:83604 ! Pacinian corpuscle xref: GAID:820 ! pacinian corpuscle xref: NIF_Subcellular:FMA_83604 ! Pacinian corpuscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/52/Gray935.png/200px-Gray935.png xref: MESH:A08.800.550.700.500.700 ! pacinian corpuscle xref: FMA:83609 ! Corpuscle of Golgi-Mazzoni xref: GAID:817 ! golgi-mazzoni corpuscle xref: MESH:A08.800.550.700.500.300 ! golgi-mazzoni corpuscle xref: SCTID:37419002 ! Golgi-Mazzoni corpuscle xref: http://en.wikipedia.org/wiki/File:Gray935.png is_a: UBERON:0012449 {source="Wikipedia"} ! mechanoreceptor relationship: part_of UBERON:0002067 {notes="may also be located in organs - check"} ! dermis [Term] id: UBERON:0012448 name: corpuscles of herbst def: "The Corpuscles of Herbst or Herbst corpuscles are a nerve-ending similar to the Pacinian corpuscle, in the mucous membrane of the tongue, in pits on the beak and in other parts of the bodies of birds. It differs from the Pacinian corpuscle in being smaller, in its capsules being more closely approximated, and in that the axis-cylinder in the central clear space is coated with a continuous row of nuclei. In many wading birds, a large number of Herbst corpuscles are found embedded in pits on the mandibles that are believed to enable birds to sense prey under wet sand or soil." [Wikipedia:Corpuscles_of_Herbst] synonym: "corpuscles of herbst" RELATED [Wikipedia:Corpuscles_of_Herbst] synonym: "herbst corpuscle" RELATED [Wikipedia:Corpuscles_of_Herbst] is_a: UBERON:0012449 {source="Wikipedia"} ! mechanoreceptor [Term] id: UBERON:0012450 name: Meisner's corpuscle def: "Meissner's corpuscles (or tactile corpuscles) are a type of mechanoreceptor. They are a type of nerve ending in the skin that is responsible for sensitivity to light touch. In particular, they have highest sensitivity (lowest threshold) when sensing vibrations lower than 50 Hertz. They are rapidly adaptive receptors." [Wikipedia:Meissner%27s_corpuscle] synonym: "meisner%27s corpuscle" RELATED [Wikipedia:Meissner%27s_corpuscle] synonym: "meissner corpuscle" RELATED [Wikipedia:Meissner%27s_corpuscle] synonym: "meissner corpuscle end-organ" RELATED [Wikipedia:Meissner%27s_corpuscle] synonym: "meissner%27s corpuscle" RELATED [Wikipedia:Meissner%27s_corpuscle] synonym: "meissner%27s corpuscles" RELATED [Wikipedia:Meissner%27s_corpuscle] synonym: "messier corpuscle" RELATED [Wikipedia:Meissner%27s_corpuscle] synonym: "messner%27s corpuscle" RELATED [Wikipedia:Meissner%27s_corpuscle] synonym: "tactile corpuscles of wagner and meissner" RELATED [Wikipedia:Meissner%27s_corpuscle] is_a: UBERON:0012449 {source="Wikipedia"} ! mechanoreceptor relationship: part_of UBERON:0002199 ! integument xref: FMA:83605 ! meisner's corpuscle xref: ncithesaurus:Meissner_Corpuscle ! meissner corpuscle xref: SCTID:41421000 ! Meissner's corpuscle xref: UMLS:C0205831 [Term] id: UBERON:0012456 name: Merkel nerve ending def: "mechanoreceptors found in the skin and mucosa of vertebrates that provide touch information to the brain. The information they provide are those regarding pressure and texture. Each ending consists of a Merkel cell in close apposition with an enlarged nerve terminal" [Wikipedia:Merkel_nerve_ending] comment: Location: In mammals, Merkel nerve endings have a wide distribution. Merkel nerve endings are found in the basal layer of glabrous and hairy skin, in hair follicles, and in oral and anal mucosa. In humans, Merkel cells (along with Meissner's corpuscles) occur in the superficial skin layers, and are found clustered beneath the ridges of the fingertips that make up fingerprints. In hairy skin, Merkel nerve endings are clustered into specialized epithelial structures called "touch domes" or "hair disks". (Some other types of mechanoreceptors, such as Pacinian corpuscles and Ruffini endings, are found primarily in subcutaneous tissue.) Merkel receptors are also located in the mammary glands. Wherever they are found, the epithelium is arranged to optimize the transfer of pressure to the ending.[WP] synonym: "Merkel's disk" EXACT [] synonym: "Merkel's disc" EXACT [FMA:83606] synonym: "Merkel's tactile disc" EXACT [] intersection_of: UBERON:0012449 ! mechanoreceptor intersection_of: part_of CL:0000242 ! Merkel cell relationship: part_of UBERON:0002199 ! integument xref: FMA:83606 ! Merkel's disc xref: SCTID:9317004 ! Merkel's tactile disc xref: NIF_Subcellular:FMA_83606 ! Merkels disc [Term] id: UBERON:0012457 name: Ruffini nerve ending def: "The Ruffini ending or Ruffini corpuscle is a class of slowly adapting mechanoreceptor which in humans is thought to exist only in the glabrous dermis and subcutaneous tissue[WP]." [Wikipedia:Bulbous_corpuscle] comment: AO notes: MP says subcutaneous tissue of digits; NCITA says hypodermis synonym: "corpusculum sensorium fusiforme" EXACT LATIN [Wikipedia:Ruffini_ending] synonym: "bulbous corpuscle" RELATED [Wikipedia:Ruffini_ending] synonym: "corpuscle of ruffini" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini corpuscle" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini corpuscle end-organ" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini corpuscles" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini endings" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini%27s corpuscles" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini%27s end organ" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini%27s ending" RELATED [Wikipedia:Ruffini_ending] synonym: "ruffini%27s organs" RELATED [Wikipedia:Ruffini_ending] synonym: "Ruffini's corpuscle" EXACT [MP:0000989] is_a: UBERON:0012449 {source="FMA"} ! mechanoreceptor relationship: part_of UBERON:0002199 ! integument xref: FMA:83602 ! end bulb of ruffini xref: FMA:84004 ! nerve ending within end bulb of ruffini xref: SCTID:53140000 ! Ruffini's corpuscle xref: ncithesaurus:Ruffinis_Corpuscle ! ruffini corpuscle xref: UMLS:C0035943 [Term] id: UBERON:0003720 name: anterior cranial fossa def: "The floor of the anterior fossa is formed by the orbital plates of the frontal, the cribriform plate of the ethmoid, and the small wings and front part of the body of the sphenoid; it is limited behind by the posterior borders of the small wings of the sphenoid and by the anterior margin of the chiasmatic groove. The lesser wings of the sphenoid separate the anterior and middle fossae." [Wikipedia:Anterior_cranial_fossa] xref: FMA:9682 ! Anterior cranial fossa xref: GAID:83 ! anterior cranial fossa xref: ncithesaurus:Anterior_Fossa ! Anterior Cranial Fossa xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/81/Gray193.png/200px-Gray193.png xref: MESH:A01.456.830.150 ! anterior cranial fossa synonym: "anterior fossa" BROAD [] is_a: UBERON:0004704 ! bone fossa relationship: part_of UBERON:0003128 ! cranium synonym: "fossa cranii anterior" RELATED LATIN [Wikipedia:Anterior_cranial_fossa] xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png xref: UMLS:C0230044 [Term] id: UBERON:0003721 name: lingual nerve xref: FMA:53218 ! Lingual nerve xref: GAID:835 ! lingual nerve xref: MESH:A08.800.800.120.760.500.450 ! lingual nerve is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0000375 ! mandibular nerve xref: SCTID:280260006 ! Entire lingual nerve [Term] id: UBERON:0003722 name: middle cranial fossa def: "The compartment containing the anterior extremities and half the inferior surface of the temporal lobes (TEMPORAL LOBE) of the cerebral hemispheres. Lying posterior and inferior to the anterior cranial fossa (CRANIAL FOSSA, ANTERIOR), it is formed by part of the TEMPORAL BONE and SPHENOID BONE. It is separated from the posterior cranial fossa (CRANIAL FOSSA, POSTERIOR) by crests formed by the superior borders of the petrous parts of the temporal bones[MESH]. The middle fossa, deeper than the anterior cranial fossa, is narrow medially and widens laterally to the sides of the skull. It is separated from the posterior fossa by the clivus and the petrous crest. It is bounded in front by the posterior margins of the lesser wings of the sphenoid bone, the anterior clinoid processes, and the ridge forming the anterior margin of the chiasmatic groove; behind, by the superior angles of the petrous portions of the temporal bones and the dorsum sellC&; laterally by the temporal squamC&, sphenoidal angles of the parietals, and greater wings of the sphenoid. It is traversed by the squamosal, sphenoparietal, sphenosquamosal, and sphenopetrosal sutures[WP]." [MESH:A01.456.830.165, Wikipedia:Middle_cranial_fossa] synonym: "middle fossa" BROAD [Wikipedia:Middle_cranial_fossa] xref: FMA:54369 ! Middle cranial fossa xref: GAID:84 ! middle cranial fossa xref: ncithesaurus:Middle_Fossa ! Middle Cranial Fossa xref: MESH:A01.456.830.165 ! middle cranial fossa is_a: UBERON:0004704 ! bone fossa relationship: part_of UBERON:0003128 ! cranium synonym: "fossa cranii media" RELATED LATIN [Wikipedia:Middle_cranial_fossa] xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png xref: UMLS:C0230045 [Term] id: UBERON:0008788 ! posterior cranial fossa name: posterior cranial fossa def: "The infratentorial compartment that contains the CEREBELLUM and BRAIN STEM. It is formed by the posterior third of the superior surface of the body of the sphenoid (SPHENOID BONE), by the occipital, the petrous, and mastoid portions of the TEMPORAL BONE, and the posterior inferior angle of the PARIETAL BONE." [MESH:A01.456.830.200, Wikipedia:Posterior_cranial_fossa] xref: FMA:54368 ! posterior cranial fossa xref: MESH:A01.456.830.200 xref: GAID:85 ! posterior cranial fossa xref: ncithesaurus:Posterior_Fossa ! posterior fossa synonym: "posterior fossa" BROAD [ncithesaurus:Posterior] is_a: UBERON:0004704 ! bone fossa relationship: part_of UBERON:0003128 ! cranium synonym: "fossa cranii posterior" RELATED LATIN [Wikipedia:Posterior_cranial_fossa] xref: http://upload.wikimedia.org/wikipedia/commons/c/c2/Posterior_fossa.png xref: UMLS:C0010265 [Term] id: UBERON:0008789 name: cranial fossa def: "any of the three large depressions in the posterior, middle, and anterior aspects of the floor of the cranial cavity" [http://mw1.merriam-webster.com/medical/cranial%20fossa] comment: editor note - todo - review the relationships for this and its subclasses; the relation should be bounded rather than part of, and contains should be used for the brain parts contained by the fossae intersection_of: UBERON:0004704 ! bone fossa intersection_of: part_of UBERON:0003128 ! cranium relationship: part_of UBERON:0004766 {is_inferred="true", source="reference_0000032"} ! cranial bone [Term] id: UBERON:0004704 ! bone fossa name: bone fossa def: "a depression or hollow in a bone[WP]." [Wikipedia:Fossa#Anatomy] comment: AO notes: General Anatomical term in FMA; not restricted to bone in ncit; surface feature in VSAO; note that entities named 'fossa' are cavities in FMA, hence placement here subset: vertebrate_core synonym: "fossa" EXACT [] xref: FMA:45791 ! Fossa xref: ZFA:0005388 ! fossa is_a: UBERON:0002553 {source="FMA-implied"} ! anatomical cavity relationship: part_of UBERON:0001474 ! bone element xref: ncithesaurus:Fossa ! Fossa xref: AAO:0010439 ! fossa xref: TAO:0001743 ! fossa xref: VSAO:0005069 ! fossa property_value: external_definition "Anatomical space that is a concavity, shallow depression, or groove on a bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001743", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "concavities" RELATED PLURAL [TAO:0001743] synonym: "concavity" RELATED [TAO:0001743] synonym: "depression" RELATED [TAO:0001743] synonym: "depressions" RELATED PLURAL [TAO:0001743] synonym: "fossae" RELATED PLURAL [TAO:0001743] synonym: "groove" RELATED [TAO:0001743] xref: UMLS:C0836913 [Term] id: UBERON:0004705 ! fenestra name: fenestra def: "an opening in the skull or other bones[WP]." [Wikipedia:Fenestra] comment: TODO check fenestra vs fossa. fenestra = hole, fossa = depression with bottom? is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001474 ! bone element [Term] id: UBERON:0003724 name: musculocutaneous nerve def: "The musculocutaneous nerve arises from the lateral cord of the brachial plexus, opposite the lower border of the Pectoralis minor, its fibers being derived from C5, C6, C7. [WP,unvetted]." [Wikipedia:Musculocutaneous_nerve] synonym: "casserio's nerve" EXACT [FMA:37064] xref: FMA:37064 ! Musculocutaneous nerve xref: GAID:844 ! musculocutaneous nerve xref: OpenCyc:Mx4rvzp0l5wpEbGdrcN5Y29ycA ! musculocutaneous nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Nerves_of_the_left_upper_extremity.gif/200px-Nerves_of_the_left_upper_extremity.gif xref: MESH:A08.800.800.720.050.540 ! musculocutaneous nerve is_a: UBERON:0002003 ! peripheral nerve xref: SCTID:181019000 ! Entire musculocutaneous nerve synonym: "nervus musculocutaneus" RELATED LATIN [Wikipedia:Musculocutaneous_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/a/a7/Nerves_of_the_left_upper_extremity.gif [Term] id: UBERON:0003725 name: cervical plexus def: "The cervical plexus is a plexus of the ventral rami of the first four cervical spinal nerves which are located from C1 to C5 cervical segment in the neck. They are located laterally to the transverse processes between prevertebral muscles from the medial side and vertebral from lateral side. Here there is anastomosis with accessory nerve, hypoglossal nerve and sympathetic trunk. It is located in the neck, deep to sternocleidomastoid. Nerves formed from the cervical plexus innervate the back of the head, as well as some neck muscles. The branches of the cervical plexus emerge from the posterior triangle at the nerve point, a point which lies midway on the posterior border of the Sternocleidomastoid[WP]." [Wikipedia:Cervical_plexus] synonym: "cervical plexus" EXACT [FMA:5904] synonym: "cervical nerve plexus" EXACT [FMA:5904] xref: FMA:5904 ! Cervical nerve plexus xref: GAID:847 ! cervical plexus xref: OpenCyc:Mx4rvkEE3JwpEbGdrcN5Y29ycA ! cervical plexus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/20/Gray784.png/200px-Gray784.png xref: MESH:A08.800.800.720.150 ! cervical plexus is_a: UBERON:0001813 ! somatic nerve plexus synonym: "plexus cervicalis" EXACT LATIN [FMA:TA, FMA:5904] xref: SCTID:181107005 ! Entire cervical plexus synonym: "plexus cervicalis" RELATED LATIN [Wikipedia:Cervical_plexus] xref: http://upload.wikimedia.org/wikipedia/commons/2/20/Gray784.png [Term] id: UBERON:0003726 name: thoracic nerve def: "The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls." [MESH:A08.800.800.720.800] synonym: "pectoral nerve" RELATED [GAID:857] synonym: "thoracic spinal nerve" EXACT [FMA:5860] xref: FMA:5860 ! Thoracic nerve xref: GAID:857 ! thoracic nerve xref: OpenCyc:Mx4rwSJp_ZwpEbGdrcN5Y29ycA ! thoracic spinal nerve xref: MESH:A08.800.800.720.800 ! thoracic nerve (also: UBERON:0003824 'nerve of thoracic segment') is_a: UBERON:0001780 ! spinal nerve xref: SCTID:360498003 ! Entire thoracic spinal nerve [Term] id: UBERON:0009624 name: lumbar nerve def: "The lumbar nerves are the five spinal nerves emerging from the lumbar vertebrae. They are divided into posterior and anterior divisions." [Wikipedia:Lumbar_nerves] synonym: "lumbar spinal nerve" EXACT [FMA:5861] is_a: UBERON:0001780 {source="FMA"} ! spinal nerve xref: FMA:5861 ! lumbar nerve xref: ncithesaurus:Lumbar_Nerve ! Lumbar Nerve synonym: "nervi lumbales" RELATED LATIN [Wikipedia:Lumbar_nerves] xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray802.png xref: SCTID:361600002 ! Entire lumbar spinal nerve xref: UMLS:C0228897 [Term] id: UBERON:0009625 name: sacral nerve def: "The five sacral nerves emerge from the sacrum. Although the vertebral components of the sacrum are fused into a single bone, the sacral vertebrae are still used to number the sacral nerves. Posteriorly, they emerge from the posterior sacral foramina, and form the posterior branches of sacral nerves. Anteriorly, they emerge from the anterior sacral foramina, and contribute to the sacral plexus (S1-S4) and coccygeal plexus." [Wikipedia:Sacral_nerves] synonym: "sacral spinal nerve" EXACT [FMA:5862] is_a: UBERON:0001780 {source="FMA"} ! spinal nerve xref: FMA:5862 ! sacral nerve xref: ncithesaurus:Sacral_Nerve ! Sacral Nerve synonym: "nervi sacrales" RELATED LATIN [Wikipedia:Sacral_nerves] xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray802.png xref: SCTID:361601003 ! Entire sacral spinal nerve xref: UMLS:C0228922 [Term] id: UBERON:0009629 name: coccygeal nerve def: "The coccygeal nerve is the spinal nerve that corresponds to the coccyx bone." [Wikipedia:Coccygeal_nerve] synonym: "coccygeal spinal nerve" EXACT [FMA:5863] is_a: UBERON:0001780 {source="FMA"} ! spinal nerve xref: FMA:5863 ! coccygeal nerve xref: ncithesaurus:Coccygeal_Nerve ! Coccygeal Nerve synonym: "nervus coccygeus" RELATED LATIN [Wikipedia:Coccygeal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray802.png xref: SCTID:287477006 ! Entire coccygeal nerve relationship: in_lateral_side_of UBERON:0000010 {source="FMA-abduced-lr"} ! peripheral nervous system xref: UMLS:C0228967 [Term] id: UBERON:0003727 name: intercostal nerve def: "The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]." [Wikipedia:Intercostal_nerves] synonym: "anterior ramus of thoracic nerve" EXACT [FMA:6028] synonym: "anterior ramus of thoracic spinal nerve" EXACT [FMA:6028] synonym: "ramus anterior, nervus thoracicus" EXACT [FMA:6028] synonym: "thoracic anterior ramus" EXACT [FMA:6028] synonym: "ventral ramus of thoracic spinal nerve" EXACT [FMA:6028] xref: FMA:6028 ! Intercostal nerve xref: GAID:858 ! intercostal nerve xref: ncithesaurus:Intercostal_Nerve ! Intercostal Nerve xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Gray819.png/200px-Gray819.png xref: EMAPA:18227 ! intercostal of nerve of spinal xref: MESH:A08.800.800.720.800.350 ! intercostal nerve is_a: UBERON:0001780 ! spinal nerve xref: SCTID:279568001 ! Entire intercostal nerve synonym: "nervi intercostales" RELATED LATIN [Wikipedia:Intercostal_nerves] xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray819.png xref: UMLS:C1285089 [Term] id: UBERON:0003728 ! mediastinum name: mediastinum def: "The mediastinum is a non-delineated group of structures in the thorax, surrounded by loose connective tissue. It is the central compartment of the thoracic cavity. It contains the heart, the great vessels of the heart, esophagus, trachea, phrenic nerve, cardiac nerve, thoracic duct, thymus, and lymph nodes of the central chest. The mediastinum lies between the right and left pleura in and near the median sagittal plane of the chest. It extends from the sternum in front to the vertebral column behind, and contains all the thoracic viscera except the lungs. It may be divided for purposes of description into two parts:an upper portion, above the upper level of the pericardium, which is named the superior mediastinum with its superior limit at the superior thoracic opening and its inferior limit at the plane from the sternal angle to the disc of T4-T5 (Plane of Ludwig at Angle of Louis); and a lower portion, below the upper level of the pericardium. This lower portion is again subdivided into three parts, viz. that in front of the pericardium, the anterior mediastinum; that containing the pericardium and its contents, the middle mediastinum; and that behind the pericardium, the posterior mediastinum. It is surrounded by the chest wall anteriorly, the lungs laterally and the spine posteriorly. It is continuous with the loose connective tissue of the neck, and extends inferiorly onto the diaphragm." [Wikipedia:Mediastinum] synonym: "mediastinal part of chest" EXACT [FMA:9826] xref: FMA:9826 ! Mediastinum xref: GAID:94 ! mediastinum xref: ncithesaurus:Mediastinum ! Mediastinum xref: OpenCyc:Mx4rv2OKJ5wpEbGdrcN5Y29ycA ! mediastinum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Mediastinum.png/200px-Mediastinum.png xref: MESH:A01.911.800.500 ! mediastinum xref: EFO:0003057 ! mediastinum is_a: UBERON:0002224 ! thoracic cavity xref: SCTID:181217005 ! Entire mediastinum xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png property_value: has_relational_adjective "mediastinal" xsd:string xref: UMLS:C0025066 [Term] id: UBERON:0008818 name: superior mediastinum def: "The superior mediastinum is that portion of the interpleural space which lies between the manubrium sterni in front, and the upper thoracic vertebrae behind." [Wikipedia:Superior_mediastinum] synonym: "superior mediastinal part of chest" EXACT [FMA:9827] is_a: UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0003728 {source="FMA"} ! mediastinum xref: FMA:9827 ! superior mediastinum xref: ncithesaurus:Superior_Mediastinum xref: SCTID:362687003 ! Entire superior mediastinum synonym: "mediastinum superius" RELATED LATIN [Wikipedia:Superior_mediastinum] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png xref: UMLS:C0230147 [Term] id: UBERON:0008819 name: inferior mediastinum def: "Anterior, middle and posterior mediastinum." [Wikipedia:Inferior_mediastinum] synonym: "inferior mediastinal part of chest" EXACT [FMA:9828] is_a: UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0003728 {source="FMA"} ! mediastinum relationship: part_of UBERON:0001443 {source="FMA-propagated"} ! chest xref: FMA:9828 ! inferior mediastinum xref: SCTID:243950006 ! Entire inferior mediastinum [Term] id: UBERON:0008820 name: anterior mediastinum def: "The anterior mediastinum exists only on the left side where the left pleura diverges from the mid-sternal line. It is narrow, above, but widens out a little below." [Wikipedia:Anterior_mediastinum] synonym: "anterior mediastinal part of chest" EXACT [FMA:9838] is_a: UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0008819 {source="FMA"} ! inferior mediastinum xref: FMA:9838 ! anterior mediastinum xref: ncithesaurus:Anterior_Mediastinum ! Anterior Mediastinum xref: SCTID:261048003 ! Entire anterior mediastinum synonym: "mediastinum anterius" RELATED LATIN [Wikipedia:Anterior_mediastinum] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png xref: UMLS:C0230148 [Term] id: UBERON:0008821 name: middle mediastinum def: "The middle mediastinum is the broadest part of the interpleural space. It is made up of the pericardial sac and its contents." [Wikipedia:Middle_mediastinum] synonym: "middle mediastinal part of chest" EXACT [FMA:9839] is_a: UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0008819 {source="FMA"} ! inferior mediastinum xref: FMA:9839 ! middle mediastinum xref: ncithesaurus:Middle_Mediastinum ! Middle Mediastinum xref: SCTID:362688008 ! Entire middle mediastinum synonym: "mediastinum medium" RELATED LATIN [Wikipedia:Middle_mediastinum] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png xref: UMLS:C0230149 [Term] id: UBERON:0008822 name: posterior mediastinum def: "The posterior mediastinum is an irregular triangular space running parallel with the vertebral column." [Wikipedia:Posterior_mediastinum] synonym: "posterior mediastinal part of chest" EXACT [FMA:9840] is_a: UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0008819 {source="FMA"} ! inferior mediastinum xref: FMA:9840 ! posterior mediastinum xref: ncithesaurus:Posterior_Mediastinum ! Posterior Mediastinum xref: SCTID:243957009 ! Entire posterior mediastinum synonym: "mediastinum posterius" RELATED LATIN [Wikipedia:Posterior_mediastinum] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png xref: UMLS:C0230150 [Term] id: UBERON:0003824 name: nerve of thoracic segment def: "A nerve that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of thorax" EXACT [OBOL:automatic] synonym: "thorax nerve" EXACT [OBOL:automatic] synonym: "upper body nerve" RELATED [MA:0000562] synonym: "thoracic segment nerve" EXACT [MA:0000562] xref: MA:0000562 ! thoracic segment nerve xref: MESH:A08.800.800.720.800 ! thoracic nerve (also: UBERON:0003726 'thoracic nerve') intersection_of: UBERON:0001021 intersection_of: part_of UBERON:0000915 xref: SCTID:359876006 ! Nervous structure of thorax [Term] id: UBERON:0003825 name: nerve of abdominal segment def: "A nerve that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] xref: MA:0000528 ! abdominal segment nerve synonym: "abdominal segment nerve" EXACT [MA:0000528] intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0003826 name: upper leg bone def: "A bone that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: MA:0000682 ! upper leg bone intersection_of: UBERON:0001474 intersection_of: part_of UBERON:0000376 [Term] id: UBERON:0003827 name: thoracic segment bone def: "A bone that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "bone of thorax" EXACT [OBOL:automatic] synonym: "bone organ of thorax" EXACT [OBOL:automatic] synonym: "thorax bone" EXACT [OBOL:automatic] synonym: "thorax bone organ" EXACT [OBOL:automatic] synonym: "upper body bone" RELATED [MA:0000559] xref: MA:0000559 intersection_of: UBERON:0001474 intersection_of: part_of UBERON:0000915 xref: SCTID:426649006 ! Entire bone organ of thorax [Term] id: UBERON:0003828 name: abdominal segment bone def: "A bone that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk bone" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk bone organ" EXACT [OBOL:automatic] synonym: "bone of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "bone organ of abdominal segment of trunk" EXACT [OBOL:automatic] xref: MA:0000525 intersection_of: UBERON:0001474 intersection_of: part_of UBERON:0002417 [Term] id: UBERON:0003829 name: urethra muscle def: "A muscle organ that is part of a urethra [Automatically generated definition]." [OBOL:automatic] comment: AO notes: FMA class may not be equivalent synonym: "muscle organ of urethra" EXACT [OBOL:automatic] synonym: "urethra muscle organ" EXACT [OBOL:automatic] synonym: "urethral muscle layer" RELATED [MA:0002649] synonym: "muscle layer of urethra" RELATED [FMA:76909] xref: MA:0002649 xref: FMA:76909 ! muscle layer of urethra intersection_of: UBERON:0001630 intersection_of: part_of UBERON:0000057 synonym: "muscular coat of urethra" EXACT [FMA:76909] synonym: "muscular layer of urethra" EXACT [FMA:76909] [Term] id: UBERON:0003830 name: thoracic segment muscle def: "A muscle organ that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "muscle organ of thorax" EXACT [OBOL:automatic] synonym: "thorax muscle organ" EXACT [OBOL:automatic] synonym: "upper body muscle" RELATED [MA:0000561] xref: MA:0000561 ! thoracic segment muscle intersection_of: UBERON:0001630 intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0003831 name: respiratory system muscle def: "A muscle organ that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "muscle organ of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system muscle organ" EXACT [OBOL:automatic] xref: MA:0001828 intersection_of: UBERON:0001630 intersection_of: part_of UBERON:0001004 [Term] id: UBERON:0003832 name: esophagus muscle def: "A muscle organ that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] comment: Editor notes: merge muscle and muscle layer? synonym: "esophagus muscle organ" EXACT [OBOL:automatic] synonym: "gullet muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of esophagus" EXACT [OBOL:automatic] synonym: "muscle organ of gullet" EXACT [OBOL:automatic] synonym: "muscle organ of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus muscle organ" EXACT [OBOL:automatic] synonym: "esophageal muscle" EXACT [] xref: MA:0002682 xref: SCTID:360961009 ! esophageal muscle intersection_of: UBERON:0001630 intersection_of: part_of UBERON:0001043 relationship: part_of UBERON:0001096 {source="MA"} ! wall of esophagus [Term] id: UBERON:0011878 name: muscle layer of esophagus def: "A muscle layer that is part of a wall of esophagus." [OBOL:automatic] synonym: "muscle coat of esophagus" EXACT [FMA:62998] synonym: "muscular coat of oesophagus" EXACT [FMA:62998] synonym: "muscular layer of oesophagus" EXACT [FMA:62998] synonym: "tunica muscularis oesophageae" EXACT LATIN [FMA:TA] synonym: "tunica muscularis esophagi" EXACT LATIN [] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 ! wall of esophagus relationship: has_part UBERON:0001134 {source="Wikipedia:Muscular_layer", notes="upper part"} ! skeletal muscle tissue xref: FMA:62998 ! muscle layer of esophagus [Term] id: UBERON:0009960 name: esophagus smooth muscle circular layer synonym: "esophagus smooth muscle circular layer" RELATED [MA:0001574] intersection_of: UBERON:0012368 ! circular muscle layer intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0002112 {source="MA"} ! smooth muscle of esophagus xref: MA:0001574 ! esophagus smooth muscle circular layer xref: FMA:67605 ! circular muscle layer of esophagus synonym: "circular muscle layer of esophagus" EXACT [FMA:67605] synonym: "inner circular muscle layer of esophagus" EXACT [FMA:67605] [Term] id: UBERON:0009961 name: esophagus smooth muscle longitudinal layer synonym: "esophagus smooth muscle longitudinal layer" RELATED [MA:0001575] synonym: "longitudinal muscle layer of esophagus" EXACT [FMA:63573] is_a: UBERON:0012369 ! longitudinal muscle layer relationship: part_of UBERON:0002112 {source="MA"} ! smooth muscle of esophagus relationship: part_of UBERON:0003832 {source="FMA"} ! esophagus muscle xref: MA:0001575 ! esophagus smooth muscle longitudinal layer xref: FMA:63573 ! longitudinal muscle layer of esophagus synonym: "outer longitudinal muscle layer of esophagus" EXACT [FMA:63573] [Term] id: UBERON:0003834 name: thoracic segment blood vessel def: "A blood vessel that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of thorax" EXACT [OBOL:automatic] synonym: "thorax blood vessel" EXACT [OBOL:automatic] synonym: "upper body blood vessel" RELATED [MA:0000558] xref: MA:0000558 intersection_of: UBERON:0001981 intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0003835 name: abdominal segment blood vessel def: "A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of abdominal segment of trunk" EXACT [OBOL:automatic] xref: MA:0000524 intersection_of: UBERON:0001981 intersection_of: part_of UBERON:0002417 [Term] id: UBERON:0003837 name: thoracic segment connective tissue def: "A portion of connective tissue that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of thorax" EXACT [OBOL:automatic] synonym: "portion of connective tissue of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of thorax" EXACT [OBOL:automatic] synonym: "thorax connective tissue" EXACT [OBOL:automatic] synonym: "thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "thorax textus connectivus" EXACT [OBOL:automatic] synonym: "upper body connective tissue" RELATED [MA:0000560] xref: MA:0000560 intersection_of: UBERON:0002384 intersection_of: part_of UBERON:0000915 [Term] id: UBERON:0003838 name: abdominal segment connective tissue def: "A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk connective tissue" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of abdominal segment of trunk" EXACT [OBOL:automatic] xref: MA:0000526 intersection_of: UBERON:0002384 intersection_of: part_of UBERON:0002417 [Term] id: UBERON:0003839 name: forelimb joint def: "A limb joint that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing joint" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "anteriormost limb joint of limb" EXACT [OBOL:automatic] synonym: "anteriormost limb limb joint" EXACT [OBOL:automatic] synonym: "fore limb joint of limb" EXACT [OBOL:automatic] synonym: "fore limb limb joint" EXACT [OBOL:automatic] synonym: "forelimb joint of limb" EXACT [OBOL:automatic] synonym: "forelimb limb joint" EXACT [OBOL:automatic] synonym: "joint of limb of anteriormost limb" EXACT [OBOL:automatic] synonym: "joint of limb of fore limb" EXACT [OBOL:automatic] synonym: "joint of limb of forelimb" EXACT [OBOL:automatic] synonym: "joint of limb of superior member" EXACT [OBOL:automatic] synonym: "joint of limb of upper extremity" EXACT [OBOL:automatic] synonym: "limb joint of anteriormost limb" EXACT [OBOL:automatic] synonym: "limb joint of fore limb" EXACT [OBOL:automatic] synonym: "limb joint of forelimb" EXACT [OBOL:automatic] synonym: "limb joint of superior member" EXACT [OBOL:automatic] synonym: "limb joint of upper extremity" EXACT [OBOL:automatic] synonym: "superior member joint of limb" EXACT [OBOL:automatic] synonym: "superior member limb joint" EXACT [OBOL:automatic] synonym: "upper extremity joint of limb" EXACT [OBOL:automatic] synonym: "upper extremity limb joint" EXACT [OBOL:automatic] xref: MA:0000614 xref: EMAPA:19204 ! joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002102 [Term] id: UBERON:0003840 name: hindlimb joint def: "A limb joint that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "joint of lower limb" EXACT [UBERON:cjm] synonym: "hind limb joint of limb" EXACT [OBOL:automatic] synonym: "hind limb limb joint" EXACT [OBOL:automatic] synonym: "hindlimb joint of limb" EXACT [OBOL:automatic] synonym: "hindlimb limb joint" EXACT [OBOL:automatic] synonym: "inferior member joint of limb" EXACT [OBOL:automatic] synonym: "inferior member limb joint" EXACT [OBOL:automatic] synonym: "joint of limb of hind limb" EXACT [OBOL:automatic] synonym: "joint of limb of hindlimb" EXACT [OBOL:automatic] synonym: "joint of limb of inferior member" EXACT [OBOL:automatic] synonym: "joint of limb of lower extremity" EXACT [OBOL:automatic] synonym: "limb joint of hind limb" EXACT [OBOL:automatic] synonym: "limb joint of hindlimb" EXACT [OBOL:automatic] synonym: "limb joint of inferior member" EXACT [OBOL:automatic] synonym: "limb joint of lower extremity" EXACT [OBOL:automatic] synonym: "lower extremity joint of limb" EXACT [OBOL:automatic] synonym: "lower extremity limb joint" EXACT [OBOL:automatic] xref: MA:0000662 ! hindlimb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002103 ! hindlimb xref: SCTID:304573000 ! Entire joint of lower limb [Term] id: UBERON:0003841 name: autopod joint def: "A limb joint that is part of an autopod [Automatically generated definition]." [OBOL:automatic] synonym: "autopod joint of limb" EXACT [OBOL:automatic] synonym: "autopod limb joint" EXACT [OBOL:automatic] synonym: "distal free limb segment joint of limb" EXACT [OBOL:automatic] synonym: "distal free limb segment limb joint" EXACT [OBOL:automatic] synonym: "joint of limb of autopod" EXACT [OBOL:automatic] synonym: "joint of limb of distal free limb segment" EXACT [OBOL:automatic] synonym: "limb joint of autopod" EXACT [OBOL:automatic] synonym: "limb joint of distal free limb segment" EXACT [OBOL:automatic] synonym: "paw joint" RELATED [MA:0002715] xref: MA:0002715 ! autopod joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002470 [Term] id: UBERON:0003844 name: upper eyelid epithelium def: "An epithelium that is part of a upper eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of superior eyelid" EXACT [OBOL:automatic] synonym: "epithelial tissue of upper eyelid" EXACT [OBOL:automatic] synonym: "epithelium of superior eyelid" EXACT [OBOL:automatic] synonym: "epithelium of upper eyelid" EXACT [OBOL:automatic] synonym: "superior eyelid epithelial tissue" EXACT [OBOL:automatic] synonym: "superior eyelid epithelium" EXACT [OBOL:automatic] synonym: "upper eyelid epithelial tissue" EXACT [OBOL:automatic] xref: VHOG:0000638 xref: EHDAA2:0002116 ! upper eyelid epithelium xref: EMAPA:17835 ! epithelium of upper of eyelid intersection_of: UBERON:0000483 intersection_of: part_of UBERON:0001712 [Term] id: UBERON:0003845 name: lower eyelid epithelium def: "An epithelium that is part of a lower eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of inferior eyelid" EXACT [OBOL:automatic] synonym: "epithelial tissue of lower eyelid" EXACT [OBOL:automatic] synonym: "epithelium of inferior eyelid" EXACT [OBOL:automatic] synonym: "epithelium of lower eyelid" EXACT [OBOL:automatic] synonym: "inferior eyelid epithelial tissue" EXACT [OBOL:automatic] synonym: "inferior eyelid epithelium" EXACT [OBOL:automatic] synonym: "lower eyelid epithelial tissue" EXACT [OBOL:automatic] xref: VHOG:0000637 xref: EHDAA2:0001016 ! lower eyelid epithelium xref: EMAPA:17832 ! epithelium of lower of eyelid intersection_of: UBERON:0000483 intersection_of: part_of UBERON:0001713 [Term] id: UBERON:0003846 name: thymus epithelium def: "the supporting framework of the thymus." [MP:0009544] synonym: "epithelial tissue of thymus" EXACT [OBOL:automatic] synonym: "epithelial tissue of thymus gland" EXACT [OBOL:automatic] synonym: "epithelium of thymus" EXACT [OBOL:automatic] synonym: "epithelium of thymus gland" EXACT [OBOL:automatic] synonym: "thymus epithelial tissue" EXACT [OBOL:automatic] synonym: "thymus gland epithelial tissue" EXACT [OBOL:automatic] synonym: "thymus gland epithelium" EXACT [OBOL:automatic] synonym: "thymic epithelium" EXACT [BTO:0001836] synonym: "thymic epithelial tissue" EXACT [] xref: VHOG:0001426 xref: MA:0000768 ! thymus epithelium xref: EHDAA2:0002019 ! thymus epithelium xref: BTO:0001836 ! thymic epithelium xref: ncithesaurus:Thymic_Epithelial_Tissue ! Thymic Epithelial Tissue intersection_of: UBERON:0000483 intersection_of: part_of UBERON:0002370 ! thymus relationship: has_part PR:000007636 {source="PMID:21293377"} ! forkhead box protein N1 xref: UMLS:C1711423 [Term] id: UBERON:0003847 name: thyroid artery xref: VHOG:0001366 xref: MA:0002066 ! thyroid artery xref: ncithesaurus:Thyroid_Artery ! Thyroid Artery xref: EHDAA:7372 ! thyroid artery xref: EHDAA2:0002029 ! thyroid artery xref: EMAPA:18622 ! thyroid artery is_a: UBERON:0001637 ! artery xref: AAO:0010490 ! thyroid artery property_value: external_definition "Part of the external carotid which supplies blood to the thyroid gland.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010490", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of external carotid (AAO:0010218)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010490", date_retrieved="2012-06-20"} xref: UMLS:C1711424 [Term] id: UBERON:0003848 name: gonadal vein def: "In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]." [Wikipedia:Gonadal_vein] synonym: "gonad vein" EXACT [OBOL:automatic] synonym: "gonada vein" EXACT [OBOL:automatic] synonym: "vein of gonad" EXACT [OBOL:automatic] synonym: "vein of gonada" EXACT [OBOL:automatic] xref: VHOG:0001340 xref: EHDAA:8703 ! gonadal vein xref: OpenCyc:Mx4rvlWYh5wpEbGdrcN5Y29ycA ! gonadal vein xref: EHDAA2:0000719 ! gonadal vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Gray1120.png/200px-Gray1120.png intersection_of: UBERON:0001638 intersection_of: attaches_to UBERON:0000991 xref: SCTID:278192008 ! Gonadal vein xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png [Term] id: UBERON:0003849 name: mesencephalic neural crest subset: vertebrate_core synonym: "mesencephalic neural crest" EXACT [ZFA:0000935] xref: VHOG:0000796 xref: ZFA:0000935 ! neural crest midbrain synonym: "neural crest midbrain" EXACT [ZFA:0000935] xref: EHDAA2:0001101 ! mesencephalic neural crest xref: EHDAA:360 ! mesencephalic neural crest xref: EFO:0003591 ! neural crest midbrain is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest intersection_of: UBERON:0002342 intersection_of: developmentally_contributes_to UBERON:0001891 xref: TAO:0000935 ! neural crest midbrain property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000796", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A neural crest that developmentally_contributes_to a midbrain." [OBOL:automatic] [Term] id: UBERON:0003850 name: telencephalon neural crest subset: vertebrate_core xref: VHOG:0000799 xref: ZFA:0000812 ! neural crest telencephalon synonym: "neural crest telencephalon" EXACT [ZFA:0000812] xref: RETIRED_EHDAA2:0001991 ! telencephalon neural crest xref: EFO:0003574 ! neural crest telencephalon intersection_of: UBERON:0002342 intersection_of: developmentally_contributes_to UBERON:0001893 xref: TAO:0000812 ! neural crest telencephalon property_value: external_definition "Cranial neural crest that is part of the telencephalon.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000812", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000799", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A neural crest that developmentally_contributes_to a telencephalon." [OBOL:automatic] [Term] id: UBERON:0003851 name: diencephalon neural crest synonym: "diencephalic neural crest" EXACT [ZFA:0000811] synonym: "future diencephalon neural crest" EXACT [EHDAA2:0000603] xref: VHOG:0000798 xref: ZFA:0000811 ! neural crest diencephalon synonym: "neural crest diencephalon" EXACT [ZFA:0000811] xref: EFO:0003573 ! neural crest diencephalon xref: EHDAA2:0000603 ! future diencephalon neural crest xref: EMAPA:16518 ! neural crest of future diencephalon synonym: "neural crest of future diencephalon" EXACT [EMAPA:16518] intersection_of: UBERON:0002342 intersection_of: developmentally_contributes_to UBERON:0001894 xref: TAO:0000811 ! neural crest diencephalon property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000798", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A neural crest that developmentally_contributes_to a diencephalon." [OBOL:automatic] [Term] id: UBERON:0003852 name: rhombencephalon neural crest subset: vertebrate_core synonym: "neural crest hindbrain" EXACT [ZFA:0007063] synonym: "rhombencephalic neural crest" EXACT [ZFA:0007063] xref: VHOG:0001210 xref: ZFA:0007063 ! neural crest hindbrain xref: EHDAA2:0001628 ! rhombencephalic neural crest xref: EHDAA:362 ! rhombencephalic neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: developmentally_contributes_to UBERON:0002028 xref: TAO:0007063 ! neural crest hindbrain property_value: external_definition "Cranial neural crest that is part of the hindbrain.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0007063", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001210", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A neural crest that developmentally_contributes_to a hindbrain." [OBOL:automatic] [Term] id: UBERON:0003853 name: spinal cord neural crest xref: VHOG:0001006 intersection_of: UBERON:0002342 intersection_of: developmentally_contributes_to UBERON:0002240 xref: EHDAA:696 xref: EMAPA:16094 ! neural crest of neural fold of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16163 ! neural crest of neural fold of neural plate of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16529 ! neural crest of neural fold of neural plate of future spinal cord of central nervous system of nervous system of organ system xref: EMAPA:16881 ! neural crest of neural plate of future spinal cord of central nervous system of nervous system of tail of embryo synonym: "neural crest spinal cord" EXACT [VHOG:0001006] synonym: "spinal neural crest" RELATED [VHOG:0001006] property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...)[well established][VHOG]" xsd:string {external_class="VHOG:0001006", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A neural crest that developmentally_contributes_to a spinal cord." [OBOL:automatic] [Term] id: UBERON:0003854 name: spinal cord neural plate synonym: "neural plate of spinal cord" EXACT [OBOL:automatic] xref: VHOG:0000439 xref: ZFA:0007021 ! spinal cord neural plate intersection_of: UBERON:0003075 ! neural plate intersection_of: develops_from UBERON:0006241 ! future spinal cord relationship: immediate_transformation_of UBERON:0006241 {source="ZFA"} ! future spinal cord xref: TAO:0007021 ! spinal cord neural plate property_value: external_definition "Neural plate that is part of the spinal cord. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000439", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...)[well established][VHOG]" xsd:string {external_class="VHOG:0000439", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A neural plate that develops_from a future spinal cord." [OBOL:automatic] [Term] id: UBERON:0009610 name: forebrain neural plate xref: TAO:0007018 ! forebrain neural plate intersection_of: UBERON:0003075 ! neural plate intersection_of: develops_from UBERON:0006240 {source="ZFA"} ! future forebrain relationship: part_of UBERON:0003056 {source="ZFA"} ! pre-chordal neural plate xref: ZFA:0007018 ! forebrain neural plate def: "A neural plate that develops_from a future forebrain." [OBOL:automatic] [Term] id: UBERON:0009611 name: midbrain neural plate xref: TAO:0007019 ! midbrain neural plate intersection_of: UBERON:0003075 ! neural plate intersection_of: develops_from UBERON:0009616 {source="ZFA"} ! presumptive midbrain relationship: part_of UBERON:0003056 {source="ZFA"} ! pre-chordal neural plate xref: ZFA:0007019 ! midbrain neural plate def: "A neural plate that develops_from a presumptive midbrain." [OBOL:automatic] [Term] id: UBERON:0009612 name: forebrain midbrain boundary neural plate xref: TAO:0007020 ! forebrain midbrain boundary neural plate is_a: UBERON:0006800 {source="ZFA"} ! anatomical line relationship: develops_from UBERON:0007288 {source="ZFA"} ! presumptive forebrain midbrain boundary relationship: part_of UBERON:0003056 {source="ZFA"} ! pre-chordal neural plate xref: ZFA:0007020 ! forebrain midbrain boundary neural plate [Term] id: UBERON:0009614 name: hindbrain neural plate xref: TAO:0007022 ! hindbrain neural plate intersection_of: UBERON:0003075 ! neural plate intersection_of: develops_from UBERON:0007277 {source="ZFA"} ! presumptive hindbrain relationship: part_of UBERON:0003057 {source="ZFA"} ! chordal neural plate xref: ZFA:0007022 ! hindbrain neural plate def: "A neural plate that develops_from a presumptive hindbrain." [OBOL:automatic] [Term] id: UBERON:0004883 name: lung mesenchyme def: "the mass of tissue made up of mesenchymal cells in the lung." [GO:0060484] synonym: "lung-associated mesenchyme" EXACT [GO:0060484] synonym: "pulmonary mesenchyme" EXACT [GO:0060484] synonym: "mesenchyme of lung" EXACT [OBOL:automatic] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002048 ! lung relationship: develops_from UBERON:0003081 ! lateral plate mesoderm [Term] id: UBERON:0009602 name: left lung associated mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002168 ! left lung xref: EHDAA2:0000944 ! left lung associated mesenchyme xref: EMAPA:16730 ! associated mesenchyme of left lung rudiment xref: EMAPA:17654 ! associated mesenchyme of left lung def: "Mesenchyme that is part of a left lung." [OBOL:automatic] [Term] id: UBERON:0009603 name: right lung associated mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002167 ! right lung xref: EHDAA2:0001739 ! right lung associated mesenchyme xref: EMAPA:17662 ! associated mesenchyme of right lung def: "Mesenchyme that is part of a right lung." [OBOL:automatic] [Term] id: UBERON:0004884 ! lobar bronchus mesenchyme name: lobar bronchus mesenchyme def: "the mass of tissue composed of mesenchymal cells in the lobar bronchus.." [GO:0060483] synonym: "mesenchyme of lobar bronchus" EXACT [OBOL:automatic] intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0002183 ! lobar bronchus [Term] id: UBERON:0003855 name: gonad mesenchyme def: "Mesenchyme that is part of a gonad [Automatically generated definition]." [OBOL:automatic] synonym: "gonada mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of gonad" EXACT [OBOL:automatic] synonym: "mesenchyme of gonada" EXACT [OBOL:automatic] xref: VHOG:0001090 xref: EMAPA:16858 ! gonadal mesenchyme of gonad of genitourinary system xref: EMAPA:17385 ! gonadal mesenchyme of gonad of reproductive system xref: EHDAA:5012 ! mesenchyme of gonadal intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0000991 [Term] id: UBERON:0010330 name: eyelid mesenchyme intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0001711 ! eyelid def: "Mesenchyme that is part of a eyelid." [OBOL:automatic] [Term] id: UBERON:0003857 name: upper eyelid mesenchyme def: "Mesenchyme that is part of a upper eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme of superior eyelid" EXACT [OBOL:automatic] synonym: "mesenchyme of upper eyelid" EXACT [OBOL:automatic] synonym: "superior eyelid mesenchyme" EXACT [OBOL:automatic] xref: VHOG:0001093 xref: EHDAA2:0002117 ! upper eyelid mesenchyme xref: EHDAA:9051 ! mesenchyme of upper of eyelid intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0001712 relationship: develops_from UBERON:0003314 {source="EHDAA2"} ! eye mesenchyme [Term] id: UBERON:0003858 name: lower eyelid mesenchyme def: "Mesenchyme that is part of a lower eyelid [Automatically generated definition]." [OBOL:automatic] synonym: "inferior eyelid mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of inferior eyelid" EXACT [OBOL:automatic] synonym: "mesenchyme of lower eyelid" EXACT [OBOL:automatic] xref: VHOG:0001036 xref: EHDAA2:0001017 ! lower eyelid mesenchyme xref: EHDAA:9045 ! mesenchyme of lower of eyelid intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0001713 relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm [Term] id: UBERON:0003859 name: forelimb mesenchyme def: "Mesenchyme that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing mesenchyme" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "wing mesenchyme" NARROW SENSU [Geisha:syn, NCBITaxon:8782] synonym: "anteriormost limb mesenchyme" EXACT [OBOL:automatic] synonym: "fore limb mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of anteriormost limb" EXACT [OBOL:automatic] synonym: "mesenchyme of fore limb" EXACT [OBOL:automatic] synonym: "mesenchyme of forelimb" EXACT [OBOL:automatic] synonym: "mesenchyme of superior member" EXACT [OBOL:automatic] synonym: "mesenchyme of upper extremity" EXACT [OBOL:automatic] synonym: "superior member mesenchyme" EXACT [OBOL:automatic] synonym: "upper extremity mesenchyme" EXACT [OBOL:automatic] xref: VHOG:0001109 intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0002102 [Term] id: UBERON:0003860 name: hindlimb mesenchyme def: "Mesenchyme that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb mesenchyme" EXACT [OBOL:automatic] synonym: "inferior member mesenchyme" EXACT [OBOL:automatic] synonym: "lower extremity mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of hind limb" EXACT [OBOL:automatic] synonym: "mesenchyme of hindlimb" EXACT [OBOL:automatic] synonym: "mesenchyme of inferior member" EXACT [OBOL:automatic] synonym: "mesenchyme of lower extremity" EXACT [OBOL:automatic] xref: VHOG:0001074 intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0002103 [Term] id: UBERON:0003869 name: presumptive ganglion intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0000045 ! ganglion def: "A presumptive structure that develops_into a ganglion." [OBOL:automatic] [Term] id: UBERON:0003874 name: obsolete presumptive ventricle is_obsolete: true [Term] id: UBERON:0002136 name: hilus of dentate gyrus comment: Merge with CA4? synonym: "dentate gyrus hilus" EXACT [] synonym: "field CA4 of hippocampal formation" EXACT [] synonym: "CA4" RELATED [] xref: FMA:72358 ! Hilus of dentate gyrus xref: MA:0000947 ! dentate gyrus hilus xref: NIF_GrossAnatomy:birnlex_1482 ! Hilus of dentate gyrus is_a: UBERON:0002744 ! hilum of dentate nucleus relationship: part_of UBERON:0001885 ! dentate gyrus of hippocampal formation [Term] id: UBERON:0002744 name: hilum of dentate nucleus synonym: "dentate nuclear hilum" EXACT [FMA:72548] xref: FMA:72548 ! Hilum of dentate nucleus xref: NIF_GrossAnatomy:birnlex_1561 ! Hilum of dentate nucleus is_a: UBERON:0002316 ! white matter of neuraxis xref: SCTID:369055003 ! Entire hilum of dentate nucleus [Term] id: UBERON:0001152 name: cystic duct def: "The cystic duct is the short duct that joins the gall bladder to the common bile duct. It usually lies next to the cystic artery. It is of variable length. It contains a 'spiral valve', which does not provide much resistance to the flow of bile. [WP,unvetted]." [Wikipedia:Cystic_duct] subset: uberon_slim subset: vertebrate_core xref: EHDAA:3045 ! cystic duct xref: FMA:14539 ! Cystic duct xref: GAID:290 ! cystic duct xref: galen:CysticDuct xref: VHOG:0000213 ! cystic duct xref: MA:0000355 ! cystic duct xref: OpenCyc:Mx4rveBeC5wpEbGdrcN5Y29ycA xref: ZFA:0005166 ! cystic duct xref: ncithesaurus:Cystic_Duct ! Cystic Duct xref: OpenCyc:Mx4rveBeC5wpEbGdrcN5Y29ycA ! cystic duct xref: EHDAA2:0000333 ! cystic duct xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5d/Digestive_system_showing_bile_duct.png/200px-Digestive_system_showing_bile_duct.png xref: EMAPA:16841 ! cystic duct xref: MESH:A03.159.183.419 ! cystic duct is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct relationship: part_of UBERON:0001173 {source="FMA"} ! biliary tree relationship: develops_from UBERON:0005604 {source="EHDAA2"} ! hepatic duct extrahepatic part relationship: continuous_with UBERON:0001174 ! common bile duct relationship: continuous_with UBERON:0002110 ! gallbladder relationship: channel_for UBERON:0001970 ! bile relationship: channels_into UBERON:0001174 ! common bile duct xref: SCTID:245398005 ! Entire cystic duct xref: TAO:0005166 ! cystic duct synonym: "ductus cysticus" RELATED LATIN [Wikipedia:Cystic_duct] xref: http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg property_value: external_definition "Duct that connects the gall bladder and the common bile duct.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005166", date_retrieved="2012-08-14", source="ZFIN:Curator"} property_value: external_definition "The duct of the gallbladder which joins the common hepatic duct, thus forming the common biliary duct. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000213", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0010672 [Term] id: UBERON:0008836 ! liver bud name: liver bud xref: BTO:0001642 ! liver bud is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0008835 {source="http://www.stembook.org/node/512"} ! hepatic diverticulum [Term] id: UBERON:0004912 name: biliary bud synonym: "hepatic diverticulum" RELATED [EMAPA:16561] xref: EMAPA:16561 ! biliary bud xref: EMAPA:16565 ! hepatic diverticulum xref: VHOG:0001351 ! biliary bud xref: EHDAA2:0000171 ! biliary bud xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4f/Gray1088.png/200px-Gray1088.png is_a: UBERON:0003914 ! epithelial tube relationship: part_of UBERON:0006235 {source="EMAPA"} ! foregut-midgut junction relationship: develops_from UBERON:0004161 {source="EHDAA2-modified"} ! septum transversum [Term] id: UBERON:0008835 ! hepatic diverticulum name: hepatic diverticulum def: "The first morphological sign of the embryonic liver is the formation of the hepatic diverticulum, an out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile duct." [http://www.stembook.org/node/512, Wikipedia:Hepatic_diverticulum] synonym: "liver diverticulum" EXACT [XAO:0000101] is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0006235 {source="EHDAA2"} ! foregut-midgut junction relationship: develops_from UBERON:0003894 {source="EHDAA2"} ! liver primordium xref: XAO:0000101 ! liver diverticulum xref: AAO:0011057 ! liver diverticulum xref: EHDAA:1530 ! hepatic diverticulum xref: EHDAA2:0000740 ! hepatic diverticulum xref: ncithesaurus:Hepatic_Diverticulum ! Hepatic Diverticulum synonym: "diverticulum hepaticum" RELATED LATIN [Wikipedia:Hepatic_diverticulum] xref: http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png xref: UMLS:C1512407 [Term] id: UBERON:0003894 ! liver primordium name: liver primordium def: "A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum." [ISBN:3211492755] comment: Editor's note: consider adding further subdivisions of the endoderm, e.g. ventral foregut. Note we place two EFO classes here, it's not clear how they differ subset: vertebrate_core synonym: "liver bud" RELATED INCONSISTENT [ZFA:0000124, XAO:0003266] synonym: "hepatic plate" RELATED [EHDAA2:0000744] synonym: "embryological hepatic plate" EXACT [UBERON:cjm] synonym: "primordium of the liver" EXACT [ncithesaurus:Primordium_of_the_Liver] synonym: "liver endoderm" RELATED [EFO:0002577] xref: XAO:0003266 ! liver primordium xref: ZFA:0000124 ! liver primordium xref: EMAPA:16847 ! hepatic primordium xref: EFO:0003428 ! liver primordium xref: EFO:0002577 ! liver endoderm xref: EHDAA2:0000744 ! hepatic plate xref: EHDAA:973 ! hepatic plate is_a: UBERON:0001048 {source="XAO"} ! primordium is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium intersection_of: UBERON:0001048 ! primordium intersection_of: develops_into UBERON:0002107 ! liver relationship: part_of UBERON:0009550 {source="EHDAA2"} ! endoderm of foregut-midgut junction relationship: develops_from UBERON:0001041 {notes="ventral foregut endoderm", source="Zaret 1996"} ! foregut xref: ncithesaurus:Primordium_of_the_Liver ! Primordium of the Liver xref: ncithesaurus:Hepatic_Cord ! Hepatic Cord disjoint_from: UBERON:0005452 ! hepatic plate xref: AAO:0011058 ! liver primordium xref: TAO:0000124 ! liver primordium xref: BTO:0003391 ! hepatic primordium xref: UMLS:C0734013 xref: UMLS:C1514451 [Term] id: UBERON:0003896 name: obsolete muscle of body wall def: "A muscle organ that is part of a body wall [Automatically generated definition]." [OBOL:automatic] comment: obsoleted as it grouped together a worm-specific structure (BTO) with the vertebrate structure (which develops from the myotome) is_obsolete: true synonym: "wall muscle" RELATED [BTO:0001863] consider: BTO:0001863 ! body wall muscle consider: ANISEED:1235296 ! Body wall muscle consider: UBERON:0004462 ! musculature of body wall consider: WBbt:0005813 [Term] id: UBERON:0004462 ! musculature of body wall name: musculature of body wall def: "A musculature that is part of a body wall [Automatically generated definition]." [OBOL:automatic] synonym: "body wall musculature" EXACT [FMA:86931] synonym: "body wall muscles" RELATED [] xref: FMA:86931 ! Musculature of body wall intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000309 ! body wall [Term] id: UBERON:0008713 name: pectoral girdle and thoracic body wall skeletal muscle xref: RETIRED_EHDAA2:0001422 ! pectoral girdle and thoracic body wall skeletal muscle is_a: UBERON:0001134 ! skeletal muscle tissue xref: EHDAA2:0001421 ! pectoral girdle and thoracic body wall muscle system [Term] id: UBERON:0003897 name: axial muscle def: "A skeletal muscle of the trunk or head." [] xref: EHDAA:5982 ! axial muscle xref: RETIRED_EHDAA2:0000160 ! axial skeletal muscle xref: EMAPA:18166 ! axial muscle xref: EMAPA:18167 ! skeletal muscle of axial muscle is_a: UBERON:0001134 ! skeletal muscle tissue union_of: UBERON:0003898 union_of: UBERON:0003899 xref: EHDAA2:0000159 ! axial muscle system xref: TAO:0001954 ! axial muscle [Term] id: UBERON:0003898 name: skeletal muscle of trunk def: "A skeletal muscle of the trunk." [] synonym: "skeletal muscle of torso" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of torso" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of trunk" EXACT [OBOL:automatic] synonym: "torso skeletal muscle" EXACT [OBOL:automatic] synonym: "torso skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "trunk skeletal muscle" EXACT [OBOL:automatic] synonym: "trunk skeletal muscle tissue" EXACT [OBOL:automatic] intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002100 ! trunk xref: SCTID:244848007 ! Entire skeletal muscle of trunk relationship: part_of UBERON:0004479 {source="reference_0000032"} ! musculature of trunk [Term] id: UBERON:0003899 name: skeletal muscle of head def: "A skeletal muscle of the head." [OBOL:automatic] comment: defined generically so could in theory encompass FBbt:00003260 'skeletal muscle of head' synonym: "adult head skeletal muscle" EXACT [OBOL:automatic] synonym: "adult head skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "head skeletal muscle" EXACT [OBOL:automatic] synonym: "head skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of adult head" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of adult head" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of head" EXACT [OBOL:automatic] intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0000033 ! head xref: SCTID:244718003 ! Entire skeletal muscle of head relationship: part_of UBERON:0004461 {source="reference_0000032"} ! musculature of head [Term] id: UBERON:0008777 name: hypaxial musclulature def: "trunk muscles that lie ventral to the horizontal septum of the vertebrae." [Wikipedia:Epaxial_and_Hypaxial_muscles] synonym: "hypaxial muscle" RELATED [XAO:0003228] xref: XAO:0003228 ! hypaxial muscle xref: AAO:0000228 ! hypaxial muscles relationship: part_of UBERON:0001774 {source="XAO"} ! muscle of trunk intersection_of: UBERON:0001015 ! musculature intersection_of: develops_from UBERON:0003895 ! hypaxial myotome region property_value: external_definition "Trunk muscle that lies ventral to the horizontal septum of the vertebrae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000228", date_retrieved="2012-06-20", source="UBERON:0008777"} [Term] id: UBERON:0008778 name: epaxial musclulature def: "." [Wikipedia:Epaxial_and_Hypaxial_muscles] synonym: "epaxial muscle" EXACT [XAO:0003229] xref: AAO:0000142 ! epaxial_muscles xref: XAO:0003229 ! epaxial muscle relationship: part_of UBERON:0001774 {source="XAO"} ! muscle of trunk intersection_of: UBERON:0001015 ! musculature intersection_of: develops_from UBERON:0003900 ! epaxial myotome region property_value: external_definition "Trunk muscles that lies dorsal to the horizontal septum.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000142", date_retrieved="2012-06-20", source="XAO:curator"} [Term] id: UBERON:0003895 name: hypaxial myotome region def: "Portion of myotome that is ventral to the horizontal septum" [ISBN10:0073040584] synonym: "hypaxial myotome region" EXACT [ZFA:0001085] synonym: "body wall muscle" RELATED [XAO:0003228] xref: ZFA:0001085 ! hypaxial myotome region is_a: UBERON:0001134 ! skeletal muscle tissue relationship: part_of UBERON:0003082 ! myotome xref: TAO:0001085 ! hypaxial myotome region [Term] id: UBERON:0003900 name: epaxial myotome region def: "Portion of myotome that is dorsal to the horizontal septum" [ISBN10:0073040584] synonym: "epaxial myotome regions" EXACT PLURAL [ZFA:0001084] is_a: UBERON:0001134 ! skeletal muscle tissue relationship: part_of UBERON:0003082 ! myotome xref: ZFA:0001084 ! epaxial myotome region xref: TAO:0001084 ! epaxial myotome region [Term] id: UBERON:0003901 name: horizontal septum def: "A logitudinal sheet of continuous connective tissue partition developing at the apex of the chevron-shaped myotome and separating dorsal (epaxial) and ventral (hypaxial) body wall muscle masses; each is destined to become, respectively, the epaxial and hyopaxial musculature." [ZFA:0000671, ISBN10:0073040584] synonym: "horizontal myoseptum" EXACT [ZFA:0000671] xref: ZFA:0000671 ! horizontal myoseptum xref: EFO:0003555 ! horizontal myoseptum is_a: UBERON:0003037 ! septum relationship: adjacent_to UBERON:0003900 ! epaxial muscle relationship: adjacent_to UBERON:0003895 ! hypaxial muscle relationship: only_in_taxon NCBITaxon:7776 {source="ISBN10:0073040584"} ! Gnathostomata xref: TAO:0000671 ! horizontal myoseptum property_value: external_definition "A connective tissue partition developing at the apex of the chevron-shaped myotome and separating dorsal (epaxial) and ventral (hypaxial) body wall muscle masses. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000671", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass myoseptum (TAO:0001089)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000671", date_retrieved="2012-08-14"} [Term] id: UBERON:0003906 name: cardiac jelly def: "Portion of extracellular matrix between the myocardium and the endocardium. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates." [ZFA:0001318] subset: vertebrate_core xref: ZFA:0001318 ! cardiac jelly xref: EHDAA:1271 ! cardiac jelly xref: EHDAA:1279 ! cardiac jelly xref: EHDAA:1922 ! cardiac jelly xref: EHDAA:1930 ! cardiac jelly xref: EHDAA:426 ! cardiac jelly xref: EHDAA:442 ! cardiac jelly xref: EHDAA:450 ! cardiac jelly xref: EHDAA:458 ! cardiac jelly xref: EHDAA:466 ! cardiac jelly xref: EHDAA:474 ! cardiac jelly xref: EHDAA:772 ! cardiac jelly xref: EHDAA:780 ! cardiac jelly xref: EHDAA:788 ! cardiac jelly xref: EHDAA:800 ! cardiac jelly xref: EHDAA:808 ! cardiac jelly xref: ncithesaurus:Cardiac_Jelly ! Cardiac Jelly xref: VHOG:0000936 ! heart cardiac jelly xref: RETIRED_EHDAA2:0000212 ! cardiac jelly is_a: UBERON:0000479 ! portion of tissue relationship: adjacent_to UBERON:0002349 ! myocardium relationship: adjacent_to UBERON:0002165 ! endocardium xref: XAO:0004120 ! cardiac jelly xref: TAO:0001318 ! cardiac jelly property_value: external_definition "The extracellular matrix between the myocardium and the endocardium. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001318", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "heart cardiac jelly" EXACT [VHOG:0000936] xref: UMLS:C1516293 [Term] id: UBERON:0003927 name: obsolete macula lagena def: "This term was obsoleted as it was previously defined midleadingly as 'A macula that is part of a cochlea'." [UBERON:cjm] is_obsolete: true consider: ZFA:0000116 [Term] id: UBERON:0003928 name: digestive system duct def: "A duct that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "duct of digestive system" EXACT [OBOL:automatic] synonym: "duct of gastrointestinal system" EXACT [OBOL:automatic] synonym: "gastrointestinal system duct" EXACT [OBOL:automatic] xref: ZFA:0005162 intersection_of: UBERON:0000058 intersection_of: part_of UBERON:0001007 xref: TAO:0005162 ! digestive system duct [Term] id: UBERON:0003929 name: gut epithelium def: "An epithelium that is part of a digestive tract [Automatically generated definition]." [OBOL:automatic] synonym: "digestive tract epithelial tissue" EXACT [OBOL:automatic] synonym: "digestive tract epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of digestive tract" EXACT [OBOL:automatic] synonym: "epithelial tissue of gut" EXACT [OBOL:automatic] synonym: "epithelial tissue of lower gastrointestinal tract" EXACT [OBOL:automatic] synonym: "epithelium of digestive tract" EXACT [OBOL:automatic] synonym: "epithelium of gut" EXACT [OBOL:automatic] synonym: "epithelium of lower gastrointestinal tract" EXACT [OBOL:automatic] synonym: "gut epithelial tissue" EXACT [OBOL:automatic] synonym: "lower gastrointestinal tract epithelial tissue" EXACT [OBOL:automatic] synonym: "lower gastrointestinal tract epithelium" EXACT [OBOL:automatic] xref: ZFA:0005123 xref: XAO:0003200 ! gut epithelium xref: BTO:0000956 ! gut epithelium xref: ncithesaurus:Gut_Epithelium ! Gut Epithelium xref: EHDAA2:0004567 ! gut epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001555 ! UBERON:0001555 ! digestive tract xref: TAO:0005123 ! gut epithelium property_value: external_definition "Epithelium lining the lumen of the gut.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005123", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0836205 [Term] id: UBERON:0003931 name: diencephalic white matter def: "White matter that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "diencephalic tract/commissure" EXACT [ZFA:0000338] synonym: "white matter of diencephalon" EXACT [FMA:83931] xref: ZFA:0000338 ! diencephalic white matter xref: FMA:83931 ! white matter of diencephalon intersection_of: UBERON:0002316 intersection_of: part_of UBERON:0001894 xref: TAO:0000338 ! diencephalic tracts and commissures synonym: "diencephalic tracts and commissures" EXACT [TAO:0000338] [Term] id: UBERON:0003933 name: cranial cartilage def: "A cartilage element that is part of the cranial skeleton." [UBERON:cjm, ZFA:0001458] synonym: "cartilage of cranium" EXACT [OBOL:automatic] synonym: "cranium cartilage" EXACT [OBOL:automatic] intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0010323 ! cranial skeletal system xref: TAO:0001458 ! cranial cartilage xref: ZFA:0001458 ! cranial cartilage property_value: external_definition "Cartilage which is part of the cranium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001458", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0003934 name: mesenchyme pectoral fin def: "Mesenchyme that is part of a pectoral fin [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme of pectoral fin" EXACT [OBOL:automatic] synonym: "pectoral fin mesenchyme" EXACT [OBOL:automatic] xref: ZFA:0001000 xref: EFO:0003604 ! mesenchyme pectoral fin intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0000151 xref: TAO:0001000 ! mesenchyme pectoral fin property_value: external_definition "Mesenchyme that is part of the pectoral fin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001000", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0003935 name: mesenchyme pelvic fin def: "Mesenchyme that is part of a pelvic fin [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme of pelvic fin" EXACT [OBOL:automatic] synonym: "pelvic fin mesenchyme" EXACT [OBOL:automatic] xref: ZFA:0001449 intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0000152 xref: TAO:0001449 ! mesenchyme pelvic fin [Term] id: UBERON:0003936 name: postoptic commissure synonym: "POC" EXACT [ZFA:0000059] synonym: "post optic commissure" EXACT [ZFA:0000059] synonym: "post-optic commissure" EXACT [ZFA:0000059] xref: ZFA:0000059 ! postoptic commissure xref: EFO:0003478 ! postoptic commissure is_a: UBERON:0001020 ! commissure relationship: part_of UBERON:0003931 ! diencephalic white matter xref: TAO:0000059 ! postoptic commissure [Term] id: UBERON:0003938 name: sensory dissociation area def: "the area of the parietal lobe that integrates tactile and visual stimuli" [MP:0000796] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001872 ! parietal lobe [Term] id: UBERON:0003942 name: somatic sensory system def: "the neural tissue involved in the transmission of sensory signals" [MP:0000959] comment: TODO - check intersection_of: UBERON:0001032 ! sense organ system intersection_of: part_of UBERON:0000012 ! somatic nervous system [Term] id: UBERON:0003945 name: somatic motor system def: "the neural tissue involved in the transmission of motor signals" [MP:0001051] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000012 ! somatic nervous system [Term] id: UBERON:0003946 name: placenta labyrinth def: "the placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [MP:0001716] comment: Taxon notes: Mouse-human differences: The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively ... The mouse placental labyrinth is composed of an intricate network of maternal blood spaces and embryonal blood vessels. Maternal and embryonal blood is separated by a placental barrier that consists of four cellular layers: layer I trophoblasts line the maternal lacunae, trophoblasts in layers II and III form syncytial-like layers, and endothelial cells line the embryonic vessels[doi: 10.1073/pnas.96.14.8138 ]. See also: http://placentation.ucsd.edu/placenta.html synonym: "labyrinthine layer" EXACT [GO:0060713] synonym: "labyrinthine layer of placenta" EXACT [GO:0060713] synonym: "placental labyrinth" EXACT [] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001987 ! placenta relationship: never_in_taxon NCBITaxon:9606 {source="http://placentation.ucsd.edu"} ! Homo sapiens [Term] id: UBERON:0003948 name: blood-air barrier def: "the membrane between the capillary blood and alveolar air, comprised of the alveolar epithelium and the capillary epithelium and their adherent basement membranes and epithelial cell cytoplasm" [MP:0002324] comment: TODO - alveolar lumen xref: MESH:A04.411.715.025 ! blood-air barrier is_a: UBERON:0000119 ! cell layer relationship: adjacent_to UBERON:0000178 ! blood relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0003950 name: inner ear canal def: "the tubular ducts of the inner ear" [MP:0002729] is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0001846 ! internal ear [Term] id: UBERON:0003951 name: ocular fundus def: "the posterior concave interior of the eye, consisting of the retina, the choroid, the posterior segment of the sclera, the optic disk, and blood vessels, visible by an ophthalmoscope" [MP:0002864, Wikipedia:Fundus_(eye)] comment: TODO - check relationships synonym: "fundus" EXACT [HP:0001098] synonym: "fundus of eye" EXACT [] synonym: "eye fundus" EXACT [] synonym: "fundus oculi" EXACT [] xref: GAID:908 ! fundus oculi xref: galen:FundusOculi ! fundus oculi xref: ncithesaurus:Fundus ! Fundus xref: RETIRED_EHDAA2:0000583 ! fundus xref: MESH:A09.371.729.313 ! fundus oculi is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001802 ! posterior segment of eyeball xref: SCTID:362519003 ! Entire fundus of eye xref: UMLS:C0740422 [Term] id: UBERON:0003952 name: anterior stroma def: "the anterior segment of the lamellated connective tissue layer of the cornea" [MP:0003093] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001777 ! substantia propria of cornea [Term] id: UBERON:0003953 name: posterior stroma def: "the posterior segment of the lamellated connective tissue layer of the cornea" [MP:0003094] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001777 ! substantia propria of cornea [Term] id: UBERON:0010157 name: sphenoparietal suture def: "The Sphenoparietal suture is the cranial suture between the sphenoid bone and the parietal bone." [Wikipedia:Sphenoparietal_suture] synonym: "spheno-parietal suture" EXACT [] synonym: "sphenoparietal suture of skull" EXACT [FMA:52945] intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0000210 ! tetrapod parietal bone intersection_of: connects UBERON:0001677 ! sphenoid bone xref: FMA:52945 ! sphenoparietal suture xref: SCTID:136551005 ! Entire sphenoparietal suture of skull synonym: "Sutura sphenoparietalis" RELATED LATIN [Wikipedia:Sphenoparietal_suture] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray164.png [Term] id: UBERON:0003954 name: squamoparietal suture def: "the articulation of the squamous portion of the temporal bones with the parietal bones[MP]. The squamosal suture arches backward from the pterion and connects the temporal squama with the lower border of the parietal: this suture is continuous behind with the short, nearly horizontal parietomastoid suture, which unites the mastoid process of the temporal with the region of the mastoid angle of the parietal[WP]." [Wikipedia:Squamosal_suture, MP:0003844] synonym: "sutura squamosa cranii" EXACT LATIN [Wikipedia:Squamosal_suture] synonym: "squamosal suture" RELATED [Wikipedia:Squamosal_suture] synonym: "squamous suture" RELATED [Wikipedia:Squamosal_suture] synonym: "squamo-parietal suture" EXACT [MP:0003844] synonym: "squamoparietal suture of skull" EXACT [] synonym: "squamous suture of skull" RELATED [FMA:52946] xref: EMAPA:19228 ! squamo-parietal suture xref: FMA:52946 ! squamous suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0001695 ! squamous part of temporal bone intersection_of: connects UBERON:0000210 ! tetrapod parietal bone relationship: continuous_with UBERON:0010155 ! parietomastoid suture xref: http://upload.wikimedia.org/wikipedia/commons/a/a8/Gray188-Squamosal_suture.png xref: SCTID:136248004 ! Entire squamous suture of skull xref: SCTID:334174000 ! Entire squamous suture [Term] id: UBERON:0010155 name: parietomastoid suture def: "unites the mastoid process of the temporal with the region of the mastoid angle of the parietal[WP:Squamosal_suture]." [] synonym: "parietomastoid suture of skull" EXACT [FMA:52947] synonym: "parieto-mastoid suture of skull" EXACT [] is_a: UBERON:0003685 {source="FMA"} ! cranial suture relationship: connects UBERON:0000210 ! tetrapod parietal bone relationship: connects UBERON:0001678 ! temporal bone xref: FMA:52947 ! parietomastoid suture xref: SCTID:136753005 ! Entire parietomastoid suture of skull [Term] id: UBERON:0010156 name: sphenofrontal suture def: "The Sphenofrontal suture is the cranial suture between the sphenoid bone and the frontal bone." [Wikipedia:Sphenofrontal_suture] synonym: "sphenofrontal" RELATED [Wikipedia:Sphenofrontal_suture] synonym: "spheno-frontal suture" RELATED [] synonym: "sutura sphenofrontalis" RELATED [Wikipedia:Sphenofrontal_suture] synonym: "frontosphenoid suture" EXACT [FMA:52938] synonym: "sphenofrontal suture of skull" EXACT [FMA:52938] intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0001677 ! sphenoid bone intersection_of: connects UBERON:0000209 ! tetrapod frontal bone xref: FMA:52938 ! sphenofrontal suture xref: SCTID:136349005 ! Entire sphenofrontal suture of skull synonym: "Sutura sphenofrontalis" RELATED LATIN [Wikipedia:Sphenofrontal_suture] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray164.png [Term] id: UBERON:0010158 name: sphenozygomatic suture def: "The Sphenozygomatic suture is the cranial suture between the sphenoid bone and the zygomatic bone." [Wikipedia:Sphenozygomatic_suture] synonym: "sphenozygomatica suture of skull" EXACT [FMA:52956] intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0001677 ! sphenoid bone intersection_of: connects UBERON:0001683 ! zygomatic bone xref: FMA:52956 ! sphenozygomatic suture xref: SCTID:368980007 ! Entire sphenozygomatic suture of skull synonym: "sutura sphenozygomatica" RELATED LATIN [Wikipedia:Sphenozygomatic_suture] xref: http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray189.png [Term] id: UBERON:0010159 name: occipitomastoid suture def: "The occipitomastoid suture is the cranial suture between the occipital bone and the mastoid portion of the temporal bone. It is continuous with the lambdoidal suture." [Wikipedia:Occipitomastoid_suture] synonym: "occipito-mastoid suture" RELATED [Wikipedia:Occipitomastoid_suture] synonym: "sutura occipitomastoidea" RELATED [Wikipedia:Occipitomastoid_suture] synonym: "occipitomastoid suture of skull" EXACT [FMA:52934] is_a: UBERON:0003685 {source="FMA"} ! cranial suture relationship: connects UBERON:0001676 ! occipital bone relationship: connects UBERON:0001678 ! temporal bone xref: FMA:52934 ! occipitomastoid suture xref: SCTID:134136005 ! Entire occipitomastoid suture of skull synonym: "sutura occipitomastoidea" RELATED LATIN [Wikipedia:Occipitomastoid_suture] xref: http://upload.wikimedia.org/wikipedia/commons/d/df/Occipitomastoideus.PNG [Term] id: UBERON:0011871 name: nasomaxillary suture synonym: "nasomaxillary suture of skull" EXACT [FMA:52960] synonym: "articulation of the nasal bone with maxilla" RELATED [] intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0001681 ! nasal bone intersection_of: connects UBERON:0002397 ! maxilla xref: FMA:52960 ! nasomaxillary suture def: "A cranial suture that connects a nasal bone and connects a maxilla." [OBOL:automatic] [Term] id: UBERON:0003955 name: molar crown def: "the part of a molar that is covered by enamel" [MP:0003932] synonym: "molar tooth tooth crown" EXACT [OBOL:automatic] synonym: "tooth crown of molar tooth" EXACT [OBOL:automatic] synonym: "crown of molar tooth" EXACT [FMA:85301] synonym: "molar tooth crown" EXACT [FMA:85301] xref: FMA:85301 ! Crown of molar tooth intersection_of: UBERON:0003675 ! tooth crown intersection_of: part_of UBERON:0003655 ! molar tooth! relationship: part_of UBERON:0003655 ! molar tooth [Term] id: UBERON:0003956 name: aqueous drainage system def: "the structures associated with drainage of the aqueous humor from the eye, that include the trabecular meshwork, Schlemm's canal, the uveoscleral network, and the aqueous veins" [MP:0005198] is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0001768 ! uvea [Term] id: UBERON:0005630 ! fetal membrane name: fetal membrane def: "the amnion and chorion which surround and protect a developing fetus." [Wikipedia:Fetal_membrane] synonym: "adnexa fetalia" RELATED LATIN [] comment: todo - merge with extraembryonic membrane? xref: BTO:0000473 ! fetal membrane xref: MESH:A16.254.403 ! fetal membrane is_a: UBERON:0005631 ! extraembryonic membrane xref: SCTID:325510007 ! Fetal membranes [Term] id: UBERON:0005631 ! extraembryonic membrane name: extraembryonic membrane def: "Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo." [ISBN10:0073040584 "Vertebrates\, Kardong"] comment: AO notes: EHDAA2 is a mereological sum. Taxon notes: stuctures homologous to the four extraembryonic membranes appear in mammals [ISBN10:0073040584 "Vertebrates\, Kardong"] is_a: UBERON:0000478 ! extraembryonic structure is_a: UBERON:0000158 ! membranous layer relationship: only_in_taxon NCBITaxon:32524 ! Amniota xref: SCTID:362840007 ! extraembryonic membranes xref: EHDAA2:0004714 ! embryonic membranes property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000010" xsd:anyURI [Term] id: UBERON:0005335 name: chorioallantoic membrane def: "The chorioallantoic membrane is a vascular membrane found in eggs of some amniotes, such as birds and reptiles. It is formed by the fusion of the mesodermal layers of two developmental structures: the allantois and the chorion. Three different layers compose the chorioallantoic membrane; these are called the chorionic epithelium, the mesenchyme and the allantoic epithelium. Blood capillaries and sinuses are found between epithelial cells of the chorionic layer, allowing close contact (within 0.2 N' shaped notch. The maxillary process forms the lateral wall and floor of the orbit, and in it are ossified the zygomatic bone and the greater part of the maxilla; it meets with the lateral nasal process, from which, however, it is separated for a time by a groove, the naso-optic furrow, that extends from the furrow encircling the eyeball to the olfactory pit. The maxillary processes ultimately fuse with the lateral nasal and globular processes, and form the lateral parts of the upper lip and the posterior boundaries of the nares. It is innervated by the maxillary nerve." [Wikipedia:Maxillary_prominence] synonym: "maxillary process" EXACT [EHDAA2:0001070] xref: EHDAA2:0001070 ! maxillary process xref: EMAPA:17359 ! maxillary process xref: EHDAA:5877 ! maxillary process is_a: UBERON:0005423 ! developing anatomical structure disjoint_from: UBERON:0005869 ! maxillary process of inferior nasal concha relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0007238 ! 1st arch maxillary component xref: ncithesaurus:Maxillary_Prominence ! Maxillary Prominence xref: SCTID:346355001 ! maxillary process of embryo synonym: "maxillary process of embryo" EXACT [] synonym: "embryonic maxillary process" EXACT [] synonym: "prominentia maxilaris" RELATED LATIN [Wikipedia:Maxillary_prominence] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray48.png xref: UMLS:C1513037 [Term] id: UBERON:0004071 name: cerebellum emboliform nucleus def: "the small wedge shaped nucleus interposed between the dentate and fastigial nuclei; it receives axons from Purkinje cells of the intermediate area of the cerebral hemispheres and most of its efferent connections travel via the superior cerebellar peduncle" [MP:0009981] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002037 ! cerebellum xref: SCTID:279222003 ! Entire cerebellar emboliform nucleus [Term] id: UBERON:0004072 name: cerebellum globose nucleus def: "the two or three small masses of gray matter that is located medial to the emboliform nucleus and lateral to the fastigial nucleus; it receives axons from the intermediate area of the cerebellar hemispheres and its afferents exit through the superior cerebellar peduncle; it is recognized in human cerebellum but is not distinguishable in all mammalian species" [MP:0009982] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002037 ! cerebellum xref: SCTID:279223008 ! Entire cerebellar globose nucleus [Term] id: UBERON:0004073 name: cerebellum interpositus nucleus def: "the nucelus composed of the globose and emoliform nuclei of the cerebellum; in some mammalian species the globose nucleus is not distinguishable" [MP:0009984] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002037 ! cerebellum [Term] id: UBERON:0005293 ! cerebellum lobe name: cerebellum lobe synonym: "lobe of cerebellum" EXACT [FMA:242392] synonym: "cerebellar lobe" EXACT [FMA:242392] synonym: "lobe parts of the cerebellar cortex" EXACT [NIF_GrossAnatomy:birnlex_1076] xref: MA:0002963 ! cerebellum lobe xref: FMA:242392 ! Lobe of cerebellum xref: NIF_GrossAnatomy:birnlex_1076 ! Lobe parts of the cerebellar cortex is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002129 ! cerebellar cortex xref: SCTID:263971006 ! Entire cerebellar lobe [Term] id: UBERON:0003012 name: flocculonodular lobe def: "The flocculonodular lobe is a lobe of the cerebellum consisting of the nodule and the flocculus. It is closely associated with the vestibulocerebellum. [WP,unvetted]." [Wikipedia:Flocculonodular_lobe] subset: uberon_slim synonym: "flocculonodular lobe" EXACT [FMA:72253] synonym: "posterior lobe-2 of cerebellum" EXACT [FMA:72253] synonym: "cerebellum flocculonodular lobe" EXACT [MA:0002965] synonym: "flocculonodular lobe of cerebellum" EXACT [FMA:72253] xref: FMA:72253 ! Flocculonodular lobe of cerebellum xref: NIF_GrossAnatomy:birnlex_904 ! Flocculonodular lobe xref: MA:0002965 ! cerebellum flocculonodular lobe xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/43/CerebellumDiv.png/200px-CerebellumDiv.png xref: EV:0100297 ! flocculonodular lobe is_a: UBERON:0005293 ! cerebellum lobe synonym: "lobus flocculonodularis" EXACT LATIN [FMA:TA, FMA:72253] xref: SCTID:279361008 ! Entire flocculonodular lobe xref: http://upload.wikimedia.org/wikipedia/commons/4/43/CerebellumDiv.png [Term] id: UBERON:0004002 ! cerebellum posterior lobe name: cerebellum posterior lobe def: "the region of the cerebellum that is posterior to the primary fissure and anterior to the posteriolateral fissure" [MP:0009962] synonym: "posterior lobe of cerebellum" EXACT [] synonym: "cerebrocerebellum" EXACT [FMA:72252] synonym: "middle lobe-1 of cerebellum" EXACT [FMA:72252] synonym: "posterior cerebellar lobe" EXACT [FMA:72252] synonym: "posterior lobe-1 of cerebellum" EXACT [FMA:72252] synonym: "posterior lobe of the cerebellum" EXACT [NIF_GrossAnatomy:birnlex_911] xref: FMA:72252 ! Posterior lobe of cerebellum xref: MA:0002964 ! cerebellum posterior lobe xref: NIF_GrossAnatomy:birnlex_911 ! posterior lobe of the cerebellum is_a: UBERON:0005293 ! cerebellum lobe xref: SCTID:279360009 ! Entire posterior cerebellar lobe [Term] id: UBERON:0002131 ! anterior lobe of cerebellum name: anterior lobe of cerebellum def: "The anterior lobe of cerebellum is the portion of the cerebellum responsible for mediating unconscious proprioception. In alcoholics, it can deteriorate. It is sometimes equated to the 'paleocerebellum'. [WP,unvetted]." [Wikipedia:Anterior_lobe_of_cerebellum] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "anterior lobe of cerebellum" EXACT [] synonym: "anterior cerebellar lobe" EXACT [] synonym: "cerebellum anterior lobe" EXACT [] synonym: "anterior lobe of the cerebellum" EXACT [NIF_GrossAnatomy:birnlex_1118] xref: FMA:72251 ! Anterior lobe of cerebellum xref: MA:0000991 ! cerebellum anterior lobe xref: NIF_GrossAnatomy:birnlex_1118 ! Anterior lobe of the cerebellum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/13/CerebellumRegions.jpg/200px-CerebellumRegions.jpg xref: EV:0100295 ! anterior lobe of the cerebellum is_a: UBERON:0005293 ! cerebellum lobe relationship: has_function_in GO:0019230 {source="Wikipedia"} ! proprioception xref: SCTID:279359004 ! Entire anterior cerebellar lobe xref: http://upload.wikimedia.org/wikipedia/commons/1/13/CerebellumRegions.jpg xref: VHOG:0001598 ! cerebellum anterior lobe [Term] id: UBERON:0004720 ! cerebellar vermis name: cerebellar vermis def: "Part of the structure of animal brains, the cerebellar vermis is a narrow, wormlike structure between the hemispheres of the cerebellum." [Wikipedia:Cerebellar_vermis] synonym: "vermis" RELATED [Wikipedia:Cerebellar_vermis] synonym: "vermis of cerebellum" EXACT [FMA:76928] synonym: "cerebellum vermis" EXACT [FMA:76928] synonym: "vermis of cerebellum [i-x]" EXACT [FMA:76928] synonym: "vermal parts of the cerebellum" EXACT [NIF_GrossAnatomy:birnlex_1175] synonym: "vermal regions" EXACT [ABA:VERM] xref: MA:0000202 ! cerebellar vermis xref: FMA:76928 ! Vermis of cerebellum xref: NIF_GrossAnatomy:birnlex_1175 ! Vermal parts of the cerebellum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/43/CerebellumDiv.png/200px-CerebellumDiv.png xref: EV:0100298 ! vermis xref: ABA:VERM ! Vermal regions is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002129 {source="ABA"} ! cerebellar cortex relationship: part_of UBERON:0002037 ! cerebellum synonym: "vermis cerebelli [i-x]" EXACT LATIN [FMA:TA, FMA:76928] xref: ncithesaurus:Vermis ! Vermis xref: SCTID:279105006 ! Entire cerebellar vermis synonym: "vermis cerebelli" RELATED LATIN [Wikipedia:Cerebellar_vermis] xref: http://upload.wikimedia.org/wikipedia/commons/4/43/CerebellumDiv.png xref: UMLS:C0228482 [Term] id: UBERON:0003941 name: cerebellum anterior vermis def: "the anterior portion of the narrow middle zone between the two hemispheres of the cerebellum that is located anterior to the primary fissure" [MP:0000867] synonym: "vermis of anterior lobe of cerebellum" EXACT [FMA:72255] synonym: "anterior cerebellum vermis" EXACT [MA:0002969] synonym: "anterior vermis of cerebellum" EXACT [FMA:72255] synonym: "part of vermal region" EXACT [FMA:72255] synonym: "vermis of anterior lobe" EXACT [FMA:72255] xref: FMA:72255 ! Vermis of anterior lobe of cerebellum xref: MA:0002969 ! anterior cerebellum vermis xref: NIF_GrossAnatomy:birnlex_1185 ! Vermis of the anterior lobe of the cerebellum is_a: UBERON:0004720 ! cerebellar vermis relationship: part_of UBERON:0002131 ! anterior lobe of cerebellum [Term] id: UBERON:0004009 name: cerebellum posterior vermis def: "the posterior portion of the narrow middle zone between the two hemispheres of the cerebellum that is located posterior to the primary fissure" [MP:0000869] synonym: "vermis of posterior lobe of cerebellum" EXACT [] synonym: "posterior cerebellum vermis" EXACT [] synonym: "vermis of posterior lobe" EXACT [FMA:72259] synonym: "vermis of the posterior lobe of the cerebellum" EXACT [NIF_GrossAnatomy:nlx_anat_20081240] xref: NIF_GrossAnatomy:nlx_anat_20081240 ! Vermis of the posterior lobe of the cerebellum xref: MA:0002970 ! posterior cerebellum vermis xref: FMA:72259 ! Vermis of posterior lobe of cerebellum is_a: UBERON:0004720 ! cerebellar vermis relationship: part_of UBERON:0004002 ! cerebellum posterior lobe [Term] id: UBERON:0004004 ! cerebellum lobule name: cerebellum lobule def: "one of the the ten gyri of the cerebellar cortex" [MP:0009964] synonym: "lobular parts of the cerebellar cortex" EXACT [NIF_GrossAnatomy:birnlex_1084] xref: MA:0002966 ! cerebellum lobule xref: NIF_GrossAnatomy:birnlex_1084 ! Lobular parts of the cerebellar cortex is_a: UBERON:0002946 ! regional part of cerebellum relationship: part_of UBERON:0002129 ! cerebellar cortex [Term] id: UBERON:0004003 name: cerebellum hemisphere lobule def: "the region of a cerebellar lobule that resides in either of the lateral sections of the cerebellum outside the vermis; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres" [MP:0009963] comment: TODO - define as a region overlapping synonym: "cerebellar hemisphere lobule" EXACT [] synonym: "lobule of hemisphere of cerebellum" EXACT [FMA:83880] synonym: "lobule of cerebellar hemisphere" EXACT [FMA:83880] xref: FMA:83880 ! Lobule of hemisphere of cerebellum xref: MA:0002967 ! cerebellum hemisphere lobule intersection_of: UBERON:0004004 ! cerebellum lobule intersection_of: part_of UBERON:0002245 ! hemisphere of cerebellum [Term] id: UBERON:0003021 ! central lobule name: central lobule def: "The central lobule is a small square lobule, situated in the anterior cerebellar notch. It overlaps the lingula, from which it is separated by the precentral fissure; laterally, it extends along the upper and anterior part of each hemisphere, where it forms a wing-like prolongation, the ala lobuli centralis. [WP,unvetted]." [Wikipedia:Central_lobule] subset: uberon_slim synonym: "central lobule of cerebellum" EXACT [FMA:72519] synonym: "central lobule of cerebellum [II and III]" EXACT [FMA:72519] xref: FMA:72519 ! central lobule [SYNONYM: "central lobule of cerebellum" (exact)] [SYNONYM: "central lobule of cerebellum [ii and iii]" (exact)] [regional_part_of: "vermis of anterior lobe of cerebellum"] [subclass: "lobule of hemisphere of cerebellum"] xref: NIF_GrossAnatomy:birnlex_920 ! Central lobule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Gray703.png/200px-Gray703.png xref: ABA:CENT ! Central lobule is_a: UBERON:0004003 ! cerebellum hemisphere lobule relationship: spatially_disjoint_from UBERON:0004077 {source="ABA"} ! cerebellum vermis lobule IV synonym: "lobulus centralis cerebelli [ii et iii]" EXACT LATIN [FMA:TA, FMA:72519] xref: SCTID:279383007 ! Entire central lobule of cerebellum synonym: "lobulus centralis" RELATED LATIN [Wikipedia:Central_lobule] xref: http://upload.wikimedia.org/wikipedia/commons/e/e4/Gray703.png [Term] id: UBERON:0004070 name: cerebellum vermis lobule def: "the region of a cerebellar lobule that resides in the central section of the cerebellum between the two hemispheres; in humans, vermis lobule regions may be nearly continuous with the cerebellar hemisphere lobules dorsally but are separated by deeper longitudinal fissues in the ventral regions; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres" [MP:0009957] comment: TODO - define as a region overlapping xref: MA:0002968 ! cerebellum vermis lobule xref: NIF_GrossAnatomy:nlx_anat_20081223 ! Regional Parts of the Vermal Lobules intersection_of: UBERON:0004004 ! cerebellum lobule intersection_of: part_of UBERON:0004720 ! cerebellar vermis [Term] id: UBERON:0004074 name: cerebellum vermis lobule I def: "." [MP:0009988] comment: TODO FMA:61904 lingual gyrus FMA:71032 lingula gyrus (lg) synonym: "lingula" RELATED [MA:0000998] synonym: "neuraxis lingula" EXACT [] synonym: "lingula of cerebellum" EXACT [] synonym: "lobule I of cerebellum vermis" EXACT [] synonym: "lingula of anterior cerebellum vermis" EXACT [] synonym: "lingula (I)" EXACT [ABA:LING] xref: MA:0000998 ! cerebellum vermis lobule I [SYNONYM: "lingula" (related)] [part_of: "anterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: FMA:83884 ! lingula of cerebellum [SYNONYM: "neuraxis lingula" (exact)] [regional_part_of: "vermis of anterior lobe of cerebellum"] [subclass: "segment of cerebellum"] xref: NIF_GrossAnatomy:birnlex_932 ! Lingula [SYNONYM: "lingula" (exact)] [subclass: "Lobular parts of the cerebellar cortex"] xref: ABA:LING ! Lingula (I) is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0002037 ! cerebellum relationship: part_of UBERON:0003941 ! cerebellum anterior vermis xref: SCTID:77232000 ! Lingula of cerebellum [Term] id: UBERON:0004075 name: cerebellum vermis lobule II def: "." [MP:0009989] comment: central vs alar central? II and III? part_of CENT in ABA synonym: "vermic lobule II" EXACT [NIF_GrossAnatomy:nlx_anat_20081225] synonym: "central lobule" BROAD [MA:0000999] synonym: "central lobule of cerebellum" BROAD [] synonym: "lobule II of cerebellum vermis" EXACT [] synonym: "lobule II" EXACT [ABA:CENT2] xref: ABA:CENT2 ! Lobule II xref: MA:0000999 ! cerebellum vermis lobule II [SYNONYM: "central lobule" (related)] [part_of: "anterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: NIF_GrossAnatomy:nlx_anat_20081225 ! Vermic Lobule II is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0003941 {source="MA"} ! cerebellum anterior vermis relationship: part_of UBERON:0003021 {source="ABA"} ! central lobule [Term] id: UBERON:0004076 name: cerebellum vermis lobule III def: "." [MP:0009990] comment: II or III? synonym: "central lobule" BROAD [MA:0001000] synonym: "central lobule of cerebellum" BROAD [] synonym: "lobule III of cerebellum vermis" EXACT [] synonym: "lobule III" EXACT [ABA:CENT3] xref: MA:0001000 ! cerebellum vermis lobule III [SYNONYM: "central lobule" (related)] [part_of: "anterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: NIF_GrossAnatomy:nlx_anat_20081226 ! Vermic Lobule III xref: ABA:CENT3 ! Lobule III is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0002037 ! cerebellum relationship: part_of UBERON:0003941 ! cerebellum anterior vermis relationship: part_of UBERON:0003021 {source="ABA"} ! central lobule [Term] id: UBERON:0007763 ! cerebellum culmen name: cerebellum culmen comment: ABA splits culmen into IV and V and IV-V synonym: "neuraxis culmen" EXACT [FMA:83886] xref: FMA:83886 ! culmen of cerebellum xref: ABA:CUL ! Culmen xref: SCTID:279384001 ! Entire culmen xref: NIF_GrossAnatomy:birnlex_926 ! Culmen [SYNONYM: "culmen" (exact)] [subclass: "Lobular parts of the cerebellar cortex"] xref: SCTID:89649002 ! Structure of culmen synonym: "culmen" BROAD [MA:0001001, NIF_GrossAnatomy:birnlex_926] is_a: UBERON:0004070 {source="ABA"} ! cerebellum vermis lobule relationship: part_of UBERON:0003941 {source="FMA"} ! cerebellum anterior vermis [Term] id: UBERON:0004077 name: cerebellum vermis lobule IV def: "The culmen is the portion of the anterior vermis adjacent to the primary fissure of cerebellum. The culmen and the anterior parts of the quadrangular lobules form the lobus culminis[WP]." [MP:0009991, Wikipedia:Culmen_(cerebellum)] synonym: "culmen of cerebellum" BROAD [] synonym: "neuraxis culmen" BROAD [FMA:83886] synonym: "lobule IV of cerebellum vermis" EXACT [] xref: MA:0001001 ! cerebellum vermis lobule IV [SYNONYM: "culmen" (related)] [part_of: "anterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: NIF_GrossAnatomy:nlx_anat_20081227 ! Vermic Lobule IV xref: ABA:CUL4 ! Lobule IV is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0007763 {source="ABA"} ! cerebellum culmen relationship: spatially_disjoint_from UBERON:0003021 {source="ABA"} ! central lobule [Term] id: UBERON:0004079 name: cerebellum vermis lobule V def: "." [MP:0009993] synonym: "lobule V of cerebellum vermis" EXACT [] synonym: "culmen" BROAD [MA:0001002] synonym: "culmen of cerebellum" BROAD [] synonym: "neuraxis culmen" BROAD [FMA:83886] synonym: "lobule V" EXACT [ABA:CUL5] xref: MA:0001002 ! cerebellum vermis lobule V [SYNONYM: "culmen" (related)] [part_of: "anterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: NIF_GrossAnatomy:nlx_anat_20081228 ! Vermic Lobule V xref: ABA:CUL5 ! Lobule V is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0007763 {source="ABA"} ! cerebellum culmen [Term] id: UBERON:0004080 name: cerebellum vermis lobule VI alt_id: UBERON:0000909 alt_id: UBERON:Declive-MA_0001003 def: "." [MP:0009994] synonym: "lobule VI of cerebellum vermis" EXACT [] synonym: "declive" BROAD [MA:0001003] synonym: "neuraxis declive" EXACT [FMA:83887] synonym: "declive of cerebellum" EXACT [] synonym: "declive of vermis of cerebellum" EXACT [] synonym: "vermic lobule vi" EXACT [NIF_GrossAnatomy:nlx_anat_20081229] synonym: "declive (VI)" EXACT [ABA:DEC] xref: MA:0001003 ! cerebellum vermis lobule VI [SYNONYM: "declive" (related)] [part_of: "posterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: FMA:83887 ! declive of cerebellum [SYNONYM: "neuraxis declive" (exact)] [regional_part_of: "vermis of posterior lobe of cerebellum"] [regional_part_of: "simple lobule of cerebellum"] [subclass: "segment of cerebellum"] xref: NIF_GrossAnatomy:nlx_anat_20081229 ! Vermic Lobule VI xref: ABA:DEC ! Declive (VI) is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0002037 ! cerebellum relationship: part_of UBERON:0004009 ! cerebellum posterior vermis xref: SCTID:279385000 ! Entire cerebellar declive [Term] id: UBERON:0004081 ! cerebellum vermis lobule VII name: cerebellum vermis lobule VII def: "The folium vermis is a short, narrow, concealed band at the posterior extremity of the vermis, consisting apparently of a single folium, but in reality marked on its upper and under surfaces by secondary fissures. Laterally, it expands in either hemisphere into a considerable lobule, the superior semilunar lobule (lobulus semilunaris superior; postero-superior lobules), which occupies the posterior third of the upper surface of the hemisphere, and is bounded below by the horizontal sulcus. The superior semilunar lobules and the folium vermis form the lobus semilunaris." [MP:0009995, Wikipedia:Folium_(vermis)] comment: check MA, MP, FMA, folium? synonym: "vermic lobule VII" EXACT [NIF_GrossAnatomy:nlx_anat_20081230] synonym: "lobule VII of cerebellum vermis" EXACT [] synonym: "folium" BROAD [MA:0001004] synonym: "folium lobule" NARROW [MP:0009995] synonym: "neuraxis folium" EXACT [FMA:83889] synonym: "folium of cerebellum" EXACT [] synonym: "folium of vermis of cerebellum" EXACT [] synonym: "folium-tuber vermis (VII)" EXACT [ABA:FOTU] xref: MA:0001004 ! cerebellum vermis lobule VII [SYNONYM: "folium" (related)] [part_of: "posterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: FMA:83889 ! folium of vermis of cerebellum [SYNONYM: "neuraxis folium" (exact)] [regional_part_of: "vermis of posterior lobe of cerebellum"] [subclass: "segment of cerebellum"] xref: NIF_GrossAnatomy:nlx_anat_20081230 ! Vermic Lobule VII xref: ABA:FOTU ! Folium-tuber vermis (VII) is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0002037 ! cerebellum relationship: part_of UBERON:0004009 ! cerebellum posterior vermis xref: SCTID:369044003 ! Entire cerebellar folium [Term] id: UBERON:0005345 name: cerebellum vermis lobule VIIa def: "." [MP:0009998] synonym: "vermic lobule VIIA" EXACT [NIF_GrossAnatomy:nlx_anat_20081231] xref: NIF_GrossAnatomy:nlx_anat_20081231 ! Vermic Lobule VIIA is_a: UBERON:0004081 {source="NIF"} ! cerebellum vermis lobule VII [Term] id: UBERON:0005346 name: cerebellum vermis lobule VIIb def: "." [MP:0009999] is_a: UBERON:0004081 {source="NIF"} ! cerebellum vermis lobule VII [Term] id: UBERON:0004082 name: cerebellum vermis lobule VIII alt_id: UBERON:0002312 def: "." [MP:0009996] synonym: "pyramis" EXACT [NIF_GrossAnatomy:nlx_anat_20081233] synonym: "vermic lobule VIII" EXACT [NIF_GrossAnatomy:nlx_anat_20081233] synonym: "lobule VIII of cerebellum vermis" EXACT [] synonym: "pyramus" BROAD [MA:0001005] synonym: "neuraxis pyramus" EXACT [] synonym: "pyramus of cerebellum" EXACT [] synonym: "pyramus of vermis of cerebellum" EXACT [FMA:83888] synonym: "cerebellum lobule VIII" EXACT [] synonym: "neuraxis pyramis" EXACT [] synonym: "pyramus" RELATED [] synonym: "pyramis of vermis of cerebellum" EXACT [FMA:83888] synonym: "pyramus (VIII)" EXACT [ABA:PYR] xref: FMA:83888 ! Pyramis of vermis of cerebellum xref: MA:0001005 ! cerebellum vermis lobule VIII [SYNONYM: "pyramus" (related)] [part_of: "posterior cerebellum vermis"] [subclass: "cerebellum vermis lobule"] xref: NIF_GrossAnatomy:nlx_anat_20081233 ! Vermic Lobule VIII xref: ABA:PYR ! Pyramus (VIII) is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0002037 ! cerebellum relationship: part_of UBERON:0004009 ! cerebellum posterior vermis [Term] id: UBERON:0004078 name: cerebellum vermis lobule IX def: "." [MP:0009992] synonym: "uvula [vermis]" EXACT [] synonym: "neuraxis uvula" EXACT [FMA:83883] synonym: "uvula of cerebellum" EXACT [FMA:83883] synonym: "uvula of vermis of cerebellum" EXACT [] synonym: "lobule IX of cerebellar posterior vermis" EXACT [PMID:2022820] synonym: "cerebellar posterior vermis lobule IX" EXACT [PMID:2022820] synonym: "vermic lobule IX" EXACT [NIF_GrossAnatomy:nlx_anat_20081234] synonym: "lobule IX of cerebellum vermis" EXACT [] synonym: "uvula (IX)" EXACT [ABA:UVU] xref: MA:0001006 ! cerebellum vermis lobule IX xref: FMA:83883 ! uvula of vermis of cerebellum [SYNONYM: "neuraxis uvula" (exact)] [regional_part_of: "vermis of posterior lobe of cerebellum"] xref: NIF_GrossAnatomy:nlx_anat_20081234 ! Vermic Lobule IX xref: ABA:UVU ! Uvula (IX) is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0002037 ! cerebellum [Term] id: UBERON:0004083 name: cerebellum vermis lobule X def: "." [MP:0009997] synonym: "lobule X of cerebellum vermis" EXACT [] synonym: "nodulus" BROAD [MA:0001007] synonym: "neuraxis nodulus" EXACT [] synonym: "nodulus of cerebellum" EXACT [] synonym: "nodulus of vermis of cerebellum" EXACT [] synonym: "nodulus (X)" EXACT [ABA:NOD] xref: MA:0001007 ! cerebellum vermis lobule X [SYNONYM: "nodulus" (related)] [subclass: "cerebellum vermis lobule"] xref: FMA:83882 ! nodulus of cerebellum [SYNONYM: "neuraxis nodulus" (exact)] [regional_part_of: "flocculonodular lobe of cerebellum"] [regional_part_of: "vermis of posterior lobe of cerebellum"] [subclass: "segment of cerebellum"] xref: NIF_GrossAnatomy:birnlex_1165 ! Nodulus [SYNONYM: "nodulus" (exact)] [subclass: "Regional part of a lobe of the cerebellum"] xref: ABA:NOD ! Nodulus (X) is_a: UBERON:0004070 {source="MA"} ! cerebellum vermis lobule relationship: part_of UBERON:0002037 ! cerebellum [Term] id: UBERON:0002311 name: obsolete nodulus of cerebellum is_obsolete: true replaced_by: UBERON:0004083 ! cerebellum vermis lobule X [Term] id: UBERON:0011810 name: collection of feathers synonym: "plumage" EXACT [] synonym: "feather coat" EXACT [] intersection_of: UBERON:0000477 ! anatomical cluster intersection_of: composed_primarily_of UBERON:0000022 ! feather def: "An anatomical cluster that composed_primarily_of a feather." [OBOL:automatic] [Term] id: UBERON:0010164 name: collection of hairs synonym: "hairs" EXACT [FMA:70752] synonym: "hairs set" EXACT [FMA:70752] synonym: "pili" EXACT LATIN [FMA:TA] synonym: "set of hairs" EXACT [FMA:70752] xref: FMA:70752 ! set of hairs intersection_of: UBERON:0000477 ! anatomical cluster intersection_of: composed_primarily_of UBERON:0001037 ! strand of hair def: "An anatomical cluster that composed_primarily_of a strand of hair." [OBOL:automatic] [Term] id: UBERON:0010165 name: collection of hair on face synonym: "facial hairs set" EXACT [FMA:70741] synonym: "facial hair" RELATED [] synonym: "set of facial hairs" EXACT [FMA:70741] intersection_of: UBERON:0010164 ! collection of hairs intersection_of: part_of UBERON:0001456 ! face relationship: composed_primarily_of UBERON:0010171 ! hair of face subset: phenotype_rcn xref: FMA:70741 ! set of facial hairs def: "A collection of hairs that is part of a face." [OBOL:automatic] [Term] id: UBERON:0010171 ! strand of hair of face name: strand of hair of face synonym: "face hair strand" EXACT [] synonym: "face hair" EXACT [FMA:54360] synonym: "facial hair" RELATED [FMA:54360] synonym: "hair of face" EXACT [FMA:54360] intersection_of: UBERON:0001037 ! strand of hair intersection_of: part_of UBERON:0001456 ! face xref: FMA:54360 ! hair of face xref: SCTID:368910000 ! Entire hair of face def: "A strand of hair that is part of a face." [OBOL:automatic] [Term] id: UBERON:0010166 ! coat of hair name: coat of hair def: "." [Wikipedia:Coat_(animal)] synonym: "coat" BROAD [] synonym: "pelt" RELATED [] synonym: "coat pelt" RELATED [] synonym: "pelage" RELATED [] synonym: "fur coat" NARROW [] synonym: "wooly coat" NARROW [] synonym: "hair coat" EXACT [] synonym: "set of coat hairs" EXACT [] is_a: UBERON:0010164 ! collection of hairs subset: phenotype_rcn xref: ncithesaurus:Coat_Pelt ! coat [Term] id: UBERON:0010514 name: strand of duvet hair def: "A strand of hair from the fine underhair of the coat" [MP:0000408] comment: AO notes - not a pelage hair in MA, but is in MP is_a: UBERON:0001037 {source="MA"} ! strand of hair xref: MA:0001895 ! duvet hair synonym: "duvet hair" EXACT [MA:0001895] [Term] id: UBERON:0010509 name: strand of pelage hair intersection_of: UBERON:0001037 ! strand of hair intersection_of: part_of UBERON:0010166 ! coat of hair xref: MA:0001897 ! pelage hair synonym: "pelage hair" EXACT [MA:0001897] def: "A strand of hair that is part of a coat of hair." [OBOL:automatic] [Term] id: UBERON:0010510 name: strand of auchene hair def: "A truncal hair that has a single constriction and bend about midway along the hair shaft, and contains two or more air cells in the medulla" [MP:0000405] is_a: UBERON:0010509 {source="MA"} ! pelage hair xref: MA:0001893 ! auchene hair synonym: "auchene hair" EXACT [MA:0001893] [Term] id: UBERON:0010511 name: strand of awl hair def: "A truncal hairs that is straight, but shorter than a guard hair, and contain two or more air cells in the medulla" [MP:0000400, Wikipedia:Awn_hair] is_a: UBERON:0010509 {source="MA"} ! pelage hair xref: MA:0001894 ! awl hair synonym: "awl hair" EXACT [MA:0001894] [Term] id: UBERON:0010512 name: strand of guard hair def: "A long, straight truncal hair that contains two air cells in the medulla[MP]. A strand of hair from the top layer consisting of longer, often coarser, straight shafts of hair that stick out through the underfur. This is usually the visible layer for most mammals and contains most of the pigmentation. It protects the underfur from outside factors, such as rain, and is thus often water-repellent." [Wikipedia:Guard_hair, MP:0006365] is_a: UBERON:0010509 {source="MA"} ! pelage hair xref: MA:0001896 ! guard hair synonym: "guard hair" EXACT [MA:0001896] synonym: "guardhair" EXACT [] [Term] id: UBERON:0010513 name: strand of zigzag hair def: "A truncal hair that has two or more sharp bends with diameter constrictions at the bends, and contain one air cell in the medulla." [MP:0006366] is_a: UBERON:0010509 {source="MA"} ! pelage hair relationship: part_of UBERON:0002100 ! trunk xref: MA:0001898 ! zigzag hair synonym: "zigzag hair" EXACT [MA:0001898] [Term] id: UBERON:0013196 name: strand of wool synonym: "wool" RELATED [MESH:A13.970] is_a: UBERON:0010509 ! pelage hair xref: MESH:A13.970 ! wool [Term] id: UBERON:0010167 name: beard def: "the collection of hair that grows on the chin, cheeks and neck of human beings. Usually, only pubescent or adult males are able to grow beards. However, women with hirsutism may develop a beard. When differentiating between upper and lower facial hair, a beard specifically includes the moustache, which refers to hair above the upper lip and around it." [Wikipedia:Beard] is_a: UBERON:0010165 {source="FMA"} ! collection of hair on face subset: phenotype_rcn xref: FMA:54240 ! beard xref: SCTID:256924005 ! Entire beard [Term] id: UBERON:0010163 name: eyebrow def: "The eyebrow is an area of thick, delicate hairs above the eye that follows the shape of the lower margin of the brow ridges. Their main function is to protect the eye, but they are also important to human communication and facial expression. It is not uncommon for people to modify their eyebrows by means of hair addition or removal, make up, or piercings." [Wikipedia:Eyebrow] comment: AO notes: in ncit, this is an "eye appendage" is_a: UBERON:0010165 {source="FMA"} ! collection of hair on face relationship: part_of UBERON:0004088 ! ocular region subset: phenotype_rcn xref: FMA:54237 ! eyebrow xref: MESH:A01.456.505.420.338 ! eyebrow xref: ncithesaurus:Eyebrow ! Eyebrow synonym: "supercilium" RELATED LATIN [Wikipedia:Eyebrow] xref: http://upload.wikimedia.org/wikipedia/commons/2/29/Eyes_chris.jpg xref: SCTID:265781000 ! Entire eyebrow xref: UMLS:C0015420 [Term] id: UBERON:0010168 name: collection of eyelashes synonym: "cilia" EXACT LATIN [FMA:TA] synonym: "eyelashes" EXACT [FMA:70742] synonym: "eyelashes set" EXACT [FMA:70742] synonym: "set of eyelashes" EXACT [FMA:70742] intersection_of: UBERON:0010165 ! collection of hair on face intersection_of: part_of UBERON:0001702 ! eyelash xref: FMA:70742 ! set of eyelashes xref: SCTID:367575006 ! Entire eyelashes def: "A collection of hair on face that is part of a eyelash." [OBOL:automatic] [Term] id: UBERON:0010169 name: moustache def: "facial hair grown on the outer surface of the upper lip. It may or may not be accompanied by a type of beard, a facial hair style grown and cropped to cover most of the lower half of the face." [Wikipedia:Moustache] synonym: "mustache" EXACT [] is_a: UBERON:0010165 {source="FMA"} ! collection of hair on face relationship: part_of UBERON:0004089 ! midface subset: phenotype_rcn xref: FMA:59652 ! moustache xref: SCTID:256925006 ! Mustache [Term] id: UBERON:0001711 name: eyelid def: "An eyelid is a thin fold of skin that covers and protects an eyeball. With the exception of the prepuce and the labia minora, it has the thinnest skin of the whole body. The levator palpebrae superioris muscle retracts the eyelid to 'open' the eye. This can be either voluntarily or involuntarily. The human eyelid features a row of eyelashes which serve to heighten the protection of the eye from dust and foreign debris, as well as from perspiration. 'Palpebral' (and 'blepharo') means relating to the eyelids. Its key function is to regularly spread the tears and other secretion on the eye surface to keep it moist, since the cornea must be continuously moist. They keep the eyes from drying out when asleep. Moreover, the blink reflex protects the eye from foreign bodies. [WP,unvetted]." [Wikipedia:Eyelid, Wikipedia:Eyelid] comment: Each eyelid consists of the following layers, starting anteriorly: (1) skin, (2) a layer of subcutaneous connective tissue, (3) a layer of striated muscle fibres of the orbicularis muscle, (4) a layer of submuscular connective tissue, (5) a fibrous layer, including the tarsal plates, (6) a layer of smooth muscle, (7) the palpebral conjunctiva. AO notes: FMA divides this into skin, fascia, conjunctiva. Consider adding 'eye surface', like MA subset: uberon_slim synonym: "blepharon" EXACT [] synonym: "blephara" RELATED PLURAL [] synonym: "palpebra" EXACT [] synonym: "palpebrae" RELATED PLURAL [] xref: EHDAA:9037 ! eyelid xref: FMA:54437 ! Eyelid xref: GAID:72 ! eyelid xref: VHOG:0000016 ! eyelid xref: MA:0000268 ! eyelid xref: OpenCyc:Mx4rvVi4m5wpEbGdrcN5Y29ycA xref: ncithesaurus:Eyelid ! Eyelid xref: BTO:0002241 ! eyelid xref: OpenCyc:Mx4rvVi4m5wpEbGdrcN5Y29ycA ! eyelid xref: EHDAA2:0000487 ! eyelid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Eye_makeup.jpg/200px-Eye_makeup.jpg xref: EMAPA:17829 ! eyelid xref: MESH:A01.456.505.420.504 ! eyelid xref: EV:0100338 ! eyelid is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000019 {source="multiple"} ! camera-type eye relationship: capable_of GO:0060082 ! eye blink reflex xref: SCTID:265782007 ! Entire eyelid xref: http://upload.wikimedia.org/wikipedia/commons/8/84/Eye_makeup.jpg property_value: has_relational_adjective "palpebral" xsd:string xref: UMLS:C0015426 [Term] id: UBERON:0001712 name: upper eyelid subset: uberon_slim synonym: "superior eyelid" EXACT [] xref: FMA:54439 ! Upper eyelid xref: VHOG:0000389 ! upper eyelid xref: MA:0001267 ! upper eyelid xref: OpenCyc:Mx4rvg4ohJwpEbGdrcN5Y29ycA xref: ncithesaurus:Upper_Eyelid ! Upper Eyelid xref: OpenCyc:Mx4rvg4ohJwpEbGdrcN5Y29ycA ! upper eyelid xref: EHDAA2:0002115 ! upper eyelid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Eye_makeup.jpg/200px-Eye_makeup.jpg xref: EMAPA:17834 ! upper of eyelid xref: EHDAA:9047 ! upper of eyelid is_a: UBERON:0001711 ! eyelid synonym: "palpebra superior" EXACT LATIN [FMA:TA, FMA:54439] xref: SCTID:244499008 ! Entire upper eyelid property_value: homology_notes "A tetrapod's eye usually has one or more eyelids that can move across its surface and protect and cleanse it. The eye of lissamphibians has a stationary upper eyelid but a movable and transparent lower one.[well established][VHOG]" xsd:string {external_class="VHOG:0000389", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.431", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0585636 [Term] id: UBERON:0001713 name: lower eyelid subset: uberon_slim synonym: "inferior eyelid" EXACT [] xref: FMA:54442 ! Lower eyelid xref: VHOG:0000388 ! lower eyelid xref: MA:0001263 ! lower eyelid xref: OpenCyc:Mx4rvW6GtJwpEbGdrcN5Y29ycA xref: XAO:0000007 ! lower eyelid xref: ncithesaurus:Lower_Eyelid ! Lower Eyelid xref: OpenCyc:Mx4rvW6GtJwpEbGdrcN5Y29ycA ! lower eyelid xref: EHDAA2:0001015 ! lower eyelid xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/84/Eye_makeup.jpg/200px-Eye_makeup.jpg xref: EMAPA:17831 ! lower of eyelid xref: EHDAA:9041 ! lower of eyelid is_a: UBERON:0001711 ! eyelid synonym: "palpebra inferior" EXACT LATIN [FMA:TA, FMA:54442] xref: AAO:0010349 ! lower eyelid xref: SCTID:362528002 ! Entire lower eyelid property_value: homology_notes "A tetrapod's eye usually has one or more eyelids that can move across its surface and protect and cleanse it. The eye of lissamphibians has a stationary upper eyelid but a movable and transparent lower one.[well established][VHOG]" xsd:string {external_class="VHOG:0000388", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.431", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0229258 [Term] id: UBERON:0010207 ! nictitating membrane name: nictitating membrane def: "A fold of the mucous membrane of the conjunctiva in many animals. At rest, it is hidden in the medial canthus. It can extend to cover part or all of the cornea to help clean the cornea." [MESH:A13.660, Wikipedia:Nictitating_membrane] comment: Taxon notes: Some reptiles, birds, and sharks have full nictitating membranes; in many mammals, a small, vestigial portion of the membrane remains in the corner of the eye. Some mammals, such as camels, polar bears, seals, and aardvarks, have full nictitating membranes[WP]. Editor notes: We exclude the shark structure for this via a taxon constraint. synonym: "third eyelid" EXACT [MESH:A13.660] synonym: "nictitans" EXACT [http://tolweb.org/Amniota] is_a: UBERON:0001711 ! eyelid relationship: part_of UBERON:0001811 ! conjunctiva relationship: only_in_taxon NCBITaxon:32524 ! Amniota relationship: never_in_taxon NCBITaxon:9606 {source="Wikipedia"} ! Homo sapiens xref: MESH:A13.660 ! nictitating membrane xref: http://en.wikipedia.org/wiki/File:Chickenblinking.jpg xref: ncithesaurus:Nictitating_Membrane ! nictitating membrane xref: UMLS:C0028058 [Term] id: UBERON:0010310 name: nictitating membrane lamina synonym: "cartilago intercipiens" EXACT [PMID:16496288] comment: Taxon notes: these laminae may consist of purely hyaline cartilage (cats and horses) or may be heavily invested with elastic fibers (dogs, pigs, and cows; Schlegel et al., 2001) def: "thin cartilage element that stiffens the nictitating membrane." [PMID:16496288] intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0010207 ! nictitating membrane [Term] id: UBERON:0010209 name: plica semilunaris of conjunctiva def: "The plica semilunaris is a small fold of bulbar conjunctiva on the medial canthus of the eye. It is loose, so that eye movements are not restricted. It is considered a vestigial organ." [Wikipedia:Plica_semilunaris_of_conjunctiva] synonym: "plica semilunaris of the conjunctiva" RELATED [Wikipedia:Plica_semilunaris_of_conjunctiva] synonym: "plica semilunaris (conjunctiva)" EXACT [FMA:59045] synonym: "semilunar fold of conjunctiva" EXACT [FMA:59045] is_a: UBERON:0005160 {source="Wikipedia"} ! vestigial structure relationship: part_of UBERON:0001811 {source="FMA"} ! conjunctiva relationship: homologous_to UBERON:0010207 {source="Wikipedia"} ! nictitating membrane relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia xref: FMA:59045 ! plica semilunaris of conjunctiva xref: SCTID:280686009 ! Entire semilunar fold of conjunctiva xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Gray1205.png/250px-Gray1205.png synonym: "plica semilunaris conjunctivae" RELATED LATIN [Wikipedia:Plica_semilunaris_of_conjunctiva] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Gray1205.png [Term] id: UBERON:0010515 name: brille def: "layer of transparent, immovable disc-shaped skin or scale covering the eyes of some animals for protection, especially in animals without eyelids. The brille has evolved from a fusion of the upper and lower eyelids." [Wikipedia:Brille] comment: Taxon notes: In snakes, there is no eyelid and the brille is clear and cannot be distinguished except when the animal is becoming ready for ecdysis. At that time, it becomes cloudy and is visible as a cover over the eye. When the snake moults, the brille is also shed as part of its skin. The Brilles protect their eyes from dust and dirt and gives them a "glassy-eyed" blank appearance Snakes, flap-footed lizards, night lizards, and some skinks have brilles. All geckos except those in the subfamily Eublepharinae (eyelid geckos) possess brilles. Fish also have transparent eyelids called adipose eyelids. synonym: "ocular scale" RELATED [] synonym: "eye cap" RELATED [] is_a: UBERON:0000014 ! zone of skin relationship: part_of UBERON:0000019 ! camera-type eye relationship: only_in_taxon NCBITaxon:32561 ! Sauria [Term] id: UBERON:0004089 ! midface name: midface def: "the middle of the face including the nose and its associated bony structures[MW]." [http://www.merriam-webster.com/medical/midface, HP:0000309] comment: editors note: this class is currently a union of the snout (e.g. in mouse), the midface and the lower face. Note that in MA, snout includes the whole jaw and should thus be more alike the lower face than the midface, so its placement here is not strictly accurate. In future we might introduce specific classes for each of these, and include the full parthood relationships. if this is done, then care should be taken to preserve inferences such as an abnormality of the lower face being an abnormality of the midface. synonym: "lower face" RELATED [] synonym: "midface/lower face" RELATED [] synonym: "snout" RELATED SENSU [MA:0001910] xref: MA:0001910 ! snout (also: UBERON:0006333 'snout') is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001456 ! face property_value: has_relational_adjective "midfacial" xsd:string [Term] id: UBERON:0004092 name: hypothalamus-pituitary axis def: "." [HP:0000864] is_a: UBERON:0000015 ! anatomical boundary relationship: part_of UBERON:0000949 ! endocrine system [Term] id: UBERON:0010891 name: pectoral complex muscle def: "A muscle of a pectoral girdle, pectoral fin or anterior limb." [UBERON:cjm] comment: Editor notes: the MA class belongs here, based on its current child classes intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0010708 ! pectoral complex synonym: "upper limb muscle" NARROW INCONSISTENT [FMA:9621] synonym: "muscle of upper limb" NARROW INCONSISTENT [FMA:9621] synonym: "muscle of pectoral girdle and limb" RELATED [] synonym: "muscle of pectoral girdle and wing" NARROW SENSU [NCBITaxon:8782] synonym: "pectoral girdle and fore limb muscles" EXACT [AAO:0010687] xref: AAO:0010687 ! pectoral girdle and fore limb muscles xref: FMA:9621 ! muscle of upper limb xref: MA:0000615 ! forelimb muscle property_value: external_definition "Muscles of the pectoral girdle, arm, forearm, and hand (brachium, antebrachium, manus respectively).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010687", date_retrieved="2012-06-20", source="AAO:EJS"} [Term] id: UBERON:0003662 name: forelimb muscle synonym: "wing muscle" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] alt_id: UBERON:0005634 comment: AO notes: FMA and MA class actually refer to muscles of entire pectoral complex synonym: "wing muscle" NARROW SENSU [Geisha:syn, NCBITaxon:8782] synonym: "arm muscle system" EXACT [EHDAA2:0000141] synonym: "musculature of arm" RELATED PLURAL [] synonym: "musculature of the arm" RELATED PLURAL [] synonym: "muscle of upper limb" EXACT [FMA:9621] synonym: "fore limb muscle organ" EXACT [OBOL:automatic] synonym: "forelimb muscle organ" EXACT [OBOL:automatic] synonym: "muscle of free upper limb" EXACT [FMA:37348] xref: BTO:0000479 ! forelimb muscle xref: AAO:0000204 ! forelimb_muscles xref: FMA:37348 ! muscle of free upper limb intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002102 ! forelimb synonym: "free upper limb muscle" EXACT [FMA:37348] def: "A muscle organ that is part of a forelimb." [OBOL:automatic] [Term] id: UBERON:0001499 name: muscle of arm def: "A muscle organ that is part of an arm [Automatically generated definition]." [OBOL:automatic] comment: See notes on UBERON:0001460 for possible terminological confusion over term 'arm' synonym: "arm muscle" EXACT [MA:0000594] synonym: "arm muscle system" RELATED [EHDAA2:0000141] synonym: "upper arm / lower arm muscle" EXACT [UBERON:cjm] synonym: "muscle of upper arm or lower arm" EXACT [UBERON:cjm] xref: MA:0000594 ! arm muscle xref: EHDAA2:0000141 ! arm muscle system is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm [Term] id: UBERON:0004254 name: forelimb zeugopod muscle def: "A muscle organ that is part of a forelimb zeugopod (lower arm)[Automatically generated definition]." [OBOL:automatic] synonym: "wing zeugopod muscle" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "muscle of forearm" EXACT [FMA:37371] synonym: "lower arm muscle" EXACT [MA:0000600] synonym: "forearm muscle" EXACT [FMA:37371] xref: MA:0000600 ! lower arm muscle xref: FMA:37371 ! muscle of forearm intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002386 ! forelimb zeugopod xref: SCTID:181631004 ! Entire muscle of forearm [Term] id: UBERON:0004255 name: forelimb stylopod muscle def: "A muscle organ that is part of a forelimb stylopod (upper arm)[Automatically generated definition]." [OBOL:automatic] synonym: "wing stylopod muscle" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] comment: Editor notes: the FMA class "muscle of arm" belongs here, do not move. See notes on UBERON:0001460 for possible terminological confusion over term 'arm' synonym: "muscle of upper arm" EXACT [MA:0000606] synonym: "upper arm muscle" EXACT [MA:0000606] synonym: "muscle of arm" RELATED INCONSISTENT [FMA:37370] xref: MA:0000606 ! upper arm muscle xref: FMA:37370 ! Muscle of arm intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0003822 ! upper arm xref: SCTID:244979005 ! Entire muscle of upper arm [Term] id: UBERON:0004095 name: corticospinal tract def: "The corticospinal or pyramidal tract is a collection of axons that travel between the cerebral cortex of the brain and the spinal cord. The corticospinal tract mostly contains motor axons. It actually consists of two separate tracts in the spinal cord: the lateral corticospinal tract and the medial corticospinal tract. An understanding of these tracts leads to an understanding of why for the most part, one side of the body is controlled by the opposite side of the brain. Also the corticobulbar tract is considered to be a pyramidal tract. The corticobulbar tract carries signals that control motor neurons located in cranial nerve brain nuclei rather than motor neurons located in the spinal cord. The neurons of the pyramidal tracts are pyramidal neurons, but that is not how the pyramidal tract got its name, as most of the pyramidal neurons send their axons elsewhere. Instead, it got its name from the shape of the corticospinal axon tracts: when the pyramidal tract passes the medulla, it forms a dense bundle of nerve fibres that is shaped somewhat like a pyramid. [WP,unvetted]." [HP:0002492, Wikipedia:Corticospinal_tract] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ac/Gray684.png/200px-Gray684.png xref: BM:CST ! corticospinal tract is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002707 ! pyramidal tract synonym: "tractus corticospinalis" RELATED LATIN [Wikipedia:Corticospinal_tract] xref: http://upload.wikimedia.org/wikipedia/commons/a/ac/Gray684.png [Term] id: UBERON:0004096 name: odontoid process of cervical vertebra 2 alt_id: UBERON:0005210 def: "The toothlike process on the upper surface of the axis, which articulates with the atlas above[GAID]." [GAID:238, HP:0003310, Wikipedia:Wikipedia:Dens_(anatomy)] comment: TODO check AAO:0000721 odontoid_process -- Anterior process located between the atlantal cotyles that projects into the foramen magnum of the skull and bears facets that articulate with the lateral walls of the foramen synonym: "dens of axis" EXACT [FMA:24043] synonym: "axis dens" EXACT [FMA:24043] synonym: "odontoid process" EXACT [FMA:24043] synonym: "odontoid process of axis" EXACT [FMA:24043] synonym: "odontoid" RELATED [Wikipedia:Wikipedia:Dens_(anatomy)] synonym: "dens" EXACT [EMAPA:26535] synonym: "cervical vertebra 2 odontoid process" EXACT [MA:0002872] synonym: "axis odontoid process" EXACT [MA:0002872] xref: EMAPA:26535 ! odontoid process xref: GAID:238 ! odontoid process xref: FMA:24043 ! dens of axis xref: MA:0002872 ! cervical vertebra 2 odontoid process xref: OpenCyc:Mx4rwIYGoJwpEbGdrcN5Y29ycA ! odontoid process xref: AAO:0000721 ! odontoid process xref: MESH:A02.835.232.834.151.383.668 ! odontoid process is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0001093 ! cervical vertebra 2 xref: ncithesaurus:Odontoid_Process ! Odontoid Process xref: SCTID:181899003 ! Entire odontoid process of axis property_value: external_definition "Anterior process located between the atlantal cotyles that projects into the foramen magnum of the skull and bears facets that articulate with the lateral walls of the foramen.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000721", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} xref: UMLS:C0028881 [Term] id: UBERON:0004097 name: obsolete renin-aldosterone axis def: "." [HP:0003350] is_obsolete: true [Term] id: UBERON:0004098 name: tibial plateaux def: "." [HP:0003832] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000979 ! tibia [Term] id: UBERON:0004100 name: renal collecting system def: "The collecting duct system of the kidney consists of a series of tubules and ducts that connect the nephrons to the ureter. It participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and antidiuretic hormone." [HP:0004742, Wikipedia:Collecting_duct_system] synonym: "collecting duct system" EXACT [Wikipedia:Collecting_duct_system] synonym: "kidney collecting duct system" EXACT [Wikipedia:Collecting_duct_system] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/27/Gray1128.png/200px-Gray1128.png is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002113 ! kidney synonym: "tubulus renalis colligens" RELATED LATIN [Wikipedia:Collecting_duct_system] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray1128.png xref: SCTID:279371005 ! Renal collecting system structure [Term] id: UBERON:0004101 name: nasolabial region def: "." [HP:0005289] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000004 ! olfactory apparatus [Term] id: UBERON:0004103 name: alveolar ridge def: "one of the two jaw ridges either on the roof of the mouth between the upper teeth and the hard palate or on the bottom of the mouth behind the lower teeth[WP]. The alveolar ridges contain the sockets (alveoli) of the teeth[HP]." [Wikipedia:Alveolar_ridge, HP:0006477] comment: note that in BTO, this is part of an embryo synonym: "alveolar margin" EXACT [] synonym: "alveolar bone" EXACT [MP:0004189] synonym: "alveolar body" EXACT [MP:0004189] synonym: "alveolar process" EXACT [GAID:215] xref: BTO:0001383 ! alveolar bone xref: GAID:215 ! alveolar process xref: MESH:A02.835.232.781.324.502.125 ! alveolar process is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001708 ! jaw relationship: has_developmental_contribution_from UBERON:0008969 {source="PMID:19767574", source="Wikipedia"} ! dental follicle xref: SCTID:245790000 ! Entire alveolar ridge xref: ncithesaurus:Alveolar_Ridge ! alveolar ridge xref: UMLS:C0447411 [Term] id: UBERON:0004527 name: alveolar process of maxilla alt_id: UBERON:0001696 def: "thickened ridge of bone that contains the tooth sockets on bones that bear teeth. In humans, the tooth-bearing bones are the maxilla and the mandible. The mineral content of alveolar bone is mostly hydroxyapatite, which is also found in enamel as the main inorganic substance[WP]." [Wikipedia:Alveolar_process] synonym: "alveolar ridge of maxilla" EXACT [] synonym: "lower alveolar ridge" EXACT [] synonym: "posterior alveolar ridge" EXACT [] synonym: "alveolar margin of maxilla" EXACT [] synonym: "alveolar part of maxilla" EXACT [] synonym: "maxilla alveolar process" EXACT [] synonym: "processus alveolaris (maxilla)" EXACT [] xref: FMA:52897 ! Alveolar process of maxilla xref: MA:0001492 ! maxilla alveolar process intersection_of: UBERON:0004103 ! alveolar ridge intersection_of: part_of UBERON:0002397 ! maxilla xref: SCTID:245795005 ! Entire lower alveolar ridge xref: http://upload.wikimedia.org/wikipedia/commons/7/71/Gray157.png [Term] id: UBERON:0004528 name: alveolar ridge of mandible def: "The alveolar part of mandible is the part of the mandible, adjacent to the teeth, containing the dental alveolus. [WP,unvetted]." [Wikipedia:Alveolar_part_of_mandible] synonym: "alveolar margin of mandible" EXACT [] synonym: "alveolar part of mandible" EXACT [] synonym: "anterior alveolar ridge" EXACT [] synonym: "upper alveolar ridge" EXACT [] synonym: "alveolar process of mandible" EXACT [FMA:52832] synonym: "pars alveolaris (mandibula)" EXACT [FMA:52832] xref: FMA:52832 ! Alveolar part of mandible intersection_of: UBERON:0004103 ! alveolar ridge intersection_of: part_of UBERON:0001684 ! mandible xref: SCTID:245791001 ! Entire upper alveolar ridge synonym: "pars alveolaris mandibulae" RELATED LATIN [Wikipedia:Alveolar_part_of_mandible] xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/Mandibule.jpg [Term] id: UBERON:0005871 ! palatine process of maxilla name: palatine process of maxilla def: "The palatine process of the maxilla (palatal process), thick and strong, is horizontal and projects medialward from the nasal surface of the bone. It forms a considerable part of the floor of the nose and the roof of the mouth and is much thicker in front than behind. Its inferior surface is concave, rough and uneven, and forms, with the palatine process of the opposite bone, the anterior three-fourths of the hard palate. It is perforated by numerous foramina for the passage of the nutrient vessels; is channelled at the back part of its lateral border by a groove, sometimes a canal, for the transmission of the descending palatine vessels and the anterior palatine nerve from the spheno-palatine ganglion; and presents little depressions for the lodgement of the palatine glands. When the two maxillae are articulated, a funnel-shaped opening, the incisive foramen, is seen in the middle line, immediately behind the incisor teeth. In this opening the orifices of two lateral canals are visible; they are named the incisive canals or foramina of Stenson; through each of them passes the terminal branch of the descending palatine artery and the nasopalatine nerve. Occasionally two additional canals are present in the middle line; they are termed the foramina of Scarpa, and when present transmit the nasopalatine nerves, the left passing through the anterior, and the right through the posterior canal. On the under surface of the palatine process, a delicate linear suture, well seen in young skulls, may sometimes be noticed extending lateralward and forward on either side from the incisive foramen to the interval between the lateral incisor and the canine tooth. The small part in front of this suture constitutes the premaxilla (os incisivum), which in most vertebrates forms an independent bone; it includes the whole thickness of the alveolus, the corresponding part of the floor of the nose and the anterior nasal spine, and contains the sockets of the incisor teeth. The upper surface of the palatine process is concave from side to side, smooth, and forms the greater part of the floor of the nasal cavity. It presents, close to its medial margin, the upper orifice of the incisive canal. The lateral border of the process is incorporated with the rest of the bone. The medial border is thicker in front than behind, and is raised above into a ridge, the nasal crest, which, with the corresponding ridge of the opposite bone, forms a groove for the reception of the vomer. The front part of this ridge rises to a considerable height, and is named the incisor crest; it is prolonged forward into a sharp process, which forms, together with a similar process of the opposite bone, the anterior nasal spine. The posterior border is serrated for articulation with the horizontal part of the palatine bone." [Wikipedia:Palatine_process_of_maxilla] synonym: "palatal process" RELATED [Wikipedia:Palatine_process_of_maxilla] synonym: "palatine process" RELATED [Wikipedia:Palatine_process_of_maxilla] synonym: "processus palatinus (maxilla)" EXACT [FMA:52896] synonym: "processus palatinus ossis maxillae" RELATED LATIN [Wikipedia:Palatine_process_of_maxilla] synonym: "processus palatinus maxillae" RELATED LATIN [Wikipedia:Palatine_process_of_maxilla] xref: FMA:52896 ! palatine process of maxilla is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0002397 ! maxilla relationship: part_of UBERON:0012074 {source="FMA-abduced"} ! bony part of hard palate xref: SCTID:368870009 ! Entire palatine process of maxilla xref: http://upload.wikimedia.org/wikipedia/commons/4/4a/Gray160.png [Term] id: UBERON:0004104 name: hairline def: "." [HP:0009553] is_a: UBERON:0000061 ! anatomical structure relationship: adjacent_to UBERON:0001037 ! hair relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0004106 name: crus of ear def: "horizontal piece of cartilage located outside the ear canal that divides the upper and lower parts of the ear." [HP:0009895] synonym: "crus of helical part of auricular cartilage" EXACT [] synonym: "crus of helix" EXACT [FMA:61024] xref: FMA:61024 ! Crus of helical part of auricular cartilage is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0001848 ! auricular cartilage synonym: "crus helicis" EXACT LATIN [FMA:TA, FMA:61024] xref: ncithesaurus:Crus_Helicis ! Crus Helicis xref: SCTID:362547004 ! Entire crus of helix xref: UMLS:C0229319 [Term] id: UBERON:0004108 name: clivus of occipital bone def: "Part of the cranium, the clivus is a shallow depression behind the dorsum sellC& that slopes obliquely backward. It forms a gradual sloping process at the anterior most portion of the basilar occipital bone at its junction with the sphenoid bone. On axial planes, it sits just posterior to the sphenoid sinuses. Just lateral to the clivus bilaterally is the foramen lacerum which contains the internal carotid artery, proximal to its anastamosis with the Circle of Willis. Posterior to the clivus is the basilar artery. The clivus supports the upper part of the pons." [HP:0010558, Wikipedia:Clivus_%28anatomy%29] comment: The clivus is an important landmark for checking for anatomical atlanto-occipital alignment; the clivus, when viewed on a lateral C-spine X-ray, forms a line which, if extended, is known as Wackenheim's clivus line. Wackenheim's clivus line should pass through the dens of the axis or be tangential to it. Editor note: check relationships. xref: ncithesaurus:Clivus ! Clivus xref: FMA:75747 ! clivus of occipital bone synonym: "clivus" EXACT [HP:0010558] synonym: "occipital bone clivus" EXACT [FMA:75747] synonym: "Wackenheim's clivus line" RELATED [Wikipedia:Clivus_%28anatomy%29] is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0001676 {source="FMA"} ! occipital bone relationship: adjacent_to UBERON:0001677 {source="Wikipedia"} ! sphenoid bone relationship: located_in UBERON:0008788 {source="HP:0010558"} ! posterior cranial fossa xref: SCTID:361736007 ! Entire clivus xref: http://upload.wikimedia.org/wikipedia/commons/c/c5/Clivus.png xref: UMLS:C0222724 [Term] id: UBERON:0005808 ! bone tissue of long bone name: bone tissue of long bone xref: FMA:83117 ! bone tissue of long bone intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0002495 ! long bone xref: SCTID:425475006 ! Bone tissue of long bone def: "A bone tissue that is part of a long bone." [OBOL:automatic] [Term] id: UBERON:0004109 name: cortex of humerus def: "." [HP:0010629] synonym: "cortex of the humerus" EXACT [] synonym: "compact bone of humerus" EXACT [FMA:31542] synonym: "humerus compact bone" EXACT [] synonym: "humerus cortical bone" EXACT [] xref: FMA:31542 ! compact bone of humerus intersection_of: UBERON:0001439 ! compact bone intersection_of: part_of UBERON:0000976 ! humerus [Term] id: UBERON:0005809 name: cortex of manus bone def: "." [HP:0005926] intersection_of: UBERON:0001439 ! compact bone intersection_of: part_of UBERON:0005897 ! manus bone relationship: part_of UBERON:0001442 ! skeleton of manus [Term] id: UBERON:0004112 name: muscle of middle ear def: "A muscle of head that is part of a tympanic cavity [Automatically generated definition]." [OBOL:automatic] comment: check tympanic cavity vs middle ear. the same for muscles? Consider merging with muscle of auditory ossicle. Extent in MA/NCITA is stapedius and tensor tympani synonym: "muscle of tympanic cavity" EXACT [] synonym: "tympanic cavity muscle" EXACT [] xref: MA:0000256 ! tympanic cavity muscle xref: ncithesaurus:Muscle_of_the_Tympanum ! muscle of the tympanum is_a: UBERON:0002376 ! muscle of head intersection_of: UBERON:0002376 ! muscle of head intersection_of: located_in UBERON:0004114 ! tympanic cavity relationship: part_of UBERON:0001756 ! middle ear xref: UMLS:C1513769 [Term] id: UBERON:0004113 name: muscle of auditory ossicle def: "A muscle of head that attaches_to a auditory ossicle." [OBOL:automatic] comment: Extent in FMA/SCTID is stapedius and tensor tympani. Consider merging with tympanic cavity muscle synonym: "muscle of auditory ossicles" EXACT [FMA:49026] synonym: "auditory ossicles muscle" EXACT [FMA:49026] synonym: "ossicular muscle" EXACT [FMA:49026] xref: FMA:49026 ! Muscle of auditory ossicles is_a: UBERON:0002376 ! muscle of head intersection_of: UBERON:0002376 ! muscle of head intersection_of: attaches_to UBERON:0001686 ! auditory ossicle relationship: attaches_to UBERON:0001686 ! auditory ossicle relationship: part_of UBERON:0001756 ! middle ear xref: SCTID:244778009 ! Entire ossicular muscle [Term] id: UBERON:0011859 name: internal acoustic meatus def: "The internal auditory meatus (also internal acoustic meatus, internal auditory canal, and internal acoustic canal) is a canal in the petrous bone of the temporal bone of the skull that carries nerves from inside the cranium towards the middle and inner ear compartments namely cranial nerve VII and cranial nerve VIII." [Wikipedia:Internal_auditory_meatus] comment: Alternate def: The internal acoustic meatus (or internal auditory meatus ) is an opening on the medial surface of the petrous temporal bone. It is through this passageway that the facial nerve (cranial nerve VII) and vestibulocochlear nerve (cranial nerve VIII) pass to reach their sites of innervation. The vestibulocochlear nerve divides at the internal acoustic meatus to continue as separate vestibular and cochlear components. [MURDOCH:908] is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0001846 {source="MP"} ! internal ear synonym: "internal acoustic canal" RELATED [Wikipedia:Internal_auditory_meatus] synonym: "internal acoustic meatus" RELATED [Wikipedia:Internal_auditory_meatus] synonym: "internal auditory canal" RELATED [Wikipedia:Internal_auditory_meatus] synonym: "internal auditory meatus" RELATED [Wikipedia:Internal_auditory_meatus] synonym: "porus acusticus internus" RELATED [Wikipedia:Internal_auditory_meatus] xref: Wikipedia:Internal_auditory_meatus ! internal auditory meatus xref: ncithesaurus:Internal_Auditory_Canal_of_Ear ! internal auditory canal xref: FMA:53163 ! internal acoustic meatus xref: SCTID:264484004 ! Internal auditory meatus xref: UMLS:C0149591 [Term] id: UBERON:0001352 name: external acoustic meatus def: "A tube running from the outer ear to the middle ear. The human ear canal extends from the pinna to the eardrum and is about 26 mm in length and 7 mm in diameter." [Wikipedia:External_acoustic_meatus] comment: AO notes: subdivision of head in FMA. Editor note: consider revisiting superclass after refinement of CARO/EAO, conduit may not be quite correct. Development notes: tympanic ring, which serves as support for the tympanic membrane, directs invagination of the first pharingeal cleft ectoderm to form the external acoustic meatus (EAM), which provides the outer layer of the membrane[PMID 11237469] subset: uberon_slim synonym: "auditory canal" EXACT [] synonym: "ear canal" EXACT [Wikipedia:Ear_canal] synonym: "external auditory canal" EXACT [] synonym: "external auditory meatus" RELATED [] synonym: "external acoustic tube" EXACT [FMA:61734] synonym: "external auditory tube" EXACT [FMA:61734] synonym: "auditory meatus" RELATED [EHDAA2:0000460] xref: EHDAA:8975 ! external auditory meatus xref: FMA:61734 ! external acoustic tube xref: galen:ExternalAuditoryMeatus xref: VHOG:0000977 ! external auditory meatus xref: MA:0000260 ! external acoustic meatus xref: GAID:864 ! ear canal xref: FMA:61734 ! External acoustic tube xref: ncithesaurus:External_Acoustic_Meatus ! External Acoustic Meatus xref: OpenCyc:Mx4rvli-nZwpEbGdrcN5Y29ycA ! external auditory canal xref: EHDAA2:0000460 ! auditory meatus xref: EMAPA:17588 ! auditory meatus xref: MESH:A09.246.272.396 ! ear canal xref: EV:0100356 ! external acoustic meatus is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0001691 {source="FMA"} ! external ear relationship: develops_from UBERON:0005872 {source="PMID:11237469"} ! 1st arch pharyngeal cleft relationship: has_function_in GO:0055127 ! vibrational conductance of sound to the inner ear relationship: surrounded_by UBERON:0010065 {source="EHDAA2"} ! auditory meatus epithelium xref: SCTID:181178004 ! Entire external auditory canal xref: UMLS:C0013444 [Term] id: UBERON:0010065 name: auditory meatus epithelium is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube relationship: develops_from UBERON:0005872 {source="EHDAA2", source="PMID:16313389"} ! 1st arch pharyngeal cleft relationship: part_of UBERON:0001691 {source="EHDAA2"} ! external ear xref: EHDAA2:0004114 ! auditory meatus epithelium [Term] id: UBERON:0002364 name: tympanic membrane def: "A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted]." [Wikipedia:Tympanic_membrane, PMID:11237469] comment: most AOs consider this part of the middle ear, so we go with this and place it in the middle ear as a border to the external, although it could be considered to overlap the external ear in that it has an EAM layer as part - for this reason we do not consider middle and external ear to be spatially disjoint. Development notes: The tympanic membrane (TM) has three layers, two epithelia provided by the external acoustic meatus (EAM) and the MEC, derived respectively from the first pharyngeal cleft and pouch, and a mesenchymally derived fibrous stratum[PMID:11237469] subset: uberon_slim synonym: "ear drum" EXACT [] synonym: "eardrum" EXACT [] synonym: "myrinx" EXACT [] synonym: "lateral wall of tympanic cavity" EXACT [] synonym: "membranous wall of tympanic cavity" EXACT [] synonym: "Rivinus' membrane" EXACT [] synonym: "tympanum" RELATED [Wikipedia:Tympanic_membrane] xref: FMA:9595 ! Tympanic membrane xref: GAID:870 ! tympanic membrane xref: VHOG:0001146 ! tympanic membrane xref: MA:0000257 ! tympanic membrane xref: ncithesaurus:Tympanic_Membrane ! Tympanic Membrane xref: MESH:A09.246.397.873 ! tympanic membrane xref: XAO:0000212 ! tympanum xref: EV:0100358 ! tympanum (also: UBERON:0004114 'tympanic cavity') is_a: UBERON:0000094 {source="FMA"} ! membrane organ relationship: part_of UBERON:0001756 {source="MA"} ! middle ear relationship: overlaps UBERON:0001691 {source="cjm"} ! external ear relationship: adjacent_to UBERON:0004114 {source="cjm"} ! tympanic cavity relationship: overlaps UBERON:0001352 ! external acoustic meatus relationship: develops_from UBERON:0009213 {source="Wikipedia"} ! 1st pharyngeal membrane relationship: has_part UBERON:0005042 ! inner epithelial layer of tympanic membrane relationship: has_part UBERON:0010069 ! outer epithelial layer of tympanic membrane relationship: has_part UBERON:0010070 ! intermediate layer of tympanic membrane synonym: "paries membranaceus cavi tympani" EXACT LATIN [FMA:TA, FMA:9595] xref: SCTID:181180005 ! Entire tympanic membrane subset: organ_slim property_value: external_definition "The thin membrane which closes externally the cavity of the middle ear and is deeply sited at the bottom of the external auditory meatus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001146", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In particular, a tympanic membrane was not present in the earliest tetrapods (...). An ear utilizing a tympanic membrane evolved independently at least three times in tetrapods: (1) in the lineage that leads to anurans (frogs), (2) in the line of evolution to turtles and diapsids, and (3) in the late synapsid lineage that gave rise to mammals.[well established][VHOG]" xsd:string {external_class="VHOG:0001146", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.418", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0041445 [Term] id: UBERON:0010071 name: layer of tympanic membrane comment: In mammals, this class groups together the two epithelial layers plus the intermediate fibrous layer subset: grouping_class synonym: "tympanic membrane layer" EXACT [FMA:56732] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002364 ! tympanic membrane xref: FMA:56732 ! layer of tympanic membrane [Term] id: UBERON:0009647 name: tympanic membrane epithelium def: "One of the two epithelia which make up the tympanic membrane (along with the fibrous layer)" [PMID:11237469, UBERON:cjm] synonym: "tympanic epithelium" EXACT [MA:0001224] synonym: "tympanic membrane epithelial layer" EXACT [] is_a: UBERON:0010071 ! layer of tympanic membrane intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002364 ! tympanic membrane xref: MA:0001224 ! tympanic epithelium xref: ncithesaurus:Tympanic_Epithelium ! Tympanic Epithelium xref: SCTID:70839004 ! Epithelial layer of tympanic membrane xref: UMLS:C1711401 [Term] id: UBERON:0010069 name: outer epithelial layer of tympanic membrane def: "A portion of the external acoustic meatus epithelium which makes up the outer (cuticular) layer of the tympanic membrane" [PMID:11237469, UBERON:cjm] synonym: "cuticular stratum of tympanic membrane" EXACT [FMA:56819] synonym: "outer cuticular layer of tympanic membrane" EXACT [FMA:56819] synonym: "outer layer of tympanic membrane" EXACT [] synonym: "tympanic membrane external acoustic meatus epithelial component" EXACT [UBERON:cjm] intersection_of: UBERON:0009647 ! tympanic membrane epithelium intersection_of: part_of UBERON:0001352 ! external acoustic meatus xref: FMA:56819 ! Cuticular layer of tympanic membrane xref: SCTID:39725007 ! Outer epithelial layer of tympanic membrane synonym: "cuticular layer of tympanic membrane" EXACT [FMA:56819] [Term] id: UBERON:0010070 name: intermediate layer of tympanic membrane def: "The intermediate fibrous layer of the tympanic membrane." [PMID:11237469, https://sourceforge.net/tracker/?func=detail&aid=3468783&group_id=76834&atid=1205376] comment: AO notes: check MA synonym: "connective tissue layer of tympanic membrane" EXACT [FMA:56830] synonym: "fibrous stratum of tympanic membrane" EXACT [FMA:56830] synonym: "intermediate fibrous layer of tympanic membrane" EXACT [FMA:56830] is_a: UBERON:0010071 {source="FMA"} ! layer of tympanic membrane xref: FMA:56830 ! fibrous layer of tympanic membrane synonym: "fibrous layer of tympanic membrane" EXACT [FMA:56830] xref: MA:0001223 ! tympanic endothelium xref: SCTID:44692008 ! Connective tissue layer of tympanic membrane disjoint_from: UBERON:0009647 ! tympanic membrane epithelium synonym: "tympanic endothelium" EXACT [MA:0001223] [Term] id: UBERON:0005042 name: inner epithelial layer of tympanic membrane def: "A portion of the tympanic cavity epithelium which makes up the outer (cuticular) layer of the tympanic membrane" [PMID:11237469, UBERON:cjm] comment: AO notes: in FMA this is classified as a mucosa synonym: "mucous layer of tympanic membrane" EXACT [FMA:56844] synonym: "mucous stratum of tympanic membrane" EXACT [FMA:56844] synonym: "mucosa of tympanic membrane" EXACT [FMA:56844] synonym: "tympanic membrane external middle ear cavity epithelial component" EXACT [UBERON:cjm] xref: FMA:56844 ! mucosa of tympanic membrane synonym: "mucosa of tympanic membrane" EXACT [FMA:56844] intersection_of: UBERON:0009647 ! tympanic membrane epithelium intersection_of: part_of UBERON:0010063 ! tympanic cavity epithelium xref: SCTID:36411006 ! Inner epithelial layer of tympanic membrane synonym: "tympanic membrane mucosa" EXACT [FMA:56844] [Term] id: UBERON:0010063 ! tympanic cavity epithelium name: tympanic cavity epithelium is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: located_in UBERON:0004114 ! tympanic cavity relationship: develops_from_part_of UBERON:0010020 {source="EHDAA2"} ! tubotympanic recess epithelium relationship: part_of UBERON:0001756 {source="EHDAA2"} ! middle ear xref: EHDAA2:0004116 ! tympanic cavity epithelium [Term] id: UBERON:0004114 ! tympanic cavity name: tympanic cavity def: "small cavity surrounding the bones of the middle ear." [Wikipedia:Tympanic_cavity] synonym: "anatomical cavity of middle ear" EXACT [OBOL:automatic] synonym: "cavity of middle ear" EXACT [OBOL:automatic] synonym: "middle ear cavity" EXACT [OBOL:automatic] synonym: "middle-ear cavity" EXACT [OBOL:automatic] synonym: "tympanum" RELATED [BTO:0002098] synonym: "cavitas tympani" EXACT LATIN [Wikipedia:Tympanic_cavity] xref: FMA:56461 ! tympanic cavity xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/19/Gray923.png/200px-Gray923.png xref: BTO:0002098 ! tympanum xref: EV:0100358 ! tympanum (also: UBERON:0002364 'tympanic membrane') xref: SCTID:362551002 ! Entire tympanic cavity xref: EHDAA2:0004119 ! tympanic cavity lumen is_a: UBERON:0010064 {source="EHDAA2"} ! open anatomical space intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: enclosed_by UBERON:0001756 ! middle ear relationship: part_of UBERON:0001756 ! middle ear relationship: developmentally_replaces UBERON:0005625 {source="EHDAA2"} ! tubotympanic recess relationship: surrounds UBERON:0001686 ! auditory ossicle relationship: surrounded_by UBERON:0010063 ! tympanic cavity epithelium xref: http://upload.wikimedia.org/wikipedia/commons/1/19/Gray923.png [Term] id: UBERON:0002393 ! pharyngotympanic tube name: pharyngotympanic tube def: "Organ with organ cavity which connects the cavity of the middle ear to the cavity of the pharynx. Examples: There are only two pharyngotympanic tubes, the right and the left pharyngotympanic tubes.[FMA]" [Wikipedia:Eustachian_tube, FMA:FMA] comment: Editor notes: we follow FMA in making this an organ, but include a separate class for the part that is epithelium, which is equivalent to the EHDAA2 structure. From this we infer the developmental relationship subset: uberon_slim synonym: "auditory tube" EXACT [MA:0000255] synonym: "eustachian tube" RELATED [] synonym: "internal auditory tube" EXACT [] synonym: "tuba pharyngotympanica" RELATED LATIN [] synonym: "tuba auditiva" EXACT LATIN [FMA:TA, FMA:9705] synonym: "tuba auditoria" EXACT LATIN [FMA:TA, FMA:9705] xref: FMA:9705 ! Pharyngotympanic tube xref: GAID:869 ! eustachian tube xref: VHOG:0001145 ! auditory tube xref: MA:0000255 ! auditory tube xref: XAO:0000213 ! auditory tube xref: AAO:0011016 ! auditory tube xref: AAO:0000146 ! eustachian canal xref: ncithesaurus:Eustachian_Tube ! Eustachian Tube xref: EMAPA:17601 ! pharyngo-tympanic tube xref: EV:0100359 ! auditory tube is_a: UBERON:0000062 {source="FMA"} ! organ relationship: part_of UBERON:0001756 ! middle ear relationship: has_developmental_contribution_from UBERON:0010020 {source="UBERON:0010062"} ! tubotympanic recess epithelium relationship: has_part UBERON:0010062 ! pharyngotympanic tube epithelium subset: organ_slim synonym: "tuba auditiva; tuba auditoria; tuba auditivea" RELATED LATIN [Wikipedia:Eustachian_tube] xref: http://upload.wikimedia.org/wikipedia/commons/4/40/Ear-anatomy-text-small-en.svg property_value: external_definition "Furrow on the ventral surface of the otic capsule, and occasionally also the parasphenoid, that houses the Eustachian tube.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000146", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000146", date_retrieved="2012-06-20"} property_value: external_definition "The narrow channel connecting the nasopharynx and the middle ear. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001145", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/auditory+tube", source="http://bgee.unil.ch/"} property_value: homology_notes "The tympanic cavity and auditory tube of an amniote develop from the first embryonic pharyngeal pouch, so they are homologous to the first gill pouch, or spiracle, of a fish. We are uncertain whether this homology strictly applies to the middle ear cavity and auditory tube of lissamphibians, which show certain peculiarities in their development.[uncertain][VHOG]" xsd:string {external_class="VHOG:0001145", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.417", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0015183 [Term] id: UBERON:0010062 ! pharyngotympanic tube epithelium name: pharyngotympanic tube epithelium is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube relationship: develops_from_part_of UBERON:0010020 {source="EHDAA2"} ! tubotympanic recess epithelium relationship: part_of UBERON:0002393 {source="cjm"} ! pharyngotympanic tube synonym: "auditory tube epithelium" EXACT [EHDAA2:0004117] synonym: "eustachian tube epithelium" EXACT [UBERON:cjm] xref: EHDAA2:0004117 ! auditory tube epithelium [Term] id: UBERON:0009692 name: lumen of pharyngotympanic tube comment: Editors note: Check relationships for conformance with AAO and XAO synonym: "lumen of auditory tube" EXACT [FMA:60079] synonym: "lumen of eustachian tube" EXACT [FMA:60079] synonym: "pharyngotympanic tube lumen" EXACT [FMA:60079] is_a: UBERON:0005082 {source="EHDAA2"} ! tube lumen intersection_of: UBERON:0002558 ! organ cavity intersection_of: part_of UBERON:0002393 ! pharyngotympanic tube relationship: developmentally_replaces UBERON:0005625 {source="EHDAA2/Kardong"} ! tubotympanic recess relationship: surrounded_by UBERON:0010062 {source="cjm"} ! pharyngotympanic tube epithelium relationship: continuous_with UBERON:0010060 ! pharyngeal opening of pharyngotympanic tube xref: FMA:60079 ! lumen of pharyngotympanic tube xref: EHDAA2:0004118 ! auditory tube lumen synonym: "auditory tube lumen" EXACT [EHDAA2:0004118] [Term] id: UBERON:0010060 ! pharyngeal opening of pharyngotympanic tube name: pharyngeal opening of pharyngotympanic tube def: "On the lateral wall of the nasal part of the pharynx is the pharyngeal opening of auditory tube (pharyngeal ostium), somewhat triangular in shape, and bounded behind by a firm prominence, the torus or cushion, caused by the medial end of the cartilage of the tube which elevates the mucous membrane." [Wikipedia:Pharyngeal_opening_of_auditory_tube] synonym: "pharyngeal ostium" RELATED [Wikipedia:Pharyngeal_opening_of_auditory_tube] synonym: "ostium pharyngeum tubae auditivae" EXACT LATIN [FMA:TA] synonym: "ostium pharyngeum tubae auditoriae" EXACT LATIN [FMA:TA] synonym: "pharyngeal opening of auditory tube" EXACT [FMA:54979] synonym: "pharyngeal opening of eustachian tube" EXACT [FMA:54979] synonym: "pharyngeal orifice of auditory tube" EXACT [FMA:54979] synonym: "pharyngeal orifice of eustachian tube" EXACT [FMA:54979] synonym: "pharyngeal orifice of pharyngotympanic tube" EXACT [FMA:54979] synonym: "pharyngeal ostium of auditory tube" EXACT [FMA:54979] synonym: "pharyngeal ostium of eustachian tube" EXACT [FMA:54979] synonym: "pharyngeal ostium of pharyngotympanic tube" EXACT [FMA:54979] synonym: "pharyngeal tubal ostium" EXACT [FMA:54979] is_a: UBERON:0000464 ! anatomical space relationship: continuous_with UBERON:0010061 ! lumen of nasopharynx xref: FMA:54979 ! pharyngeal opening of pharyngotympanic tube synonym: "ostium pharyngeum tubae auditivae" RELATED LATIN [Wikipedia:Pharyngeal_opening_of_auditory_tube] xref: http://upload.wikimedia.org/wikipedia/commons/1/1b/Gray1029.png xref: SCTID:368945008 ! Entire pharyngeal ostium of Eustachian tube [Term] id: UBERON:0013526 name: otocyst lumen is_a: UBERON:0007473 {source="EHDAA2"} ! lumen of epithelial sac relationship: develops_from UBERON:0006273 {source="EHDAA2"} ! otic pit relationship: located_in UBERON:0003051 {source="EHDAA2"} ! ear vesicle intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: part_of UBERON:0003051 ! ear vesicle xref: EHDAA2:0004121 ! otocyst lumen xref: EMAPA:25363 ! lumen of otocyst synonym: "lumen of otocyst" EXACT [EMAPA:25363] [Term] id: UBERON:0010061 ! lumen of nasopharynx name: lumen of nasopharynx synonym: "nasopharynx lumen" EXACT [FMA:55094] synonym: "nasopharynx cavity" EXACT [] synonym: "nasopharyngeal luman" EXACT [] is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001731 ! cavity of pharynx xref: FMA:55094 ! lumen of nasopharynx [Term] id: UBERON:0007354 name: cartilage of pharyngotympanic tube def: "The cartilage of pharyngotympanic tube, about 24 mm. in length, is formed of a triangular plate of elastic fibrocartilage, the apex of which is attached to the margin of the medial end of the osseous portion of the tube, while its base lies directly under the mucous membrane of the nasal part of the pharynx, where it forms an elevation, the torus tubarius or cushion, behind the pharyngeal orifice of the tube. The upper edge of the cartilage is curled upon itself, being bent laterally so as to present on transverse section the appearance of a hook; a groove or furrow is thus produced, which is open below and laterally, and this part of the canal is completed by fibrous membrane. The cartilage lies in a groove between the petrous part of the temporal and the great wing of the sphenoid; this groove ends opposite the middle of the medial pterygoid plate. The cartilaginous and bony portions of the tube are not in the same plane, the former inclining downward a little more than the latter. The diameter of the tube is not uniform throughout, being greatest at the pharyngeal orifice, least at the junction of the bony and cartilaginous portions, and again increased toward the tympanic cavity; the narrowest part of the tube is termed the isthmus. The position and relations of the pharyngeal orifice are described with the nasal part of the pharynx. The mucous membrane of the tube is continuous in front with that of the nasal part of the pharynx, and behind with that of the tympanic cavity; it is covered with ciliated epithelium and is thin in the osseous portion, while in the cartilaginous portion it contains many mucous glands and near the pharyngeal orifice a considerable amount of adenoid tissue, which has been named by Gerlach the tube tonsil. The tube is opened during deglutition by the Salpingopharyngeus and Dilatator tubC&. The latter arises from the hook of the cartilage and from the membranous part of the tube, and blends below with the Tensor veli palatini." [Wikipedia:Cartilage_of_pharyngotympanic_tube] synonym: "cartilage of auditory tube" EXACT [FMA:60096] synonym: "cartilage of eustachian tube" EXACT [FMA:60096] synonym: "pharyngotympanic tube cartilage" EXACT [FMA:60096] xref: FMA:60096 ! cartilage of pharyngotympanic tube intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0002393 ! pharyngotympanic tube synonym: "cartilago tubae auditivae" EXACT LATIN [FMA:TA, FMA:60096] synonym: "cartilago tubae auditoriae" EXACT LATIN [FMA:TA, FMA:60096] synonym: "cartilago tubae auditivae; cartilago tubae auditoriae" RELATED LATIN [Wikipedia:Cartilage_of_pharyngotympanic_tube] xref: http://upload.wikimedia.org/wikipedia/commons/b/b9/Gray915.png xref: SCTID:362565000 ! Entire cartilage of Eustachian tube [Term] id: UBERON:0007355 name: bony part of pharyngotympanic tube def: "The bony part of pharyngotympanic tube is about 12 mm. in length. It begins in the carotid wall of the tympanic cavity, below the septum canalis musculotubarii, and, gradually narrowing, ends at the angle of junction of the squama and the petrous portion of the temporal bone, its extremity presenting a jagged margin which serves for the attachment of the cartilaginous portion." [Wikipedia:Bony_part_of_pharyngotympanic_tube] synonym: "osseous portion" RELATED [Wikipedia:Bony_part_of_pharyngotympanic_tube] synonym: "bony part of auditory tube" EXACT [FMA:60057] synonym: "bony part of eustachian tube" EXACT [FMA:60057] synonym: "osseous portion of eustachian tube" EXACT [FMA:60057] synonym: "pars ossea (tuba auditiva)" EXACT [FMA:60057] synonym: "pars ossea (tuba auditoria)" EXACT [FMA:60057] xref: FMA:60057 ! bony part of pharyngotympanic tube intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0002393 ! pharyngotympanic tube synonym: "pars ossea tubae auditivae" RELATED LATIN [Wikipedia:Bony_part_of_pharyngotympanic_tube] xref: http://upload.wikimedia.org/wikipedia/commons/9/9d/Gray911.png xref: SCTID:362563007 ! Entire osseous portion of Eustachian tube [Term] id: UBERON:0010020 ! tubotympanic recess epithelium name: tubotympanic recess epithelium def: "The dorsal portion of the embryonic first endodermal pharyngeal pouch; it develops into the middle ear cavity." [http://www.biology-online.org/dictionary/Tubotympanic_recess] is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: part_of UBERON:0001756 {source="MA"} ! middle ear relationship: develops_from UBERON:0007122 {source="EHDAA2", source="ISBN10:0073040584", source="PMID:11237469"} ! pharyngeal pouch 1 xref: EHDAA2:0004115 ! tubotympanic recess epithelium [Term] id: UBERON:0005625 name: tubotympanic recess def: "The cavity formed by the tubotympanic recess epithelium." [UBERON:cjm] comment: Editor note: we follow EHDAA2 in distinguishing between the cavity and the material entity - the former develops into the middle ear cavity synonym: "tubotympanic recess lumen" EXACT [EHDAA2:0002095] synonym: "tubotympanic recess cavity" EXACT [] xref: MA:0001218 ! tubotympanic recess xref: EHDAA2:0002095 ! tubotympanic recess lumen xref: EMAPA:17002 ! tubo-tympanic recess xref: VHOG:0001297 ! tubotympanic recess xref: EHDAA:6772 ! tubotympanic recess is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001756 {source="MA"} ! middle ear relationship: develops_from UBERON:0007122 {source="ISBN10:0073040584"} ! pharyngeal pouch 1 relationship: surrounded_by UBERON:0010020 {source="EHDAA2"} ! tubotympanic recess epithelium xref: ncithesaurus:Tubotympanic_Recess ! Tubotympanic Recess xref: SCTID:361516008 ! Tubotympanic recess property_value: external_definition "A diverticulum formed by the dorsal portion of the 1st pharyngeal pouch and that forms the middle ear cavity. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.73-74, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001297", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The tympanic cavity and auditory tube of an amniote develop from the first embryonic pharyngeal pouch, so they are homologous to the first gill pouch, or spiracle, of a fish. We are uncertain whether this homology strictly applies to the middle ear cavity and auditory tube of lissamphibians, which show certain peculiarities in their development.[well established][VHOG]" xsd:string {external_class="VHOG:0001297", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.417", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1284046 [Term] id: UBERON:0004115 name: blood vessel of tympanic cavity def: "A blood vessel that is part of a tympanic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "tympanic cavity blood vessel" EXACT [] synonym: "middle ear blood vessel" EXACT [] synonym: "anatomical cavity of middle ear blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of anatomical cavity of middle ear" EXACT [OBOL:automatic] synonym: "blood vessel of cavity of middle ear" EXACT [OBOL:automatic] synonym: "blood vessel of middle ear anatomical cavity" EXACT [OBOL:automatic] synonym: "blood vessel of middle ear cavity" EXACT [OBOL:automatic] synonym: "cavity of middle ear blood vessel" EXACT [OBOL:automatic] synonym: "middle ear anatomical cavity blood vessel" EXACT [OBOL:automatic] synonym: "middle ear cavity blood vessel" EXACT [OBOL:automatic] xref: MA:0001219 ! tympanic cavity blood vessel is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: located_in UBERON:0004114 ! tympanic cavity relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0004116 name: nerve of tympanic cavity def: "A nerve that is part of a tympanic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "tympanic cavity nerve" EXACT [] synonym: "anatomical cavity of middle ear nerve" EXACT [OBOL:automatic] synonym: "cavity of middle ear nerve" EXACT [OBOL:automatic] synonym: "middle ear anatomical cavity nerve" EXACT [OBOL:automatic] synonym: "middle ear cavity nerve" EXACT [OBOL:automatic] synonym: "nerve of anatomical cavity of middle ear" EXACT [OBOL:automatic] synonym: "nerve of cavity of middle ear" EXACT [OBOL:automatic] synonym: "nerve of middle ear anatomical cavity" EXACT [OBOL:automatic] synonym: "nerve of middle ear cavity" EXACT [OBOL:automatic] synonym: "tympanic cavity nerves" EXACT [MA:0001222] xref: MA:0001222 ! tympanic cavity nerves is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: located_in UBERON:0004114 ! tympanic cavity relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0004138 name: somitomeric trunk muscle def: "The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.[GO]." [GO:0002075] comment: TODO - find N+S conditions. SMT & develops_from somite is not specific enough (all SMT develops_from somite) is_a: UBERON:0001134 ! skeletal muscle tissue relationship: develops_from UBERON:0002329 ! somite [Term] id: UBERON:0007100 ! circulatory organ name: circulatory organ def: "A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507] comment: editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis. Gene notes: Bmp, Nkx, Gata subset: grouping_class synonym: "adult heart" RELATED [FBbt:00003154] synonym: "heart" NARROW [GO:0007507] synonym: "heart or heart like organ" EXACT [] synonym: "cardiac structure" RELATED [] synonym: "cardiac pump" EXACT [] synonym: "dorsal tube" NARROW [Wikipedia:Heart] xref: FBbt:00003154 ! adult heart xref: TADS:0000147 ! adult heart xref: ANISEED:1235302 ! Heart is_a: UBERON:0003103 ! compound organ relationship: part_of UBERON:0001009 ! circulatory system relationship: present_in_taxon NCBITaxon:7718 {source="PMID:20959416"} ! Ciona xref: http://www.sciencemag.org/content/313/5795/1922/F1.large.jpg [Term] id: UBERON:0000948 name: heart def: "a myogenic muscular organ found in the cardiovascular system. It is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions. The vertebrate heart is composed of cardiac muscle, which is an involuntary striated muscle tissue found only in this organ, and connective tissue. Primitive fish have a four-chambered heart; however, the chambers are arranged sequentially so that this primitive heart is quite unlike the four-chambered hearts of mammals and birds. The first chamber is the sinus venosus, which collects de-oxygenated blood, from the body, through the hepatic and cardinal veins. From here, blood flows into the atrium and then to the powerful muscular ventricle where the main pumping action takes place. The fourth and final chamber is the conus arteriosus which contains several valves and sends blood to the ventral aorta. The ventral aorta delivers blood to the gills where it is oxygenated and flows, through the dorsal aorta, into the rest of the body. (In tetrapods, the ventral aorta has divided in two; one half forms the ascending aorta, while the other forms the pulmonary artery. In the adult fish, the four chambers are not arranged in a straight row but, instead, form an S-shape with the latter two chambers lying above the former two. This relatively simpler pattern is found in cartilaginous fish and in the more primitive ray-finned fish. In teleosts, the conus arteriosus is very small and can more accurately be described as part of the aorta rather than of the heart proper. The conus arteriosus is not present in any amniotes which presumably having been absorbed into the ventricles over the course of evolution. Similarly, while the sinus venosus is present as a vestigial structure in some reptiles and birds, it is otherwise absorbed into the right atrium and is no longer distinguishable[WP]." [Wikipedia:Heart] comment: note that we use the term 'circulatory organ' for the generic class. Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepi- thelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" doi:10.1101/gad.1485706 subset: uberon_slim subset: vertebrate_core subset: major_organ synonym: "chambered heart" EXACT [UBERON:cjm] synonym: "vertebrate heart" EXACT [] synonym: "branchial heart" NARROW SENSU [] synonym: "Herz" RELATED [BTO:0000562] xref: BILA:0000020 xref: BTO:0000562 xref: EFO:0000815 ! heart xref: EHDAA:420 ! heart xref: FMA:7088 ! Heart xref: GAID:174 ! heart xref: galen:Heart xref: VHOG:0000276 ! heart xref: MA:0000072 ! heart xref: MAT:0000036 ! heart xref: MIAA:0000036 ! heart xref: OpenCyc:Mx4rvVjvDpwpEbGdrcN5Y29ycA xref: TAO:0000114 ! heart xref: XAO:0000064 ! heart xref: ZFA:0000114 ! heart xref: ncithesaurus:Heart ! Heart xref: EHDAA2:0000738 ! heart xref: EMAPA:16105 ! heart xref: MESH:A07.541 ! heart xref: EV:0100018 ! heart xref: AAO:0010210 ! heart intersection_of: UBERON:0007100 ! circulatory organ intersection_of: has_part UBERON:0004151 ! cardiac chamber relationship: part_of UBERON:0004535 ! cardiovascular system relationship: develops_from UBERON:0004141 ! heart tube relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: AAO:0010210 ! heart xref: SCTID:302509004 ! Entire heart subset: organ_slim property_value: external_definition "Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010210", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: axiom_lost_from_external_ontology "relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010210", date_retrieved="2012-06-20"} property_value: external_definition "Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000114", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: homology_notes "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]" xsd:string {external_class="VHOG:0000276", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.481", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "cardiac" xsd:string xref: UMLS:C0018787 [Term] id: UBERON:0004140 ! heart field name: heart field comment: note that this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] def: "a specific region of the lateral mesoderm in which the heart will develop." [GO:0003128] synonym: "primary heart field" EXACT [XAO:0004185, PMID:17276708] is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0003081 {source="GO:0003128"} ! lateral plate mesoderm xref: XAO:0004185 ! primary heart field [Term] id: UBERON:0009889 ! secondary heart field name: secondary heart field def: "extra-cardiac population of mesodermal progenitors that gives rise to the right ventricle and outflow tract." [PMID:17276708] comment: Taxon notes: "In general, the two studies in chick concluded that the contribution of the SHF was to the outflow tract, whereas the mouse work suggested that the second lineage contributed more broadly to the heart, including the outflow tract and much or all of the right ventricle [11–14]. These different conclusions may represent differences in the experimental approaches used or may represent bona fide differences in the contribution of the second lineage to the hearts of birds compared to mammals [11]. Alternatively, the secondary/anterior heart fields described in the chick may represent a subset of a broader field that makes a more substantial contribution to the heart, as the mouse studies suggested" [PMID:17276708] synonym: "SHF" RELATED [XAO:0004186] synonym: "second heart field" EXACT [XAO:0004186] synonym: "anterior heart field" EXACT [PMID:17276708] synonym: "anterior/second heart field" EXACT [Geisha:syn, NCBITaxon:8782] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0000926 ! mesoderm relationship: anterior_to UBERON:0004140 {source="PMID:17276708"} ! heart field relationship: dorsal_to UBERON:0004140 {source="PMID:17276708"} ! heart field xref: XAO:0004186 ! secondary heart field [Term] id: UBERON:0009751 name: cardiac mesenchyme def: "the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures" [MP:0011264] comment: Editor note: decide whether to merge with cardiac mesoderm. Check start/end stages xref: EHDAA2:0004162 ! heart mesenchyme is_a: UBERON:0000477 {source="EHDAA2"} ! anatomical cluster intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0007005 ! cardiac mesoderm name: cardiac mesoderm def: "the splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]." [http://www.drugs.com/dict/cardiogenic-mesoderm.html, XAO:0000235] comment: consider FBbt:00005541 ! cardiogenic mesoderm synonym: "heart primordia" RELATED [XAO:0000235] synonym: "cardiogenic mesoderm" RELATED [http://www.drugs.com/dict/cardiogenic-mesoderm.html] xref: EHDAA:385 ! cardiogenic xref: BILA:0000051 ! cardiac mesoderm xref: XAO:0000235 ! cardiac mesoderm xref: VHOG:0001641 ! cardiac mesoderm is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0004140 ! heart field relationship: part_of UBERON:0009881 ! anterior lateral plate mesoderm relationship: develops_from UBERON:0004872 ! splanchnic layer of lateral plate mesoderm relationship: induced_by UBERON:0009881 ! anterior lateral plate mesoderm xref: AAO:0011021 ! cardiac mesoderm xref: SCTID:360387000 ! Cardiogenic mesoderm xref: EFO:0000315 ! cardiac mesoderm primordium [Term] id: UBERON:0003084 name: heart primordium def: "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone." [ZFIN:curator] comment: editor note: should probably be fused with heart rudiment. subset: uberon_slim synonym: "fused heart primordium" RELATED [] xref: XAO:0000336 ! fused heart primordium xref: ZFA:0000028 ! heart primordium xref: BTO:0001887 ! heart primordium is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: part_of UBERON:0004535 {source="ZFA"} ! cardiovascular system relationship: develops_from UBERON:0004140 ! heart field relationship: develops_from UBERON:0003081 {source="ZFA"} ! lateral plate mesoderm relationship: develops_from UBERON:0007005 {source="XAO"} ! cardiac mesoderm xref: ncithesaurus:Primordium_of_the_Heart ! Primordium of the Heart xref: AAO:0011044 ! fused heart primordium xref: TAO:0000028 ! heart primordium property_value: external_definition "The fused aspects of ventral mesoderm, which have migrated from either side of the prechordal plate, and fused ventrally, just behind the cement gland. They will give rise to the endocardium at NF stage 27&28.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011044", date_retrieved="2012-06-20", source="XAO:curator"} property_value: external_definition "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000028", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from lateral mesoderm (TAO:0001065)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000028", date_retrieved="2012-08-14"} xref: UMLS:C1514450 [Term] id: UBERON:0004291 name: heart rudiment def: "a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GO:0003313] synonym: "heart cone" EXACT [GO:0003313] synonym: "rudimentary heart" EXACT [ZFA:0000115] xref: ZFA:0000115 ! heart rudiment is_a: UBERON:0000483 ! epithelium relationship: develops_from UBERON:0003084 {source="ZFA"} ! heart primordium relationship: develops_from UBERON:0004139 ! cardiogenic plate xref: TAO:0000115 ! heart rudiment property_value: external_definition "The migrating myocardial precursors of the heart rudiment form a cone like structure between 19.5hpf and 22hpf, and eventually telescope out into the primitive heart tube at 24hpf. Stainier 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000115", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0004139 ! cardiogenic plate name: cardiogenic plate def: "The first recognizable structure derived from the heart field" [GO:0003142] comment: TODO - check plate vs rudiment vs primordium vs endocardial tube. See XAO synonym: "heart rudiment" RELATED [] synonym: "cardiogenic crescent" RELATED [GO:0003142] synonym: "myocardial plate" EXACT [EHDAA2:0000215] xref: EMAPA:16106 ! cardiogenic plate xref: VHOG:0000975 ! cardiogenic plate xref: EHDAA2:0000215 ! myocardial plate is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0003084 ! heart primordium property_value: homology_notes " (In vertebrates) The embryonic mesoderm is the source of both the cardiogenic plate, giving rise to the future myocardium as well as the endocardium that will line the system on the inner side.[well established][VHOG]" xsd:string {external_class="VHOG:0000975", ontology="VHOG", source="PMID:15611355 Gittenberger-de Groot AC\, Bartelings MM\, Deruiter MC\, Poelmann RE\, Basics of cardiac development for the understanding of congenital heart malformations. Pediatric Research (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005498 ! primitive heart tube name: primitive heart tube def: "Multi-tissue structure that arises from the heart rudiment and will become the heart tube." [ZFA:0000149] subset: vertebrate_core xref: ZFA:0000149 ! primitive heart tube xref: EHDAA2:0001512 ! primitive heart tube xref: EMAPA:16215 ! primitive heart tube xref: EHDAA:436 ! primitive heart tube is_a: UBERON:0000481 ! multi-tissue structure relationship: develops_from UBERON:0004291 {source="ZFA"} ! heart rudiment xref: SCTID:361522004 ! Entire primitive heart tube xref: TAO:0000149 ! primitive heart tube [Term] id: UBERON:0004141 ! heart tube name: heart tube def: "Cavitated compound organ that will become the adult heart following looping morphogenesis and valve formation[ZFA]." [GO:0003143, ZFA:0000360] subset: vertebrate_core synonym: "embryonic heart tube" RELATED [] synonym: "early primitive heart tube" EXACT [EMAPA:16208] xref: ZFA:0000360 ! heart tube xref: EMAPA:16208 ! early primitive heart tube xref: EHDAA:424 ! early primitive heart tube xref: EFO:0003526 ! heart tube xref: XAO:0000337 ! endocardial tube xref: AAO:0010411 ! endocardial tube is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0002050 {source="XAO"} ! embryonic structure relationship: develops_from UBERON:0005498 {source="ZFA"} ! primitive heart tube xref: TAO:0000360 ! heart tube [Term] id: UBERON:0004292 name: cardiac skeleton def: "a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart[GO]. structure of dense connective tissue in the heart that separates the atria from the ventricles. It is not a true skeleton, but it does provide structure and support for the heart, as well as isolating the atria from the ventricles. This allows the AV node and AV bundle to delay the wave of depolarisation such that the atria can contract and assist in ventricular filling before the ventricles themselves depolarise and contract (the AV bundle is the only part of the conduction system that passes from the atria to the ventricles in a normal heart). It also allows the valves (bicuspid, tricuspid, semilunar) to keep open by giving them structural support." [Wikipedia:Cardiac_skeleton] synonym: "cardiac fibrous skeleton" EXACT [] synonym: "heart fibrous skeleton" EXACT [] synonym: "fibrous skeleton of heart" EXACT [] synonym: "skeleton of heart" EXACT [FMA:9496] xref: FMA:9496 ! fibrous skeleton of heart is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0000948 ! heart relationship: adjacent_to UBERON:0002081 ! cardiac atrium relationship: adjacent_to UBERON:0002082 ! cardiac ventricle synonym: "trigonum fibrosum dextrum cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "trigona fibrosa" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "trigonum fibrosum sinistrum cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "anulus fibrosus dexter cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "anulus fibrosus sinister cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] xref: http://upload.wikimedia.org/wikipedia/commons/5/50/Gray495.png [Term] id: UBERON:0004143 name: membranous septum def: "The membranous septum is the upper part of ventricular septum." [GO:0003149] is_a: UBERON:0003037 ! septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: UBERON:0004144 name: muscular septum def: "The muscular septum is the lower part of the ventricular septum" [GO:0003150] is_a: UBERON:0003037 ! septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: UBERON:0003983 name: conus arteriosus def: "a conical pouch formed from the upper and left angle of the right ventricle in the chordate heart, from which the pulmonary artery arises[WP]. the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminates in the pulmonary trunk[MP]." [MP:0009464, Wikipedia:Conus_arteriosus] comment: Terminology notes: we use the term CA for the anterior chamber if it is composed of cardiac muscle, contractile, and contains conal valves internally[Kardong] Taxon notes: Kardong says absent in adult tetrapods, check AAO xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/46/Gray492.png/200px-Gray492.png is_a: UBERON:0004151 ! cardiac chamber relationship: part_of UBERON:0002080 ! right ventricle xref: AAO:0010250 ! conus arteriosus xref: http://upload.wikimedia.org/wikipedia/commons/4/46/Gray492.png property_value: external_definition "Receives blood from the left atrium and becomes the median truncus arteriosus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010250", date_retrieved="2012-06-20", source="AAO:BJB"} [Term] id: UBERON:0004152 name: bulbus arteriosus def: "The bulbus arteriosus is an elastic heart chamber[GO]. Multi-tissue structure that consists of three layers and through which the blood exits the heart. The bulbus arteriosus is a pear shaped chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches[ZFA]." [GO:0003232, PMID:15108157] comment: Evolution notes: replaces conus arteriosis in cartilaginous fish synonym: "truncus" EXACT [ZFA:0000173] xref: ZFA:0000173 ! bulbus arteriosus (also: UBERON:0004706 'bulbus cordis') xref: EFO:0003505 ! bulbus arteriosus is_a: UBERON:0004151 ! cardiac chamber relationship: develops_from UBERON:0007287 {evidence="definitional"} ! presumptive bulbus arteriosus xref: TAO:0000173 ! bulbus arteriosus (also: UBERON:0004706 'bulbus cordis') property_value: external_definition "A pear shaped chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches. The bulbus arteriosus has three distinct layers. Hu et al. 2000.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000173", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0004145 ! outflow tract name: outflow tract def: "The outflow tract is the portion of the heart through which blood flows into the arteries" [GO:0003151] synonym: "cardiac outflow tract" EXACT [] xref: MA:0000100 ! outflow tract xref: EMAPA:16229 ! outflow tract of primitive heart tube xref: EMAPA:16346 ! outflow tract of heart xref: VHOG:0000670 ! outflow tract xref: EHDAA:464 ! outflow tract xref: EHDAA:798 ! outflow tract xref: EHDAA2:0001351 ! outflow tract is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0000948 ! heart xref: XAO:0004139 ! outflow tract [Term] id: UBERON:0005337 name: outflow tract of ventricle def: "A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]." [Wikipedia:Ventricular_outflow_tract] synonym: "outflow part of ventricle" EXACT [] synonym: "ventricular outflow tract" EXACT [Wikipedia:Ventricular_outflow_tract] synonym: "heart ventricle outflow tract" EXACT [MP:0010224] xref: FMA:13225 ! Outflow part of ventricle intersection_of: UBERON:0004145 ! outflow tract intersection_of: part_of UBERON:0002082 ! cardiac ventricle xref: XAO:0004140 ! ventricular outflow tract [Term] id: UBERON:0005953 name: outflow part of right ventricle def: "Outflow part of ventricle which is continuous with the pulmonary trunk[FNA]. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery[WP]." [FMA:7216] synonym: "conus arteriosus (infundibulum)" EXACT [FMA:7216] synonym: "infundibulum of right ventricle" EXACT [FMA:7216] synonym: "outflow tract of right ventricle" EXACT [FMA:7216] synonym: "pulmonary conus" EXACT [FMA:7216] synonym: "infundibulum" BROAD [Wikipedia:Conus_arteriosus] synonym: "right ventricular outflow tract" EXACT [] synonym: "RVOT" EXACT [] xref: FMA:7216 ! outflow part of right ventricle intersection_of: UBERON:0005337 ! outflow tract of ventricle intersection_of: part_of UBERON:0002080 ! right ventricle relationship: continuous_with UBERON:0002333 ! pulmonary trunk relationship: develops_from UBERON:0009889 {source="PMID:17276708"} ! secondary heart field xref: SCTID:244379003 ! Entire right ventricular outflow tract xref: ncithesaurus:Infundibulum ! infundibulum xref: UMLS:C1881209 [Term] id: UBERON:0005956 ! outflow part of left ventricle name: outflow part of left ventricle def: "Outflow part of ventricle which is continuous with the aorta[FMA]. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]." [FMA:9473] synonym: "aortic vestibule" EXACT [FMA:9473] synonym: "left ventricular outflow" EXACT [FMA:9473] synonym: "outflow tract of left ventricle" EXACT [FMA:9473] synonym: "left ventricular outflow tract" EXACT [HP:0011103] synonym: "LVOT" EXACT [] xref: FMA:9473 ! outflow part of left ventricle intersection_of: UBERON:0005337 ! outflow tract of ventricle intersection_of: part_of UBERON:0002084 ! left ventricle synonym: "vestibulum aortae" EXACT LATIN [FMA:TA, FMA:9473] xref: SCTID:264070001 ! Entire outflow tract of left ventricle [Term] id: UBERON:0005946 name: outflow tract of atrium synonym: "outflow part of atrium" EXACT [FMA:14141] xref: FMA:14141 ! outflow part of atrium intersection_of: UBERON:0004145 ! outflow tract intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: continuous_with UBERON:0002082 ! cardiac ventricle def: "An outflow tract that is part of a cardiac atrium." [OBOL:automatic] [Term] id: UBERON:0005965 ! outflow part of right atrium name: outflow part of right atrium def: "Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA]" [FMA:9550, FMA:FMA] synonym: "main part of right atrium" EXACT [FMA:9550] synonym: "outflow tract of right atrium" EXACT [FMA:9550] xref: FMA:9550 ! outflow part of right atrium intersection_of: UBERON:0005946 ! outflow tract of atrium intersection_of: part_of UBERON:0002078 ! right atrium [Term] id: UBERON:0005966 name: outflow part of left atrium synonym: "main part of left atrium" EXACT [FMA:9551] synonym: "outflow tract of left atrium" EXACT [FMA:9551] xref: FMA:9551 ! outflow part of left atrium intersection_of: UBERON:0005946 ! outflow tract of atrium intersection_of: part_of UBERON:0002079 ! left atrium def: "An outflow tract of atrium that is part of a left atrium." [OBOL:automatic] [Term] id: UBERON:0005338 name: outflow tract aortic component xref: MA:0000101 ! outflow tract aortic component xref: VHOG:0001394 ! outflow tract aortic component xref: EHDAA2:0001353 ! outflow tract aortic component xref: EMAPA:17329 ! aortic component intersection_of: UBERON:0004145 ! outflow tract intersection_of: part_of UBERON:0000947 ! aorta def: "An outflow tract that is part of a aorta." [OBOL:automatic] [Term] id: UBERON:0005339 name: outflow tract pulmonary component xref: MA:0000102 ! outflow tract pulmonary component xref: EHDAA2:0001359 ! outflow tract pulmonary component xref: VHOG:0001395 ! outflow tract pulmonary component xref: EMAPA:17330 ! pulmonary component xref: EHDAA:4401 ! pulmonary component of outflow tract of heart is_a: UBERON:0004145 ! outflow tract [Term] id: UBERON:0004146 name: His-Purkinje system def: "The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles" [GO:0003164] synonym: "distal conduction system" EXACT [ZFA:0005071] synonym: "His-Purkinji network" EXACT [ZFA:0005071] synonym: "HPS" EXACT [ZFA:0005071] xref: ZFA:0005071 ! distal conduction system is_a: UBERON:0002350 ! conducting system of heart xref: TAO:0005071 ! distal conduction system [Term] id: UBERON:0004147 name: cardiac Purkinje fiber def: "The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle" [GO:0003165] synonym: "heart Purkinje fiber" RELATED [BTO:0001735] xref: BTO:0001735 ! cardiac Purkinje fiber xref: MESH:A07.541.409.683 ! purkinje fiber (also: UBERON:0002354 'purkinje fiber') is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0004146 ! His-Purkinje system [Term] id: UBERON:0001621 name: coronary artery def: "An artery that supplies the myocardium." [Wikipedia:Coronary_circulation#Coronary_anatomy] subset: uberon_slim synonym: "coronary arterial tree" EXACT [] xref: BTO:0000290 xref: FMA:49893 ! Coronary artery xref: galen:CoronaryArtery xref: MA:0002453 ! coronary artery xref: ncithesaurus:Coronary_Artery ! Coronary Artery xref: EFO:0002551 ! coronary artery xref: OpenCyc:Mx4rvoL56ZwpEbGdrcN5Y29ycA ! coronary artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/46/Gray492.png/200px-Gray492.png xref: EMAPA:19160 ! coronary artery of arterial system of cardiovascular system of organ system xref: EMAPA:25968 ! coronary artery of ascending aorta of arterial system of cardiovascular system of organ system xref: EV:0100383 ! coronary artery is_a: UBERON:0004573 ! systemic artery relationship: supplies UBERON:0002349 ! myocardium relationship: part_of UBERON:0000948 ! heart xref: SCTID:181294004 ! Entire coronary artery xref: VHOG:0001557 ! coronary artery xref: UMLS:C0205042 [Term] id: UBERON:0004148 name: cardiac vein def: "Vein of heart" [GOC:Obol] synonym: "coronary vein" RELATED [Wikipedia:Coronary_circulation] synonym: "heart vein" EXACT [OBOL:automatic] synonym: "vein of heart" EXACT [OBOL:automatic] synonym: "cardiac vein" EXACT [FMA:12846] xref: galen:CoronaryVein ! coronary vein xref: ncithesaurus:Coronary_Vein ! Coronary Vein xref: ncithesaurus:Cardiac_Vein ! cardiac vein xref: FMA:12846 ! Cardiac vein is_a: UBERON:0013140 {source="FMA"} ! systemic vein relationship: drains UBERON:0002349 ! myocardium relationship: part_of UBERON:0000948 ! heart xref: SCTID:277726009 ! Entire cardiac vein xref: EHDAA2:0004507 ! cardiac veins xref: UMLS:C0226654 xref: UMLS:C0226737 [Term] id: UBERON:0004149 name: ventriculo bulbo valve def: "A heart valve located between the ventricle and bulbus arteriosus." [GO:0003173] synonym: "bulboventricular valve" EXACT [ZFA:0001375] xref: ZFA:0001375 ! ventriculo bulbo valve is_a: UBERON:0000946 ! cardial valve relationship: develops_from UBERON:0002062 {source="ZFA"} ! endocardial cushion xref: TAO:0001375 ! ventriculo bulbo valve [Term] id: UBERON:0004150 name: coronary sinus valve def: "Vestigial cardiac valve which is continuous with the valve of the inferior vena cava[FMA]." [GO:0003178] comment: todo - development synonym: "valve of coronary sinus" EXACT [] synonym: "thebesian valve" EXACT [] synonym: "thebesius valve" EXACT [] xref: FMA:9242 ! valve of coronary sinus is_a: UBERON:0000946 ! cardial valve xref: SCTID:277723001 ! Entire valve of coronary sinus [Term] id: UBERON:0004151 ! cardiac chamber name: cardiac chamber def: "A cardiac chamber surrounds an enclosed cavity within the heart" [GO:0003205] comment: generic enough to cover FBbt:00003156 heart chamber but this is a cavity. GO defines it as the cavity. TODO - move subclasses. Note this also includes sinus venosus synonym: "heart chamber" EXACT [] synonym: "chamber of heart" EXACT [] xref: FMA:7095 ! cardiac chamber xref: OpenCyc:Mx4rmexpjPdAEduAAAAOpmP6tw ! heart chamber is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000948 ! heart xref: SCTID:276456008 ! Entire cardiac chamber [Term] id: UBERON:0004153 name: ventricular septum intermedium def: "Endocardial cushions project into the atrial canal, and, meeting in the middle line, unite to form the septum intermedium which divides the canal into two channels, the future right and left atrioventricular orifices[Gray's via WP]." [GO:0003282, Wikipedia:Septum_intermedium] synonym: "septum intermedium" EXACT [] is_a: UBERON:0002094 ! interventricular septum relationship: develops_from UBERON:0002062 {source="Wikipedia"} ! endocardial cushion xref: SCTID:361468003 ! Septum intermedium xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray467.png [Term] id: UBERON:0004154 name: septum primum def: "In the developing heart, the cavity of the primitive atrium becomes subdivided into right and left chambers by a septum, the septum primum, which grows downward into the cavity. The increasingly smaller gap below it (before it fuses with the endocardial cushion) is known as the ostium primum. The septum primum eventually fuses with the endocardial cushion, closing the ostium primum off completely. Meanwhile, perforations appear in the superior part of the septum primum, forming the ostium secundum. This will eventually form part of the fossa ovalis.." [GO:0003284, Wikipedia:Septum_primum] comment: AO notes: part_of IAS in EHDAA2 synonym: "interatrial septum primum" EXACT [EHDAA2:0001825] xref: EMAPA:17013 ! septum primum xref: VHOG:0000020 ! septum primum xref: FMA:63909 ! Septum primum xref: EHDAA:1900 ! septum primum xref: ncithesaurus:Septum_Primum ! Septum Primum xref: EHDAA2:0001825 ! interatrial septum primum is_a: UBERON:0002085 ! interatrial septum xref: SCTID:362017007 ! Entire septum primum xref: http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png property_value: external_definition "The first of the two membranous sheets which partially separate the two atria during embryonic development. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000020", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/interatrial+septum+primum", source="http://bgee.unil.ch/"} property_value: homology_notes "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {external_class="VHOG:0000020", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0225837 [Term] id: UBERON:0004155 name: septum secundum def: "." [GO:0003285, Wikipedia:Septum_secondum] comment: The septum secundum, semilunar in shape, grows downward from the upper wall of the atrium immediately to the right of the primary septum and ostium secundum. Shortly after birth it fuses with the septum primum, and consequently the foramen ovale is closed, but sometimes the fusion is incomplete and the upper part of the foramen remains patent. The limbus fossae ovalis denotes the free margin of the septum secundum. synonym: "interatrial septum secundum" EXACT [EHDAA2:0001827] xref: EMAPA:17864 ! septum secundum xref: VHOG:0000021 ! septum secundum xref: FMA:63910 ! Septum secundum xref: EHDAA:3406 ! septum secundum xref: ncithesaurus:Septum_Secundum ! Septum Secundum xref: EHDAA2:0001827 ! interatrial septum secundum is_a: UBERON:0002085 ! interatrial septum xref: SCTID:308850005 ! Entire septum secundum property_value: external_definition "The second of the two membranous sheets which partially separate the two atria during embryonic development. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000021", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/interatrial+septum+secundum", source="http://bgee.unil.ch/"} property_value: homology_notes "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {external_class="VHOG:0000021", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0225838 [Term] id: UBERON:0004157 name: atrial septum primum def: "." [GO:0003289] is_a: UBERON:0002085 ! interatrial septum [Term] id: UBERON:0004158 name: atrial septum secundum def: "." [GO:0003290] is_a: UBERON:0002085 ! interatrial septum [Term] id: UBERON:0004159 name: atrial septum intermedium def: "." [GO:0003291] is_a: UBERON:0002085 ! interatrial septum [Term] id: UBERON:0004160 ! proepicardium name: proepicardium def: "An outpouching of the septum transversum[GO]. An embryonic group of progenitor cells that forms near the venous pole of the heart and gives rise to the epicardium[Wiktionary]" [GO:0003342, http://en.wiktionary.org/wiki/proepicardium] is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0004161 ! septum transversum [Term] id: UBERON:0004161 name: septum transversum def: "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]." [Wikipedia:Septum_transversum, VHOG:0000019] comment: Note that in EHDAA2 this is divided into mesenchymal portion and hepatic diverticulum synonym: "transverse septum" EXACT [UBERON:cjm] xref: EMAPA:16318 ! septum transversum xref: VHOG:0000019 ! septum transversum xref: EHDAA:736 ! septum transversum xref: ncithesaurus:Septum_Transversum ! Septum Transversum xref: EHDAA2:0001829 ! septum transversum is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0002100 ! trunk relationship: located_in UBERON:0002323 ! coelemic cavity lumen xref: SCTID:308819008 ! Entire septum transversum property_value: external_definition "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000019", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/transverse+septum", source="http://bgee.unil.ch/"} property_value: homology_notes "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart (of other tetrapods) is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes) Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {external_class="VHOG:0000019", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231004 [Term] id: UBERON:0004162 name: pulmonary myocardium def: "The pulmonary myocardium is the myocardial tissue present in the pulmonary vein" [GO:0003350] is_a: UBERON:0002036 ! striated muscle tissue relationship: part_of UBERON:0002016 ! pulmonary vein relationship: part_of UBERON:0002349 ! myocardium [Term] id: UBERON:0004164 name: branchiomeric muscle def: "The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. Branchiomeric muscles of mammals correspond to the gill musculature of fish[GO]." [GO:0014707, Wikipedia:Branchiomeric_musculature] comment: Note: Kardong uses this term in a different way, including trapezius and mastoid groups synonym: "branchiomeric skeletal muscle" RELATED [GO:0014707] is_a: UBERON:0001134 ! skeletal muscle tissue relationship: develops_from UBERON:0010360 {source="PMID:21610022"} ! pharyngeal arch mesenchyme from head mesenchyme [Term] id: UBERON:0004166 name: superior reticular formation comment: check ZFA structures superior reticular formation medial column & tegmentum def: "." [GO:0021729, GO_REF:0000021] is_a: UBERON:0002275 ! reticular formation relationship: part_of UBERON:0002559 {source="GO"} ! medullary reticular formation [Term] id: UBERON:0009836 name: fronto-orbital gyrus synonym: "fronto-orbital gyrus" EXACT [NIF_GrossAnatomy:birnlex_1243] synonym: "orbitofrontal gyrus" EXACT [] synonym: "orbito-frontal gyrus" EXACT [] xref: NIF_GrossAnatomy:birnlex_1243 ! Fronto-orbital gyrus is_a: UBERON:0007193 {source="NIF"} ! orbital gyrus relationship: part_of UBERON:0004167 ! orbitofrontal cortex [Term] id: UBERON:0002799 name: fronto-orbital sulcus synonym: "fronto-orbital dimple" EXACT [FMA:83768] synonym: "orbito-frontal sulcus" EXACT [FMA:83768] synonym: "orbitofrontal sulcus" EXACT [BM:Tel-Cx-OFS] xref: FMA:83768 ! Fronto-orbital sulcus xref: NIF_GrossAnatomy:birnlex_1724 ! Fronto-orbital sulcus xref: BM:Tel-Cx-OFS ! orbitofrontal sulcus (also: UBERON:0002772 'olfactory sulcus') is_a: UBERON:0008334 {source="FMA"} ! subarachnoid sulcus relationship: part_of UBERON:0004167 ! orbitofrontal cortex [Term] id: UBERON:0004167 ! orbitofrontal cortex name: orbitofrontal cortex def: "the region of the cerebral cortex covering the basal surface of the frontal lobes; this region normally controls emotion and decision making" [MP:0004170, MGI:csmith, GO:0021769] synonym: "orbito-frontal cortex" EXACT [] synonym: "orbital frontal cortex" EXACT [DHB:OFC, NIF_GrossAnatomy:birnlex_1049] synonym: "fronto-orbital cortex" EXACT [] comment: note that this is a gyrus in FMA xref: FMA:242003 ! orbitofrontal cortex xref: EFO:0001990 ! orbitofrontal cortex xref: NIF_GrossAnatomy:birnlex_1049 ! Orbital frontal cortex is_a: UBERON:0002619 ! region of cerebral cortex relationship: part_of UBERON:0000349 {source="MP"} ! limbic system relationship: part_of UBERON:0001870 {source="GO", source="MP"} ! frontal lobe [Term] id: UBERON:0008882 name: spinal cord commissure def: "The nerve fiber tracts that span the midline of the spinal cord" [MP:0009694] intersection_of: UBERON:0001020 ! commissure intersection_of: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0007838 name: spinal cord white commissure synonym: "white commissure of spinal cord" EXACT [FMA:77033] xref: FMA:77033 ! white commissure of spinal cord is_a: UBERON:0001020 {source="FMA"} ! commissure relationship: part_of UBERON:0002240 ! spinal cord xref: SCTID:423957000 ! Structure of white commissure of spinal cord [Term] id: UBERON:0004677 name: spinal cord gray commissure def: "The gray commissure is a thin strip of gray matter that surrounds the central canal of the spinal cord and, along with the anterior white commissure, connects the two halves of the cord. It comprises lamina X in the Rexed classification." [Wikipedia:Gray_commissure] synonym: "spinal cord grey commissure" EXACT [OBOL:automatic] synonym: "spinal cord gray commissure" EXACT [NIF_GrossAnatomy:birnlex_2669] synonym: "gray commissure of spinal cord" EXACT [FMA:77036] xref: FMA:77036 ! gray commissure of spinal cord xref: NIF_GrossAnatomy:birnlex_2669 ! Spinal cord gray commissure xref: SCTID:362427009 ! Entire spinal cord gray commissures is_a: UBERON:0001020 {notes="check-me"} ! commissure is_a: UBERON:0002315 {source="FMA"} ! gray matter of spinal cord synonym: "commissura grisea anaterior medullae spinalis" RELATED LATIN [Wikipedia:Gray_commissure] synonym: "commissura grisea posterior medulla spinalis" RELATED LATIN [Wikipedia:Gray_commissure] xref: http://upload.wikimedia.org/wikipedia/commons/c/c0/Medulla_spinalis_-_Substantia_grisea_-_English.svg [Term] id: UBERON:0004170 ! spinal cord ventral commissure name: spinal cord ventral commissure def: "the band of nerve fibers which cross the midline of the spinal cord ventral to the central canal and posterior grey commissure[MP]. The anterior (or ventral) white commissure, also known as the alba anterior medullae spinalis, is a bundle of nerve fibers which cross the midline of the spinal cord just anterior to the gray commissure. A N4 fibers and C fibers carrying pain sensation in the spinothalamic tract contribute to this commissure, as do fibers of the anterior corticospinal tract, which carry motor signals from the primary motor cortex[WP]." [GO:0021965, MP:0009695, Wikipedia:Anterior_white_commissure] synonym: "anterior white commissure" EXACT [MP:0009695] synonym: "spinal cord anterior commissure" EXACT [MP:0009695] synonym: "ventral spinal commissure" EXACT [MP:0009695] synonym: "ventral white column" EXACT [MP:0009695] synonym: "white commissure" RELATED [MP:0009695] synonym: "anterior commissure" RELATED INCONSISTENT [MP:0009695] synonym: "anterior white commissure of spinal cord" EXACT [FMA:77035] synonym: "ventral white commissure of spinal cord" EXACT [FMA:77035] xref: FMA:77035 ! ventral white commissure of spinal cord is_a: UBERON:0007838 {source="FMA"} ! white commissure of spinal cord xref: ncithesaurus:White_Commissure ! White Commissure xref: SCTID:424149007 ! Structure of ventral white commissure of spinal cord synonym: "commissura alba anterior medullae spinalis, alba anterior medullae spinalis" RELATED LATIN [Wikipedia:Anterior_white_commissure] xref: http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray664.png xref: UMLS:C1520137 [Term] id: UBERON:0007840 name: spinal cord dorsal white commissure synonym: "posterior white commissure of spinal cord" EXACT [FMA:77034] synonym: "dorsal white commissure of spinal cord" EXACT [FMA:77034] xref: FMA:77034 ! dorsal white commissure of spinal cord is_a: UBERON:0007838 {source="FMA"} ! white commissure of spinal cord synonym: "commissura alba posterior medullae spinalis" EXACT LATIN [FMA:TA, FMA:77034] xref: SCTID:424400007 ! Structure of dorsal white commissure of spinal cord [Term] id: UBERON:0007834 name: lumbar spinal cord ventral commissure synonym: "lumbar spinal cord anterior commissure" EXACT [NIF_GrossAnatomy:birnlex_1326] xref: NIF_GrossAnatomy:birnlex_1326 ! Lumbar spinal cord ventral commissure intersection_of: UBERON:0004170 ! spinal cord ventral commissure intersection_of: part_of UBERON:0002792 ! lumbar spinal cord disjoint_from: UBERON:0005850 {source="NIF_GrossAnatomy"} ! lumbar spinal cord lateral column disjoint_from: UBERON:0005842 {source="NIF_GrossAnatomy"} ! lumbar spinal cord dorsal column disjoint_from: UBERON:0005855 {source="NIF_GrossAnatomy"} ! lumbar spinal cord ventral column def: "A spinal cord ventral commissure that is part of a lumbar spinal cord." [OBOL:automatic] [Term] id: UBERON:0007835 name: sacral spinal cord ventral commissure synonym: "sacral spinal cord anterior commissure" EXACT [NIF_GrossAnatomy:birnlex_1528] xref: NIF_GrossAnatomy:birnlex_1528 ! Sacral spinal cord ventral commissure intersection_of: UBERON:0004170 ! spinal cord ventral commissure intersection_of: part_of UBERON:0005843 ! sacral spinal cord disjoint_from: UBERON:0005840 {source="NIF_GrossAnatomy"} ! sacral spinal cord dorsal column disjoint_from: UBERON:0005853 {source="NIF_GrossAnatomy"} ! sacral spinal cord ventral column disjoint_from: UBERON:0005848 {source="NIF_GrossAnatomy"} ! sacral spinal cord lateral column def: "A spinal cord ventral commissure that is part of a sacral spinal cord." [OBOL:automatic] [Term] id: UBERON:0007836 name: cervical spinal cord ventral commissure synonym: "cervical spinal cord anterior commissure" EXACT [NIF_GrossAnatomy:birnlex_1552] xref: NIF_GrossAnatomy:birnlex_1552 ! Cervical spinal cord ventral commissure intersection_of: UBERON:0004170 ! spinal cord ventral commissure intersection_of: part_of UBERON:0002726 ! cervical spinal cord disjoint_from: UBERON:0005854 {source="NIF_GrossAnatomy"} ! cervical spinal cord ventral column disjoint_from: UBERON:0005849 {source="NIF_GrossAnatomy"} ! cervical spinal cord lateral column disjoint_from: UBERON:0005841 {source="NIF_GrossAnatomy"} ! cervical spinal cord dorsal column def: "A spinal cord ventral commissure that is part of a cervical spinal cord." [OBOL:automatic] [Term] id: UBERON:0007837 name: thoracic spinal cord ventral commissure synonym: "thoracic spinal cord anterior commissure" EXACT [NIF_GrossAnatomy:birnlex_1556] xref: NIF_GrossAnatomy:birnlex_1556 ! Thoracic spinal cord ventral commissure intersection_of: UBERON:0004170 ! spinal cord ventral commissure intersection_of: part_of UBERON:0003038 ! thoracic spinal cord disjoint_from: UBERON:0005847 {source="NIF_GrossAnatomy"} ! thoracic spinal cord lateral column disjoint_from: UBERON:0005839 {source="NIF_GrossAnatomy"} ! thoracic spinal cord dorsal column disjoint_from: UBERON:0005852 {source="NIF_GrossAnatomy"} ! thoracic spinal cord ventral column def: "A spinal cord ventral commissure that is part of a thoracic spinal cord." [OBOL:automatic] [Term] id: UBERON:0004171 name: trigeminothalamic tract def: "the trigeminothalamic tract is one of the major routes of nociceptive and temperature signaling from the face" [GO:0021974] xref: FMA:83852 ! Trigeminothalamic tract is_a: UBERON:0001018 ! axon tract relationship: has_function_in GO:0019233 {source="GO"} ! nociception [Term] id: UBERON:0004172 name: pons reticulospinal tract def: "axon tract that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord." [GO:0021975] is_a: UBERON:0001018 ! axon tract relationship: overlaps UBERON:0000988 ! pons relationship: overlaps UBERON:0002240 ! spinal cord xref: SCTID:362404001 ! Entire reticulospinal tract of pons [Term] id: UBERON:0004173 name: medulla reticulospinal tract def: "axon tract that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord[GO]." [GO:0021976] synonym: "medullary reticulospinal tract" EXACT [FMA:73989] is_a: UBERON:0001018 ! axon tract relationship: overlaps UBERON:0001896 ! medulla oblongata relationship: overlaps UBERON:0002240 ! spinal cord xref: FMA:73989 ! medullary reticulospinal tract [Term] id: UBERON:0004174 name: leg joint def: "Joint in the leg. For example the knee, which separates the leg tibia and femur" [GO:0035111] comment: Originally created for consistenct with GO, obsoleted when the GO class was obsoleted as the meaning was unclear synonym: "joint of leg" EXACT [OBOL:automatic] synonym: "joint of lower limb" RELATED [OBOL:automatic] is_obsolete: true consider: UBERON:0003657 [Term] id: UBERON:0003657 name: limb joint def: "Any joint that is part of a (free) limb." [UBERON:cjm] comment: Most limb joints are synovial, but a few such as the tibiofibular joints are syndesmoses subset: grouping_class synonym: "joint of limb" EXACT [] synonym: "joint of limb skeletal system" EXACT [OBOL:automatic] synonym: "skeletal limb joint" EXACT [GO:0036023] xref: MA:0000691 ! limb joint xref: galen:LimbJoint ! limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002101 ! limb xref: SCTID:312683002 ! Joint structure of limb [Term] id: UBERON:0011139 name: synovial limb joint def: "Any synovial joint that is part of a (free) limb." [UBERON:cjm] comment: Most limb joints are synovial, but a few such as the tibiofibular joints are syndesmoses. synonym: "synovial joint of free limb segment" EXACT [FMA:258776] is_a: UBERON:0003657 ! limb joint intersection_of: UBERON:0002217 ! synovial joint intersection_of: part_of UBERON:0002101 ! limb xref: FMA:258776 ! synovial joint of free limb segment [Term] id: UBERON:0004177 ! hemopoietic organ name: hemopoietic organ def: "Organ that is part of the hematopoietic system." [GOC:Obol] comment: note that the FMA class 'lymphoid organ' is a general anatomical term synonym: "hematopoeitic or lymphoid organ" NARROW [] synonym: "haematological system organ" EXACT [OBOL:automatic] synonym: "haemopoietic system organ" EXACT [OBOL:automatic] synonym: "hematopoietic system organ" EXACT [OBOL:automatic] synonym: "organ of haematological system" EXACT [OBOL:automatic] synonym: "organ of haemopoietic system" EXACT [OBOL:automatic] synonym: "organ of hematopoietic system" EXACT [OBOL:automatic] synonym: "organ of organa haemopoietica" EXACT [OBOL:automatic] synonym: "organa haemopoietica organ" EXACT [OBOL:automatic] synonym: "lymphoid organ" NARROW [BTO:0004605, FMA:7143] xref: BTO:0004605 ! lymphoid organ xref: FMA:7143 ! lymphoid organ intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002390 ! hematopoietic system subset: organ_slim xref: SCTID:361338006 ! Entire lymphoid organ [Term] id: UBERON:0004178 name: aorta smooth muscle tissue def: "A portion of smooth muscle tissue that is part of an aorta [Automatically generated definition]." [OBOL:automatic] synonym: "adult aorta involuntary muscle" EXACT [OBOL:automatic] synonym: "adult aorta non-striated muscle" EXACT [OBOL:automatic] synonym: "adult aorta smooth muscle" EXACT [OBOL:automatic] synonym: "adult aorta smooth muscle tissue" EXACT [OBOL:automatic] synonym: "aorta involuntary muscle" EXACT [OBOL:automatic] synonym: "aorta non-striated muscle" EXACT [OBOL:automatic] synonym: "aorta smooth muscle" EXACT [OBOL:automatic] synonym: "dorsal aorta involuntary muscle" EXACT [OBOL:automatic] synonym: "dorsal aorta non-striated muscle" EXACT [OBOL:automatic] synonym: "dorsal aorta smooth muscle" EXACT [OBOL:automatic] synonym: "dorsal aorta smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of adult aorta" EXACT [OBOL:automatic] synonym: "involuntary muscle of aorta" EXACT [OBOL:automatic] synonym: "involuntary muscle of dorsal aorta" EXACT [OBOL:automatic] synonym: "involuntary muscle of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "non-striated muscle of adult aorta" EXACT [OBOL:automatic] synonym: "non-striated muscle of aorta" EXACT [OBOL:automatic] synonym: "non-striated muscle of dorsal aorta" EXACT [OBOL:automatic] synonym: "non-striated muscle of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "smooth muscle of adult aorta" EXACT [OBOL:automatic] synonym: "smooth muscle of aorta" EXACT [OBOL:automatic] synonym: "smooth muscle of dorsal aorta" EXACT [OBOL:automatic] synonym: "smooth muscle of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of adult aorta" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of aorta" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of dorsal aorta" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "trunk of aortic tree involuntary muscle" EXACT [OBOL:automatic] synonym: "trunk of aortic tree non-striated muscle" EXACT [OBOL:automatic] synonym: "trunk of aortic tree smooth muscle" EXACT [OBOL:automatic] synonym: "trunk of aortic tree smooth muscle tissue" EXACT [OBOL:automatic] synonym: "aortic smooth muscle" EXACT [BTO:0001685] xref: ncithesaurus:Aorta_Smooth_Muscle_Tissue ! Aorta Smooth Muscle Tissue xref: MA:0000702 ! aorta smooth muscle xref: BTO:0001685 ! aortic smooth muscle xref: EFO:0002775 ! aorta smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000947 ! aorta xref: UMLS:C1706825 [Term] id: UBERON:0004180 name: mammary gland fat def: "The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts" [GO:0060611] synonym: "adipose tissue of lactiferous gland" EXACT [OBOL:automatic] synonym: "adipose tissue of mammary gland" EXACT [OBOL:automatic] synonym: "fat tissue of lactiferous gland" EXACT [OBOL:automatic] synonym: "fat tissue of lobe of breast" EXACT [OBOL:automatic] synonym: "fat tissue of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "fat tissue of mammary gland" EXACT [OBOL:automatic] synonym: "fatty tissue of lactiferous gland" EXACT [OBOL:automatic] synonym: "fatty tissue of lobe of breast" EXACT [OBOL:automatic] synonym: "fatty tissue of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "fatty tissue of mammary gland" EXACT [OBOL:automatic] synonym: "lactiferous gland adipose tissue" EXACT [OBOL:automatic] synonym: "lactiferous gland fat tissue" EXACT [OBOL:automatic] synonym: "lactiferous gland fatty tissue" EXACT [OBOL:automatic] synonym: "lobe of breast adipose tissue" EXACT [OBOL:automatic] synonym: "lobe of breast fat tissue" EXACT [OBOL:automatic] synonym: "lobe of breast fatty tissue" EXACT [OBOL:automatic] synonym: "lobe of mammary gland adipose tissue" EXACT [OBOL:automatic] synonym: "lobe of mammary gland fat tissue" EXACT [OBOL:automatic] synonym: "lobe of mammary gland fatty tissue" EXACT [OBOL:automatic] synonym: "mammary gland adipose tissue" EXACT [OBOL:automatic] synonym: "mammary gland fat tissue" EXACT [OBOL:automatic] synonym: "mammary gland fatty tissue" EXACT [OBOL:automatic] xref: MA:0002911 ! mammary gland fat intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0001911 ! lactiferous gland [Term] id: UBERON:0004183 name: labyrinthine layer blood vessel def: "The embryonic vessels grow through the layer to come in close contact with the maternal blood supply" [GO:0060716] synonym: "blood vessel of labyrinthine layer" EXACT [OBOL:automatic] synonym: "blood vessel of labyrinthine layer of placenta" EXACT [OBOL:automatic] synonym: "blood vessel of placenta labyrinth" EXACT [OBOL:automatic] synonym: "labyrinthine layer of placenta blood vessel" EXACT [OBOL:automatic] synonym: "placenta labyrinth blood vessel" EXACT [OBOL:automatic] intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003946 ! placenta labyrinth [Term] id: UBERON:0004184 name: prostate gland stroma alt_id: UBERON:0005084 def: "The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland" [GO:0060741] comment: TODO - check also FMA Stroma of glandular part of prostate synonym: "prostate stroma" EXACT [OBOL:automatic] synonym: "stroma of prostate" EXACT [OBOL:automatic] synonym: "stroma of prostate gland" EXACT [OBOL:automatic] synonym: "stroma of glandular part of prostate" NARROW [FMA:74349, OBOL:automatic] synonym: "prostatic stroma" EXACT [FMA:45719] xref: FMA:45719 ! Prostatic stroma xref: ncithesaurus:Prostatic_Stroma ! Prostatic Stroma xref: MA:0002912 ! prostate gland stroma intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0002367 ! prostate xref: UMLS:C1521760 [Term] id: UBERON:0004001 ! olfactory bulb layer name: olfactory bulb layer def: "." [MP:0009946] comment: TODO - check isa parentage synonym: "cytoarchitectural part of olfactory bulb" EXACT [NIF_GrossAnatomy:nlx_anat_20090402] xref: NIF_GrossAnatomy:nlx_anat_20090402 ! Cytoarchitectural part of olfactory bulb is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0002264 ! olfactory bulb [Term] id: UBERON:0004186 name: olfactory bulb mitral cell layer def: "The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer" [GO:0061034] comment: note that NIF divides this into main and accessory synonym: "mitral cell body layer" EXACT [NIF_GrossAnatomy:nlx_anat_100201] synonym: "olfactory bulb main mitral cell body layer" RELATED [NIF_GrossAnatomy:nlx_anat_100201] synonym: "mitral cell layer" EXACT [BTO:0001108] xref: MA:0000973 ! olfactory bulb mitral cell layer xref: NIF_GrossAnatomy:nlx_anat_100201 ! Mitral cell body layer xref: BTO:0001108 ! mitral cell layer is_a: UBERON:0004001 ! olfactory bulb layer [Term] id: UBERON:0009950 ! olfactory bulb plexiform layer name: olfactory bulb plexiform layer comment: check if the NIF class is actually a grouping class synonym: "plexiform layer" BROAD [NIF_GrossAnatomy:nlx_anat_20090405] is_a: UBERON:0004001 {source="NIF_GrossAnatomy"} ! olfactory bulb layer xref: NIF_GrossAnatomy:nlx_anat_20090405 ! Plexiform layer [Term] id: UBERON:0005379 name: olfactory bulb internal plexiform layer synonym: "internal plexiform layer" EXACT [BTO:0001320] xref: MA:0000972 ! olfactory bulb internal plexiform layer xref: BTO:0001320 ! internal plexiform layer [part_of: "olfactory bulb"] is_a: UBERON:0009950 ! olfactory bulb plexiform layer [Term] id: UBERON:0005376 name: olfactory bulb external plexiform layer def: "Cytoarchitectural part of the olfactory bulb, lying superior to the mitral cell layer and inferior to the glomerular layer. The EPL is mostly neuropil composed almost entirely of mitral and tulfted cell dendrites and granule cell dendrites and their synaptic inputs." [NIF_GrossAnatomy:nlx_anat_20090403] synonym: "external plexiform layer" BROAD [BTO:0001319] xref: MA:0000969 ! olfactory bulb external plexiform layer xref: NIF_GrossAnatomy:nlx_anat_20090403 ! External plexiform layer xref: BTO:0001319 ! external plexiform layer is_a: UBERON:0009950 ! olfactory bulb plexiform layer disjoint_from: UBERON:0001790 ! outer plexiform layer of retina [Term] id: UBERON:0005377 name: olfactory bulb glomerular layer def: "The glomerular layer is the most superficial layer, consisting of mitral cell dendritic arborizations (glomeruli), olfactory nerve fibers, and periglomerular cells. Periglomerular cells contact multiple mitral cell dendrites within the glomeruli and provide lateral inhibition of neighboring glomeruli while allowing excitation of a specific mitral cell dendritic tree. Each mitral cell is contacted by at least 1000 olfactory nerve fibers[BTO]. Portion of tissue which is located in between the primary olfactory fiber layer and the external cellular layer of the olfactory bulb[ZFA]." [BTO:0001317] subset: vertebrate_core synonym: "glomerular layer" BROAD [BTO:0001317, ZFA:0000357] synonym: "stratum glomerulosum bulbi olfactorii" EXACT [ZFA:0000357] xref: MA:0000970 ! olfactory bulb glomerular layer xref: BTO:0001317 ! glomerular layer xref: ZFA:0000357 ! glomerular layer xref: ABA:MOBgl ! Main olfactory bulb, glomerular layer is_a: UBERON:0004001 ! olfactory bulb layer xref: TAO:0000357 ! glomerular layer [Term] id: UBERON:0005378 name: olfactory bulb granule cell layer def: "The granule cell layer contains multiple small round neurons that lack axons. Long dendritic processes of the neurons reach the more superficial layers and inhibit mitral cells and tufted cells. Small distal processes make contacts with the exiting mitral cell axons." [BTO:0001327] synonym: "granule cell layer" BROAD [BTO:0001327] xref: MA:0000971 ! olfactory bulb granule cell layer xref: BTO:0001327 ! granule cell layer xref: NIF_GrossAnatomy:nlx_anat_20090404 ! Granule layer of main olfactory bulb is_a: UBERON:0004001 ! olfactory bulb layer [Term] id: UBERON:0005380 name: olfactory bulb subependymal zone xref: MA:0000974 ! olfactory bulb subependymal zone is_a: UBERON:0004001 ! olfactory bulb layer [Term] id: UBERON:0004189 name: glomerular endothelium def: "The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus" [GO:0072011] synonym: "endothelium of renal glomerulus" EXACT [OBOL:automatic] synonym: "renal glomerulus endothelium" EXACT [OBOL:automatic] xref: BTO:0004631 ! glomerular endothelium is_a: UBERON:0004188 ! glomerular epithelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000074 ! renal glomerulus relationship: part_of UBERON:0004190 ! glomerulus vasculature [Term] id: UBERON:0004190 name: glomerulus vasculature def: "The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus" [GO:0072012] synonym: "renal glomerulus vascular network" EXACT [OBOL:automatic] synonym: "renal glomerulus vasculature" EXACT [OBOL:automatic] synonym: "vascular network of renal glomerulus" EXACT [OBOL:automatic] synonym: "vasculature of renal glomerulus" EXACT [OBOL:automatic] intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000074 ! renal glomerulus [Term] id: UBERON:0004739 name: pronephric glomerulus alt_id: UBERON:0004191 def: "The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment." [GOC:mtg_kidney_jan10, PMID:10572058, PMID:15647339, PMID:9268568, XAO:0000318, GO:0072013] comment: a glomus differs from a glomerulus in that each vascular glomus services several tubules. ISBN10:0073040584 "Vertebrates\, Kardong". AO notes: GO treats glomus and pronephric glomerulus differently synonym: "glomerulus of pronephros" EXACT [] synonym: "glomus" NARROW [XAO:0000318] synonym: "corpuscle" RELATED [XAO:0000318] synonym: "glomera" RELATED PLURAL [XAO:0000318] xref: ZFA:0001557 ! pronephric glomerulus xref: VHOG:0001237 ! pronephric glomerulus xref: XAO:0000318 ! glomus xref: AAO:0011049 ! glomus xref: SCTID:360548001 ! Entire glomus xref: TAO:0001557 ! pronephric glomerulus intersection_of: UBERON:0000074 ! renal glomerulus intersection_of: part_of UBERON:0002120 ! pronephros relationship: develops_from UBERON:0007128 {source="XAO"} ! glomeral mesenchyme property_value: external_definition "Paired highly vascularized portion of the pronephros. Left and right glomeruli are fused at the midline. Begins to function between 40 and 48hpf. Drummond, 2000.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001557", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "pronephric glomera" RELATED [VHOG:0001237] synonym: "pronephric glomeruli" RELATED PLURAL [VHOG:0001237] synonym: "pronephric glomus" RELATED [VHOG:0001237] property_value: homology_notes "The teleost pronephros shares many essential features with the amphibian pronephros including its derivation from mesoderm associated with the coelom and the derivation of the glomerular blood supply from the medial dorsal aorta. However, unlike the pronephros of amphibians, which have an external glomus and tubules with nephrostomes open to the coelom, the mature teleost pronephros has no connection to the body cavity and instead functions as a closed system (reference 1); This variation in nephron types [with external glomeruli that open into the coelom and with internal glomeruli that do not connect with the coelom] and their pattern of distribution suggest an evolutionary sequence. Ancestral craniates probably had an external glomerulus and nephrostomes, as do the first few to develop in very primitive craniates. (...) The mechanism would become more efficient as the coelomic recess into which each glomerulus discharged became a part of the tubule, that is, grew around the glomerulus as a renal capsule. The glomerulus becomes internal. The nephrostomes were lost during subsequent evolution, leaving the type of renal tubule found in most vertebrates (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001237", ontology="VHOG", source="PMID:9806915 Drummond IA\, Majumdar A\, Hentschel H\, Elger M\, Solnica-Krezel L\, Schier AF\, Neuhauss SCF\, Stemple DL\, Zwartkruis F\, Rangini Z\, Driever W\, Fishman MC\, Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (1998)\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.636", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004194 name: long nephron def: "Long nephrons are associated with juxtamedullary glomeruli and extend to the inner medulla" [GO:0072029] synonym: "juxtamedullary nephron" RELATED [GO:0072029, http://sourceforge.net/tracker/?func=detail&aid=3031362&group_id=36855&atid=440764] is_a: UBERON:0001285 ! nephron xref: ncithesaurus:Juxtamedullary_Nephron ! Juxtamedullary Nephron xref: UMLS:C1517630 [Term] id: UBERON:0004195 name: short nephron def: "Short nephrons are associated with mid-cortical glomeruli, and have no short ascending limb, so the limb is situated in the outer medulla" [GO:0072030] is_a: UBERON:0001285 ! nephron [Term] id: UBERON:0004196 name: proximal convoluted tubule segment 1 alt_id: UBERON:0006432 def: "The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]." [GO:0072031, http://sourceforge.net/tracker/?func=detail&atid=440764&aid=3298740&group_id=36855] synonym: "S1" BROAD [GO:0072031] synonym: "S1 portion of renal tubule" EXACT [] synonym: "segment 1 of proximal tubule" EXACT [EMAPA:29657] synonym: "S1 portion of tubule" EXACT [] xref: MA:0002612 ! proximal tubule segment 1 xref: EMAPA:29657 ! segment 1 of proximal tubule is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001287 {source="GO"} ! proximal convoluted tubule relationship: has_function_in GO:0070295 {source="GO"} ! renal water absorption synonym: "proximal tubule segment 1" EXACT [MA:0002612] [Term] id: UBERON:0004197 name: proximal convoluted tubule segment 2 alt_id: UBERON:0006433 def: "The S2 portion of the tubule is involved in reabsorption of water and sodium chloride[GO]." [GO:0072032] synonym: "S2" BROAD [GO:0072032] synonym: "S2 portion of renal tubule" EXACT [] synonym: "segment 2 of proximal tubule" EXACT [EMAPA:29659] synonym: "S2 portion of tubule" EXACT [] xref: MA:0002613 ! proximal tubule segment 2 xref: EMAPA:29659 ! segment 2 of proximal tubule is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001287 {source="GO"} ! proximal convoluted tubule relationship: has_function_in GO:0070295 {source="GO"} ! renal water absorption synonym: "proximal tubule segment 2" EXACT [MA:0002613] [Term] id: UBERON:0010536 ! nephron progenitor name: nephron progenitor is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: part_of UBERON:0003918 {source="cjm"} ! kidney mesenchyme [Term] id: UBERON:0010537 name: mesonephric nephron progenitor def: "Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells." [ZFA:0005587] intersection_of: UBERON:0010536 ! nephron progenitor intersection_of: part_of UBERON:0000080 ! mesonephros xref: ZFA:0005587 ! nephron progenitor [Term] id: UBERON:0004209 ! renal vesicle name: renal vesicle def: "The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. " [GO:0072077] comment: Editor notes: note that this class includes both metanephric and mesonephric vesicles - ZFA and EHDAA2 associations are placed with these classes. TODO - make a more specific develops_from relationship - see UBERON:0005107 ! metanephric cap synonym: "stage I nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html, ZFA:0005586] is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle relationship: part_of UBERON:0001285 ! nephron relationship: induced_by UBERON:0000084 ! ureteric bud relationship: develops_from UBERON:0004208 ! nephrogenic mesenchyme [Term] id: UBERON:0005147 ! metanephric renal vesicle name: metanephric renal vesicle def: "The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0072283] synonym: "metanephric vesicle" EXACT [] xref: EHDAA2:0001245 ! nephric vesicles xref: EHDAA:9346 ! nephric vesicles xref: EMAPA:27678 ! renal vesicle of early tubule of metanephros of urinary system xref: EMAPA:27829 ! renal vesicle of early tubule of metanephros of urinary system intersection_of: UBERON:0004209 ! renal vesicle intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0005113 {source="EHDAA2"} ! metanephric cortex mesenchyme relationship: part_of UBERON:0005110 {is_inferred="true", source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005331 name: mesonephric renal vesicle def: "The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0061243] synonym: "mesonephric vesicle" EXACT [] xref: ZFA:0005586 ! renal vesicle intersection_of: UBERON:0004209 ! renal vesicle intersection_of: part_of UBERON:0000080 ! mesonephros relationship: develops_from UBERON:0010534 {source="ZFA"} ! mesonephric nephron progenitor xref: SCTID:361407006 ! Mesonephric vesicle relationship: part_of UBERON:0005322 {is_inferred="true", source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0010532 ! primitive nephron name: primitive nephron synonym: "developing nephron" BROAD [] synonym: "primitive nephron" BROAD [] is_a: UBERON:0003914 {source="EHDAA2-inferred"} ! epithelial tube is_a: UBERON:0001285 {source="ZFA-inferred"} ! nephron relationship: part_of UBERON:0003918 ! kidney mesenchyme relationship: develops_from UBERON:0004209 {source="EHDAA2"} ! renal vesicle [Term] id: UBERON:0010534 name: primitive mesonephric nephron synonym: "primitive mesonephric nephron" EXACT [] synonym: "developing mesonephric nephron" EXACT [ZFA:0005584] def: "Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells." [ZFA:0005587] intersection_of: UBERON:0010532 ! primitive nephron intersection_of: part_of UBERON:0000080 ! mesonephros xref: ZFA:0005584 ! developing mesonephric nephron [Term] id: UBERON:0010535 name: primitive metanephric nephron synonym: "primitive nephron" BROAD [EHDAA2:0001516] synonym: "primitive metanephric nephron" EXACT [] synonym: "developing metanephric nephron" EXACT [] intersection_of: UBERON:0010532 ! primitive nephron intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005113 {source="EHDAA2"} ! metanephric cortex mesenchyme xref: EHDAA2:0001516 ! primitive nephrons def: "A primitive nephron that is part of a metanephros." [OBOL:automatic] [Term] id: UBERON:0004198 name: comma-shaped body def: "The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron" [GO:0072049] xref: EMAPA:27681 ! comma-shaped body of early tubule of metanephros of urinary system xref: EMAPA:27835 ! comma-shaped body of early tubule of metanephros of urinary system xref: ZFA:0005588 ! comma-shaped body is_a: UBERON:0010532 {source="cjm"} ! primitive nephron relationship: part_of UBERON:0001285 ! nephron relationship: develops_from UBERON:0004209 {source="ZFA"} ! renal vesicle [Term] id: UBERON:0004199 name: S-shaped body def: "The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron" [GO:0072050] comment: TODO synonym: "stage II nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html] xref: EMAPA:27756 ! s-shaped body of early tubule of metanephros of urinary system xref: EMAPA:27853 ! s-shaped body of early tubule of metanephros of urinary system xref: ZFA:0005589 ! s-shaped body is_a: UBERON:0010532 {source="cjm"} ! primitive nephron relationship: develops_from UBERON:0004198 {source="GO"} ! comma-shaped body [Term] id: UBERON:0007653 ! capillary loop nephron name: capillary loop nephron def: "Developing nephron where the developing glomerular capsule has been invaded by a glomerular capillary loop called the glomerular tuft." [ZFIN:curator] comment: TODO synonym: "stage III nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Capillary_loop.html] synonym: "developing capillary loop stage nephron" EXACT [EMAPA:28506] xref: ZFA:0005590 ! capillary loop nephron xref: EMAPA:28506 ! developing capillary loop stage is_a: UBERON:0010532 {source="cjm"} ! primitive nephron relationship: develops_from UBERON:0004199 {source="ZFA"} ! S-shaped body [Term] id: UBERON:0007654 name: maturing nephron comment: TODO synonym: "stage IV nephron" RELATED [EMAPA:28485] xref: EMAPA:28485 ! maturing nephron is_a: UBERON:0010532 {source="cjm"} ! primitive nephron relationship: part_of UBERON:0001225 {source="EMAPA"} ! cortex of kidney relationship: develops_from UBERON:0007653 ! capillary loop nephron [Term] id: UBERON:0005322 name: mesonephric nephron def: "A nephron is the functional unit of the kidney[GO]." [GO:0061215] comment: TODO synonym: "stage IV nephron" RELATED [ZFA:0005592] xref: XAO:0000292 ! mesonephric nephron xref: ZFA:0005592 ! mesonephric nephron intersection_of: UBERON:0001285 ! nephron intersection_of: part_of UBERON:0000080 ! mesonephros relationship: develops_from UBERON:0005323 {source="XAO"} ! mesonephric mesenchyme xref: AAO:0010387 ! mesonephric nephron property_value: external_definition "The structure that is the basic functional unit of the kidney.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010387", date_retrieved="2012-06-20", source="PMID:9268568"} [Term] id: UBERON:0005146 name: metanephric nephron tubule alt_id: UBERON:0005128 alt_id: UBERON:0005152 def: "A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]." [GO:0072282] intersection_of: UBERON:0001231 ! nephron tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0003220 {source="ISBN:9780878932504"} ! metanephric mesenchyme relationship: part_of UBERON:0005110 {is_inferred="true", source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005148 name: metanephric S-shaped body def: "The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]." [GO:0072284] intersection_of: UBERON:0004199 ! S-shaped body intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005322 {notes="todo - automate"} ! mesonephric nephron [Term] id: UBERON:0004201 name: kidney outer medulla inner stripe def: "The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thick and thin portions of nephron tubules" [GO:0072057] synonym: "inner stripe" EXACT [GO:0072057] synonym: "outer medulla inner stripe" EXACT [MA:0002626] synonym: "inner stripe of outer medulla" EXACT [EMAPA:29675] synonym: "inner stripe of medulla of kidney" EXACT [FMA:76663] synonym: "inner stripe of renal medulla" EXACT [FMA:76663] xref: FMA:76663 ! Inner stripe of medulla of kidney xref: EMAPA:29675 ! inner stripe of outer medulla xref: MA:0002626 ! outer medulla inner stripe is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001293 ! outer medulla of kidney synonym: "stria interna medullae renalis" EXACT LATIN [FMA:TA, FMA:76663] [Term] id: UBERON:0004202 name: kidney outer medulla outer stripe def: "The outer stripe is the region of the kidney that lies distal to the line of termination of the straight renal tubules" [GO:0072058] synonym: "outer stripe" EXACT [GO:0072058] synonym: "outer medulla outer stripe" EXACT [MA:0002629] synonym: "outer stripe of outer medulla" EXACT [EMAPA:29663] synonym: "outer stripe of medulla of kidney" EXACT [FMA:76662] synonym: "outer stripe of renal medulla" EXACT [FMA:76662] xref: FMA:76662 ! Outer stripe of medulla of kidney xref: EMAPA:29663 ! outer stripe of outer medulla xref: MA:0002629 ! outer medulla outer stripe is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001293 ! outer medulla of kidney synonym: "stria externa medullae renalis" EXACT LATIN [FMA:TA, FMA:76662] [Term] id: UBERON:0004203 name: cortical collecting duct def: "The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex" [GO:0072059] xref: EMAPA:28130 ! cortical collecting duct xref: BTO:0002643 ! cortical collecting duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule intersection_of: part_of UBERON:0001225 ! cortex of kidney [Term] id: UBERON:0004204 name: outer medullary collecting duct def: "The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla" [GO:0072060] xref: EMAPA:28346 ! outer medullary collecting duct is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: UBERON:0004205 name: inner medullary collecting duct def: "The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla" [GO:0072061] xref: EMAPA:28370 ! inner medullary collecting duct xref: BTO:0004544 ! inner medullary collecting duct is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: UBERON:0004206 name: long descending thin limb bend def: "The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment" [GO:0072065] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001289 ! descending limb of loop of Henle [Term] id: UBERON:0004207 name: prebend segment def: "The prebend segment is a part of the descending thin limb that lies before the bend and exhibits robust sodium chloride reabsorption" [GO:0072066] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001289 ! descending limb of loop of Henle relationship: part_of UBERON:0005096 {source="GO"} ! descending thin limb [Term] id: UBERON:0004211 name: nephron epithelium def: "The nephron epithelium is a tissue that covers the surface of a nephron" [GO:0072088] synonym: "epithelial tissue of nephron" EXACT [OBOL:automatic] synonym: "epithelium of nephron" EXACT [OBOL:automatic] synonym: "nephron epithelial tissue" EXACT [OBOL:automatic] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001285 ! nephron [Term] id: UBERON:0004214 name: upper leg nerve def: "A nerve that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "Proximal segment of free lower limb nerve" EXACT [OBOL:automatic] synonym: "hind limb stylopod nerve" EXACT [OBOL:automatic] synonym: "hindlimb stylopod nerve" EXACT [OBOL:automatic] synonym: "inferior member stylopod nerve" EXACT [OBOL:automatic] synonym: "lower extremity stylopod nerve" EXACT [OBOL:automatic] synonym: "nerve of Proximal segment of free lower limb" EXACT [OBOL:automatic] synonym: "nerve of hind limb stylopod" EXACT [OBOL:automatic] synonym: "nerve of hindlimb stylopod" EXACT [OBOL:automatic] synonym: "nerve of inferior member stylopod" EXACT [OBOL:automatic] synonym: "nerve of lower extremity stylopod" EXACT [OBOL:automatic] synonym: "nerve of stylopod of hind limb" EXACT [OBOL:automatic] synonym: "nerve of stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "nerve of stylopod of inferior member" EXACT [OBOL:automatic] synonym: "nerve of stylopod of lower extremity" EXACT [OBOL:automatic] synonym: "nerve of stylopod of lower limb" EXACT [OBOL:automatic] synonym: "nerve of thigh" EXACT [OBOL:automatic] synonym: "nerve of upper leg" EXACT [OBOL:automatic] synonym: "stylopod of hind limb nerve" EXACT [OBOL:automatic] synonym: "stylopod of hindlimb nerve" EXACT [OBOL:automatic] synonym: "stylopod of inferior member nerve" EXACT [OBOL:automatic] synonym: "stylopod of lower extremity nerve" EXACT [OBOL:automatic] synonym: "stylopod of lower limb nerve" EXACT [OBOL:automatic] synonym: "thigh nerve" EXACT [OBOL:automatic] xref: MA:0000685 ! upper leg nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004215 name: back nerve def: "A nerve that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of back" EXACT [OBOL:automatic] xref: MA:0000497 ! back nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004216 name: lower arm nerve def: "A nerve that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "antebrachial region nerve" EXACT [OBOL:automatic] synonym: "arm middle limb segment nerve" EXACT [OBOL:automatic] synonym: "arm zeugopod nerve" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment nerve" EXACT [OBOL:automatic] synonym: "brachial region zeugopod nerve" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "lower segment of arm nerve" EXACT [OBOL:automatic] synonym: "middle limb segment of arm nerve" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region nerve" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "nerve of antebrachial region" EXACT [OBOL:automatic] synonym: "nerve of arm middle limb segment" EXACT [OBOL:automatic] synonym: "nerve of arm zeugopod" EXACT [OBOL:automatic] synonym: "nerve of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "nerve of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "nerve of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of lower arm" EXACT [OBOL:automatic] synonym: "nerve of lower segment of arm" EXACT [OBOL:automatic] synonym: "nerve of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "nerve of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "nerve of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "nerve of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of arm" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment nerve" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod nerve" EXACT [OBOL:automatic] synonym: "zeugopod of arm nerve" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region nerve" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb nerve" EXACT [OBOL:automatic] xref: MA:0000601 ! lower arm nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002386 ! lower segment of arm [Term] id: UBERON:0004217 name: upper arm nerve def: "A nerve that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "Proximal segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "arm stylopod nerve" EXACT [OBOL:automatic] synonym: "brachial region stylopod nerve" EXACT [OBOL:automatic] synonym: "nerve of Proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of arm stylopod" EXACT [OBOL:automatic] synonym: "nerve of brachial region stylopod" EXACT [OBOL:automatic] synonym: "nerve of proximal segment of free upper limb stylopod" EXACT [OBOL:automatic] synonym: "nerve of stylopod of arm" EXACT [OBOL:automatic] synonym: "nerve of stylopod of brachial region" EXACT [OBOL:automatic] synonym: "nerve of stylopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of upper arm" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb stylopod nerve" EXACT [OBOL:automatic] synonym: "stylopod of arm nerve" EXACT [OBOL:automatic] synonym: "stylopod of brachial region nerve" EXACT [OBOL:automatic] synonym: "stylopod of proximal segment of free upper limb nerve" EXACT [OBOL:automatic] xref: MA:0000607 ! upper arm nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0003822 ! upper arm [Term] id: UBERON:0004218 name: lower leg nerve def: "A nerve that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb middle limb segment nerve" EXACT [OBOL:automatic] synonym: "hind limb zeugopod nerve" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment nerve" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod nerve" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment nerve" EXACT [OBOL:automatic] synonym: "inferior member zeugopod nerve" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb nerve" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment nerve" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod nerve" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb nerve" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb nerve" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member nerve" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity nerve" EXACT [OBOL:automatic] synonym: "nerve of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "nerve of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "nerve of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "nerve of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "nerve of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "nerve of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "nerve of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "nerve of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "nerve of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "nerve of lower leg" EXACT [OBOL:automatic] synonym: "nerve of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "nerve of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "nerve of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "nerve of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of leg" EXACT [OBOL:automatic] synonym: "nerve of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb nerve" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb nerve" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member nerve" EXACT [OBOL:automatic] synonym: "zeugopod of leg nerve" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity nerve" EXACT [OBOL:automatic] xref: MA:0000679 ! lower leg nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0003823 ! lower leg [Term] id: UBERON:0004219 name: urethra smooth muscle def: "A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of urethra" EXACT [OBOL:automatic] synonym: "non-striated muscle of urethra" EXACT [OBOL:automatic] synonym: "smooth muscle of urethra" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra involuntary muscle" EXACT [OBOL:automatic] synonym: "urethra non-striated muscle" EXACT [OBOL:automatic] synonym: "urethra smooth muscle tissue" EXACT [OBOL:automatic] synonym: "urethral smooth muscle" RELATED [MA:0001691] xref: MA:0001691 ! urethra smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0004223 name: vagina smooth muscle def: "A portion of smooth muscle tissue that is part of a vagina [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of vagina" EXACT [OBOL:automatic] synonym: "non-striated muscle of vagina" EXACT [OBOL:automatic] synonym: "smooth muscle of vagina" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of vagina" EXACT [OBOL:automatic] synonym: "vagina involuntary muscle" EXACT [OBOL:automatic] synonym: "vagina non-striated muscle" EXACT [OBOL:automatic] synonym: "vagina smooth muscle tissue" EXACT [OBOL:automatic] synonym: "vagina smooth muscle" RELATED [BTO:0004999] synonym: "vaginal smooth muscle" EXACT [BTO:0004999] xref: MA:0001733 ! vagina smooth muscle xref: BTO:0004999 ! vaginal smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000996 ! vagina [Term] id: UBERON:0004224 name: vas deferens smooth muscle def: "A portion of smooth muscle tissue that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] comment: todo - check MA and FMA classes mean the same thing synonym: "muscle layer of deferent duct" EXACT [FMA:19239] synonym: "muscle layer of ductus deferens" EXACT [FMA:19239] synonym: "muscle layer of vas deferens" EXACT [FMA:19239] synonym: "muscular coat of ductus deferens" EXACT [FMA:19239] synonym: "muscular layer of ductus deferens" EXACT [FMA:19239] synonym: "muscularis of vas deferens" EXACT [FMA:19239] synonym: "tunica muscularis (Ductus deferens)" EXACT [FMA:19239] xref: FMA:19239 ! Muscle layer of deferent duct xref: EMAPA:29270 ! muscle layer of ductus deferens xref: MA:0001750 ! vas deferens smooth muscle is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0001000 ! vas deferens synonym: "tunica muscularis ductus deferentis" EXACT LATIN [FMA:TA, FMA:19239] xref: SCTID:299705008 ! Entire muscularis of vas deferens [Term] id: UBERON:0004225 name: respiratory system smooth muscle def: "A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius involuntary muscle" EXACT [OBOL:automatic] synonym: "apparatus respiratorius non-striated muscle" EXACT [OBOL:automatic] synonym: "apparatus respiratorius smooth muscle" EXACT [OBOL:automatic] synonym: "apparatus respiratorius smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "involuntary muscle of respiratory system" EXACT [OBOL:automatic] synonym: "non-striated muscle of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "non-striated muscle of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system involuntary muscle" EXACT [OBOL:automatic] synonym: "respiratory system non-striated muscle" EXACT [OBOL:automatic] synonym: "respiratory system smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "smooth muscle of respiratory system" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory smooth muscle" EXACT [BTO:0001660] synonym: "airway smooth muscle" RELATED [BTO:0001660] xref: MA:0001830 ! respiratory system smooth muscle xref: BTO:0001660 ! respiratory smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0004226 name: gastrointestinal system smooth muscle def: "A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "digestive system involuntary muscle" EXACT [OBOL:automatic] synonym: "digestive system non-striated muscle" EXACT [OBOL:automatic] synonym: "digestive system smooth muscle" EXACT [OBOL:automatic] synonym: "digestive system smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gastrointestinal system involuntary muscle" EXACT [OBOL:automatic] synonym: "gastrointestinal system non-striated muscle" EXACT [OBOL:automatic] synonym: "gastrointestinal system smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of digestive system" EXACT [OBOL:automatic] synonym: "involuntary muscle of gastrointestinal system" EXACT [OBOL:automatic] synonym: "non-striated muscle of digestive system" EXACT [OBOL:automatic] synonym: "non-striated muscle of gastrointestinal system" EXACT [OBOL:automatic] synonym: "smooth muscle of digestive system" EXACT [OBOL:automatic] synonym: "smooth muscle of gastrointestinal system" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of digestive system" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gastrointestinal system" EXACT [OBOL:automatic] xref: MA:0001523 ! gastrointestinal system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005409 ! gastrointestinal system [Term] id: UBERON:0004227 name: kidney pelvis smooth muscle def: "A portion of smooth muscle tissue that is part of a renal pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of kidney pelvis" EXACT [OBOL:automatic] synonym: "involuntary muscle of pelvis of ureter" EXACT [OBOL:automatic] synonym: "involuntary muscle of renal pelvis" EXACT [OBOL:automatic] synonym: "kidney pelvis involuntary muscle" EXACT [OBOL:automatic] synonym: "kidney pelvis non-striated muscle" EXACT [OBOL:automatic] synonym: "kidney pelvis smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of kidney pelvis" EXACT [OBOL:automatic] synonym: "non-striated muscle of pelvis of ureter" EXACT [OBOL:automatic] synonym: "non-striated muscle of renal pelvis" EXACT [OBOL:automatic] synonym: "pelvis of ureter involuntary muscle" EXACT [OBOL:automatic] synonym: "pelvis of ureter non-striated muscle" EXACT [OBOL:automatic] synonym: "pelvis of ureter smooth muscle" EXACT [OBOL:automatic] synonym: "pelvis of ureter smooth muscle tissue" EXACT [OBOL:automatic] synonym: "renal pelvis involuntary muscle" EXACT [OBOL:automatic] synonym: "renal pelvis non-striated muscle" EXACT [OBOL:automatic] synonym: "renal pelvis smooth muscle" EXACT [OBOL:automatic] synonym: "renal pelvis smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of kidney pelvis" EXACT [OBOL:automatic] synonym: "smooth muscle of pelvis of ureter" EXACT [OBOL:automatic] synonym: "smooth muscle of renal pelvis" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of kidney pelvis" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of pelvis of ureter" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of renal pelvis" EXACT [OBOL:automatic] xref: MA:0002631 ! kidney pelvis smooth muscle xref: FMA:262022 ! Smooth muscle tissue of renal pelvis intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001224 ! renal pelvis [Term] id: UBERON:0004229 name: urinary bladder trigone smooth muscle def: "A portion of smooth muscle tissue that is part of a trigone of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "Lieutaud's trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "Lieutaud's trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "Lieutaud's trigone smooth muscle" EXACT [OBOL:automatic] synonym: "Lieutaud's trigone smooth muscle tissue" EXACT [OBOL:automatic] synonym: "deep trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "deep trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "deep trigone smooth muscle" EXACT [OBOL:automatic] synonym: "deep trigone smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "involuntary muscle of deep trigone" EXACT [OBOL:automatic] synonym: "involuntary muscle of trigone of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "involuntary muscle of vesical trigone" EXACT [OBOL:automatic] synonym: "non-striated muscle of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "non-striated muscle of deep trigone" EXACT [OBOL:automatic] synonym: "non-striated muscle of trigone of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "non-striated muscle of vesical trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of deep trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of trigone of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "smooth muscle of vesical trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of Lieutaud's trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of deep trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of trigone of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of vesical trigone" EXACT [OBOL:automatic] synonym: "trigone of bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "trigone of bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "trigone of bladder smooth muscle" EXACT [OBOL:automatic] synonym: "trigone of bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder smooth muscle" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "urinary bladder trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder trigone smooth muscle tissue" EXACT [OBOL:automatic] synonym: "vesical trigone involuntary muscle" EXACT [OBOL:automatic] synonym: "vesical trigone non-striated muscle" EXACT [OBOL:automatic] synonym: "vesical trigone smooth muscle" EXACT [OBOL:automatic] synonym: "vesical trigone smooth muscle tissue" EXACT [OBOL:automatic] xref: MA:0001700 ! urinary bladder trigone smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001257 ! trigone of urinary bladder synonym: "urinary bladder trigone muscle" EXACT [MA:0001700] [Term] id: UBERON:0004230 name: urinary bladder neck smooth muscle def: "A portion of smooth muscle tissue that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck involuntary muscle" EXACT [OBOL:automatic] synonym: "bladder neck non-striated muscle" EXACT [OBOL:automatic] synonym: "bladder neck smooth muscle" EXACT [OBOL:automatic] synonym: "bladder neck smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bladder neck" EXACT [OBOL:automatic] synonym: "involuntary muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "involuntary muscle of vesical neck" EXACT [OBOL:automatic] synonym: "neck of bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "neck of bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "neck of bladder smooth muscle" EXACT [OBOL:automatic] synonym: "neck of bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "neck of urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder smooth muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of bladder neck" EXACT [OBOL:automatic] synonym: "non-striated muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "non-striated muscle of vesical neck" EXACT [OBOL:automatic] synonym: "smooth muscle of bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle of vesical neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of neck of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of vesical neck" EXACT [OBOL:automatic] synonym: "urinary bladder neck involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder neck non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder neck smooth muscle tissue" EXACT [OBOL:automatic] synonym: "vesical neck involuntary muscle" EXACT [OBOL:automatic] synonym: "vesical neck non-striated muscle" EXACT [OBOL:automatic] synonym: "vesical neck smooth muscle" EXACT [OBOL:automatic] synonym: "vesical neck smooth muscle tissue" EXACT [OBOL:automatic] synonym: "trigonal muscle of urinary bladder" EXACT [FMA:67990] synonym: "urinary bladder neck muscle" EXACT [MA:0001699] xref: MA:0001699 ! urinary bladder neck smooth muscle xref: FMA:67990 ! trigonal muscle of urinary bladder intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001258 ! neck of urinary bladder [Term] id: UBERON:0004231 name: anal region smooth muscle def: "A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]." [OBOL:automatic] synonym: "anal part of perineum involuntary muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum non-striated muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum smooth muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum smooth muscle tissue" EXACT [OBOL:automatic] synonym: "anal region involuntary muscle" EXACT [OBOL:automatic] synonym: "anal region non-striated muscle" EXACT [OBOL:automatic] synonym: "anal region smooth muscle tissue" EXACT [OBOL:automatic] synonym: "anal triangle involuntary muscle" EXACT [OBOL:automatic] synonym: "anal triangle non-striated muscle" EXACT [OBOL:automatic] synonym: "anal triangle smooth muscle" EXACT [OBOL:automatic] synonym: "anal triangle smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal region" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal triangle" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal region" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal triangle" EXACT [OBOL:automatic] synonym: "smooth muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "smooth muscle of anal region" EXACT [OBOL:automatic] synonym: "smooth muscle of anal triangle" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal part of perineum" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal region" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal triangle" EXACT [OBOL:automatic] xref: MA:0001532 ! anal region smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0004232 name: lymphatic vessel smooth muscle def: "A portion of smooth muscle tissue that is part of a lymphatic vessel [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of lymph vessel" EXACT [OBOL:automatic] synonym: "involuntary muscle of lymphatic vessel" EXACT [OBOL:automatic] synonym: "lymph vessel involuntary muscle" EXACT [OBOL:automatic] synonym: "lymph vessel non-striated muscle" EXACT [OBOL:automatic] synonym: "lymph vessel smooth muscle" EXACT [OBOL:automatic] synonym: "lymph vessel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "lymphatic vessel involuntary muscle" EXACT [OBOL:automatic] synonym: "lymphatic vessel non-striated muscle" EXACT [OBOL:automatic] synonym: "lymphatic vessel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of lymph vessel" EXACT [OBOL:automatic] synonym: "non-striated muscle of lymphatic vessel" EXACT [OBOL:automatic] synonym: "smooth muscle of lymph vessel" EXACT [OBOL:automatic] synonym: "smooth muscle of lymphatic vessel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lymph vessel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lymphatic vessel" EXACT [OBOL:automatic] xref: MA:0000751 ! lymphatic vessel smooth muscle xref: ncithesaurus:Lymphatic_Vessel_Smooth_Muscle_Tissue ! Lymphatic Vessel Smooth Muscle Tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001473 ! lymphatic vessel xref: UMLS:C1708791 [Term] id: UBERON:0004233 name: lower respiratory tract smooth muscle def: "A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract involuntary muscle" EXACT [OBOL:automatic] synonym: "lower respiratory tract non-striated muscle" EXACT [OBOL:automatic] synonym: "lower respiratory tract smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "smooth muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lower respiratory tract" EXACT [OBOL:automatic] xref: MA:0002410 ! lower respiratory tract smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001558 ! lower respiratory tract [Term] id: UBERON:0004234 name: iris smooth muscle def: "A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of iris" EXACT [OBOL:automatic] synonym: "iris involuntary muscle" EXACT [OBOL:automatic] synonym: "iris non-striated muscle" EXACT [OBOL:automatic] synonym: "iris smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of iris" EXACT [OBOL:automatic] synonym: "smooth muscle of iris" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of iris" EXACT [OBOL:automatic] xref: MA:0001270 ! iris smooth muscle xref: BTO:0000655 ! iris smooth muscle is_a: UBERON:0001606 ! muscle of iris intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001769 ! iris [Term] id: UBERON:0004235 name: mammary gland smooth muscle def: "A portion of smooth muscle tissue that is part of a lactiferous gland [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of lactiferous gland" EXACT [OBOL:automatic] synonym: "involuntary muscle of lobe of breast" EXACT [OBOL:automatic] synonym: "involuntary muscle of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "involuntary muscle of mammary gland" EXACT [OBOL:automatic] synonym: "lactiferous gland involuntary muscle" EXACT [OBOL:automatic] synonym: "lactiferous gland non-striated muscle" EXACT [OBOL:automatic] synonym: "lactiferous gland smooth muscle" EXACT [OBOL:automatic] synonym: "lactiferous gland smooth muscle tissue" EXACT [OBOL:automatic] synonym: "lobe of breast involuntary muscle" EXACT [OBOL:automatic] synonym: "lobe of breast non-striated muscle" EXACT [OBOL:automatic] synonym: "lobe of breast smooth muscle" EXACT [OBOL:automatic] synonym: "lobe of breast smooth muscle tissue" EXACT [OBOL:automatic] synonym: "lobe of mammary gland involuntary muscle" EXACT [OBOL:automatic] synonym: "lobe of mammary gland non-striated muscle" EXACT [OBOL:automatic] synonym: "lobe of mammary gland smooth muscle" EXACT [OBOL:automatic] synonym: "lobe of mammary gland smooth muscle tissue" EXACT [OBOL:automatic] synonym: "mammary gland involuntary muscle" EXACT [OBOL:automatic] synonym: "mammary gland non-striated muscle" EXACT [OBOL:automatic] synonym: "mammary gland smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of lactiferous gland" EXACT [OBOL:automatic] synonym: "non-striated muscle of lobe of breast" EXACT [OBOL:automatic] synonym: "non-striated muscle of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "non-striated muscle of mammary gland" EXACT [OBOL:automatic] synonym: "smooth muscle of lactiferous gland" EXACT [OBOL:automatic] synonym: "smooth muscle of lobe of breast" EXACT [OBOL:automatic] synonym: "smooth muscle of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "smooth muscle of mammary gland" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lactiferous gland" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lobe of breast" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lobe of mammary gland" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of mammary gland" EXACT [OBOL:automatic] xref: MA:0000795 ! mammary gland smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001911 ! lactiferous gland [Term] id: UBERON:0004236 name: arteriole smooth muscle def: "A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]." [OBOL:automatic] xref: MA:0000706 ! arteriole smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001980 ! arteriole [Term] id: UBERON:0004238 name: spleen smooth muscle def: "A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of spleen" EXACT [OBOL:automatic] synonym: "non-striated muscle of spleen" EXACT [OBOL:automatic] synonym: "smooth muscle of spleen" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of spleen" EXACT [OBOL:automatic] synonym: "spleen involuntary muscle" EXACT [OBOL:automatic] synonym: "spleen non-striated muscle" EXACT [OBOL:automatic] synonym: "spleen smooth muscle tissue" EXACT [OBOL:automatic] xref: MA:0000757 ! spleen smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002106 ! spleen [Term] id: UBERON:0004240 name: gall bladder smooth muscle def: "A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "gall bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "gall bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "gall bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gallbladder involuntary muscle" EXACT [OBOL:automatic] synonym: "gallbladder non-striated muscle" EXACT [OBOL:automatic] synonym: "gallbladder smooth muscle" EXACT [OBOL:automatic] synonym: "gallbladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of gall bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of gallbladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of gall bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of gallbladder" EXACT [OBOL:automatic] synonym: "smooth muscle of gall bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of gallbladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gall bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gallbladder" EXACT [OBOL:automatic] synonym: "biliary smooth muscle" RELATED [MA:0001635] xref: MA:0001635 ! gall bladder smooth muscle xref: ncithesaurus:Gallbladder_Smooth_Muscle_Tissue ! Gallbladder Smooth Muscle Tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002110 ! gallbladder xref: UMLS:C1708179 [Term] id: UBERON:0004241 name: main bronchus smooth muscle def: "A portion of smooth muscle tissue that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchus principalis involuntary muscle" EXACT [OBOL:automatic] synonym: "bronchus principalis non-striated muscle" EXACT [OBOL:automatic] synonym: "bronchus principalis smooth muscle" EXACT [OBOL:automatic] synonym: "bronchus principalis smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bronchus principalis" EXACT [OBOL:automatic] synonym: "involuntary muscle of main bronchus" EXACT [OBOL:automatic] synonym: "involuntary muscle of primary bronchus" EXACT [OBOL:automatic] synonym: "involuntary muscle of principal bronchus" EXACT [OBOL:automatic] synonym: "main bronchus involuntary muscle" EXACT [OBOL:automatic] synonym: "main bronchus non-striated muscle" EXACT [OBOL:automatic] synonym: "main bronchus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of bronchus principalis" EXACT [OBOL:automatic] synonym: "non-striated muscle of main bronchus" EXACT [OBOL:automatic] synonym: "non-striated muscle of primary bronchus" EXACT [OBOL:automatic] synonym: "non-striated muscle of principal bronchus" EXACT [OBOL:automatic] synonym: "primary bronchus involuntary muscle" EXACT [OBOL:automatic] synonym: "primary bronchus non-striated muscle" EXACT [OBOL:automatic] synonym: "primary bronchus smooth muscle" EXACT [OBOL:automatic] synonym: "primary bronchus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "principal bronchus involuntary muscle" EXACT [OBOL:automatic] synonym: "principal bronchus non-striated muscle" EXACT [OBOL:automatic] synonym: "principal bronchus smooth muscle" EXACT [OBOL:automatic] synonym: "principal bronchus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of bronchus principalis" EXACT [OBOL:automatic] synonym: "smooth muscle of main bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle of primary bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle of principal bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bronchus principalis" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of main bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of primary bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of principal bronchus" EXACT [OBOL:automatic] xref: MA:0001848 ! main bronchus smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002182 ! main bronchus [Term] id: UBERON:0004242 name: bronchus smooth muscle def: "A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi involuntary muscle" EXACT [OBOL:automatic] synonym: "bronchi non-striated muscle" EXACT [OBOL:automatic] synonym: "bronchi smooth muscle" EXACT [OBOL:automatic] synonym: "bronchi smooth muscle tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk involuntary muscle" EXACT [OBOL:automatic] synonym: "bronchial trunk non-striated muscle" EXACT [OBOL:automatic] synonym: "bronchial trunk smooth muscle" EXACT [OBOL:automatic] synonym: "bronchial trunk smooth muscle tissue" EXACT [OBOL:automatic] synonym: "bronchus involuntary muscle" EXACT [OBOL:automatic] synonym: "bronchus non-striated muscle" EXACT [OBOL:automatic] synonym: "bronchus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bronchi" EXACT [OBOL:automatic] synonym: "involuntary muscle of bronchial trunk" EXACT [OBOL:automatic] synonym: "involuntary muscle of bronchus" EXACT [OBOL:automatic] synonym: "non-striated muscle of bronchi" EXACT [OBOL:automatic] synonym: "non-striated muscle of bronchial trunk" EXACT [OBOL:automatic] synonym: "non-striated muscle of bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle of bronchi" EXACT [OBOL:automatic] synonym: "smooth muscle of bronchial trunk" EXACT [OBOL:automatic] synonym: "smooth muscle of bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bronchi" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bronchus" EXACT [OBOL:automatic] xref: MA:0001840 ! bronchus smooth muscle xref: ncithesaurus:Bronchus_Smooth_Muscle_Tissue ! Bronchus Smooth Muscle Tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002185 ! bronchus xref: UMLS:C1707055 [Term] id: UBERON:0004245 name: oviduct smooth muscle def: "A portion of smooth muscle tissue that is part of a fallopian tube [Automatically generated definition]." [OBOL:automatic] synonym: "fallopian tube involuntary muscle" EXACT [OBOL:automatic] synonym: "fallopian tube non-striated muscle" EXACT [OBOL:automatic] synonym: "fallopian tube smooth muscle" EXACT [OBOL:automatic] synonym: "fallopian tube smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "non-striated muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "smooth muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of fallopian tube" EXACT [OBOL:automatic] xref: MA:0001721 ! oviduct smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003889 ! fallopian tube [Term] id: UBERON:0004246 name: outflow tract smooth muscle def: "A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of outflow tract" EXACT [OBOL:automatic] synonym: "non-striated muscle of outflow tract" EXACT [OBOL:automatic] synonym: "outflow tract involuntary muscle" EXACT [OBOL:automatic] synonym: "outflow tract non-striated muscle" EXACT [OBOL:automatic] synonym: "outflow tract smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of outflow tract" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of outflow tract" EXACT [OBOL:automatic] xref: MA:0000492 ! outflow tract smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0004145 ! outflow tract [Term] id: UBERON:0004247 name: back bone def: "A bone that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "back bone organ" EXACT [OBOL:automatic] synonym: "bone of back" EXACT [OBOL:automatic] synonym: "bone organ of back" EXACT [OBOL:automatic] xref: MA:0000494 ! back bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004248 name: pedal digit bone def: "A bone that is part of a hindlimb digit. Typically phalanges but may include sesamoids." [UBERON:cjm] synonym: "foot digit bone" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit bone" EXACT [OBOL:accepted] synonym: "digital bone of foot" EXACT [] synonym: "bone of digit of foot" EXACT [OBOL:automatic] synonym: "bone of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "bone of digitus pedis" EXACT [OBOL:automatic] synonym: "bone of foot digit" EXACT [OBOL:automatic] synonym: "bone of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "bone of toe" EXACT [OBOL:automatic] synonym: "bone organ of digit of foot" EXACT [OBOL:automatic] synonym: "bone organ of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "bone organ of digitus pedis" EXACT [OBOL:automatic] synonym: "bone organ of foot digit" EXACT [OBOL:automatic] synonym: "bone organ of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "bone organ of toe" EXACT [OBOL:automatic] synonym: "digit of foot bone" EXACT [OBOL:automatic] synonym: "digit of foot bone organ" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb bone" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb bone organ" EXACT [OBOL:automatic] synonym: "digitus pedis bone" EXACT [OBOL:automatic] synonym: "digitus pedis bone organ" EXACT [OBOL:automatic] synonym: "foot digit bone organ" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit bone" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit bone organ" EXACT [OBOL:automatic] synonym: "toe bone" EXACT [OBOL:automatic] synonym: "toe bone organ" EXACT [OBOL:automatic] xref: MA:0000646 ! foot digit bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001466 ! pedal digit synonym: "foot digit bone" EXACT [MA:0000646] [Term] id: UBERON:0004249 name: manual digit bone def: "A bone that is part of a forelimb digit. Typically phalanges but may include sesamoids." [UBERON:cjm] synonym: "hand digit bone" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit bone" EXACT [OBOL:accepted] synonym: "digital bone of hand" EXACT [] synonym: "bone of digit of hand" EXACT [OBOL:automatic] synonym: "bone of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone of digitus manus" EXACT [OBOL:automatic] synonym: "bone of finger" EXACT [OBOL:automatic] synonym: "bone of hand digit" EXACT [OBOL:automatic] synonym: "bone of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "bone organ of digit of hand" EXACT [OBOL:automatic] synonym: "bone organ of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone organ of digitus manus" EXACT [OBOL:automatic] synonym: "bone organ of finger" EXACT [OBOL:automatic] synonym: "bone organ of hand digit" EXACT [OBOL:automatic] synonym: "bone organ of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "digit of hand bone" EXACT [OBOL:automatic] synonym: "digit of hand bone organ" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb bone" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb bone organ" EXACT [OBOL:automatic] synonym: "digitus manus bone" EXACT [OBOL:automatic] synonym: "digitus manus bone organ" EXACT [OBOL:automatic] synonym: "finger bone" EXACT [OBOL:automatic] synonym: "finger bone organ" EXACT [OBOL:automatic] synonym: "hand digit bone organ" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit bone" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit bone organ" EXACT [OBOL:automatic] xref: MA:0000622 ! manual digit bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002389 ! manual digit synonym: "hand digit bone" EXACT [MA:0000622] [Term] id: UBERON:0004250 name: upper arm bone def: "A bone that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "Proximal segment of free upper limb bone" EXACT [OBOL:automatic] synonym: "Proximal segment of free upper limb bone organ" EXACT [OBOL:automatic] synonym: "arm stylopod bone" EXACT [OBOL:automatic] synonym: "arm stylopod bone organ" EXACT [OBOL:automatic] synonym: "bone of Proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone of arm stylopod" EXACT [OBOL:automatic] synonym: "bone of brachial region stylopod" EXACT [OBOL:automatic] synonym: "bone of proximal segment of free upper limb stylopod" EXACT [OBOL:automatic] synonym: "bone of stylopod of arm" EXACT [OBOL:automatic] synonym: "bone of stylopod of brachial region" EXACT [OBOL:automatic] synonym: "bone of stylopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone of upper arm" EXACT [OBOL:automatic] synonym: "bone organ of Proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone organ of arm stylopod" EXACT [OBOL:automatic] synonym: "bone organ of brachial region stylopod" EXACT [OBOL:automatic] synonym: "bone organ of proximal segment of free upper limb stylopod" EXACT [OBOL:automatic] synonym: "bone organ of stylopod of arm" EXACT [OBOL:automatic] synonym: "bone organ of stylopod of brachial region" EXACT [OBOL:automatic] synonym: "bone organ of stylopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "bone organ of upper arm" EXACT [OBOL:automatic] synonym: "brachial region stylopod bone" EXACT [OBOL:automatic] synonym: "brachial region stylopod bone organ" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb stylopod bone" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb stylopod bone organ" EXACT [OBOL:automatic] synonym: "stylopod of arm bone" EXACT [OBOL:automatic] synonym: "stylopod of arm bone organ" EXACT [OBOL:automatic] synonym: "stylopod of brachial region bone" EXACT [OBOL:automatic] synonym: "stylopod of brachial region bone organ" EXACT [OBOL:automatic] synonym: "stylopod of proximal segment of free upper limb bone" EXACT [OBOL:automatic] synonym: "stylopod of proximal segment of free upper limb bone organ" EXACT [OBOL:automatic] synonym: "upper arm bone organ" EXACT [OBOL:automatic] xref: MA:0000604 ! upper arm bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0003822 ! upper arm relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton [Term] id: UBERON:0004251 name: hindlimb zeugopod bone def: "A bone that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "bone of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "bone of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "bone of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "bone of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "bone of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "bone of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "bone of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "bone of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "bone of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "bone of lower leg" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "bone of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "bone of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "bone of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "bone of zeugopod of leg" EXACT [OBOL:automatic] synonym: "bone of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "bone organ of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "bone organ of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of lower leg" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of leg" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb middle limb segment bone" EXACT [OBOL:automatic] synonym: "hind limb middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "hind limb zeugopod bone" EXACT [OBOL:automatic] synonym: "hind limb zeugopod bone organ" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment bone" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod bone" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod bone organ" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment bone" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "inferior member zeugopod bone" EXACT [OBOL:automatic] synonym: "inferior member zeugopod bone organ" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb bone" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb bone organ" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment bone" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod bone" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb bone" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb bone" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member bone" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity bone" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb bone" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb bone" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member bone" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of leg bone" EXACT [OBOL:automatic] synonym: "zeugopod of leg bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity bone" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity bone organ" EXACT [OBOL:automatic] synonym: "lower leg bone" EXACT [MA:0000676] xref: MA:0000676 ! lower leg bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0003823 ! lower leg [Term] id: UBERON:0004253 name: skin muscle def: "A muscle organ that is part of a skin of body [Automatically generated definition]." [OBOL:automatic] comment: Editor notes: review as part of general integumentary system review - part of skin, or more generally, integumental system synonym: "muscle organ of skin" EXACT [OBOL:automatic] synonym: "skin muscle organ" EXACT [OBOL:automatic] synonym: "muscle of integumental system" EXACT [EMAPA:18187] xref: MA:0002710 ! skin muscle xref: EMAPA:18187 ! muscle of integumental system intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002416 ! integumental system relationship: located_in UBERON:0002097 ! skin of body [Term] id: UBERON:0001383 name: muscle of leg def: "A muscle that is part of the region of the hindlimb between the pelvis and ankle." [UBERON:cjm, Wikipedia:Leg_muscle] comment: Terminology notes: see notes on UBERON:0000978 for possible confusion over the term 'leg'. subset: uberon_slim synonym: "leg muscle" EXACT [] synonym: "muscle of upper/lower leg" EXACT [] synonym: "leg muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of leg" EXACT [OBOL:automatic] synonym: "muscle of hindlimb zeugopod or stylopod" EXACT [OBOL:automatic, UBERON:cjm] synonym: "muscle of thigh or crus" EXACT [OBOL:automatic, UBERON:cjm] synonym: "muscle of upper or lower hindlimb segment" EXACT [OBOL:automatic, UBERON:cjm] xref: BTO:0000722 ! leg muscle xref: MA:0000672 ! leg muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000978 ! leg [Term] id: UBERON:0004252 name: hindlimb stylopod muscle alt_id: UBERON:0000374 def: "A muscle organ that is part of a hindlimb stylopod (upper leg)[Automatically generated definition]." [OBOL:automatic] synonym: "thigh muscle" EXACT [FMA:22470] synonym: "muscle of thigh" EXACT [FMA:22470] synonym: "upper leg muscle" EXACT [MA:0000684] xref: BTO:0001367 ! thigh muscle xref: FMA:22470 ! Muscle of thigh xref: MA:0000684 ! upper leg muscle xref: SCTID:245013005 ! Entire skeletal muscle of thigh intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004256 name: hindlimb zeugopod muscle def: "A muscle organ that is part of a hindlimb zeugopod (lower leg) [Automatically generated definition]." [OBOL:automatic] comment: Editor notes: the FMA class "muscle of leg" belongs here, do not move. See notes on UBERON:0000978 for possible terminological confusion over term 'leg' synonym: "calf muscle" RELATED [OBOL:automatic] synonym: "lower leg muscle" EXACT [MA:0000678] synonym: "muscle of leg" RELATED INCONSISTENT [FMA:22471] xref: MA:0000678 ! lower leg muscle xref: FMA:22471 ! Muscle of leg xref: SCTID:265806001 ! Entire skeletal muscle of lower leg intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0003823 ! lower leg [Term] id: UBERON:0004463 name: musculature of hindlimb stylopod def: "A musculature that is part of a hindlimb stylopod (upper leg / thigh)[Automatically generated definition]." [OBOL:automatic] synonym: "musculature of thigh" EXACT [FMA:50208] synonym: "muscle group of thigh" EXACT [FMA:50208] synonym: "set of muscles of thigh" EXACT [FMA:50208] synonym: "thigh musculature" EXACT [FMA:50208] xref: FMA:50208 ! Musculature of thigh intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000376 ! part_of upper leg [Term] id: UBERON:0006067 name: musculature of hindlimb zeugopod synonym: "leg musculature" EXACT [FMA:50211] synonym: "muscle group of leg" EXACT [FMA:50211] synonym: "set of muscles of leg" EXACT [FMA:50211] xref: FMA:50211 ! musculature of leg intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod def: "A musculature that is part of a hindlimb zeugopod." [OBOL:automatic] [Term] id: UBERON:0004466 name: musculature of leg alt_id: UBERON:0005632 def: "A musculature that is part of a lower leg or upper leg [Automatically generated definition]." [OBOL:automatic] comment: see notes on UBERON:0000978 for possible confusion over the term 'leg'. This class represents the class-union of upper leg musculature and lower leg musculature (and thus may not mean precisely the same thing as the EHDAA2 class) synonym: "leg muscle system" EXACT [EHDAA2:0000973] xref: EHDAA2:0000973 ! leg muscle system intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000978 ! part_of leg [Term] id: UBERON:0013511 name: ambiens muscle def: "The tendon of the ambiens muscle passes obliquely over the knee joint. It assists in the control of the bird’s toes. This muscle is present in some reptiles but not mammals. It is present in caiques and some other South American genera, but missing in most parrot genera. This was first noted by Garrod (1874) who proposed using this and other anatomical differences to classify parrots. For other anatomical differences among parrots see carotid arteries, furcula, and uropygial gland. " [http://caiquesite.com/glossary.htm] synonym: "ambiens" RELATED [] is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0002103 ! hindlimb relationship: only_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: UBERON:0004257 name: upper leg blood vessel def: "A blood vessel that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of stylopod of hind limb" EXACT [OBOL:automatic] synonym: "blood vessel of stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "blood vessel of thigh" EXACT [OBOL:automatic] synonym: "blood vessel of upper leg" EXACT [OBOL:automatic] synonym: "hind limb stylopod blood vessel" EXACT [OBOL:automatic] synonym: "hindlimb stylopod blood vessel" EXACT [OBOL:automatic] synonym: "thigh blood vessel" EXACT [OBOL:automatic] xref: MA:0000681 ! upper leg blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004258 name: back blood vessel def: "A blood vessel that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of back" EXACT [OBOL:automatic] xref: MA:0000493 ! back blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004259 name: lower arm blood vessel def: "A blood vessel that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "forelimb zeugopod blood vessel" EXACT [UBERON:cjm] xref: MA:0000597 ! lower arm blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002386 ! lower segment of arm [Term] id: UBERON:0004260 name: upper arm blood vessel def: "A blood vessel that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "forelimb stylopod blood vessel" EXACT [UBERON:cjm] xref: MA:0000603 ! upper arm blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003822 ! upper arm [Term] id: UBERON:0004261 name: lower leg blood vessel def: "A blood vessel that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "hindlimb zeugopod blood vessel" EXACT [UBERON:cjm] xref: MA:0000675 ! lower leg blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003823 ! lower leg [Term] id: UBERON:0004262 name: upper leg skin def: "A zone of skin that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "Proximal segment of free lower limb skin" EXACT [OBOL:automatic] synonym: "hind limb stylopod skin" EXACT [OBOL:automatic] synonym: "hindlimb stylopod skin" EXACT [OBOL:automatic] synonym: "inferior member stylopod skin" EXACT [OBOL:automatic] synonym: "lower extremity stylopod skin" EXACT [OBOL:automatic] synonym: "skin of Proximal segment of free lower limb" EXACT [OBOL:automatic] synonym: "skin of hind limb stylopod" EXACT [OBOL:automatic] synonym: "skin of hindlimb stylopod" EXACT [OBOL:automatic] synonym: "skin of inferior member stylopod" EXACT [OBOL:automatic] synonym: "skin of lower extremity stylopod" EXACT [OBOL:automatic] synonym: "skin of stylopod of hind limb" EXACT [OBOL:automatic] synonym: "skin of stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "skin of stylopod of inferior member" EXACT [OBOL:automatic] synonym: "skin of stylopod of lower extremity" EXACT [OBOL:automatic] synonym: "skin of stylopod of lower limb" EXACT [OBOL:automatic] synonym: "skin of thigh" EXACT [OBOL:automatic] synonym: "skin of upper leg" EXACT [OBOL:automatic] synonym: "stylopod of hind limb skin" EXACT [OBOL:automatic] synonym: "stylopod of hindlimb skin" EXACT [OBOL:automatic] synonym: "stylopod of inferior member skin" EXACT [OBOL:automatic] synonym: "stylopod of lower extremity skin" EXACT [OBOL:automatic] synonym: "stylopod of lower limb skin" EXACT [OBOL:automatic] synonym: "thigh skin" EXACT [OBOL:automatic] xref: MA:0000686 ! upper leg skin xref: FMA:37790 ! Skin of thigh xref: EMAPA:18159 ! skin of upper leg (also: UBERON:0001511 'skin of leg') intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000376 ! hindlimb stylopod xref: SCTID:181547006 ! Entire skin of thigh [Term] id: UBERON:0004263 name: upper arm skin def: "A zone of skin that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "Proximal segment of free upper limb skin" EXACT [OBOL:automatic] synonym: "arm stylopod skin" EXACT [OBOL:automatic] synonym: "brachial region stylopod skin" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb stylopod skin" EXACT [OBOL:automatic] synonym: "skin of Proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "skin of arm stylopod" EXACT [OBOL:automatic] synonym: "skin of brachial region stylopod" EXACT [OBOL:automatic] synonym: "skin of proximal segment of free upper limb stylopod" EXACT [OBOL:automatic] synonym: "skin of stylopod of arm" EXACT [OBOL:automatic] synonym: "skin of stylopod of brachial region" EXACT [OBOL:automatic] synonym: "skin of stylopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "skin of upper arm" EXACT [OBOL:automatic] synonym: "stylopod of arm skin" EXACT [OBOL:automatic] synonym: "stylopod of brachial region skin" EXACT [OBOL:automatic] synonym: "stylopod of proximal segment of free upper limb skin" EXACT [OBOL:automatic] xref: MA:0000608 ! upper arm skin xref: EMAPA:18062 ! skin of upper arm (also: UBERON:0002427 'arm skin') intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0003822 ! upper arm xref: SCTID:181531009 ! Entire skin of upper arm [Term] id: UBERON:0004264 name: lower leg skin def: "A zone of skin that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb middle limb segment skin" EXACT [OBOL:automatic] synonym: "hind limb zeugopod skin" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment skin" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod skin" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment skin" EXACT [OBOL:automatic] synonym: "inferior member zeugopod skin" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb skin" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment skin" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod skin" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb skin" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb skin" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member skin" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity skin" EXACT [OBOL:automatic] synonym: "skin of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "skin of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "skin of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "skin of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "skin of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "skin of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "skin of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "skin of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "skin of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "skin of lower leg" EXACT [OBOL:automatic] synonym: "skin of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "skin of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "skin of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "skin of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "skin of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "skin of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "skin of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "skin of zeugopod of leg" EXACT [OBOL:automatic] synonym: "skin of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb skin" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb skin" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member skin" EXACT [OBOL:automatic] synonym: "zeugopod of leg skin" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity skin" EXACT [OBOL:automatic] xref: MA:0000680 ! lower leg skin xref: EMAPA:18156 ! skin of lower leg (also: UBERON:0001511 'skin of leg') intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0003823 ! lower leg xref: SCTID:244180007 ! Entire skin of lower leg [Term] id: UBERON:0004265 name: outflow tract myocardium def: "A myocardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle of outflow tract" EXACT [OBOL:automatic] synonym: "heart muscle of outflow tract" EXACT [OBOL:automatic] synonym: "heart myocardium of outflow tract" EXACT [OBOL:automatic] synonym: "muscle of heart of outflow tract" EXACT [OBOL:automatic] synonym: "myocardium of outflow tract" EXACT [OBOL:automatic] synonym: "outflow tract cardiac muscle" EXACT [OBOL:automatic] synonym: "outflow tract heart muscle" EXACT [OBOL:automatic] synonym: "outflow tract heart myocardium" EXACT [OBOL:automatic] synonym: "outflow tract muscle of heart" EXACT [OBOL:automatic] xref: MA:0000489 ! outflow tract myocardium xref: VHOG:0000603 ! outflow tract myocardium xref: EHDAA2:0001358 ! outflow tract myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0004145 ! outflow tract property_value: homology_notes " (...) (theme) is how the vertebrate cardiovascular system differs from that of the presumptive evolutionary chordate ancestor. (...) At best we can tell there are two essential new ingredients: (1) vertebrates all have a continuous endothelial lining to the heart and vessels and (2) vertebrates have developed a second chamber in the heart, one designed for generating high systemic blood pressure.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000603", ontology="VHOG", source="PMID:9187138 Fishman MC\, Chien KR\, Fashioning the vertebrate heart: earliest embryonic decisions. Development (1997)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004266 name: upper leg connective tissue def: "A portion of connective tissue that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "Proximal segment of free lower limb connective tissue" EXACT [OBOL:automatic] synonym: "Proximal segment of free lower limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "Proximal segment of free lower limb textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of Proximal segment of free lower limb" EXACT [OBOL:automatic] synonym: "connective tissue of hind limb stylopod" EXACT [OBOL:automatic] synonym: "connective tissue of hindlimb stylopod" EXACT [OBOL:automatic] synonym: "connective tissue of inferior member stylopod" EXACT [OBOL:automatic] synonym: "connective tissue of lower extremity stylopod" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of hind limb" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of inferior member" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of lower extremity" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of lower limb" EXACT [OBOL:automatic] synonym: "connective tissue of thigh" EXACT [OBOL:automatic] synonym: "connective tissue of upper leg" EXACT [OBOL:automatic] synonym: "hind limb stylopod connective tissue" EXACT [OBOL:automatic] synonym: "hind limb stylopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "hind limb stylopod textus connectivus" EXACT [OBOL:automatic] synonym: "hindlimb stylopod connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb stylopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb stylopod textus connectivus" EXACT [OBOL:automatic] synonym: "inferior member stylopod connective tissue" EXACT [OBOL:automatic] synonym: "inferior member stylopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "inferior member stylopod textus connectivus" EXACT [OBOL:automatic] synonym: "lower extremity stylopod connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity stylopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity stylopod textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of Proximal segment of free lower limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hind limb stylopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hindlimb stylopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of inferior member stylopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower extremity stylopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of hind limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of inferior member" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of lower extremity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of lower limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of thigh" EXACT [OBOL:automatic] synonym: "portion of connective tissue of upper leg" EXACT [OBOL:automatic] synonym: "stylopod of hind limb connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of hind limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of hind limb textus connectivus" EXACT [OBOL:automatic] synonym: "stylopod of hindlimb connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of hindlimb portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of hindlimb textus connectivus" EXACT [OBOL:automatic] synonym: "stylopod of inferior member connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of inferior member portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of inferior member textus connectivus" EXACT [OBOL:automatic] synonym: "stylopod of lower extremity connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of lower extremity portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of lower extremity textus connectivus" EXACT [OBOL:automatic] synonym: "stylopod of lower limb connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of lower limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of lower limb textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of Proximal segment of free lower limb" EXACT [OBOL:automatic] synonym: "textus connectivus of hind limb stylopod" EXACT [OBOL:automatic] synonym: "textus connectivus of hindlimb stylopod" EXACT [OBOL:automatic] synonym: "textus connectivus of inferior member stylopod" EXACT [OBOL:automatic] synonym: "textus connectivus of lower extremity stylopod" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of hind limb" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of inferior member" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of lower extremity" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of lower limb" EXACT [OBOL:automatic] synonym: "textus connectivus of thigh" EXACT [OBOL:automatic] synonym: "textus connectivus of upper leg" EXACT [OBOL:automatic] synonym: "thigh connective tissue" EXACT [OBOL:automatic] synonym: "thigh portion of connective tissue" EXACT [OBOL:automatic] synonym: "thigh textus connectivus" EXACT [OBOL:automatic] synonym: "upper leg portion of connective tissue" EXACT [OBOL:automatic] synonym: "upper leg textus connectivus" EXACT [OBOL:automatic] xref: MA:0000683 ! upper leg connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004267 name: back connective tissue def: "A portion of connective tissue that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "back portion of connective tissue" EXACT [OBOL:automatic] synonym: "back textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of back" EXACT [OBOL:automatic] synonym: "portion of connective tissue of back" EXACT [OBOL:automatic] synonym: "textus connectivus of back" EXACT [OBOL:automatic] xref: MA:0000495 ! back connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004268 name: lower arm connective tissue def: "A portion of connective tissue that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "antebrachial region connective tissue" EXACT [OBOL:automatic] synonym: "antebrachial region portion of connective tissue" EXACT [OBOL:automatic] synonym: "antebrachial region textus connectivus" EXACT [OBOL:automatic] synonym: "arm middle limb segment connective tissue" EXACT [OBOL:automatic] synonym: "arm middle limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "arm middle limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "arm zeugopod connective tissue" EXACT [OBOL:automatic] synonym: "arm zeugopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "arm zeugopod textus connectivus" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment connective tissue" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "brachial region zeugopod connective tissue" EXACT [OBOL:automatic] synonym: "brachial region zeugopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "brachial region zeugopod textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of antebrachial region" EXACT [OBOL:automatic] synonym: "connective tissue of arm middle limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of arm zeugopod" EXACT [OBOL:automatic] synonym: "connective tissue of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "connective tissue of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "connective tissue of lower arm" EXACT [OBOL:automatic] synonym: "connective tissue of lower segment of arm" EXACT [OBOL:automatic] synonym: "connective tissue of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "connective tissue of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "connective tissue of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "connective tissue of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of arm" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "intermediate segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "lower arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower arm textus connectivus" EXACT [OBOL:automatic] synonym: "lower segment of arm connective tissue" EXACT [OBOL:automatic] synonym: "lower segment of arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower segment of arm textus connectivus" EXACT [OBOL:automatic] synonym: "middle limb segment of arm connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of arm textus connectivus" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region portion of connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region textus connectivus" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of proximal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of antebrachial region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of arm middle limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of arm zeugopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower segment of arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb middle limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb zeugopod textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of antebrachial region" EXACT [OBOL:automatic] synonym: "textus connectivus of arm middle limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of arm zeugopod" EXACT [OBOL:automatic] synonym: "textus connectivus of brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of brachial region zeugopod" EXACT [OBOL:automatic] synonym: "textus connectivus of intermediate segment of free upper limb" EXACT [OBOL:automatic] synonym: "textus connectivus of lower arm" EXACT [OBOL:automatic] synonym: "textus connectivus of lower segment of arm" EXACT [OBOL:automatic] synonym: "textus connectivus of middle limb segment of arm" EXACT [OBOL:automatic] synonym: "textus connectivus of middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "textus connectivus of middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "textus connectivus of proximal segment of free upper limb middle limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of proximal segment of free upper limb zeugopod" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of arm" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "zeugopod of arm connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of arm textus connectivus" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of brachial region textus connectivus" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of proximal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] xref: MA:0000599 ! lower arm connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002386 ! lower segment of arm [Term] id: UBERON:0004269 name: upper arm connective tissue def: "A portion of connective tissue that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "Proximal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "Proximal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "Proximal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "arm stylopod connective tissue" EXACT [OBOL:automatic] synonym: "arm stylopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "arm stylopod textus connectivus" EXACT [OBOL:automatic] synonym: "brachial region stylopod connective tissue" EXACT [OBOL:automatic] synonym: "brachial region stylopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "brachial region stylopod textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of Proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "connective tissue of arm stylopod" EXACT [OBOL:automatic] synonym: "connective tissue of brachial region stylopod" EXACT [OBOL:automatic] synonym: "connective tissue of proximal segment of free upper limb stylopod" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of arm" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of brachial region" EXACT [OBOL:automatic] synonym: "connective tissue of stylopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "connective tissue of upper arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of Proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of arm stylopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of brachial region stylopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of proximal segment of free upper limb stylopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of arm" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of brachial region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of stylopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of upper arm" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb stylopod connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb stylopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb stylopod textus connectivus" EXACT [OBOL:automatic] synonym: "stylopod of arm connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of arm textus connectivus" EXACT [OBOL:automatic] synonym: "stylopod of brachial region connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of brachial region portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of brachial region textus connectivus" EXACT [OBOL:automatic] synonym: "stylopod of proximal segment of free upper limb connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of proximal segment of free upper limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "stylopod of proximal segment of free upper limb textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of Proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "textus connectivus of arm stylopod" EXACT [OBOL:automatic] synonym: "textus connectivus of brachial region stylopod" EXACT [OBOL:automatic] synonym: "textus connectivus of proximal segment of free upper limb stylopod" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of arm" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of brachial region" EXACT [OBOL:automatic] synonym: "textus connectivus of stylopod of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "textus connectivus of upper arm" EXACT [OBOL:automatic] synonym: "upper arm portion of connective tissue" EXACT [OBOL:automatic] synonym: "upper arm textus connectivus" EXACT [OBOL:automatic] xref: MA:0000605 ! upper arm connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0003822 ! upper arm [Term] id: UBERON:0004270 name: lower leg connective tissue def: "A portion of connective tissue that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "connective tissue of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "connective tissue of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "connective tissue of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "connective tissue of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "connective tissue of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "connective tissue of lower leg" EXACT [OBOL:automatic] synonym: "connective tissue of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "connective tissue of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "connective tissue of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "connective tissue of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of leg" EXACT [OBOL:automatic] synonym: "connective tissue of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb middle limb segment connective tissue" EXACT [OBOL:automatic] synonym: "hind limb middle limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "hind limb middle limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "hind limb zeugopod connective tissue" EXACT [OBOL:automatic] synonym: "hind limb zeugopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "hind limb zeugopod textus connectivus" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod textus connectivus" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment connective tissue" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "inferior member zeugopod connective tissue" EXACT [OBOL:automatic] synonym: "inferior member zeugopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "inferior member zeugopod textus connectivus" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb connective tissue" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb textus connectivus" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment textus connectivus" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod textus connectivus" EXACT [OBOL:automatic] synonym: "lower leg portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower leg textus connectivus" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb textus connectivus" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb portion of connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb textus connectivus" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member portion of connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member textus connectivus" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity portion of connective tissue" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower leg" EXACT [OBOL:automatic] synonym: "portion of connective tissue of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "portion of connective tissue of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of leg" EXACT [OBOL:automatic] synonym: "portion of connective tissue of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "textus connectivus of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "textus connectivus of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "textus connectivus of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "textus connectivus of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "textus connectivus of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "textus connectivus of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "textus connectivus of lower leg" EXACT [OBOL:automatic] synonym: "textus connectivus of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "textus connectivus of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "textus connectivus of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "textus connectivus of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of leg" EXACT [OBOL:automatic] synonym: "textus connectivus of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb textus connectivus" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb textus connectivus" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member textus connectivus" EXACT [OBOL:automatic] synonym: "zeugopod of leg connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of leg portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of leg textus connectivus" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity portion of connective tissue" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity textus connectivus" EXACT [OBOL:automatic] xref: MA:0000677 ! lower leg connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0003823 ! lower leg [Term] id: UBERON:0004271 name: outflow tract pericardium def: "A pericardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "pericardium of outflow tract" EXACT [OBOL:automatic] xref: MA:0000491 ! outflow tract pericardium intersection_of: UBERON:0002407 ! pericardium intersection_of: part_of UBERON:0004145 ! outflow tract [Term] id: UBERON:0004273 name: cartilaginous joint suture def: "A cranial suture that is part of a cartilaginous joint [Automatically generated definition]." [OBOL:automatic] synonym: "articulatio cartilaginea cranial suture" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea cranial sutures" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea cranial sutures set" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea cranium suture" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea suture of cranium" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranial suture" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranial sutures" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranial sutures set" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranium suture" EXACT [OBOL:automatic] synonym: "cartilaginous joint suture of cranium" EXACT [OBOL:automatic] synonym: "cranial suture of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranial suture of cartilaginous joint" EXACT [OBOL:automatic] synonym: "cranial sutures of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranial sutures of cartilaginous joint" EXACT [OBOL:automatic] synonym: "cranial sutures set of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranial sutures set of cartilaginous joint" EXACT [OBOL:automatic] synonym: "cranium suture of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranium suture of cartilaginous joint" EXACT [OBOL:automatic] synonym: "suture of cranium of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "suture of cranium of cartilaginous joint" EXACT [OBOL:automatic] xref: MA:0001498 ! cartilaginous joint suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: part_of UBERON:0002213 ! cartilaginous joint [Term] id: UBERON:0004274 name: lateral ventricle choroid plexus epithelium def: "A choroid plexus epithelium that is part of a lateral ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "chorioid plexus of cerebral hemisphere epithelial tissue of lateral ventricle" EXACT [OBOL:automatic] synonym: "chorioid plexus of cerebral hemisphere epithelium of lateral ventricle" EXACT [OBOL:automatic] synonym: "choroid plexus epithelial tissue of lateral ventricle" EXACT [OBOL:automatic] synonym: "choroid plexus epithelium of lateral ventricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of chorioid plexus of cerebral hemisphere of lateral ventricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of choroid plexus of lateral ventricle" EXACT [OBOL:automatic] synonym: "epithelium of chorioid plexus of cerebral hemisphere of lateral ventricle" EXACT [OBOL:automatic] synonym: "epithelium of choroid plexus of lateral ventricle" EXACT [OBOL:automatic] synonym: "lateral ventricle chorioid plexus of cerebral hemisphere epithelial tissue" EXACT [OBOL:automatic] synonym: "lateral ventricle chorioid plexus of cerebral hemisphere epithelium" EXACT [OBOL:automatic] synonym: "lateral ventricle choroid plexus epithelial tissue" EXACT [OBOL:automatic] synonym: "lateral ventricle epithelial tissue of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "lateral ventricle epithelial tissue of choroid plexus" EXACT [OBOL:automatic] synonym: "lateral ventricle epithelium of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "lateral ventricle epithelium of choroid plexus" EXACT [OBOL:automatic] xref: MA:0000962 ! lateral ventricle choroid plexus epithelium xref: FMA:242815 ! Epithelium of choroid plexus of lateral ventricle intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002307 ! choroid plexus of lateral ventricle xref: ncithesaurus:Choroid_Plexus_Epithelium_of_the_Lateral_Ventricle ! Choroid Plexus Epithelium of the Lateral Ventricle xref: EHDAA2:0004450 ! lateral ventricle choroid plexus epithelium xref: UMLS:C1711323 [Term] id: UBERON:0004275 name: third ventricle choroid plexus epithelium def: "A choroid plexus epithelium that is part of a third ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "chorioid plexus of cerebral hemisphere epithelial tissue of third ventricle" EXACT [OBOL:automatic] synonym: "chorioid plexus of cerebral hemisphere epithelium of third ventricle" EXACT [OBOL:automatic] synonym: "choroid plexus epithelial tissue of third ventricle" EXACT [OBOL:automatic] synonym: "choroid plexus epithelium of third ventricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of chorioid plexus of cerebral hemisphere of third ventricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of choroid plexus of third ventricle" EXACT [OBOL:automatic] synonym: "epithelium of chorioid plexus of cerebral hemisphere of third ventricle" EXACT [OBOL:automatic] synonym: "epithelium of choroid plexus of third ventricle" EXACT [OBOL:automatic] synonym: "third ventricle chorioid plexus of cerebral hemisphere epithelial tissue" EXACT [OBOL:automatic] synonym: "third ventricle chorioid plexus of cerebral hemisphere epithelium" EXACT [OBOL:automatic] synonym: "third ventricle choroid plexus epithelial tissue" EXACT [OBOL:automatic] synonym: "third ventricle epithelial tissue of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "third ventricle epithelial tissue of choroid plexus" EXACT [OBOL:automatic] synonym: "third ventricle epithelium of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "third ventricle epithelium of choroid plexus" EXACT [OBOL:automatic] xref: MA:0000880 ! third ventricle choroid plexus epithelium xref: FMA:242821 ! Epithelium of choroid plexus of third ventricle intersection_of: UBERON:0003911 ! choroid plexus epithelium intersection_of: part_of UBERON:0002286 ! third ventricle relationship: part_of UBERON:0002288 ! choroid plexus of third ventricle [Term] id: UBERON:0004276 name: fourth ventricle choroid plexus epithelium def: "A choroid plexus epithelium that is part of a fourth ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "chorioid plexus of cerebral hemisphere epithelial tissue of fourth ventricle" EXACT [OBOL:automatic] synonym: "chorioid plexus of cerebral hemisphere epithelium of fourth ventricle" EXACT [OBOL:automatic] synonym: "choroid plexus epithelial tissue of fourth ventricle" EXACT [OBOL:automatic] synonym: "choroid plexus epithelium of fourth ventricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of chorioid plexus of cerebral hemisphere of fourth ventricle" EXACT [OBOL:automatic] synonym: "epithelial tissue of choroid plexus of fourth ventricle" EXACT [OBOL:automatic] synonym: "epithelium of chorioid plexus of cerebral hemisphere of fourth ventricle" EXACT [OBOL:automatic] synonym: "epithelium of choroid plexus of fourth ventricle" EXACT [OBOL:automatic] synonym: "fourth ventricle chorioid plexus of cerebral hemisphere epithelial tissue" EXACT [OBOL:automatic] synonym: "fourth ventricle chorioid plexus of cerebral hemisphere epithelium" EXACT [OBOL:automatic] synonym: "fourth ventricle choroid plexus epithelial tissue" EXACT [OBOL:automatic] synonym: "fourth ventricle epithelial tissue of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "fourth ventricle epithelial tissue of choroid plexus" EXACT [OBOL:automatic] synonym: "fourth ventricle epithelium of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "fourth ventricle epithelium of choroid plexus" EXACT [OBOL:automatic] xref: MA:0000984 ! fourth ventricle choroid plexus epithelium xref: FMA:242823 ! Epithelium of choroid plexus of fourth ventricle intersection_of: UBERON:0003911 ! choroid plexus epithelium intersection_of: part_of UBERON:0002422 ! fourth ventricle relationship: part_of UBERON:0002290 ! choroid plexus of fourth ventricle xref: ncithesaurus:Choroid_Plexus_Epithelium_of_the_Fourth_Ventricle ! Choroid Plexus Epithelium of the Fourth Ventricle xref: UMLS:C1707392 [Term] id: UBERON:0010075 name: sacral neural crest def: "One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. The vagal and sacral neural crest cells develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia." [XB:curator, http://www.ncbi.nlm.nih.gov/books/NBK10065/] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0002342 ! neural crest xref: XAO:0004192 ! sacral neural crest [Term] id: UBERON:0004293 name: parasympathetic nerve namespace: uberon def: "A nerve that is part of a parasympathetic nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of parasympathetic nervous system" EXACT [OBOL:automatic] xref: MA:0000224 ! parasympathetic nerve xref: VHOG:0000641 ! parasympathetic nerve xref: EHDAA2:0001401 ! parasympathetic nerve xref: EMAPA:17271 ! nerve of parasympathetic intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000011 ! part_of parasympathetic nervous system relationship: has_developmental_contribution_from UBERON:0005428 {source="NBK10065"} ! vagal neural crest relationship: has_developmental_contribution_from UBERON:0010075 {source="NBK10065"} ! sacral neural crest xref: SCTID:276146002 ! Entire parasympathetic nerve [Term] id: UBERON:0004294 name: glomerular capillary endothelium namespace: uberon synonym: "renal glomerulus capillary endothelium" EXACT [OBOL:automatic] xref: MA:0001658 ! glomerular capillary endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004212 ! glomerular capillary xref: ncithesaurus:Endothelium_of_the_Glomerular_Capillary ! Endothelium of the Glomerular Capillary xref: SCTID:243993006 ! Entire glomerular capillary endothelium def: "An endothelium that is part of a glomerular capillary." [OBOL:automatic] xref: UMLS:C0227647 [Term] id: UBERON:0004295 name: sympathetic nerve trunk namespace: uberon def: "A nerve trunk that is part of a sympathetic nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "nerve trunk of sympathetic nervous system" EXACT [OBOL:automatic] synonym: "nerve trunk of sympathetic part of autonomic division of nervous system" EXACT [OBOL:automatic] synonym: "sympathetic nervous system nerve trunk" EXACT [OBOL:automatic] xref: MA:0000227 ! sympathetic nerve trunk xref: EHDAA2:0001970 ! sympathetic nerve trunk xref: EMAPA:16986 ! nerve trunk (also: UBERON:0001147 'trunk of peripheral nerve') (also: UBERON:0002464 'nerve trunk') (also: UBERON:0003439 'nerve of trunk region') intersection_of: UBERON:0002464 ! nerve trunk intersection_of: part_of UBERON:0000013 ! part_of sympathetic nervous system [Term] id: UBERON:0004296 name: respiratory system lymphatic vessel smooth muscle namespace: uberon def: "A lymphatic vessel smooth muscle that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "smooth muscle of lymph vessel of respiratory system" EXACT [OBOL:automatic] xref: MA:0001826 ! respiratory system lymphatic vessel smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003456 ! respiratory system lymphatic vessel relationship: part_of UBERON:0003456 ! respiratory system lymphatic vessel [Term] id: UBERON:0004297 name: respiratory system blood vessel smooth muscle namespace: uberon def: "A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "smooth muscle tissue of blood vessel of respiratory system" EXACT [OBOL:automatic] xref: MA:0001806 ! respiratory system blood vessel smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003504 ! respiratory system blood vessel [Term] id: UBERON:0004300 name: distal phalanx def: "Terminal phalanx located at the tip of the digits." [Wikipedia:Distal_phalanges] comment: Taxon notes: In human anatomy, the distal phalanges of the four fingers and toes articulate proximally with the intermediate phalanges at the distal interphalangeal joints (DIP); in the thumb and big toe, with only two phalanges, the distal phalanges articulate proximally with the proximal phalanges. The distal phalanges carry and shape nails and claws and are therefore occasionally referred to as the ungual phalanges. The distal phalanges are cone-shaped in most mammals, including most primates, but relatively wide and flat in humans. AO notes: synonym: "ungual phalanx" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] synonym: "terminal phalanx" EXACT [AAO:0010676] synonym: "phalanx distalis" EXACT [Wikipedia:Distal_phalanges] xref: MA:0002914 ! distal phalanx xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Scheme_human_hand_bones-en.svg/200px-Scheme_human_hand_bones-en.svg.png intersection_of: UBERON:0003221 ! phalanx intersection_of: proximally_connected_to UBERON:0004301 ! middle phalanx relationship: part_of UBERON:0009551 ! distal segment of digit xref: AAO:0010676 ! terminal phalanx xref: SCTID:299711006 ! Entire distal phalanx synonym: "Phalanx distalis" RELATED LATIN [Wikipedia:Distal_phalanges] xref: http://upload.wikimedia.org/wikipedia/commons/a/ab/Scheme_human_hand_bones-en.svg [Term] id: UBERON:0004301 name: middle phalanx def: "A phalanx located between proximal and distal phalanges[CJM]. Intermediate phalanges are bones found in the limbs of most vertebrates. In humans, they are the bones of the finger and toe which lie in the middle, between the two wrinkly joints. The thumb and big toe do not have intermediate phalanges. In most other vertebrates, they have a corresponding place in their limbs, whether they be paw, wing, hoof or fin[WP]." [Wikipedia:Intermediate_phalanges] comment: Taxon notes: in some groups such as whales, there are multiple intermediate phalanges. Editors note: consider using numbering system, and axioms to the effect that there is a single middle phalanx per finger in humans. This should perhaps be renamed 'intermediate phalanx', leaving the term middle phalanx open for the specific intermediate phalanx of a 3-phalanx digit synonym: "medial phalanx" RELATED [] synonym: "intermediate phalanx" EXACT [] synonym: "penultimate phalanx" RELATED [AAO:0010677] xref: MA:0002915 ! middle phalanx intersection_of: UBERON:0003221 ! phalanx intersection_of: distally_connected_to UBERON:0003221 ! phalanx intersection_of: proximally_connected_to UBERON:0003221 ! phalanx relationship: distally_connected_to UBERON:0004300 {gci_relation="part_of", gci_filler="NCBITaxon:314146", notes="human and mouse"} ! distal phalanx relationship: proximally_connected_to UBERON:0004302 {gci_relation="part_of", gci_filler="NCBITaxon:314146", notes="human and mouse"} ! proximal phalanx relationship: transitively_distally_connected_to UBERON:0004300 ! distal phalanx relationship: transitively_proximally_connected_to UBERON:0004302 ! proximal phalanx xref: SCTID:299710007 ! Entire middle phalanx xref: AAO:0010677 ! penultimate phalanx [Term] id: UBERON:0004302 name: proximal phalanx def: "Proximal-most phalanx within a digit[CJM]. Proximal phalanges are bones found in the limbs of most vertebrates. In humans, they are the bones at the base of a toe or finger, the prominent, knobby ends of which are often called the knuckles. In other vertebrates, proximal phalanges have a similar placement in the corresponding limbs, be they paw, wing or fin. In many species, they are the longest and thickest phalanx ('finger' bone)[WP]." [Wikipedia:Proximal_phalanges] synonym: "proximal-most phalanx" EXACT [AAO:0010680] synonym: "phalanx 1" EXACT [] synonym: "phalanx I" EXACT [] xref: MA:0002916 ! proximal phalanx xref: AAO:0010680 ! proximal-most phalanx intersection_of: UBERON:0003221 ! phalanx intersection_of: connected_to UBERON:0003821 ! metapodium bone xref: SCTID:299708005 ! Entire proximal phalanx property_value: phalanx_number "1" xsd:nonNegativeInteger [Term] id: UBERON:0004337 name: distal phalanx of manual digit 1 def: "A distal phalanx that is part of a hand digit 1 [Automatically generated definition]." [OBOL:automatic] comment: Taxon notes: The human pollical distal phalanx (PDP) has a pronounced insertion for the flexor pollicis longus (asymmetric towards the radial side), an ungual fossa, and a pair of dissymmetric ungual spines (the ulnar being more prominent). This asymmetry is necessary to ensure that the thumb pulp is always facing the pulps of the other digits, an osteological configuration which provides the maximum contact surface with held objects.[WP] synonym: "distal phalanx of thumb" EXACT [OBOL:automatic] synonym: "thumb distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of first digit of hand" EXACT [FMA:23945] synonym: "first distal phalanx of hand" EXACT [FMA:23945] synonym: "pollical distal phalanx" EXACT [Wikipedia:Distal_phalanges#Thumb] synonym: "PDP" EXACT [Wikipedia:Distal_phalanges#Thumb] xref: FMA:23945 ! distal phalanx of thumb intersection_of: UBERON:0004300 intersection_of: part_of UBERON:0001463 ! manual digit 1 xref: SCTID:182007006 ! Entire distal phalanx of thumb relationship: proximally_connected_to UBERON:0004338 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! proximal phalanx of manual digit 1 [Term] id: UBERON:0004311 name: distal phalanx of manual digit 2 def: "A distal phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "2nd digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "2nd finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "distal phalanx of second finger" EXACT [OBOL:automatic] synonym: "hand digit 2 distal phalanx" EXACT [OBOL:automatic] synonym: "second finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of index finger" EXACT [FMA:23946] synonym: "distal phalanx of second digit of hand" EXACT [FMA:23946] synonym: "second distal phalanx of hand" EXACT [FMA:23946] xref: FMA:23946 ! distal phalanx of index finger intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003622 ! part_of manual digit 2 xref: SCTID:361784003 ! Entire distal phalanx of index finger relationship: proximally_connected_to UBERON:0004320 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 2 [Term] id: UBERON:0004312 name: distal phalanx of manual digit 3 def: "A distal phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "3rd digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "3rd finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "distal phalanx of third finger" EXACT [OBOL:automatic] synonym: "hand digit 3 distal phalanx" EXACT [OBOL:automatic] synonym: "third finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of middle finger" EXACT [FMA:23947] synonym: "distal phalanx of third digit of hand" EXACT [FMA:23947] synonym: "third distal phalanx of hand" EXACT [FMA:23947] xref: FMA:23947 ! distal phalanx of middle finger intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003623 ! part_of manual digit 3 xref: SCTID:361786001 ! Entire distal phalanx of middle finger relationship: proximally_connected_to UBERON:0004321 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 3 [Term] id: UBERON:0004313 name: distal phalanx of manual digit 4 def: "A distal phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "4th digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "4th finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "distal phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "fourth finger distal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 4 distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of ring finger" EXACT [FMA:23948] synonym: "distal phalanx of fourth digit of hand" EXACT [FMA:23948] synonym: "fourth distal phalanx of hand" EXACT [FMA:23948] xref: FMA:23948 ! distal phalanx of ring finger intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003624 ! part_of manual digit 4 xref: SCTID:361788000 ! Entire distal phalanx of ring finger relationship: proximally_connected_to UBERON:0004322 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 4 [Term] id: UBERON:0004314 name: distal phalanx of manual digit 5 def: "A distal phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "5th digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "5th finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "distal phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "fifth finger distal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 5 distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of little finger" EXACT [FMA:23949] synonym: "distal phalanx of fifth digit of hand" EXACT [FMA:23949] synonym: "fifth distal phalanx of hand" EXACT [FMA:23949] xref: FMA:23949 ! distal phalanx of little finger intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003625 ! part_of manual digit 5 xref: SCTID:361790004 ! Entire distal phalanx of little finger relationship: proximally_connected_to UBERON:0004323 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 5 [Term] id: UBERON:0004315 name: distal phalanx of pedal digit 1 def: "A distal phalanx that is part of a foot digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "distal phalanx of foot digit 1" EXACT [OBOL:automatic] synonym: "distal phalanx of hallux" EXACT [OBOL:automatic] synonym: "foot digit 1 distal phalanx" EXACT [OBOL:automatic] synonym: "hallux distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of big toe" EXACT [FMA:32627] synonym: "distal phalanx of first digit of foot" EXACT [FMA:32627] synonym: "distal phalanx of great toe" EXACT [FMA:32627] synonym: "first distal phalanx of foot" EXACT [FMA:32627] xref: FMA:32627 ! distal phalanx of big toe intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003631 ! part_of pedal digit 1 xref: SCTID:361799003 ! Entire distal phalanx of great toe relationship: proximally_connected_to UBERON:0004332 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! proximal phalanx of pedal digit 1 [Term] id: UBERON:0004316 name: distal phalanx of pedal digit 2 def: "A distal phalanx that is part of a foot digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "2nd toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "distal phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "foot digit 2 distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of second toe" EXACT [FMA:32628] synonym: "distal phalanx of second digit of foot" EXACT [FMA:32628] synonym: "second distal phalanx of foot" EXACT [FMA:32628] xref: FMA:32628 ! distal phalanx of second toe intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003632 ! part_of pedal digit 2 xref: SCTID:361801000 ! Entire distal phalanx of second toe relationship: proximally_connected_to UBERON:0004324 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 2 [Term] id: UBERON:0004317 name: distal phalanx of pedal digit 3 def: "A distal phalanx that is part of a foot digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "3rd toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "distal phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "foot digit 3 distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of third toe" EXACT [FMA:32629] synonym: "distal phalanx of third digit of foot" EXACT [FMA:32629] synonym: "third distal phalanx of foot" EXACT [FMA:32629] xref: FMA:32629 ! distal phalanx of third toe intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003633 ! part_of pedal digit 3 xref: SCTID:361803002 ! Entire distal phalanx of third toe relationship: proximally_connected_to UBERON:0004325 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 3 [Term] id: UBERON:0004318 name: distal phalanx of pedal digit 4 def: "A distal phalanx that is part of a foot digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "4th toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "distal phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "foot digit 4 distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of fourth toe" EXACT [FMA:32630] synonym: "distal phalanx of fourth digit of foot" EXACT [FMA:32630] synonym: "fourth distal phalanx of foot" EXACT [FMA:32630] xref: FMA:32630 ! distal phalanx of fourth toe intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003634 ! part_of pedal digit 4 xref: SCTID:361805009 ! Entire distal phalanx of fourth toe relationship: proximally_connected_to UBERON:0004326 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 4 [Term] id: UBERON:0004319 name: distal phalanx of pedal digit 5 def: "A distal phalanx that is part of a foot digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "5th toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "distal phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "foot digit 5 distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of little toe" EXACT [FMA:32631] synonym: "distal phalanx of fifth digit of foot" EXACT [FMA:32631] synonym: "distal phalanx of fifth toe" EXACT [FMA:32631] synonym: "fifth distal phalanx of foot" EXACT [FMA:32631] xref: FMA:32631 ! distal phalanx of little toe intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003635 ! part_of pedal digit 5 xref: SCTID:10770001 ! Structure of distal phalanx of little toe xref: SCTID:244674003 ! Entire distal phalanx of lesser toe relationship: proximally_connected_to UBERON:0004327 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 5 [Term] id: UBERON:0004320 name: middle phalanx of manual digit 2 def: "A middle phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "2nd digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "2nd digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "2nd finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "2nd finger middle phalanx" EXACT [OBOL:automatic] synonym: "hand digit 2 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 2 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 2" EXACT [OBOL:automatic] synonym: "intermediate phalanx of second finger" EXACT [OBOL:automatic] synonym: "middle phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "middle phalanx of second finger" EXACT [OBOL:automatic] synonym: "second finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "second finger middle phalanx" EXACT [OBOL:automatic] synonym: "middle phalanx of index finger" EXACT [FMA:23933] synonym: "middle phalanx of second digit of hand" EXACT [FMA:23933] synonym: "second middle phalanx of hand" EXACT [FMA:23933] xref: FMA:23933 ! middle phalanx of index finger intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003622 ! part_of manual digit 2 xref: SCTID:263407002 ! Entire middle phalanx of index finger relationship: distally_connected_to UBERON:0004311 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of manual digit 2 relationship: proximally_connected_to UBERON:0004328 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of manual digit 2 [Term] id: UBERON:0004321 name: middle phalanx of manual digit 3 def: "A middle phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "3rd digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "3rd digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "3rd finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "3rd finger middle phalanx" EXACT [OBOL:automatic] synonym: "hand digit 3 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 3 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 3" EXACT [OBOL:automatic] synonym: "intermediate phalanx of third finger" EXACT [OBOL:automatic] synonym: "middle phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "middle phalanx of third finger" EXACT [OBOL:automatic] synonym: "middle phalanx of middle finger" EXACT [OBOL:automatic] synonym: "third finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "third finger middle phalanx" EXACT [OBOL:automatic] synonym: "middle phalanx of third digit of hand" EXACT [FMA:23934] synonym: "third middle phalanx of hand" EXACT [FMA:23934] xref: FMA:23934 ! middle phalanx of middle finger intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003623 ! part_of manual digit 3 xref: SCTID:263408007 ! Entire middle phalanx of middle finger relationship: distally_connected_to UBERON:0004312 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of manual digit 3 relationship: proximally_connected_to UBERON:0004329 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of manual digit 3 [Term] id: UBERON:0004322 name: middle phalanx of manual digit 4 def: "A middle phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "4th digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "4th digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "4th finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "4th finger middle phalanx" EXACT [OBOL:automatic] synonym: "fourth finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "fourth finger middle phalanx" EXACT [OBOL:automatic] synonym: "hand digit 4 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 4 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 4" EXACT [OBOL:automatic] synonym: "middle phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "middle phalanx of ring finger" EXACT [OBOL:automatic] synonym: "middle phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "fourth middle phalanx of hand" EXACT [FMA:23935] synonym: "middle phalanx of fourth digit of hand" EXACT [FMA:23935] xref: FMA:23935 ! middle phalanx of ring finger intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003624 ! part_of manual digit 4 xref: SCTID:263409004 ! Entire middle phalanx of ring finger relationship: distally_connected_to UBERON:0004313 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of manual digit 4 relationship: proximally_connected_to UBERON:0004330 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of manual digit 4 [Term] id: UBERON:0004323 name: middle phalanx of manual digit 5 def: "A middle phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "5th digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "5th digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "5th finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "5th finger middle phalanx" EXACT [OBOL:automatic] synonym: "fifth finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "fifth finger middle phalanx" EXACT [OBOL:automatic] synonym: "hand digit 5 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 5 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 5" EXACT [OBOL:automatic] synonym: "middle phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "middle phalanx of little finger" EXACT [OBOL:automatic] synonym: "middle phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "fifth middle phalanx of hand" EXACT [FMA:23936] synonym: "middle phalanx of fifth digit of hand" EXACT [FMA:23936] xref: FMA:23936 ! middle phalanx of little finger intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003625 ! part_of manual digit 5 xref: SCTID:263410009 ! Entire middle phalanx of little finger relationship: distally_connected_to UBERON:0004314 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of manual digit 5 relationship: proximally_connected_to UBERON:0004331 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of manual digit 5 [Term] id: UBERON:0004324 name: middle phalanx of pedal digit 2 def: "A middle phalanx that is part of a foot digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "2nd toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "2nd toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 2 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 2 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "middle phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "middle phalanx of second toe" EXACT [FMA:32623] synonym: "middle phalanx of second digit of foot" EXACT [FMA:32623] synonym: "second middle phalanx of foot" EXACT [FMA:32623] xref: FMA:32623 ! middle phalanx of second toe intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003632 ! part_of pedal digit 2 xref: SCTID:182152006 ! Entire middle phalanx of second toe relationship: distally_connected_to UBERON:0004316 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of pedal digit 2 relationship: proximally_connected_to UBERON:0004333 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of pedal digit 2 [Term] id: UBERON:0004325 name: middle phalanx of pedal digit 3 def: "A middle phalanx that is part of a foot digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "3rd toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "3rd toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 3 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 3 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "middle phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "middle phalanx of third toe" EXACT [FMA:32624] synonym: "middle phalanx of third digit of foot" EXACT [FMA:32624] synonym: "third middle phalanx of foot" EXACT [FMA:32624] xref: FMA:32624 ! middle phalanx of third toe intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003633 ! part_of pedal digit 3 xref: SCTID:182154007 ! Entire middle phalanx of third toe relationship: distally_connected_to UBERON:0004317 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of pedal digit 3 relationship: proximally_connected_to UBERON:0004334 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of pedal digit 3 [Term] id: UBERON:0004326 name: middle phalanx of pedal digit 4 def: "A middle phalanx that is part of a pedal digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "4th toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "4th toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 4 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 4 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "middle phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "middle phalanx of fourth toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "fourth middle phalanx of foot" EXACT [FMA:32625] synonym: "middle phalanx of fourth digit of foot" EXACT [FMA:32625] xref: FMA:32625 ! middle phalanx of foot digit 4 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003634 ! part_of pedal digit 4 xref: SCTID:182156009 ! Entire middle phalanx of fourth toe relationship: distally_connected_to UBERON:0004318 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of pedal digit 4 relationship: proximally_connected_to UBERON:0004335 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of pedal digit 4 [Term] id: UBERON:0004327 name: middle phalanx of pedal digit 5 def: "A middle phalanx that is part of a pedal digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "5th toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "5th toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 5 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 5 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "middle phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "middle phalanx of little toe" EXACT [OBOL:automatic] xref: FMA:230984 ! middle phalanx of little toe intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003635 ! part_of pedal digit 5 xref: SCTID:182158005 ! Entire middle phalanx of little toe xref: SCTID:244673009 ! Entire middle phalanx of lesser toe relationship: distally_connected_to UBERON:0004319 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! distal phalanx of pedal digit 5 relationship: proximally_connected_to UBERON:0004336 {gci_relation="part_of", gci_filler="NCBITaxon:314146", source="shoge-lite"} ! proximal phalanx of pedal digit 5 [Term] id: UBERON:0004338 name: proximal phalanx of manual digit 1 def: "A proximal phalanx that is part of a hand digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "proximal phalanx of thumb" EXACT [OBOL:automatic] synonym: "thumb proximal" EXACT [OBOL:automatic] synonym: "first proximal phalanx of hand" EXACT [FMA:23918] synonym: "proximal phalanx of first digit of hand" EXACT [FMA:23918] xref: FMA:23918 ! proximal phalanx of thumb intersection_of: UBERON:0004302 intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: proximally_connected_to UBERON:0003645 ! metacarpal bone of digit 1 xref: SCTID:181992006 ! Entire proximal phalanx of thumb [Term] id: UBERON:0004328 name: proximal phalanx of manual digit 2 def: "A proximal phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "2nd digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "2nd finger proximal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 2 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of second finger" EXACT [OBOL:automatic] synonym: "second finger proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of index finger" EXACT [FMA:23919] synonym: "proximal phalanx of second digit of hand" EXACT [FMA:23919] synonym: "second proximal phalanx of hand" EXACT [FMA:23919] xref: FMA:23919 ! proximal phalanx of index finger intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003622 ! part_of manual digit 2 relationship: proximally_connected_to UBERON:0003646 ! metacarpal bone of digit 2 xref: SCTID:263403003 ! Entire proximal phalanx of index finger [Term] id: UBERON:0004329 name: proximal phalanx of manual digit 3 def: "A proximal phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "3rd digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "3rd finger proximal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 3 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of third finger" EXACT [OBOL:automatic] synonym: "third finger proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of middle finger" EXACT [FMA:23920] synonym: "proximal phalanx of third digit of hand" EXACT [FMA:23920] synonym: "third proximal phalanx of hand" EXACT [FMA:23920] xref: FMA:23920 ! proximal phalanx of middle finger intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003623 ! part_of manual digit 3 relationship: proximally_connected_to UBERON:0003647 ! metacarpal bone of digit 3 xref: SCTID:263404009 ! Entire proximal phalanx of middle finger [Term] id: UBERON:0004330 name: proximal phalanx of manual digit 4 def: "A proximal phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "4th digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "4th finger proximal phalanx" EXACT [OBOL:automatic] synonym: "fourth finger proximal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 4 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of ring finger" EXACT [FMA:23921] synonym: "fourth proximal phalanx of hand" EXACT [FMA:23921] synonym: "proximal phalanx of fourth digit of hand" EXACT [FMA:23921] xref: FMA:23921 ! proximal phalanx of ring finger intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003624 ! part_of manual digit 4 relationship: proximally_connected_to UBERON:0003648 ! metacarpal bone of digit 4 xref: SCTID:263405005 ! Entire proximal phalanx of ring finger [Term] id: UBERON:0004331 name: proximal phalanx of manual digit 5 def: "A proximal phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "5th digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "5th finger proximal phalanx" EXACT [OBOL:automatic] synonym: "fifth finger proximal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 5 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of little finger" EXACT [FMA:23922] synonym: "fifth proximal phalanx of hand" EXACT [FMA:23922] synonym: "proximal phalanx of fifth digit of hand" EXACT [FMA:23922] xref: FMA:23922 ! proximal phalanx of little finger intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003625 ! part_of manual digit 5 relationship: proximally_connected_to UBERON:0003649 ! metacarpal bone of digit 5 xref: SCTID:263406006 ! Entire proximal phalanx of little finger [Term] id: UBERON:0004332 name: proximal phalanx of pedal digit 1 def: "A proximal phalanx that is part of a pedal digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit 1 proximal phalanx" EXACT [OBOL:automatic] synonym: "hallux proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 1" EXACT [OBOL:automatic] synonym: "proximal phalanx of hallux" EXACT [OBOL:automatic] synonym: "proximal phalanx of big toe" EXACT [FMA:43252] synonym: "proximal phalanx of great toe" EXACT [FMA:43252] synonym: "proximal phalanx of the 1st toe" EXACT [] xref: FMA:43252 ! proximal phalanx of big toe intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003631 ! part_of pedal digit 1 relationship: proximally_connected_to UBERON:0003650 ! metatarsal bone of digit 1 xref: SCTID:182150003 ! Entire proximal phalanx of great toe [Term] id: UBERON:0004333 name: proximal phalanx of pedal digit 2 def: "A proximal phalanx that is part of a pedal digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "2nd toe proximal phalanx" EXACT [OBOL:automatic] synonym: "foot digit 2 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "proximal phalanx of second toe" EXACT [FMA:32618] synonym: "proximal phalanx of second digit of foot" EXACT [FMA:32618] synonym: "second proximal phalanx of foot" EXACT [FMA:32618] synonym: "proximal phalanx of the 2nd toe" EXACT [] xref: FMA:32618 ! proximal phalanx of second toe intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003632 ! part_of pedal digit 2 relationship: proximally_connected_to UBERON:0003651 ! metatarsal bone of digit 2 xref: SCTID:182151004 ! Entire proximal phalanx of second toe [Term] id: UBERON:0004334 name: proximal phalanx of pedal digit 3 def: "A proximal phalanx that is part of a pedal digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "3rd toe proximal phalanx" EXACT [OBOL:automatic] synonym: "foot digit 3 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "proximal phalanx of third toe" EXACT [FMA:32619] synonym: "proximal phalanx of third digit of foot" EXACT [FMA:32619] synonym: "third proximal phalanx of foot" EXACT [FMA:32619] synonym: "proximal phalanx of the 3rd toe" EXACT [] xref: FMA:32619 ! proximal phalanx of third toe intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003633 ! part_of pedal digit 3 relationship: proximally_connected_to UBERON:0003652 ! metatarsal bone of digit 3 xref: SCTID:182153001 ! Entire proximal phalanx of third toe [Term] id: UBERON:0004335 name: proximal phalanx of pedal digit 4 def: "A proximal phalanx that is part of a pedal digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "4th toe proximal phalanx" EXACT [OBOL:automatic] synonym: "foot digit 4 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "proximal phalanx of fourth toe" EXACT [FMA:32620] synonym: "fourth proximal phalanx of foot" EXACT [FMA:32620] synonym: "proximal phalanx of fourth digit of foot" EXACT [FMA:32620] synonym: "proximal phalanx of the 4th toe" EXACT [] xref: FMA:32620 ! proximal phalanx of fourth toe intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003634 ! part_of pedal digit 4 relationship: proximally_connected_to UBERON:0003653 ! metatarsal bone of digit 4 xref: SCTID:182155008 ! Entire proximal phalanx of fourth toe [Term] id: UBERON:0004336 name: proximal phalanx of pedal digit 5 def: "A proximal phalanx that is part of a pedal digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "5th toe proximal phalanx" EXACT [OBOL:automatic] synonym: "foot digit 5 proximal phalanx" EXACT [OBOL:automatic] synonym: "proximal phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of little toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "fifth proximal phalanx of foot" EXACT [FMA:32621] synonym: "proximal phalanx of fifth digit of foot" EXACT [FMA:32621] synonym: "proximal phalanx of fifth toe" EXACT [FMA:32621] synonym: "proximal phalanx of the 5th toe" EXACT [] xref: FMA:32621 ! proximal phalanx of little toe intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003635 ! part_of pedal digit 5 relationship: proximally_connected_to UBERON:0003654 ! metatarsal bone of digit 5 xref: SCTID:182157000 ! Entire proximal phalanx of little toe xref: SCTID:244672004 ! Entire proximal phalanx of lesser toe [Term] id: UBERON:0004340 ! allantois name: allantois def: "A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]." [VHOG:0000738, Wikipedia:Allantois] comment: a diverticulum of the hindgut endoderm [ISBN10:0073040584 "Vertebrates\, Kardong"]. AO notes: part_of embryo in EHDAA2 - note differences in humans xref: EMAPA:28547 ! allantois of urinary system xref: EMAPA:16107 ! allantois of extraembryonic component xref: EMAPA:16084 ! allantois xref: ncithesaurus:Allantois ! Allantois xref: BTO:0000474 ! allantois xref: VHOG:0000738 ! allantois xref: EHDAA2:0000113 ! allantois xref: RETIRED_EHDAA2:0000114 ! allantois xref: MESH:A16.254.403.147 ! allantoi is_a: UBERON:0005631 ! extraembryonic membrane relationship: develops_from UBERON:0004872 {source="ISBN10:0073040584"} ! splanchnic layer of lateral plate mesoderm relationship: develops_from UBERON:0000925 {source="ISBN10:0073040584", notes="hindgut diverticulum endoderm"} ! endoderm relationship: develops_from UBERON:0001040 {source="EHDAA2"} ! yolk sac relationship: overlaps UBERON:0001008 {source="EHDAA2-modified"} ! excretory system xref: SCTID:308825007 ! Entire allantois xref: http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray25.png property_value: external_definition "A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000738", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/allantois", source="http://bgee.unil.ch/"} property_value: homology_notes "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {external_class="VHOG:0000738", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.187", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: has_relational_adjective "allantoic" xsd:string xref: UMLS:C0002084 [Term] id: UBERON:0004346 ! gubernaculum name: gubernaculum alt_id: UBERON:0000452 def: "embryonic structures which begin as undifferentiated mesenchyme attaching to the caudal end of the gonads. The gubernaculum is present only during the development of the urinary and reproductive organs, being replaced by distinct vestiges in males and females[WP]. Enitoinguinal ligaments that, in the male, connect the fetal testis to the developing scrotum, and, in the female, connect the ovaries to the uterus[MP]" [Wikipedia:Gubernaculum, MP:0005149] comment: WP def is male/female, split term? EMAP is male-specific. vestigial adult in FMA. TODO synonym: "gubernaculae" RELATED PLURAL [] synonym: "gubernaculum testis" NARROW [] synonym: "caudal suspensory ligament" RELATED [EMAPA:19089] is_a: UBERON:0003104 {source="Wikipedia"} ! mesenchyme is_a: UBERON:0006590 {source="FMA"} ! vestigial embryonic structure relationship: part_of UBERON:0000990 ! reproductive system relationship: part_of UBERON:0002358 ! peritoneum relationship: part_of UBERON:0000323 {source="BTO"} ! late embryo relationship: attaches_to UBERON:0000991 ! gonad relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm xref: ncithesaurus:Gubernaculum_Testis ! Gubernaculum Testis synonym: "Gabernaculum" RELATED LATIN [Wikipedia:Gubernaculum] xref: http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1138.png property_value: has_relational_adjective "gubernacular" xsd:string xref: UMLS:C0228051 [Term] id: UBERON:0008843 name: gubernaculum testis def: "The fetal ligament attached to the inferior end of the epididymis and testis and, at its other end, to the bottom of the scrotum; it is present during, and is thought to guide, the descent of the testis into the scrotum and then atrophies." [BTO:0002813] comment: The upper part of the gubernaculum degenerates; The lower part persists as the gubernaculum testis ("scrotal ligament"). This ligament secures the testis to the most inferior portion of the scrotum, tethering it in place and limiting the degree to which the testis can move within the scrotum[WP] synonym: "Hunter's gubernaculum" RELATED [BTO:0002813] xref: BTO:0002813 ! gubernaculum testis xref: EMAPA:19089 ! gubernaculum xref: FMA:20421 ! Gubernaculum testis intersection_of: UBERON:0004346 ! gubernaculum intersection_of: part_of UBERON:0000079 ! male reproductive system xref: SCTID:299983007 ! Entire gubernaculum testis [Term] id: UBERON:0008844 name: gubernaculum (female) comment: The upper part of the gubernaculum, together with the ovarian artery and vein form the suspensory ligament of the ovary,[1] which suspends the ovary from the pelvic wall.; The lower gubernaculum has two vestigial remnants in females, the ovarian ligament and the round ligament of the uterus (ligamentum teres uteri) which respectively serve to support the ovaries and uterus in the pelvis intersection_of: UBERON:0004346 ! gubernaculum intersection_of: part_of UBERON:0000474 ! female reproductive system def: "A gubernaculum that is part of a female reproductive system." [OBOL:automatic] [Term] id: UBERON:0008842 name: suspensory ligament of testis def: "The cranial atrophic portion of the urogenital ridge attached to the cranial pole of the intraabdominal embryonic testis" [http://www.medilexicon.com/medicaldictionary.php?t=49790, Wikipedia:Scrotal_ligament] is_a: UBERON:0008841 {source="Obol"} ! suspensory ligament intersection_of: UBERON:0008841 ! suspensory ligament intersection_of: attaches_to UBERON:0000473 ! testis relationship: part_of UBERON:0004876 {source="Obol"} ! urogenital ridge [Term] id: UBERON:0008848 name: cranial suspensory ligament comment: todo - check - add cranial ovarian susp ligaments def: "Connects the cranial tip of the future gonad to the dorsocranial abdominal cavity." [] is_a: UBERON:0008841 {source="Obol"} ! suspensory ligament relationship: part_of UBERON:0003135 {source="EMAPA"} ! male reproductive organ xref: EMAPA:30068 ! cranial suspensory ligament [Term] id: UBERON:0006594 name: chorda gubernaculum def: "A portion of the gubernaculum testis and round ligament that develops in the body wall of the embryo." [Dorlands_Medical_Dictionary:MerckSource] synonym: "gubernacular cord" RELATED [] synonym: "plica gubernaculi" RELATED [PMID:11997885] xref: BTO:0002814 ! chorda gubernaculum is_a: UBERON:0006590 ! vestigial embryonic structure relationship: part_of UBERON:0008843 ! gubernaculum testis [Term] id: UBERON:0012326 ! gubernacular bulb name: gubernacular bulb comment: Hrabovszky et al propose the bulb is the growing end of the elongating gubernaculum, analogous to the growth of a limb bud[PMID:11997885] synonym: "pars infravaginalis gubernaculi" NARROW [PMID:11997885] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0008843 ! gubernaculum testis [Term] id: UBERON:0004348 name: optic eminence def: "the embryonic structure that gives rise to the corneal ectoderm" [MP:0006305] xref: EMAPA:17003 ! surface ectoderm of the eye xref: EMAPA:16322 ! optic eminence xref: VHOG:0001296 ! optic eminence xref: RETIRED_EHDAA2:0001308 ! optic eminence xref: EHDAA:938 ! optic eminence is_a: UBERON:0000061 ! anatomical structure relationship: develops_into UBERON:0000964 ! cornea [Term] id: UBERON:0005879 ! pharyngeal cleft name: pharyngeal cleft def: "the counterpart of a branchial pouch on the ectodermal side. The first pharyngeal groove produces the external auditory meatus.[2] The rest (2, 3, and 4) are overlapped by the growing 2nd pharyngeal arch, and form the floor of the depression termed the cervical sinus, which opens ventrally, and finally obliterated[WP]." [Wikipedia:Pharyngeal_groove] comment: AO notes: some ontologies distringuish between cleft and cleft ectoderm, we merge these here. Editor notes: consider adding location (precursor) - i.e. external (ectodermal). Note we use overlaps as the relationship to the arches xref: AAO:0010623 ! pharyngeal cleft synonym: "branchial groove" RELATED [AAO:0010623, Wikipedia:Pharyngeal_groove] synonym: "branchial cleft" RELATED [Wikipedia:Pharyngeal_groove] synonym: "gill cleft" NARROW [] synonym: "Kiemenspalten" RELATED [] synonym: "pharyngeal groove" EXACT [Wikipedia:Pharyngeal_groove] synonym: "pharyngeal groove ectoderm" EXACT [UBERON:cjm] synonym: "sulcus pharyngei" RELATED LATIN [Wikipedia:Pharyngeal_groove] is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0006846 {source="EHDAA2"} ! groove relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0000922 ! embryo relationship: overlaps UBERON:0002539 ! pharyngeal arch xref: ncithesaurus:Pharyngeal_Groove ! Pharyngeal Groove xref: http://upload.wikimedia.org/wikipedia/commons/2/20/Kiemenbogen.jpg xref: UMLS:C1280559 [Term] id: UBERON:0013157 name: 1st arch maxillary-mandibular cleft is_a: UBERON:0005879 ! pharyngeal cleft relationship: part_of UBERON:0004362 {source="EHDAA2"} ! pharyngeal arch 1 relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm xref: EHDAA2:0000046 ! 1st arch maxillary-mandibular groove ectoderm xref: EMAPA:16395 ! ectoderm of maxillary-mandibular groove synonym: "1st arch maxillary-mandibular groove ectoderm" EXACT [EHDAA2:0000046] synonym: "ectoderm of maxillary-mandibular groove" EXACT [EMAPA:16395] [Term] id: UBERON:0005872 ! 1st arch pharyngeal cleft name: 1st arch pharyngeal cleft def: "A groove that is situated between the 1st and 2nd pharyngeal arch." [VHOG:OG] subset: vertebrate_core synonym: "1st arch branchial groove" EXACT [EHDAA2:0000008] synonym: "branchial groove of 1st arch" EXACT [EMAPA:16119] synonym: "1st arch groove ectoderm" EXACT [EHDAA2:0000009] xref: EHDAA2:0000009 ! 1st arch groove ectoderm xref: EMAPA:16119 ! branchial groove of 1st arch xref: EHDAA:575 ! branchial groove xref: VHOG:0000969 ! 1st arch branchial groove xref: VHOG:0000554 ! 1st pharyngeal groove ectoderm intersection_of: UBERON:0005879 ! pharyngeal cleft intersection_of: overlaps UBERON:0004362 ! pharyngeal arch 1 intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 synonym: "1st pharyngeal groove" EXACT [VHOG:0000969] synonym: "1st pharyngeal cleft" RELATED [VHOG:0000969] synonym: "1st pharyngeal groove ectoderm" EXACT [VHOG:0000554] property_value: external_definition "A groove that is situated between the 1st and 2nd pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.70, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000969", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In all jawed vertebrates the first arch forms the jaw, while the second arch forms the hyoid apparatus. These two arches are separated by the first pharyngeal pouch and cleft.[well established][VHOG]" xsd:string {external_class="VHOG:0000969", ontology="VHOG", source="DOI:10.1016/j.semcdb.2010.01.022 Grevellec A\, Tucker AS\, The pharyngeal pouches and clefts: development\, evolution\, structure and derivatives. Seminars in Cell and Developmental Biology (2010)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005873 name: 2nd arch pharyngeal cleft def: "A groove that is situated between the 2nd and 3rd pharyngeal arch." [VHOG:OG] subset: vertebrate_core synonym: "2nd arch branchial groove" EXACT [EHDAA2:0000054] synonym: "branchial groove of 2nd arch" EXACT [EMAPA:16396] synonym: "2nd arch groove ectoderm" EXACT [EHDAA2:0000057] xref: EHDAA2:0000057 ! 2nd arch groove ectoderm xref: EMAPA:16396 ! branchial groove of 2nd arch xref: EHDAA:613 ! branchial groove xref: VHOG:0000972 ! 2nd arch branchial groove xref: VHOG:0000568 ! 2nd pharyngeal groove ectoderm intersection_of: UBERON:0005879 ! pharyngeal cleft intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 synonym: "2nd pharyngeal groove" EXACT [VHOG:0000972] synonym: "2nd pharyngeal cleft" RELATED [VHOG:0000972] synonym: "2nd pharyngeal groove ectoderm" EXACT [VHOG:0000568] property_value: external_definition "A groove that is situated between the 2nd and 3rd pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.70, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000972", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005874 name: 3rd arch pharyngeal cleft def: "A groove that is situated between the 3rd and 4th pharyngeal arch." [VHOG:OG] subset: vertebrate_core synonym: "3rd arch branchial groove" EXACT [EHDAA2:0000071] synonym: "branchial groove of 3rd arch" EXACT [EMAPA:16581] synonym: "3rd arch groove ectoderm" EXACT [EHDAA2:0000074] xref: EHDAA2:0000074 ! 3rd arch groove ectoderm xref: EMAPA:16581 ! branchial groove of 3rd arch xref: EHDAA:1082 ! branchial groove xref: VHOG:0000973 ! 3rd arch branchial groove xref: VHOG:0000572 ! 3rd pharyngeal groove ectoderm intersection_of: UBERON:0005879 ! pharyngeal cleft intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 intersection_of: overlaps UBERON:0003115 ! pharyngeal arch 4 synonym: "3rd pharyngeal groove" EXACT [VHOG:0000973] synonym: "3rd pharyngeal cleft" RELATED [VHOG:0000973] synonym: "3rd pharyngeal groove ectoderm" EXACT [VHOG:0000572] property_value: external_definition "A groove that is situated between the 3rd and 4th pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.70, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000973", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005875 name: 4th arch pharyngeal cleft def: "A groove that is situated between the 4th and 5th pharyngeal arch." [VHOG:OG] subset: vertebrate_core synonym: "4th arch branchial groove" EXACT [RETIRED_EHDAA2:0000088] synonym: "branchial groove of 4th arch" EXACT [EMAPA:16761] synonym: "4th arch pharyngeal groove ectoderm" EXACT [EHDAA2:0000089] xref: RETIRED_EHDAA2:0000088 ! 4th arch branchial groove xref: EHDAA2:0000089 ! 4th arch pharyngeal groove ectoderm xref: EMAPA:16761 ! branchial groove of 4th arch xref: EMAPA:16762 ! ectoderm of branchial groove of 4th arch xref: EHDAA:1665 ! branchial groove xref: VHOG:0000968 ! 4th arch branchial groove xref: VHOG:0000577 ! 4th pharyngeal groove ectoderm intersection_of: UBERON:0005879 ! pharyngeal cleft intersection_of: overlaps UBERON:0003115 ! pharyngeal arch 4 intersection_of: overlaps UBERON:0003116 ! pharyngeal arch 5 synonym: "4th pharyngeal groove" EXACT [VHOG:0000968] synonym: "4th pharyngeal cleft" RELATED [VHOG:0000968] synonym: "4th pharyngeal groove ectoderm" EXACT [VHOG:0000577] property_value: external_definition "A groove that is situated between the 4th and 5th pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.70, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000968", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004117 name: pharyngeal pouch def: "embryonic structure that forms on the endodermal side between the pharyngeal arches, and pharyngeal grooves (or clefts) form the lateral ectodermal surface of the neck region to separate the arches. The pouches line up with the clefts, and these thin segments become gills in fish[WP]. Outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits[ZFA]." [Wikipedia:Pharyngeal_pouch_(embryology)] comment: AO notes: VHOG and EMAPAA distinguish between pouch endoderm and pouch but we merge those here. Editor notes: consider adding location (precursor) - i.e. internal (endodermal) // The pouches are polarized structures. For example, whereas the rostral half of each pouch expresses Bmp-7, the caudal half expresses FGF-8 and the dorsal aspect of each pouch is marked via its expression of Pax-1. each pouch has an individual sense of identity. Shh expression is a prominent early feature of the caudal endoderm of the second arch, and individual pouches mark the anterior limits of expression of Hox genes within the pharyngeal endoderm; Hox-a2 has a rostral boundary at the second pouch, Hox-a3 at the third pouch and Hox-a4 at the most caudal pouch[PMID:16313389] subset: vertebrate_core synonym: "branchial pouch" EXACT [Wikipedia:Branchial_pouch] synonym: "visceral pouch" EXACT SENSU [] xref: ZFA:0001106 ! pharyngeal pouch xref: VHOG:0001203 ! pharyngeal pouch xref: EHDAA:1086 ! branchial pouch xref: EHDAA:1669 ! branchial pouch xref: EHDAA:579 ! branchial pouch xref: EHDAA:617 ! branchial pouch xref: ncithesaurus:Pharyngeal_Pouch ! Pharyngeal Pouch xref: XAO:0000282 ! visceral pouch xref: EFO:0003627 ! pharyngeal pouch is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0008814 ! pharyngeal system relationship: overlaps UBERON:0002539 ! pharyngeal arch relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata relationship: develops_from UBERON:0007690 {source="ZFA", source="EHDAA2"} ! early pharyngeal endoderm xref: AAO:0011113 ! visceral pouch xref: SCTID:34674002 ! Pharyngeal pouch xref: TAO:0001106 ! pharyngeal pouch property_value: external_definition "Outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits. Crump et al, 2004.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001106", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "pharyngeal pouches" RELATED [VHOG:0001203] synonym: "visceral pouches" RELATED [VHOG:0001203] property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0001203", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M\, Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231067 [Term] id: UBERON:0007122 alt_id: UBERON:0005718 name: pharyngeal pouch 1 def: "The endoderm lines the future auditory tube (Pharyngotympanic Eustachian tube) , middle ear, mastoid antrum, and inner layer of the tympanic membrane. & origin of Mandibular nerve & Maxillary artery[WP]. The first pouch lies between the first and second arches[PMID]" [Wikipedia:Pharyngeal_pouch_(embryology)#First_pouch, PMID:16313389] comment: we use adjacency relations rather than part_of, as in EHDAA2 subset: vertebrate_core synonym: "first visceral pouch" EXACT [XAO:0000102] synonym: "pharyngeal pouches 1" EXACT PLURAL [ZFA:0001128] synonym: "visceral pouch 1" EXACT [XAO:0000102] synonym: "first arch pharyngeal pouch" EXACT [OBOL:automatic] synonym: "1st branchial pouch" EXACT [] synonym: "1st arch branchial pouch" EXACT [EHDAA2:0000013] synonym: "1st arch pouch endoderm" EXACT [EHDAA2:0000016] synonym: "1st arch branchial pouch endoderm" EXACT [EHDAA2:0000016] synonym: "hyomandibular pouch" EXACT [] xref: XAO:0000102 ! visceral pouch 1 xref: ZFA:0001128 ! pharyngeal pouch 1 xref: VHOG:0000970 ! first pharyngeal pouch xref: VHOG:0000555 ! 1st pharyngeal pouch endoderm xref: EFO:0003631 ! pharyngeal pouch 1 xref: EHDAA2:0000016 ! 1st arch branchial pouch endoderm xref: EMAPA:16124 ! branchial pouch of 1st arch xref: EMAPA:16124 ! branchial pouch of 1st arch intersection_of: UBERON:0004117 ! pharyngeal pouch intersection_of: overlaps UBERON:0004362 ! pharyngeal arch 1 intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 xref: ncithesaurus:First_Pharyngeal_Pouch ! First Pharyngeal Pouch xref: AAO:0011114 ! visceral pouch 1 xref: SCTID:345248006 ! Entire first pharyngeal pouch xref: TAO:0001128 ! pharyngeal pouch 1 property_value: external_definition "First of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011114", date_retrieved="2012-06-20", source="ISBN:0-226-55763-4"} synonym: "first pharyngeal pouch" RELATED [VHOG:0000970] synonym: "1st pharyngeal pouch endoderm" EXACT [VHOG:0000555] property_value: external_definition "A pouch that is situated between the 1st and 2nd pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.72, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000970", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In all jawed vertebrates the first arch forms the jaw, while the second arch forms the hyoid apparatus. These two arches are separated by the first pharyngeal pouch and cleft.[well established][VHOG]" xsd:string {external_class="VHOG:0000970", ontology="VHOG", source="DOI:10.1016/j.semcdb.2010.01.022 Grevellec A\, Tucker AS\, The pharyngeal pouches and clefts: development\, evolution\, structure and derivatives. Seminars in Cell and Developmental Biology (2010)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231068 [Term] id: UBERON:0007123 alt_id: UBERON:0005715 name: pharyngeal pouch 2 def: "The second pouch between the second and third arches. Contributes to the middle ear, epithelial lining of Crypts (spaces) of the palatine tonsils, supplied by the facial nerve[WP]" [Wikipedia:Pharyngeal_pouch_(embryology)#Second_pouch, PMID:16313389] subset: vertebrate_core synonym: "pharyngeal pouches 2" EXACT PLURAL [ZFA:0001130] synonym: "second visceral pouch" EXACT [XAO:0000247] synonym: "visceral pouch 2" EXACT [XAO:0000247] synonym: "second arch pharyngeal pouch" EXACT [OBOL:automatic] synonym: "2nd branchial pouch" EXACT [] synonym: "2nd arch branchial pouch" EXACT [RETIRED_EHDAA2:0000060] synonym: "2nd arch pouch endoderm" EXACT [EHDAA2:0000058] synonym: "2nd arch branchial pouch endoderm" EXACT [EHDAA2:0000061] xref: XAO:0000247 ! visceral pouch 2 xref: ZFA:0001130 ! pharyngeal pouch 2 xref: VHOG:0000967 ! second pharyngeal pouch xref: VHOG:0000561 ! 2nd pharyngeal pouch endoderm xref: EFO:0003633 ! pharyngeal pouch 2 xref: RETIRED_EHDAA2:0000060 ! 2nd arch branchial pouch xref: EMAPA:16275 ! branchial pouch of 2nd arch xref: EMAPA:16276 ! endoderm of branchial pouch of 2nd arch xref: EHDAA2:0000058 ! 2nd arch pouch endoderm intersection_of: UBERON:0004117 ! pharyngeal pouch intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 xref: ncithesaurus:Second_Pharyngeal_Pouch ! Second Pharyngeal Pouch xref: AAO:0011115 ! visceral pouch 2 xref: SCTID:345349000 ! Entire second pharyngeal pouch xref: TAO:0001130 ! pharyngeal pouch 2 property_value: external_definition "Second of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011115", date_retrieved="2012-06-20", source="ISBN:0-226-55763-4"} synonym: "second pharyngeal pouch" RELATED [VHOG:0000967] synonym: "2nd pharyngeal pouch endoderm" EXACT [VHOG:0000561] property_value: external_definition "A pouch that is situated between the 2nd and 3rd pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.72, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000967", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0000967", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231069 [Term] id: UBERON:0007124 alt_id: UBERON:0005716 name: pharyngeal pouch 3 def: "The third pouch possesses Dorsal and Ventral wings. Derivatives of the dorsal wings include the inferior parathyroid glands, while the ventral wings fuse to form the cytoreticular cells of the thymus. The main nerve supply to the derivatives of this pouch is Cranial Nerve IX, glossopharyngeal nerve[WP]. The third pouch lies between the third and fourth arches[PMID]." [Wikipedia:Pharyngeal_pouch_(embryology)#Third_pouch, PMID:16313389] subset: vertebrate_core synonym: "pharyngeal pouches 3" EXACT PLURAL [ZFA:0001131] synonym: "third visceral pouch" EXACT [XAO:0000251] synonym: "visceral pouch 3" EXACT [XAO:0000251] synonym: "3rd branchial pouch" EXACT [] synonym: "third arch pharyngeal pouch" EXACT [OBOL:automatic] synonym: "3rd arch branchial pouch" EXACT [RETIRED_EHDAA2:0000076] synonym: "3rd arch branchial pouch endoderm" EXACT [EHDAA2:0000077] xref: XAO:0000251 ! visceral pouch 3 xref: ZFA:0001131 ! pharyngeal pouch 3 xref: EFO:0003634 ! pharyngeal pouch 3 xref: RETIRED_EHDAA2:0000076 ! 3rd arch branchial pouch xref: VHOG:0001030 ! 3rd pharyngeal pouch endoderm xref: VHOG:0000966 ! third pharyngeal pouch xref: EMAPA:16586 ! branchial pouch of 3rd arch xref: EHDAA2:0000077 ! 3rd arch branchial pouch endoderm intersection_of: UBERON:0004117 ! pharyngeal pouch intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 intersection_of: overlaps UBERON:0003115 ! pharyngeal arch 4 xref: ncithesaurus:Third_Pharyngeal_Pouch ! Third Pharyngeal Pouch xref: AAO:0011116 ! visceral pouch 3 xref: SCTID:345450001 ! Entire third pharyngeal pouch xref: TAO:0001131 ! pharyngeal pouch 3 property_value: external_definition "Third of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011116", date_retrieved="2012-06-20", source="ISBN:0-226-55763-4"} synonym: "3rd pharyngeal pouch endoderm" EXACT [VHOG:0001030] synonym: "third pharyngeal pouch" RELATED [VHOG:0000966] property_value: external_definition "A pouch that is situated between the 3rd and 4th pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.72, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000966", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0000966", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231070 [Term] id: UBERON:0007125 ! pharyngeal pouch 4 name: pharyngeal pouch 4 def: "A pouch that is situated between the 4th and 5th pharyngeal arch[Bard]. Derivatives include: superior parathyroid glands and ultimobranchial body which forms the parafollicular C-Cells of the thyroid gland. Musculature and cartilage of larynx (along with the sixth pharyngeal pouch)[WP]" [Wikipedia:Pharyngeal_pouch_(embryology)#Fourth_pouch, PMID:16313389] comment: todo - check relationships subset: vertebrate_core synonym: "pharyngeal pouches 4" EXACT PLURAL [ZFA:0001134] synonym: "fourth visceral pouch" EXACT [XAO:0000254] synonym: "4th branchial pouch" EXACT [] synonym: "visceral pouch 4" EXACT [XAO:0000254] synonym: "fourth pharyngeal pouch" RELATED [VHOG:0000971] synonym: "fourth arch pharyngeal pouch" EXACT [OBOL:automatic] synonym: "4th arch branchial pouch" EXACT [RETIRED_EHDAA2:0000090] synonym: "4th arch branchial pouch endoderm" EXACT [EHDAA2:0000091] xref: XAO:0000254 ! visceral pouch 4 xref: ZFA:0001134 ! pharyngeal pouch 4 xref: VHOG:0000971 ! fourth pharyngeal pouch xref: VHOG:0000578 ! 4th pharyngeal pouch endoderm xref: EFO:0003637 ! pharyngeal pouch 4 xref: RETIRED_EHDAA2:0000090 ! 4th arch branchial pouch xref: EMAPA:16766 ! branchial pouch of 4th arch xref: EHDAA2:0000091 ! 4th arch branchial pouch endoderm intersection_of: UBERON:0004117 ! pharyngeal pouch intersection_of: overlaps UBERON:0003115 ! pharyngeal arch 4 intersection_of: overlaps UBERON:0003116 ! pharyngeal arch 5 xref: ncithesaurus:Fourth_Pharyngeal_Pouch ! Fourth Pharyngeal Pouch xref: AAO:0011117 ! visceral pouch 4 xref: SCTID:362858001 ! Entire fourth pharyngeal pouch xref: TAO:0001134 ! pharyngeal pouch 4 property_value: external_definition "Fourth of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011117", date_retrieved="2012-06-20", source="ISBN:0-226-55763-4"} synonym: "4th pharyngeal pouch endoderm" EXACT [VHOG:0000578] property_value: external_definition "A pouch that is situated between the 4th and 5th pharyngeal arch. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.72, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000971", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0000971", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M and Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0231071 [Term] id: UBERON:0007126 ! pharyngeal pouch 5 name: pharyngeal pouch 5 def: "Rudimentary structure, becomes part of the fourth pouch contributing to thyroid C-cells[WP]." [Wikipedia:Pharyngeal_pouch_(embryology)#Fifth_pouch] comment: pouches 5 and 6 are hard to distinguish subset: vertebrate_core synonym: "pharyngeal pouches 5" EXACT PLURAL [ZFA:0001133] synonym: "fifth visceral pouch" EXACT [XAO:0000255] synonym: "5th branchial pouch" EXACT [] synonym: "visceral pouch 5" EXACT [XAO:0000255] synonym: "5th pharyngeal pouch" RELATED [VHOG:0001206] synonym: "5th visceral pouch" RELATED [VHOG:0001206] synonym: "fifth pharyngeal pouch" RELATED [VHOG:0001206] synonym: "fifth visceral pouch" RELATED [VHOG:0001206] xref: XAO:0000255 ! visceral pouch 5 xref: ZFA:0001133 ! pharyngeal pouch 5 xref: VHOG:0001206 ! fifth pharyngeal pouch xref: EFO:0003636 ! pharyngeal pouch 5 is_a: UBERON:0004117 ! pharyngeal pouch xref: ncithesaurus:Fifth_Pharyngeal_Pouch ! Fifth Pharyngeal Pouch xref: AAO:0011118 ! visceral pouch 5 xref: TAO:0001133 ! pharyngeal pouch 5 property_value: external_definition "Fifth of the pharyngeal (endodermal) evaginations between the visceral arches.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011118", date_retrieved="2012-06-20", source="ISBN:0-226-55763-4"} property_value: homology_notes "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {external_class="VHOG:0001206", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A\, Okabe M\, Quinlan R\, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1517185 [Term] id: UBERON:0007127 name: pharyngeal pouch 6 def: "Along with the fourth pouch, contributes to the formation of the musculature and cartilage of the larynx[WP]." [Wikipedia:Pharyngeal_pouch_(embryology)#Sixth_pouch] comment: pouches 5 and 6 are hard to distinguish subset: vertebrate_core synonym: "6th branchial pouch" EXACT [] synonym: "6th arch branchial pouch" EXACT [] synonym: "pharyngeal pouches 6" EXACT PLURAL [ZFA:0001132] synonym: "sixth visceral pouch" EXACT [XAO:0000265] synonym: "visceral pouch 6" EXACT [XAO:0000265] xref: XAO:0000265 ! visceral pouch 6 xref: ZFA:0001132 ! pharyngeal pouch 6 xref: EFO:0003635 ! pharyngeal pouch 6 is_a: UBERON:0004117 ! pharyngeal pouch xref: AAO:0011119 ! visceral pouch 6 xref: TAO:0001132 ! pharyngeal pouch 6 property_value: external_definition "Sixth of the pharyngeal (endodermal) evaginations between the visceral arches.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011119", date_retrieved="2012-06-20", source="ISBN:0-226-55763-4"} [Term] id: UBERON:0010021 name: dorsal part of pharyngeal pouch 1 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007122 ! pharyngeal pouch 1 comment: Development notes: in humans, dorsal diverticulum deepens as the tubotympanic recess to form the auditory tube[ISBN10:1607950324] synonym: "dorsal pharyngeal pouch 1" EXACT [] synonym: "dorsal pharyngeal pouch 1 endoderm" RELATED [] synonym: "dorsal 1st branchial pouch" EXACT [] synonym: "dorsal branchial pouch 1 endoderm" RELATED [] [Term] id: UBERON:0010022 name: ventral part of pharyngeal pouch 1 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007122 ! pharyngeal pouch 1 comment: Development notes: in humans, the ventral portion of pouches 1 and 2 are obliterated by the developing tongue[ISBN10:1607950324] synonym: "ventral pharyngeal pouch 1" EXACT [] synonym: "ventral pharyngeal pouch 1 endoderm" RELATED [] synonym: "ventral 1st branchial pouch" EXACT [] synonym: "ventral branchial pouch 1 endoderm" RELATED [] [Term] id: UBERON:0010023 name: dorsal part of pharyngeal pouch 2 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007123 ! pharyngeal pouch 2 comment: Development notes: in humans, persists as the tonsillar fossa - the endodermal lining covers the mesodermal lymphatic tissue to form the palatine tonsil[ISBN10:1607950324] synonym: "dorsal pharyngeal pouch 2" EXACT [] synonym: "dorsal pharyngeal pouch 2 endoderm" RELATED [] synonym: "dorsal 2nd branchial pouch" EXACT [] synonym: "dorsal branchial pouch 2 endoderm" RELATED [] [Term] id: UBERON:0010024 name: ventral part of pharyngeal pouch 2 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007123 ! pharyngeal pouch 2 comment: Development notes: in humans, the ventral portion of pouches 1 and 2 are obliterated by the developing tongue[ISBN10:1607950324] synonym: "ventral pharyngeal pouch 2" EXACT [] synonym: "ventral pharyngeal pouch 2 endoderm" RELATED [] synonym: "ventral 2nd branchial pouch" EXACT [] synonym: "ventral branchial pouch 2 endoderm" RELATED [] [Term] id: UBERON:0010025 name: dorsal part of pharyngeal pouch 3 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: part_of UBERON:0007124 {source="EHDAA2"} ! pharyngeal pouch 3 xref: EHDAA2:0000409 ! dorsal 3rd arch pharyngeal pouch endoderm xref: EMAPA:16758 ! dorsal synonym: "dorsal 3rd arch pharyngeal pouch endoderm" EXACT [EHDAA2:0000409] synonym: "dorsal pharyngeal pouch 3" EXACT [] synonym: "dorsal pharyngeal pouch 3 endoderm" RELATED [] synonym: "dorsal 3rd branchial pouch" EXACT [] synonym: "dorsal branchial pouch 3 endoderm" RELATED [] [Term] id: UBERON:0010026 name: ventral part of pharyngeal pouch 3 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: part_of UBERON:0007124 {source="EHDAA2"} ! pharyngeal pouch 3 xref: EHDAA2:0002173 ! ventral 3rd arch pharyngeal pouch endoderm xref: EMAPA:16759 ! ventral synonym: "ventral 3rd arch pharyngeal pouch endoderm" EXACT [EHDAA2:0002173] synonym: "ventral pharyngeal pouch 3" EXACT [] synonym: "ventral pharyngeal pouch 3 endoderm" RELATED [] synonym: "ventral 3rd branchial pouch" EXACT [] synonym: "ventral branchial pouch 3 endoderm" RELATED [] [Term] id: UBERON:0010027 name: dorsal part of pharyngeal pouch 4 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007125 ! pharyngeal pouch 4 synonym: "dorsal pharyngeal pouch 4" EXACT [] synonym: "dorsal pharyngeal pouch 4 endoderm" RELATED [] synonym: "dorsal 4th branchial pouch" EXACT [] synonym: "dorsal branchial pouch 4 endoderm" RELATED [] [Term] id: UBERON:0010028 name: ventral part of pharyngeal pouch 4 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007125 ! pharyngeal pouch 4 synonym: "ventral pharyngeal pouch 4" EXACT [] synonym: "ventral pharyngeal pouch 2 endoderm" RELATED [] synonym: "ventral 4th branchial pouch" EXACT [] synonym: "ventral branchial pouch 4 endoderm" RELATED [] [Term] id: UBERON:0010029 name: dorsal part of pharyngeal pouch 5 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007126 ! pharyngeal pouch 5 synonym: "dorsal pharyngeal pouch 5" EXACT [] synonym: "dorsal pharyngeal pouch 5 endoderm" RELATED [] synonym: "dorsal 5th branchial pouch" EXACT [] synonym: "dorsal branchial pouch 5 endoderm" RELATED [] [Term] id: UBERON:0010030 name: ventral part of pharyngeal pouch 5 is_a: UBERON:0000490 ! unilaminar epithelium relationship: part_of UBERON:0007126 ! pharyngeal pouch 5 synonym: "ventral pharyngeal pouch 5" EXACT [] synonym: "ventral pharyngeal pouch 5 endoderm" RELATED [] synonym: "ventral 5th branchial pouch" EXACT [] synonym: "ventral branchial pouch 5 endoderm" RELATED [] [Term] id: UBERON:0003702 ! inguinal canal name: inguinal canal def: "The inguinal canal is a passage in the anterior (toward the front of the body) abdominal wall which in men conveys the spermatic cord + the ilioinguinal nerve and in women the round ligament + the ilioinguinal nerve. The inguinal canal is larger and more prominent in men. [WP,unvetted]." [Wikipedia:Inguinal_canal] xref: FMA:19928 ! Inguinal canal xref: GAID:28 ! inguinal canal xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b4/Gray1227.png/200px-Gray1227.png xref: EMAPA:19171 ! inguinal canal of female reproductive system (also: UBERON:0004353 'female inguinal canal') xref: EMAPA:26913 ! inguinal canal of male reproductive system (also: UBERON:0004354 'male inguinal canal') xref: MESH:A01.047.412 ! inguinal canal is_a: UBERON:0004111 {source="FMA"} ! anatomical conduit relationship: located_in UBERON:0003697 {source="Wikipedia"} ! abdominal wall xref: SCTID:243966008 ! Entire inguinal canal xref: ncithesaurus:Inguinal_Canal ! inguinal canal synonym: "canalis inguinalis" RELATED LATIN [Wikipedia:Inguinal_canal] xref: http://upload.wikimedia.org/wikipedia/commons/b/b4/Gray1227.png xref: UMLS:C0021445 [Term] id: UBERON:0004353 name: female inguinal canal def: "An inguinal canal that is part of a female organism. Conveys the round ligament + the ilioinguinal nerve.[WP,unvetted]." [Wikipedia:Inguinal_canal#Contents, MP:0008015] comment: AO notes: in MP, this is implicitly part of female reproductive system, but not female genitalia xref: EMAPA:19171 ! inguinal canal of female reproductive system (also: UBERON:0003702 'inguinal canal') intersection_of: UBERON:0003702 ! inguinal canal intersection_of: part_of UBERON:0000474 ! female reproductive system [Term] id: UBERON:0004354 name: male inguinal canal def: "An inguinal canal that is part of a male organism. Conveys the spermatic cord and its coverings + the ilioinguinal nerve.[WP,unvetted]." [Wikipedia:Inguinal_canal#Contents, MP:0008016] comment: AO notes: in MP, this is implicitly part of male reproductive system, but not male genitalia xref: EMAPA:26913 ! inguinal canal of male reproductive system (also: UBERON:0003702 'inguinal canal') intersection_of: UBERON:0003702 ! inguinal canal intersection_of: part_of UBERON:0000079 ! male reproductive system [Term] id: UBERON:0004355 name: podocyte foot process def: "the footlike extension of podocytes that interdigitate with one another to form the walls of the glomerular capillaries" [MP:0008059] comment: TODO - submit to GO is_a: UBERON:0000061 ! anatomical structure relationship: part_of CL:0000653 ! podocyte [Term] id: UBERON:0004361 name: stylohyoid ligament def: "the fibrous cord that connects the tip of the styloid process of the temporal bone to the lesser horn of the hyoid bone" [MP:0009918, Wikipedia:Stylohyoid_ligament] synonym: "stylo-hyoid ligament" EXACT [MA:0002957] synonym: "ligamentum stylohyoideus" EXACT [Wikipedia:Stylohyoid_ligament] synonym: "ligamentum stylohyoideum" EXACT [Wikipedia:Stylohyoid_ligament] xref: FMA:72308 ! stylohyoid ligament xref: MA:0002957 ! stylohyoid ligament is_a: UBERON:0008846 {source="FMA"} ! skeletal ligament relationship: develops_from UBERON:0004368 {source="MP-implied-by-def"} ! Reichert's cartilage relationship: connects UBERON:0003960 {source="Wikipedia"} ! styloid process relationship: connects UBERON:0003998 {source="Wikipedia"} ! hyoid bone lesser horn xref: SCTID:66275001 ! Entire stylohyoid ligament [Term] id: UBERON:0004365 name: vitelline blood vessel def: "blood vesself of the yolk sac." [MP:0001719] intersection_of: UBERON:0001981 ! blood vessel intersection_of: overlaps UBERON:0001040 ! yolk sac relationship: part_of UBERON:0004374 ! vitelline vasculature [Term] id: UBERON:0004374 name: vitelline vasculature def: "vasculature of the yolk sac." [MP:0001719] synonym: "omphalomesenteric system" RELATED [UBERON:cjm] synonym: "vitelline system" RELATED [UBERON:cjm] synonym: "vitelline bloos vessel system" RELATED [UBERON:cjm] intersection_of: UBERON:0002049 ! vasculature intersection_of: overlaps UBERON:0001040 ! yolk sac [Term] id: UBERON:0004367 name: Descemet's membrane def: "transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. The strong, resistant, thin, noncellular fourth layer of the cornea, located between the endothelium (from which it is secreted) and the stroma. (Cline et al., Dictionary of Visual Science, 4th ed)." [MP:0004285] subset: vertebrate_core synonym: "Descemet membrane" EXACT [] synonym: "Descemet's posterior elastic lamina" EXACT [FMA:58309] synonym: "posterior limiting lamina of cornea " EXACT [FMA:58309] synonym: "lamina limitans posterior" EXACT [FMA:58309] synonym: "posterior limiting lamina " EXACT [MA:0001246] synonym: "posterior limiting lamina" EXACT [MA:0001246] synonym: "posterior limiting lamina of cornea" EXACT [FMA:58309] xref: GAID:894 ! descemet's membrane xref: FMA:58309 ! posterior limiting lamina of cornea xref: MA:0001246 ! posterior limiting lamina xref: ncithesaurus:Descemet_s_Membrane ! Descemet's Membrane xref: ZFA:0001686 ! Descemet's membrane xref: EMAPA:18804 ! Descemet's membrane xref: MESH:A09.371.060.217.271 ! descemet's membrane is_a: UBERON:0005769 ! basement membrane relationship: adjacent_to UBERON:0001985 ! corneal endothelium relationship: adjacent_to UBERON:0001777 ! substantia propria of cornea relationship: part_of UBERON:0000964 ! cornea xref: SCTID:281076002 ! Entire Descemet's membrane xref: TAO:0002157 ! Descemet's membrane property_value: external_definition "Portion of tissue that is the innermost layer of the cornea and consists of a monolayer of ploygonal cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002157", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-061010-3"} xref: UMLS:C0011665 [Term] id: UBERON:0010354 ! Reichert's cartilage pre-cartilage condensation name: Reichert's cartilage pre-cartilage condensation synonym: "hyoid cartilage pre-cartilage condensation" EXACT [EMAPA:17351] synonym: "future Reichert's cartilage" EXACT [] xref: EMAPA:17351 ! hyoid cartilage pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0010254 {source="EHDAA2", source="doi:10.1111/j.1469-7580.2005.00441.x"} ! 2nd arch mesenchyme from neural crest [Term] id: UBERON:0004368 name: Reichert's cartilage def: "a continuous cartilaginous formation in mesenchyme of the second pharyngeal arch in the embryo. The longer cranial or styloid segment is continuous with the otic capsule; its inferior end is angulated and is situated very close to the oropharynx. The smaller caudal segment is in contact with the body and greater horn of the hyoid cartilaginous structure" [MP:0004916, doi:10.1111/j.1469-7580.2006.00524.x] comment: AO notes: in EHDAA2 this also develops from 3rd arch Mes from NC. Development notes: Classically defined as: a structure... develop the stapes, the styloid processes, the stylohyoid ligaments, and the lesser cornua of the hyoid bone; its proximal end gives rise to the stylohyoid ligament. Relationship to stapes disputed. synonym: "Reichert cartilage" EXACT [] synonym: "hyaloid cartilage" EXACT [MP:0004916] synonym: "second pharyngeal arch cartilage" EXACT [MP:0004916] synonym: "second branchial arch cartilage" EXACT [] synonym: "hyoid cartilage" EXACT [EHDAA2:0000793] xref: EMAPA:17622 ! hyoid cartilage cartilage condensation xref: EHDAA2:0000793 ! hyoid cartilage is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0003066 ! pharyngeal arch 2 relationship: part_of UBERON:0001557 {source="EHDAA2"} ! upper respiratory tract relationship: develops_from UBERON:0010354 ! Reichert's cartilage pre-cartilage condensation [Term] id: UBERON:0004369 name: Reichert's membrane def: "An nonvascular extraembryonic basement membrane that forms on the inner surface of the trophectoderm during placenta morphogenesis and is secreted by the distal parietal endoderm; required for the maternofetal exchange of nutrients and is important for the postgastrulation development[MP]. a thick multilayered basement membrane between the parietal endoderm cells and the trophoblast cells" [DOI:10.1007/BF00184752, MP:0003954] xref: EMAPA:16057 ! Reichert's membrane is_a: UBERON:0000478 ! extraembryonic structure relationship: surrounded_by UBERON:0000088 ! trophoblast relationship: surrounded_by UBERON:0000925 ! endoderm [Term] id: UBERON:0004370 name: anterior limiting lamina of cornea subset: vertebrate_core synonym: "anterior limiting lamina of cornea" EXACT [FMA:58273] synonym: "Bowman's anterior elastic lamina" EXACT [FMA:58273] synonym: "Bowman's membrane" EXACT [FMA:58273] synonym: "Reichert's membrane" RELATED DUBIOUS [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] synonym: "Bowman's layer" EXACT [FMA:58273] synonym: "lamina limitans anterior (cornea)" EXACT [FMA:58273] synonym: "anterior limiting lamina" EXACT [MA:0001240] xref: FMA:58273 ! anterior limiting lamina of cornea xref: ncithesaurus:Bowman_s_Membrane ! Bowman's Membrane xref: ZFA:0001684 ! Bowman's layer xref: MA:0001240 ! anterior limiting lamina is_a: UBERON:0005769 ! basement membrane relationship: part_of UBERON:0000964 ! cornea xref: SCTID:281075003 ! Entire Bowman's layer xref: TAO:0002155 ! Bowman's layer property_value: external_definition "Acellular anatomical structure that is the zone of collagen fibers adjacent the basement membrane of the corneal epithelium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002155", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-061010-3"} xref: UMLS:C0229127 [Term] id: UBERON:0004375 name: bone of free limb or fin def: "A bone that is part of an appendage [Automatically generated definition]." [OBOL:automatic] synonym: "bone of free segment of appendicular skeleton" EXACT [] synonym: "appendage bone" EXACT [] synonym: "bone of appendage" EXACT [] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0004708 ! limb/fin relationship: part_of UBERON:0011582 ! limb/fin skeleton [Term] id: UBERON:0004376 name: fin bone def: "A bone that is part of a fin [Automatically generated definition]." [OBOL:automatic] synonym: "bone of fin" EXACT [] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0008897 ! fin relationship: part_of UBERON:0012353 ! fin skeleton [Term] id: UBERON:0004382 ! epiphysis of humerus name: epiphysis of humerus def: "An epiphysis that is part of a humerus [Automatically generated definition]." [OBOL:automatic] synonym: "humeral epiphysis" EXACT [OBOL:automatic] xref: FMA:32825 ! Epiphysis of humerus intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0000976 ! humerus xref: SCTID:313054009 ! Epiphysis of humerus [Term] id: UBERON:0004383 name: epiphysis of tibia def: "An epiphysis that is part of a tibia [Automatically generated definition]." [OBOL:automatic] synonym: "tibial epiphysis" EXACT [FMA:33112] xref: FMA:33112 ! Epiphysis of tibia intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0000979 ! part_of tibia xref: SCTID:314626006 ! Tibial epiphysis [Term] id: UBERON:0004384 name: epiphysis of femur def: "An epiphysis that is part of a femur [Automatically generated definition]." [OBOL:automatic] synonym: "femoral epiphysis" EXACT [FMA:32838] xref: FMA:32838 ! Epiphysis of femur intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0000981 ! part_of femur xref: SCTID:314625005 ! Femoral epiphysis [Term] id: UBERON:0004385 name: epiphysis of radius def: "An epiphysis that is part of a radius [Automatically generated definition]." [OBOL:automatic] synonym: "radial epiphysis" EXACT [FMA:33770] xref: FMA:33770 ! Epiphysis of radius intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001423 ! part_of radius xref: SCTID:313055005 ! Epiphysis of radius [Term] id: UBERON:0004386 name: epiphysis of ulna def: "An epiphysis that is part of an ulna [Automatically generated definition]." [OBOL:automatic] synonym: "ulnar epiphysis" EXACT [FMA:33748] xref: FMA:33748 ! Epiphysis of ulna intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001424 ! part_of ulna xref: SCTID:313056006 ! Epiphysis of ulna [Term] id: UBERON:0004387 name: epiphysis of phalanx of manus def: "An epiphysis that is part of a phalanx of a manus [Automatically generated definition]." [OBOL:automatic] synonym: "epiphysis of phalanx of finger" EXACT [] xref: FMA:240707 ! epiphysis of phalanx of finger intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001436 ! phalanx of manus xref: SCTID:314620000 ! Epiphysis of phalanx of finger [Term] id: UBERON:0011973 name: epiphysis of phalanx of pes def: "An epiphysis that is part of a phalanx of a pes [Automatically generated definition]." [OBOL:automatic] synonym: "epiphysis of phalanx of toe" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0002387 ! pes xref: SCTID:314621001 ! Epiphysis of phalanx of toe [Term] id: UBERON:0004388 name: epiphysis of fibula def: "An epiphysis that is part of a fibula [Automatically generated definition]." [OBOL:automatic] synonym: "fibula epiphysis" EXACT [FMA:33726] xref: FMA:33726 ! Epiphysis of fibula intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001446 ! part_of fibula [Term] id: UBERON:0004389 name: epiphysis of metatarsal bone def: "An epiphysis that is part of a metatarsal bone [Automatically generated definition]." [OBOL:automatic] synonym: "metatarsal bone epiphysis" EXACT [FMA:33814] synonym: "metatarsal epiphysis" EXACT [] synonym: "epiphysis of metatarsal" EXACT [] xref: FMA:33814 ! Epiphysis of metatarsal bone xref: SCTID:313057002 ! Epiphysis of metacarpal intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001448 ! part_of metatarsal bone [Term] id: UBERON:0004390 name: epiphysis of metacarpal bone def: "An epiphysis that is part of a metacarpal bone [Automatically generated definition]." [OBOL:automatic] synonym: "metacarpal bone epiphysis" EXACT [FMA:33792] synonym: "metacarpal epiphysis" EXACT [] synonym: "epiphysis of metacarpal" EXACT [] xref: FMA:33792 ! Epiphysis of metacarpal bone xref: SCTID:314907001 ! Epiphysis of metatarsal intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0002374 ! part_of metacarpal bone [Term] id: UBERON:0004391 name: epiphysis of first metacarpal bone def: "An epiphysis that is part of a metacarpal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "first metacarpal bone epiphysis" EXACT [FMA:33793] synonym: "metacarpal 1 epiphysis" EXACT [] xref: FMA:33793 ! Epiphysis of first metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003645 ! part_of metacarpal bone of digit 1 [Term] id: UBERON:0004392 name: epiphysis of second metacarpal bone def: "An epiphysis that is part of a metacarpal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "second metacarpal bone epiphysis" EXACT [FMA:33794] synonym: "metacarpal 2 epiphysis" EXACT [] xref: FMA:33794 ! Epiphysis of second metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003646 ! part_of metacarpal bone of digit 2 [Term] id: UBERON:0004393 name: epiphysis of third metacarpal bone def: "An epiphysis that is part of a metacarpal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "third metacarpal bone epiphysis" EXACT [FMA:86328] synonym: "metacarpal 3 epiphysis" EXACT [] xref: FMA:86328 ! Epiphysis of third metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003647 ! part_of metacarpal bone of digit 3 [Term] id: UBERON:0004394 name: epiphysis of fourth metacarpal bone def: "An epiphysis that is part of a metacarpal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "fourth metacarpal bone epiphysis" EXACT [FMA:86329] synonym: "metacarpal 4 epiphysis" EXACT [] xref: FMA:86329 ! Epiphysis of fourth metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003648 ! part_of metacarpal bone of digit 4 [Term] id: UBERON:0011104 name: epiphysis of fifth metacarpal bone synonym: "fifth metacarpal bone epiphysis" EXACT [FMA:86330] synonym: "metacarpal 5 epiphysis" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003649 ! metacarpal bone of digit 5 xref: FMA:86330 ! epiphysis of fifth metacarpal bone def: "An epiphysis that is part of a metacarpal bone of digit 5." [OBOL:automatic] [Term] id: UBERON:0004395 name: epiphysis of first metatarsal bone def: "An epiphysis that is part of a metatarsal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "first metatarsal bone epiphysis" EXACT [FMA:33815] synonym: "metatarsal 1 epiphysis" EXACT [] xref: FMA:33815 ! Epiphysis of first metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003650 ! part_of metatarsal bone of digit 1 [Term] id: UBERON:0004396 name: epiphysis of second metatarsal bone def: "An epiphysis that is part of a metatarsal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "second metatarsal bone epiphysis" EXACT [FMA:33816] synonym: "metatarsal 2 epiphysis" EXACT [] xref: FMA:33816 ! Epiphysis of second metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003651 ! part_of metatarsal bone of digit 2 [Term] id: UBERON:0004397 name: epiphysis of third metatarsal bone def: "An epiphysis that is part of a metatarsal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "third metatarsal bone epiphysis" EXACT [FMA:86313] synonym: "metatarsal 3 epiphysis" EXACT [] xref: FMA:86313 ! Epiphysis of third metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003652 ! part_of metatarsal bone of digit 3 [Term] id: UBERON:0004398 name: epiphysis of fourth metatarsal bone def: "An epiphysis that is part of a metatarsal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "fourth metatarsal bone epiphysis" EXACT [FMA:86314] synonym: "metatarsal 4 epiphysis" EXACT [] xref: FMA:86314 ! Epiphysis of fourth metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003653 ! part_of metatarsal bone of digit 4 [Term] id: UBERON:0004399 name: epiphysis of fifth metatarsal bone def: "An epiphysis that is part of a metatarsal bone of digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "fifth metatarsal bone epiphysis" EXACT [FMA:86315] synonym: "metatarsal 5 epiphysis" EXACT [] xref: FMA:86315 ! Epiphysis of fifth metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003654 ! part_of metatarsal bone of digit 5 [Term] id: UBERON:0004400 name: bone tissue of epiphysis def: "A portion of bone tissue that is part of a epiphysis [Automatically generated definition]." [OBOL:automatic] xref: FMA:241364 ! Bone tissue of epiphysis intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0001437 ! part_of epiphysis [Term] id: UBERON:0004401 name: bone tissue of distal epiphysis def: "A portion of bone tissue that is part of a distal epiphysis [Automatically generated definition]." [OBOL:automatic] xref: FMA:241374 ! Bone tissue of distal epiphysis intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0004379 ! part_of distal epiphysis [Term] id: UBERON:0004402 name: bone tissue of proximal epiphysis def: "A portion of bone tissue that is part of a proximal epiphysis [Automatically generated definition]." [OBOL:automatic] xref: FMA:241372 ! Bone tissue of proximal epiphysis intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0004380 ! part_of proximal epiaphysis [Term] id: UBERON:0004403 name: periosteum of epiphysis def: "A periosteum that is part of a epiphysis [Automatically generated definition]." [OBOL:automatic] synonym: "epiphysis periosteum" EXACT [FMA:32687] xref: FMA:32687 ! Periosteum of epiphysis intersection_of: UBERON:0002515 ! periosteum intersection_of: part_of UBERON:0001437 ! part_of epiphysis [Term] id: UBERON:0004404 name: distal epiphysis of humerus def: "A distal epiphysis that is part of a humerus [Automatically generated definition]." [OBOL:automatic] synonym: "distal end of humerus" EXACT [FMA:32826] synonym: "lower end of humerus" EXACT [FMA:32826] xref: FMA:32826 ! Distal epiphysis of humerus intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0000976 ! humerus xref: SCTID:310655007 ! Entire distal end of humerus [Term] id: UBERON:0004405 name: distal epiphysis of tibia def: "A distal epiphysis that is part of a tibia [Automatically generated definition]." [OBOL:automatic] synonym: "distal end of tibia" EXACT [FMA:33116] synonym: "lower end of tibia" EXACT [FMA:33116] xref: FMA:33116 ! Distal epiphysis of tibia intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0000979 ! tibia xref: SCTID:302527001 ! Entire lower end of tibia [Term] id: UBERON:0004406 name: distal epiphysis of femur def: "A distal epiphysis that is part of a femur [Automatically generated definition]." [OBOL:automatic] synonym: "distal femoral epiphysis" EXACT [OBOL:automatic, UBERON:cjm] synonym: "distal head of femur" RELATED [AAO:0000893] xref: FMA:32844 ! Distal epiphysis of femur intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0000981 ! femur xref: SCTID:280016000 ! Entire distal epiphysis of femur xref: AAO:0000893 ! distal head property_value: external_definition "Head of the femur that articulates with the tibia and fibula.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000893", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0004407 name: distal epiphysis of radius def: "A distal epiphysis that is part of a radius [Automatically generated definition]." [OBOL:automatic] synonym: "distal end of radius" EXACT [FMA:33776] synonym: "lower end of radius" EXACT [FMA:33776] xref: FMA:33776 ! Distal epiphysis of radius intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001423 ! radius xref: SCTID:280013008 ! Entire distal epiphysis of radius [Term] id: UBERON:0004408 name: distal epiphysis of ulna def: "A distal epiphysis that is part of a ulna [Automatically generated definition]." [OBOL:automatic] synonym: "distal end of ulna" EXACT [FMA:33754] synonym: "lower end of ulna" EXACT [FMA:33754] xref: FMA:33754 ! Distal epiphysis of ulna intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001424 ! ulna xref: SCTID:302521000 ! Entire distal end of ulna [Term] id: UBERON:0004409 name: distal epiphysis of phalanx of manus def: "A distal epiphysis that is part of a phalanx of manus [Automatically generated definition]." [OBOL:automatic] synonym: "distal epiphysis of phalanx of finger" EXACT [] xref: FMA:226577 ! Distal epiphysis of phalanx of finger intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001436 ! part_of phalanx of manus [Term] id: UBERON:0011974 name: epiphysis of proximal phalanx of pes synonym: "epiphysis of proximal phalanx of toe" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003868 ! proximal phalanx of pes xref: SCTID:280047006 ! Epiphysis of proximal phalanx of toe def: "An epiphysis that is part of a proximal phalanx of pes." [OBOL:automatic] [Term] id: UBERON:0011975 name: epiphysis of middle phalanx of pes synonym: "epiphysis of middle phalanx of toe" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003866 ! middle phalanx of toe xref: SCTID:280048001 ! Epiphysis of middle phalanx of toe def: "An epiphysis that is part of a middle phalanx of pes." [OBOL:automatic] [Term] id: UBERON:0011976 name: epiphysis of distal phalanx of pes synonym: "epiphysis of distal phalanx of toe" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003867 ! distal phalanx of pes xref: SCTID:280049009 ! Epiphysis of distal phalanx of toe def: "An epiphysis that is part of a distal phalanx of pes." [OBOL:automatic] [Term] id: UBERON:0011977 name: epiphysis of proximal phalanx of manus synonym: "epiphysis of proximal phalanx of finger" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0002234 ! proximal phalanx of manus xref: SCTID:280044004 ! Epiphysis of proximal phalanx of finger def: "An epiphysis that is part of a proximal phalanx of manus." [OBOL:automatic] [Term] id: UBERON:0011978 name: epiphysis of middle phalanx of manus synonym: "epiphysis of middle phalanx of finger" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003864 ! middle phalanx of manus xref: SCTID:280045003 ! Epiphysis of middle phalanx of finger def: "An epiphysis that is part of a middle phalanx of manus." [OBOL:automatic] [Term] id: UBERON:0011979 name: epiphysis of distal phalanx of manus synonym: "epiphysis of distal phalanx of finger" EXACT [] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003865 ! distal phalanx of manus xref: SCTID:280046002 ! Epiphysis of distal phalanx of finger def: "An epiphysis that is part of a distal phalanx of manus." [OBOL:automatic] [Term] id: UBERON:0004410 name: distal epiphysis of fibula def: "A distal epiphysis that is part of a fibula [Automatically generated definition]." [OBOL:automatic] synonym: "distal end of fibula" EXACT [FMA:33732] synonym: "lower end of fibula" EXACT [FMA:33732] xref: FMA:33732 ! Distal epiphysis of fibula intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001446 ! fibula xref: SCTID:129111008 ! Epiphysis of distal fibula xref: SCTID:280018004 ! Distal fibular epiphysis [Term] id: UBERON:0012291 name: lateral malleolus of fibula synonym: "distal extremity of fibula" RELATED [Wikipedia:Malleolus#Lateral_malleolus] synonym: "external malleolus of fibula" RELATED [Wikipedia:Malleolus#Lateral_malleolus] synonym: "lateral malleolus" BROAD [FMA:35502] synonym: "fibular malleolus" RELATED [] synonym: "malleolar bone" NARROW SENSU [] synonym: "malleolar bone of ankle" NARROW SENSU [] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004410 ! distal epiphysis of fibula xref: FMA:35502 ! lateral malleolus xref: SCTID:361795009 ! Entire lateral malleolus of fibula property_value: taxon_notes "In bovids, the distal end of the fibula is present only as the lateral malleolus, a separate bone that articulates with the lateral side of the distal tibia." xsd:string {scope="NCBITaxon:9895", source="UBERON:skansa", seeAlso="UBERON:0004410"} [Term] id: UBERON:0004411 name: proximal epiphysis of humerus def: "The upper extremity of the humerus (proximal humerus) consists of a large rounded head joined to the body by a constricted portion called the neck, and two eminences, the greater and lesser tubercles." [Wikipedia:Upper_extremity_of_humerus] synonym: "head of the humerus" RELATED [Wikipedia:Upper_extremity_of_humerus] synonym: "humeral head" RELATED [Wikipedia:Upper_extremity_of_humerus] synonym: "proximal humerus" RELATED [Wikipedia:Upper_extremity_of_humerus] synonym: "upper extremity of humerus" RELATED [Wikipedia:Upper_extremity_of_humerus] synonym: "proximal humeral epiphysis" EXACT [OBOL:automatic, UBERON:cjm] synonym: "proximal end of humerus" EXACT [FMA:23362] synonym: "upper end of humerus" EXACT [FMA:23362] xref: FMA:23362 ! Proximal epiphysis of humerus intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0000976 ! humerus xref: SCTID:280028008 ! Proximal humeral epiphysis xref: http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray207.png [Term] id: UBERON:0004412 name: proximal epiphysis of femur def: "A proximal epiphysis that is part of a femur [Automatically generated definition]." [OBOL:automatic] synonym: "proximal femoral epiphysis" EXACT [OBOL:automatic, UBERON:cjm] xref: FMA:32841 ! Proximal epiphysis of femur intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0000981 ! femur xref: SCTID:244702009 ! Entire proximal epiphysis of femur [Term] id: UBERON:0004413 name: proximal epiphysis of radius def: "A proximal epiphysis that is part of a radius [Automatically generated definition]." [OBOL:automatic] synonym: "proximal radial epiphysis" EXACT [OBOL:automatic, UBERON:cjm] synonym: "proximal end of radius" EXACT [FMA:39780] synonym: "upper end of radius" EXACT [FMA:39780] xref: FMA:39780 ! Proximal epiphysis of radius intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0001423 ! radius xref: SCTID:280029000 ! Entire proximal epiphysis of radius [Term] id: UBERON:0004414 name: proximal epiphysis of phalanx of manus def: "A proximal epiphysis that is part of a phalanx of manus [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of finger" EXACT [FMA:226482] synonym: "base of phalanx of finger" EXACT [FMA:226482] synonym: "proximal epiphysis of phalanx of finger" EXACT [] xref: FMA:226482 ! Proximal epiphysis of phalanx of finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0001436 ! part_of phalanx of manus synonym: "basis phalangis manus" EXACT LATIN [FMA:TA, FMA:226482] xref: SCTID:272704004 ! Base of phalanx of finger [Term] id: UBERON:0013121 name: proximal epiphysis of phalanx of pes synonym: "basal epiphysis of phalanx of foot" EXACT [FMA:32888] synonym: "base of phalanx of foot" EXACT [FMA:32888] synonym: "basis phalangis (pedis)" EXACT [FMA:32888] synonym: "basis phalangis pedis" EXACT [FMA:TA] intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0001449 ! phalanx of pes xref: FMA:32888 ! proximal epiphysis of phalanx of toe synonym: "proximal epiphysis of phalanx of toe" EXACT [FMA:32888] [Term] id: UBERON:0004415 name: proximal epiphysis of metatarsal bone def: "A proximal epiphysis that is part of a metatarsal bone [Automatically generated definition]." [OBOL:automatic] synonym: "base of metatarsal bone" EXACT [FMA:33817] synonym: "proximal end of metatarsal bone" EXACT [FMA:33817] synonym: "upper end of metatarsal bone" EXACT [FMA:33817] xref: FMA:33817 ! Proximal epiphysis of metatarsal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0001448 ! metatarsal bone synonym: "basis ossis metatarsi" EXACT LATIN [FMA:TA, FMA:33817] xref: SCTID:119545008 ! Structure of base of metatarsal bone [Term] id: UBERON:0004416 name: proximal epiphysis of metacarpal bone def: "A proximal epiphysis that is part of a metacarpal bone [Automatically generated definition]." [OBOL:automatic] synonym: "base of metacarpal bone" EXACT [FMA:33795] synonym: "metacarpal bone base" EXACT [FMA:33795] synonym: "proximal end of metacarpal bone" EXACT [FMA:33795] synonym: "upper end of metacarpal bone" EXACT [FMA:33795] xref: FMA:33795 ! Proximal epiphysis of metacarpal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0002374 ! metacarpal bone synonym: "basis ossis metacarpi" EXACT LATIN [FMA:TA, FMA:33795] xref: SCTID:272695001 ! Entire base of metacarpal bone [Term] id: UBERON:0004417 name: proximal epiphysis of phalanx of manual digit 1 def: "A proximal epiphysis that is part of a manual digit 1 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of thumb" EXACT [FMA:37489] synonym: "base of phalanx of first digit of hand" EXACT [FMA:37489] synonym: "base of phalanx of thumb" EXACT [FMA:37489] synonym: "proximal epiphysis of phalanx of manual digit 1" EXACT [] xref: FMA:37489 ! Proximal epiphysis of phalanx of thumb intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003620 ! part_of manual digit 1 phalanx xref: SCTID:272700008 ! Entire base of phalanx of thumb synonym: "proximal epiphysis of phalanx of thumb" NARROW SENSU [NCBITaxon:9606, FMA:37489] [Term] id: UBERON:0004418 name: proximal epiphysis of phalanx of manual digit 2 def: "A proximal epiphysis that is part of a manual digit 2 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of index finger" EXACT [FMA:37498] synonym: "base of phalanx of index finger" EXACT [FMA:37498] synonym: "base of phalanx of second digit of hand" EXACT [FMA:37498] synonym: "base of phalanx of second finger" EXACT [FMA:37498] synonym: "proximal epiphysis of phalanx of manual digit 2" EXACT [] xref: FMA:37498 ! Proximal epiphysis of phalanx of index finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003636 ! part_of manual digit 2 phalanx xref: SCTID:368307004 ! Entire base of phalanx of index finger synonym: "proximal epiphysis of phalanx of index finger" NARROW SENSU [NCBITaxon:9606, FMA:37498] [Term] id: UBERON:0004419 name: proximal epiphysis of phalanx of manual digit 3 def: "A proximal epiphysis that is part of a manual digit 3 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of middle finger" EXACT [FMA:37510] synonym: "base of phalanx of middle finger" EXACT [FMA:37510] synonym: "base of phalanx of third digit of hand" EXACT [FMA:37510] synonym: "base of phalanx of third finger" EXACT [FMA:37510] synonym: "proximal epiphysis of phalanx of manual digit 3" EXACT [] xref: FMA:37510 ! Proximal epiphysis of phalanx of middle finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003637 ! part_of manual digit 3 phalanx xref: SCTID:181997000 ! Base of middle phalanx of finger synonym: "proximal epiphysis of phalanx of middle finger" NARROW SENSU [NCBITaxon:9606, FMA:37510] [Term] id: UBERON:0004420 name: proximal epiphysis of phalanx of manual digit 4 def: "A proximal epiphysis that is part of a manual digit 4 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of ring finger" EXACT [FMA:37522] synonym: "base of phalanx of fourth digit of hand" EXACT [FMA:37522] synonym: "base of phalanx of fourth finger" EXACT [FMA:37522] synonym: "base of phalanx of ring finger" EXACT [FMA:37522] synonym: "proximal epiphysis of phalanx of manual digit 4" EXACT [] xref: FMA:37522 ! Proximal epiphysis of phalanx of ring finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003638 ! part_of manual digit 4 phalanx xref: SCTID:368337008 ! Entire base of phalanx of ring finger synonym: "proximal epiphysis of phalanx of ring finger" NARROW SENSU [NCBITaxon:9606, FMA:37522] [Term] id: UBERON:0004421 name: proximal epiphysis of phalanx of manual digit 5 def: "A proximal epiphysis that is part of a manual digit 5 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of fifth finger" EXACT [FMA:37534] synonym: "basal epiphysis of phalanx of little finger" EXACT [FMA:37534] synonym: "base of phalanx of fifth digit of hand" EXACT [FMA:37534] synonym: "base of phalanx of fifth finger" EXACT [FMA:37534] synonym: "base of phalanx of little finger" EXACT [FMA:37534] synonym: "proximal epiphysis of phalanx of manual digit 5" EXACT [] xref: FMA:37534 ! Proximal epiphysis of phalanx of little finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003639 ! part_of manual digit 5 phalanx xref: SCTID:368351008 ! Entire base of phalanx of little finger synonym: "proximal epiphysis of phalanx of little finger" NARROW SENSU [NCBITaxon:9606, FMA:37534] [Term] id: UBERON:0004422 name: proximal epiphysis of first metacarpal bone def: "A proximal epiphysis that is part of a metacarpal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "base of first metacarpal bone" EXACT [FMA:42788] synonym: "first metacarpal bone base" EXACT [FMA:42788] synonym: "proximal epiphysis of metacarpal 1" EXACT [] xref: FMA:42788 ! Proximal epiphysis of first metacarpal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003645 ! metacarpal bone of digit 1 xref: SCTID:181978000 ! Entire base of first metacarpal bone [Term] id: UBERON:0004423 name: proximal epiphysis of second metacarpal bone def: "A proximal epiphysis that is part of a metacarpal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "base of second metacarpal bone" EXACT [FMA:42791] synonym: "proximal end of second metacarpal bone" EXACT [FMA:42791] synonym: "second metacarpal bone base" EXACT [FMA:42791] synonym: "proximal epiphysis of metacarpal 2" EXACT [] xref: FMA:42791 ! Proximal epiphysis of second metacarpal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003646 ! metacarpal bone of digit 2 xref: SCTID:263461004 ! Entire base of second metacarpal bone [Term] id: UBERON:0004424 name: proximal epiphysis of third metacarpal bone def: "A proximal epiphysis that is part of a metacarpal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "base of third metacarpal bone" EXACT [FMA:42794] synonym: "proximal end of third metacarpal bone" EXACT [FMA:42794] synonym: "third metacarpal bone base" EXACT [FMA:42794] synonym: "proximal epiphysis of metacarpal 3" EXACT [] xref: FMA:42794 ! Proximal epiphysis of third metacarpal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003647 ! metacarpal bone of digit 3 xref: SCTID:263465008 ! Entire base of third metacarpal bone [Term] id: UBERON:0004425 name: proximal epiphysis of fourth metacarpal bone def: "A proximal epiphysis that is part of a metacarpal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fourth metacarpal bone" EXACT [FMA:42797] synonym: "fourth metacarpal bone base" EXACT [FMA:42797] synonym: "proximal end of fourth metacarpal bone" EXACT [FMA:42797] synonym: "proximal epiphysis of metacarpal 4" EXACT [] xref: FMA:42797 ! Proximal epiphysis of fourth metacarpal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003648 ! metacarpal bone of digit 4 xref: SCTID:263469002 ! Entire base of fourth metacarpal bone [Term] id: UBERON:0004426 name: proximal epiphysis of fifth metacarpal bone def: "A proximal epiphysis that is part of a metacarpal bone of digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fifth metacarpal bone" EXACT [FMA:42800] synonym: "fifth metacarpal bone base" EXACT [FMA:42800] synonym: "proximal end of fifth metacarpal bone" EXACT [FMA:42800] synonym: "proximal epiphysis of metacarpal 5" EXACT [] xref: FMA:42800 ! Proximal epiphysis of fifth metacarpal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003649 ! metacarpal bone of digit 5 xref: SCTID:263473004 ! Entire base of fifth metacarpal bone [Term] id: UBERON:0004427 name: proximal epiphysis of first metatarsal bone def: "A proximal epiphysis that is part of a metatarsal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "base of first metatarsal bone" EXACT [FMA:42963] synonym: "proximal end of first metatarsal bone" EXACT [FMA:42963] synonym: "proximal epiphysis of metatarsal 1" EXACT [] xref: FMA:42963 ! Proximal epiphysis of first metatarsal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003650 ! metatarsal bone of digit 1 xref: SCTID:182124002 ! Entire base of first metatarsal bone [Term] id: UBERON:0004428 name: proximal epiphysis of second metatarsal bone def: "A proximal epiphysis that is part of a metatarsal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "base of second metatarsal bone" EXACT [FMA:42964] synonym: "proximal end of second metatarsal bone" EXACT [FMA:42964] synonym: "proximal epiphysis of metatarsal 2" EXACT [] xref: FMA:42964 ! Proximal epiphysis of second metatarsal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003651 ! metatarsal bone of digit 2 xref: SCTID:182130002 ! Entire base of second metatarsal bone [Term] id: UBERON:0004429 name: proximal epiphysis of third metatarsal bone def: "A proximal epiphysis that is part of a metatarsal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "base of third metatarsal bone" EXACT [FMA:42965] synonym: "proximal end of third metatarsal bone" EXACT [FMA:42965] synonym: "proximal epiphysis of metatarsal 3" EXACT [] xref: FMA:42965 ! Proximal epiphysis of third metatarsal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003652 ! metatarsal bone of digit 3 xref: SCTID:182135007 ! Entire base of third metatarsal bone [Term] id: UBERON:0004430 name: proximal epiphysis of fourth metatarsal bone def: "A proximal epiphysis that is part of a metatarsal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fourth metatarsal bone" EXACT [FMA:42966] synonym: "proximal end of fourth metatarsal bone" EXACT [FMA:42966] synonym: "proximal epiphysis of metatarsal 4" EXACT [] xref: FMA:42966 ! Proximal epiphysis of fourth metatarsal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003653 ! metatarsal bone of digit 4 xref: SCTID:182140004 ! Entire base of fourth metatarsal bone [Term] id: UBERON:0004431 name: proximal epiphysis of fifth metatarsal bone def: "A proximal epiphysis that is part of a metatarsal bone of digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fifth metatarsal bone" EXACT [FMA:42967] synonym: "proximal end of fifth metatarsal bone" EXACT [FMA:42967] synonym: "proximal epiphysis of metatarsal 5" EXACT [] xref: FMA:42967 ! Proximal epiphysis of fifth metatarsal bone intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003654 ! metatarsal bone of digit 5 xref: SCTID:182145009 ! Entire base of fifth metatarsal bone [Term] id: UBERON:0004432 name: proximal epiphysis of distal phalanx of manual digit 2 def: "A proximal epiphysis that is part of a distal phalanx of manual digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of distal phalanx of index finger" EXACT [FMA:37505] synonym: "base of distal phalanx of index finger" EXACT [FMA:37505] synonym: "base of distal phalanx of second digit of hand" EXACT [FMA:37505] synonym: "base of distal phalanx of second finger" EXACT [FMA:37505] xref: FMA:37505 ! Proximal epiphysis of distal phalanx of index finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004311 ! part_of distal phalanx of manual digit 2 xref: SCTID:263445001 ! Base of distal phalanx of index finger synonym: "proximal epiphysis of distal phalanx of index finger" NARROW SENSU [NCBITaxon:9606, FMA:37505] [Term] id: UBERON:0004433 name: proximal epiphysis of distal phalanx of manual digit 3 def: "A proximal epiphysis that is part of a distal phalanx of manual digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "base of distal phalanx of middle finger" EXACT [FMA:37517] synonym: "base of distal phalanx of third digit of hand" EXACT [FMA:37517] synonym: "base of distal phalanx of third finger" EXACT [FMA:37517] xref: FMA:37517 ! Proximal epiphysis of distal phalanx of middle finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004312 ! part_of distal phalanx of manual digit 3 xref: SCTID:263446000 ! Base of distal phalanx of middle finger synonym: "proximal epiphysis of distal phalanx of middle finger" NARROW SENSU [NCBITaxon:9606, FMA:37517] [Term] id: UBERON:0004434 name: proximal epiphysis of distal phalanx of manual digit 4 def: "A proximal epiphysis that is part of a distal phalanx of manual digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of distal phalanx of fourth finger" EXACT [FMA:37529] synonym: "basal epiphysis of distal phalanx of ring finger" EXACT [FMA:37529] synonym: "base of distal phalanx of fourth digit of hand" EXACT [FMA:37529] synonym: "base of distal phalanx of fourth finger" EXACT [FMA:37529] synonym: "base of distal phalanx of ring finger" EXACT [FMA:37529] xref: FMA:37529 ! Proximal epiphysis of distal phalanx of ring finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004313 ! part_of distal phalanx of manual digit 4 xref: SCTID:263447009 ! Base of distal phalanx of ring finger synonym: "proximal epiphysis of distal phalanx of ring finger" NARROW SENSU [NCBITaxon:9606, FMA:37529] [Term] id: UBERON:0004435 name: proximal epiphysis of distal phalanx of manual digit 5 def: "A proximal epiphysis that is part of a distal phalanx of manual digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of distal phalanx of fifth finger" EXACT [FMA:37541] synonym: "basal epiphysis of distal phalanx of little finger" EXACT [FMA:37541] synonym: "base of distal phalanx of fifth digit of hand" EXACT [FMA:37541] synonym: "base of distal phalanx of fifth finger" EXACT [FMA:37541] synonym: "base of distal phalanx of little finger" EXACT [FMA:37541] xref: FMA:37541 ! Proximal epiphysis of distal phalanx of little finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004314 ! part_of distal phalanx of manual digit 5 xref: SCTID:263448004 ! Base of distal phalanx of little finger synonym: "proximal epiphysis of distal phalanx of little finger" NARROW SENSU [NCBITaxon:9606, FMA:37541] [Term] id: UBERON:0004436 name: proximal epiphysis of middle phalanx of manual digit 2 def: "A proximal epiphysis that is part of a middle phalanx of manual digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of index finger" EXACT [FMA:37502] synonym: "base of middle phalanx of index finger" EXACT [FMA:37502] synonym: "base of middle phalanx of second digit of hand" EXACT [FMA:37502] synonym: "base of middle phalanx of second finger" EXACT [FMA:37502] xref: FMA:37502 ! Proximal epiphysis of middle phalanx of index finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004320 ! part_of middle phalanx of manual digit 2 xref: SCTID:263428006 ! Base of middle phalanx of index finger synonym: "proximal epiphysis of middle phalanx of index finger" NARROW SENSU [NCBITaxon:9606, FMA:37502] [Term] id: UBERON:0004437 name: proximal epiphysis of middle phalanx of manual digit 3 def: "A proximal epiphysis that is part of a middle phalanx of manual digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of middle finger" EXACT [FMA:37514] synonym: "base of middle phalanx of middle finger" EXACT [FMA:37514] synonym: "base of middle phalanx of third digit of hand" EXACT [FMA:37514] synonym: "base of middle phalanx of third finger" EXACT [FMA:37514] xref: FMA:37514 ! Proximal epiphysis of middle phalanx of middle finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004321 ! part_of middle phalanx of manual digit 3 xref: SCTID:263429003 ! Base of middle phalanx of middle finger synonym: "proximal epiphysis of middle phalanx of middle finger" NARROW SENSU [NCBITaxon:9606, FMA:37514] [Term] id: UBERON:0004438 name: proximal epiphysis of middle phalanx of manual digit 4 def: "A proximal epiphysis that is part of a middle phalanx of manual digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of fourth finger" EXACT [FMA:37526] synonym: "basal epiphysis of middle phalanx of ring finger" EXACT [FMA:37526] synonym: "base of middle phalanx of fourth digit of hand" EXACT [FMA:37526] synonym: "base of middle phalanx of fourth finger" EXACT [FMA:37526] synonym: "base of middle phalanx of ring finger" EXACT [FMA:37526] xref: FMA:37526 ! Proximal epiphysis of middle phalanx of ring finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004322 ! part_of middle phalanx of manual digit 4 xref: SCTID:263430008 ! Base of middle phalanx of ring finger synonym: "proximal epiphysis of middle phalanx of ring finger" NARROW SENSU [NCBITaxon:9606, FMA:37526] [Term] id: UBERON:0004439 name: proximal epiphysis of middle phalanx of manual digit 5 def: "A proximal epiphysis that is part of a middle phalanx of manual digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of fifth finger" EXACT [FMA:37538] synonym: "basal epiphysis of middle phalanx of little finger" EXACT [FMA:37538] synonym: "base of middle phalanx of fifth digit of hand" EXACT [FMA:37538] synonym: "base of middle phalanx of fifth finger" EXACT [FMA:37538] synonym: "base of middle phalanx of little finger" EXACT [FMA:37538] xref: FMA:37538 ! Proximal epiphysis of middle phalanx of little finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004323 ! part_of middle phalanx of manual digit 5 xref: SCTID:263431007 ! Base of middle phalanx of little finger synonym: "proximal epiphysis of middle phalanx of little finger" NARROW SENSU [NCBITaxon:9606, FMA:37538] [Term] id: UBERON:0004440 name: proximal epiphysis of proximal phalanx of manual digit 2 def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "base of proximal phalanx of index finger" EXACT [FMA:37499] synonym: "base of proximal phalanx of second digit of hand" EXACT [FMA:37499] synonym: "base of proximal phalanx of second finger" EXACT [FMA:37499] xref: FMA:37499 ! Proximal epiphysis of proximal phalanx of index finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004328 ! part_of proximal phalanx of manual digit 2 xref: SCTID:263412001 ! Base of proximal phalanx of index finger synonym: "proximal epiphysis of proximal phalanx of index finger" NARROW SENSU [NCBITaxon:9606, FMA:37499] [Term] id: UBERON:0004441 name: proximal epiphysis of proximal phalanx of manual digit 3 def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of middle finger" EXACT [FMA:37511] synonym: "base of proximal phalanx of middle finger" EXACT [FMA:37511] synonym: "base of proximal phalanx of third digit of hand" EXACT [FMA:37511] synonym: "base of proximal phalanx of third finger" EXACT [FMA:37511] xref: FMA:37511 ! Proximal epiphysis of proximal phalanx of middle finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004329 ! part_of proximal phalanx of manual digit 3 xref: SCTID:263413006 ! Base of proximal phalanx of middle finger synonym: "proximal epiphysis of proximal phalanx of middle finger" NARROW SENSU [NCBITaxon:9606, FMA:37511] [Term] id: UBERON:0004442 name: proximal epiphysis of proximal phalanx of manual digit 4 def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of fourth finger" EXACT [FMA:37523] synonym: "basal epiphysis of proximal phalanx of ring finger" EXACT [FMA:37523] synonym: "base of proximal phalanx of fourth digit of hand" EXACT [FMA:37523] synonym: "base of proximal phalanx of fourth finger" EXACT [FMA:37523] synonym: "base of proximal phalanx of ring finger" EXACT [FMA:37523] xref: FMA:37523 ! Proximal epiphysis of proximal phalanx of ring finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004330 ! part_of proximal phalanx of manual digit 4 xref: SCTID:263414000 ! Base of proximal phalanx of ring finger synonym: "proximal epiphysis of proximal phalanx of ring finger" NARROW SENSU [NCBITaxon:9606, FMA:37523] [Term] id: UBERON:0004443 name: proximal epiphysis of proximal phalanx of manual digit 5 def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of little finger" EXACT [FMA:37535] synonym: "base of proximal phalanx of fifth digit of hand" EXACT [FMA:37535] synonym: "base of proximal phalanx of fifth finger" EXACT [FMA:37535] synonym: "base of proximal phalanx of little finger" EXACT [FMA:37535] xref: FMA:37535 ! Proximal epiphysis of proximal phalanx of little finger intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004331 ! part_of proximal phalanx of manual digit 5 xref: SCTID:263415004 ! Base of proximal phalanx of little finger synonym: "proximal epiphysis of proximal phalanx of little finger" NARROW SENSU [NCBITaxon:9606, FMA:37535] [Term] id: UBERON:0004444 name: proximal epiphysis of distal phalanx of manual digit 1 def: "A proximal epiphysis that is part of a distal phalanx of manual digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "base of distal phalanx of thumb" EXACT [FMA:37493] xref: FMA:37493 ! Proximal epiphysis of distal phalanx of thumb intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004337 ! part_of distal phalanx of manual digit 1 xref: SCTID:182008001 ! Base of distal phalanx of thumb synonym: "proximal epiphysis of distal phalanx of thumb" NARROW SENSU [NCBITaxon:9606, FMA:37493] [Term] id: UBERON:0004445 name: proximal epiphysis of proximal phalanx of manual digit 1 def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of thumb" EXACT [FMA:37490] synonym: "base of proximal phalanx of thumb" EXACT [FMA:37490] xref: FMA:37490 ! Proximal epiphysis of proximal phalanx of thumb intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0004338 ! part_of proximal phalanx of manual digit 1 xref: SCTID:181993001 ! Base of proximal phalanx of thumb synonym: "proximal epiphysis of proximal phalanx of thumb" NARROW SENSU [NCBITaxon:9606, FMA:37490] [Term] id: UBERON:0004446 name: epiphysis of phalanx def: "An epiphysis that is part of a phalanx [Automatically generated definition]." [OBOL:automatic] intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003221 ! phalanx xref: SCTID:280033007 ! Epiphysis of phalanx [Term] id: UBERON:0004447 name: proximal epiphysis of phalanx def: "A proximal epiphysis that is part of a phalanx [Automatically generated definition]." [OBOL:automatic] intersection_of: UBERON:0004380 ! proximal epiaphysis intersection_of: part_of UBERON:0003221 ! phalanx [Term] id: UBERON:0004448 name: distal epiphysis of phalanx def: "A distal epiphysis that is part of a phalanx [Automatically generated definition]." [OBOL:automatic] intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0003221 ! phalanx [Term] id: UBERON:0013122 name: distal epiphysis of phalanx of pes synonym: "caput phalangis (pedis)" EXACT [FMA:32890] synonym: "caput phalangis pedis" EXACT [FMA:TA] synonym: "distal end of phalanx of foot" EXACT [FMA:32890] synonym: "head of phalanx of foot" EXACT [FMA:32890] synonym: "distal epiphysis of phalanx of toe" EXACT [FMA:32890] intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001449 ! phalanx of pes xref: FMA:32890 ! distal epiphysis of phalanx of toe xref: SCTID:236801009 ! Entire head of phalanx of foot [Term] id: UBERON:0004449 ! cerebral artery name: cerebral artery def: "One of three main pairs of arteries and their branches, which irrigate the cerebrum of the brain." [Wikipedia:Cerebral_artery] xref: MA:0002562 ! cerebral artery xref: XAO:0000367 ! cerebral artery xref: GAID:484 ! cerebral artery xref: ncithesaurus:Cerebral_Artery ! Cerebral Artery xref: EHDAA2:0000233 ! cerebral artery xref: EMAPA:18613 ! cerebral artery xref: MESH:A07.231.114.228 ! cerebral artery xref: EHDAA:5294 ! cerebral artery is_a: UBERON:0001637 ! artery relationship: continuous_with UBERON:0001532 ! internal carotid artery relationship: part_of UBERON:0003709 ! circle of Willis xref: AAO:0010493 ! cerebral artery xref: SCTID:181308008 ! Entire cerebral artery property_value: external_definition "Part of the internal carotid containing many branches supplying blood to the chorioid plexuses of the brain.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010493", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of internal carotid (AAO:0010219)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010493", date_retrieved="2012-06-20"} xref: UMLS:C0007770 [Term] id: UBERON:0004450 name: gastric vein xref: MA:0002128 ! gastric vein xref: XAO:0000389 ! gastric vein xref: ncithesaurus:Gastric_Vein ! Gastric Vein is_a: UBERON:0001638 ! vein xref: AAO:0011046 ! gastric vein xref: SCTID:281060006 ! Entire gastric vein xref: UMLS:C0750610 [Term] id: UBERON:0004464 name: musculature of thorax def: "A musculature that is part of a thorax [Automatically generated definition]." [OBOL:automatic] comment: note BTO and FMA do not mean precisely the same thing here synonym: "muscle group of thorax" EXACT [FMA:71293] synonym: "muscles of thorax" EXACT [FMA:71293] synonym: "thoracic musculature" EXACT [FMA:71293] xref: FMA:71293 ! Musculature of thorax xref: BTO:0000508 ! thorax muscle (also: UBERON:0002426 'chest muscle') intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000915 ! part_of thorax synonym: "musculi thoracis" EXACT LATIN [FMA:TA, FMA:71293] synonym: "set of muscles of thorax" EXACT [FMA:71293] [Term] id: UBERON:0004465 name: musculature of neck def: "A musculature that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of neck" EXACT [FMA:71290] synonym: "muscles of neck" EXACT [FMA:71290] synonym: "neck musculature" EXACT [FMA:71290] synonym: "cervical muscles" EXACT [AAO:0000091] xref: FMA:71290 ! Musculature of neck xref: MESH:A02.633.567.650 ! neck muscle (also: UBERON:0002377 'muscle of neck') xref: AAO:0000091 ! cervical muscles intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000974 ! part_of neck synonym: "musculi cervicis" EXACT LATIN [FMA:TA, FMA:71290] synonym: "musculi colli" EXACT LATIN [FMA:TA, FMA:71290] synonym: "set of muscles of neck" EXACT [FMA:71290] [Term] id: UBERON:0004468 name: set of muscles of vertebral column def: "A musculature that is part of a vertebral column [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of vertebral column" EXACT [FMA:33061] xref: FMA:33061 ! Set of muscles of vertebral column intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001130 ! part_of vertebral column [Term] id: UBERON:0004469 name: musculature of back def: "A musculature that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of back" EXACT [FMA:71291] synonym: "muscles of back" EXACT [FMA:71291] xref: FMA:71291 ! Musculature of back intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001137 ! part_of back synonym: "musculi dorsi" EXACT LATIN [FMA:TA, FMA:71291] synonym: "set of muscles of back" EXACT [FMA:71291] [Term] id: UBERON:0001325 name: muscle of pelvis def: "Muscle (organ) which is a part of the pelvis. Examples: levator ani," [FMA:19086] subset: uberon_slim synonym: "pelvic muscle" EXACT [FMA:19086] synonym: "pelvis muscle" EXACT [] synonym: "muscle organ of pelvis" EXACT [OBOL:automatic] synonym: "pelvis muscle organ" EXACT [OBOL:automatic] xref: FMA:19086 ! Muscle of pelvis xref: MA:0000534 ! pelvis muscle is_a: UBERON:0003833 {source="MA"} ! abdominal segment muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002355 {source="FMAdef"} ! pelvis [Term] id: UBERON:0001497 name: muscle of pelvic girdle def: "A muscle organ that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic] comment: AO notes: Note that in MA, this is a subclass of pelvis muscle; in FMA this is a hindlimb muscle, but recall in FMA hindlimb includes the girdle. synonym: "pelvic girdle muscle" EXACT [] synonym: "girdle-pelvic muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of girdle-pelvic" EXACT [OBOL:automatic] synonym: "muscle organ of pelvic girdle" EXACT [OBOL:automatic] synonym: "muscle organ of pelvic girdle bone" EXACT [OBOL:automatic] synonym: "pelvic girdle bone muscle organ" EXACT [OBOL:automatic] synonym: "pelvic girdle muscle organ" EXACT [OBOL:automatic] xref: FMA:37367 ! Muscle of pelvic girdle xref: MA:0000537 ! pelvic girdle muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001271 ! pelvic girdle region relationship: part_of UBERON:0004470 ! musculature of pelvic girdle [Term] id: UBERON:0004470 name: musculature of pelvic girdle alt_id: UBERON:0005633 alt_id: UBERON:0004485 def: "A musculature that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic] comment: AO notes: we merge two FMA classes here synonym: "pelvic girdle muscle system" EXACT [EHDAA2:0001429] synonym: "muscle group of pelvic girdle" EXACT [FMA:50205] synonym: "pelvic girdle musculature" EXACT [FMA:50205] synonym: "pelvic girdle muscles" EXACT [AAO:0000427] xref: AAO:0000427 ! pelvic girdle muscles xref: FMA:50205 ! Musculature of pelvic girdle xref: EHDAA2:0001429 ! pelvic girdle muscle system xref: FMA:50248 ! Set of muscles of pelvis intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001271 ! part_of pelvic girdle region synonym: "set of muscles of pelvic girdle" EXACT [FMA:50205] [Term] id: UBERON:0004471 name: musculature of pectoral girdle def: "A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles." [UBERON:cjm] synonym: "muscle group of pectoral girdle" EXACT [FMA:33519] synonym: "pectoral girdle musculature" EXACT [FMA:33519] synonym: "pectoral girdle muscles" EXACT [AAO:0000423] xref: FMA:33519 ! Musculature of pectoral girdle xref: AAO:0000423 ! pectoral girdle muscles intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001421 ! part_of pectoral girdle region synonym: "set of muscles of pectoral girdle" EXACT [FMA:33519] [Term] id: UBERON:0008196 name: muscle of pectoral girdle def: "A muscle organ that is part of a pectoral girdle region." [OBOL:automatic] synonym: "muscle of shoulder girdle" EXACT [FMA:37347] synonym: "pectoral girdle muscle" EXACT [FMA:37347] xref: FMA:37347 ! muscle of pectoral girdle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001421 ! part_of pectoral girdle region relationship: part_of UBERON:0004471 ! musculature of pectoral girdle [Term] id: UBERON:0001495 name: pectoral muscle comment: This currently groups the major and minor muscles (which have different attachment sites) as well as the AAO structure: Muscle which is comprised of three heads. The anterior head is the portio epicoracoidea that originates on the epicoracoid cartilage and inserts on the deltoid crest of the humerus. The next more posterior head, portio sternalis, originates on the sternum and inserts in the groove next to the deltoid crest of the humerus. The most posterior head, portio abdominalis, arises from the M. rectus abdominis and inserts on the deltoid crest of the humerus subset: uberon_slim subset: grouping_class synonym: "muscle of pectoral part of chest" EXACT [FMA:37349] synonym: "muscle of pectoral region" EXACT [FMA:37349] synonym: "pectoralis muscle" RELATED [BTO:0000023] synonym: "pectoralis" RELATED [] synonym: "breast muscle" RELATED [BTO:0000023] synonym: "M. pectoralis" EXACT [AAO:0010727] xref: BTO:0000023 xref: FMA:37349 ! Pectoral muscle xref: GAID:153 ! pectoralis muscle xref: MA:0002423 ! pectoralis muscle xref: ncithesaurus:Pectoralis_Muscle ! Pectoralis Muscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6c/Pectoralis_major.png/200px-Pectoralis_major.png xref: MESH:A02.633.567.775 ! pectoralis muscle xref: AAO:0010727 ! M. pectoralis is_a: UBERON:0008196 {source="FMA"} ! muscle of pectoral girdle relationship: part_of UBERON:0004464 {source="BTO"} ! musculature of thorax relationship: develops_from UBERON:0010984 ! pectoral pre-muscle mass xref: SCTID:181621006 ! Entire pectoral muscle property_value: external_definition "Muscle which is comprised of three heads. The anterior head is the portio epicoracoidea that originates on the epicoracoid cartilage and inserts on the deltoid crest of the humerus. The next more posterior head, portio sternalis, originates on the sternum and inserts in the groove next to the deltoid crest of the humerus. The most posterior head, portio abdominalis, arises from the M. rectus abdominis and inserts on the deltoid crest of the humerus.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010727", date_retrieved="2012-06-20", source="AAO:MEJ"} xref: UMLS:C0030747 [Term] id: UBERON:0010984 ! pectoral pre-muscle mass name: pectoral pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle xref: EHDAA2:0001423 ! pectoral pre-muscle mass [Term] id: UBERON:0001100 name: pectoralis minor def: "The Pectoralis minor is a thin, triangular muscle, situated at the upper part of the chest, beneath the Pectoralis major. [WP,unvetted]." [Wikipedia:Pectoralis_minor_muscle] subset: uberon_slim synonym: "pectoralis minor muscle" EXACT [] synonym: "supracoracoideus" NARROW SENSU [] synonym: "supracoracoideus muscle" NARROW SENSU [] xref: EHDAA:8313 ! pectoralis minor xref: FMA:13109 ! Pectoralis minor xref: VHOG:0000902 ! pectoralis minor xref: MA:0002355 ! pectoralis minor xref: ncithesaurus:Pectoralis_Minor ! Pectoralis Minor xref: EHDAA2:0001425 ! pectoralis minor xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5d/Pectoralis_minor.png/200px-Pectoralis_minor.png xref: EMAPA:18180 ! pectoralis minor is_a: UBERON:0001495 {source="FMA"} ! pectoral muscle xref: SCTID:181625002 ! Entire pectoralis minor muscle subset: organ_slim synonym: "musculus pectoralis minor" RELATED LATIN [Wikipedia:Pectoralis_minor_muscle] relationship: has_muscle_insertion UBERON:0007174 {source="dbpedia", notes="medial border and superior surface of the coracoid process of the scapula"} ! medial part of scapula relationship: has_muscle_origin UBERON:0002228 {source="dbpedia", notes="third to fifth ribs near their costal cartilages"} ! rib xref: http://upload.wikimedia.org/wikipedia/commons/5/5d/Pectoralis_minor.png xref: UMLS:C0224347 [Term] id: UBERON:0002381 name: pectoralis major def: "The pectoralis major is a thick, fan-shaped muscle, situated at the upper front of the chest wall. It makes up the bulk of the chest muscles in the male and lies under the breast in the female. Underneath the pectoralis major is the pectoralis minor, a thin, triangular muscle. [WP,unvetted]." [Wikipedia:Pectoralis_major_muscle] subset: uberon_slim synonym: "pectoralis major muscle structure" EXACT [SCTID:60005003] synonym: "pectoralis major muscle" EXACT [] xref: EHDAA:8311 ! pectoralis major xref: FMA:9627 ! Pectoralis major xref: VHOG:0000895 ! pectoralis major xref: MA:0002354 ! pectoralis major xref: ncithesaurus:Pectoralis_Major ! Pectoralis Major xref: EHDAA2:0001424 ! pectoralis major xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6c/Pectoralis_major.png/200px-Pectoralis_major.png xref: EMAPA:18179 ! pectoralis major is_a: UBERON:0001495 {source="FMA"} ! pectoral muscle xref: SCTID:60005003 ! Pectoralis major muscle structure xref: SCTID:181624003 ! Entire pectoralis major muscle subset: organ_slim synonym: "Musculus pectoralis major" RELATED LATIN [Wikipedia:Pectoralis_major_muscle] relationship: has_muscle_origin UBERON:0001105 {source="dbpedia", notes="anterior surface of the medial half of the clavicle"} ! clavicle relationship: has_muscle_origin UBERON:0000975 {source="dbpedia", notes="anterior surface of the sternum and the superior six costal cartilages and the aponeurosis of the external oblique muscle"} ! sternum relationship: has_muscle_insertion UBERON:0000976 {source="dbpedia", notes="Lateral lip of intertubercular groove of the humerus"} ! humerus relationship: innervated_by UBERON:0003726 {source="dbpedia", notes="lateral pectoral nerve and medial pectoral nerveClavicular head: C5 and C6Sternocostal head: C7 C8 and T1"} ! thoracic nerve xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Pectoralis_major.png xref: UMLS:C0585574 [Term] id: UBERON:0008779 name: subclavius def: "The Subclavius is a small triangular muscle, placed between the clavicle and the first rib. Along with the pectoralis major and pectoralis minor muscles, the subclavius muscle makes up the anterior wall of the axilla." [Wikipedia:Subclavius_muscle] synonym: "subclavicular muscle" RELATED [Wikipedia:Subclavius_muscle] is_a: UBERON:0001495 {source="FMA"} ! pectoral muscle xref: FMA:13410 ! subclavius xref: ncithesaurus:Subclavius ! Subclavius relationship: has_muscle_origin UBERON:0004601 {source="dbpedia"} ! rib 1 synonym: "musculus subclavius" RELATED LATIN [Wikipedia:Subclavius_muscle] relationship: has_muscle_insertion UBERON:0001105 {source="dbpedia", notes="subclavian groove of clavicle"} ! clavicle xref: http://upload.wikimedia.org/wikipedia/commons/a/a2/Gray411subclavius.png xref: UMLS:C0224348 [Term] id: UBERON:0004472 name: musculature of chest def: "A musculature that is part of a chest [Automatically generated definition]." [OBOL:automatic] synonym: "chest musculature" EXACT [FMA:74779] xref: FMA:74779 ! Musculature of chest intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001443 ! part_of chest synonym: "set of muscles of chest" EXACT [FMA:74779] [Term] id: UBERON:0004474 name: musculature of arm def: "A musculature that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "arm musculature" EXACT [FMA:50202] synonym: "muscle group of arm" EXACT [FMA:50202] xref: FMA:50202 ! Musculature of arm intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001460 ! part_of arm synonym: "set of muscles of arm" EXACT [FMA:50202] [Term] id: UBERON:0004475 name: musculature of hip def: "A musculature that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "hip musculature" EXACT [FMA:50227] synonym: "muscle group of hip" EXACT [FMA:50227] xref: FMA:50227 ! Musculature of hip intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001464 ! part_of hip synonym: "set of muscles of hip" EXACT [FMA:50227] [Term] id: UBERON:0004476 name: musculature of shoulder def: "A musculature that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of shoulder" EXACT [FMA:50220] xref: FMA:50220 ! Musculature of shoulder intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001467 ! part_of shoulder synonym: "set of muscles of shoulder" EXACT [FMA:50220] [Term] id: UBERON:0004477 name: tongue musculature def: "A musculature that is part of a tongue [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of tongue" EXACT [FMA:71289] synonym: "muscles of tongue" EXACT [FMA:71289] xref: FMA:71289 ! set of muscles of tongue synonym: "set of muscles of tongue" EXACT [FMA:71289] intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001723 ! part_of tongue synonym: "musculi linguae" EXACT LATIN [FMA:TA, FMA:71289] [Term] id: UBERON:0004478 name: musculature of larynx def: "A musculature that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "laryngeal muscles" EXACT [FMA:46616] synonym: "laryngeal muscles set" EXACT [FMA:46616] synonym: "muscle group of larynx" EXACT [FMA:46616] xref: FMA:264611 ! Musculature of larynx xref: FMA:46616 ! Set of laryngeal muscles xref: MESH:A02.633.567.500 ! laryngeal muscle (also: UBERON:0001568 'muscle of larynx') intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001737 ! larynx intersection_of: part_of UBERON:0001737 ! part_of larynx synonym: "set of muscles of larynx" EXACT [FMA:264611] synonym: "set of laryngeal muscles" EXACT [FMA:46616] [Term] id: UBERON:0004479 name: musculature of trunk def: "A musculature that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of trunk" EXACT [FMA:50187] xref: FMA:50187 ! Musculature of trunk xref: EFO:0003531 ! trunk musculature (also: UBERON:0001774 'muscle of trunk') xref: AAO:0011572 ! trunk musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002100 ! part_of trunk synonym: "set of muscles of trunk" EXACT [FMA:50187] [Term] id: UBERON:0004480 name: musculature of limb alt_id: UBERON:0005635 def: "A musculature that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "limb muscle system" EXACT [EHDAA2:0000995] synonym: "limb musculature" EXACT [FMA:50188] synonym: "muscle group of limb" EXACT [FMA:50188] xref: FMA:50188 ! Musculature of limb xref: EHDAA2:0000995 ! limb muscle system intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002101 ! part_of limb synonym: "set of muscles of limb" EXACT [FMA:50188] [Term] id: UBERON:0004481 name: musculature of upper limb def: "A musculature that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "muscles of upper limb" EXACT [FMA:71296] synonym: "upper limb musculature" EXACT [FMA:71296] xref: FMA:71296 ! Musculature of upper limb intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002102 ! part_of forelimb synonym: "musculi membri superioris" EXACT LATIN [FMA:TA, FMA:71296] synonym: "set of muscles of upper limb" EXACT [FMA:71296] [Term] id: UBERON:0004482 name: musculature of lower limb def: "A musculature that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "muscles of lower limb" EXACT [FMA:71297] xref: FMA:71297 ! Musculature of lower limb intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002103 ! part_of hindlimb synonym: "musculi membri inferioris" EXACT LATIN [FMA:TA, FMA:71297] [Term] id: UBERON:0004483 name: iliocostalis musculature def: "A musculature that is part of a iliocostalis [Automatically generated definition]." [OBOL:automatic] synonym: "iliocostalis muscle group" EXACT [FMA:33062] synonym: "iliocostalis muscles set" EXACT [FMA:33062] synonym: "set of iliocostalis muscles" EXACT [FMA:33062] xref: FMA:33062 ! set of iliocostalis muscles intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002251 ! part_of iliocostalis [Term] id: UBERON:0004484 name: splenius musculature def: "A musculature that is part of a splenius [Automatically generated definition]." [OBOL:automatic] synonym: "splenius muscle group" EXACT [FMA:22596] synonym: "splenius muscles set" EXACT [FMA:22596] synonym: "set of splenius muscles" EXACT [FMA:22596] xref: FMA:22596 ! set of splenius muscles intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002252 ! part_of splenius [Term] id: UBERON:0004486 name: musculature of perineum def: "A musculature that is part of a perineum [Automatically generated definition]." [OBOL:automatic] synonym: "perineal muscles" EXACT [FMA:71295] synonym: "perineal muscles set" EXACT [FMA:71295] xref: FMA:71295 ! Musculature of perineum xref: EMAPA:18923 ! muscle of perineal body of gut intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002356 ! perineum synonym: "musculi perinei" EXACT LATIN [FMA:TA, FMA:71295] synonym: "set of perineal muscles" EXACT [FMA:71295] [Term] id: UBERON:0004487 name: musculature of forearm def: "A musculature that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of forearm" EXACT [FMA:39089] xref: FMA:39089 ! Musculature of forearm intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002386 ! part_of lower arm synonym: "set of muscles of forearm" EXACT [FMA:39089] [Term] id: UBERON:0004488 name: musculature of pes def: "A musculature that is part of a foot [Automatically generated definition]." [OBOL:automatic] synonym: "foot musculature" EXACT [FMA:50214] synonym: "muscle group of foot" EXACT [FMA:50214] xref: FMA:50214 ! Musculature of foot intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002387 ! part_of pes synonym: "musculature of foot" EXACT [FMA:50214] synonym: "set of muscles of foot" EXACT [FMA:50214] [Term] id: UBERON:0004489 name: musculature of manus def: "A musculature that is part of a manus [Automatically generated definition]." [OBOL:automatic] synonym: "hand musculature" EXACT [FMA:42368] synonym: "muscle group of hand" EXACT [FMA:42368] xref: FMA:42368 ! Musculature of hand intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002398 ! part_of manus synonym: "musculature of hand" EXACT [FMA:42368] synonym: "set of muscles of hand" EXACT [FMA:42368] [Term] id: UBERON:0004490 name: cardiac muscle tissue of atrium def: "A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]." [OBOL:automatic] xref: FMA:7283 ! Cardiac muscle tissue of atrium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002081 ! cardiac atrium [Term] id: UBERON:0004491 name: cardiac muscle tissue of interatrial septum def: "A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]." [OBOL:automatic] xref: FMA:84083 ! Cardiac muscle tissue of interatrial septum intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002085 ! part_of interatrial septum [Term] id: UBERON:0004492 name: cardiac muscle tissue of cardiac septum def: "A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]." [OBOL:automatic] xref: FMA:226279 ! Cardiac muscle tissue of cardiac septum intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002099 ! part_of cardiac septum [Term] id: UBERON:0004494 name: cardiac muscle tissue of papillary muscle def: "A portion of cardiac muscle tissue that is part of a papillary muscle [Automatically generated definition]." [OBOL:automatic] xref: FMA:84425 ! Cardiac muscle tissue of papillary muscle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002494 ! part_of papillary muscle [Term] id: UBERON:0004495 name: skeletal muscle tissue of diaphragm def: "A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]." [OBOL:automatic] xref: FMA:261898 ! Skeletal muscle tissue of diaphragm intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001103 ! diaphragm [Term] id: UBERON:0004496 name: skeletal muscle tissue of iliacus def: "A portion of skeletal muscle tissue that is part of a iliacus [Automatically generated definition]." [OBOL:automatic] xref: FMA:261992 ! Skeletal muscle tissue of iliacus intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001369 ! iliacus [Term] id: UBERON:0004497 name: skeletal muscle tissue of gluteus maximus def: "A portion of skeletal muscle tissue that is part of a gluteus maximus [Automatically generated definition]." [OBOL:automatic] xref: FMA:261980 ! Skeletal muscle tissue of gluteus maximus intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001370 ! gluteus maximus [Term] id: UBERON:0004498 name: skeletal muscle tissue of quadriceps femoris def: "A portion of skeletal muscle tissue that is part of a quadriceps femoris [Automatically generated definition]." [OBOL:automatic] xref: FMA:261998 ! Skeletal muscle tissue of quadriceps femoris intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001377 ! quadriceps femoris [Term] id: UBERON:0004499 name: skeletal muscle tissue of tibialis anterior def: "A portion of skeletal muscle tissue that is part of a tibialis anterior [Automatically generated definition]." [OBOL:automatic] xref: FMA:262004 ! Skeletal muscle tissue of tibialis anterior intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001385 ! tibialis anterior [Term] id: UBERON:0004500 name: skeletal muscle tissue of deltoid def: "A portion of skeletal muscle tissue that is part of a deltoid [Automatically generated definition]." [OBOL:automatic] xref: FMA:261732 ! Skeletal muscle tissue of deltoid intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001476 ! deltoid [Term] id: UBERON:0004501 name: skeletal muscle tissue of teres major def: "A portion of skeletal muscle tissue that is part of a teres major [Automatically generated definition]." [OBOL:automatic] xref: FMA:261962 ! Skeletal muscle tissue of teres major intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001478 ! teres major [Term] id: UBERON:0004502 name: skeletal muscle tissue of biceps brachii def: "A portion of skeletal muscle tissue that is part of a biceps brachii [Automatically generated definition]." [OBOL:automatic] xref: FMA:261974 ! Skeletal muscle tissue of biceps brachii intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001507 ! biceps brachii [Term] id: UBERON:0004503 name: skeletal muscle tissue of digastric def: "A portion of skeletal muscle tissue that is part of a digastric [Automatically generated definition]." [OBOL:automatic] xref: FMA:261872 ! Skeletal muscle tissue of digastric intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001562 ! digastric [Term] id: UBERON:0004504 name: skeletal muscle tissue of mylohyoid def: "A portion of skeletal muscle tissue that is part of a mylohyoid [Automatically generated definition]." [OBOL:automatic] xref: FMA:261878 ! Skeletal muscle tissue of mylohyoid intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001564 ! mylohyoid [Term] id: UBERON:0004505 name: skeletal muscle tissue of orbicularis oculi def: "A portion of skeletal muscle tissue that is part of a orbicularis oculi [Automatically generated definition]." [OBOL:automatic] xref: FMA:261812 ! Skeletal muscle tissue of orbicularis oculi intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001578 ! orbicularis oculi [Term] id: UBERON:0004506 name: skeletal muscle tissue of masseter def: "A portion of skeletal muscle tissue that is part of a masseter [Automatically generated definition]." [OBOL:automatic] xref: FMA:261824 ! Skeletal muscle tissue of masseter intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001597 ! masseter [Term] id: UBERON:0004507 name: skeletal muscle tissue of temporalis def: "A portion of skeletal muscle tissue that is part of a temporalis [Automatically generated definition]." [OBOL:automatic] xref: FMA:261740 ! Skeletal muscle tissue of temporalis intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001598 ! temporalis [Term] id: UBERON:0004508 name: skeletal muscle tissue of levator palpebrae superioris def: "A portion of skeletal muscle tissue that is part of a levator palpebrae superioris [Automatically generated definition]." [OBOL:automatic] xref: FMA:261782 ! Skeletal muscle tissue of levator palpebrae superioris intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001604 ! levator palpebrae superioris [Term] id: UBERON:0004509 name: skeletal muscle tissue of trapezius def: "A portion of skeletal muscle tissue that is part of a trapezius [Automatically generated definition]." [OBOL:automatic] xref: FMA:261938 ! Skeletal muscle tissue of trapezius intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002380 ! trapezius [Term] id: UBERON:0004510 name: skeletal muscle tissue of pectoralis major def: "A portion of skeletal muscle tissue that is part of a pectoralis major [Automatically generated definition]." [OBOL:automatic] xref: FMA:261968 ! Skeletal muscle tissue of pectoralis major intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002381 ! pectoralis major [Term] id: UBERON:0004511 name: skeletal muscle tissue of rectus abdominis def: "A portion of skeletal muscle tissue that is part of a rectus abdominis [Automatically generated definition]." [OBOL:automatic] xref: FMA:261924 ! Skeletal muscle tissue of rectus abdominis intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002382 ! rectus abdominis [Term] id: UBERON:0004512 name: skeletal muscle tissue of supraspinatus def: "A portion of skeletal muscle tissue that is part of a supraspinatus [Automatically generated definition]." [OBOL:automatic] xref: FMA:261956 ! Skeletal muscle tissue of supraspinatus intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002383 ! supraspinatus [Term] id: UBERON:0004513 name: skeletal muscle tissue of internal intercostal muscle def: "A portion of skeletal muscle tissue that is part of a internal intercostal muscle [Automatically generated definition]." [OBOL:automatic] xref: FMA:261888 ! Skeletal muscle tissue of internal intercostal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002403 ! internal intercostal muscle [Term] id: UBERON:0004514 name: skeletal muscle tissue of transversus thoracis def: "A portion of skeletal muscle tissue that is part of a transversus thoracis [Automatically generated definition]." [OBOL:automatic] xref: FMA:261892 ! Skeletal muscle tissue of transversus thoracis intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002404 ! transversus thoracis [Term] id: UBERON:0004515 name: smooth muscle tissue of bronchiole def: "A portion of smooth muscle tissue that is part of a bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "smooth muscle tissue of lobular bronchiole" EXACT [FMA:261081] xref: FMA:261045 ! Smooth muscle tissue of bronchiole xref: FMA:261081 ! Smooth muscle tissue of lobular bronchiole intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002186 ! bronchiole [Term] id: UBERON:0004516 name: smooth muscle tissue of terminal bronchiole def: "A portion of smooth muscle tissue that is part of a terminal bronchiole [Automatically generated definition]." [OBOL:automatic] xref: FMA:261051 ! Smooth muscle tissue of terminal bronchiole intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002187 ! terminal bronchiole [Term] id: UBERON:0004517 name: smooth muscle tissue of respiratory bronchiole def: "A portion of smooth muscle tissue that is part of a respiratory bronchiole [Automatically generated definition]." [OBOL:automatic] xref: FMA:261055 ! Smooth muscle tissue of respiratory bronchiole intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002188 ! respiratory bronchiole [Term] id: UBERON:0004518 name: muscle of vertebral column def: "A muscle that is attached to a vertebra of the vertebral column." [UBERON:cjm] synonym: "vertebral column muscle" EXACT [FMA:22594] xref: FMA:22594 ! Muscle of vertebral column intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0002412 ! vertebra [Term] id: UBERON:0008549 name: prevertebral muscle def: "The prevertebral muscles are the muscles located between the prevertebral fascia (older definition) and the vertebral column, i.e. , the longus capitis and longus colli muscles. It also includes the recti capitis anterior and lateralis." [Wikipedia:Prevertebral_muscles] synonym: "flexor muscle of vertebral column" EXACT [FMA:32514] is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column xref: FMA:32514 ! prevertebral muscle xref: http://upload.wikimedia.org/wikipedia/commons/b/b0/Prevertebral_muscles.png [Term] id: UBERON:0002379 name: perineal muscle def: "A muscle organ that is part of a perineum [Automatically generated definition]." [OBOL:automatic] comment: This class was created automatically from a combination of ontologies synonym: "muscle of perineum" EXACT [] synonym: "muscle organ of perineal region" EXACT [OBOL:automatic] synonym: "muscle organ of perineum" EXACT [OBOL:automatic] synonym: "perineal region muscle organ" EXACT [OBOL:automatic] synonym: "perineum muscle organ" EXACT [OBOL:automatic] xref: FMA:9623 ! Perineal muscle xref: MA:0000538 ! perineal muscle xref: ncithesaurus:Perineal_Muscle ! Perineal Muscle is_a: UBERON:0001325 ! muscle of pelvis intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002356 ! perineum xref: UMLS:C0224382 [Term] id: UBERON:0004519 name: muscle of anal triangle synonym: "anal triangle muscle" EXACT [FMA:77304] xref: FMA:77304 ! Muscle of anal triangle is_a: UBERON:0002379 {source="FMA"} ! perineal muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0006867 ! anal part of perineum [Term] id: UBERON:0008715 name: muscle tissue of prostate synonym: "prostate muscle tissue" EXACT [OBOL:automatic] synonym: "prostate gland muscle tissue" EXACT [OBOL:automatic] intersection_of: UBERON:0002385 ! muscle tissue intersection_of: part_of UBERON:0002367 ! part_of prostate xref: ncithesaurus:Prostatic_Muscular_Tissue ! Prostatic Muscular Tissue def: "A muscle tissue that is part of a prostate gland." [OBOL:automatic] xref: UMLS:C1183911 [Term] id: UBERON:0004520 name: striated muscle tissue of prostate def: "A portion of striated muscle tissue that is part of a prostate gland [Automatically generated definition]." [OBOL:automatic] xref: FMA:45716 ! Striated muscle tissue of prostate is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0002036 ! striated muscle tissue intersection_of: part_of UBERON:0002367 ! part_of prostate [Term] id: UBERON:0004243 name: prostate gland smooth muscle def: "A portion of smooth muscle tissue that is part of a prostate gland [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of prostate" EXACT [OBOL:automatic] synonym: "involuntary muscle of prostate gland" EXACT [OBOL:automatic] synonym: "non-striated muscle of prostate" EXACT [OBOL:automatic] synonym: "non-striated muscle of prostate gland" EXACT [OBOL:automatic] synonym: "prostate gland involuntary muscle" EXACT [OBOL:automatic] synonym: "prostate gland non-striated muscle" EXACT [OBOL:automatic] synonym: "prostate gland smooth muscle tissue" EXACT [OBOL:automatic] synonym: "prostate involuntary muscle" EXACT [OBOL:automatic] synonym: "prostate non-striated muscle" EXACT [OBOL:automatic] synonym: "prostate smooth muscle" EXACT [OBOL:automatic] synonym: "prostate smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of prostate" EXACT [OBOL:automatic] synonym: "smooth muscle of prostate gland" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of prostate" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of prostate gland" EXACT [OBOL:automatic] synonym: "muscular tissue of prostate" EXACT [FMA:74245] xref: MA:0001741 ! prostate gland smooth muscle xref: FMA:74245 ! Smooth muscle tissue of prostate xref: BTO:0003159 ! prostate gland smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002367 ! prostate relationship: has_part CL:1000487 {source="FMA"} ! smooth muscle fiber of prostate synonym: "substantia muscularis prostatae" EXACT LATIN [FMA:TA, FMA:74245] [Term] id: UBERON:0004521 name: vasculature of muscle organ def: "A vasculature that is part of a muscle organ [Automatically generated definition]." [OBOL:automatic] synonym: "muscular organ vasculature" EXACT [FMA:87123] xref: FMA:87123 ! Vasculature of muscle organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001630 ! part_of muscle organ [Term] id: UBERON:0004522 name: vasculature of musculoskeletal system def: "A vasculature that is part of a musculoskeletal system [Automatically generated definition]." [OBOL:automatic] xref: FMA:239607 ! Vasculature of musculoskeletal system intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002204 ! part_of musculoskeletal system [Term] id: UBERON:0004525 name: cardiac muscle tissue of trabecula carnea of right ventricle def: "A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic] xref: FMA:84429 ! Cardiac muscle tissue of trabecula carnea of right ventricle intersection_of: UBERON:0003452 ! trabecula carnea cardiac muscle tissue intersection_of: part_of UBERON:0002080 ! part_of right ventricle relationship: part_of UBERON:0006570 {is_inferred="true", source="reference_0000032"} ! trabecula carnea of right ventricle [Term] id: UBERON:0004526 name: cardiac muscle tissue of trabecula carnea of left ventricle def: "A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic] xref: FMA:84430 ! Cardiac muscle tissue of trabecula carnea of left ventricle intersection_of: UBERON:0003452 ! trabecula carnea cardiac muscle tissue intersection_of: part_of UBERON:0002084 ! part_of left ventricle relationship: part_of UBERON:0006571 {is_inferred="true", source="reference_0000032"} ! trabecula carnea of left ventricle [Term] id: UBERON:0004529 ! anatomical projection name: anatomical projection def: "a projection or outgrowth of tissue from a larger body or organ." [Wikipedia:Process_(anatomy)] synonym: "projection" EXACT [] synonym: "process" BROAD [VSAO:0000180] synonym: "process of organ" NARROW [] synonym: "anatomical process" BROAD [] synonym: "organ process" NARROW [] synonym: "flange" NARROW [VSAO:0000180] synonym: "flanges" NARROW PLURAL [VSAO:0000180] synonym: "lamella" NARROW [VSAO:0000180] synonym: "lamellae" NARROW PLURAL [VSAO:0000180] synonym: "lamina" NARROW [VSAO:0000180] synonym: "laminae" NARROW [VSAO:0000180] synonym: "processes" NARROW PLURAL [VSAO:0000180] synonym: "projection" NARROW [VSAO:0000180] synonym: "projections" NARROW PLURAL [VSAO:0000180] synonym: "ridge" NARROW [VSAO:0000180] synonym: "ridges" NARROW PLURAL [VSAO:0000180] synonym: "shelf" NARROW [VSAO:0000180] synonym: "shelves" NARROW PLURAL [VSAO:0000180] xref: HAO:0000822 ! process xref: FMA:67601 ! Process of organ is_a: UBERON:0000063 ! organ segment subset: upper_level xref: AAO:0010278 ! process xref: XAO:0004020 ! process xref: VSAO:0000180 ! process xref: TAO:0001834 ! process property_value: external_definition "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, or tissue.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010278", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.[VSAO]" xsd:string {ontology="VSAO", external_class="VSAO:0000180", date_retrieved="2012-08-14", source="TAO:curator"} property_value: external_definition "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001834", date_retrieved="2012-08-14", source="TAO:wd"} xref: galen:Ridge ! ridge [Term] id: UBERON:0004530 ! bony projection name: bony projection def: "Anatomical projection that is composed of bone tissue." [VSAO:wd] subset: vertebrate_core synonym: "projection of bone" EXACT [] synonym: "bone process" EXACT [FMA:75433] xref: ZFA:0001637 ! bony projection xref: FMA:75433 ! Bone process intersection_of: UBERON:0004529 ! anatomical projection intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue [Term] id: UBERON:0011769 ! cartilaginous projection name: cartilaginous projection def: "Anatomical projection that is composed of cartilage tissue." [VSAO:wd] synonym: "cartilage process" EXACT [] synonym: "cartilaginous process" EXACT [] intersection_of: UBERON:0004529 ! anatomical projection intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0004531 ! left side of organism name: obsolete left side of organism is_obsolete: true [Term] id: UBERON:0004532 ! right side of organism name: obsolete right side of organism is_obsolete: true [Term] id: UBERON:0004538 ! left kidney name: left kidney def: "A kidney that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] xref: FMA:7205 ! Left kidney xref: MA:0001655 ! left kidney intersection_of: UBERON:0002113 ! kidney intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: ncithesaurus:Left_Kidney ! Left Kidney xref: SCTID:362209008 ! Entire left kidney xref: UMLS:C0227614 [Term] id: UBERON:0004539 ! right kidney name: right kidney def: "A kidney that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] xref: FMA:7204 ! Right kidney xref: MA:0001683 ! right kidney intersection_of: UBERON:0002113 ! kidney intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism xref: ncithesaurus:Right_Kidney ! Right Kidney xref: SCTID:362208000 ! Entire right kidney xref: UMLS:C0227613 [Term] id: UBERON:0004544 name: epididymis epithelium def: "A simple columnar epithelium that is part of a epididymis [Automatically generated definition]." [OBOL:automatic] synonym: "Epididymis epithelium" EXACT [FMA:19153] synonym: "epithelium of epididymis" EXACT [FMA:19153] xref: FMA:19153 ! Epithelium of epididymis xref: MA:0002825 ! epididymis epithelium xref: EMAPA:30445 ! epithelium of epididymis intersection_of: UBERON:0000485 ! simple columnar epithelium intersection_of: part_of UBERON:0001301 ! epididymis [Term] id: UBERON:0004545 name: external capsule def: "External capsule is an organ subdivision of the telencephalon which is made up primarily of myelinated axonal neural tissue (white matter). The external capsule is a sheet-like fiber bundle located lateral to the to the putamen and globus pallidus which projects dorsally to the white matter underlying the cerebral cortex[FMA]." [FMA:61959, Wikipedia:External_capsule] xref: FMA:61959 ! External capsule xref: MA:0002896 ! external capsule xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/91/Telencephalon-Horiconatal.jpg/200px-Telencephalon-Horiconatal.jpg is_a: UBERON:0002437 ! cerebral white matter xref: ncithesaurus:External_Capsule ! External Capsule xref: SCTID:279300007 ! External capsule xref: NIF_GrossAnatomy:nlx_anat_1010013 ! External capsule synonym: "capsula externa" RELATED LATIN [Wikipedia:External_capsule] xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Telencephalon-Horiconatal.jpg xref: UMLS:C0152345 [Term] id: UBERON:0004546 name: cribriform plate def: "The cribriform plate of the ethmoid bone (horizontal lamina) is received into the ethmoidal notch of the frontal bone and roofs in the nasal cavities. Projecting upward from the middle line of this plate is a thick, smooth, triangular process, the crista galli, so called from its resemblance to a cock's comb. The long thin posterior border of the crista galli serves for the attachment of the falx cerebri. Its anterior border, short and thick, articulates with the frontal bone, and presents two small projecting alæ, which are received into corresponding depressions in the frontal bone and complete the foramen cecum. Its sides are smooth, and sometimes bulging from the presence of a small air sinus in the interior. On either side of the crista galli, the cribriform plate is narrow and deeply grooved; it supports the olfactory bulb and is perforated by foramina for the passage of the olfactory nerves. The foramina in the middle of the groove are small and transmit the nerves to the roof of the nasal cavity; those at the medial and lateral parts of the groove are larger—the former transmit the nerves to the upper part of the nasal septum, the latter those to the superior nasal concha. At the front part of the cribriform plate, on either side of the crista galli, is a small fissure which is occupied by a process of dura mater. Lateral to this fissure is a notch or foramen which transmits the nasociliary nerve; from this notch a groove extends backward to the anterior ethmoidal foramen. [WP,unvetted]." [Wikipedia:Cribriform_plate] synonym: "cribiform plate of ethmoid bone" EXACT [Wikipedia:Cribriform_plate] synonym: "ethmoid bone lamina cribrosa" RELATED [BTO:0004141] synonym: "lamina cribrosa of ethmoid bone" RELATED [BTO:0004141] xref: FMA:52890 ! Cribriform plate xref: MA:0002898 ! cribriform plate xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/93/Gray149.png/200px-Gray149.png xref: BTO:0004141 ! cribriform plate xref: EMAPA:19201 ! cribriform plate is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001679 {source="MA"} ! ethmoid xref: SCTID:282814006 ! Entire cribriform plate synonym: "lamina cribrosa ossis ethmoidalis" RELATED LATIN [Wikipedia:Cribriform_plate] xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Gray149.png [Term] id: UBERON:0004548 name: left eye def: "An eye that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "left orbital part of face" NARROW [FMA:54450] synonym: "left orbital region" NARROW [FMA:54450] synonym: "left eyeball" EXACT [FMA:12515] xref: FMA:12515 ! left eyeball xref: MA:0002949 ! left eye intersection_of: UBERON:0000970 ! eye intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:362503005 ! Entire left eye [Term] id: UBERON:0004549 name: right eye def: "An eye that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "right orbital part of face" NARROW [FMA:54449] synonym: "right orbital region" NARROW [FMA:54449] synonym: "right eyeball" EXACT [FMA:12514] xref: FMA:12514 ! right eyeball xref: MA:0002950 ! right eye intersection_of: UBERON:0000970 ! eye intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:362502000 ! Entire right eye [Term] id: UBERON:0010223 ! left pupil name: left pupil synonym: "pupil of left eye" EXACT [FMA:58254] intersection_of: UBERON:0001771 ! pupil intersection_of: part_of UBERON:0004548 ! left eye xref: FMA:58254 ! left pupil xref: SCTID:368597006 ! Entire pupil of left eye def: "A pupil that is part of a left eye." [OBOL:automatic] [Term] id: UBERON:0010224 ! right pupil name: right pupil synonym: "pupil of right eye" EXACT [FMA:58253] intersection_of: UBERON:0001771 ! pupil intersection_of: part_of UBERON:0004549 ! right eye xref: FMA:58253 ! right pupil xref: SCTID:368575009 ! Entire pupil of right eye def: "A pupil that is part of a right eye." [OBOL:automatic] [Term] id: UBERON:0004552 ! digital artery name: digital artery def: "An artery that is part of a digit [Automatically generated definition]." [OBOL:automatic] comment: check part_of - do we need term for digit + metacarpal/tarsal bones? xref: MA:0001941 ! digital artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0002544 ! digit xref: SCTID:181335004 ! Entire digital artery [Term] id: UBERON:0006163 ! dorsal digital artery name: dorsal digital artery def: "." [Wikipedia:Dorsal_digital_arteries#] comment: Note Wikipedia article refers to manual dorsal digital artery synonym: "dorsal digital arteries" EXACT [FMA:70801] synonym: "dorsal digital arteries set" EXACT [FMA:70801] xref: FMA:70801 ! set of dorsal digital arteries is_a: UBERON:0004552 ! digital artery synonym: "arteriae digitales dorsales" EXACT LATIN [FMA:TA, FMA:70801] synonym: "set of dorsal digital arteries" RELATED [FMA:70801] [Term] id: UBERON:0006145 ! dorsal digital artery of pes name: dorsal digital artery of pes def: "The dorsal digital arteries of foot are small arteries which supply the toes." [Wikipedia:Dorsal_digital_arteries_of_foot] xref: FMA:44660 ! dorsal digital artery of foot intersection_of: UBERON:0006163 ! dorsal digital arteries intersection_of: part_of UBERON:0002103 ! hindlimb xref: SCTID:230173000 ! Entire dorsal digital artery of foot synonym: "arteriae digitales dorsales pedis" RELATED LATIN [Wikipedia:Dorsal_digital_arteries_of_foot] xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Gray553.png synonym: "dorsal digital artery of foot" EXACT [FMA:44660] [Term] id: UBERON:0006146 ! dorsal digital artery of manus name: dorsal digital artery of manus def: "Dorsal digital arteries arise from the bifurcation of dorsal metacarpal arteries. They travel along the sides and dorsal aspects of the phalanges of the middle finger, ring finger, and little finger. They communicate with the proper palmar digital arteries. They run with the dorsal digital nerves of ulnar nerve and dorsal digital nerves of radial nerve." [Wikipedia:Dorsal_digital_arteries] synonym: "dorsal digital artery" BROAD [Wikipedia:Dorsal_digital_arteries] synonym: "dorsal digital artery of hand" EXACT [] intersection_of: UBERON:0006163 ! dorsal digital arteries intersection_of: part_of UBERON:0002102 ! forelimb xref: SCTID:91793005 ! Entire dorsal digital artery of hand synonym: "arteriae digitales dorsales manus" RELATED LATIN [Wikipedia:Dorsal_digital_arteries] relationship: part_of UBERON:0002389 {source="reference_0000032"} ! manual digit [Term] id: UBERON:0006164 name: forelimb common dorsal digital arteries synonym: "wing common dorsal digital arteries" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: MA:0001954 ! forelimb common dorsal digital arteries is_a: UBERON:0006146 ! dorsal digital artery of manus [Term] id: UBERON:0006165 name: median dorsal digital artery for digit 1 synonym: "median dorsal digital artery for digit 01" EXACT [MA:0001955] xref: MA:0001955 ! median dorsal digital artery for digit 01 is_a: UBERON:0006146 ! dorsal digital artery of manus [Term] id: UBERON:0006166 name: lateral dorsal digital artery for digit 5 synonym: "lateral dorsal digital artery for digit 05" EXACT [MA:0001956] xref: MA:0001956 ! lateral dorsal digital artery for digit 05 is_a: UBERON:0006146 ! dorsal digital artery of manus [Term] id: UBERON:0006167 name: forelimb proper dorsal digital arteries synonym: "wing proper dorsal digital arteries" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: MA:0001958 ! forelimb proper dorsal digital arteries is_a: UBERON:0006146 ! dorsal digital artery of manus [Term] id: UBERON:0006168 name: hindlimb common dorsal digital arteries xref: MA:0001965 ! hindlimb common dorsal digital arteries is_a: UBERON:0006145 ! dorsal digital artery of pes [Term] id: UBERON:0006169 name: hindlimb proper dorsal digital arteries xref: MA:0001967 ! hindlimb proper dorsal digital arteries is_a: UBERON:0006145 ! dorsal digital artery of pes [Term] id: UBERON:0004553 ! forelimb digital artery name: forelimb digital artery def: "A digital artery that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "wing digital artery" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "forelimb digital arteries" EXACT [MA:0001953] synonym: "digital artery of manus" EXACT [] xref: MA:0001953 ! forelimb digital arteries xref: SCTID:265791006 ! Entire digital artery of hand intersection_of: UBERON:0004552 ! digital artery intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002389 {is_inferred="true", source="reference_0000032"} ! manual digit [Term] id: UBERON:0006141 ! palmar digital artery name: palmar digital artery is_a: UBERON:0004553 ! forelimb digital artery [Term] id: UBERON:0001410 ! common palmar digital artery name: common palmar digital artery def: "Three common palmar digital arteries arise from the convexity of the superficial palmar arch and proceed distally on the second, third, and fourth lumbricales muscles." [Wikipedia:Common_palmar_digital_artery] comment: the MA term, even though plural, represents the singular, as it is an isa child of artery subset: uberon_slim synonym: "common palmar digital arteries" EXACT [] xref: FMA:22852 ! Common palmar digital artery xref: MA:0001957 ! common palmar digital arteries xref: ncithesaurus:Common_Palmar_Digital_Artery ! Common Palmar Digital Artery is_a: UBERON:0006141 ! palmar digital artery xref: SCTID:38396009 ! Entire common palmar digital artery xref: UMLS:C0226446 [Term] id: UBERON:0006137 name: proper palmar digital artery def: "The proper palmar digital arteries travel along the sides of the phalanges (along the contiguous sides of the index, middle, ring, and little fingers), each artery lying just below its corresponding digital nerve. Alternative names for these arteries are: proper volar digital arteries, collateral digital arteries, arteriae digitales palmares propriae, or aa. digitales volares propriae. They anastomose freely in the subcutaneous tissue of the finger tips and by smaller branches near the interphalangeal joints. Each also gives off a couple of dorsal branches which anastomose with the dorsal digital arteries, and supply the soft parts on the back of the second and third phalanges, including the matrix of the fingernail. The proper palmar digital artery for the medial side of the little finger arises directly from the ulnar artery deep to the palmaris brevis muscle, but the rest arise from the common palmar digital arteries." [Wikipedia:Proper_palmar_digital_arteries] comment: the MA term, even though plural, represents the singular, as it is an isa child of artery synonym: "proper volar digital arteries" RELATED [Wikipedia:Proper_palmar_digital_arteries] synonym: "proper volar digital artery" RELATED [Wikipedia:Proper_palmar_digital_arteries] synonym: "proper palmar digital arteries" EXACT [MA:0001959] synonym: "proper palmal digital arteries" EXACT [MA:0001959] synonym: "proper palmar digital arteries set" EXACT [FMA:70804] xref: MA:0001959 ! proper palmar digital arteries xref: FMA:70804 ! set of proper palmar digital arteries is_a: UBERON:0006141 ! palmar digital artery synonym: "arteriae digitales palmares propriae" EXACT LATIN [FMA:TA, FMA:70804] synonym: "arteriae digitales palmares propriae" RELATED LATIN [Wikipedia:Proper_palmar_digital_arteries] xref: http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray1237.svg xref: SCTID:91778006 ! Entire proper volar digital arteries synonym: "set of proper palmar digital arteries" RELATED [FMA:70804] [Term] id: UBERON:0004554 ! hindlimb digital artery name: hindlimb digital artery def: "A digital artery that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "digital artery of foot" EXACT [FMA:69713] synonym: "hindlimb digital arteries" EXACT [MA:0001964] xref: MA:0001964 ! hindlimb digital arteries xref: FMA:69713 ! Digital artery of foot intersection_of: UBERON:0004552 ! digital artery intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0006138 ! plantar digital artery name: plantar digital artery xref: FMA:43971 ! plantar digital artery is_a: UBERON:0004554 {source="FMA"} ! hindlimb digital artery xref: SCTID:230727008 ! Entire plantar digital artery [Term] id: UBERON:0004540 name: proper plantar digital artery def: "." [Wikipedia:Proper_plantar_digital_arteries] comment: the MA term, even though plural, represents the singular, as it is an isa child of artery. We use the FMA set term as it is the closest match, but the semantics of set terms are unclear synonym: "plantar digital artery proper" EXACT [] synonym: "proper plantar digital arteries" EXACT [MA:0001968] xref: MA:0001968 ! proper plantar digital arteries xref: FMA:71564 ! set of plantar digital arteries proper xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a9/Gray1237.svg/200px-Gray1237.svg.png is_a: UBERON:0006138 ! plantar digital artery synonym: "arteriae digitales plantares propriae" EXACT LATIN [FMA:TA, FMA:71564] synonym: "arteriae digitales plantares propriae" RELATED LATIN [Wikipedia:Proper_plantar_digital_arteries] xref: http://upload.wikimedia.org/wikipedia/commons/3/3e/Gray555.png synonym: "set of plantar digital arteries proper" RELATED [FMA:71564] [Term] id: UBERON:0002455 name: common plantar digital arteries def: "." [Wikipedia:Common_plantar_digital_arteries] synonym: "common plantar digital arteries" EXACT [] synonym: "common plantar digital arteries set" EXACT [FMA:70821] xref: FMA:70821 ! Set of common plantar digital arteries xref: MA:0001966 ! common plantar digital arteries xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3e/Gray555.png/200px-Gray555.png is_a: UBERON:0006138 ! plantar digital artery relationship: has_part UBERON:0001410 ! common palmar digital artery synonym: "arteriae digitales plantares communes" EXACT LATIN [FMA:TA, FMA:70821] synonym: "arteriae digitales plantares communes" RELATED LATIN [Wikipedia:Common_plantar_digital_arteries] xref: http://upload.wikimedia.org/wikipedia/commons/3/3e/Gray555.png synonym: "set of common plantar digital arteries" RELATED [FMA:70821] [Term] id: UBERON:0004551 name: obsolete set of proper plantar digital arteries comment: this class was made obsolete, as uberon does not include 'Set of X' classes. For now, the FMA class for set of plantar digital arteries proper is under UBERON:0004540, but it is unclear if this is correct synonym: "plantar digital arteries proper" EXACT [FMA:71564] synonym: "plantar digital arteries proper set" EXACT [FMA:71564] consider: FMA:71564 ! Set of plantar digital arteries proper is_obsolete: true synonym: "arteriae digitales plantares propriae" EXACT LATIN [FMA:TA, FMA:71564] [Term] id: UBERON:0004562 ! digital vein name: digital vein comment: check part_of - do we need term for digit + metacarpal/tarsal bones? xref: MA:0002101 ! digital vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0002470 ! autopod region xref: ncithesaurus:Digital_Vein ! Digital Vein xref: UMLS:C0447128 [Term] id: UBERON:0004563 ! forelimb digital vein name: forelimb digital vein synonym: "wing digital vein" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "forelimb digital veins" EXACT [MA:0002120] xref: MA:0002120 ! forelimb digital veins intersection_of: UBERON:0004562 ! digital vein intersection_of: part_of UBERON:0002102 ! forelimb def: "A digital vein that is part of a forelimb." [OBOL:automatic] relationship: part_of UBERON:0002398 {is_inferred="true", source="reference_0000032"} ! manus [Term] id: UBERON:0006140 name: palmar digital vein def: "The palmar digital veins (or volar digital veins) on each finger are connected to the dorsal digital veins by oblique intercapitular veins. Some sources distinguish between the \"proper palmar digital veins\", which are more distal, and the \"common palmar digital veins\", which are more proximal." [Wikipedia:Palmar_digital_veins] synonym: "palmar digital veins" EXACT PLURAL [FMA:70895] synonym: "palmar digital veins set" EXACT PLURAL [FMA:70895] synonym: "volar digital veins" RELATED [Wikipedia:Palmar_digital_veins] xref: FMA:70895 ! set of palmar digital veins xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Gray574.png/200px-Gray574.png is_a: UBERON:0004563 ! forelimb digital vein synonym: "venae digitales palmares" EXACT LATIN [FMA:TA, FMA:70895] xref: SCTID:83229009 ! Entire digital palmar vein synonym: "venae digitales palmares" RELATED LATIN [Wikipedia:Palmar_digital_veins] xref: http://upload.wikimedia.org/wikipedia/commons/b/ba/Gray574.png synonym: "set of palmar digital veins" RELATED [FMA:70895] [Term] id: UBERON:0001412 name: common palmar digital vein comment: Some sources distinguish between the "proper palmar digital veins", which are more distal, and the "common palmar digital veins", which are more proximal. synonym: "proximal palmar digital vein" EXACT [Wikipedia:Palmar_digital_veins] xref: FMA:22923 ! Common palmar digital vein xref: MA:0002121 ! common palmar digital vein is_a: UBERON:0004563 ! forelimb digital vein [Term] id: UBERON:0004561 name: proper palmar digital vein comment: Some sources distinguish between the "proper palmar digital veins", which are more distal, and the "common palmar digital veins", which are more proximal. synonym: "distal palmar digital vein" EXACT [Wikipedia:Palmar_digital_veins] synonym: "proper palmar vein" EXACT [MA:0002126] synonym: "proper palmal vein" EXACT [MA:0002126] synonym: "tributary of common palmar digital vein" EXACT [FMA:22926] synonym: "common palmar digital venous tributary" EXACT [FMA:22926] xref: FMA:22926 ! Tributary of common palmar digital vein xref: MA:0002126 ! proper palmar vein xref: MA:0002126 ! proper palmar vein is_a: UBERON:0004563 ! forelimb digital vein relationship: tributary_of UBERON:0001412 {source="FMA/obol"} ! common palmar digital vein [Term] id: UBERON:0004564 ! hindlimb digital vein name: hindlimb digital vein def: "A digital vein that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hindlimb digital veins" EXACT [MA:0002133] xref: MA:0002133 ! hindlimb digital veins intersection_of: UBERON:0004562 ! digital vein intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002387 {is_inferred="true", source="reference_0000032"} ! pes [Term] id: UBERON:0006139 ! plantar digital vein name: plantar digital vein def: "The plantar digital veins arise from plexuses on the plantar surfaces of the digits, and, after sending intercapitular veins to join the dorsal digital veins, unite to form four metatarsal veins." [Wikipedia:Plantar_digital_veins] xref: FMA:44517 ! plantar digital vein is_a: UBERON:0004564 ! hindlimb digital vein synonym: "venae digitales plantares" RELATED LATIN [Wikipedia:Plantar_digital_veins] [Term] id: UBERON:0006142 name: common plantar digital vein synonym: "common plantar vein" EXACT [MA:0002134] xref: MA:0002134 ! common plantar vein is_a: UBERON:0006139 ! plantar digital vein [Term] id: UBERON:0006143 name: proper plantar digital vein synonym: "proper plantar vein" EXACT [MA:0002138] xref: MA:0002138 ! proper plantar vein is_a: UBERON:0006139 ! plantar digital vein [Term] id: UBERON:0006144 name: medial plantar digital vein synonym: "medial plantar vein" EXACT [MA:0002172] xref: MA:0002172 ! medial plantar vein is_a: UBERON:0006139 ! plantar digital vein [Term] id: UBERON:0004572 ! arterial system name: arterial system def: "The part of the cardiovascular system consisting of all arteries." [UBERON:cjm] xref: MA:0002719 ! arterial system xref: VHOG:0000273 ! arterial system xref: EHDAA2:0000143 ! arterial system (also: UBERON:0001637 'artery') xref: BTO:0004690 ! arterial system xref: EMAPA:16201 ! arterial system of cardiovascular system of organ system xref: EMAPA:16371 ! arterial system of cardiovascular system of extraembryonic component xref: EHDAA:396 ! arterial system of cardiovascular system is_a: UBERON:0007798 {source="MA"} ! vascular system relationship: part_of UBERON:0004535 {source="EHDAA2"} ! cardiovascular system xref: SCTID:362030008 ! Entire arterial system property_value: homology_notes "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {external_class="VHOG:0000273", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH\, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004571 ! systemic arterial system name: systemic arterial system def: "the part of the cardiovascular system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart." [Wikipedia:Systemic_circulation#Arteries] synonym: "systemic arterial circulatory system" EXACT [FMA:45623] xref: FMA:45623 ! Systemic arterial system is_a: UBERON:0007798 {source="MA-inferred"} ! vascular system relationship: part_of UBERON:0004572 ! arterial system [Term] id: UBERON:0002012 name: pulmonary artery def: "The pulmonary arteries carry blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood. In the human heart, the pulmonary trunk (pulmonary artery or main pulmonary artery) begins at the base of the right ventricle. It is short and wide - approximately 5 cm (2 inches) in length and 3 cm (1.2 inches) in diameter. It then branches into two pulmonary arteries (left and right), which deliver deoxygenated blood to the corresponding lung. [WP,unvetted]." [Wikipedia:Pulmonary_artery] subset: uberon_slim synonym: "pulmonary arterial tree" EXACT [] synonym: "pulmonary arterial tree organ part" EXACT [] xref: BTO:0000778 xref: EHDAA:4351 ! pulmonary artery xref: FMA:66326 ! Pulmonary artery xref: GAID:505 ! pulmonary artery xref: VHOG:0000982 ! pulmonary artery xref: MA:0002031 ! pulmonary artery xref: OpenCyc:Mx4rvVjbIpwpEbGdrcN5Y29ycA xref: ncithesaurus:Pulmonary_Artery ! Pulmonary Artery xref: EFO:0001399 ! pulmonary artery (also: UBERON:0002333 'pulmonary trunk') xref: galen:PulmonaryArtery ! pulmonary artery xref: OpenCyc:Mx4rvVjbIpwpEbGdrcN5Y29ycA ! pulmonary artery xref: EHDAA2:0001575 ! pulmonary artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Alveoli_diagram.png/200px-Alveoli_diagram.png xref: EMAPA:17008 ! pulmonary artery xref: MESH:A07.231.114.715 ! pulmonary artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0008886 ! pulmonary vascular system relationship: develops_from UBERON:0002061 {source="Wikipedia"} ! truncus arteriosus xref: AAO:0010221 ! pulmonary artery xref: SCTID:181380003 ! Entire pulmonary artery xref: XAO:0004162 ! pulmonary artery synonym: "truncus pulmonalis, arteria pulmonalis" RELATED LATIN [Wikipedia:Pulmonary_artery] property_value: external_definition "Major artery which supplies blood to the lungs.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010221", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "One of two arteries, leaving from the heart, the left one supplying the left lung and the right one supplying the right lung. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000982", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/pulmonary+artery", source="http://bgee.unil.ch/"} property_value: homology_notes "On the other hand, in the sister clade of the actinopterygians, the sarcopterygians, the gill circulation is supplemented with lung ventilation. As a result, the pulmonary artery and vein and a functional ductus arteriosus arose as a major evolutionary innovation from the sixth arch, giving the organism a flexible shunt to balance blood supply to and from gills and lungs according to environmental conditions.[well established][VHOG]" xsd:string {external_class="VHOG:0000982", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0034052 [Term] id: UBERON:0008886 ! pulmonary vascular system name: pulmonary vascular system def: "The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins." [ISBN10:0073040584, Wikipedia:Pulmonary_circulation] synonym: "pulmonary system" EXACT [ISBN10:0073040584] synonym: "pulmonary circulatory system" EXACT [FMA:45621] is_a: UBERON:0007798 {source="Obol"} ! vascular system relationship: part_of UBERON:0004535 {source="FMA"} ! cardiovascular system xref: FMA:45621 ! pulmonary vascular system property_value: external_definition "Subdivision of cardiovascular system which has as its parts the pulmonary arterial and venous tree organs.[FMA]" xsd:string {ontology="FMA", source="FMA:45621"} [Term] id: UBERON:0004573 name: systemic artery def: "Systemic arteries are the arteries of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart." [Wikipedia:Artery#Systemic_arteries] synonym: "systemic arterial subtree" EXACT [FMA:66464] xref: FMA:66464 ! Systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0004571 ! systemic arterial system [Term] id: UBERON:0013140 name: systemic vein synonym: "systemic venous tree organ part" EXACT [FMA:66644] intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0004581 ! systemic venous system xref: FMA:66644 ! systemic vein xref: SCTID:244389004 ! Entire systemic vein xref: ncithesaurus:Systemic_Vein ! systemic vein xref: UMLS:C0447117 [Term] id: UBERON:0004581 name: systemic venous system def: "The part of the venous system that drains the general body tissues[Kardong]" [ISBN10:0073040584, Wikipedia:Systemic_venous_system] synonym: "systemic venous circulatory system" EXACT [FMA:45626] xref: FMA:45626 ! Systemic venous system is_a: UBERON:0002049 ! vasculature relationship: part_of UBERON:0004582 ! venous system property_value: homology_notes "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {external_class="VHOG:0000277", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH\, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: external_definition "Subdivision of cardiovascular system which has as its parts the right side of heart, the superior vena cava and the inferior vena cava[FMA]" xsd:string {ontology="FMA", source="FMA:45626"} property_value: external_definition "In human anatomy, the systemic venous system refers to veins that drain into the right atrium without passing through two vascular beds (i.e. they originate from a set of capillaries and do not pass through a second set of capillaries before reaching the right side of the heart). The term systemic venous system is often used to differentiate veins from veins that drain the pulmonary system (the pulmonary venous system) and veins that drain the digestive tract (the portal venous system). Large veins that are considered part of the systemic venous system are the: Superior vena cava; Inferior vena cava[WP]]" xsd:string {source="Wikipedia:Systemic_venous_system"} [Term] id: UBERON:0013127 name: pulmonary venous system def: "The part of the venous system that drains the lungs[Kardong]" [ISBN10:0073040584, Wikipedia:Pulmonary_venous_system] synonym: "pulmonary venous circulatory system" EXACT [] is_a: UBERON:0002049 ! vasculature relationship: part_of UBERON:0004582 ! venous system relationship: channels_from UBERON:0000102 ! lung vasculature property_value: external_definition "Pulmonary circulation is the half portion of the cardiovascular system which carries oxygen-depleted blood away from the heart, to the lungs, and returns oxygenated (oxygen-rich) blood back to the heart. The term pulmonary circulation is readily paired and contrasted with the systemic circulation. A separate system known as the bronchial circulation supplies blood to the tissue of the larger airways of the lung." xsd:string {source="Wikipedia:Pulmonary_circulation"} [Term] id: UBERON:0004582 ! venous system name: venous system def: "The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions." [UBERON:cjm] synonym: "vein system" EXACT [] xref: MA:0002720 ! venous system xref: VHOG:0000277 ! venous system xref: EHDAA2:0002171 ! venous system xref: EMAPA:16240 ! venous system of cardiovascular system of organ system xref: BTO:0004692 ! venous system xref: EHDAA:486 ! venous system of cardiovascular system is_a: UBERON:0007798 {source="MA"} ! vascular system relationship: composed_primarily_of UBERON:0001638 ! vein xref: ncithesaurus:Venous_System ! Venous System xref: SCTID:362060003 ! Entire venous system property_value: homology_notes "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {external_class="VHOG:0000277", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH\, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1267406 [Term] id: UBERON:0013146 name: venous system of brain def: "." [PMID:20557782, PMID:20566102] synonym: "cranial venous system" RELATED [] synonym: "brain venous system" EXACT [VHOG:0001328] is_a: UBERON:0007798 {source="cjm"} ! vascular system relationship: part_of UBERON:0000955 {source="EHDAA2"} ! brain relationship: part_of UBERON:0004582 {source="VHOG-modified"} ! venous system xref: VHOG:0001328 ! brain venous system xref: EHDAA2:0000185 ! brain venous system xref: EMAPA:18631 ! brain of venous system of cardiovascular system of organ system [Term] id: UBERON:0004590 ! sphincter muscle name: sphincter muscle def: "a structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [Wikipedia:Sphincter] comment: AO notes: FMA class is not a subtype of muscle synonym: "sphincter" EXACT [] synonym: "circular muscle" RELATED [] xref: FMA:75004 ! Sphincter muscle is_a: UBERON:0001630 ! muscle organ xref: ncithesaurus:Sphincter ! Sphincter xref: UMLS:C1409894 [Term] id: UBERON:0007521 ! smooth muscle sphincter name: smooth muscle sphincter def: "A ring of smooth muscle cells whose contraction closes the opening of the ring." [AEO:JB] xref: EHDAA2:0003143 xref: AEO:0000143 ! smooth muscle sphincter is_a: UBERON:0001135 {source="AEO"} ! smooth muscle tissue intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: has_part CL:0000192 ! smooth muscle cell xref: SCTID:362915001 ! Entire smooth muscle sphincter [Term] id: UBERON:0007522 ! striated muscle sphincter name: striated muscle sphincter def: "A ring of striated muscle cells whose contraction closes the opening of the ring." [AEO:JB] xref: EHDAA2:0003144 xref: AEO:0000144 ! striated muscle sphincter is_a: UBERON:0002036 {source="AEO"} ! striated muscle tissue intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: has_part CL:0000737 ! striated muscle cell [Term] id: UBERON:0004601 name: rib 1 def: "The first rib is the most curved and usually the shortest of all the ribs; it is broad and flat, its surfaces looking upward and downward, and its borders inward and outward. The head is small, rounded, and possesses only a single articular facet, for articulation with the body of the first thoracic vertebra. The neck is narrow and rounded. The tubercle, thick and prominent, is placed on the outer border. There is no angle, but at the tubercle the rib is slightly bent, with the convexity upward, so that the head of the bone is directed downward. The upper surface of the body is marked by two shallow grooves, separated from each other by a slight ridge prolonged internally into a tubercle, the scalene tubercle, for the attachment of the Scalenus anterior; the anterior groove transmits the subclavian vein, the posterior the subclavian artery and the lowest trunk of the brachial plexus. Behind the posterior groove is a rough area for the attachment of the Scalenus medius. The under surface is smooth, and destitute of a costal groove. The outer border is convex, thick, and rounded, and at its posterior part gives attachment to the first digitation of the Serratus anterior. The inner border is concave, thin, and sharp, and marked about its center by the scalene tubercle. The anterior extremity is larger and thicker than that of any of the other ribs. [WP,unvetted]." [Wikipedia:First_rib] comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Costa prima (I)" EXACT [FMA:7597] synonym: "first rib" EXACT [FMA:7597] xref: FMA:7597 ! First rib xref: MA:0001401 ! rib 1 xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fa/Gray124.png/200px-Gray124.png is_a: UBERON:0002228 ! rib xref: ncithesaurus:Rib_1 ! Rib 1 xref: SCTID:182016005 ! Entire first rib property_value: rib_number "1" xsd:nonNegativeInteger synonym: "costa prima" RELATED LATIN [Wikipedia:First_rib] xref: http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray124.png xref: UMLS:C1709945 [Term] id: UBERON:0004602 name: rib 2 def: "The second rib is much longer than the first, but has a very similar curvature. The non-articular portion of the tubercle is occasionally only feebly marked. The angle is slight, and situated close to the tubercle. The body is not twisted, so that both ends touch any plane surface upon which it may be laid; but there is a bend, with its convexity upward, similar to, though smaller than that found in the first rib. The body is not flattened horizontally like that of the first rib. Its external surface is convex, and looks upward and a little outward; near the middle of it is a rough eminence for the origin of the lower part of the first and the whole of the second digitation of the Serratus anterior; behind and above this is attached the Scalenus posterior. The internal surface, smooth, and concave, is directed downward and a little inward: on its posterior part there is a short costal groove. [WP,unvetted]." [Wikipedia:Second_rib] comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Costa secunda (II)" EXACT [FMA:7620] synonym: "second rib" EXACT [FMA:7620] xref: FMA:7620 ! Second rib xref: MA:0001402 ! rib 2 xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Gray125.png/200px-Gray125.png is_a: UBERON:0002228 ! rib xref: ncithesaurus:Rib_2 ! Rib 2 xref: SCTID:244656007 ! Entire second rib property_value: rib_number "2" xsd:nonNegativeInteger synonym: "costa secunda" RELATED LATIN [Wikipedia:Second_rib] xref: http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray125.png xref: UMLS:C1709949 [Term] id: UBERON:0004603 name: rib 3 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "third rib" EXACT [FMA:7638] xref: FMA:7638 ! Third rib xref: MA:0001403 ! rib 3 is_a: UBERON:0002228 ! rib xref: ncithesaurus:Rib_3 ! Rib 3 xref: SCTID:244658008 ! Entire third rib property_value: rib_number "3" xsd:nonNegativeInteger xref: UMLS:C1709950 [Term] id: UBERON:0004604 name: rib 4 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "fourth rib" EXACT [FMA:7749] xref: FMA:7749 ! Fourth rib xref: MA:0001404 ! rib 4 is_a: UBERON:0002228 ! rib xref: ncithesaurus:Rib_4 ! Rib 4 xref: SCTID:244659000 ! Entire fourth rib property_value: rib_number "4" xsd:nonNegativeInteger xref: UMLS:C1709951 [Term] id: UBERON:0004605 name: rib 5 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "fifth rib" EXACT [FMA:7776] xref: FMA:7776 ! Fifth rib xref: MA:0001405 ! rib 5 is_a: UBERON:0002228 ! rib xref: ncithesaurus:Rib_5 ! Rib 5 xref: SCTID:244660005 ! Entire fifth rib property_value: rib_number "5" xsd:nonNegativeInteger xref: UMLS:C1711376 [Term] id: UBERON:0004606 name: rib 6 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "sixth rib" EXACT [FMA:8147] xref: FMA:8147 ! Sixth rib xref: MA:0001406 ! rib 6 is_a: UBERON:0002228 ! rib xref: ncithesaurus:Rib_6 ! Rib 6 xref: SCTID:244661009 ! Entire sixth rib property_value: rib_number "6" xsd:nonNegativeInteger xref: UMLS:C1709952 [Term] id: UBERON:0004607 name: rib 7 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "seventh rib" EXACT [FMA:7830] xref: FMA:7830 ! Seventh rib xref: MA:0001407 ! rib 7 is_a: UBERON:0002228 ! rib xref: ncithesaurus:Rib_7 ! Rib 7 xref: SCTID:244662002 ! Entire seventh rib property_value: rib_number "7" xsd:nonNegativeInteger xref: UMLS:C1709953 [Term] id: UBERON:0010757 name: rib 8 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series is_a: UBERON:0002228 ! rib is_a: UBERON:0002238 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! false rib xref: MA:0001408 ! rib 8 xref: ncithesaurus:Rib_8 ! rib 8 xref: SCTID:244663007 ! Entire eighth rib xref: FMA:8120 ! eighth rib property_value: rib_number "8" xsd:nonNegativeInteger synonym: "eighth rib" EXACT [FMA:8120] xref: UMLS:C1709954 [Term] id: UBERON:0004608 name: rib 9 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "ninth rib" EXACT [FMA:8337] xref: FMA:8337 ! Ninth rib xref: MA:0001409 ! rib 9 is_a: UBERON:0002228 ! rib is_a: UBERON:0002238 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! false rib xref: ncithesaurus:Rib_9 ! Rib 9 xref: SCTID:244664001 ! Entire ninth rib property_value: rib_number "9" xsd:nonNegativeInteger xref: UMLS:C1709955 [Term] id: UBERON:0004609 name: rib 10 def: "The tenth rib has only a single articular facet on its head. [WP,unvetted]." [Wikipedia:Tenth_rib] comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "tenth rib" EXACT [FMA:8418] xref: FMA:8418 ! Tenth rib xref: MA:0001410 ! rib 10 xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Gray126.png/200px-Gray126.png is_a: UBERON:0002228 ! rib is_a: UBERON:0002238 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! false rib xref: ncithesaurus:Rib_10 ! Rib 10 xref: SCTID:244665000 ! Entire tenth rib property_value: rib_number "10" xsd:nonNegativeInteger xref: http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray126.png xref: UMLS:C1709946 [Term] id: UBERON:0004610 name: rib 11 def: "The eleventh rib has a single articular facet on the head, which is of rather large size. It has no necks or tubercles, and is pointed at its anterior ends. The eleventh has a slight angle and a shallow costal groove. [WP,unvetted]." [Wikipedia:Eleventh_rib] comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "eleventh rib" EXACT [FMA:8499] xref: FMA:8499 ! Eleventh rib xref: MA:0001411 ! rib 11 is_a: UBERON:0002228 ! rib is_a: UBERON:0002239 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! floating rib xref: ncithesaurus:Rib_11 ! Rib 11 xref: SCTID:244666004 ! Entire eleventh rib property_value: rib_number "11" xsd:nonNegativeInteger xref: http://upload.wikimedia.org/wikipedia/commons/d/db/Gray127.png xref: UMLS:C1709947 [Term] id: UBERON:0004611 name: rib 12 def: "In humans: The twelfth rib has a single articular facet on the head, which is of rather large size. It has no necks or tubercles, and is pointed at its anterior ends. The twelfth has angle nor costal groove; it is much shorter than the eleventh rib, and its head is inclined slightly downward. Sometimes the twelfth rib is even shorter than the first rib. [WP,unvetted]." [Wikipedia:Twelfth_rib] comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "twelfth rib" EXACT [FMA:8515] xref: FMA:8515 ! Twelfth rib xref: MA:0001412 ! rib 12 xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Gray128.png/200px-Gray128.png is_a: UBERON:0002228 ! rib is_a: UBERON:0002239 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! floating rib xref: ncithesaurus:Rib_12 ! Rib 12 xref: SCTID:244667008 ! Entire twelfth rib property_value: rib_number "12" xsd:nonNegativeInteger xref: http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray128.png xref: UMLS:C1709948 [Term] id: UBERON:0004612 name: mammalian cervical vertebra 3 comment: elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae subset: defined_by_ordinal_series synonym: "C3 vertebra" EXACT [FMA:12521] synonym: "third cervical vertebra" EXACT [FMA:12521] xref: FMA:12521 ! Third cervical vertebra xref: MA:0001423 ! cervical vertebra 3 synonym: "cervical vertebra 3" EXACT [MA:0001423] xref: EMAPA:19433 ! C3 of vertebra of cervical region is_a: UBERON:0002413 ! cervical vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:C3_Vertebra ! C3 Vertebra xref: SCTID:181823007 ! Entire C3 vertebra property_value: vertebra_number "3" xsd:nonNegativeInteger relationship: anteriorly_connected_to UBERON:0001093 {source="FMA"} ! cervical vertebra 2 xref: UMLS:C0459939 [Term] id: UBERON:0004613 name: mammalian cervical vertebra 4 comment: elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae subset: defined_by_ordinal_series synonym: "C4 vertebra" EXACT [FMA:12522] synonym: "fourth cervical vertebra" EXACT [FMA:12522] xref: FMA:12522 ! Fourth cervical vertebra xref: MA:0001424 ! cervical vertebra 4 synonym: "cervical vertebra 4" EXACT [MA:0001424] xref: EMAPA:19434 ! C4 of vertebra of cervical region is_a: UBERON:0002413 ! cervical vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:C4_Vertebra ! C4 Vertebra xref: SCTID:181824001 ! Entire C4 vertebra property_value: vertebra_number "4" xsd:nonNegativeInteger relationship: anteriorly_connected_to UBERON:0004612 {source="FMA"} ! mammalian cervical vertebra 3 xref: UMLS:C0459941 [Term] id: UBERON:0004614 name: mammalian cervical vertebra 5 comment: elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae subset: defined_by_ordinal_series synonym: "C5 vertebra" EXACT [FMA:12523] synonym: "fifth cervical vertebra" EXACT [FMA:12523] xref: FMA:12523 ! Fifth cervical vertebra xref: MA:0001425 ! cervical vertebra 5 xref: EMAPA:19435 ! C5 of vertebra of cervical region is_a: UBERON:0002413 ! cervical vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:C5_Vertebra ! C5 Vertebra xref: SCTID:181825000 ! Entire C5 vertebra property_value: vertebra_number "5" xsd:nonNegativeInteger relationship: anteriorly_connected_to UBERON:0004613 {source="FMA"} ! mammalian cervical vertebra 4 synonym: "cervical vertebra 5" EXACT [MA:0001425] xref: UMLS:C0459943 [Term] id: UBERON:0004615 name: mammalian cervical vertebra 6 comment: elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae subset: defined_by_ordinal_series synonym: "C6 vertebra" EXACT [FMA:12524] synonym: "sixth cervical vertebra" EXACT [FMA:12524] synonym: "cervical vertebra 6" EXACT [MA:0001426] xref: FMA:12524 ! Sixth cervical vertebra xref: MA:0001426 ! cervical vertebra 6 xref: EMAPA:19466 ! C6 of vertebra of cervical region is_a: UBERON:0002413 ! cervical vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:C6_Vertebra ! C6 Vertebra xref: SCTID:181826004 ! Entire C6 vertebra property_value: vertebra_number "6" xsd:nonNegativeInteger relationship: anteriorly_connected_to UBERON:0004614 {source="FMA"} ! mammalian cervical vertebra 5 xref: UMLS:C0459944 [Term] id: UBERON:0004616 name: mammalian cervical vertebra 7 comment: elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae subset: defined_by_ordinal_series synonym: "C7 vertebra" EXACT [FMA:12525] synonym: "prominent vertebra" EXACT [FMA:12525] synonym: "vertebra prominens (CVII)" EXACT [FMA:12525] synonym: "seventh cervical vertebra" EXACT [FMA:12525] xref: FMA:12525 ! Seventh cervical vertebra xref: MA:0001427 ! cervical vertebra 7 synonym: "cervical vertebra 7" EXACT [MA:0001427] xref: EMAPA:19467 ! C7 of vertebra of cervical region is_a: UBERON:0002413 ! cervical vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:C7_Vertebra ! C7 Vertebra xref: SCTID:181827008 ! Entire C7 vertebra property_value: vertebra_number "7" xsd:nonNegativeInteger relationship: anteriorly_connected_to UBERON:0004615 {source="FMA"} ! mammalian cervical vertebra 6 xref: UMLS:C0223176 [Term] id: UBERON:0004617 name: lumbar vertebra 1 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "L1 vertebra" EXACT [FMA:13072] synonym: "first lumbar vertebra" EXACT [FMA:13072] xref: FMA:13072 ! First lumbar vertebra xref: MA:0001428 ! lumbar vertebra 1 xref: EMAPA:19472 ! L1 of vertebra of lumbar region is_a: UBERON:0002414 ! lumbar vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:L1_Vertebra ! L1 Vertebra xref: SCTID:181841004 ! Entire L1 vertebra relationship: anteriorly_connected_to UBERON:0004636 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! thoracic vertebra 12 xref: UMLS:C0223492 [Term] id: UBERON:0004618 name: lumbar vertebra 2 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "L2 vertebra" EXACT [FMA:13073] synonym: "second lumbar vertebra" EXACT [FMA:13073] xref: FMA:13073 ! Second lumbar vertebra xref: MA:0001429 ! lumbar vertebra 2 xref: EMAPA:19570 ! L2 of vertebra of lumbar region is_a: UBERON:0002414 ! lumbar vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:L2_Vertebra ! L2 Vertebra xref: SCTID:181842006 ! Entire L2 vertebra relationship: anteriorly_connected_to UBERON:0004617 {source="FMA"} ! lumbar vertebra 1 xref: UMLS:C0223507 [Term] id: UBERON:0004619 name: lumbar vertebra 3 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "L3 vertebra" EXACT [FMA:13074] synonym: "third lumbar vertebra" EXACT [FMA:13074] xref: FMA:13074 ! Third lumbar vertebra xref: MA:0001430 ! lumbar vertebra 3 xref: EMAPA:19571 ! L3 of vertebra of lumbar region is_a: UBERON:0002414 ! lumbar vertebra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: ncithesaurus:L3_Vertebra ! L3 Vertebra xref: SCTID:181843001 ! Entire L3 vertebra relationship: anteriorly_connected_to UBERON:0004618 {source="FMA"} ! lumbar vertebra 2 xref: UMLS:C0223522 [Term] id: UBERON:0004620 name: lumbar vertebra 4 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "L4 vertebra" EXACT [FMA:13075] synonym: "fourth lumbar vertebra" EXACT [FMA:13075] xref: FMA:13075 ! Fourth lumbar vertebra xref: MA:0001431 ! lumbar vertebra 4 xref: EMAPA:19572 ! L4 of vertebra of lumbar region is_a: UBERON:0002414 ! lumbar vertebra xref: ncithesaurus:L4_Vertebra ! L4 Vertebra xref: SCTID:181844007 ! Entire L4 vertebra relationship: anteriorly_connected_to UBERON:0004619 {source="FMA"} ! lumbar vertebra 3 xref: UMLS:C0223537 [Term] id: UBERON:0004621 name: lumbar vertebra 5 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "L5 vertebra" EXACT [FMA:13076] synonym: "fifth lumbar vertebra" EXACT [FMA:13076] xref: FMA:13076 ! Fifth lumbar vertebra xref: MA:0001432 ! lumbar vertebra 5 xref: EMAPA:19573 ! L5 of vertebra of lumbar region is_a: UBERON:0002414 ! lumbar vertebra xref: ncithesaurus:L5_Vertebra ! L5 Vertebra xref: SCTID:181845008 ! Entire L5 vertebra relationship: anteriorly_connected_to UBERON:0004620 {source="FMA"} ! lumbar vertebra 4 xref: UMLS:C0223552 [Term] id: UBERON:0004622 name: sacral vertebra 1 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "First sacral segment" EXACT [FMA:13077] synonym: "First segment of sacrum" EXACT [FMA:13077] synonym: "S1 vertebra" EXACT [FMA:13077] synonym: "first sacral vertebra" EXACT [FMA:13077] xref: FMA:13077 ! First sacral vertebra xref: MA:0001434 ! sacral vertebra 1 is_a: UBERON:0001094 ! sacral vertebra xref: ncithesaurus:S1_Vertebra ! S1 Vertebra xref: SCTID:181846009 ! Entire first sacral vertebra xref: EMAPA:19588 ! S1 of vertebra of sacral region xref: UMLS:C0223598 [Term] id: UBERON:0004623 name: sacral vertebra 2 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "S2 vertebra" EXACT [FMA:13078] synonym: "Second sacral segment" EXACT [FMA:13078] synonym: "Second segment of sacrum" EXACT [FMA:13078] synonym: "second sacral vertebra" EXACT [FMA:13078] xref: FMA:13078 ! Second sacral vertebra xref: MA:0001435 ! sacral vertebra 2 is_a: UBERON:0001094 ! sacral vertebra xref: ncithesaurus:S2_Vertebra ! S2 Vertebra xref: SCTID:181847000 ! Entire second sacral vertebra xref: EMAPA:19589 ! S2 of vertebra of sacral region xref: UMLS:C0223599 [Term] id: UBERON:0004624 name: sacral vertebra 3 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "S3 vertebra" EXACT [FMA:13079] synonym: "Third sacral segment" EXACT [FMA:13079] synonym: "Third segment of sacrum" EXACT [FMA:13079] synonym: "third sacral vertebra" EXACT [FMA:13079] xref: FMA:13079 ! Third sacral vertebra xref: MA:0001436 ! sacral vertebra 3 xref: EMAPA:19590 ! S3 of vertebra of sacral region is_a: UBERON:0001094 ! sacral vertebra xref: ncithesaurus:S3_Vertebra ! S3 Vertebra xref: SCTID:181848005 ! Entire third sacral vertebra xref: UMLS:C0223600 [Term] id: UBERON:0004625 name: sacral vertebra 4 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Fourth sacral segment" EXACT [FMA:13080] synonym: "Fourth segment of sacrum" EXACT [FMA:13080] synonym: "S4 vertebra" EXACT [FMA:13080] synonym: "fourth sacral vertebra" EXACT [FMA:13080] xref: FMA:13080 ! Fourth sacral vertebra xref: MA:0001437 ! sacral vertebra 4 xref: EMAPA:19591 ! S4 of vertebra of sacral region is_a: UBERON:0001094 ! sacral vertebra xref: ncithesaurus:S4_Vertebra ! S4 Vertebra xref: SCTID:181849002 ! Entire fourth sacral vertebra xref: UMLS:C0223601 [Term] id: UBERON:0004626 name: thoracic vertebra 1 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "First dorsal vertebra" EXACT [FMA:9165] synonym: "T1 vertebra" EXACT [FMA:9165] synonym: "first thoracic vertebra" EXACT [FMA:9165] xref: FMA:9165 ! First thoracic vertebra xref: MA:0001438 ! thoracic vertebra 1 xref: EMAPA:19542 ! T1 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T1_Vertebra ! T1 Vertebra xref: SCTID:181828003 ! Entire T1 vertebra relationship: anteriorly_connected_to UBERON:0004616 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! mammalian cervical vertebra 7 xref: UMLS:C0459933 [Term] id: UBERON:0004627 name: thoracic vertebra 2 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Second dorsal vertebra" EXACT [FMA:9187] synonym: "T2 vertebra" EXACT [FMA:9187] synonym: "second thoracic vertebra" EXACT [FMA:9187] xref: FMA:9187 ! Second thoracic vertebra xref: MA:0001439 ! thoracic vertebra 2 xref: EMAPA:19543 ! T2 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T2_Vertebra ! T2 Vertebra xref: SCTID:181829006 ! Entire T2 vertebra relationship: anteriorly_connected_to UBERON:0004626 {source="FMA"} ! thoracic vertebra 1 xref: UMLS:C0459936 [Term] id: UBERON:0004628 name: thoracic vertebra 3 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "T3 vertebra" EXACT [FMA:9209] synonym: "Third dorsal vertebra" EXACT [FMA:9209] synonym: "third thoracic vertebra" EXACT [FMA:9209] xref: FMA:9209 ! Third thoracic vertebra xref: MA:0001440 ! thoracic vertebra 3 xref: EMAPA:19544 ! T3 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T3_Vertebra ! T3 Vertebra xref: SCTID:181830001 ! Entire T3 vertebra relationship: anteriorly_connected_to UBERON:0004627 {source="FMA"} ! thoracic vertebra 2 xref: UMLS:C0459952 [Term] id: UBERON:0004629 name: thoracic vertebra 4 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Fourth dorsal vertebra" EXACT [FMA:9248] synonym: "T4 vertebra" EXACT [FMA:9248] synonym: "fourth thoracic vertebra" EXACT [FMA:9248] xref: FMA:9248 ! Fourth thoracic vertebra xref: MA:0001441 ! thoracic vertebra 4 xref: EMAPA:19545 ! T4 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T4_Vertebra ! T4 Vertebra xref: SCTID:181831002 ! Entire T4 vertebra relationship: anteriorly_connected_to UBERON:0004628 {source="FMA"} ! thoracic vertebra 3 xref: UMLS:C0459951 [Term] id: UBERON:0004630 name: thoracic vertebra 5 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Fifth dorsal vertebra" EXACT [FMA:9922] synonym: "T5 vertebra" EXACT [FMA:9922] synonym: "fifth thoracic vertebra" EXACT [FMA:9922] xref: FMA:9922 ! Fifth thoracic vertebra xref: MA:0001442 ! thoracic vertebra 5 xref: EMAPA:19546 ! T5 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T5_Vertebra ! T5 Vertebra xref: SCTID:181832009 ! Entire T5 vertebra relationship: anteriorly_connected_to UBERON:0004629 {source="FMA"} ! thoracic vertebra 4 xref: UMLS:C0459950 [Term] id: UBERON:0004631 name: thoracic vertebra 6 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Sixth dorsal vertebra" EXACT [FMA:9945] synonym: "T6 vertebra" EXACT [FMA:9945] synonym: "sixth thoracic vertebra" EXACT [FMA:9945] xref: FMA:9945 ! Sixth thoracic vertebra xref: MA:0001443 ! thoracic vertebra 6 xref: EMAPA:19547 ! T6 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T6_Vertebra ! T6 Vertebra xref: SCTID:181834005 ! Entire T6 vertebra relationship: anteriorly_connected_to UBERON:0004630 {source="FMA"} ! thoracic vertebra 5 xref: UMLS:C0459949 [Term] id: UBERON:0004632 name: thoracic vertebra 7 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Seventh dorsal vertebra" EXACT [FMA:9968] synonym: "T7 vertebra" EXACT [FMA:9968] synonym: "seventh thoracic vertebra" EXACT [FMA:9968] xref: FMA:9968 ! Seventh thoracic vertebra xref: MA:0001444 ! thoracic vertebra 7 xref: EMAPA:19548 ! T7 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T7_Vertebra ! T7 Vertebra xref: SCTID:181835006 ! Entire T7 vertebra relationship: anteriorly_connected_to UBERON:0004631 {source="FMA"} ! thoracic vertebra 6 xref: UMLS:C0459947 [Term] id: UBERON:0011050 ! thoracic vertebra 8 name: thoracic vertebra 8 synonym: "eighth dorsal vertebra" EXACT [FMA:9991] synonym: "T8 vertebra" EXACT [FMA:9991] synonym: "eighth thoracic vertebra" EXACT [FMA:9991] is_a: UBERON:0002347 {source="MA"} ! thoracic vertebra xref: MA:0001445 ! thoracic vertebra 8 xref: FMA:9991 ! eighth thoracic vertebra xref: EMAPA:19549 xref: ncithesaurus:T8_Vertebra ! t8 vertebra xref: SCTID:181836007 ! Entire T8 vertebra relationship: anteriorly_connected_to UBERON:0004632 {source="FMA"} ! thoracic vertebra 7 xref: UMLS:C0459953 [Term] id: UBERON:0004633 name: thoracic vertebra 9 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Ninth dorsal vertebra" EXACT [FMA:10014] synonym: "T9 vertebra" EXACT [FMA:10014] synonym: "ninth thoracic vertebra" EXACT [FMA:10014] xref: FMA:10014 ! Ninth thoracic vertebra xref: MA:0001446 ! thoracic vertebra 9 xref: EMAPA:19550 ! T9 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T9_Vertebra ! T9 Vertebra xref: SCTID:181837003 ! Entire T9 vertebra relationship: anteriorly_connected_to UBERON:0011050 {source="FMA"} ! thoracic vertebra 8 xref: UMLS:C0459954 [Term] id: UBERON:0004634 name: thoracic vertebra 10 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "T10 vertebra" EXACT [FMA:10037] synonym: "Tenth dorsal vertebra" EXACT [FMA:10037] synonym: "tenth thoracic vertebra" EXACT [FMA:10037] xref: FMA:10037 ! Tenth thoracic vertebra xref: MA:0001447 ! thoracic vertebra 10 xref: EMAPA:19551 ! T10 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T10_Vertebra ! T10 Vertebra xref: SCTID:181838008 ! Entire T10 vertebra relationship: anteriorly_connected_to UBERON:0004633 {source="FMA"} ! thoracic vertebra 9 xref: UMLS:C0459955 [Term] id: UBERON:0004635 name: thoracic vertebra 11 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "Eleventh dorsal vertebra" EXACT [FMA:10059] synonym: "T11 vertebra" EXACT [FMA:10059] synonym: "eleventh thoracic vertebra" EXACT [FMA:10059] xref: FMA:10059 ! Eleventh thoracic vertebra xref: MA:0001448 ! thoracic vertebra 11 xref: EMAPA:19552 ! T11 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T11_Vertebra ! T11 Vertebra xref: SCTID:181839000 ! Entire T11 vertebra relationship: anteriorly_connected_to UBERON:0004634 {source="FMA"} ! thoracic vertebra 10 xref: UMLS:C0459956 [Term] id: UBERON:0004636 name: thoracic vertebra 12 comment: elements are to be defined spatially/topologically subset: defined_by_ordinal_series synonym: "T12 vertebra" EXACT [FMA:10081] synonym: "Twelfth dorsal vertebra" EXACT [FMA:10081] synonym: "twelfth thoracic vertebra" EXACT [FMA:10081] xref: FMA:10081 ! Twelfth thoracic vertebra xref: MA:0001449 ! thoracic vertebra 12 xref: EMAPA:19553 ! T12 of vertebra of thoracic region is_a: UBERON:0002347 ! thoracic vertebra xref: ncithesaurus:T12_Vertebra ! T12 Vertebra xref: SCTID:181840003 ! Entire T12 vertebra relationship: anteriorly_connected_to UBERON:0004635 {source="FMA"} ! thoracic vertebra 11 xref: UMLS:C0459957 [Term] id: UBERON:0003915 ! endothelial tube name: endothelial tube def: "Any endothelium that has the quality of being cylindrical [Automatically generated definition]." [OBOL:automatic] is_a: UBERON:0003914 ! epithelial tube intersection_of: UBERON:0001986 ! endothelium intersection_of: has_quality PATO:0001873 ! cylindrical [Term] id: UBERON:0001986 name: endothelium def: "A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]" [MESH:A10.272.491, FMA:63916] comment: The term ‘‘endothelium’’ has been either restricted to the continuous cell layer of the vertebrates, as we are assuming here, or applied to all the cells able to adhere to the luminal surface of the vascular basement membrane (Casley-Smith 1980) subset: uberon_slim xref: BTO:0000393 ! endothelium xref: FMA:63916 ! Endothelium xref: GAID:520 ! endothelium xref: galen:Endothelium xref: ncithesaurus:Endothelium ! Endothelium xref: ncithesaurus:Vascular_Endothelium ! Vascular Endothelium xref: EMAPA:18578 ! endothelium of future tympanic membrane xref: EMAPA:19063 ! endothelium of tympanic membrane primordium xref: MESH:A10.272.491 ! endothelium xref: EFO:0002548 ! endothelium is_a: UBERON:0000487 {source="FMA-text-def"} ! simple squamous epithelium relationship: has_part CL:0000115 {source="FMA"} ! endothelial cell relationship: develops_from UBERON:0000926 {source="FMA-inferred"} ! mesoderm relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata xref: SCTID:27168002 ! Endothelium property_value: has_relational_adjective "endothelial" xsd:string xref: UMLS:C0014257 xref: UMLS:C0014261 [Term] id: UBERON:0004852 name: cardiovascular system endothelium def: "An endothelium that is part of the cardiovascular system." [UBERON:cjm] comment: consider merging with 'endothelium' subset: vertebrate_core xref: MA:0000717 ! cardiovascular system endothelium xref: VHOG:0001217 ! vascular endothelium xref: XAO:0000356 ! vascular endothelium xref: ZFA:0001639 ! vascular endothelium xref: MESH:A07.231.330 ! vascular endothelium xref: BTO:0001853 ! vascular endothelium xref: GAID:519 ! vascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004535 ! cardiovascular system xref: TAO:0002171 ! vascular endothelium property_value: homology_notes "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {external_class="VHOG:0001217", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE\, Fox RS\, Barnes RD\, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004638 name: blood vessel endothelium def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart" [UBERON:cjm] subset: vertebrate_core xref: ZFA:0005257 ! blood vessel endothelium xref: MA:0000709 ! blood vessel endothelium xref: BTO:0000766 ! blood vessel endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel xref: ncithesaurus:Blood_Vessel_Endothelium ! Blood Vessel Endothelium xref: TAO:0005257 ! blood vessel endothelium xref: UMLS:C1706972 [Term] id: UBERON:0004639 name: afferent arteriole def: "The afferent arterioles are a group of blood vessels that supply the nephrons in many excretory systems. They play an important role in the regulation of blood pressure. The afferent arterioles branch from the renal artery which supplies blood to the kidneys. The afferent arterioles later diverge into the capillaries of the glomerulus. When renal blood flow is reduced, the macula densa releases prostaglandins, which cause the juxtaglomerular cells lining the afferent arterioles to release renin, activating the renin-angiotensin-aldosterone system, to increase blood pressure. [WP,unvetted]." [Wikipedia:Afferent_arterioles] subset: vertebrate_core xref: ZFA:0005307 ! afferent glomerular arteriole synonym: "afferent glomerular arteriole" EXACT [ZFA:0005307] xref: MA:0002579 ! afferent arteriole xref: EMAPA:28230 ! afferent arteriole of juxtaglomerular arteriole xref: EMAPA:28266 ! afferent arteriole of mature renal corpuscle is_a: UBERON:0001980 ! arteriole relationship: part_of UBERON:0001229 ! renal corpuscle xref: SCTID:67498004 ! Entire afferent arteriole xref: MP:0011312 ! abnormal kidney afferent arteriole morphology synonym: "kidney afferent arteriole" EXACT [MP:0011312] xref: TAO:0002139 ! afferent arteriole synonym: "arteriola glomerularis afferens" RELATED LATIN [Wikipedia:Afferent_arterioles] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray1128.png [Term] id: UBERON:0004640 name: efferent arteriole def: "The efferent arterioles are blood vessels that are part of the urinary tract of organisms. The efferent arterioles form from a convergence of the capillaries of the glomerulus. They play an important role in maintaining the glomerular filtration rate despite fluctuations in blood pressure. In the mammalian kidney they follow two markedly different courses, depending on the location of the glomeruli from which they arise. In the mammalian kidney about 15% of glomeruli lie close to the boundary between the renal cortex and renal medulla and are known as juxtamedullary glomeruli. The rest are simply undifferentiated cortical glomeruli. [WP,unvetted]." [Wikipedia:Efferent_arteriole] subset: vertebrate_core xref: ZFA:0005308 ! efferent glomerular arteriole synonym: "efferent glomerular arteriole" EXACT [ZFA:0005308] xref: MA:0002585 ! efferent arteriole xref: EMAPA:28233 ! efferent arteriole of juxtaglomerular arteriole xref: EMAPA:28275 ! efferent arteriole of mature renal corpuscle is_a: UBERON:0001980 ! arteriole relationship: part_of UBERON:0001229 ! renal corpuscle relationship: capable_of GO:0003093 {source="Wikipedia"} ! regulation of glomerular filtration xref: SCTID:29926005 ! Entire efferent arteriole synonym: "kidney efferent arteriole" EXACT [MP:0011313] xref: TAO:0002140 ! efferent arteriole synonym: "arteriola glomerularis efferens capsulae renalis" RELATED LATIN [Wikipedia:Efferent_arteriole] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray1128.png [Term] id: UBERON:0004641 name: spleen capsule def: "A capsule that is part of a spleen [Automatically generated definition]." [OBOL:automatic] synonym: "capsule of spleen" EXACT [FMA:15849] synonym: "fibroelastic coat of spleen" EXACT [FMA:15849] synonym: "Malpighian capsule" EXACT [FMA:15849] synonym: "splenic capsule" EXACT [FMA:15849] synonym: "tunica fibrosa (splen)(lien)" EXACT [FMA:15849] synonym: "fibrous capsule of spleen" EXACT [FMA:15849] xref: FMA:15849 ! Fibrous capsule of spleen xref: MA:0000753 ! spleen capsule intersection_of: UBERON:0003893 ! capsule intersection_of: part_of UBERON:0002106 ! spleen xref: ncithesaurus:Splenic_Capsule ! Splenic Capsule xref: SCTID:329635002 ! Entire fibroelastic coat of spleen xref: UMLS:C0229681 [Term] id: UBERON:0004670 ! ependyma name: ependyma def: "the thin epithelial membrane lining the ventricular system of the brain and the spinal cord. Ependyma is one of the four types of neuroglia in the central nervous system. It is involved in the production of cerebrospinal fluid (CSF). It is simple, columnar or cuboidal." [BTO:0000401, Wikipedia:Ependyma] comment: FMA breaks ependyma into epednyma proper (a subdivsion of epithelium) and epithelium of choroid plexus synonym: "ependymal epithelium" EXACT [BTO:0000401] synonym: "lamina epithelialis" RELATED [FMA:242791] synonym: "ependyma of neuraxis" EXACT [FMA:242791] xref: BTO:0000401 ! ependymal epithelium xref: FMA:242791 ! ependyma of neuraxis xref: GAID:608 ! ependyma xref: MESH:A08.186.211.276.460 ! ependyma (also: UBERON:0005357 'brain ependyma') intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005358 ! ventricle of nervous system relationship: composed_primarily_of CL:0000065 ! ependymal cell xref: ncithesaurus:Ependyma ! Ependyma xref: SCTID:12766003 ! Ependyma xref: http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray667.png property_value: has_relational_adjective "ependymal" xsd:string xref: UMLS:C0014472 [Term] id: UBERON:0005357 name: brain ependyma comment: in FMA this is treated as part of the ependyma, but here we treat ependyma as a portion synonym: "ependyma of ventricular system of brain" EXACT [FMA:242837] xref: MA:0000809 ! brain ependyma xref: FMA:242837 ! Ependyma of ventricular system of brain xref: MESH:A08.186.211.276.460 ! ependyma (also: UBERON:0004670 'ependyma') intersection_of: UBERON:0004670 ! ependyma intersection_of: part_of UBERON:0004086 ! brain ventricle def: "An ependyma that is part of a brain ventricle." [OBOL:automatic] [Term] id: UBERON:0005359 name: spinal cord ependyma comment: in FMA this is treated as part of the ependyma, but here we treat ependyma as a portion synonym: "spinal cord ventricular layer" RELATED [] synonym: "spinal cord ependymal layer" EXACT [MA:0001125] synonym: "ependyma of central canal of spinal cord" EXACT [FMA:242839] xref: MA:0001125 ! spinal cord ependymal layer xref: FMA:242839 ! ependyma of central canal of spinal cord xref: EMAPA:17585 ! ventricular layer of lateral wall of spinal cord of central nervous system of nervous system of organ system intersection_of: UBERON:0004670 ! ependyma intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002291 ! central canal xref: SCTID:369278000 ! Entire ependyma of spinal cord def: "An ependyma that is part of a spinal cord." [OBOL:automatic] [Term] id: UBERON:0004642 name: third ventricle ependyma def: "An ependyma that is part of a third ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "3rd ventricle ependyma" EXACT [MA:0000882] synonym: "ependyma of third ventricle" EXACT [MA:0000882] xref: FMA:242833 ! Ependyma of third ventricle xref: MA:0000882 ! third ventricle ependyma intersection_of: UBERON:0004670 ! ependyma intersection_of: part_of UBERON:0002286 ! third ventricle xref: SCTID:362316006 ! Entire ependyma of third ventricle [Term] id: UBERON:0004643 name: lateral ventricle ependyma def: "An ependyma that is part of a lateral ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "ependyma of lateral ventricle" EXACT [FMA:242825] xref: FMA:242825 ! Ependyma of lateral ventricle xref: MA:0000964 ! lateral ventricle ependyma intersection_of: UBERON:0004670 ! ependyma intersection_of: part_of UBERON:0002285 ! telencephalic ventricle xref: ncithesaurus:Lateral_Ventricle_Ependyma ! Lateral Ventricle Ependyma xref: SCTID:369275002 ! Entire ependyma of lateral ventricle xref: UMLS:C0228162 [Term] id: UBERON:0004644 name: fourth ventricle ependyma def: "An ependyma that is part of a fourth ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "4th ventricle ependyma" RELATED [MA:0000986] synonym: "ependyma of fourth ventricle" EXACT [FMA:242835] xref: FMA:242835 ! Ependyma of fourth ventricle xref: MA:0000986 ! fourth ventricle ependyma intersection_of: UBERON:0004670 ! ependyma intersection_of: part_of UBERON:0002422 ! fourth ventricle xref: ncithesaurus:Fourth_Ventricle_Ependyma ! Fourth Ventricle Ependyma xref: SCTID:369277005 ! Entire ependyma of fourth ventricle xref: UMLS:C0228171 [Term] id: UBERON:0005911 ! endo-epithelium name: endo-epithelium def: "Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA]" [FMA:69065] xref: FMA:69065 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_from UBERON:0000925 ! endoderm [Term] id: UBERON:0012275 name: meso-epithelium def: "Epithelium that derives from the mesoderm. [Automatically generated definition]." [OBOL:automatic] xref: FMA:86452 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_from UBERON:0000926 ! mesoderm [Term] id: UBERON:0005910 ! transitional epithelium name: transitional epithelium def: "Multilaminar epithelium, which of consists of more than one layer of epithelial cells, in contact with a basement membrane, that can undergo distention and contraction without losing its integrity and consistency. Examples: urothelium.[FMA]" [FMA:63914, Wikipedia:Transitional_epithelium, FMA:FMA] comment: see comments for urothelium synonym: "epithelium transitionale" EXACT [FMA:63914] synonym: "urothelium" NARROW [Wikipedia:Transitional_epithelium, EMAPA:28089] xref: FMA:63914 ! transitional epithelium xref: BTO:0003906 ! uroepithelium (also: UBERON:0000365 'urothelium') xref: MESH:A10.272.850 ! urothelium (also: UBERON:0000365 'urothelium') is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0000486 ! multilaminar epithelium xref: ncithesaurus:Transitional_Epithelium ! Transitional Epithelium (also: UBERON:0004645 'urinary bladder urothelium') xref: SCTID:30117005 ! Transitional epithelium xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Harnblase_Urothel.png xref: UMLS:C0225339 [Term] id: UBERON:0011945 ! luminal layer of epithelium name: luminal layer of epithelium is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0000483 ! epithelium [Term] id: UBERON:0011946 name: subluminal layer of epithelium is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0000483 ! epithelium [Term] id: UBERON:0000365 ! urothelium name: urothelium def: "The urothelium is the epithelial tissue layer that lines much of the urinary tract, including the renal pelvis, the ureters, the bladder, and parts of the urethra." [Wikipedia:Urothelium] comment: consider merging with transitional epithelium. MA uses the label 'urothelium' exclusively. FMA uses 'transitional epithelium' and has 'urothelium' as a sibling. FMA also lists 'urothelium' as the only example of 'transitional epithelium' synonym: "uroepithelium" EXACT [FMA:67695] synonym: "transitional epithelium" BROAD INCONSISTENT [] xref: FMA:67695 ! Urothelium xref: ncithesaurus:Urothelium ! Urothelium xref: GAID:935 ! urothelium xref: EMAPA:28089 ! urothelium xref: MESH:A10.272.850 ! urothelium (also: UBERON:0005910 'transitional epithelium') xref: BTO:0003906 ! uroepithelium (also: UBERON:0005910 'transitional epithelium') intersection_of: UBERON:0005910 ! transitional epithelium intersection_of: part_of UBERON:0001008 ! urinary system xref: SCTID:57789003 ! Urothelium xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Harnblase_Urothel.png property_value: has_relational_adjective "urothelial" xsd:string xref: UMLS:C0227598 [Term] id: UBERON:0001254 name: urothelium of ureter def: "the luminal epithelium of the tube that conducts the urine from the renal pelvis to the bladder[MP,unvetted]" [MP:0000535] comment: AO notes: MP treats ureter urothelium and ureter luminal urothelium as exact synonyms, yes MA treats these as distinct; see also: transitional epithelium vs urothelium synonym: "ureter transitional epithelium" EXACT [] synonym: "ureter urothelium" EXACT [] synonym: "ureter luminal urothelium" RELATED INCONSISTENT [MP:0000535] synonym: "transitional epithelium of ureter" EXACT [] xref: FMA:15897 ! Transitional epithelium of ureter xref: MA:0002655 ! ureter urothelium intersection_of: UBERON:0000365 ! urothelium intersection_of: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0011947 name: ureter luminal urothelium intersection_of: UBERON:0011945 ! luminal layer of epithelium intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0001254 ! urothelium of ureter xref: MA:0002656 ! ureter luminal urothelium def: "A luminal layer of epithelium that is part of a ureter." [OBOL:automatic] [Term] id: UBERON:0011948 name: ureter subluminal urothelium is_a: UBERON:0011946 ! subluminal layer of epithelium relationship: part_of UBERON:0001254 ! urothelium of ureter xref: MA:0002657 ! ureter subluminal urothelium [Term] id: UBERON:0011949 name: endometrium luminal epithelium intersection_of: UBERON:0011945 ! luminal layer of epithelium intersection_of: part_of UBERON:0004811 ! endometrium epithelium xref: MA:0002733 ! endometrium luminal epithelium def: "A luminal layer of epithelium that is part of a endometrium epithelium." [OBOL:automatic] [Term] id: UBERON:0011950 name: mammary gland luminal epithelium intersection_of: UBERON:0011945 ! luminal layer of epithelium intersection_of: part_of UBERON:0001911 ! mammary gland xref: FMA:74458 ! lumina layer of epithelium of lactiferous gland synonym: "lumina layer of epithelium of lactiferous gland" EXACT [FMA:74458] def: "A luminal layer of epithelium that is part of a mammary gland." [OBOL:automatic] relationship: part_of UBERON:0003244 {is_inferred="true", source="reference_0000032"} ! epithelium of mammary gland [Term] id: UBERON:0011951 name: prostate luminal epithelium intersection_of: UBERON:0011945 ! luminal layer of epithelium intersection_of: part_of UBERON:0002367 ! prostate gland xref: FMA:74262 ! subdivision of luminal layer of epithelium of prostatic gland synonym: "subdivision of luminal layer of epithelium of prostatic gland" EXACT [FMA:74262] def: "A luminal layer of epithelium that is part of a prostate gland." [OBOL:automatic] relationship: part_of UBERON:0000428 {is_inferred="true", source="reference_0000032"} ! prostate epithelium [Term] id: UBERON:0004645 name: urinary bladder urothelium synonym: "transitional epithelium" RELATED [MA:0001693] synonym: "bladder transitional cell epithelium" EXACT [FMA:15936] synonym: "urinary bladder transitional epithelium" EXACT [FMA:15936] synonym: "urothelium of urinary bladder" EXACT [FMA:15936] synonym: "transitional epithelium of urinary bladder" EXACT [FMA:15936] synonym: "urothelium" BROAD [BTO:0001245] xref: FMA:15936 ! Transitional epithelium of urinary bladder xref: MA:0001693 ! urinary bladder urothelium xref: BTO:0001694 ! urinary bladder epithelium intersection_of: UBERON:0000365 ! urothelium intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001259 ! mucosa of urinary bladder xref: ncithesaurus:Transitional_Epithelium ! Transitional Epithelium (also: UBERON:0005910 'transitional epithelium') xref: SCTID:25631003 ! Urinary bladder transitional epithelium def: "An urothelium that is part of a urinary bladder." [OBOL:automatic] xref: UMLS:C0225339 [Term] id: UBERON:0004787 name: urethra urothelium def: "An urothelium that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "uroepithelium of urethra" EXACT [OBOL:automatic] synonym: "urethra Uroepithelium" EXACT [OBOL:automatic] synonym: "urothelium of urethra" EXACT [OBOL:automatic] xref: MA:0001687 ! urethra urothelium intersection_of: UBERON:0000365 ! urothelium intersection_of: part_of UBERON:0000057 ! part_of urethra xref: ncithesaurus:Urethra_Transitional_Cell_Epithelium ! Urethra Urothelium xref: UMLS:C1710585 [Term] id: UBERON:0004788 name: kidney pelvis urothelium def: "An urothelium that is part of a renal pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "transitional epithelium of renal pelvis" EXACT [FMA:263264] synonym: "transitional epithelium of kidney pelvis" EXACT [OBOL:automatic] synonym: "kidney pelvis transitional epithelium" EXACT [OBOL:automatic] synonym: "renal pelvis transitional epithelium" EXACT [OBOL:automatic] synonym: "uroepithelium of kidney pelvis" EXACT [OBOL:automatic] synonym: "uroepithelium of pelvis of ureter" EXACT [OBOL:automatic] synonym: "uroepithelium of renal pelvis" EXACT [OBOL:automatic] synonym: "kidney pelvis Uroepithelium" EXACT [OBOL:automatic] synonym: "pelvis of ureter Uroepithelium" EXACT [OBOL:automatic] synonym: "pelvis of ureter urothelium" EXACT [OBOL:automatic] synonym: "renal pelvis Uroepithelium" EXACT [OBOL:automatic] synonym: "renal pelvis urothelium" EXACT [OBOL:automatic] synonym: "urothelium of kidney pelvis" EXACT [OBOL:automatic] synonym: "urothelium of pelvis of ureter" EXACT [OBOL:automatic] synonym: "urothelium of renal pelvis" EXACT [OBOL:automatic] xref: MA:0002632 ! kidney pelvis urothelium xref: FMA:263264 ! transitional epithelium of renal pelvis intersection_of: UBERON:0000365 ! urothelium intersection_of: part_of UBERON:0001224 ! part_of renal pelvis xref: ncithesaurus:Renal_Pelvis_Urothelium ! Renal Pelvis Urothelium xref: UMLS:C1709899 [Term] id: UBERON:0005912 name: transitional epithelium of major calyx synonym: "urothelium of major calyx" EXACT [OBOL:automatic] xref: FMA:263266 ! transitional epithelium of major calyx intersection_of: UBERON:0001254 ! urothelium of ureter intersection_of: part_of UBERON:0005007 ! mucosa of major calyx def: "An urothelium of ureter that is part of a mucosa of major calyx." [OBOL:automatic] [Term] id: UBERON:0004646 name: infraorbital artery def: "The infraorbital artery is an artery in the head that runs in the maxilla, emerging through the infraorbital foramen, just under the orbit of the eye. [WP,unvetted]." [Wikipedia:Infraorbital_artery] synonym: "infra-orbital artery" EXACT [FMA:49767] xref: FMA:49767 ! Infra-orbital artery xref: MA:0001977 ! infraorbital artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Gray511.png/200px-Gray511.png is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0001616 ! maxillary artery xref: ncithesaurus:Infraorbital_Artery ! Infraorbital Artery xref: SCTID:148167004 ! Entire infraorbital artery synonym: "a. infraorbitalis" RELATED LATIN [Wikipedia:Infraorbital_artery] xref: http://upload.wikimedia.org/wikipedia/commons/a/aa/Gray511.png xref: UMLS:C0226153 [Term] id: UBERON:0004647 name: liver lobule def: "a small division of the liver defined at the histological scale, the functional unit of which is the hepatic acinus." [Wikipedia:Lobules_of_liver] comment: should not be confused with the anatomic lobes of the liver (caudate lobe, quadrate lobe, left lobe, and right lobe), or any of the functional lobe classification systems.[WP] synonym: "lobules of liver" RELATED PLURAL [Wikipedia:Lobules_of_liver] synonym: "lobuli hepatis" RELATED LATIN [Wikipedia:Lobules_of_liver] synonym: "lobuli hepatici" EXACT PLURAL [] synonym: "hepatic lobule" EXACT [FMA:14471] synonym: "lobulus hepaticus" EXACT LATIN [FMA:14471] xref: FMA:14471 ! hepatic lobule xref: MA:0002494 ! liver lobule is_a: UBERON:0000064 {source="FMA"} ! organ part relationship: part_of UBERON:0001280 {source="FMA", source="MA"} ! liver parenchyma xref: ncithesaurus:Hepatic_Lobule ! Hepatic Lobule xref: SCTID:362194004 ! Entire hepatic lobule xref: UMLS:C0227518 [Term] id: UBERON:0006718 name: medial pterygoid muscle def: "The medial pterygoid (or internal pterygoid muscle), is a thick, quadrilateral muscle of mastication. The mandibular branch of the fifth cranial nerve, the trigeminal nerve, innervates the medial pterygoid muscle." [Wikipedia:Medial_pterygoid_muscle] synonym: "internal pterygoid muscle" RELATED [] synonym: "internal pterygoid" RELATED [Wikipedia:Medial_pterygoid_muscle] synonym: "medial pterygoid" RELATED [Wikipedia:Medial_pterygoid_muscle] synonym: "pterygoidei internus" RELATED [Wikipedia:Medial_pterygoid_muscle] synonym: "pterygoideus internus" RELATED [Wikipedia:Medial_pterygoid_muscle] synonym: "pterygoideus medial" EXACT [Wikipedia:Medial_pterygoid_muscle] synonym: "pterygoideus medialis" EXACT [Wikipedia:Medial_pterygoid_muscle] synonym: "pterygoid medialis" EXACT [MA:0002361] synonym: "musculus pterygoideus medialis" EXACT LATIN [Wikipedia:Medial_pterygoid_muscle] synonym: "musculus pterygoideus internus" EXACT LATIN [Wikipedia:Medial_pterygoid_muscle] xref: FMA:49011 ! medial pterygoid xref: MA:0002361 ! pterygoid medialis xref: EMAPA:25141 ! medial xref: BTO:0005226 ! medial pterygoid muscle is_a: UBERON:0006720 ! pterygoid muscle xref: SCTID:244771003 ! Entire medial pterygoid muscle xref: ncithesaurus:Internal_Pterygoid_Muscle ! Internal Pterygoid Muscle relationship: has_muscle_insertion UBERON:0001684 {source="dbpedia", notes="medial angle of the mandible"} ! mandible relationship: innervated_by UBERON:0000375 {source="dbpedia", notes="mandibular nerve via nerve to medial pterygoid"} ! mandibular nerve xref: http://upload.wikimedia.org/wikipedia/commons/e/ec/Musculuspterygoideusmedialis.png property_value: external_definition "The medial pterygoid is a pharyngeal arch 1 muscle that participates in oral/pharyngeal behaviors and is innervated by the nerve to the medial pterygoid and attaches to the cranial base and the medial side of the mandibular angle.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C1512882 [Term] id: UBERON:0006719 name: lateral pterygoid muscle def: "The lateral pterygoid (or external pterygoid) is a muscle of mastication with two heads." [Wikipedia:Lateral_pterygoid_muscle] synonym: "external pterygoid muscle" RELATED [Wikipedia:Lateral_pterygoid_muscle] synonym: "lateral pteregoid" RELATED [Wikipedia:Lateral_pterygoid_muscle] synonym: "lateral pteregoid muscle" RELATED [Wikipedia:Lateral_pterygoid_muscle] synonym: "lateral pterygoid" RELATED [Wikipedia:Lateral_pterygoid_muscle] synonym: "pterygoideus externus" RELATED [Wikipedia:Lateral_pterygoid_muscle] synonym: "pterygoideus externus muscle" RELATED [Wikipedia:Lateral_pterygoid_muscle] synonym: "pterygoideus lateral" EXACT [Wikipedia:Lateral_pterygoid_muscle] synonym: "pterygoideus lateral muscle" EXACT [Wikipedia:Lateral_pterygoid_muscle] synonym: "lateral pterygoid" BROAD [FMA:49015] synonym: "musculus pterygoides lateralis" EXACT [FMA:49015] synonym: "pterygoid lateralis" BROAD [MA:0002360] synonym: "m. pterygoideus lateralis" RELATED LATIN [Wikipedia:Lateral_pterygoid_muscle] synonym: "m. pterygoideus externus" RELATED LATIN [Wikipedia:Lateral_pterygoid_muscle] synonym: "musculus pterygoideus lateralis" RELATED LATIN [Wikipedia:Lateral_pterygoid_muscle] synonym: "musculus pterygoideus externus" RELATED LATIN [Wikipedia:Lateral_pterygoid_muscle] xref: FMA:49015 ! lateral pterygoid xref: MA:0002360 ! pterygoid lateralis xref: EMAPA:25140 ! lateral of pterygoid is_a: UBERON:0006720 ! pterygoid muscle xref: ncithesaurus:External_Pterygoid_Muscle ! External Pterygoid Muscle xref: SCTID:244772005 ! Entire lateral pterygoid muscle relationship: innervated_by UBERON:0000375 {source="dbpedia", is_indirect="true", notes="lateral pterygoid nerve from the mandibular nerve"} ! mandibular nerve relationship: innervated_by UBERON:0013647 ! lateral pterygoid nerve relationship: has_muscle_origin UBERON:0004649 {source="dbpedia", notes="Great wing of sphenoid and pterygoid plate"} ! sphenoid bone pterygoid process relationship: has_muscle_insertion UBERON:0004657 {source="dbpedia"} ! mandible condylar process xref: http://upload.wikimedia.org/wikipedia/commons/b/bb/Musculuspterygoideuslateralis.png property_value: external_definition "Pharyngeal arch 1 muscle that participates in oral/pharyngeal behaviors, is innervated by the lateral pterygoid nerve branches, and attaches to the condylar process of the mandible and TMJ capsule, and the cranial base.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C1517045 [Term] id: UBERON:0006720 ! pterygoid muscle alt_id: UBERON:3010730 ! pterygoideus name: pterygoid muscle subset: grouping_class synonym: "pterygoid" RELATED INCONSISTENT [EMAPA:25139] synonym: "pterygoideus" RELATED [] synonym: "pterygoideus muscle" RELATED [] xref: GAID:147 ! pterygoid muscle xref: EMAPA:25139 ! pterygoid xref: MESH:A02.633.567.600.700 ! pterygoid muscle is_a: UBERON:0003681 ! masticatory muscle relationship: innervated_by UBERON:0000375 {source="dbpedia", notes="generalized"} ! mandibular nerve relationship: has_muscle_insertion UBERON:0001684 {source="dbpedia", notes="generalized"} ! mandible xref: SCTID:244770002 ! Entire pterygoid muscle xref: AAO:0010730 ! pterygoideus [Term] id: UBERON:0004649 name: sphenoid bone pterygoid process def: "The pterygoid processes of the sphenoid, one on either side, descend perpendicularly from the regions where the body and great wings unite. Each process consists of a medial pterygoid plate and a lateral pterygoid plate, the upper parts of which are fused anteriorly; a vertical sulcus, the pterygopalatine groove, descends on the front of the line of fusion. The plates are separated below by an angular cleft, the pterygoid fissure (or pterygoid notch), the margins of which are rough for articulation with the pyramidal process of the palatine bone. The two plates diverge behind and enclose between them a V-shaped fossa, the pterygoid fossa, which contains pterygoideus internus and tensor veli palatini. Above this fossa is a small, oval, shallow depression, the scaphoid fossa, which gives origin to the tensor veli palatini. The anterior surface of the pterygoid process is broad and triangular near its root, where it forms the posterior wall of the pterygopalatine fossa and presents the anterior orifice of the pterygoid canal." [Wikipedia:Pterygoid_processes_of_the_sphenoid] comment: todo - check AAO:0000521-pterygoid and MA:0001471-pterygoid bone. MA also has 'inner plate of pterygoid process' as a syn for MA:0001471, FMA has lateral/medial plates. Seems likely inner = lateral (see MP:0004452). synonym: "pterygoid plate" RELATED [Wikipedia:Pterygoid_processes_of_the_sphenoid] synonym: "pterygoid process" RELATED [Wikipedia:Pterygoid_processes_of_the_sphenoid] synonym: "pterygoid processes" RELATED [Wikipedia:Pterygoid_processes_of_the_sphenoid] synonym: "pterygoid processus" RELATED [Wikipedia:Pterygoid_processes_of_the_sphenoid] synonym: "pterygoid process of sphenoid bone" RELATED [MA:0002774] synonym: "processus pterygoideus" EXACT [FMA:54682] synonym: "pterygoid process of sphenoid" EXACT [FMA:54682] synonym: "pterygoid process of sphenoid bone" EXACT [FMA:54682] synonym: "pterygoid process" EXACT [FMA:54682] xref: FMA:54682 ! Pterygoid process xref: MA:0002774 ! sphenoid bone pterygoid process is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0001677 ! sphenoid bone synonym: "processus pterygoideus ossis sphenoidalis" EXACT LATIN [FMA:TA, FMA:54682] xref: AAO:0010086 ! pterygoid process xref: SCTID:140390001 ! Entire pterygoid process of sphenoid bone synonym: "processus pterygoideus ossis sphenoidalis" RELATED LATIN [Wikipedia:Pterygoid_processes_of_the_sphenoid] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Gray145.png property_value: external_definition "Process that projects from posterior margin of commissure into subocular space.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010086", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of anterior quadratocranial commissure (AAO:0010061)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010086", date_retrieved="2012-06-20"} relationship: in_lateral_side_of UBERON:0001677 {source="FMA-abduced-lr"} ! sphenoid bone [Term] id: UBERON:0010389 name: pterygoid bone def: "a bone which corresponds to the inner plate of the pterygoid process of the human skull, but which, in all vertebrates below mammals, is not connected with the posterior nares, but serves to connect the palatine bones with the point of suspension of the lower jaw" [http://www.websters-online-dictionary.org/definitions/Pterygoid+bone] comment: Sources vary as to whether the pterygoid corresponds to the pterygoid processes in general, or the latter/inner plate. synonym: "inner plate of pterygoid process" RELATED [MA:0001471] synonym: "lamina lateralis (processus pterygoideus)" EXACT [FMA:54687, MP:0004452] synonym: "lamina lateralis processi pterygoideus ossis sphenoidalis" EXACT LATIN [FMA:TA, MP:0004452] synonym: "lateral lamina of pterygoid process" EXACT [FMA:54687, MP:0004452] synonym: "lateral plate of sphenoid" EXACT [FMA:54687, MP:0004452] synonym: "lateral plate of pterygoid process" EXACT [FMA:54687, MP:0004452] synonym: "lateral pterygoid plate" EXACT [] synonym: "pterygoid" RELATED [AAO:0000521] is_a: UBERON:0011164 {source="MA"} ! neurocranium bone relationship: part_of UBERON:0004649 {source="MA"} ! sphenoid bone pterygoid process relationship: part_of UBERON:0012072 {source="Paleos", source="Kardong"} ! palatal part of dermatocranium relationship: part_of UBERON:0003108 {source="AAO"} ! suspensorium xref: MA:0001471 ! pterygoid bone xref: FMA:54687 ! lateral plate of pterygoid process xref: SCTID:415639001 ! Structure of lateral pterygoid plate xref: AAO:0000521 ! pterygoid property_value: external_definition "Palatal bones of intramembranous origin that lie anterior to the otic capsules, lateral to the orbits, and medial to the maxillae.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000521", date_retrieved="2012-09-17", source="AAO"} property_value: external_definition "In tetrapods, the pterygoid is a complex, but relatively stable, paired palatal bone with a number of parts. For the following discussion, it may be best to refer to the images of tetrapod palates at, for example Ornithosuchus, Therapsida, or Palatines. In many tetrapods, it is the largest palatal bone and serves as the main structural support. Most typically, the pterygoids meet extensively on the mid-line of the palate and jointly send a process, the palatal ramus, anteriorly, which may cover the parasphenoid more or less completely. Sometimes this term is used to include the main body of the pterygoid as well. More variably, there are one or two anterolateral processes which go by various names, such as ectopterygoid ramus. In many amniotes, the pterygoid develops a strong transverse process or transverse flange which forms a bar running laterally across the palate. The pterygoid also articulates with (where present) the dorsoventral supports for the palate: the epipterygoid (dorsal) and the basipterygoid process of the braincase. Finally, the pterygoid sends a long, robust quadrate ramus with complex curvature down (posteroventrally) to grasp the quadrate and support the jaw articulation. Basally, in fishes, the terminology tends to be a little different. Refer to the image of the Frasnian actinistian Diplocercides. The pterygoid bone of tetrapods is, roughly speaking, derived from the middle, entopterygoid (see also entry at entopterygoid for alternative definitions) portion of the palatoquadrate complex. The entopterygoid is not actually a part of the palatoquadrate. It is a dermal bone which has replaced the middle section of the primitively continuous endochondral bone of the palatoquadrate, the original upper jaw. In tetrapods, the pterygoid advances further, and also replaces the central part of the posterior, pterygoquadrate unit. This becomes the quadrate ramus. The upper part of this unit, the portion involved in the dorsal and basipterygoid articulations between jaw and braincase, is referred to as the metapterygoid. In tetrapods, most of this region is incorporated into the pterygoid as well, with the exception of the ascending process of the palatoquadrate, which becomes the epipterygoid. Since the anterior braincase articulation is lost in tetrapods, the only remaining sections of the palatoquadrate are the epipterygoid and the quadrate (or, in mammals, the incus). Everything else is either lost or is replaced by the pterygoid[Palaeos]" xsd:string {source="http://palaeos.com/vertebrates/glossary/glossaryPte.html"} property_value: external_definition "In tetrapods, the pterygoid is a complex, but relatively stable, paired palatal bone with a number of parts. In many tetrapods, it is the largest palatal bone and serves as the main structural support. Most typically, the pterygoids meet extensively on the mid-line of the palate and jointly send a process, the palatal ramus, anteriorly, which may cover the parasphenoid more or less completely. Sometimes this term is used to include the main body of the pterygoid as well. More variably, there are one or two anterolateral processes which go by various names, such as ectopterygoid ramus. In many amniotes, the pterygoid develops a strong transverse process or transverse flange which forms a bar running laterally across the palate. The pterygoid also articulates with (where present) the dorsoventral supports for the palate: the epipterygoid (dorsal) and the basipterygoid process of the braincase. Finally, the pterygoid sends a long, robust quadrate ramus with complex curvature down (posteroventrally) to grasp the quadrate and support the jaw articulation. The pterygoid bone of tetrapods is, roughly speaking, derived from the middle entopterygoid portion of the palatoquadrate complex of fishes. The entopterygoid is not actually a part of the palatoquadrate. It is a dermal bone which has replaced the middle section of the primitively continuous endochondral bone of the palatoquadrate, the original upper jaw. In tetrapods, the pterygoid advances further, and also replaces the central part of the posterior, pterygoquadrate unit. This becomes the quadrate ramus. The upper part of this unit, the portion involved in the dorsal and basipterygoid articulations between jaw and braincase, is referred to as the metapterygoid. In tetrapods, most of this region is incorporated into the pterygoid as well, with the exception of the ascending process of the palatoquadrate, which becomes the epipterygoid." xsd:string {date_retrieved="2012-09-17", source="http://palaeos.com/vertebrates/glossary/glossaryPte.html"} [Term] id: UBERON:0004652 name: humerus diaphysis def: "The body or shaft of the humerus is almost cylindrical in the upper half of its extent, prismatic and flattened below, and has three borders and three surfaces." [Wikipedia:Body_of_humerus] synonym: "body of the humerus" RELATED [Wikipedia:Body_of_humerus] synonym: "medial humerus" RELATED [Wikipedia:Body_of_humerus] synonym: "shaft of the humerus" RELATED [Wikipedia:Body_of_humerus] synonym: "body of humerus" EXACT [FMA:13305] synonym: "humeral diaphysis" EXACT [FMA:13305] synonym: "shaft of humerus" EXACT [FMA:13305] synonym: "diaphysis of humerus" EXACT [FMA:13305] xref: FMA:13305 ! Diaphysis of humerus xref: MA:0002807 ! humerus diaphysis xref: EMAPA:25051 ! shaft intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0000976 ! humerus synonym: "corpus humeri" EXACT LATIN [FMA:TA, FMA:13305] xref: SCTID:181927007 ! Entire shaft of humerus [Term] id: UBERON:0004654 name: temporal process of zygomatic bone def: "The temporal process of the zygomatic bone, directed backward and medialward, is concave, presenting medially a rough, triangular area, for articulation with the maxilla, and laterally a smooth, concave surface, the upper part of which forms the anterior boundary of the temporal fossa, the lower a part of the infratemporal fossa. Near the center of this surface is the zygomaticotemporal foramen for the transmission of the zygomaticotemporal nerve." [Wikipedia:Temporal_process_of_the_zygomatic_bone] synonym: "processus temporalis (os zygomaticum)" EXACT [FMA:52904] synonym: "zygomatic bone temporal process" EXACT [MA:0002812] synonym: "facies temporalis ossis zygomatici" EXACT LATIN [Wikipedia:Temporal_process_of_the_zygomatic_bone] xref: FMA:52904 ! Temporal process of zygomatic bone xref: MA:0002812 ! zygomatic bone temporal process xref: http://upload.wikimedia.org/wikipedia/commons/thumb/d/da/Gray166.png/200px-Gray166.png is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0001683 {source="MA"} ! zygomatic bone relationship: part_of UBERON:0002500 {source="MA"} ! zygomatic arch xref: SCTID:122772003 ! Temporal process of zygomatic bone xref: http://upload.wikimedia.org/wikipedia/commons/d/da/Gray166.png [Term] id: UBERON:0004655 name: zygomatic process of temporal bone alt_id: UBERON:0004653 def: "The zygomatic process of the temporal bone is a long, arched process projecting from the lower part of the squamous portion of the temporal bone. It articulates with the zygomatic bone. This process is at first directed lateralward, its two surfaces looking upward and downward; it then appears as if twisted inward upon itself, and runs forward, its surfaces now looking medialward and lateralward." [Wikipedia:Zygomatic_process_of_temporal_bone] synonym: "processus zygomaticus" EXACT [FMA:52886] synonym: "temporal zygomatic process" EXACT [FMA:52886] synonym: "temporal bone zygomatic process" EXACT [MA:0002811] synonym: "processus zygomaticus ossis temporalis" EXACT LATIN [Wikipedia:Zygomatic_process_of_temporal_bone] xref: FMA:52886 ! Zygomatic process of temporal bone xref: MA:0002811 ! temporal bone zygomatic process xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/96/Gray137.png/200px-Gray137.png xref: EMAPA:19015 ! zygomatic process is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0001678 {source="MA"} ! temporal bone relationship: part_of UBERON:0002500 {source="MA"} ! zygomatic arch xref: SCTID:414110008 ! Entire zygomatic process of temporal bone xref: http://upload.wikimedia.org/wikipedia/commons/9/96/Gray137.png [Term] id: UBERON:0013217 name: zygomatic plate def: "In rodent anatomy, the zygomatic plate is a bony plate derived from the flattened front part of the zygomatic arch (cheekbone). At the back, it connects to the front (maxillary) root of the zygomatic arch, and at the top it is connected to the rest of the skull via the antorbital bridge. It is part of the maxillary bone, or upper jaw, which also contains the upper cheekteeth. Primitively, rodents have a nearly horizontal zygomatic plate. In association with specializations in zygomasseteric system, several distinct morphologies have developed across the order. The term is also used for an analogous structure in some South American typotheres, including Pseudotypotherium and Medistylus." [Wikipedia:Zygomatic_plate] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0002500 ! zygomatic arch relationship: part_of UBERON:0002397 ! maxilla [Term] id: UBERON:0004657 name: mandible condylar process def: "The posterior process on the ramus of the mandible composed of two parts: a superior part, the articular portion, and an inferior part, the condylar neck." [BTO:0001750, Wikipedia:Condyloid_process] synonym: "condyle of mandible" RELATED [Wikipedia:Condyloid_process] synonym: "condyle of the mandible" RELATED [Wikipedia:Condyloid_process] synonym: "condyloid process" RELATED [Wikipedia:Condyloid_process] synonym: "mandibular condyloid process" RELATED [MA:0002816] synonym: "processus condylaris" EXACT [FMA:52836] synonym: "condylar process of mandible" EXACT [FMA:52836] synonym: "mandibular condyle" EXACT [BTO:0001750] xref: FMA:52836 ! Condylar process of mandible xref: MA:0002816 ! mandible condylar process xref: GAID:219 ! mandibular condyle xref: BTO:0001750 ! mandibular condyle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Processuscondylarismandibulae.PNG/200px-Processuscondylarismandibulae.PNG xref: MESH:A02.835.232.781.324.502.632.600 ! mandibular condyle is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0001684 ! mandible relationship: part_of UBERON:0000401 ! mandibular ramus [Term] id: UBERON:0011309 name: body of mandible def: "The body of the mandible is curved somewhat like a horseshoe and has two surfaces and two borders." [Wikipedia:Body_of_mandible] synonym: "body of the mandible" RELATED [Wikipedia:Body_of_mandible] synonym: "mandibular body" EXACT [FMA:52827] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001684 {source="FMA"} ! mandible xref: FMA:52827 ! body of mandible xref: SCTID:244684002 ! Entire body of mandible [Term] id: UBERON:0011310 name: masseteric fossa def: ".The fossa for the masseter. In some therapsids, the coronoid process of the dentary bears a large external depression which accommodates the masseter -- an important muscle in closing and in grinding motions of the jaw." [http://palaeos.com/vertebrates/glossary/glossaryM.html] synonym: "masseteric cavity" RELATED [] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001684 {source="FMA"} ! mandible property_value: external_definition "fossa on the lateral surface of the mandible, located in the superior part of the ascending process.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} [Term] id: UBERON:0004658 name: mandible head synonym: "Mandibular head" EXACT [FMA:59331] synonym: "head of mandible" EXACT [FMA:59331] xref: FMA:59331 ! Head of mandible xref: MA:0002817 ! mandible head is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004657 ! mandible condylar process xref: SCTID:51354009 ! Head of mandible [Term] id: UBERON:0004659 name: mandible neck synonym: "Mandibular neck" EXACT [FMA:59332] synonym: "neck of mandible" EXACT [FMA:59332] xref: FMA:59332 ! Neck of mandible xref: MA:0002818 ! mandible neck is_a: UBERON:0001560 ! neck of organ relationship: part_of UBERON:0001684 ! mandible relationship: part_of UBERON:0004657 ! mandible condylar process xref: SCTID:368875004 ! Entire neck of mandible [Term] id: UBERON:0011598 name: coronoid bone synonym: "coronoid process" BROAD [TAO:0001673] is_a: UBERON:0008907 {source="AAO"} ! dermal bone relationship: part_of UBERON:0003278 {source="AAO"} ! skeleton of lower jaw relationship: part_of UBERON:0003113 {source="Kardong", notes="mandibular series"} ! dermatocranium xref: AAO:0000103 ! coronoid xref: TAO:0001673 ! coronoid process [Term] id: UBERON:0004660 name: mandible coronoid process def: "a dorsal process on the lower jaw associated with muscle attachment. It may be formed by a separate coronoid bone or as a process of the dentary. In most living (and many extinct) mammals, the most dorsal of the three proximal processes of the jaw." [Wikipedia:Coronoid_process_of_the_mandible, http://palaeos.com/vertebrates/glossary/glossaryCh.html#Coronoid%20process] comment: AO notes: TAO:0001673 coronoid process, a bony projection on dentary synonym: "mandibular coronoid process" RELATED [MA:0002819] synonym: "processus coronoideus (mandibula)" EXACT [FMA:52833] synonym: "coronoid process of mandible" EXACT [FMA:52833] synonym: "coronoid" BROAD [AAO:0000103] xref: FMA:52833 ! Coronoid process of mandible xref: MA:0002819 ! mandible coronoid process is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0001684 ! mandible relationship: part_of UBERON:0000401 ! mandibular ramus xref: SCTID:244691004 ! Entire coronoid process of mandible synonym: "processus coronoideus mandibulae" RELATED LATIN [Wikipedia:Coronoid_process_of_the_mandible] xref: http://upload.wikimedia.org/wikipedia/commons/7/74/Processuscoronoideusmandibulae.PNG [Term] id: UBERON:0010994 name: coronoid process of ulna def: "The coronoid process is a triangular eminence projecting forward from the upper and front part of the ulna. Its base is continuous with the body of the bone, and of considerable strength. Its apex is pointed, slightly curved upward, and in flexion of the forearm is received into the coronoid fossa of the humerus. Its upper surface is smooth, concave, and forms the lower part of the semilunar notch. Its antero-inferior surface is concave, and marked by a rough impression for the insertion of the Brachialis muscle. At the junction of this surface with the front of the body is a rough eminence, the tuberosity of the ulna, which gives insertion to a part of the Brachialis; to the lateral border of this tuberosity the oblique cord is attached. Its lateral surface presents a narrow, oblong, articular depression, the radial notch. Its medial surface, by its prominent, free margin, serves for the attachment of part of the ulnar collateral ligament. At the front part of this surface is a small rounded eminence for the origin of one head of the Flexor digitorum superficialis muscle; behind the eminence is a depression for part of the origin of the Flexor digitorum profundus muscle; descending from the eminence is a ridge which gives origin to one head of the Pronator teres muscle. Frequently, the Flexor pollicis longus muscle arises from the lower part of the coronoid process by a rounded bundle of muscular fibers." [Wikipedia:Coronoid_process_of_the_ulna] synonym: "coronoid process of the ulna" EXACT [Wikipedia:Coronoid_process_of_the_ulna] synonym: "ulnar coronoid process" EXACT [] synonym: "coronoid process" BROAD [FMA:23616] synonym: "processus coronoideus" EXACT [FMA:23616] is_a: UBERON:0004529 {source="FMA"} ! anatomical projection relationship: part_of UBERON:0006822 {source="FMA"} ! proximal epiphysis of ulna disjoint_from: UBERON:0004661 ! mandible temporal crest xref: FMA:23616 ! coronoid process of ulna xref: SCTID:181951002 ! Entire coronoid process of ulna synonym: "processus coronoideus ulnae" RELATED LATIN [Wikipedia:Coronoid_process_of_the_ulna] xref: http://upload.wikimedia.org/wikipedia/commons/6/60/Gray212.png [Term] id: UBERON:0004661 ! mandible temporal crest name: mandible temporal crest synonym: "Crista temporalis (Mandibulae)" EXACT [FMA:59484] synonym: "temporal crest of mandible" EXACT [FMA:59484] xref: FMA:59484 ! Temporal crest of mandible xref: MA:0002820 ! mandible temporal crest is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001684 ! mandible relationship: part_of UBERON:0000401 ! mandibular ramus [Term] id: UBERON:0004662 name: vertebra lamina synonym: "vertebral lamina" RELATED [MA:0002876] synonym: "lamina of vertebral arch" EXACT [FMA:11951] synonym: "vertebral lamina" EXACT [FMA:11951] synonym: "lamina of vertebra" EXACT [FMA:11951] synonym: "neural arch lamina" EXACT [AAO:0000695] xref: FMA:11951 ! Lamina of vertebra xref: MA:0002876 ! vertebra lamina xref: AAO:0000695 ! neural arch lamina is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0003861 ! neural arch relationship: part_of UBERON:0002412 ! vertebra synonym: "lamina arcus vertebrae" EXACT LATIN [FMA:TA, FMA:11951] xref: SCTID:277423002 ! Entire lamina of vertebra property_value: external_definition "Paired plates that form the neural arch. The lateral margin of each lamina rests dorsal to the superior end of the pedicel, and the medial end fuses to the medial end of the opposite lamina.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000695", date_retrieved="2012-06-20", source="AAO:Pugener_and_Maglia_2008"} [Term] id: UBERON:0004663 name: aorta wall def: "An anatomical wall that is part of an aorta [Automatically generated definition]." [OBOL:automatic] synonym: "Aortic wall" EXACT [FMA:14156] synonym: "wall of aorta" EXACT [FMA:14156] xref: FMA:14156 ! Wall of aorta xref: MA:0002901 ! aorta wall intersection_of: UBERON:0000060 ! wall intersection_of: part_of UBERON:0000947 ! aorta [Term] id: UBERON:0004664 name: aorta tunica adventitia synonym: "tunica adventitia of aorta" EXACT [FMA:14283] xref: FMA:14283 ! Tunica adventitia of aorta xref: MA:0002902 ! aorta tunica adventitia intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: part_of UBERON:0000947 ! part_of aorta relationship: part_of UBERON:0004663 ! aorta wall xref: SCTID:24996002 ! Aortic tunica adventitia def: "A tunica adventitia that is part of a aorta." [OBOL:automatic] [Term] id: UBERON:0007240 name: tunica adventitia of artery synonym: "tunica externa (adventitia)(arteriae)" EXACT [FMA:14274] synonym: "arterial adventitia" EXACT [EV:0100030] xref: FMA:14274 ! tunica adventitia of artery xref: EV:0100030 ! arterial adventitia intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0000415 ! artery wall relationship: has_part CL:1000306 {source="FMA"} ! fibroblast of tunica adventitia of artery xref: SCTID:113261001 ! Tunica adventitia of artery def: "A tunica adventitia that is part of a artery." [OBOL:automatic] [Term] id: UBERON:0007241 name: tunica adventitia of vein synonym: "tunica externa (adventitia)(venae)" EXACT [FMA:14355] synonym: "venous adventitia" EXACT [EV:0100034] xref: FMA:14355 ! tunica adventitia of vein xref: EV:0100034 ! venous adventitia intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: part_of UBERON:0001638 ! vein xref: SCTID:13202006 ! Tunica adventitia of vein def: "A tunica adventitia that is part of a vein." [OBOL:automatic] [Term] id: UBERON:0005740 name: tunica intima of artery synonym: "tunica interna (intima)(arteriae)" EXACT [FMA:14272] synonym: "arterial intima" EXACT [EV:0100028] xref: FMA:14272 ! Tunica intima of artery xref: EV:0100028 ! arterial intima intersection_of: UBERON:0002523 ! tunica intima intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0000415 ! artery wall xref: galen:IntimaOfArtery xref: SCTID:40022005 ! Tunica intima of artery def: "A tunica intima that is part of a artery." [OBOL:automatic] [Term] id: UBERON:0007242 name: tunica intima of vein synonym: "tunica interna (intima)(venae)" EXACT [FMA:14353] synonym: "venous intima" EXACT [EV:0100032] xref: FMA:14353 ! tunica intima of vein xref: EV:0100032 ! venous intima intersection_of: UBERON:0002523 ! tunica intima intersection_of: part_of UBERON:0001638 ! vein xref: SCTID:2436009 ! Tunica intima of vein def: "A tunica intima that is part of a vein." [OBOL:automatic] [Term] id: UBERON:0007239 name: tunica media of artery synonym: "tunica media (arteriae)" EXACT [FMA:14273] synonym: "arterial media" EXACT [EV:0100029] xref: FMA:14273 ! tunica media of artery xref: EV:0100029 ! arterial media intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0000415 ! artery wall xref: SCTID:84300001 ! Tunica media of artery xref: ncithesaurus:Venous_System_Smooth_Muscle_Tissue ! venous system smooth muscle tissue def: "A tunica media that is part of a artery." [OBOL:automatic] xref: UMLS:C1710627 [Term] id: UBERON:0007243 name: tunica media of vein synonym: "tunica media (venae)" EXACT [FMA:14354] synonym: "venous media" EXACT [EV:0100033] xref: FMA:14354 ! tunica media of vein xref: EV:0100033 ! venous media intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0001638 ! vein xref: SCTID:42049001 ! Tunica media of vein def: "A tunica media that is part of a vein." [OBOL:automatic] [Term] id: UBERON:0004665 name: seminal vesicle muscle layer def: "A portion of muscle tissue that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic] synonym: "muscular coat of seminal gland" EXACT [FMA:19404] synonym: "muscular layer of seminal gland" EXACT [FMA:19404] synonym: "tunica muscularis (Vesicula seminalis)" EXACT [FMA:19404] synonym: "muscle layer of seminal vesicle" EXACT [FMA:19404] xref: FMA:19404 ! Muscle layer of seminal vesicle xref: MA:0002913 ! seminal vesicle muscle layer xref: EMAPA:29773 ! muscle layer of seminal vesicle intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0000998 ! seminal vesicle synonym: "tunica muscularis glandulae vesiculosae" EXACT LATIN [FMA:TA, FMA:19404] [Term] id: UBERON:0004666 name: interventricular septum membranous part synonym: "membranous interventricular septum" RELATED [MA:0002939] synonym: "Membranous interventricular septum" EXACT [FMA:7135] synonym: "Membranous portion of interventricular septum" EXACT [FMA:7135] synonym: "Pars membranacea (septi interventricularis)" EXACT [FMA:7135] synonym: "membranous part of interventricular septum" EXACT [FMA:7135] xref: FMA:7135 ! Membranous part of interventricular septum xref: MA:0002939 ! interventricular septum membranous part xref: VHOG:0000927 ! membranous part interventricular septum xref: EHDAA2:0004596 ! interventricular septum membraneous part xref: EMAPA:18246 ! membranous part is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002094 ! interventricular septum xref: SCTID:278228007 ! Entire membranous portion of interventricular septum synonym: "membranous part interventricular septum" EXACT [VHOG:0000927] [Term] id: UBERON:0004667 name: interventricular septum muscular part def: "A portion of muscle tissue that is part of a interventricular septum [Automatically generated definition]." [OBOL:automatic] synonym: "muscular interventricular septum" RELATED [MA:0002940] synonym: "Muscular interventricular septum" EXACT [FMA:7134] synonym: "Pars muscularis (septi interventricularis)" EXACT [FMA:7134] synonym: "muscular part of interventricular septum" EXACT [FMA:7134] xref: FMA:7134 ! Muscular part of interventricular septum xref: MA:0002940 ! interventricular septum muscular part xref: RETIRED_EHDAA2:0000888 ! interventricular septum muscular part xref: EMAPA:18247 ! muscular part xref: EHDAA:2607 ! muscular part intersection_of: UBERON:0002385 ! muscle tissue intersection_of: part_of UBERON:0002094 ! interventricular septum [Term] id: UBERON:0004671 name: gyrus rectus synonym: "gyrus rectus" EXACT [NIF_GrossAnatomy:birnlex_1103] synonym: "medial part of gyri orbitales" EXACT [FMA:61893] synonym: "rectal gyrus" EXACT [FMA:61893] synonym: "rectus gyrus" EXACT [FMA:61893] synonym: "straight gyrus" EXACT [FMA:61893] xref: FMA:61893 ! straight gyrus xref: NIF_GrossAnatomy:birnlex_1103 ! Gyrus rectus is_a: UBERON:0002791 ! regional part of telencephalon is_a: UBERON:0003022 ! lobe parts of cerebral cortex relationship: part_of UBERON:0001870 ! frontal lobe relationship: part_of UBERON:0001950 ! neocortex xref: SCTID:279206004 ! Entire gyrus rectus [Term] id: UBERON:0004672 name: posterior horn lateral ventricle synonym: "posterior horn lateral ventricle" EXACT [NIF_GrossAnatomy:birnlex_1297] synonym: "posterior horn of lateral ventricle" EXACT [FMA:83700] synonym: "occipital horn of lateral ventricle" EXACT [FMA:83700] synonym: "occipital horn" EXACT [NIF_GrossAnatomy:birnlex_1297] synonym: "posterior horn of the lateral ventricle" EXACT [NIF_GrossAnatomy:birnlex_1297] xref: FMA:83700 ! occipital horn of lateral ventricle xref: NIF_GrossAnatomy:birnlex_1297 ! Posterior horn lateral ventricle is_a: UBERON:0004086 ! brain ventricle relationship: part_of UBERON:0002285 ! telencephalic ventricle synonym: "cornu posterius ventriculi lateralis" EXACT LATIN [FMA:TA, FMA:83700] xref: ncithesaurus:Occipital_Horn_of_the_Lateral_Ventricle ! Occipital Horn of the Lateral Ventricle xref: SCTID:362314009 ! Entire posterior horn of lateral ventricle xref: UMLS:C0152282 [Term] id: UBERON:0004673 name: trigeminal nerve root comment: TODO - check ZFA synonym: "trigeminal nerve root" EXACT [NIF_GrossAnatomy:birnlex_1346] synonym: "trigeminal neural root" EXACT [FMA:52610] synonym: "root of trigeminal nerve" EXACT [FMA:52610] synonym: "root of trigeminal V nerve" EXACT [Obol:cjm] xref: FMA:52610 ! root of trigeminal nerve xref: NIF_GrossAnatomy:birnlex_1346 ! Trigeminal nerve root xref: ZFA:0000192 ! descending trigeminal root is_a: UBERON:0006843 {source="FMA"} ! root of cranial nerve intersection_of: UBERON:0002211 ! nerve root intersection_of: continuous_with UBERON:0001645 ! trigeminal nerve relationship: part_of UBERON:0001895 ! metencephalon xref: SCTID:280185007 ! Root of trigeminal nerve xref: TAO:0000192 ! descending trigeminal root synonym: "descending trigeminal root" RELATED [TAO:0000192] def: "A nerve root that continuous_with a trigeminal nerve." [OBOL:automatic] [Term] id: UBERON:0004674 name: facial nerve root synonym: "facial nerve root" EXACT [NIF_GrossAnatomy:birnlex_1513] synonym: "central part of facial nerve" EXACT [FMA:53418] synonym: "facial nerve fibers" EXACT [FMA:53418] synonym: "facial neural root" EXACT [FMA:53418] synonym: "root of facial nerve" EXACT [FMA:53418] xref: FMA:53418 ! root of facial nerve xref: NIF_GrossAnatomy:birnlex_1513 ! Facial nerve root is_a: UBERON:0006843 {source="FMA"} ! root of cranial nerve intersection_of: UBERON:0002211 ! nerve root intersection_of: continuous_with UBERON:0001647 ! facial nerve relationship: part_of UBERON:0001895 ! metencephalon xref: SCTID:280186008 ! Root of facial nerve def: "A nerve root that continuous_with a facial nerve." [OBOL:automatic] [Term] id: UBERON:0009906 name: root of optic nerve comment: TODO - check. See comments for optic tract. FMA also has medial root. synonym: "root of optic tract" EXACT [FMA:84573] synonym: "optic tract root" EXACT [FMA:84573] synonym: "optic nerve root" EXACT [NIF_GrossAnatomy:birnlex_1328] is_a: UBERON:0006843 {source="FMA"} ! root of cranial nerve intersection_of: UBERON:0002211 ! nerve root intersection_of: continuous_with UBERON:0004904 ! optic nerve xref: FMA:84573 ! root of optic tract xref: NIF_GrossAnatomy:birnlex_1328 ! Optic nerve root def: "A nerve root that continuous_with a nerve connecting eye with brain." [OBOL:automatic] [Term] id: UBERON:0004675 name: hypoglossal nerve root synonym: "hypoglossal nerve root" EXACT [NIF_GrossAnatomy:birnlex_1588] synonym: "central part of hypoglossal nerve" EXACT [FMA:72632] synonym: "hypoglossal nerve fibers" EXACT [FMA:72632] synonym: "root of hypoglossal nerve" EXACT [FMA:72632] synonym: "hypoglossal nerve tract" EXACT [FMA:72632] xref: FMA:72632 ! hypoglossal nerve tract xref: NIF_GrossAnatomy:birnlex_1588 ! Hypoglossal nerve root is_a: UBERON:0006843 {source="FMA"} ! root of cranial nerve intersection_of: UBERON:0002211 ! nerve root intersection_of: continuous_with UBERON:0001650 ! hypoglossal nerve relationship: part_of UBERON:0001896 ! medulla oblongata def: "A nerve root that continuous_with a hypoglossal nerve." [OBOL:automatic] [Term] id: UBERON:0004678 name: apex of spinal cord dorsal horn synonym: "apex of spinal cord dorsal horn" EXACT [NIF_GrossAnatomy:birnlex_2670] synonym: "apex of dorsal gray column" EXACT [FMA:256700] synonym: "apex of dorsal horn of spinal cord" EXACT [FMA:256700] synonym: "apex of posterior horn of spinal cord" EXACT [FMA:256700] synonym: "apex of dorsal gray column of spinal cord" EXACT [FMA:256700] synonym: "apex of spinal cord posterior horn" EXACT [NIF_GrossAnatomy:birnlex_2670] xref: FMA:256700 ! apex of dorsal gray column of spinal cord xref: NIF_GrossAnatomy:birnlex_2670 ! Apex of spinal cord dorsal horn is_a: UBERON:0002315 ! gray matter of spinal cord synonym: "apex cornu posterioris medullae spinalis" EXACT LATIN [FMA:TA, FMA:256700] [Term] id: UBERON:0004680 name: body of fornix def: "The columns (anterior pillars; fornicolumns) of the fornix arch downward in front of the interventricular foramen and behind the anterior commissure, and each descends through the gray substance in the lateral wall of the third ventricle to the base of the brain, where it ends in the corpus mammillare. [WP,unvetted]." [Wikipedia:Columns_of_fornix] synonym: "body of fornix" EXACT [NIF_GrossAnatomy:birnlex_739] synonym: "column of fornix" EXACT [FMA:61968] synonym: "fornix body" EXACT [FMA:61968] synonym: "body of fornix of forebrain" EXACT [FMA:61968] synonym: "columns of fornix" EXACT [Wikipedia:Columns_of_fornix] xref: FMA:61968 ! body of fornix of forebrain xref: NIF_GrossAnatomy:birnlex_739 ! Body of fornix xref: SCTID:369117006 ! Entire columns of fornix xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/21/Gray747.png/200px-Gray747.png is_a: UBERON:0002316 ! white matter of neuraxis is_a: UBERON:0002780 ! regional part of forebrain synonym: "columna fornicis" EXACT LATIN [FMA:TA, FMA:61968] synonym: "columna fornicis" RELATED LATIN [Wikipedia:Columns_of_fornix] xref: http://upload.wikimedia.org/wikipedia/commons/2/21/Gray747.png [Term] id: UBERON:0004682 name: corona radiata def: "For the structure in embryology, see Corona radiata (embryology) In neuroanatomy, the corona radiata is a white matter sheet that continues caudally as the internal capsule and rostrally as the centrum semiovale. This sheet of axons contains both descending and ascending axons that carry nearly all of the neural traffic from and to the cerebral cortex. The corona radiata is associated with the corticospinal tract, the corticopontine tract, and the corticobulbar tract. [WP,unvetted]." [Wikipedia:Corona_radiata] synonym: "corona radiata" EXACT [NIF_GrossAnatomy:nlx_anat_090903] xref: FMA:18661 ! corona radiata xref: NIF_GrossAnatomy:nlx_anat_090903 ! Corona radiata xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/26/Gray745.png/200px-Gray745.png is_a: UBERON:0002316 ! white matter of neuraxis is_a: UBERON:0002791 ! regional part of telencephalon xref: http://upload.wikimedia.org/wikipedia/commons/2/26/Gray745.png [Term] id: UBERON:0004683 name: parasubiculum synonym: "parasubiculum" EXACT [NIF_GrossAnatomy:nlx_anat_091002] synonym: "parasubicular area" EXACT [NIF_GrossAnatomy:nlx_anat_091002] xref: FMA:77604 ! parasubiculum xref: NIF_GrossAnatomy:nlx_anat_091002 ! Parasubiculum xref: ABA:PAR ! Parasubiculum xref: BM:Tel-Cx-PASB ! parasubiculum is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: spatially_disjoint_from UBERON:0002728 {source="ABA"} ! entorhinal area relationship: spatially_disjoint_from UBERON:0001953 {source="ABA"} ! presubiculum relationship: spatially_disjoint_from UBERON:0002191 {source="ABA"} ! subiculum [Term] id: UBERON:0004686 name: gastro-splenic ligament def: "peritoneum connecting the greater curvature of stomach with the hilum of the spleen[umich]. part of the greater omentum; derived from the dorsal mesogastrium in the embryo." [Wikipedia:Gastrosplenic_ligament, http://anatomy.med.umich.edu/gastrointestinal_system/stomach_tables.html] comment: in MA, EMAPA and EHDAA2 this is part of the dorsal mesogastrium. In wikipedia, and the above source, it is derived from the DM. This is a generic ligament in MA, we infer this and assert that this is a nonskeletal ligament synonym: "ligamentum gastrosplenicum" EXACT [Wikipedia:Gastrosplenic_ligament] synonym: "gastrolienal ligament" EXACT [FMA:16517] synonym: "gastrosplenc ligament" EXACT [FMA:16517] synonym: "gastrosplenic ligament" EXACT [FMA:16517] xref: FMA:16517 ! Gastrosplenic ligament xref: MA:0001619 ! gastro-splenic ligament xref: VHOG:0000354 ! gastro-splenic ligament xref: EHDAA2:0000702 ! gastrosplenic ligament xref: EMAPA:18285 ! gastro-splenic ligament of dorsal mesogastrium of mesentery of stomach of foregut xref: EMAPA:18905 ! gastro-splenic ligament of greater omentum of dorsal mesogastrium of mesentery of stomach of gut xref: EHDAA:9160 ! gastrosplenic ligament xref: http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray1039.png is_a: UBERON:0008845 {source="MA-propagated"} ! nonskeletal ligament relationship: connects UBERON:0000945 ! stomach relationship: connects UBERON:0002106 ! spleen relationship: attaches_to UBERON:0001248 ! hilum of spleen relationship: part_of UBERON:0005448 {source="FMA", source="Wikipedia"} ! greater omentum relationship: develops_from UBERON:0005602 {source="MA-modified", source="Wikipedia"} ! dorsal mesogastrium xref: SCTID:260636005 ! Entire gastrosplenic ligament property_value: external_definition "Mesenteric fold extending from the greater curvature of the stomach to the spleen. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000354", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0012471 name: hepatogastric ligament def: "Ligament extending between the liver and stomach" [Wikipedia:Hepatogastric_ligament] synonym: "ligamentum hepatogastricum" EXACT LATIN [Wikipedia:Hepatogastric_ligament] synonym: "gastrohepatic ligament" EXACT [FMA:16520] synonym: "gastro-hepatic ligament" EXACT [] synonym: "hepato-gastric ligament" EXACT [] is_a: UBERON:0008845 ! nonskeletal ligament relationship: connects UBERON:0000945 ! stomach relationship: connects UBERON:0002107 ! liver relationship: part_of UBERON:0002399 {source="FMA"} ! lesser omentum relationship: develops_from UBERON:0005602 ! dorsal mesogastrium xref: FMA:16520 ! hepatogastric ligament xref: ncithesaurus:Hepatogastric_Ligament ! hepatogastric ligament xref: SCTID:260825001 ! Entire gastrohepatic ligament xref: UMLS:C0230232 [Term] id: UBERON:0012472 name: hepatoduodenal ligament def: "The hepatoduodenal ligament is the portion of the lesser omentum extending between the porta hepatis of the liver and the superior part of the duodenum." [Wikipedia:Hepatoduodenal_ligament] synonym: "ligamentum hepatoduodenale" EXACT [Wikipedia:Hepatoduodenal_ligament] is_a: UBERON:0008845 ! nonskeletal ligament relationship: connects UBERON:0002107 ! liver relationship: connects UBERON:0002114 ! duodenum relationship: part_of UBERON:0002399 {source="FMA"} ! lesser omentum xref: FMA:16521 ! hepatoduodenal ligament xref: SCTID:362706000 ! Entire hepatoduodenal ligament [Term] id: UBERON:0004687 name: lieno-renal ligament def: "peritoneum that attaches the spleen to the posterior abdominal wall over the left kidney. develops from the dorsal mesogastrium of the embryo[umich]" [Wikipedia:Splenorenal_ligament, http://anatomy.med.umich.edu/gastrointestinal_system/peritoneum_tables.html] comment: Multiple sources support greater omentum assignment. E.g. http://medical-dictionary.thefreedictionary.com/splenorenal+ligament. We change the MA part_of assignment to develops_from synonym: "lienorenal ligament" EXACT [FMA:16522] synonym: "ligamentum splenorenale (lienorenale, phrenicosplenicum)" EXACT [FMA:16522] synonym: "phrenicolienal ligament" EXACT [FMA:16522] synonym: "splenicorenal ligament" EXACT [FMA:16522] synonym: "splenorenal ligament" EXACT [FMA:16522] synonym: "ligamentum lienorenale" EXACT LATIN [FMA:TA, FMA:16522] xref: FMA:16522 ! Splenorenal ligament xref: MA:0001620 ! lieno-renal ligament xref: EMAPA:18286 ! lieno-renal ligament of dorsal mesogastrium of mesentery of stomach of foregut xref: EMAPA:18906 ! lieno-renal ligament of greater omentum of dorsal mesogastrium of mesentery of stomach of gut xref: EHDAA2:0004572 ! lienorenal ligament is_a: UBERON:0008845 {source="MA-propagated"} ! nonskeletal ligament relationship: attaches_to UBERON:0002106 ! spleen relationship: attaches_to UBERON:0002113 ! kidney relationship: part_of UBERON:0005448 {source="FMA"} ! greater omentum relationship: develops_from UBERON:0005602 {source="MA-modified"} ! dorsal mesogastrium [Term] id: UBERON:0004688 name: costo-cervical trunk def: "The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]." [Wikipedia:Costocervical_trunk] synonym: "trunk of costocervical artery" EXACT [FMA:10636] synonym: "costocervical trunk" EXACT [FMA:10636] xref: FMA:10636 ! Costocervical trunk xref: MA:0001939 ! costo-cervical trunk xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b3/Costocervical_trunk_with_branches.png/200px-Costocervical_trunk_with_branches.png is_a: UBERON:0001637 ! artery xref: SCTID:244225009 ! Entire costocervical trunk synonym: "truncus costocervicalis" RELATED LATIN [Wikipedia:Costocervical_trunk] xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/Costocervical_trunk_with_branches.png [Term] id: UBERON:0004689 name: naso-frontal vein synonym: "nasofrontal vein" EXACT [FMA:51729] xref: FMA:51729 ! Nasofrontal vein xref: MA:0002182 ! naso-frontal vein is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0005486 {source="FMA/obol"} ! venous dural sinus relationship: tributary_of UBERON:0003712 {source="FMA/obol"} ! cavernous sinus xref: SCTID:44840002 ! Entire nasofrontal vein [Term] id: UBERON:0012304 name: nasal diverticulum def: "Caudally blind-ending cutaneous pouch lined with skin that occupies the nasoincisive notch. It's ventral and medial walls is formed by the alar fold. It's lateral wall is formed by the external nares and it's dorsal wall is formed by the straight fold. Lined by pigmented predominantly hairless skin. It has an external opening located on the dorsolateral aspect of the "true nostril". When the horse is exercising, obliteration of the nasal diverticulum greatly widens the nostrils increasing air intake[MURDOCH]." [ISBN:3899930983, MURDOCH:1367] synonym: "false nostril" RELATED [] synonym: "nasal trumpet" RELATED [ISBN:3899930983] synonym: "soft nose" RELATED [ISBN:3899930983] is_a: UBERON:0000014 ! zone of skin relationship: part_of UBERON:0005928 ! external naris [Term] id: UBERON:0004692 name: external naris epithelium def: "An epithelium that is part of a naris [Automatically generated definition]." [OBOL:automatic] xref: MA:0001321 ! external naris epithelium xref: EMAPA:18596 ! epithelium of external of naris intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005928 ! external naris [Term] id: UBERON:0004693 name: Peyer's patch epithelium def: "An epithelium that is part of a Peyer' s patch [Automatically generated definition]." [OBOL:automatic] synonym: "peyer's patch epithelium" EXACT [MA:0000731] xref: MA:0000731 ! peyer's patch epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001211 ! part_of Peyer's patch [Term] id: UBERON:0004694 name: harderian gland epithelium def: "An epithelium that is part of a Harderian gland [Automatically generated definition]." [OBOL:automatic] xref: MA:0001248 ! harderian gland epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004187 ! Harderian gland [Term] id: UBERON:0004695 name: arterial system smooth muscle def: "A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]." [OBOL:automatic] xref: MA:0000704 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0004572 ! part_of arterial system [Term] id: UBERON:0004696 name: venous system smooth muscle def: "A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]." [OBOL:automatic] xref: MA:0000715 ! venous system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0004582 ! part_of venous system relationship: part_of UBERON:0004237 ! blood vessel smooth muscle [Term] id: UBERON:0004698 name: vena cava endothelium def: "An endothelium that is part of a vena cava [Automatically generated definition]." [OBOL:automatic] xref: MA:0000713 ! vena cava endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004087 ! part_of vena cava xref: ncithesaurus:Vena_Cava_Endothelium ! Vena Cava Endothelium xref: UMLS:C1710623 [Term] id: UBERON:0004699 name: outflow tract endothelium def: "An endothelium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] xref: MA:0000490 ! outflow tract endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004145 ! part_of outflow tract xref: VHOG:0001524 ! outflow tract endothelium property_value: homology_notes "It is assumed that during evolution, a circulatory system composed of the heart and endothelial tubular system first formed in vertebrates, medial smooth muscle then appeared for regulation of the system, and innervation of the muscle tissue took place. This sequence of development assumed for phylogenesis is actually realized in the ontogenetic processes.[well established][VHOG]" xsd:string {external_class="VHOG:0001524", ontology="VHOG", source="DOI:10.1254/jjp.87.253 Shigei T\, Tsuru H\, Ishikawa N\, Yoshioka K\, Absence of endothelium in invertebrate blood vessels: significance of endothelium and sympathetic nerve/medial smooth muscle in the vertebrate vascular system. Japanese Journal of Pharmacology (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0004701 name: venous system endothelium def: "An endothelium that is part of a venous system [Automatically generated definition]." [OBOL:automatic] xref: MA:0000714 ! venous system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004582 ! part_of venous system xref: ncithesaurus:Venous_System_Endothelium ! Venous System Endothelium xref: UMLS:C1710626 [Term] id: UBERON:0004702 name: respiratory system blood vessel endothelium def: "A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: MA:0001805 ! respiratory system blood vessel endothelium intersection_of: UBERON:0004638 ! blood vessel endothelium intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003504 ! respiratory system blood vessel [Term] id: UBERON:0013479 name: lung endothelium def: "A blood vessel endothelium that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "respiratory endothelium" RELATED [BTO:0004128] intersection_of: UBERON:0004638 ! blood vessel endothelium intersection_of: part_of UBERON:0002048 ! lung xref: BTO:0004128 ! lung endothelium xref: CALOHA:TS-0573 ! Lung endothelium [Term] id: UBERON:0008324 ! erectile tissue name: erectile tissue is_a: UBERON:0000479 ! tissue [Term] id: UBERON:0006609 ! corpus cavernosum name: corpus cavernosum def: "." [Wikipedia:Corpus_cavernosum] is_a: UBERON:0008324 ! erectile tissue [Term] id: UBERON:0004713 name: corpus cavernosum penis def: "One of the columns of erectile tissue forming the dorsum and sides of the penis." [BTO:0002019, Wikipedia:Corpus_cavernosum_penis] synonym: "cavernous body of penis" RELATED [BTO:0002019] synonym: "penile corpus cavernosum" RELATED [BTO:0002019] synonym: "spongy body of male urethra" RELATED [BTO:0002019] synonym: "spongy body of penis" RELATED [BTO:0002019] synonym: "corpus cavernosum of penis" EXACT [FMA:19618] synonym: "corpus cavernosum" BROAD [BTO:0002019] synonym: "corpus spongiosum penis" RELATED INCONSISTENT [BTO:0002019] synonym: "penis erectile tissue" BROAD [MA:0001743] xref: Wikipedia:Corpus_cavernosum_penis ! corpus cavernosum penis xref: BTO:0002019 ! corpus cavernosum penis xref: FMA:19618 ! Corpus cavernosum of penis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/f/f6/Gray1155.png/200px-Gray1155.png xref: EMAPA:29856 ! corpus spongiosum of glans penis of penis (also: UBERON:0011183 'corpus spongiosum of penis') xref: EMAPA:29850 ! corpus spongiosum of crus penis (also: UBERON:0011183 'corpus spongiosum of penis') xref: MA:0001743 ! penis erectile tissue xref: SCTID:245468004 ! Entire corpus cavernosum intersection_of: UBERON:0006609 ! corpus cavernosum intersection_of: part_of UBERON:0000989 ! penis relationship: has_function_in GO:0043084 ! penile erection xref: ncithesaurus:Penis_Erectile_Tissue ! Penis Erectile Tissue xref: ncithesaurus:Corpora_Cavernosa ! corpora cavernosa synonym: "corpus cavernosum penis" RELATED LATIN [Wikipedia:Corpus_cavernosum_penis] xref: http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray1155.png xref: UMLS:C0227937 xref: UMLS:C1709494 [Term] id: UBERON:0006608 ! corpus cavernosum clitoridis name: corpus cavernosum clitoridis def: "The corpus cavernosum clitoridis is one of a pair of sponge-like regions of erectile tissue which contain most of the blood in the clitoris during clitoral erection. This is homologous to the corpus cavernosum penis in the male; the body of the clitoris contains erectile tissue in a pair of corpora cavernosa (literally \"cave-like bodies\"), with a recognisably similar structure." [Wikipedia:Corpus_cavernosum_of_clitoris] synonym: "cavernous body of clitoris" RELATED [BTO:0002018] synonym: "clitoral corpus cavernosum" RELATED [BTO:0002018] synonym: "corpus cavernosum" RELATED [BTO:0002018] xref: BTO:0002018 ! corpus cavernosum clitoridis xref: FMA:20172 ! corpus cavernosum of clitoris xref: SCTID:16657007 ! Corpus cavernosum of clitoris intersection_of: UBERON:0006609 ! corpus cavernosum intersection_of: part_of UBERON:0002411 ! clitoris synonym: "corpus cavernosum clitoridis" RELATED LATIN [Wikipedia:Corpus_cavernosum_of_clitoris] xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Clitoris_inner_anatomy.gif synonym: "corpus cavernosum of clitoris" EXACT [FMA:20172] [Term] id: UBERON:0011183 name: corpus spongiosum of penis def: "Corpus spongiosum (also known as corpus cavernosum urethrae in older texts) is the mass of spongy tissue surrounding the male urethra within the penis." [Wikipedia:Corpus_spongiosum_penis] comment: Function notes: The function of the corpus spongiosum in erection is to prevent the urethra from pinching closed, thereby maintaining the urethra as a viable channel for ejaculation. To do this, the corpus spongiosum remains pliable during erection while the corpora cavernosum penis becomes engorged with blood.[WP] synonym: "corpus cavernosum urethra" RELATED DEPRECATED [Wikipedia:Corpus_spongiosum_penis] synonym: "corpus cavernosum urethrae" RELATED DEPRECATED [Wikipedia:Corpus_spongiosum_penis] synonym: "corpus spongiosum" RELATED [Wikipedia:Corpus_spongiosum_penis] synonym: "spongiose body of penis" EXACT [FMA:19617] is_a: UBERON:0008324 ! erectile tissue relationship: part_of UBERON:0000989 ! penis relationship: surrounds UBERON:0000057 ! urethra relationship: has_function_in GO:0043084 ! penile erection xref: FMA:19617 ! corpus spongiosum of penis xref: EMAPA:29850 ! corpus spongiosum (also: UBERON:0004713 'corpus cavernosum penis') xref: EMAPA:29856 ! corpus spongiosum (also: UBERON:0004713 'corpus cavernosum penis') xref: ncithesaurus:Corpus_Spongiosum ! corpus spongiosum xref: http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray1155.png xref: SCTID:279712008 ! Entire corpus spongiosum xref: UMLS:C1522442 [Term] id: UBERON:0004714 ! septum pellucidum name: septum pellucidum def: "The septum pellucidum is made up of two thin sheets of mostly glial-like elements that abut each other in the midline and have a potential space between them. Those sheets also separate the left and right lateral ventricles from each other. At the base of the sheets rostrally, however, are the septal nuclei, which are important components of the limbic system.a thin, triangular, vertical membrane separating the lateral ventricles of the brain. It separates the anterior horn of the left and right lateral ventricles. It runs as a sheet from the corpus callosum down to the fornix. When the hemispheres are cut apart, the septum remains on one hemisphere, usually the left. The septum pellucidum is implicated in pleasure, mood, rage, sexual gratification and more. Lesions of the septum lead to sham rage. Stimulation of the medial forebrain bundle (primary efferent of the septum) restores normal behavior." [Wikipedia:Septum_pellucidum, BTO:0003448] synonym: "pellucidum" RELATED [BTO:0003448] synonym: "septum lucidum" RELATED [BTO:0003448] synonym: "supracommissural septum" EXACT [FMA:61844] xref: Wikipedia:Septum_pellucidum ! septum pellucidum xref: BTO:0003448 ! septum pellucidum xref: FMA:61844 ! Septum pellucidum xref: MA:0002979 ! septum pellucidum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/4/4d/Gray732.png/200px-Gray732.png xref: MESH:A08.186.211.276.814 ! septum pellucidum is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0002285 ! telencephalic ventricle relationship: part_of UBERON:0000446 ! septum of telencephalon xref: ncithesaurus:Septum_Pellucidum ! Septum Pellucidum xref: SCTID:362313003 ! Entire septum pellucidum xref: NIF_GrossAnatomy:birnlex_1315 ! Septal pellucidum xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray732.png xref: UMLS:C0036700 [Term] id: UBERON:0006444 ! annulus fibrosus name: annulus fibrosus def: "A ring of fibrous or fibrocartilaginous tissue (as of an intervertebral disk or surrounding an orifice of the heart)." [BTO:0003627] synonym: "fibrous ring" RELATED [BTO:0003627] synonym: "anulus fibrosus" EXACT [FMA:76704] subset: grouping_class xref: BTO:0003627 ! annulus fibrosus xref: FMA:76704 ! anulus fibrosus is_a: UBERON:0001995 ! fibrocartilage [Term] id: UBERON:0006008 ! fibrous ring of heart name: fibrous ring of heart def: "The right and left fibrous rings of heart (anulus fibrosus cordis) surround the atrioventricular and arterial orifices, and are stronger upon the left than on the right side of the heart. The right fibrous ring is known as the anulus fibrosus dexter cordis, and the left is known as the anulus fibrosus sinister cordis. The atrioventricular rings serve for the attachment of the muscular fibers of the atria and ventricles, and for the attachment of the bicuspid and tricuspid valves. The left atrioventricular ring is closely connected, by its right margin, with the aortic arterial ring; between these and the right atrioventricular ring is a triangular mass of fibrous tissue, the trigonum fibrosum, which represents the os cordis seen in the heart of some of the larger animals, as the ox and elephant. Lastly, there is the tendinous band, already referred to, the posterior surface of the conus arteriosus. The fibrous rings surrounding the arterial orifices serve for the attachment of the great vessels and semilunar valves, they are known as The aortic annulus. Each ring receives, by its ventricular margin, the attachment of some of the muscular fibers of the ventricles; its opposite margin presents three deep semicircular notches, to which the middle coat of the artery is firmly fixed. The attachment of the artery to its fibrous ring is strengthened by the external coat and serous membrane externally, and by the endocardium internally. From the margins of the semicircular notches the fibrous structure of the ring is continued into the segments of the valves. The middle coat of the artery in this situation is thin, and the vessel is dilated to form the sinuses of the aorta and pulmonary artery." [Wikipedia:Fibrous_rings_of_heart] comment: todo - compare with ZFA atrioventricular ring, part of the conduction system synonym: "annulus fibrosus cordis" RELATED LATIN [Wikipedia:Fibrous_rings_of_heart] synonym: "anulus fibrosus cordis" RELATED [Wikipedia:Fibrous_rings_of_heart] synonym: "aortic annulus" RELATED [Wikipedia:Fibrous_rings_of_heart] synonym: "fibrous ring of heart" RELATED [Wikipedia:Fibrous_rings_of_heart] synonym: "anulus fibrosus of heart" EXACT [FMA:9497] synonym: "coronary tendon" RELATED [BTO:0003628] synonym: "Lower's ring" RELATED [BTO:0003628] synonym: "atrioventricular ring" RELATED [BTO:0003628] xref: FMA:9497 ! fibrous ring of heart xref: BTO:0003628 ! annulus fibrosus cordis intersection_of: UBERON:0006444 ! annulus fibrosus intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0004719 name: arcuate vein def: "The arcuate vein is a vessel of the renal circulation. It is located at the border of the renal cortex and renal medulla." [Wikipedia:Arcuate_vein] synonym: "arcuate veins" RELATED [Wikipedia:Arcuate_vein] xref: MA:0002593 ! arcuate vein xref: Wikipedia:Arcuate_vein ! arcuate vein xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Kidney_PioM.png/200px-Kidney_PioM.png xref: EMAPA:28221 ! arcuate vein is_a: UBERON:0003517 ! kidney blood vessel synonym: "venae arcuatae renis" RELATED LATIN [Wikipedia:Arcuate_vein] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png [Term] id: UBERON:0004721 name: crista ampullaris def: "The crista ampullaris is the sensory organ of rotation located in the semicircular canal of the inner ear. The function of the crista ampullaris is to sense angular acceleration and deceleration." [Wikipedia:Crista_ampullaris] synonym: "cristae ampullares" RELATED [Wikipedia:Crista_ampullaris] synonym: "ampullary crest" RELATED [MA:0002771] synonym: "ampullary crest of semicircular duct" EXACT [FMA:77714] xref: MA:0002771 ! crista ampullaris xref: Wikipedia:Crista_ampullaris ! crista ampullaris xref: FMA:77714 ! Ampullary crest of semicircular duct is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0004043 {source="MA"} ! semicircular canal ampulla xref: ncithesaurus:Ampullary_Crest ! Ampullary Crest xref: SCTID:368953000 ! Entire crista ampullaris subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/e/ec/Semicircular_canal_-_ampulla.png xref: UMLS:C0229465 [Term] id: UBERON:0006935 ! crista ampullaris neuroepithelium name: crista ampullaris neuroepithelium synonym: "ampullary crest neuroepithelium" RELATED [MA:0002870] synonym: "epithelium of crista of ampulla of semicircular duct of membranous labyrinth" EXACT [FMA:75636] xref: MA:0002870 ! crista ampullaris neuroepithelium xref: FMA:75636 ! epithelium of crista of ampulla of semicircular duct of membranous labyrinth is_a: UBERON:0006932 {source="FMA"} ! vestibular epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004721 ! crista ampullaris relationship: part_of UBERON:0004721 {source="MA"} ! crista ampullaris relationship: has_part CL:0002316 {source="FMA"} ! supporting cell of vestibular epithelium def: "An epithelium that is part of a crista ampullaris." [OBOL:automatic] [Term] id: UBERON:0007274 name: crista of ampulla of anterior semicircular duct of membranous laybrinth comment: todo - unvetted subset: vertebrate_core synonym: "anterior crista ampullaris" EXACT [ZFA:0000619] synonym: "anterior cristae" EXACT PLURAL [ZFA:0000619] synonym: "anterior semicircular canal sensory patch" EXACT [ZFA:0000619] synonym: "anterior semicircular canal sensory patches" EXACT PLURAL [ZFA:0000619] synonym: "rostral crista" EXACT [ZFA:0000619] xref: FMA:75610 ! crista of ampulla of anterior semicircular duct of membranous laybrinth xref: ZFA:0000619 ! anterior crista intersection_of: UBERON:0006935 ! crista ampullaris neuroepithelium intersection_of: part_of UBERON:0001857 ! anterior semicircular duct xref: XAO:0004137 ! anterior crista xref: TAO:0000619 ! anterior crista property_value: external_definition "Patches of thickened, pseudostratified epithelium of the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. Each patch has its own charcteristic shape and polarity pattern. (See Anatomical Atlas entry for sensory patches of the ear by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000619", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "anterior crista" RELATED [TAO:0000619] synonym: "AC" RELATED [TAO:0000619] synonym: "sensory patches" RELATED [TAO:0000619] def: "A crista ampullaris neuroepithelium that is part of a anterior semicircular duct." [OBOL:automatic] [Term] id: UBERON:0007275 name: crista of ampulla of posterior semicircular duct of membranous laybrinth comment: todo - unvetted subset: vertebrate_core synonym: "posterior crista ampullaris" EXACT [ZFA:0000566] synonym: "posterior cristae" EXACT PLURAL [ZFA:0000566] synonym: "posterior semicircular canal sensory patch" EXACT [ZFA:0000566] synonym: "posterior semicircular canal sensory patches" EXACT PLURAL [ZFA:0000566] synonym: "caudal crista" EXACT [ZFA:0000566] xref: FMA:75611 ! crista of ampulla of posterior semicircular duct of membranous laybrinth xref: ZFA:0000566 ! posterior crista intersection_of: UBERON:0006935 ! crista ampullaris neuroepithelium intersection_of: part_of UBERON:0001858 ! posterior semicircular duct xref: XAO:0004133 ! posterior crista xref: TAO:0000566 ! posterior crista property_value: external_definition "Patches of thickened, pseudostratified epithelium of the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. Each patch has its own charcteristic shape and polarity pattern. (See Anatomical Atlas entry for sensory patches of the ear by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000566", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "posterior crista" RELATED [TAO:0000566] synonym: "PC" RELATED [TAO:0000566] synonym: "sensory patches" RELATED [TAO:0000566] def: "A crista ampullaris neuroepithelium that is part of a posterior semicircular duct." [OBOL:automatic] [Term] id: UBERON:0007276 name: crista of ampulla of lateral semicircular duct of membranous laybrinth comment: todo - unvetted subset: vertebrate_core synonym: "lateral crista ampullaris" EXACT [ZFA:0000166] synonym: "lateral cristae" EXACT PLURAL [ZFA:0000166] synonym: "lateral semicircular canal sensory patch" EXACT [ZFA:0000166] synonym: "lateral semicircular canal sensory patches" EXACT PLURAL [ZFA:0000166] xref: FMA:75612 ! crista of ampulla of lateral semicircular duct of membranous laybrinth xref: ZFA:0000166 ! lateral crista intersection_of: UBERON:0006935 ! crista ampullaris neuroepithelium intersection_of: part_of UBERON:0001859 ! lateral semicircular duct xref: TAO:0000166 ! lateral crista property_value: external_definition "Patches of thickened, pseudostratified epithelium of the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. Each patch has its own charcteristic shape and polarity pattern. (See Anatomical Atlas entry for sensory patches of the ear by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000166", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "lateral crista" RELATED [TAO:0000166] synonym: "LC" RELATED [TAO:0000166] synonym: "sensory patches" RELATED [TAO:0000166] def: "A crista ampullaris neuroepithelium that is part of a lateral semicircular duct." [OBOL:automatic] [Term] id: UBERON:0004722 ! deep cervical lymph node name: deep cervical lymph node def: "The deep cervical lymph nodes are a group of cervical lymph nodes found near the internal jugular vein. They can be divided into upper and lower groups, or superior and inferior groups. Alternatively, they can be divided into deep anterior cervical lymph nodes and deep lateral cervical lymph nodes. They can also be divided into three groups: superior deep jugular, middle deep jugular, and 'inferior deep jugular'." [Wikipedia:Deep_cervical_lymph_nodes] synonym: "lower jugular nodes" RELATED [Wikipedia:Deep_cervical_lymph_nodes] synonym: "middle jugular nodes" RELATED [Wikipedia:Deep_cervical_lymph_nodes] synonym: "upper jugular nodes" RELATED [Wikipedia:Deep_cervical_lymph_nodes] xref: MA:0002885 ! deep cervical lymph node xref: Wikipedia:Deep_cervical_lymph_nodes ! deep cervical lymph nodes xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b6/Illu_lymph_chain02.jpg/200px-Illu_lymph_chain02.jpg is_a: UBERON:0002429 ! cervical lymph node xref: ncithesaurus:Deep_Cervical_Lymph_Node ! Deep Cervical Lymph Node xref: SCTID:279145002 ! Deep cervical lymph node xref: http://upload.wikimedia.org/wikipedia/commons/b/b6/Illu_lymph_chain02.jpg xref: UMLS:C0458298 [Term] id: UBERON:0004870 ! superficial cervical lymph node name: superficial cervical lymph node def: "A group of nodes lying along the external jugular vein; they drain the skin and superficial structures over the region of the sternocleidomastoid muscle and anterior cervical regions. Efferent vessels drain to the deep cervical lymph nodes. Lymph nodes can be further subdivided into anterior and lateral groupings." [ref:Stedmans, CL:tm, Wikipedia:Superficial_cervical_lymph_nodes] synonym: "prescapular lymph node" RELATED [CL:tm] xref: MA:0002886 ! superficial cervical lymph node is_a: UBERON:0002429 ! cervical lymph node is_a: UBERON:0003968 {source="CL:tm"} ! peripheral lymph node xref: ncithesaurus:Superficial_Cervical_Lymph_Node ! Superficial Cervical Lymph Node xref: SCTID:279144003 ! Superficial cervical lymph node synonym: "nodi lymphoidei cervicales" RELATED LATIN [Wikipedia:Superficial_cervical_lymph_nodes] xref: http://upload.wikimedia.org/wikipedia/commons/4/4e/Illu_quiz_hn_03.jpg xref: UMLS:C0458297 [Term] id: UBERON:0012306 name: lateral cervical lymph node synonym: "lateral cervical node" EXACT [FMA:61232] is_a: UBERON:0002429 {source="FMA"} ! cervical lymph node xref: FMA:61232 ! lateral cervical lymph node xref: SCTID:167763000 ! Entire lateral cervical lymph node [Term] id: UBERON:0012307 name: anterior cervical lymph node synonym: "anterior cervical node" EXACT [] is_a: UBERON:0002429 {source="FMA"} ! cervical lymph node xref: FMA:61230 ! anterior cervical lymph node xref: SCTID:168259009 ! Entire anterior cervical lymph node [Term] id: UBERON:0012308 name: superficial lateral cervical lymph node def: "The superficial lateral cervical lymph nodes are found in proximity to the external jugular vein." [Wikipedia:Superficial_lateral_cervical_lymph_nodes] synonym: "superficial lateral cervical node" EXACT [FMA:12769] is_a: UBERON:0012306 {source="FMA"} ! lateral cervical lymph node is_a: UBERON:0004870 ! superficial cervical lymph node xref: FMA:12769 ! superficial lateral cervical lymph node xref: SCTID:50679006 ! Entire superficial lateral cervical lymph node [Term] id: UBERON:0012309 name: superficial anterior cervical lymph node def: "The superficial anterior cervical lymph nodes are found in proximity to the anterior jugular vein." [Wikipedia:Superficial_anterior_cervical_lymph_nodes] synonym: "anterior jugular lymph node" EXACT [FMA:12776] is_a: UBERON:0012307 {source="FMA"} ! anterior cervical lymph node is_a: UBERON:0004870 ! superficial cervical lymph node xref: FMA:12776 ! superficial anterior cervical lymph node xref: SCTID:22993006 ! Entire superficial anterior cervical lymph node [Term] id: UBERON:0012310 name: deep lateral cervical lymph node def: "The deep lateral cervical lymph nodes are found near the upper part of the internal jugular vein in the neck, lateral or posterior to the carotid sheath." [Wikipedia:Deep_lateral_cervical_lymph_nodes] synonym: "deep lateral cervical node" EXACT [FMA:12770] is_a: UBERON:0012306 {source="FMA"} ! lateral cervical lymph node is_a: UBERON:0004722 ! deep cervical lymph node xref: FMA:12770 ! deep lateral cervical lymph node xref: SCTID:61755005 ! Entire deep lateral cervical lymph node [Term] id: UBERON:0012311 name: deep anterior cervical lymph node def: "The deep anterior cervical lymph nodes are found near the middle cricothyroid ligament and the trachea." [Wikipedia:Deep_anterior_cervical_lymph_nodes] is_a: UBERON:0012307 {source="FMA"} ! anterior cervical lymph node is_a: UBERON:0004722 ! deep cervical lymph node xref: FMA:12779 ! deep anterior cervical lymph node xref: SCTID:52363008 ! Entire deep anterior cervical lymph node [Term] id: UBERON:0009887 name: interlobar vein def: "The interlobar veins are veins of the renal circulation which drain the renal lobes." [Wikipedia:Interlobar_veins] comment: FMA only has the set term synonym: "interlobar vein of kidney" EXACT [FMA:71631] synonym: "venae interlobares renis" EXACT PLURAL [FMA:TA] xref: FMA:71631 ! set of interlobar veins of kidney is_a: UBERON:0001638 ! vein disjoint_from: UBERON:0005168 ! interlobular vein synonym: "venae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_veins] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png synonym: "set of interlobar veins of kidney" RELATED [FMA:71631] synonym: "interlobar veins of kidney" RELATED [FMA:71631] [Term] id: UBERON:0009885 name: interlobar artery def: "One of a set of curved arteries at the corticomedullary border of the kidney that arise from the interlobar arteries and give rise to the interlobular arteries." [Wikipedia:Interlobar_arteries, MP:0011315] comment: FMA only has the set term synonym: "renal interlobar artery" EXACT [MP:0011355] synonym: "kidney interlobar artery" EXACT [] synonym: "arteriae interlobares renis" EXACT PLURAL [FMA:TA] synonym: "interlobar artery of kidney" EXACT [FMA:71637] xref: FMA:71637 ! set of interlobar arteries of kidney is_a: UBERON:0001637 ! artery disjoint_from: UBERON:0004723 {source="Wikipedia:Renal_circulation"} ! interlobular artery synonym: "arteriae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_arteries] xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png xref: SCTID:62802007 ! Entire interlobar artery of kidney synonym: "set of interlobar arteries of kidney" RELATED [FMA:71637] synonym: "interlobar arteries of kidney" RELATED [FMA:71637] [Term] id: UBERON:0004723 ! interlobular artery name: interlobular artery def: "the branches of the arcuate arteries of the kidney that radiate outward throught the renal columns and supply the glomeruli[MP]. The first set of renal bloodvessels, the interlobular arteries (or cortical radiate arteries, or cortical radial arteries), are given off at right angles from the side of the arcuate arteries looking toward the cortical substance, and pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form what are called end-arteries. In their outward course they give off lateral branches; these are the afferent vessels for the renal corpuscles; they enter the capsule, and end in the glomerulus. From each tuft the corresponding efferent vessel arises, and, having made its egress from the capsule near to the point where the afferent vessel enters, breaks up into a number of branches, which form a dense plexus within Bowman's capsule." [Wikipedia:Interlobular_arteries, MP:0011316] synonym: "cortical radial arteries" RELATED [Wikipedia:Interlobular_arteries] synonym: "interlobular" RELATED [Wikipedia:Interlobular_arteries] synonym: "kidney interlobular artery" EXACT [MP:0011316] xref: MA:0002584 ! interlobular artery xref: Wikipedia:Interlobular_arteries ! interlobular arteries xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/27/Gray1128.png/200px-Gray1128.png xref: EMAPA:28212 ! interlobular artery xref: FMA:70498 ! interlobular renal artery is_a: UBERON:0003644 ! kidney arterial blood vessel xref: ncithesaurus:Interlobular_Artery ! Interlobular Artery synonym: "arteriae corticales radiatae, arteriae interlobulares renis" RELATED LATIN [Wikipedia:Interlobular_arteries] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray1128.png xref: SCTID:76147008 ! Entire interlobular artery of kidney synonym: "interlobular renal artery" EXACT [FMA:70498] xref: UMLS:C1512856 [Term] id: UBERON:0004724 name: medial palpebral ligament def: "The medial palpebral ligament (tendo oculi), about 4 mm. in length and 2 mm. in breadth, is attached to the frontal process of the maxilla in front of the lacrimal groove. Crossing the lacrimal sac, it divides into two parts, upper and lower, each attached to the medial end of the corresponding tarsus. As the ligament crosses the lacrimal sac, a strong aponeurotic is given off from its posterior surface; this expands over the sac, and is attached to the posterior lacrimal crest." [Wikipedia:Medial_palpebral_ligament] xref: MA:0001258 ! medial palpebral ligament xref: Wikipedia:Medial_palpebral_ligament ! medial palpebral ligament xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Gray894.png/200px-Gray894.png is_a: UBERON:0000211 ! ligament relationship: part_of UBERON:0004772 ! eyelid tarsus xref: ncithesaurus:Medial_Palpebral_Ligament ! Medial Palpebral Ligament xref: SCTID:280578002 ! Entire medial palpebral ligament synonym: "l. palpebrale mediale" RELATED LATIN [Wikipedia:Medial_palpebral_ligament] xref: http://upload.wikimedia.org/wikipedia/commons/6/6f/Gray894.png xref: UMLS:C0229251 [Term] id: UBERON:0002590 name: prepyriform area synonym: "lateral olfactory gyrus" EXACT [FMA:62484] synonym: "piriform cortex (price)" EXACT [] synonym: "prepiriform cortex" EXACT [FMA:62484] synonym: "prepyriform cortex" EXACT [FMA:62484] synonym: "(pre-)piriform cortex" EXACT [NIF_GrossAnatomy:birnlex_1097] synonym: "piriform olfactory cortex" EXACT [NIF_GrossAnatomy:birnlex_1097] synonym: "pyriform area" EXACT [NIF_GrossAnatomy:birnlex_1097] xref: FMA:62484 ! Prepyriform area xref: NIF_GrossAnatomy:birnlex_1097 ! Prepyriform area (also: UBERON:0004725 'piriform cortex') xref: ABA:PIR ! Piriform area xref: BM:Tel-PRP ! prepiriform cortex is_a: UBERON:0000064 ! organ part relationship: spatially_disjoint_from UBERON:0004069 {source="ABA"} ! accessory olfactory bulb relationship: spatially_disjoint_from UBERON:0002266 {source="ABA"} ! anterior olfactory nucleus relationship: spatially_disjoint_from UBERON:0002893 {source="ABA"} ! nucleus of lateral olfactory tract synonym: "gyrus olfactorius lateralis" EXACT LATIN [FMA:TA, FMA:62484] xref: SCTID:369104008 ! Entire lateral olfactory gyrus [Term] id: UBERON:0004725 name: piriform cortex def: "In anatomy of animals, the piriform cortex, or pyriform cortex is a region in the brain. The piriform cortex is part of the rhinencephalon situated in the telencephalon. The function of the piriform cortex relates to olfaction, which is the perception of smells. Sometimes called the olfactory cortex, olfactory lobe or paleopallium, piriform cortical regions are present in the brains of amphibians, reptiles and mammals. The piriform cortex is among three areas that emerge in the telencephalon of amphibians, situated caudally to a dorsal area, which is caudal to a hippocampal area. Farther along the phylogenic timeline, the telencephalic bulb of reptiles as viewed in a cross section of the transverse plane extends with the archipallial hippocampus folding toward the midline and down as the dorsal area begins to form a recognizable cortex. As mammalian cerebrums developed, volume of the dorsal cortex increased in slightly greater proportion, as compared proportionally with increased overall brain volume, until it enveloped the hippocampal regions. Recognized as neopallium or neocortex, enlarged dorsal areas envelop the paleopallial piriform cortex in humans and Old World monkeys. Among taxonomic groupings of mammals, the piriform cortex and the olfactory bulb become proportionally smaller in the brains of phylogenically younger species. The piriform cortex occupies a greater proportion of the overall brain and of the telencephalic brains of insectivores than in primates. The piriform cortex continues to occupy a consistent albeit small and declining proportion of the increasingly large telencephalon in the most recent primate species while the volume of the olfactory bulb becomes less in proportion. It is Brodmann area 27." [Wikipedia:Piriform_cortex] synonym: "primary olfactory cortex" RELATED INCONSISTENT [Wikipedia:Piriform_cortex] synonym: "pyriform cortex" RELATED [Wikipedia:Piriform_cortex] synonym: "pyriform lobe" RELATED [Wikipedia:Piriform_cortex] synonym: "piriform area" RELATED [MA:0000978, BTO:0002651] synonym: "primary olfactory areas" EXACT [NIF_GrossAnatomy:birnlex_2706] synonym: "piriform lobe" RELATED [BTO:0002651] xref: MA:0000978 ! piriform cortex xref: Wikipedia:Piriform_cortex ! piriform cortex xref: NIF_GrossAnatomy:birnlex_1097 ! Piriform cortex (also: UBERON:0002590 'prepyriform area') xref: BTO:0002651 ! piriform area xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Human_brainstem_anterior_view_2_description.JPG/200px-Human_brainstem_anterior_view_2_description.JPG xref: EV:0100178 ! primary olfactory cortex is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002894 ! olfactory cortex relationship: part_of UBERON:0001893 ! telencephalon synonym: "cortex piriformis" RELATED LATIN [Wikipedia:Piriform_cortex] xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Human_brainstem_anterior_view_2_description.JPG xref: SCTID:369098004 ! Entire piriform area [Term] id: UBERON:0004726 name: vasa recta def: "In the blood supply of the kidney, the vasa recta renis (or straight arteries of kidney, or straight arterioles of kidney) form a series of straight capillaries in the medulla. They lie parallel to the loop of Henle. These vessels branch off the efferent arterioles of juxtamedullary nephrons (those nephrons closest to the medulla), enter the medulla, and surround the loop of Henle." [Wikipedia:Vasa_recta] comment: TODO - is this a vein or set of veins? in MA it is a venous blood vessel synonym: "arteria recta" RELATED [Wikipedia:Vasa_recta] synonym: "arteriae rectae" RELATED [Wikipedia:Vasa_recta] synonym: "arteriolae recti" RELATED [Wikipedia:Vasa_recta] synonym: "vasa rectae" RELATED [Wikipedia:Vasa_recta] synonym: "vasa recta of kidney" EXACT [FMA:72006] synonym: "kidney vasa recta" EXACT [MP:0011324] synonym: "renal medullary capillary" EXACT [EMAPA:30043] synonym: "set of straight arterioles of kidney" EXACT [FMA:72006] synonym: "straight arterioles of kidney" EXACT [FMA:72006] xref: FMA:72006 ! set of straight arterioles of kidney xref: MA:0002595 ! vasa recta xref: EMAPA:30043 ! renal medullary capillary xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/21/Kidney_nephron.png/200px-Kidney_nephron.png is_a: UBERON:0001140 ! renal vein synonym: "vasa recta renis" EXACT LATIN [FMA:TA, FMA:72006] synonym: "arteriolae rectae renis" EXACT LATIN [FMA:TA, FMA:72006] xref: galen:ArteriaeRectae synonym: "arteriolae rectae renis" RELATED LATIN [Wikipedia:Vasa_recta] xref: http://upload.wikimedia.org/wikipedia/commons/2/21/Kidney_nephron.png [Term] id: UBERON:0004740 name: basibranchial def: "Median ventral cartilage or bony element at the ventral point of a branchial arch, behind the tongue." [http://www.fishbase.org/Glossary/Glossary.php?q=basibranchial&sc=is, http://www.merriam-webster.com/dictionary/basibranchial] synonym: "basibranchials" EXACT [ZFA:0000170] synonym: "copula I" RELATED [AAO:0000686] xref: AAO:0000686 ! basibranchial xref: ZFA:0000170 ! basibranchial xref: EFO:0003503 ! basibranchial is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0005886 {source="ZFA"} ! pharyngeal arch 3-7 skeleton xref: TAO:0000170 ! basibranchial bone property_value: external_definition "Medial element to which other parts of the hyoid apparatus are attached.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000686", date_retrieved="2012-06-20", source="AAO:Duellman_and_Trueb_1994"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of hyoid apparatus skeleton (AAO:0000682)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000686", date_retrieved="2012-06-20"} property_value: external_definition "Replacement bone that is ventral, median, and associated with a single pharyngeal arch in the pharyngeal arch 3-7 skeleton.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000170", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass basibranchial element (TAO:0001914)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000170", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from copula (TAO:0001220)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000170", date_retrieved="2012-08-14"} synonym: "basibranchial bone" EXACT [TAO:0000170] [Term] id: UBERON:0004651 name: scapula spine def: "a prominent plate of bone, which crosses obliquely the medial four-fifths of the scapula at its upper part, and separates the supra- from the infraspinatous fossa." [Wikipedia:Spine_of_scapula] comment: Taxon notes: the cleithrum, the major shoulder bone of extinct land vertebrate ancestors,.. appears to survive as the scapular spine in living mammals[Matsuoka, PMC1352163] synonym: "scapular spine" RELATED [FMA:13453, MA:0002806] synonym: "spine of scapula" EXACT [FMA:13453] xref: FMA:13453 ! Spine of scapula xref: MA:0002806 ! scapula spine xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a6/Gray205_left_scapula_lateral_view.png/200px-Gray205_left_scapula_lateral_view.png xref: EMAPA:25123 ! spine is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0001124 {source="FMA"} ! pectoral limb scapula relationship: homologous_to UBERON:0004741 ! cleithrum xref: SCTID:181916005 ! Entire spine of scapula synonym: "spina scapulae" RELATED LATIN [Wikipedia:Spine_of_scapula] xref: http://upload.wikimedia.org/wikipedia/commons/a/a6/Gray205_left_scapula_lateral_view.png [Term] id: UBERON:0004741 name: cleithrum def: "Dermal bone on the margin of the scapula. The cleithrum is attached to the skull in fishes, but free from the latter in amphibians and disappears early in the evolution of reptiles." [VSAO:0000187, Wikipedia:Cleithrum] comment: Taxon notes: Found in some early members of Chelonia (e.g. Triassochelys), but missing in all later forms.[VSAO] synonym: "cleithra" EXACT PLURAL [ZFA:0000184] synonym: "cleithrum bone" EXACT PLURAL [] xref: AAO:0000750 ! cleithrum xref: ZFA:0000184 ! cleithrum xref: EFO:0003507 ! cleithrum xref: TAO:0000184 ! cleithrum xref: VSAO:0000187 ! cleithrum is_a: UBERON:0008907 {source="ZFA", source="ZFIN:ZDB-PUB-060210-7"} ! dermal bone relationship: part_of UBERON:0007831 {source="ZFA"} ! pectoral girdle skeleton relationship: never_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: connected_to UBERON:0003113 {gci_relation="part_of", gci_filler="NCBITaxon:32443"} ! dermatocranium property_value: external_definition "Paired bones of intramembranous origin. Each cleithrum extends medially from a point near the suprascapular-scapular articulation to invest the anterior margin of the suprascapula, and occasionoally it may extend to the dorsal (medial) surface. Usually, this bone is bifurcate.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000750", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of scapular area (AAO:0000935)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000750", date_retrieved="2012-06-20"} property_value: external_definition "Dermal bone that articulates dorsally with the supracleithrum and ventro-medially with the scapula and coracoid and mesocoracoid bone when the last bone is present. With the posttemporal and supracleithrum, the cleithrum supports the primary pectoral girdle. The cleithrum is located immediately behind the branchial cavity.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000184", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "cleithrum@fr" RELATED [TAO:0000184] synonym: "clithra@fr" RELATED [TAO:0000184] synonym: "clithrum@fr" RELATED [TAO:0000184] property_value: external_comment "Commonly, the cleithrum is a large, well-ossified bone provided with a dorsal and a ventral arm that form an angle of about 90 or a few more degrees. The dorsal arm may end in a sharp or spine-like process to articulate with the supracleithrum. At the confluence of both arms the bone presents a blade extending postero-ventrally and that may have different development among fishes. The anterior edge of the cleithrum is usually thick and may produce a medial plate of different degrees of development.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000184", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0011246 name: procoracoid bone comment: In primitive synapsis 3 centers develop in the shoulder: the dorsal center gives rise to the scapula and the two ventral centers produce an anterior coracoid (procoracoid) and posterior coracoid (coracoid). The anterior is homologous to the coracoid of fish[Kardong]. Editor notes: VSAO sais that the procoracoid+coracoid are homologous to the teleost coracoid. Consider adding a separate class for posterior coracoid. synonym: "precoracoid" RELATED [] synonym: "precoracoid bone" RELATED [ISBN10:0073040584] synonym: "anterior coracoid bone" RELATED [ISBN10:0073040584] synonym: "anterior coracoid" RELATED [ISBN10:0073040584] synonym: "procoracoid process" NARROW [] synonym: "procoracoid" RELATED [] is_a: UBERON:0011248 ! procoracoid element is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0007831 ! pectoral girdle skeleton relationship: homologous_to UBERON:0004743 {source="Kardong", notes="fish"} ! coracoid bone xref: http://upload.wikimedia.org/wikipedia/commons/7/79/P.gigas_forelimb.jpg relationship: develops_from UBERON:0011247 ! procoracoid bone cartilaginous condensation [Term] id: UBERON:0011247 name: procoracoid cartilage is_a: UBERON:0011248 ! procoracoid element is_a: UBERON:0007844 ! cartilage element relationship: part_of UBERON:0007831 ! pectoral girdle skeleton [Term] id: UBERON:0011248 ! procoracoid element name: procoracoid element synonym: "procoracoid" EXACT [AAO:0000760] synonym: "precoracoid" RELATED [AAO:0000760] synonym: "precoracoid" RELATED [ISBN10:0073040584] synonym: "anterior coracoid" RELATED [ISBN10:0073040584] is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0007831 ! pectoral girdle skeleton xref: AAO:0000760 ! procoracoid property_value: external_definition "Cartilaginous, paired structures located on the anterolateral portions of the zonal area of the pectoral girdle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000760", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of zonal element (AAO:0000936)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000760", date_retrieved="2012-06-20"} [Term] id: UBERON:0004743 ! coracoid bone name: coracoid bone def: "Endochondral bone that is paired and forms part of the socket for the humerus in tetrapods and acts as base of the pectoral fin in fish." [VSAO:curator, Wikipedia:Coracoid] comment: Editor notes: check developmental relationships. Taxon notes: In Theria, coracoid bones non-existent or fused with the shoulder blades to form coracoid processes[WP]. Procoracoid+coracoid are homologuous with coracoid of teleostomi. The coracoid is a triangular shaped-bone that usually has an anteriorly directed long process that may joins its counterpart in some fish groups. It may be perforated by the coracoid foramen or it may be notched dorsally and forms the scapulo-coracoid foramen together with a similar notch of the ventral margin of the scapula[VSAO] Terminology notes: see discussion in Kardong - suggests using procoracoid (anterior coracoid) for the element in birds, reptiles, amphibians and fish, and reserving coracoid for the new synapsid/therian structure. synonym: "coracoids" EXACT [ZFA:0000332] synonym: "clavicula" RELATED [AAO:0000764] synonym: "clavicula posterior" RELATED [AAO:0000764] synonym: "clavicula vera" RELATED [AAO:0000764] synonym: "coracoideum" RELATED [AAO:0000764] synonym: "coracoidien" RELATED [AAO:0000764] synonym: "pars sternalis scapulae" RELATED [AAO:0000764] synonym: "metacoracoid " RELATED [VSAO:0000158] synonym: "coracoid" EXACT [ZFA:0000332] xref: AAO:0000764 ! coracoid xref: ZFA:0000332 ! coracoid xref: VSAO:0000158 ! coracoid is_a: UBERON:0002513 {source="VSAO"} ! endochondral bone relationship: part_of UBERON:0007831 {source="VSAO"} ! pectoral girdle skeleton relationship: develops_from UBERON:0004753 ! scapulocoracoid relationship: never_in_taxon NCBITaxon:32525 {reference="ISBN:0-03-910284-X"} ! Theria xref: TAO:0000332 ! coracoid property_value: external_definition "Paired cartilaginous structures or endochondral bones located on the posterolateral portions of the zonal area of the pectoral girdle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000764", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of zonal element (AAO:0000936)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000764", date_retrieved="2012-06-20"} property_value: external_definition "Endochondral bone that articulates dorsally with the scapula and with the mesocoracoid when the latter is present, posteriorly with the lower two or three proximal radials and antero-ventrally with the cleithrum. The coracoid develops from the scapulo-coracoid cartilage. The coracoid is paired.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000332", date_retrieved="2012-08-14", source="TAO:GA_TG", source="TAO:wd"} synonym: "coracocïde@fr" RELATED [TAO:0000332] synonym: "hypocoracocïde@fr" RELATED [TAO:0000332] property_value: external_comment "The coracoid is a triangular shaped-bone that usually has an anteriorly directed long process that may joins its counterpart in some fish groups. It may be perforated by the coracoid foramen or it may be notched dorsally and forms the scapulo-coracoid foramen together with a similar notch of the ventral margin of the scapula.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000332", date_retrieved="2012-09-06", source="Curator"} [Term] id: UBERON:0006633 ! coracoid process of scapula name: coracoid process of scapula def: "The coracoid process is a small hook-like structure on the lateral edge of the superior anterior portion of the scapula. Pointing laterally forward, it, together with the acromion, serves to stabilize the shoulder joint. It is palpable in the deltopectoral groove between the deltoid and pectoralis major muscles. It is the site of attachment for several structures: * The pectoralis minor muscle - to 3rd to 5th ribs. * The short head of biceps brachii muscle - to Radial tuberosity. * The coracobrachialis muscle - to medial humerus. * The coracoclavicular ligament - to the clavicle. (The ligament is formed by the conoid ligament and trapezoid ligament.) * The coracoacromial ligament - to the acromion[WP]." [Wikipedia:Coracoid_process] synonym: "coracoid process of the scapula" EXACT [Wikipedia:Coracoid_process] synonym: "coracoid process" EXACT [Wikipedia:Coracoid_process] xref: FMA:13455 ! Coracoid process xref: EMAPA:25121 ! coracoid process xref: SCTID:181912007 ! Entire coracoid process of scapula is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0001124 {source="FMA", source="EMAPA"} ! pectoral limb scapula relationship: only_in_taxon NCBITaxon:40674 ! Mammalia disjoint_from: UBERON:0004743 ! coracoid synonym: "processus coracoideus" RELATED LATIN [Wikipedia:Coracoid_process] xref: http://upload.wikimedia.org/wikipedia/commons/a/a6/Gray205_left_scapula_lateral_view.png [Term] id: UBERON:0004745 name: parasphenoid def: "a tooth- or denticle-covered plate which is attached to the sphenoid stem[Palaeos]." [http://palaeos.com/vertebrates/bones/braincase/sphenethmoid.html] synonym: "keilbein" RELATED [AAO:0000385] synonym: "os parasphenoidale" RELATED [AAO:0000385] synonym: "os sphenoideum" RELATED [AAO:0000385] synonym: "parabasale" RELATED [AAO:0000385] xref: AAO:0000385 ! parasphenoid xref: ZFA:0000561 ! parasphenoid is_a: UBERON:0002514 ! intramembranous bone relationship: part_of UBERON:0003111 {source="ZFA"} ! sphenoid region relationship: part_of UBERON:0003112 {source="ZFA"} ! olfactory region relationship: part_of UBERON:0012072 {source="Kardong", notes="palatal series"} ! palatal part of dermatocranium relationship: overlaps UBERON:0001697 {source="ZFA-modified"} ! orbit relationship: part_of UBERON:0001703 {source="ZFA"} ! neurocranium xref: TAO:0000561 ! parasphenoid property_value: external_definition "Azygous, dermal bone of intramembranous origin that underlies the ventral surface of the braincase in anurans and salamanders. In caecilians, the parasphenoid and other bones are fused to form the Os basale.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000385", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000385", date_retrieved="2012-06-20"} property_value: external_definition "Dermal bone that forms part of the base of the skull and the lateral walls of the braincase through its ascending processes. It may articulate with the vomer anteriorly, the prootics and exoccipitals laterally, and the basioccipital posteriorly. The parasphenoid is an elongate median bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000561", date_retrieved="2012-08-14", source="TAO:GA_TG"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps parasphenoid-basioccipital joint (TAO:0001832)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000561", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps parasphenoid-pterosphenoid joint (TAO:0002217)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000561", date_retrieved="2012-08-14"} [Term] id: UBERON:0004748 name: obsolete autopalatine is_obsolete: true consider: AAO:0000372 ! palatine consider: ZFA:0000620 ! autopalatine !consider: TAO:0000620 ! autopalatine property_value: external_definition "Sliver of bone that invest part of or all the posterior aspect of each antorbital plane.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000372", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: external_definition "The cartilaginous autopalatine forms from the anterior palatoquadrate arch. The first sign of ossification is visible at the anterior tip where it articulates with the maxilla (7.6 mm). In adults there are three processes at the anterior portion of the palatine: a ventromedial process, which forms the socket of the small ball- and- socket joint with the preethmoid; a dorsomedial process, which is connected by a short ligament to the ethmoid; and a lateral process, which extends toward the first infraorbital. Possession of a dorsomedial process, which abuts the ethmoid, is a unique feature shared by Cypriniformes (Fink and Fink, 1981). The palatine has two components, the autopalatine (derived from pars autopalatine) and the dermal component having teeth, the dermopalatine Arratia & Schultze 1990. The element in cypriniforms is only the cartilage part, so that it is more correct to name it autopalatine and not as palatine in general that it implies a fusion of elements (as in perciforms).[ZFA]" xsd:string {ontology="ZFA", external_class="ZFA:0000620", date_retrieved="2012-08-08", source="ZFIN:curator"} [Term] id: UBERON:0004807 name: respiratory system epithelium def: "An epithelium that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius epithelial tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "epithelial tissue of respiratory system" EXACT [OBOL:automatic] synonym: "epithelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "epithelium of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001823 ! respiratory system epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001004 ! part_of respiratory system xref: VHOG:0000981 ! respiratory epithelium (also: UBERON:0004802 'respiratory tract epithelium') [Term] id: UBERON:0004802 name: respiratory tract epithelium def: "An epithelium that is part of a respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "respiratory epithelium" RELATED [BTO:0000419] synonym: "epithelial tissue of respiratory tract" EXACT [OBOL:automatic] synonym: "epithelium of respiratory tract" EXACT [OBOL:automatic] synonym: "respiratory tract epithelial tissue" EXACT [OBOL:automatic] synonym: "airway epithelium" RELATED [BTO:0000419] xref: MA:0001480 ! respiratory tract epithelium xref: BTO:0000419 ! respiratory epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000065 ! part_of respiratory tract relationship: part_of UBERON:0000072 ! segment of respiratory tract xref: SCTID:321764001 ! Entire respiratory epithelium xref: VHOG:0000981 ! respiratory epithelium (also: UBERON:0004807 'respiratory system epithelium') [Term] id: UBERON:0004785 name: respiratory system mucosa def: "A mucosa that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] comment: TODO - split respiratory tract mucosa from respiratory system mucosa synonym: "respiratory mucosa" RELATED [BTO:0000973] synonym: "apparatus respiratorius mucosa" EXACT [OBOL:automatic] synonym: "apparatus respiratorius mucosa of organ" EXACT [OBOL:automatic] synonym: "apparatus respiratorius mucous membrane" EXACT [OBOL:automatic] synonym: "mucosa of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "mucosa of organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "mucosa of organ of respiratory system" EXACT [OBOL:automatic] synonym: "mucosa of respiratory system" EXACT [OBOL:automatic] synonym: "mucous membrane of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "mucous membrane of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system mucosa of organ" EXACT [OBOL:automatic] synonym: "respiratory system mucous membrane" EXACT [OBOL:automatic] xref: MA:0001827 ! respiratory system mucosa xref: BTO:0000973 ! respiratory mucosa xref: GAID:304 ! respiratory mucosa xref: EMAPA:18334 ! mucous membranes (also: UBERON:0001824 'mucosa of larynx') xref: MESH:A04.760 ! respiratory mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001004 ! part_of respiratory system [Term] id: UBERON:0004775 name: outer renal medulla vasa recta def: "A vasa recta that is part of a outer medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "outer medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "outer zone of medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "outer zone of renal medulla vasa recta" EXACT [OBOL:automatic] synonym: "vasa recta of outer medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of outer renal medulla" EXACT [OBOL:automatic] synonym: "vasa recta of outer zone of medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of outer zone of renal medulla" EXACT [OBOL:automatic] synonym: "kidney outer renal medulla vasa recta" EXACT [MP:0011330] synonym: "kidney outer medulla vasa recta" EXACT [MP:0011330] xref: MA:0002597 ! outer renal medulla vasa recta intersection_of: UBERON:0004726 ! vasa recta intersection_of: part_of UBERON:0001293 ! part_of outer medulla of kidney [Term] id: UBERON:0004776 name: inner renal medulla vasa recta def: "A vasa recta that is part of a inner medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "inner medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "inner zone of medulla of kidney vasa recta" EXACT [OBOL:automatic] synonym: "inner zone of renal medulla vasa recta" EXACT [OBOL:automatic] synonym: "set of inner region of renal pyramids vasa recta" EXACT [OBOL:automatic] synonym: "vasa recta of inner medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of inner renal medulla" EXACT [OBOL:automatic] synonym: "vasa recta of inner zone of medulla of kidney" EXACT [OBOL:automatic] synonym: "vasa recta of inner zone of renal medulla" EXACT [OBOL:automatic] synonym: "vasa recta of set of inner region of renal pyramids" EXACT [OBOL:automatic] xref: MA:0002596 ! inner renal medulla vasa recta intersection_of: UBERON:0004726 ! vasa recta intersection_of: part_of UBERON:0001294 ! part_of inner medulla of kidney [Term] id: UBERON:0004777 name: respiratory system submucosa def: "A submucosa that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius submucosa" EXACT [OBOL:automatic] synonym: "submucosa of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "submucosa of respiratory system" EXACT [OBOL:automatic] xref: MA:0001822 ! respiratory system submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001004 ! part_of respiratory system relationship: part_of UBERON:0003570 ! respiratory system connective tissue [Term] id: UBERON:0004778 name: larynx submucosa def: "A submucosa that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "submucosa of larynx" EXACT [OBOL:automatic] xref: MA:0002728 ! larynx submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001737 ! part_of larynx xref: SCTID:361941005 ! Entire submucosa of larynx [Term] id: UBERON:0004779 name: respiratory system lamina propria def: "A lamina propria that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius lamina propria" EXACT [OBOL:automatic] synonym: "apparatus respiratorius lamina propria mucosa" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of respiratory system" EXACT [OBOL:automatic] synonym: "lamina propria of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lamina propria of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system lamina propria mucosa" EXACT [OBOL:automatic] xref: MA:0001821 ! respiratory system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001004 ! part_of respiratory system relationship: part_of UBERON:0003570 ! respiratory system connective tissue relationship: part_of UBERON:0004785 {is_inferred="true", source="reference_0000032"} ! respiratory system mucosa [Term] id: UBERON:0004780 name: gastrointestinal system lamina propria xref: MA:0001899 ! gastrointestinal system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0005409 ! gastrointestinal system xref: ncithesaurus:Gastrointestinal_Tract_Lamina_Propria ! Gastrointestinal System Lamina Propria def: "A lamina propria that is part of a gastrointestinal system." [OBOL:automatic] relationship: part_of UBERON:0004786 {is_inferred="true", source="reference_0000032"} ! gastrointestinal system mucosa xref: UMLS:C1708197 [Term] id: UBERON:0004781 name: gall bladder lamina propria def: "A lamina propria that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "gall bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "gallbladder lamina propria" EXACT [OBOL:automatic] synonym: "gallbladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of gall bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of gallbladder" EXACT [OBOL:automatic] synonym: "lamina propria of gall bladder" EXACT [OBOL:automatic] synonym: "lamina propria of gallbladder" EXACT [OBOL:automatic] synonym: "biliary lamina propria" RELATED [MA:0001633] xref: MA:0001633 ! gall bladder lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0002110 ! part_of gallbladder xref: ncithesaurus:Gallbladder_Lamina_Propria ! Gallbladder Lamina Propria relationship: part_of UBERON:0005033 {is_inferred="true", source="reference_0000032"} ! mucosa of gallbladder xref: UMLS:C1708175 [Term] id: UBERON:0004782 name: gastrointestinal system serosa def: "A serous membrane that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "digestive system serosa" EXACT [OBOL:automatic] synonym: "digestive system serous membrane" EXACT [OBOL:automatic] synonym: "gastrointestinal system serous membrane" EXACT [OBOL:automatic] synonym: "serosa of digestive system" EXACT [OBOL:automatic] synonym: "serosa of gastrointestinal system" EXACT [OBOL:automatic] synonym: "serous membrane of digestive system" EXACT [OBOL:automatic] synonym: "serous membrane of gastrointestinal system" EXACT [OBOL:automatic] xref: MA:0001522 ! gastrointestinal system serosa intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0005409 ! gastrointestinal system relationship: part_of UBERON:0005409 ! gastrointestinal system [Term] id: UBERON:0004783 name: gall bladder serosa def: "A serous membrane that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "gall bladder serous membrane" EXACT [OBOL:automatic] synonym: "gallbladder serosa" EXACT [OBOL:automatic] synonym: "gallbladder serous membrane" EXACT [OBOL:automatic] synonym: "serosa of gall bladder" EXACT [OBOL:automatic] synonym: "serosa of gallbladder" EXACT [OBOL:automatic] synonym: "serous membrane of gall bladder" EXACT [OBOL:automatic] synonym: "serous membrane of gallbladder" EXACT [OBOL:automatic] synonym: "biliary serosa" RELATED [MA:0001634] synonym: "serous coat of gallbladder" EXACT [FMA:14659] synonym: "tunica serosa (vesica biliaris)" EXACT [FMA:14659] xref: MA:0001634 ! gall bladder serosa xref: FMA:14659 ! Serosa of gallbladder intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002110 ! part_of gallbladder synonym: "tunica serosa vesicae biliaris" EXACT LATIN [FMA:TA, FMA:14659] xref: SCTID:362197006 ! Entire serosa of gallbladder [Term] id: UBERON:0004784 name: heart ventricle wall def: "An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of cardiac ventricle" EXACT [OBOL:automatic] synonym: "anatomical wall of heart ventricle" EXACT [OBOL:automatic] synonym: "anatomical wall of lower chamber of heart" EXACT [OBOL:automatic] synonym: "anatomical wall of ventricle of heart" EXACT [OBOL:automatic] synonym: "cardiac ventricle anatomical wall" EXACT [OBOL:automatic] synonym: "cardiac ventricle wall" EXACT [OBOL:automatic] synonym: "heart ventricle anatomical wall" EXACT [OBOL:automatic] synonym: "lower chamber of heart anatomical wall" EXACT [OBOL:automatic] synonym: "lower chamber of heart wall" EXACT [OBOL:automatic] synonym: "ventricle of heart anatomical wall" EXACT [OBOL:automatic] synonym: "ventricle of heart wall" EXACT [OBOL:automatic] synonym: "wall of cardiac ventricle" EXACT [OBOL:automatic] synonym: "wall of heart ventricle" EXACT [OBOL:automatic] synonym: "wall of lower chamber of heart" EXACT [OBOL:automatic] synonym: "wall of ventricle of heart" EXACT [OBOL:automatic] synonym: "wall of ventricle" RELATED [MA:0002791] synonym: "ventricular wall" EXACT [FMA:13884] xref: MA:0002791 ! heart ventricle wall xref: FMA:13884 ! Wall of ventricle intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0002082 ! part_of cardiac ventricle [Term] id: UBERON:0004786 ! gastrointestinal system mucosa name: gastrointestinal system mucosa comment: The gut mucosa of amphioxus has insulin-secreting cells. PMID:16417468 synonym: "gut mucosa" EXACT [BTO:0000546] synonym: "mucosa of gut" EXACT [UBERON:cjm] synonym: "gut mucuous membrane" EXACT [UBERON:cjm] synonym: "digestive tract mucosa" EXACT [UBERON:cjm] intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0005409 ! gastrointestinal system relationship: part_of UBERON:0001555 ! digestive tract relationship: adjacent_to UBERON:0006909 {source="BTO-modified"} ! lumen of gut relationship: has_part CL:0002067 {source="PMID:16417468"} ! type A enterocrine cell relationship: has_part CL:0000168 {gci_relation="part_of", gci_filler="NCBITaxon:7737", source="PMID:16417468"} ! insulin secreting cell relationship: has_part CL:0000172 {source="PMID:16417468"} ! somatostatin secreting cell relationship: has_part CL:0000696 {source="PMID:16417468"} ! PP cell xref: SCTID:410433007 ! Structure of digestive system mucous membrane xref: BTO:0000546 ! gut mucosa xref: MA:0001521 ! gastrointestinal system mucosa def: "A mucosa that is part of a gastrointestinal system." [OBOL:automatic] [Term] id: UBERON:0004789 name: larynx mucous gland def: "A mucous gland that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucous gland of larynx" EXACT [OBOL:automatic] xref: MA:0001767 ! larynx mucous gland intersection_of: UBERON:0000414 ! mucous gland intersection_of: part_of UBERON:0001737 ! part_of larynx relationship: part_of UBERON:0001824 ! mucosa of larynx [Term] id: UBERON:0004790 name: skin mucous gland comment: Editor notes; See comments for 'skin mucus' synonym: "skin mucus gland" EXACT [OBOL:automatic] synonym: "mucous gland of entire skin" EXACT [OBOL:automatic] synonym: "mucous gland of skin of body" EXACT [OBOL:automatic] synonym: "skin of body mucous gland" EXACT [OBOL:automatic] xref: MA:0000148 ! skin mucous gland intersection_of: UBERON:0000414 ! mucous gland intersection_of: part_of UBERON:0002097 ! part_of skin of body subset: organ_slim def: "A mucous gland that is part of a skin of body." [OBOL:automatic] [Term] id: UBERON:0010152 name: skin mucus comment: Editor notes: Consider making a specific class e.g. mucus coating to represent the entire coating rather than an portion of secretion of a mucus gland in the skin. Candidate definition - "The epidermal mucus of fish regulates swimming speed by controlling the hydrodynamic resistance of the skin surface. The mucus is also presumed to serve as a defence against pathogenic organisms and is intimately associated with osmoregulation." [BTO:0005082] synonym: "epidermal mucus" RELATED [BTO:0005082] is_a: UBERON:0000456 {source="BTO"} ! bodily secretion relationship: develops_from UBERON:0000414 {source="BTO"} ! mucous gland xref: BTO:0005082 ! skin mucus [Term] id: UBERON:0004791 name: thymus trabecula def: "A trabecula that is part of a thymus [Automatically generated definition]." [OBOL:automatic] synonym: "thymus gland trabecula" EXACT [OBOL:automatic] synonym: "trabecula of thymus" EXACT [OBOL:automatic] synonym: "thymic trabecula" EXACT [OBOL:automatic] synonym: "trabecula of thymus gland" EXACT [OBOL:automatic] xref: MA:0002674 ! thymus trabecula xref: ncithesaurus:Thymic_Trabecula ! Thymic Trabecula intersection_of: UBERON:0000440 ! trabecula intersection_of: part_of UBERON:0002370 ! part_of thymus relationship: part_of UBERON:0002370 {source="MA"} ! thymus xref: UMLS:C1515431 [Term] id: UBERON:0004792 name: secretion of endocrine pancreas def: "A secretion that is part of a endocrine pancreas [Automatically generated definition]." [OBOL:automatic] synonym: "pars endocrina pancreatis secretion" EXACT [OBOL:automatic] synonym: "endocrine pancreas secretion" EXACT [OBOL:automatic] synonym: "secretion of pars endocrina pancreatis" EXACT [OBOL:automatic] synonym: "pancreatic endocrine secretion" EXACT [ncithesaurus:Pancreatic_Endocrine_Secretion] xref: MA:0002517 ! endocrine pancreas secretion xref: ncithesaurus:Pancreatic_Endocrine_Secretion ! Pancreatic Endocrine Secretion intersection_of: UBERON:0000456 ! bodily secretion intersection_of: part_of UBERON:0000016 ! part_of endocrine pancreas xref: UMLS:C1518866 [Term] id: UBERON:0004793 name: secretion of exocrine pancreas def: "A secretion that is part of a exocrine pancreas [Automatically generated definition]." [OBOL:automatic] synonym: "pars exocrina pancreatis secretion" EXACT [OBOL:automatic] synonym: "exocrine pancreas secretion" EXACT [OBOL:automatic] synonym: "secretion of pars exocrina pancreatis" EXACT [OBOL:automatic] synonym: "pancreatic exocrine secretion" EXACT [ncithesaurus:Pancreatic_Exocrine_Secretion] xref: MA:0002518 ! exocrine pancreas secretion xref: ncithesaurus:Pancreatic_Exocrine_Secretion ! Pancreatic Exocrine Secretion intersection_of: UBERON:0000456 ! bodily secretion intersection_of: part_of UBERON:0000017 ! part_of exocrine pancreas xref: UMLS:C1518867 [Term] id: UBERON:0004794 name: esophagus secretion def: "A secretion that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "gullet secretion" EXACT [OBOL:automatic] synonym: "oesophagus secretion" EXACT [OBOL:automatic] synonym: "secretion of esophagus" EXACT [OBOL:automatic] synonym: "secretion of gullet" EXACT [OBOL:automatic] synonym: "secretion of oesophagus" EXACT [OBOL:automatic] synonym: "esophageal secretion" EXACT [FMA:79662] xref: MA:0002514 ! esophagus secretion xref: FMA:79662 ! esophageal secretion intersection_of: UBERON:0000456 ! bodily secretion intersection_of: part_of UBERON:0001043 ! part_of esophagus xref: ncithesaurus:Esophagus_Secretion ! Esophagus Secretion xref: UMLS:C0227179 [Term] id: UBERON:0004795 name: pancreas secretion def: "A secretion that is part of a pancreas [Automatically generated definition]." [OBOL:automatic] synonym: "secretion of pancreas" EXACT [OBOL:automatic] synonym: "pancreatic secretion" EXACT [OBOL:automatic] xref: MA:0002516 ! pancreas secretion xref: ncithesaurus:Pancreatic_Secretion ! Pancreatic Secretion intersection_of: UBERON:0000456 ! bodily secretion intersection_of: part_of UBERON:0001264 ! part_of pancreas xref: UMLS:C0030296 [Term] id: UBERON:0004798 name: respiratory system basal lamina def: "A basal lamina that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius basal lamina" EXACT [OBOL:automatic] synonym: "apparatus respiratorius basal lamina of connective tissue" EXACT [OBOL:automatic] synonym: "basal lamina of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "basal lamina of connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "basal lamina of connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "basal lamina of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system basal lamina of connective tissue" EXACT [OBOL:automatic] xref: MA:0001816 ! respiratory system basal lamina intersection_of: UBERON:0000482 ! basal lamina intersection_of: part_of UBERON:0001004 ! part_of respiratory system [Term] id: UBERON:0004799 name: trachea basal lamina def: "A basal lamina that is part of a respiratory airway [Automatically generated definition]." [OBOL:automatic] synonym: "basal lamina of connective tissue of respiratory airway" EXACT [OBOL:automatic] xref: MA:0001855 ! trachea basal lamina intersection_of: UBERON:0000482 ! basal lamina intersection_of: part_of UBERON:0001005 ! part_of respiratory airway xref: ncithesaurus:Trachea_Basal_Lamina ! Trachea Basal Lamina xref: UMLS:C1710454 [Term] id: UBERON:0004800 name: bronchus basal lamina def: "A basal lamina that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "basal lamina of bronchi" EXACT [OBOL:automatic] synonym: "basal lamina of bronchial trunk" EXACT [OBOL:automatic] synonym: "basal lamina of bronchus" EXACT [OBOL:automatic] synonym: "basal lamina of connective tissue of bronchi" EXACT [OBOL:automatic] synonym: "basal lamina of connective tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "basal lamina of connective tissue of bronchus" EXACT [OBOL:automatic] synonym: "bronchi basal lamina" EXACT [OBOL:automatic] synonym: "bronchi basal lamina of connective tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk basal lamina" EXACT [OBOL:automatic] synonym: "bronchial trunk basal lamina of connective tissue" EXACT [OBOL:automatic] synonym: "bronchus basal lamina of connective tissue" EXACT [OBOL:automatic] xref: MA:0001833 ! bronchus basal lamina intersection_of: UBERON:0000482 ! basal lamina intersection_of: part_of UBERON:0002185 ! part_of bronchus xref: ncithesaurus:Bronchus_Basal_Lamina ! Bronchus Basal Lamina xref: UMLS:C1707050 [Term] id: UBERON:0004803 name: penis epithelium def: "An epithelium that is part of a penis [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of penis" EXACT [OBOL:automatic] synonym: "epithelium of penis" EXACT [OBOL:automatic] synonym: "penis epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001742 ! penis epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000989 ! part_of penis xref: EHDAA2:0004039 ! penis epithelium [Term] id: UBERON:0004804 name: oviduct epithelium def: "An epithelium that is part of a oviduct [Automatically generated definition]." [OBOL:automatic] comment: in FMA, epithelium of uterine tube is a subclass of ciliated columnar epithelium. MA introduces subtypes: ciliated columnar and cuboidal. We map the FMA type according to its relationships, not its label synonym: "epithelial tissue of oviduct" EXACT [OBOL:automatic] synonym: "epithelium of oviduct" EXACT [OBOL:automatic] synonym: "oviduct epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelium of uterine tube" EXACT [FMA:62016] synonym: "epithelium of fallopian tube" EXACT [OBOL:automatic] xref: MA:0001718 ! oviduct epithelium xref: BTO:0002402 ! oviduct epithelium xref: EMAPA:29043 ! epithelial layer of oviduct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000993 ! part_of oviduct relationship: part_of UBERON:0003889 ! fallopian tube [Term] id: UBERON:0007589 name: ciliated columnar oviduct epithelium comment: in FMA, epithelium of uterine tube is a subclass of ciliated columnar epithelium. MA introduces subtypes: ciliated columnar and cuboidal. We map the FMA type according to its relationships, not its label xref: MA:0001719 ! ciliated columnar oviduct epithelium xref: FMA:62016 ! epithelium of uterine tube is_a: UBERON:0004804 {source="MA"} ! oviduct epithelium is_a: UBERON:0007592 {source="FMA"} ! ciliated columnar epithelium intersection_of: UBERON:0007592 ! ciliated columnar epithelium intersection_of: part_of UBERON:0000993 ! part_of oviduct synonym: "uterine tube epithelium" EXACT [FMA:62016] def: "A ciliated columnar epithelium that is part of a oviduct." [OBOL:automatic] [Term] id: UBERON:0007590 name: cuboidal oviduct epithelium xref: MA:0001720 ! cuboidal oviduct epithelium is_a: UBERON:0004804 {source="MA"} ! oviduct epithelium [Term] id: UBERON:0004805 name: seminal vesicle epithelium def: "An epithelium that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of seminal gland" EXACT [OBOL:automatic] synonym: "epithelial tissue of seminal vesicle" EXACT [OBOL:automatic] synonym: "epithelium of seminal gland" EXACT [OBOL:automatic] synonym: "epithelium of seminal vesicle" EXACT [OBOL:automatic] synonym: "seminal gland epithelial tissue" EXACT [OBOL:automatic] synonym: "seminal gland epithelium" EXACT [OBOL:automatic] synonym: "seminal vesicle epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001745 ! seminal vesicle epithelium xref: EMAPA:29771 ! epithelium of seminal vesicle intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000998 ! part_of seminal vesicle xref: ncithesaurus:Seminal_Vesicle_Epithelium ! Seminal Vesicle Epithelium xref: UMLS:C1710049 [Term] id: UBERON:0004806 name: vas deferens epithelium def: "An epithelium that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] synonym: "deferent duct epithelial tissue" EXACT [OBOL:automatic] synonym: "deferent duct epithelium" EXACT [OBOL:automatic] synonym: "ductus deferens epithelial tissue" EXACT [OBOL:automatic] synonym: "ductus deferens epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of deferent duct" EXACT [OBOL:automatic] synonym: "epithelial tissue of ductus deferens" EXACT [OBOL:automatic] synonym: "epithelial tissue of sperm duct" EXACT [OBOL:automatic] synonym: "epithelial tissue of vas deferen" EXACT [OBOL:automatic] synonym: "epithelial tissue of vas deferens" EXACT [OBOL:automatic] synonym: "epithelium of deferent duct" EXACT [OBOL:automatic] synonym: "epithelium of ductus deferens" EXACT [OBOL:automatic] synonym: "epithelium of sperm duct" EXACT [OBOL:automatic] synonym: "epithelium of vas deferen" EXACT [OBOL:automatic] synonym: "epithelium of vas deferens" EXACT [OBOL:automatic] synonym: "sperm duct epithelial tissue" EXACT [OBOL:automatic] synonym: "sperm duct epithelium" EXACT [OBOL:automatic] synonym: "vas deferen epithelial tissue" EXACT [OBOL:automatic] synonym: "vas deferen epithelium" EXACT [OBOL:automatic] synonym: "vas deferens epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001749 ! vas deferens epithelium xref: FMA:225317 ! Epithelium of deferent duct xref: EMAPA:29274 ! epithelium of ductus deferens intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001000 ! part_of vas deferens xref: ncithesaurus:Vas_Deferens_Epithelium ! Vas Deferens Epithelium xref: UMLS:C1710617 [Term] id: UBERON:0004808 name: gastrointestinal system epithelium def: "An epithelium that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "digestive system epithelial tissue" EXACT [OBOL:automatic] synonym: "digestive system epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of digestive system" EXACT [OBOL:automatic] synonym: "epithelial tissue of gastrointestinal system" EXACT [OBOL:automatic] synonym: "epithelium of digestive system" EXACT [OBOL:automatic] synonym: "epithelium of gastrointestinal system" EXACT [OBOL:automatic] synonym: "gastrointestinal system epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001520 ! gastrointestinal system epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005409 ! gastrointestinal system [Term] id: UBERON:0004809 name: salivary gland epithelium def: "An epithelium that is part of a salivary gland [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of salivary gland" EXACT [OBOL:automatic] synonym: "epithelium of salivary gland" EXACT [OBOL:automatic] synonym: "salivary gland epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001587 ! salivary gland epithelium xref: BTO:0004421 ! salivary gland epithelium xref: EMAPA:17753 ! epithelium of sublingual gland primordium xref: EMAPA:17756 ! epithelium of submandibular gland primordium (also: UBERON:0006957 'submandibular gland primordium epithelium') intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001044 ! part_of salivary gland relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer [Term] id: UBERON:0004810 name: nephron tubule epithelium def: "An epithelium that is part of a nephron tubule [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of nephron tubule" EXACT [OBOL:automatic] synonym: "epithelial tissue of renal tubule" EXACT [OBOL:automatic] synonym: "epithelial tissue of tubulus renalis" EXACT [OBOL:automatic] synonym: "epithelium of nephron tubule" EXACT [OBOL:automatic] synonym: "epithelium of renal tubule" EXACT [OBOL:automatic] synonym: "epithelium of tubulus renalis" EXACT [OBOL:automatic] synonym: "nephron tubule epithelial tissue" EXACT [OBOL:automatic] synonym: "nephron tubule epithelium" EXACT [OBOL:automatic] synonym: "renal tubule epithelial tissue" EXACT [OBOL:automatic] synonym: "tubulus renalis epithelial tissue" EXACT [OBOL:automatic] synonym: "tubulus renalis epithelium" EXACT [OBOL:automatic] xref: MA:0001681 ! renal tubule epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001231 ! part_of nephron tubule xref: ncithesaurus:Renal_Tubule_Epithelium ! Renal Tubule Epithelium synonym: "kidney tubule epithelium" EXACT [MA:0001681] xref: UMLS:C1709902 [Term] id: UBERON:0004814 name: upper respiratory tract epithelium def: "An epithelium that is part of a upper respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of upper respiratory tract" EXACT [OBOL:automatic] synonym: "epithelium of upper respiratory tract" EXACT [OBOL:automatic] synonym: "upper respiratory tract epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001912 ! upper respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001557 ! part_of upper respiratory tract [Term] id: UBERON:0004815 name: lower respiratory tract epithelium def: "An epithelium that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "epithelium of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001481 ! lower respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001558 ! part_of lower respiratory tract [Term] id: UBERON:0004816 name: larynx epithelium def: "An epithelium that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of larynx" EXACT [OBOL:automatic] synonym: "epithelium of larynx" EXACT [OBOL:automatic] synonym: "laryngeal epithelium" EXACT [OBOL:automatic] synonym: "larynx epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001765 ! larynx epithelium xref: ncithesaurus:Laryngeal_Epithelium ! Laryngeal Epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001737 ! part_of larynx xref: EHDAA2:0004065 ! laryngeal epithelium xref: UMLS:C0751258 [Term] id: UBERON:0004817 name: lacrimal gland epithelium def: "An epithelium that is part of a lacrimal gland [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lacrimal gland" EXACT [OBOL:automatic] synonym: "epithelium of lacrimal gland" EXACT [OBOL:automatic] synonym: "lacrimal gland epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001297 ! lacrimal gland epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001817 ! lacrimal gland [Term] id: UBERON:0004818 name: terminal bronchus epithelium def: "An epithelium that is part of a terminal bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of terminal bronchus" EXACT [OBOL:automatic] synonym: "epithelium of terminal bronchus" EXACT [OBOL:automatic] synonym: "terminal bronchus epithelial tissue" EXACT [OBOL:automatic] xref: MA:0001851 ! terminal bronchus epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002041 ! part_of terminal bronchus [Term] id: UBERON:0004819 name: kidney epithelium def: "An epithelium that is part of a kidney [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of kidney" EXACT [OBOL:automatic] synonym: "epithelium of kidney" EXACT [OBOL:automatic] synonym: "kidney epithelial tissue" EXACT [OBOL:automatic] xref: MA:0002846 ! kidney epithelium xref: BTO:0000059 ! renal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002113 ! part_of kidney [Term] id: UBERON:0004820 name: bile duct epithelium def: "Epithelium of the gallbladder and the intrahepatic and extrahepatic bile ducts." [BTO:0001513] comment: todo - check if BTO terms need merged synonym: "bile duct epithelial tissue" EXACT [OBOL:automatic] synonym: "biliary duct epithelial tissue" EXACT [OBOL:automatic] synonym: "biliary duct epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of bile duct" EXACT [OBOL:automatic] synonym: "epithelial tissue of biliary duct" EXACT [OBOL:automatic] synonym: "epithelium of bile duct" EXACT [OBOL:automatic] synonym: "epithelium of biliary duct" EXACT [OBOL:automatic] synonym: "biliary epithelium" EXACT [BTO:0001513] xref: MA:0001629 ! bile duct epithelium xref: BTO:0000417 ! bile duct epithelium xref: BTO:0001513 ! biliary epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002394 ! part_of bile duct xref: ncithesaurus:Bile_Duct_Epithelium ! Bile Duct Epithelium xref: UMLS:C1711208 [Term] id: UBERON:0004822 name: extrahepatic bile duct epithelium def: "An epithelium that is part of a extrahepatic bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of extrahepatic bile duct" EXACT [OBOL:automatic] synonym: "epithelium of extrahepatic bile duct" EXACT [OBOL:automatic] synonym: "extrahepatic bile duct epithelial tissue" EXACT [OBOL:automatic] xref: MA:0002661 ! extrahepatic bile duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003703 ! part_of extrahepatic bile duct xref: ncithesaurus:Extrahepatic_Bile_Duct_Epithelium ! Extrahepatic Bile Duct Epithelium xref: UMLS:C1711347 [Term] id: UBERON:0004823 name: intrahepatic bile duct epithelium def: "An epithelium that is part of a intrahepatic bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of intrahepatic bile duct" EXACT [OBOL:automatic] synonym: "epithelium of intrahepatic bile duct" EXACT [OBOL:automatic] synonym: "intrahepatic bile duct epithelial tissue" EXACT [OBOL:automatic] xref: MA:0002662 ! intrahepatic bile duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003704 ! part_of intrahepatic bile duct xref: ncithesaurus:Intrahepatic_Bile_Duct_Epithelium ! Intrahepatic Bile Duct Epithelium xref: UMLS:C1708552 [Term] id: UBERON:0004827 name: thyroid gland medulla def: "A medulla that is part of a thyroid [Automatically generated definition]." [OBOL:automatic] synonym: "medulla of thyroid" EXACT [OBOL:automatic] synonym: "medulla of thyroid follicle" EXACT [OBOL:automatic] synonym: "medulla of thyroid gland" EXACT [OBOL:automatic] synonym: "medulla of thyroid gland follicle" EXACT [OBOL:automatic] synonym: "thyroid follicle medulla" EXACT [OBOL:automatic] synonym: "thyroid gland follicle medulla" EXACT [OBOL:automatic] synonym: "thyroid medulla" EXACT [OBOL:automatic] xref: MA:0000132 ! thyroid gland medulla intersection_of: UBERON:0000958 ! medulla intersection_of: part_of UBERON:0002046 ! part_of thyroid follicle [Term] id: UBERON:0004829 name: urethra skeletal muscle def: "A portion of skeletal muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "skeletal muscle of urethra" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "urethral skeletal muscle" RELATED [MA:0001690] xref: MA:0001690 ! urethra skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0000057 ! part_of urethra relationship: part_of UBERON:0003829 ! urethra muscle [Term] id: UBERON:0004830 name: respiratory system skeletal muscle def: "A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "respiratory system skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "skeletal muscle of respiratory system" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of respiratory system" EXACT [OBOL:automatic] xref: MA:0001829 ! respiratory system skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001004 ! part_of respiratory system [Term] id: UBERON:0004831 name: esophagus skeletal muscle def: "A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophagus skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "gullet skeletal muscle" EXACT [OBOL:automatic] synonym: "gullet skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "oesophagus skeletal muscle" EXACT [OBOL:automatic] synonym: "oesophagus skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of esophagus" EXACT [OBOL:automatic] synonym: "skeletal muscle of gullet" EXACT [OBOL:automatic] synonym: "skeletal muscle of oesophagus" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of esophagus" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of gullet" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of oesophagus" EXACT [OBOL:automatic] xref: MA:0001572 ! esophagus skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001043 ! part_of esophagus relationship: part_of UBERON:0003832 ! esophagus muscle [Term] id: UBERON:0004832 name: anal region skeletal muscle def: "A portion of skeletal muscle tissue that is part of an anal region [Automatically generated definition]." [OBOL:automatic] synonym: "anal part of perineum skeletal muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "anal region skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "anal triangle skeletal muscle" EXACT [OBOL:automatic] synonym: "anal triangle skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "skeletal muscle of anal region" EXACT [OBOL:automatic] synonym: "skeletal muscle of anal triangle" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of anal part of perineum" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of anal region" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of anal triangle" EXACT [OBOL:automatic] xref: MA:0001530 ! anal region skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0004833 name: lip skeletal muscle def: "A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]." [OBOL:automatic] synonym: "lip skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of lip" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of lip" EXACT [OBOL:automatic] xref: MA:0001578 ! lip skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001833 ! part_of lip [Term] id: UBERON:0004834 name: hepatic duct smooth muscle xref: MA:0001640 ! hepatic duct smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005171 ! hepatic duct def: "A smooth muscle tissue that is part of a hepatic duct." [OBOL:automatic] [Term] id: UBERON:0004835 name: epididymis smooth muscle def: "A portion of smooth muscle tissue that is part of a epididymis [Automatically generated definition]." [OBOL:automatic] synonym: "epididymis involuntary muscle" EXACT [OBOL:automatic] synonym: "epididymis non-striated muscle" EXACT [OBOL:automatic] synonym: "epididymis smooth muscle tissue" EXACT [OBOL:automatic] synonym: "epididymus involuntary muscle" EXACT [OBOL:automatic] synonym: "epididymus non-striated muscle" EXACT [OBOL:automatic] synonym: "epididymus smooth muscle" EXACT [OBOL:automatic] synonym: "epididymus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of epididymis" EXACT [OBOL:automatic] synonym: "involuntary muscle of epididymus" EXACT [OBOL:automatic] synonym: "non-striated muscle of epididymis" EXACT [OBOL:automatic] synonym: "non-striated muscle of epididymus" EXACT [OBOL:automatic] synonym: "smooth muscle of epididymis" EXACT [OBOL:automatic] synonym: "smooth muscle of epididymus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of epididymis" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of epididymus" EXACT [OBOL:automatic] xref: MA:0001736 ! epididymis smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001301 ! part_of epididymis [Term] id: UBERON:0001602 name: medial rectus alt_id: UBERON:0004836 def: "The medial rectus muscle is a muscle in the orbit. As with most of the muscles of the orbit, it is innervated by the inferior division of the oculomotor nerve (Cranial Nerve III). This muscle shares an origin with several other extrinsic eye muscles, the anulus tendineus, or common tendon. It is the largest of the extraocular muscles and its only action is adduction of the eyeball. [WP,unvetted]." [Wikipedia:Medial_rectus_muscle] comment: Taxon notes (from VHOG): "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution." Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective, Third Edition (2001) Orlando Fla.: Harcourt College Publishers, p.331 [VHOG:0001127] subset: uberon_slim subset: vertebrate_core synonym: "medial rectus extraocular muscle" EXACT [MA:0001281] synonym: "medial rectus muscle" EXACT [] xref: FMA:49037 ! Medial rectus xref: TAO:0000301 ! medial rectus xref: ZFA:0000301 ! medial rectus xref: MA:0001281 ! medial rectus extraocular muscle xref: ncithesaurus:Medial_Rectus_Muscle ! Medial Rectus Muscle xref: VHOG:0001127 ! medial rectus extraocular muscle xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e8/Eyemuscles.png/200px-Eyemuscles.png is_a: UBERON:0006533 {source="MA"} ! rectus extraocular muscle relationship: part_of UBERON:0002376 ! muscle of head xref: SCTID:181151001 ! Entire medial rectus synonym: "musculus rectus medialis bulbi" RELATED LATIN [Wikipedia:Medial_rectus_muscle] relationship: innervated_by UBERON:0001643 {source="dbpedia", notes="inferior division of the oculomotor nerve"} ! oculomotor nerve xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Eyemuscles.png property_value: homology_notes "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0001127", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.331", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0582820 [Term] id: UBERON:0001603 name: lateral rectus extra-ocular muscle alt_id: UBERON:0004837 def: "The lateral rectus muscle is a muscle in the orbit. It is one of six extraocular muscles that control the movements of the eye (abduction in this case) and the only muscle innervated by the abducens nerve, cranial nerve VI. [WP,unvetted]." [Wikipedia:Lateral_rectus_muscle] synonym: "lateral rectus extraocular muscle" EXACT [MA:0001280] synonym: "lateral rectus muscle" EXACT [] synonym: "lateral rectus" EXACT [FMA:49038] synonym: "musculus rectus lateralis" EXACT [AAO:0010107] synonym: "M. rectus lateralis" EXACT [] subset: uberon_slim subset: vertebrate_core xref: FMA:49038 ! Lateral rectus xref: TAO:0000383 ! lateral rectus xref: ZFA:0000383 ! lateral rectus xref: MA:0001280 ! lateral rectus extraocular muscle xref: VHOG:0001129 ! lateral rectus extraocular muscle xref: AAO:0010107 ! musculus rectus lateralis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e8/Eyemuscles.png/200px-Eyemuscles.png is_a: UBERON:0006533 {source="MA"} ! rectus extraocular muscle xref: SCTID:181152008 ! Entire lateral rectus xref: ncithesaurus:Lateral_Rectus_Muscle ! Lateral Rectus Muscle relationship: innervated_by UBERON:0001646 {source="dbpedia"} ! abducens nerve synonym: "musculus rectus lateralis bulbi" RELATED LATIN [Wikipedia:Lateral_rectus_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Eyemuscles.png property_value: external_definition "Cranial nerve VI innervated; lateral in the rectus group.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010107", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: homology_notes "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0001129", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.331", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0582821 [Term] id: UBERON:0004848 name: respiratory system arterial endothelium def: "An endothelium of artery that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius arterial endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius artery endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of artery" EXACT [OBOL:automatic] synonym: "arterial endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "arterial endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "artery endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "artery endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of artery of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of artery of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system artery endothelium" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of artery" EXACT [OBOL:automatic] xref: MA:0001801 ! respiratory system arterial endothelium intersection_of: UBERON:0001917 ! endothelium of artery intersection_of: part_of UBERON:0001004 ! part_of respiratory system relationship: part_of UBERON:0003643 ! respiratory system arterial blood vessel relationship: part_of UBERON:0003469 {is_inferred="true", source="reference_0000032"} ! respiratory system artery relationship: part_of UBERON:0003504 {source="reference_0000032"} ! respiratory system blood vessel [Term] id: UBERON:0004849 name: respiratory system venous endothelium def: "An endothelium of vein that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius endothelium of vein" EXACT [OBOL:automatic] synonym: "apparatus respiratorius vein endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius venous endothelium" EXACT [OBOL:automatic] synonym: "endothelium of vein of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of vein of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of vein" EXACT [OBOL:automatic] synonym: "respiratory system vein endothelium" EXACT [OBOL:automatic] synonym: "vein endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "vein endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "venous endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "venous endothelium of respiratory system" EXACT [OBOL:automatic] xref: MA:0001811 ! respiratory system venous endothelium intersection_of: UBERON:0001919 ! endothelium of vein intersection_of: part_of UBERON:0001004 ! part_of respiratory system relationship: part_of UBERON:0003476 ! respiratory system venous blood vessel relationship: part_of UBERON:0003504 {source="reference_0000032"} ! respiratory system blood vessel [Term] id: UBERON:0004850 name: lymph node endothelium def: "An endothelium that is part of a lymph node [Automatically generated definition]." [OBOL:automatic] synonym: "endothelium of lymph node" EXACT [OBOL:automatic] xref: MA:0000741 ! lymph node endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000029 ! part_of lymph node [Term] id: UBERON:0004851 name: aorta endothelium def: "An endothelium that is part of an aorta [Automatically generated definition]." [OBOL:automatic] synonym: "adult aorta endothelium" EXACT [OBOL:automatic] synonym: "endothelium of adult aorta" EXACT [OBOL:automatic] synonym: "endothelium of aorta" EXACT [OBOL:automatic] synonym: "endothelium of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "endothelium of trunk of systemic arterial tree" EXACT [OBOL:automatic] synonym: "trunk of aortic tree endothelium" EXACT [OBOL:automatic] synonym: "trunk of systemic arterial tree endothelium" EXACT [OBOL:automatic] xref: MA:0000701 ! aorta endothelium xref: BTO:0000394 ! aorta endothelium xref: EFO:0002597 ! aorta endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000947 ! part_of aorta xref: ncithesaurus:Aorta_Endothelium ! Aorta Endothelium xref: UMLS:C1706824 [Term] id: UBERON:0004854 name: gastrointestinal system mesentery def: "A mesentery that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "digestive system mesentery" EXACT [OBOL:automatic] synonym: "mesentery of digestive system" EXACT [OBOL:automatic] synonym: "mesentery of gastrointestinal system" EXACT [OBOL:automatic] xref: MA:0001900 ! gastrointestinal system mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0005409 ! gastrointestinal system [Term] id: UBERON:0004857 name: skeletal muscle connective tissue synonym: "connective tissue of skeletal muscle" EXACT [OBOL:automatic] synonym: "connective tissue of skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "portion of connective tissue of skeletal muscle" EXACT [OBOL:automatic] synonym: "portion of connective tissue of skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle portion of connective tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle textus connectivus" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue connective tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue portion of connective tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of skeletal muscle" EXACT [OBOL:automatic] synonym: "textus connectivus of skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle interstitial tissue" RELATED [MA:0002868] synonym: "skeletal muscle interstitum" RELATED [MA:0002868] xref: MA:0002868 ! skeletal muscle connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: surrounds UBERON:0001134 ! skeletal muscle tissue def: "A connective tissue that surrounds a skeletal muscle tissue." [OBOL:automatic] [Term] id: UBERON:0004858 name: cellular cartilage xref: MA:0000105 ! cellular cartilage is_a: UBERON:0002418 ! cartilage tissue xref: SCTID:81997001 ! Cellular cartilage [Term] id: UBERON:0004859 name: eye gland def: "A gland that is part of a eye [Automatically generated definition]." [OBOL:automatic] comment: Example: harderian gland synonym: "gland of eye" EXACT [OBOL:automatic] xref: MA:0000267 ! eye gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000019 ! camera-type eye subset: organ_slim [Term] id: UBERON:0013645 name: gular gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0011154 ! gular region [Term] id: UBERON:0004863 name: thoracic sympathetic nerve trunk def: "A sympathetic nerve trunk that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "nerve trunk of sympathetic nervous system of thorax" EXACT [OBOL:automatic] synonym: "nerve trunk of sympathetic part of autonomic division of nervous system of thorax" EXACT [OBOL:automatic] synonym: "sympathetic nerve trunk of thorax" EXACT [OBOL:automatic] synonym: "sympathetic nervous system nerve trunk of thorax" EXACT [OBOL:automatic] synonym: "thorax nerve trunk of sympathetic nervous system" EXACT [OBOL:automatic] synonym: "thorax nerve trunk of sympathetic part of autonomic division of nervous system" EXACT [OBOL:automatic] synonym: "thorax sympathetic nerve trunk" EXACT [OBOL:automatic] synonym: "thorax sympathetic nervous system nerve trunk" EXACT [OBOL:automatic] synonym: "thoracic sympathetic trunk" RELATED [FMA:6262] xref: MA:0001165 ! thoracic sympathetic nerve trunk xref: FMA:6262 ! Thoracic sympathetic trunk intersection_of: UBERON:0004295 ! sympathetic nerve trunk intersection_of: part_of UBERON:0000915 ! part_of thorax xref: ncithesaurus:Thoracic_Sympathetic_Nerve_Trunk ! Thoracic Sympathetic Nerve Trunk synonym: "thoracic part of sympathetic trunk" EXACT [FMA:6262] synonym: "thoracic sympathetic chain" EXACT [FMA:6262] xref: UMLS:C1710393 [Term] id: UBERON:0003501 name: retina blood vessel def: "A blood vessel that is part of a retina [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of inner layer of eyeball" EXACT [OBOL:automatic] synonym: "blood vessel of retina" EXACT [OBOL:automatic] synonym: "retinal blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of tunica interna of eyeball" EXACT [OBOL:automatic] synonym: "inner layer of eyeball blood vessel" EXACT [OBOL:automatic] synonym: "tunica interna of eyeball blood vessel" EXACT [OBOL:automatic] xref: MA:0001317 ! retina blood vessel xref: GAID:509 ! retinal vessel xref: MESH:A07.231.611 ! retinal vessel (also: UBERON:0004864 'vasculature of retina') intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000966 ! retina relationship: part_of UBERON:0004864 ! vasculature of retina xref: SCTID:280692003 ! Entire blood vessel of retina xref: XAO:0004153 ! retinal blood vessel (also: UBERON:0004864 'vasculature of retina') [Term] id: UBERON:0004864 name: vasculature of retina def: "A vasculature that is part of a retina [Automatically generated definition]." [OBOL:automatic] synonym: "retina vasculature of camera-type eye" EXACT [GO:0061298] synonym: "retina vasculature" EXACT [GO:0061298] synonym: "retinal vasculature" EXACT [OBOL:automatic] synonym: "set of retinal blood vessels" EXACT [FMA:76552] synonym: "set of blood vessels of retina" EXACT [OBOL:automatic] synonym: "retinal blood vessels" EXACT [FMA:76552] synonym: "retinal blood vessels set" EXACT [FMA:76552] xref: FMA:76552 ! Set of retinal blood vessels xref: MESH:A07.231.611 ! retinal vessel (also: UBERON:0003501 'retina blood vessel') intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000966 ! retina synonym: "vasa sanguinea retinae" EXACT LATIN [FMA:TA, FMA:76552] xref: XAO:0004153 ! retinal blood vessel (also: UBERON:0003501 'retina blood vessel') [Term] id: UBERON:0004869 name: parietal organ namespace: uberon def: "A part of the epithalamus present in some animal species. The eye may be photoreceptive and is usually associated with the pineal gland, regulating circadian rhythmicity and hormone production for thermoregulation. The parietal eye is a part of the epithalamus, which can be divided into two major parts; the epiphysis (the pineal organ, or pineal gland if mostly endocrine) and the parietal organ (often called the parietal eye, or third eye if it is photoreceptive). It arises as an anterior evagination of the pineal organ or as a separate outgrowth of the roof of the diencephalon. In some species, it protrudes through the skull.[4] The parietal eye uses a different biochemical method of detecting light than rod cells or cone cells in a normal vertebrate eye[WP]." [Wikipedia:Parietal_eye] synonym: "parietal eye" EXACT [Wikipedia:Parietal_eye] synonym: "third eye" RELATED [Wikipedia:Parietal_eye] is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001899 ! epithalamus [Term] id: UBERON:0004889 name: lobar bronchus vasculature def: "Vasculature that is composed of the tubule structures that carry blood or lymph in the lungs" [LG:0012616] intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002183 ! lobar bronchus [Term] id: UBERON:0004891 name: obsolete lobar bronchus bronchiole is_obsolete: true comment: This class was obsoleted as it was generated from an incorrect inference from EMAPA [Term] id: UBERON:0003538 name: right lung bronchiole def: "A bronchiole that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole of right lung" EXACT [OBOL:automatic] synonym: "lobular bronchiole of right lung" EXACT [OBOL:automatic] synonym: "right lung lobular bronchiole" EXACT [OBOL:automatic] xref: MA:0001787 ! right lung bronchiole xref: ncithesaurus:Right_Lung_Bronchiole ! Right Lung Bronchiole intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0002167 ! right lung xref: SCTID:200089000 ! Entire bronchiole of right lung xref: UMLS:C0225670 [Term] id: UBERON:0003539 name: left lung bronchiole def: "A bronchiole that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole of left lung" EXACT [OBOL:automatic] synonym: "left lung lobular bronchiole" EXACT [OBOL:automatic] synonym: "lobular bronchiole of left lung" EXACT [OBOL:automatic] xref: MA:0001778 ! left lung bronchiole xref: ncithesaurus:Left_Lung_Bronchiole ! Left Lung Bronchiole xref: EMAPA:19000 ! bronchiole of lobar bronchus of left lung intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0002168 ! left lung xref: SCTID:200484003 ! Entire bronchiole of left lung xref: UMLS:C0225674 [Term] id: UBERON:0012055 name: left lung lower lobe bronchiole comment: Mouse has single left lobe intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0008953 ! lower lobe of left lung xref: EHDAA2:0000947 ! left lung caudal lobe bronchiole xref: SCTID:80548008 ! Entire bronchiole of left lower lobe synonym: "left lung caudal lobe bronchiole" EXACT [EHDAA2:0000947] synonym: "bronchiole of left lower lobe of lung" EXACT [] synonym: "bronchiole of left lower lobe" EXACT [] def: "A bronchiole that is part of a lower lobe of left lung." [OBOL:automatic] [Term] id: UBERON:0012056 name: left lung upper lobe bronchiole comment: Mouse has single left lobe intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0008952 ! upper lobe of left lung synonym: "bronchiole of left cranial lobe" EXACT [] synonym: "bronchiole of left upper lobe of lung" EXACT [] synonym: "bronchiole of left upper lobe" EXACT [] xref: EHDAA2:0000955 ! left lung cranial lobe bronchiole xref: SCTID:72426004 ! Entire bronchiole of left upper lobe synonym: "left lung cranial lobe bronchiole" EXACT [EHDAA2:0000955] def: "A bronchiole that is part of a upper lobe of left lung." [OBOL:automatic] [Term] id: UBERON:0005681 name: right lung upper lobe bronchiole xref: EHDAA2:0001749 ! right lung cranial lobe bronchiole xref: EMAPA:19006 ! bronchiole of cranial lobe xref: SCTID:84841004 ! Entire bronchiole of right upper lobe synonym: "right lung cranial lobe bronchiole" EXACT [EHDAA2:0001749] synonym: "bronchiole of right upper lobe of lung" EXACT [] synonym: "bronchiole of right upper lobe" EXACT [] intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0002170 ! upper lobe of right lung def: "A bronchiole that is part of a upper lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0012068 name: right lung middle lobe bronchiole xref: EMAPA:19008 ! bronchiole of lobar bronchus of middle lobe xref: SCTID:69714005 ! Entire bronchiole of right middle lobe synonym: "bronchiole of middle right lobe" EXACT [] synonym: "bronchiole of right middle lobe of lung" EXACT [] synonym: "bronchiole of right middle lobe" EXACT [] intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0002174 ! middle lobe of right lung def: "A bronchiole that is part of a middle lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0012059 name: right lung lower lobe bronchiole relationship: develops_from UBERON:0005640 {source="EHDAA2"} ! right lung caudal lobe epithelium intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0002171 ! lower lobe of right lung xref: EHDAA2:0004094 ! right lung caudal lobe bronchiole xref: EMAPA:19004 ! bronchiole of lobar bronchus of caudal lobe xref: SCTID:15215000 ! Entire bronchiole of right lower lobe synonym: "right lung caudal lobe bronchiole" EXACT [EHDAA2:0004094] synonym: "bronchiole of right cranial lobe" EXACT [] synonym: "bronchiole of right lower lobe of lung" EXACT [] synonym: "bronchiole of right lower lobe" EXACT [] def: "A bronchiole that is part of a lower lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0005682 name: right lung accessory lobe bronchiole xref: EHDAA2:0001733 ! right lung accessory lobe bronchiole xref: EMAPA:19002 ! bronchiole of lobar bronchus of accessory lobe intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0004890 ! right lung accessory lobe def: "A bronchiole that is part of a right lung accessory lobe." [OBOL:automatic] [Term] id: UBERON:0004892 name: lobar bronchus alveolar system def: "The lobar bronchus alveolar system is where molecules of oxygen and carbon dioxide are passively exchanged, by diffusion, between the gaseous environment and the blood in the lobar bronchus" [LG:0012622] is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002183 ! lobar bronchus [Term] id: UBERON:0004893 ! interalveolar septum name: interalveolar septum def: "A the thin septum that separates adjacent pulmonary alveoli, containing connective tissue constituents of the respiratory tissue and the capillary network of the blood supply of the lung." [LG:0012625, Wikipedia:Alveolar_septum] synonym: "alveolar septum" EXACT [UBERON:cjm] synonym: "septal bone" RELATED [BTO:0003149] synonym: "septum interalveolare" RELATED [BTO:0003149] xref: MA:0000421 ! interalveolar septum xref: BTO:0003149 ! interalveolar septum intersection_of: UBERON:0003037 ! septum intersection_of: adjacent_to UBERON:0002299 ! alveolus of lung relationship: part_of UBERON:0006524 ! alveolar system xref: ncithesaurus:Alveolar_Septum ! Alveolar Septum xref: UMLS:C1706784 [Term] id: UBERON:0005314 name: alveolar primary septum def: "A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms[GO]." [GO:0061143] comment: TODO - check UBERON:0004893 interalveolar septum is_a: UBERON:0000115 ! lung epithelium relationship: surrounds UBERON:0000116 ! lung saccule [Term] id: UBERON:0005315 name: alveolar secondary septum def: "A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule[GO]." [GO:0061144] comment: TODO - check UBERON:0004893 interalveolar septum is_a: UBERON:0000115 ! lung epithelium relationship: part_of UBERON:0000116 ! lung saccule [Term] id: UBERON:0004894 name: alveolar wall def: "A wall that contains the alveoli" [LG:0012626] synonym: "wall of pulmonary alveolus" EXACT [FMA:14117] synonym: "pulmonary alveolar wall" EXACT [FMA:14117] synonym: "pulmonary interalveolar septum" EXACT [FMA:14117] xref: MA:0002568 ! alveolar wall xref: FMA:14117 ! Wall of pulmonary alveolus xref: BTO:0002543 ! alveolar wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0002299 ! alveolus of lung xref: ncithesaurus:Alveolar_Wall ! Alveolar Wall xref: SCTID:361965008 ! Entire alveolar wall xref: UMLS:C0225695 [Term] id: UBERON:0004895 name: alveolar smooth muscle def: "Alveolar smooth muscle is a type of non-striated muscle, found within the walls of the alveolus" [LG:0012628] xref: MA:0002759 ! alveolar smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002299 ! alveolus of lung [Term] id: UBERON:0003404 name: lobar bronchus of right lung def: "A lobar bronchus that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "right lobar bronchus" EXACT [OBOL:automatic] synonym: "right lung lobar bronchus" EXACT [OBOL:automatic] synonym: "right lung secondary bronchus" EXACT [OBOL:automatic] synonym: "secondary bronchus of right lung" EXACT [OBOL:automatic] xref: EMAPA:17664 ! lobar bronchus of right lung xref: SCTID:245511004 ! Entire right lobar bronchus intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0002167 ! right lung relationship: part_of UBERON:0006518 {is_inferred="true", source="reference_0000032"} ! right lung lobe [Term] id: UBERON:0003405 name: lobar bronchus of left lung def: "A lobar bronchus that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "left lobar bronchus" EXACT [OBOL:automatic] synonym: "left lung lobar bronchus" EXACT [OBOL:automatic] synonym: "left lung secondary bronchus" EXACT [OBOL:automatic] synonym: "secondary bronchus of left lung" EXACT [OBOL:automatic] xref: EMAPA:17656 ! lobar bronchus of left lung xref: EMAPA:17388 ! lobar bronchus of left lung rudiment xref: SCTID:245510003 ! Entire left lobar bronchus intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0002168 ! left lung relationship: part_of UBERON:0008951 {is_inferred="true", source="reference_0000032"} ! left lung lobe [Term] id: UBERON:0005244 alt_id: UBERON:0012060 name: lobar bronchus of right lung cranial lobe def: "." [Wikipedia:Eparterial_bronchus] synonym: "right upper lobar bronchus" EXACT [FMA:7397] synonym: "right upper lobe bronchus" EXACT [FMA:7397] synonym: "eparterial bronchus" RELATED [Wikipedia:Eparterial_bronchus] synonym: "lobar bronchus of cranial lobe" BROAD [EMAPA:17992] synonym: "right superior lobar bronchus" EXACT [FMA:7397] synonym: "right lung cranial lobe lobar bronchus" EXACT [EHDAA2:0001752] xref: SCTID:181806003 ! Entire eparterial bronchus xref: SCTID:361956001 ! Entire bronchus of right upper lobe xref: FMA:7397 ! right superior lobar bronchus xref: EMAPA:17992 ! lobar bronchus of cranial lobe xref: VHOG:0000240 ! lobar bronchus of right lung cranial lobe xref: EHDAA2:0001752 ! right lung cranial lobe lobar bronchus intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0002170 ! upper lobe of right lung [Term] id: UBERON:0004896 name: right lung accessory lobe lobar bronchus def: "The right lung accessory lobe lobar bronchus is the major airway within the right lung accessory lobe that starts at the division of the bronchus on the right side and ends at the point of its own subdivision into tertiary or segmental bronchi" [LG:0012636] synonym: "lobar bronchus of accessory lobe" BROAD [EMAPA:17982] xref: VHOG:0000239 ! lobar bronchus of right lung accessory lobe xref: EHDAA2:0001736 ! right lung accessory lobe lobar bronchus xref: EMAPA:17982 ! lobar bronchus of accessory lobe intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0004890 ! right lung accessory lobe synonym: "lobar bronchus of right lung accessory lobe" EXACT [VHOG:0000239] [Term] id: UBERON:0005245 name: lobar bronchus of right lung caudal lobe def: "A lobar bronchus that is part of a lower lobe of right lung [Automatically generated definition]." [OBOL:automatic] synonym: "lobar bronchus of caudal lobe" EXACT [EMAPA:17987] xref: EMAPA:17987 ! lobar bronchus of caudal lobe xref: VHOG:0000250 ! lobar bronchus of the right lung caudal lobe xref: EHDAA2:0001744 ! right lung caudal lobe lobar bronchus intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0002171 ! lower lobe of right lung [Term] id: UBERON:0012063 name: lobar bronchus of right lung middle lobe synonym: "bronchus of right middle lobe" EXACT [FMA:7401] synonym: "middle lobe bronchus" EXACT [FMA:7401] intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0002174 ! middle lobe of right lung xref: FMA:7401 ! middle lobar bronchus synonym: "middle lobar bronchus" EXACT [FMA:7401] def: "A lobar bronchus that is part of a middle lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0012065 name: lobar bronchus of left lung upper lobe synonym: "bronchus of left upper lobe" EXACT [FMA:7423] synonym: "left upper lobar bronchus" EXACT [FMA:7423] synonym: "left upper lobe bronchus" EXACT [FMA:7423] intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0008952 ! upper lobe of left lung xref: FMA:7423 ! left superior lobar bronchus synonym: "left superior lobar bronchus" EXACT [FMA:7423] def: "A lobar bronchus that is part of a upper lobe of left lung." [OBOL:automatic] [Term] id: UBERON:0012066 name: lobar bronchus of left lung lower lobe synonym: "bronchus of left lower lobe" EXACT [FMA:7432] synonym: "left lower lobar bronchus" EXACT [FMA:7432] synonym: "left lower lobe bronchus" EXACT [FMA:7432] intersection_of: UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0008953 ! lower lobe of left lung xref: FMA:7432 ! left inferior lobar bronchus xref: SCTID:361961004 ! Entire bronchus of left lower lobe synonym: "left inferior lobar bronchus" EXACT [FMA:7432] def: "A lobar bronchus that is part of a lower lobe of left lung." [OBOL:automatic] [Term] id: UBERON:0006524 name: alveolar system def: "System pertaining to a bronchus and alveoli." [BTO:0000136] synonym: "bronchoalveolar system" RELATED [BTO:0000136] synonym: "pulmonary alveolar system" EXACT [MP:0010899] xref: MA:0000416 ! alveolar system xref: EMAPA:19003 ! alveolar system of bronchiole of lobar bronchus of accessory lobe xref: EMAPA:19005 ! alveolar system of bronchiole of lobar bronchus of caudal lobe xref: EMAPA:19007 ! alveolar system of bronchiole of lobar bronchus of cranial lobe xref: EMAPA:19009 ! alveolar system of bronchiole of lobar bronchus of middle lobe xref: BTO:0000136 ! bronchoalveolar system is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0006525 name: left lung alveolar system xref: MA:0001775 ! left lung alveolar system xref: EMAPA:19001 ! alveolar system of bronchiole of lobar bronchus of left lung is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002168 ! left lung relationship: part_of UBERON:0006524 ! alveolar system [Term] id: UBERON:0006526 name: right lung alveolar system xref: MA:0001784 ! right lung alveolar system is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002167 ! right lung relationship: part_of UBERON:0006524 ! alveolar system [Term] id: UBERON:0004897 name: right lung accessory lobe lobar bronchus mesenchyme def: "The right lung accessory lobe lobar bronchus mesenchyme is a type of tissue made up of loosely-packed mesenchymal cells in the right lung accessory lobe lobar bronchus" [LG:0012640] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003404 ! lobar bronchus of right lung intersection_of: part_of UBERON:0004890 ! right lung accessory lobe [Term] id: UBERON:0004898 name: obsolete right lung caudal lobe lobar bronchus mesenchyme is_obsolete: true [Term] id: UBERON:0004899 name: right lung cranial lobe lobar bronchus mesenchyme def: "The right lung cranial lobe lobar bronchus mesenchyme is a type of tissue made up of loosely-packed mesenchymal cells in the right lung cranial lobe lobar bronchus" [LG:0012659] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003404 ! lobar bronchus of right lung intersection_of: part_of UBERON:0002170 ! upper lobe of right lung [Term] id: UBERON:0004900 name: right lung middle lobe lobar bronchus mesenchyme def: "The right lung middle lobe lobar bronchus mesenchyme is a type of tissue made up of loosely-packed mesenchymal cells in the right lung middle lobe lobar bronchus" [LG:0012672] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003404 ! lobar bronchus of right lung intersection_of: part_of UBERON:0002174 ! right lung middle lobe [Term] id: UBERON:0004901 name: right lung lobar bronchus mesenchyme def: "The right lung lobar bronchus mesenchyme is a type of tissue made up of loosely-packed mesenchymal cells in the right lung lobar bronchus" [LG:0012681] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002183 ! lobar bronchus intersection_of: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0011289 name: pharyngobasilar fascia def: "The pharyngeal aponeurosis (or pharyngobasilar fascia, or fibrous coat), is situated between the mucous and muscular layers. It is thick above where the muscular fibers are wanting, and is firmly connected to the basilar portion of the occipital and the petrous portions of the temporal bones. As it descends it diminishes in thickness, and is gradually lost. It is strengthened posteriorly by a strong fibrous band, which is attached above to the pharyngeal spine on the under surface of the basilar portion of the occipital bone, and passes downward, forming a median raphe, which gives attachment to the Constrictores pharyngis." [Wikipedia:Pharyngobasilar_fascia] synonym: "pharyngeal aponeurosis" RELATED [Wikipedia:Pharyngobasilar_fascia] synonym: "pharyngeal aponeurosis" EXACT [FMA:55074] is_a: UBERON:0006614 {source="FMA"} ! aponeurosis intersection_of: UBERON:0006614 ! aponeurosis intersection_of: part_of UBERON:0001042 ! part_of pharynx xref: FMA:55074 ! pharyngobasilar fascia xref: SCTID:16675008 ! Pharyngobasilar fascia [Term] id: UBERON:0004924 name: submucosa of pharynx def: "The tissue underlying the tunica mucosa of the pharynx." [BTO:0002113] synonym: "pharyngobasilar fascia" RELATED [] synonym: "submucous coat of pharynx" RELATED [BTO:0002113] synonym: "submucous layer of pharynx" RELATED [BTO:0002113] synonym: "pharynx submucosa" EXACT [OBOL:automatic] synonym: "pharyngeal submucosa" EXACT [FMA:75144] synonym: "tela submucosa pharyngis" EXACT LATIN [BTO:0002113] xref: FMA:75144 ! Submucosa of pharynx intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001042 ! part_of pharynx xref: SCTID:19594009 ! Pharyngeal submucosa xref: BTO:0002113 ! tela submucosa pharyngis [Term] id: UBERON:0004925 name: submucosa of laryngopharynx def: "A submucosa that is part of a hypopharynx [Automatically generated definition]." [OBOL:automatic] synonym: "hypopharynx submucosa" EXACT [OBOL:automatic] synonym: "laryngeal pharynx submucosa" EXACT [OBOL:automatic] synonym: "laryngopharynx submucosa" EXACT [OBOL:automatic] synonym: "submucosa of hypopharynx" EXACT [OBOL:automatic] synonym: "submucosa of laryngeal pharynx" EXACT [OBOL:automatic] synonym: "tela submucosa (pars laryngea pharyngis)" EXACT [FMA:55072] xref: FMA:55072 ! Submucosa of laryngopharynx intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001051 ! part_of hypopharynx xref: SCTID:47496006 ! Submucosa of hypopharynx [Term] id: UBERON:0004926 name: submucosa of cystic duct def: "A submucosa that is part of a cystic duct [Automatically generated definition]." [OBOL:automatic] synonym: "cystic duct submucosa" EXACT [OBOL:automatic] synonym: "cystic ductal submucosa" EXACT [FMA:18013] xref: FMA:18013 ! Submucosa of cystic duct intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001152 ! part_of cystic duct [Term] id: UBERON:0004927 name: submucosa of cecum def: "A submucosa that is part of a cecum [Automatically generated definition]." [OBOL:automatic] synonym: "caecum submucosa" EXACT [OBOL:automatic] synonym: "cecum submucosa" EXACT [OBOL:automatic] synonym: "intestinum crassum caecum submucosa" EXACT [OBOL:automatic] synonym: "submucosa of caecum" EXACT [OBOL:automatic] synonym: "submucosa of intestinum crassum caecum" EXACT [OBOL:automatic] xref: FMA:14999 ! Submucosa of cecum intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001153 ! part_of cecum [Term] id: UBERON:0004928 name: submucosa of appendix def: "A submucosa that is part of an appendix [Automatically generated definition]." [OBOL:automatic] synonym: "appendix submucosa" EXACT [OBOL:automatic] synonym: "caecal appendix submucosa" EXACT [OBOL:automatic] synonym: "submucosa of caecal appendix" EXACT [OBOL:automatic] synonym: "submucosa of vermiform appendix" EXACT [OBOL:automatic] synonym: "submucosa of vermix" EXACT [OBOL:automatic] synonym: "vermiform appendix submucosa" EXACT [OBOL:automatic] synonym: "vermix submucosa" EXACT [OBOL:automatic] synonym: "appendiceal submucosa" EXACT [FMA:14992] xref: FMA:14992 ! Submucosa of appendix intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001154 ! part_of appendix xref: SCTID:86833001 ! Appendiceal submucosa [Term] id: UBERON:0004929 name: submucosa of ascending colon def: "A submucosa that is part of an ascending colon [Automatically generated definition]." [OBOL:automatic] synonym: "ascending colon submucosa" EXACT [OBOL:automatic] xref: FMA:15006 ! Submucosa of ascending colon intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001156 ! part_of ascending colon [Term] id: UBERON:0004930 name: submucosa of transverse colon def: "A submucosa that is part of a transverse colon [Automatically generated definition]." [OBOL:automatic] synonym: "transverse colon submucosa" EXACT [OBOL:automatic] xref: FMA:15013 ! Submucosa of transverse colon intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001157 ! part_of transverse colon [Term] id: UBERON:0004931 name: submucosa of descending colon def: "A submucosa that is part of a descending colon [Automatically generated definition]." [OBOL:automatic] synonym: "descending colon submucosa" EXACT [OBOL:automatic] xref: FMA:15020 ! Submucosa of descending colon intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001158 ! part_of descending colon [Term] id: UBERON:0004932 name: submucosa of sigmoid colon def: "A submucosa that is part of a sigmoid colon [Automatically generated definition]." [OBOL:automatic] synonym: "sigmoid colon submucosa" EXACT [OBOL:automatic] xref: FMA:15027 ! Submucosa of sigmoid colon intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001159 ! part_of sigmoid colon [Term] id: UBERON:0004933 name: submucosa of fundus of stomach def: "A submucosa that is part of a fundus of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "fundus gastricus (ventricularis) submucosa" EXACT [OBOL:automatic] synonym: "fundus of stomach submucosa" EXACT [OBOL:automatic] synonym: "stomach fundus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of fundus gastricus (ventricularis)" EXACT [OBOL:automatic] synonym: "submucosa of stomach fundus" EXACT [OBOL:automatic] xref: FMA:17058 ! Submucosa of fundus of stomach xref: EMAPA:27407 ! submucosa of fundus of stomach of gut xref: EMAPA:27153 ! submucosa of fundus of stomach of foregut intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001160 ! part_of fundus of stomach [Term] id: UBERON:0004934 name: submucosa of body of stomach def: "A submucosa that is part of a body of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "body of stomach submucosa" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) submucosa" EXACT [OBOL:automatic] synonym: "gastric body submucosa" EXACT [OBOL:automatic] synonym: "stomach body submucosa" EXACT [OBOL:automatic] synonym: "submucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "submucosa of gastric body" EXACT [OBOL:automatic] synonym: "submucosa of stomach body" EXACT [OBOL:automatic] xref: FMA:17059 ! Submucosa of body of stomach intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001161 ! part_of body of stomach [Term] id: UBERON:0004935 name: submucosa of cardia of stomach def: "A submucosa that is part of a cardia of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "cardia of stomach submucosa" EXACT [OBOL:automatic] synonym: "cardial part of stomach submucosa" EXACT [OBOL:automatic] synonym: "gastric cardia submucosa" EXACT [OBOL:automatic] synonym: "pars cardiaca (gaster) submucosa" EXACT [OBOL:automatic] synonym: "stomach cardiac region submucosa" EXACT [OBOL:automatic] synonym: "submucosa of cardial part of stomach" EXACT [OBOL:automatic] synonym: "submucosa of gastric cardia" EXACT [OBOL:automatic] synonym: "submucosa of pars cardiaca (gaster)" EXACT [OBOL:automatic] synonym: "submucosa of stomach cardiac region" EXACT [OBOL:automatic] xref: FMA:17457 ! Submucosa of cardia of stomach intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001162 ! part_of cardia of stomach [Term] id: UBERON:0004936 name: submucosa of pyloric antrum def: "A submucosa that is part of a pyloric antrum [Automatically generated definition]." [OBOL:automatic] synonym: "antrum of stomach submucosa" EXACT [OBOL:automatic] synonym: "pyloric antrum submucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum submucosa" EXACT [OBOL:automatic] synonym: "submucosa of antrum of stomach" EXACT [OBOL:automatic] synonym: "submucosa of stomach pyloric antrum" EXACT [OBOL:automatic] xref: FMA:17060 ! Submucosa of pyloric antrum intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001165 ! part_of pyloric antrum [Term] id: UBERON:0004937 name: submucosa of pylorus def: "A submucosa that is part of a pylorus [Automatically generated definition]." [OBOL:automatic] synonym: "pylorus submucosa" EXACT [FMA:17462] synonym: "pyloric submucosa" EXACT [] synonym: "pyloric part of stomach submucosa" EXACT [OBOL:automatic] synonym: "pylorus submucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric region submucosa" EXACT [OBOL:automatic] synonym: "submucosa of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "submucosa of stomach pyloric region" EXACT [OBOL:automatic] xref: FMA:17462 ! Submucosa of pylorus xref: EMAPA:27201 ! submucosa of pyloric region of stomach of foregut xref: EMAPA:27503 ! submucosa of pyloric region of stomach of gut intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001166 ! part_of pylorus [Term] id: UBERON:0004938 name: submucosa of biliary tree def: "A submucosa that is part of a biliary tree [Automatically generated definition]." [OBOL:automatic] synonym: "biliary tract submucosa" EXACT [OBOL:automatic] synonym: "biliary tree submucosa" EXACT [OBOL:automatic] synonym: "submucosa of biliary tract" EXACT [OBOL:automatic] xref: FMA:18009 ! Submucosa of biliary tree intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001173 ! part_of biliary tree [Term] id: UBERON:0004939 name: submucosa of common bile duct def: "A submucosa that is part of a common bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "common bile duct submucosa" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) submucosa" EXACT [OBOL:automatic] synonym: "submucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "common bile ductal submucosa" EXACT [FMA:18011] xref: FMA:18011 ! Submucosa of common bile duct intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001174 ! part_of common bile duct [Term] id: UBERON:0004940 name: submucosa of common hepatic duct def: "A submucosa that is part of a common hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "common hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "submucosa of hepatic duct" EXACT [OBOL:automatic] synonym: "common hepatic ductal submucosa" EXACT [FMA:18014] xref: FMA:18014 ! Submucosa of common hepatic duct intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001175 ! part_of common hepatic duct [Term] id: UBERON:0004941 name: submucosa of right hepatic duct def: "A submucosa that is part of a right hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "right hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "right hepatic ductal submucosa" EXACT [FMA:18015] xref: FMA:18015 ! Submucosa of right hepatic duct intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001176 ! part_of right hepatic duct [Term] id: UBERON:0004942 name: submucosa of left hepatic duct def: "A submucosa that is part of a left hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "left hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "left hepatic ductal submucosa" EXACT [FMA:18017] xref: FMA:18017 ! Submucosa of left hepatic duct intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001177 ! part_of left hepatic duct [Term] id: UBERON:0004943 name: submucosa of urinary bladder def: "The submucous layer of the wall of the urinary bladder." [BTO:0002117] synonym: "bladder submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bladder" EXACT [OBOL:automatic] synonym: "urinary bladder submucosa" EXACT [OBOL:automatic] synonym: "submucous layer of urinary bladder" RELATED [BTO:0002117] synonym: "tela submucosa vesicae urinariae" EXACT [BTO:0002117] xref: FMA:15929 ! Submucosa of urinary bladder intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001255 ! part_of urinary bladder synonym: "tela submucosa vesicae" EXACT LATIN [FMA:TA, FMA:15929] xref: SCTID:88384001 ! Submucosa of urinary bladder xref: BTO:0002117 ! tela submucosa vesicae urinariae relationship: part_of UBERON:0001256 {source="reference_0000032"} ! wall of urinary bladder [Term] id: UBERON:0011298 name: submucosa of uterine tube def: "The submucous layer of the wall of the uterine tube." [BTO:0002116] synonym: "submucous layer of uterine tube" RELATED [BTO:0002116] synonym: "uterine submucosa" RELATED [] synonym: "tela submucosa tubae uterinae" EXACT LATIN [BTO:0002116] synonym: "submucosa of fallopian tube" EXACT [] intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0003889 ! part_of fallopian tube xref: BTO:0002116 ! tela submucosa tubae uterinae xref: SCTID:245489008 ! Uterine submucosa [Term] id: UBERON:0004944 name: submucosa of trigone of urinary bladder def: "A submucosa that is part of a trigone of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "Lieutaud ' s trigone submucosa" EXACT [OBOL:automatic] synonym: "deep trigone submucosa" EXACT [OBOL:automatic] synonym: "submucosa of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "submucosa of deep trigone" EXACT [OBOL:automatic] synonym: "submucosa of trigone of bladder" EXACT [OBOL:automatic] synonym: "submucosa of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "submucosa of vesical trigone" EXACT [OBOL:automatic] synonym: "trigone of bladder submucosa" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder submucosa" EXACT [OBOL:automatic] synonym: "urinary bladder trigone submucosa" EXACT [OBOL:automatic] synonym: "vesical trigone submucosa" EXACT [OBOL:automatic] xref: FMA:17852 ! Submucosa of trigone of urinary bladder intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001257 ! part_of trigone of urinary bladder [Term] id: UBERON:0004945 name: submucosa of neck of urinary bladder def: "A submucosa that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck submucosa" EXACT [OBOL:automatic] synonym: "neck of bladder submucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bladder neck" EXACT [OBOL:automatic] synonym: "submucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "submucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "submucosa of vesical neck" EXACT [OBOL:automatic] synonym: "urinary bladder neck submucosa" EXACT [OBOL:automatic] synonym: "vesical neck submucosa" EXACT [OBOL:automatic] xref: FMA:17851 ! Submucosa of neck of urinary bladder intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001258 ! part_of neck of urinary bladder [Term] id: UBERON:0004946 name: submucosa of ileum def: "A submucosa that is part of a ileum [Automatically generated definition]." [OBOL:automatic] synonym: "ileum submucosa" EXACT [OBOL:automatic] synonym: "ileal submucosa" EXACT [FMA:14957] xref: FMA:14957 ! Submucosa of ileum intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002116 ! part_of ileum xref: SCTID:65374006 ! Ileal submucosa [Term] id: UBERON:0004947 name: submucosa of right main bronchus def: "A submucosa that is part of a right main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "right bronchus submucosa" EXACT [OBOL:automatic] synonym: "right main bronchus submucosa" EXACT [OBOL:automatic] synonym: "right principal bronchus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of right bronchus" EXACT [OBOL:automatic] synonym: "submucosa of right principal bronchus" EXACT [OBOL:automatic] synonym: "right main bronchial submucosa" EXACT [FMA:13139] xref: FMA:13139 ! Submucosa of right main bronchus intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002177 ! part_of right main bronchus [Term] id: UBERON:0004948 name: submucosa of left main bronchus def: "A submucosa that is part of a left main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "left bronchus submucosa" EXACT [OBOL:automatic] synonym: "left main bronchus submucosa" EXACT [OBOL:automatic] synonym: "left principal bronchus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of left bronchus" EXACT [OBOL:automatic] synonym: "submucosa of left principal bronchus" EXACT [OBOL:automatic] synonym: "left main bronchial submucosa" EXACT [FMA:13140] xref: FMA:13140 ! Submucosa of left main bronchus intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002178 ! part_of left main bronchus [Term] id: UBERON:0004949 name: submucosa of main bronchus def: "A submucosa that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchus principalis submucosa" EXACT [OBOL:automatic] synonym: "main bronchus submucosa" EXACT [OBOL:automatic] synonym: "primary bronchus submucosa" EXACT [OBOL:automatic] synonym: "principal bronchus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bronchus principalis" EXACT [OBOL:automatic] synonym: "submucosa of primary bronchus" EXACT [OBOL:automatic] synonym: "submucosa of principal bronchus" EXACT [OBOL:automatic] synonym: "main bronchial submucosa" EXACT [FMA:13118] xref: FMA:13118 ! Submucosa of main bronchus intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002182 ! part_of main bronchus [Term] id: UBERON:0004950 name: submucosa of lobar bronchus def: "A submucosa that is part of a lobar bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "lobar bronchus submucosa" EXACT [OBOL:automatic] synonym: "secondary bronchus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of secondary bronchus" EXACT [OBOL:automatic] synonym: "lobar bronchial submucosa" EXACT [FMA:62669] xref: FMA:62669 ! Submucosa of lobar bronchus intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002183 ! part_of lobar bronchus [Term] id: UBERON:0004951 name: submucosa of segmental bronchus def: "A submucosa that is part of a segmental bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "segmental bronchus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of tertiary bronchus" EXACT [OBOL:automatic] synonym: "tertiary bronchus submucosa" EXACT [OBOL:automatic] synonym: "segmental bronchial submucosa" EXACT [FMA:62670] xref: FMA:62670 ! Submucosa of segmental bronchus intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002184 ! part_of segmental bronchus [Term] id: UBERON:0004952 name: submucosa of bronchiole def: "A submucosa that is part of a bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole submucosa" EXACT [OBOL:automatic] synonym: "lobular bronchiole submucosa" EXACT [OBOL:automatic] synonym: "submucosa of lobular bronchiole" EXACT [OBOL:automatic] xref: FMA:62775 ! Submucosa of bronchiole intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002186 ! part_of bronchiole [Term] id: UBERON:0012651 name: mucosa of gastroduodenal junction intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0012650 ! gastroduodenal junction relationship: part_of UBERON:0001199 ! mucosa of stomach synonym: "gastroduodenal mucosa" EXACT [BTO:0005415] xref: BTO:0005415 ! gastroduodenal mucosa [Term] id: UBERON:0004980 name: mucosa of ureter def: "A mucosa that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of ureter" EXACT [OBOL:automatic] synonym: "ureter mucosa" EXACT [OBOL:automatic] synonym: "ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "ureter mucous membrane" EXACT [OBOL:automatic] synonym: "ureter organ mucosa" EXACT [OBOL:automatic] synonym: "mucosal layer of ureter" EXACT [FMA:15894] synonym: "tunica mucosa (ureter)" EXACT [FMA:15894] synonym: "ureteral mucosa" EXACT [FMA:15894] synonym: "ureteric mucosa" EXACT [FMA:15894] xref: FMA:15894 ! Mucosa of ureter intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000056 ! part_of ureter synonym: "tunica mucosa ureteris" EXACT LATIN [FMA:TA, FMA:15894] xref: galen:MucousMembraneOfUreter xref: SCTID:40476001 ! Mucous membrane of ureter relationship: part_of UBERON:0009916 {source="reference_0000032"} ! wall of ureter [Term] id: UBERON:0004982 name: mucosa of epiglottis def: "A mucosa that is part of a epiglottis [Automatically generated definition]." [OBOL:automatic] synonym: "epiglottis mucosa" EXACT [OBOL:automatic] synonym: "epiglottis mucosa of organ" EXACT [OBOL:automatic] synonym: "epiglottis mucous membrane" EXACT [OBOL:automatic] synonym: "epiglottis organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of epiglottis" EXACT [OBOL:automatic] synonym: "mucous membrane of epiglottis" EXACT [OBOL:automatic] synonym: "organ mucosa of epiglottis" EXACT [OBOL:automatic] xref: FMA:64015 ! Mucosa of epiglottis intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000388 ! part_of epiglottis xref: SCTID:156751001 ! Entire mucous membrane of epiglottis [Term] id: UBERON:0004983 name: mucosa of vagina def: "A mucosa that is part of a vagina [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of vagina" EXACT [OBOL:automatic] synonym: "mucous membrane of vagina" EXACT [OBOL:automatic] synonym: "organ mucosa of vagina" EXACT [OBOL:automatic] synonym: "vagina mucosa" EXACT [OBOL:automatic] synonym: "vagina mucosa of organ" EXACT [OBOL:automatic] synonym: "vagina mucous membrane" EXACT [OBOL:automatic] synonym: "vagina organ mucosa" EXACT [OBOL:automatic] synonym: "vaginal mucosa" EXACT [FMA:19975] xref: FMA:19975 ! Mucosa of vagina intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000996 ! part_of vagina synonym: "tunica mucosa vaginae" EXACT LATIN [FMA:TA, FMA:19975] xref: SCTID:362245006 ! Entire vaginal mucous membrane [Term] id: UBERON:0004984 name: mucosa of seminal vesicle def: "A mucosa that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of seminal gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of seminal vesicle" EXACT [OBOL:automatic] synonym: "mucosa of seminal gland" EXACT [OBOL:automatic] synonym: "mucous membrane of seminal gland" EXACT [OBOL:automatic] synonym: "mucous membrane of seminal vesicle" EXACT [OBOL:automatic] synonym: "organ mucosa of seminal gland" EXACT [OBOL:automatic] synonym: "organ mucosa of seminal vesicle" EXACT [OBOL:automatic] synonym: "seminal gland mucosa" EXACT [OBOL:automatic] synonym: "seminal gland mucosa of organ" EXACT [OBOL:automatic] synonym: "seminal gland mucous membrane" EXACT [OBOL:automatic] synonym: "seminal gland organ mucosa" EXACT [OBOL:automatic] synonym: "seminal vesicle mucosa" EXACT [OBOL:automatic] synonym: "seminal vesicle mucosa of organ" EXACT [OBOL:automatic] synonym: "seminal vesicle mucous membrane" EXACT [OBOL:automatic] synonym: "seminal vesicle organ mucosa" EXACT [OBOL:automatic] xref: FMA:19405 ! Mucosa of seminal vesicle intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000998 ! part_of seminal vesicle synonym: "tunica mucosa glandulae vesiculosae" EXACT LATIN [FMA:TA, FMA:19405] xref: SCTID:252260007 ! Entire mucosa of seminal vesicle [Term] id: UBERON:0004985 name: mucosa of ejaculatory duct def: "A mucosa that is part of a ejaculatory duct [Automatically generated definition]." [OBOL:automatic] synonym: "ejaculatory duct mucosa" EXACT [OBOL:automatic] synonym: "ejaculatory duct mucosa of organ" EXACT [OBOL:automatic] synonym: "ejaculatory duct mucous membrane" EXACT [OBOL:automatic] synonym: "ejaculatory duct organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of ejaculatory duct" EXACT [OBOL:automatic] synonym: "mucous membrane of ejaculatory duct" EXACT [OBOL:automatic] synonym: "organ mucosa of ejaculatory duct" EXACT [OBOL:automatic] synonym: "ejaculatory ductal mucosa" EXACT [FMA:19373] xref: FMA:19373 ! Mucosa of ejaculatory duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000999 ! part_of ejaculatory duct [Term] id: UBERON:0004986 name: mucosa of deferent duct def: "A mucosa that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] synonym: "deferent duct mucosa" EXACT [OBOL:automatic] synonym: "deferent duct mucosa of organ" EXACT [OBOL:automatic] synonym: "deferent duct mucous membrane" EXACT [OBOL:automatic] synonym: "deferent duct organ mucosa" EXACT [OBOL:automatic] synonym: "ductus deferens mucosa" EXACT [OBOL:automatic] synonym: "ductus deferens mucosa of organ" EXACT [OBOL:automatic] synonym: "ductus deferens mucous membrane" EXACT [OBOL:automatic] synonym: "ductus deferens organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of ductus deferens" EXACT [OBOL:automatic] synonym: "mucosa of organ of deferent duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of ductus deferens" EXACT [OBOL:automatic] synonym: "mucosa of organ of sperm duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of vas deferen" EXACT [OBOL:automatic] synonym: "mucosa of organ of vas deferens" EXACT [OBOL:automatic] synonym: "mucosa of sperm duct" EXACT [OBOL:automatic] synonym: "mucosa of vas deferen" EXACT [OBOL:automatic] synonym: "mucosa of vas deferens" EXACT [OBOL:automatic] synonym: "mucous membrane of deferent duct" EXACT [OBOL:automatic] synonym: "mucous membrane of ductus deferens" EXACT [OBOL:automatic] synonym: "mucous membrane of sperm duct" EXACT [OBOL:automatic] synonym: "mucous membrane of vas deferen" EXACT [OBOL:automatic] synonym: "mucous membrane of vas deferens" EXACT [OBOL:automatic] synonym: "organ mucosa of deferent duct" EXACT [OBOL:automatic] synonym: "organ mucosa of ductus deferens" EXACT [OBOL:automatic] synonym: "organ mucosa of sperm duct" EXACT [OBOL:automatic] synonym: "organ mucosa of vas deferen" EXACT [OBOL:automatic] synonym: "organ mucosa of vas deferens" EXACT [OBOL:automatic] synonym: "sperm duct mucosa" EXACT [OBOL:automatic] synonym: "sperm duct mucosa of organ" EXACT [OBOL:automatic] synonym: "sperm duct mucous membrane" EXACT [OBOL:automatic] synonym: "sperm duct organ mucosa" EXACT [OBOL:automatic] synonym: "vas deferen mucosa" EXACT [OBOL:automatic] synonym: "vas deferen mucosa of organ" EXACT [OBOL:automatic] synonym: "vas deferen mucous membrane" EXACT [OBOL:automatic] synonym: "vas deferen organ mucosa" EXACT [OBOL:automatic] synonym: "vas deferens mucosa" EXACT [OBOL:automatic] synonym: "vas deferens mucosa of organ" EXACT [OBOL:automatic] synonym: "vas deferens mucous membrane" EXACT [OBOL:automatic] synonym: "vas deferens organ mucosa" EXACT [OBOL:automatic] synonym: "deferent ductal mucosa" EXACT [FMA:19240] synonym: "tunica mucosa (ductus deferens)" EXACT [FMA:19240] xref: FMA:19240 ! Mucosa of deferent duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001000 ! part_of vas deferens synonym: "tunica mucosa ductus deferentis" EXACT LATIN [FMA:TA, FMA:19240] xref: SCTID:299626000 ! Entire mucosa of vas deferens [Term] id: UBERON:0004987 name: mucosa of laryngopharynx def: "A mucosa that is part of a hypopharynx [Automatically generated definition]." [OBOL:automatic] synonym: "hypopharynx mucosa" EXACT [OBOL:automatic] synonym: "hypopharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "hypopharynx mucous membrane" EXACT [OBOL:automatic] synonym: "hypopharynx organ mucosa" EXACT [OBOL:automatic] synonym: "laryngeal pharynx mucosa" EXACT [OBOL:automatic] synonym: "laryngeal pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "laryngeal pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "laryngeal pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "laryngopharynx mucosa" EXACT [OBOL:automatic] synonym: "laryngopharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "laryngopharynx mucous membrane" EXACT [OBOL:automatic] synonym: "laryngopharynx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of hypopharynx" EXACT [OBOL:automatic] synonym: "mucosa of laryngeal pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of hypopharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of laryngeal pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of laryngopharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of hypopharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of laryngeal pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of laryngopharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of hypopharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of laryngeal pharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of laryngopharynx" EXACT [OBOL:automatic] xref: FMA:55030 ! Mucosa of laryngopharynx intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001051 ! part_of hypopharynx xref: SCTID:362126008 ! Entire mucous membrane of hypopharynx [Term] id: UBERON:0004988 name: mucosa of cystic duct def: "A mucosa that is part of a cystic duct [Automatically generated definition]." [OBOL:automatic] synonym: "cystic duct mucosa" EXACT [OBOL:automatic] synonym: "cystic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "cystic duct mucous membrane" EXACT [OBOL:automatic] synonym: "cystic duct organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of cystic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of cystic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of cystic duct" EXACT [OBOL:automatic] synonym: "cystic ductal mucosa" EXACT [FMA:14690] xref: FMA:14690 ! Mucosa of cystic duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001152 ! part_of cystic duct [Term] id: UBERON:0004989 name: mucosa of appendix def: "A mucosa that is part of an appendix [Automatically generated definition]." [OBOL:automatic] synonym: "appendix mucosa" EXACT [OBOL:automatic] synonym: "appendix mucosa of organ" EXACT [OBOL:automatic] synonym: "appendix mucous membrane" EXACT [OBOL:automatic] synonym: "appendix organ mucosa" EXACT [OBOL:automatic] synonym: "caecal appendix mucosa" EXACT [OBOL:automatic] synonym: "caecal appendix mucosa of organ" EXACT [OBOL:automatic] synonym: "caecal appendix mucous membrane" EXACT [OBOL:automatic] synonym: "caecal appendix organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of caecal appendix" EXACT [OBOL:automatic] synonym: "mucosa of organ of appendix" EXACT [OBOL:automatic] synonym: "mucosa of organ of caecal appendix" EXACT [OBOL:automatic] synonym: "mucosa of organ of vermiform appendix" EXACT [OBOL:automatic] synonym: "mucosa of organ of vermix" EXACT [OBOL:automatic] synonym: "mucosa of vermiform appendix" EXACT [OBOL:automatic] synonym: "mucosa of vermix" EXACT [OBOL:automatic] synonym: "mucous membrane of appendix" EXACT [OBOL:automatic] synonym: "mucous membrane of caecal appendix" EXACT [OBOL:automatic] synonym: "mucous membrane of vermiform appendix" EXACT [OBOL:automatic] synonym: "mucous membrane of vermix" EXACT [OBOL:automatic] synonym: "organ mucosa of appendix" EXACT [OBOL:automatic] synonym: "organ mucosa of caecal appendix" EXACT [OBOL:automatic] synonym: "organ mucosa of vermiform appendix" EXACT [OBOL:automatic] synonym: "organ mucosa of vermix" EXACT [OBOL:automatic] synonym: "vermiform appendix mucosa" EXACT [OBOL:automatic] synonym: "vermiform appendix mucosa of organ" EXACT [OBOL:automatic] synonym: "vermiform appendix mucous membrane" EXACT [OBOL:automatic] synonym: "vermiform appendix organ mucosa" EXACT [OBOL:automatic] synonym: "vermix mucosa" EXACT [OBOL:automatic] synonym: "vermix mucosa of organ" EXACT [OBOL:automatic] synonym: "vermix mucous membrane" EXACT [OBOL:automatic] synonym: "vermix organ mucosa" EXACT [OBOL:automatic] synonym: "appendiceal mucous membrane" EXACT [FMA:14991] xref: FMA:14991 ! Mucosa of appendix intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001154 ! part_of appendix xref: SCTID:362155000 ! Entire appendiceal mucous membrane [Term] id: UBERON:0004990 name: mucosa of ascending colon def: "A mucosa that is part of an ascending colon [Automatically generated definition]." [OBOL:automatic] synonym: "ascending colon mucosa" EXACT [OBOL:automatic] synonym: "ascending colon mucosa of organ" EXACT [OBOL:automatic] synonym: "ascending colon mucous membrane" EXACT [OBOL:automatic] synonym: "ascending colon organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of ascending colon" EXACT [OBOL:automatic] synonym: "mucous membrane of ascending colon" EXACT [OBOL:automatic] synonym: "organ mucosa of ascending colon" EXACT [OBOL:automatic] xref: FMA:15005 ! Mucosa of ascending colon intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001156 ! part_of ascending colon [Term] id: UBERON:0004991 name: mucosa of transverse colon def: "A mucosa that is part of a transverse colon [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of transverse colon" EXACT [OBOL:automatic] synonym: "mucous membrane of transverse colon" EXACT [OBOL:automatic] synonym: "organ mucosa of transverse colon" EXACT [OBOL:automatic] synonym: "transverse colon mucosa" EXACT [OBOL:automatic] synonym: "transverse colon mucosa of organ" EXACT [OBOL:automatic] synonym: "transverse colon mucous membrane" EXACT [OBOL:automatic] synonym: "transverse colon organ mucosa" EXACT [OBOL:automatic] xref: FMA:15012 ! Mucosa of transverse colon intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001157 ! part_of transverse colon [Term] id: UBERON:0004992 name: mucosa of descending colon def: "A mucosa that is part of a descending colon [Automatically generated definition]." [OBOL:automatic] synonym: "descending colon mucosa" EXACT [OBOL:automatic] synonym: "descending colon mucosa of organ" EXACT [OBOL:automatic] synonym: "descending colon mucous membrane" EXACT [OBOL:automatic] synonym: "descending colon organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of descending colon" EXACT [OBOL:automatic] synonym: "mucous membrane of descending colon" EXACT [OBOL:automatic] synonym: "organ mucosa of descending colon" EXACT [OBOL:automatic] xref: FMA:15019 ! Mucosa of descending colon intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001158 ! part_of descending colon [Term] id: UBERON:0004993 name: mucosa of sigmoid colon def: "A mucosa that is part of a sigmoid colon [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of sigmoid colon" EXACT [OBOL:automatic] synonym: "mucous membrane of sigmoid colon" EXACT [OBOL:automatic] synonym: "organ mucosa of sigmoid colon" EXACT [OBOL:automatic] synonym: "sigmoid colon mucosa" EXACT [OBOL:automatic] synonym: "sigmoid colon mucosa of organ" EXACT [OBOL:automatic] synonym: "sigmoid colon mucous membrane" EXACT [OBOL:automatic] synonym: "sigmoid colon organ mucosa" EXACT [OBOL:automatic] xref: FMA:15026 ! Mucosa of sigmoid colon intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001159 ! part_of sigmoid colon [Term] id: UBERON:0004994 name: mucosa of fundus of stomach def: "A mucosa that is part of a fundus of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "fundus gastricus (ventricularis) mucosa" EXACT [OBOL:automatic] synonym: "fundus gastricus (ventricularis) mucosa of organ" EXACT [OBOL:automatic] synonym: "fundus gastricus (ventricularis) mucous membrane" EXACT [OBOL:automatic] synonym: "fundus gastricus (ventricularis) organ mucosa" EXACT [OBOL:automatic] synonym: "fundus of stomach mucosa" EXACT [OBOL:automatic] synonym: "fundus of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "fundus of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "fundus of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of fundus gastricus (ventricularis)" EXACT [OBOL:automatic] synonym: "mucosa of organ of fundus gastricus (ventricularis)" EXACT [OBOL:automatic] synonym: "mucosa of organ of fundus of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach fundus" EXACT [OBOL:automatic] synonym: "mucosa of stomach fundus" EXACT [OBOL:automatic] synonym: "mucous membrane of fundus gastricus (ventricularis)" EXACT [OBOL:automatic] synonym: "mucous membrane of fundus of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach fundus" EXACT [OBOL:automatic] synonym: "organ mucosa of fundus gastricus (ventricularis)" EXACT [OBOL:automatic] synonym: "organ mucosa of fundus of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach fundus" EXACT [OBOL:automatic] synonym: "stomach fundus mucosa" EXACT [OBOL:automatic] synonym: "stomach fundus mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach fundus mucous membrane" EXACT [OBOL:automatic] synonym: "stomach fundus organ mucosa" EXACT [OBOL:automatic] xref: FMA:17053 ! Mucosa of fundus of stomach intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001160 ! part_of fundus of stomach [Term] id: UBERON:0004995 name: mucosa of body of stomach def: "A mucosa that is part of a body of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "body of stomach mucosa" EXACT [OBOL:automatic] synonym: "body of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "body of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "body of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) mucosa" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) mucosa of organ" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) mucous membrane" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) organ mucosa" EXACT [OBOL:automatic] synonym: "gastric body mucosa" EXACT [OBOL:automatic] synonym: "gastric body mucosa of organ" EXACT [OBOL:automatic] synonym: "gastric body mucous membrane" EXACT [OBOL:automatic] synonym: "gastric body organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "mucosa of gastric body" EXACT [OBOL:automatic] synonym: "mucosa of organ of body of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "mucosa of organ of gastric body" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach body" EXACT [OBOL:automatic] synonym: "mucosa of stomach body" EXACT [OBOL:automatic] synonym: "mucous membrane of body of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "mucous membrane of gastric body" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach body" EXACT [OBOL:automatic] synonym: "organ mucosa of body of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "organ mucosa of gastric body" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach body" EXACT [OBOL:automatic] synonym: "stomach body mucosa" EXACT [OBOL:automatic] synonym: "stomach body mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach body mucous membrane" EXACT [OBOL:automatic] synonym: "stomach body organ mucosa" EXACT [OBOL:automatic] xref: FMA:17054 ! Mucosa of body of stomach intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001161 ! part_of body of stomach [Term] id: UBERON:0004996 name: mucosa of cardia of stomach def: "A mucosa that is part of a cardia of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "cardia of stomach mucosa" EXACT [OBOL:automatic] synonym: "cardia of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "cardia of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "cardia of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "cardial part of stomach mucosa" EXACT [OBOL:automatic] synonym: "cardial part of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "cardial part of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "cardial part of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "gastric cardia mucosa" EXACT [OBOL:automatic] synonym: "gastric cardia mucosa of organ" EXACT [OBOL:automatic] synonym: "gastric cardia mucous membrane" EXACT [OBOL:automatic] synonym: "gastric cardia organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of cardial part of stomach" EXACT [OBOL:automatic] synonym: "mucosa of gastric cardia" EXACT [OBOL:automatic] synonym: "mucosa of organ of cardia of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of cardial part of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of gastric cardia" EXACT [OBOL:automatic] synonym: "mucosa of organ of pars cardiaca (gaster)" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach cardiac region" EXACT [OBOL:automatic] synonym: "mucosa of pars cardiaca (gaster)" EXACT [OBOL:automatic] synonym: "mucosa of stomach cardiac region" EXACT [OBOL:automatic] synonym: "mucous membrane of cardia of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of cardial part of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of gastric cardia" EXACT [OBOL:automatic] synonym: "mucous membrane of pars cardiaca (gaster)" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach cardiac region" EXACT [OBOL:automatic] synonym: "organ mucosa of cardia of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of cardial part of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of gastric cardia" EXACT [OBOL:automatic] synonym: "organ mucosa of pars cardiaca (gaster)" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach cardiac region" EXACT [OBOL:automatic] synonym: "pars cardiaca (gaster) mucosa" EXACT [OBOL:automatic] synonym: "pars cardiaca (gaster) mucosa of organ" EXACT [OBOL:automatic] synonym: "pars cardiaca (gaster) mucous membrane" EXACT [OBOL:automatic] synonym: "pars cardiaca (gaster) organ mucosa" EXACT [OBOL:automatic] synonym: "stomach cardiac region mucosa" EXACT [OBOL:automatic] synonym: "stomach cardiac region mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach cardiac region mucous membrane" EXACT [OBOL:automatic] synonym: "stomach cardiac region organ mucosa" EXACT [OBOL:automatic] xref: FMA:17456 ! Mucosa of cardia of stomach intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001162 ! part_of cardia of stomach [Term] id: UBERON:0004997 name: mucosa of pyloric antrum def: "A mucosa that is part of a pyloric antrum [Automatically generated definition]." [OBOL:automatic] synonym: "antrum of stomach mucosa" EXACT [OBOL:automatic] synonym: "antrum of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "antrum of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "antrum of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of antrum of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of antrum of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of pyloric antrum" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "mucosa of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "mucous membrane of antrum of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of pyloric antrum" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "organ mucosa of antrum of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of pyloric antrum" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "pyloric antrum mucosa" EXACT [OBOL:automatic] synonym: "pyloric antrum mucosa of organ" EXACT [OBOL:automatic] synonym: "pyloric antrum mucous membrane" EXACT [OBOL:automatic] synonym: "pyloric antrum organ mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum mucous membrane" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum organ mucosa" EXACT [OBOL:automatic] xref: FMA:17055 ! Mucosa of pyloric antrum intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001165 ! part_of pyloric antrum [Term] id: UBERON:0004998 name: mucosa of pylorus def: "A mucosa that is part of a pylorus [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of pylorus" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach pyloric region" EXACT [OBOL:automatic] synonym: "mucosa of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "mucosa of stomach pyloric region" EXACT [OBOL:automatic] synonym: "mucous membrane of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of pylorus" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach pyloric region" EXACT [OBOL:automatic] synonym: "organ mucosa of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of pylorus" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach pyloric region" EXACT [OBOL:automatic] synonym: "pyloric part of stomach mucosa" EXACT [OBOL:automatic] synonym: "pyloric part of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "pyloric part of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "pyloric part of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "pylorus mucosa" EXACT [OBOL:automatic] synonym: "pylorus mucosa of organ" EXACT [OBOL:automatic] synonym: "pylorus mucous membrane" EXACT [OBOL:automatic] synonym: "pylorus organ mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric region mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric region mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach pyloric region mucous membrane" EXACT [OBOL:automatic] synonym: "stomach pyloric region organ mucosa" EXACT [OBOL:automatic] synonym: "antropyloric mucosa" RELATED [BTO:0002984] xref: FMA:17461 ! Mucosa of pylorus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001166 ! part_of pylorus xref: BTO:0002984 ! antropyloric mucosa xref: EMAPA:27199 ! mucosa of pyloric region of stomach of foregut xref: EMAPA:27499 ! mucosa of pyloric region of stomach of gut [Term] id: UBERON:0004999 name: mucosa of biliary tree def: "A mucosa that is part of a biliary tree [Automatically generated definition]." [OBOL:automatic] synonym: "biliary tract mucosa" EXACT [OBOL:automatic] synonym: "biliary tract mucosa of organ" EXACT [OBOL:automatic] synonym: "biliary tract mucous membrane" EXACT [OBOL:automatic] synonym: "biliary tract organ mucosa" EXACT [OBOL:automatic] synonym: "biliary tree mucosa" EXACT [OBOL:automatic] synonym: "biliary tree mucosa of organ" EXACT [OBOL:automatic] synonym: "biliary tree mucous membrane" EXACT [OBOL:automatic] synonym: "biliary tree organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of biliary tract" EXACT [OBOL:automatic] synonym: "mucosa of organ of biliary tract" EXACT [OBOL:automatic] synonym: "mucosa of organ of biliary tree" EXACT [OBOL:automatic] synonym: "mucous membrane of biliary tract" EXACT [OBOL:automatic] synonym: "mucous membrane of biliary tree" EXACT [OBOL:automatic] synonym: "organ mucosa of biliary tract" EXACT [OBOL:automatic] synonym: "organ mucosa of biliary tree" EXACT [OBOL:automatic] xref: FMA:14695 ! Mucosa of biliary tree intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001173 ! part_of biliary tree [Term] id: UBERON:0005000 name: mucosa of common bile duct def: "A mucosa that is part of a common bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "common bile duct mucosa" EXACT [OBOL:automatic] synonym: "common bile duct mucosa of organ" EXACT [OBOL:automatic] synonym: "common bile duct mucous membrane" EXACT [OBOL:automatic] synonym: "common bile duct organ mucosa" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) mucosa" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) mucosa of organ" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) mucous membrane" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "mucosa of organ of common bile duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "mucous membrane of common bile duct" EXACT [OBOL:automatic] synonym: "mucous membrane of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "organ mucosa of common bile duct" EXACT [OBOL:automatic] synonym: "organ mucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "common bile ductal mucosa" EXACT [FMA:14688] xref: FMA:14688 ! Mucosa of common bile duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001174 ! part_of common bile duct [Term] id: UBERON:0005001 name: mucosa of common hepatic duct def: "A mucosa that is part of a common hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "common hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "common hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "common hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "common hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of hepatic duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of common hepatic duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of common hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of common hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of hepatic duct" EXACT [OBOL:automatic] synonym: "common hepatic ductal mucosa" EXACT [FMA:14691] xref: FMA:14691 ! Mucosa of common hepatic duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001175 ! part_of common hepatic duct [Term] id: UBERON:0005002 name: mucosa of right hepatic duct def: "A mucosa that is part of a right hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of right hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of right hepatic duct" EXACT [OBOL:automatic] synonym: "right hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "right hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "right hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "right hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "right hepatic ductal mucosa" EXACT [FMA:14692] xref: FMA:14692 ! Mucosa of right hepatic duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001176 ! part_of right hepatic duct [Term] id: UBERON:0005003 name: mucosa of left hepatic duct def: "A mucosa that is part of a left hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "left hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "left hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "left hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "left hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of left hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of left hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of left hepatic duct" EXACT [OBOL:automatic] synonym: "left hepatic ductal mucosa" EXACT [FMA:14693] xref: FMA:14693 ! Mucosa of left hepatic duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001177 ! part_of left hepatic duct [Term] id: UBERON:0005004 name: mucosa of right ureter def: "A mucosa that is part of a right ureter [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of right ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of right ureter" EXACT [OBOL:automatic] synonym: "right ureter mucosa" EXACT [OBOL:automatic] synonym: "right ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "right ureter mucous membrane" EXACT [OBOL:automatic] synonym: "right ureter organ mucosa" EXACT [OBOL:automatic] synonym: "right ureteral mucosa" EXACT [FMA:17806] xref: FMA:17806 ! Mucosa of right ureter intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001222 ! part_of right ureter [Term] id: UBERON:0005005 name: mucosa of left ureter def: "A mucosa that is part of a left ureter [Automatically generated definition]." [OBOL:automatic] synonym: "left ureter mucosa" EXACT [OBOL:automatic] synonym: "left ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "left ureter mucous membrane" EXACT [OBOL:automatic] synonym: "left ureter organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of left ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of left ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of left ureter" EXACT [OBOL:automatic] synonym: "left ureteral mucosa" EXACT [FMA:17807] xref: FMA:17807 ! Mucosa of left ureter intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001223 ! part_of left ureter [Term] id: UBERON:0005006 name: mucosa of renal pelvis def: "A mucosa that is part of a renal pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "kidney pelvis mucosa" EXACT [OBOL:automatic] synonym: "kidney pelvis mucosa of organ" EXACT [OBOL:automatic] synonym: "kidney pelvis mucous membrane" EXACT [OBOL:automatic] synonym: "kidney pelvis organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucosa of organ of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucosa of organ of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucosa of organ of renal pelvis" EXACT [OBOL:automatic] synonym: "mucosa of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucous membrane of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of renal pelvis" EXACT [OBOL:automatic] synonym: "organ mucosa of kidney pelvis" EXACT [OBOL:automatic] synonym: "organ mucosa of pelvis of ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of renal pelvis" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucosa" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucous membrane" EXACT [OBOL:automatic] synonym: "pelvis of ureter organ mucosa" EXACT [OBOL:automatic] synonym: "renal pelvis mucosa" EXACT [OBOL:automatic] synonym: "renal pelvis mucosa of organ" EXACT [OBOL:automatic] synonym: "renal pelvis mucous membrane" EXACT [OBOL:automatic] synonym: "renal pelvis organ mucosa" EXACT [OBOL:automatic] synonym: "renal pelvic mucosa" EXACT [FMA:17931] xref: FMA:17931 ! Mucosa of renal pelvis intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001224 ! part_of renal pelvis synonym: "tunica mucosa pelvis renalis" EXACT LATIN [FMA:TA, FMA:17931] xref: SCTID:243482002 ! Entire mucous membrane of renal pelvis [Term] id: UBERON:0005007 name: mucosa of major calyx def: "A mucosa that is part of a major calyx [Automatically generated definition]." [OBOL:automatic] synonym: "major calix mucosa" EXACT [OBOL:automatic] synonym: "major calix mucosa of organ" EXACT [OBOL:automatic] synonym: "major calix mucous membrane" EXACT [OBOL:automatic] synonym: "major calix organ mucosa" EXACT [OBOL:automatic] synonym: "major calyx mucosa" EXACT [OBOL:automatic] synonym: "major calyx mucosa of organ" EXACT [OBOL:automatic] synonym: "major calyx mucous membrane" EXACT [OBOL:automatic] synonym: "major calyx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of major calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of major calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of major calyx" EXACT [OBOL:automatic] synonym: "mucous membrane of major calix" EXACT [OBOL:automatic] synonym: "mucous membrane of major calyx" EXACT [OBOL:automatic] synonym: "organ mucosa of major calix" EXACT [OBOL:automatic] synonym: "organ mucosa of major calyx" EXACT [OBOL:automatic] xref: FMA:17934 ! Mucosa of major calyx intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001226 ! part_of major calyx [Term] id: UBERON:0005008 name: mucosa of minor calyx def: "A mucosa that is part of a minor calyx [Automatically generated definition]." [OBOL:automatic] synonym: "minor calix mucosa" EXACT [OBOL:automatic] synonym: "minor calix mucosa of organ" EXACT [OBOL:automatic] synonym: "minor calix mucous membrane" EXACT [OBOL:automatic] synonym: "minor calix organ mucosa" EXACT [OBOL:automatic] synonym: "minor calyx mucosa" EXACT [OBOL:automatic] synonym: "minor calyx mucosa of organ" EXACT [OBOL:automatic] synonym: "minor calyx mucous membrane" EXACT [OBOL:automatic] synonym: "minor calyx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of minor calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of minor calix" EXACT [OBOL:automatic] synonym: "mucosa of organ of minor calyx" EXACT [OBOL:automatic] synonym: "mucous membrane of minor calix" EXACT [OBOL:automatic] synonym: "mucous membrane of minor calyx" EXACT [OBOL:automatic] synonym: "organ mucosa of minor calix" EXACT [OBOL:automatic] synonym: "organ mucosa of minor calyx" EXACT [OBOL:automatic] xref: FMA:17937 ! Mucosa of minor calyx intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001227 ! part_of minor calyx [Term] id: UBERON:0005009 name: mucosa of trigone of urinary bladder def: "A mucosa that is part of a trigone of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "Lieutaud ' s trigone mucosa" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone mucous membrane" EXACT [OBOL:automatic] synonym: "Lieutaud ' s trigone organ mucosa" EXACT [OBOL:automatic] synonym: "deep trigone mucosa" EXACT [OBOL:automatic] synonym: "deep trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "deep trigone mucous membrane" EXACT [OBOL:automatic] synonym: "deep trigone organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "mucosa of deep trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of deep trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of trigone of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "mucosa of organ of vesical trigone" EXACT [OBOL:automatic] synonym: "mucosa of trigone of bladder" EXACT [OBOL:automatic] synonym: "mucosa of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "mucosa of vesical trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of deep trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of trigone of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "mucous membrane of vesical trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of Lieutaud ' s trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of deep trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of trigone of bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of trigone of urinary bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of urinary bladder trigone" EXACT [OBOL:automatic] synonym: "organ mucosa of vesical trigone" EXACT [OBOL:automatic] synonym: "trigone of bladder mucosa" EXACT [OBOL:automatic] synonym: "trigone of bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "trigone of bladder mucous membrane" EXACT [OBOL:automatic] synonym: "trigone of bladder organ mucosa" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder mucosa" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder mucous membrane" EXACT [OBOL:automatic] synonym: "trigone of urinary bladder organ mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder trigone mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "urinary bladder trigone mucous membrane" EXACT [OBOL:automatic] synonym: "urinary bladder trigone organ mucosa" EXACT [OBOL:automatic] synonym: "vesical trigone mucosa" EXACT [OBOL:automatic] synonym: "vesical trigone mucosa of organ" EXACT [OBOL:automatic] synonym: "vesical trigone mucous membrane" EXACT [OBOL:automatic] synonym: "vesical trigone organ mucosa" EXACT [OBOL:automatic] xref: FMA:17847 ! Mucosa of trigone of urinary bladder intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001257 ! part_of trigone of urinary bladder [Term] id: UBERON:0005010 name: mucosa of neck of urinary bladder def: "A mucosa that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck mucosa" EXACT [OBOL:automatic] synonym: "bladder neck mucosa of organ" EXACT [OBOL:automatic] synonym: "bladder neck mucous membrane" EXACT [OBOL:automatic] synonym: "bladder neck organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of organ of neck of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of organ of vesical neck" EXACT [OBOL:automatic] synonym: "mucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of vesical neck" EXACT [OBOL:automatic] synonym: "mucous membrane of bladder neck" EXACT [OBOL:automatic] synonym: "mucous membrane of neck of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucous membrane of vesical neck" EXACT [OBOL:automatic] synonym: "neck of bladder mucosa" EXACT [OBOL:automatic] synonym: "neck of bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "neck of bladder mucous membrane" EXACT [OBOL:automatic] synonym: "neck of bladder organ mucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucous membrane" EXACT [OBOL:automatic] synonym: "neck of urinary bladder organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of bladder neck" EXACT [OBOL:automatic] synonym: "organ mucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "organ mucosa of vesical neck" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucosa of organ" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucous membrane" EXACT [OBOL:automatic] synonym: "vesical neck mucosa" EXACT [OBOL:automatic] synonym: "vesical neck mucosa of organ" EXACT [OBOL:automatic] synonym: "vesical neck mucous membrane" EXACT [OBOL:automatic] synonym: "vesical neck organ mucosa" EXACT [OBOL:automatic] xref: FMA:17846 ! Mucosa of neck of urinary bladder intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001258 ! part_of neck of urinary bladder [Term] id: UBERON:0005011 name: mucosa of right uterine tube def: "A mucosa that is part of a right uterine tube [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of right oviduct" EXACT [OBOL:automatic] synonym: "mucosa of organ of right uterine tube" EXACT [OBOL:automatic] synonym: "mucosa of right fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of right oviduct" EXACT [OBOL:automatic] synonym: "mucous membrane of right fallopian tube" EXACT [OBOL:automatic] synonym: "mucous membrane of right oviduct" EXACT [OBOL:automatic] synonym: "mucous membrane of right uterine tube" EXACT [OBOL:automatic] synonym: "organ mucosa of right fallopian tube" EXACT [OBOL:automatic] synonym: "organ mucosa of right oviduct" EXACT [OBOL:automatic] synonym: "organ mucosa of right uterine tube" EXACT [OBOL:automatic] synonym: "right fallopian tube mucosa" EXACT [OBOL:automatic] synonym: "right fallopian tube mucosa of organ" EXACT [OBOL:automatic] synonym: "right fallopian tube mucous membrane" EXACT [OBOL:automatic] synonym: "right fallopian tube organ mucosa" EXACT [OBOL:automatic] synonym: "right oviduct mucosa" EXACT [OBOL:automatic] synonym: "right oviduct mucosa of organ" EXACT [OBOL:automatic] synonym: "right oviduct mucous membrane" EXACT [OBOL:automatic] synonym: "right oviduct organ mucosa" EXACT [OBOL:automatic] synonym: "right uterine tube mucosa" EXACT [OBOL:automatic] synonym: "right uterine tube mucosa of organ" EXACT [OBOL:automatic] synonym: "right uterine tube mucous membrane" EXACT [OBOL:automatic] synonym: "right uterine tube organ mucosa" EXACT [OBOL:automatic] xref: FMA:18452 ! Mucosa of right uterine tube intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001302 ! part_of right uterine tube [Term] id: UBERON:0005012 name: mucosa of left uterine tube def: "A mucosa that is part of a left uterine tube [Automatically generated definition]." [OBOL:automatic] synonym: "left fallopian tube mucosa" EXACT [OBOL:automatic] synonym: "left fallopian tube mucosa of organ" EXACT [OBOL:automatic] synonym: "left fallopian tube mucous membrane" EXACT [OBOL:automatic] synonym: "left fallopian tube organ mucosa" EXACT [OBOL:automatic] synonym: "left oviduct mucosa" EXACT [OBOL:automatic] synonym: "left oviduct mucosa of organ" EXACT [OBOL:automatic] synonym: "left oviduct mucous membrane" EXACT [OBOL:automatic] synonym: "left oviduct organ mucosa" EXACT [OBOL:automatic] synonym: "left uterine tube mucosa" EXACT [OBOL:automatic] synonym: "left uterine tube mucosa of organ" EXACT [OBOL:automatic] synonym: "left uterine tube mucous membrane" EXACT [OBOL:automatic] synonym: "left uterine tube organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of left fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of left oviduct" EXACT [OBOL:automatic] synonym: "mucosa of organ of left fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of left oviduct" EXACT [OBOL:automatic] synonym: "mucosa of organ of left uterine tube" EXACT [OBOL:automatic] synonym: "mucous membrane of left fallopian tube" EXACT [OBOL:automatic] synonym: "mucous membrane of left oviduct" EXACT [OBOL:automatic] synonym: "mucous membrane of left uterine tube" EXACT [OBOL:automatic] synonym: "organ mucosa of left fallopian tube" EXACT [OBOL:automatic] synonym: "organ mucosa of left oviduct" EXACT [OBOL:automatic] synonym: "organ mucosa of left uterine tube" EXACT [OBOL:automatic] xref: FMA:18453 ! Mucosa of left uterine tube intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001303 ! part_of left uterine tube [Term] id: UBERON:0005013 name: mucosa of male urethra def: "A mucosa that is part of a male urethra [Automatically generated definition]." [OBOL:automatic] synonym: "male urethra mucosa" EXACT [OBOL:automatic] synonym: "male urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "male urethra mucous membrane" EXACT [OBOL:automatic] synonym: "male urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of male urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of male urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of male urethra" EXACT [OBOL:automatic] xref: FMA:239937 ! Mucosa of male urethra intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001333 ! part_of male urethra [Term] id: UBERON:0005014 name: mucosa of female urethra def: "A mucosa that is part of a female urethra [Automatically generated definition]." [OBOL:automatic] synonym: "female urethra mucosa" EXACT [OBOL:automatic] synonym: "female urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "female urethra mucous membrane" EXACT [OBOL:automatic] synonym: "female urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of female urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of female urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of female urethra" EXACT [OBOL:automatic] xref: FMA:239940 ! Mucosa of female urethra intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001334 ! part_of female urethra [Term] id: UBERON:0005015 name: mucosa of prostatic urethra def: "A mucosa that is part of a prostatic urethra [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of prostatic urethra" EXACT [OBOL:automatic] synonym: "mucosa of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of prostatic urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of prostatic part of urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of prostatic urethra" EXACT [OBOL:automatic] synonym: "prostatic part of urethra mucosa" EXACT [OBOL:automatic] synonym: "prostatic part of urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "prostatic part of urethra mucous membrane" EXACT [OBOL:automatic] synonym: "prostatic part of urethra organ mucosa" EXACT [OBOL:automatic] synonym: "prostatic urethra mucosa" EXACT [OBOL:automatic] synonym: "prostatic urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "prostatic urethra mucous membrane" EXACT [OBOL:automatic] synonym: "prostatic urethra organ mucosa" EXACT [OBOL:automatic] synonym: "prostatic urethral mucosa" EXACT [FMA:77079] xref: FMA:77079 ! Mucosa of prostatic urethra intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001335 ! part_of prostatic urethra synonym: "tunica mucosa urethrae prosticae" EXACT LATIN [FMA:TA, FMA:77079] [Term] id: UBERON:0005016 name: mucosa of intermediate urethra def: "A mucosa that is part of a membranous urethra [Automatically generated definition]." [OBOL:automatic] synonym: "intermediate part of urethra mucosa" EXACT [OBOL:automatic] synonym: "intermediate part of urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "intermediate part of urethra mucous membrane" EXACT [OBOL:automatic] synonym: "intermediate part of urethra organ mucosa" EXACT [OBOL:automatic] synonym: "intermediate urethra mucosa" EXACT [OBOL:automatic] synonym: "intermediate urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "intermediate urethra mucous membrane" EXACT [OBOL:automatic] synonym: "intermediate urethra organ mucosa" EXACT [OBOL:automatic] synonym: "membranous part of urethra mucosa" EXACT [OBOL:automatic] synonym: "membranous part of urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "membranous part of urethra mucous membrane" EXACT [OBOL:automatic] synonym: "membranous part of urethra organ mucosa" EXACT [OBOL:automatic] synonym: "membranous urethra mucosa" EXACT [OBOL:automatic] synonym: "membranous urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "membranous urethra mucous membrane" EXACT [OBOL:automatic] synonym: "membranous urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of membranous part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of membranous urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of intermediate urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of membranous part of urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of membranous urethra" EXACT [OBOL:automatic] synonym: "mucosa of organ of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "mucosa of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "mucous membrane of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of intermediate urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of membranous part of urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of membranous urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "organ mucosa of intermediate part of urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of intermediate urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of membranous part of urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of membranous urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of pars membranacea (urethrae)" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) mucosa" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) mucosa of organ" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) mucous membrane" EXACT [OBOL:automatic] synonym: "pars membranacea (urethrae) organ mucosa" EXACT [OBOL:automatic] synonym: "intermediate urethral mucosa" EXACT [FMA:77085] xref: FMA:77085 ! Mucosa of intermediate urethra intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001336 ! part_of membranous urethra xref: galen:MucousMembraneOfUrethra xref: SCTID:362229009 ! Entire mucous membrane of urethra [Term] id: UBERON:0005017 name: mucosa of lacrimal sac def: "A mucosa that is part of a lacrimal sac [Automatically generated definition]." [OBOL:automatic] synonym: "lacrimal sac mucosa" EXACT [OBOL:automatic] synonym: "lacrimal sac mucosa of organ" EXACT [OBOL:automatic] synonym: "lacrimal sac mucous membrane" EXACT [OBOL:automatic] synonym: "lacrimal sac organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of lacrimal sac" EXACT [OBOL:automatic] synonym: "mucous membrane of lacrimal sac" EXACT [OBOL:automatic] synonym: "organ mucosa of lacrimal sac" EXACT [OBOL:automatic] xref: FMA:72061 ! Mucosa of lacrimal sac intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001351 ! part_of lacrimal sac [Term] id: UBERON:0005018 name: mucosa of nasal septum def: "A mucosa that is part of a nasal septum [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of nasal septum" EXACT [OBOL:automatic] synonym: "mucous membrane of nasal septum" EXACT [OBOL:automatic] synonym: "nasal septum mucosa" EXACT [OBOL:automatic] synonym: "nasal septum mucosa of organ" EXACT [OBOL:automatic] synonym: "nasal septum mucous membrane" EXACT [OBOL:automatic] synonym: "nasal septum organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of nasal septum" EXACT [OBOL:automatic] xref: FMA:60113 ! Mucosa of nasal septum intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001706 ! part_of nasal septum [Term] id: UBERON:0005019 name: mucosa of palate def: "A mucosa that is part of a palate [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of oral roof" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral roof" EXACT [OBOL:automatic] synonym: "mucosa of organ of palate" EXACT [OBOL:automatic] synonym: "mucosa of organ of roof of mouth" EXACT [OBOL:automatic] synonym: "mucosa of roof of mouth" EXACT [OBOL:automatic] synonym: "mucous membrane of oral roof" EXACT [OBOL:automatic] synonym: "mucous membrane of palate" EXACT [OBOL:automatic] synonym: "mucous membrane of roof of mouth" EXACT [OBOL:automatic] synonym: "oral roof mucosa" EXACT [OBOL:automatic] synonym: "oral roof mucosa of organ" EXACT [OBOL:automatic] synonym: "oral roof mucous membrane" EXACT [OBOL:automatic] synonym: "oral roof organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of oral roof" EXACT [OBOL:automatic] synonym: "organ mucosa of palate" EXACT [OBOL:automatic] synonym: "organ mucosa of roof of mouth" EXACT [OBOL:automatic] synonym: "palate mucosa" EXACT [OBOL:automatic] synonym: "palate mucosa of organ" EXACT [OBOL:automatic] synonym: "palate mucous membrane" EXACT [OBOL:automatic] synonym: "palate organ mucosa" EXACT [OBOL:automatic] synonym: "roof of mouth mucosa" EXACT [OBOL:automatic] synonym: "roof of mouth mucosa of organ" EXACT [OBOL:automatic] synonym: "roof of mouth mucous membrane" EXACT [OBOL:automatic] synonym: "roof of mouth organ mucosa" EXACT [OBOL:automatic] xref: FMA:59765 ! Mucosa of palate intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001716 ! part_of secondary palate [Term] id: UBERON:0005020 name: mucosa of tongue def: "A mucosa that is part of a tongue [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of tongue" EXACT [OBOL:automatic] synonym: "mucous membrane of tongue" EXACT [OBOL:automatic] synonym: "organ mucosa of tongue" EXACT [OBOL:automatic] synonym: "tongue mucosa" EXACT [OBOL:automatic] synonym: "tongue mucosa of organ" EXACT [OBOL:automatic] synonym: "tongue mucous membrane" EXACT [OBOL:automatic] synonym: "tongue organ mucosa" EXACT [OBOL:automatic] synonym: "lingual mucosa" EXACT [FMA:54807] xref: FMA:54807 ! Mucosa of tongue xref: EFO:0002553 ! tongue mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001723 ! part_of tongue synonym: "tunica mucosa linguae" EXACT LATIN [FMA:TA, FMA:54807] xref: SCTID:362092002 ! Entire mucous membrane of tongue [Term] id: UBERON:0010052 name: mucosa of dorsum of tongue comment: Editor notes: check surface terms. Development notes: develops fungiform papillae by WNT induction at 11 weeks pc in human. Filiform papillae develop later. ISBN10:1607950324 synonym: "mucosa of dorsal surface of tongue" EXACT [] intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0009471 ! dorsum of tongue xref: FMA:74871 ! mucosa of dorsum of tongue xref: SCTID:245835003 ! Mucosa of dorsal surface of tongue def: "A mucosa that is part of a dorsum of tongue." [OBOL:automatic] [Term] id: UBERON:0005021 name: mucosa of sphenoidal sinus def: "A mucosa that is part of a sphenoidal sinus [Automatically generated definition]." [OBOL:automatic] comment: Editor note: decide whether cavities can be part of mucosae synonym: "mucosa of organ of sphenoid sinus" EXACT [OBOL:automatic] synonym: "mucosa of organ of sphenoidal sinus" EXACT [OBOL:automatic] synonym: "mucosa of sphenoid sinus" EXACT [OBOL:automatic] synonym: "mucous membrane of sphenoid sinus" EXACT [OBOL:automatic] synonym: "mucous membrane of sphenoidal sinus" EXACT [OBOL:automatic] synonym: "organ mucosa of sphenoid sinus" EXACT [OBOL:automatic] synonym: "organ mucosa of sphenoidal sinus" EXACT [OBOL:automatic] synonym: "sphenoid sinus mucosa" EXACT [OBOL:automatic] synonym: "sphenoid sinus mucosa of organ" EXACT [OBOL:automatic] synonym: "sphenoid sinus mucous membrane" EXACT [OBOL:automatic] synonym: "sphenoid sinus organ mucosa" EXACT [OBOL:automatic] synonym: "sphenoidal sinus mucosa" EXACT [OBOL:automatic] synonym: "sphenoidal sinus mucosa of organ" EXACT [OBOL:automatic] synonym: "sphenoidal sinus mucous membrane" EXACT [OBOL:automatic] synonym: "sphenoidal sinus organ mucosa" EXACT [OBOL:automatic] xref: FMA:59775 ! Mucosa of sphenoidal sinus intersection_of: UBERON:0000344 ! mucosa intersection_of: located_in UBERON:0001724 ! sphenoidal sinus relationship: part_of UBERON:0000033 ! head xref: SCTID:43774000 ! Entire mucous membrane of sphenoid sinus [Term] id: UBERON:0005022 name: mucosa of nasopharynx def: "A mucosa that is part of a nasopharynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of nasopharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of rhinopharynx" EXACT [OBOL:automatic] synonym: "mucosa of rhinopharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of nasopharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of rhinopharynx" EXACT [OBOL:automatic] synonym: "nasal part of pharynx mucosa" EXACT [OBOL:automatic] synonym: "nasal part of pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "nasal part of pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "nasal part of pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "nasopharynx mucosa" EXACT [OBOL:automatic] synonym: "nasopharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "nasopharynx mucous membrane" EXACT [OBOL:automatic] synonym: "nasopharynx organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of nasopharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of rhinopharynx" EXACT [OBOL:automatic] synonym: "rhinopharynx mucosa" EXACT [OBOL:automatic] synonym: "rhinopharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "rhinopharynx mucous membrane" EXACT [OBOL:automatic] synonym: "rhinopharynx organ mucosa" EXACT [OBOL:automatic] xref: FMA:54971 ! Mucosa of nasopharynx intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001728 ! part_of nasopharynx xref: SCTID:361938001 ! Entire mucous membrane of nasopharynx [Term] id: UBERON:0005023 name: mucosa of oropharynx def: "A mucosa that is part of a oropharynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of oral part of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral part of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of oropharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of oral part of pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of oropharynx" EXACT [OBOL:automatic] synonym: "oral part of pharynx mucosa" EXACT [OBOL:automatic] synonym: "oral part of pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "oral part of pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "oral part of pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of oral part of pharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of oropharynx" EXACT [OBOL:automatic] synonym: "oropharynx mucosa" EXACT [OBOL:automatic] synonym: "oropharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "oropharynx mucous membrane" EXACT [OBOL:automatic] synonym: "oropharynx organ mucosa" EXACT [OBOL:automatic] xref: FMA:54933 ! Mucosa of oropharynx intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001729 ! part_of oropharynx xref: SCTID:144632009 ! Entire mucous membrane of oropharynx [Term] id: UBERON:0005024 name: mucosa of soft palate def: "A mucosa that is part of a soft palate [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of soft palate" EXACT [OBOL:automatic] synonym: "mucous membrane of soft palate" EXACT [OBOL:automatic] synonym: "organ mucosa of soft palate" EXACT [OBOL:automatic] synonym: "soft palate mucosa" EXACT [OBOL:automatic] synonym: "soft palate mucosa of organ" EXACT [OBOL:automatic] synonym: "soft palate mucous membrane" EXACT [OBOL:automatic] synonym: "soft palate organ mucosa" EXACT [OBOL:automatic] xref: FMA:59784 ! Mucosa of soft palate intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001733 ! part_of soft palate xref: SCTID:245842003 ! Mucosa of soft palate [Term] id: UBERON:0005025 name: mucosa of uvula def: "A mucosa that is part of a uvula [Automatically generated definition]." [OBOL:automatic] synonym: "cerebellum lobule IX mucosa" EXACT [OBOL:automatic] synonym: "cerebellum lobule IX mucosa of organ" EXACT [OBOL:automatic] synonym: "cerebellum lobule IX mucous membrane" EXACT [OBOL:automatic] synonym: "cerebellum lobule IX organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of cerebellum lobule IX" EXACT [OBOL:automatic] synonym: "mucosa of organ of cerebellum lobule IX" EXACT [OBOL:automatic] synonym: "mucosa of organ of uvula" EXACT [OBOL:automatic] synonym: "mucosa of organ of uvula of palate" EXACT [OBOL:automatic] synonym: "mucosa of uvula of palate" EXACT [OBOL:automatic] synonym: "mucous membrane of cerebellum lobule IX" EXACT [OBOL:automatic] synonym: "mucous membrane of uvula" EXACT [OBOL:automatic] synonym: "mucous membrane of uvula of palate" EXACT [OBOL:automatic] synonym: "organ mucosa of cerebellum lobule IX" EXACT [OBOL:automatic] synonym: "organ mucosa of uvula" EXACT [OBOL:automatic] synonym: "organ mucosa of uvula of palate" EXACT [OBOL:automatic] synonym: "uvula mucosa" EXACT [OBOL:automatic] synonym: "uvula mucosa of organ" EXACT [OBOL:automatic] synonym: "uvula mucous membrane" EXACT [OBOL:automatic] synonym: "uvula of palate mucosa" EXACT [OBOL:automatic] synonym: "uvula of palate mucosa of organ" EXACT [OBOL:automatic] synonym: "uvula of palate mucous membrane" EXACT [OBOL:automatic] synonym: "uvula of palate organ mucosa" EXACT [OBOL:automatic] synonym: "uvula organ mucosa" EXACT [OBOL:automatic] xref: FMA:60030 ! Mucosa of uvula intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001734 ! part_of uvula [Term] id: UBERON:0005026 name: mucosa of middle ear def: "A mucosa that is part of a middle ear [Automatically generated definition]." [OBOL:automatic] synonym: "middle ear mucosa" EXACT [OBOL:automatic] synonym: "middle ear mucosa of organ" EXACT [OBOL:automatic] synonym: "middle ear mucous membrane" EXACT [OBOL:automatic] synonym: "middle ear organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of middle ear" EXACT [OBOL:automatic] synonym: "mucous membrane of middle ear" EXACT [OBOL:automatic] synonym: "organ mucosa of middle ear" EXACT [OBOL:automatic] synonym: "mucosa of tympanic cavity" EXACT [FMA:59663] xref: FMA:59663 ! Mucosa of middle ear intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001756 ! part_of middle ear synonym: "tunica mucosa cavitatis tympanicae" EXACT LATIN [FMA:TA, FMA:59663] [Term] id: UBERON:0005027 name: mucosa of frontal sinus def: "A mucosa that is part of a frontal sinus [Automatically generated definition]." [OBOL:automatic] synonym: "frontal sinus mucosa" EXACT [OBOL:automatic] synonym: "frontal sinus mucosa of organ" EXACT [OBOL:automatic] synonym: "frontal sinus mucous membrane" EXACT [OBOL:automatic] synonym: "frontal sinus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of frontal sinus" EXACT [OBOL:automatic] synonym: "mucous membrane of frontal sinus" EXACT [OBOL:automatic] synonym: "organ mucosa of frontal sinus" EXACT [OBOL:automatic] xref: FMA:59774 ! Mucosa of frontal sinus intersection_of: UBERON:0000344 ! mucosa intersection_of: located_in UBERON:0001760 ! part_of frontal sinus xref: SCTID:368909005 ! Entire mucous membrane of frontal sinus [Term] id: UBERON:0005028 name: mucosa of maxillary sinus def: "A mucosa that is part of a maxillary sinus [Automatically generated definition]." [OBOL:automatic] synonym: "antrum of highmore mucosa" EXACT [OBOL:automatic] synonym: "antrum of highmore mucosa of organ" EXACT [OBOL:automatic] synonym: "antrum of highmore mucous membrane" EXACT [OBOL:automatic] synonym: "antrum of highmore organ mucosa" EXACT [OBOL:automatic] synonym: "maxillary sinus mucosa" EXACT [OBOL:automatic] synonym: "maxillary sinus mucosa of organ" EXACT [OBOL:automatic] synonym: "maxillary sinus mucous membrane" EXACT [OBOL:automatic] synonym: "maxillary sinus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of antrum of highmore" EXACT [OBOL:automatic] synonym: "mucosa of organ of antrum of highmore" EXACT [OBOL:automatic] synonym: "mucosa of organ of maxillary sinus" EXACT [OBOL:automatic] synonym: "mucous membrane of antrum of highmore" EXACT [OBOL:automatic] synonym: "mucous membrane of maxillary sinus" EXACT [OBOL:automatic] synonym: "organ mucosa of antrum of highmore" EXACT [OBOL:automatic] synonym: "organ mucosa of maxillary sinus" EXACT [OBOL:automatic] xref: FMA:59773 ! Mucosa of maxillary sinus intersection_of: UBERON:0000344 ! mucosa intersection_of: located_in UBERON:0001764 ! part_of maxillary sinus xref: SCTID:368908002 ! Entire mucous membrane of maxillary sinus [Term] id: UBERON:0005029 name: mucosa of lacrimal canaliculus def: "A mucosa that is part of a lacrimal canaliculus [Automatically generated definition]." [OBOL:automatic] synonym: "lacrimal canaliculus mucosa" EXACT [OBOL:automatic] synonym: "lacrimal canaliculus mucosa of organ" EXACT [OBOL:automatic] synonym: "lacrimal canaliculus mucous membrane" EXACT [OBOL:automatic] synonym: "lacrimal canaliculus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of lacrimal canaliculus" EXACT [OBOL:automatic] synonym: "mucous membrane of lacrimal canaliculus" EXACT [OBOL:automatic] synonym: "organ mucosa of lacrimal canaliculus" EXACT [OBOL:automatic] synonym: "lacrimal canalicular mucosa" EXACT [FMA:85366] xref: FMA:85366 ! Mucosa of lacrimal canaliculus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001770 ! part_of lacrimal canaliculus [Term] id: UBERON:0005030 name: mucosa of paranasal sinus synonym: "paranasal sinus mucosa" EXACT [OBOL:automatic] xref: FMA:59772 ! Mucosa of paranasal sinus intersection_of: UBERON:0000344 ! mucosa intersection_of: adjacent_to UBERON:0001825 ! part_of paranasal sinus def: "A mucosa that adjacent_to a paranasal sinus." [OBOL:automatic] [Term] id: UBERON:0005031 name: mucosa of upper lip def: "A mucosa that is part of a upper lip [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of upper lip" EXACT [OBOL:automatic] synonym: "mucous membrane of upper lip" EXACT [OBOL:automatic] synonym: "organ mucosa of upper lip" EXACT [OBOL:automatic] synonym: "upper lip mucosa" EXACT [OBOL:automatic] synonym: "upper lip mucosa of organ" EXACT [OBOL:automatic] synonym: "upper lip mucous membrane" EXACT [OBOL:automatic] synonym: "upper lip organ mucosa" EXACT [OBOL:automatic] xref: FMA:59832 ! Mucosa of upper lip intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001834 ! part_of upper lip xref: ncithesaurus:Mucosa_of_the_Upper_Lip ! Mucosa of the Upper Lip xref: SCTID:362088009 ! Entire mucous membrane of upper lip xref: UMLS:C0226933 [Term] id: UBERON:0005032 name: mucosa of lower lip def: "A mucosa that is part of a lower lip [Automatically generated definition]." [OBOL:automatic] synonym: "lower lip mucosa" EXACT [OBOL:automatic] synonym: "lower lip mucosa of organ" EXACT [OBOL:automatic] synonym: "lower lip mucous membrane" EXACT [OBOL:automatic] synonym: "lower lip organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of lower lip" EXACT [OBOL:automatic] synonym: "mucous membrane of lower lip" EXACT [OBOL:automatic] synonym: "organ mucosa of lower lip" EXACT [OBOL:automatic] xref: FMA:59833 ! Mucosa of lower lip intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001835 ! part_of lower lip xref: ncithesaurus:Mucosa_of_the_Lower_Lip ! Mucosa of the Lower Lip xref: SCTID:362089001 ! Entire mucous membrane of lower lip xref: UMLS:C0226939 [Term] id: UBERON:0005033 name: mucosa of gallbladder def: "A mucosa that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "gall bladder mucosa" EXACT [OBOL:automatic] synonym: "gall bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "gall bladder mucous membrane" EXACT [OBOL:automatic] synonym: "gall bladder organ mucosa" EXACT [OBOL:automatic] synonym: "gallbladder mucosa" EXACT [OBOL:automatic] synonym: "gallbladder mucosa of organ" EXACT [OBOL:automatic] synonym: "gallbladder mucous membrane" EXACT [OBOL:automatic] synonym: "gallbladder organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of gall bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of gall bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of gallbladder" EXACT [OBOL:automatic] synonym: "mucous membrane of gall bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of gallbladder" EXACT [OBOL:automatic] synonym: "organ mucosa of gall bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of gallbladder" EXACT [OBOL:automatic] synonym: "tunica mucosa (vesica biliaris)" EXACT [FMA:14662] xref: FMA:14662 ! Mucosa of gallbladder intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002110 ! part_of gallbladder synonym: "tunica mucosa vesicae biliaris" EXACT LATIN [FMA:TA, FMA:14662] xref: SCTID:362196002 ! Entire mucosa of gallbladder [Term] id: UBERON:0005034 name: mucosa of right main bronchus def: "A mucosa that is part of a right main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of right main bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of right principal bronchus" EXACT [OBOL:automatic] synonym: "mucosa of right bronchus" EXACT [OBOL:automatic] synonym: "mucosa of right principal bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of right bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of right main bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of right principal bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of right bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of right main bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of right principal bronchus" EXACT [OBOL:automatic] synonym: "right bronchus mucosa" EXACT [OBOL:automatic] synonym: "right bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "right bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "right bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "right main bronchus mucosa" EXACT [OBOL:automatic] synonym: "right main bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "right main bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "right main bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "right principal bronchus mucosa" EXACT [OBOL:automatic] synonym: "right principal bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "right principal bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "right principal bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "right main bronchial mucosa" EXACT [FMA:13137] xref: FMA:13137 ! Mucosa of right main bronchus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002177 ! part_of right main bronchus [Term] id: UBERON:0005035 name: mucosa of left main bronchus def: "A mucosa that is part of a left main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "left bronchus mucosa" EXACT [OBOL:automatic] synonym: "left bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "left bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "left bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "left main bronchus mucosa" EXACT [OBOL:automatic] synonym: "left main bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "left main bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "left main bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "left principal bronchus mucosa" EXACT [OBOL:automatic] synonym: "left principal bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "left principal bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "left principal bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of left bronchus" EXACT [OBOL:automatic] synonym: "mucosa of left principal bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of left bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of left main bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of left principal bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of left bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of left main bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of left principal bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of left bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of left main bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of left principal bronchus" EXACT [OBOL:automatic] synonym: "left main bronchial mucosa" EXACT [FMA:13138] xref: FMA:13138 ! Mucosa of left main bronchus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002178 ! part_of left main bronchus [Term] id: UBERON:0005036 name: mucosa of main bronchus def: "A mucosa that is part of a main bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchus principalis mucosa" EXACT [OBOL:automatic] synonym: "bronchus principalis mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchus principalis mucous membrane" EXACT [OBOL:automatic] synonym: "bronchus principalis organ mucosa" EXACT [OBOL:automatic] synonym: "main bronchus mucosa" EXACT [OBOL:automatic] synonym: "main bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "main bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "main bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bronchus principalis" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchus principalis" EXACT [OBOL:automatic] synonym: "mucosa of organ of main bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of primary bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of principal bronchus" EXACT [OBOL:automatic] synonym: "mucosa of primary bronchus" EXACT [OBOL:automatic] synonym: "mucosa of principal bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchus principalis" EXACT [OBOL:automatic] synonym: "mucous membrane of main bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of primary bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of principal bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchus principalis" EXACT [OBOL:automatic] synonym: "organ mucosa of main bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of primary bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of principal bronchus" EXACT [OBOL:automatic] synonym: "primary bronchus mucosa" EXACT [OBOL:automatic] synonym: "primary bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "primary bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "primary bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "principal bronchus mucosa" EXACT [OBOL:automatic] synonym: "principal bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "principal bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "principal bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "main bronchial mucosa" EXACT [FMA:13115] xref: FMA:13115 ! Mucosa of main bronchus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002182 ! part_of main bronchus [Term] id: UBERON:0005037 name: mucosa of lobar bronchus def: "A mucosa that is part of a lobar bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "lobar bronchus mucosa" EXACT [OBOL:automatic] synonym: "lobar bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "lobar bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "lobar bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of lobar bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of secondary bronchus" EXACT [OBOL:automatic] synonym: "mucosa of secondary bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of lobar bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of secondary bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of lobar bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of secondary bronchus" EXACT [OBOL:automatic] synonym: "secondary bronchus mucosa" EXACT [OBOL:automatic] synonym: "secondary bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "secondary bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "secondary bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "lobar bronchial mucosa" EXACT [FMA:62668] xref: FMA:62668 ! Mucosa of lobar bronchus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002183 ! part_of lobar bronchus [Term] id: UBERON:0005038 name: mucosa of segmental bronchus def: "A mucosa that is part of a segmental bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of segmental bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of tertiary bronchus" EXACT [OBOL:automatic] synonym: "mucosa of tertiary bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of segmental bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of tertiary bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of segmental bronchus" EXACT [OBOL:automatic] synonym: "organ mucosa of tertiary bronchus" EXACT [OBOL:automatic] synonym: "segmental bronchus mucosa" EXACT [OBOL:automatic] synonym: "segmental bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "segmental bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "segmental bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "tertiary bronchus mucosa" EXACT [OBOL:automatic] synonym: "tertiary bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "tertiary bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "tertiary bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "segmental bronchial mucosa" EXACT [FMA:62666] xref: FMA:62666 ! Mucosa of segmental bronchus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002184 ! part_of segmental bronchus [Term] id: UBERON:0005039 name: mucosa of bronchiole def: "A mucosa that is part of a bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole mucosa" EXACT [OBOL:automatic] synonym: "bronchiole mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchiole mucous membrane" EXACT [OBOL:automatic] synonym: "bronchiole organ mucosa" EXACT [OBOL:automatic] synonym: "lobular bronchiole mucosa" EXACT [OBOL:automatic] synonym: "lobular bronchiole mucosa of organ" EXACT [OBOL:automatic] synonym: "lobular bronchiole mucous membrane" EXACT [OBOL:automatic] synonym: "lobular bronchiole organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of lobular bronchiole" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchiole" EXACT [OBOL:automatic] synonym: "mucosa of organ of lobular bronchiole" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchiole" EXACT [OBOL:automatic] synonym: "mucous membrane of lobular bronchiole" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchiole" EXACT [OBOL:automatic] synonym: "organ mucosa of lobular bronchiole" EXACT [OBOL:automatic] xref: FMA:263230 ! Mucosa of lobular bronchiole xref: FMA:62774 ! Mucosa of bronchiole intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002186 ! part_of bronchiole xref: SCTID:10887006 ! Mucous membrane of bronchiole [Term] id: UBERON:0005040 name: mucosa of terminal bronchiole def: "A mucosa that is part of a terminal bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus terminalis mucosa" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis mucous membrane" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "mucosa of organ of terminal bronchiole" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "mucous membrane of terminal bronchiole" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "organ mucosa of terminal bronchiole" EXACT [OBOL:automatic] synonym: "terminal bronchiole mucosa" EXACT [OBOL:automatic] synonym: "terminal bronchiole mucosa of organ" EXACT [OBOL:automatic] synonym: "terminal bronchiole mucous membrane" EXACT [OBOL:automatic] synonym: "terminal bronchiole organ mucosa" EXACT [OBOL:automatic] xref: FMA:263232 ! Mucosa of terminal bronchiole intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002187 ! part_of terminal bronchiole [Term] id: UBERON:0005041 name: mucosa of respiratory bronchiole def: "A mucosa that is part of a respiratory bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus respiratorius mucosa" EXACT [OBOL:automatic] synonym: "bronchiolus respiratorius mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchiolus respiratorius mucous membrane" EXACT [OBOL:automatic] synonym: "bronchiolus respiratorius organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bronchiolus respiratorius" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchiolus respiratorius" EXACT [OBOL:automatic] synonym: "mucosa of organ of respiratory bronchiole" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchiolus respiratorius" EXACT [OBOL:automatic] synonym: "mucous membrane of respiratory bronchiole" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchiolus respiratorius" EXACT [OBOL:automatic] synonym: "organ mucosa of respiratory bronchiole" EXACT [OBOL:automatic] synonym: "respiratory bronchiole mucosa" EXACT [OBOL:automatic] synonym: "respiratory bronchiole mucosa of organ" EXACT [OBOL:automatic] synonym: "respiratory bronchiole mucous membrane" EXACT [OBOL:automatic] synonym: "respiratory bronchiole organ mucosa" EXACT [OBOL:automatic] xref: FMA:263238 ! Mucosa of respiratory bronchiole intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002188 ! part_of respiratory bronchiole [Term] id: UBERON:0005043 name: mucosa of nasolacrimal duct def: "A mucosa that is part of a nasolacrimal duct [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of nasolacrimal duct" EXACT [OBOL:automatic] synonym: "mucous membrane of nasolacrimal duct" EXACT [OBOL:automatic] synonym: "nasolacrimal duct mucosa" EXACT [OBOL:automatic] synonym: "nasolacrimal duct mucosa of organ" EXACT [OBOL:automatic] synonym: "nasolacrimal duct mucous membrane" EXACT [OBOL:automatic] synonym: "nasolacrimal duct organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of nasolacrimal duct" EXACT [OBOL:automatic] synonym: "nasolacrimal ductal mucosa" EXACT [FMA:59664] xref: FMA:59664 ! Mucosa of nasolacrimal duct intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002392 ! part_of nasolacrimal duct [Term] id: UBERON:0005044 name: mucosa of pharyngotympanic tube def: "A mucosa that is part of a pharyngotympanic tube [Automatically generated definition]." [OBOL:automatic] synonym: "auditory tube mucosa" EXACT [OBOL:automatic] synonym: "auditory tube mucosa of organ" EXACT [OBOL:automatic] synonym: "auditory tube mucous membrane" EXACT [OBOL:automatic] synonym: "auditory tube organ mucosa" EXACT [OBOL:automatic] synonym: "internal auditory tube mucosa" EXACT [OBOL:automatic] synonym: "internal auditory tube mucosa of organ" EXACT [OBOL:automatic] synonym: "internal auditory tube mucous membrane" EXACT [OBOL:automatic] synonym: "internal auditory tube organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of auditory tube" EXACT [OBOL:automatic] synonym: "mucosa of internal auditory tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of auditory tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of internal auditory tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of pharyngotympanic tube" EXACT [OBOL:automatic] synonym: "mucous membrane of auditory tube" EXACT [OBOL:automatic] synonym: "mucous membrane of internal auditory tube" EXACT [OBOL:automatic] synonym: "mucous membrane of pharyngotympanic tube" EXACT [OBOL:automatic] synonym: "organ mucosa of auditory tube" EXACT [OBOL:automatic] synonym: "organ mucosa of internal auditory tube" EXACT [OBOL:automatic] synonym: "organ mucosa of pharyngotympanic tube" EXACT [OBOL:automatic] synonym: "pharyngotympanic tube mucosa" EXACT [OBOL:automatic] synonym: "pharyngotympanic tube mucosa of organ" EXACT [OBOL:automatic] synonym: "pharyngotympanic tube mucous membrane" EXACT [OBOL:automatic] synonym: "pharyngotympanic tube organ mucosa" EXACT [OBOL:automatic] synonym: "mucuous membrane of eustachian tube" EXACT [FMA:60109] synonym: "mucuous membrane of pharyngotympanic tube" EXACT [FMA:60109] synonym: "tunica mucosa (tuba auditiva)" EXACT [FMA:60109] synonym: "tunica mucosa (tuba auditoria)" EXACT [FMA:60109] xref: FMA:60109 ! Mucosa of pharyngotympanic tube intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002393 ! part_of pharyngotympanic tube [Term] id: UBERON:0005045 name: mucosa of ethmoidal sinus def: "A mucosa that is part of a ethmoid sinus [Automatically generated definition]." [OBOL:automatic] synonym: "ethmoid sinus mucosa" EXACT [OBOL:automatic] synonym: "ethmoid sinus mucosa of organ" EXACT [OBOL:automatic] synonym: "ethmoid sinus mucous membrane" EXACT [OBOL:automatic] synonym: "ethmoid sinus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of ethmoid sinus" EXACT [OBOL:automatic] synonym: "mucosa of organ of ethmoid sinus" EXACT [OBOL:automatic] synonym: "mucous membrane of ethmoid sinus" EXACT [OBOL:automatic] synonym: "organ mucosa of ethmoid sinus" EXACT [OBOL:automatic] synonym: "ethmoidal sinus mucosa" EXACT [FMA:59776] xref: FMA:59776 ! Mucosa of ethmoidal sinus intersection_of: UBERON:0000344 ! mucosa intersection_of: located_in UBERON:0002453 ! part_of ethmoid sinus xref: SCTID:65501003 ! Entire mucous membrane of ethmoid sinus [Term] id: UBERON:0005047 name: mucosa of vocal fold def: "A mucosa that is part of a vocal cord [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of true vocal cord" EXACT [OBOL:automatic] synonym: "mucosa of organ of vocal cord" EXACT [OBOL:automatic] synonym: "mucosa of true vocal cord" EXACT [OBOL:automatic] synonym: "mucosa of vocal cord" EXACT [OBOL:automatic] synonym: "mucous membrane of true vocal cord" EXACT [OBOL:automatic] synonym: "mucous membrane of vocal cord" EXACT [OBOL:automatic] synonym: "organ mucosa of true vocal cord" EXACT [OBOL:automatic] synonym: "organ mucosa of vocal cord" EXACT [OBOL:automatic] synonym: "true vocal cord mucosa" EXACT [OBOL:automatic] synonym: "true vocal cord mucosa of organ" EXACT [OBOL:automatic] synonym: "true vocal cord mucous membrane" EXACT [OBOL:automatic] synonym: "true vocal cord organ mucosa" EXACT [OBOL:automatic] synonym: "vocal cord mucosa" EXACT [OBOL:automatic] synonym: "vocal cord mucosa of organ" EXACT [OBOL:automatic] synonym: "vocal cord mucous membrane" EXACT [OBOL:automatic] synonym: "vocal cord organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of glottis" EXACT [FMA:64017] synonym: "vocal fold mucosa" EXACT [FMA:64017] xref: FMA:64017 ! Mucosa of vocal fold intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0003706 ! part_of vocal cord [Term] id: UBERON:0005048 name: mucosa of uterine tube def: "A mucosa that is part of a fallopian tube [Automatically generated definition]." [OBOL:automatic] synonym: "fallopian tube mucosa" EXACT [OBOL:automatic] synonym: "fallopian tube mucosa of organ" EXACT [OBOL:automatic] synonym: "fallopian tube mucous membrane" EXACT [OBOL:automatic] synonym: "fallopian tube organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of uterine tube" EXACT [OBOL:automatic] synonym: "mucous membrane of fallopian tube" EXACT [OBOL:automatic] synonym: "mucous membrane of uterine tube" EXACT [OBOL:automatic] synonym: "organ mucosa of fallopian tube" EXACT [OBOL:automatic] synonym: "organ mucosa of uterine tube" EXACT [OBOL:automatic] synonym: "uterine tube mucosa" EXACT [OBOL:automatic] synonym: "uterine tube mucosa of organ" EXACT [OBOL:automatic] synonym: "uterine tube mucous membrane" EXACT [OBOL:automatic] synonym: "uterine tube organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of oviduct" EXACT [FMA:18319] synonym: "uterine tubal mucosa" EXACT [FMA:18319] xref: FMA:18319 ! Mucosa of uterine tube intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0003889 ! part_of fallopian tube synonym: "tunica mucosa tubae uterinae" EXACT LATIN [FMA:TA, FMA:18319] [Term] id: UBERON:0005049 name: mucosa of infundibulum of uterine tube def: "A mucosa that is part of a uterine tube infundibulum [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "mucosa of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "mucous membrane of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "organ mucosa of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum mucosa" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum mucosa of organ" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum mucous membrane" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of infundibulum of fallopian tube" EXACT [FMA:18357] synonym: "mucosa of infundibulum of oviduct" EXACT [FMA:18357] xref: FMA:18357 ! Mucosa of infundibulum of uterine tube intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0003984 ! part_of uterine tube infundibulum [Term] id: UBERON:0005057 name: immune organ def: "An organ that is part of a immune system [Automatically generated definition]." [OBOL:automatic] intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002405 ! immune system subset: organ_slim [Term] id: UBERON:0005058 name: hemolymphoid system gland def: "A gland that is part of a hemolymphoid system [Automatically generated definition]." [OBOL:automatic] synonym: "hemopoietic or lymphoid organ" BROAD [GO:0048534] synonym: "hemopoietic or lymphoid gland" EXACT [GOC:cjm] xref: MA:0002962 ! hemolymphoid system gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002193 ! hemolymphoid system subset: organ_slim [Term] id: UBERON:0005063 name: left ventricular compact myocardium def: "." [GO:0003224] intersection_of: UBERON:0004127 ! compact layer of ventricle intersection_of: part_of UBERON:0002084 ! left ventricle relationship: part_of UBERON:0003382 {source="GO"} ! cardiac muscle of left ventricle relationship: part_of UBERON:0006566 {is_inferred="true", source="reference_0000032"} ! left ventricle myocardium [Term] id: UBERON:0005064 name: left ventricular trabecular myocardium def: "." [GO:0003225] intersection_of: UBERON:0004126 ! trabecular layer of ventricle intersection_of: part_of UBERON:0002084 ! left ventricle relationship: part_of UBERON:0003382 {source="GO"} ! cardiac muscle of left ventricle [Term] id: UBERON:0005065 name: right ventricular compact myocardium def: "." [GO:0003226] intersection_of: UBERON:0004127 ! compact layer of ventricle intersection_of: part_of UBERON:0002080 ! right ventricle relationship: part_of UBERON:0003381 {source="GO"} ! cardiac muscle of right ventricle relationship: part_of UBERON:0006567 {is_inferred="true", source="reference_0000032"} ! right ventricle myocardium [Term] id: UBERON:0005066 name: right ventricular trabecular myocardium def: "." [GO:0003227] intersection_of: UBERON:0004126 ! trabecular layer of ventricle intersection_of: part_of UBERON:0002080 ! right ventricle relationship: part_of UBERON:0003381 {source="GO"} ! cardiac muscle of right ventricle [Term] id: UBERON:0005067 name: amphid sensory organ def: "Amphid sensory organs are the sensory organs of nematodes[GO]." [GO:0003386] synonym: "amphid sensillum" EXACT [] xref: WBbt:0005391 ! amphid sensillum is_a: UBERON:0000020 ! sense organ relationship: only_in_taxon NCBITaxon:6231 ! Nematoda subset: organ_slim [Term] id: UBERON:0005069 name: neural fold hinge point def: "The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube[GO]." [GO:0021504] is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0001049 ! neural tube [Term] id: UBERON:0005077 ! neuropore name: neuropore def: "Joined neural folds at either end of the neural tube.[GO]." [GO:0021995] is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0001049 ! neural tube xref: SCTID:360408007 ! Neuropore [Term] id: UBERON:0005070 name: anterior neuropore def: "The anterior neuropore appears before the process of neural tube closure is complete[GO]." [GO:0021506] comment: GO def of anterior neuropore closure is: The joining together of the neural folds of the rostral opening of the neural tube synonym: "rostral neuropore" EXACT [EMAPA:16523] synonym: "cranial neuropore" EXACT [UBERON:cjm] synonym: "cephalic neuropore" EXACT [SCTID:361478000] xref: EMAPA:16523 ! rostral neuropore xref: VHOG:0000768 ! rostral neuropore xref: RETIRED_EHDAA2:0001768 ! rostral neuropore is_a: UBERON:0005077 ! neuropore xref: SCTID:361478000 ! Cephalic neuropore xref: EHDAA2:0004203 ! rostral neuropore property_value: external_definition "Anterior site of neural tube closure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.378, see_Kardong_KV][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000768", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005071 name: posterior neuropore def: "The posterior neuropore appears before the process of neural tube closure is complete[GO]." [GO:0021507] synonym: "caudal neuropore" EXACT [EMAPA:16526] xref: EMAPA:16526 ! caudal neuropore xref: VHOG:0000769 ! caudal neuropore xref: RETIRED_EHDAA2:0000223 ! caudal neuropore xref: EHDAA:900 ! caudal neuropore is_a: UBERON:0005077 ! neuropore xref: SCTID:361479008 ! Caudal neuropore xref: EHDAA2:0000676 ! caudal neuropore property_value: external_definition "Posterior site of neural tube closure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.378, see_Kardong_KV][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000769", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005078 name: lamina terminalis def: "." [GO:0021996] xref: FMA:61975 ! Lamina terminalis xref: EMAPA:16649 ! lamina terminalis of diencephalon of future forebrain xref: EMAPA:16904 ! lamina terminalis of diencephalon of forebrain xref: EHDAA2:0000903 ! lamina terminalis xref: AAO:0000881 ! lamina terminalis xref: BM:LT ! lamina terminalis is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0005070 ! anterior neuropore xref: SCTID:361483008 ! Lamina terminalis property_value: external_definition "In those cases in which the interilial region is broadly expanded and the pubis is extremely reduced, the anterior margin of the ischium forms an expanded area.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000881", date_retrieved="2012-06-20", source="AAO:LAP"} xref: VHOG:0001547 ! lamina terminalis [Term] id: UBERON:0005073 name: preganglionic parasympathetic nervous system is_a: UBERON:0000011 ! parasympathetic nervous system [Term] id: UBERON:0005074 name: postganglionic parasympathetic nervous system is_a: UBERON:0000011 ! parasympathetic nervous system relationship: develops_from UBERON:0005073 ! preganglionic parasympathetic nervous system [Term] id: UBERON:0005075 name: forebrain-midbrain boundary synonym: "forebrain midbrain boundary" EXACT [ZFA:0001367] xref: ZFA:0001367 ! forebrain midbrain boundary intersection_of: UBERON:0000015 ! anatomical boundary intersection_of: adjacent_to UBERON:0001890 ! forebrain intersection_of: adjacent_to UBERON:0001891 ! midbrain relationship: develops_from UBERON:0007288 {evidence="definitional"} ! presumptive forebrain midbrain boundary xref: TAO:0001367 ! forebrain midbrain boundary property_value: external_definition "The boundary between the diencephalon and the mesencephalon.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001367", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from forebrain midbrain boundary neural tube (TAO:0007040)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001367", date_retrieved="2012-08-14"} def: "An anatomical boundary that adjacent_to a forebrain and adjacent_to a midbrain." [OBOL:automatic] [Term] id: UBERON:0005076 name: hindbrain-spinal cord boundary intersection_of: UBERON:0000015 ! anatomical boundary intersection_of: adjacent_to UBERON:0002028 ! hindbrain intersection_of: adjacent_to UBERON:0002240 ! spinal cord def: "An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord." [OBOL:automatic] [Term] id: UBERON:0007379 name: egg def: "The hard-shelled reproductive body produced by a bird and especially by the common domestic chicken; also: its contents used as food." [BTO:0000369, Wikipedia:Egg_(biology)] xref: BTO:0000369 ! egg is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000474 ! female reproductive system xref: CALOHA:TS-2191 ! Ovum [Term] id: UBERON:0005079 name: eggshell def: "a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration[GO]." [GO:0030703, Wikipedia:Eggshell] synonym: "egg shell" EXACT [BTO:0001716] xref: BTO:0001716 ! eggshell xref: WBbt:0005843 ! eggshell xref: MESH:A13.316 ! egg shell is_a: UBERON:0000476 ! acellular anatomical structure relationship: surrounds UBERON:0007379 ! egg [Term] id: UBERON:0005307 name: chorion-containing eggshell def: "An eggshell that contains chorion. An example of this is found in Drosophila melanogaster." [GO:0007304] is_a: UBERON:0005079 ! eggshell relationship: has_part UBERON:0000920 ! egg chorion [Term] id: UBERON:0007378 name: egg yolk def: "The yellow spheroidal mass of stored food that forms the inner portion of the egg of a bird or reptile and is surrounded by the white." [BTO:0000371, Wikipedia:Yolk] synonym: "yolk" RELATED [BTO:0000371] xref: BTO:0000371 ! egg yolk xref: MESH:A16.631.325 ! egg yolk is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0007379 ! egg xref: ncithesaurus:Egg_Yolk ! Egg Yolk xref: AAO:0010579 ! yolk property_value: external_definition "Extraembryonic structure that serves as a nutrient store for the embryo during development.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010579", date_retrieved="2012-06-20", source="AAO:EJS"} xref: VHOG:0001742 ! yolk property_value: homology_notes "The majority of animals develop from a spherical egg with a single axis, the animal-vegetal (an-veg) axis. The animal half of the egg usually contains the nucleus of the oocyte, while the vegetal half of the egg is the preferred site for the storage of yolk. Eggs with an-veg polarity are considered ancestral for the vertebrates. Frogs, for example, have eggs with vegetally concentrated yolk and the nucleus located in the animal cytoplasm.[well established][VHOG]" xsd:string {external_class="VHOG:0001742", ontology="VHOG", source="DOI:10.1016/S0925-4773(98)00226-3 Arendt D\, Nubler-Jung K\, Rearranging gastrulation in the name of yolk: evolution of gastrulation in yolk-rich amniote eggs. Mechanism of Development (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005082 name: tube lumen def: "A hole in a tube[GO]." [GO:0060609] xref: RETIRED_EHDAA2:0003078 ! lumen of tube xref: AEO:0000078 ! lumen of tube intersection_of: UBERON:0000464 ! anatomical space intersection_of: surrounded_by UBERON:0000025 ! tube xref: EHDAA2:0004618 ! lumen of tube [Term] id: UBERON:0005083 name: nipple sheath def: "a circular ingrowth of the epidermis around the region of the mammary sprout[GO]." [GO:0060659] is_a: UBERON:0001003 ! epidermis relationship: part_of UBERON:0002030 ! nipple [Term] id: UBERON:0009200 name: limb epidermis def: "The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium." [GOC:dph, GOC:sdb_2009, GOC:tb] intersection_of: UBERON:0001003 ! epidermis intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0005085 name: ectodermal placode def: "An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO]" [GO:0060788] comment: Homology: With the exception of the adenohypophysis, homologues of the nonneurogenic placodes (e.g. placodes giving rise to the teeth, hair follicles and lens), appear to be lacking in invertebrate chordates. Editor notes: consder adding placodal ectoderm as a distinct class? Also place placodal ectoderm as develops_from ectoderm // AO notes: in GO, covers optic, otic, olfactory, mammary, hair, tooth, sebaceous intersection_of: UBERON:0001048 ! primordium intersection_of: part_of UBERON:0000924 ! ectoderm [Term] id: UBERON:0002546 name: cranial placode def: "Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic." [http://www.ncbi.nlm.nih.gov/books/NBK53175/, UBERON:cjm, https://github.com/seger/aao/issues/4, https://sourceforge.net/tracker/?func=detail&aid=3561940&group_id=76834&atid=1127722] comment: Editor note: to avoid confusion, we include neurogenic placode as a subclass. Do not merge. Terminological notes: The term placode or placodes also applies to developing organs such as teeth, mammary glands, hair follicles, feathers and scales. We include a separate parent class for this. Taxon notes: Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons[PMID:11523831]. synonym: "placode" BROAD [Wikipedia:Placode] xref: MAT:0000369 ! cranial placode xref: MIAA:0000369 ! cranial placode xref: XAO:0000305 ! cranial placode xref: AAO:0010466 ! cranial placode is_a: UBERON:0005085 {source="cjm"} ! ectodermal placode relationship: part_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:7711 {source="PMID:11523831"} ! Chordata xref: EFO:0001650 ! placode [Term] id: UBERON:0011814 ! non-neurogenic ectodermal placode name: non-neurogenic ectodermal placode is_a: UBERON:0005085 {source="cjm"} ! ectodermal placode disjoint_from: UBERON:0009955 ! neurogenic placode [Term] id: UBERON:0009955 name: neurogenic placode def: "Cranial placode with neurogenic potential[cjm]. Neurogenic placodes are transient ectodermal thickenings that form at the border of the neural plate and epidermis and give rise to sensory neurons of the cranial ganglia[ZFA]. The neurogenic placodes give rise to parts of various nerves and ganglia, the olfactory organ, parietal eye, parts of the inner ear, and the lateral line. There are 2 major series of neurogenic placodes, the dorsolateral and ventrolateral or epibranchial[PMID]" [ZFA:0001309, Wikipedia:Neurogenic_placodes, PMID:11523831] comment: Includes: trigeminal, otic, lateral line and epibranchial placodes. Taxon notes: While some sensory placodes (otic and olfactory) may have homologues in basal chordates (Wada et al., 1998), the so-called neurogenenic placodes (trigeminal, otic, lateral line and epibranchial placodes) appear to have emerged at a later time (Shimeld and Holland, 2000)[NBK53171] synonym: "neurogenic placodes" EXACT PLURAL [ZFA:0001309] synonym: "placodae neurogenicae" RELATED LATIN [Wikipedia:Neurogenic_placodes] is_a: UBERON:0002546 {source="cjm"} ! cranial placode xref: ZFA:0001309 ! neurogenic placode xref: TAO:0001309 ! neurogenic placode xref: EFO:0003460 ! neurogenic placode [Term] id: UBERON:0007497 name: developing epithelial placode alt_id: EHDAA2:0003112 def: "A domain of columnar epithelium in an embryo that represents the early stage of the development of the epithelial component of a new anatomical structure." [AEO:0000218, JB:DEF] comment: Consider merging with ectodermal placode? In EHDAA2 this includes lens, nasal, otic epibranchial and trigeminal placodes xref: AEO_RETIRED:0000112 ! epithelial placode xref: AEO:0000218 ! developing epithelial placode xref: EHDAA2_RETIRED:0003112 ! developing epithelial placode synonym: "epithelial placode" EXACT [AEO:0000112] is_a: UBERON:0000485 {source="AEO"} ! simple columnar epithelium is_a: UBERON:0001048 ! primordium intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_into UBERON:0000061 ! anatomical structure relationship: has_part CL:0000075 {source="AEO"} ! columnar/cuboidal epithelial cell [Term] id: UBERON:0005088 name: sebaceous gland placode def: "A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud[GO]." [GO:0060791] comment: todo - add bud is_a: UBERON:0011814 {source="NBK53175"} ! non-neurogenic ectodermal placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: develops_into UBERON:0001821 ! sebaceous gland relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer [Term] id: UBERON:0005089 name: sweat gland placode def: "An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud[GO]." [GO:0060793] comment: todo - add bud is_a: UBERON:0011814 {source="NBK53175"} ! non-neurogenic ectodermal placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: develops_into UBERON:0001820 ! sweat gland relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer [Term] id: UBERON:0005091 name: left horn of sinus venosus xref: FMA:70321 ! Left horn of sinus venosus xref: VHOG:0000488 ! sinus venosus left horn xref: EHDAA2:0001840 ! sinus venosus left horn xref: EMAPA:16238 ! left horn xref: EHDAA:482 ! left horn is_a: UBERON:0002050 {source="FMA"} ! embryonic structure relationship: in_left_side_of UBERON:0002063 ! sinus venosus synonym: "sinus venosus left horn" EXACT [VHOG:0000488] property_value: homology_notes "Three major adaptations, or 'novel cardiac components', that were not present in the ancestor chordate heart tube can be distinguished in the lower vertebrate heart: the atrium, ventricle, and possibly the muscular sinus venosus.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000488", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM\, Christoffels VM\, Cardiac Chamber Formation: Development\, Genes\, and Evolution. Physiological Reviews (2003)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005092 name: right horn of sinus venosus xref: FMA:70318 ! Right horn of sinus venosus xref: VHOG:0000489 ! sinus venosus right horn xref: EHDAA2:0001841 ! sinus venosus right horn xref: EMAPA:16239 ! right horn xref: EHDAA:484 ! right horn is_a: UBERON:0002050 {source="FMA"} ! embryonic structure relationship: in_right_side_of UBERON:0002063 ! sinus venosus synonym: "sinus venosus right horn" EXACT [VHOG:0000489] property_value: homology_notes "Three major adaptations, or 'novel cardiac components', that were not present in the ancestor chordate heart tube can be distinguished in the lower vertebrate heart: the atrium, ventricle, and possibly the muscular sinus venosus.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000489", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM\, Christoffels VM\, Cardiac Chamber Formation: Development\, Genes\, and Evolution. Physiological Reviews (2003", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005093 name: cement gland def: "A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm[XAO]." [GO:0071570, XAO:0000033] xref: XAO:0000033 ! cement gland xref: BTO:0002738 ! cement gland is_a: UBERON:0002530 ! gland is_a: UBERON:0002050 ! embryonic structure xref: AAO:0010373 ! cement gland subset: organ_slim property_value: external_definition "A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010373", date_retrieved="2012-06-20", source="AAO:BJB"} [Term] id: UBERON:0005094 ! beak name: beak def: "The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary ramaphotheca, mandibular ramaphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus[GO]. The beak, bill or rostrum is an external anatomical structure of birds which is used for eating and for grooming, manipulating objects, killing prey, probing for food, courtship and feeding young. The term beak is also used to refer to a similar mouthpart in some Ornithischian dinosaurs, monotremes, cephalopods, cetaceans, pufferfishes, turtles, Anuran tadpoles and sirens[WP]." [GO:0071728, Wikipedia:Beak] comment: TODO - add superclass synonym: "avian beak" EXACT [] synonym: "bill" RELATED [] synonym: "rostrum" RELATED [] xref: MESH:A13.114 ! beak is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0010012 ! upper beak name: upper beak is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0005094 ! beak relationship: part_of UBERON:0001709 ! upper jaw region synonym: "upper mandible" RELATED SENSU [] synonym: "maxillary beak" RELATED [] synonym: "rostrum maxillare" RELATED [] [Term] id: UBERON:0010013 ! lower beak name: lower beak is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0005094 ! beak relationship: part_of UBERON:0001710 ! lower jaw region synonym: "lower mandible" RELATED SENSU [] synonym: "mandibular beak" RELATED [] synonym: "rostrum mandibulare" RELATED [] [Term] id: UBERON:0007330 ! rhamphotheca name: rhamphotheca def: "thin keratinized layer of epidermis projecting from outer surface of beak[WP]." [Wikipedia:Beak#Rhamphotheca] comment: Development notes: This covering arises from the Malpighian cells of the bird's epidermis,[9] growing from plates at the base of each mandible[WP] synonym: "horny sheath of beak" RELATED [] synonym: "outer keratin layer of beak" RELATED [] is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0005094 ! beak relationship: part_of UBERON:0001003 ! epidermis [Term] id: UBERON:0007331 name: maxillary rhamphotheca synonym: "maxillary beak" RELATED [] synonym: "rhinotheca" RELATED [Wikipedia:Beak#Rhamphotheca] intersection_of: UBERON:0007330 ! rhamphotheca intersection_of: part_of UBERON:0010012 ! upper beak def: "A rhamphotheca that is part of a upper beak." [OBOL:automatic] [Term] id: UBERON:0007332 name: mandibular rhamphotheca synonym: "mandibular beak" RELATED [] synonym: "gnathotheca" RELATED [Wikipedia:Beak#Rhamphotheca] intersection_of: UBERON:0007330 ! rhamphotheca intersection_of: part_of UBERON:0010013 ! lower beak def: "A rhamphotheca that is part of a lower beak." [OBOL:automatic] [Term] id: UBERON:0012447 name: podotheca def: "A horny sheath covering the lower leg of some birds." [] is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0001003 ! epidermis relationship: part_of UBERON:0002103 ! hindlimb relationship: has_part UBERON:0007381 ! epidermal scale [Term] id: UBERON:0005097 name: renal connecting tubule def: "The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]." [GO:0072027, Wikipedia:Connecting_tubule] synonym: "connecting tubule" EXACT [MA:0002610] xref: MA:0002610 ! renal connecting tubule xref: EMAPA:27758 ! renal connecting tubule of s-shaped body of early tubule of metanephros of urinary system xref: EMAPA:27790 ! renal connecting tubule of renal tubule xref: EMAPA:27865 ! renal connecting tubule of s-shaped body of early tubule of metanephros of urinary system xref: EMAPA:28011 ! renal connecting tubule of cortical renal tubule xref: BTO:0004539 ! connecting tubule is_a: UBERON:0007685 ! region of nephron tubule relationship: develops_from UBERON:0003220 {source="Wikipedia"} ! metanephric mesenchyme synonym: "tubulus renalis arcuatus" RELATED LATIN [Wikipedia:Connecting_tubule] xref: http://upload.wikimedia.org/wikipedia/commons/2/27/Gray1128.png synonym: "kidney connecting tubule" EXACT [MA:0002610] [Term] id: UBERON:0005099 name: short descending thin limb def: "The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology[GO]." [GO:0072063] comment: TODO - epithelium types is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0001285 ! nephron relationship: has_part CL:0000076 ! squamous epithelial cell [Term] id: UBERON:0005100 name: long descending thin limb def: "The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla[GO]." [GO:0072064] is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0001285 ! nephron [Term] id: UBERON:0005101 name: early distal convoluted tubule def: "The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive[GO]." [GO:0072067] xref: EMAPA:28393 ! distal convoluted tubule (also: UBERON:0001292 'distal convoluted tubule') (also: UBERON:0005102 'late distal convoluted tubule') is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0001292 ! distal convoluted tubule [Term] id: UBERON:0005102 name: late distal convoluted tubule def: "The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]." [GO:0072068] comment: TODO - CL xref: EMAPA:28393 ! distal convoluted tubule (also: UBERON:0001292 'distal convoluted tubule') (also: UBERON:0005101 'early distal convoluted tubule') is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0001292 ! distal convoluted tubule [Term] id: UBERON:0006337 name: distal early tubule def: "Portion of the renal tubule which is just posterior to the proximal straight tubule." [ZFA:0005293] comment: in XAO this is pronephric; in ZFA it is an adult structure. we treat it here as generic. consider placing XAO under proneprhic subclass. check relationship with EDCT. subset: vertebrate_core xref: XAO:0000287 ! early distal tubule xref: ZFA:0005293 ! distal early tubule xref: EMAPA:27788 ! early distal tubule of renal tubule xref: EMAPA:28007 ! early distal tubule of cortical renal tubule xref: EMAPA:28390 ! early distal tubule of renal distal tubule is_a: UBERON:0007685 ! region of nephron tubule xref: AAO:0011034 ! early distal tubule xref: TAO:0005293 ! distal early tubule property_value: external_definition "Portion of the pronephric tubule that is immediately posterior to the late proximal tubule.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011034", date_retrieved="2012-06-20", source="XAO:curator"} [Term] id: UBERON:0005892 name: mesonephric early distal tubule def: "The mesonephric equivalent of the ascending limb, or straight distal segment, of metanephric nephrons." [XB:curator] synonym: "mesonephric ascending limb" RELATED [XAO:0000333] synonym: "mesonephric straight distal segment" RELATED [XAO:0000333] xref: XAO:0000333 ! mesonephric early distal tubule is_a: UBERON:0000083 ! mesonephric tubule relationship: develops_from UBERON:0005322 ! mesonephric nephron xref: AAO:0010391 ! mesonephric early distal tubule [Term] id: UBERON:0005103 name: mesonephric epithelium def: "An epithelium that is part of a mesonephros [Automatically generated definition]." [OBOL:automatic] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005104 name: anterior mesonephric tubule def: "." [GO:0072165] synonym: "cranial mesonephric tubule" EXACT [EMAPA:30562] xref: EMAPA:30562 ! cranial mesonephric tubule xref: EMAPA:30576 ! cranial mesonephric tubule is_a: UBERON:0000083 ! mesonephric tubule [Term] id: UBERON:0005105 name: posterior mesonephric tubule def: "." [GO:0072166] synonym: "caudal mesonephric tubule" EXACT [EMAPA:30574] xref: EMAPA:30571 ! caudal mesonephric tubule of mesonephric tubule of mesonephros of genitourinary system xref: EMAPA:30574 ! caudal mesonephric tubule of mesonephric tubule of mesonephros of reproductive system is_a: UBERON:0000083 ! mesonephric tubule [Term] id: UBERON:0005106 name: metanephric tubule def: "A metanephric tubule is an epithelial tube that is part of the metanephros[GO]." [GO:0072173] xref: VHOG:0001526 ! metanephric tubule intersection_of: UBERON:0003914 ! epithelial tube intersection_of: part_of UBERON:0000081 ! metanephros property_value: homology_notes "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {external_class="VHOG:0001526", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.543", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005107 ! metanephric cap name: metanephric cap def: "The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip[GO]. Mesenchyme closely apposed to the tips of the buds is called cap mesenchyme; it will later go on to form nephrons etc[GUDMAP]." [GO:0072185, http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] comment: TODO - check EMAPA synonym: "cap mesenchyme" EXACT [EMAPA:27621] xref: EMAPA:27621 ! cap mesenchyme of metanephric mesenchyme of metanephros of urinary system xref: MA:0002997 ! cap mesenchyme is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003220 ! metanephric mesenchyme relationship: surrounds UBERON:0000084 ! ureteric bud [Term] id: UBERON:0005108 name: metanephric epithelium def: "An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure[GO]." [GO:0072207] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005109 name: metanephric smooth muscle tissue def: "Any smooth muscle tissue that is part of a metanephros." [UBERON:cjm, GO:0072208] intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005111 name: metanephric pyramid def: "Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts[GO]." [GO:0072211] intersection_of: UBERON:0004200 ! kidney pyramid intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005114 name: metanephric ascending thin limb def: "The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent[GO]." [GO:0072218] intersection_of: UBERON:0004193 ! ascending thin limb intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005129 {source="reference_0000032"} ! metanephric distal tubule [Term] id: UBERON:0005115 name: metanephric cortical collecting duct def: "The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]." [GO:0072219] intersection_of: UBERON:0004203 ! cortical collecting duct intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004737 {is_inferred="true", source="reference_0000032"} ! metanephric collecting duct relationship: part_of UBERON:0010533 {is_inferred="true", source="reference_0000032"} ! metanephros cortex [Term] id: UBERON:0005116 name: metanephric descending thin limb def: "It extends to the tip of the metanephric loop of Henle[GO]." [GO:0072220] intersection_of: UBERON:0005096 ! descending thin limb intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005130 {is_inferred="true", source="reference_0000032"} ! metanephric loop of Henle [Term] id: UBERON:0005117 name: metanephric distal convoluted tubule def: "The metanephric distal convoluted tubule is a portion of the metanephric nephron tubule that connects the metanephric loop of Henle to the collecting duct[GO]." [GO:0072221] intersection_of: UBERON:0001292 ! distal convoluted tubule intersection_of: part_of UBERON:0000081 ! metanephros xref: VHOG:0001569 ! metanephric distal convoluted tubule relationship: part_of UBERON:0010533 {is_inferred="true", source="reference_0000032"} ! metanephros cortex relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005118 name: metanephric early distal convoluted tubule def: "The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive[GO]." [GO:0072222] intersection_of: UBERON:0005101 ! early distal convoluted tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005117 {is_inferred="true", source="reference_0000032"} ! metanephric distal convoluted tubule relationship: part_of UBERON:0005129 {source="reference_0000032"} ! metanephric distal tubule [Term] id: UBERON:0005119 name: metanephric glomerular mesangium def: "The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus[GO]." [GO:0072223] intersection_of: UBERON:0002320 ! glomerular mesangium intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005133 {is_inferred="true", source="reference_0000032"} ! metanephric glomerulus vasculature [Term] id: UBERON:0005120 name: metanephric late distal convoluted tubule def: "The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]." [GO:0072225] intersection_of: UBERON:0005102 ! late distal convoluted tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005117 {is_inferred="true", source="reference_0000032"} ! metanephric distal convoluted tubule relationship: part_of UBERON:0005129 {source="reference_0000032"} ! metanephric distal tubule [Term] id: UBERON:0005121 name: metanephric long descending thin limb bend def: "The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros[GO]." [GO:0072226] intersection_of: UBERON:0004206 ! long descending thin limb bend intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005122 name: metanephric macula densa def: "The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus[GO]." [GO:0072227] intersection_of: UBERON:0002335 ! macula densa intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004738 {is_inferred="true", source="reference_0000032"} ! metanephric juxtaglomerular apparatus [Term] id: UBERON:0005123 name: metanephric prebend segment def: "The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability[GO]." [GO:0072228] intersection_of: UBERON:0004207 ! prebend segment intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005116 {is_inferred="true", source="reference_0000032"} ! metanephric descending thin limb [Term] id: UBERON:0005124 name: metanephric proximal convoluted tubule def: "The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule[GO]." [GO:0072229] intersection_of: UBERON:0001287 ! proximal convoluted tubule intersection_of: part_of UBERON:0000081 ! metanephros xref: VHOG:0001570 ! metanephric proximal convoluted tubule relationship: part_of UBERON:0010533 {is_inferred="true", source="reference_0000032"} ! metanephros cortex relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005125 name: metanephric proximal straight tubule def: "The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule[GO]." [GO:0072230] comment: todo - place mammalian xrefs here rather than at parent intersection_of: UBERON:0001290 ! proximal straight tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: homologous_to XAO:0000332 {source="XAO"} ! mesonephric late proximal tubule relationship: part_of UBERON:0005151 {is_inferred="true", source="reference_0000032"} ! metanephric proximal tubule relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron relationship: part_of UBERON:0010533 {source="reference_0000032"} ! metanephros cortex [Term] id: UBERON:0005126 name: metanephric S1 def: "The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]." [GO:0072231] intersection_of: UBERON:0004196 ! S1 portion of tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005124 {is_inferred="true", source="reference_0000032"} ! metanephric proximal convoluted tubule [Term] id: UBERON:0005127 name: metanephric thick ascending limb def: "At the macula densa, the thick ascending limb connects to the distal convoluted tubule[GO]." [GO:0072233] intersection_of: UBERON:0001291 ! thick ascending limb of loop of Henle intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005130 name: metanephric loop of Henle def: "The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros[GO]." [GO:0072236] intersection_of: UBERON:0001288 ! loop of Henle intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004136 ! intermediate tubule relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005132 name: metanephric long nephron def: "Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros[GO]." [GO:0072238] intersection_of: UBERON:0004194 ! long nephron intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005133 name: metanephric glomerulus vasculature alt_id: UBERON:0005143 def: "The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus[GO]." [GO:0072239] intersection_of: UBERON:0004190 ! glomerulus vasculature intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004736 {is_inferred="true", source="reference_0000032"} ! metanephric glomerulus [Term] id: UBERON:0005134 name: metanephric nephron epithelium def: "The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]." [GO:0072243] intersection_of: UBERON:0004211 ! nephron epithelium intersection_of: part_of UBERON:0000081 ! metanephros relationship: surrounds UBERON:0001285 ! nephron relationship: part_of UBERON:0005110 {is_inferred="true", source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005135 name: metanephric glomerular epithelium def: "A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros[GO]." [GO:0072244] intersection_of: UBERON:0004188 ! glomerular epithelium intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004736 {is_inferred="true", source="reference_0000032"} ! metanephric glomerulus relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005136 name: metanephric glomerular endothelium def: "The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros[GO]." [GO:0072264] intersection_of: UBERON:0004189 ! glomerular endothelium intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004736 {is_inferred="true", source="reference_0000032"} ! metanephric glomerulus relationship: part_of UBERON:0005133 {is_inferred="true", source="reference_0000032"} ! metanephric glomerulus vasculature relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005137 name: metanephric capsule alt_id: UBERON:0005112 def: "The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage[GO]." [GO:0072213] intersection_of: UBERON:0002015 ! kidney capsule intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0006170 name: mesonephric capsule def: "The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GO:0061285, GOC:mtg_kidney_jan10] intersection_of: UBERON:0002015 ! kidney capsule intersection_of: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005139 name: metanephric long descending thin limb def: "The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla[GO]." [GO:0072269] intersection_of: UBERON:0005100 ! long descending thin limb intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005110 {is_inferred="true", source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005140 name: metanephric short nephron def: "Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb[GO]." [GO:0072270] intersection_of: UBERON:0004195 ! short nephron intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005141 name: metanephric short descending thin limb def: "The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology[GO]." [GO:0072271] intersection_of: UBERON:0005099 ! short descending thin limb intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005110 {is_inferred="true", source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005144 name: metanephric glomerular capillary def: "This process pertains to the initial formation of a structure from unspecified parts[GO]." [GO:0072277] intersection_of: UBERON:0004212 ! glomerular capillary intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004736 {is_inferred="true", source="reference_0000032"} ! metanephric glomerulus relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005145 name: metanephric comma-shaped body def: "The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]." [GO:0072278] intersection_of: UBERON:0004198 ! comma-shaped body intersection_of: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005149 name: metanephric connecting tubule def: "The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros[GO]." [GO:0072286] intersection_of: UBERON:0005097 ! connecting tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005129 name: metanephric distal tubule alt_id: UBERON:0005150 def: "The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule[GO]." [GO:0072235] intersection_of: UBERON:0004135 ! distal tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005151 name: metanephric proximal tubule alt_id: UBERON:0005131 def: "The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology[GO]." [GO:0072288] intersection_of: UBERON:0004134 ! proximal tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0010533 {is_inferred="true", source="reference_0000032"} ! metanephros cortex relationship: part_of UBERON:0005110 {source="reference_0000032"} ! metanephric nephron [Term] id: UBERON:0005154 ! epithelial cord name: epithelial cord def: "A cord of epithelial cells without a lumen and usually several cells thick." [AEO:0000216] is_a: UBERON:0000486 {source="AEO"} ! multilaminar epithelium xref: EHDAA2:0004052 ! epithelial cord xref: AEO:0000216 ! epithelial cord [Term] id: UBERON:0005157 ! epithelial fold name: epithelial fold def: "An epithelial sheet bent on a linear axis." [GO:0060571] is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0010136 name: epithelial sheet def: "An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GO:0002011] is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0010137 name: polarized epithelium def: "A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis." [GO:0001738] is_a: UBERON:0000483 ! epithelium property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000001" xsd:anyURI [Term] id: UBERON:0005158 name: parenchyma of central nervous system def: "A parenchyma that is part of a central nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "central nervous system parenchyma" EXACT [OBOL:automatic] synonym: "CNS parenchyma" EXACT [OBOL:automatic] synonym: "parenchyma of CNS" EXACT [OBOL:automatic] synonym: "parenchyma of central nervous system" EXACT [] intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0005160 name: vestigial structure is_a: UBERON:0000061 ! anatomical structure [Term] id: UBERON:0005161 name: pelvic spur def: "Pelvic spurs are the externally visible portion of the vestigial remnants of legs found on each side of the vent in primitive snakes, such as boas and pythons. The remnants of a pelvis and femur, which have no connection with the spine, simply 'float' in the muscle mass. The femur protrudes from the snake's body and is covered by a corneal spur, which resembles a claw. Males' spurs are generally longer and more pointed than females', and are used for clasping and tickling during courtship and mating, as well as combat with other males in some species" [Wikipedia:Pelvic_spur] comment: This class refers to the external portion and its corneal covering rather than the combined pelvis plus femur. synonym: "anal spur" RELATED [Wikipedia:Anal_spur] synonym: "cloacal spur" RELATED [] is_a: UBERON:0005160 ! vestigial structure is_a: UBERON:0000026 ! appendage relationship: only_in_taxon NCBITaxon:8570 {source="Wikipedia"} ! Serpentes [Term] id: UBERON:0012446 name: cloacal spur def: "retained pelvic vestiges found in birds. They are generally used in courtship and are more pronounced in males than females." [http://en.wikivet.net] is_a: UBERON:0005160 ! vestigial structure relationship: part_of BERON:0002355 ! pelvis [Term] id: UBERON:0005162 name: multi cell component structure def: "A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part." [CARO:0001000] comment: AO notes: we go with the FMA classification rather than the CARO one. FMA def: "Anatomical cluster which has as direct parts cell parts from two or more cells." subset: upper_level synonym: "multi-cell-component structure" EXACT [CARO:0001000] xref: FMA:83115 ! cell part cluster xref: CARO:0001000 ! multi-cell-component structure xref: FBbt:00007060 ! multi-cell-component structure is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster xref: AAO:0011000 ! multi-cell-component structure synonym: "cell part cluster" RELATED [FMA:83115] [Term] id: UBERON:0011215 name: cell part cluster of neuraxis synonym: "neuraxis layer" EXACT [FMA:83143] intersection_of: UBERON:0005162 ! multi cell component structure intersection_of: part_of UBERON:0001017 ! central nervous system xref: FMA:83143 ! cell part cluster of neuraxis subset: upper_level def: "A multi cell component structure that is part of a central nervous system." [OBOL:automatic] [Term] id: UBERON:0000122 name: neuron projection bundle alt_id: UBERON:0005163 def: "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." [FBC:DOS, FBbt:00005099, CARO:0001001] synonym: "funiculus" EXACT [] synonym: "neural fiber bundle" EXACT [] synonym: "nerve fiber bundle" EXACT [FBbt:00005099] xref: CARO:0001001 xref: FBbt:00005099 ! neuron projection bundle is_a: UBERON:0005162 ! multi-cell-component structure relationship: part_of UBERON:0001016 ! nervous system relationship: has_part GO:0043005 [Term] id: UBERON:0001018 name: axon tract def: "A group of axons linking two or more neuropils and having a common origin, termination[FBbt]." [http://flybrain.uni-freiburg.de/Flybrain/html/terms/terms.html] comment: WP says this is the analog of peripheral nerves in CNS synonym: "axonal tract" EXACT [] synonym: "tract" RELATED [] synonym: "tract of neuraxis" EXACT [FMA:83847] synonym: "neuraxis tract" EXACT [FMA:83847] xref: FBbt:00005100 ! tract xref: FMA:83847 ! Tract of neuraxis xref: EV:0100304 ! tract is_a: UBERON:0000122 ! nerve fiber bundle relationship: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0007699 name: tract of spinal cord synonym: "spinal cord tract" EXACT [FMA:75683] xref: FMA:75683 ! tract of spinal cord intersection_of: UBERON:0001018 ! axon tract intersection_of: part_of UBERON:0002240 ! spinal cord xref: ncithesaurus:Spinal_Cord_Tract ! Spinal Cord Tract def: "An axon tract that is part of a spinal cord." [OBOL:automatic] xref: UMLS:C1519456 [Term] id: UBERON:0007702 name: tract of brain synonym: "brain tract" EXACT [FMA:83848] comment: Editor notes: we place the NIF class here because it is part of the brain xref: FMA:83848 ! tract of brain xref: NIF_GrossAnatomy:birnlex_1649 ! Nerve tract intersection_of: UBERON:0001018 ! axon tract intersection_of: part_of UBERON:0000955 ! brain def: "An axon tract that is part of a brain." [OBOL:automatic] [Term] id: UBERON:0011591 name: tract of diencephalon synonym: "diencephalon tract" EXACT [FMA:62447] intersection_of: UBERON:0001018 ! axon tract intersection_of: part_of UBERON:0001894 ! diencephalon xref: FMA:62447 ! tract of diencephalon def: "An axon tract that is part of a diencephalon." [OBOL:automatic] [Term] id: UBERON:0001019 name: fascicle def: "A slender neuron projection bundle[FBbt]." [Wikipedia:Nervous_system_fascicle] comment: TODO - invert specific? note FBbt class not disjoint from tract. Consider merging with 'neuron projection bundle' subset: uberon_slim synonym: "fasciculus" EXACT [] synonym: "nerve fasciculus" EXACT [FMA:12235] synonym: "nerve bundle" EXACT [FMA:12235] synonym: "neural fasciculus" EXACT [FMA:12235] xref: FBbt:00005101 ! fascicle xref: FMA:12235 ! Nerve fasciculus xref: NIF_GrossAnatomy:birnlex_872 ! Fasciculus xref: ncithesaurus:Fascicle ! Fascicle xref: TGMA:0000088 ! fascicle xref: BTO:0004101 ! fascicle is_a: UBERON:0000122 ! nerve fiber bundle xref: UMLS:C1185741 [Term] id: UBERON:0005837 name: fasciculus of spinal cord synonym: "spinal cord fasciculus" EXACT [FMA:75799] xref: FMA:75799 ! fasciculus of spinal cord intersection_of: UBERON:0001019 ! fascicle intersection_of: part_of UBERON:0002240 ! spinal cord def: "A fascicle that is part of a spinal cord." [OBOL:automatic] [Term] id: UBERON:0005838 name: fasciculus of brain synonym: "brain fasciculus" EXACT [FMA:83844] xref: FMA:83844 ! fasciculus of brain intersection_of: UBERON:0001019 ! fascicle intersection_of: part_of UBERON:0000955 ! brain def: "A fascicle that is part of a brain." [OBOL:automatic] [Term] id: UBERON:0001021 name: nerve def: "an enclosed, cable-like bundle of peripheral axons [wikipedia]. A portion of tissue which is a fasiculated group of axons[ZFA]. Segment of neural tree organ which has as its parts a nerve trunk and its branches; together with other nerves of the same tree it constitutes a neural tree. Examples: chorda tympani, digastric branch of facial nerve, greater petrosal nerve, posterior cutaneous branch of posterior ramus of cervical nerve, superior lateral cutaneous nerve of arm[FMA]." [Wikipedia:Nervous_system, ZFA:0007009, ZFIN:curator, FMA:65132] comment: check nerve vs peripheral nerve vs tract. Check isa hierarchy - we include under neural tissue as well as neuron projection bundle for now. FMA also has this under organ segment subset: uberon_slim subset: vertebrate_core synonym: "neural subtree" RELATED [FMA:65132] xref: BTO:0000925 xref: EHDAA:2851 ! nerve xref: EHDAA:3776 ! nerve xref: EHDAA:4657 ! nerve xref: FBbt:00005105 ! nerve xref: FMA:65132 ! Nerve xref: GAID:758 ! nerve fiber xref: MA:0000217 ! nerve xref: TAO:0007009 ! nerve xref: XAO:0003047 ! nerve xref: ZFA:0007009 ! nerve xref: ncithesaurus:Nerve ! Nerve xref: galen:Nerve ! nerve xref: OpenCyc:Mx4rwP3lkpwpEbGdrcN5Y29ycA ! nerve xref: EHDAA2:0003137 ! nerve xref: AEO:0000137 ! nerve xref: EV:0100162 ! nervous system (also: UBERON:0001016 'nervous system') is_a: UBERON:0003714 {source="EHDAA2"} ! neural tissue is_a: UBERON:0000122 {source="FBbt"} ! neuron projection bundle relationship: part_of UBERON:0000010 ! peripheral nervous system xref: AAO:0011070 ! nerve xref: SCTID:256864008 ! Entire nerve property_value: external_definition "A portion of tissue which is a fasiculated group of axons.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0007009", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "nerves" EXACT PLURAL [TAO:0007009] property_value: has_relational_adjective "nervous" xsd:string xref: UMLS:C0027740 [Term] id: UBERON:0002003 name: peripheral nerve alt_id: UBERON:0003377 def: "Neural tree (organ) which is directly continuous with the neuraxis. Examples: phrenic nerve, radial nerve, ilioinguinal nerve, sciatic nerve[FMA]. The peripheral nerves include the 12 cranial nerves, the spinal nerves and roots, and what are called the autonomic nerves that are concerned specifically with the regulation of the heart muscle, the muscles in blood vessel walls, and glands[BTO]. The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium[GAID]. A peripheral nerve, or simply nerve is an enclosed, cable-like bundle of peripheral axons (the long, slender projections of neurons). A nerve provides a common pathway for the electrochemical nerve impulses that are transmitted along each of the axons. Nerves are found only in the peripheral nervous system. In the central nervous system, the analogous structures are known as tracts[WP]." [Wikipedia:Peripheral_nerve] comment: TODO - check definition vs nerve. See notes for cranial nerve II (optic nerve) subset: uberon_slim subset: major_organ synonym: "peripheral nerve tree" EXACT [] synonym: "nerve part of peripheral nervous system" EXACT [NIF_GrossAnatomy:birnlex_1615] xref: BTO:0001027 xref: FMA:65239 ! Peripheral nerve xref: GAID:747 ! peripheral nerve xref: VHOG:0000901 ! peripheral nerve xref: MA:0000228 ! peripheral nerve xref: XAO:0000204 ! peripheral nerve xref: EMAPA:25148 ! nerve of peripheral nervous system of nervous system of tail of embryo xref: ncithesaurus:Peripheral_Nerve ! Peripheral Nerve xref: NIF_GrossAnatomy:birnlex_1615 ! Nerve part of peripheral nervous system xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Nervous_system_diagram.png/200px-Nervous_system_diagram.png xref: MESH:A08.800.800 ! peripheral nerve xref: EV:0100371 ! peripheral nerve is_a: UBERON:0001021 ! nerve relationship: part_of UBERON:0000010 ! peripheral nervous system relationship: has_developmental_contribution_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest relationship: has_part CL:0002573 ! Schwann cell xref: SCTID:244457007 ! Entire peripheral nerve xref: UMLS:C0031119 [Term] id: UBERON:0003266 name: obsolete nerve of central nervous system comment: obsoleted pending formal definition of nerve, with explicit reference to PNS vs CNS consider: EHDAA:2851 ! nerve consider: EMAPA:17263 ! nerve of central nervous system of nervous system of organ system is_obsolete: true [Term] id: UBERON:0006134 name: nerve fiber def: "A threadlike extension of a nerve cell and consists of an axon and myelin sheath (if existence) in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system (CNS), myelin by oligodendroglia cells is formed. Schwann cells form myelin in the peripheral nervous system (PNS). Schwann cells also make a thin covering in an axon without myelin (in the PNS). A peripheral nerve fiber contains an axon, myelin sheath, schwann cells and its endoneurium. There are no endoneurium and schwann cells in the central nervous system" [Wikipedia:Nervous_system_fiber] synonym: "nerve fibre" EXACT [FMA:5914] synonym: "neurofibrum" EXACT [FMA:5914] xref: FMA:5914 ! nerve fiber xref: MESH:A08.663.542 ! nerve fiber is_a: UBERON:0000470 ! cell part relationship: part_of UBERON:0001019 ! fascicle relationship: has_part GO:0030424 ! axon synonym: "neurofibra" EXACT LATIN [FMA:TA, FMA:5914] xref: SCTID:88545005 ! Nerve fiber synonym: "neurofibra" RELATED LATIN [Wikipedia:Nerve_fiber] [Term] id: UBERON:0011924 name: postganglionic autonomic fiber def: "Nerve fibers which project from cell bodies of autonomic ganglia to synapses on target organs." [MESH:A08.663.542.100, Wikipedia:Postganglionic_nerve_fibers] synonym: "postganglionic autonomic fibre" RELATED [] is_a: UBERON:0006134 ! nerve fiber relationship: part_of UBERON:0002410 ! autonomic nervous system xref: MESH:A08.663.542.100 ! postganglionic autonomic fiber xref: ncithesaurus:Postganglionic_Autonomic_Fiber ! postganglionic autonomic fiber xref: FMA:5924 ! postganglionic nerve fiber synonym: "postganglionic nerve fiber" EXACT [FMA:5924] xref: UMLS:C0004384 [Term] id: UBERON:0011925 name: preganglionic autonomic fiber def: "Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released." [MESH:A08.663.542.122, Wikipedia:Preganglionic_nerve_fibers] synonym: "preganglionic autonomic fibre" RELATED [] is_a: UBERON:0006134 ! nerve fiber relationship: part_of UBERON:0002410 ! autonomic nervous system xref: MESH:A08.663.542.122 ! preganglionic autonomic fiber xref: FMA:5923 ! preganglionic nerve fiber synonym: "preganglionic nerve fiber" EXACT [FMA:5923] [Term] id: UBERON:0011926 name: postganglionic sympathetic fiber def: "A noradrenergic or adrenergic axonal fiber projecting from a sympathetic ganglion to an effector organ" [MP:0008312] synonym: "postganglionic sympathetic fiber" RELATED [MESH:A08.663.542.075.800] synonym: "sympathetic postganglionic fiber" RELATED [MP:0008312] intersection_of: UBERON:0011924 ! postganglionic autonomic nerve fiber intersection_of: part_of UBERON:0000013 ! sympathetic nervous system xref: MESH:A08.663.542.075.800 ! postganglionic sympathetic fiber xref: ncithesaurus:Postganglionic_Sympathetic_Fiber ! postganglionic sympathetic fiber xref: SCTID:323617002 ! Entire postganglionic sympathetic fiber xref: UMLS:C0206254 [Term] id: UBERON:0011927 name: preganglionic sympathetic fiber def: "A cholinergic axonal fiber projecting from the CNS to a sympathetic ganglion" [MP:0008310] synonym: "sympathetic preganglionic fiber" RELATED [MP:0008310] intersection_of: UBERON:0011925 ! preganglionic nerve fiber intersection_of: part_of UBERON:0000013 ! sympathetic nervous system xref: SCTID:323517007 ! Entire preganglionic sympathetic fiber [Term] id: UBERON:0011929 name: postganglionic parasympathetic fiber def: "A cholinergic axonal fiber projecting from a parasympathetic ganglion to an effector organ" [MP:0008313] synonym: "parasympathetic postganglionic fiber" RELATED [MP:0008313] intersection_of: UBERON:0011924 ! postganglionic autonomic fiber intersection_of: part_of UBERON:0000011 ! parasympathetic nervous system xref: MESH:A08.663.542.100.700 ! postganglionic parasympathetic fiber xref: ncithesaurus:Postganglionic_Parasympathetic_Fiber ! postganglionic parasympathetic fiber xref: UMLS:C0206252 [Term] id: UBERON:0011930 name: preganglionic parasympathetic fiber def: "A cholinergic axonal fibers projecting from the CNS to a parasympathetic ganglion" [MP:0008311] synonym: "parasympathetic preganglionic fiber" RELATED [MP:0008311] intersection_of: UBERON:0011925 ! preganglionic nerve fiber intersection_of: part_of UBERON:0000011 ! parasympathetic nervous system [Term] id: UBERON:0006135 name: myelinated nerve fiber comment: consider adding link to UBERON:0002316 ! white matter of neuraxis xref: FMA:5915 ! myelinated nerve fiber xref: GAID:745 ! myelinated nerve fiber xref: MESH:A08.663.542.512 ! myelinated nerve fiber is_a: UBERON:0006134 ! nerve fiber relationship: has_part GO:0043209 ! myelin sheath xref: ncithesaurus:Myelinated_Nerve_Fiber ! Myelinated Nerve Fiber xref: SCTID:362296008 ! Entire myelinated nerve fiber xref: UMLS:C0027750 [Term] id: UBERON:0006136 name: unmyelinated nerve fiber synonym: "non-myelinated nerve fiber" EXACT [FMA:5916] xref: FMA:5916 ! unmyelinated nerve fiber xref: GAID:767 ! unmyelinated nerve fiber xref: MESH:A08.663.542.756 ! unmyelinated nerve fiber is_a: UBERON:0006134 ! nerve fiber xref: ncithesaurus:Unmyelinated_Nerve_Fiber ! Unmyelinated Nerve Fiber xref: SCTID:46920005 ! Non myelinated nerve fiber xref: UMLS:C0501409 [Term] id: UBERON:0006133 ! funiculus name: funiculus of neuraxis def: "The cerebrospinal nerves consist of numerous nerve fibers collected together and enclosed in membranous sheaths. A small bundle of fibers, enclosed in a tubular sheath, is called a funiculus; if the nerve is of small size, it may consist only of a single funiculus; but if large, the funiculi are collected together into larger bundles or fasciculi, which are bound together in a common membranous investment. Examples include: Anterior funiculus of the spinal cord Lateral funiculus of the spinal cord Posterior funiculus of the spinal cord Funiculus solitarius of the medulla Funiculus separans" [Wikipedia:Funiculus_%28neurology%29] xref: FMA:76738 ! Funiculus is_a: UBERON:0000122 ! nerve fiber bundle [Term] id: UBERON:0005172 name: abdomen organ def: "An organ that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] xref: MA:0000522 ! abdomen xref: SCTID:272631008 ! Abdominal organ intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0000916 ! abdomen subset: non_informative [Term] id: UBERON:0005173 name: abdominal segment organ comment: Includes abdomen organ and pelvis organ xref: MA:0000529 intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk subset: non_informative def: "An organ that is part of a abdominal segment of trunk." [OBOL:automatic] [Term] id: UBERON:0005174 name: back organ def: "An organ that is part of a back [Automatically generated definition]." [OBOL:automatic] xref: MA:0001901 intersection_of: UBERON:0000062 intersection_of: part_of UBERON:0001137 subset: organ_slim subset: non_informative [Term] id: UBERON:0005175 name: chest organ def: "An organ that is part of a chest [Automatically generated definition]." [OBOL:automatic] xref: MA:0000552 intersection_of: UBERON:0000062 intersection_of: part_of UBERON:0001443 subset: organ_slim subset: non_informative [Term] id: UBERON:0005177 name: trunk organ def: "An organ that is part of a trunk [Automatically generated definition]." [OBOL:automatic] xref: MA:0000516 intersection_of: UBERON:0000062 intersection_of: part_of UBERON:0002100 subset: organ_slim subset: non_informative [Term] id: UBERON:0005178 name: thoracic cavity organ def: "An organ that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] xref: MA:0000557 intersection_of: UBERON:0000062 intersection_of: located_in UBERON:0002224 subset: non_informative [Term] id: UBERON:0005179 name: pelvis organ def: "An organ that is part of the pelvic region[Automatically generated definition]." [OBOL:automatic] xref: MA:0000543 intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002355 ! pevlis subset: organ_slim subset: non_informative [Term] id: UBERON:0005180 name: obsolete lymph organ def: "An organ that is part of a lymph [Automatically generated definition]." [OBOL:automatic] consider: MA:0000747 is_obsolete: true [Term] id: UBERON:0005181 name: thoracic segment organ synonym: "upper body organ" RELATED [MA:0000563] xref: MA:0000563 intersection_of: UBERON:0000062 intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk subset: non_informative def: "An organ that is part of a thoracic segment of trunk." [OBOL:automatic] [Term] id: UBERON:0005185 name: renal medulla collecting duct def: "A collecting duct of renal tubule that is part of a renal medulla [Automatically generated definition]." [OBOL:automatic] synonym: "medullary collecting duct" EXACT [EMAPA:28061] xref: MA:0002935 xref: EMAPA:28061 ! medullary collecting duct intersection_of: UBERON:0001232 intersection_of: part_of UBERON:0000362 synonym: "kidney medulla collecting duct" EXACT [MA:0002935] [Term] id: UBERON:0005186 name: outer renal medulla collecting duct def: "A collecting duct of renal tubule that is part of a outer medulla of kidney [Automatically generated definition]." [OBOL:automatic] xref: MA:0002599 intersection_of: UBERON:0001232 intersection_of: part_of UBERON:0001293 synonym: "kidney outer medulla collecting duct" EXACT [MA:0002599] [Term] id: UBERON:0005187 name: inner renal medulla collecting duct def: "A collecting duct of renal tubule that is part of a inner medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "papillary collecting duct" RELATED [MA:0002598] xref: MA:0002598 intersection_of: UBERON:0001232 intersection_of: part_of UBERON:0001294 synonym: "kidney inner medulla collecting duct" EXACT [MA:0002598] [Term] id: UBERON:0004358 name: caput epididymis def: "the head of the epididymis" [MP:0002660] comment: Structure notes: The head of the epididymis receives spermatozoa via the efferent ducts of the mediastinum of the testis. It is characterized histologically by a thin myoepithelium. The concentration of the sperm here is dilute[WP] synonym: "caput" BROAD [MP:0002660] synonym: "epidymis head" EXACT [FMA:18259] synonym: "head of epidymis " EXACT [] synonym: "caput epididymidis" RELATED [BTO:0000336] synonym: "head of epididymis" EXACT [FMA:18259] synonym: "epididymal head" EXACT [FMA:18259] synonym: "epididymis head" EXACT [FMA:18259] xref: MA:0002762 ! caput epididymis xref: BTO:0000336 ! caput epididymis xref: EMAPA:19291 ! caput epididymis xref: FMA:18259 ! head of epididymis is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001301 ! epididymis xref: ncithesaurus:Head_of_the_Epididymis ! Head of the Epididymis xref: SCTID:362282002 ! Entire head of epididymis xref: UMLS:C0228023 [Term] id: UBERON:0005188 name: obsolete caput epididymis is_obsolete: true replaced_by: UBERON:0004358 [Term] id: UBERON:0004359 name: corpus epididymis def: "the body of the epididymis" [MP:0002661] synonym: "epididymis body" EXACT [FMA:18260] synonym: "epididymal body" EXACT [FMA:18260] synonym: "epidymis body" EXACT [] synonym: "body of epidymis " EXACT [] synonym: "body of epididymis " EXACT [FMA:18260] synonym: "corpus epididymidis" RELATED [BTO:0000209] synonym: "body of epididymis" EXACT [FMA:18260] xref: MA:0002764 ! corpus epididymis xref: BTO:0000209 ! corpus epididymis xref: FMA:18260 ! body of epididymis xref: EMAPA:19293 ! corpus epididymis is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001301 ! epididymis xref: ncithesaurus:Body_of_the_Epididymis ! Body of the Epididymis xref: SCTID:279620001 ! Entire body of epididymis xref: UMLS:C0228022 [Term] id: UBERON:0005189 name: obsolete corpus epididymis is_obsolete: true replaced_by: UBERON:0004359 [Term] id: UBERON:0004360 name: cauda epididymis def: "the tail of the epididymis" [MP:0002662] comment: Structure notes: This has a thicker myoepithelium than the head region, as it is involved in absorbing fluid to make the sperm more concentrated.[WP] synonym: "epidymis tail" EXACT [] synonym: "corpus" BROAD [MP:0002662] synonym: "epididymis tail" EXACT [FMA:18261] synonym: "epididymal tail" EXACT [FMA:18261] synonym: "tail of epidymis " EXACT [] synonym: "tail of epididymis " EXACT [FMA:18261] synonym: "cauda epididymidis" EXACT [BTO:0000210] synonym: "epididymal cauda" EXACT [BTO:0000210] synonym: "tail of epididymis" EXACT [FMA:18261] xref: BTO:0000210 ! cauda epididymis xref: EMAPA:19292 ! cauda epididymis xref: FMA:18261 ! tail of epididymis xref: MA:0002763 ! cauda epididymis is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001301 ! epididymis xref: ncithesaurus:Tail_of_the_Epididymis ! Tail of the Epididymis xref: SCTID:279621002 ! Entire tail of epididymis xref: UMLS:C0228024 [Term] id: UBERON:0005190 name: obsolete cauda epididymis is_obsolete: true replaced_by: UBERON:0004360 [Term] id: UBERON:0005192 name: deferent duct artery def: "an artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]." [Wikipedia:Artery_to_the_ductus_deferens] synonym: "arteria ductus deferentis" EXACT LATIN [Wikipedia:Artery_to_the_ductus_deferens] synonym: "vas deferens artery" EXACT [] synonym: "ductus deferens artery" EXACT [FMA:18930] synonym: "artery of ductus deferens" EXACT [FMA:18930] xref: FMA:18930 ! artery of ductus deferens xref: MA:0001940 xref: SCTID:279659005 ! Entire ductus deferens artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001000 ! vas deferens relationship: branch_of UBERON:0001310 {source="FMA"} ! umbilical artery relationship: branch_of UBERON:0001312 {source="Wikipedia"} ! superior vesical artery relationship: part_of UBERON:0005352 ! spermatic cord [Term] id: UBERON:0005193 ! ethmoidal artery name: ethmoidal artery def: "One of: anterior or posterior ethmoidal arteries." [Wikipedia:Ethmoidal_arteries] synonym: "ethmoid artery" EXACT [] subset: grouping_class xref: MA:0001949 is_a: UBERON:0001637 {source="MA"} ! artery relationship: part_of UBERON:0000033 ! head relationship: branch_of UBERON:0001619 {source="FMA-abduced"} ! ophthalmic artery union_of: UBERON:0012318 ! anterior ethmoidal artery union_of: UBERON:0012319 ! posterior ethmoidal artery xref: ncithesaurus:Ethmoidal_Artery ! Ethmoidal Artery xref: SCTID:244222007 ! Entire ethmoidal artery xref: UMLS:C0226184 [Term] id: UBERON:0012318 name: anterior ethmoidal artery def: "The anterior ethmoidal artery, also anterior ethmoid artery is an artery of the head. Once branching from the ophthalmic artery, it accompanies the nasociliary nerve through the anterior ethmoidal canal to supply the anterior and middle ethmoidal cells, frontal sinus, and anterosuperior aspect of the lateral nasal wall[WP]" [Wikipedia:Anterior_ethmoidal_artery] synonym: "anterior ethmoid artery" RELATED [Wikipedia:Anterior_ethmoidal_artery] synonym: "anterior meningeal arteries" RELATED [Wikipedia:Anterior_ethmoidal_artery] synonym: "anterior meningeal artery" RELATED [Wikipedia:Anterior_ethmoidal_artery] synonym: "arteria ethmoidalis anterior" EXACT LATIN [Wikipedia:Anterior_ethmoidal_artery] synonym: "a. ethmoidalis anterior" EXACT LATIN [Wikipedia:Anterior_ethmoidal_artery] is_a: UBERON:0005193 ! ethmoidal artery xref: FMA:49986 ! anterior ethmoidal artery xref: SCTID:312160004 ! Entire anterior ethmoidal artery [Term] id: UBERON:0012319 name: posterior ethmoidal artery def: "The posterior ethmoidal artery is an artery of the head. It is smaller than the anterior ethmoidal artery, branches off from the ophthalmic artery when it reaches the medial wall of the orbit." [Wikipedia:Posterior_ethmoidal_artery] synonym: "posterior ethmoidal vessel" RELATED [Wikipedia:Posterior_ethmoidal_artery] synonym: "arteria ethmoidalis posterior" EXACT LATIN [Wikipedia:Posterior_ethmoidal_artery] synonym: "a. ethmoidalis posterior" EXACT LATIN [Wikipedia:Posterior_ethmoidal_artery] is_a: UBERON:0005193 ! ethmoidal artery xref: FMA:49989 ! posterior ethmoidal artery xref: SCTID:312161000 ! Entire posterior ethmoidal artery [Term] id: UBERON:0005194 name: thoracic vein def: "A vein that is part of a thorax [Automatically generated definition]." [OBOL:automatic] xref: MA:0002235 intersection_of: UBERON:0001638 intersection_of: part_of UBERON:0000915 xref: ncithesaurus:Thoracic_Vein ! Thoracic Vein xref: SCTID:281472008 ! Entire vein of thorax xref: UMLS:C0226629 [Term] id: UBERON:0005195 name: deferent duct vein def: "A vein that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] xref: MA:0002100 intersection_of: UBERON:0001638 intersection_of: part_of UBERON:0001000 [Term] id: UBERON:0005197 name: segmental spinal nerve comment: todo - check synonym: "cervical segmental spinal nerves C1-7" EXACT [EHDAA2:0001822] xref: MA:0000234 xref: VHOG:0000920 ! segmental spinal nerve xref: EHDAA2:0001822 ! segmental spinal nerve xref: EMAPA:16990 ! segmental spinal nerve of nerve of spinal xref: EMAPA:25149 ! segmental spinal nerve of nerve of peripheral nervous system of nervous system of tail of embryo xref: EHDAA:3778 ! segmental spinal nerve is_a: UBERON:0001780 {source="MA"} ! spinal nerve relationship: develops_from UBERON:0000044 {source="EHDAA2"} ! dorsal root ganglion relationship: develops_from UBERON:0001806 {source="EHDAA2"} ! sympathetic ganglion xref: EHDAA2:0001822 ! cervical segmental spinal nerves C1-7 [Term] id: UBERON:0005201 name: obsolete cervical trunk consider: MA:0001937 is_obsolete: true comment: was obsolete as it was defined incorrectly. See Fig97 of The Anatomy of the Laboratory Mouse. May be included in future versions of this ontology that include more detailed relationships and comparisons of the arterial system xref: http://www.informatics.jax.org/cookbook/figures/figure97.shtml [Term] id: UBERON:0002335 name: macula densa def: "The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]." [GO:0072024, Wikipedia:Macula_densa] subset: uberon_slim xref: FMA:86333 ! Macula densa xref: MA:0002603 ! macula densa xref: ncithesaurus:Macula_Densa ! Macula Densa xref: BTO:0003940 ! macula densa is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002303 {source="MA"} ! juxtaglomerular apparatus xref: SCTID:244657003 ! Entire macula densa xref: UMLS:C0227662 [Term] id: UBERON:0005202 name: distal straight tubule macula densa def: "A macula densa that is part of an ascending limb of loop of Henle [Automatically generated definition]." [OBOL:automatic] comment: todo - unify terminology - check DST = TAL? Note EMAPA class appears to refer to this segment xref: MA:0002604 ! distal straight tubule macula densa xref: EMAPA:28399 ! macula densa intersection_of: UBERON:0002335 ! macula densa intersection_of: part_of UBERON:0001291 ! thick ascending limb of loop of Henle relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle relationship: part_of UBERON:0006853 {source="MA"} ! renal cortex tubule [Term] id: UBERON:0003546 name: distal convoluted tubule macula densa def: "A macula densa that is part of a distal convoluted tubule [Automatically generated definition]." [OBOL:automatic] xref: MA:0001668 ! distal convoluted tubule macula densa intersection_of: UBERON:0002335 ! macula densa intersection_of: part_of UBERON:0001292 ! distal convoluted tubule relationship: part_of UBERON:0001292 {source="MA"} ! distal convoluted tubule relationship: part_of UBERON:0002335 {source="MA"} ! macula densa [Term] id: UBERON:0005203 name: trachea gland def: "A gland that is part of a submucosa of trachea [Automatically generated definition]." [OBOL:automatic] synonym: "glandula trachealis" EXACT [FMA:7473] synonym: "tubular seromucous gland of trachea" RELATED [FMA:7473] xref: MA:0002937 xref: FMA:7473 ! tracheal gland intersection_of: UBERON:0002530 intersection_of: part_of UBERON:0002202 ! submucosa of trachea xref: SCTID:197423006 ! Entire tracheal gland subset: organ_slim synonym: "tracheal gland" EXACT [FMA:7473] [Term] id: UBERON:0005204 name: larynx submucosa gland def: "A gland that is part of a larynx submucosa [Automatically generated definition]." [OBOL:automatic] xref: MA:0002729 intersection_of: UBERON:0002530 intersection_of: part_of UBERON:0004778 subset: organ_slim [Term] id: UBERON:0005205 name: vagina stroma xref: MA:0002737 intersection_of: UBERON:0003891 intersection_of: part_of UBERON:0000996 def: "A stroma that is part of a vagina." [OBOL:automatic] [Term] id: UBERON:0005206 name: choroid plexus stroma def: "A stroma that is part of a choroid plexus [Automatically generated definition]." [OBOL:automatic] xref: MA:0000825 intersection_of: UBERON:0003891 intersection_of: part_of UBERON:0001886 [Term] id: UBERON:0005207 name: tonsil capsule def: "A capsule that is part of a tonsil [Automatically generated definition]." [OBOL:automatic] xref: MA:0000776 intersection_of: UBERON:0003893 intersection_of: part_of UBERON:0002372 [Term] id: UBERON:0006675 name: venous valve synonym: "valve of vein" EXACT [FMA:68095] xref: FMA:68095 ! Venous valve intersection_of: UBERON:0003978 ! valve intersection_of: part_of UBERON:0001638 ! vein def: "A valve that is part of a vein." [OBOL:automatic] [Term] id: UBERON:0005208 name: right atrium valve def: "A valve that is part of a right atrium [Automatically generated definition]." [OBOL:automatic] xref: MA:0001871 ! right atrium valve xref: EMAPA:17327 ! valve of right atrium synonym: "valve of right atrium" EXACT [EMAPA:17327] synonym: "right atrium valves" RELATED PLURAL [EHDAA2:0000302] intersection_of: UBERON:0003978 intersection_of: part_of UBERON:0002078 xref: EHDAA2:0000302 ! right atrium valves [Term] id: UBERON:0010189 name: right atrium venous valve comment: AO notes: part_of in EHDAA2. Only child in MA. is_a: UBERON:0005208 {source="MA"} ! right atrium valve xref: MA:0001872 ! right atrium venous valve xref: EHDAA2:0001762 ! right venous valve xref: EMAPA:17010 ! venous valve of valve of right part xref: EMAPA:17328 ! venous valve of valve of right atrium synonym: "right venous valve" RELATED [EHDAA2:0001762] [Term] id: UBERON:0005212 name: testis interstitial tissue def: "The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.." [MESH:A05.360.444.849] synonym: "interstitium of the testis" EXACT [EMAPA:18687] synonym: "interstitium of testis" EXACT [UBERON:cjm] synonym: "testis interstitium" EXACT [UBERON:cjm] synonym: "testis - interstitial" EXACT [UBERON:cjm] xref: MA:0002713 intersection_of: UBERON:0005169 intersection_of: part_of UBERON:0000473 relationship: composed_primarily_of CL:0000178 ! Leydig cell xref: SCTID:362280005 ! Entire interstitial tissue of testis xref: EMAPA:18687 ! interstitium of the testis [Term] id: UBERON:0005213 name: outer renal medulla interstitium def: "A portion of interstitial tissue that is part of a outer medulla of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "outer medullary interstitium" EXACT [EMAPA:28337] xref: MA:0002621 ! kidney outer medulla interstitium intersection_of: UBERON:0005169 ! interstitial tissue intersection_of: part_of UBERON:0001293 ! outer medulla of kidney relationship: part_of UBERON:0001293 {source="MA"} ! outer medulla of kidney relationship: part_of UBERON:0005211 {source="MA"} ! renal medulla interstitium xref: EMAPA:28337 ! outer medullary interstitium synonym: "kidney outer medulla interstitium" EXACT [MA:0002621] [Term] id: UBERON:0005214 name: inner renal medulla interstitium def: "A portion of interstitial tissue that is part of a inner medulla of kidney [Automatically generated definition]." [OBOL:automatic] xref: MA:0002620 ! kidney inner medulla interstitium synonym: "inner medullary interstitium" EXACT [EMAPA:28364] intersection_of: UBERON:0005169 ! interstitial tissue intersection_of: part_of UBERON:0001294 ! inner medulla of kidney relationship: part_of UBERON:0001294 {source="MA"} ! inner medulla of kidney relationship: part_of UBERON:0005211 {source="MA"} ! renal medulla interstitium xref: EMAPA:28364 ! inner medullary interstitium synonym: "kidney inner medulla interstitium" EXACT [MA:0002620] [Term] id: UBERON:0005216 name: optic eminence surface ectoderm def: "An external ectoderm that is part of a optic eminence [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000520 xref: RETIRED_EHDAA2:0001311 ! optic eminence surface ectoderm xref: EMAPA:16539 ! surface ectoderm of optic eminence (also: UBERON:0000076 'external ectoderm') intersection_of: UBERON:0000076 intersection_of: part_of UBERON:0004348 relationship: part_of UBERON:0005234 {is_inferred="true", source="reference_0000032"} ! optic eminence ectoderm [Term] id: UBERON:0005217 name: midbrain subarachnoid space def: "A subarachnoid space that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0001304 xref: EMAPA:19055 ! subarachnoid space of meninges of midbrain intersection_of: UBERON:0000315 intersection_of: part_of UBERON:0001891 synonym: "subarachnoid space midbrain" EXACT [VHOG:0001304] synonym: "subarachnoid space mesencephalon" RELATED [VHOG:0001304] property_value: external_definition "Subarachnoid space that is part of the midbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001304", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005218 name: diencephalon subarachnoid space def: "A subarachnoid space that is part of a diencephalon [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0001302 xref: EMAPA:25079 ! subarachnoid space of arachnoid mater of meninges of diencephalon of forebrain intersection_of: UBERON:0000315 intersection_of: part_of UBERON:0001894 synonym: "subarachnoid space diencephalon" EXACT [VHOG:0001302] property_value: external_definition "Subarachnoid space that is part of the diencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001302", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005219 name: hindbrain subarachnoid space def: "A subarachnoid space that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0001303 xref: EMAPA:18211 ! subarachnoid space of meninges of hindbrain of brain of central nervous system of nervous system of organ system intersection_of: UBERON:0000315 intersection_of: part_of UBERON:0002028 synonym: "subarachnoid space hindbrain" EXACT [VHOG:0001303] synonym: "subarachnoid space rhombencephalon" RELATED [VHOG:0001303] property_value: external_definition "Subarachnoid space that is part of the hindbrain. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001303", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005220 name: pancreas head parenchyma def: "A parenchyma that is part of a head of pancreas [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000838 intersection_of: UBERON:0000353 intersection_of: part_of UBERON:0001069 [Term] id: UBERON:0005221 name: liver right lobe parenchyma def: "A parenchyma that is part of a right lobe of liver [Automatically generated definition]." [OBOL:automatic] synonym: "parenchyma of right lobe of liver" EXACT [FMA:71657] xref: VHOG:0000840 xref: FMA:71657 ! Parenchyma of right lobe of liver xref: EHDAA2:0001010 ! liver right lobe parenchyma xref: EMAPA:18317 ! parenchyma of right of lobe of liver intersection_of: UBERON:0000353 intersection_of: part_of UBERON:0001114 [Term] id: UBERON:0005222 name: liver left lobe parenchyma def: "A parenchyma that is part of a left lobe of liver [Automatically generated definition]." [OBOL:automatic] synonym: "parenchyma of left lobe of liver" EXACT [FMA:71658] xref: VHOG:0000839 xref: FMA:71658 ! Parenchyma of left lobe of liver xref: EHDAA2:0001002 ! liver left lobe parenchyma xref: EMAPA:18310 ! parenchyma of left of lobe of liver intersection_of: UBERON:0000353 intersection_of: part_of UBERON:0001115 [Term] id: UBERON:0005223 name: pancreas body parenchyma def: "A parenchyma that is part of a body of pancreas [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000837 xref: EHDAA2:0001370 ! pancreas body parenchyma intersection_of: UBERON:0000353 intersection_of: part_of UBERON:0001150 [Term] id: UBERON:0005224 name: pancreas tail parenchyma def: "A parenchyma that is part of a tail of pancreas [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000469 xref: EHDAA2:0001392 ! pancreas tail parenchyma intersection_of: UBERON:0000353 intersection_of: part_of UBERON:0001151 [Term] id: UBERON:0005225 name: upper leg epithelium def: "An epithelium that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0001041 xref: EHDAA2:0002131 ! upper leg epithelium xref: EMAPA:17500 ! epithelium of upper leg intersection_of: UBERON:0000483 intersection_of: part_of UBERON:0000376 relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm [Term] id: UBERON:0005228 name: upper arm epithelium def: "An epithelium that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000990 xref: EHDAA2:0002113 ! upper arm epithelium xref: EMAPA:17425 ! epithelium of upper arm intersection_of: UBERON:0000483 intersection_of: part_of UBERON:0003822 relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm [Term] id: UBERON:0005229 name: lower leg epithelium def: "An epithelium that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0001050 xref: EHDAA2:0001031 ! lower leg epithelium xref: EMAPA:17497 ! epithelium of lower leg intersection_of: UBERON:0000483 intersection_of: part_of UBERON:0003823 relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm [Term] id: UBERON:0005230 name: obsolete fundus epithelium comment: obsoleted due to confusion between ocular fundus and other types of fundus is_obsolete: true [Term] id: UBERON:0005233 name: medial-nasal process ectoderm def: "An ectoderm that is part of a medial nasal prominence [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000803 xref: EMAPA:16809 ! ectoderm of medial-nasal process is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm intersection_of: UBERON:0000924 intersection_of: part_of UBERON:0004068 xref: EHDAA2:0001078 ! medial nasal process ectoderm [Term] id: UBERON:0009204 name: medial nasal process mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004068 ! medial nasal prominence is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: part_of UBERON:0004068 {source="EHDAA2"} ! medial nasal prominence relationship: develops_from UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest xref: EHDAA2:0001077 ! medial nasal process mesenchyme xref: EMAPA:16810 ! mesenchyme def: "Mesenchyme that is part of a medial nasal prominence." [OBOL:automatic] [Term] id: UBERON:0009205 name: lateral nasal process mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004067 ! lateral nasal prominence relationship: develops_from UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest xref: EHDAA2:0000917 ! lateral nasal process mesenchyme xref: EMAPA:16807 ! mesenchyme of latero-nasal process synonym: "mesenchyme of latero-nasal process" EXACT [EMAPA:16807] def: "Mesenchyme that is part of a lateral nasal prominence." [OBOL:automatic] [Term] id: UBERON:0009206 name: lateral nasal process surface ectoderm synonym: "ectoderm of latero-nasal process" EXACT [EMAPA:16806] intersection_of: UBERON:0000924 intersection_of: part_of UBERON:0004067 ! lateral nasal prominence is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm xref: EHDAA2:0000918 ! lateral nasal process surface ectoderm xref: EMAPA:16806 ! ectoderm of latero-nasal process def: "An ectoderm that is part of a lateral nasal prominence." [OBOL:automatic] [Term] id: UBERON:0005234 name: optic eminence ectoderm def: "An ectoderm that is part of a optic eminence [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0001105 xref: RETIRED_EHDAA2:0001309 ! optic eminence ectoderm xref: EMAPA:16323 ! ectoderm of optic eminence xref: EHDAA:940 ! ectoderm of optic eminence intersection_of: UBERON:0000924 intersection_of: part_of UBERON:0004348 [Term] id: UBERON:0005241 name: obsolete apical ectodermal ridge forelimb def: "A forelimb that is part of an apical ectodermal ridge [Automatically generated definition]." [OBOL:automatic] consider: VHOG:0001064 is_obsolete: true [Term] id: UBERON:0005242 name: obsolete apical ectodermal ridge hindlimb def: "A hindlimb that is part of an apical ectodermal ridge [Automatically generated definition]." [OBOL:automatic] consider: VHOG:0001066 is_obsolete: true [Term] id: UBERON:0005243 name: interventricular septum endocardium def: "An endocardium that is part of a interventricular septum [Automatically generated definition]." [OBOL:automatic] comment: todo - split? synonym: "endocardium of interventricular septum" EXACT [FMA:83584] xref: VHOG:0000615 xref: FMA:83584 ! Endocardium of interventricular septum intersection_of: UBERON:0002165 intersection_of: part_of UBERON:0002094 xref: EHDAA2:0000886 ! muscular interventricular septum endocardium xref: EHDAA2:0000887 ! membranous interventricular septum endocardium synonym: "interventricular septum endocardial tissue" RELATED [VHOG:0000615] [Term] id: UBERON:0005248 name: bulbus cordis myocardium def: "A myocardium that is part of a bulbus cordis [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000609 intersection_of: UBERON:0002349 intersection_of: part_of UBERON:0004706 synonym: "bulbus cordis cardiac muscle" RELATED [VHOG:0000609] [Term] id: UBERON:0005249 name: metanephric renal pelvis xref: VHOG:0000945 ! metanephros pelvis synonym: "metanephros pelvis" EXACT [VHOG:0000945] intersection_of: UBERON:0001224 ! renal pelvis intersection_of: part_of UBERON:0000081 property_value: homology_notes "The ureteric bud itself forms the collecting tubules and the ureter that drain the adult kidney. This type of kidney, called the metanephros, occurs in all adult amniotes.[well established][VHOG]" xsd:string {external_class="VHOG:0000945", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A renal pelvis that is part of a metanephros." [OBOL:automatic] [Term] id: UBERON:0005250 name: stomatodeum gland xref: VHOG:0000658 intersection_of: UBERON:0002530 intersection_of: part_of UBERON:0000930 subset: organ_slim synonym: "stomatodaeum gland" EXACT [VHOG:0000658] def: "A gland that is part of a stomodeum." [OBOL:automatic] [Term] id: UBERON:0005251 name: yolk sac cavity def: "An anatomical cavity that is part of a yolk sac [Automatically generated definition]." [OBOL:automatic] comment: In mammals, the yolk sac cavity contains fluid rather than platelets[Kardong] AO notes: in EHDAA2, there are separate primary and secondary yolk sac cavities synonym: "yolk sac lumen" EXACT [] synonym: "cavity of yolk sac" EXACT [FMA:63942] xref: VHOG:0000843 xref: FMA:63942 ! Cavity of yolk sac xref: EMAPA:16055 ! yolk sac cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: enclosed_by UBERON:0001040 ! yolk sac [Term] id: UBERON:0005254 name: upper leg mesenchyme def: "Mesenchyme that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000506 xref: EHDAA2:0002132 ! upper leg mesenchyme xref: EMAPA:17501 ! mesenchyme of upper leg intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0000376 [Term] id: UBERON:0005256 name: trunk mesenchyme subset: vertebrate_core xref: VHOG:0000281 xref: ZFA:0000081 ! trunk mesenchyme xref: EHDAA2:0002092 ! trunk mesenchyme xref: EMAPA:16177 ! trunk mesenchyme xref: EHDAA:377 ! trunk mesenchyme xref: EFO:0003485 ! trunk mesenchyme intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0002100 xref: TAO:0000081 ! trunk mesenchyme def: "Mesenchyme that is part of a trunk." [OBOL:automatic] [Term] id: UBERON:0007683 name: lateral mesenchyme derived from mesoderm xref: ZFA:0000905 ! lateral mesenchyme derived from mesoderm xref: EMAPA:16409 ! lateral mesenchyme derived from mesoderm xref: EFO:0003590 ! lateral mesenchyme derived from mesoderm is_a: UBERON:0005256 {source="ZFA"} ! trunk mesenchyme xref: TAO:0000905 ! lateral mesenchyme derived from mesoderm [Term] id: UBERON:0005257 name: manual digit mesenchyme def: "Mesenchyme that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit mesenchyme" EXACT [OBOL:accepted] synonym: "manual digital ray mesenchyme" RELATED [UBERON:cjm] synonym: "anterior limb digital ray mesenchyme" RELATED [UBERON:cjm] comment: Editor notes: In EHDAA2, the metacarpal cartilage condensation is considered part of the digits - it might be better to call the whole structure digital ray mesenchyme/condensation xref: VHOG:0001416 xref: EHDAA2:0000407 ! digital region mesenchyme synonym: "finger mesenchyme" EXACT [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002389 ! manual digit relationship: develops_from UBERON:0009523 ! mesenchyme of handplate [Term] id: UBERON:0005258 name: upper arm mesenchyme def: "Mesenchyme that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000505 xref: EHDAA2:0002114 ! upper arm mesenchyme xref: EMAPA:17426 ! mesenchyme of upper arm intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0003822 [Term] id: UBERON:0005259 name: lower leg mesenchyme def: "Mesenchyme that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000752 xref: EHDAA2:0001032 ! lower leg mesenchyme xref: EMAPA:17498 ! mesenchyme of lower leg intersection_of: UBERON:0003104 intersection_of: part_of UBERON:0003823 [Term] id: UBERON:0005261 name: atrium cardiac jelly def: "A cardiac jelly that is part of an atrium [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000941 xref: EMAPA:16690 ! cardiac jelly of common atrial chamber of atrium xref: EMAPA:16814 ! cardiac jelly of left part xref: EMAPA:16821 ! cardiac jelly of right part intersection_of: UBERON:0003906 intersection_of: part_of UBERON:0002081 ! cardiac atrium property_value: external_definition "Cardiac jelly that is part of the atrium. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000941", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005262 name: ventricle cardiac jelly def: "A cardiac jelly that is part of a ventricle [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000943 intersection_of: UBERON:0003906 intersection_of: part_of UBERON:0002082 ! cardiac ventricle property_value: external_definition "Cardiac jelly that is part of the ventricle. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000943", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005263 name: outflow tract cardiac jelly def: "A cardiac jelly that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] xref: VHOG:0000940 xref: EHDAA2:0001354 ! outflow tract cardiac jelly xref: EMAPA:16230 ! cardiac jelly of outflow tract of primitive heart tube xref: EMAPA:16347 ! cardiac jelly of outflow tract of heart intersection_of: UBERON:0003906 intersection_of: part_of UBERON:0004145 property_value: external_definition "Cardiac jelly that is part of the outflow tract. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000940", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005264 name: obsolete midbrain neural fold consider: VHOG:0000793 is_obsolete: true [Term] id: UBERON:0005265 name: obsolete hindbrain neural fold consider: VHOG:0001211 is_obsolete: true [Term] id: UBERON:0005266 name: obsolete spinal cord neural fold consider: VHOG:0000628 is_obsolete: true [Term] id: UBERON:0005267 name: renal cortex collecting duct def: "A collecting duct of renal tubule that is part of a cortex of kidney [Automatically generated definition]." [OBOL:automatic] xref: MA:0002600 intersection_of: UBERON:0001232 intersection_of: part_of UBERON:0001225 synonym: "kidney cortex collecting duct" EXACT [MA:0002600] [Term] id: UBERON:0005268 name: renal cortex artery def: "Artery that supplies renal cortex." [OBOL:automatic] synonym: "renal cortex arterial system" RELATED [MA:0002582] synonym: "renal cortex artery" EXACT [MA:0002582] synonym: "kidney cortex artery" EXACT [MP:0011314] xref: MA:0002582 ! renal cortex artery xref: EMAPA:28035 ! arterial of developing vasculature of cortex intersection_of: UBERON:0001637 intersection_of: supplies UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney [Term] id: UBERON:0005269 name: renal cortex vein def: "Artery that receives blood from the renal cortex[MP, modified]" [MGI:csmith] synonym: "renal cortex venous system" RELATED [MA:0002592] synonym: "kidney cortex vein" RELATED [MP:0011322] xref: MA:0002592 ! kidney cortex vein xref: EMAPA:28152 ! renal cortical venous system intersection_of: UBERON:0001638 intersection_of: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney [Term] id: UBERON:0005215 name: kidney interstitium def: "The interstitium of the kidney comprises the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances. As we define it here, the interstitium is bounded on all sides by tubular and vascular basement membranes." [doi:10.1038/ki.1991.49] xref: MA:0002616 ! kidney interstitium xref: EMAPA:27690 ! renal interstitium xref: FMA:70983 ! stroma of kidney synonym: "renal interstitium" EXACT [FMA:70983] synonym: "renal stroma" EXACT [FMA:70983] is_a: UBERON:0003891 {source="FMA"} ! stroma intersection_of: UBERON:0005169 ! interstitial tissue intersection_of: part_of UBERON:0002113 ! kidney synonym: "stroma of kidney" EXACT [FMA:70983] [Term] id: UBERON:0005211 name: renal medulla interstitium def: "tissue surrounding the loop of Henle in the renal medulla.." [Wikipedia:Bone_marrow_of_ovaryry_interstitium] comment: Function notes: It functions in renal water reabsorption by building up a high hypertonicity, which draws water out of the thin descending limb of the loop of Henle and the collecting duct system. This hypertonicity, in turn, is created by an efflux of urea from the inner medullary collecting duct. synonym: "kidney medulla interstitium" EXACT [MA:0002619] synonym: "renal medullary interstitium" EXACT [EMAPA:18326] xref: MA:0002619 ! kidney medulla interstitium xref: EMAPA:18326 ! renal medullary interstitium intersection_of: UBERON:0005169 ! interstitial tissue intersection_of: part_of UBERON:0000362 ! renal medulla relationship: part_of UBERON:0005215 {source="MA"} ! kidney interstitium [Term] id: UBERON:0005270 name: renal cortex interstitium def: "A portion of interstitial tissue that is part of a cortex of kidney [Automatically generated definition]." [OBOL:automatic] synonym: "kidney cortex interstitium" EXACT [MA:0002608] synonym: "cortical stroma" RELATED [EMAPA:28136] xref: MA:0002608 ! kidney cortex interstitium xref: EMAPA:28136 ! renal cortical interstitium intersection_of: UBERON:0005169 ! interstitial tissue intersection_of: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney relationship: part_of UBERON:0005215 {source="MA"} ! kidney interstitium [Term] id: UBERON:0003919 name: obsolete mesenchyme of adult kidney is_obsolete: true [Term] id: UBERON:0006373 name: perihilar interstitium xref: MA:0002618 ! perihilar interstitium xref: EMAPA:28083 ! perihilar interstitium is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001224 {source="MA"} ! renal pelvis relationship: part_of UBERON:0005215 {source="MA"} ! kidney interstitium [Term] id: UBERON:0005271 name: juxtamedullary cortex def: "the part of the renal cortex nearest to the medulla." [http://medical-dictionary.thefreedictionary.com/juxtamedullary+cortex] synonym: "juxtamedullary cortex of kidney" EXACT [FMA:74288] synonym: "inner cortex of kidney" EXACT [FMA:74288] synonym: "inner renal cortex" EXACT [KUPO:0001008] xref: MA:0001648 ! juxtamedullary cortex xref: FMA:74288 ! inner cortex of kidney xref: KUPO:0001008 ! inner renal cortex is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001225 {source="FMA", source="KUPO"} ! cortex of kidney [Term] id: UBERON:0005272 name: peritubular capillary def: "In the renal system, peritubular capillaries are tiny blood vessels that travel alongside nephrons allowing reabsorption and secretion between blood and the inner lumen of the nephron. Ions and minerals that need to be saved in the body are reabsorbed into the peritubular capillaries through active transport, secondary active transport, or transcytosis. The ions that need to be excreted as waste are secreted from the capillaries into the nephron to be sent towards the bladder and out of the body. The majority of exchange through the peritubular capillaries occurs because of chemical gradients, osmosis and Na+ pumps[WP]." [Wikipedia:Peritubular_capillaries] xref: MA:0002588 ! peritubular capillary is_a: UBERON:0003527 ! kidney capillary relationship: has_function_in GO:0070293 {source="Wikipedia"} ! renal reabsorption [Term] id: UBERON:0009564 ! distal limb integumentary appendage name: distal limb integumentary appendage comment: Consider classifying as something different from appendage def: "A nail, hoof or claw." [PMID:11710767] synonym: "unguis" RELATED [] xref: MESH:A13.491 ! hoof and claw is_a: UBERON:0000026 ! appendage relationship: part_of UBERON:0009551 {source="cjm"} ! distal segment of digit relationship: part_of UBERON:0001003 ! epidermis relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer [Term] id: UBERON:0009565 name: nail of manual digit synonym: "finger nail" EXACT [FMA:54327] synonym: "fingernail" EXACT [FMA:54327] intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0005276 {source="FMA"} ! dorsal skin of finger xref: FMA:54327 ! nail of finger synonym: "nail of finger" EXACT [FMA:54327] xref: ncithesaurus:Fingernail ! Fingernail xref: SCTID:244197001 ! Entire nail of finger synonym: "nail plate of finger" RELATED [FMA:54327] def: "A nail that is part of a manual digit." [OBOL:automatic] relationship: part_of UBERON:0009552 {source="reference_0000032"} ! distal segment of manual digit xref: UMLS:C0222001 [Term] id: UBERON:0011273 name: nail of manual digit 1 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0001463 ! manual digit 1 xref: EMAPA:18734 ! claw of digit 1 of fore-paw synonym: "claw of digit 1 of fore-paw" EXACT [EMAPA:18734] synonym: "nail plate of thumb" EXACT [FMA:54329] synonym: "thumb nail" EXACT [FMA:54329] is_a: UBERON:0009565 {source="FMA"} ! nail of forelimb digit xref: FMA:54329 ! nail of thumb synonym: "nail of thumb" EXACT [FMA:54329] xref: SCTID:181584008 ! Entire nail of thumb def: "A nail that is part of a manual digit 1." [OBOL:automatic] [Term] id: UBERON:0011274 name: nail of manual digit 2 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003622 ! manual digit 2 xref: EMAPA:18735 ! claw of digit 2 of fore-paw synonym: "claw of digit 2 of fore-paw" EXACT [EMAPA:18735] synonym: "index finger nail" EXACT [FMA:54332] synonym: "nail of second finger" EXACT [FMA:54332] synonym: "nail plate of index finger" EXACT [FMA:54332] is_a: UBERON:0009565 {source="FMA"} ! nail of forelimb digit xref: FMA:54332 ! nail of index finger synonym: "nail of index finger" EXACT [FMA:54332] xref: SCTID:181580004 ! Entire nail of index finger def: "A nail that is part of a manual digit 2." [OBOL:automatic] [Term] id: UBERON:0011275 name: nail of manual digit 3 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003623 ! manual digit 3 xref: EMAPA:18736 ! claw of digit 3 of fore-paw synonym: "claw of digit 3 of fore-paw" EXACT [EMAPA:18736] synonym: "middle finger nail" EXACT [FMA:54335] synonym: "nail of third finger" EXACT [FMA:54335] synonym: "nail plate of middle finger" EXACT [FMA:54335] is_a: UBERON:0009565 {source="FMA"} ! nail of forelimb digit xref: FMA:54335 ! nail of middle finger synonym: "nail of middle finger" EXACT [FMA:54335] xref: SCTID:181581000 ! Entire nail of middle finger def: "A nail that is part of a manual digit 3." [OBOL:automatic] [Term] id: UBERON:0011276 name: nail of manual digit 4 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003624 ! manual digit 4 xref: EMAPA:18737 ! claw of digit 4 of fore-paw synonym: "claw of digit 4 of fore-paw" EXACT [EMAPA:18737] synonym: "nail of fourth finger" EXACT [FMA:54338] synonym: "nail plate of ring finger" EXACT [FMA:54338] synonym: "ring finger nail" EXACT [FMA:54338] is_a: UBERON:0009565 {source="FMA"} ! nail of forelimb digit xref: FMA:54338 ! nail of ring finger synonym: "nail of ring finger" EXACT [FMA:54338] xref: SCTID:181582007 ! Entire nail of ring finger def: "A nail that is part of a manual digit 4." [OBOL:automatic] [Term] id: UBERON:0011277 name: nail of manual digit 5 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003625 ! manual digit 5 xref: EMAPA:18738 ! claw of digit 5 of fore-paw synonym: "claw of digit 5 of fore-paw" EXACT [EMAPA:18738] synonym: "little finger nail" EXACT [FMA:54341] synonym: "nail of fifth finger" EXACT [FMA:54341] synonym: "nail plate of little finger" EXACT [FMA:54341] is_a: UBERON:0009565 {source="FMA"} ! nail of forelimb digit xref: FMA:54341 ! nail of little finger xref: SCTID:181583002 ! Entire nail of little finger synonym: "nail of little finger" RELATED [FMA:54341] def: "A nail that is part of a manual digit 5." [OBOL:automatic] [Term] id: UBERON:0009567 name: nail of pedal digit synonym: "toe nail" EXACT [FMA:54328] synonym: "toenail" EXACT [FMA:54328] intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0005277 {source="FMA"} ! dorsal skin of toe xref: FMA:54328 ! nail of toe synonym: "nail of toe" EXACT [FMA:54328] xref: ncithesaurus:Toe_Nail ! Toenail xref: SCTID:244198006 ! Entire nail of toe synonym: "nail plate of toe" RELATED [FMA:54328] def: "A nail that is part of a pedal digit." [OBOL:automatic] relationship: part_of UBERON:0009553 {source="reference_0000032"} ! distal segment of pedal digit xref: UMLS:C0222007 [Term] id: UBERON:0011278 name: nail of pedal digit 1 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003631 ! pedal digit 1 xref: EMAPA:18739 ! claw of digit 1 of hind-paw synonym: "claw of digit 1 of hind-paw" EXACT [EMAPA:18739] synonym: "big toe nail" EXACT [FMA:54344] synonym: "nail of great toe" EXACT [FMA:54344] synonym: "nail plate of big toe" EXACT [FMA:54344] is_a: UBERON:0009567 {source="FMA"} ! nail of hindlimb digit xref: FMA:54344 ! nail of big toe synonym: "nail of big toe" EXACT [FMA:54344] xref: SCTID:181592004 ! Entire nail of great toe def: "A nail that is part of a pedal digit 1." [OBOL:automatic] [Term] id: UBERON:0011279 name: nail of pedal digit 2 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003632 ! pedal digit 2 xref: EMAPA:18740 ! claw of digit 2 of hind-paw synonym: "claw of digit 2 of hind-paw" EXACT [EMAPA:18740] synonym: "nail plate of second toe" EXACT [FMA:54347] synonym: "second toe nail" EXACT [FMA:54347] is_a: UBERON:0009567 {source="FMA"} ! nail of hindlimb digit xref: FMA:54347 ! nail of second toe synonym: "nail of second toe" EXACT [FMA:54347] xref: SCTID:181593009 ! Entire nail of second toe def: "A nail that is part of a pedal digit 2." [OBOL:automatic] [Term] id: UBERON:0011280 name: nail of pedal digit 3 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003633 ! pedal digit 3 xref: EMAPA:18741 ! claw of digit 3 of hind-paw synonym: "claw of digit 3 of hind-paw" EXACT [EMAPA:18741] synonym: "nail plate of third toe" EXACT [FMA:54350] synonym: "third toe nail" EXACT [FMA:54350] is_a: UBERON:0009567 {source="FMA"} ! nail of hindlimb digit xref: FMA:54350 ! nail of third toe synonym: "nail of third toe" EXACT [FMA:54350] xref: SCTID:181594003 ! Entire nail of third toe def: "A nail that is part of a pedal digit 3." [OBOL:automatic] [Term] id: UBERON:0011281 name: nail of pedal digit 4 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003634 ! pedal digit 4 xref: EMAPA:18742 ! claw of digit 4 of hind-paw synonym: "claw of digit 4 of hind-paw" EXACT [EMAPA:18742] synonym: "fourth toe nail" EXACT [FMA:54353] synonym: "nail plate of fourth toe" EXACT [FMA:54353] is_a: UBERON:0009567 {source="FMA"} ! nail of hindlimb digit xref: FMA:54353 ! nail of fourth toe synonym: "nail of fourth toe" EXACT [FMA:54353] xref: SCTID:181595002 ! Entire nail of fourth toe def: "A nail that is part of a pedal digit 4." [OBOL:automatic] [Term] id: UBERON:0011282 name: nail of pedal digit 5 intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003635 ! pedal digit 5 xref: EMAPA:18743 ! claw of digit 5 of hind-paw synonym: "claw of digit 5 of hind-paw" EXACT [EMAPA:18743] synonym: "little toe nail" EXACT [FMA:54356] synonym: "nail of fifth toe" EXACT [FMA:54356] synonym: "nail plate of little toe" EXACT [FMA:54356] is_a: UBERON:0009567 {source="FMA"} ! nail of hindlimb digit xref: FMA:54356 ! nail of little toe synonym: "nail of little toe" EXACT [FMA:54356] xref: SCTID:181596001 ! Entire nail of fifth toe def: "A nail that is part of a pedal digit 5." [OBOL:automatic] [Term] id: UBERON:0001705 name: nail def: "a horn-like keratin structure covering the dorsal aspect of the terminal phalanges of fingers and toes[WP]." [Wikipedia:Nail_(anatomy)] comment: TODO: check claw vs nail. A primate's nail consists of the unguis alone; the subunguis has disappeared. subset: uberon_slim synonym: "claw" NARROW SENSU [Wikipedia:Claw] synonym: "talon" RELATED [] xref: FMA:54326 ! Nail xref: GAID:1320 ! nail xref: MA:0002703 ! nail xref: MAT:0000158 ! nail xref: MIAA:0000158 ! nail xref: XAO:0003103 ! claw xref: OpenCyc:Mx4rvVjJv5wpEbGdrcN5Y29ycA xref: ncithesaurus:Nail ! Nail xref: EFO:0000956 ! nail xref: galen:Nail ! nail xref: VHOG:0001361 ! claw xref: BTO:0001719 ! claw xref: MESH:A17.600 ! nail xref: EV:0100159 ! nail is_a: UBERON:0009564 ! distal limb integumentary appendage relationship: part_of UBERON:0001003 {source="FMA"} ! epidermis relationship: part_of UBERON:0002097 {source="FMA"} ! skin of body relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! skin basal layer xref: SCTID:72651009 ! Nail structure xref: UMLS:C0027342 [Term] id: UBERON:0008198 ! nail plate name: nail plate def: "The nail plate is the hard and translucent portion of the nail, composed of keratin." [https://sourceforge.net/tracker/?func=detail&aid=3307500&group_id=36855&atid=440764, Wikipedia:Nail_plate, http://purl.obolibrary.org/obo/uberon/tracker/20] comment: AO Notes: in FMA, the nail is the nail plate xref: MA:0002708 ! nail plate is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001705 {source="MA"} ! nail xref: ncithesaurus:Nail_Plate ! Nail Plate xref: SCTID:372177002 ! Entire nail plate synonym: "lamina unguis" RELATED LATIN [Wikipedia:Nail_plate] xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/Fingernail_label.jpg [Term] id: UBERON:0002283 name: nail matrix def: "Portion of tissue (or germinal matrix) upon which the nail rests, the part of the nail bed that extends beneath the nail root and contains nerves, lymph and blood vessels. The matrix is responsible for the production of the cells that become the nail plate. The width and thickness of the nail plate is determined by the size, length, and thickness of the matrix, while the shape of the fingertip itself determines if the nail plate is flat, arched, or hooked. The matrix will continue to grow as long as it receives nutrition and remains in a healthy condition. As new nail plate cells are incubated, they emerge from the matrix round and white to push older nail plate cells forward; and in this way yet older cells become compressed, flat, and translucent, making the pink colour of the capillaries in the nail bed below visible[WP]." [UBERON:cjm] subset: uberon_slim synonym: "onychostroma" EXACT [Wikipedia:Nail_(anatomy)#Parts_of_the_nail] synonym: "matrix unguis" EXACT [Wikipedia:Nail_(anatomy)#Parts_of_the_nail] synonym: "keratogenous membrane" EXACT [Wikipedia:Nail_(anatomy)#Parts_of_the_nail] xref: FMA:77856 ! Nail matrix xref: MA:0002707 ! nail matrix is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001705 ! nail [Term] id: UBERON:0004105 name: subungual region def: "Region beneath a nail or claw." [UBERON:cjm] comment: Consider merging with nailbed is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001705 ! nail property_value: has_relational_adjective "subungual" xsd:string [Term] id: UBERON:0005273 ! nail bed name: nail bed def: "Region of skin beneath the nail plate[WP]." [UBERON:gvg] synonym: "nailbed" EXACT [] xref: MA:0002706 ! nail bed xref: VHOG:0001362 ! nail bed xref: EV:0100158 ! nail bed is_a: UBERON:0005275 ! dorsal skin of digit relationship: adjacent_to UBERON:0008198 ! nail plate relationship: part_of UBERON:0001705 {source="MA"} ! nail relationship: part_of UBERON:0004105 ! subungual region xref: SCTID:181578005 ! Entire nail bed [Term] id: UBERON:0005278 name: nail bed of finger def: "A nail bed that is part of a manual digit." [OBOL:automatic] xref: FMA:60348 ! nail bed of finger synonym: "nail bed of finger" EXACT [FMA:60348] is_a: UBERON:0005276 ! dorsal skin of finger intersection_of: UBERON:0005273 ! nail bed intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002389 ! manual digit xref: SCTID:244199003 ! Nail bed of finger [Term] id: UBERON:0005279 name: nail bed of toe def: "A nail bed that is part of a pedal digit." [OBOL:automatic] xref: FMA:60529 ! nail bed of toe synonym: "nail bed of toe" EXACT [FMA:60529] is_a: UBERON:0005277 ! dorsal skin of toe intersection_of: UBERON:0005273 ! nail bed intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0001466 ! pedal digit xref: SCTID:244200000 ! Nail bed of toe [Term] id: UBERON:0005274 name: proximal nail bed xref: MA:0002709 ! proximal nail bed is_a: UBERON:0005275 ! dorsal skin of digit relationship: part_of UBERON:0001705 {source="MA"} ! nail [Term] id: UBERON:0002284 name: hyponychium def: "Epithelium located beneath the nail plate at the junction between the free edge and the skin of the fingertip. It forms a seal that protects the nail bed." [Wikipedia:Hyponychium] subset: uberon_slim xref: FMA:77860 ! Hyponychium xref: MA:0002705 ! hyponychium is_a: UBERON:0000483 ! epithelium relationship: adjacent_to UBERON:0001705 ! nail relationship: part_of UBERON:0002097 ! skin of body xref: SCTID:300918002 ! Entire hyponychium [Term] id: UBERON:0004882 ! eponychium name: eponychium def: "Thickened layer of skin surrounding fingernails and toenails. Beneath the cuticle is a thin layer of a membrane known as the pterygium. The function is to protect the area between the nail and epidermis from exposure to harmful bacteria. The vascularization pattern is similar to that of perionychium. The eponychium is the end of the proximal fold that folds back upon itself to shed an epidermal layer of skin onto the newly formed nail plate. This layer of non-living, almost invisible skin is the cuticle that 'rides out' on the surface of the nail plate. Together, the eponychium and the cuticle form a protective seal. The cuticle on the nail plate is dead cells and is often removed during manicure, but the eponychium is living cells and should not be touched.[6] The perionyx is the projecting edge of the eponychium covering the proximal strip of the lunula[WP]." [Wikipedia:Eponychium] xref: FMA:77859 ! Eponychium xref: MA:0002704 ! cuticle synonym: "cuticle" RELATED [MA:0002704] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/9f/Fingernail_label.jpg/200px-Fingernail_label.jpg is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0001003 ! epidermis relationship: surrounds UBERON:0001705 ! nail xref: SCTID:24631007 ! Eponychium xref: http://upload.wikimedia.org/wikipedia/commons/9/9f/Fingernail_label.jpg [Term] id: UBERON:0011190 name: lunule of nail def: "A crescent-shaped whitish area of the bed of a fingernail or toenail. The lunula is the visible part of the nail matrix (i.e. the root of the nail)." [Wikipedia:unula_(anatomy)] synonym: "nail lunule" EXACT [FMA:77858] synonym: "lunula" EXACT [] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0001705 ! nail xref: FMA:77858 ! lunule of nail xref: SCTID:300538005 ! Entire lunula xref: ncithesaurus:Lunula ! lunula xref: UMLS:C0221991 [Term] id: UBERON:0008963 name: hoof def: "The tip of a toe of an ungulate mammal, strengthened by a thick horny (keratin) covering. The hoof consists of a hard or rubbery sole, and a hard wall formed by a thick nail rolled around the tip of the toe. The weight of the animal is normally borne by both the sole and the edge of the hoof wall. Hooves grow continuously, and are constantly worn down by use." [Wikipedia:Hoof] comment: The hoof is the integument of the foot. Like skin, the integument of the foot has three layers, namely the epidermis, dermis, and SC tissue. is_a: UBERON:0009564 ! distal limb integumentary appendage xref: BTO:0003994 ! hoof xref: SCTID:410026002 ! Entire hoof [Term] id: UBERON:0010759 name: equine distal sesamoid def: "lies on the palmar aspect of the coffin joint between the second phalanx and third phalanx. articulates closely with the distal phalanx, to which it is connected by the impar ligament of the navicular bone. The impar ligament is very strong and permits relatively little motion between the navicular bone and the distal phalanx." [Wikipedia:Equine_forelimb_anatomy#Distal_sesamoid, Wikipedia:Navicular_bone#Horse_anatomy] is_a: UBERON:0001479 ! sesamoid bone relationship: part_of UBERON:0002470 ! autopod region relationship: only_in_taxon NCBITaxon:9788 ! Equidae synonym: "navicular bone" RELATED INCONSISTENT [Wikipedia:Equine_forelimb_anatomy#Distal_sesamoid] xref: SCTID:370654009 ! Distal sesamoid of equine limb [Term] id: UBERON:0012334 name: navicular bursa def: "A fluid-filled sac that lies between the navicular bone and the deep digital flexor muscle" [http://medical-dictionary.thefreedictionary.com/navicular+bursa] synonym: "bursa podotrochlearis" EXACT [] is_a: UBERON:0003668 ! synovial bursa relationship: part_of UBERON:0002470 ! autopod region relationship: only_in_taxon NCBITaxon:9788 ! Equidae xref: SCTID:370660009 ! Navicular bursa of equine foot [Term] id: UBERON:0012335 name: navicular bursa of manus synonym: "bursa podotrochlearis manus" EXACT [http://medical-dictionary.thefreedictionary.com/bursa+podotrochlearis+manus] synonym: "navicular bursa of forelimb" EXACT [] intersection_of: UBERON:0012334 ! navicular bursa intersection_of: part_of UBERON:0002398 ! manus xref: SCTID:370736002 ! Navicular bursa of equine forefoot [Term] id: UBERON:0012343 name: navicular bursa of pes synonym: "bursa podotrochlearis pes" EXACT [] synonym: "navicular bursa of hindlimb" EXACT [] intersection_of: UBERON:0012334 ! navicular bursa intersection_of: part_of UBERON:0002387 ! pes [Term] id: UBERON:0012263 ! equine cannon bone name: equine cannon bone def: "The bone in a horse that is the equivalent of the 3rd metacarpal bone in other mammals." [http://en.wikipedia.org/wiki/Equine_forelimb_anatomy#Metacarpal_bones] is_a: UBERON:0003821 ! metapodium bone relationship: only_in_taxon NCBITaxon:9788 ! Equidae [Term] id: UBERON:0012264 name: equine forelimb cannon bone is_a: UBERON:0003647 ! metacarpal bone of digit 3 intersection_of: UBERON:0012263 ! equine cannon bone intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002398 {source="reference_0000032"} ! manus [Term] id: UBERON:0012265 name: equine hindlimb cannon bone is_a: UBERON:0003652 ! metatarsal bone of digit 3 intersection_of: UBERON:0012263 ! equine cannon bone intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002387 {source="reference_0000032"} ! pes [Term] id: UBERON:0012267 ! equine splint bone name: equine splint bone def: "The splint bones sit either side of the cannon bone. Homologous to metapodium bones 2 or 4" [] is_a: UBERON:0003821 ! metapodium bone relationship: adjacent_to UBERON:0012263 ! equine cannon bone relationship: only_in_taxon NCBITaxon:9788 ! Equidae [Term] id: UBERON:0012268 name: equine forelimb splint bone intersection_of: UBERON:0012267 ! equine splint bone intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002398 {source="reference_0000032"} ! manus [Term] id: UBERON:0012269 name: equine hindlimb splint bone intersection_of: UBERON:0012267 ! equine splint bone intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002387 {source="reference_0000032"} ! pes [Term] id: UBERON:0009554 name: coffin bone def: "the bottommost bone in the equine leg and is encased by the hoof capsule. The distal phalanx articulates with both the middle phalanx and the distal sesamoid, forming the distal interphalangeal joint " [Wikipedia:Coffin_bone] synonym: "pedal bone" EXACT [Wikipedia:Coffin_bone, Wikipedia:Equine_forelimb_anatomy#Distal_phalanx] synonym: "equine distal phalanx" EXACT [UBERON:cjm] is_a: UBERON:0004300 ! distal phalanx relationship: part_of UBERON:0006050 ! digit 3 relationship: only_in_taxon NCBITaxon:9788 ! Equidae [Term] id: UBERON:0009555 name: short pastern bone def: "." [Wikipedia:Equine_forelimb_anatomy#Middle_phalanx] synonym: "equine middle phalanx" EXACT [UBERON:cjm] is_a: UBERON:0004301 ! middle phalanx relationship: part_of UBERON:0009563 ! pastern region of limb [Term] id: UBERON:0009556 name: long pastern bone def: "." [Wikipedia:Equine_forelimb_anatomy#Proximal_phalanx] synonym: "equine proximal phalanx" EXACT [UBERON:cjm] is_a: UBERON:0004302 ! proximal phalanx relationship: part_of UBERON:0009563 ! pastern region of limb [Term] id: UBERON:0009557 name: coffin joint synonym: "equine distal interphalangeal joint" EXACT [UBERON:cjm] xref: SCTID:196392002 ! Coffin joint is_a: UBERON:0006658 ! inter-phalangeal joint relationship: part_of UBERON:0009563 ! pastern region of limb [Term] id: UBERON:0009558 ! pastern bone name: pastern bone def: "A bone that is part of the pastern region of a horse limb." [Wikipedia:Pastern] intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0009563 ! pastern region of limb xref: http://upload.wikimedia.org/wikipedia/commons/5/56/Equine-dist-forelimb-bones.png [Term] id: UBERON:0009563 ! pastern region of limb name: pastern region of limb def: "a part of the leg of a horse between the fetlock and the top of the hoof. It incorporates the long pastern bone (proximal phalanx) and the short pastern bone (middle phalanx), which are held together by two sets of paired ligaments to form the pastern joint (proximal interphalangeal joint)" [Wikipedia:Pastern] comment: note that digit is used very generically in uberon, to include the homologous region in ungulates. Taxon notes: Anatomically homologous to the two largest bones found in the human finger xref: SCTID:370725009 ! Pastern region of equine limb is_a: UBERON:0002529 ! limb segment relationship: part_of UBERON:0006050 ! digit 3 [Term] id: UBERON:0009551 ! distal segment of digit name: distal segment of digit def: "A segment of a digit containing the distal phalanx, and overlapping the interphalangeal joint[CJM]. The digit tip is derived from multiple and distinct embryonic origins, and includes the distal bone with associated marrow cavity and haematopoietic cells, ventral (flexor) and dorsal (extensor) tendons, sweat glands with myoepithelial and luminal secreting cells and associated neurons for innervation, dermis with resident melanocytes and dendritic cells, mesenchyme with resident fibroblasts, skin epidermis with hair follicles, a nail organ composed of six specific parts (the root, nail bed, nail plate, eponychium (cuticle), perionychium and hyponychium)." [doi:10.1038/nature10346] comment: Newborn and adult mice are able to regrow forelimb (finger) and hindlimb (toe) digit tips after their amputation through the distal interphalangeal joint. Regeneration of the digit tip involves the integrated regrowth of multiple tissues within 2–3 months, reaching an external morphology that is cosmetically and functionally similar to normal digits. Most importantly, regeneration of the mouse distal digit shares morphological similarities with clinical cases documenting regrowth of missing distal portions of fingers in both children and adults synonym: "digit tip" EXACT [UBERON:cjm] synonym: "tip of digit" EXACT [UBERON:cjm] synonym: "distal digit segment" EXACT [UBERON:cjm] is_a: UBERON:0002529 ! limb segment relationship: part_of UBERON:0002544 ! digit relationship: overlaps UBERON:0006658 {source="cjm"} ! inter-phalangeal joint [Term] id: UBERON:0009552 alt_id: UBERON:0004093 name: distal segment of manual digit def: "." [HP:0001211] xref: OpenCyc:Mx4rvVjpf5wpEbGdrcN5Y29ycA ! fingertip synonym: "tip of finger" EXACT [SCTID:312543003] synonym: "fingertip" EXACT [HP:0001211] synonym: "finger digit tip" EXACT [doi:10.1038/nature10346] synonym: "forelimb digit tip" EXACT [doi:10.1038/nature10346] synonym: "finger tip" EXACT [UBERON:cjm] synonym: "finger distal segment" EXACT [UBERON:cjm] comment: in SNOMED this is a surface region. Here we intend it to be the entire distal segment is_a: UBERON:0005451 ! segment of manus intersection_of: UBERON:0009551 ! distal segment of digit intersection_of: part_of UBERON:0002389 ! manual digit xref: SCTID:312543003 ! Tip of finger [Term] id: UBERON:0009553 name: distal segment of pedal digit synonym: "tip of toe" EXACT [UBERON:cjm] synonym: "toe distal segment" EXACT [UBERON:cjm] synonym: "toe digit tip" EXACT [doi:10.1038/nature10346] synonym: "hindlimb digit tip" EXACT [doi:10.1038/nature10346] is_a: UBERON:0005445 ! segment of pes intersection_of: UBERON:0009551 ! distal segment of digit intersection_of: part_of UBERON:0001466 ! pedal digit def: "A distal segment of digit that is part of a pedal digit." [OBOL:automatic] [Term] id: UBERON:0005275 ! dorsal skin of digit name: dorsal skin of digit synonym: "skin of dorsal part of digit" EXACT [] synonym: "dorsal digit skin" EXACT [] is_a: UBERON:0000014 ! zone of skin relationship: part_of UBERON:0002544 ! digit [Term] id: UBERON:0005276 name: dorsal skin of finger comment: this class is explicitly the union of the two FMA classes synonym: "skin of dorsal part of finger" EXACT [FMA:38320] synonym: "dorsal finger skin" EXACT [] synonym: "subdivision of skin of dorsal part of finger" EXACT [FMA:60346] xref: FMA:60346 ! Subdivision of skin of dorsal part of finger xref: FMA:38320 ! skin of dorsal part of finger intersection_of: UBERON:0005275 ! dorsal skin of digit intersection_of: part_of UBERON:0002389 ! manual digit def: "A dorsal skin of digit that is part of a manual digit." [OBOL:automatic] [Term] id: UBERON:0005277 name: dorsal skin of toe comment: this class is explicitly the union of the two FMA classes synonym: "skin of dorsal part of toe" EXACT [FMA:37868] synonym: "dorsal toe skin" EXACT [] synonym: "subdivision of skin of dorsal part of toe" EXACT [FMA:60523] xref: FMA:37868 ! skin of dorsal part of toe xref: FMA:60523 ! Subdivision of skin of dorsal part of toe intersection_of: UBERON:0005275 ! dorsal skin of digit intersection_of: part_of UBERON:0001466 ! pedal digit def: "A dorsal skin of digit that is part of a pedal digit." [OBOL:automatic] [Term] id: UBERON:0005308 name: nephrostome def: "The nephrostome is the opening of the pronephros into the body cavity[GO]." [GO:0039018] xref: XAO:0000062 ! nephrostome is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002120 ! pronephros xref: AAO:0011069 ! nephrostome [Term] id: UBERON:0005309 ! pronephric nephron name: pronephric nephron def: "A pronephric nephron is the functional unit of the pronephros[GO]." [GO:0039019] xref: XAO:0000285 ! pronephric nephron intersection_of: UBERON:0001285 ! nephron intersection_of: part_of UBERON:0002120 ! pronephros xref: AAO:0011091 ! pronephric nephron property_value: external_definition "The structure that is the basic functional unit of the pronephros.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0011091", date_retrieved="2012-06-20", source="UBERON:0005309"} [Term] id: UBERON:0006173 name: pronephric proximal tubule def: "A pronephric nephron tubule is an epithelial tube that is part of the pronephros" [GO:0039011] synonym: "pronephros proximal tubule" EXACT [GO:0039011] intersection_of: UBERON:0004134 ! proximal tubule intersection_of: part_of UBERON:0002120 ! pronephros relationship: part_of UBERON:0005309 {source="reference_0000032"} ! pronephric nephron [Term] id: UBERON:0005310 name: pronephric nephron tubule def: "The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]." [GO:0039020] synonym: "pronephric tubule" EXACT [ZFA:0001558] xref: ZFA:0001558 ! pronephric tubule is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0001231 ! nephron tubule intersection_of: part_of UBERON:0005309 ! pronephric nephron relationship: part_of UBERON:0005309 {source="GO"} ! pronephric nephron relationship: dubious_for_taxon NCBITaxon:32524 {source="ISBN10:0073040584"} ! Amniota xref: XAO:0004105 ! pronephric tubule xref: TAO:0001558 ! pronephric tubule property_value: external_definition "Bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts. In zebrafish and other teleosts, the pronephric nephron and tubules form after the pronephric duct, connecting to the anterior-most tip of the pronephric ducts. Drummond, 2000.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001558", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005312 name: primary ureteric bud def: "." [GO:0060682] is_a: UBERON:0000084 ! ureteric bud [Term] id: UBERON:0005313 name: mammary duct terminal end bud def: "." [GO:0060763] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001765 ! lactiferous duct [Term] id: UBERON:0005316 name: endocardial endothelium def: "The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]." [GO:0061147] synonym: "endocardium endothelium" EXACT [FMA:83596] is_a: UBERON:0001986 {source="FMA"} ! endothelium relationship: part_of UBERON:0002165 {source="FMA"} ! endocardium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002165 ! endocardium xref: FMA:83596 ! endothelium of endocardium synonym: "endothelium of endocardium" EXACT [FMA:83596] [Term] id: UBERON:0005317 name: pulmonary artery endothelium def: "An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]." [GO:0061155] synonym: "pulmonary artery endothelial tube" EXACT [GO:0061155] xref: BTO:0000137 ! pulmonary artery endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002012 ! pulmonary artery [Term] id: UBERON:0005319 name: mesonephric collecting duct def: "The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]." [GO:0061211] xref: XAO:0000151 ! mesonephric collecting duct intersection_of: UBERON:0001232 ! collecting duct of renal tubule intersection_of: part_of UBERON:0000080 ! mesonephros xref: AAO:0010390 ! mesonephric collecting duct relationship: part_of UBERON:0005322 {is_inferred="true", source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0005320 name: mesonephric juxtaglomerular apparatus def: "The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]." [GO:0061212] intersection_of: UBERON:0002303 ! juxtaglomerular apparatus intersection_of: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005321 name: mesonephric smooth muscle tissue def: "." [GO:0061214] intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005323 ! mesonephric mesenchyme name: mesonephric mesenchyme def: "Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros[GO]." [GO:0061219] xref: EMAPA:27585 ! mesonephric mesenchyme of mesonephros of genitourinary system xref: EMAPA:27661 ! mesonephric mesenchyme of mesonephros of reproductive system xref: XAO:0000291 ! mesonephric mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000080 ! mesonephros xref: AAO:0011062 ! mesonephric mesenchyme xref: EHDAA2:0001132 ! mesonephros mesenchyme [Term] id: UBERON:0005324 name: mesonephric macula densa def: "The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus[GO]." [GO:0061220] intersection_of: UBERON:0002335 ! macula densa intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005320 {is_inferred="true", source="reference_0000032"} ! mesonephric juxtaglomerular apparatus [Term] id: UBERON:0005325 name: mesonephric glomerulus def: "The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros[GO]." [GO:0061224] comment: AN notes: XAO/AAO class belongs here, as it refers to mesonephric structure xref: EMAPA:30568 ! mesonephric glomerulus of cranial mesonephric tubule of mesonephric tubule of mesonephros of genitourinary system xref: EMAPA:30580 ! mesonephric glomerulus of cranial mesonephric tubule of mesonephric tubule of mesonephros of reproductive system xref: VHOG:0001238 ! mesonephric glomerulus xref: AAO:0010388 ! glomerulus xref: XAO:0000146 ! glomerulus synonym: "glomerulus" BROAD SENSU [AAO:0010388] intersection_of: UBERON:0000074 ! renal glomerulus intersection_of: part_of UBERON:0000080 ! mesonephros property_value: external_definition "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010388", date_retrieved="2012-06-20", source="AAO:BJB"} xref: SCTID:362217000 ! Entire glomerulus (also: UBERON:0000074 'renal glomerulus') (also: UBERON:0005749 'glomerular tuft') property_value: homology_notes "In animals in which the mesonephros is the terminal kidney, such as amphibians and fish, the final organ is very complex, containing a large number of nephrons, most of which have an internal glomerulus.[well established][VHOG]" xsd:string {external_class="VHOG:0001238", ontology="VHOG", source="ISBN:978-0127224411 Vize PD\, Woolf AS\, Bard JBL\, The kidney: From normal development to congenital disease (2003) p.3", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005326 name: mesonephric glomerulus vasculature def: "The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus[GO]." [GO:0061231] intersection_of: UBERON:0004190 ! glomerulus vasculature intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005325 {is_inferred="true", source="reference_0000032"} ! mesonephric glomerulus [Term] id: UBERON:0005327 name: mesonephric glomerular epithelium def: "A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros[GO]." [GO:0061232] intersection_of: UBERON:0004188 ! glomerular epithelium intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005325 {is_inferred="true", source="reference_0000032"} ! mesonephric glomerulus relationship: part_of UBERON:0005322 {source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0005328 name: mesonephric comma-shaped body def: "The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]." [GO:0061236] intersection_of: UBERON:0004198 ! comma-shaped body intersection_of: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005329 name: mesonephric nephron tubule def: "A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros[GO]." [GO:0061240] synonym: "mesonephric renal tubule" EXACT [UBERON:cjm] is_a: UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005330 name: mesonephric nephron epithelium def: "The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]." [GO:0061241] intersection_of: UBERON:0004211 ! nephron epithelium intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005322 {is_inferred="true", source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0005332 name: mesonephric S-shaped body def: "The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]." [GO:0061244] intersection_of: UBERON:0004199 ! S-shaped body intersection_of: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005342 ! malleus head name: malleus head def: "rounded portion of the malleus that articulates with the body of the incus[MP]." [MP:0008379] synonym: "head of malleus" EXACT [FMA:52761] xref: FMA:52761 ! head of malleus xref: MA:0002987 ! malleus head is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001689 ! malleus xref: SCTID:368926004 ! Entire head of malleus [Term] id: UBERON:0005344 name: peritoneal vaginal process def: "A peritoneal diverticulum in the embryonic lower anterior abdominal wall that traverses the inguinal canal. In the male it forms the tunica vaginalis testis and normally loses its connection with the peritoneal cavity; a persistent processus vaginalis in the female is known as the canal of Nuck[MP]." [MP:0009218, Wikipedia:Processus_vaginalis] synonym: "processus vaginalis peritonei" RELATED PLURAL [MP:0009218] synonym: "processus vaginalis peritoneus" EXACT [MP:0009218] synonym: "vaginal process of peritoneum" EXACT [MP:0009218] synonym: "vaginal process of testis" RELATED [MP:0009218] synonym: "peritoneal diverticulum" RELATED [] synonym: "vaginal process of the peritoneum" RELATED [] synonym: "vaginal process of peritoneum" RELATED [] synonym: "saccus vaginalis" EXACT [Wikipedia:Processus_vaginalis] synonym: "vaginal process" RELATED [Wikipedia:Processus_vaginalis] synonym: "processus vaginalis peritonei" RELATED LATIN [Wikipedia:Processus_vaginalis] synonym: "processus vaginalis peritonei masculinus" NARROW LATIN [Wikipedia:Processus_vaginalis] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Mesorchium.svg/200px-Mesorchium.svg.png is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0002358 ! peritoneum xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Mesorchium.svg xref: SCTID:362726001 ! Entire processus vaginalis peritonei [Term] id: UBERON:0005347 name: copula pyramidis def: ".[MP]." [MP:0010000] xref: ABA:COPY ! Copula pyramidis is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0004003 ! cerebellum hemisphere lobule relationship: spatially_disjoint_from UBERON:0005348 {source="ABA"} ! ansiform lobule relationship: spatially_disjoint_from UBERON:0001063 {source="ABA"} ! flocculus relationship: spatially_disjoint_from UBERON:0005351 {source="ABA"} ! paraflocculus relationship: spatially_disjoint_from UBERON:0005349 {source="ABA"} ! paramedian lobule relationship: spatially_disjoint_from UBERON:0005350 {source="ABA"} ! lobule simplex [Term] id: UBERON:0005348 ! ansiform lobule name: ansiform lobule def: ".[MP]." [MP:0010001] synonym: "ansiform lobule of cerebellum" EXACT [FMA:72257] synonym: "ansiform lobule of cerebellum [h vii a]" EXACT [FMA:72257] synonym: "semilunar lobules of cerebellum" EXACT [FMA:72257] xref: FMA:72257 ! ansiform lobule of cerebellum xref: ABA:AN ! Ansiform lobule is_a: UBERON:0004003 ! cerebellum hemisphere lobule relationship: spatially_disjoint_from UBERON:0005347 {source="ABA"} ! copula pyramidis relationship: spatially_disjoint_from UBERON:0001063 {source="ABA"} ! flocculus relationship: spatially_disjoint_from UBERON:0005351 {source="ABA"} ! paraflocculus relationship: spatially_disjoint_from UBERON:0005349 {source="ABA"} ! paramedian lobule relationship: spatially_disjoint_from UBERON:0005350 {source="ABA"} ! lobule simplex synonym: "lobuli semilunares cerebelli" EXACT LATIN [FMA:TA, FMA:72257] synonym: "lobulus ansiformis cerebelli [h vii a]" EXACT LATIN [FMA:TA, FMA:72257] [Term] id: UBERON:0005349 name: paramedian lobule def: ".[MP]." [MP:0010004] synonym: "gracile lobule" EXACT [FMA:72523] synonym: "paramedian lobule [H VII B]" EXACT [FMA:72523] synonym: "hemispheric lobule VIIBii" EXACT [NIF_GrossAnatomy:nlx_anat_20081210] synonym: "lobulus gracilis" EXACT [NIF_GrossAnatomy:nlx_anat_20081210] synonym: "lobulus paramedianus" EXACT [NIF_GrossAnatomy:nlx_anat_20081210] synonym: "paramedian 1 (hvii)" EXACT [NIF_GrossAnatomy:nlx_anat_20081210] xref: FMA:72523 ! gracile lobule xref: NIF_GrossAnatomy:nlx_anat_20081210 ! Hemispheric Lobule VIIBii xref: ABA:PRM ! Paramedian lobule is_a: UBERON:0004003 ! cerebellum hemisphere lobule relationship: spatially_disjoint_from UBERON:0005348 {source="ABA"} ! ansiform lobule relationship: spatially_disjoint_from UBERON:0005347 {source="ABA"} ! copula pyramidis relationship: spatially_disjoint_from UBERON:0001063 {source="ABA"} ! flocculus relationship: spatially_disjoint_from UBERON:0005351 {source="ABA"} ! paraflocculus relationship: spatially_disjoint_from UBERON:0005350 {source="ABA"} ! lobule simplex synonym: "lobulus paramedianus [h vii b]" EXACT LATIN [FMA:TA, FMA:72523] [Term] id: UBERON:0005350 name: lobule simplex def: ".[MP]." [MP:0010005] synonym: "hemispheric lobule VI" EXACT [NIF_GrossAnatomy:nlx_anat_20081206] synonym: "simple lobule of cerebellum" EXACT [FMA:72522] synonym: "simple lobule" EXACT [MP:0010005] synonym: "lobule h vi of larsell" EXACT [FMA:72522] synonym: "posterior crescentic lobule of cerebellum" EXACT [FMA:72522] synonym: "semilunar lobule-1 (posterior)" EXACT [FMA:72522] synonym: "simple lobule of cerebellum [h vi and vi]" EXACT [FMA:72522] synonym: "lobulus quadrangularis posterior" EXACT [NIF_GrossAnatomy:nlx_anat_20081206] synonym: "lobulus simplex" EXACT [NIF_GrossAnatomy:nlx_anat_20081206] synonym: "simplex (hvi)" EXACT [NIF_GrossAnatomy:nlx_anat_20081206] synonym: "simplex lobule" EXACT [NIF_GrossAnatomy:nlx_anat_20081206] xref: FMA:72522 ! simple lobule of cerebellum xref: NIF_GrossAnatomy:nlx_anat_20081206 ! Hemispheric Lobule VI xref: ABA:SIM ! Simple lobule is_a: UBERON:0004003 ! cerebellum hemisphere lobule relationship: spatially_disjoint_from UBERON:0005348 {source="ABA"} ! ansiform lobule relationship: spatially_disjoint_from UBERON:0005347 {source="ABA"} ! copula pyramidis relationship: spatially_disjoint_from UBERON:0001063 {source="ABA"} ! flocculus relationship: spatially_disjoint_from UBERON:0005351 {source="ABA"} ! paraflocculus relationship: spatially_disjoint_from UBERON:0005349 {source="ABA"} ! paramedian lobule synonym: "lobulus simplex cerebelli [h vi et vi]" EXACT LATIN [FMA:TA, FMA:72522] [Term] id: UBERON:0005351 name: paraflocculus def: ".[MP]." [MP:0010007] synonym: "hemispheric lobule IX" EXACT [NIF_GrossAnatomy:nlx_anat_20081212] synonym: "paraflocculus of cerebellum " EXACT [FMA:83885] synonym: "paraflocculus of cerebellum" EXACT [FMA:83885] synonym: "neuraxis paraflocculus" EXACT [FMA:83885] synonym: "cerebellar tonsil" EXACT [NIF_GrossAnatomy:nlx_anat_20081212] synonym: "tonsil (HXI)" EXACT [NIF_GrossAnatomy:nlx_anat_20081212] synonym: "tonsilla" EXACT [NIF_GrossAnatomy:nlx_anat_20081212] xref: FMA:83885 ! paraflocculus of cerebellum xref: NIF_GrossAnatomy:nlx_anat_20081212 ! Hemispheric Lobule IX xref: ABA:PFL ! Paraflocculus is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002245 ! hemisphere of cerebellum relationship: spatially_disjoint_from UBERON:0005348 {source="ABA"} ! ansiform lobule relationship: spatially_disjoint_from UBERON:0005347 {source="ABA"} ! copula pyramidis relationship: spatially_disjoint_from UBERON:0001063 {source="ABA"} ! flocculus relationship: spatially_disjoint_from UBERON:0005349 {source="ABA"} ! paramedian lobule relationship: spatially_disjoint_from UBERON:0005350 {source="ABA"} ! lobule simplex disjoint_from: UBERON:0002372 ! tonsil xref: SCTID:314174005 ! Entire cerebellar tonsil xref: SCTID:51969002 ! Paraflocculus [Term] id: UBERON:0005352 ! spermatic cord name: spermatic cord def: "The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]." [MP:0010145, Wikipedia:Spermatic_cord] synonym: "funiculus spermaticus" RELATED LATIN [Wikipedia:Spermatic_cord] synonym: "spermatic chord" RELATED [] xref: FMA:19937 ! spermatic cord xref: GAID:395 xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/35/Male_anatomy.png/200px-Male_anatomy.png xref: MESH:A05.360.444.777 ! spermatic cord is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0004054 ! internal male genitalia xref: ncithesaurus:Spermatic_Cord ! Spermatic Cord xref: SCTID:181433005 ! Entire spermatic cord xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png xref: UMLS:C0037855 [Term] id: UBERON:0005354 name: malleus processus brevis def: "the projection extending from the base of the manubrium of the malleus which contacts the upper part of the tympanic membrane where the tympanic cavity makes a deep pocket (epitympanic pocket) surrounding the cartilaginous nodule[MP]." [MP:0010324] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0001689 ! malleus [Term] id: UBERON:0005355 ! malleus neck name: malleus neck def: "the narrow contracted section of the malleus located between the head and the manubrium[MP]." [MP:0010327, Wikipedia:Neck_of_malleus] synonym: "neck of malleus" EXACT [FMA:52762] xref: FMA:52762 ! neck of malleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/6b/Gray916.png/200px-Gray916.png xref: MA:0002988 ! malleus neck is_a: UBERON:0001560 ! neck of organ relationship: part_of UBERON:0001689 ! malleus xref: SCTID:368927008 ! Entire neck of malleus synonym: "collum mallei" RELATED LATIN [Wikipedia:Neck_of_malleus] xref: http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray916.png [Term] id: UBERON:0005403 name: ventral striatum def: "The ventral striatum is a portion of the striatum. It consists of the nucleus accumbens and the olfactory tubercle. Some sources also include the ventromedial parts of the caudate nucleus and putamen. It is considered a reward center." [Wikipedia:Ventral_striatum] xref: FMA:77614 ! Ventral striatum xref: MA:0002972 ! ventral striatum xref: BTO:0004702 ! ventral striatum xref: EFO:0001936 ! ventral striatum xref: ABA:STRv ! Striatum ventral region is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002435 ! striatum [Term] id: UBERON:0005405 name: pararenal fat def: "The paranephric body (or paranephric fat or pararenal fat) is collection of adipose tissue located superficial to the renal fascia. The perirenal fat, or adipose capsule of kidney, is deep to the renal fascia but superficial to the renal capsule." [Wikipedia:Paranephric_body] comment: TODO - split paranephric / pararenal synonym: "paranephric body" RELATED [Wikipedia:Paranephric_body] synonym: "paranephric fat" RELATED [MA:0002974] synonym: "pararenal fascia" RELATED [MA:0002974] synonym: "pararenal fat body" RELATED [MA:0002974] synonym: "pararenal fascia" EXACT [FMA:20503] xref: FMA:20503 ! Pararenal fat xref: FMA:74280 ! Paranephric fat xref: MA:0002974 ! pararenal fat is_a: UBERON:0001013 ! adipose tissue synonym: "corpus adiposum pararenale" RELATED LATIN [Wikipedia:Paranephric_body] xref: http://upload.wikimedia.org/wikipedia/commons/c/c1/Gray1125.png [Term] id: UBERON:0005406 name: perirenal fat def: "The adipose capsule of kidney (or perinephric fat or perirenal fat) is a structure between the renal fascia and renal capsule, and may be regarded as a part of the latter. A different structure, the pararenal fat, is the adipose tissue superficial to the renal fascia." [Wikipedia:Adipose_capsule_of_kidney] comment: TODO - split perinephric / perirenal synonym: "adipose capsule of kidney" RELATED [MA:0002975] synonym: "fatty capsule of kidney" RELATED [MA:0002975] synonym: "perinephric fat" RELATED [MA:0002975] synonym: "periphrenic fascia" RELATED [MA:0002975] synonym: "perirenal fascia" RELATED [MA:0002975] synonym: "perirenal fat capsule" RELATED ATTRIBUTION_REQUIRED [MA:0002975] synonym: "perirenal fascia" EXACT [FMA:20502] xref: FMA:20502 ! Perirenal fat xref: FMA:15876 ! Perirenal fat capsule xref: MA:0002975 ! perirenal fat is_a: UBERON:0001013 ! adipose tissue xref: SCTID:246901006 ! Entire perirenal fat synonym: "capsula adiposa renis" RELATED LATIN [Wikipedia:Adipose_capsule_of_kidney] xref: http://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg [Term] id: UBERON:0005408 ! circumventricular organ name: circumventricular organ def: "Brain region located around or in relation to the ventricular system that is highly vascularized and distinguished by the lack of a blood brain barrier." [NIF_GrossAnatomy:nlx_anat_20090312, Wikipedia:Circumventricular_organs] comment: AO notes: MA subdivides into sensory and secretory synonym: "CVO" EXACT [NIF_GrossAnatomy:nlx_anat_20090312] synonym: "circumventricular organ" EXACT [NIF_GrossAnatomy:nlx_anat_20090312] xref: MA:0002942 ! circumventricular organ xref: NIF_GrossAnatomy:nlx_anat_20090312 ! Circumventricular organ xref: FMA:84081 ! Circumventricular organ of neuraxis is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000955 ! brain xref: http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray734.png synonym: "circumventricular organ of neuraxis" EXACT [FMA:84081] [Term] id: UBERON:0010134 name: secretory circumventricular organ is_a: UBERON:0010133 {source="MA"} ! neuroendocrine gland is_a: UBERON:0005408 {source="MA"} ! circumventricular organ xref: MA:0002943 ! secretory circumventricular organ [Term] id: UBERON:0010135 name: sensory circumventricular organ is_a: UBERON:0005408 {source="MA"} ! circumventricular organ relationship: part_of UBERON:0001032 ! sensory system xref: MA:0002944 ! sensory circumventricular organ [Term] id: UBERON:0005430 name: ansa cervicalis def: "The ansa cervicalis (or ansa hypoglossi in older literature) is a loop of nerves that are part of the cervical plexus. It lies superficial to the internal jugular vein in the carotid sheath. Branches from the ansa cervicalis innervate three of the four infrahyoid muscles, including the sternohyoid muscle, the sternothyroid muscle, and the omohyoid muscle." [Wikipedia:Ansa_cervicalis] synonym: "ansa hypoglossi" RELATED [Wikipedia:Ansa_cervicalis] xref: FMA:55142 ! Ansa cervicalis xref: EHDAA2:0000124 ! ansa cervicalis xref: EHDAA:6669 ! ansa cervicalis is_a: UBERON:0001147 ! trunk of peripheral nerve xref: SCTID:362474000 ! Entire ansa cervicalis xref: http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray795.png [Term] id: UBERON:0002458 name: spinal artery def: "Arteries that supply the spinal cord." [UBERON:cjm, Wikipedia:Spinal_artery] subset: uberon_slim subset: vertebrate_core synonym: "spinal arteries" EXACT PLURAL [ZFA:0000682] xref: EHDAA:4355 ! spinal artery xref: MA:0002043 ! spinal artery xref: ZFA:0000682 ! spinal artery xref: ncithesaurus:Spinal_Artery ! Spinal Artery xref: EHDAA2:0001890 ! spinal artery xref: EMAPA:18241 ! spinal artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002240 ! spinal cord xref: SCTID:244228006 ! Spinal artery xref: TAO:0000682 ! spinal artery xref: UMLS:C0447043 [Term] id: UBERON:0005431 name: anterior spinal artery def: "In human anatomy, the anterior spinal artery is the blood vessel that supplies the anterior portion of the spinal cord. It arises from branches of the vertebral arteries and is supplied by the anterior segmental medullary arteries, including the artery of Adamkiewicz, and courses along the anterior aspect of the spinal cord." [Wikipedia:Anterior_spinal_artery] synonym: "anterior spinal arteries" RELATED [Wikipedia:Anterior_spinal_artery] synonym: "arteria spinalis anterior" RELATED [Wikipedia:Anterior_spinal_artery] synonym: "ventral artery of the spinal cord" RELATED [Wikipedia:Anterior_spinal_artery] synonym: "anterior medial spinal artery" EXACT [FMA:50531] synonym: "ventral spinal artery" EXACT [FMA:50531] xref: FMA:50531 ! Anterior spinal artery xref: EHDAA2:0000131 ! anterior spinal artery xref: EMAPA:18242 ! anterior of spinal artery xref: EHDAA:6382 ! anterior spinal artery is_a: UBERON:0002458 ! spinal artery relationship: part_of UBERON:0004571 ! systemic arterial system relationship: branch_of UBERON:0001535 ! vertebral artery relationship: supplies UBERON:0002240 ! spinal cord relationship: develops_from UBERON:0005599 {source="EHDAA2"} ! common dorsal aorta xref: ncithesaurus:Anterior_Spinal_Artery ! Anterior Spinal Artery xref: SCTID:181329004 ! Entire anterior spinal artery synonym: "arteria spinalis anterior" RELATED LATIN [Wikipedia:Anterior_spinal_artery] xref: http://upload.wikimedia.org/wikipedia/commons/7/73/Anterior_spinal_cord_-_very_low_mag.jpg xref: UMLS:C0149603 [Term] id: UBERON:0007146 name: posterior spinal artery def: "The posterior spinal artery (dorsal spinal artery) arises from the vertebral artery, adjacent to the medulla oblongata." [Wikipedia:Posterior_spinal_artery] synonym: "dorsal spinal artery" EXACT [FMA:50522] xref: FMA:50522 ! Posterior spinal artery xref: EMAPA:18243 ! posterior spinal artery is_a: UBERON:0002458 ! spinal artery relationship: develops_from UBERON:0001535 {source="EHDAA2"} ! vertebral artery xref: ncithesaurus:Posterior_Spinal_Artery ! Posterior Spinal Artery xref: SCTID:181330009 ! Entire posterior spinal artery xref: UMLS:C0226233 [Term] id: UBERON:0005432 name: aortic sac def: "the merged ventral aortae of the embryo which supplies blood to the aortic arches[TMD]." [http://medical-dictionary.thefreedictionary.com/aortic+sac] xref: FMA:71008 ! Aortic sac xref: RETIRED_EHDAA2:0000133 ! aortic sac xref: EHDAA:9826 ! aortic sac is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0001637 {source="EHDAA2"} ! artery relationship: develops_from UBERON:0004363 {source="EHDAA2"} ! aortic arch relationship: part_of UBERON:0004145 ! outflow tract xref: SCTID:361527005 ! Aortic sac xref: EHDAA2:0004145 ! aortic sac [Term] id: UBERON:0005433 name: autonomic peripheral nervous system comment: TODO - check ANS, PNS synonym: "autonomic division of peripheral nervous system" EXACT [FMA:65553] synonym: "autonomic part of peripheral nervous system" EXACT [FMA:65553] synonym: "peripheral autonomic nervous system" EXACT [FMA:65553] synonym: "peripheral part of autonomic nervous system" EXACT [FMA:65553] xref: FMA:65553 ! Peripheral part of autonomic nervous system xref: EHDAA2:0000158 ! autonomic peripheral nervous system xref: EMAPA:16984 ! autonomic (also: UBERON:0002410 'autonomic nervous system') xref: MESH:A08.800.050 ! autonomic nervous system (also: UBERON:0002410 'autonomic nervous system') xref: EHDAA:3767 ! autonomic (also: UBERON:0002410 'autonomic nervous system') is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0002410 ! autonomic nervous system synonym: "pars autonomica systematis nervosi peripherici" EXACT LATIN [FMA:TA, FMA:65553] synonym: "divisio autonomica systematis nervosi peripherici" EXACT LATIN [FMA:TA, FMA:65553] xref: SCTID:429921001 ! Structure of peripheral part of autonomic nervous system [Term] id: UBERON:0005435 name: cisterna chyli def: "The cisterna chyli (or cysterna chyli, and etymologically more correct, receptaculum chyli) is a dilated sac at the lower end of the thoracic duct into which lymph from the intestinal trunk and two lumbar lymphatic trunks flow." [Wikipedia:Cisterna_chyli] synonym: "chyle cistern" RELATED [Wikipedia:Cisterna_chyli] synonym: "cysterna chyli" RELATED [Wikipedia:Cisterna_chyli] synonym: "Atypical confluence of lymph trunks" EXACT [FMA:5835] synonym: "Chyle cistern" EXACT [FMA:5835] synonym: "Cistern of Pecquet" EXACT [FMA:5835] xref: FMA:5835 ! Cisterna chyli xref: EHDAA2:0000253 ! cisterna chyli xref: EHDAA:8679 ! cisterna chyli is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0002465 ! lymphoid system relationship: part_of UBERON:0001631 ! thoracic duct xref: ncithesaurus:Chyle_Cistern ! Chyle Cistern xref: SCTID:279088007 ! Entire cisterna chyli xref: http://upload.wikimedia.org/wikipedia/commons/7/75/Gray599.png xref: UMLS:C0008840 [Term] id: UBERON:0005436 name: common hepatic artery def: "In anatomy, the common hepatic artery is a short blood vessel that supplies oxygenated blood to the liver, pylorus (a part of the stomach), duodenum (a part of the small intestine) and pancreas. It arises from the celiac artery and has the following branches:" [Wikipedia:Common_hepatic_artery] synonym: "common hepatic" RELATED [Wikipedia:Common_hepatic_artery] xref: FMA:14771 ! Common hepatic artery xref: EHDAA2:0000308 ! common hepatic artery xref: EHDAA:8570 ! common hepatic artery is_a: UBERON:0004573 ! systemic artery relationship: branch_of UBERON:0001640 ! celiac artery xref: galen:CommonHepaticArtery xref: SCTID:244263001 ! Entire common hepatic artery synonym: "arteria hepatica communis" RELATED LATIN [Wikipedia:Common_hepatic_artery] xref: http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png [Term] id: UBERON:0005437 name: conus medullaris def: "The conus medullaris is the terminal end of the spinal cord. It occurs near lumbar vertebral levels 1 (L1) and 2 (L2). After the spinal cord tapers out, the spinal nerves continue as dangling nerve roots called cauda equina. This terminal nerve root tail is referred to as the filum terminale. The upper end of the conus medullaris is usually not well defined." [Wikipedia:Conus_medullaris] synonym: "medullary cone" EXACT [] synonym: "termination of the spinal cord" RELATED [] xref: FMA:74897 ! Conus medullaris xref: EHDAA2:0000315 ! conus medullaris xref: EMAPA:18219 ! conus medullaris xref: VHOG:0000546 ! conus medullaris xref: EHDAA:6684 ! conus medullaris is_a: UBERON:0005844 ! spinal cord segment xref: ncithesaurus:Conus_Medullaris ! Conus Medullaris xref: SCTID:315472009 ! Entire conus medullaris xref: http://upload.wikimedia.org/wikipedia/commons/f/f4/Gray662.png property_value: external_definition "The conical end of the spinal cord, which continues with the filum terminale. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000546", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0149601 [Term] id: UBERON:0005438 name: coronary sinus def: "The coronary sinus is a collection of veins joined together to form a large vessel that collects blood from the myocardium of the heart. It is present in humans and other animals. The coronary sinus opens into the right atrium, between the inferior vena cava and the auriculo-ventricular opening. It returns the blood from the substance of the heart, and is protected by a semicircular fold of the lining membrane of the auricle, the coronary valve. (valve of Thebesius). The sinus, before entering the auricle, is considerably dilated - nearly to the size of the end of the little finger. Its wall is partly muscular, and at its junction with the great coronary vein is somewhat constricted and furnished with a valve consisting of two unequal segments. - Gray 462" [Wikipedia:Coronary_sinus] synonym: "sinus coronarius" EXACT [] xref: FMA:4706 ! Coronary sinus xref: EHDAA2:0000320 ! coronary sinus xref: EHDAA:9884 ! coronary sinus is_a: UBERON:0003920 ! venous blood vessel relationship: part_of UBERON:0004581 ! systemic venous system relationship: part_of UBERON:0000948 ! heart xref: ncithesaurus:Coronary_Sinus ! Coronary Sinus xref: SCTID:244386006 ! Entire coronary sinus synonym: "sinus coronarius" RELATED LATIN [Wikipedia:Coronary_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray491.png xref: UMLS:C0456944 [Term] id: UBERON:0005439 name: definitive endoderm synonym: "Embryonic endoderm" EXACT [FMA:85519] xref: FMA:85519 ! Definitive endoderm xref: EHDAA2:0000337 ! definitive endoderm xref: EMAPA:16070 ! definitive endoderm xref: VHOG:0000751 ! definitive endoderm xref: EHDAA:218 ! definitive endoderm xref: EFO:0002574 ! definitive endoderm is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000925 ! endoderm [Term] id: UBERON:0005440 ! ductus arteriosus name: ductus arteriosus def: "A fetal blood vessel connecting the pulmonary artery with the descending aorta[MESH]. In the developing fetus, the ductus arteriosus is a shunt connecting the pulmonary artery to the aortic arch. It allows most of the blood from the right ventricle to bypass the fetus' fluid-filled lungs, protecting the lungs from being overworked and allowing the left ventricle to strengthen. There are two other fetal shunts, the ductus venosus and the foramen ovale[MP]. the fetal vessel that connects the left pulmonary artery with the descending aorta; the ductus arteriosus normally regresses into a fibrous cord, the ligamentum arteriousum after birth[MP]" [Wikipedia:Ductus_arteriosus, MP:0010564, MESH:A07.541.278.395] synonym: "fetal ductus arteriosus" RELATED [MP:0010564] synonym: "Botallo's duct" RELATED [Wikipedia:Ductus_arteriosus] synonym: "ductus arteriosis" RELATED [Wikipedia:Ductus_arteriosus] synonym: "ductus arteriosum" RELATED [Wikipedia:Ductus_arteriosus] synonym: "ductus botalli" RELATED [Wikipedia:Ductus_arteriosus] synonym: "ductus layton" RELATED [Wikipedia:Ductus_arteriosus] synonym: "arterial canal" RELATED [MP:0010564] synonym: "arterial duct" RELATED [MP:0010564] synonym: "ductus Botallo" EXACT [MP:0010564] xref: FMA:79871 ! Ductus arteriosus xref: EHDAA2:0000420 ! ductus arteriosus xref: EMAPA:17858 ! ductus arteriosus xref: MESH:A07.541.278.395 ! ductus arteriosus xref: VHOG:0000923 ! ductus arteriosus xref: EHDAA:6462 ! ductus arteriosus of outflow tract of heart xref: EFO:0002515 ! ductus arteriosus xref: MA:0001947 ! ductus arteriosis is_a: UBERON:0001637 {source="MA"} ! artery relationship: part_of UBERON:0004571 ! systemic arterial system relationship: part_of UBERON:0004145 {source="EHDAA2"} ! outflow tract relationship: part_of UBERON:0011695 ! embryonic cardiovascular system relationship: continuous_with UBERON:0003123 ! aortic arch 6 relationship: continuous_with UBERON:0002012 ! pulmonary artery relationship: develops_from UBERON:0003123 {source="Wikipedia"} ! aortic arch 6 xref: ncithesaurus:Ductus_Arteriosus ! Ductus Arteriosus xref: galen:DuctusArteriosus xref: SCTID:253684002 ! Entire ductus arteriosus xref: http://upload.wikimedia.org/wikipedia/commons/e/ee/Gray502.png property_value: external_definition "The temporary channel or blood vessel between the aorta and pulmonary artery in the fetus. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000923", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/ductus+arteriosus", source="http://bgee.unil.ch/"} property_value: homology_notes "On the other hand, in the sister clade of the actinopterygians, the sarcopterygians, the gill circulation is supplemented with lung ventilation. As a result, the pulmonary artery and vein and a functional ductus arteriosus arose as a major evolutionary innovation from the sixth arch, giving the organism a flexible shunt to balance blood supply to and from gills and lungs according to environmental conditions.[well established][VHOG]" xsd:string {external_class="VHOG:0000923", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0013273 [Term] id: UBERON:0007642 ! ligamentum arteriosum name: ligamentum arteriosum def: "a small ligament attached to the superior surface of the pulmonary trunk and the inferior surface of the aortic arch. It is a nonfunctional vestige of the ductus arteriosus, and is formed within three weeks of birth. The ligamentum arteriosum is closely related to the left recurrent laryngeal nerve, a branch of the left vagus nerve. After splitting from the left vagus nerve, the left recurrent laryngeal loops around the aortic arch posterior to the ligamentum arteriosum, after which it ascends to the larynx[WP]." [Wikipedia:Ligamentum_arteriosum] synonym: "Botallo's duct" EXACT [FMA:13421] synonym: "Botallo's ligament" EXACT [FMA:13421] synonym: "Harvey's ligament" EXACT [FMA:13421] synonym: "arterial ligament" RELATED [Wikipedia:Ligamentum_arteriosum] xref: FMA:13421 ! ligamentum arteriosum is_a: UBERON:0006591 {source="FMA"} ! transformed artery intersection_of: UBERON:0006591 ! transformed artery intersection_of: develops_from UBERON:0005440 ! ductus arteriosus xref: SCTID:198009004 ! Entire ligamentum arteriosum [Term] id: UBERON:0007643 name: node of ligamentum arteriosum def: "an inconstant lymph node of the anterior mediastinal group located adjacent to the ligamentum arteriosum." [http://www.mondofacto.com/facts/dictionary?node+of+ligamentum+arteriosum] synonym: "Botallo's node" EXACT [FMA:74033] synonym: "ligamentum arteriosum node" EXACT [FMA:74033] synonym: "lymph node of ligamentum arteriosum" EXACT [UBERON:cjm] synonym: "nodus ligamenti arteriosi" EXACT [http://www.mondofacto.com/facts/dictionary?node+of+ligamentum+arteriosum] xref: FMA:74033 ! node of ligamentum arteriosum is_a: UBERON:0002524 {source="FMA"} ! mediastinal lymph node relationship: adjacent_to UBERON:0007642 ! ligamentum arteriosum [Term] id: UBERON:0005441 name: external intercostal muscle def: "The Intercostales externi (External intercostals) are eleven in number on either side. They extend from the tubercles of the ribs behind, to the cartilages of the ribs in front, where they end in thin membranes, the anterior intercostal membranes, which are continued forward to the sternum. Each arises from the lower border of a rib, and is inserted into the upper border of the rib below. In the two lower spaces they extend to the ends of the cartilages, and in the upper two or three spaces they do not quite reach the ends of the ribs. They are thicker than the Intercostales interni, and their fibers are directed obliquely downward and laterally on the back of the thorax, and downward, forward, and medially on the front (the example is often used of sticking one's hands in their pocket and noting the direction of the fingers pointing downward and medially)." [Wikipedia:External_intercostal_muscles] synonym: "external intercostal muscle" RELATED [Wikipedia:External_intercostal_muscles] synonym: "external intercostals" RELATED [Wikipedia:External_intercostal_muscles] synonym: "intercostales externi" RELATED [Wikipedia:External_intercostal_muscles] synonym: "intercostales externi muscle" RELATED [Wikipedia:External_intercostal_muscles] synonym: "intercostales externi muscles" RELATED [Wikipedia:External_intercostal_muscles] synonym: "intercostalis externus" RELATED [Wikipedia:External_intercostal_muscles] synonym: "intercostals external" RELATED [Wikipedia:External_intercostal_muscles] synonym: "intercostals external muscle" RELATED [Wikipedia:External_intercostal_muscles] synonym: "musculi intercostales externi" RELATED [Wikipedia:External_intercostal_muscles] synonym: "intercostales externus" EXACT [MA:0002325] synonym: "intercostal muscle external layer" RELATED [MA:0002325] synonym: "musculi intercostales externi" RELATED LATIN [Wikipedia:External_intercostal_muscles] xref: FMA:9756 ! External intercostal muscle xref: EHDAA2:0000465 ! external intercostal muscle xref: EHDAA:8260 ! external of intercostal xref: MA:0002325 ! intercostales externus is_a: UBERON:0001111 {source="FMA"} ! intercostal muscle relationship: develops_from UBERON:0010974 {source="EHDAA2"} ! external intercostal pre-muscle mass relationship: innervated_by UBERON:0003727 {source="dbpedia"} ! intercostal nerve disjoint_from: UBERON:0003831 {source="PMID:15755883"} ! respiratory system muscle xref: ncithesaurus:External_Intercostal_Muscle ! External Intercostal Muscle xref: SCTID:244878003 ! Entire external intercostal muscle xref: http://upload.wikimedia.org/wikipedia/commons/f/f2/Gray411.png xref: VHOG:0000904 ! intercostales externus property_value: homology_notes "Behind the thorax, the lateral group (of muscles in reptiles and mammals) remains essentially as for amphibians. (It breaks into three sheet-like layers: external oblique muscle, the internal oblique, and the transversus). More anteriorly, however, the ribs, now enlarged, penetrate and alter this group of muscles. The transversus is excluded from the thorax and the external and internal obliques become, respectively, the external and internal intercostal muscles, which contribute to the new function of ventilation of the lungs.[well established][VHOG]" xsd:string {external_class="VHOG:0000904", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.193", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1744535 [Term] id: UBERON:0010974 name: external intercostal pre-muscle mass is_a: UBERON:0010970 {source="EHDAA2"} ! intercostal pre-muscle mass xref: EHDAA2:0000467 ! external intercostal pre-muscle mass [Term] id: UBERON:0012100 name: appendicocostalis muscle def: "." [PMID:15755883] synonym: "appendicocostalis" EXACT [PMID:15755883] is_a: UBERON:0003831 ! respiratory system muscle [Term] id: UBERON:0005442 ! external oblique name: external oblique def: "The external oblique muscle (of the abdomen) (also external abdominal oblique muscle) is the largest and the most superficial (outermost) of the three flat muscles of the lateral anterior abdomen." [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external abdominal oblique" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external abdominal oblique muscle" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external oblique" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external oblique abdominal muscles" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external oblique abdominis" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external oblique abdominis muscle" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external oblique muscle" EXACT [Wikipedia:Abdominal_external_oblique_muscle] synonym: "oblique strength" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "obliquus abdominis externus" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "obliquus externus" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "obliquus externus abdominis" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "obliquus externus abdominis muscle" RELATED [Wikipedia:Abdominal_external_oblique_muscle] synonym: "external abdominal oblique muscle" EXACT [FMA:13335] synonym: "obliquus externus abdominis" EXACT [MA:0002345] xref: FMA:13335 ! External oblique xref: EHDAA2:0000469 ! external oblique xref: MA:0002345 ! obliquus externus abdominis xref: EMAPA:18162 ! external oblique xref: VHOG:0000788 ! abdominal external oblique muscle xref: EHDAA:8248 ! external oblique is_a: UBERON:0002461 {source="FMA"} ! anterior abdominal wall muscle relationship: develops_from UBERON:0010975 {source="EHDAA2"} ! external oblique pre-muscle mass relationship: has_muscle_origin UBERON:0002228 ! rib relationship: has_muscle_insertion UBERON:0006204 {source="dbpedia"} ! inguinal ligament relationship: innervated_by UBERON:0003727 {source="dbpedia", notes="lower 6 intercostal nerve + subcostal nerve"} ! intercostal nerve xref: ncithesaurus:External_Oblique_Muscle ! External Oblique Muscle xref: SCTID:244946005 ! External oblique subset: organ_slim synonym: "m. obliquus externus abdominis" RELATED LATIN [Wikipedia:Abdominal_external_oblique_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/3/32/Illu_trunk_muscles.jpg synonym: "abdominal external oblique muscle" EXACT [VHOG:0000788] property_value: homology_notes "Behind the thorax, the lateral group (of muscles in reptiles and mammals) remains essentially as for amphibians. (It breaks into three sheet-like layers: external oblique muscle, the internal oblique, and the transversus). More anteriorly, however, the ribs, now enlarged, penetrate and alter this group of muscles. The transversus is excluded from the thorax and the external and internal obliques become, respectively, the external and internal intercostal muscles, which contribute to the new function of ventilation of the lungs.[well established][VHOG]" xsd:string {external_class="VHOG:0000788", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.193", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0224375 [Term] id: UBERON:0010975 name: external oblique pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme relationship: part_of UBERON:0002461 {source="EHDAA2"} ! anterior abdominal wall muscle xref: EHDAA2:0000470 ! external oblique pre-muscle mass [Term] id: UBERON:0005443 name: filum terminale def: "The filum terminale (\"terminal thread\"), is a delicate strand of fibrous tissue, about 20 cm. in length, proceeding downward from the apex of the conus medullaris. It gives longitudinal support to the spinal cord and consists of two parts: The upper part, or filum terminale internum, is about 15 cm. long and reaches as far as the lower border of the second sacral vertebra. It is continuous above with the pia mater and contained within a tubular sheath of the dura mater. In addition, it is surrounded by the nerves forming the cauda equina, from which it can be easily recognized by its bluish-white color. The lower part, or filum terminale externum, closely adheres to the dura mater. It extends downward from the apex of the tubular sheath and is attached to the back of the first segment of the coccyx in a structure sometimes referred to as the coccygeal ligament. The most inferior of the spinal nerves, the coccygeal nerve leaves the spinal cord at the level of the conus medullaris, superior to the filum terminale. However, adhering to the outer surface of the filum terminale are a few strands of nerve fibers which probably represent rudimentary second and third coccygeal nerves. Furthermore, the central canal of the spinal cord extends 5 to 6 cm. beyond the conus medullaris, downward into the filum terminale." [Wikipedia:Filum_terminale] synonym: "coccygeal ligament" RELATED [] synonym: "filum terminale segment of pia mater" EXACT [FMA:83977] synonym: "terminal filum" EXACT [FMA:83977] synonym: "pars pialis fili terminalis" EXACT LATIN [FMA:TA, FMA:83977] xref: FMA:83977 ! Filum terminale xref: EHDAA2:0000510 ! filum terminale xref: EMAPA:18220 ! filum terminale xref: VHOG:0000547 ! filum terminale xref: EHDAA:6686 ! filum terminale is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0002240 ! spinal cord xref: SCTID:361344005 ! Entire filum terminale xref: http://upload.wikimedia.org/wikipedia/commons/f/f4/Gray662.png property_value: external_definition "The slender, thread-like continuation of the spinal cord below the origin of the lumbar nerves. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000547", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0010269 name: filum terminale internum is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0005443 {source="FMA"} ! filum terminale xref: FMA:256524 ! internal part of filum terminale synonym: "internal part of filum terminale" EXACT [FMA:256524] xref: SCTID:315673007 ! Entire filum terminale internum [Term] id: UBERON:0010270 name: filum terminale externum is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0005443 {source="FMA"} ! filum terminale xref: FMA:256526 ! external part of filum terminale synonym: "external part of filum terminale" EXACT [FMA:256526] xref: SCTID:315573001 ! Entire filum terminale externum [Term] id: UBERON:0012337 name: cauda equina def: "The cauda equina is a structure within the lower end of the spinal column of most vertebrates, that consists of nerve roots and rootlets from above. The space in which the cerebrospinal fluid is present is actually an extension of the subarachnoid space. In humans, because the spinal cord stops growing in infancy while the bones of the spine continue growing, the spinal cord in adults ends at about the level of the vertebra L1/L2, and at birth at L3. However there is some variation in adults and the cord may end anywhere between vertebrae T12 to L3. Individual spinal nerve roots arise from the spinal cord as they do closer to the head, but as the differential growth occurs the top end of the nerve stays attached to the spinal cord and the lower end of the nerve exits the spinal column at its proper level, this results in a \"bundle\"-like structure of nerve fibres that extends caudally from the end of the spinal cord, gradually declining in number further down as individual pairs leave the spinal column. At the base of the Cauda Equina, there are approximately 10 fiber pairs, 3-5 lumbar, 5 sacral, and the single coccygeal nerve." [Wikipedia:Cauda_equina] synonym: "filum terminale" RELATED [MESH:A08.800.800.720.725.150] is_a: UBERON:0005162 ! multi cell component structure relationship: part_of UBERON:0009623 {source="MESH"} ! spinal nerve root xref: MESH:A08.800.800.720.725.150 ! cauda equina xref: FMA:52590 ! cauda equina xref: SCTID:263377004 ! Entire cauda equina xref: ncithesaurus:Cauda_Equina ! cauda equina xref: UMLS:C0007458 [Term] id: UBERON:0005444 name: obsolete first polar body comment: belongs in CL synonym: "polocytus primarius" EXACT [FMA:18650] consider: FMA:18650 ! First polar body consider: EHDAA2:0000541 ! first polar body is_obsolete: true [Term] id: UBERON:0012139 ! segment of autopod name: segment of autopod is_a: UBERON:0002529 {notes="may be revised"} ! limb segment relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0005445 name: segment of pes synonym: "foot region" BROAD [FMA:24993] synonym: "foot subdivision" EXACT [FMA:24993] synonym: "subdivision of foot" EXACT [FMA:24993] synonym: "segment of foot" EXACT [FMA:24993] synonym: "regio pedis" EXACT LATIN [FMA:TA, FMA:24993] xref: FMA:24993 ! Segment of foot intersection_of: UBERON:0012139 ! segment of autopod intersection_of: part_of UBERON:0002387 ! pes xref: SCTID:362887000 ! Region of foot def: "A segment of autopod that is part of a pes." [OBOL:automatic] [Term] id: UBERON:0005451 name: segment of manus synonym: "hand region" BROAD [FMA:24945] synonym: "hand subdivision" EXACT [FMA:24945] synonym: "subdivision of hand" EXACT [FMA:24945] synonym: "segment of hand" EXACT [FMA:24945] synonym: "regio manus" EXACT LATIN [] xref: FMA:24945 ! Segment of hand intersection_of: UBERON:0012139 ! segment of autopod intersection_of: part_of UBERON:0002398 ! manus xref: SCTID:127950000 ! Region of hand def: "A segment of autopod that is part of a manus." [OBOL:automatic] [Term] id: UBERON:0012140 ! digitopodium region name: digitopodium region def: "A segment of the autopod consisting of both acropodial region and metapodial region, but excluding the mesopodial/basopodial region." [PHENOSCAPE:ni] comment: Terminology notes: some sources call this the acropodium. see http://purl.obolibrary.org/obo/uberon/references/reference_0000019 synonym: "autopod proper" RELATED [] synonym: "acropodium (Wagner)" RELATED [] is_a: UBERON:0012139 ! segment of autopod relationship: adjacent_to UBERON:0006716 ! mesopodium region property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000019" xsd:anyURI [Term] id: UBERON:0012141 name: manual digitopodium region def: "A digitopodium region that is part of a manus[Obol]. This includes the fingers and metacarpal region, but excludes the carpal region." [] comment: Terminology notes: some sources call this the acropodium. see http://purl.obolibrary.org/obo/uberon/references/reference_0000019 intersection_of: UBERON:0012140 ! digitopodium region intersection_of: part_of UBERON:0002398 ! manus synonym: "hand proper" RELATED [FMA:61067] xref: FMA:61067 ! hand proper property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000019" xsd:anyURI [Term] id: UBERON:0012142 name: pedal digitopodium region def: "A digitopodium region that is part of a pes[Obol]. This includes the toes and metatarsal region, but excludes the tarsals region." [] comment: Terminology notes: some sources call this the acropodium. see http://purl.obolibrary.org/obo/uberon/references/reference_0000019 intersection_of: UBERON:0012140 ! digitopodium region intersection_of: part_of UBERON:0002387 ! pes synonym: "foot proper" RELATED [FMA:73084] xref: FMA:73084 ! foot proper property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000019" xsd:anyURI [Term] id: UBERON:0012150 ! skeleton of digitopodium name: skeleton of digitopodium def: "A subdivision of the autopod skeleton consisting of both acropodial skeleon and metapodial skeleton, but excluding the mesopodial/basopodial skeleton." [PHENOSCAPE:ni] comment: Terminology notes: some sources call this the acropodium. see http://purl.obolibrary.org/obo/uberon/references/reference_0000019 synonym: "digitopodium" RELATED [PHENOSCAPE:ni] synonym: "autopod proper skeleton" RELATED [] intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: subdivision_of UBERON:0012140 ! digitopodium region relationship: part_of UBERON:0012140 ! digitopodium region relationship: part_of UBERON:0006717 ! autopodial skeleton property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000019" xsd:anyURI [Term] id: UBERON:0012151 name: skeleton of manual digitopodium def: "A subdivision of the manus skeleton consisting of both manual acropodial skeleton and metacarpal skeleton, but excluding the carpal skeleton." [PHENOSCAPE:ni, UBERON:cjm] comment: Terminology notes: some sources call this the acropodium. see http://purl.obolibrary.org/obo/uberon/references/reference_0000019 synonym: "manual digitopodium" RELATED [] synonym: "hand proper skeleton" RELATED [FMA:79180] synonym: "skeleton of hand proper" RELATED [FMA:79180] intersection_of: UBERON:0012150 ! skeleton of digitopodium intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0012141 {source="FMA"} ! manual digitopodium region relationship: part_of UBERON:0001442 ! skeleton of manus xref: FMA:79180 ! skeleton of hand proper property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000019" xsd:anyURI [Term] id: UBERON:0012152 name: skeleton of pedal digitopodium def: "A subdivision of the pes skeleton consisting of both pedal acropodial skeleton and metatarsal skeleton, but excluding the tarsal skeleton." [PHENOSCAPE:ni, UBERON:cjm] comment: Terminology notes: some sources call this the acropodium. see http://purl.obolibrary.org/obo/uberon/references/reference_0000019 synonym: "pedal digitopodium" RELATED [] synonym: "foot proper skeleton" RELATED [] synonym: "skeleton of foot proper" RELATED [] intersection_of: UBERON:0012150 ! skeleton of digitopodium intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0012142 ! pedal digitopodium region relationship: part_of UBERON:0001445 ! skeleton of pes property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000019" xsd:anyURI [Term] id: UBERON:0005446 name: foramen rotundum def: "The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa." [Wikipedia:Foramen_rotundum] comment: AAO to be checked synonym: "foramen rotundum of the skull" RELATED [Wikipedia:Foramen_rotundum] xref: FMA:53154 ! Foramen rotundum xref: EHDAA2:0000552 ! foramen rotundum xref: EMAPA:18712 ! foramen rotundum xref: AAO:0000194 ! foramen perilymphaticum superius xref: EHDAA:10629 ! foramen rotundum is_a: UBERON:0005744 ! cranial conduit relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium relationship: surrounded_by UBERON:0001677 ! sphenoid bone xref: SCTID:369439002 ! Entire foramen rotundum synonym: "foramen rotundum ossis sphenoidalis" RELATED LATIN [Wikipedia:Foramen_rotundum] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Gray145.png xref: VHOG:0001543 ! foramen rotundum synonym: "round foramen" RELATED [VHOG:0001543] property_value: external_definition "A circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa.vity. [http://en.wikipedia.org/wiki/Foramen_rotundum][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001543", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "It is suggested that the mammalian lamina ascendens arose from an upgrowth of the root of the quadrate ramus of the epipterygoid in cynodonts, separating foramen rotundum from foramen ovale.[well established][VHOG]" xsd:string {external_class="VHOG:0001543", ontology="VHOG", source="PMID:1018003 Presley R\, Steel FLD\, On the homology of the alisphenoid. Journal of Anatomy (1976)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005447 name: obsolete bladder fundus is_obsolete: true consider: UBERON:0006081 consider: UBERON:0006082 [Term] id: UBERON:0006081 name: fundus of gallbladder def: "The fundus of gallbladder is the portion of the gallbladder which lies the farthest from the cystic duct. It is covered with peritoneum. A traditional cholecystectomy is most commonly performed from the infundibulum to the fundus. It's at the same level as the transpyloric plane." [Wikipedia:Fundus_of_gallbladder] synonym: "fundus of the gallbladder" RELATED [Wikipedia:Fundus_of_gallbladder] synonym: "gallbladder fundus" RELATED [Wikipedia:Fundus_of_gallbladder] synonym: "gallbladder fundus" EXACT [FMA:14536] xref: FMA:14536 ! fundus of gallbladder is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002110 ! gallbladder xref: ncithesaurus:Gallbladder_Fundus ! Gallbladder Fundus xref: SCTID:245391004 ! Entire fundus of gallbladder synonym: "fundus vesicae biliaris" RELATED LATIN [Wikipedia:Fundus_of_gallbladder] xref: http://upload.wikimedia.org/wikipedia/commons/4/44/Gray1095_parts.png xref: UMLS:C0227544 [Term] id: UBERON:0006082 name: fundus of urinary bladder def: "The base or posterior surface of the urinary bladder contains the trigone of the bladder and the outlet where urine empties through the internal urethral orifice." [Wikipedia:Fundus_of_the_urinary_bladder#Fundus, MP:0011785] synonym: "urinary bladder base" EXACT [MP:0011785] synonym: "base of urinary bladder" EXACT [FMA:15908] synonym: "fundus of bladder" BROAD [FMA:15908] synonym: "urinary bladder fundus" EXACT [FMA:15908] synonym: "urinary bladder fundus region" EXACT [MA:0001694] synonym: "fundus vesicae" EXACT LATIN [FMA:TA, FMA:15908] xref: FMA:15908 ! fundus of urinary bladder xref: EHDAA:9330 ! fundus xref: EHDAA2:0000582 ! bladder fundus xref: VHOG:0001184 ! urinary bladder fundus region xref: MA:0001694 ! urinary bladder fundus region xref: EMAPA:18322 ! fundus region is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001255 ! urinary bladder relationship: develops_from UBERON:0005760 {source="EHDAA2-modified"} ! urorectal septum relationship: develops_from UBERON:0009845 {source="EHDAA2"} ! urogenital sinus mesenchyme xref: ncithesaurus:Bladder_Fundus ! Bladder Fundus xref: SCTID:362226002 ! Entire fundus of urinary bladder xref: UMLS:C0447584 [Term] id: UBERON:0012442 name: epiploic foramen def: "In human anatomy, the omental foramen, is the passage of communication, or foramen, between the general cavity (of the abdomen), and the omental bursa." [Wikipedia:Omental_foramen] synonym: "bristle in epiploic foramen" RELATED [Wikipedia:Omental_foramen] synonym: "epiploic foramen" RELATED [Wikipedia:Omental_foramen] synonym: "epiploic foramen of Winslow" RELATED [Wikipedia:Omental_foramen] synonym: "foramen epiploicum" RELATED [Wikipedia:Omental_foramen] synonym: "foramen of winslow" RELATED [Wikipedia:Omental_foramen] synonym: "aditus to lesser sac" EXACT [FMA:14711] synonym: "foramen of Winslow" EXACT [FMA:14711] synonym: "foramen omentale" EXACT [FMA:TA] synonym: "foramen omentale (epiploicum)" EXACT [FMA:14711] synonym: "omental foramen" EXACT [FMA:14711] is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0001179 ! peritoneal cavity xref: FMA:14711 ! epiploic foramen xref: SCTID:264473006 ! Entire epiploic foramen xref: EHDAA2:0000447 ! epiploic foramen of Winslow [Term] id: UBERON:0005448 name: greater omentum def: "The greater omentum (also the great omentum, omentum majus, gastrocolic omentum, epiploön, or, especially in animals, caul) is a large fold of peritoneum that hangs down from the stomach, and extends from the stomach to the posterior abdominal wall after associating with the transverse colon." [Wikipedia:Greater_omentum] synonym: "caul" RELATED [Wikipedia:Greater_omentum] synonym: "epiploic" RELATED [Wikipedia:Greater_omentum] synonym: "epiplooen" RELATED [Wikipedia:Greater_omentum] synonym: "epiploön" RELATED [Wikipedia:Greater_omentum] synonym: "epiploon" RELATED [Wikipedia:Greater_omentum] synonym: "gastrocolic omentum" RELATED [Wikipedia:Greater_omentum] synonym: "great omentum" RELATED [Wikipedia:Greater_omentum] synonym: "omentectomy" RELATED [Wikipedia:Greater_omentum] synonym: "omentum majus" RELATED [Wikipedia:Greater_omentum] xref: FMA:9580 ! Greater omentum xref: EHDAA2:0000720 ! greater omentum xref: EMAPA:18660 ! greater omentum of dorsal mesogastrium of mesentery of stomach of foregut xref: EMAPA:18904 ! greater omentum of dorsal mesogastrium of mesentery of stomach of gut xref: VHOG:0000356 ! greater omentum xref: EHDAA:6071 ! greater omentum xref: EV:0100085 ! greater omentum is_a: UBERON:0003688 ! omentum relationship: develops_from UBERON:0005602 {source="Wikipedia"} ! dorsal mesogastrium relationship: attaches_to UBERON:0001164 ! greater curvature of stomach relationship: part_of UBERON:0001178 {source="FMA"} ! visceral peritoneum relationship: located_in UBERON:0003887 {source="OG"} ! intraembryonic coelom relationship: develops_from UBERON:0002296 {source="Wikipedia"} ! dorsal mesentery xref: ncithesaurus:Greater_Omentum ! Greater Omentum xref: SCTID:362711003 ! Entire greater omentum synonym: "omentum majus" RELATED LATIN [Wikipedia:Greater_omentum] xref: http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray1035.png property_value: external_definition "A filmy, transparent double fold of the peritoneum, draping the transverse colon and coils of the small intestine. It is attached along the greater curvature of the stomach and the first part of the duodenum. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000356", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/greater+omentum", source="http://bgee.unil.ch/"} xref: UMLS:C0230259 [Term] id: UBERON:0005449 ! greater sac name: greater sac synonym: "peritoneum of the peritoneal cavity proper" RELATED [Wikipedia:Greater_sac] synonym: "general cavity of the abdomen" RELATED [Wikipedia:Greater_sac] synonym: "peritoneal cavity greater sac" EXACT [MA:0000448] xref: FMA:19799 ! Greater sac xref: EHDAA2_RETIRED:0000722 ! greater sac xref: EMAPA:16885 ! greater sac of peritoneal component xref: EMAPA:18453 ! greater sac of peritoneal cavity xref: VHOG:0000858 ! greater sac xref: MA:0000448 ! peritoneal cavity greater sac xref: EHDAA:2327 ! greater sac xref: EHDAA2:0004738 ! greater sac is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0002358 ! peritoneum relationship: located_in UBERON:0001179 ! peritoneal cavity xref: http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray1035.png [Term] id: UBERON:0005450 name: greater sac cavity def: "the cavity in the abdomen that is inside the peritoneum but outside of the lesser sac. [WP,unvetted]." [Wikipedia:Greater_sac] synonym: "cavum peritonei" EXACT [FMA:9691] synonym: "greater peritoneal cavity" EXACT [FMA:9691] synonym: "cavity of greater sac" EXACT [FMA:9691] synonym: "greater sac lumen" EXACT [EHDAA2:0000724] xref: FMA:9691 ! Cavity of greater sac xref: EHDAA2:0000724 ! greater sac lumen xref: EMAPA:16886 ! cavity of greater sac of peritoneal component xref: EMAPA:18454 ! cavity of greater sac of peritoneal cavity (also: UBERON:0001179 'peritoneal cavity') xref: VHOG:0000528 ! greater sac cavity intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0005449 ! greater sac relationship: part_of UBERON:0005449 ! greater sac relationship: develops_in UBERON:0001179 {source="EHDAA2"} ! peritoneal cavity [Term] id: UBERON:0005452 name: hepatic lamina def: "Composed of hepatocytes, usually only one cell thick. The spaces between hepatic plates are occupied by sinusoids." [ISBN:0387949542] synonym: "hepatic plate" RELATED INCONSISTENT [FMA:14655] synonym: "hepatic cord" EXACT [FMA:14655] synonym: "lamina hepatica" EXACT [FMA:14655] synonym: "liver cell plate" EXACT [FMA:14655] synonym: "hepatic lamina" EXACT [FMA:14655] xref: FMA:14655 ! Hepatic lamina is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0004647 ! liver lobule relationship: part_of UBERON:0001172 ! hepatic acinus relationship: has_part CL:0000182 {source="FMA"} ! hepatocyte [Term] id: UBERON:0005453 name: inferior mesenteric ganglion def: "a ganglion located near where the inferior mesenteric artery branches from the abdominal aorta[WP]." [Wikipedia:Inferior_mesenteric_ganglion] xref: FMA:77590 ! Inferior mesenteric ganglion xref: EHDAA2:0000818 ! inferior mesenteric ganglion xref: EHDAA:8948 ! inferior mesenteric ganglion is_a: UBERON:0003964 ! prevertebral ganglion xref: SCTID:279277007 ! Entire inferior mesenteric ganglion synonym: "ganglion mesentericum inferius" RELATED LATIN [Wikipedia:Inferior_mesenteric_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/6/63/Gray848.png [Term] id: UBERON:0005454 name: internal oblique def: "The internal oblique muscle (of the abdomen) is the intermediate muscle of the abdomen, lying just underneath the external oblique and just above (superficial to) the transverse abdominal muscle." [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "abdominal internal oblique" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "internal abdominal oblique" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "internal abdominal oblique muscle" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "internal oblique abdominal" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "internal oblique abdominis" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "internal oblique abdominis muscle" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "internal oblique muscle" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "musculus obliquus internus abdominis" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "obliqui internus" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "obliquus internus" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "obliquus internus abdominis" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "obliquus internus abdominis muscle" RELATED [Wikipedia:Abdominal_internal_oblique_muscle] synonym: "obliquus internus abdominis muscle" EXACT [FMA:13891] synonym: "obliquus internus abdominis" EXACT [MA:0002346] xref: FMA:13891 ! Internal oblique xref: EHDAA2:0000879 ! internal oblique xref: MA:0002346 ! obliquus internus abdominis xref: EMAPA:18163 ! internal oblique xref: VHOG:0000789 ! abdominal internal oblique muscle xref: EHDAA:8250 ! internal oblique is_a: UBERON:0002461 ! anterior abdominal wall muscle xref: ncithesaurus:Internal_Oblique_Muscle ! Internal Oblique Muscle xref: SCTID:244947001 ! Internal oblique subset: organ_slim synonym: "Obliquus internus abdominis" RELATED LATIN [Wikipedia:Abdominal_internal_oblique_muscle] relationship: has_muscle_insertion UBERON:0002207 {source="dbpedia", notes="Linea alba Xiphoid process and the inferior ribs."} ! xiphoid process relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="Linea alba Xiphoid process and the inferior ribs."} ! rib relationship: has_muscle_origin UBERON:0006204 {source="dbpedia", notes="Inguinal ligament Iliac crest and the Lumbodorsal fascia."} ! inguinal ligament xref: http://upload.wikimedia.org/wikipedia/commons/3/32/Illu_trunk_muscles.jpg synonym: "abdominal internal oblique muscle" EXACT [VHOG:0000789] property_value: homology_notes "Behind the thorax, the lateral group (of muscles in reptiles and mammals) remains essentially as for amphibians. (It breaks into three sheet-like layers: external oblique muscle, the internal oblique, and the transversus). More anteriorly, however, the ribs, now enlarged, penetrate and alter this group of muscles. The transversus is excluded from the thorax and the external and internal obliques become, respectively, the external and internal intercostal muscles, which contribute to the new function of ventilation of the lungs.[well established][VHOG]" xsd:string {external_class="VHOG:0000789", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.193", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1512878 [Term] id: UBERON:0005455 name: interventricular groove synonym: "interventricular sulcus" EXACT [FMA:7223] xref: FMA:7223 ! Interventricular sulcus xref: RETIRED_EHDAA2:0000884 ! interventricular groove xref: VHOG:0000790 ! interventricular groove xref: EHDAA:1918 ! interventricular groove xref: EMAPA:17336 ! interventricular groove is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0006846 {source="EHDAA2"} ! groove relationship: part_of UBERON:0002082 ! cardiac ventricle xref: SCTID:277708006 ! Interventricular groove [Term] id: UBERON:0005489 name: anterior interventricular sulcus def: "The ventricles of the heart are separated by two grooves, one of which, the anterior longitudinal sulcus (or anterior interventricular sulcus), is situated on the sternocostal surface of the heart, close to its left margin. The other groove separating the ventricles is the posterior interventricular sulcus." [Wikipedia:Anterior_interventricular_sulcus] synonym: "anterior interventricular groove" RELATED [Wikipedia:Anterior_interventricular_sulcus] synonym: "anterior longitudinal sulcus" RELATED [Wikipedia:Anterior_interventricular_sulcus] synonym: "anterior interventricular groove" EXACT [FMA:7177] xref: FMA:7177 ! Anterior interventricular sulcus is_a: UBERON:0005455 {source="FMA"} ! interventricular groove xref: SCTID:277710008 ! Entire anterior interventricular sulcus synonym: "sulcus interventricularis anterior" RELATED LATIN [Wikipedia:Anterior_interventricular_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/4/46/Gray492.png [Term] id: UBERON:0005490 name: posterior interventricular sulcus def: "The ventricles are separated by two grooves, one of which, the anterior longitudinal sulcus, is situated on the sternocostal surface of the heart, close to its left margin, the other posterior longitudinal sulcus (posterior interventricular sulcus, inferior interventricular groove), on the diaphragmatic surface near the right margin. In it run the posterior interventricular artery and middle cardiac vein." [Wikipedia:Posterior_interventricular_sulcus] synonym: "posterior interventricular groove" RELATED [Wikipedia:Posterior_interventricular_sulcus] synonym: "posterior longitudinal sulci" RELATED [Wikipedia:Posterior_interventricular_sulcus] synonym: "posterior longitudinal sulcus" RELATED [Wikipedia:Posterior_interventricular_sulcus] synonym: "diaphragmatic interventricular groove" EXACT [FMA:7178] synonym: "inferior interventricular groove" EXACT [FMA:7178] synonym: "posterior interventricular groove" EXACT [FMA:7178] xref: FMA:7178 ! Posterior interventricular sulcus is_a: UBERON:0005455 {source="FMA"} ! interventricular groove xref: SCTID:277711007 ! Entire posterior interventricular sulcus synonym: "sulcus interventricularis anterior" RELATED LATIN [Wikipedia:Posterior_interventricular_sulcus] xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray491.png [Term] id: UBERON:0005456 name: jugular foramen def: "The jugular foramen is a large aperture in the base of the skull. It is located behind the carotid canal and is formed in front by the petrous portion of the temporal, and behind by the occipital; it is generally larger on the right than on the left side" [Wikipedia:Jugular_foramen] synonym: "foramen jugulare" RELATED [Wikipedia:Jugular_foramen] synonym: "Posterior lacerate foramen" EXACT [FMA:56432] xref: FMA:56432 ! Jugular foramen xref: EHDAA2:0000893 ! jugular foramen xref: AAO:0000249 ! jugular foramen xref: EMAPA:18713 ! jugular foramen xref: VHOG:0001113 ! jugular foramen xref: EHDAA:10631 ! jugular foramen is_a: UBERON:0005744 ! cranial conduit relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium xref: ncithesaurus:Jugular_Foramen ! Jugular Foramen xref: SCTID:361735006 ! Entire jugular foramen xref: http://upload.wikimedia.org/wikipedia/commons/f/fa/Foramenjugulare.PNG property_value: external_definition "Large foramen that houses the glossopharyngeal and vagus nerves and is located inside the condyloid fossa.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000249", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass braincase and otic capsule opening (AAO:0000051)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000249", date_retrieved="2012-06-20"} property_value: external_definition "One of a pair of openings between the lateral part of the occipital bone and the petrous part of the temporal bones in the skull. The foramen contains the inferior petrosal sinus; the transverse sinus; some meningeal branches of the occipital and ascending pharyngeal arteries; and the glossopharyngeal, vagus, and accessory nerves. [Free_Online_Medical_Dictionary]" xsd:string {ontology="VHOG", external_class="VHOG:0001113", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/jugular+foramen", source="http://bgee.unil.ch/"} xref: UMLS:C0222712 [Term] id: UBERON:0005483 ! thymus lobe name: thymus lobe synonym: "lobe of thymus" EXACT [FMA:71193] xref: FMA:71193 ! Lobe of thymus xref: RETIRED_EHDAA2:0002021 ! thymus lobe is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002046 ! thyroid gland relationship: in_lateral_side_of UBERON:0002370 {source="FMA-abduced-lr"} ! thymus [Term] id: UBERON:0005457 name: left thymus lobe synonym: "left thymic lobe" EXACT [FMA:71195] synonym: "left lobe of thymus" EXACT [FMA:71195] xref: FMA:71195 ! Left lobe of thymus xref: RETIRED_EHDAA2:0000964 ! left thymus lobe intersection_of: UBERON:0005483 ! thymus lobe intersection_of: in_left_side_of UBERON:0002370 ! thymus xref: SCTID:188079002 ! Entire left lobe of thymus def: "A thymus lobe that is in the left side of a thymus." [OBOL:automatic] [Term] id: UBERON:0005469 name: right thymus lobe synonym: "right thymic lobe" EXACT [FMA:71194] synonym: "right lobe of thymus" EXACT [FMA:71194] xref: FMA:71194 ! Right lobe of thymus xref: RETIRED_EHDAA2:0001758 ! right thymus lobe intersection_of: UBERON:0005483 ! thymus lobe intersection_of: in_right_side_of UBERON:0002370 ! thymus xref: SCTID:187981000 ! Entire right lobe of thymus def: "A thymus lobe that is in the right side of a thymus." [OBOL:automatic] [Term] id: UBERON:0011944 name: subintestinal vein subset: dubious_grouping synonym: "SIV" EXACT [ZFA:0005035] synonym: "vitelline vein" RELATED INCONSISTENT [ZFA:0005035] is_a: UBERON:0001638 {source="XAO"} ! vein xref: XAO:0004172 ! subintestinal vein xref: TAO:0005035 ! subintestinal vein (also: UBERON:0005487 'vitelline vein') xref: ZFA:0005035 ! subintestinal vein (also: UBERON:0005487 'vitelline vein') [Term] id: UBERON:0005487 ! vitelline vein name: vitelline vein def: "One of two veins which drain blood from the yolk sac. They run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids." [Wikipedia:Vitelline_veins] comment: AO notes: check zfa (no text def). Check vitelline/omphalomesenteric distinction in XAO subset: vertebrate_core synonym: "omphalomesenteric vein" RELATED [EMAPA:16244] synonym: "vein of omphalomesenteric system" RELATED [] synonym: "vena vitellina" EXACT LATIN [Wikipedia:Vitelline_veins] xref: FMA:70305 ! Vitelline vein xref: RETIRED_EHDAA2:0002209 ! vitelline vein xref: ZFA:0005035 ! subintestinal vein (also: UBERON:0011944 'subintestinal vein') xref: EMAPA:16244 ! vitelline vein of venous system of cardiovascular system of organ system xref: EMAPA:16379 ! vitelline vein of venous system of cardiovascular system of extraembryonic component xref: EMAPA:26151 ! vitelline vein of vitelline duct xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray475.png is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0004581 ! systemic venous system xref: ncithesaurus:Vitelline_Vein ! Vitelline Vein xref: XAO:0004147 ! vitelline vein xref: XAO:0000376 ! omphalomesenteric vein xref: TAO:0005035 ! subintestinal vein (also: UBERON:0011944 'subintestinal vein') xref: SCTID:308832003 ! Entire omphalomesenteric vein xref: SCTID:2730004 ! Entire vitelline vein of placenta xref: VHOG:0000401 ! embryonic vitelline vein synonym: "embryonic vitelline vein" EXACT [VHOG:0000401] property_value: homology_notes "Within each vertebrate group, the veins compose a few main functional systems that arise embryologically from what seems to be a common developmental pattern. (...) Early in development, three major sets of paired veins are present: the vitelline veins from the yolk sac, the cardinal veins from the body of the embryo itself, and the lateral abdominal veins from the pelvic region. The paired vitelline veins are among the first vessels to appear in the embryo. They arise over the yolk and follow the yolk stalk into the body. They then turn anteriorly, continue along the gut, and enter the sinus venosus.[well established][VHOG]" xsd:string {external_class="VHOG:0000401", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.460", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} property_value: external_definition "One of two veins that run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids.[XAO]" xsd:string {ontology="XAO", source="XAO:0004147"} xref: UMLS:C0231091 [Term] id: UBERON:0005460 name: left vitelline vein xref: FMA:70307 ! Left vitelline vein xref: EHDAA2:0000971 ! left vitelline vein xref: EMAPA:16698 ! left of vitelline vein of venous system of cardiovascular system of organ system xref: EMAPA:16380 ! left of vitelline vein of venous system of cardiovascular system of extraembryonic component intersection_of: UBERON:0005487 ! vitelline vein intersection_of: in_left_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:361446008 ! Left vitelline vein def: "A vitelline vein that is in the left side of a multi-cellular organism." [OBOL:automatic] [Term] id: UBERON:0005472 name: right vitelline vein xref: FMA:70306 ! Right vitelline vein xref: EHDAA2:0001766 ! right vitelline vein xref: EMAPA:16699 ! right of vitelline vein of venous system of cardiovascular system of organ system xref: EMAPA:16381 ! right of vitelline vein of venous system of cardiovascular system of extraembryonic component intersection_of: UBERON:0005487 ! vitelline vein intersection_of: in_right_side_of UBERON:0000468 ! multi-cellular organism xref: SCTID:361445007 ! Right vitelline vein def: "A vitelline vein that is in the right side of a multi-cellular organism." [OBOL:automatic] [Term] id: UBERON:0005461 name: levator scapulae muscle def: "The levator scapulae is situated at the back and side of the neck." [Wikipedia:Levator_scapulae_muscle] comment: Axial muscle group[Kardong] synonym: "levator scapul%c3%a6" RELATED [Wikipedia:Levator_scapulae_muscle] synonym: "levator scapula" RELATED [Wikipedia:Levator_scapulae_muscle] synonym: "levator scapulae muscle" RELATED [Wikipedia:Levator_scapulae_muscle] xref: FMA:32519 ! Levator scapulae xref: EHDAA2:0000992 ! levator scapulae xref: EHDAA:8309 ! levator scapulae xref: SCTID:279236008 ! Entire levator scapulae muscle is_a: UBERON:0001482 ! muscle of shoulder relationship: develops_from UBERON:0010983 {source="EHDAA2"} ! levator scapulae pre-muscle mass relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle synonym: "musculus levator scapulae" RELATED LATIN [Wikipedia:Levator_scapulae_muscle] relationship: has_muscle_insertion UBERON:0007174 {source="dbpedia", notes="Superior part of medial border of scapula"} ! medial part of scapula relationship: innervated_by UBERON:0000962 {source="dbpedia", notes="cervical nerve and dorsal scapular nerve"} ! cervical nerve relationship: has_muscle_origin UBERON:0001077 {source="dbpedia", notes="Posterior tubercles of transverse processes of C1 - C4 vertebrae"} ! transverse process of vertebra xref: http://upload.wikimedia.org/wikipedia/commons/b/bc/Levator_scapulae.png xref: AAO:0010689 ! m. levator scapulae synonym: "levator scapulae" EXACT [FMA:32519] [Term] id: UBERON:0010983 name: levator scapulae pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle xref: EHDAA2:0000993 ! levator scapulae pre-muscle mass [Term] id: UBERON:0005463 name: marginal sinus of lymph node def: "The subcapsular sinus (lymph path, lymph sinus, marginal sinus) is a region within the lymph node immediately deep to the capsule that contains relatively sparse lymphocytes. It thus allows lymph to flow freely through it. The lymph node contains lymphoid tissue, i.e. , a meshwork or fibers called reticulum with white blood cells enmeshed in it. The regions where there are few cells within the meshwork are known lymph sinus. It is lined by reticular cells, fibroblasts and fixed macrophages. Thus, subcapsular (sub=below) sinus lies immediately deep to the capsule of the lymph node and immediately above the cortex. It is continuous with the similar lymph sinuses that flank the trabeculae (the extensions of capsule within the substance of the lymph node). The subcapsular sinus is of clinical importance as it is the most likely location where the earliest manifestations of a metastatic carcinoma in a lymph node would be found." [Wikipedia:Subcapsular_sinus] comment: todo - add syns to disambiguate from rodent speen marginal sinus synonym: "subcapsular sinus" RELATED [Wikipedia:Subcapsular_sinus] synonym: "lymph path" RELATED [Wikipedia:Subcapsular_sinus] synonym: "lymph sinus" RELATED [Wikipedia:Subcapsular_sinus] synonym: "marginal sinus" EXACT [FMA:50766] xref: FMA:50766 ! marginal sinus xref: EHDAA2:0001064 ! marginal sinus xref: EHDAA:8693 ! marginal sinus is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0000029 ! lymph node xref: SCTID:361511003 ! Marginal sinus xref: ncithesaurus:Lymph_Node_Sinus ! Lymph Node Sinus xref: ncithesaurus:Lymph_Node_Subcapsular_Sinus ! Lymph Node Subcapsular Sinus xref: http://upload.wikimedia.org/wikipedia/commons/6/68/Gray597.png xref: UMLS:C1518051 xref: UMLS:C1518052 [Term] id: UBERON:0005464 name: median sacral artery def: "The median sacral artery (or middle sacral artery) is a small vessel, which arises from the back of the aorta, a little above its bifurcation. It descends in the middle line in front of the fourth and fifth lumbar vertebræ, the sacrum and coccyx, and ends in the glomus coccygeum (coccygeal gland). From it, minute branches are said to pass to the posterior surface of the rectum. On the last lumbar vertebra it anastomoses with the lumbar branch of the iliolumbar artery; in front of the sacrum it anastomoses with the lateral sacral arteries, and sends offsets into the anterior sacral foramina. It is crossed by the left common iliac vein, and is accompanied by a pair of venæ comitantes; these unite to form a single vessel, which opens into the left common iliac vein." [Wikipedia:Median_sacral_artery] synonym: "coccygeal branches" RELATED [Wikipedia:Median_sacral_artery] synonym: "middle sacral" RELATED [Wikipedia:Median_sacral_artery] synonym: "middle sacral artery" RELATED [Wikipedia:Median_sacral_artery] synonym: "Middle sacral artery" EXACT [FMA:14757] xref: FMA:14757 ! Median sacral artery xref: EHDAA2:0001087 ! median sacral artery xref: EMAPA:19214 ! median sacral artery xref: VHOG:0000756 ! median sacral artery xref: EHDAA:2556 ! median sacral artery is_a: UBERON:0004573 ! systemic artery relationship: supplies UBERON:0000159 ! anal canal relationship: supplies UBERON:0000059 ! large intestine relationship: branch_of UBERON:0001516 {source="Wikipedia"} ! abdominal aorta xref: SCTID:244282005 ! Entire median sacral artery synonym: "arteria sacralis mediana" RELATED LATIN [Wikipedia:Median_sacral_artery] xref: http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png [Term] id: UBERON:0005465 name: obturator nerve def: "The obturator nerve arises from the ventral divisions of the second, third, and fourth lumbar nerves; the branch from the third is the largest, while that from the second is often very small." [Wikipedia:Obturator_nerve] xref: FMA:16487 ! Obturator nerve xref: EHDAA2:0001282 ! obturator nerve xref: MESH:A08.800.800.720.450.600 ! obturator nerve xref: EHDAA:5657 ! obturator nerve is_a: UBERON:0001021 ! nerve relationship: part_of UBERON:0001815 ! lumbosacral nerve plexus xref: ncithesaurus:Obturator_Nerve ! Obturator Nerve xref: SCTID:181052006 ! Entire obturator nerve synonym: "nervus obturatorius" RELATED LATIN [Wikipedia:Obturator_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray344.png xref: UMLS:C0028783 [Term] id: UBERON:0005466 name: paravertebral ganglia def: "Along the length of the sympathetic trunk are ganglia known as ganglia of sympathetic trunk or paravertebral ganglia. The ganglia are distinguished as cervical, thoracic, lumbar, and sacral and, except in the neck, they closely correspond in number to the vertebrae." [Wikipedia:Paravertebral_ganglia] synonym: "ganglia of sympathetic trunk" RELATED [Wikipedia:Paravertebral_ganglia] synonym: "paravertebral ganglion" RELATED [Wikipedia:Paravertebral_ganglia] synonym: "sympathetic chain ganglia" RELATED [Wikipedia:Paravertebral_ganglia] synonym: "paravertebral ganglia" EXACT [FMA:80128] synonym: "paravertebral ganglia set" EXACT [FMA:80128] xref: FMA:80128 ! Set of paravertebral ganglia xref: EHDAA2:0001403 ! paravertebral ganglia xref: EHDAA:5635 ! paravertebral ganglia is_a: UBERON:0001806 ! sympathetic ganglion synonym: "ganglia trunci sympathici" RELATED LATIN [Wikipedia:Paravertebral_ganglia] xref: http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray847.png xref: SCTID:324478000 ! Entire sympathetic trunk ganglia synonym: "set of paravertebral ganglia" EXACT [FMA:80128] [Term] id: UBERON:0013497 name: muscularis orbicularis def: "A fringe of muscle running along the periphery of the panniculus." [UBERON:cjm] comment: Function notes: Hedgehogs roll into a ball via contraction of this muscle is_a: UBERON:0002036 ! striated muscle tissue relationship: part_of UBERON:0002416 ! integumental system synonym: "orbicularis muscle" EXACT [] synonym: "orbicularis" RELATED [] disjoint_from: UBERON:0001578 ! orbicularis oculi disjoint_from: UBERON:0010933 ! orbicularis oris muscle relationship: present_in_taxon NCBITaxon:9363 ! Erinaceidae [Term] id: UBERON:0010934 name: panniculus carnosus def: "A layer of striated muscle deep to the panniculus adiposus[WP]" [Wikipedia:Panniculus_carnosus] comment: fine, flat muscles within the hypodermis. Their origin is in the deep fascia of bone and they insert into superficial skin. They act to raise hair, quills, feathers, etc. It is also used in "twitch" reflexes to shake off insects, etc.[Palaeos] synonym: "panniculus carnosus group" EXACT [EMAPA:18189] synonym: "panniculus" BROAD [] property_value: has_relational_adjective "pannicular" xsd:string xref: EMAPA:18189 ! panniculus carnosus group is_a: UBERON:0002036 ! striated muscle tissue relationship: part_of UBERON:0002072 ! hypodermis [Term] id: UBERON:0013488 ! panniculus adiposus name: panniculus adiposus def: "The panniculus adiposus is the fatty layer of the subcutaneous tissues, superficial to a deeper vestigial layer of muscle, the panniculus carnosus. An example is the Fascia of Camper. Another example is the superficial cervical fascia[WP]" [Wikipedia:Panniculus_adiposus] comment: It includes structures that are considered fascia by some sources but not by others. synonym: "panniculus adiposus group" EXACT [] is_a: UBERON:0001013 {source="Wikipedia"} ! adipose tissue relationship: part_of UBERON:0002072 ! hypodermis relationship: present_in_taxon NCBITaxon:9261 {notes="by contraction of various parts of the panniculus carnosus, the short-beaked echidna can change shape, the most characteristic shape change being achieved by rolling itself into a ball when threatened, so protecting its belly and presenting a defensive array of sharp spines"} ! Tachyglossus aculeatus [Term] id: UBERON:0013489 name: superficial cervical fascia def: "Superficial cervical fascia is a thin layer of subcutaneous connective tissue that lies between the dermis of the skin and the deep cervical fascia. It contains the platysma, cutaneous nerves, blood, and lymphatic vessels. It also contains a varying amount of fat, which is its distinguishing characteristic." [Wikipedia:Superficial_cervical_fascia] comment: It is considered by some to be a part of the Panniculus adiposus, and not true fascia[WP] synonym: "superficial cervical fascia" EXACT [FMA:57805] synonym: "superficial layer of deep cervical fascia" EXACT [FMA:57805] synonym: "superficial layer of cervical fascia" EXACT [FMA:57805] is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0013488 {source="Wikipedia", notes="contested"} ! panniculus adiposus relationship: part_of UBERON:0013491 ! cervical fascia xref: FMA:57805 ! superficial layer of cervical fascia xref: SCTID:175208005 ! Entire superficial layer of cervical fascia [Term] id: UBERON:0013490 name: deep cervical fascia def: "The deep cervical fascia (or fascia colli in older texts) lies under cover of the Platysma, and invests the neck; it also forms sheaths for the carotid vessels, and for the structures situated in front of the vertebral column. Its attachment to the hyoid bone prevents the formation of a dewlap. The investing portion of the fascia is attached behind to the ligamentum nuchC& and to the spinous process of the seventh cervical vertebra. The \"alar fascia\" is a portion of deep cervical fascia." [Wikipedia:Deep_cervical_fascia] synonym: "fascia coli" RELATED [Wikipedia:Deep_cervical_fascia] synonym: "fascia colli" RELATED [Wikipedia:Deep_cervical_fascia] synonym: "deep cervical fascia" EXACT [FMA:21791] synonym: "deep fascia of neck" EXACT [FMA:21791] synonym: "investing layer of cervical fascia" EXACT [FMA:21791] synonym: "investing cervical fascia" EXACT [FMA:21791] xref: FMA:21791 ! investing cervical fascia is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0013491 ! cervical fascia [Term] id: UBERON:0013491 name: cervical fascia def: "The cervical fascia is fascia found in the region of the neck. It mainly refers to the deep cervical fascia. However, there are other cervical fascia: superficial cervical fascia prevertebral fascia" [Wikipedia:Cervical_fascia] synonym: "fascia of neck" EXACT [] xref: Wikipedia:Cervical_fascia ! cervical fascia xref: FMA:76866 ! cervical fascia xref: SCTID:361906006 ! Entire cervical fascia intersection_of: UBERON:0008982 ! fascia intersection_of: part_of UBERON:0000974 ! neck [Term] id: UBERON:0013492 name: prevertebral cervical fascia def: "The prevertebral fascia (or prevertebral layer of cervical fascia) is a fascia in the neck." [Wikipedia:Prevertebral_fascia] synonym: "prevertebral layer" RELATED [Wikipedia:Prevertebral_fascia] synonym: "prevertebral layer of cervical fascia" RELATED [Wikipedia:Prevertebral_fascia] synonym: "lamina prevertebralis (fascia cervicalis)" EXACT [FMA:46560] synonym: "prevertebral fascia" EXACT [FMA:46560] synonym: "prevertebral layer of deep cervical fascia" EXACT [FMA:46560] synonym: "prevertebral layer of cervical fascia" EXACT [FMA:46560] xref: FMA:46560 ! prevertebral layer of cervical fascia xref: SCTID:175407002 ! Entire prevertebral layer of cervical fascia is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0013491 ! cervical fascia [Term] id: UBERON:0013493 ! abdominal fascia name: abdominal fascia synonym: "endo-abdominopelvic fascia" EXACT [FMA:19841] synonym: "fascia of abdomen" EXACT [FMA:19841] xref: FMA:19841 ! abdominal fascia intersection_of: UBERON:0008982 ! fascia intersection_of: part_of UBERON:0000916 ! abdomen xref: SCTID:306708007 ! Entire fascia of abdomen [Term] id: UBERON:0007809 name: fascia of Camper def: "The superficial layer (fascia of Camper) is a thick superficial layer of the anterior abdominal wall. It is areolar in texture, and contains in its meshes a varying quantity of adipose tissue. It is found superficial to Scarpa's fascia." [Wikipedia:Fascia_of_Camper] synonym: "Camper's fascia" EXACT [Wikipedia:Fascia_of_Camper] synonym: "adipose layer of superficial fascia of abdomen" EXACT [FMA:19922] synonym: "camper's fascia" EXACT [FMA:19922] synonym: "fatty layer of subcutaneous tissue of abdomen" EXACT [FMA:19922] synonym: "intermediate investing fascia of abdomen" EXACT [FMA:19922] synonym: "superficial layer of superficial fascia of abdomen" EXACT [FMA:19922] synonym: "fatty layer of superficial fascia of abdomen" EXACT [FMA:19922] xref: FMA:19922 ! fatty layer of superficial fascia of abdomen is_a: UBERON:0001013 {source="Wikipedia"} ! adipose tissue relationship: part_of UBERON:0006635 {source="FMA"} ! anterior abdominal wall relationship: part_of UBERON:0013493 ! abdominal fascia relationship: part_of UBERON:0013488 {source="Wikipedia"} ! panniculus adiposus synonym: "fascia investiens intermedia abdominis" EXACT LATIN [FMA:TA, FMA:19922] synonym: "panniculus adiposus telae subcutaneae abdominis" EXACT LATIN [FMA:TA, FMA:19922] synonym: "panniculus adiposus abdominis" RELATED LATIN [Wikipedia:Fascia_of_Camper] xref: http://upload.wikimedia.org/wikipedia/commons/2/28/Gray393.png [Term] id: UBERON:0005467 name: platysma def: "The platysma is a superficial muscle that overlaps the sternocleidomastoid. It is a broad sheet arising from the fascia covering the upper parts of the pectoralis major and deltoid; its fibers cross the clavicle, and proceed obliquely upward and medially along the side of the neck. The anterior fibers interlace, below and behind the symphysis menti, with the fibers of the muscle of the opposite side; the posterior fibers cross the mandible, some being inserted into the bone below the oblique line, others into the skin and subcutaneous tissue of the lower part of the face. Many of these fibers blend with the muscles about the angle and lower part of the mouth. Sometimes fibers can be traced to the zygomaticus, or to the margin of the orbicularis oculi. Beneath the platysma, the external jugular vein descends from the angle of the mandible to the clavicle." [Wikipedia:Platysma_muscle] comment: Human variation notes: Variations occur in the extension over the face and over the clavicle and shoulder; it may be absent or interdigitate with the muscle of the opposite side in front of the neck; attachment to clavicle, mastoid process or occipital bone occurs. A more or less independent fasciculus, the occipitalis minor, may extend from the fascia over the trapezius to fascia over the insertion of the sternocleidomastoideus. synonym: "neck platysma muscle" RELATED [BTO:0005124] synonym: "platysma muscle" EXACT [BTO:0005124] synonym: "platysma myoides" NARROW SENSU [PMID:19531159] synonym: "platysma cervicale" NARROW SENSU [PMID:19531159] xref: FMA:45738 ! Platysma xref: EHDAA2:0001474 ! platysma xref: EMAPA:18190 ! platysma xref: VHOG:0000931 ! platysma xref: EHDAA:8270 ! platysma xref: BTO:0005124 ! platysma muscle is_a: UBERON:0002377 ! muscle of neck is_a: UBERON:0001577 {source="FEED"} ! facial nerve muscle relationship: part_of UBERON:0010934 {source="EMAPA"} ! panniculus carnosus relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm xref: SCTID:244754004 ! Entire platysma muscle xref: ncithesaurus:Platysma_Myoides ! platysma myoides relationship: has_muscle_insertion UBERON:0000165 {source="dbpedia", notes="base of mandible; skin of cheek and lower lip; angle of mouth; orbicularis oris"} ! mouth relationship: has_muscle_insertion UBERON:0010933 {source="dbpedia", notes="base of mandible; skin of cheek and lower lip; angle of mouth; orbicularis oris"} ! orbicularis oris muscle relationship: innervated_by UBERON:0000962 {source="dbpedia", notes="cervical branch of the facial nerve"} ! cervical nerve xref: http://upload.wikimedia.org/wikipedia/commons/f/fb/Platysma.png property_value: external_definition "The platysma is a pharyngeal arch 2 muscle and a superficial facial muscle that participates in oral/pharyngeal behaviors and is innervated by the cervical branch of the facial nerve, and attaches to the skin.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} property_value: homology_notes "One of these (facial muscles in mammals), the platysma, is an unspecialized muscle derived from the hyoid arch.[well established][VHOG]" xsd:string {external_class="VHOG:0000931", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.398", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1514163 [Term] id: UBERON:0013635 name: sphincter colli muscle comment: The m. sphincter in the head region can be divided into 2 layers: M. sphincter colli profundus and superficialis; in studied placentals, the deepest layer has circular fibers, while the superficial layer has oblique and longitudinal fibers. In non-mammalian vertebrates (if differenciated) and in monotremes both the superficialis and the profundus layers are circular ("sphincter") muscles (Shumacher, 1956; Saban, 1971). ^n^nM. sphincter colli superficialis is present in Lagomorpha but absent in Rodentia (Meinertz, 1941, 1942; Ryan, 1989; Rinker, 1954). Some errouneous references of this muscle in rodents (e.g., Bezuidenhout and Evans, 2005) are due to decussating fibers of the deep sphincter, which creates a false superficial sphincter (Ryan, 1989).[MorphoBank] is_a: UBERON:0002377 ! muscle of neck synonym: "sphincter colli" EXACT [] [Term] id: UBERON:0011508 name: sphincter colli superficialis muscle def: "The sphincter colli superficialis is composed of transverse muscle fibers, and covers the entire area between the lower jaw and chest. The muscle is used to tighten the skin on the underside of the throat." [http://de.wikipedia.org/wiki/Platysma] is_a: UBERON:0002377 ! muscle of neck relationship: part_of UBERON:0013635 ! sphincter colli muscle xref: MA:0002380 ! sphincter colli superficialis synonym: "sphincter colli superficialis" EXACT [MA:0002380] synonym: "M. sphincter colli superficialis" EXACT [] [Term] id: UBERON:0011509 name: sphincter colli profundus muscle def: "The sphincter colli profundus of lie below the platysma in the area of the parotid gland (gland regions)." [http://de.wikipedia.org/wiki/Platysma] comment: The muscles of the mid and upper face derive from the embryonic sphincter colli profundus muscle is_a: UBERON:0002377 ! muscle of neck relationship: part_of UBERON:0013635 ! sphincter colli muscle synonym: "sphincter colli profundus" EXACT [] synonym: "M. sphincter colli profundus" EXACT [] [Term] id: UBERON:0005474 name: obsolete second polar body comment: belongs in CL synonym: "Polocytus secundarius" EXACT [FMA:18651] consider: FMA:18651 ! Second polar body consider: EHDAA2:0001820 ! second polar body is_obsolete: true [Term] id: UBERON:0005476 name: spinal nerve trunk synonym: "spinal nerve (trunk)" EXACT [FMA:5929] synonym: "spinal neural trunk" EXACT [FMA:5929] synonym: "trunk of spinal nerve" EXACT [FMA:5929] xref: FMA:5929 ! Trunk of spinal nerve xref: EHDAA2:0001900 ! spinal nerve trunk intersection_of: UBERON:0002464 ! nerve trunk intersection_of: part_of UBERON:0001780 ! spinal nerve def: "A nerve trunk that is part of a spinal nerve." [OBOL:automatic] [Term] id: UBERON:0005477 name: stomach fundus epithelium synonym: "gastric epithelium of fundus" EXACT [FMA:17277] synonym: "gastric fundus epithelium" EXACT [FMA:17277] synonym: "epithelium of fundus of stomach" EXACT [FMA:17277] xref: FMA:17277 ! Epithelium of fundus of stomach xref: EHDAA2:0001921 ! stomach fundus epithelium xref: VHOG:0000878 ! fundus epithelium intersection_of: UBERON:0000485 ! simple columnar epithelium intersection_of: part_of UBERON:0001160 ! fundus of stomach relationship: part_of UBERON:0004994 ! mucosa of fundus of stomach def: "A simple columnar epithelium that is part of a fundus of stomach." [OBOL:automatic] [Term] id: UBERON:0005488 ! superior mesenteric plexus name: superior mesenteric plexus def: "The superior mesenteric plexus is a continuation of the lower part of the celiac plexus, receiving a branch from the junction of the right vagus nerve with the plexus. It surrounds the superior mesenteric artery, accompanies it into the mesentery, and divides into a number of secondary plexuses, which are distributed to all the parts supplied by the artery, viz. , pancreatic branches to the pancreas; intestinal branches to the small intestine; and ileocolic, right colic, and middle colic branches, which supply the corresponding parts of the great intestine. The nerves composing this plexus are white in color and firm in texture; in the upper part of the plexus close to the origin of the superior mesenteric artery is the superior mesenteric ganglion." [Wikipedia:Superior_mesenteric_plexus] synonym: "superior mesenteric nerve plexus" EXACT [FMA:6639] xref: FMA:6639 ! superior mesenteric nerve plexus is_a: UBERON:0001816 ! autonomic nerve plexus synonym: "plexus mesentericus superior" EXACT LATIN [FMA:TA, FMA:6639] xref: SCTID:362493003 ! Entire superior mesenteric plexus synonym: "plexus mesentericus superior" RELATED LATIN [Wikipedia:Superior_mesenteric_plexus] xref: http://upload.wikimedia.org/wikipedia/commons/6/63/Gray848.png [Term] id: UBERON:0005479 name: superior mesenteric ganglion def: "In the upper part of the superior mesenteric plexus close to the origin of the superior mesenteric artery is a ganglion, the superior mesenteric ganglion. The superior mesenteric ganglion is the synapsing point for one of the pre- and post-synaptic nerves of the sympathetic division of the autonomous nervous system. This nerve goes on to innervate part of the large intestine." [Wikipedia:Superior_mesenteric_ganglion] synonym: "ganglion mesentericum superius" RELATED [Wikipedia:Superior_mesenteric_ganglion] synonym: "superior mesenteric ganglia" RELATED [Wikipedia:Superior_mesenteric_ganglion] xref: FMA:77589 ! Superior mesenteric ganglion xref: EHDAA2:0001950 ! superior mesenteric ganglion xref: EHDAA:8950 ! superior mesenteric ganglion is_a: UBERON:0003964 ! prevertebral ganglion relationship: part_of UBERON:0005488 ! superior mesenteric plexus xref: SCTID:279276003 ! Superior mesenteric ganglion synonym: "ganglion mesentericum superius" RELATED LATIN [Wikipedia:Superior_mesenteric_ganglion] xref: http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png [Term] id: UBERON:0005480 name: superior orbital fissure def: "The superior orbital fissure is a foramen in the skull, although strictly it is more of a cleft, lying between the lesser and greater wings of the sphenoid bone." [Wikipedia:Superior_orbital_fissure] comment: TODO add generic foramen class synonym: "fissura orbitalis superior" RELATED [Wikipedia:Superior_orbital_fissure] synonym: "sphenoidal fissure" RELATED [Wikipedia:Superior_orbital_fissure] xref: FMA:54799 ! Superior orbital fissure xref: EHDAA2:0001952 ! superior orbital fissure xref: EMAPA:18718 ! superior of orbital fissure xref: VHOG:0000553 ! superior orbital fissure xref: EHDAA:10650 ! superior of orbital fissure is_a: UBERON:0005744 ! cranial conduit relationship: part_of UBERON:0003129 ! skull xref: SCTID:280559002 ! Entire superior orbital fissure synonym: "fissura orbitalis superior" RELATED LATIN [Wikipedia:Superior_orbital_fissure] xref: http://upload.wikimedia.org/wikipedia/commons/8/8e/Orbita_mensch.jpg [Term] id: UBERON:0005481 name: tentorial sinus def: "The straight sinus (also known by the alternate anatomical term tentorial sinus), within the human head, is an area beneath the brain, which allows blood veins to span the area, from the center of the head towards the back. It drains from the inferior sagittal sinus (from the center of the brain) to the transverse sinuses (at the back of the head), then to the sigmoid sinuses below the brain. See diagram (at right): labeled in the brain as \"\" . The straight sinus (tentorial sinus) is situated along the junction of the falx cerebri and the tentorium cerebelli. It forms from the confluence of the inferior sagittal sinus and great cerebral vein (great vein of Galen). In cross-section it is triangular, contains a few transverse bands across its interior, and increases in size as it proceeds backward. It receives the superior cerebellar veins. The terminal part of the straight sinus drains into the confluence of the sinuses." [Wikipedia:Straight_sinus] comment: retired in ncit synonym: "rectus sinus" RELATED [Wikipedia:Straight_sinus] synonym: "straight sinus vein" RELATED [Wikipedia:Straight_sinus] synonym: "straight sinus" RELATED [Wikipedia:Straight_sinus] xref: FMA:50769 ! Straight sinus xref: EHDAA2:0002003 ! tentorial sinus xref: EHDAA:9882 ! tentorial sinus is_a: UBERON:0001638 ! vein xref: ncithesaurus:Straight_Sinus ! Straight Sinus synonym: "sinus rectus" RELATED LATIN [Wikipedia:Straight_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray488_blue.gif xref: SCTID:279261006 ! Entire straight sinus [Term] id: UBERON:0011741 ! cardiac valve leaflet name: cardiac valve leaflet is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000946 ! cardial valve [Term] id: UBERON:0011742 name: aortic valve leaflet intersection_of: UBERON:0011741 ! cardiac valve leaflet intersection_of: part_of UBERON:0002137 ! aortic valve relationship: part_of UBERON:0010172 {source="MP"} ! bulb of aorta xref: VHOG:0000819 ! aortic valve leaflets xref: EMAPA:18627 ! leaflets synonym: "aortic valve leaflets" EXACT [VHOG:0000819] property_value: homology_notes "Extensive conservation of valve developmental mechanisms also has been observed among vertebrate species including chicken, mouse, and human.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000819", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A cardiac valve leaflet that is part of a aortic valve." [OBOL:automatic] [Term] id: UBERON:0011745 name: pulmonary valve leaflets intersection_of: UBERON:0011741 ! cardiac valve leaflet intersection_of: part_of UBERON:0002146 ! pulmonary valve xref: VHOG:0000820 ! pulmonary valve leaflets xref: EMAPA:18629 ! leaflets property_value: homology_notes "Extensive conservation of valve developmental mechanisms also has been observed among vertebrate species including chicken, mouse, and human.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000820", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A cardiac valve leaflet that is part of a pulmonary valve." [OBOL:automatic] [Term] id: UBERON:0005484 name: tricuspid valve leaflet synonym: "tricuspid valve leaflet" EXACT [FMA:7237] synonym: "tricuspid valvular leaflet" EXACT [FMA:7237] synonym: "leaflet of tricuspid valve" EXACT [FMA:7237] xref: FMA:7237 ! Leaflet of tricuspid valve xref: RETIRED_EHDAA2:0002082 ! tricuspid valve leaflets xref: EMAPA:18630 ! leaflets of tricuspid valve xref: VHOG:0000821 ! tricuspid valve leaflets intersection_of: UBERON:0011741 ! cardiac valve leaflet intersection_of: part_of UBERON:0002134 ! tricuspid valve xref: SCTID:276830008 ! Entire leaflet of tricuspid valve synonym: "tricuspid valve leaflets" EXACT [VHOG:0000821] property_value: homology_notes "The mature AV (atrioventricular) valve of the adult zebrafish 2-chambered heart is structurally similar to the mammalian AV valves with stratified ECM (extracellular matrix) and supporting chordae tendineae. Therefore, the major cellular and molecular events of valve development are largely conserved among animals with hearts composed of multiple chambers.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000821", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A cardiac valve leaflet that is part of a tricuspid valve." [OBOL:automatic] [Term] id: UBERON:0005485 name: valve of inferior vena cava def: "The valve of the inferior vena cava (eustachian valve) lies at the junction of the inferior vena cava and right atrium. In fetal life, the Eustachian valve helps direct the flow of oxygen-rich blood through the right atrium into the left atrium via the foramen ovale (preventing blood flowing into the right ventricle). Before birth, oxygen rich blood returning from the placenta mixes with blood from the hepatic veins in the inferior vena cava. Streaming this blood across the atrial septum via the foramen ovale increases the oxygen content of blood in the left atrium. This in turn increases the oxygen concentration of blood in the left ventricle, the aorta, the coronary circulation and the circulation of the developing brain. Following birth and separation from the placenta, the oxygen content in the inferior vena cava falls. With the onset of breathing, the left atrium receives oxygen-rich blood from the lungs via the pulmonary veins. As blood flow to the lungs increases, the amount of blood flow entering the left atrium increases. When the pressure in the left atrium exceeds the pressure in the right atrium, the foramen ovale begins to close and limits the blood flow between the left and right atrium. While the Eustachian valve persists in adult life, it is essentially vestigial. Eustachian Valve (EV), also called valvulae venae cavae inferioris, was described for the first time by the Italian anatomist: Bartolomeo Eustachi (born between 1500 and 1513, died 1574)." [Wikipedia:Valve_of_inferior_vena_cava] comment: editor note: this class should be subdivided into the embryonic structure and the vestigial adult remnant, a small endocardialfold synonym: "valve of the inferior vena cava" RELATED [Wikipedia:Valve_of_inferior_vena_cava] synonym: "eustachean valve" EXACT [FMA:9240] synonym: "eustachian valve" EXACT [FMA:9240] synonym: "inferior vena cava valve" EXACT [FMA:9240] xref: FMA:9240 ! Valve of inferior vena cava xref: EHDAA2:0002166 ! valve of inferior vena cava xref: EHDAA:8631 ! valve of inferior vena cava is_a: UBERON:0000946 ! cardial valve relationship: part_of UBERON:0001072 ! inferior vena cava xref: ncithesaurus:Eustachian_Valve ! Eustachian Valve xref: SCTID:277722006 ! Entire valve of inferior vena cava synonym: "valvula venae cavae inferioris" RELATED LATIN [Wikipedia:Valve_of_inferior_vena_cava] xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png xref: UMLS:C0225848 [Term] id: UBERON:0006615 ! venous sinus name: venous sinus def: "a large vein or channel for the circulation of venous blood" [http://medical-dictionary.thefreedictionary.com/venous+sinus] comment: todo - add subclasses xref: MA:0000070 ! venous sinus is_a: UBERON:0003920 ! venous blood vessel xref: ncithesaurus:Venous_Sinus ! Venous Sinus xref: SCTID:341586007 ! Entire venous sinus xref: UMLS:C0226504 [Term] id: UBERON:0005486 name: venous dural sinus def: "The dural venous sinuses (also called dural sinuses, cerebral sinuses, or cranial sinuses) are venous channels found between layers of dura mater in the brain.[1] They receive blood from internal and external veins of the brain, receive cerebrospinal fluid (CSF) from the subarachnoid space, and ultimately empty into the internal jugular vein." [Wikipedia:Dural_venous_sinuses] comment: editor note: the MA placement should be checked synonym: "cranial dural venous sinus" EXACT [FMA:50762] synonym: "venous dural sinus" EXACT [EHDAA2:0002169] synonym: "dural sinus" EXACT [FMA:50762] synonym: "venous dural" EXACT [EHDAA:6491] synonym: "dural venous sinus" EXACT [FMA:50762] xref: FMA:50762 ! Dural venous sinus xref: EHDAA2:0002169 ! venous dural sinus xref: EHDAA:6491 ! venous dural xref: MA:0002113 ! dural vein xref: EMAPA:18634 ! venous dural xref: VHOG:0001004 ! venous dural is_a: UBERON:0006615 ! venous sinus relationship: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0003711 ! brachiocephalic vein xref: SCTID:54944003 ! Dural sinus synonym: "s. durae matris" RELATED LATIN [Wikipedia:Dural_venous_sinuses] xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray488_blue.gif synonym: "dural vein" EXACT [MA:0002113] [Term] id: UBERON:0005475 name: sigmoid sinus def: "a portion of the lateral venous sinus, bulging prominently into the mastoid cavity, that serves as a principal conduit by which blood leaves the cranium[EPIC]. The sigmoid is drained by the internal jugular vein" [Wikipedia:Sigmoid_sinus, http://palaeos.com/vertebrates/glossary/glossaryS.html] xref: FMA:50782 ! Sigmoid sinus xref: EHDAA2:0001838 ! sigmoid sinus xref: EMAPA:19060 ! sigmoid xref: VHOG:0001337 ! sigmoid sinus xref: EHDAA:9880 ! sigmoid sinus is_a: UBERON:0005486 ! venous dural sinus relationship: part_of UBERON:0000033 ! head relationship: tributary_of UBERON:0001586 {source="Palaeos"} ! internal jugular vein xref: ncithesaurus:Sigmoid_Sinus ! Sigmoid Sinus xref: SCTID:279264003 ! Entire sigmoid sinus synonym: "sulcus sigmoideus" RELATED LATIN [Wikipedia:Sigmoid_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray488_blue.gif property_value: external_definition "The sigmoid sinuses, within a human head, are 2 areas beneath the brain, which allow blood veins to span the area, from the center of the head downward. They drain from the transverse sinuses (under the back of the brain) to the internal jugular vein. Each sigmoid sinus begins beneath the temporal bone and follows a tortuous course to the jugular foramen, at which point the sinus becomes continuous with the internal jugular vein[Wikipedia:Sigmoid_sinus]." xsd:string {source="Wikipedia:Sigmoid_sinus"} [Term] id: UBERON:0005491 name: glossopharyngeal neural crest def: "Cranial neural crest which gives rise to the glossopharyngeal ganglion." [ZFA:0007066] subset: vertebrate_core xref: ZFA:0007066 ! glossopharyngeal neural crest xref: EHDAA2:0000714 ! glossopharyngeal neural crest xref: EHDAA:660 ! glossopharyngeal neural crest is_a: UBERON:0003099 ! cranial neural crest xref: TAO:0007066 ! glossopharyngeal neural crest [Term] id: UBERON:0005496 ! neural tube lateral wall name: neural tube lateral wall def: "Portion of tissue on the side of the lumen of the neural tube." [ZFA:0001435] subset: vertebrate_core synonym: "lateral wall neural tube" EXACT [ZFA:0001435] xref: ZFA:0001435 ! lateral wall neural tube xref: EHDAA2:0001257 ! neural tube lateral wall xref: EHDAA:2873 ! lateral wall xref: EHDAA:912 ! lateral wall xref: VHOG:0000513 ! lateral wall spinal cord is_a: UBERON:0000060 ! anatomical wall relationship: part_of UBERON:0001049 ! neural tube xref: TAO:0001435 ! lateral wall neural tube [Term] id: UBERON:0005495 name: midbrain lateral wall synonym: "lateral wall midbrain" EXACT [ZFA:0000906] xref: ZFA:0000906 ! lateral wall midbrain xref: EHDAA2:0001171 ! midbrain lateral wall xref: EMAPA:16976 ! lateral wall of midbrain xref: VHOG:0000455 ! lateral wall midbrain xref: EHDAA:3700 ! lateral wall of midbrain is_a: UBERON:0005496 ! neural tube lateral wall relationship: part_of UBERON:0001891 ! midbrain xref: TAO:0000906 ! lateral wall midbrain synonym: "lateral wall mesencephalon" RELATED [VHOG:0000455] [Term] id: UBERON:0005591 name: diencephalon lateral wall synonym: "lateral wall diencephalon" EXACT [ZFA:0000780] xref: ZFA:0000780 ! lateral wall diencephalon xref: EHDAA2:0000396 ! diencephalon lateral wall xref: EMAPA:16650 ! lateral wall of diencephalon of future forebrain xref: EMAPA:16905 ! lateral wall of diencephalon of forebrain xref: VHOG:0000596 ! lateral wall diencephalon xref: EHDAA:1977 ! lateral wall of diencephalon of prosencephalon is_a: UBERON:0005496 ! neural tube lateral wall relationship: part_of UBERON:0001894 ! diencephalon xref: TAO:0000780 ! lateral wall diencephalon [Term] id: UBERON:0009582 name: spinal cord lateral wall synonym: "lateral wall spinal cord" EXACT [ZFA:0000996] is_a: UBERON:0005496 ! neural tube lateral wall relationship: part_of UBERON:0002240 {source="EMAPA"} ! spinal cord xref: EMAPA:17579 ! lateral wall of spinal cord of central nervous system of nervous system of organ system xref: ZFA:0000996 ! lateral wall spinal cord xref: TAO:0000996 ! lateral wall spinal cord xref: EFO:0003602 ! lateral wall spinal cord [Term] id: UBERON:0005499 name: rhombomere 1 def: "Hindbrain segment or neuromere 1." [ZFA:0001031] subset: vertebrate_core synonym: "r1" EXACT [ZFA:0001031] xref: ZFA:0001031 ! rhombomere 1 xref: EHDAA2:0001637 ! rhombomere 1 xref: EMAPA:16290 ! rhombomere 01 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16480 ! rhombomere 01 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16918 ! rhombomere 01 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17092 ! rhombomere 01 of metencephalon xref: EFO:0003608 ! rhombomere 1 is_a: UBERON:0001892 ! rhombomere relationship: develops_from UBERON:0007289 {evidence="definitional"} ! presumptive rhombomere 1 property_value: rhombomere_number "1" xsd:nonNegativeInteger xref: TAO:0001031 ! rhombomere 1 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001031", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005500 ! rhombomere floor plate name: rhombomere floor plate xref: EHDAA2:0004324 ! rhombencephalon floor plate synonym: "rhombencephalon floor plate" EXACT [EHDAA2:0004324] xref: VHOG:0001019 ! floor plate rhombomeres xref: ZFA:0001258 ! floor plate rhombomere region synonym: "floor plate rhombomere region" EXACT [ZFA:0001258] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0001892 ! rhombomere xref: TAO:0001258 ! floor plate hindbrain synonym: "floor plate hindbrain" EXACT [VHOG:0001019] synonym: "floor plate rhombencephalon" RELATED [VHOG:0001019] synonym: "floorplate hindbrain" RELATED [VHOG:0001019] property_value: homology_notes "In summary, the available data for tunicates, amphioxus, and vertebrates indicate that a floorplate-like structure was already present in the proximate invertebrate ancestor of the vertebrates and that the genetic mechanisms for DV patterning of the nerve cord were also largely in place.[well established][VHOG]" xsd:string {external_class="VHOG:0001019", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND\, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005501 ! rhombomere lateral wall name: rhombomere lateral wall intersection_of: UBERON:0005496 ! neural tube lateral wall intersection_of: part_of UBERON:0001892 ! rhombomere def: "A neural tube lateral wall that is part of a rhombomere." [OBOL:automatic] [Term] id: UBERON:0005502 ! rhombomere roof plate name: rhombomere roof plate xref: VHOG:0001018 ! roof plate rhombomeres xref: ZFA:0001311 ! roof plate rhombomere region synonym: "roof plate rhombomere region" EXACT [ZFA:0001311] is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0001892 ! rhombomere xref: TAO:0001311 ! roof plate rhombomere synonym: "roof plate rhombomeres" EXACT [VHOG:0001018] synonym: "roof plate rhombomere" EXACT [TAO:0001311] [Term] id: UBERON:0005507 name: rhombomere 3 subset: vertebrate_core synonym: "r3" EXACT [ZFA:0000948] xref: ZFA:0000948 ! rhombomere 3 xref: EHDAA2:0001657 ! rhombomere 3 xref: EMAPA:16297 ! rhombomere 03 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16488 ! rhombomere 03 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16932 ! rhombomere 03 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17106 ! rhombomere 03 of myelencephalon xref: EFO:0003596 ! rhombomere 3 is_a: UBERON:0001892 ! rhombomere xref: XAO:0004081 ! rhombomere R3 relationship: develops_from UBERON:0007290 {evidence="definitional"} ! presumptive rhombomere 3 property_value: rhombomere_number "3" xsd:nonNegativeInteger xref: TAO:0000948 ! rhombomere 3 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000948", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005511 name: rhombomere 4 subset: vertebrate_core synonym: "r4" EXACT [ZFA:0001032] xref: ZFA:0001032 ! rhombomere 4 xref: EHDAA2:0001667 ! rhombomere 4 xref: EMAPA:16301 ! rhombomere 04 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16492 ! rhombomere 04 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16939 ! rhombomere 04 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17113 ! rhombomere 04 of myelencephalon xref: EFO:0003609 ! rhombomere 4 is_a: UBERON:0001892 ! rhombomere xref: XAO:0004082 ! rhombomere R4 relationship: develops_from UBERON:0007291 {evidence="definitional"} ! presumptive rhombomere 4 property_value: rhombomere_number "4" xsd:nonNegativeInteger xref: TAO:0001032 ! rhombomere 4 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001032", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005515 name: rhombomere 5 subset: vertebrate_core synonym: "r5" EXACT [ZFA:0000823] xref: ZFA:0000823 ! rhombomere 5 xref: EHDAA2:0001677 ! rhombomere 5 xref: EMAPA:16305 ! rhombomere 05 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16496 ! rhombomere 05 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16946 ! rhombomere 05 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17120 ! rhombomere 05 of myelencephalon xref: EFO:0003580 ! rhombomere 5 is_a: UBERON:0001892 ! rhombomere xref: XAO:0004083 ! rhombomere R5 relationship: develops_from UBERON:0007292 {evidence="definitional"} ! presumptive rhombomere 5 property_value: rhombomere_number "5" xsd:nonNegativeInteger xref: TAO:0000823 ! rhombomere 5 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000823", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005519 name: rhombomere 6 subset: vertebrate_core synonym: "r6" EXACT [ZFA:0000069] xref: ZFA:0000069 ! rhombomere 6 xref: EHDAA2:0001687 ! rhombomere 6 xref: EMAPA:16500 ! rhombomere 06 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16953 ! rhombomere 06 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17127 ! rhombomere 06 of myelencephalon xref: EFO:0003480 ! rhombomere 6 is_a: UBERON:0001892 ! rhombomere xref: XAO:0004084 ! rhombomere R6 relationship: develops_from UBERON:0007293 {evidence="definitional"} ! presumptive rhombomere 6 property_value: rhombomere_number "6" xsd:nonNegativeInteger xref: TAO:0000069 ! rhombomere 6 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000069", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005523 name: rhombomere 7 subset: vertebrate_core synonym: "r7" EXACT [ZFA:0000949] xref: ZFA:0000949 ! rhombomere 7 xref: EHDAA2:0001697 ! rhombomere 7 xref: EMAPA:16504 ! rhombomere 07 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16960 ! rhombomere 07 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17134 ! rhombomere 07 of myelencephalon xref: EFO:0003597 ! rhombomere 7 is_a: UBERON:0001892 ! rhombomere relationship: develops_from UBERON:0007294 {evidence="definitional"} ! presumptive rhombomere 7 property_value: rhombomere_number "7" xsd:nonNegativeInteger xref: TAO:0000949 ! rhombomere 7 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000949", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005527 name: rhombomere 8 subset: vertebrate_core synonym: "r8" EXACT [ZFA:0000153] xref: ZFA:0000153 ! rhombomere 8 xref: EHDAA2:0001707 ! rhombomere 8 xref: EMAPA:16508 ! rhombomere 08 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16967 ! rhombomere 08 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17141 ! rhombomere 08 of myelencephalon xref: EFO:0003500 ! rhombomere 8 is_a: UBERON:0001892 ! rhombomere relationship: develops_from UBERON:0007295 {evidence="definitional"} ! presumptive rhombomere 8 property_value: rhombomere_number "8" xsd:nonNegativeInteger xref: TAO:0000153 ! rhombomere 8 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000153", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005561 name: telencephalon lateral wall subset: vertebrate_core synonym: "lateral wall telencephalon" EXACT [ZFA:0000785] xref: ZFA:0000785 ! lateral wall telencephalon xref: EHDAA2:0001985 ! telencephalon lateral wall xref: EMAPA:16656 ! lateral wall of telencephalon of future forebrain xref: VHOG:0000023 ! telencephalon lateral wall xref: EHDAA:3504 ! lateral wall of telencephalon is_a: UBERON:0005496 ! neural tube lateral wall relationship: part_of UBERON:0001893 ! telencephalon xref: TAO:0000785 ! lateral wall telencephalon property_value: external_definition "Lateral wall that is part of the telencephalon. [Bgee_curator][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000023", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005562 name: thymus primordium def: "A small outgrowth of the pharyngeal epithelium that is the site of lymphocyte cell production[ZFA]. [PMID]." [ZFA:0001077] comment: Editor notes: we follow Kardong table 13.1 in having some developmental contribution of pouch 4 in mammals, but this isn't reflected in EHDAA2. Development notes: Consider adding distinct term for mesenchyme (see EHDAA2), to indicate NC constribution. Taxon notes: variability of developmental origin: In fish, thymic primordia are generated by all the pouches except the first. However, in avians the thymus arises from pouches 3 and 4, whereas in humans it is only generated by the third pouch[PMID:16313389] The thymus arises from the second pouch in frogs, 2-6 in cartilaginous fish, 2-3 in reptiles, 3 or 4 in bony fish, birds and mammals. The final number is variable - 5 paired organs in sharks, 4 in caecilians, 3 in urodeles, 1 in many teleost, anurans and many mammals[ISBN-10:0781714125] subset: vertebrate_core synonym: "thymic rudiment" EXACT [ZFA:0001077] synonym: "thymic primordium" EXACT [OBOL:automatic] xref: ZFA:0001077 ! thymus primordium xref: EHDAA2:0002023 ! thymus primordium xref: EMAPA:17523 ! thymus primordium of gland of foregut xref: EMAPA:18536 ! thymus primordium of haemolymphoid system of gland of organ system xref: EHDAA:2969 ! thymus primordium xref: EFO:0003622 ! thymus primordium is_a: UBERON:0000483 {source="ZFA"} ! epithelium is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0000974 {source="EHDAA2"} ! neck relationship: part_of UBERON:0003295 {source="EHDAA2"} ! gland of pharynx relationship: has_developmental_contribution_from UBERON:0005428 {source="ZFA", notes="mesenchymal", source="UBERONREF:0000002"} ! vagal neural crest relationship: has_developmental_contribution_from UBERON:0010023 {gci_relation="part_of", gci_filler="NCBITaxon:7778", notes="Elasmobranchii", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 2 relationship: has_developmental_contribution_from UBERON:0010025 {gci_relation="part_of", gci_filler="NCBITaxon:7778", notes="Elasmobranchii", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010027 {gci_relation="part_of", gci_filler="NCBITaxon:7778", notes="Elasmobranchii", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010029 {gci_relation="part_of", gci_filler="NCBITaxon:7778", notes="Elasmobranchii", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 5 relationship: develops_from UBERON:0010023 {gci_relation="part_of", gci_filler="NCBITaxon:8342", notes="Anuran", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 2 relationship: has_developmental_contribution_from UBERON:0010023 {gci_relation="part_of", gci_filler="NCBITaxon:8504", notes="Lizard", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 2 relationship: has_developmental_contribution_from UBERON:0010025 {gci_relation="part_of", gci_filler="NCBITaxon:8504", notes="Lizard", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010025 {gci_relation="part_of", gci_filler="NCBITaxon:8459", notes="Turtles", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010027 {gci_relation="part_of", gci_filler="NCBITaxon:8459", notes="Turtles", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010027 {gci_relation="part_of", gci_filler="NCBITaxon:8570", notes="Snakes", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010029 {gci_relation="part_of", gci_filler="NCBITaxon:8570", notes="Snakes", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 5 relationship: has_developmental_contribution_from UBERON:0010025 {gci_relation="part_of", gci_filler="NCBITaxon:8293", notes="Urodele", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010027 {gci_relation="part_of", gci_filler="NCBITaxon:8293", notes="Urodele", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010029 {gci_relation="part_of", gci_filler="NCBITaxon:8293", notes="Urodele", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 5 relationship: has_developmental_contribution_from UBERON:0010025 {gci_relation="part_of", gci_filler="NCBITaxon:8782", notes="Aves", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010027 {gci_relation="part_of", gci_filler="NCBITaxon:8782", notes="Aves", source="ISBN10:0073040584-table13.1"} ! dorsal part of pharyngeal pouch 4 relationship: has_developmental_contribution_from UBERON:0010026 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="Mammals", source="ISBN10:0073040584-table13.1", source="EHDAA2"} ! ventral part of pharyngeal pouch 3 relationship: has_developmental_contribution_from UBERON:0010028 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="Mammals", source="ISBN10:0073040584-table13.1"} ! ventral part of pharyngeal pouch 4 relationship: develops_from UBERON:0007690 {source="ZFA"} ! early pharyngeal endoderm relationship: part_of UBERON:0002405 {source="ZFA"} ! immune system xref: TAO:0001077 ! thymus primordium property_value: external_definition "A small outgrowth of the pharyngeal epithelium that is the site of lymphocyte cell production. Willett et al, 1999.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001077", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0008817 name: thymus primordium endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0005562 ! thymus primordium relationship: has_developmental_contribution_from UBERON:0007124 {source="PMID:16313389"} ! pharyngeal pouch 3 def: "An endoderm that is part of a thymus primordium." [OBOL:automatic] [Term] id: UBERON:0005563 ! trigeminal neural crest name: trigeminal neural crest def: "Cranial neural crest which gives rise to the trigeminal ganglion." [ZFA:0000080] comment: Editor note: todo - compare ZFA and EHDAA2 representation subset: vertebrate_core xref: ZFA:0000080 ! trigeminal neural crest xref: EHDAA2:0002083 ! trigeminal neural crest xref: EMAPA:16170 ! trigeminal neural crest xref: VHOG:0000269 ! trigeminal neural crest xref: EHDAA:667 ! trigeminal neural crest xref: EFO:0003484 ! trigeminal neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: part_of UBERON:0007213 {source="EHDAA2"} ! head mesenchyme from head neural crest xref: TAO:0000080 ! trigeminal neural crest property_value: homology_notes "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {external_class="VHOG:0000269", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005564 ! gonad primordium name: gonad primordium def: "Portion of tissue that gives rise to the immature gonad." [ZFA:0001262] comment: Taxon notes: this is a very broad grouping class subset: vertebrate_core subset: grouping_class synonym: "gonadal primordium" EXACT [ZFA:0001262] synonym: "undifferentiated gonad" EXACT [ZFA:0001262] xref: ZFA:0001262 ! gonad primordium xref: RETIRED_EHDAA2:0002148 ! gonad primordium xref: EHDAA:5927 ! gonad primordium xref: EMAPA:17204 ! gonad primordium xref: EFO:0003651 ! gonad primordium xref: WBbt:0008366 ! gonadal primordium is_a: UBERON:0000479 {source="ZFA"} ! tissue is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: part_of UBERON:0000990 {source="ZFA"} ! reproductive system relationship: develops_into UBERON:0000991 ! gonad xref: TAO:0001262 ! gonad primordium property_value: external_definition "Immature reproductive tissue that has not undergone final maturation into either testis or ovary.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001262", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005566 name: rhombomere 1 floor plate subset: vertebrate_core synonym: "floor plate r1" EXACT [ZFA:0000882] synonym: "floor plate rhombomere 1" EXACT [ZFA:0000882] xref: ZFA:0000882 ! floor plate rhombomere 1 xref: EHDAA2:0001640 ! rhombomere 1 floor plate xref: EMAPA:16291 ! floor plate of rhombomere 01 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16481 ! floor plate of rhombomere 01 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16919 ! floor plate of rhombomere 01 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17093 ! floor plate of rhombomere 01 of metencephalon (also: UBERON:0003310 'floor plate of metencephalon') xref: EFO:0003584 ! floor plate rhombomere 1 is_a: UBERON:0005500 ! rhombomere floor plate relationship: part_of UBERON:0005499 ! rhombomere 1 xref: TAO:0000882 ! floor plate rhombomere 1 [Term] id: UBERON:0005567 name: rhombomere 1 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 1" EXACT [ZFA:0000781] xref: ZFA:0000781 ! lateral wall rhombomere 1 xref: EHDAA2:0001641 ! rhombomere 1 lateral wall xref: EMAPA:16482 ! lateral wall of rhombomere 01 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16920 ! lateral wall of rhombomere 01 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17094 ! lateral wall of rhombomere 01 of metencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005499 ! rhombomere 1 xref: TAO:0000781 ! lateral wall rhombomere 1 def: "A rhombomere lateral wall that is part of a rhombomere 1." [OBOL:automatic] [Term] id: UBERON:0005568 name: rhombomere 1 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 1" EXACT [ZFA:0001033] xref: ZFA:0001033 ! roof plate rhombomere 1 xref: EHDAA2:0001645 ! rhombomere 1 roof plate xref: EMAPA:16483 ! roof plate of rhombomere 01 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16924 ! roof plate of rhombomere 01 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17098 ! roof plate of rhombomere 01 of metencephalon (also: UBERON:0003302 'roof plate of metencephalon') intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005499 ! rhombomere 1 xref: TAO:0001033 ! roof plate rhombomere 1 def: "A rhombomere roof plate that is part of a rhombomere 1." [OBOL:automatic] [Term] id: UBERON:0005569 ! rhombomere 2 name: rhombomere 2 subset: vertebrate_core synonym: "r2" EXACT [ZFA:0000822] xref: ZFA:0000822 ! rhombomere 2 xref: EHDAA2:0001647 ! rhombomere 2 xref: EMAPA:16293 ! rhombomere 02 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16484 ! rhombomere 02 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16925 ! rhombomere 02 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17099 ! rhombomere 02 of metencephalon xref: EFO:0003579 ! rhombomere 2 is_a: UBERON:0001892 ! rhombomere xref: XAO:0004080 ! rhombomere R2 relationship: develops_from UBERON:0007296 {evidence="definitional"} ! presumptive rhombomere 2 property_value: rhombomere_number "3" xsd:nonNegativeInteger xref: TAO:0000822 ! rhombomere 2 property_value: external_definition "Hindbrain segment or neuromere. Kimmel et al, 1995.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000822", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005570 name: rhombomere 2 floor plate subset: vertebrate_core synonym: "floor plate r2" EXACT [ZFA:0000763] synonym: "floorplate r2" EXACT [ZFA:0000763] synonym: "floor plate rhombomere 2" EXACT [ZFA:0000763] xref: ZFA:0000763 ! floor plate rhombomere 2 xref: EHDAA2:0001650 ! rhombomere 2 floor plate xref: EMAPA:16294 ! floor plate of rhombomere 02 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16485 ! floor plate of rhombomere 02 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16926 ! floor plate of rhombomere 02 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17100 ! floor plate of rhombomere 02 of metencephalon (also: UBERON:0003310 'floor plate of metencephalon') xref: EFO:0003568 ! floor plate rhombomere 2 intersection_of: UBERON:0005500 ! rhombomere floor plate intersection_of: part_of UBERON:0005569 ! rhombomere 2 xref: TAO:0000763 ! floor plate rhombomere 2 def: "A rhombomere floor plate that is part of a rhombomere 2." [OBOL:automatic] [Term] id: UBERON:0005571 name: rhombomere 2 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 2" EXACT [ZFA:0000907] xref: ZFA:0000907 ! lateral wall rhombomere 2 xref: EHDAA2:0001651 ! rhombomere 2 lateral wall xref: EMAPA:16486 ! lateral wall of rhombomere 02 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16927 ! lateral wall of rhombomere 02 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17101 ! lateral wall of rhombomere 02 of metencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005569 ! rhombomere 2 xref: TAO:0000907 ! lateral wall rhombomere 2 def: "A rhombomere lateral wall that is part of a rhombomere 2." [OBOL:automatic] [Term] id: UBERON:0005572 name: rhombomere 2 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 2" EXACT [ZFA:0000824] xref: ZFA:0000824 ! roof plate rhombomere 2 xref: EHDAA2:0001655 ! rhombomere 2 roof plate xref: EMAPA:16487 ! roof plate of rhombomere 02 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16931 ! roof plate of rhombomere 02 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17105 ! roof plate of rhombomere 02 of metencephalon (also: UBERON:0003302 'roof plate of metencephalon') intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005569 ! rhombomere 2 xref: TAO:0000824 ! roof plate rhombomere 2 def: "A rhombomere roof plate that is part of a rhombomere 2." [OBOL:automatic] [Term] id: UBERON:0005573 name: rhombomere 3 floor plate subset: vertebrate_core synonym: "floor plate r3" EXACT [ZFA:0000888] synonym: "floorplate r3" EXACT [ZFA:0000888] synonym: "floor plate rhombomere 3" EXACT [ZFA:0000888] xref: ZFA:0000888 ! floor plate rhombomere 3 xref: EHDAA2:0001660 ! rhombomere 3 floor plate xref: EMAPA:16298 ! floor plate of rhombomere 03 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16489 ! floor plate of rhombomere 03 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16933 ! floor plate of rhombomere 03 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17107 ! floor plate of rhombomere 03 of myelencephalon xref: EFO:0003586 ! floor plate rhombomere 3 intersection_of: UBERON:0005500 ! rhombomere floor plate intersection_of: part_of UBERON:0005507 ! rhombomere 3 xref: TAO:0000888 ! floor plate rhombomere 3 def: "A rhombomere floor plate that is part of a rhombomere 3." [OBOL:automatic] [Term] id: UBERON:0005574 name: rhombomere 3 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 3" EXACT [ZFA:0000994] xref: ZFA:0000994 ! lateral wall rhombomere 3 xref: EHDAA2:0001661 ! rhombomere 3 lateral wall xref: EMAPA:16490 ! lateral wall of rhombomere 03 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16934 ! lateral wall of rhombomere 03 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17108 ! lateral wall of rhombomere 03 of myelencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005507 ! rhombomere 3 xref: TAO:0000994 ! lateral wall rhombomere 3 def: "A rhombomere lateral wall that is part of a rhombomere 3." [OBOL:automatic] [Term] id: UBERON:0005575 name: rhombomere 3 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 3" EXACT [ZFA:0000950] xref: ZFA:0000950 ! roof plate rhombomere 3 xref: EHDAA2:0001665 ! rhombomere 3 roof plate xref: EMAPA:16491 ! roof plate of rhombomere 03 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16938 ! roof plate of rhombomere 03 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17112 ! roof plate of rhombomere 03 of myelencephalon intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005507 ! rhombomere 3 xref: TAO:0000950 ! roof plate rhombomere 3 def: "A rhombomere roof plate that is part of a rhombomere 3." [OBOL:automatic] [Term] id: UBERON:0005576 name: rhombomere 4 floor plate subset: vertebrate_core synonym: "floor plate r4" EXACT [ZFA:0000893] synonym: "floorplate r4" EXACT [ZFA:0000893] synonym: "floor plate rhombomere 4" EXACT [ZFA:0000893] xref: ZFA:0000893 ! floor plate rhombomere 4 xref: EHDAA2:0001670 ! rhombomere 4 floor plate xref: EMAPA:16302 ! floor plate of rhombomere 04 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16493 ! floor plate of rhombomere 04 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16940 ! floor plate of rhombomere 04 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17114 ! floor plate of rhombomere 04 of myelencephalon xref: EFO:0003588 ! floor plate rhombomere 4 intersection_of: UBERON:0005500 ! rhombomere floor plate intersection_of: part_of UBERON:0005511 ! rhombomere 4 xref: TAO:0000893 ! floor plate rhombomere 4 def: "A rhombomere floor plate that is part of a rhombomere 4." [OBOL:automatic] [Term] id: UBERON:0005577 name: rhombomere 4 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 4" EXACT [ZFA:0000782] xref: ZFA:0000782 ! lateral wall rhombomere 4 xref: EHDAA2:0001671 ! rhombomere 4 lateral wall xref: EMAPA:16494 ! lateral wall of rhombomere 04 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16941 ! lateral wall of rhombomere 04 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17115 ! lateral wall of rhombomere 04 of myelencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005511 ! rhombomere 4 xref: TAO:0000782 ! lateral wall rhombomere 4 def: "A rhombomere lateral wall that is part of a rhombomere 4." [OBOL:automatic] [Term] id: UBERON:0005578 name: rhombomere 4 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 4" EXACT [ZFA:0001034] xref: ZFA:0001034 ! roof plate rhombomere 4 xref: EHDAA2:0001675 ! rhombomere 4 roof plate xref: EMAPA:16495 ! roof plate of rhombomere 04 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16945 ! roof plate of rhombomere 04 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17119 ! roof plate of rhombomere 04 of myelencephalon intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005511 ! rhombomere 4 xref: TAO:0001034 ! roof plate rhombomere 4 def: "A rhombomere roof plate that is part of a rhombomere 4." [OBOL:automatic] [Term] id: UBERON:0005579 name: rhombomere 5 floor plate subset: vertebrate_core synonym: "floor plate r5" EXACT [ZFA:0000764] synonym: "floorplate r5" EXACT [ZFA:0000764] synonym: "floor plate rhombomere 5" EXACT [ZFA:0000764] xref: ZFA:0000764 ! floor plate rhombomere 5 xref: EHDAA2:0001680 ! rhombomere 5 floor plate xref: EMAPA:16306 ! floor plate of rhombomere 05 of future rhombencephalon of future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16497 ! floor plate of rhombomere 05 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16947 ! floor plate of rhombomere 05 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17121 ! floor plate of rhombomere 05 of myelencephalon xref: EFO:0003569 ! floor plate rhombomere 5 intersection_of: UBERON:0005500 ! rhombomere floor plate intersection_of: part_of UBERON:0005515 ! rhombomere 5 xref: TAO:0000764 ! floor plate rhombomere 5 def: "A rhombomere floor plate that is part of a rhombomere 5." [OBOL:automatic] [Term] id: UBERON:0005580 name: rhombomere 5 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 5" EXACT [ZFA:0000908] xref: ZFA:0000908 ! lateral wall rhombomere 5 xref: EHDAA2:0001681 ! rhombomere 5 lateral wall xref: EMAPA:16498 ! lateral wall of rhombomere 05 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16948 ! lateral wall of rhombomere 05 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17122 ! lateral wall of rhombomere 05 of myelencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005515 ! rhombomere 5 xref: TAO:0000908 ! lateral wall rhombomere 5 def: "A rhombomere lateral wall that is part of a rhombomere 5." [OBOL:automatic] [Term] id: UBERON:0005581 name: rhombomere 5 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 5" EXACT [ZFA:0000828] xref: ZFA:0000828 ! roof plate rhombomere 5 xref: EHDAA2:0001685 ! rhombomere 5 roof plate xref: EMAPA:16499 ! roof plate of rhombomere 05 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16952 ! roof plate of rhombomere 05 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17126 ! roof plate of rhombomere 05 of myelencephalon intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005515 ! rhombomere 5 xref: TAO:0000828 ! roof plate rhombomere 5 def: "A rhombomere roof plate that is part of a rhombomere 5." [OBOL:automatic] [Term] id: UBERON:0005582 name: rhombomere 6 floor plate subset: vertebrate_core synonym: "floor plate r6" EXACT [ZFA:0000889] synonym: "floorplate r6" EXACT [ZFA:0000889] synonym: "floor plate rhombomere 6" EXACT [ZFA:0000889] xref: ZFA:0000889 ! floor plate rhombomere 6 xref: EHDAA2:0001690 ! rhombomere 6 floor plate xref: EMAPA:16501 ! floor plate of rhombomere 06 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16954 ! floor plate of rhombomere 06 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17128 ! floor plate of rhombomere 06 of myelencephalon xref: EFO:0003587 ! floor plate rhombomere 6 intersection_of: UBERON:0005500 ! rhombomere floor plate intersection_of: part_of UBERON:0005519 ! rhombomere 6 xref: TAO:0000889 ! floor plate rhombomere 6 def: "A rhombomere floor plate that is part of a rhombomere 6." [OBOL:automatic] [Term] id: UBERON:0005583 name: rhombomere 6 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 6" EXACT [ZFA:0000995] xref: ZFA:0000995 ! lateral wall rhombomere 6 xref: EHDAA2:0001691 ! rhombomere 6 lateral wall xref: EMAPA:16502 ! lateral wall of rhombomere 06 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16955 ! lateral wall of rhombomere 06 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17129 ! lateral wall of rhombomere 06 of myelencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005519 ! rhombomere 6 xref: TAO:0000995 ! lateral wall rhombomere 6 def: "A rhombomere lateral wall that is part of a rhombomere 6." [OBOL:automatic] [Term] id: UBERON:0005584 name: rhombomere 6 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 6" EXACT [ZFA:0000825] xref: ZFA:0000825 ! roof plate rhombomere 6 xref: EHDAA2:0001695 ! rhombomere 6 roof plate xref: EMAPA:16503 ! roof plate of rhombomere 06 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16959 ! roof plate of rhombomere 06 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17133 ! roof plate of rhombomere 06 of myelencephalon intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005519 ! rhombomere 6 xref: TAO:0000825 ! roof plate rhombomere 6 def: "A rhombomere roof plate that is part of a rhombomere 6." [OBOL:automatic] [Term] id: UBERON:0005585 name: rhombomere 7 floor plate subset: vertebrate_core synonym: "floor plate r7" EXACT [ZFA:0000904] synonym: "floorplate r7" EXACT [ZFA:0000904] synonym: "floor plate rhombomere 7" EXACT [ZFA:0000904] xref: ZFA:0000904 ! floor plate rhombomere 7 xref: EHDAA2:0001700 ! rhombomere 7 floor plate xref: EMAPA:16505 ! floor plate of rhombomere 07 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16961 ! floor plate of rhombomere 07 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17135 ! floor plate of rhombomere 07 of myelencephalon xref: EFO:0003589 ! floor plate rhombomere 7 intersection_of: UBERON:0005500 ! rhombomere floor plate intersection_of: part_of UBERON:0005523 ! rhombomere 7 xref: TAO:0000904 ! floor plate rhombomere 7 def: "A rhombomere floor plate that is part of a rhombomere 7." [OBOL:automatic] [Term] id: UBERON:0005586 name: rhombomere 7 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 7" EXACT [ZFA:0000783] xref: ZFA:0000783 ! lateral wall rhombomere 7 xref: EHDAA2:0001701 ! rhombomere 7 lateral wall xref: EMAPA:16506 ! lateral wall of rhombomere 07 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16962 ! lateral wall of rhombomere 07 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17136 ! lateral wall of rhombomere 07 of myelencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005523 ! rhombomere 7 xref: TAO:0000783 ! lateral wall rhombomere 7 def: "A rhombomere lateral wall that is part of a rhombomere 7." [OBOL:automatic] [Term] id: UBERON:0005587 name: rhombomere 7 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 7" EXACT [ZFA:0000951] xref: ZFA:0000951 ! roof plate rhombomere 7 xref: EHDAA2:0001705 ! rhombomere 7 roof plate xref: EMAPA:16507 ! roof plate of rhombomere 07 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16966 ! roof plate of rhombomere 07 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17140 ! roof plate of rhombomere 07 of myelencephalon intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005523 ! rhombomere 7 xref: TAO:0000951 ! roof plate rhombomere 7 def: "A rhombomere roof plate that is part of a rhombomere 7." [OBOL:automatic] [Term] id: UBERON:0005588 name: rhombomere 8 floor plate subset: vertebrate_core synonym: "floor plate r8" EXACT [ZFA:0000765] synonym: "floorplate r8" EXACT [ZFA:0000765] synonym: "floor plate rhombomere 8" EXACT [ZFA:0000765] xref: ZFA:0000765 ! floor plate rhombomere 8 xref: EHDAA2:0001709 ! rhombomere 8 floor plate xref: EMAPA:16509 ! floor plate of rhombomere 08 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16968 ! floor plate of rhombomere 08 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17142 ! floor plate of rhombomere 08 of myelencephalon xref: EFO:0003570 ! floor plate rhombomere 8 intersection_of: UBERON:0005500 ! rhombomere floor plate intersection_of: part_of UBERON:0005527 ! rhombomere 8 xref: TAO:0000765 ! floor plate rhombomere 8 def: "A rhombomere floor plate that is part of a rhombomere 8." [OBOL:automatic] [Term] id: UBERON:0005589 name: rhombomere 8 lateral wall subset: vertebrate_core synonym: "lateral wall rhombomere 8" EXACT [ZFA:0000909] xref: ZFA:0000909 ! lateral wall rhombomere 8 xref: EHDAA2:0001710 ! rhombomere 8 lateral wall xref: EMAPA:16510 ! lateral wall of rhombomere 08 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16969 ! lateral wall of rhombomere 08 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17143 ! lateral wall of rhombomere 08 of myelencephalon intersection_of: UBERON:0005501 ! rhombomere lateral wall intersection_of: part_of UBERON:0005527 ! rhombomere 8 xref: TAO:0000909 ! lateral wall rhombomere 8 def: "A rhombomere lateral wall that is part of a rhombomere 8." [OBOL:automatic] [Term] id: UBERON:0005590 name: rhombomere 8 roof plate subset: vertebrate_core synonym: "roof plate rhombomere 8" EXACT [ZFA:0001035] xref: ZFA:0001035 ! roof plate rhombomere 8 xref: EHDAA2:0001714 ! rhombomere 8 roof plate xref: EMAPA:16511 ! roof plate of rhombomere 08 of future rhombencephalon of future brain of central nervous system of nervous system of organ system xref: EMAPA:16973 ! roof plate of rhombomere 08 of hindbrain of brain of central nervous system of nervous system of organ system xref: EMAPA:17147 ! roof plate of rhombomere 08 of myelencephalon intersection_of: UBERON:0005502 ! rhombomere roof plate intersection_of: part_of UBERON:0005527 ! rhombomere 8 xref: TAO:0001035 ! roof plate rhombomere 8 def: "A rhombomere roof plate that is part of a rhombomere 8." [OBOL:automatic] [Term] id: UBERON:0012172 name: stomach primordium is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: part_of UBERON:0003258 ! endoderm of foregut xref: ncithesaurus:Stomach_Primordium ! stomach primordium xref: EFO:0002580 ! stomach endoderm synonym: "stomach endoderm" RELATED [EFO:0002580] xref: UMLS:C1514976 [Term] id: UBERON:0008947 ! respiratory primordium name: respiratory primordium is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: part_of UBERON:0003258 ! endoderm of foregut xref: EHDAA2:0004069 ! respiratory primordium xref: ncithesaurus:Respiratory_Primordium ! Respiratory Primordium xref: UMLS:C1514898 [Term] id: UBERON:0005597 ! lung primordium name: lung primordium def: "A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum." [XAO:0001002] synonym: "lateral diverticula" RELATED [XAO:0001002] synonym: "lung endoderm" RELATED [EFO:0002578] xref: XAO:0001002 ! lung primordium is_a: UBERON:0001048 {source="XAO"} ! primordium relationship: develops_from UBERON:0001041 {source="XAO"} ! foregut relationship: part_of UBERON:0008947 ! respiratory primordium xref: AAO:0011059 ! lung primordium xref: EFO:0002578 ! lung endoderm [Term] id: UBERON:0000118 name: lung bud def: "Structure derived from foregut that becomes a lung[GO]." [GO:0060431, Wikipedia:Respiratory_bud] comment: Editors note: clarify successors - include bronchi? synonym: "primary lung bud" RELATED [GO:0060572] synonym: "lung bud" RELATED PLURAL [] synonym: "respiratory diverticulum" RELATED [Wikipedia:Lung_buds] synonym: "gemma respiratoria" RELATED LATIN [Wikipedia:Lung_buds] synonym: "gemma pulmonalis" RELATED LATIN [Wikipedia:Lung_buds] xref: BTO:0001643 ! lung bud xref: http://upload.wikimedia.org/wikipedia/commons/thumb/7/71/Gray948.png/200px-Gray948.png is_a: UBERON:0005153 {source="GO:0060441"} ! epithelial bud relationship: develops_from UBERON:0005597 ! lung primordium relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium relationship: adjacent_to UBERON:0004872 ! splanchnic layer of lateral plate mesoderm xref: EHDAA2:0004089 ! lung bud xref: SCTID:361427007 ! Lung bud xref: ncithesaurus:Respiratory_Diverticulum ! Respiratory Diverticulum xref: ncithesaurus:Primary_Bronchial_Bud ! primary bronchial bud xref: UMLS:C1514420 xref: UMLS:C1514897 [Term] id: UBERON:0012925 name: bronchial bud xref: BTO:0001641 ! bronchial bud is_a: UBERON:0005153 {source="GO:0060441"} ! epithelial bud relationship: develops_from UBERON:0005597 ! lung primordium [Term] id: UBERON:0005594 name: head somite def: "Somite located in the head region, caudal to the otic vesicle" [PMID:11830559] comment: Development notes: They provide the epaxial and hypaxial muscles of the neck, the pharyngeal and laryngeal muscles that develop in the caudal branchial arches and the musculature of the tongue. Despite their localisation in the head, myogenic precursors from occipital somites essentially follow the trunk programmes (E. H. Walters and S. D., unpublished). during evolution, have been secondarily incorporated into the head (Gans and Northcutt, 1983)[PMID:11830559]. AO notes: EHDAA2 has both 'head somite' and 'head somite group', with part_of and develops_from for latter. Taxon notes: in humans this includes somites 1-4 synonym: "cranial somite" RELATED [XAO:0000313] synonym: "occipital somite" EXACT [XAO:0000313, PMID:11830559] xref: XAO:0000313 ! head somite xref: EHDAA2:0003437 ! head somite xref: EMAPA:16172 ! somite intersection_of: UBERON:0002329 ! somite intersection_of: develops_from UBERON:0009617 ! head paraxial mesoderm relationship: part_of UBERON:0009617 {source="EHDAA2"} ! head paraxial mesoderm relationship: develops_from UBERON:0009617 {source="EHDAA2"} ! head paraxial mesoderm [Term] id: UBERON:0005598 name: trunk somite xref: XAO:0000314 ! trunk somite xref: EHDAA2:0003438 ! trunk somite intersection_of: UBERON:0002329 ! somite intersection_of: part_of UBERON:0002100 ! trunk xref: AAO:0010385 ! trunk somite xref: EMAPA:16184 ! somite def: "A somite that is part of a trunk." [OBOL:automatic] [Term] id: UBERON:0009621 name: tail somite intersection_of: UBERON:0002329 ! somite intersection_of: part_of UBERON:0002415 ! tail xref: AAO:0010383 ! tail somite xref: XAO:0003143 ! tail somite xref: EMAPA:16860 ! somite def: "A somite that is part of a tail." [OBOL:automatic] [Term] id: UBERON:0005599 name: common dorsal aorta xref: MA:0000477 ! common dorsal aorta xref: EHDAA2:0000307 ! common dorsal aorta xref: EMAPA:16327 ! common of dorsal aorta of arterial system of cardiovascular system of organ system xref: EHDAA:1251 ! common of dorsal aorta is_a: UBERON:0000947 ! aorta relationship: part_of UBERON:0005805 ! dorsal aorta [Term] id: UBERON:0005600 name: crus commune synonym: "crus commune" RELATED [MA:0001210] xref: MA:0001210 ! crus commune xref: EHDAA2:0000330 ! crus commune xref: EMAPA:17818 ! crus commune xref: VHOG:0001344 ! crus commune xref: EHDAA:7783 ! crus commune is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001856 ! semicircular duct xref: SCTID:279758009 ! Crus commune [Term] id: UBERON:0005606 ! hyaloid cavity name: hyaloid cavity xref: MA:0000272 ! hyaloid cavity xref: EHDAA2:0000789 ! hyaloid cavity xref: EMAPA:17302 ! hyaloid cavity xref: VHOG:0001477 ! hyaloid cavity xref: EHDAA:4733 ! hyaloid cavity is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0002203 ! vasculature of eye relationship: has_quality PATO:0000608 ! closed property_value: external_definition "A depression in the front of the vitreous body, lodging the lens. [adapted_from_the_definition_of_the_hyaloid_fossa]" xsd:string {ontology="VHOG", external_class="VHOG:0001477", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/hyaloid+fossa", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005492 ! hyaloid vessel name: hyaloid vessel def: "blood vessel of transient vascular system of the eye during development, that normally nourishes the retina, immature lens and primary vitreous of the developing eye." [MP:0001289] comment: note we are currently conflating vessel and vasculature - we may wish to split this class - see also vascular plexus term subset: vertebrate_core synonym: "hyaloid vascular system" RELATED [MP:0001289] synonym: "hyaloid vasculature" RELATED [ZFA:0005046] synonym: "hyaloid capillary system" RELATED [MP:0001289] xref: ZFA:0005046 ! hyaloid vessel xref: VHOG:0000232 ! hyaloid vessels xref: EHDAA:4735 ! hyaloid vessels is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0001981 ! blood vessel relationship: part_of UBERON:0002203 {source="ZFA-modified"} ! vasculature of eye xref: XAO:0004154 ! hyaloid blood vessel xref: TAO:0005046 ! hyaloid vessel synonym: "hyaloid vessels" EXACT PLURAL [TAO:0005046] [Term] id: UBERON:0006011 name: hyaloid vein synonym: "hyaloid veins" EXACT PLURAL [ZFA:0005047] xref: ZFA:0005047 ! hyaloid vein xref: EHDAA2:0000791 ! hyaloid vein is_a: UBERON:0001638 ! vein is_a: UBERON:0005492 ! hyaloid vessel relationship: develops_from UBERON:0011191 {source="EHDAA2"} ! ophthalmic vein xref: XAO:0004156 ! hyaloid vein xref: TAO:0005047 ! hyaloid vein property_value: external_definition "Vein internal to the eye. Isogai et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005047", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0002270 name: hyaloid artery def: "The hyaloid artery is a branch of the ophthalmic artery, which is itself a branch of the internal carotid artery. It is contained within the optic stalk of the eye and extends from the optic disc through the vitreous humor to the lens. Usually fully regressed before birth, its purpose is to supply nutrient to the developing lens in the growing fetus. During the tenth week of development in humans (time varies depending on species), the lens grows independent of a blood supply and the hyaloid artery usually regresses. Its proximal portion remains as the central artery of the retina. Regression of the hyaloid artery leaves a clear central zone through the vitreous called the hyaloid canal or Cloquet's canal. Cloquet's canal is named after the man who first described it, French physician Jules Germain Cloquet (1790b1883). Occasionally the artery may not fully regress, resulting in the condition persistent hyaloid artery. More commonly, small remnants of the artery may remain. Free remnants can sometimes be seen as \"floaters\". An anterior remnant of the hyaloid artery can be seen in some people as Mittendorf's dot, a small pinpoint-like scar on the posterior surface of the lens. A posterior remnant may be seen where the artery left the optic disc, and is known as Bergmeister's papilla." [Wikipedia:Hyaloid_artery] comment: ZFA def is: Artery that is internal to the eye; this is more general than the human-centric definition here.. subset: uberon_slim subset: vertebrate_core synonym: "Cloquets canal" RELATED [Wikipedia:Hyaloid_artery] synonym: "Cloquet's canal" RELATED [Wikipedia:Hyaloid_artery] synonym: "central artery of retina" RELATED [EMAPA:19242] xref: FMA:77670 ! Hyaloid artery xref: TAO:0005045 ! hyaloid artery xref: ZFA:0005045 ! hyaloid artery xref: VHOG:0001478 ! hyaloid artery xref: EMAPA:19242 ! hyaloid artery xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Schematic_diagram_of_the_human_eye_en.svg/200px-Schematic_diagram_of_the_human_eye_en.svg.png is_a: UBERON:0001637 {source="ZFA"} ! artery relationship: part_of UBERON:0005492 {source="ZFA"} ! hyaloid vessel relationship: part_of UBERON:0003098 {source="Wikipedia"} ! optic stalk relationship: develops_into UBERON:0006010 ! hyaloid canal xref: EHDAA2:0004072 ! hyaloid artery xref: SCTID:308790003 ! Entire hyaloid artery xref: XAO:0004155 ! hyaloid artery synonym: "arteria hyaloidea" RELATED LATIN [Wikipedia:Hyaloid_artery] xref: http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg property_value: external_definition "Artery that is internal to the eye. Isogai et al. 2001.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005045", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0006010 ! hyaloid canal name: hyaloid canal def: "Hyaloid canal is a small transparent canal running through the vitreous body from the optical nerve disc to the lens; in foetus it contains a prolongation of the central artery of the retina, the hyaloid artery. Other names: Cloquet's canal, Stilling's canal. The function of the canal is to provide an adjustable reservoir of mobile liquid which may be easily and rapidly displaced backwards in positive accommodation, forwards in negative accommodation[WP]. a passage running from in front of the optic disk to the lens of the eye; in the fetus, it transmits the hyaloid artery[TFD]." [Wikipedia:Hyaloid_canal, http://medical-dictionary.thefreedictionary.com/Hyaloid+canal] comment: in FMA, this is_a FMA:67388 portion of vitreous humor synonym: "canal of Cloquet" EXACT [FMA:58837] synonym: "Cloquet's canal" EXACT [FMA:58837] synonym: "Stilling's canal" EXACT [FMA:58837] xref: FMA:58837 ! hyaloid canal is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0001798 ! vitreous body relationship: develops_from UBERON:0002270 {source="Wikipedia"} ! hyaloid artery xref: SCTID:362506002 ! Entire hyaloid canal xref: http://upload.wikimedia.org/wikipedia/commons/e/eb/Gray869.png [Term] id: UBERON:0005607 name: hyaloid vascular plexus synonym: "hyaloid vascular system" RELATED [] xref: MA:0001283 ! hyaloid vascular plexus xref: EHDAA2:0000790 ! hyaloid vascular plexus xref: EMAPA:17303 ! hyaloid vascular plexus xref: VHOG:0000442 ! hyaloid vascular plexus xref: EHDAA:5703 ! hyaloid vascular plexus is_a: UBERON:0005629 ! vascular plexus relationship: located_in UBERON:0005606 ! hyaloid cavity relationship: part_of UBERON:0009141 {source="EHDAA2"} ! craniocervical region vein xref: XAO:0004157 ! hyaloid vascular plexus [Term] id: UBERON:0006358 name: vasa hyaloidea propria def: "The vasa hyaloidea propria and tunica vasculosa lentis are small branches of the hyaloid artery which fill the primary vitreous" [] xref: MA:0001285 ! vasa hyaloidea propria xref: EMAPA:18236 ! vasa hyaloidea propria is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0005607 {source="EMAPA"} ! hyaloid vascular plexus [Term] id: UBERON:0006305 name: tunica vasculosa lentis def: "an extensive capillary network, spreading over the posterior and lateral surfaces of the lens of the eye. It disappears shortly after birth." [Wikipedia:Tunica_vasculosa_lentis] subset: emapa_ehdaa2 xref: EMAPA:18235 ! tunica vasculosa lentis xref: EHDAA2:0002097 ! tunica vasculosa lentis xref: VHOG:0000978 ! tunica vasculosa lentis xref: EHDAA:5705 ! tunica vasculosa lentis is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0005607 ! hyaloid vascular plexus property_value: homology_notes "Soon after it forms, the mammalian lens becomes invested with a network of capillaries. (...) The capillary network on the posterior of the lens is the tunica vasculosa lentis (TVL).[well established][VHOG]" xsd:string {external_class="VHOG:0000978", ontology="VHOG", source="DOI:10.1016/j.semcdb.2007.08.014 Beebe DC\, Maintening transparency: A review of the developmental physiology and pathophysiology of two avascular tissues. Seminars in Cell and Developmental Biology (2008) Fig.1", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005628 ! ileal artery name: ileal artery def: "The ileal arteries feed oxygenated blood into the ileum, a portion of the small intestine in mammals, reptiles, and birds. They are branches of the superior mesenteric artery." [Wikipedia:Ileal_arteries] synonym: "ileal branch of superior mesenteric artery" EXACT [FMA:14809] xref: FMA:14809 ! Ileal artery is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0001182 ! superior mesenteric artery relationship: part_of UBERON:0001182 ! superior mesenteric artery xref: galen:IlealArteries xref: SCTID:265479003 ! Entire ileal artery synonym: "arteriae ileales" RELATED LATIN [Wikipedia:Ileal_arteries] xref: http://upload.wikimedia.org/wikipedia/commons/8/86/Gray535.png [Term] id: UBERON:0005610 name: iliac vein xref: MA:0002142 ! iliac vein xref: EHDAA2:0000811 ! iliac vein xref: MESH:A07.231.908.427 ! iliac vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0002355 ! pelvis xref: ncithesaurus:Iliac_Vein ! Iliac Vein xref: UMLS:C0020888 [Term] id: UBERON:0006742 ! canthus name: canthus def: "Canthus (pl. canthi, palpebral commissures) is either corner of the eye where the upper and lower eyelids meet. The bicanthal plane is the transversal plane linking both canthi and defines the upper boundary of the midface." [Wikipedia:Canthus] synonym: "bicanthal" RELATED [Wikipedia:Canthus] synonym: "bicanthal plane" RELATED [Wikipedia:Canthus] synonym: "canthi" RELATED [Wikipedia:Canthus] synonym: "canthoplasty" RELATED [Wikipedia:Canthus] synonym: "canthorum" RELATED [Wikipedia:Canthus] synonym: "canthus %28anatomy%29" RELATED [Wikipedia:Canthus] synonym: "palpebral commissure" EXACT [FMA:59222] xref: FMA:59222 ! Palpebral commissure is_a: UBERON:0000061 ! anatomical structure relationship: adjacent_to UBERON:0001713 ! lower eyelid relationship: adjacent_to UBERON:0001712 ! upper eyelid xref: SCTID:181145006 ! Entire canthus xref: http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray892.png [Term] id: UBERON:0005611 name: inner canthus synonym: "nasal canthus" RELATED [] synonym: "medial canthus" RELATED [MA:0001262] synonym: "medial canthus of eye" RELATED [] synonym: "medial palpebral commissure" EXACT [FMA:59316] xref: MA:0001262 ! inner canthus xref: EHDAA2:0000829 ! inner canthus xref: FMA:59316 ! Medial palpebral commissure xref: EMAPA:17830 ! inner canthus xref: VHOG:0000829 ! inner canthus is_a: UBERON:0006742 ! canthus xref: ncithesaurus:Inner_Canthus ! Inner Canthus xref: SCTID:362526003 ! Entire medial canthus property_value: external_definition "The angle at the end of the palpebral fissure, the slit between the eyelids, close to the nose. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, adapted_from_Kaufman_MH_and_Bard_JBL, p.263][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000829", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C1708516 [Term] id: UBERON:0006726 name: outer canthus comment: see also FMA:59321 ! Lateral angle of eye synonym: "temporal canthus" RELATED [] synonym: "lateral canthus" RELATED [MA:0001264] synonym: "lateral canthus of eye" EXACT [FMA:59321] synonym: "lateral angle of eye" RELATED [FMA:59321] synonym: "lateral palpebral commissure" EXACT [FMA:59315] xref: FMA:59315 ! Lateral palpebral commissure xref: MA:0001264 ! outer canthus xref: EHDAA2:0000910 ! lateral canthus xref: EHDAA:9039 ! lateral canthus is_a: UBERON:0006742 ! canthus xref: ncithesaurus:Outer_Canthus ! Outer Canthus xref: SCTID:362525004 ! Entire lateral canthus xref: VHOG:0001571 ! outer canthus property_value: external_definition "The angle at the end of the palpebral fissure, the slit between the eyelids, close to the temporal region of the skull. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, adapted_from_Kaufman_MH_and_Bard_JBL, p.263][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001571", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C1711189 [Term] id: UBERON:0005612 ! intercostal artery name: intercostal artery def: "One of a group of arteries that supply the area between the ribs ('costae'), called the intercostal space." [Wikiepdia:Intercostal_arteries] comment: TODO - add children xref: MA:0001981 ! intercostal artery xref: EHDAA2:0000840 ! intercostal artery xref: EMAPA:18753 ! intercostal artery xref: EHDAA:5307 ! intercostal artery is_a: UBERON:0001637 ! artery xref: ncithesaurus:Intercostal_Artery ! Intercostal Artery xref: SCTID:281134007 ! Intercostal artery xref: UMLS:C0459917 [Term] id: UBERON:0005621 name: rhomboid def: "A rhombus-shaped muscle associated with the scapula and chiefly responsible for its retraction. There are two rhomboid muscles." [Wikipedia:Rhomboid_muscles] synonym: "rhomboid muscle" EXACT [] comment: TODO - add child terms xref: MA:0002367 ! rhomboid xref: EHDAA2:0001635 ! rhomboid xref: VHOG:0001391 ! rhomboid muscle xref: EHDAA:8315 ! rhomboid is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle relationship: develops_from UBERON:0010985 {source="EHDAA2"} ! rhomboid pre-muscle mass xref: SCTID:277441005 ! Rhomboid xref: EHDAA2:0001635 ! rhomboid relationship: has_muscle_antagonist UBERON:0001125 {source="dbpedia"} ! serratus anterior synonym: "musculus rhomboideus" RELATED LATIN [Wikipedia:Rhomboid_muscles] relationship: has_muscle_origin UBERON:0000351 {source="dbpedia", notes="nuchal ligaments spinous processes of the C7 to T5 vertebrae"} ! nuchal ligament relationship: has_muscle_origin UBERON:0001076 {source="dbpedia", notes="nuchal ligaments spinous processes of the C7 to T5 vertebrae"} ! spinous process of vertebra xref: http://upload.wikimedia.org/wikipedia/commons/a/aa/Rhomboidei.PNG synonym: "rhomboideus" RELATED [VHOG:0001391] [Term] id: UBERON:0010985 name: rhomboid pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle xref: EHDAA2:0001636 ! rhomboid pre-muscle mass [Term] id: UBERON:0005623 name: semi-lunar valve synonym: "semilunar valve" EXACT [MA:0002790] synonym: "semilunar valves" EXACT PLURAL [MA:0002790] xref: MA:0002790 ! semilunar valve xref: EHDAA2:0001823 ! semi-lunar valves xref: VHOG:0001393 ! semilunar valve xref: EHDAA:4408 ! semi-lunar valves is_a: UBERON:0000946 ! cardial valve property_value: homology_notes "Extensive conservation of valve developmental mechanisms also has been observed among vertebrate species including chicken, mouse, and human.[well established][VHOG]" xsd:string {external_class="VHOG:0001393", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0005624 name: suprarenal artery def: "Artery that supplies blood to the adrenal glands." [Wikipedia:Adrenal_artery] synonym: "adrenal artery" RELATED [MA:0001914, Wikipedia:Adrenal_artery] subset: grouping_class xref: MA:0001914 ! suprarenal artery xref: EHDAA2:0001965 ! suprarenal artery xref: EHDAA:8596 ! suprarenal artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002369 ! adrenal gland xref: ncithesaurus:Adrenal_Artery ! Adrenal Artery xref: ncithesaurus:Suprarenal_Artery ! Suprarenal Artery xref: SCTID:181342004 ! Entire adrenal artery [Term] id: UBERON:0012173 name: middle suprarenal artery def: "The middle suprarenal arteries (middle capsular arteries; suprarenal arteries) are two small vessels which arise, one from either side of the abdominal aorta, opposite the superior mesenteric artery. They pass laterally and slightly upward, over the crura of the diaphragm, to the suprarenal glands, where they anastomose with suprarenal branches of the inferior phrenic and renal arteries. In the fetus these arteries are of large size." [Wikipedia:Middle_suprarenal_arteries] synonym: "middle suprarenal" RELATED [Wikipedia:Middle_suprarenal_arteries] synonym: "middle suprarenal artery" RELATED [Wikipedia:Middle_suprarenal_arteries] synonym: "middle capsular artery" RELATED [Wikipedia:Middle_suprarenal_arteries] synonym: "arteria suprarenalis media" RELATED LATIN [Wikipedia:Middle_suprarenal_arteries] synonym: "middle suprarenal arterial tree" EXACT [FMA:14754] is_a: UBERON:0005624 ! suprarenal artery relationship: branch_of UBERON:0001516 {source="Wikipedia"} ! abdominal aorta xref: FMA:14754 ! middle suprarenal artery xref: SCTID:303425000 ! Entire middle suprarenal artery [Term] id: UBERON:0005636 name: caecum epithelium xref: EHDAA2:0000209 ! caecum epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001153 ! cecum def: "An epithelium that is part of a caecum." [OBOL:automatic] [Term] id: UBERON:0005637 name: pyloric region epithelium xref: EHDAA2:0001582 ! pyloric region epithelium xref: RETIRED_EHDAA2:0001927 ! stomach pyloric region epithelium xref: EMAPA:17633 ! epithelium of pyloric region of stomach of foregut intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001166 ! pylorus def: "An epithelium that is part of a pylorus." [OBOL:automatic] [Term] id: UBERON:0005638 name: anterior chamber epithelium xref: EHDAA2:0000130 ! anterior chamber epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001766 ! anterior chamber of eyeball def: "An epithelium that is part of a anterior chamber of eyeball." [OBOL:automatic] [Term] id: UBERON:0005639 name: right lung cranial lobe epithelium xref: EHDAA2:0001751 ! right lung cranial lobe epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002170 ! upper lobe of right lung def: "An epithelium that is part of a upper lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0005640 name: right lung caudal lobe epithelium xref: EHDAA2:0001743 ! right lung caudal lobe epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002171 ! lower lobe of right lung def: "An epithelium that is part of a lower lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0005641 name: otocyst epithelium xref: EHDAA2:0001344 ! otocyst epithelium xref: EMAPA:16671 ! epithelium of otocyst xref: EMAPA:16996 ! epithelium of endolymphatic appendage of otocyst xref: EMAPA:16999 ! epithelium of other part xref: VHOG:0000986 ! otocyst epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003051 ! ear vesicle def: "An epithelium that is part of a ear vesicle." [OBOL:automatic] [Term] id: UBERON:0005642 name: ultimobranchial body epithelium xref: EHDAA2:0002105 ! ultimobranchial body epithelium comment: in EHDAA2, develops_from ventral 4th arch branchial pouch endoderm. Kardong: develops from 5th pouch. PMID:16313389: the most posterior pouch generates the ultimobranchial bodies in most vertebrate classes, mammals do not form this structure. is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003092 ! ultimobranchial body def: "An epithelium that is part of a ultimobranchial body." [OBOL:automatic] [Term] id: UBERON:0005643 name: foregut duodenum epithelium xref: EHDAA2:0000563 ! foregut duodenum epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003286 ! duodenum of foregut def: "An epithelium that is part of a duodenum of foregut." [OBOL:automatic] [Term] id: UBERON:0005644 name: midgut duodenum epithelium xref: EHDAA2:0001192 ! midgut duodenum epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003287 ! duodenum of midgut def: "An epithelium that is part of a duodenum of midgut." [OBOL:automatic] [Term] id: UBERON:0005227 name: manual digit epithelium def: "An epithelium that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "hand digit epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit epithelium" EXACT [OBOL:accepted] synonym: "finger epithelium" EXACT [] xref: VHOG:0001032 xref: EHDAA2:0000406 ! digital region epithelium is_a: UBERON:0000490 ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002389 ! manual digit relationship: develops_from UBERON:0010332 {source="EHDAA2"} ! epithelium of handplate [Term] id: UBERON:0010690 name: manual digit 1 epithelium synonym: "hand digit 1 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1 epithelium" EXACT [OBOL:accepted] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001463 ! manual digit 1 xref: EHDAA2:0000512 ! finger 1 epithelium xref: EMAPA:17430 ! epithelium of digit 1 of fore-paw def: "An epithelium that is part of a manual digit 1." [OBOL:automatic] [Term] id: UBERON:0005645 name: manual digit 2 epithelium synonym: "hand digit 2 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0000518 ! finger 2 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003622 ! manual digit 2 xref: EMAPA:17433 ! epithelium of digit 2 of fore-paw def: "An epithelium that is part of a manual digit 2." [OBOL:automatic] [Term] id: UBERON:0005646 name: manual digit 3 epithelium synonym: "hand digit 3 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0000524 ! finger 3 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003623 ! manual digit 3 xref: EMAPA:17436 ! epithelium of digit 3 of fore-paw def: "An epithelium that is part of a manual digit 3." [OBOL:automatic] [Term] id: UBERON:0005647 name: manual digit 4 epithelium synonym: "hand digit 4 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0000530 ! finger 4 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003624 ! manual digit 4 xref: EMAPA:17439 ! epithelium of digit 4 of fore-paw def: "An epithelium that is part of a manual digit 4." [OBOL:automatic] [Term] id: UBERON:0005648 name: manual digit 5 epithelium synonym: "hand digit 5 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0000536 ! finger 5 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003625 ! manual digit 5 xref: EMAPA:17442 ! epithelium of digit 5 of fore-paw def: "An epithelium that is part of a manual digit 5." [OBOL:automatic] [Term] id: UBERON:0005226 name: pedal digit epithelium def: "An epithelium that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit epithelium" EXACT [OBOL:accepted] synonym: "toe epithelium" EXACT [] xref: VHOG:0001031 intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001466 ! pedal digit is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0003248 {source="EHDAA2"} ! epithelium of footplate [Term] id: UBERON:0010693 name: pedal digit 1 epithelium synonym: "foot digit 1 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 epithelium" EXACT [OBOL:accepted] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003631 ! pedal digit 1 xref: EHDAA2:0002038 ! toe 1 epithelium xref: EMAPA:17461 ! epithelium of digit 1 of hind-paw def: "An epithelium that is part of a pedal digit 1." [OBOL:automatic] [Term] id: UBERON:0005649 name: pedal digit 2 epithelium synonym: "foot digit 2 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0002043 ! toe 2 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003632 ! pedal digit 2 xref: EMAPA:17464 ! epithelium of digit 2 of hind-paw def: "An epithelium that is part of a pedal digit 2." [OBOL:automatic] [Term] id: UBERON:0005650 name: pedal digit 3 epithelium synonym: "foot digit 3 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0002048 ! toe 3 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003633 ! pedal digit 3 xref: EMAPA:17467 ! epithelium of digit 3 of hind-paw def: "An epithelium that is part of a pedal digit 3." [OBOL:automatic] [Term] id: UBERON:0005651 name: pedal digit 4 epithelium synonym: "foot digit 4 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0002053 ! toe 4 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003634 ! pedal digit 4 xref: EMAPA:17470 ! epithelium of digit 4 of hind-paw def: "An epithelium that is part of a pedal digit 4." [OBOL:automatic] [Term] id: UBERON:0005652 name: pedal digit 5 epithelium synonym: "foot digit 5 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 epithelium" EXACT [OBOL:accepted] xref: EHDAA2:0002058 ! toe 5 epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003635 ! pedal digit 5 xref: EMAPA:17473 ! epithelium of digit 5 of hind-paw def: "An epithelium that is part of a pedal digit 5." [OBOL:automatic] [Term] id: UBERON:0005655 name: right lung accessory lobe epithelium xref: EHDAA2:0001735 ! right lung accessory lobe epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004890 ! right lung accessory lobe def: "An epithelium that is part of a right lung accessory lobe." [OBOL:automatic] [Term] id: UBERON:0005657 name: crus commune epithelium xref: RETIRED_EHDAA2:0000332 ! crus commune epithelium xref: EMAPA:17820 ! epithelium of crus commune (also: UBERON:0003241 'epithelium of utricle') xref: VHOG:0000478 ! crus commune epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005600 ! crus commune def: "An epithelium that is part of a crus commune." [OBOL:automatic] [Term] id: UBERON:0005658 name: secondary palatal shelf epithelium xref: EHDAA2:0001365 ! secondary palatal shelf epithelium xref: EMAPA:17363 ! epithelium of palatal shelf of maxillary process xref: EMAPA:17931 ! epithelium of palatal shelf of upper jaw xref: VHOG:0001040 ! palatal shelf epithelium synonym: "palatal shelf epithelium" RELATED [VHOG:0001040] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005619 ! secondary palatal shelf def: "An epithelium that is part of a secondary palatal shelf." [OBOL:automatic] [Term] id: UBERON:0005659 name: primary palate epithelium xref: EHDAA2:0001500 ! primary palate epithelium xref: EMAPA:17643 ! epithelium of primary palate of premaxilla of maxillary process xref: EMAPA:17935 ! epithelium of primary palate of premaxilla of upper jaw xref: VHOG:0001025 ! primary palate epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005620 ! primary palate relationship: develops_from UBERON:0012312 {source="EHDAA2"} ! maxillary process ectoderm def: "An epithelium that is part of a primary palate." [OBOL:automatic] [Term] id: UBERON:0005660 name: 2nd arch ectoderm xref: RETIRED_EHDAA2:0000064 ! 2nd arch ectoderm xref: EMAPA:16398 ! ectoderm of branchial membrane of 2nd arch xref: EMAPA:16277 ! ectoderm of 2nd arch xref: EMAPA:16397 ! ectoderm of branchial groove of 2nd arch xref: VHOG:0001062 ! 2nd arch ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 xref: EHDAA2:0000055 ! 2nd arch ectoderm synonym: "2nd pharyngeal arch ectoderm" EXACT [VHOG:0001062] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001062", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An ectoderm that is part of a pharyngeal arch 2." [OBOL:automatic] [Term] id: UBERON:0005661 name: 3rd arch ectoderm xref: RETIRED_EHDAA2:0000079 ! 3rd arch ectoderm xref: EMAPA:16400 ! ectoderm of 3rd arch xref: EMAPA:16582 ! ectoderm of branchial groove of 3rd arch xref: EMAPA:16584 ! ectoderm of branchial membrane of 3rd arch xref: VHOG:0000946 ! 3rd arch ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 xref: EHDAA2:0000072 ! 3rd arch ectoderm synonym: "3rd pharyngeal arch ectoderm" EXACT [VHOG:0000946] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000946", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An ectoderm that is part of a pharyngeal arch 3." [OBOL:automatic] [Term] id: UBERON:0005662 name: 4th arch ectoderm xref: RETIRED_EHDAA2:0000094 ! 4th arch ectoderm xref: EMAPA:16762 ! ectoderm of branchial groove of 4th arch xref: EMAPA:16764 ! ectoderm of branchial membrane of 4th arch xref: EMAPA:16768 ! ectoderm of 4th arch xref: VHOG:0001095 ! 4th arch ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 xref: EHDAA2:0004032 ! 4th arch ectoderm synonym: "4th pharyngeal arch ectoderm" EXACT [VHOG:0001095] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001095", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An ectoderm that is part of a pharyngeal arch 4." [OBOL:automatic] [Term] id: UBERON:0005664 name: 2nd arch endoderm xref: EHDAA2:0000061 ! 2nd arch endoderm xref: RETIRED_EHDAA2:0000065 ! 2nd arch endoderm xref: EMAPA:16274 ! endoderm of branchial membrane of 2nd arch xref: EMAPA:16276 ! endoderm of branchial pouch of 2nd arch xref: EMAPA:16278 ! endoderm of 2nd arch xref: VHOG:0001108 ! 2nd arch endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 synonym: "2nd pharyngeal arch endoderm" EXACT [VHOG:0001108] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001108", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An endoderm that is part of a pharyngeal arch 2." [OBOL:automatic] [Term] id: UBERON:0005665 name: 3rd arch endoderm xref: RETIRED_EHDAA2:0000080 ! 3rd arch endoderm xref: EMAPA:16401 ! endoderm of 3rd arch xref: EMAPA:16585 ! endoderm of branchial membrane of 3rd arch xref: EMAPA:16587 ! endoderm of branchial pouch of 3rd arch xref: VHOG:0001081 ! 3rd arch endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 xref: EHDAA2:0000075 ! 3rd arch endoderm synonym: "3rd pharyngeal arch endoderm" EXACT [VHOG:0001081] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001081", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An endoderm that is part of a pharyngeal arch 3." [OBOL:automatic] [Term] id: UBERON:0005666 name: 4th arch endoderm xref: RETIRED_EHDAA2:0000095 ! 4th arch endoderm xref: EMAPA:16765 ! endoderm of branchial membrane of 4th arch xref: EMAPA:16767 ! endoderm of branchial pouch of 4th arch xref: EMAPA:16769 ! endoderm of 4th arch xref: VHOG:0001092 ! 4th arch endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 xref: EHDAA2:0004033 ! 4th arch endoderm synonym: "4th pharyngeal arch endoderm" EXACT [VHOG:0001092] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001092", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An endoderm that is part of a pharyngeal arch 4." [OBOL:automatic] [Term] id: UBERON:0005669 name: peritoneal cavity mesothelium xref: EHDAA2:0001447 ! peritoneal cavity mesothelium xref: FMA:18147 ! mesothelium of peritoneum synonym: "mesothelium of peritoneum" EXACT [FMA:18147] xref: EMAPA:16139 ! mesothelium of peritoneal component synonym: "mesothelium of peritoneal component" EXACT [EMAPA:16139] xref: SCTID:34073007 ! Structure of peritoneal mesothelium xref: BTO:0003156 ! peritoneal mesothelium synonym: "peritoneal mesothelium" EXACT [BTO:0003156] intersection_of: UBERON:0001136 ! mesothelium intersection_of: located_in UBERON:0001179 ! peritoneal cavity synonym: "peritoneum mesothelium" EXACT [FMA:18147] def: "A mesothelium that is part of a peritoneal cavity." [OBOL:automatic] [Term] id: UBERON:0005670 name: greater omentum mesothelium xref: RETIRED_EHDAA2:0000721 ! greater omentum mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0005448 ! greater omentum def: "A mesothelium that is part of a greater omentum." [OBOL:automatic] [Term] id: UBERON:0005671 name: greater sac mesothelium xref: RETIRED_EHDAA2:0000725 ! greater sac mesothelium xref: EMAPA:16887 ! mesothelium of greater sac of peritoneal component xref: EMAPA:18455 ! mesothelium of greater sac of peritoneal cavity xref: VHOG:0000440 ! greater sac mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0005449 ! greater sac synonym: "greater sac mehomhelium" RELATED [VHOG:0000440] def: "A mesothelium that is part of a greater sac." [OBOL:automatic] [Term] id: UBERON:0005672 name: right lung endothelium xref: EHDAA2:0001755 ! right lung endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002167 ! right lung def: "An endothelium that is part of a right lung." [OBOL:automatic] [Term] id: UBERON:0005673 name: left lung endothelium xref: EHDAA2:0000961 ! left lung endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002168 ! left lung def: "An endothelium that is part of a left lung." [OBOL:automatic] [Term] id: UBERON:0005674 name: right lung cranial lobe endothelium xref: RETIRED_EHDAA2:0001750 ! right lung cranial lobe endothelium xref: EHDAA:4991 ! endothelium of cranial lobe of right lung intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002170 ! upper lobe of right lung def: "An endothelium that is part of a upper lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0005675 name: right lung caudal lobe endothelium xref: RETIRED_EHDAA2:0001742 ! right lung caudal lobe endothelium xref: EHDAA:4983 ! endothelium of caudal lobe of right lung intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002171 ! lower lobe of right lung def: "An endothelium that is part of a lower lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0005676 name: right lung accessory lobe endothelium xref: RETIRED_EHDAA2:0001734 ! right lung accessory lobe endothelium xref: EHDAA:4975 ! endothelium of accessory lobe of right lung intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004890 ! right lung accessory lobe def: "An endothelium that is part of a right lung accessory lobe." [OBOL:automatic] [Term] id: UBERON:0005677 name: caecum mesentery xref: RETIRED_EHDAA2:0000210 ! caecum mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001153 ! cecum def: "A mesentery that is part of a caecum." [OBOL:automatic] [Term] id: UBERON:0005678 name: right lung cranial lobe segmental bronchus xref: EHDAA2:0001754 ! right lung cranial lobe segmental bronchus intersection_of: UBERON:0002184 ! segmental bronchus intersection_of: part_of UBERON:0002170 ! upper lobe of right lung def: "A segmental bronchus that is part of a upper lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0005679 name: right lung caudal lobe segmental bronchus xref: EHDAA2:0001746 ! right lung caudal lobe segmental bronchus intersection_of: UBERON:0002184 ! segmental bronchus intersection_of: part_of UBERON:0002171 ! lower lobe of right lung def: "A segmental bronchus that is part of a lower lobe of right lung." [OBOL:automatic] [Term] id: UBERON:0005680 name: right lung accessory lobe segmental bronchus xref: EHDAA2:0001738 ! right lung accessory lobe segmental bronchus intersection_of: UBERON:0002184 ! segmental bronchus intersection_of: part_of UBERON:0004890 ! right lung accessory lobe def: "A segmental bronchus that is part of a right lung accessory lobe." [OBOL:automatic] [Term] id: UBERON:0005685 name: midgut dorsal mesentery xref: RETIRED_EHDAA2:0001187 ! midgut dorsal mesentery xref: EMAPA:16722 ! dorsal mesentery of mesentery of midgut xref: EMAPA:17040 ! dorsal mesentery of mesentery of loop xref: EMAPA:17046 ! dorsal mesentery of mesentery of rest of midgut xref: EMAPA:18671 ! dorsal mesentery of mesentery of jejunum of midgut intersection_of: UBERON:0002296 ! dorsal mesentery intersection_of: part_of UBERON:0001045 ! midgut xref: SCTID:361434009 ! Dorsal midgut mesentery def: "A dorsal mesentery that is part of a midgut." [OBOL:automatic] [Term] id: UBERON:0005686 name: caecum dorsal mesentery xref: RETIRED_EHDAA2:0000208 ! caecum dorsal mesentery intersection_of: UBERON:0002296 ! dorsal mesentery intersection_of: part_of UBERON:0001153 ! cecum def: "A dorsal mesentery that is part of a caecum." [OBOL:automatic] [Term] id: UBERON:0005688 name: lens vesicle cavity xref: EHDAA2:0000986 ! lens cavity xref: EMAPA:17164 ! cavity of lens vesicle xref: VHOG:0000531 ! lens vesicle cavity synonym: "lens cavity" BROAD [EHDAA2:0000986] synonym: "cavity of lens vesicle" EXACT [EMAPA:17164] synonym: "cavity of lens" BROAD [] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0005426 ! lens vesicle relationship: part_of UBERON:0005426 ! lens vesicle property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {external_class="VHOG:0000531", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An anatomical cavity that is part of a lens vesicle." [OBOL:automatic] [Term] id: UBERON:0010042 ! 1st arch mesenchyme name: 1st arch mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004362 ! pharyngeal arch 1 xref: EMAPA:16128 ! mesenchyme of 1st arch synonym: "mesenchyme of 1st arch" EXACT [EMAPA:16128] def: "Mesenchyme that is part of a pharyngeal arch 1." [OBOL:automatic] [Term] id: UBERON:0009584 alt_id: UBERON:0010043 name: 1st arch mandibular mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0007237 ! 1st arch mandibular component relationship: part_of UBERON:0007237 {source="EMAPA"} ! 1st arch mandibular component synonym: "mandibular mesenchyme" RELATED [] synonym: "mandibular component mesenchyme" RELATED [] synonym: "mesenchyme of mandibular component" EXACT [EMAPA:16385] synonym: "mesenchymal region of mandibular component of first pharyngeal arch" EXACT [UBERON:cjm] xref: EMAPA:16385 ! mesenchyme of mandibular component xref: EHDAA2:0000034 ! 1st arch mandibular mesenchyme def: "Mesenchyme that is part of a 1st arch mandibular component." [OBOL:automatic] [Term] id: UBERON:0013155 name: 1st arch mandibular ectoderm is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0007237 {source="EHDAA2"} ! 1st arch mandibular component relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm xref: EHDAA2:0000032 ! 1st arch mandibular ectoderm xref: EMAPA:16383 ! ectoderm of mandibular component synonym: "ectoderm of mandibular component" EXACT [EMAPA:16383] [Term] id: UBERON:0013156 name: 1st arch mandibular endoderm is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0007122 {source="EHDAA2"} ! pharyngeal pouch 1 relationship: develops_from UBERON:0007690 {source="EHDAA2"} ! early pharyngeal endoderm relationship: part_of UBERON:0007237 {source="EHDAA2"} ! 1st arch mandibular component relationship: part_of UBERON:0009722 {source="EHDAA2"} ! entire pharyngeal arch endoderm xref: EHDAA2:0000033 ! 1st arch mandibular endoderm xref: EMAPA:16384 ! endoderm of mandibular component synonym: "endoderm of mandibular component" EXACT [EMAPA:16384] [Term] id: UBERON:0006905 name: mandibular process mesenchyme xref: EHDAA2:0001062 ! mandibular process mesenchyme xref: EMAPA:17357 ! mesenchyme of mandibular process xref: EHDAA:5873 ! mesenchyme of mandibular process xref: EHDAA:5861 synonym: "mesenchyme of mandibular process" EXACT [EMAPA:17357] synonym: "mesenchyme of mandibular prominence" EXACT [UBERON:cjm] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005867 ! mandibular prominence def: "Mesenchyme that is part of a mandibular prominence." [OBOL:automatic] [Term] id: UBERON:0010045 name: 1st arch maxillary mesenchyme def: "Mesenchyme that is part of a 1st arch maxillary component." [OBOL:automatic] synonym: "maxillary mesenchyme" RELATED [] synonym: "maxillary component mesenchyme" RELATED [] synonym: "mesenchyme of maxillary component" EXACT [EMAPA:16391] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0007238 ! 1st arch maxillary component xref: EHDAA2:0000041 ! 1st arch maxillary mesenchyme xref: EMAPA:16391 ! mesenchyme of maxillary component [Term] id: UBERON:0012313 name: 1st arch maxillary ectoderm synonym: "ectoderm of maxillary component" EXACT [EMAPA:16389] is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0007238 {source="EHDAA2"} ! 1st arch maxillary component relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm xref: EHDAA2:0000039 ! 1st arch maxillary ectoderm xref: EMAPA:16389 ! ectoderm of maxillary component [Term] id: UBERON:0013154 name: 1st arch maxillary endoderm synonym: "endoderm of maxillary component" EXACT [EMAPA:16390] is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0007122 {source="EHDAA2"} ! pharyngeal pouch 1 relationship: develops_from UBERON:0007690 {source="EHDAA2"} ! early pharyngeal endoderm relationship: part_of UBERON:0007238 {source="EHDAA2"} ! 1st arch maxillary component relationship: part_of UBERON:0009722 {source="EHDAA2"} ! entire pharyngeal arch endoderm xref: EHDAA2:0000040 ! 1st arch maxillary endoderm xref: EMAPA:16390 ! endoderm of maxillary component [Term] id: UBERON:0009526 name: maxillary process mesenchyme subset: emapa_ehdaa2 synonym: "mesenchyme of maxillary process" EXACT [EMAPA:17361] synonym: "mesenchyme of maxillary prominence" EXACT [UBERON:cjm] def: "Mesenchyme that is part of a maxillary prominence." [OBOL:automatic] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005868 ! maxillary prominence xref: EHDAA2:0001071 ! maxillary process mesenchyme xref: EMAPA:17361 ! mesenchyme of maxillary process [Term] id: UBERON:0012312 name: maxillary process ectoderm is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: part_of UBERON:0005868 {source="EHDAA2"} ! maxillary prominence xref: EHDAA2:0004599 ! maxillary process ectoderm xref: EMAPA:17637 ! epithelium of maxillary process [Term] id: UBERON:0005689 name: 2nd arch mesenchyme xref: EHDAA2:0000066 ! 2nd arch mesenchyme xref: EMAPA:16279 ! mesenchyme of 2nd arch xref: EHDAA:625 ! mesenchyme of 2nd arch xref: VHOG:0001102 ! 2nd pharyngeal arch mesenchyme synonym: "2nd pharyngeal arch mesenchyme" EXACT [VHOG:0001102] synonym: "2nd branchial arch mesenchyme" RELATED [] synonym: "pharyngeal arch 2 mesenchyme" RELATED [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001102", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "Mesenchyme that is part of a pharyngeal arch 2." [OBOL:automatic] [Term] id: UBERON:0005690 name: 3rd arch mesenchyme xref: EHDAA2:0000081 ! 3rd arch mesenchyme xref: EMAPA:16402 ! mesenchyme of 3rd arch xref: VHOG:0001083 ! 3rd pharyngeal arch mesenchyme xref: EHDAA:1094 ! mesenchyme of 3rd arch synonym: "3rd pharyngeal arch mesenchyme" EXACT [VHOG:0001083] synonym: "3rd branchial arch mesenchyme" RELATED [] synonym: "pharyngeal arch 3 mesenchyme" RELATED [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001083", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "Mesenchyme that is part of a pharyngeal arch 3." [OBOL:automatic] [Term] id: UBERON:0005691 name: 4th arch mesenchyme xref: EHDAA2:0000096 ! 4th arch mesenchyme xref: EMAPA:16770 ! mesenchyme of 4th arch xref: VHOG:0001052 ! 4th pharyngeal arch mesenchyme xref: EHDAA:1677 ! mesenchyme of 4th arch synonym: "4th pharyngeal arch mesenchyme" EXACT [VHOG:0001052] synonym: "4th branchial arch mesenchyme" RELATED [] synonym: "pharyngeal arch 4 mesenchyme" RELATED [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0001052", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "Mesenchyme that is part of a pharyngeal arch 4." [OBOL:automatic] [Term] id: UBERON:0013502 name: 5th arch mesenchyme synonym: "5th pharyngeal arch mesenchyme" EXACT [VHOG:0001052] synonym: "5th branchial arch mesenchyme" RELATED [] synonym: "pharyngeal arch 5 mesenchyme" RELATED [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003116 ! pharyngeal arch 5 [Term] id: UBERON:0010031 name: 6th arch mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003117 ! pharyngeal arch 6 xref: EHDAA2:0004076 ! 6th arch mesenchyme def: "Mesenchyme that is part of a pharyngeal arch 6." [OBOL:automatic] synonym: "6th pharyngeal arch mesenchyme" EXACT [] synonym: "6th branchial arch mesenchyme" RELATED [] synonym: "pharyngeal arch 6 mesenchyme" RELATED [] [Term] id: UBERON:0010359 name: pharyngeal arch mesenchyme from neural crest comment: Partially implements UBERONREF:0000002 NC meeting scheme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme def: "Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme." [OBOL:automatic] synonym: "branchial arch mesenchyme from neural crest" EXACT [] synonym: "arch mesenchyme from neural crest" EXACT [] synonym: "neural crest derived arch mesenchyme" EXACT [] [Term] id: UBERON:0010360 name: pharyngeal arch mesenchyme from head mesenchyme comment: Partially implements UBERONREF:0000002 NC meeting scheme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme." [OBOL:automatic] synonym: "branchial arch mesenchyme from head mesenchyme" EXACT [] synonym: "arch mesenchyme from head mesenchyme" EXACT [] synonym: "head mesenchyme derived arch mesenchyme" EXACT [] [Term] id: UBERON:0010258 name: mesenchyme from rhombencephalic neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0003852 ! rhombencephalon neural crest relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest xref: EHDAA2:0004423 ! mesenchyme from rhombencephalic neural crest def: "Mesenchyme that develops_from a rhombencephalon neural crest." [OBOL:automatic] [Term] id: UBERON:0010259 ! 1st arch mesenchyme from neural crest name: 1st arch mesenchyme from neural crest xref: EMAPA:16129 ! mesenchyme derived from neural crest of mesenchyme of 1st arch synonym: "mesenchyme derived from neural crest of mesenchyme of 1st arch" EXACT [EMAPA:16129] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010042 ! 1st arch mesenchyme is_a: UBERON:0003104 ! mesenchyme relationship: develops_from UBERON:0003852 {source="EHDAA2-inferred"} ! rhombencephalon neural crest def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 1 mesenchyme from neural crest" RELATED [] synonym: "pharyngeal arch 1 mesenchyme from neural crest" EXACT [] synonym: "neural crest derived arch 1 mesenchyme" EXACT [] [Term] id: UBERON:0010252 name: 1st arch mandibular mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0009584 ! 1st arch mandibular mesenchyme is_a: UBERON:0010259 {source="inferred"} ! 1st arch mesenchyme from neural crest relationship: part_of UBERON:0009584 {source="EHDAA2"} ! 1st arch mandibular mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest relationship: develops_from UBERON:0007098 ! mandibular neural crest xref: EHDAA2:0000037 ! 1st arch mandibular mesenchyme from neural crest def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme." [OBOL:automatic] [Term] id: UBERON:0007098 ! mandibular neural crest name: mandibular neural crest def: "Cranial neural crest that migrates into the mandibular arch." [ZFA:0007064] xref: XAO:0000024 ! mandibular crest xref: ZFA:0007064 ! mandibular neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest relationship: part_of UBERON:0003852 {source="ZFA"} ! rhombencephalon neural crest xref: TAO:0007064 ! mandibular neural crest [Term] id: UBERON:0010253 name: 1st arch maxillary mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010045 ! 1st arch maxillary mesenchyme is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: part_of UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest xref: EHDAA2:0000044 ! 1st arch maxillary mesenchyme from neural crest def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010334 name: maxillary process mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0009526 ! maxillary process mesenchyme is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: develops_from UBERON:0010253 {source="EHDAA2"} ! 1st arch maxillary mesenchyme from neural crest relationship: part_of UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme xref: EHDAA2:0004601 ! maxillary process mesenchyme from neural crest def: "Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010336 name: mandibular process mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0006905 ! mandibular process mesenchyme is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: develops_from UBERON:0010252 {source="EHDAA2"} ! 1st arch mandibular mesenchyme from neural crest relationship: part_of UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme xref: EHDAA2:0004603 ! mandibular process mesenchyme from neural crest def: "Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010341 name: 1st arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010042 ! 1st arch mesenchyme is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: part_of UBERON:0010042 {source="EMAPA"} ! 1st arch mesenchyme xref: EMAPA:16130 ! mesenchyme derived from head mesoderm of mesenchyme of 1st arch synonym: "mesenchyme derived from head mesoderm of mesenchyme of 1st arch" EXACT [EMAPA:16130] def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010338 name: 1st arch maxillary mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010045 ! 1st arch maxillary mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme xref: EHDAA2:0000043 ! 1st arch maxillary mesenchyme from head mesenchyme def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010339 name: 1st arch mandibular mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0009584 ! 1st arch mandibular mesenchyme is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0009584 {source="EHDAA2"} ! 1st arch mandibular mesenchyme xref: EHDAA2:0000036 ! 1st arch mandibular mesenchyme from head mesenchyme def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010335 name: maxillary process mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0009526 ! maxillary process mesenchyme is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: develops_from UBERON:0010338 {source="EHDAA2"} ! 1st arch maxillary mesenchyme from head mesenchyme relationship: part_of UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme xref: EHDAA2:0004602 ! maxillary process mesenchyme from head mesenchyme def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010337 name: mandibular process mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0006905 ! mandibular process mesenchyme is_a: UBERON:0003104 {source="EHDAA2"} ! mesenchyme relationship: develops_from UBERON:0010339 {source="EHDAA2"} ! 1st arch mandibular mesenchyme from head mesenchyme relationship: part_of UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme xref: EHDAA2:0004604 ! mandibular process mesenchyme from head mesenchyme def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme." [OBOL:automatic] [Term] id: UBERON:0010254 name: 2nd arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0005689 ! 2nd arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0007099 ! hyoid neural crest relationship: part_of UBERON:0005689 {source="EHDAA2"} ! 2nd arch mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest xref: EHDAA2:0000068 ! 2nd arch mesenchyme from neural crest xref: EMAPA:16281 ! mesenchyme derived from neural crest of mesenchyme of 2nd arch def: "Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 2 mesenchyme from neural crest" RELATED [] synonym: "pharyngeal arch 2 mesenchyme from neural crest" EXACT [] synonym: "neural crest derived arch 2 mesenchyme" EXACT [] [Term] id: UBERON:0007099 name: hyoid neural crest def: "Cranial neural crest that migrates into the hyoid arch." [ZFA:0007065] synonym: "hyoid crest" EXACT [XAO:0000025] xref: XAO:0000025 ! hyoid crest xref: ZFA:0007065 ! hyoid neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest relationship: part_of UBERON:0003852 {source="ZFA"} ! rhombencephalon neural crest xref: TAO:0007065 ! hyoid neural crest [Term] id: UBERON:0010343 name: 2nd arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0005689 ! 2nd arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0005689 {source="EHDAA2"} ! 2nd arch mesenchyme xref: EHDAA2:0000067 ! 2nd arch mesenchyme from head mesenchyme xref: EMAPA:16280 ! mesenchyme derived from head mesoderm of mesenchyme of 2nd arch synonym: "mesenchyme derived from head mesoderm of mesenchyme of 2nd arch" EXACT [EMAPA:16280] def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 2 mesenchyme from head mesenchyme" RELATED [] synonym: "pharyngeal arch 2 mesenchyme from head mesenchyme" EXACT [] synonym: "head mesenchyme derived arch 2 mesenchyme" EXACT [] [Term] id: UBERON:0010255 name: 3rd arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0005690 ! 3rd arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0003852 {source="EHDAA2-inferred"} ! rhombencephalon neural crest relationship: part_of UBERON:0005690 {source="EHDAA2"} ! 3rd arch mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest xref: EHDAA2:0000083 ! 3rd arch mesenchyme from neural crest xref: EMAPA:16404 ! mesenchyme derived from neural crest of mesenchyme of 3rd arch synonym: "mesenchyme derived from neural crest of mesenchyme of 3rd arch" EXACT [EMAPA:16404] xref: VHOG:0000571 ! 3rd pharyngeal arch mesenchyme derived from neural crest synonym: "3rd pharyngeal arch mesenchyme derived from neural crest" EXACT [VHOG:0000571] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000571", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 3 mesenchyme from neural crest" RELATED [] synonym: "pharyngeal arch 3 mesenchyme from neural crest" EXACT [] synonym: "neural crest derived arch 3 mesenchyme" EXACT [] [Term] id: UBERON:0010344 name: 3rd arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0005690 ! 3rd arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0005690 {source="EHDAA2"} ! 3rd arch mesenchyme xref: EHDAA2:0000082 ! 3rd arch mesenchyme from head mesenchyme xref: EMAPA:16403 ! mesenchyme derived from head mesoderm of mesenchyme of 3rd arch synonym: "mesenchyme derived from head mesoderm of mesenchyme of 3rd arch" EXACT [EMAPA:16403] def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 3 mesenchyme from head mesenchyme" RELATED [] synonym: "pharyngeal arch 3 mesenchyme from head mesenchyme" EXACT [] synonym: "head mesenchyme derived arch 3 mesenchyme" EXACT [] [Term] id: UBERON:0010256 name: 4th arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0005691 ! 4th arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0003852 {source="EHDAA2-inferred"} ! rhombencephalon neural crest relationship: part_of UBERON:0005691 {source="EHDAA2"} ! 4th arch mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest xref: EHDAA2:0000098 ! 4th arch mesenchyme from neural crest xref: EMAPA:16772 ! mesenchyme derived from neural crest of mesenchyme of 4th arch synonym: "mesenchyme derived from neural crest of mesenchyme of 4th arch" EXACT [EMAPA:16772] xref: VHOG:0000580 ! 4th pharyngeal arch mesenchyme derived from neural crest synonym: "4th pharyngeal arch mesenchyme derived from neural crest" EXACT [VHOG:0000580] property_value: homology_notes "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {external_class="VHOG:0000580", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 4 mesenchyme from neural crest" RELATED [] synonym: "pharyngeal arch 4 mesenchyme from neural crest" EXACT [] synonym: "neural crest derived arch 4 mesenchyme" EXACT [] [Term] id: UBERON:0010345 name: 4th arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0005691 ! 4th arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0005691 {source="EHDAA2"} ! 4th arch mesenchyme xref: EHDAA2:0000097 ! 4th arch mesenchyme from head mesenchyme xref: EMAPA:16771 ! mesenchyme derived from head mesoderm of mesenchyme of 4th arch synonym: "mesenchyme derived from head mesoderm of mesenchyme of 4th arch" EXACT [EMAPA:16771] def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 4 mesenchyme from head mesenchyme" RELATED [] synonym: "pharyngeal arch 4 mesenchyme from head mesenchyme" EXACT [] synonym: "head mesenchyme derived arch 4 mesenchyme" EXACT [] [Term] id: UBERON:0010257 name: 6th arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010031 ! 6th arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0003852 {source="EHDAA2-inferred"} ! rhombencephalon neural crest relationship: part_of UBERON:0010031 {source="EHDAA2"} ! 6th arch mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest xref: EHDAA2:0004077 ! 6th arch mesenchyme from neural crest def: "Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 6 mesenchyme from neural crest" RELATED [] synonym: "pharyngeal arch 6 mesenchyme from neural crest" EXACT [] synonym: "neural crest derived arch 6 mesenchyme" EXACT [] [Term] id: UBERON:0010347 name: 6th arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010031 ! 6th arch mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0010031 {source="EHDAA2"} ! 6th arch mesenchyme xref: EHDAA2:0004078 ! 6th arch mesenchyme from head mesenchyme def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 6 mesenchyme from head mesenchyme" RELATED [] synonym: "pharyngeal arch 6 mesenchyme from head mesenchyme" EXACT [] synonym: "head mesenchyme derived arch 6 mesenchyme" EXACT [] [Term] id: UBERON:0010564 name: manual digit 1 mesenchyme synonym: "hand digit 1 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 1 mesenchyme" EXACT [OBOL:accepted] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001463 ! manual digit 1 xref: EHDAA2:0000513 ! finger 1 mesenchyme xref: EMAPA:17431 ! mesenchyme of digit 1 of fore-paw def: "Mesenchyme that is part of a manual digit 1." [OBOL:automatic] [Term] id: UBERON:0005692 name: manual digit 2 mesenchyme synonym: "hand digit 2 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 2 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0000519 ! finger 2 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003622 ! manual digit 2 xref: EMAPA:17434 ! mesenchyme of digit 2 of fore-paw def: "Mesenchyme that is part of a manual digit 2." [OBOL:automatic] [Term] id: UBERON:0005693 name: manual digit 3 mesenchyme synonym: "hand digit 3 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 3 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0000525 ! finger 3 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003623 ! manual digit 3 xref: EMAPA:17437 ! mesenchyme of digit 3 of fore-paw def: "Mesenchyme that is part of a manual digit 3." [OBOL:automatic] [Term] id: UBERON:0005694 name: manual digit 4 mesenchyme synonym: "hand digit 4 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 4 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0000531 ! finger 4 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003624 ! manual digit 4 xref: EMAPA:17440 ! mesenchyme of digit 4 of fore-paw def: "Mesenchyme that is part of a manual digit 4." [OBOL:automatic] [Term] id: UBERON:0005695 name: manual digit 5 mesenchyme synonym: "hand digit 5 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fore limb digit 5 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0000537 ! finger 5 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003625 ! manual digit 5 xref: EMAPA:17443 ! mesenchyme of digit 5 of fore-paw def: "Mesenchyme that is part of a manual digit 5." [OBOL:automatic] [Term] id: UBERON:0005255 name: pedal digit mesenchyme def: "Mesenchyme that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit mesenchyme" EXACT [OBOL:accepted] synonym: "toe mesenchyme" EXACT [] xref: VHOG:0000463 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001466 ! pedal digit relationship: develops_from UBERON:0003328 {source="EHDAA2"} ! mesenchyme of footplate [Term] id: UBERON:0010562 name: pedal digit 1 mesenchyme synonym: "foot digit 1 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 mesenchyme" EXACT [OBOL:accepted] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003631 ! pedal digit 1 xref: EHDAA2:0002039 ! toe 1 mesenchyme xref: EMAPA:17462 ! mesenchyme of digit 1 of hind-paw def: "Mesenchyme that is part of a pedal digit 1." [OBOL:automatic] [Term] id: UBERON:0005696 name: pedal digit 2 mesenchyme synonym: "foot digit 2 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0002044 ! toe 2 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003632 ! pedal digit 2 xref: EMAPA:17465 ! mesenchyme of digit 2 of hind-paw def: "Mesenchyme that is part of a pedal digit 2." [OBOL:automatic] [Term] id: UBERON:0005697 name: pedal digit 3 mesenchyme synonym: "foot digit 3 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0002049 ! toe 3 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003633 ! pedal digit 3 xref: EMAPA:17468 ! mesenchyme of digit 3 of hind-paw def: "Mesenchyme that is part of a pedal digit 3." [OBOL:automatic] [Term] id: UBERON:0005698 name: pedal digit 4 mesenchyme synonym: "foot digit 4 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0002054 ! toe 4 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003634 ! pedal digit 4 xref: EMAPA:17471 ! mesenchyme of digit 4 of hind-paw def: "Mesenchyme that is part of a pedal digit 4." [OBOL:automatic] [Term] id: UBERON:0005699 name: pedal digit 5 mesenchyme synonym: "foot digit 5 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 mesenchyme" EXACT [OBOL:accepted] xref: EHDAA2:0002059 ! toe 5 mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003635 ! pedal digit 5 xref: EMAPA:17474 ! mesenchyme of digit 5 of hind-paw def: "Mesenchyme that is part of a pedal digit 5." [OBOL:automatic] [Term] id: UBERON:0005702 name: optic eminence mesenchyme xref: RETIRED_EHDAA2:0001310 ! optic eminence mesenchyme xref: EMAPA:16324 ! mesenchyme of optic eminence (also: UBERON:0003314 'eye mesenchyme') xref: VHOG:0001073 ! optic eminence mesenchyme xref: EHDAA:942 ! mesenchyme of optic eminence intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004348 ! optic eminence def: "Mesenchyme that is part of a optic eminence." [OBOL:automatic] [Term] id: UBERON:0005704 name: secondary palatal shelf mesenchyme xref: EHDAA2:0001366 ! palatal shelf mesenchyme xref: EMAPA:17364 ! mesenchyme of palatal shelf of maxillary process xref: EMAPA:17932 ! mesenchyme of palatal shelf of upper jaw xref: VHOG:0001063 ! palatal shelf mesenchyme synonym: "palatal shelf mesenchyme" RELATED [VHOG:0001063] xref: EHDAA:9287 ! mesenchyme of palatal shelf intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005619 ! secondary palatal shelf def: "Mesenchyme that is part of a secondary palatal shelf." [OBOL:automatic] [Term] id: UBERON:0005705 name: primary palate mesenchyme xref: EHDAA2:0001501 ! primary palate mesenchyme xref: EMAPA:17644 ! mesenchyme of primary palate of premaxilla of maxillary process xref: EMAPA:17936 ! mesenchyme of primary palate of premaxilla of upper jaw xref: VHOG:0001024 ! primary palate mesenchyme xref: EHDAA:6968 ! mesenchyme of primary palate intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005620 ! primary palate relationship: develops_from UBERON:0010253 {source="EHDAA2"} ! 1st arch maxillary mesenchyme from neural crest relationship: develops_from UBERON:0009204 {source="EHDAA2"} ! medial nasal process mesenchyme def: "Mesenchyme that is part of a primary palate." [OBOL:automatic] [Term] id: UBERON:0005706 name: obsolete central nervous system cranial ganglion consider: EHDAA2:0000226 ! central nervous system cranial ganglion consider: EHDAA:920 ! cranial of ganglion of central nervous system is_obsolete: true replaced_by: UBERON:0001714 ! cranial ganglion [Term] id: UBERON:0003317 name: odontogenic papilla of incisor def: "An odontogenic papilla that is part of a incisor tooth [Automatically generated definition]." [OBOL:automatic] synonym: "incisor odontogenic papilla" EXACT [OBOL:automatic] synonym: "incisor tooth odontogenic papilla" EXACT [OBOL:automatic] synonym: "odontogenic papilla of incisor tooth" EXACT [OBOL:automatic] synonym: "incisor dental papilla" EXACT [UBERON:cjm] synonym: "incisor mesenchyme" EXACT [UBERON:cjm] intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0001098 ! incisor tooth relationship: develops_from UBERON:0010259 {source="EHDAA2-abduced"} ! 1st arch mesenchyme from neural crest [Term] id: UBERON:0011641 name: odontogenic papilla of molar def: "An odontogenic papilla that is part of a molar tooth [Automatically generated definition]." [OBOL:automatic] synonym: "molar odontogenic papilla" EXACT [OBOL:automatic] synonym: "molar tooth odontogenic papilla" EXACT [OBOL:automatic] synonym: "odontogenic papilla of molar tooth" EXACT [OBOL:automatic] synonym: "molar mesenchyme" EXACT [UBERON:cjm] intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003655 ! molar tooth relationship: develops_from UBERON:0010259 {source="EHDAA2-abduced"} ! 1st arch mesenchyme from neural crest [Term] id: UBERON:0005700 name: upper jaw molar odontogenic papilla xref: EHDAA2:0002127 ! upper jaw molar dental papilla xref: EMAPA:17944 ! odontogenic papilla of molar of tooth of upper jaw xref: EHDAA:8051 ! odontogenic papilla synonym: "upper jaw molar dental papilla" EXACT [EHDAA2:0002127] synonym: "upper molar mesenchyme" EXACT [] intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003666 ! upper jaw molar relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest def: "An odontogenic papilla that is part of a upper jaw molar." [OBOL:automatic] [Term] id: UBERON:0005701 name: lower jaw molar odontogenic papilla xref: EHDAA2:0001027 ! lower jaw molar odontogenic papilla xref: EMAPA:17923 ! odontogenic papilla of molar of tooth of lower jaw xref: EHDAA:8015 ! odontogenic papilla synonym: "lower jaw molar dental papilla" EXACT [EHDAA2:0001027] synonym: "lower molar mesenchyme" EXACT [] intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003667 ! lower jaw molar relationship: develops_from UBERON:0010336 {source="EHDAA2"} ! mandibular process mesenchyme from neural crest def: "An odontogenic papilla that is part of a lower jaw molar." [OBOL:automatic] [Term] id: UBERON:0005707 name: upper jaw incisor odontogenic papilla xref: EHDAA2:0002123 ! upper jaw incisor dental papilla xref: EMAPA:17941 ! odontogenic papilla of incisor of tooth of upper jaw synonym: "upper jaw incisor dental papilla" EXACT [EHDAA2:0002123] synonym: "upper incisor mesenchyme" EXACT [] intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003450 ! upper jaw incisor relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest def: "An odontogenic papilla that is part of a upper jaw incisor." [OBOL:automatic] [Term] id: UBERON:0005708 name: lower jaw incisor odontogenic papilla xref: EHDAA2:0001023 ! lower jaw incisor dental papilla xref: EMAPA:17920 ! odontogenic papilla of incisor of tooth of lower jaw synonym: "lower jaw incisor dental papilla" EXACT [EHDAA2:0001023] synonym: "lower incisor mesenchyme" EXACT [] intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003451 ! lower jaw incisor relationship: develops_from UBERON:0010336 {source="EHDAA2"} ! mandibular process mesenchyme from neural crest def: "An odontogenic papilla that is part of a lower jaw incisor." [OBOL:automatic] [Term] id: UBERON:0011642 ! oral epithelium from ectoderm name: oral epithelium from ectoderm is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002424 ! oral epithelium intersection_of: develops_from UBERON:0000924 ! ectoderm relationship: develops_from UBERON:0009479 {source="EHDAA2"} ! ectoderm of buccopharyngeal membrane xref: EHDAA2:0004137 ! oral epithelium from ectoderm def: "An epithelium that develops_from a ectoderm and is part of a oral epithelium." [OBOL:automatic] [Term] id: UBERON:0005709 name: upper jaw incisor epithelium xref: EHDAA2:0002122 ! upper jaw incisor epithelium xref: EMAPA:17940 ! epithelium of incisor of tooth of upper jaw (also: UBERON:0003355 'epithelium of incisor') intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003450 ! upper jaw incisor relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm def: "A dental epithelium that is part of a upper jaw incisor." [OBOL:automatic] [Term] id: UBERON:0005710 name: lower jaw incisor epithelium xref: EHDAA2:0001022 ! lower jaw incisor epithelium xref: EMAPA:17919 ! epithelium of incisor of tooth of lower jaw (also: UBERON:0003355 'epithelium of incisor') intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003451 ! lower jaw incisor relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm def: "A dental epithelium that is part of a lower jaw incisor." [OBOL:automatic] [Term] id: UBERON:0005653 name: upper jaw molar epithelium xref: EMAPA:17943 ! epithelium of molar of tooth of upper jaw (also: UBERON:0003235 'epithelium of upper jaw') xref: EHDAA2:0002126 ! upper jaw molar epithelium intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003666 ! upper jaw molar relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm def: "A dental epithelium that is part of a upper jaw molar." [OBOL:automatic] [Term] id: UBERON:0005654 name: lower jaw molar epithelium xref: EHDAA2:0001026 ! lower jaw molar epithelium xref: EMAPA:17922 ! epithelium of molar of tooth of lower jaw (also: UBERON:0003236 'epithelium of lower jaw') intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003667 ! lower jaw molar relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm def: "A dental epithelium that is part of a lower jaw molar." [OBOL:automatic] [Term] id: UBERON:0005711 name: foregut duodenum mesentery xref: EHDAA2:0000564 ! foregut duodenum mesentery intersection_of: UBERON:0003397 ! mesentery of duodenum intersection_of: part_of UBERON:0001041 ! foregut relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm def: "A mesentery of duodenum that is part of a foregut." [OBOL:automatic] [Term] id: UBERON:0005712 name: midgut duodenum mesentery xref: EHDAA2:0001193 ! midgut duodenum mesentery intersection_of: UBERON:0003397 ! mesentery of duodenum intersection_of: part_of UBERON:0001045 ! midgut relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm def: "A mesentery of duodenum that is part of a midgut." [OBOL:automatic] [Term] id: UBERON:0003842 ! neural tube lumen name: neural tube lumen alt_id: UBERON:0005713 comment: TODO - check synonym: "neural tube neural lumen" EXACT [EHDAA2:0001269] synonym: "neural lumen" RELATED [EHDAA:2889] synonym: "lumen of neural tube" EXACT [UBERON:cjm] synonym: "cavity of neural tube" EXACT [UBERON:cjm] xref: VHOG:0001119 ! neural lumen xref: EHDAA:2889 ! neural lumen xref: EHDAA:914 ! neural lumen xref: EHDAA2:0001269 ! neural tube neural lumen xref: XAO:0000252 ! neurocoel xref: AAO:0011073 ! neurocoel xref: EMAPA:16167 ! neural lumen of neural tube of future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16533 ! neural lumen of neural tube of future spinal cord of central nervous system of nervous system of organ system intersection_of: UBERON:0000464 ! anatomical space intersection_of: surrounded_by UBERON:0001049 ! neural tube synonym: "neurocoel" RELATED [VHOG:0001119] property_value: homology_notes "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {external_class="VHOG:0001119", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An anatomical space that surrounded_by a neural tube." [OBOL:automatic] [Term] id: UBERON:0005719 name: footplate apical ectodermal ridge xref: EHDAA2:0000547 ! footplate apical ectodermal ridge xref: EMAPA:17251 ! apical ectodermal ridge of ectoderm of footplate intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0006871 ! footplate def: "An apical ectodermal ridge that is part of a footplate." [OBOL:automatic] relationship: part_of UBERON:0003373 {is_inferred="true", source="reference_0000032"} ! ectoderm of footplate [Term] id: UBERON:0006872 name: handplate apical ectodermal ridge xref: EMAPA:17247 ! apical ectodermal ridge of ectoderm of handplate xref: EHDAA2:0000729 ! handplate apical ectodermal ridge intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0006875 ! handplate def: "An apical ectodermal ridge that is part of a handplate." [OBOL:automatic] [Term] id: UBERON:0005720 name: hindbrain venous system xref: EHDAA2:0000776 ! hindbrain venous system xref: EMAPA:18632 ! hindbrain of brain of venous system of cardiovascular system of organ system xref: VHOG:0001322 ! hindbrain venous system intersection_of: UBERON:0004582 ! venous system intersection_of: part_of UBERON:0002028 ! hindbrain synonym: "rhombencephalon venous system" RELATED [VHOG:0001322] def: "A venous system that is part of a hindbrain." [OBOL:automatic] [Term] id: UBERON:0004111 ! anatomical conduit name: anatomical conduit def: "any opening in the body." [Wikipedia:Foramen] comment: note that FMA has both conduit and conduit space. In EHDAA2 this is a surface feature synonym: "foramen" NARROW [EHDAA2:0003080] synonym: "foramina" NARROW PLURAL [UBERON:cjm] xref: FMA:242873 ! Anatomical conduit xref: EHDAA2:0003080 ! foramen xref: AEO:0000080 ! foramen is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster [Term] id: UBERON:0005744 name: cranial conduit def: "Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves." [TAO:curator, Wikipedia:Foramina_of_the_skull] comment: AO notes: in FMA and ZFA this is a conduit space, not a conduit. Note there may be some additional disambiguation required: foramen is used loosely in the sense of any opening (e.g. foramen primum). FMA appears to use cranial conduit (undefined) in the sense of any foramen of the skull (includes mental foramen, which is not in the cranium proper). subset: vertebrate_core synonym: "foramen" BROAD [ZFA:0005386] synonym: "foramen of skull" RELATED [Wikipedia:Foramina_of_the_skull] xref: FMA:53165 ! cranial conduit xref: ZFA:0005386 ! foramen xref: TAO:0001736 ! foramen xref: VHOG:0001760 ! foramen intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: part_of UBERON:0003129 ! skull xref: AAO:0010438 ! foramen xref: SCTID:276742007 ! Skull foramen xref: http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png xref: VHOG:0001760 ! foramen synonym: "foramens@fr" RELATED [TAO:0001736] synonym: "foramina@fr" RELATED [TAO:0001736] [Term] id: UBERON:0005745 ! optic canal name: optic canal def: "The short canal through the orbitosphenoid bone at the apex of the orbit that gives passage to the optic nerve and the opthalmic artery[MP]. The optic foramen is the opening to the optic canal. The superior surface of the sphenoid bone is bounded behind by a ridge, which forms the anterior border of a narrow, transverse groove, the chiasmatic groove (optic groove), above and behind which lies the optic chiasma; the groove ends on either side in the optic foramen, which transmits the optic nerve and ophthalmic artery (with accompanying sympathetic nerve fibres) into the orbital cavity. The left and right optic canals are 25mm apart posteriorly and 30mm apart anteriorly. They are funnel-shaped (narrowest anteriorly)." [Wikipedia:Optic_canal, ISBN:0-683-40008-8 "Stedman's Medical Dictionary, 27th edition", MP:0010704] subset: vertebrate_core synonym: "canalis opticus" RELATED [Wikipedia:Optic_canal] synonym: "optic foramen" RELATED [Wikipedia:Optic_canal] xref: FMA:54774 ! optic canal xref: AAO:0000342 ! optic foramen xref: ZFA:0005428 ! optic foramen xref: VHOG:0001408 ! optic foramen (also: UBERON:0006269 'optic foramen') xref: EHDAA:10646 ! optic foramen (also: UBERON:0006269 'optic foramen') is_a: UBERON:0005744 ! cranial conduit xref: SCTID:361732009 ! Entire optic canal xref: TAO:0002025 ! optic foramen synonym: "canalis opticus, foramen opticum ossis sphenoidalis" RELATED LATIN [Wikipedia:Optic_canal] xref: http://upload.wikimedia.org/wikipedia/commons/8/8e/Orbita_mensch.jpg property_value: external_definition "Foramen in the orbital region of the neurocranium for the passage of the optic nerve (cranial nerve II).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002025", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "optic nerve foramen" EXACT [TAO:0002025] property_value: external_definition "An aperture in the root of the lesser wing of the sphenoid bone transmitting the optic nerve. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001408", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/optic+foramen", source="http://bgee.unil.ch/"} relationship: in_lateral_side_of UBERON:0001677 {source="FMA-abduced-lr"} ! sphenoid bone [Term] id: UBERON:0005817 ! neuraxis flexure name: neuraxis flexure def: "An anatomical structure that is regional part of the central nervous system where there is a significant bend of the axis." [ZFIN:Curator] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001017 ! central nervous system xref: ZFA:0005593 ! neuraxis flexure [Term] id: UBERON:0005818 name: cephalic flexure def: "the first flexure, or bend, of the embryonic brain; it appears in the region of the mid-brain. In human embryos it generally occurs at the end of the 3rd week/beginning of 4th. By means of it the fore-brain is bent in a ventral direction around the anterior end of the notochord and fore-gut, with the result that the floor of the fore-brain comes to lie almost parallel with that of the hind-brain. This flexure causes the mid-brain to become, for a time, the most prominent part of the brain, since its dorsal surface corresponds with the convexity of the curve. As a consequence, the cardiac plate, which was previously anterior to the forebrain, approximates its adult location in what will become the thoracic region[WP]. Ventral bend in the brain occurring caudal to the adenohypophyseal placode[ZFA]." [ZFIN:curator, Wikipedia:Cephalic_flexure] comment: TODO - check synonym: "ventral flexure" EXACT [ZFA:0001640] synonym: "midbrain flexure" EXACT [] synonym: "mesencephalic flexure" EXACT [http://www.dartmouth.edu/~rswenson/NeuroSci/chapter_4.html] xref: ZFA:0001640 ! cephalic flexure is_a: UBERON:0005817 ! neuraxis flexure relationship: connects UBERON:0001890 ! forebrain relationship: connects UBERON:0001891 ! midbrain xref: TAO:0002181 ! cephalic flexure synonym: "flexura mesencephalica" RELATED LATIN [Wikipedia:Cephalic_flexure] xref: http://upload.wikimedia.org/wikipedia/commons/c/ce/Gray651.png property_value: external_definition "Ventral bend in the brain occurring caudal to the adenohypophyseal placode.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002181", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0005819 name: cervical flexure def: "ventrally concave flexure of the embryonic brain occurring at the junction of hindbrain and spinal cord[MP]. In humans develops by the 5th week of gestation[WP]." [MP:0000913] is_a: UBERON:0005817 ! neuraxis flexure relationship: connects UBERON:0000955 ! brain relationship: connects UBERON:0002240 ! spinal cord [Term] id: UBERON:0005820 name: pontine flexure def: "a bend in the axis of the embryological central nervous system (the neuraxis). This flexure marks the junction between the metencephalon and the myelencephalon. The division of the rhombencephalon (the early hindbrain) into the metencephalon and the myelencephalon occurs at the 7th week of development. In the mature brain, the metencephalon forms the pons and cerebellum, whilst the myelencephalon forms the medulla oblongata[WP]." [Wikipedia:Pontine_flexure] is_a: UBERON:0005817 ! neuraxis flexure relationship: part_of UBERON:0007277 ! presumptive hindbrain relationship: connects UBERON:0001895 ! metencephalon relationship: connects UBERON:0005290 ! myelencephalon [Term] id: UBERON:0005972 name: tunnel of Corti def: "A triangular, fluid-filled space normally found between the inner and outer rows of supporting pillar cells in the organ of Corti." [MP:0003151] is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0002227 ! spiral organ of cochlea [Term] id: UBERON:0005973 name: blood-inner ear barrier def: "the function of the group of barriers and transport systems which regulate the transport of various substances from blood to inner ear tissue and maintain the microhomeostasis and functional integrity of the inner ear; the endothelial cells of the inner ear blood capillaries, linked to each other by tight junctions, represent the main component of the blood-inner ear barrier" [MP:0004999] is_a: UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001846 ! internal ear [Term] id: UBERON:0005975 name: hair follicle bulge def: "the area located in the bottom of the permanent portion of a resting (telogen) hair follicle where the cells of the external root sheath of the hair follicle are contiguous with the basal layer of the epidermis; this portion of the follicle is involved in the generation of a new hair at the onset of the hair growth cycle (anagen) and contains the hair follicle stem cells" [MP:0009759] synonym: "bulge of hair follicle" EXACT [FMA:70735] xref: FMA:70735 ! bulge of hair follicle xref: BTO:0004904 ! hair follicle bulge is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002073 ! hair follicle [Term] id: UBERON:0005976 name: ansiform lobule crus I def: "." [MP:0010002] comment: TODO - check synonym: "crus II of the ansiform lobule (HVII)" EXACT [NIF_GrossAnatomy:nlx_anat_20081209] synonym: "lobulus ansiform crus II" EXACT [NIF_GrossAnatomy:nlx_anat_20081209] synonym: "lobulus semilunaris inferior" EXACT [NIF_GrossAnatomy:nlx_anat_20081209] synonym: "hemispheric lobule viibi" EXACT [NIF_GrossAnatomy:nlx_anat_20081209] synonym: "superior semilunar lobule " EXACT [FMA:72524] synonym: "superior semilunar lobule" EXACT [FMA:72524] synonym: "first crus of ansiform lobule of cerebellum [h vii a]" EXACT [FMA:72524] synonym: "posterior superior lobule" EXACT [FMA:72524] synonym: "semilunar lobule-2 (superior)" EXACT [FMA:72524] synonym: "superior semilunar lobule of cerebellum" EXACT [FMA:72524] xref: NIF_GrossAnatomy:nlx_anat_20081209 ! Hemispheric Lobule VIIBi xref: FMA:72524 ! superior semilunar lobule xref: ABA:ANcr1 ! Crus 1 is_a: UBERON:0005348 ! ansiform lobule synonym: "lobulus semilunaris superior cerebelli" EXACT LATIN [FMA:TA, FMA:72524] synonym: "crus primum lobuli ansiformis cerebelli [h vii a]" EXACT LATIN [FMA:TA, FMA:72524] [Term] id: UBERON:0005977 name: ansiform lobule crus II def: "." [MP:0010003] comment: TODO - check synonym: "crus I of the ansiform lobule (HVII)" EXACT [NIF_GrossAnatomy:nlx_anat_20081208] synonym: "lobulus ansiform crus I" EXACT [NIF_GrossAnatomy:nlx_anat_20081208] synonym: "lobulus semilunaris superior" EXACT [NIF_GrossAnatomy:nlx_anat_20081208] synonym: "hemispheric lobule viia" EXACT [NIF_GrossAnatomy:nlx_anat_20081208] synonym: "inferior semilunar lobule" EXACT [FMA:72525] synonym: "inferior semilunar lobule of cerebellum" EXACT [FMA:72525] synonym: "posterior inferior lobule" EXACT [FMA:72525] synonym: "second crus of ansiform lobule of cerebellum [h vii a]" EXACT [FMA:72525] synonym: "semilunar lobule-2 (inferior)" EXACT [FMA:72525] xref: NIF_GrossAnatomy:nlx_anat_20081208 ! Hemispheric Lobule VIIA xref: FMA:72525 ! inferior semilunar lobule xref: ABA:ANcr2 ! Crus 2 is_a: UBERON:0005348 ! ansiform lobule synonym: "crus secundum lobuli ansiformis cerebelli [h vii a" EXACT LATIN [FMA:TA, FMA:72525] synonym: "lobulus semilunaris inferior cerebelli" EXACT LATIN [FMA:TA, FMA:72525] [Term] id: UBERON:0005978 name: olfactory bulb outer nerve layer def: "the outermost layer of the olfactory bulb; consists primarily of olfactory afferent axons and ensheathing glia" [MP:0010057] is_a: UBERON:0004001 ! olfactory bulb layer relationship: part_of UBERON:0002264 ! olfactory bulb [Term] id: UBERON:0005979 name: crista terminalis def: "the vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium" [MP:0010495] synonym: "crista terminalis cordis" EXACT [FMA:9236] synonym: "crista terminalis of right atrium" EXACT [FMA:9236] xref: FMA:9236 ! crista terminalis is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002078 ! right atrium synonym: "crista terminalis atrii dextri" EXACT LATIN [FMA:TA, FMA:9236] xref: SCTID:277693004 ! Entire crista terminalis cordis [Term] id: UBERON:0006574 name: pectinate line def: "The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line:" [Wikipedia:Pectinate_line] comment: FMA also has FMA:29321 but it's not clear how this differs synonym: "dentate line" RELATED [Wikipedia:Pectinate_line] synonym: "recto-anal junction" RELATED [Wikipedia:Pectinate_line] synonym: "Hilton's 'white line'" RELATED [EMAPA:19159] synonym: "site of anal membrane" RELATED [EMAPA:19159] synonym: "pectinate line of anal canal" EXACT [FMA:75383] xref: EMAPA:19159 ! pectinate line xref: Wikipedia:Pectinate_line ! pectinate line xref: FMA:75383 ! pectinate line of anal canal intersection_of: UBERON:0000015 ! anatomical boundary intersection_of: adjacent_to UBERON:0000931 ! proctodeum intersection_of: adjacent_to UBERON:0001046 ! hindgut relationship: part_of UBERON:0000159 ! anal canal xref: ncithesaurus:Pectinate_Line ! Pectinate Line xref: SCTID:245445008 ! Pectinate line of anal canal synonym: "linea anocutanea" RELATED LATIN [Wikipedia:Pectinate_line] xref: http://upload.wikimedia.org/wikipedia/commons/7/7b/Hemorrhoid.png xref: UMLS:C0821671 [Term] id: UBERON:0005980 name: pectinate muscle def: "the prominent ridges of atrial myocardium located on the inner surface of most of the right atrium and both the right and left auricular regions[MP]." [MP:0010496, Wikipedia:Musculi_pectinati] synonym: "musculus pectinatus" EXACT [FMA:12226] synonym: "musculi pectinati" EXACT PLURAL [Wikipedia:Musculi_pectinati] xref: FMA:12226 ! pectinate muscle is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002302 ! myocardium of atrium xref: SCTID:277718001 ! Musculi pectinati synonym: "musculi pectinati atrii dextri, musculi pectinati atrii sinistri" RELATED LATIN [Wikipedia:Musculi_pectinati] xref: http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png [Term] id: UBERON:0005981 name: vena cava sinus def: "the portion of the cavity of the right atrium of the heart that receives the blood from the vena cavae and is separated from the rest of the atrium by the crista terminalis" [MP:0010497] synonym: "posterior right atrial cavity" EXACT [FMA:13246] synonym: "sinus venarum cavarum" EXACT [FMA:13246] synonym: "cavity of inflow part of right atrium" EXACT [FMA:13246] xref: FMA:13246 ! cavity of inflow part of right atrium is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002078 ! right atrium [Term] id: UBERON:0005982 name: Bachmann's bundle def: "the impulse conduction tract that originates in the sinoatrial node and transmits signal to the left atrium" [MP:0010517, Wikipedia:Bachmann's_bundle] synonym: "anterior interatrial band" EXACT [UBERON:gg] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002350 {source="MP"} ! conducting system of heart xref: http://upload.wikimedia.org/wikipedia/commons/thumb/0/05/ConductionsystemoftheheartwithouttheHeart.png/350px-ConductionsystemoftheheartwithouttheHeart.png [Term] id: UBERON:0009966 name: internodal tract def: "Subdivision of conducting system of heart which consists of the anterior, middle and posterior internodal tracts beneath the endocardium of interatrial septum and above the attachment of the septal leaflet of tricuspid valve." [FMA:9479] comment: evidence is sparse [http://www.gpnotebook.co.uk/simplepage.cfm?ID=-483065798] There is some functional evidence for the existence of specialized conducting pathways within the atria (termed internodal tracts), although this is controversial[http://www.cvphysiology.com/Arrhythmias/A003.htm]. Editor note: include 3 subtypes? synonym: "internodal fasciculus" EXACT [FMA:9479] synonym: "internodal tract muscle tissue" EXACT [FMA:9479] synonym: "internodal conduction tract" EXACT [] synonym: "interatrial conduction tract" EXACT [] is_a: UBERON:0002385 ! muscle tissue relationship: part_of UBERON:0002350 {source="FMA"} ! conducting system of heart xref: FMA:9479 ! internodal tract [Term] id: UBERON:0005984 name: subendocardium layer def: "the layer of loose fibrous tissue located between the endocardium and myocardium which contains the nerves and the impulse-conducting system (Purkinje fibers) of the heart" [MP:0010546] is_a: UBERON:0005983 ! heart layer [Term] id: UBERON:0005985 name: coronary vessel def: "any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation" [MP:0010551] comment: TODO - change relation from part_of xref: MESH:A07.231.114.269 ! coronary vessel intersection_of: UBERON:0000055 ! vessel intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0005986 name: left branch of atrioventricular bundle def: "Subdivision of conducting system of heart which enters the septal myocardium of left ventricle and is continuous with the anterior, septal and posterior divisions of the left branch of the atrioventricular bundle[FMA]. the left branch of the atrioventricular bundle that separates at the bundle of His, descends the septal wall of the left ventricle and connects to the terminal Purkinje fiber[MP]." [FMA:9487, MP:0010566] synonym: "crus sinistrum (fasciculi atrioventricularis)" EXACT [FMA:9487] synonym: "left bundle branch of bundle of His" EXACT [HP:0005172] synonym: "left posterior bundle" EXACT [MP:0010566] synonym: "left posterior branch" EXACT [MP:0010566] synonym: "left bundle branch" EXACT [MP:0010566] synonym: "left bundle of atrioventricular bundle" EXACT [MP:0010566] synonym: "left crus of atrioventricular bundle" EXACT [MP:0010566] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002350 {source="FMA"} ! conducting system of heart relationship: in_left_side_of UBERON:0002353 ! atrioventricular bundle xref: FMA:9487 ! Left branch of atrioventricular bundle xref: SCTID:277690001 ! Entire left bundle branch xref: galen:LeftBundleBranch ! left bundle branch [Term] id: UBERON:0005987 name: right branch of atrioventricular bundle def: "Subdivision of conducting system of heart which enters the septal myocardium of right ventricle to reach the anterior papillary muscle and then subendocardially to the apex of the heart[FMA]. the right branch of the atrioventricular bundle that separates just below the bundle of His, descends the septal wall of the right ventricle and connects to the terminal Purkinje fibers[MP]." [FMA:9486, MP:0010567] synonym: "right bundle branch of bundle of His" EXACT [] synonym: "crus dextrum (fasciculi atrioventricularis)" EXACT [FMA:9486] synonym: "right bundle branch" EXACT [FMA:9486] synonym: "right bundle" EXACT [FMA:9486, MP:0010567] synonym: "right right crus of atrioventricular bundle" EXACT [MP:0010567] synonym: "right ventricular bundle" EXACT [MP:0010567] is_a: UBERON:0000061 ! anatomical structure relationship: in_right_side_of UBERON:0002353 ! atrioventricular bundle relationship: part_of UBERON:0002350 {source="FMA"} ! conducting system of heart xref: FMA:9486 ! right branch of atrioventricular bundle xref: SCTID:277689005 ! Entire right branch of atrioventricular bundle xref: galen:RightBundleBranch ! right bundle branch [Term] id: UBERON:0005988 name: atrium myocardial trabecula def: "the supporting bundles of muscular fibers lining the walls of the atria" [MP:0010581] synonym: "atrium myocardial trabeculae" EXACT PLURAL [MP:0010581] synonym: "trabecula of atrium" EXACT [] synonym: "atrial trabecula" EXACT [] is_a: UBERON:0000440 ! trabecula relationship: part_of UBERON:0002302 ! myocardium of atrium [Term] id: UBERON:0005989 name: atrioventricular septum def: "the wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve" [MP:0010592] synonym: "membranous atrioventricular septum" EXACT [FMA:7136] xref: FMA:7136 ! atrioventricular septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: adjacent_to UBERON:0002084 ! left ventricle intersection_of: adjacent_to UBERON:0002078 ! right atrium relationship: develops_from UBERON:0002062 {source="Wikipedia", source="PMID:15797462"} ! endocardial cushion xref: SCTID:280151006 ! Entire atrioventricular septum [Term] id: UBERON:0006009 ! cusp of cardiac valve name: cusp of cardiac valve def: "Organ component which has as its parts the cusp proper, lunule and nodule of semilunar valvule[FMA]. The cusps of the heart valves serve to seal the heart valves when closed. There are three cusps for each valve except for the mitral valve, which has only two (hence its alternate name, \"bicuspid valve\"). \"Nodules\" are located at the tip of the valve, to form a tighter seal[WP]." [Wikipedia:Cusps_of_heart_valves, FMA:7232] synonym: "cardial valve cusp" EXACT [] synonym: "cardiac valve cusp" EXACT [FMA:7232] synonym: "cardiac valvular cusp" EXACT [FMA:7232] synonym: "cardiac valvule" EXACT [FMA:7232] synonym: "semilunar valvule" EXACT [FMA:7232] xref: FMA:7232 ! cusp of cardiac valve is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000946 ! cardial valve xref: ncithesaurus:Cardiac_Valve_Cusp ! Cardiac Valve Cusp xref: SCTID:30822008 ! Entire cardiac valve cusp xref: http://upload.wikimedia.org/wikipedia/commons/5/50/Gray495.png xref: UMLS:C0225923 [Term] id: UBERON:0005990 name: aortic valve cusp def: "the three fibrous triangular components and associated flap of the aortic valve" [MP:0010595] synonym: "cusp of aortic valve" EXACT [FMA:7251] synonym: "aortic semilunar valvule" EXACT [FMA:7251] synonym: "aortic valvular cusp" EXACT [FMA:7251] synonym: "semilunar valvule of aortic valve" EXACT [FMA:7251] xref: FMA:7251 ! cusp of aortic valve is_a: UBERON:0006009 ! cusp of cardiac valve relationship: part_of UBERON:0002137 ! aortic valve xref: SCTID:362026005 ! Entire cusp of aortic valve [Term] id: UBERON:0005991 name: aortic valve anulus def: "the fibrous ring of the aortic valve that attaches the cusps of aortic valve to the wall of left ventricle, and which consists of portions of the fibrous scallops of the posterior, right anterior and left anterior cusps" [MP:0010598] synonym: "fibrous ring of aortic valve" EXACT [FMA:9502] synonym: "anulus of aortic valve" EXACT [FMA:9502] synonym: "aortic anulus" EXACT [FMA:9502] synonym: "aortic valvar anulus" EXACT [FMA:9502] xref: FMA:9502 ! fibrous ring of aortic valve is_a: UBERON:0006008 ! fibrous ring of heart relationship: part_of UBERON:0002137 ! aortic valve [Term] id: UBERON:0005992 name: pulmonary valve cusp def: "the three fibrous triangular components and associated flap of the pulmonary valve" [MP:0010602] synonym: "cusp of pulmonary valve" EXACT [FMA:7248] synonym: "pulmonary semilunar valvule" EXACT [FMA:7248] synonym: "pulmonary valvular cusp" EXACT [FMA:7248] synonym: "semilunar cusp of pulmonary valve" EXACT [FMA:7248] synonym: "semilunar valvule of pulmonary valve" EXACT [FMA:7248] xref: FMA:7248 ! cusp of pulmonary valve is_a: UBERON:0006009 ! cusp of cardiac valve relationship: part_of UBERON:0002146 ! pulmonary valve [Term] id: UBERON:0005993 name: pulmonary valve anulus def: "the fibrous ring of the pulmonary valve that attaches the cusps of pulmonary valve to the wall of right ventricle, and which consists of portions of the fibrous scallops of the anterior, right posterior and left posterior cusps" [MP:0010606] synonym: "fibrous ring of pulmonary valve" EXACT [FMA:9503] synonym: "anulus of pulmonary valve" EXACT [FMA:9503] synonym: "pulmonary anulus" EXACT [FMA:9503] synonym: "pulmonary valvar anulus" EXACT [FMA:9503] xref: FMA:9503 ! fibrous ring of pulmonary valve is_a: UBERON:0006008 ! fibrous ring of heart relationship: part_of UBERON:0002146 ! pulmonary valve [Term] id: UBERON:0005994 name: chordae tendineae def: "the tendinous strands that connect the papillary muscles on the wall of the ventricles to the leaflets of the atrioventricular valves; the chordae tendineae serve to prevent the AV valves from prolapsing back into the atria" [MP:0010608, Wikipedia:Chordae_tendineae] synonym: "chorda tendinea" EXACT [FMA:12225] xref: GAID:564 ! chordae tendineae xref: FMA:12225 ! Chorda tendinea xref: MESH:A07.541.510.240 ! chordae tendineae is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002133 ! atrioventricular valve xref: ncithesaurus:Chordae_Tendineae ! Chordae Tendineae synonym: "chordae tendineae cordis" RELATED LATIN [Wikipedia:Chordae_tendineae] xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png xref: SCTID:279330004 ! Entire chordae tendineae cordis xref: UMLS:C0008484 [Term] id: UBERON:0005995 name: mitral valve anulus def: "the fibrous ring of the mitral valve that attaches the cusps of mitral valve to the heart, and which consists of portions of the fibrous scallops of the anterior and posterior cusps" [MP:0010613] synonym: "fibrous ring of mitral valve" EXACT [FMA:9498] synonym: "anulus of mitral valve" EXACT [FMA:9498] synonym: "mitral anulus" EXACT [FMA:9498] synonym: "mitral valvar anulus" EXACT [FMA:9498] xref: FMA:9498 ! fibrous ring of mitral valve is_a: UBERON:0006008 ! fibrous ring of heart relationship: part_of UBERON:0002135 ! mitral valve [Term] id: UBERON:0005996 name: mitral valve cusp def: "the two fibrous components and associated flaps of the mitral valve" [MP:0010614] comment: TODO - add generic parent is_a: UBERON:0006009 ! cusp of cardiac valve relationship: part_of UBERON:0002135 ! mitral valve [Term] id: UBERON:0005997 name: tricuspid valve anulus def: "the fibrous ring of the tricuspid valve that attaches the cusps of tricuspid valve to the heart, and which consists of portions of the fibrous scallops of the anterior cusp (infundibular cusp), the posterior cusp (marginal cusp), and the septal cusp (medial cusp)" [MP:0010621] synonym: "fibrous ring of tricuspid valve" EXACT [FMA:9500] synonym: "anulus of tricuspid valve" EXACT [FMA:9500] synonym: "tricuspid anulus" EXACT [FMA:9500] synonym: "tricuspid valvar anulus" EXACT [FMA:9500] xref: FMA:9500 ! fibrous ring of tricuspid valve is_a: UBERON:0006008 ! fibrous ring of heart relationship: part_of UBERON:0002134 ! tricuspid valve [Term] id: UBERON:0005998 name: tricuspid valve cusp def: "the three fibrous triangular components and associated flaps of the tricuspid valve" [MP:0010622] comment: TODO - check synonym: "septal leaflet of tricuspid valve" EXACT [FMA:7240] synonym: "septal cusp of right atrioventricular valve" EXACT [FMA:7240] synonym: "septal cusp of tricuspid valve" EXACT [FMA:7240] synonym: "septal tricuspid leaflet" EXACT [FMA:7240] xref: FMA:7240 ! septal leaflet of tricuspid valve is_a: UBERON:0006009 ! cusp of cardiac valve is_a: UBERON:0005484 ! tricuspid valve leaflet relationship: part_of UBERON:0002134 ! tricuspid valve synonym: "cuspis septalis valvae atrioventricularis dextrae" EXACT LATIN [FMA:TA, FMA:7240] xref: SCTID:261417002 ! Entire septal leaflet of tricuspid valve [Term] id: UBERON:0006001 name: intersomitic artery def: "the small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries" [MP:0010662] is_a: UBERON:0001637 ! artery relationship: part_of UBERON:0005805 ! dorsal aorta xref: XAO:0004165 ! intersomitic artery [Term] id: UBERON:0006002 name: vitelline artery def: "the paired arteries that carry blood to the yolk sac / gut tube from the dorsal aorta; the vitelline arteries give rise to the celiac artery, superior mesenteric artery, and inferior mesenteric artery in the adult" [MP:0010664, Wikipedia:Vitelline_arteries] xref: EMAPA:16207 ! vitelline artery xref: EHDAA2:0002208 ! vitelline artery intersection_of: UBERON:0001637 ! artery intersection_of: continuous_with UBERON:0005805 {notes="ventral branch"} ! dorsal aorta intersection_of: continuous_with UBERON:0001040 ! yolk sac xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Gray31.png [Term] id: UBERON:0006003 name: skin adnexa def: "the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails" [MP:0010678, Wikipedia:Skin_appendage, http://code.google.com/p/caro2/issues/detail?id=5] comment: editor note - add subclasses based on resolution of CARO tracker item. Also check: adnexal gland is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002416 ! integumental system synonym: "adnexae cutis" RELATED LATIN [Wikipedia:Skin_appendage] [Term] id: UBERON:0011901 name: hair matrix comment: The hair matrix surrounds the top and sides of the dermal papilla. The hair matrix cells give rise to 6 different types of cells that make up the different layers of the hair shaft and the inner root sheath. is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001037 {source="FMA"} ! strand of hair xref: FMA:70945 ! hair matrix [Term] id: UBERON:0006004 name: hair follicle matrix region def: "the bulb region adjacent to the dermal papilla that contains rapidly proliferating matrix cells that give rise to the various cell lineages of the hair shaft and inner root sheath" [MP:0010686] synonym: "germinal matrix of hair bulb" EXACT [FMA:70772] synonym: "lower part of bulb of hair follicle" EXACT [FMA:70772] synonym: "lower zone of bulb of hair follicle" EXACT [FMA:70772] synonym: "lower part of bulb of hair follicle" EXACT [FMA:70772] xref: FMA:70772 ! lower zone of bulb of hair follicle is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0005932 ! bulb of hair follicle relationship: has_part CL:0000148 {source="FMA"} ! melanocyte relationship: has_part CL:0000453 {source="FMA"} ! Langerhans cell [Term] id: UBERON:0006005 name: hair follicle isthmus def: "the middle part of the hair follicle that extends from the sebaceous duct to the bulge" [MP:0010694] synonym: "isthmus of hair follicle" EXACT [FMA:70723] xref: FMA:70723 ! isthmus of hair follicle is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002073 ! hair follicle xref: ncithesaurus:Hair_Follicle_Isthmus ! Hair Follicle Isthmus xref: UMLS:C1182701 [Term] id: UBERON:0006006 name: metoptic pilar def: "posterior border of the optic nerve foramen." [MP:0010705] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0005745 ! optic canal [Term] id: UBERON:0006007 name: pre-Botzinger complex def: "the group of interneurons within the medulla oblongata's ventral respiratory group that are important for the generation of ventilatory (inspiratory) rhythmogenesis[MP]. The Pre-Bötzinger Complex (preBötC) is a cluster of interneurons in the ventrolateral medulla of the brainstem, which is essential to the generation of respiratory rhythm in mammals[WP]." [MP:0010745, Wikipedia:Pre-botzinger_complex] comment: the MP class implies this is part of both the medulla oblongata and the PSNS, which violates the spatial disjointness constraint. We weaken this to continuous_with here. synonym: "preBötC" EXACT [Wikipedia:Pre-botzinger_complex] synonym: "Pre-Bötzinger Complex" EXACT [Wikipedia:Pre-botzinger_complex] xref: MA:0002577 ! pre-botzinger complex is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001896 ! medulla oblongata relationship: continuous_with UBERON:0000011 ! parasympathetic nervous system relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia synonym: "pre-botzinger respiratory control center" RELATED [MA:0002577] [Term] id: UBERON:0010858 ! inter limb-segment region name: inter limb-segment region synonym: "interlimb" RELATED [] comment: Examples - region between digits in a human embryo; segments of a bat's patagium is_a: UBERON:0000475 ! organism subdivision relationship: connected_to UBERON:0002529 {cardinality="2"} ! limb segment [Term] id: UBERON:0006012 ! interdigital region name: interdigital region comment: AO notes: MA and EMAPA mapping from TH synonym: "interdigit region" EXACT [] synonym: "interdigit" RELATED [BTO:0004670] xref: MA:0003012 ! interdigital region xref: BTO:0004670 ! interdigit xref: EMAPA:32618 ! interdigital region is_a: UBERON:0010858 ! inter limb-segment region relationship: connected_to UBERON:0002544 {cardinality="2"} ! digit relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0009585 ! interdigital region mesenchyme name: interdigital region mesenchyme comment: influences identity of anterior digit[Dahn and Fallon 2000], likely via BMP4 synonym: "interdigit mesenchyme" RELATED [] synonym: "interdigital mesenchyme" EXACT [] synonym: "mesenchyme of interdigital region" EXACT [] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006012 ! interdigital region def: "Mesenchyme that is part of a interdigital region." [OBOL:automatic] [Term] id: UBERON:0006013 name: interdigital region between manual digits synonym: "hand interdigit region" EXACT [MA:0000627] synonym: "interdigital region of manus" EXACT [] synonym: "manual interdigital region" EXACT [] xref: MA:0000627 ! hand interdigit region xref: VHOG:0000991 ! hand interdigital region intersection_of: UBERON:0006012 ! interdigital region intersection_of: part_of UBERON:0002398 ! manus relationship: adjacent_to UBERON:0002389 {cardinality="2"} ! finger synonym: "hand interdigital region" EXACT [VHOG:0000991] def: "An interdigital region that is part of a manus." [OBOL:automatic] [Term] id: UBERON:0006014 name: interdigital region between pedal digits synonym: "foot interdigit region" EXACT [MA:0000651] synonym: "interdigit region of pes" EXACT [] synonym: "pedal interdigit region" EXACT [] xref: MA:0000651 ! foot interdigit region xref: VHOG:0000992 ! foot interdigital region intersection_of: UBERON:0006012 ! interdigital region intersection_of: part_of UBERON:0002387 ! pes relationship: adjacent_to UBERON:0001466 {cardinality="2"} ! toe synonym: "foot interdigital region" EXACT [VHOG:0000992] def: "An interdigital region that is part of a pes." [OBOL:automatic] [Term] id: UBERON:0006015 ! webbed interdigital region name: webbed interdigital region def: "Interdigital webbing is the presence of membranes of skin between the digits. Normally in mammals, webbing is present in the embryo but resorbed later in development, but in various mammal species it occasionally persists in adulthood.[1] In humans, it can be found in those suffering from LEOPARD syndrome and from Aarskog-Scott syndrome. Webbing between the digits of the hindfoot is also present in several mammals that spend part of their time in the water.[3] Webbing accommodates movement in the water[WP]." [Wikipedia:Interdigital_webbing] synonym: "web" BROAD [] synonym: "interdigital webbing" EXACT [] synonym: "syndactylous interdigital region" EXACT [] is_a: UBERON:0006012 ! interdigital region relationship: part_of UBERON:0008440 ! webbed autopod [Term] id: UBERON:0008438 name: webbed interdigital region between manual digits intersection_of: UBERON:0006015 ! webbed interdigital region intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0008441 ! webbed manus def: "A webbed interdigital region that is part of a manus." [OBOL:automatic] [Term] id: UBERON:0008439 name: webbed interdigital region between pedal digits synonym: "toe web" EXACT [OBOL:automatic] intersection_of: UBERON:0006015 ! webbed interdigital region intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0008442 ! webbed pes def: "A webbed interdigital region that is part of a pes." [OBOL:automatic] [Term] id: UBERON:0008440 ! webbed autopod name: webbed autopod intersection_of: UBERON:0002470 ! autopod region intersection_of: has_part UBERON:0006015 ! webbed interdigital region def: "An autopod region that has_part a webbed interdigital region." [OBOL:automatic] [Term] id: UBERON:0008441 ! webbed manus name: webbed manus synonym: "hand webbing" RELATED [AAO:0010120] synonym: "webbed hand" RELATED [] intersection_of: UBERON:0002398 ! manus intersection_of: has_part UBERON:0006015 ! webbed interdigital region xref: AAO:0010120 ! hand webbing def: "A manus that has_part a webbed interdigital region." [OBOL:automatic] [Term] id: UBERON:0008442 ! webbed pes name: webbed pes synonym: "foot webbing" RELATED [AAO:0010121] synonym: "webbed foot" EXACT [] intersection_of: UBERON:0002387 ! pes intersection_of: has_part UBERON:0006015 ! webbed interdigital region xref: AAO:0010121 ! foot webbing def: "A pes that has_part a webbed interdigital region." [OBOL:automatic] [Term] id: UBERON:0008443 name: webbed digit intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:0008440 ! webbed autopod def: "A digit that is part of a webbed autopod." [OBOL:automatic] [Term] id: UBERON:0008444 name: webbed manual digit synonym: "webbed finger" EXACT [OBOL:automatic] synonym: "digit of webbed manus" EXACT [OBOL:automatic] synonym: "digit of webbed hand" EXACT [OBOL:automatic] intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:0008441 ! webbed manus def: "A digit that is part of a webbed manus." [OBOL:automatic] [Term] id: UBERON:0008445 name: webbed pedal digit synonym: "webbed toe" EXACT [OBOL:automatic] synonym: "digit of webbed pes" EXACT [OBOL:automatic] synonym: "digit of webbed foot" EXACT [OBOL:automatic] intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:0008442 ! webbed pes def: "A digit that is part of a webbed pes." [OBOL:automatic] [Term] id: UBERON:0006016 name: interdigital region between digits 1 and 2 is_a: UBERON:0006012 ! interdigital region intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0006048 ! digit 1 intersection_of: adjacent_to UBERON:0006049 ! digit 2 relationship: part_of UBERON:0002470 ! autopod region def: "An interdigital region that adjacent_to a digit 1 and adjacent_to a digit 2." [OBOL:automatic] [Term] id: UBERON:0006019 name: interdigital region between digits 2 and 3 is_a: UBERON:0006012 ! interdigital region intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0006049 ! digit 2 intersection_of: adjacent_to UBERON:0006050 ! digit 3 relationship: part_of UBERON:0002470 ! autopod region def: "An interdigital region that adjacent_to a digit 2 and adjacent_to a digit 3." [OBOL:automatic] [Term] id: UBERON:0006022 name: interdigital region between digits 3 and 4 is_a: UBERON:0006012 ! interdigital region intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0006050 ! digit 3 intersection_of: adjacent_to UBERON:0006051 ! digit 4 relationship: part_of UBERON:0002470 ! autopod region def: "An interdigital region that adjacent_to a digit 3 and adjacent_to a digit 4." [OBOL:automatic] [Term] id: UBERON:0006025 name: interdigital region between digits 4 and 5 is_a: UBERON:0006012 ! interdigital region intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0006051 ! digit 4 intersection_of: adjacent_to UBERON:0006052 ! digit 5 relationship: part_of UBERON:0002470 ! autopod region def: "An interdigital region that adjacent_to a digit 4 and adjacent_to a digit 5." [OBOL:automatic] [Term] id: UBERON:0006026 name: interdigital region between manual digits 1 and 2 xref: EHDAA2:0000844 ! interdigital region between fingers 1 and 2 xref: EHDAA:6298 ! interdigital region between digits 1 and 2 xref: EMAPA:17445 ! interdigital region between digits 1 and 2 of fore-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0001463 ! manual digit 1 intersection_of: adjacent_to UBERON:0003622 ! manual digit 2 relationship: part_of UBERON:0002398 ! manus def: "An interdigital region that adjacent_to a manual digit 1 and adjacent_to a manual digit 2." [OBOL:automatic] [Term] id: UBERON:0006029 name: interdigital region between manual digits 2 and 3 xref: EHDAA2:0000847 ! interdigital region between fingers 2 and 3 xref: EHDAA:6304 ! interdigital region between digits 2 and 3 xref: EMAPA:17448 ! interdigital region between digits 2 and 3 of fore-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0003622 ! manual digit 2 intersection_of: adjacent_to UBERON:0003623 ! manual digit 3 relationship: part_of UBERON:0002398 ! manus def: "An interdigital region that adjacent_to a manual digit 2 and adjacent_to a manual digit 3." [OBOL:automatic] [Term] id: UBERON:0006032 name: interdigital region between manual digits 3 and 4 xref: EHDAA2:0000850 ! interdigital region between fingers 3 and 4 xref: EHDAA:6310 ! interdigital region between digits 3 and 4 xref: EMAPA:17451 ! interdigital region between digits 3 and 4 of fore-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0003623 ! manual digit 3 intersection_of: adjacent_to UBERON:0003624 ! manual digit 4 relationship: part_of UBERON:0002398 ! manus def: "An interdigital region that adjacent_to a manual digit 3 and adjacent_to a manual digit 4." [OBOL:automatic] [Term] id: UBERON:0006035 name: interdigital region between manual digits 4 and 5 xref: EHDAA2:0000853 ! interdigital region between fingers 4 and 5 xref: EHDAA:6316 ! interdigital region between digits 4 and 5 xref: EMAPA:17454 ! interdigital region between digits 4 and 5 of fore-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0003624 ! manual digit 4 intersection_of: adjacent_to UBERON:0003625 ! manual digit 5 relationship: part_of UBERON:0002398 ! manus def: "An interdigital region that adjacent_to a manual digit 4 and adjacent_to a manual digit 5." [OBOL:automatic] [Term] id: UBERON:0006038 name: interdigital region between pedal digits 1 and 2 xref: EHDAA2:0000856 ! interdigital region between toes 1 and 2 xref: EHDAA:6148 ! interdigital region between digits 1 and 2 xref: EMAPA:17476 ! interdigital region between digits 1 and 2 of hind-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0003631 ! pedal digit 1 intersection_of: adjacent_to UBERON:0003632 ! pedal digit 2 relationship: part_of UBERON:0002387 ! pes def: "An interdigital region that adjacent_to a pedal digit 1 and adjacent_to a pedal digit 2." [OBOL:automatic] [Term] id: UBERON:0006041 name: interdigital region between pedal digits 2 and 3 xref: EHDAA2:0000859 ! interdigital region between toes 2 and 3 xref: EHDAA:6154 ! interdigital region between digits 2 and 3 xref: EMAPA:17479 ! interdigital region between digits 2 and 3 of hind-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0003632 ! pedal digit 2 intersection_of: adjacent_to UBERON:0003633 ! pedal digit 3 relationship: part_of UBERON:0002387 ! pes def: "An interdigital region that adjacent_to a pedal digit 2 and adjacent_to a pedal digit 3." [OBOL:automatic] [Term] id: UBERON:0006044 name: interdigital region between pedal digits 3 and 4 xref: EHDAA2:0000862 ! interdigital region between toes 3 and 4 xref: EHDAA:6160 ! interdigital region between digits 3 and 4 xref: EMAPA:17482 ! interdigital region between digits 3 and 4 of hind-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0003633 ! pedal digit 3 intersection_of: adjacent_to UBERON:0003634 ! pedal digit 4 relationship: part_of UBERON:0002387 ! pes def: "An interdigital region that adjacent_to a pedal digit 3 and adjacent_to a pedal digit 4." [OBOL:automatic] [Term] id: UBERON:0006047 name: interdigital region between pedal digits 4 and 5 xref: EHDAA2:0000865 ! interdigital region between toes 4 and 5 xref: EHDAA:6166 ! interdigital region between digits 4 and 5 xref: EMAPA:17485 ! interdigital region between digits 4 and 5 of hind-paw intersection_of: UBERON:0006012 ! interdigital region intersection_of: adjacent_to UBERON:0003634 ! pedal digit 4 intersection_of: adjacent_to UBERON:0003635 ! pedal digit 5 relationship: part_of UBERON:0002387 ! pes def: "An interdigital region that adjacent_to a pedal digit 4 and adjacent_to a pedal digit 5." [OBOL:automatic] [Term] id: UBERON:0009586 name: mesenchyme of interdigital region between manual digits 1 and 2 relationship: part_of UBERON:0006026 {source="EMAPA"} ! interdigital region between fingers 1 and 2 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006026 ! interdigital region between fingers 1 and 2 xref: EMAPA:17447 ! mesenchyme of interdigital region between digits 1 and 2 of forelimb xref: EHDAA2:0000846 ! interdigital region between fingers 1 and 2 mesenchyme synonym: "interdigital region between fingers 1 and 2 mesenchyme" EXACT [EHDAA2:0000846] def: "An interdigital region mesenchyme that is part of a interdigital region between manual digits 1 and 2." [OBOL:automatic] [Term] id: UBERON:0009587 name: mesenchyme of interdigital region between manual digits 2 and 3 relationship: part_of UBERON:0006029 {source="EMAPA"} ! interdigital region between fingers 2 and 3 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006029 ! interdigital region between fingers 2 and 3 xref: EMAPA:17450 ! mesenchyme of interdigital region between digits 2 and 3 of forelimb xref: EHDAA2:0000849 ! interdigital region between fingers 2 and 3 mesenchyme synonym: "interdigital region between fingers 2 and 3 mesenchyme" EXACT [EHDAA2:0000849] def: "An interdigital region mesenchyme that is part of a interdigital region between manual digits 2 and 3." [OBOL:automatic] [Term] id: UBERON:0009588 name: mesenchyme of interdigital region between manual digits 3 and 4 relationship: part_of UBERON:0006032 {source="EMAPA"} ! interdigital region between fingers 3 and 4 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006032 ! interdigital region between fingers 3 and 4 xref: EMAPA:17453 ! mesenchyme of interdigital region between digits 3 and 4 of forelimb xref: EHDAA2:0000852 ! interdigital region between fingers 3 and 4 mesenchyme synonym: "interdigital region between fingers 3 and 4 mesenchyme" EXACT [EHDAA2:0000852] def: "An interdigital region mesenchyme that is part of a interdigital region between manual digits 3 and 4." [OBOL:automatic] [Term] id: UBERON:0009589 name: mesenchyme of interdigital region between manual digits 4 and 5 relationship: part_of UBERON:0006035 {source="EMAPA"} ! interdigital region between fingers 4 and 5 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006035 ! interdigital region between fingers 4 and 5 xref: EMAPA:17456 ! mesenchyme of interdigital region between digits 4 and 5 of forelimb xref: EHDAA2:0000855 ! interdigital region between fingers 4 and 5 mesenchyme synonym: "interdigital region between fingers 4 and 5 mesenchyme" EXACT [EHDAA2:0000855] def: "An interdigital region mesenchyme that is part of a interdigital region between manual digits 4 and 5." [OBOL:automatic] [Term] id: UBERON:0009590 name: mesenchyme of interdigital region between pedal digits 1 and 2 relationship: part_of UBERON:0006038 {source="EMAPA"} ! interdigital region between toes 1 and 2 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006038 ! interdigital region between toes 1 and 2 xref: EMAPA:17478 ! mesenchyme of interdigital region between digits 1 and 2 of hindlimb xref: EHDAA2:0000858 ! interdigital region between toes 1 and 2 mesenchyme synonym: "interdigital region between toes 1 and 2 mesenchyme" EXACT [EHDAA2:0000858] def: "An interdigital region mesenchyme that is part of a interdigital region between pedal digits 1 and 2." [OBOL:automatic] [Term] id: UBERON:0009591 name: mesenchyme of interdigital region between pedal digits 2 and 3 relationship: part_of UBERON:0006041 {source="EMAPA"} ! interdigital region between toes 2 and 3 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006041 ! interdigital region between toes 2 and 3 xref: EMAPA:17481 ! mesenchyme of interdigital region between digits 2 and 3 of hindlimb xref: EHDAA2:0000861 ! interdigital region between toes 2 and 3 mesenchyme synonym: "interdigital region between toes 2 and 3 mesenchyme" EXACT [EHDAA2:0000861] def: "An interdigital region mesenchyme that is part of a interdigital region between pedal digits 2 and 3." [OBOL:automatic] [Term] id: UBERON:0009592 name: mesenchyme of interdigital region between pedal digits 3 and 4 relationship: part_of UBERON:0006044 {source="EMAPA"} ! interdigital region between toes 3 and 4 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006044 ! interdigital region between toes 3 and 4 xref: EMAPA:17484 ! mesenchyme of interdigital region between digits 3 and 4 of hindlimb xref: EHDAA2:0000864 ! interdigital region between toes 3 and 4 mesenchyme synonym: "interdigital region between toes 3 and 4 mesenchyme" EXACT [EHDAA2:0000864] def: "An interdigital region mesenchyme that is part of a interdigital region between pedal digits 3 and 4." [OBOL:automatic] [Term] id: UBERON:0009593 name: mesenchyme of interdigital region between pedal digits 4 and 5 relationship: part_of UBERON:0006047 {source="EMAPA"} ! interdigital region between toes 4 and 5 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006047 ! interdigital region between toes 4 and 5 xref: EMAPA:17487 ! mesenchyme of interdigital region between digits 4 and 5 of hindlimb xref: EHDAA2:0000867 ! interdigital region between toes 4 and 5 mesenchyme synonym: "interdigital region between toes 4 and 5 mesenchyme" EXACT [EHDAA2:0000867] def: "An interdigital region mesenchyme that is part of a interdigital region between pedal digits 4 and 5." [OBOL:automatic] [Term] id: UBERON:0009596 name: mesenchyme of interdigital region between digits 1 and 2 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006016 ! interdigital region between digits 1 and 2 def: "An interdigital region mesenchyme that is part of a interdigital region between digits 1 and 2." [OBOL:automatic] [Term] id: UBERON:0009597 name: mesenchyme of interdigital region between digits 2 and 3 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006019 ! interdigital region between digits 2 and 3 def: "An interdigital region mesenchyme that is part of a interdigital region between digits 2 and 3." [OBOL:automatic] [Term] id: UBERON:0009598 name: mesenchyme of interdigital region between digits 3 and 4 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006022 ! interdigital region between digits 3 and 4 def: "An interdigital region mesenchyme that is part of a interdigital region between digits 3 and 4." [OBOL:automatic] [Term] id: UBERON:0009599 name: mesenchyme of interdigital region between digits 4 and 5 intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0006025 ! interdigital region between digits 4 and 5 def: "An interdigital region mesenchyme that is part of a interdigital region between digits 4 and 5." [OBOL:automatic] [Term] id: UBERON:0009600 name: mesenchyme of interdigital region of manus intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0002398 ! manus synonym: "mesenchyme of interdigital region of forelimb" EXACT [] def: "An interdigital region mesenchyme that is part of a manus." [OBOL:automatic] relationship: part_of UBERON:0006013 {is_inferred="true", source="reference_0000032"} ! interdigital region between manual digits [Term] id: UBERON:0009601 name: mesenchyme of interdigital region of pes intersection_of: UBERON:0009585 ! interdigital region mesenchyme intersection_of: part_of UBERON:0002387 ! pes synonym: "mesenchyme of interdigital region of hindlimb" EXACT [] def: "An interdigital region mesenchyme that is part of a pes." [OBOL:automatic] relationship: part_of UBERON:0006014 {is_inferred="true", source="reference_0000032"} ! interdigital region between pedal digits [Term] id: UBERON:0006086 name: stria medullaris def: "The major afferent track to the habenula from the telencephalon (particularly in the septal side) in all vertebrates[Butler and Hodos]." [ISBN10:0471888893] synonym: "stria habenularis" EXACT [NIF_GrossAnatomy:birnlex_1066] synonym: "stria medullaris of thalamus" EXACT [NIF_GrossAnatomy:birnlex_1066, FMA:62080] synonym: "stria medullaris thalami" EXACT PLURAL [NIF_GrossAnatomy:birnlex_1066] synonym: "stria medullaris thalamica" EXACT [NIF_GrossAnatomy:birnlex_1066] synonym: "stria medullaris (wenzel - wenzel)" EXACT [NIF_GrossAnatomy:birnlex_1066] xref: FMA:62080 ! stria medullaris of thalamus xref: NIF_GrossAnatomy:birnlex_1066 ! Stria medullaris xref: BM:Die-SM ! stria medullaris of thalamus is_a: UBERON:0013199 {source="FMA"} ! stria of neuraxis relationship: part_of UBERON:0001893 ! telencephalon relationship: present_in_taxon NCBITaxon:7742 {source="ISBN10:0471888893"} ! Vertebrata relationship: overlaps UBERON:0001904 ! habenula xref: SCTID:362368004 ! Entire stria medullaris property_value: external_definition "Stria medullaris of thalamus is a slender fiber bundle on the dorsal surface of the diencephalon which terminates posteriorly in the habenular nuclei[FMA:62080]." xsd:string {source="FMA:62080"} [Term] id: UBERON:0006087 name: internal arcuate fiber bundle synonym: "arcuate fibers medial lemniscus" EXACT [NIF_GrossAnatomy:birnlex_1091] synonym: "internal arcuate fibers" EXACT [NIF_GrossAnatomy:birnlex_1091] synonym: "internal arcuate fibers" EXACT [FMA:72629] synonym: "internal arcuate fibres" EXACT [FMA:72629] synonym: "internal arcuate tract" EXACT [FMA:72629] xref: FMA:72629 ! internal arcuate tract xref: NIF_GrossAnatomy:birnlex_1091 ! Internal arcuate fiber bundle is_a: UBERON:0000122 ! nerve fiber bundle relationship: part_of UBERON:0001896 ! medulla oblongata synonym: "fibrae arcuatae internae" EXACT LATIN [FMA:TA, FMA:72629] [Term] id: UBERON:0006088 name: inferior parietal cortex def: "Component of the parietal lobe. The inferior parietal cortex label includes the inferior parietal gyrus and the angular gyrus and lies inferior to the superior parietal gyrus. The rostral and caudal boundaries were the supramarginal gyrus and the parieto-occipital incisure respectively. The medial and lateral boundaries were the superior parietal gyrus and the middle temporal gyrus respectively (Christine Fennema-Notestine)." [NIF_GrossAnatomy:birnlex_1194] synonym: "inferior parietal cortex" EXACT [NIF_GrossAnatomy:birnlex_1194] synonym: "inferior parietal lobule" EXACT [NIF_GrossAnatomy:birnlex_1194] synonym: "inferior parietal lobule" EXACT [FMA:77536] xref: FMA:77536 ! inferior parietal lobule xref: NIF_GrossAnatomy:birnlex_1194 ! Inferior parietal cortex xref: EFO:0001951 ! inferior parietal lobule is_a: UBERON:0002791 ! regional part of telencephalon is_a: UBERON:0003022 ! lobe parts of cerebral cortex xref: SCTID:362336007 ! Entire inferior parietal lobule [Term] id: UBERON:0006089 name: dorsal external arcuate fiber bundle synonym: "dorsal external arcuate fiber bundle" EXACT [NIF_GrossAnatomy:birnlex_1250] synonym: "dorsal external arcuate fibers" EXACT [NIF_GrossAnatomy:birnlex_1250] synonym: "dorsal superficial arcuate fibers" EXACT [NIF_GrossAnatomy:birnlex_1250] synonym: "external arcuate fibers" EXACT [NIF_GrossAnatomy:birnlex_1250] synonym: "dorsal external arcuate fibers" EXACT [FMA:72630] synonym: "dorsal superficial arcuate fibers" EXACT [FMA:72630] synonym: "dorsal external arcuate tract" EXACT [FMA:72630] xref: FMA:72630 ! dorsal external arcuate tract xref: NIF_GrossAnatomy:birnlex_1250 ! Dorsal external arcuate fiber bundle is_a: UBERON:0000122 ! nerve fiber bundle relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0006090 name: glossopharyngeal nerve fiber bundle synonym: "central part of glossopharyngeal nerve" EXACT [NIF_GrossAnatomy:birnlex_1274] synonym: "glossopharyngeal nerve fiber bundle" EXACT [NIF_GrossAnatomy:birnlex_1274] synonym: "glossopharyngeal nerve fibers" EXACT [NIF_GrossAnatomy:birnlex_1274] synonym: "ninth cranial nerve fibers" EXACT [NIF_GrossAnatomy:birnlex_1274] synonym: "central part of glossopharyngeal nerve" EXACT [FMA:72627] synonym: "glossopharyngeal nerve fibers" EXACT [FMA:72627] synonym: "ninth cranial nerve fibers" EXACT [FMA:72627] synonym: "glossopharyngeal nerve tract" EXACT [FMA:72627] xref: FMA:72627 ! glossopharyngeal nerve tract xref: NIF_GrossAnatomy:birnlex_1274 ! Glossopharyngeal nerve fiber bundle is_a: UBERON:0002678 ! regional part of medulla oblongata relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0006091 name: inferior horn of the lateral ventricle def: "The part of the lateral ventricle extending downward and anteriorly in the temporal lobe." [NIF_GrossAnatomy:birnlex_1292] synonym: "inferior horn of the lateral ventricle" EXACT [NIF_GrossAnatomy:birnlex_1292] synonym: "temporal horn of lateral ventricle" EXACT [NIF_GrossAnatomy:birnlex_1292] synonym: "inferior horn of lateral ventricle" EXACT [FMA:83701] xref: FMA:83701 ! temporal horn of lateral ventricle xref: NIF_GrossAnatomy:birnlex_1292 ! Inferior horn of the lateral ventricle is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002285 ! telencephalic ventricle synonym: "cornu inferius ventriculi lateralis" EXACT LATIN [FMA:TA, FMA:83701] xref: SCTID:362315005 ! Entire inferior horn of lateral ventricle [Term] id: UBERON:0006092 name: cuneus cortex def: "Component of the occipital lobe. The rostral boundary was the first coronal slice above the calcarine sulcus where the cuneus cortex becomes visible whereas the caudal boundary was the last slice where the calcarine sulcus was visualized. The medial boundary was the most medial portion of the occipital and parietal cortices. The superio-lateral boundary was the parieto-occipital fissure whereas the inferolateral boundary was the pericalcarine cortex (Christine Fennema-Notestine)." [NIF_GrossAnatomy:birnlex_1396] synonym: "cuneate lobule" EXACT [NIF_GrossAnatomy:birnlex_1396] synonym: "cuneus" EXACT [NIF_GrossAnatomy:birnlex_1396] synonym: "cuneus cortex" EXACT [NIF_GrossAnatomy:birnlex_1396] synonym: "cuneus gyrus" EXACT [NIF_GrossAnatomy:birnlex_1396] synonym: "cuneus of hemisphere" EXACT [NIF_GrossAnatomy:birnlex_1396] synonym: "cuneate lobule" EXACT [FMA:61903] synonym: "cuneus gyrus" EXACT [FMA:61903] synonym: "cuneus of hemisphere" EXACT [FMA:61903] xref: FMA:61903 ! cuneus xref: NIF_GrossAnatomy:birnlex_1396 ! Cuneus cortex is_a: UBERON:0002791 ! regional part of telencephalon is_a: UBERON:0003022 ! lobe parts of cerebral cortex relationship: part_of UBERON:0001950 ! neocortex relationship: part_of UBERON:0002021 ! occipital lobe xref: SCTID:279199007 ! Entire cuneus [Term] id: UBERON:0006093 name: precuneus cortex def: "Component of the pareital lobe. The rostral boundary was the posterior extent of the paracentral lobule whereas the caudal boundary was the lingual gyrus. The medial and lateral boundaries were the parieto-occipital fissure and the superior parietal gyrus respectively (Christine Fennema-Notestine)." [NIF_GrossAnatomy:birnlex_1446] synonym: "precuneate lobule" EXACT [NIF_GrossAnatomy:birnlex_1446] synonym: "precuneus" EXACT [NIF_GrossAnatomy:birnlex_1446] synonym: "precuneus cortex" EXACT [NIF_GrossAnatomy:birnlex_1446] synonym: "quadrate lobule" EXACT [NIF_GrossAnatomy:birnlex_1446] synonym: "precuneate lobule" EXACT [FMA:61900] synonym: "quadrate lobule" EXACT [FMA:61900] xref: FMA:61900 ! precuneus xref: NIF_GrossAnatomy:birnlex_1446 ! Precuneus cortex is_a: UBERON:0002791 ! regional part of telencephalon is_a: UBERON:0003022 ! lobe parts of cerebral cortex relationship: part_of UBERON:0001872 ! parietal lobe relationship: part_of UBERON:0001950 ! neocortex xref: SCTID:279200005 ! Entire precuneus [Term] id: UBERON:0006094 name: superior parietal cortex def: "Copmonent of the parietal lobe. The rostral and caudal boundaries of the superior parietal cortex were the precentral gyrus and lateral occipital cortex respectively. The medial and lateral boundaries were the precuneus and/or cuneus cortex and the infererior parietal cortex respectively (Christine Fennema-Notestine)." [NIF_GrossAnatomy:birnlex_1450] synonym: "superior parietal cortex" EXACT [NIF_GrossAnatomy:birnlex_1450] synonym: "superior parietal gyrus" EXACT [NIF_GrossAnatomy:birnlex_1450] synonym: "superior parietal lobule" EXACT [NIF_GrossAnatomy:birnlex_1450] synonym: "superior portion of parietal gyrus" EXACT [NIF_GrossAnatomy:birnlex_1450] synonym: "superior parietal gyrus" EXACT [FMA:61899] synonym: "superior portion of parietal gyrus" EXACT [FMA:61899] xref: FMA:61899 ! superior parietal lobule xref: NIF_GrossAnatomy:birnlex_1450 ! Superior parietal cortex is_a: UBERON:0002791 ! regional part of telencephalon is_a: UBERON:0003022 ! lobe parts of cerebral cortex relationship: part_of UBERON:0001872 ! parietal lobe relationship: part_of UBERON:0001950 ! neocortex xref: SCTID:279168006 ! Entire superior parietal lobule [Term] id: UBERON:0006097 name: ventral external arcuate fiber bundle synonym: "ventral external arcuate fiber bundle" EXACT [NIF_GrossAnatomy:birnlex_1628] synonym: "ventral external arcuate fibers" EXACT [NIF_GrossAnatomy:birnlex_1628] synonym: "ventral external arcuate fibers" EXACT [FMA:72631] synonym: "ventral external arcuate tract" EXACT [FMA:72631] xref: FMA:72631 ! ventral external arcuate tract xref: NIF_GrossAnatomy:birnlex_1628 ! Ventral external arcuate fiber bundle is_a: UBERON:0000122 ! nerve fiber bundle is_a: UBERON:0002678 ! regional part of medulla oblongata relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0013529 name: Brodmann area def: "A Brodmann area is a region of the cerebral cortex defined based on its cytoarchitectonics, or structure and organization of cells." [Wikipedia:Brodmann_area] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000956 {source="FMA", source="Wikipedia"} ! cerebral cortex xref: FMA:68596 ! brodmann area xref: NIF_GrossAnatomy:birnlex_1731 ! Brodmann partition scheme region xref: WikipediaCategory:Brodmann_areas xref: SCTID:384717008 ! Brodmann area [Term] id: UBERON:0006099 name: Brodmann (1909) area 1 def: "." [NIF_GrossAnatomy:birnlex_1732] synonym: "Area postcentralis intermedia" EXACT [NIF_GrossAnatomy:birnlex_1732] synonym: "B09-1" EXACT [NIF_GrossAnatomy:birnlex_1732] synonym: "Brodmann area 1" EXACT [NIF_GrossAnatomy:birnlex_1732] synonym: "BA1" EXACT ABBREVIATION [] synonym: "area 1 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1732] synonym: "Brodmann (1909) area 1" EXACT [NIF_GrossAnatomy:birnlex_1732] synonym: "intermediate postcentral" EXACT [NIF_GrossAnatomy:birnlex_1732] synonym: "area 1 of Brodmann" EXACT [FMA:68597] synonym: "Brodmann's area 1" EXACT [FMA:68597] synonym: "intermediate postcentral area" EXACT [FMA:68597] xref: FMA:68597 ! Brodmann area 1 xref: NIF_GrossAnatomy:birnlex_1732 ! Brodmann (1909) area 1 is_a: UBERON:0013529 {source="FMA"} ! Brodmann area relationship: part_of UBERON:0000956 ! cerebral cortex [Term] id: UBERON:0006100 name: Brodmann (1909) area 3 def: "." [NIF_GrossAnatomy:birnlex_1734] synonym: "Area postcentralis oralis" EXACT [NIF_GrossAnatomy:birnlex_1734] synonym: "B09-3" EXACT [NIF_GrossAnatomy:birnlex_1734] synonym: "Brodmann area 3" EXACT [NIF_GrossAnatomy:birnlex_1734] synonym: "BA3" EXACT ABBREVIATION [] synonym: "area 3 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1734] synonym: "Brodmann (1909) area 3" EXACT [NIF_GrossAnatomy:birnlex_1734] synonym: "rostral postcentral" EXACT [NIF_GrossAnatomy:birnlex_1734] synonym: "area 3 of Brodmann" EXACT [FMA:68599] synonym: "Brodmann's area 3" EXACT [FMA:68599] synonym: "rostral postcentral area" EXACT [FMA:68599] xref: FMA:68599 ! Brodmann area 3 xref: NIF_GrossAnatomy:birnlex_1734 ! Brodmann (1909) area 3 is_a: UBERON:0013529 {source="FMA"} ! Brodmann area relationship: part_of UBERON:0000956 ! cerebral cortex [Term] id: UBERON:0006101 name: Brodmann (1909) area 24 def: "." [NIF_GrossAnatomy:birnlex_1755] synonym: "area cingularis anterior ventralis" EXACT [NIF_GrossAnatomy:birnlex_1755] synonym: "B09-24" EXACT [NIF_GrossAnatomy:birnlex_1755] synonym: "Brodmann area 24" EXACT [NIF_GrossAnatomy:birnlex_1755] synonym: "BA24" EXACT ABBREVIATION [] synonym: "area 24 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1755] synonym: "Brodmann (1909) area 24" EXACT [NIF_GrossAnatomy:birnlex_1755] synonym: "ventral anterior cingulate" EXACT [NIF_GrossAnatomy:birnlex_1755] synonym: "area 24 of Brodmann" EXACT [FMA:68621] xref: FMA:68621 ! Brodmann area 24 xref: NIF_GrossAnatomy:birnlex_1755 ! Brodmann (1909) area 24 is_a: UBERON:0013529 {source="FMA"} ! Brodmann area relationship: part_of UBERON:0000956 ! cerebral cortex [Term] id: UBERON:0006102 name: Brodmann (1909) area 35 synonym: "Area perirhinalis" EXACT [NIF_GrossAnatomy:birnlex_1768] synonym: "B09-35" EXACT [NIF_GrossAnatomy:birnlex_1768] synonym: "Brodmann area 35" EXACT [NIF_GrossAnatomy:birnlex_1768] synonym: "BA35" EXACT ABBREVIATION [] synonym: "Brodmann area 35, perirhinal" EXACT [NIF_GrossAnatomy:birnlex_1768] synonym: "Brodmann.35" EXACT [NIF_GrossAnatomy:birnlex_1768] synonym: "area 35 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1768] synonym: "Brodmann (1909) area 35" EXACT [NIF_GrossAnatomy:birnlex_1768] synonym: "area 35 of Brodmann" EXACT [FMA:68632] synonym: "Brodmann's area 35" EXACT [FMA:68632] synonym: "perirhinal area 35" EXACT [FMA:68632] xref: FMA:68632 ! Brodmann area 35 xref: NIF_GrossAnatomy:birnlex_1768 ! Brodmann (1909) area 35 xref: BTO:0004356 ! Brodmann area 35 is_a: UBERON:0013529 {source="FMA"} ! Brodmann area xref: SCTID:384790006 ! Entire Brodmann area 35, perirhinal [Term] id: UBERON:0006104 name: Brodmann (1909) area 36 synonym: "Area ectorhinalis" EXACT [NIF_GrossAnatomy:birnlex_1769] synonym: "B09-36" EXACT [NIF_GrossAnatomy:birnlex_1769] synonym: "Brodmann area 36" EXACT [NIF_GrossAnatomy:birnlex_1769] synonym: "BA36" EXACT ABBREVIATION [] synonym: "Brodmann.36" EXACT [NIF_GrossAnatomy:birnlex_1769] synonym: "area 36 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1769] synonym: "Brodmann (1909) area 36" EXACT [NIF_GrossAnatomy:birnlex_1769] synonym: "ectorhinal" EXACT [NIF_GrossAnatomy:birnlex_1769] synonym: "area 36 of Brodmann" EXACT [FMA:68633] synonym: "ectorhinal area 36" EXACT [FMA:68633] xref: FMA:68633 ! Brodmann area 36 xref: NIF_GrossAnatomy:birnlex_1769 ! Brodmann (1909) area 36 xref: BTO:0004357 ! Brodmann area 36 is_a: UBERON:0013529 {source="FMA"} ! Brodmann area [Term] id: UBERON:0013528 name: Brodmann (1909) area 11 def: "Brodmann area 11 is one of Brodmann's cytologically defined regions of the brain. It is involved in planning, reasoning, and decision making." [Wikipedia:Brodmann_area_11] synonym: "area 11 of brodmann" RELATED [Wikipedia:Brodmann_area_11] synonym: "prefrontal area 11" RELATED [Wikipedia:Brodmann_area_11] synonym: "area 11 of brodmann" EXACT [FMA:68608] synonym: "medial orbital area" EXACT [FMA:68608] synonym: "area praefrontalis" BROAD [NIF_GrossAnatomy:birnlex_1742] synonym: "B09-11" EXACT [NIF_GrossAnatomy:birnlex_1742] synonym: "Brodmann area 11, prefrontal" EXACT [NIF_GrossAnatomy:birnlex_1742] synonym: "area 11 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1742] synonym: "brodmann (1909) area 11" EXACT [NIF_GrossAnatomy:birnlex_1742] is_a: UBERON:0013529 {source="FMA"} ! Brodmann area xref: FMA:68608 ! brodmann area 11 xref: NIF_GrossAnatomy:birnlex_1742 ! Brodmann (1909) area 11 [Term] id: UBERON:0004717 name: Brodmann (1909) area 29 def: "Brodmann area 29, also known as granular retrolimbic area 29 or granular retrosplenial cortex, is a cytoarchitecturally defined portion of the retrosplenial region of the cerebral cortex. In the human it is a narrow band located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the ectosplenial area 26 and externally by the agranular retrolimbic area 30 (Brodmann-1909)." [Wikipedia:Brodmann_area_29] synonym: "granular retrolimbic area 29" RELATED [BTO:0003978, Wikipedia:Brodmann_area_29] synonym: "area 29 of brodmann" EXACT [FMA:68626] synonym: "brodmann's area 29" EXACT [FMA:68626] synonym: "Area retrolimbica granularis" EXACT [NIF_GrossAnatomy:birnlex_1763] synonym: "B09-29" EXACT [NIF_GrossAnatomy:birnlex_1763] synonym: "Brodmann area 29, granular retrolimbic" EXACT [NIF_GrossAnatomy:birnlex_1763] synonym: "area 29 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1763] synonym: "brodmann (1909) area 29" EXACT [NIF_GrossAnatomy:birnlex_1763] synonym: "Brodmann area 29" EXACT [FMA:68626] xref: Wikipedia:Brodmann_area_29 ! brodmann area 29 xref: BTO:0003978 ! Brodmann area 29 xref: FMA:68626 ! Brodmann area 29 xref: NIF_GrossAnatomy:birnlex_1763 ! Brodmann (1909) area 29 is_a: UBERON:0013529 {source="FMA"} ! Brodmann area property_value: external_definition "A cytoarchitecturally defined portion of the retrosplenial region of the cerebral cortex. In the human it is a narrow band located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the ectosplenial area 26 and externally by the agranular retrolimbic area 30[BTO:0003978]." xsd:string {source="BTO:0003978"} [Term] id: UBERON:0004718 name: Brodmann (1909) area 26 def: "." [Wikipedia:Brodmann_area_26] synonym: "Area ectosplenialis" EXACT [NIF_GrossAnatomy:birnlex_1757] synonym: "B09-26" EXACT [NIF_GrossAnatomy:birnlex_1757] synonym: "Brodmann area 26, ectosplenial" EXACT [NIF_GrossAnatomy:birnlex_1757] synonym: "area 26 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1757] synonym: "brodmann (1909) area 26" EXACT [NIF_GrossAnatomy:birnlex_1757] synonym: "ectosplenial area 26" RELATED [BTO:0003979, Wikipedia:Brodmann_area_26] synonym: "area 26 of brodmann" EXACT [FMA:68623] synonym: "ectosplenial area" EXACT [FMA:68623] synonym: "Brodmann area 26" EXACT [FMA:68623] xref: Wikipedia:Brodmann_area_26 ! brodmann area 26 xref: BTO:0003979 ! Brodmann area 26 xref: FMA:68623 ! Brodmann area 26 xref: NIF_GrossAnatomy:birnlex_1757 ! Brodmann (1909) area 26 is_a: UBERON:0013529 {source="FMA"} ! Brodmann area property_value: external_definition "In the human this area is called ectosplenial area 26. It is a cytoarchitecturally defined portion of the retrosplenial region of the cerebral cortex. It is a narrow band located in the isthmus of cingulate gyrus adjacent to the fasciolar gyrus internally. It is bounded externally by the granular retrolimbic area 29[BTO:0003979]." xsd:string {source="BTO:0003979"} [Term] id: UBERON:0013533 name: Brodmann (1909) area 2 synonym: "Area postcentralis caudalis" EXACT [NIF_GrossAnatomy:birnlex_1733] synonym: "B09-2" EXACT [NIF_GrossAnatomy:birnlex_1733] synonym: "Brodmann area 2, caudal postcentral" EXACT [NIF_GrossAnatomy:birnlex_1733] synonym: "area 2 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1733] synonym: "brodmann (1909) area 2" EXACT [NIF_GrossAnatomy:birnlex_1733] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1733 ! Brodmann (1909) area 2 synonym: "Area 2 of Brodmann" EXACT [FMA:68598] synonym: "Brodmann's area 2" EXACT [FMA:68598] synonym: "Caudal postcentral area" EXACT [FMA:68598] xref: FMA:68598 ! Brodmann area 2 synonym: "Brodmann area 2" EXACT [FMA:68598] [Term] id: UBERON:0013535 name: Brodmann (1909) area 4 synonym: "Area gigantopyramidalis" EXACT [NIF_GrossAnatomy:birnlex_1735] synonym: "B09-4" EXACT [NIF_GrossAnatomy:birnlex_1735] synonym: "Brodmann area 4, gigantopyramidal" EXACT [NIF_GrossAnatomy:birnlex_1735] synonym: "area 4 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1735] synonym: "brodmann (1909) area 4" EXACT [NIF_GrossAnatomy:birnlex_1735] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1735 ! Brodmann (1909) area 4 synonym: "Area 4 of Brodmann" EXACT [FMA:68600] synonym: "Brodmann's area 4" EXACT [FMA:68600] synonym: "Giant pyramidal area" EXACT [FMA:68600] xref: FMA:68600 ! Brodmann area 4 synonym: "Brodmann area 4" EXACT [FMA:68600] [Term] id: UBERON:0013538 name: Brodmann (1909) area 7 def: "Brodmann area 7 is one of Brodmann's cytologically defined regions of the brain. It is involved in locating objects in space. It serves as a point of convergence between vision and proprioception to determine where objects are in relation to parts of the body." [Wikipedia:Brodmann_area_7] synonym: "Area parietalis superior" EXACT LATIN [Wikipedia:Brodmann_area_7] synonym: "Area parietalis superior" EXACT [NIF_GrossAnatomy:birnlex_1738] synonym: "B09-7" EXACT [NIF_GrossAnatomy:birnlex_1738] synonym: "Brodmann area 7, superior parietal" EXACT [NIF_GrossAnatomy:birnlex_1738] synonym: "area 7 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1738] synonym: "brodmann (1909) area 7" EXACT [NIF_GrossAnatomy:birnlex_1738] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1738 ! Brodmann (1909) area 7 xref: FMA:68604 ! Brodmann area 7 synonym: "Brodmann area 7" EXACT [FMA:68604] [Term] id: UBERON:0013539 name: Brodmann (1909) area 8 def: "Brodmann area 8 is one of Brodmann's cytologically defined regions of the brain. It is involved in planning complex movements." [Wikipedia:Brodmann_area_8] synonym: "Area frontalis intermedia" EXACT LATIN [Wikipedia:Brodmann_area_8] synonym: "Area frontalis intermedia" EXACT [NIF_GrossAnatomy:birnlex_1739] synonym: "B09-8" EXACT [NIF_GrossAnatomy:birnlex_1739] synonym: "Brodmann area 8, intermediate frontal" EXACT [NIF_GrossAnatomy:birnlex_1739] synonym: "area 8 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1739] synonym: "brodmann (1909) area 8" EXACT [NIF_GrossAnatomy:birnlex_1739] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1739 ! Brodmann (1909) area 8 synonym: "Area 8 of Brodmann" EXACT [FMA:68605] synonym: "Intermediate frontal area" EXACT [FMA:68605] xref: FMA:68605 ! Brodmann area 8 synonym: "Brodmann area 8" EXACT [FMA:68605] [Term] id: UBERON:0013540 name: Brodmann (1909) area 9 def: "" [Wikipedia:Brodmann_area_9] synonym: "Area frontalis granularis" EXACT LATIN [Wikipedia:Brodmann_area_9] synonym: "Area frontalis granularis" EXACT [NIF_GrossAnatomy:birnlex_1740] synonym: "B09-9" EXACT [NIF_GrossAnatomy:birnlex_1740] synonym: "Brodmann area 9, granular frontal" EXACT [NIF_GrossAnatomy:birnlex_1740] synonym: "area 9 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1740] synonym: "brodmann (1909) area 9" EXACT [NIF_GrossAnatomy:birnlex_1740] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1740 ! Brodmann (1909) area 9 synonym: "Area 9 of Brodmann" EXACT [FMA:68606] synonym: "Granular frontal area" EXACT [FMA:68606] xref: FMA:68606 ! Brodmann area 9 synonym: "Brodmann area 9" EXACT [FMA:68606] [Term] id: UBERON:0013541 name: Brodmann (1909) area 10 synonym: "Area frontopolaris" EXACT [NIF_GrossAnatomy:birnlex_1741] synonym: "B09-10" EXACT [NIF_GrossAnatomy:birnlex_1741] synonym: "Brodmann area 10, frontoplar" EXACT [NIF_GrossAnatomy:birnlex_1741] synonym: "Brodmann.10" EXACT [NIF_GrossAnatomy:birnlex_1741] synonym: "area 10 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1741] synonym: "brodmann (1909) area 10" EXACT [NIF_GrossAnatomy:birnlex_1741] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1741 ! Brodmann (1909) area 10 synonym: "Area 10 of Brodmann" EXACT [FMA:68607] synonym: "Lateral orbital area" EXACT [FMA:68607] xref: FMA:68607 ! Brodmann area 10 synonym: "Brodmann area 10" EXACT [FMA:68607] [Term] id: UBERON:0013543 alt_id: UBERON:0013530 name: Brodmann (1909) area 12 def: "Brodmann area 12 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It occupies the most rostral portion of the frontal lobe. Brodmann-1909 did not regard it as homologous, either topographically or cytoarchitecturally, to rostral area 12 of the human. Distinctive features (Brodmann-1905): a quite distinct internal granular layer (IV) separates slender pyramidal cells of the external pyramidal layer (III) and the internal pyramidal layer (V); the multiform layer (VI) is expanded, contains widely dispersed spindle cells and merges gradually with the underlying cortical white matter; all cells, including the pyramidal cells of the external and internal pyramidal layers are inordinately small; the internal pyramidal layer (V) also contains spindle cells in groups of two to five located close to its border with the internal granular layer (IV)." [Wikipedia:Brodmann_area_12] synonym: "Brodmann area 12" EXACT [FMA:68609] synonym: "area 12 of brodmann" EXACT [FMA:68609] synonym: "frontopolar area" EXACT [FMA:68609] synonym: "area praefrontalis" BROAD [NIF_GrossAnatomy:birnlex_1743] synonym: "B09-12" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "Brodmann area 12, prefrontal" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "area 12 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "brodmann (1909) area 12" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "Area praefrontalis" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "B09-12" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "Brodmann area 12, prefrontal" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "area 12 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1743] synonym: "brodmann (1909) area 12" EXACT [NIF_GrossAnatomy:birnlex_1743] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1743 ! Brodmann (1909) area 12 xref: FMA:68609 ! brodmann area 12 [Term] id: UBERON:0013544 name: Brodmann (1909) area 13 def: "Brodmann area 13 is a subdivision of the cerebral cortex as defined on the guenon monkey and on the basis of cytoarchitecture. Brodmann area 13 is found in humans, however it seems to act as a bridge between the lateral and medial layers of the brain. Thus it is sometimes misidentified as not being a Brodmann area." [Wikipedia:Brodmann_area_13] synonym: "B09-13" EXACT [NIF_GrossAnatomy:birnlex_1744] synonym: "area 13 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1744] synonym: "brodmann (1909) area 13" EXACT [NIF_GrossAnatomy:birnlex_1744] synonym: "Brodmann area 13" EXACT [FMA:68610] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1744 ! Brodmann (1909) area 13 xref: FMA:68610 ! Brodmann area 13 synonym: "Brodmann area 13" EXACT [FMA:68610] [Term] id: UBERON:0013545 name: Brodmann (1909) area 14 synonym: "B09-14" EXACT [NIF_GrossAnatomy:birnlex_1745] synonym: "area 14 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1745] synonym: "brodmann (1909) area 14" EXACT [NIF_GrossAnatomy:birnlex_1745] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1745 ! Brodmann (1909) area 14 xref: FMA:68611 ! Brodmann area 14 synonym: "Brodmann area 14" EXACT [FMA:68611] [Term] id: UBERON:0013546 name: Brodmann (1909) area 15 def: "Brodmann Area 15 is one of Brodmann's subdivisions of the cerebral cortex in the brain. Area 15 was defined by Brodmann in the guenon monkey, but he found no equivalent structure in humans. However, functional imaging experiments have found structures that may be homologous." [Wikipedia:Brodmann_area_15] synonym: "B09-15" EXACT [NIF_GrossAnatomy:birnlex_1746] synonym: "area 15 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1746] synonym: "brodmann (1909) area 15" EXACT [NIF_GrossAnatomy:birnlex_1746] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1746 ! Brodmann (1909) area 15 xref: FMA:68612 ! Brodmann area 15 synonym: "Brodmann area 15" EXACT [FMA:68612] [Term] id: UBERON:0013547 name: Brodmann (1909) area 16 def: "Brodmann area 16 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It is a relatively undifferentiated cortical area that Brodmann regarded as part of the insula because of the relation of its innermost multiform layer (VI) with the claustrum (VICl). The laminar organization of cortex is almost totally lacking. The molecular layer (I) is wide as in area 15 of Brodmann-1905. The space between layer I and layer VI is composed of a mixture of pyramidal cells and spindle cells with no significant number of granule cells. Pyramidal cells clump in the outer part to form glomeruli similar to those seen in some of the primary olfactory areas (Brodmann-1905). This term also refers to an area known as peripaleocortical claustral - a cytoarchitecturally defined (agranular) portion of the insula at its rostral extreme where it approaches most closely the claustrum and the prepyriform area (Stephan-76)." [Wikipedia:Brodmann_area_16] synonym: "B09-16" EXACT [NIF_GrossAnatomy:birnlex_1747] synonym: "area 16 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1747] synonym: "brodmann (1909) area 16" EXACT [NIF_GrossAnatomy:birnlex_1747] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1747 ! Brodmann (1909) area 16 synonym: "Area 16 of Brodmann" EXACT [FMA:68613] xref: FMA:68613 ! Brodmann area 16 synonym: "Brodmann area 16" EXACT [FMA:68613] [Term] id: UBERON:0013550 name: Brodmann (1909) area 19 synonym: "Area peristriata" EXACT [NIF_GrossAnatomy:birnlex_1750] synonym: "B09-19" EXACT [NIF_GrossAnatomy:birnlex_1750] synonym: "Brodmann area 19, peristriate" EXACT [NIF_GrossAnatomy:birnlex_1750] synonym: "area 19 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1750] synonym: "brodmann (1909) area 19" EXACT [NIF_GrossAnatomy:birnlex_1750] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1750 ! Brodmann (1909) area 19 synonym: "Area 19 of Brodmann" EXACT [FMA:68616] synonym: "Brodmann's area 19" EXACT [FMA:68616] synonym: "Preoccipital area" EXACT [FMA:68616] xref: FMA:68616 ! Brodmann area 19 synonym: "Brodmann area 19" EXACT [FMA:68616] [Term] id: UBERON:0013551 name: Brodmann (1909) area 20 synonym: "Area temporalis inferior" EXACT [NIF_GrossAnatomy:birnlex_1751] synonym: "B09-20" EXACT [NIF_GrossAnatomy:birnlex_1751] synonym: "Brodmann area 20, inferior temporal" EXACT [NIF_GrossAnatomy:birnlex_1751] synonym: "area 20 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1751] synonym: "brodmann (1909) area 20" EXACT [NIF_GrossAnatomy:birnlex_1751] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1751 ! Brodmann (1909) area 20 synonym: "Area 20 of Brodmann" EXACT [FMA:68617] synonym: "Inferior temporal area" EXACT [FMA:68617] xref: FMA:68617 ! Brodmann area 20 synonym: "Brodmann area 20" EXACT [FMA:68617] [Term] id: UBERON:0004685 name: middle temporal area synonym: "middle temporal area" EXACT [NIF_GrossAnatomy:nlx_anat_20090308] synonym: "middle temporal area" EXACT [FMA:68618] xref: NIF_GrossAnatomy:nlx_anat_20090308 ! Middle temporal area xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e8/Brodmann_area_21.png/200px-Brodmann_area_21.png is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Brodmann_area_21.png [Term] id: UBERON:0013552 name: Brodmann (1909) area 21 def: "Brodmann area 21, or BA21, is part of the temporal cortex in the human brain. The region encompasses most of the lateral temporal cortex, a region believed to play a part in auditory processing and language. Language function is left lateralized in most individuals. BA21 is superior to BA20 and inferior to BA40 and BA41. This area is also known as middle temporal area 21. It is a subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. In the human it corresponds approximately to the middle temporal gyrus. It is bounded rostrally by the temporopolar area 38 (H), ventrally by the inferior temporal area 20, caudally by the occipitotemporal area 37 (H), and dorsally by the superior temporal area 22 (Brodmann-1909). [WP,unvetted]." [Wikipedia:Brodmann_area_21] synonym: "area 21 of Brodmann" EXACT [FMA:68618] synonym: "Brodmann area 21" EXACT [] synonym: "BA21" EXACT ABBREVIATION [] synonym: "Area temporalis media" RELATED [NIF_GrossAnatomy:birnlex_1752] synonym: "B09-21" EXACT [NIF_GrossAnatomy:birnlex_1752] synonym: "Brodmann area 21, middle temporal" EXACT [NIF_GrossAnatomy:birnlex_1752] synonym: "area 21 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1752] synonym: "brodmann (1909) area 21" EXACT [NIF_GrossAnatomy:birnlex_1752] synonym: "Brodmann area 21" EXACT [] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area relationship: part_of UBERON:0004685 {notes="consider merging many sources treat as synonymous"} ! middle temporal area xref: FMA:68618 ! Brodmann area 21 xref: NIF_GrossAnatomy:birnlex_1752 ! Brodmann (1909) area 21 [Term] id: UBERON:0013553 name: Brodmann (1909) area 22 def: "Brodmann area 22 is one of Brodmann's cytologically defined regions of the brain. It is involved in auditory processing." [Wikipedia:Brodmann_area_22] synonym: "Area temporalis superior" EXACT LATIN [Wikipedia:Brodmann_area_22] synonym: "Area temporalis superior" EXACT [NIF_GrossAnatomy:birnlex_1753] synonym: "B09-22" EXACT [NIF_GrossAnatomy:birnlex_1753] synonym: "Brodmann area 22, superior temporal" EXACT [NIF_GrossAnatomy:birnlex_1753] synonym: "area 22 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1753] synonym: "brodmann (1909) area 22" EXACT [NIF_GrossAnatomy:birnlex_1753] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1753 ! Brodmann (1909) area 22 synonym: "Area 22 of Brodmann" EXACT [FMA:68619] synonym: "Superior temporal area" EXACT [FMA:68619] xref: FMA:68619 ! Brodmann area 22 synonym: "Brodmann area 22" EXACT [FMA:68619] [Term] id: UBERON:0013554 name: Brodmann (1909) area 23 def: "Brodmann area 23 (BA23) is a region in the brain corresponding to some portion of the posterior cingulate cortex. It lies between Brodmann area 30 and Brodmann area 31 and is located on the medial wall of the cingulate gyrus between the callosal sulcus and the cingulate sulcus." [Wikipedia:Brodmann_area_23] synonym: "Area cingularis posterior ventralis" EXACT LATIN [Wikipedia:Brodmann_area_23] synonym: "Area cingularis posterior ventralis" EXACT [NIF_GrossAnatomy:birnlex_1754] synonym: "B09-23" EXACT [NIF_GrossAnatomy:birnlex_1754] synonym: "Brodmann area 23, ventral posterior cingulate" EXACT [NIF_GrossAnatomy:birnlex_1754] synonym: "area 23 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1754] synonym: "brodmann (1909) area 23" EXACT [NIF_GrossAnatomy:birnlex_1754] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1754 ! Brodmann (1909) area 23 synonym: "Area 23 of Brodmann" EXACT [FMA:68620] synonym: "Granular cingulate area" EXACT [FMA:68620] synonym: "Posterior cingulate area" EXACT [FMA:68620] xref: FMA:68620 ! Brodmann area 23 synonym: "Brodmann area 23" EXACT [FMA:68620] [Term] id: UBERON:0013556 name: Brodmann (1909) area 25 synonym: "Area subgenualis" EXACT [NIF_GrossAnatomy:birnlex_1756] synonym: "B09-25" EXACT [NIF_GrossAnatomy:birnlex_1756] synonym: "Brodmann area 25, subgenual" EXACT [NIF_GrossAnatomy:birnlex_1756] synonym: "area 25 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1756] synonym: "brodmann (1909) area 25" EXACT [NIF_GrossAnatomy:birnlex_1756] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1756 ! Brodmann (1909) area 25 synonym: "Area 25 of Brodmann" EXACT [FMA:68622] synonym: "Brodmann's area 25" EXACT [FMA:68622] xref: FMA:68622 ! Brodmann area 25 synonym: "Brodmann area 25" EXACT [FMA:68622] [Term] id: UBERON:0001953 name: presubiculum def: "a modified six-layered cortex between the subiculum and the main part of the parahippocampal gyrus." [http://medical-dictionary.thefreedictionary.com/presubiculum] comment: Consider merging with BA27 synonym: "presubiculum (Cajal)" EXACT [NIF_GrossAnatomy:birnlex_1108] synonym: "area 27 of Brodmann" RELATED INCONSISTENT [FMA:62486] xref: FMA:62486 ! Presubiculum xref: MA:0000923 ! presubiculum xref: NIF_GrossAnatomy:birnlex_1108 ! Presubiculum xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5f/Brodmann_Cytoarchitectonics_27.png/200px-Brodmann_Cytoarchitectonics_27.png xref: ABA:PRE ! Presubiculum xref: BM:Tel-Cx-PSB ! presubiculum is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002973 {source="FMA"} ! parahippocampal gyrus relationship: spatially_disjoint_from UBERON:0002728 {source="ABA"} ! entorhinal area relationship: spatially_disjoint_from UBERON:0004683 {source="ABA"} ! parasubiculum relationship: spatially_disjoint_from UBERON:0002191 {source="ABA"} ! subiculum xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Brodmann_Cytoarchitectonics_27.png [Term] id: UBERON:0013558 name: Brodmann (1909) area 27 def: "Area 27 of Brodmann-1909 is a cytoarchitecturally defined cortical area that is a rostral part of the parahippocampal gyrus of the guenon (Brodmann-1909). It is commonly regarded as a synonym of presubiculum (Crosby-62). [WP,unvetted]." [Wikipedia:Brodmann_area_27] synonym: "area 27 of Brodmann" EXACT [] synonym: "Brodmann area 27" EXACT [] synonym: "BA27" EXACT ABBREVIATION [] synonym: "Area praesubicularis" EXACT [NIF_GrossAnatomy:birnlex_1758] synonym: "B09-27" EXACT [NIF_GrossAnatomy:birnlex_1758] synonym: "Brodmann area 26, presubicular" EXACT [NIF_GrossAnatomy:birnlex_1758] synonym: "area 27 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1758] synonym: "brodmann (1909) area 27" EXACT [NIF_GrossAnatomy:birnlex_1758] synonym: "Area 27" EXACT [FMA:68624] synonym: "Presubicular area" EXACT [FMA:68624] synonym: "Brodmann area 27" EXACT [FMA:68624] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area relationship: part_of UBERON:0001953 {notes="consider merging many sources treat as synonymous"} ! presubiculum xref: NIF_GrossAnatomy:birnlex_1758 ! Brodmann (1909) area 27 xref: FMA:68624 ! Brodmann area 27 [Term] id: UBERON:0002895 name: secondary olfactory cortex def: "Brodmann's area 28; major gateway for neocortical input to the hippocampus; origin of the perforant pathway; a component of the medial temporal lobe memory system. (CSP) * The cytoarchitecturally well-defined area of multilaminate cerebral cortex on the medial aspect of the parahippocampal gyrus, immediately caudal to the olfactory cortex of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the hippocampus, the so-called PERFORANT PATHWAY. (Stedman, 25th ed)." [NIF_GrossAnatomy:birnlex_2709] comment: FMA considers this a syn of entorhinal cortex. See also brodman definition subset: uberon_slim synonym: "entorhinal cortex" RELATED INCONSISTENT [FMA:72356] synonym: "secondary olfactory cortex" EXACT [FMA:72356] synonym: "secondary olfactory cortical area (carpenter)" EXACT [] synonym: "secondary olfactory areas" EXACT [NIF_GrossAnatomy:birnlex_2709] xref: NIF_GrossAnatomy:birnlex_2709 ! Secondary olfactory cortex xref: BTO:0004345 ! entorhinal cortex xref: EV:0100179 ! secondary olfactory cortex is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0000956 {source="FMA"} ! cerebral cortex relationship: part_of UBERON:0002894 {source="NIF"} ! olfactory cortex [Term] id: UBERON:0013559 name: Brodmann (1909) area 28 def: "." [Wikipedia:Brodmann_area_28] synonym: "Area entorhinalis ventralis" EXACT LATIN [Wikipedia:Brodmann_area_28] xref: http://upload.wikimedia.org/wikipedia/commons/7/76/Brodmann_Cytoarchitectonics_28.png synonym: "area 28 of Brodmann (crosby)" EXACT [] synonym: "area 28 of Brodmann" EXACT [] synonym: "Brodmann area 28" EXACT [FMA:68625] synonym: "BA28" EXACT ABBREVIATION [] synonym: "Area entorhinalis" EXACT [NIF_GrossAnatomy:birnlex_1759] synonym: "B09-28" EXACT [NIF_GrossAnatomy:birnlex_1759] synonym: "Brodmann area 28, entorhinal" EXACT [NIF_GrossAnatomy:birnlex_1759] synonym: "area 28 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1759] synonym: "brodmann (1909) area 28" EXACT [NIF_GrossAnatomy:birnlex_1759] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area relationship: part_of UBERON:0002895 {notes="consider merging many sources treat as synonymous"} ! secondary olfactory cortex xref: NIF_GrossAnatomy:birnlex_1759 ! Brodmann (1909) area 28 xref: FMA:68625 ! Brodmann area 28 synonym: "Brodmann area 28" EXACT [] [Term] id: UBERON:0013560 name: Brodmann (1909) area 32 def: "The Brodmann area 32, also known in the human brain as the dorsal anterior cingulate area 32, refers to a subdivision of the cytoarchitecturally defined cingulate region of cerebral cortex. In the human it forms an outer arc around the anterior cingulate gyrus. The cingulate sulcus defines approximately its inner boundary and the superior rostral sulcus (H) its ventral boundary; rostrally it extends almost to the margin of the frontal lobe. Cytoarchitecturally it is bounded internally by the ventral anterior cingulate area 24, externally by medial margins of the agranular frontal area 6, intermediate frontal area 8, granular frontal area 9, frontopolar area 10, and prefrontal area 11-1909. (Brodmann19-09). Dorsal region of anterior cingulate gyrus is associated with rational thought processes, most notably active during the Stroop task." [Wikipedia:Brodmann_area_32] synonym: "Area cingularis anterior dorsalis" EXACT LATIN [Wikipedia:Brodmann_area_32] synonym: "Area cingularis anterior dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1760] synonym: "B09-32" EXACT [NIF_GrossAnatomy:birnlex_1760] synonym: "Brodmann area 32, dorsal anterior cingulate" EXACT [NIF_GrossAnatomy:birnlex_1760] synonym: "area 32 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1760] synonym: "brodmann (1909) area 32" EXACT [NIF_GrossAnatomy:birnlex_1760] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1760 ! Brodmann (1909) area 32 synonym: "Area 32 of Brodmann" EXACT [FMA:68629] synonym: "Prelimbic area" EXACT [FMA:68629] xref: FMA:68629 ! Brodmann area 32 synonym: "Brodmann area 32" EXACT [FMA:68629] [Term] id: UBERON:0013561 name: Brodmann (1909) area 43 synonym: "Area subcentralis" EXACT [NIF_GrossAnatomy:birnlex_1761] synonym: "B09-43" EXACT [NIF_GrossAnatomy:birnlex_1761] synonym: "Brodmann area 43, subcentral" EXACT [NIF_GrossAnatomy:birnlex_1761] synonym: "area 43 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1761] synonym: "brodmann (1909) area 43" EXACT [NIF_GrossAnatomy:birnlex_1761] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1761 ! Brodmann (1909) area 43 synonym: "Brodmann area 43" EXACT [] [Term] id: UBERON:0013562 name: Brodmann (1909) area 8a synonym: "B09-8a" EXACT [NIF_GrossAnatomy:birnlex_1762] synonym: "area 8a of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1762] synonym: "brodmann (1909) area 8a" EXACT [NIF_GrossAnatomy:birnlex_1762] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area xref: NIF_GrossAnatomy:birnlex_1762 ! Brodmann (1909) area 8a synonym: "Brodmann area 8a" EXACT [] [Term] id: UBERON:0002688 name: supramarginal gyrus subset: uberon_slim synonym: "anterior part of inferior parietal lobule" EXACT [FMA:61897] synonym: "inferior parietal lobule (krieg)" EXACT [] synonym: "Brodmann area 40" RELATED [Wikipedia:Supramarginal_gyrus] synonym: "BA40" RELATED ABBREVIATION [] xref: FMA:61897 ! Supramarginal gyrus xref: NIF_GrossAnatomy:birnlex_1381 ! Supramarginal gyrus xref: ncithesaurus:Supramarginal_Gyrus ! Supramarginal Gyrus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Gehirn%2C_lateral_-_Hauptgyri_beschriftet.svg/200px-Gehirn%2C_lateral_-_Hauptgyri_beschriftet.svg.png is_a: UBERON:0000200 ! gyrus relationship: part_of UBERON:0001872 ! parietal lobe xref: SCTID:279185008 ! Entire supramarginal gyrus xref: http://upload.wikimedia.org/wikipedia/commons/e/ec/Gehirn,_lateral_-_Hauptgyri_beschriftet.svg xref: UMLS:C0228214 [Term] id: UBERON:0013573 name: Brodmann (1909) area 40 def: "Brodmann area 40, or BA40, is part of the parietal cortex in the human brain. The inferior part of BA40 is in the area of the supramarginal gyrus, which lies at the posterior end of the lateral fissure, in the inferior lateral part of the parietal lobe. It is bounded approximately by the intraparietal sulcus, the inferior postcentral sulcus, the posterior subcentral sulcus and the lateral sulcus. Cytoarchitecturally it is bounded caudally by the angular area 39 (H), rostrally and dorsally by the caudal postcentral area 2, and ventrally by the subcentral area 43 and the superior temporal area 22 (Brodmann-1909). Cytoarchitectonically defined subregions of rostral BA40/the supramarginal gyrus are PF, PFcm, PFm, PFop, and PFt. Area PF is the homologue to macaque area PF, part of the mirror neuron system, and active in humans during imitation. The supramarginal gyrus part of Brodmann area 40 is the region in the inferior parietal lobe that is involved in reading both in regards to meaning and phonology. [WP,unvetted]." [Wikipedia:Supramarginal_gyrus] synonym: "Area supramarginalis" EXACT [NIF_GrossAnatomy:birnlex_1773] synonym: "B09-40" EXACT [NIF_GrossAnatomy:birnlex_1773] synonym: "Brodmann area 40, supramarginal" EXACT [NIF_GrossAnatomy:birnlex_1773] synonym: "area 40 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1773] synonym: "brodmann (1909) area 40" EXACT [NIF_GrossAnatomy:birnlex_1773] is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area relationship: part_of UBERON:0002688 {notes="consider merging many sources treat as synonymous"} ! supramarginal gyrus xref: NIF_GrossAnatomy:birnlex_1773 ! Brodmann (1909) area 40 synonym: "Area 40 of Brodmann" EXACT [FMA:68637] synonym: "Supramarginal area 40" EXACT [FMA:68637] xref: FMA:68637 ! Brodmann area 40 synonym: "Brodmann area 40" EXACT [FMA:68637] [Term] id: UBERON:0006095 alt_id: UBERON:0013574 name: anterior transverse termporal area 41 synonym: "Brodmann's area 41" EXACT [NIF_GrossAnatomy:birnlex_1582] synonym: "anterior transverse termporal area 41" EXACT [NIF_GrossAnatomy:birnlex_1582] synonym: "area 41 of Brodmann" EXACT [NIF_GrossAnatomy:birnlex_1582] synonym: "principle auditory receptive areas" EXACT [NIF_GrossAnatomy:birnlex_1582] synonym: "anterior transverse temporal area 41" EXACT [FMA:68638] synonym: "area 41 of Brodmann" EXACT [FMA:68638] synonym: "Brodmann area 41" EXACT [FMA:68638] synonym: "BA41" EXACT ABBREVIATION [] synonym: "Area temporalis transversa anterior" EXACT [NIF_GrossAnatomy:birnlex_1774] synonym: "B09-41" EXACT [NIF_GrossAnatomy:birnlex_1774] synonym: "Brodmann area 41, anterior transverse temporal" EXACT [NIF_GrossAnatomy:birnlex_1774] synonym: "area 41 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1774] synonym: "brodmann (1909) area 41" EXACT [NIF_GrossAnatomy:birnlex_1774] synonym: "Brodmann area 41" EXACT [] xref: NIF_GrossAnatomy:birnlex_1774 ! Brodmann (1909) area 41 xref: FMA:68638 ! Brodmann area 41 xref: NIF_GrossAnatomy:birnlex_1582 ! Anterior transverse termporal area 41 is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area [Term] id: UBERON:0006096 alt_id: UBERON:0013575 name: posterior transverse termporal area 42 synonym: "Brodmann's area 42" EXACT [NIF_GrossAnatomy:birnlex_1589] synonym: "area 42 of Brodmann" EXACT [NIF_GrossAnatomy:birnlex_1589] synonym: "auditory association area" EXACT [NIF_GrossAnatomy:birnlex_1589] synonym: "posterior transverse termporal area 42" EXACT [NIF_GrossAnatomy:birnlex_1589] synonym: "area 42 of Brodmann" EXACT [FMA:68639] synonym: "posterior transverse temporal area 42" EXACT [FMA:68639] synonym: "Brodmann area 42" EXACT [FMA:68639] synonym: "BA42" EXACT ABBREVIATION [] synonym: "Brodmann area 42" EXACT [] synonym: "Area temporalis transversa posterior" EXACT [NIF_GrossAnatomy:birnlex_1775] synonym: "B09-42" EXACT [NIF_GrossAnatomy:birnlex_1775] synonym: "Brodmann area 42, posterior transverse temporal" EXACT [NIF_GrossAnatomy:birnlex_1775] synonym: "area 42 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1775] synonym: "brodmann (1909) area 42" EXACT [NIF_GrossAnatomy:birnlex_1775] xref: FMA:68639 ! Brodmann area 42 xref: NIF_GrossAnatomy:birnlex_1589 ! Posterior transverse termporal area 42 xref: NIF_GrossAnatomy:birnlex_1775 ! Brodmann (1909) area 42 is_a: UBERON:0013529 {source="NIF_GrossAnatomy"} ! Brodmann area [Term] id: UBERON:0013531 name: retrosplenial region def: "The retrosplenial region is a brain area and part of the cingulate cortex. It is defined by Brodmann area 26, Brodmann area 29 and the Brodmann area 30." [Wikipedia:Retrosplenial_region] synonym: "retrosplenial cortex" RELATED [Wikipedia:Retrosplenial_region] synonym: "retrosplenial cortex" RELATED [BTO:0003977] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0003027 {source="BTO"} ! cingulate cortex xref: BTO:0003977 ! retrosplenial region property_value: external_definition "The retrosplenial region is a brain area and part of the cingulate cortex. It is defined by Brodmann area 29 and the Brodmann area 26[BTO:0003977]." xsd:string {source="BTO:0003977"} [Term] id: UBERON:0006105 name: obsolete basis modioli consider: FMA:75640 ! base of modiolus of cochlea consider: NIF_GrossAnatomy:birnlex_2522 ! Basis modioli is_obsolete: true synonym: "basis modioli cochleae" EXACT LATIN [FMA:TA, FMA:75640] [Term] id: UBERON:0006106 name: cochlear canal synonym: "spiral canal of cochlea" EXACT [NIF_GrossAnatomy:birnlex_2553] synonym: "cochlear canal" EXACT [NIF_GrossAnatomy:birnlex_2553] synonym: "wall of cochlea" EXACT [FMA:75371] xref: FMA:75371 ! spiral canal of cochlea xref: NIF_GrossAnatomy:birnlex_2553 ! Cochlear canal is_a: UBERON:0002558 ! organ cavity relationship: part_of UBERON:0001844 ! cochlea xref: SCTID:279779009 ! Entire cochlear canal [Term] id: UBERON:0006108 name: corticomedial nuclear complex synonym: "CMA" EXACT [NIF_GrossAnatomy:birnlex_2680] synonym: "amygdalar corticomedial nucleus" EXACT [NIF_GrossAnatomy:birnlex_2680] synonym: "corticomedial nuclear complex" EXACT [NIF_GrossAnatomy:birnlex_2680] synonym: "corticomedial nuclear group" EXACT [NIF_GrossAnatomy:birnlex_2680] synonym: "pars corticomedialis (Corpus amygdaloideum)" EXACT [NIF_GrossAnatomy:birnlex_2680] synonym: "corticomedial nuclear group" EXACT [FMA:84015] synonym: "corticomedial nuclei of amygdala" EXACT [FMA:84015] xref: FMA:84015 ! set of corticomedial nuclei of amygdala xref: NIF_GrossAnatomy:birnlex_2680 ! Corticomedial nuclear complex is_a: UBERON:0007245 ! nuclear complex of neuraxis relationship: part_of BERON:0001876 ! amygdala synonym: "set of corticomedial nuclei of amygdala" EXACT [FMA:84015] [Term] id: UBERON:0006114 name: lateral occipital cortex def: "Component of the occipital lobe. The rostral and caudal boundaries of the lateral occipital cortex were the superior parietal gyrus and as the last visible portion of occipital cortex respectively. The medial and lateral boundaries were the cuneus/pericalcarine cortex and the inferior temporal/inferior parietal gyri respectively (Christine Fennema-Notestine)." [NIF_GrossAnatomy:birnlex_735] synonym: "lateral occipital cortex" EXACT [NIF_GrossAnatomy:birnlex_735] synonym: "lateral occipital gyrus" EXACT [NIF_GrossAnatomy:birnlex_735] synonym: "gyrus occipitalis medius (mai)" EXACT [FMA:61902] synonym: "gyrus occipitalis secundus" EXACT [FMA:61902] xref: FMA:61902 ! lateral occipital gyrus xref: NIF_GrossAnatomy:birnlex_735 ! Lateral occipital cortex is_a: UBERON:0003022 ! lobe parts of cerebral cortex relationship: part_of UBERON:0001950 ! neocortex relationship: part_of UBERON:0002021 ! occipital lobe xref: SCTID:369218006 ! Entire lateral occipital gyrus [Term] id: UBERON:0006115 name: posterior column of fornix synonym: "crus of fornix" EXACT [NIF_GrossAnatomy:birnlex_754] synonym: "posterior column of fornix" EXACT [NIF_GrossAnatomy:birnlex_754] synonym: "posterior crus of fornix" EXACT [NIF_GrossAnatomy:birnlex_754] synonym: "posterior pillar of fornix" EXACT [NIF_GrossAnatomy:birnlex_754] synonym: "crus of fornix" EXACT [FMA:61969] synonym: "posterior crus of fornix" EXACT [FMA:61969] synonym: "posterior pillar of fornix" EXACT [FMA:61969] synonym: "posterior column of fornix of forebrain" EXACT [FMA:61969] xref: FMA:61969 ! posterior column of fornix of forebrain xref: NIF_GrossAnatomy:birnlex_754 ! Posterior column of fornix is_a: UBERON:0000122 ! nerve fiber bundle is_a: UBERON:0002780 ! regional part of forebrain synonym: "crus fornicis" EXACT LATIN [FMA:TA, FMA:61969] xref: SCTID:369116002 ! Entire crus of fornix [Term] id: UBERON:0006116 name: vagal nerve fiber bundle synonym: "central part of vagus nerve" EXACT [NIF_GrossAnatomy:birnlex_765] synonym: "tenth cranial nerve fibers" EXACT [NIF_GrossAnatomy:birnlex_765] synonym: "vagal nerve fiber bundle" EXACT [NIF_GrossAnatomy:birnlex_765] synonym: "vagal nerve fibers" EXACT [NIF_GrossAnatomy:birnlex_765] synonym: "central part of vagus nerve" EXACT [FMA:72628] synonym: "tenth cranial nerve fibers" EXACT [FMA:72628] synonym: "vagal nerve fibers" EXACT [FMA:72628] synonym: "vagal nerve tract" EXACT [FMA:72628] xref: FMA:72628 ! vagal nerve tract xref: NIF_GrossAnatomy:birnlex_765 ! Vagal nerve fiber bundle is_a: UBERON:0000122 ! nerve fiber bundle relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0006117 name: accessory nerve fiber bundle synonym: "accessory nerve fiber bundle" EXACT [NIF_GrossAnatomy:birnlex_916] synonym: "accessory nerve fibers" EXACT [NIF_GrossAnatomy:birnlex_916] synonym: "accessory nerve fibers" EXACT [FMA:72626] synonym: "eleventh cranial nerve fibers" EXACT [FMA:72626] synonym: "accessory nerve tract" EXACT [FMA:72626] xref: FMA:72626 ! accessory nerve tract xref: NIF_GrossAnatomy:birnlex_916 ! Accessory nerve fiber bundle is_a: UBERON:0000122 ! nerve fiber bundle relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0006118 name: lamina I of gray matter of spinal cord synonym: "lamina marginalis" EXACT [NIF_GrossAnatomy:nlx_anat_100203] synonym: "layer of Waldeyer" EXACT [NIF_GrossAnatomy:nlx_anat_100203] synonym: "rexed lamina I" EXACT [NIF_GrossAnatomy:nlx_anat_100203] synonym: "rexed layer 1" EXACT [NIF_GrossAnatomy:nlx_anat_100203] synonym: "spinal lamina I" EXACT [NIF_GrossAnatomy:nlx_anat_100203] synonym: "lamina i of gray matter of spinal cord" EXACT [NIF_GrossAnatomy:nlx_anat_100203] synonym: "lamina marginalis" EXACT [FMA:68862] synonym: "layer of waldeyer" EXACT [FMA:68862] synonym: "rexed lamina i" EXACT [FMA:68862] synonym: "spinal lamina i" EXACT [FMA:68862] xref: FMA:68862 ! lamina i of gray matter of spinal cord xref: NIF_GrossAnatomy:nlx_anat_100203 ! Lamina I of gray matter of spinal cord is_a: UBERON:0001948 ! regional part of spinal cord relationship: part_of UBERON:0002256 ! dorsal horn of spinal cord synonym: "lamina spinalis i" EXACT LATIN [FMA:TA, FMA:68862] [Term] id: UBERON:0011214 name: nucleus of midbrain tectum synonym: "nucleus of tectum" EXACT [FMA:258766] synonym: "tectal nucleus" BROAD [] intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0002314 ! midbrain tectum xref: FMA:258766 ! nucleus of tectum def: "A neural nucleus that is part of a midbrain tectum." [OBOL:automatic] [Term] id: UBERON:0006119 name: subbrachial nucleus comment: Candidate definition (refers specifically to mouse): "A group of cells ventral to the nucleus of brachium of inferior colliculus in the mouse (Paxinos-2001)." [NIF_GrossAnatomy:nlx_anat_1005003] synonym: "subbrachial nucleus" EXACT [NIF_GrossAnatomy:nlx_anat_1005003] synonym: "tegmental area of tsai" EXACT [FMA:77494] xref: FMA:77494 ! subbrachial nucleus xref: NIF_GrossAnatomy:nlx_anat_1005003 ! Subbrachial nucleus is_a: UBERON:0011214 {source="FMA"} ! nucleus of midbrain tectum [Term] id: UBERON:0006121 name: hemispheric lobule VIII synonym: "Biventer 1 (HVIII)" EXACT [NIF_GrossAnatomy:nlx_anat_20081211] synonym: "Biventral Lobule" EXACT [NIF_GrossAnatomy:nlx_anat_20081211] synonym: "Lobulus Biventer" EXACT [NIF_GrossAnatomy:nlx_anat_20081211] synonym: "Paraflocculus Dorsalis" EXACT [NIF_GrossAnatomy:nlx_anat_20081211] synonym: "hemispheric lobule viii" EXACT [NIF_GrossAnatomy:nlx_anat_20081211] synonym: "biventral lobule" EXACT [FMA:72526] synonym: "biventral lobule [h viii]" EXACT [FMA:72526] synonym: "cuneiform lobe" EXACT [FMA:72526] synonym: "dorsal parafloccularis [h viii b]" EXACT [FMA:72526] synonym: "dorsal paraflocculus" EXACT [FMA:72526] synonym: "biventer lobule" EXACT [FMA:72526] xref: FMA:72526 ! biventer lobule xref: NIF_GrossAnatomy:nlx_anat_20081211 ! Hemispheric Lobule VIII is_a: UBERON:0004003 ! cerebellum hemisphere lobule synonym: "lobulus parafloccularis dorsalis [h viii b]" EXACT LATIN [FMA:TA, FMA:72526] synonym: "lobulus biventer [h viii]" EXACT LATIN [FMA:TA, FMA:72526] [Term] id: UBERON:0006123 name: horizontal limb of the diagonal band synonym: "Diagonal band horizontal limb" EXACT [NIF_GrossAnatomy:nlx_anat_20090303] synonym: "Horizontal limb of the diagonal band of Broca" EXACT [NIF_GrossAnatomy:nlx_anat_20090303] synonym: "hDBB" EXACT [NIF_GrossAnatomy:nlx_anat_20090303] synonym: "horizontal limb of the diagonal band" EXACT [NIF_GrossAnatomy:nlx_anat_20090303] synonym: "horizontal limb of diagonal band" EXACT [FMA:77611] xref: FMA:77611 ! horizontal limb of diagonal band xref: NIF_GrossAnatomy:nlx_anat_20090303 ! Horizontal limb of the diagonal band is_a: UBERON:0006125 ! subdivision of diagonal band [Term] id: UBERON:0006124 name: vertical limb of the diagonal band synonym: "Vertical limb of the diagonal band of Broca" EXACT [NIF_GrossAnatomy:nlx_anat_20090304] synonym: "vertical limb of the diagonal band" EXACT [NIF_GrossAnatomy:nlx_anat_20090304] synonym: "vertical limb of diagonal band" EXACT [FMA:77612] xref: FMA:77612 ! vertical limb of diagonal band xref: NIF_GrossAnatomy:nlx_anat_20090304 ! Vertical limb of the diagonal band is_a: UBERON:0006125 ! subdivision of diagonal band [Term] id: UBERON:0006125 ! subdivision of diagonal band name: subdivision of diagonal band synonym: "diagonal band subdivision" EXACT [FMA:77610] synonym: "regional part of diagonal band" EXACT [NIF_GrossAnatomy:nlx_anat_20090302] xref: FMA:77610 ! subdivision of diagonal band xref: NIF_GrossAnatomy:nlx_anat_20090302 ! Regional part of diagonal band is_a: UBERON:0002791 ! regional part of telencephalon subset: non_informative [Term] id: UBERON:0006171 ! renal sinus name: renal sinus xref: FMA:15611 ! renal sinus is_a: UBERON:0002558 ! organ cavity relationship: part_of UBERON:0002113 ! kidney xref: SCTID:362222000 ! Entire renal sinus [Term] id: UBERON:0006172 name: rectal diverticulum def: "The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior" [GO:0039009] xref: XAO:0001015 ! rectal diverticulum is_a: UBERON:0000061 ! anatomical structure relationship: continuous_with UBERON:0002120 ! pronephros relationship: continuous_with UBERON:0000163 ! embryonic cloaca [Term] id: UBERON:0006174 name: pronephric sinus def: "The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules" [GO:0039012] comment: todo - check relationship to renal sinus, improve definition xref: XAO:0000385 ! pronephric sinus intersection_of: UBERON:0006171 ! renal sinus intersection_of: part_of UBERON:0002120 ! pronephros xref: AAO:0011092 ! pronephric sinus [Term] id: UBERON:0006196 name: mesonephric sinus comment: todo - check relationship to renal sinus, add definition xref: XAO:0000381 ! mesonephric sinus intersection_of: UBERON:0006171 ! renal sinus intersection_of: part_of UBERON:0000080 ! mesonephros xref: AAO:0011063 ! mesonephric sinus def: "A renal sinus that is part of a mesonephros." [OBOL:automatic] [Term] id: UBERON:0006175 name: pronephric distal tubule def: "A pronephric nephron tubule is an epithelial tube that is part of the pronephros" [GO:0039013] intersection_of: UBERON:0004135 ! distal tubule intersection_of: part_of UBERON:0002120 ! pronephros is_a: UBERON:0005310 ! pronephric nephron tubule relationship: part_of UBERON:0005309 {source="reference_0000032"} ! pronephric nephron [Term] id: UBERON:0006182 name: mesonephric glomerular mesangium def: "The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus" [GO:0061247] intersection_of: UBERON:0002320 ! glomerular mesangium intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005326 {is_inferred="true", source="reference_0000032"} ! mesonephric glomerulus vasculature [Term] id: UBERON:0006183 name: mesonephric glomerular capillary def: "." [GO:0061249] intersection_of: UBERON:0004212 ! glomerular capillary intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005325 {is_inferred="true", source="reference_0000032"} ! mesonephric glomerulus relationship: part_of UBERON:0005322 {source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0006189 name: mesonephric connecting tubule def: "The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros" [GO:0061272] intersection_of: UBERON:0005097 ! connecting tubule intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005322 {source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0006190 name: mesonephric distal tubule def: "The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule" [GO:0061273] comment: note that ZFA has terms for developing tubule intersection_of: UBERON:0004135 ! distal tubule intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005322 {source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0006192 name: mesonephric proximal tubule def: "The mesonephric proximal tubule extends from the capsule to the distal tubule" [GO:0061275] comment: note that ZFA has terms for developing tubule intersection_of: UBERON:0004134 ! proximal tubule intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005322 {source="reference_0000032"} ! mesonephric nephron [Term] id: UBERON:0006194 name: renal sinus of right kidney synonym: "right renal sinus" EXACT [FMA:17621] xref: FMA:17621 ! renal sinus of right kidney intersection_of: UBERON:0006171 ! renal sinus intersection_of: part_of UBERON:0004539 ! right kidney def: "A renal sinus that is part of a right kidney." [OBOL:automatic] [Term] id: UBERON:0006195 name: renal sinus of left kidney synonym: "left renal sinus" EXACT [FMA:17622] xref: FMA:17622 ! renal sinus of left kidney intersection_of: UBERON:0006171 ! renal sinus intersection_of: part_of UBERON:0004538 ! left kidney def: "A renal sinus that is part of a left kidney." [OBOL:automatic] [Term] id: UBERON:0006198 name: dorsal intercostal artery def: "The highest intercostal artery (supreme intercostal artery, superior intercostal artery) is an artery in the human body that usually gives rise to the first and second posterior intercostal arteries, which supply blood to their corresponding intercostal space. It usually arises from the costocervical trunk, which is a branch of the subclavian artery." [Wikipedia:Highest_intercostal_artery] comment: classes unified on basis of spatial anatomy ontology synonyms synonym: "superior intercostal artery" EXACT [FMA:76998, Wikipedia:Highest_intercostal_artery] synonym: "supreme intercostal artery" EXACT [FMA:76998, Wikipedia:Highest_intercostal_artery] synonym: "dorsal branch of superior intercostal artery" RELATED [http://www.mondofacto.com/facts/dictionary?dorsal+branch+of+the+superior+intercostal+artery] xref: FMA:76998 ! Supreme intercostal artery xref: MA:0001943 ! dorsal intercostal artery is_a: UBERON:0005612 ! intercostal artery xref: SCTID:198427009 ! Entire superior intercostal artery synonym: "arteria intercostalis suprema" RELATED LATIN [Wikipedia:Highest_intercostal_artery] xref: http://upload.wikimedia.org/wikipedia/commons/7/75/Gray530.png [Term] id: UBERON:0006200 name: caudal humeral circumflex vein comment: classes unified on basis of spatial anatomy ontology synonyms synonym: "posterior circumflex humeral vein" EXACT [FMA:71216] synonym: "posterior humeral circumflex vein" EXACT [FMA:71216] xref: FMA:71216 ! Posterior humeral circumflex vein xref: MA:0002091 ! caudal humeral circumflex vein is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001587 {source="FMA/obol"} ! subclavian vein relationship: tributary_of UBERON:0000985 {source="FMA/obol"} ! axillary vein synonym: "vena circumflexa humeri posterior" EXACT LATIN [FMA:TA, FMA:71216] [Term] id: UBERON:0006201 name: dorsal cerebral vein comment: classes unified on basis of spatial anatomy ontology synonyms synonym: "superior cerebral vein" EXACT [FMA:50978] xref: FMA:50978 ! Superior cerebral vein xref: MA:0002103 ! dorsal cerebral vein is_a: UBERON:0001663 ! cerebral vein xref: SCTID:244393005 ! Entire superior cerebral vein [Term] id: UBERON:0006208 name: auditory hillocks subset: emapa_ehdaa2 xref: EMAPA:17280 ! auditory hillocks xref: EHDAA2:0000155 ! auditory hillocks xref: VHOG:0001364 ! auditory hillocks xref: EHDAA:4685 ! auditory hillocks is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0001691 ! external ear synonym: "auditory tubercles" RELATED INCONSISTENT [VHOG:0001364] synonym: "auricular hillock" RELATED [] property_value: homology_notes "Mammals have a third type of tympanic ear. An external flap, the auricle or pinna, helps funnel sound waves down the external acoustic meatus to the tympanic membrane.[inferred][VHOG]" xsd:string {external_class="VHOG:0001364", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.420", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006209 ! basioccipital cartilage condensation name: basioccipital cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:18337 ! basioccipital cartilage condensation xref: EHDAA2:0000164 ! basioccipital cartilage condensation xref: VHOG:0001124 ! basioccipital cartilage condensation xref: EHDAA:7141 ! basioccipital cartilage condensation is_a: UBERON:0005863 ! cartilagenous condensation relationship: develops_into UBERON:0001692 ! basioccipital bone relationship: develops_from UBERON:0009197 {source="EHDAA2"} ! basioccipital pre-cartilage condensation [Term] id: UBERON:0006210 name: body-wall mesenchyme subset: emapa_ehdaa2 xref: EMAPA:16893 ! body-wall mesenchyme xref: EHDAA2:0000179 ! body-wall mesenchyme xref: EHDAA:3217 ! body-wall mesenchyme is_a: UBERON:0003104 ! mesenchyme [Term] id: UBERON:0006211 name: buccopharyngeal membrane def: "The region where the crescentic masses of the ectoderm and endoderm come into direct contact with each other constitutes a thin membrane, the buccopharyngeal membrane (or oropharyngeal membrane), which forms a septum between the primitive mouth and pharynx. In front of the buccopharyngeal area, where the lateral crescents of mesoderm fuse in the middle line, the pericardium is afterward developed, and this region is therefore designated the pericardial area." [Wikipedia:Buccopharyngeal_membrane] subset: emapa_ehdaa2 synonym: "oropharyngeal membrane" RELATED [Wikipedia:Buccopharyngeal_membrane] xref: EMAPA:16259 ! buccopharyngeal membrane xref: EHDAA2:0000189 ! buccopharyngeal membrane xref: VHOG:0000380 ! buccopharyngeal membrane xref: EHDAA:536 ! buccopharyngeal membrane is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0003037 ! septum relationship: part_of UBERON:0006264 {source="EHDAA2"} ! mouth-foregut junction relationship: has_part UBERON:0000924 ! ectoderm relationship: has_part UBERON:0000925 ! endoderm relationship: overlaps UBERON:0000930 ! stomodeum relationship: overlaps UBERON:0001042 ! chordate pharynx xref: SCTID:361412007 ! Buccopharyngeal membrane xref: http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png [Term] id: UBERON:0009210 ! pharyngeal membrane name: pharyngeal membrane def: "a thin fold of ectoderm and endoderm that separates the pharyngeal pouches from the branchial clefts in a developing embryo." [http://musom.marshall.edu/anatomy/grosshom/z_devbranc.html] synonym: "pharyngeal membrane" EXACT [] xref: ncithesaurus:Pharyngeal_Membrane ! Pharyngeal Membrane is_a: UBERON:0002050 ! embryonic structure relationship: overlaps UBERON:0005879 ! pharyngeal cleft relationship: overlaps UBERON:0004117 ! pharyngeal pouch relationship: has_part UBERON:0000924 ! ectoderm relationship: has_part UBERON:0000925 ! endoderm xref: UMLS:C1519040 [Term] id: UBERON:0009213 ! 1st pharyngeal membrane name: pharyngeal membrane of 1st arch def: "separates the first pharyngeal groove from the first pharyngeal pouch." [ISBN10:1416037055] synonym: "future tympanic membrane" EXACT [EMAPA:17281] synonym: "tympanic membrane primordium" EXACT [ISBN10:1416037055] synonym: "1st branchial membrane" EXACT [EMAPA:16992] comment: check EMAPA - 3 terms appear to match. We follow EMAPA in making each membrane part of the arch with the same number, though in fact it is between these arches is_a: UBERON:0009210 ! pharyngeal membrane relationship: part_of UBERON:0004362 {source="EMAPA"} ! pharyngeal arch 1 relationship: overlaps UBERON:0005872 ! 1st arch pharyngeal cleft relationship: overlaps UBERON:0007122 ! pharyngeal pouch 1 xref: EMAPA:17281 ! future tympanic membrane xref: EMAPA:16992 ! 1st branchial membrane xref: EHDAA:3788 ! 1st branchial membrane xref: EMAPA:16121 ! branchial membrane of 1st arch xref: VHOG:0001427 ! 1st pharyngeal membrane synonym: "1st pharyngeal membrane" EXACT [VHOG:0001427] property_value: homology_notes "In all vertebrates, the endodermal epithelium lining each pouch contacts the surface ectoderm of the clefts to form a series of bilayered branchial membranes, that break down in fish to form the gill openings.[well established][VHOG]" xsd:string {external_class="VHOG:0001427", ontology="VHOG", source="ISBN:978-0124020603 Kaufman MH\, Bard JBL\, The anatomical basis of mouse development (1999) p.72", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009215 name: pharyngeal membrane of 2nd arch is_a: UBERON:0009210 ! pharyngeal membrane relationship: overlaps UBERON:0005873 ! 2nd arch pharyngeal cleft relationship: overlaps UBERON:0007123 ! pharyngeal pouch 2 relationship: part_of UBERON:0003066 {source="EMAPA"} ! pharyngeal arch 2 xref: EMAPA:16273 ! branchial membrane of 2nd arch xref: VHOG:0000877 ! 2nd pharyngeal membrane synonym: "2nd pharyngeal membrane" EXACT [VHOG:0000877] property_value: homology_notes "In all vertebrates, the endodermal epithelium lining each pouch contacts the surface ectoderm of the clefts to form a series of bilayered branchial membranes, that break down in fish to form the gill openings.[well established][VHOG]" xsd:string {external_class="VHOG:0000877", ontology="VHOG", source="ISBN:978-0124020603 Kaufman MH and Bard JBL\, The anatomical basis of mouse development (1999) p.72", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009216 name: pharyngeal membrane of 3rd arch is_a: UBERON:0009210 ! pharyngeal membrane relationship: overlaps UBERON:0005874 ! 3rd arch pharyngeal cleft relationship: overlaps UBERON:0007124 ! pharyngeal pouch 3 relationship: part_of UBERON:0003114 {source="EMAPA"} ! pharyngeal arch 3 xref: EMAPA:16583 ! branchial membrane of 3rd arch xref: VHOG:0000876 ! 3rd pharyngeal membrane synonym: "3rd pharyngeal membrane" EXACT [VHOG:0000876] property_value: homology_notes "In all vertebrates, the endodermal epithelium lining each pouch contacts the surface ectoderm of the clefts to form a series of bilayered branchial membranes, that break down in fish to form the gill openings.[well established][VHOG]" xsd:string {external_class="VHOG:0000876", ontology="VHOG", source="ISBN:978-0124020603 Kaufman MH and Bard JBL\, The anatomical basis of mouse development (1999) p.72", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0009217 name: pharyngeal membrane of 4th arch is_a: UBERON:0009210 ! pharyngeal membrane relationship: overlaps UBERON:0005875 ! 4th arch pharyngeal cleft relationship: overlaps UBERON:0007125 ! pharyngeal pouch 4 relationship: part_of UBERON:0003115 {source="EMAPA"} ! pharyngeal arch 4 xref: EMAPA:16763 ! branchial membrane of 4th arch synonym: "4th pharyngeal membrane" EXACT [UBERON:cjm] [Term] id: UBERON:0006212 name: bulbo-ventricular groove subset: emapa_ehdaa2 synonym: "bulbo-ventricular sulcus" EXACT [EMAPA:16693] synonym: "ependymal groove" EXACT [EMAPA:16693] synonym: "ependymal sulcus" EXACT [EMAPA:16693] xref: EMAPA:16693 ! bulboventricular groove xref: EHDAA2:0000195 ! bulbo-ventricular groove xref: EHDAA:766 ! bulbo-ventricular groove xref: VHOG:0001405 ! bulboventricular groove is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000948 ! heart synonym: "bulboventricular groove" EXACT [VHOG:0001405] [Term] id: UBERON:0006213 ! carpus cartilage condensation name: carpus cartilage condensation xref: EMAPA:18102 ! carpus cartilage condensation xref: EHDAA2:0000221 ! carpus cartilage condensation xref: VHOG:0001123 ! carpus cartilage condensation xref: EHDAA:8544 ! carpus cartilage condensation is_a: UBERON:0002050 ! embryonic structure intersection_of: UBERON:0005863 ! cartilagenous condensation intersection_of: develops_into UBERON:0001435 ! carpal bone relationship: develops_from UBERON:0006214 ! carpus pre-cartilage condensation def: "A cartilaginous condensation that develops_into a carpal bone." [OBOL:automatic] [Term] id: UBERON:0006214 name: carpus pre-cartilage condensation xref: EMAPA:17724 ! carpus pre-cartilage condensation xref: EHDAA2:0000222 ! carpus pre-cartilage condensation xref: VHOG:0000955 ! carpus pre-cartilage condensation xref: EHDAA:6324 ! carpus pre-cartilage condensation is_a: UBERON:0002050 ! embryonic structure intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0001435 ! carpal bone relationship: part_of UBERON:0009523 ! mesenchyme of handplate relationship: develops_from UBERON:0003319 ! mesenchyme of carpal region def: "A pre-cartilage condensation that develops_into a carpal bone." [OBOL:automatic] [Term] id: UBERON:0010540 name: tarsus pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0001447 ! tarsal bone relationship: part_of UBERON:0003328 ! mesenchyme of footplate relationship: part_of UBERON:0001445 {source="EHDAA2"} ! skeleton of pes relationship: part_of UBERON:0004454 ! tarsal region relationship: develops_from UBERON:0010695 ! mesenchyme of tarsal region xref: EHDAA2:0001978 ! tarsus pre-cartilage condensation def: "A pre-cartilage condensation that develops_into a tarsal bone." [OBOL:automatic] [Term] id: UBERON:0010541 ! tarsus cartilage condensation name: tarsus cartilage condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0001447 ! tarsal bone relationship: part_of UBERON:0003328 {source="EHDAA2"} ! mesenchyme of footplate relationship: part_of UBERON:0001445 {source="EHDAA2"} ! skeleton of pes relationship: part_of UBERON:0004454 ! tarsal region relationship: develops_from UBERON:0010540 {source="EHDAA2"} ! tarsus pre-cartilage condensation xref: EHDAA2:0001977 ! tarsus cartilage condensation def: "A cartilaginous condensation that develops_into a tarsal bone." [OBOL:automatic] [Term] id: UBERON:0013163 name: future cerebellum is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0010092 {source="EHDAA2"} ! future metencephalon intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: develops_into UBERON:0002037 ! cerebellum synonym: "cerebellum primordium" EXACT [EHDAA2:0000231] xref: EHDAA2:0000231 ! cerebellum primordium xref: EMAPA:17074 ! cerebellum primordium [Term] id: UBERON:0006215 name: rhombic lip def: "Rhombic lips are a posterior section of the developing metencephalon within an embryo. They extend posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cells and contain cerebellar precursor cells, among others" [Wikipedia:Rhombic_lips] subset: vertebrate_core synonym: "dorsal part of alar plate of metencephalon" RELATED [EMAPA:17074] synonym: "cerebellum primordium" RELATED [EMAPA:17074] xref: ZFA:0001440 ! rhombic lip is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0002028 {source="ZFA"} ! hindbrain relationship: part_of UBERON:0010092 {source="Wikipedia"} ! future metencephalon xref: XAO:0004135 ! rhombic lip xref: TAO:0001440 ! rhombic lip property_value: external_definition "The interface between the dorsal neuroepithelium and the roofplate of the fourth ventricle. The source of a number of migratory neuron populations of the hindbrain.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001440", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:0009840 name: lower rhombic lip def: "Posterior portion of the rhombic lip contained within rhombomeres 2-8. Gives rise to several brainstem nuclei and choroid plexus." [ZFIN:curator] synonym: "caudal rhombic lip" EXACT [UBERON:cjm] xref: TAO:0001441 ! lower rhombic lip is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: overlaps UBERON:0005519 {source="ZFA"} ! rhombomere 6 relationship: overlaps UBERON:0005527 {source="ZFA"} ! rhombomere 8 relationship: overlaps UBERON:0005569 {source="ZFA"} ! rhombomere 2 relationship: overlaps UBERON:0005515 {source="ZFA"} ! rhombomere 5 relationship: overlaps UBERON:0005507 {source="ZFA"} ! rhombomere 3 relationship: overlaps UBERON:0005523 {source="ZFA"} ! rhombomere 7 relationship: overlaps UBERON:0005511 {source="ZFA"} ! rhombomere 4 relationship: part_of UBERON:0006215 {source="ZFA"} ! rhombic lip xref: ZFA:0001441 ! lower rhombic lip [Term] id: UBERON:0009841 ! upper rhombic lip name: upper rhombic lip def: "Anterior-most region of dorsal hindbrain within rhombomere 1, adjacent the midbrain-hindbrain boundary." [ZFIN:curator] synonym: "rostral rhombic lip" EXACT [DHB:URL] synonym: "cerebellar anlage" EXACT [ZFA:0001442] synonym: "presumptive cerebellum" EXACT [ZFA:0001442] xref: TAO:0001442 ! upper rhombic lip is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure relationship: part_of UBERON:0005499 {source="ZFA"} ! rhombomere 1 relationship: part_of UBERON:0006215 {source="ZFA"} ! rhombic lip relationship: adjacent_to UBERON:0003052 {source="ZFA-def"} ! midbrain-hindbrain boundary xref: ZFA:0001442 ! upper rhombic lip [Term] id: UBERON:0006216 name: cervical sinus def: "a temporary depression caudal to the second pharyngeal arch, containing the succeeding pharyngeal arches; it is overgrown by the second pharyngeal arch and closes off as the cervical vesicle[TFD]." [Wikipedia:Cervical_sinus, http://medical-dictionary.thefreedictionary.com/cervical+sinus] comment: This sinus is bounded in front by the hyoid arch, and behind by the thoracic wall; it is ultimately obliterated by the fusion of its walls. synonym: "sinus cervicalis" EXACT [Wikipedia:Cervical_sinus] subset: emapa_ehdaa2 xref: EMAPA:17526 ! cervical sinus of skin of integumental system xref: RETIRED_EHDAA2:0000239 ! cervical sinus is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0008814 ! pharyngeal system xref: EHDAA2:0000078 ! cervical sinus xref: EHDAA:5105 ! cervical sinus xref: EHDAA:6534 ! cervical sinus synonym: "sinus cervicalis" RELATED LATIN [Wikipedia:Cervical_sinus] xref: http://upload.wikimedia.org/wikipedia/commons/2/20/Kiemenbogen.jpg [Term] id: UBERON:0006218 name: common atrial chamber subset: emapa_ehdaa2 xref: EMAPA:16225 ! common atrial chamber of primitive heart tube xref: EMAPA:16342 ! common atrial chamber of heart xref: EMAPA:16689 ! common atrial chamber of atrium xref: RETIRED_EHDAA2:0000268 ! common atrial chamber xref: EHDAA:1267 ! common atrial chamber of atrium is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0002081 ! cardiac atrium [Term] id: UBERON:0006219 name: deltoid pre-muscle mass subset: emapa_ehdaa2 xref: EMAPA:17749 ! deltoid pre-muscle mass xref: EHDAA2:0000340 ! deltoid pre-muscle mass xref: EHDAA:6002 ! deltoid pre-muscle mass is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group [Term] id: UBERON:0006222 name: future diencephalon subset: emapa_ehdaa2 subset: vertebrate_core xref: EMAPA:16514 ! future diencephalon xref: RETIRED_EHDAA2:0000386 ! future diencephalon xref: ZFA:0000574 ! presumptive diencephalon xref: EHDAA:844 ! future diencephalon xref: EFO:0003442 ! presumptive diencephalon is_a: UBERON:0002050 ! embryonic structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: develops_into UBERON:0001894 ! diencephalon xref: EHDAA2:0000600 ! future diencephalon xref: TAO:0000574 ! presumptive diencephalon synonym: "presumptive diencephalon" EXACT [TAO:0000574] def: "A multi-tissue structure that develops_into a diencephalon." [OBOL:automatic] [Term] id: UBERON:0010288 ! future medulla oblongata name: future medulla oblongata is_a: UBERON:0002050 ! embryonic structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: develops_into UBERON:0001896 ! medulla oblongata xref: EHDAA2:0001088 ! medulla oblongata (also: UBERON:0001896 'medulla oblongata') def: "A multi-tissue structure that develops_into a medulla oblongata." [OBOL:automatic] [Term] id: UBERON:0006223 name: dorsal meso-oesophagus subset: emapa_ehdaa2 xref: EMAPA:16704 ! dorsal meso-oesophagus of mesentery of oesophageal region xref: EMAPA:16837 ! dorsal meso-oesophagus of mesentery of oesophagus of foregut xref: EMAPA:18865 ! dorsal meso-oesophagus of mesentery of oesophagus of gut xref: RETIRED_EHDAA2:0000412 ! dorsal meso-oesophagus xref: MA:0001570 ! dorsal meso-esophagus xref: EHDAA:2945 ! dorsal meso-oesophagus is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0003283 ! mesentery of oesophagus synonym: "dorsal meso-esophagus" EXACT [MA:0001570] [Term] id: UBERON:0006224 name: elbow joint primordium subset: emapa_ehdaa2 xref: EMAPA:17710 ! elbow joint primordium xref: EHDAA2:0000431 ! elbow joint primordium xref: EHDAA:8483 ! elbow joint primordium is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0003318 ! mesenchyme of elbow relationship: develops_into UBERON:0001490 ! elbow joint [Term] id: UBERON:0006226 name: endolymphatic appendage subset: emapa_ehdaa2 xref: EMAPA:16994 ! endolymphatic appendage of otocyst xref: EMAPA:17283 ! endolymphatic appendage of inner ear xref: EHDAA2:0000437 ! endolymphatic appendage xref: VHOG:0000373 ! endolymphatic appendage is_a: UBERON:0002050 ! embryonic structure property_value: external_definition "An outgrowth of the otic vesicle that forms the endolymphatic duct and sac during embryonic development. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000373", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/endolymphatic+appendage", source="http://bgee.unil.ch/"} [Term] id: UBERON:0010752 ! exoccipital cartilage condensation name: exoccipital cartilage condensation is_a: UBERON:0005863 ! cartilagenous condensation relationship: part_of UBERON:0002241 {source="EMAPA"} ! chondrocranium relationship: develops_from UBERON:0006228 ! exoccipital pre-cartilage condensation relationship: develops_into UBERON:0001693 ! exoccipital bone xref: EMAPA:18339 ! exoccipital cartilage condensation [Term] id: UBERON:0006228 ! exoccipital pre-cartilage condensation name: exoccipital pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:18014 ! exoccipital pre-cartilage condensation xref: EHDAA2:0000457 ! exoccipital pre-cartilage condensation xref: VHOG:0000963 ! exoccipital pre-cartilage condensation xref: EHDAA:8355 ! exoccipital pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: develops_into UBERON:0001693 ! exoccipital bone relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium [Term] id: UBERON:0006231 name: facial bone primordium subset: emapa_ehdaa2 comment: Editor notes: check this for developmental relationships synonym: "facial bones primordia" EXACT [EHDAA2:0000488] synonym: "facial skeleton primordium" RELATED [] synonym: "viscerocranium primordium" RELATED [] xref: EMAPA:18024 ! facial bones primordia xref: EHDAA2:0000488 ! facial bones primordia xref: EHDAA:9552 ! facial bones primordia is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0007842 {source="EHDAA2"} ! membrane bone relationship: part_of UBERON:0011156 {source="EHDAA2"} ! facial skeleton [Term] id: UBERON:0010129 ! femur cartilage condensation name: femur cartilage condensation comment: TODO - request EHDAA2 synonym: "femoral cartilage condensation" EXACT [EMAPA:17742] xref: EMAPA:17742 ! femur cartilage condensation is_a: UBERON:0005863 ! cartilagenous condensation relationship: develops_into UBERON:0000981 ! femur relationship: develops_from UBERON:0006234 ! femur pre-cartilage condensation relationship: part_of UBERON:0005254 {source="EMAPA"} ! upper leg mesenchyme [Term] id: UBERON:0006234 name: femur pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:17502 ! femur pre-cartilage condensation xref: EHDAA2:0000508 ! femur pre-cartilage condensation xref: VHOG:0000951 ! femur pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: develops_into UBERON:0000981 ! femur [Term] id: UBERON:0006235 name: foregut-midgut junction subset: emapa_ehdaa2 xref: EMAPA:16363 ! foregut-midgut junction xref: EHDAA2:0000569 ! foregut-midgut junction xref: VHOG:0000291 ! foregut-midgut junction xref: EHDAA:526 ! foregut-midgut junction intersection_of: UBERON:0000015 ! anatomical boundary intersection_of: adjacent_to UBERON:0001041 ! foregut intersection_of: adjacent_to UBERON:0001045 ! midgut relationship: part_of UBERON:0001555 ! digestive tract property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[well established][VHOG]" xsd:string {external_class="VHOG:0000291", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "An anatomical boundary that adjacent_to a foregut and adjacent_to a midgut." [OBOL:automatic] [Term] id: UBERON:0013158 name: foregut-midgut junction gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0006235 ! foregut-midgut junction xref: EHDAA2:0000574 ! foregut-midgut junction gland xref: EMAPA:17065 ! gland of foregut-midgut junction synonym: "gland of foregut-midgut junction" EXACT [EMAPA:17065] [Term] id: UBERON:0006236 name: frontal bone primordium subset: emapa_ehdaa2 xref: EMAPA:18017 ! frontal bone primordium xref: EHDAA2:0000577 ! frontal bone primordium xref: EHDAA:9540 ! frontal bone primordium is_a: UBERON:0002050 ! embryonic structure [Term] id: UBERON:0006239 name: future central tendon subset: emapa_ehdaa2 xref: EMAPA:25035 ! future central tendon xref: EHDAA2:0000593 ! future central tendon xref: EHDAA:4118 ! future central tendon is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo intersection_of: UBERON:0000043 ! tendon intersection_of: develops_into UBERON:0006670 ! central tendon def: "A tendon that develops_into a central tendon." [OBOL:automatic] [Term] id: UBERON:0006241 ! future spinal cord name: future spinal cord subset: vertebrate_core xref: EMAPA:16092 ! future spinal cord of neural ectoderm of ectoderm of embryo xref: EMAPA:16525 ! future spinal cord of central nervous system of nervous system of organ system xref: EMAPA:16755 ! future spinal cord of central nervous system of nervous system of tail of embryo xref: EHDAA2:0000674 ! future spinal cord xref: ZFA:0000417 ! presumptive spinal cord xref: EHDAA:898 ! future spinal cord of central nervous system xref: EFO:0003438 ! presumptive spinal cord synonym: "presumptive spinal cord" EXACT [ZFA:0000417] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001017 ! central nervous system relationship: develops_into UBERON:0002240 ! spinal cord relationship: develops_into UBERON:0001049 {source="EHDAA2"} ! neural tube xref: TAO:0000417 ! presumptive spinal cord synonym: "presumptive spinal cord neural keel" EXACT [TAO:0000417] synonym: "presumptive spinal cord neural plate" EXACT [TAO:0000417] synonym: "presumptive spinal cord neural rod" EXACT [TAO:0000417] [Term] id: UBERON:0006242 name: gall bladder primordium subset: emapa_ehdaa2 xref: EMAPA:16713 ! gall bladder primordium of biliary bud xref: EMAPA:16842 ! gall bladder primordium of liver and biliary system xref: EHDAA2:0000700 ! gall bladder primordium xref: EHDAA:3047 ! gall bladder primordium is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0002423 ! hepatobiliary system relationship: develops_into UBERON:0002110 ! gallbladder relationship: part_of UBERON:0004912 ! biliary bud xref: XAO:0004205 ! gall bladder primordium [Term] id: UBERON:0006243 name: glossopharyngeal IX preganglion subset: emapa_ehdaa2 xref: EMAPA:16661 ! glossopharyngeal IX preganglion xref: RETIRED_EHDAA2:0000713 ! glossopharyngeal IX preganglion xref: EHDAA:1479 ! glossopharyngeal IX preganglion is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001714 ! cranial ganglion [Term] id: UBERON:0006244 ! hip joint primordium name: hip joint primordium subset: emapa_ehdaa2 xref: EMAPA:17739 ! hip joint primordium xref: EHDAA2:0000785 ! hip joint primordium xref: EHDAA:8462 ! hip joint primordium is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0003320 ! mesenchyme of hip relationship: develops_into UBERON:0001486 ! hip joint [Term] id: UBERON:0006245 name: humerus cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:17713 ! humerus cartilage condensation xref: EHDAA2:0000787 ! humerus cartilage condensation xref: VHOG:0001120 ! humerus cartilage condensation xref: EHDAA:6240 ! humerus cartilage condensation is_a: UBERON:0005863 ! cartilagenous condensation relationship: develops_from UBERON:0006246 {source="EHDAA2"} ! humerus pre-cartilage condensation relationship: develops_into UBERON:0000976 ! humerus relationship: part_of UBERON:0005258 {source="EHDAA2"} ! upper arm mesenchyme relationship: part_of UBERON:0001440 {source="EHDAA2"} ! forelimb skeleton [Term] id: UBERON:0006246 name: humerus pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:17427 ! humerus pre-cartilage condensation xref: EHDAA2:0000788 ! humerus pre-cartilage condensation xref: VHOG:0000950 ! humerus pre-cartilage condensation xref: EHDAA:4192 ! humerus pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0005258 {source="EHDAA2"} ! upper arm mesenchyme relationship: part_of UBERON:0001440 {source="EHDAA2"} ! forelimb skeleton relationship: develops_into UBERON:0000976 ! humerus [Term] id: UBERON:0006247 name: iliac pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:18029 ! iliac pre-cartilage condensation xref: EHDAA2:0000809 ! iliac pre-cartilage condensation xref: EHDAA:9568 ! iliac cartilage condensation xref: VHOG:0000964 ! iliac pre-cartilage condensation is_a: UBERON:0005863 ! cartilagenous condensation relationship: part_of UBERON:0007832 {source="EHDAA2"} ! pelvic girdle skeleton relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme [Term] id: UBERON:0010714 ! iliac cartilage condensation name: iliac cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0006247 {source="EHDAA2"} ! iliac cartilage condensation relationship: part_of UBERON:0007832 {source="EHDAA2"} ! pelvic girdle skeleton xref: EHDAA2:0000808 ! iliac cartilage condensation xref: EMAPA:18347 ! iliac cartilage condensation xref: VHOG:0001126 ! iliac cartilage condensation [Term] id: UBERON:0010718 ! pubic cartilage condensation name: pubic cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0006285 {source="EHDAA2"} ! pubic cartilage condensation relationship: part_of UBERON:0007832 {source="EHDAA2"} ! pelvic girdle skeleton xref: EHDAA2:0001573 ! pubic cartilage condensation [Term] id: UBERON:0006285 name: pubic pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:26928 ! pubic cartilage condensation xref: EMAPA:18349 ! pubic pre-cartilage condensation xref: EHDAA2:0001574 ! pubic pre-cartilage condensation xref: EHDAA:9572 ! pubic cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: part_of UBERON:0007832 {source="EHDAA2"} ! pelvic girdle skeleton xref: EHDAA2:0001574 ! pubic pre-cartilage condensation xref: VHOG:0000965 ! pubic pre-cartilage condensation [Term] id: UBERON:0006262 ! malleus pre-cartilage condensation name: malleus pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:17826 ! malleus pre-cartilage condensation xref: EHDAA2:0001055 ! malleus pre-cartilage condensation xref: VHOG:0000958 ! malleus pre-cartilage condensation xref: EHDAA:9026 ! malleus pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0003107 {source="EHDAA2"} ! Meckel's cartilage [Term] id: UBERON:0010054 ! malleus cartilage condensation name: malleus cartilage condensation is_a: UBERON:0005863 ! cartilagenous condensation relationship: develops_from UBERON:0006262 ! malleus pre-cartilage condensation xref: EMAPA:18229 ! malleus cartilage condensation [Term] id: UBERON:0006294 name: stapes pre-cartilage condensation comment: independent of the mesenchymal condensation that will form the otic capsule subset: emapa_ehdaa2 synonym: "stapedial anlage" EXACT [doi:10.1111/j.1469-7580.2005.00441.x] xref: EMAPA:17827 ! stapes pre-cartilage condensation xref: EHDAA2:0001910 ! stapes pre-cartilage condensation xref: VHOG:0000956 ! stapes pre-cartilage condensation xref: EHDAA:5699 ! stapes pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0005689 {source="EHDAA2", notes="cranial end", source="doi:10.1111/j.1469-7580.2005.00441.x"} ! 2nd arch mesenchyme relationship: part_of UBERON:0001686 {source="EHDAA2"} ! auditory ossicle [Term] id: UBERON:0010055 ! stapes cartilage condensation name: stapes cartilage condensation comment: Editor notes: TODO - check relationship to Recihert's. Taxon notes: The stapes is homologous to the hyomandibula. In this ontology, we use the class 'hyomandibular cartilage' generally to include the future stapes, the future hyomandibular bone of teleosts and the unossified cartilage in sharks. is_a: UBERON:0005863 ! cartilagenous condensation is_a: UBERON:0011607 {source="http://people.eku.edu/ritchisong/342notes4.htm"} ! hyomandibular cartilage relationship: develops_from UBERON:0006294 ! stapes pre-cartilage condensation relationship: part_of UBERON:0001686 ! auditory ossicle xref: EMAPA:18230 ! stapes cartilage condensation [Term] id: UBERON:0006248 ! incus pre-cartilage condensation name: incus pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:17825 ! incus pre-cartilage condensation xref: EHDAA2:0000813 ! incus pre-cartilage condensation xref: VHOG:0000957 ! incus pre-cartilage condensation xref: EHDAA:9024 ! incus pre-cartilage condensation is_a: UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0010042 {source="EHDAA2-generalized"} ! 1st arch mesenchyme [Term] id: UBERON:0007374 ! incus cartilage condensation name: incus cartilage condensation xref: EMAPA:18228 ! incus cartilage condensation is_a: UBERON:0005863 ! cartilagenous condensation relationship: develops_from UBERON:0006248 ! incus pre-cartilage condensation [Term] id: UBERON:0006251 name: interparietal bone primordium subset: emapa_ehdaa2 xref: EMAPA:18018 ! inter-parietal bone primordium xref: EHDAA2:0000881 ! interparietal bone primordium is_a: UBERON:0001048 ! primordium relationship: develops_into UBERON:0002229 ! interparietal bone [Term] id: UBERON:0006253 name: embryonic intraretinal space subset: emapa_ehdaa2 synonym: "retina intraretinal space" EXACT [VHOG:0000534] synonym: "intraretinal space" EXACT [EHDAA2:0000889] synonym: "intraretinal space of retina" EXACT [EMAPA:17170] xref: EMAPA:16676 ! intraretinal space of optic cup xref: EMAPA:17170 ! intraretinal space of retina xref: EHDAA2:0000889 ! intraretinal space xref: VHOG:0000534 ! retina intraretinal space xref: EHDAA:4761 ! intraretinal space of retina is_a: UBERON:0012467 {source="EHDAA2"} ! enclosed anatomical space relationship: part_of UBERON:0000966 ! retina relationship: part_of UBERON:0000922 ! embryo property_value: external_definition "The space separating the outer pigment epithelium and the inner neural retina of the optic cup and of the retina. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000534", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/intraretinal+space", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {external_class="VHOG:0000534", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006254 name: ischial cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:26930 ! ischial cartilage condensation xref: EHDAA2:0000890 ! ischial cartilage condensation xref: EHDAA:9570 ! ischial cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: part_of UBERON:0007832 {source="EHDAA2"} ! pelvic girdle skeleton relationship: develops_from UBERON:0006255 {source="EHDAA2"} ! ischial pre-cartilage condensation [Term] id: UBERON:0006255 ! ischial pre-cartilage condensation name: ischial pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:18348 ! ischial pre-cartilage condensation xref: EHDAA2:0000891 ! ischial pre-cartilage condensation xref: VHOG:0000962 ! ischial pre-cartilage condensation xref: EHDAA:7153 ! ischial pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: part_of UBERON:0007832 {source="EHDAA2"} ! pelvic girdle skeleton [Term] id: UBERON:0006256 name: knee joint primordium subset: emapa_ehdaa2 xref: EMAPA:17740 ! knee joint primordium xref: EHDAA2:0000897 ! knee joint primordium xref: EHDAA:8467 ! knee joint primordium is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0003321 ! mesenchyme of knee relationship: develops_into UBERON:0001485 ! knee joint [Term] id: UBERON:0006257 name: laryngotracheal groove def: "a groove in the floor of the pharynx formed from the ventral diverticulum of endoderm that arises from the floor of the foregut caudal to the pharynx. This structure is the precursor for the larynx and trachea[WP,edited]." [Wikipedia:Laryngotracheal_groove, http://isc.temple.edu/marino/embryology/resp98/respdev.htm] comment: Editor notes: Note we currently have pharynx as part of the upper respiratory tract - separate by development? synonym: "laryngo-tracheal tube" RELATED [Wikipedia:Laryngotracheal_groove] synonym: "laryngo-tracheal groove" EXACT [EHDAA2:0004073] synonym: "laryngotracheal endoderm" RELATED [] synonym: "sulcus laryngotrachealis" EXACT LATIN [Wikipedia:Laryngotracheal_groove] xref: EMAPA:16739 ! laryngo-tracheal groove xref: RETIRED_EHDAA2:0000909 ! laryngo-tracheal groove is_a: UBERON:0006846 {source="EHDAA2"} ! groove relationship: part_of UBERON:0001041 {source="EHDAA2"} ! foregut relationship: part_of UBERON:0001558 {source="EHDAA2"} ! lower respiratory tract relationship: part_of UBERON:0000922 ! embryo xref: EHDAA2:0004073 ! laryngo-tracheal groove xref: SCTID:361426003 ! Laryngotracheal groove xref: VHOG:0001404 ! laryngo-tracheal groove xref: EHDAA:1005 ! laryngo-tracheal groove xref: ncithesaurus:Laryngotracheal_Tube ! laryngotracheal tube property_value: homology_notes "Lung development begins with the appearance of the laryngotracheal groove, which is a small diverticulum that arises from the floor of the primitive pharynx at E9 in mouse and 4 wk in human.[well established][VHOG]" xsd:string {external_class="VHOG:0001404", ontology="VHOG", source="PMID:15817505 Warburton D\, Bellusci S\, De Langhe S\, Del Moral PM\, Fleury V\, Mailleux A\, Tefft D\, Unbekandt M\, Wang K\, Shi W\, Molecular mechanisms of early lung specification and branching morphogenesis. Pediatric Research (2005)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1283960 [Term] id: UBERON:0006259 name: lens pit def: "a pitlike depression in the ectoderm of the lens placode where the primordial lens is developing[TFD]." [http://medical-dictionary.thefreedictionary.com/lens+pit] subset: emapa_ehdaa2 xref: EMAPA:16799 ! lens pit xref: EHDAA2:0000981 ! lens pit xref: VHOG:0000806 ! lens pit xref: EHDAA:3809 ! lens pit is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0000965 ! lens xref: ncithesaurus:Lens_Pit ! Lens Pit property_value: external_definition "A pitlike depression in the ectoderm of the lens placode where the primordial lens is developing. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000806", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/lens+pit", source="http://bgee.unil.ch/"} xref: UMLS:C1517769 [Term] id: UBERON:0006260 name: lingual swellings comment: the collection consisting of the two lateral swellings and the medial swelling subset: emapa_ehdaa2 synonym: "lingual swelling" RELATED [EHDAA2:0000996] xref: EMAPA:17186 ! lingual swelling xref: EHDAA2:0000996 ! lingual swelling xref: VHOG:0000449 ! lingual swelling is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance relationship: part_of UBERON:0010056 {source="EHDAA2"} ! future tongue relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 property_value: external_definition "Primordium of the tongue; the median swelling and the distal and proximal swellings arise from the ventral aspect of the stomodeum. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000449", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/lingual+swellings", source="http://bgee.unil.ch/"} property_value: homology_notes "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {external_class="VHOG:0000449", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x Iwasaki S\, Evolution of the structure and function of the vertebrate tongue. J Anat (2002)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006756 name: median lingual swelling def: "During the third week of embryological development there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings which rise from the inner surface of the mandibular arch and meet in the middle line. The site of their meeting remains post-embryonically as the median sulcus of the tongue. The tuberculum impar is said to form the central part of the tongue immediately in front of the foramen cecum, but Hammar insists that it is purely a transitory structure and forms no part of the adult tongue[WP, Gray's]." [Wikipedia:Tuberculum_impar] comment: The thyroid initially develops caudal to the tuberculum impar . This embryonic swelling arises from the first pharyngeal arch and occurs midline on the floor of the developing pharynx, eventually helping form the tongue as the 2 lateral lingual swellings overgrow it. [http://emedicine.medscape.com/article/845125-overview] synonym: "median tongue bud" EXACT [http://emedicine.medscape.com/article/845125-overview] synonym: "median lingual swelling" EXACT [EHDAA2:0001081] synonym: "tuberculum impar" EXACT [] synonym: "tuberculum linguale mediale" EXACT [Wikipedia:Tuberculum_impar] xref: EMAPA:17187 ! median xref: EHDAA2:0001081 ! median lingual swelling xref: VHOG:0000730 ! median lingual swelling is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0006260 {source="EHDAA2"} ! lingual swellings relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 xref: SCTID:308821003 ! Entire tuberculum impar xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray979.png property_value: homology_notes "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {external_class="VHOG:0000730", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006757 name: lateral lingual swelling def: "During the third week there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings (or distal tongue bud) which rise from the inner surface of the mandibular arch and meet in the middle line." [Wikipedia:Lateral_lingual_swelling] comment: Structure notes: paired synonym: "lateral swellings" RELATED [Wikipedia:Lateral_lingual_swelling] synonym: "tuberculum laterale" RELATED [Wikipedia:Lateral_lingual_swelling] synonym: "lateral lingual prominence" RELATED [] xref: EHDAA2:0000911 ! lateral lingual swelling xref: EMAPA:17189 ! lateral of lingual swelling xref: VHOG:0000731 ! lateral lingual swelling is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0006260 ! lingual swellings relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 synonym: "tuberculum linguale laterale" RELATED LATIN [Wikipedia:Lateral_lingual_swelling] xref: http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray979.png property_value: homology_notes "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {external_class="VHOG:0000731", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x Iwasaki S\, Evolution of the structure and function of the vertebrate tongue. J Anat (2002)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0010056 name: future tongue is_a: UBERON:0003103 {source="EHDAA2"} ! compound organ is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000166 {source="EHDAA2"} ! oral opening relationship: part_of UBERON:0001042 {source="EHDAA"} ! chordate pharynx intersection_of: UBERON:0003103 ! compound organ intersection_of: develops_into UBERON:0001723 ! tongue xref: EHDAA2:0000696 ! future tongue xref: EHDAA:2951 ! future tongue def: "A compound organ that develops_into a tongue." [OBOL:automatic] [Term] id: UBERON:0010057 name: hypopharyngeal eminence is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance relationship: part_of UBERON:0010056 {source="EHDAA2"} ! future tongue xref: EHDAA2:0000799 ! hypopharyngeal eminence xref: EMAPA:17352 ! hypobranchial eminence xref: SCTID:361420009 ! Hypobranchial eminence synonym: "hypobranchial eminence" EXACT [EMAPA:17352, OBOL:automatic] [Term] id: UBERON:0010059 name: hypoglossal cord is_a: UBERON:0002036 {source="EHDAA2"} ! striated muscle tissue relationship: part_of UBERON:0010056 {source="EHDAA2"} ! future tongue xref: EHDAA2:0004610 ! hypoglossal cord [Term] id: UBERON:0010034 name: copula linguae def: "A single midventral prominence deriving from the ventral bases of pharyngeal arches 2, 3 and 4 - provides the covering of the posterior of the tongue //The furcula is at first separated from the tuberculum impar by a depression, but later by a ridge, the copula, formed by the forward growth and fusion of the ventral ends of the second, third, and part of the fourth branchial arches[WP]." [Wikipedia:Copula_linguae] comment: add new term for Hypobranchial_eminence? synonym: "copula" EXACT [EHDAA2:0004611] is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance relationship: part_of UBERON:0010056 {source="EHDAA2"} ! future tongue relationship: has_developmental_contribution_from UBERON:0002539 ! pharyngeal arch xref: EHDAA2:0004611 ! copula xref: SCTID:361424000 ! Copula synonym: "copula linguae" RELATED LATIN [Wikipedia:Copula_linguae] xref: http://upload.wikimedia.org/wikipedia/commons/8/85/Gray980.png [Term] id: UBERON:0006263 name: Meckel's cartilage pre-cartilage condensation subset: emapa_ehdaa2 comment: Development notes: NC contributes in EHDAA2. Todo: use EHDAA2 structure xref: EMAPA:17358 ! Meckel's cartilage pre-cartilage condensation xref: EHDAA2:0001074 ! Meckel's cartilage pre-cartilage condensation xref: VHOG:0001121 ! Meckel's cartilage pre-cartilage condensation is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0000922 ! embryo relationship: develops_into UBERON:0003107 ! Meckel's cartilage relationship: develops_from UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme relationship: develops_from UBERON:0002342 {source="UBERONREF:0000002"} ! neural crest [Term] id: UBERON:0006264 name: mouth-foregut junction subset: emapa_ehdaa2 xref: EMAPA:16258 ! mouth-foregut junction xref: RETIRED_EHDAA2:0001205 ! mouth-foregut junction xref: VHOG:0000592 ! mouth-foregut junction xref: EHDAA:534 ! mouth-foregut junction intersection_of: UBERON:0000015 ! anatomical boundary intersection_of: adjacent_to UBERON:0001041 ! foregut intersection_of: adjacent_to UBERON:0000165 ! mouth relationship: part_of UBERON:0005409 ! gastrointestinal system def: "An anatomical boundary that adjacent_to a mouth and adjacent_to a foregut." [OBOL:automatic] [Term] id: UBERON:0006266 ! nasolacrimal groove name: nasolacrimal groove def: "Groove between maxillary prominence and lateral nasal process." [Wikipedia:Lacrimal_groove, http://www.indiana.edu/~anat550/hnanim/face/face.html] comment: On the nasal surface of the body of the maxilla, in front of the opening of the sinus is a deep groove, the lacrimal groove (or lacrimal sulcus), which is converted into the nasolacrimal canal, by the lacrimal bone and inferior nasal concha; this canal opens into the inferior meatus of the nose and transmits the nasolacrimal duct[WP] See also: oblique facial cleft subset: emapa_ehdaa2 synonym: "naso-lacrimal groove" EXACT [EMAPA:16679] xref: EMAPA:16679 ! naso-lacrimal groove xref: EHDAA2:0001238 ! nasolacrimal groove xref: VHOG:0001307 ! nasolacrimal groove xref: EHDAA:4770 ! nasolacrimal groove is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0012313 {source="EHDAA2"} ! 1st arch maxillary ectoderm relationship: adjacent_to UBERON:0004067 ! lateral nasal prominence relationship: adjacent_to UBERON:0005868 ! maxillary prominence relationship: part_of UBERON:0000004 {source="EHDAA2"} ! olfactory apparatus relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0000922 ! embryo xref: ncithesaurus:Nasolacrimal_Groove ! Nasolacrimal Groove synonym: "s. lacrimalis maxillae" RELATED LATIN [Wikipedia:Lacrimal_groove] xref: http://upload.wikimedia.org/wikipedia/commons/3/3f/Gray163.png xref: UMLS:C1513875 [Term] id: UBERON:0006269 name: optic foramen subset: emapa_ehdaa2 xref: EMAPA:18716 ! optic foramen xref: EHDAA2:0001312 ! optic foramen xref: VHOG:0001408 ! optic foramen (also: UBERON:0005745 'optic canal') xref: EHDAA:10646 ! optic foramen (also: UBERON:0005745 'optic canal') is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0011156 ! facial skeleton property_value: external_definition "An aperture in the root of the lesser wing of the sphenoid bone transmitting the optic nerve. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001408", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/optic+foramen", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006270 name: optic pit def: "A small indentation in the central part of the optic placode." [VHOG:0001162] xref: EMAPA:16325 ! optic pit xref: EMAPA:16199 ! optic sulcus xref: RETIRED_EHDAA2:0001316 ! optic pit xref: EHDAA2:0004433 ! optic sulcus xref: VHOG:0001162 ! optic pit xref: EHDAA:944 ! optic pit xref: EHDAA:944 ! optic pit synonym: "optic sulcus" EXACT [EHDAA2:0004433] synonym: "optic evagination" RELATED [EMAPA:16199] is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000019 ! camera-type eye property_value: external_definition "A small indentation in the central part of the optic placode. [157-169, Mueller_F_and_ObRahilly_R, The_first_appearance_of_the_neural_tube_and_optic_primordium_in_the_human_embryo_at_stage_10._Anatomy_and_Embryology_(1985)_172][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001162", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes " (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles (reference 1); The first morphological sign of eye development in vertebrates is the bilateral evagination of diencephalon in the early neurula. In mammals, this is marked by the appearance of the optic pit, whereas in fish and amphibians a bulging of the optic primordia is observed. Continued evagination of the optic primordia leads to the formation of the optic vesicles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0001162", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429\, DOI:10.1146/annurev.cellbio.17.1.255 Chow RL and Lang RA\, Early eye development in vertebrates. Annual Review of Cell and Developmental Biology (2001)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006271 name: orbital fissure subset: emapa_ehdaa2 xref: EMAPA:18717 ! orbital fissure xref: EHDAA2:0001328 ! orbital fissure xref: EHDAA:10648 ! orbital fissure is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0011156 ! facial skeleton xref: SCTID:280546005 ! Orbital fissure [Term] id: UBERON:0006272 name: oronasal cavity def: "In humans, the oronasal membrane ruptures during the seventh week, producing a single, large oronasal cavity" [http://cwx.prenhall.com/bookbind/pubbooks/martini10/chapter24/custom3/deluxe-content.html] subset: emapa_ehdaa2 xref: EMAPA:17200 ! oronasal cavity xref: EHDAA2:0001331 ! oronasal cavity xref: VHOG:0001352 ! oronasal cavity xref: EHDAA:5882 ! oronasal cavity is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000166 ! oral opening relationship: developmentally_replaces UBERON:0009672 ! oronasal membrane [Term] id: UBERON:0006273 name: otic pit def: "The auditory pit, also known as the otic pit, is the first rudiment of the internal ear. It appears shortly after that of the eye, in the form of a patch of thickened ectoderm, the auditory plate, over the region of the hind-brain. The auditory plate becomes depressed and converted into the auditory pit (or otic pit)." [Wikipedia:Otic_pit] subset: emapa_ehdaa2 xref: EMAPA:16536 ! otic pit xref: EHDAA2:0001336 ! otic pit xref: VHOG:0001147 ! otic pit xref: EHDAA:929 ! otic pit is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo xref: ncithesaurus:Otic_Pit ! Otic Pit property_value: external_definition "A depression appearing in each otic placode, marking the beginnning of embryonic development of the internal ear. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001147", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/Otic+pit", source="http://bgee.unil.ch/"} xref: UMLS:C1518676 [Term] id: UBERON:0006274 name: parietal bone primordium subset: emapa_ehdaa2 xref: EMAPA:18019 ! parietal bone primordium xref: EHDAA2:0001404 ! parietal bone primordium xref: EHDAA:9544 ! parietal bone primordium is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0006275 name: pericardio-peritoneal canal subset: emapa_ehdaa2 xref: EMAPA:16282 ! pericardio-peritoneal canal xref: EHDAA2:0001440 ! pericardio-peritoneal canal xref: VHOG:0001498 ! pericardio-peritoneal canal xref: EHDAA:636 ! pericardio-peritoneal canal is_a: UBERON:0002050 ! embryonic structure relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: part_of UBERON:0003887 {source="EMAPA"} ! intraembryonic coelom xref: ncithesaurus:Pericardioperitoneal_Canal ! Pericardioperitoneal Canal xref: SCTID:361428002 ! Pericardioperitoneal canal synonym: "pericardio-peritoneal channel" RELATED [VHOG:0001498] property_value: external_definition "Each of the canal that connects the pericardial cavity with the peritoneal cavity and becomes a pleural cavity. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.42, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001498", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C1283967 [Term] id: UBERON:0006276 name: perioptic mesenchyme subset: emapa_ehdaa2 xref: EMAPA:17167 ! perioptic mesenchyme xref: RETIRED_EHDAA2:0001444 ! perioptic mesenchyme xref: EHDAA:4751 ! perioptic mesenchyme is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0006277 name: pleuropericardial canals subset: emapa_ehdaa2 xref: EMAPA:17704 ! pleuro-pericardial canal xref: EHDAA2:0001479 ! pleuropericardial canals xref: EHDAA:4122 ! pleuropericardial canals is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo xref: VHOG:0001497 ! pleuropericardial canal synonym: "pleuropericardial canal" EXACT [VHOG:0001497] synonym: "pleuropericardial channel" RELATED [VHOG:0001497] [Term] id: UBERON:0006278 name: pleuropericardial folds subset: emapa_ehdaa2 xref: EMAPA:17706 ! pleuro-pericardial folds xref: EHDAA2:0001480 ! pleuropericardial folds xref: EHDAA:4126 ! pleuropericardial folds is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo xref: VHOG:0001499 ! pleuropericardial folds synonym: "pleuropericardial membranes" RELATED [VHOG:0001499] property_value: external_definition "Each of the folds that grow out from the lateral part of the body wall. They fuse and meet with the dorsal and ventral mesentery of the foregut, separating the pleural cavities from the pericardial cavity. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.43-46, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001499", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes) Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {external_class="VHOG:0001499", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0006279 name: pleuroperitoneal canal subset: emapa_ehdaa2 xref: EMAPA:17707 ! pleuro-peritoneal canal of diaphragm xref: EMAPA:25031 ! pleuro-peritoneal canal of intraembryonic coelom xref: EHDAA2:0001481 ! pleuroperitoneal canal xref: EHDAA:4128 ! pleuroperitoneal canal is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo xref: SCTID:361413002 ! Pleuroperitoneal canal xref: VHOG:0001505 ! pleuroperitoneal canal synonym: "pleuroperitoneal channel" RELATED [VHOG:0001505] property_value: external_definition "Each of the canal that links the peritoneal cavity and the caudal part of a pleural cavity. [The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.46, see_Kaufman_MH_and_Bard_JBL][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001505", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006281 name: pre-hepatic part comment: was obsoleted as it had no definition and the name was unclear. May refer to part of inferior vena cava or pre-hepatic portal vein FMA:71904 is_obsolete: true consider: EMAPA:18422 ! pre-hepatic part xref: RETIRED_EHDAA2:0001492 ! pre-hepatic part consider: EHDAA:8701 ! pre-hepatic part consider: FMA:71904 ! pre-hepatic portal vein [Term] id: UBERON:0006282 name: primary head vein subset: emapa_ehdaa2 comment: early vein that gives rise to various sinuses xref: EMAPA:16242 ! primary head vein xref: EHDAA2:0001498 ! primary head vein xref: EHDAA:818 ! primary head vein is_a: UBERON:0001638 {source="EHDAA2"} ! vein relationship: part_of UBERON:0009141 {source="EHDAA2"} ! craniocervical region vein relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004581 ! systemic venous system [Term] id: UBERON:0006283 name: primitive ventricle of heart def: "The embryonic ventricle or primitive ventricle of the developing heart gives rise to the trabeculated parts of the left and right ventricles. In contrast, the smooth parts of the left and right ventricles originate from the embryological bulbus cordis. The primitive ventricle becomes divided by a septum, the septum inferius or ventricular septum, which grows upward from the lower part of the ventricle, its position being indicated on the surface of the heart by a furrow. Its dorsal part increases more rapidly than its ventral portion, and fuses with the dorsal part of the septum intermedium. For a time an interventricular foramen exists above its ventral portion, but this foramen is ultimately closed by the fusion of the aortic septum with the ventricular septum." [Wikipedia:Embryonic_ventricle] subset: emapa_ehdaa2 synonym: "primitive ventricle" EXACT [EHDAA2:0001531] synonym: "future heart ventricle" EXACT [] synonym: "early heart ventricle" EXACT [] synonym: "embryonic heart ventricle" EXACT [] synonym: "embryonic ventricle" BROAD [] xref: EMAPA:16233 ! primitive ventricle of primitive heart tube xref: EMAPA:16350 ! primitive ventricle of heart xref: EHDAA2:0001531 ! primitive ventricle is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0005498 {source="EMAPA"} ! primitive heart tube xref: SCTID:361524003 ! Primitive ventricle [Term] id: UBERON:0009676 name: early telencephalic vesicle synonym: "early telencephalic ventricle" RELATED [] synonym: "early telencephalic vesicle" EXACT [EHDAA2:0001981] is_a: UBERON:0013150 ! future brain vesicle relationship: develops_from UBERON:0006284 {source="EHDAA2"} ! prosencephalic vesicle relationship: located_in UBERON:0001893 {source="EHDAA2"} ! telencephalon xref: EHDAA2:0001981 ! telencephalic vesicle xref: EHDAA:1993 ! telencephalic vesicle xref: EHDAA:2671 ! telencephalic vesicle xref: EMAPA:16914 ! telencephalic vesicle of telencephalon of forebrain xref: EFO:0003562 ! telencephalic ventricle [Term] id: UBERON:0006284 name: early prosencephalic vesicle def: "future brain vesicle that gives rise to telencephalic ventricle/lateral ventricles and 3rd ventricle" [UBERON:cjm] xref: EMAPA:16521 ! prosencephalic vesicle xref: EHDAA2:0001571 ! prosencephalic vesicle xref: VHOG:0000644 ! prosencephalic vesicle xref: EHDAA:1356 ! prosencephalic vesicle xref: SCTID:361480006 ! Forebrain vesicle xref: ZFA:0001259 ! forebrain ventricle xref: TAO:0001259 ! forebrain ventricle is_a: UBERON:0013150 ! future brain vesicle relationship: located_in UBERON:0006240 {source="EHDAA2"} ! future forebrain synonym: "prosencephalic vesicle" EXACT [EHDAA2:0001571] synonym: "forebrain ventricle" RELATED [VHOG:0000644] synonym: "forebrain vesicle" RELATED [VHOG:0000644] synonym: "prosencephalic ventricle" RELATED [VHOG:0000644] property_value: homology_notes "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {external_class="VHOG:0000644", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF\, Developmental Biology (2006) p.381-382\, ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0013147 name: early mesencephalic vesicle comment: gives rise to midbrain vesicle which gives rise to cerebral aqueduct is_a: UBERON:0013150 ! future brain vesicle relationship: located_in UBERON:0009616 {source="EHDAA2"} ! presumptive midbrain synonym: "mesencephalic vesicle" EXACT [EHDAA2:0001102] xref: EHDAA2:0001102 ! mesencephalic vesicle xref: EMAPA:16515 ! 3rd ventricle of future diencephalon [Term] id: UBERON:0013148 name: early midbrain vesicle comment: develops into cerebral aqueduct is_a: UBERON:0013150 ! future brain vesicle relationship: develops_from UBERON:0013147 {source="EHDAA2"} ! mesencephalic vesicle relationship: part_of UBERON:0001891 {source="EHDAA2"} ! midbrain synonym: "midbrain vesicle" EXACT [EHDAA2:0001103] xref: EHDAA2:0001103 ! midbrain vesicle xref: SCTID:361481005 ! Midbrain vesicle xref: EMAPA:16642 ! 3rd ventricle of diencephalon of future forebrain [Term] id: UBERON:0009131 name: obsolete midbrain vesicle comment: Obsoleted as the meaning of the class was unclear in earlier versions of EHDAA2 is_obsolete: true consider: SCTID:361481005 ! Midbrain vesicle consider: EHDAA2:0001103 ! midbrain vesicle [Term] id: UBERON:0013149 name: hindbrain vesicle comment: gives rise of 4th ventricle synonym: "rhombencephalic vesicle" EXACT [EHDAA2:0000101] is_a: UBERON:0013150 ! future brain vesicle relationship: located_in UBERON:0007277 {source="EHDAA2"} ! presumptive hindbrain xref: EHDAA2:0000101 ! rhombencephalic vesicle xref: SCTID:361482003 ! Hindbrain vesicle xref: EMAPA:16479 ! 4th ventricle [Term] id: UBERON:0013150 name: future brain vesicle comment: todo - resolve space vs structure inconsistency; consider adding all secondary vesicles (e.g. diencephalic; my/metencephalic. See http://www.dartmouth.edu/~rswenson/NeuroSci/chapter_4.html). Note that some sources may treat the term vesicle as the progenitor of the whole brain region; for example 'The retina develops directly from the neural tube as an outpouching from the diencephalic vesicle' synonym: "brain vesicle" RELATED [] synonym: "primitive brain vesicle" EXACT [] synonym: "early brain vesicle" EXACT [] synonym: "primary brain vesicle" NARROW [] synonym: "secondary brain vesicle" NARROW [] xref: SCTID:360409004 ! Primitive brain vesicle is_a: UBERON:0010064 {source="EHDAA2"} ! open anatomical space relationship: located_in UBERON:0006238 ! future brain relationship: part_of UBERON:0005281 {source="EHDAA2"} ! ventricular system of central nervous system relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0004753 name: scapulocoracoid def: "Skeletal element that consists of the scapula and the coracoid[VSAO, modified]." [VSAO:0005002, Wikipedia:Scapulocoracoid] comment: AO notes: ZFA defines as precursor to scapula and coracoid. Cartilage in TAO. Editor notes: todo - decide whether to create separate classes for cartilage & ossified. Wikipedia considers this absent in Therians, but if considered as a grouping of scapula and coracoid then it would be present synonym: "coraco-scapular cartilage" NARROW [ZFA:0001455] synonym: "scapulocoracoideum" EXACT [VSAO:0005002] xref: AAO:0000781 ! scapulocoracoid xref: ZFA:0001455 ! scapulocoracoid is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0007831 {source="VSAO"} ! pectoral girdle skeleton xref: TAO:0001455 ! scapulocoracoid cartilage xref: VSAO:0005002 ! scapulocoracoid property_value: external_definition "either a fusion of the scapula and coracoid (the two main bones of the shoulder girdle), or the scapula & coracoid considered as a single structural unit.[Palaeos]" xsd:string {date_retrieved="2012-09-10", source="http://palaeos.com/vertebrates/glossary/glossaryS.html"} property_value: external_definition "Fused, ossified portions of the scapula, procoracoid, and coracoid.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000781", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of scapular area (AAO:0000935)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000781", date_retrieved="2012-06-20"} property_value: external_definition "Pectoral fin cartilage that consists of a paired cartilaginous plate of the embryonic primary pectoral girdle and from which the scapular and coracaoid bones ossify.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001455", date_retrieved="2012-08-14", source="TAO:GA_TG", source="ZFIN:curator"} synonym: "scapulocoracoid cartilage" NARROW [TAO:0001455] synonym: "scapulo-coracoid cartilage" NARROW [TAO:0001455] [Term] id: UBERON:0006849 ! scapula name: scapula def: "Endochondral bone that is dorsoventrally compressed and provides attachment site for muscles of the pectoral appendage." [VSAO:0000157] comment: Usage notes: this class subsumes the scapula of teleosts and tetrapods - note we create a specific subclasses for pectoral limb scapula and pectoral fin scapula synonym: "scapulae" EXACT PLURAL [ZFA:0000583] synonym: "scapula bone" RELATED [BTO:0001218] xref: MESH:A02.835.232.087.783 ! scapula xref: VHOG:0001398 ! scapula (also: UBERON:0001124 'pectoral limb scapula') xref: VSAO:0000157 ! scapula is_a: UBERON:0002513 {source="TAO"} ! endochondral bone relationship: part_of UBERON:0007831 {source="ZFA-abduced"} ! pectoral girdle skeleton relationship: distally_connected_to UBERON:0007272 ! pectoral appendage skeleton property_value: has_relational_adjective "scapular" xsd:string [Term] id: UBERON:0010904 name: pectoral fin scapula def: "Endochondral bone that is located medial to the cleithrum, and articulates ventrally with the coracoid, medially with the mesocoracoid when the later is present and posteriorly with the upper one to three proximal radials. The scapula develops from the scapulocoracoid cartilage and belongs to the primary pectoral girdle. It may be perforated by the scapular foramen or it may be notched ventrally and forms together with a similar notch of the coracoid the scapulocoracoid foramen." [TAO:0000583] comment: Alternate definition: A scapula that is connected to a pectoral fin synonym: "teleost scapula" RELATED [] is_a: UBERON:0006849 ! scapula relationship: develops_from UBERON:0004753 {source="ZFA"} ! scapulocoracoid xref: TAO:0000583 ! scapula xref: ZFA:0000583 ! scapula synonym: "scapulas" RELATED PLURAL [TAO:0000583] synonym: "hypercoracocïde@fr" RELATED [TAO:0000583] synonym: "hypercoracocïdeum@fr" RELATED [TAO:0000583] synonym: "scapula@fr" RELATED [TAO:0000583] [Term] id: UBERON:0001124 name: pectoral limb scapula def: "In human anatomy, the scapula, omo (Medical Latin), or shoulder blade, is the bone that connects the humerus (arm bone) with the clavicle (collar bone). The scapula forms the posterior (back) located part of the shoulder girdle. In humans, it is a flat bone, roughly triangular in shape, placed on a posterolateral aspect of the thoracic cage. [WP,unvetted]." [Wikipedia:Scapula] comment: Alternate definition: A scapula that is connected to a pectoral limb. Taxon notes: present in all tetrapods with even vestiges of anterior limbs, e.g., turtles & birds & mammals. Development notes: chick scapula is of dual origin and segmentally organized[ISBN:978-0-12-319060-4] subset: uberon_slim synonym: "tetrapod scapula" RELATED [] synonym: "shoulder blade" EXACT [] xref: AAO:0000751 ! scapula xref: BTO:0001218 xref: FMA:13394 ! Scapula xref: GAID:186 ! scapula xref: VHOG:0001398 ! scapula (also: UBERON:0006849 'scapula') xref: MA:0001330 ! scapula xref: OpenCyc:Mx4rvVji0JwpEbGdrcN5Y29ycA xref: ncithesaurus:Scapula ! Scapula xref: EFO:0001400 ! scapula xref: galen:Scapula ! scapula xref: OpenCyc:Mx4rvVji0JwpEbGdrcN5Y29ycA ! shoulder blade xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/59/Pectoral_girdles-en.svg/200px-Pectoral_girdles-en.svg.png xref: EMAPA:18722 ! scapula xref: SCTID:302517007 ! Entire scapula is_a: UBERON:0006849 ! scapula relationship: part_of UBERON:0001467 {source="FMA"} ! shoulder relationship: develops_from UBERON:0006290 {evidence="definitional"} ! scapula cartilage condensation relationship: distally_connected_to UBERON:0000976 ! humerus xref: http://upload.wikimedia.org/wikipedia/commons/5/59/Pectoral_girdles-en.svg property_value: external_definition "Paired bony elements of endochondral origin. They are situated at the level of the jaw articulation, in a vertical position, with the suprascapular margin being dorsal and the glenoid end being ventral.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000751", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: has pars glenoidalis of scapula (AAO:0000753)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000751", date_retrieved="2012-06-20"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of scapular area (AAO:0000935)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000751", date_retrieved="2012-06-20"} xref: UMLS:C0036277 [Term] id: UBERON:0006290 name: scapula cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:18343 ! scapula cartilage condensation xref: EHDAA2:0001777 ! scapula cartilage condensation xref: VHOG:0001125 ! scapula cartilage condensation xref: EHDAA:8368 ! scapula cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0006291 {source="EHDAA2"} ! scapula pre-cartilage condensation relationship: part_of UBERON:0007831 {source="EHDAA2"} ! pectoral girdle skeleton relationship: part_of UBERON:0000922 ! embryo relationship: develops_into UBERON:0006849 ! scapula [Term] id: UBERON:0006291 ! scapula pre-cartilage condensation name: scapula pre-cartilage condensation comment: Development notes: the scapula has been shown to develop from multiple tissues, such as the dermomyotome of the somites, the mesodermal portion of the soma- topleure (a domain of the lateral plate mesoderm or LPM) and neural crest cell-derived mesenchyme (Huang et al., 2000; Matsuoka et al., 2005; Wang et al., 2005).[PMID:21455939] subset: emapa_ehdaa2 xref: EMAPA:18027 ! scapula pre-cartilage condensation xref: EHDAA2:0001778 ! scapula pre-cartilage condensation xref: VHOG:0000960 ! scapula pre-cartilage condensation xref: EHDAA:6041 ! scapula pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme relationship: part_of UBERON:0007831 {source="EHDAA2"} ! pectoral girdle skeleton relationship: part_of UBERON:0000922 ! embryo relationship: develops_into UBERON:0006849 ! scapula [Term] id: UBERON:0006292 name: shoulder joint primordium comment: Note that this is part of the forelimb skeleton in EHDAA2, but this violates part-disjointness subset: emapa_ehdaa2 xref: EMAPA:17712 ! shoulder joint primordium xref: EHDAA2:0001836 ! shoulder joint primordium xref: EHDAA:8493 ! shoulder joint primordium is_a: UBERON:0005856 {source="EHDAA2"} ! mesenchymal condensation relationship: develops_from UBERON:0003322 {source="EHDAA2"} ! mesenchyme of shoulder relationship: part_of UBERON:0003322 ! mesenchyme of shoulder relationship: develops_into UBERON:0001470 ! glenohumeral joint [Term] id: UBERON:0006295 ! sternebral bone pre-cartilage condensation name: sternebral bone pre-cartilage condensation subset: emapa_ehdaa2 xref: EMAPA:18345 ! sternebral bone pre-cartilage condensation xref: EHDAA2:0001912 ! sternebral bone pre-cartilage condensation xref: VHOG:0000961 ! sternebral bone pre-cartilage condensation xref: EHDAA:9565 ! sternebral bone pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme relationship: part_of UBERON:0000975 ! sternum [Term] id: UBERON:0006297 ! sublingual gland primordium name: sublingual gland primordium subset: emapa_ehdaa2 xref: EMAPA:17752 ! sublingual gland primordium xref: EHDAA2:0001935 ! sublingual gland primordium xref: EHDAA:7989 ! sublingual gland primordium is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001044 ! salivary gland relationship: develops_into UBERON:0001832 ! sublingual gland [Term] id: UBERON:0006298 name: submandibular gland primordium subset: emapa_ehdaa2 xref: EMAPA:17755 ! submandibular gland primordium xref: EHDAA2:0001939 ! submandibular gland primordium xref: EHDAA:9255 ! submandibular gland primordium is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001044 ! salivary gland relationship: develops_into UBERON:0001736 ! submandibular gland [Term] id: UBERON:0006300 ! supracardinal vein name: supracardinal vein def: "Either of two veins in the mammalian embryo and various adult lower vertebrate forms located in the thoracic and abdominal regions dorsolateral to and on either side of the descending aorta and giving rise to the azygos and hemiazygos veins and a part of the inferior vena cava[MW]. These veins drain the body wall via the segmental intercostal veins, thus taking over the function of the posterior cardinals[ISBN]" [http://www.merriam-webster.com/medical/supracardinal%20vein, ISBN-10:0443065837 "Human embryology\, Larsen"] subset: emapa_ehdaa2 xref: EMAPA:16830 ! supracardinal vein xref: EHDAA2:0001964 ! supracardinal vein xref: EHDAA:7492 ! supracardinal vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004581 ! systemic venous system xref: ncithesaurus:Supracardinal_Vein ! Supracardinal Vein xref: SCTID:308829001 ! Entire supracardinal vein xref: UMLS:C0231090 [Term] id: UBERON:0008267 name: left supracardinal vein def: "The left thoracic supracardinal vein loses its connection with the left posterior cardinal veins and left sinus horn and subsequently drains into the right supracardinal system." [ISBN-10:0443065837 "Human embryology\, Larsen"] is_a: UBERON:0006300 ! supracardinal vein xref: SCTID:361449001 ! Left supracardinal vein [Term] id: UBERON:0008268 ! right supracardinal vein name: right supracardinal vein def: "The right supracardinal vein loses its connection with the posterior cardinal vein and makes a new anastomosis with the segments of the superior vena cava derived from the anterior cardinal vein, becoming the azygos vein." [ISBN-10:0443065837 "Human embryology\, Larsen"] is_a: UBERON:0006300 ! supracardinal vein xref: SCTID:361450001 ! Right supracardinal vein xref: EHDAA2:0004539 ! supracardinal vein right [Term] id: UBERON:0006303 name: tracheal diverticulum subset: emapa_ehdaa2 xref: EMAPA:16740 ! tracheal diverticulum xref: RETIRED_EHDAA2:0002072 ! tracheal diverticulum is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0006304 name: trigeminal V preganglion subset: emapa_ehdaa2 xref: EMAPA:16663 ! trigeminal V preganglion xref: RETIRED_EHDAA2:0002089 ! trigeminal V preganglion xref: EHDAA:924 ! trigeminal V preganglion is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001714 ! cranial ganglion [Term] id: UBERON:0009195 name: anal membrane comment: During the 7th week the urorectal septum divides the cloacal membrane into a urogenital membrane (ventrally) and an anal membrane (dorsally) [http://www.embryology.ch/anglais/ugenital/genitexterne01.html] is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0006217 {source="EHDAA2"} ! cloacal membrane relationship: part_of UBERON:0001353 {source="EHDAA2"} ! anal region xref: ncithesaurus:Anal_Membrane ! Anal Membrane xref: EHDAA2:0004018 ! anal membrane xref: SCTID:344130000 ! Entire anal membrane xref: UMLS:C1288337 [Term] id: UBERON:0006307 name: urogenital membrane subset: emapa_ehdaa2 comment: During the 7th week the urorectal septum divides the cloacal membrane into a urogenital membrane (ventrally) and an anal membrane (dorsally) [http://www.embryology.ch/anglais/ugenital/genitexterne01.html] xref: EMAPA:17210 ! urogenital membrane of genitourinary system xref: EMAPA:17378 ! urogenital membrane of urinary system xref: RETIRED_EHDAA2:0002141 ! urogenital membrane xref: VHOG:0001187 ! urogenital membrane xref: EHDAA:7011 ! urogenital membrane is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0006217 {source="EHDAA2"} ! cloacal membrane relationship: part_of UBERON:0001008 {source="EHDAA2"} ! excretory system relationship: part_of UBERON:0004122 ! genitourinary system xref: EHDAA2:0004025 ! urogenital membrane xref: SCTID:172994001 ! Urogenital membrane property_value: external_definition "Ventral part of the cloacal membrane separating the gut from the fetus external environment. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001187", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/urogenital+membrane", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006308 name: vagal X nerve trunk subset: emapa_ehdaa2 xref: EMAPA:17272 ! vagal X nerve trunk xref: EHDAA2:0002160 ! vagal X nerve trunk xref: VHOG:0000736 ! vagal X nerve trunk xref: EHDAA:4659 ! vagal X nerve trunk is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0002464 ! nerve trunk relationship: part_of UBERON:0004293 ! parasympathetic nerve [Term] id: UBERON:0006309 name: venous vitelline plexus subset: emapa_ehdaa2 xref: EMAPA:17020 ! vitelline venous plexus (also: UBERON:0006310 'vitelline venous plexus') xref: RETIRED_EHDAA2:0002172 ! venous vitelline plexus xref: EHDAA:1945 ! venous vitelline plexus (also: UBERON:0006310 'vitelline venous plexus') is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004581 ! systemic venous system relationship: part_of UBERON:0004582 ! venous system [Term] id: UBERON:0006310 name: vitelline venous plexus subset: emapa_ehdaa2 xref: EMAPA:17020 ! vitelline venous plexus (also: UBERON:0006309 'venous vitelline plexus') xref: EHDAA2:0002210 ! vitelline venous plexus xref: EHDAA:1945 ! venous vitelline plexus (also: UBERON:0006309 'venous vitelline plexus') is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004581 ! systemic venous system relationship: part_of UBERON:0004582 ! venous system [Term] id: UBERON:0006319 name: spinal cord reticular nucleus synonym: "spinal reticular nucleus" EXACT [FMA:73909] xref: FMA:73909 ! Spinal reticular nucleus xref: MA:0001123 ! spinal cord reticular nucleus is_a: UBERON:0000125 ! neural nucleus is_a: UBERON:0002020 ! gray matter of neuraxis relationship: part_of UBERON:0002256 ! dorsal horn of spinal cord [Term] id: UBERON:0006531 name: oculomotor muscle def: "The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris." [MESH:A02.633.567.700] comment: we follow MA in making this a subckass of extra-ocular muscle but the distinction is not clear xref: MA:0002432 ! oculomotor muscle xref: MESH:A02.633.567.700 ! oculomotor muscle is_a: UBERON:0001601 {source="MA"} ! extra-ocular muscle xref: ncithesaurus:Oculomotor_Muscle ! Oculomotor Muscle xref: UMLS:C0028863 [Term] id: UBERON:0006532 ! oblique extraocular muscle name: oblique extraocular muscle xref: MA:0001275 ! oblique extraocular muscle is_a: UBERON:0006531 ! oculomotor muscle [Term] id: UBERON:0006533 ! rectus extraocular muscle name: rectus extraocular muscle xref: MA:0001278 ! rectus extraocular muscle is_a: UBERON:0006531 ! oculomotor muscle [Term] id: UBERON:0006320 name: inferior oblique extraocular muscle subset: vertebrate_core def: "thin, narrow muscle placed near the anterior margin of the floor of the orbit." [Wikipedia:Inferior_oblique_muscle] comment: Taxon notes (via VHOG): "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution." Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective, Third Edition (2001) Orlando Fla.: Harcourt College Publishers, p.331 synonym: "musculus obliquus inferior bulbi" EXACT [Wikipedia:Inferior_oblique_muscle] synonym: "obliquus oculi inferior" EXACT [Wikipedia:Inferior_oblique_muscle] synonym: "obliquus inferior" EXACT [FMA:49040] synonym: "inferior oblique" EXACT [FMA:49040] synonym: "inferior oblique muscle" EXACT [] xref: FMA:49040 ! Inferior oblique xref: MA:0001276 ! inferior oblique extraocular muscle xref: ZFA:0000861 ! ventral oblique extraocular muscle xref: VHOG:0001132 ! ventral oblique extraocular muscle is_a: UBERON:0006532 {source="MA"} ! oblique extraocular muscle xref: SCTID:181156006 ! Entire inferior oblique xref: ncithesaurus:Inferior_Oblique_Muscle ! Inferior Oblique Muscle xref: TAO:0000861 ! ventral oblique extraocular muscle relationship: innervated_by UBERON:0001643 {source="dbpedia"} ! oculomotor nerve synonym: "musculus obliquus inferior bulbi" RELATED LATIN [Wikipedia:Inferior_oblique_muscle] relationship: has_muscle_insertion UBERON:0001603 {source="dbpedia", notes="laterally onto the eyeball deep to the lateral rectus by a short flat tendon"} ! lateral rectus extra-ocular muscle relationship: has_muscle_origin UBERON:0002397 {source="dbpedia", notes="orbital surface of the maxilla lateral to the lacrimal groove"} ! maxilla xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Eyemuscles.png synonym: "ventral oblique extraocular muscle" EXACT [VHOG:0001132] synonym: "ventral oblique extraocular muscles" RELATED [VHOG:0001132] property_value: homology_notes "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0001132", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.331", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0582817 [Term] id: UBERON:0006321 name: superior oblique extraocular muscle def: "The superior oblique muscle, or obliquus oculi superior, is a fusiform muscle in the upper, medial side of the orbit whose primary action is downward, lateral rotation of the eye. One of the extraocular muscles, the superior oblique is the only muscle innervated by the trochlear nerve (the fourth cranial nerve)." [Wikipedia:Superior_oblique_muscle] subset: vertebrate_core synonym: "obliquus superior" EXACT [FMA:49039] synonym: "superior oblique" EXACT [FMA:49039] synonym: "superior oblique muscle" EXACT [] synonym: "musculus obliquus superior" EXACT [AAO:0010119] synonym: "obliquus oculi superior" RELATED [Wikipedia:Superior_oblique_muscle] synonym: "M. obliquus superior" RELATED [Wikipedia:Superior_oblique_muscle] xref: FMA:49039 ! Superior oblique xref: MA:0001277 ! superior oblique extraocular muscle xref: ZFA:0000738 ! dorsal oblique extraocular muscle xref: AAO:0010119 ! musculus obliquus superior xref: VHOG:0001131 ! dorsal oblique extraocular muscle is_a: UBERON:0006532 {source="MA"} ! oblique extraocular muscle xref: SCTID:181155005 ! Entire superior oblique xref: ncithesaurus:Superior_Oblique_Muscle ! Superior Oblique Muscle xref: TAO:0000738 ! dorsal oblique extraocular muscle relationship: innervated_by UBERON:0001644 {source="dbpedia"} ! trochlear nerve synonym: "musculus obliquus superior bulbi" RELATED LATIN [Wikipedia:Superior_oblique_muscle] relationship: has_muscle_insertion UBERON:0010230 {source="dbpedia", notes="Outer posterior quadrant of the eyeball"} ! eyeball of camera-type eye xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Eyemuscles.png property_value: external_definition "Cranial nerve IV innervated; dorsal in the obliquus group.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010119", date_retrieved="2012-06-20", source="AAO:EJS"} synonym: "dorsal oblique extraocular muscle" EXACT [VHOG:0001131] synonym: "dorsal oblique extraocular muscles" RELATED [VHOG:0001131] property_value: homology_notes "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0001131", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.331", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0582816 [Term] id: UBERON:0006322 name: inferior rectus extraocular muscle def: "a muscle in the orbit that depresses, adducts, and helps extort (rotate laterally) the eye. The inferior rectus muscle is the only muscle that is capable of depressing the pupil when it is in a fully abducted position." [Wikipedia:Inferior_rectus_muscle] subset: vertebrate_core synonym: "inferior rectus" EXACT [FMA:49036] synonym: "inferior rectus muscle" EXACT [] xref: FMA:49036 ! Inferior rectus xref: MA:0001279 ! inferior rectus extraocular muscle xref: ZFA:0000457 ! ventral rectus xref: VHOG:0001130 ! ventral rectus extraocular muscle is_a: UBERON:0006533 {source="MA"} ! rectus extraocular muscle xref: SCTID:181154009 ! Entire inferior rectus xref: ncithesaurus:Inferior_Rectus_Muscle ! Inferior Rectus Muscle xref: TAO:0000457 ! ventral rectus synonym: "musculus rectus inferior bulbi" RELATED LATIN [Wikipedia:Inferior_rectus_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Eyemuscles.png synonym: "ventral rectus extraocular muscle" EXACT [VHOG:0001130] synonym: "ventral rectus" RELATED [TAO:0000457] synonym: "ventral recti" RELATED PLURAL [TAO:0000457] property_value: homology_notes "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0001130", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.331", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0582819 [Term] id: UBERON:0006323 def: "The superior rectus muscle is a muscle in the orbit. It is one of the extraocular muscles. It is innervated by the superior division of the oculomotor nerve (Cranial Nerve III). In the primary position (looking straight ahead), the superior rectus muscle's primary function is elevation, although it also contributes to intorsion and adduction." [Wikipedia:Superior_rectus_muscle] name: superior rectus extraocular muscle subset: vertebrate_core synonym: "superior rectus" EXACT [FMA:49035] synonym: "superior rectus muscle" EXACT [] xref: FMA:49035 ! Superior rectus xref: MA:0001282 ! superior rectus extraocular muscle xref: ZFA:0000345 ! dorsal rectus xref: VHOG:0001128 ! dorsal rectus extraocular muscle is_a: UBERON:0006533 {source="MA"} ! rectus extraocular muscle xref: SCTID:181153003 ! Entire superior rectus xref: ncithesaurus:Superior_Rectus_Muscle ! Superior Rectus Muscle xref: TAO:0000345 ! dorsal rectus relationship: innervated_by UBERON:0001643 {source="dbpedia"} ! oculomotor nerve synonym: "musculus rectus superior bulbi" RELATED LATIN [Wikipedia:Superior_rectus_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Eyemuscles.png synonym: "dorsal rectus extraocular muscle" EXACT [VHOG:0001128] synonym: "dorsal rectus" RELATED [TAO:0000345] property_value: homology_notes "The ability to rotate the eyeball is common to all vertebrates with well-developed eyes, regardless of the habitat in which they live, so these [extrinsic ocular] muscles tend to be conservative. They change little during the course of evolution.[well established][VHOG]" xsd:string {external_class="VHOG:0001128", ontology="VHOG", source="ISBN:978-0030223693 Liem KF\, Bemis WE\, Walker WF\, Grande L\, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.331", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0582818 [Term] id: UBERON:0006326 name: base of arytenoid synonym: "arytenoid cartilage base" EXACT [FMA:55349] synonym: "base of arytenoid" EXACT [FMA:55349] synonym: "base of arytenoid cartilage" EXACT [FMA:55349] xref: FMA:55349 ! Base of arytenoid cartilage xref: MA:0001761 ! base of arytenoid is_a: UBERON:0001994 ! hyaline cartilage is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001740 ! arytenoid cartilage xref: SCTID:279532006 ! Entire base of arytenoid cartilage [Term] id: UBERON:0006327 name: laryngeal extrinsic muscle synonym: "extrinsic muscle of larynx" EXACT [FMA:55225] xref: FMA:55225 ! Extrinsic muscle of larynx xref: MA:0001769 ! laryngeal extrinsic muscle is_a: UBERON:0001568 ! muscle of larynx xref: SCTID:244808004 ! Extrinsic muscle of larynx [Term] id: UBERON:0006328 name: laryngeal intrinsic muscle synonym: "intrinsic muscle of larynx" EXACT [FMA:55226] synonym: "intrinsic laryngeal muscle" EXACT [FEED:FEED] synonym: "intrinsic laryneal muscles" RELATED [FEED:FEED] xref: FMA:55226 ! Intrinsic muscle of larynx xref: MA:0001770 ! laryngeal intrinsic muscle is_a: UBERON:0001568 ! muscle of larynx xref: SCTID:244810002 ! Entire intrinsic laryngeal muscle property_value: external_definition "each muscle listed separately.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} [Term] id: UBERON:0006330 name: anterior lingual gland def: "Anterior lingual glands (also called apical glands) are deeply placed seromucous glands that are located near the tip of the tongue on each side of the frenulum linguae. They are found on the under surface of the apex of the tongue, and are covered by a bundle of muscular fibers derived from the Styloglossus and Longitudinalis inferior." [Wikipedia:Anterior_lingual_glands] synonym: "Bauhin's glands:" EXACT [Wikipedia:Anterior_lingual_glands] synonym: "Blandin's glands:" EXACT [Wikipedia:Anterior_lingual_glands] synonym: "Nuhn's glands:" EXACT [Wikipedia:Anterior_lingual_glands] synonym: "anterior lingual salivary gland" EXACT [FMA:59796] synonym: "lingual salivary gland" EXACT [FMA:59796] xref: FMA:59796 ! Lingual salivary gland xref: MA:0002701 ! anterior lingual gland is_a: UBERON:0001830 ! minor salivary gland relationship: part_of UBERON:0000165 ! mouth xref: ncithesaurus:Lingual_Salivary_Gland ! Lingual Salivary Gland xref: SCTID:362179003 ! Entire anterior lingual gland xref: UMLS:C0930558 [Term] id: UBERON:0006333 name: snout def: "." [Wikipedia:Snout] subset: vertebrate_core synonym: "muzzle" RELATED [MA:0001910] xref: ZFA:0005496 ! snout xref: MA:0001910 ! snout (also: UBERON:0004089 'midface') is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0001456 ! face xref: SCTID:41127006 ! Muzzle xref: TAO:0001712 ! snout property_value: external_definition "Surface structure that is the region of the head in front of and between the orbits, and above the lower jaw. Nares are located on the snout[ZFA]." xsd:string {ontology="ZFA", ontology_class="ZFA:0005496", date_retrieved="2012-10-05"} [Term] id: UBERON:0012128 name: nose tip synonym: "apex nasi" EXACT [FMA:TA] synonym: "apex of nose" EXACT [FMA:59518] synonym: "nasal tip" EXACT [FMA:59518] synonym: "tip of nose" EXACT [FMA:59518] synonym: "tip of snout" RELATED [] synonym: "snout tip" RELATED [] is_a: UBERON:0006983 ! anatomical point relationship: part_of UBERON:0007827 {source="FMA"} ! external nose xref: FMA:59518 ! tip of nose xref: SCTID:361926005 ! Entire apex of nose [Term] id: UBERON:0006334 name: posterior lateral line def: "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)" [ZFA:0000944] comment: check XAO/AAO subset: dubious_grouping synonym: "pll" EXACT [ZFA:0000944] xref: XAO:0000465 ! caudal lateral line xref: ZFA:0000944 ! posterior lateral line xref: EFO:0003595 ! posterior lateral line is_a: UBERON:0010202 ! lateral line xref: AAO:0011024 ! caudal lateral line xref: TAO:0000944 ! posterior lateral line property_value: external_definition "One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. (See Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000944", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from posterior lateral line primordium (TAO:0001157)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000944", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of posterior lateral line system (TAO:0001471)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000944", date_retrieved="2012-08-14"} [Term] id: UBERON:0006336 name: obsolete unspecified consider: XAO:0003003 ! unspecified consider: ZFA:0001093 ! unspecified is_obsolete: true [Term] id: UBERON:0006338 name: lateral ventricle choroid plexus stroma comment: editors note: definitions should be fixed to use generic stroma class xref: MA:0000963 intersection_of: UBERON:0005206 ! choroid plexus stroma intersection_of: part_of UBERON:0002285 ! telencephalic ventricle relationship: part_of UBERON:0002307 ! choroid plexus of lateral ventricle def: "A choroid plexus stroma that is part of a lateral ventricle." [OBOL:automatic] [Term] id: UBERON:0006339 name: third ventricle choroid plexus stroma xref: MA:0000881 intersection_of: UBERON:0005206 ! choroid plexus stroma intersection_of: part_of UBERON:0002286 ! third ventricle relationship: part_of UBERON:0002288 ! choroid plexus of third ventricle def: "A choroid plexus stroma that is part of a third ventricle." [OBOL:automatic] [Term] id: UBERON:0006340 name: fourth ventricle choroid plexus stroma xref: MA:0000985 intersection_of: UBERON:0005206 ! choroid plexus stroma intersection_of: part_of UBERON:0002422 ! fourth ventricle relationship: part_of UBERON:0002290 ! choroid plexus of fourth ventricle def: "A choroid plexus stroma that is part of a fourth ventricle." [OBOL:automatic] [Term] id: UBERON:0006341 name: outer renal medulla peritubular capillary xref: MA:0002589 intersection_of: UBERON:0005272 ! peritubular capillary intersection_of: part_of UBERON:0001293 ! outer medulla of kidney synonym: "kidney outer medulla peritubular capillary" EXACT [MA:0002589] def: "A peritubular capillary that is part of a outer medulla of kidney." [OBOL:automatic] [Term] id: UBERON:0012441 name: endothelium of peritubular capillary synonym: "peritubular capillary endothelium" EXACT [] synonym: "peritubular endothelium" BROAD [] intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0005272 ! peritubular capillary [Term] id: UBERON:0006442 name: subhepatic recess synonym: "hepatic recess" EXACT [] synonym: "subhepatic space" EXACT [FMA:20676] is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001179 {source="MA-abduced"} ! peritoneal cavity xref: SCTID:36051002 ! subhepatic recess xref: FMA:20676 ! subhepatic space [Term] id: UBERON:0006342 name: left subhepatic recess comment: Compare with lesser sac / omental bursa and its cavities / recesses synonym: "left hepatic recess" EXACT [MA:0000444] xref: MA:0000444 ! left hepatic recess xref: EMAPA:18047 ! left hepatic recess xref: FMA:20677 ! left subhepatic space is_a: UBERON:0006442 ! hepatic recess relationship: part_of UBERON:0005252 {notes="unverified"} ! omental bursa cavity [Term] id: UBERON:0006343 name: right subhepatic recess def: "The hepatorenal recess or subhepatic recess is the space that separates the liver from the right kidney. As a potential space, the recess is not filled with fluid under normal conditions. However, fluid can collect in this space in circumstances where the abdomen fills with fluid, such as hemoperitoneum. This fluid may be seen on ultrasound or computed tomography (CT scan)." [Wikipedia:Hepatorenal_recess_of_subhepatic_space] synonym: "hepatorenal recess" RELATED [Wikipedia:Hepatorenal_recess_of_subhepatic_space] synonym: "Morison pouch" RELATED [Wikipedia:Hepatorenal_recess_of_subhepatic_space] synonym: "Morison's pouch" RELATED [Wikipedia:Hepatorenal_recess_of_subhepatic_space] synonym: "pouch of Morison" RELATED [Wikipedia:Hepatorenal_recess_of_subhepatic_space] synonym: "pouch of Morrison" RELATED [Wikipedia:Hepatorenal_recess_of_subhepatic_space] synonym: "hepatorenal fossa" EXACT [FMA:14715] synonym: "hepatorenal recess of subhepatic space" EXACT [FMA:14715] synonym: "Morison's pouch" EXACT [FMA:14715] synonym: "recessus hepatorenalis" EXACT [FMA:14715] synonym: "recessus hepatorenalis recessi subhepatici" EXACT LATIN [FMA:TA] synonym: "right posterior subphrenic space" EXACT [FMA:14715] synonym: "right subhepatic space" EXACT [FMA:14715] synonym: "right hepatic recess" EXACT [MA:0000450] xref: MA:0000450 ! right hepatic recess xref: EMAPA:18050 ! right hepatic recess xref: FMA:14715 ! hepatorenal recess is_a: UBERON:0006442 ! hepatic recess [Term] id: UBERON:0006349 name: epigastric artery xref: MA:0001948 ! epigastric artery xref: EMAPA:18750 ! epigastric artery xref: MESH:A07.231.114.330 ! epigastric artery is_a: UBERON:0001637 ! artery xref: ncithesaurus:Epigastric_Artery ! Epigastric Artery xref: SCTID:261400009 ! Epigastric artery xref: UMLS:C0282640 [Term] id: UBERON:0006443 ! prinicipal vein of limb name: prinicipal vein of limb is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0002101 ! limb [Term] id: UBERON:0006351 name: principal vein of forelimb xref: MA:0002199 ! principal vein of forelimb xref: EMAPA:17018 ! principal vein of forelimb intersection_of: UBERON:0006443 ! prinicipal vein of limb intersection_of: part_of UBERON:0002102 ! forelimb def: "A prinicipal vein of limb that is part of a forelimb." [OBOL:automatic] [Term] id: UBERON:0006353 name: principal vein of hindlimb xref: MA:0002200 ! principal vein of hindlimb xref: EMAPA:17019 ! principal vein of hindlimb intersection_of: UBERON:0006443 ! prinicipal vein of limb intersection_of: part_of UBERON:0002103 ! hindlimb def: "A prinicipal vein of limb that is part of a hindlimb." [OBOL:automatic] [Term] id: UBERON:0006355 name: superior vesical vein xref: MA:0002227 ! superior vesical vein xref: EMAPA:18646 ! superior vesical vein is_a: UBERON:0002460 ! vesical vein [Term] id: UBERON:0006356 name: epigastric vein xref: MA:0002114 ! epigastric vein xref: EMAPA:18759 ! epigastric vein is_a: UBERON:0001638 ! vein xref: ncithesaurus:Epigastric_Vein ! Epigastric Vein xref: UMLS:C1707930 [Term] id: UBERON:0006359 name: mesoduodenum xref: MA:0001556 ! mesoduodenum xref: EMAPA:17198 ! mesoduodenum of mesentery of caudal part of duodenum of midgut xref: EMAPA:17183 ! mesoduodenum of mesentery of rostral part of duodenum of foregut xref: EMAPA:19082 ! mesoduodenum of mesentery of duodenum of gut is_a: UBERON:0001170 ! mesentery of small intestine [Term] id: UBERON:0006360 name: intermolar eminence xref: MA:0001590 ! intermolar eminence xref: EMAPA:18273 ! intermolar eminence of tongue of pharynx of foregut xref: EMAPA:18876 ! intermolar eminence of tongue of pharynx of gut is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0006374 name: part of afferent arteriole forming the juxtaglomerular complex synonym: "renin-producing cells" RELATED [MA:0002580] xref: MA:0002580 ! part of afferent arteriole forming juxtaglomerular complex xref: EMAPA:28269 ! part of afferent arteriole forming the juxtaglomerular complex is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002303 ! juxtaglomerular apparatus relationship: part_of UBERON:0004639 ! afferent arteriole synonym: "part of afferent arteriole forming juxtaglomerular complex" EXACT [MA:0002580] [Term] id: UBERON:0011933 ! vibrissa unit name: vibrissa unit comment: MA has distinct classes for vibrissa and vibrissa hair - the former includes the follicle and is thus not the hair proper. We model this as the 'vibrissa unit' synonym: "vibrissa" RELATED [MA:0000163] is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: part_of UBERON:0002416 {source="MA"} ! integumental system xref: MA:0000163 ! vibrissa [Term] id: UBERON:0006378 name: vibrissa hair def: "A specialized hair usually employed for tactile sensation. Vibrissae hair grow around the nostrils, above the lips, and on other parts of the face of most mammals, and all primates except humans. vibrissae are different from other hairs because they are implanted in a special hair follicle incorporating a capsule of blood called a blood sinus and heavily innervated by sensory nerves[WP]." [Wikipedia:Whiskers, https://sourceforge.net/tracker/?func=detail&aid=3213510&group_id=76834&atid=1205376] synonym: "macrovibrissa" NARROW [] synonym: "microvibrissa" NARROW [] synonym: "motile vibrissa" NARROW [] synonym: "true whisker" NARROW [] synonym: "whisker" NARROW [MA:0000163] synonym: "vibrissa hair" EXACT [] synonym: "vibrissae" RELATED PLURAL [] synonym: "sinus hair" EXACT [EMAPA:26747, MP:0009003] synonym: "touch hair" EXACT [MP:0009003] synonym: "contour hair" EXACT [MP:0009003] xref: MA:0000782 ! vibrissa hair xref: EMAPA:17529 ! vibrissa xref: EMAPA:26747 ! sinus hair xref: BTO:0003488 ! vibrissa xref: MESH:A13.950 ! vibrissae xref: http://eulep.pdn.cam.ac.uk/~skinbase/Annotated_anatomy_of_the_mouse_vibrissa/vibrissa_labelled.jpg is_a: UBERON:0001037 ! strand of hair relationship: part_of UBERON:0011933 {source="MA"} ! vibrissa unit relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: dubious_for_taxon NCBITaxon:9606 {source="Skinbase"} ! Homo sapiens property_value: taxon_notes "In harbor seals, the structure of the vibrissal shaft is undulated (wavy) and flattened. This specialization is also found in most true seals. In contrast, the whiskers of the California sea lion are circular or elliptical in cross-section and are smooth." xsd:string {source="http://en.wikipedia.org/wiki/Hydrodynamic_reception#Species_differences_in_vibrissae"} [Term] id: UBERON:0011931 name: nasal hair def: "Hair in the nose" [Wikipedia:Nasal_hair] synonym: "hair of vestibular part of nose" EXACT [FMA:53670] synonym: "nose hair" EXACT [FMA:53670] intersection_of: UBERON:0001037 ! strand of hair intersection_of: part_of UBERON:0000004 ! olfactory apparatus xref: FMA:53670 ! hair of nose xref: SCTID:368885003 ! Entire intranasal hair synonym: "hair of nose" EXACT [FMA:53670] disjoint_from: UBERON:0006378 ! vibrissa [Term] id: UBERON:0006428 name: basisphenoid bone comment: "Endochondral ossification of the ventromedial portion of the braincase." [AAO:0000040] // "An endochondral bone that is located ventral to the pterosphenoid and dorsal to the parasphenoid. Basisphenoid is a median bone that is usually Y-shaped." [TAO:0000169] synonym: "basisphenoid" EXACT [AAO:0000040] xref: MA:0001463 ! basisphenoid bone xref: EMAPA:18706 ! basisphenoid bone xref: AAO:0000040 ! basisphenoid is_a: UBERON:0011164 {source="MA"} ! neurocranium bone relationship: part_of UBERON:0001677 ! sphenoid bone relationship: part_of UBERON:0002241 ! chondrocranium relationship: develops_from UBERON:0009194 {source="cjm"} ! basisphenoid cartilage condenstion xref: SCTID:95945003 ! Entire basisphenoid bone xref: TAO:0000169 ! basisphenoid property_value: external_definition "Endochondral ossification of the ventromedial portion of the braincase.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000040", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000040", date_retrieved="2012-06-20"} property_value: external_definition "An endochondral bone that is located ventral to the pterosphenoid and dorsal to the parasphenoid. Basisphenoid is a median bone that is usually Y-shaped.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000169", date_retrieved="2012-08-14", source="TAO:wd"} synonym: "basisphcénocïde@fr" RELATED [TAO:0000169] synonym: "propituital@fr" RELATED [TAO:0000169] [Term] id: UBERON:0006831 name: pre-tracheal muscle xref: MA:0001798 ! pretracheal muscle synonym: "pretracheal muscle" EXACT [MA:0001798] xref: EMAPA:25142 ! pre-tracheal muscle is_a: UBERON:0000933 ! pharyngeal muscle [Term] id: UBERON:0007719 name: bone of reproductive structure def: "A bone that is part of a reproductive structure." [OBOL:automatic] synonym: "baculum" NARROW [] synonym: "os penis/os clitoris" RELATED [] intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0005156 ! reproductive structure relationship: never_in_taxon NCBITaxon:9606 {source="Wikipedia"} ! Homo sapiens [Term] id: UBERON:0006440 name: os clitoris def: "A bone that is part of a clitoris." [OBOL:automatic] synonym: "baubellum" EXACT [Wikipedia:Baculum] synonym: "os clitoridis" EXACT [Wikipedia:Baculum] xref: MA:0000387 ! os clitoris xref: EMAPA:30823 ! os clitoris is_a: UBERON:0007719 ! penis/os clitoris intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002411 ! clitoris relationship: never_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: sexually_homologous_to UBERON:0006435 ! os penis [Term] id: UBERON:0006435 name: os penis def: "a bone found in the penis of most mammals. It is absent in humans, but present in other primates, such as the closely-related chimpanzee. The bone aids in sexual intercourse[WP]." [Wikipedia:Baculum] comment: Taxon notes: found in most mammals, with the exception of humans synonym: "baculum" EXACT [Wikipedia:Baculum] synonym: "penile bone" EXACT [Wikipedia:Baculum] synonym: "penis bone" EXACT [Wikipedia:Baculum] xref: MA:0000406 ! os penis xref: EMAPA:29769 ! os penis xref: SCTID:27962002 ! Baculum is_a: UBERON:0007719 ! penis/os clitoris intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000989 ! penis relationship: never_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia [Term] id: UBERON:0006445 name: caudal middle frontal gyrus def: "Component of the middle frontal gyrus. The rostral boundary of the middle frontal gyrus was the rostral extent of the middle frontal gyrus whereas the caudal boundary was the precentral gyrus. The medial and lateral boundaries were designated as the superior frontal sulcus and the inferior frontal sulcus respectively (Christine Fennema-Notestine)." [NIF_GrossAnatomy:birnlex_1083] synonym: "caudal middle frontal gyrus" EXACT [NIF_GrossAnatomy:birnlex_1083] synonym: "posterior part of middle frontal gyrus" EXACT [FMA:70688] xref: FMA:70688 ! posterior part of middle frontal gyrus xref: NIF_GrossAnatomy:birnlex_1083 ! Caudal middle frontal gyrus is_a: UBERON:0002791 ! regional part of telencephalon is_a: UBERON:0003022 ! lobe parts of cerebral cortex relationship: part_of UBERON:0002702 ! middle frontal gyrus [Term] id: UBERON:0006446 name: rostral middle frontal gyrus def: "Component of the middle frontal gyrus The rostral boundary is the first appearance of the superior frontal sulcus whereas the caudal boundary is the middle frontal gyrus. The medial and lateral boundaries are the superior frontal sulcus and the inferior frontal sulcus respectively (Christine Fennema-Notestine)." [NIF_GrossAnatomy:birnlex_1090] synonym: "rostral middle frontal gyrus" EXACT [NIF_GrossAnatomy:birnlex_1090] synonym: "anterior part of middle frontal gyrus" EXACT [FMA:70687] xref: FMA:70687 ! anterior part of middle frontal gyrus xref: NIF_GrossAnatomy:birnlex_1090 ! Rostral middle frontal gyrus is_a: UBERON:0002791 ! regional part of telencephalon is_a: UBERON:0003022 ! lobe parts of cerebral cortex relationship: part_of UBERON:0002702 ! middle frontal gyrus [Term] id: UBERON:0006448 name: first lumbar spinal cord segment subset: defined_by_ordinal_series synonym: "L1 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1336] synonym: "first lumbar spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1336] synonym: "L1 segment" EXACT [FMA:71187] xref: FMA:71187 ! l1 segment xref: NIF_GrossAnatomy:birnlex_1336 ! First lumbar spinal cord segment is_a: UBERON:0007716 ! lumbar subsegment of spinal cord xref: SCTID:278776009 ! First lumbar spinal cord segment [Term] id: UBERON:0006450 name: second lumbar spinal cord segment subset: defined_by_ordinal_series synonym: "L2 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1345] synonym: "second lumbar spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1345] synonym: "l2 segment" EXACT [FMA:71188] xref: FMA:71188 ! l2 segment xref: NIF_GrossAnatomy:birnlex_1345 ! Second lumbar spinal cord segment is_a: UBERON:0007716 ! lumbar subsegment of spinal cord xref: SCTID:278777000 ! Second lumbar spinal cord segment [Term] id: UBERON:0006449 name: third lumbar spinal cord segment subset: defined_by_ordinal_series synonym: "L3 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1340] synonym: "third lumbar spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1340] synonym: "L3 segment" EXACT [FMA:71189] xref: FMA:71189 ! l3 segment xref: NIF_GrossAnatomy:birnlex_1340 ! Third lumbar spinal cord segment is_a: UBERON:0007716 ! lumbar subsegment of spinal cord xref: SCTID:278778005 ! Third lumbar spinal cord segment [Term] id: UBERON:0006451 name: fourth lumbar spinal cord segment subset: defined_by_ordinal_series synonym: "L4 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1352] synonym: "L4 segment" EXACT [FMA:71190] xref: FMA:71190 ! l4 segment xref: NIF_GrossAnatomy:birnlex_1352 ! Forth lumbar spinal cord segment is_a: UBERON:0007716 ! lumbar subsegment of spinal cord xref: SCTID:278779002 ! Fourth lumbar spinal cord segment [Term] id: UBERON:0006447 name: fifth lumbar spinal cord segment subset: defined_by_ordinal_series synonym: "L5 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1251] synonym: "fifth lumbar spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1251] synonym: "L5 segment" EXACT [FMA:71191] xref: FMA:71191 ! l5 segment xref: NIF_GrossAnatomy:birnlex_1251 ! Fifth lumbar spinal cord segment is_a: UBERON:0007716 ! lumbar subsegment of spinal cord xref: SCTID:278775008 ! Fifth lumbar spinal cord segment [Term] id: UBERON:0006457 name: first thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T1 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1452] synonym: "first thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1452] synonym: "t1 segment" EXACT [FMA:62421] xref: FMA:62421 ! t1 segment xref: NIF_GrossAnatomy:birnlex_1452 ! First thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278762008 ! First thoracic spinal cord segment [Term] id: UBERON:0006458 name: second thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T2 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1454] synonym: "second thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1454] synonym: "t2 segment" EXACT [FMA:62422] xref: FMA:62422 ! t2 segment xref: NIF_GrossAnatomy:birnlex_1454 ! Second thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278763003 ! Second thoracic spinal cord segment [Term] id: UBERON:0006459 name: third thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T3 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1458] synonym: "third thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1458] synonym: "t3 segment" EXACT [FMA:71169] xref: FMA:71169 ! t3 segment xref: NIF_GrossAnatomy:birnlex_1458 ! Third thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278764009 ! Third thoracic spinal cord segment [Term] id: UBERON:0006452 name: fourth thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T4 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1378] synonym: "T4 segment" EXACT [FMA:71170] xref: FMA:71170 ! t4 segment xref: NIF_GrossAnatomy:birnlex_1378 ! Forth thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278766006 ! Fourth thoracic spinal cord segment [Term] id: UBERON:0006453 name: fifth thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T5 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1383] synonym: "fifth thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1383] synonym: "t5 segment" EXACT [FMA:71171] xref: FMA:71171 ! t5 segment xref: NIF_GrossAnatomy:birnlex_1383 ! Fifth thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278767002 ! Fifth thoracic spinal cord segment [Term] id: UBERON:0006454 name: sixth thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T6 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1387] synonym: "sixth thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1387] synonym: "t6 segment" EXACT [FMA:71172] xref: FMA:71172 ! t6 segment xref: NIF_GrossAnatomy:birnlex_1387 ! Sixth thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278768007 ! Sixth thoracic spinal cord segment [Term] id: UBERON:0006455 name: seventh thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T7 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1392] synonym: "seventh thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1392] synonym: "t7 segment" EXACT [FMA:71173] xref: FMA:71173 ! t7 segment xref: NIF_GrossAnatomy:birnlex_1392 ! Seventh thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278769004 ! Seventh thoracic spinal cord segment [Term] id: UBERON:0006456 name: eighth thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T8 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1398] synonym: "eighth thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1398] synonym: "t8 segment" EXACT [FMA:71174] xref: FMA:71174 ! t8 segment xref: NIF_GrossAnatomy:birnlex_1398 ! Eighth thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278770003 ! Eighth thoracic spinal cord segment [Term] id: UBERON:0006465 name: ninth thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T9 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1584] synonym: "ninth thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1584] synonym: "t9 segment" EXACT [FMA:71175] xref: FMA:71175 ! t9 segment xref: NIF_GrossAnatomy:birnlex_1584 ! Ninth thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278771004 ! Ninth thoracic spinal cord segment [Term] id: UBERON:0006466 name: tenth thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T10 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1591] synonym: "tenth thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1591] synonym: "t10 segment" EXACT [FMA:71176] xref: FMA:71176 ! t10 segment xref: NIF_GrossAnatomy:birnlex_1591 ! Tenth thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278772006 ! Tenth thoracic spinal cord segment [Term] id: UBERON:0006467 name: eleventh thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T11 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1596] synonym: "eleventh thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1596] synonym: "t11 segment" EXACT [FMA:71177] xref: FMA:71177 ! t11 segment xref: NIF_GrossAnatomy:birnlex_1596 ! Eleventh thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278773001 ! Eleventh thoracic spinal cord segment [Term] id: UBERON:0006468 name: twelfth thoracic spinal cord segment subset: defined_by_ordinal_series synonym: "T12 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1598] synonym: "twelfth thoracic spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1598] synonym: "t12 segment" EXACT [FMA:71178] xref: FMA:71178 ! t12 segment xref: NIF_GrossAnatomy:birnlex_1598 ! Twelfth thoracic spinal cord segment is_a: UBERON:0007715 ! thoracic subsegment of spinal cord xref: SCTID:278774007 ! Twelfth thoracic spinal cord segment [Term] id: UBERON:0006460 name: first sacral spinal cord segment subset: defined_by_ordinal_series synonym: "S1 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1532] synonym: "first sacral spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1532] synonym: "S1 segment" EXACT [FMA:256625] xref: FMA:256625 ! s1 segment xref: NIF_GrossAnatomy:birnlex_1532 ! First sacral spinal cord segment is_a: UBERON:0007717 ! sacral subsegment of spinal cord xref: SCTID:278780004 ! First sacral spinal cord segment [Term] id: UBERON:0006461 name: second sacral spinal cord segment subset: defined_by_ordinal_series synonym: "S2 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1539] synonym: "second sacral spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1539] synonym: "S2 segment" EXACT [FMA:256627] xref: FMA:256627 ! s2 segment xref: NIF_GrossAnatomy:birnlex_1539 ! Second sacral spinal cord segment is_a: UBERON:0007717 ! sacral subsegment of spinal cord xref: SCTID:278781000 ! Second sacral spinal cord segment [Term] id: UBERON:0006462 name: third sacral spinal cord segment subset: defined_by_ordinal_series synonym: "S3 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1544] synonym: "third sacral spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1544] synonym: "S3 segment" EXACT [FMA:256629] xref: FMA:256629 ! s3 segment xref: NIF_GrossAnatomy:birnlex_1544 ! Third sacral spinal cord segment is_a: UBERON:0007717 ! sacral subsegment of spinal cord xref: SCTID:278782007 ! Third sacral spinal cord segment [Term] id: UBERON:0006463 name: fourth sacral spinal cord segment subset: defined_by_ordinal_series synonym: "S4 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1548] synonym: "S4 segment" EXACT [FMA:256631] xref: FMA:256631 ! s4 segment xref: NIF_GrossAnatomy:birnlex_1548 ! Forth sacral spinal cord segment is_a: UBERON:0007717 ! sacral subsegment of spinal cord xref: SCTID:278783002 ! Fourth sacral spinal cord segment [Term] id: UBERON:0006464 name: fifth sacral spinal cord segment subset: defined_by_ordinal_series synonym: "S5 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1553] synonym: "fifth sacral spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1553] synonym: "S5 segment" EXACT [FMA:256633] xref: FMA:256633 ! s5 segment xref: NIF_GrossAnatomy:birnlex_1553 ! Fifth sacral spinal cord segment is_a: UBERON:0007717 ! sacral subsegment of spinal cord xref: SCTID:278784008 ! Fifth sacral spinal cord segment [Term] id: UBERON:0006469 name: first cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C1 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1694] synonym: "first cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1694] synonym: "C1 segment" EXACT [FMA:71179] xref: FMA:71179 ! c1 segment xref: NIF_GrossAnatomy:birnlex_1694 ! First cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278754000 ! First cervical spinal cord segment [Term] id: UBERON:0006489 name: second cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C2 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_752] synonym: "second cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_752] synonym: "C2 segment" EXACT [FMA:71180] xref: FMA:71180 ! c2 segment xref: NIF_GrossAnatomy:birnlex_752 ! Second cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278755004 ! Second cervical spinal cord segment [Term] id: UBERON:0006488 name: third cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C3 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_744] synonym: "third cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_744] synonym: "C3 segment" EXACT [FMA:71181] xref: FMA:71181 ! c3 segment xref: NIF_GrossAnatomy:birnlex_744 ! Third cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278756003 ! Third cervical spinal cord segment [Term] id: UBERON:0006490 name: fourth cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C4 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_753] synonym: "forth cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_753] synonym: "C4 segment" EXACT [FMA:71182] xref: FMA:71182 ! c4 segment xref: NIF_GrossAnatomy:birnlex_753 ! Forth cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278757007 ! Fourth cervical spinal cord segment [Term] id: UBERON:0006491 name: fifth cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C5 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_760] synonym: "fifth cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_760] synonym: "C5 segment" EXACT [FMA:71183] xref: FMA:71183 ! c5 segment xref: NIF_GrossAnatomy:birnlex_760 ! Fifth cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278758002 ! Fifth cervical spinal cord segment [Term] id: UBERON:0006492 name: sixth cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C6 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_766] synonym: "sixth cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_766] synonym: "C6 segment" EXACT [FMA:71184] xref: FMA:71184 ! c6 segment xref: NIF_GrossAnatomy:birnlex_766 ! Sixth cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278759005 ! Sixth cervical spinal cord segment [Term] id: UBERON:0006493 name: seventh cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C7 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_773] synonym: "seventh cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_773] synonym: "C7 segment" EXACT [FMA:71185] xref: FMA:71185 ! c7 segment xref: NIF_GrossAnatomy:birnlex_773 ! Seventh cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278760000 ! Seventh cervical spinal cord segment [Term] id: UBERON:0006470 name: eighth cervical spinal cord segment subset: defined_by_ordinal_series synonym: "C8 spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1696] synonym: "eighth cervical spinal cord segment" EXACT [NIF_GrossAnatomy:birnlex_1696] synonym: "C8 segment" EXACT [FMA:71186] xref: FMA:71186 ! c8 segment xref: NIF_GrossAnatomy:birnlex_1696 ! Eighth cervical spinal cord segment is_a: UBERON:0007714 ! cervical subsegment of spinal cord xref: SCTID:278761001 ! Eighth cervical spinal cord segment [Term] id: UBERON:0006471 name: brodmann (1909) area 5 def: "Brodmann area 5 is one of Brodmann's cytologically defined regions of the brain. It is involved in somatosensory processing and association." [Wikipedia:Brodmann_area_5] synonym: "preparietal area 5" RELATED [Wikipedia:Brodmann_area_5] synonym: "secondary somatosensory cortex" RELATED [Wikipedia:Brodmann_area_5] synonym: "Area praeparietalis" EXACT [NIF_GrossAnatomy:birnlex_1736] synonym: "B09-5" EXACT [NIF_GrossAnatomy:birnlex_1736] synonym: "Brodmann area 5, preparietal" EXACT [NIF_GrossAnatomy:birnlex_1736] synonym: "area 5 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1736] synonym: "brodmann (1909) area 5" EXACT [NIF_GrossAnatomy:birnlex_1736] synonym: "preparietal area 5" EXACT [FMA:68601] synonym: "Brodmann area 5" EXACT [FMA:68601] synonym: "BA5" EXACT ABBREVIATION [] xref: FMA:68601 ! brodmann area 5 xref: NIF_GrossAnatomy:birnlex_1736 ! Brodmann (1909) area 5 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384764008 ! Entire Brodmann area 5, preparietal xref: http://upload.wikimedia.org/wikipedia/commons/5/52/Brodmann_areas_5.png [Term] id: UBERON:0006472 name: brodmann (1909) area 6 def: "Brodmann area 6, or BA6, is part of the frontal cortex in the human brain. Situated just anterior to the primary motor cortex, it is composed of the premotor cortex and, medially, the supplementary motor area, or SMA. This large area of the frontal cortex is believed to play a role in the planning of complex, coordinated movements. Brodmann area 6 is also called agranular frontal area 6 in humans because it lacks an internal granular cortical layer (layer IV). It is a subdivision of the cytoarchitecturally defined precentral region of cerebral cortex. In the human brain, it is located on the portions of the precentral gyrus that are not occupied by the gigantopyramidal area 4; furthermore, BA6 extends onto the caudal portions of the superior frontal and middle frontal gyri. It extends from the cingulate sulcus on the medial aspect of the hemisphere to the lateral sulcus on the lateral aspect. It is bounded rostrally by the granular frontal region and caudally by the gigantopyramidal area 4 (Brodmann, 1909)." [Wikipedia:Brodmann_area_6] synonym: "agranular frontal area 6" RELATED [Wikipedia:Brodmann_area_6] synonym: "Area frontalis agranularis" EXACT [NIF_GrossAnatomy:birnlex_1737] synonym: "B09-6" EXACT [NIF_GrossAnatomy:birnlex_1737] synonym: "Brodmann area 6, agranular frontal" EXACT [NIF_GrossAnatomy:birnlex_1737] synonym: "area 6 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1737] synonym: "brodmann (1909) area 6" EXACT [NIF_GrossAnatomy:birnlex_1737] synonym: "agranular frontal area 6" EXACT [FMA:68602] synonym: "area 6 of brodmann" EXACT [FMA:68602] synonym: "frontal belt" EXACT [FMA:68602] synonym: "Brodmann area 6" EXACT [FMA:68602] synonym: "BA6" EXACT ABBREVIATION [] xref: FMA:68602 ! brodmann area 6 xref: NIF_GrossAnatomy:birnlex_1737 ! Brodmann (1909) area 6 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384765009 ! Entire Brodmann area 6, agranular frontal xref: http://upload.wikimedia.org/wikipedia/commons/1/11/Brodmann_areas_6.png [Term] id: UBERON:0006473 name: brodmann (1909) area 18 def: "" [Wikipedia:Brodmann_area_18] synonym: "Area parastriata" EXACT LATIN [Wikipedia:Brodmann_area_18] synonym: "Area parastriata" EXACT [NIF_GrossAnatomy:birnlex_1749] synonym: "B09-18" EXACT [NIF_GrossAnatomy:birnlex_1749] synonym: "Brodmann area 18, parastriate" EXACT [NIF_GrossAnatomy:birnlex_1749] synonym: "area 18 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1749] synonym: "brodmann (1909) area 18" EXACT [NIF_GrossAnatomy:birnlex_1749] synonym: "area 18 of brodmann" EXACT [FMA:68615] synonym: "brodmann's area 18" EXACT [FMA:68615] synonym: "parastriate area 18" EXACT [FMA:68615] synonym: "secondary visual area" EXACT [FMA:68615] synonym: "visual area ii" EXACT [FMA:68615] synonym: "Brodmann area 18" EXACT [FMA:68615] synonym: "BA18" EXACT ABBREVIATION [] xref: FMA:68615 ! brodmann area 18 xref: NIF_GrossAnatomy:birnlex_1749 ! Brodmann (1909) area 18 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384773000 ! Entire Brodmann area 18, parastriate [Term] id: UBERON:0006474 name: brodmann (1909) area 30 def: "Brodmann area 30, also known as agranular retrolimbic area 30, is a subdivision of the cytoarchitecturally defined retrosplenial region of the cerebral cortex. In the human it is located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the granular retrolimbic area 29, dorsally by the ventral posterior cingulate area 23 and ventrolaterally by the ectorhinal area 36 (Brodmann-1909)." [Wikipedia:Brodmann_area_30] synonym: "Area retrosplenialis agranularis" EXACT LATIN [Wikipedia:Brodmann_area_30] synonym: "Area retrolimbica agranularis" EXACT [NIF_GrossAnatomy:birnlex_1764] synonym: "B09-30" EXACT [NIF_GrossAnatomy:birnlex_1764] synonym: "Brodmann area 30, agranular retrolimbic" EXACT [NIF_GrossAnatomy:birnlex_1764] synonym: "area 30 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1764] synonym: "brodmann (1909) area 30" EXACT [NIF_GrossAnatomy:birnlex_1764] synonym: "agranular retrolimbic area 30" EXACT [FMA:68627] synonym: "area 30 of brodmann" EXACT [FMA:68627] synonym: "brodmann's area 30" EXACT [FMA:68627] synonym: "Brodmann area 30" EXACT [FMA:68627] synonym: "BA30" EXACT ABBREVIATION [] xref: FMA:68627 ! brodmann area 30 xref: NIF_GrossAnatomy:birnlex_1764 ! Brodmann (1909) area 30 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384784007 ! Entire Brodmann area 30, agranular retrolimbic [Term] id: UBERON:0006475 name: brodmann (1909) area 31 def: "Brodmann area 31, also known as dorsal posterior cingulate area 31, is a subdivision of the cytoarchitecturally defined cingulate region of the cerebral cortex. In the human it occupies portions of the posterior cingulate gyrus and medial aspect of the parietal lobe. Approximate boundaries are the cingulate sulcus dorsally and the parieto-occipital sulcus caudally. It partially surrounds the subparietal sulcus, the ventral continuation of the cingulate sulcus in the parietal lobe. Cytoarchitecturally it is bounded rostrally by the ventral anterior cingulate area 24, ventrally by the ventral posterior cingulate area 23, dorsally by the gigantopyramidal area 4 and preparietal area 5 and caudally by the superior parietal area 7 (H) (Brodmann-1909)." [Wikipedia:Brodmann_area_31] synonym: "Area cingularis posterior dorsalis" EXACT LATIN [Wikipedia:Brodmann_area_31] xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Brodmann_Cytoarchitectonics_31.png synonym: "Area cingularis posterior dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1765] synonym: "B09-31" EXACT [NIF_GrossAnatomy:birnlex_1765] synonym: "Brodmann area 31, dorsal posterior cingulate" EXACT [NIF_GrossAnatomy:birnlex_1765] synonym: "area 31 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1765] synonym: "brodmann (1909) area 31" EXACT [NIF_GrossAnatomy:birnlex_1765] synonym: "area 31 of brodmann" EXACT [FMA:68628] synonym: "brodmann's area 31" EXACT [FMA:68628] synonym: "cinguloparietal transition area" EXACT [FMA:68628] synonym: "dorsal posterior cingulate area 31" EXACT [FMA:68628] synonym: "Brodmann area 31" EXACT [FMA:68628] synonym: "BA31" EXACT ABBREVIATION [] xref: FMA:68628 ! brodmann area 31 xref: NIF_GrossAnatomy:birnlex_1765 ! Brodmann (1909) area 31 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384785008 ! Entire Brodmann area 31, dorsal posterior cingulate [Term] id: UBERON:0006476 name: brodmann (1909) area 33 def: "Brodmann area 33, also known as pregenual area 33, is a subdivision of the cytoarchitecturally defined cingulate region of cerebral cortex. It is a narrow band located in the anterior cingulate gyrus adjacent to the supracallosal gyrus in the depth of the callosal sulcus, near the genu of the corpus callosum. Cytoarchitecturally it is bounded by the ventral anterior cingulate area 24 and the supracallosal gyrus (Brodmann-1909)." [Wikipedia:Brodmann_area_33] synonym: "Area praegenualis" EXACT LATIN [Wikipedia:Brodmann_area_33] synonym: "Area praegenualis" EXACT [NIF_GrossAnatomy:birnlex_1766] synonym: "B09-33" EXACT [NIF_GrossAnatomy:birnlex_1766] synonym: "Brodmann area 33, pregenual" EXACT [NIF_GrossAnatomy:birnlex_1766] synonym: "area 33 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1766] synonym: "brodmann (1909) area 33" EXACT [NIF_GrossAnatomy:birnlex_1766] synonym: "area 33 of brodmann" EXACT [FMA:68630] synonym: "brodmann's area 33" EXACT [FMA:68630] synonym: "pregenual area 33" EXACT [FMA:68630] synonym: "Brodmann area 33" EXACT [FMA:68630] synonym: "BA33" EXACT ABBREVIATION [] xref: FMA:68630 ! brodmann area 33 xref: NIF_GrossAnatomy:birnlex_1766 ! Brodmann (1909) area 33 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384788005 ! Entire Brodmann area 33, pregenual [Term] id: UBERON:0006477 name: brodmann (1909) area 34 def: "Brodmann area 34 is a part of the brain. It has been described as part of the entorhinal area. It has been described as part of the superior temporal gyrus." [Wikipedia:Brodmann_area_34] synonym: "Area entorhinalis dorsalis" EXACT LATIN [Wikipedia:Brodmann_area_34] synonym: "Area entorhinalis dorsalis" EXACT [NIF_GrossAnatomy:birnlex_1767] synonym: "B09-34" EXACT [NIF_GrossAnatomy:birnlex_1767] synonym: "Brodmann area 34, dorsal entorhinal" EXACT [NIF_GrossAnatomy:birnlex_1767] synonym: "area 34 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1767] synonym: "brodmann (1909) area 34" EXACT [NIF_GrossAnatomy:birnlex_1767] synonym: "area 34 of brodmann" EXACT [FMA:68631] synonym: "dorsal entorhinal area 34" EXACT [FMA:68631] synonym: "Brodmann area 34" EXACT [FMA:68631] synonym: "BA34" EXACT ABBREVIATION [] xref: FMA:68631 ! brodmann area 34 xref: NIF_GrossAnatomy:birnlex_1767 ! Brodmann (1909) area 34 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384789002 ! Entire Brodmann area 34, dorsal entorhinal [Term] id: UBERON:0006478 name: brodmann (1909) area 37 def: "Brodmann area 37, or BA37, is part of the temporal cortex in the human brain. This area is known as occipitotemporal area 37 (H). It is a subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. It is located primarily in the caudal portions of the fusiform gyrus and inferior temporal gyrus on the mediobasal and lateral surfaces at the caudal extreme of the temporal lobe. Cytoarchitecturally it is bounded caudally by the peristriate Brodmann area 19, rostrally by the inferior temporal area 20 and middle temporal area 21 and dorsally on the lateral aspect of the hemisphere by the angular area 39 (H) (Brodmann-1909)." [Wikipedia:Brodmann_area_37] synonym: "Area occipitotemporalis" EXACT LATIN [Wikipedia:Brodmann_area_37] synonym: "Area occipitotemporalis" EXACT [NIF_GrossAnatomy:birnlex_1770] synonym: "B09-37" EXACT [NIF_GrossAnatomy:birnlex_1770] synonym: "Brodmann area 37, occipitotemporal" EXACT [NIF_GrossAnatomy:birnlex_1770] synonym: "area 37 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1770] synonym: "brodmann (1909) area 37" EXACT [NIF_GrossAnatomy:birnlex_1770] synonym: "area 37 0f brodmann" EXACT [FMA:68634] synonym: "occipitotemporal area 37" EXACT [FMA:68634] synonym: "Brodmann area 37" EXACT [FMA:68634] synonym: "BA37" EXACT ABBREVIATION [] xref: FMA:68634 ! brodmann area 37 xref: NIF_GrossAnatomy:birnlex_1770 ! Brodmann (1909) area 37 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384792003 ! Entire Brodmann area 37, occipitotemporal [Term] id: UBERON:0006479 name: brodmann (1909) area 38 synonym: "Area temporopolaris" EXACT [NIF_GrossAnatomy:birnlex_1771] synonym: "B09-38" EXACT [NIF_GrossAnatomy:birnlex_1771] synonym: "Brodmann area 38, temporopolar" EXACT [NIF_GrossAnatomy:birnlex_1771] synonym: "area 38 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1771] synonym: "brodmann (1909) area 38" EXACT [NIF_GrossAnatomy:birnlex_1771] synonym: "area 38 of brodmann" EXACT [FMA:68635] synonym: "temporopolar area 38" EXACT [FMA:68635] synonym: "Brodmann area 38" EXACT [FMA:68635] synonym: "BA38" EXACT ABBREVIATION [] xref: FMA:68635 ! brodmann area 38 xref: NIF_GrossAnatomy:birnlex_1771 ! Brodmann (1909) area 38 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384793008 ! Entire Brodmann area 38, temporopolar [Term] id: UBERON:0006480 name: brodmann (1909) area 39 def: "." [Wikipedia:Brodmann_area_39] synonym: "Area angularis" EXACT [NIF_GrossAnatomy:birnlex_1772] synonym: "B09-39" EXACT [NIF_GrossAnatomy:birnlex_1772] synonym: "Brodmann area 39, angular" EXACT [NIF_GrossAnatomy:birnlex_1772] synonym: "area 39 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1772] synonym: "brodmann (1909) area 39" EXACT [NIF_GrossAnatomy:birnlex_1772] synonym: "angular area 39" EXACT [FMA:68636] synonym: "area 39 of brodmann" EXACT [FMA:68636] synonym: "Brodmann area 39" EXACT [FMA:68636] synonym: "BA39" EXACT ABBREVIATION [] xref: FMA:68636 ! brodmann area 39 xref: NIF_GrossAnatomy:birnlex_1772 ! Brodmann (1909) area 39 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384794002 ! Entire Brodmann area 39, angular [Term] id: UBERON:0006481 name: brodmann (1909) area 44 synonym: "Area opercularis" EXACT [NIF_GrossAnatomy:birnlex_1776] synonym: "B09-44" EXACT [NIF_GrossAnatomy:birnlex_1776] synonym: "Brodmann area 44, opercular" EXACT [NIF_GrossAnatomy:birnlex_1776] synonym: "area 44 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1776] synonym: "brodmann (1909) area 44" EXACT [NIF_GrossAnatomy:birnlex_1776] synonym: "area 44 of brodmann" EXACT [FMA:68641] synonym: "opercular area 44" EXACT [FMA:68641] synonym: "Brodmann area 44" EXACT [FMA:68641] synonym: "BA44" EXACT ABBREVIATION [] xref: FMA:68641 ! brodmann area 44 xref: NIF_GrossAnatomy:birnlex_1776 ! Brodmann (1909) area 44 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384803008 ! Entire Brodmann area 44, opercular [Term] id: UBERON:0006482 name: brodmann (1909) area 45 def: "Brodmann area 45 (BA45), is part of the frontal cortex in the human brain. Situated on the lateral surface, inferior to BA9 and adjacent to BA46. This area is also known as pars triangular (of the inferior frontal gyrus). In the human, it occupies the triangular part of inferior frontal gyrus (H) and, surrounding the anterior horizontal limb of lateral sulcus (H), a portion of the orbital part of inferior frontal gyrus (H). Bounded caudally by the anterior ascending limb of lateral sulcus (H), it borders on the insula in the depth of the lateral sulcus. In terms of cytoarchitecture, it is bounded caudally by the opercular area 44 (BA44), rostrodorsally by the middle frontal area 46 (BA46), and ventrally by the orbital area 47 (BA47) (Brodmann-1909)." [Wikipedia:Brodmann_area_45] synonym: "Area triangularis" EXACT LATIN [Wikipedia:Brodmann_area_45] synonym: "Area triangularis" EXACT [NIF_GrossAnatomy:birnlex_1777] synonym: "B09-45" EXACT [NIF_GrossAnatomy:birnlex_1777] synonym: "Brodmann area 45, triangular" EXACT [NIF_GrossAnatomy:birnlex_1777] synonym: "area 45 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1777] synonym: "brodmann (1909) area 45" EXACT [NIF_GrossAnatomy:birnlex_1777] synonym: "area 45 of brodmann" EXACT [FMA:68642] synonym: "triangular area 45" EXACT [FMA:68642] synonym: "Brodmann area 45" EXACT [FMA:68642] synonym: "BA45" EXACT ABBREVIATION [] xref: FMA:68642 ! brodmann area 45 xref: NIF_GrossAnatomy:birnlex_1777 ! Brodmann (1909) area 45 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384805001 ! Entire Brodmann area 45, triangular [Term] id: UBERON:0006483 ! brodmann (1909) area 46 name: brodmann (1909) area 46 def: "Brodmann area 46, or BA46, is part of the frontal cortex in the human brain. It is between BA10 and BA45. BA46 is known as middle frontal area 46. In the human it occupies approximately the middle third of the middle frontal gyrus and the most rostral portion of the inferior frontal gyrus. Brodmann area 46 roughly corresponds with the dorsolateral prefrontal cortex (DLPFC), although the borders of area 46 are based on cytoarchitecture rather than function. The DLPFC also encompasses part of granular frontal area 9, directly adjacent on the dorsal surface of the cortex. Cytoarchitecturally, BA46 is bounded dorsally by the granular frontal area 9, rostroventrally by the frontopolar area 10 and caudally by the triangular area 45 (Brodmann-1909). There is some discrepancy between the extent of BA8 (Brodmann-1905) and the same area as described by Walker (1940)" [Wikipedia:Brodmann_area_46] synonym: "middle frontal area 46" RELATED [Wikipedia:Brodmann_area_46] synonym: "Area frontalis media" EXACT [NIF_GrossAnatomy:birnlex_1778] synonym: "B09-46" EXACT [NIF_GrossAnatomy:birnlex_1778] synonym: "Brodmann area 46, middle frontal" EXACT [NIF_GrossAnatomy:birnlex_1778] synonym: "area 46 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1778] synonym: "brodmann (1909) area 46" EXACT [NIF_GrossAnatomy:birnlex_1778] synonym: "area 46 of brodmann" EXACT [FMA:68643] synonym: "middle frontal area 46" EXACT [FMA:68643] synonym: "Brodmann area 46" EXACT [FMA:68643] synonym: "BA46" EXACT ABBREVIATION [] xref: FMA:68643 ! brodmann area 46 xref: NIF_GrossAnatomy:birnlex_1778 ! Brodmann (1909) area 46 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384806000 ! Entire Brodmann area 46, middle frontal xref: http://upload.wikimedia.org/wikipedia/commons/c/cd/Brodmann_area_46.png [Term] id: UBERON:0009834 ! dorsolateral prefrontal cortex name: dorsolateral prefrontal cortex def: "The dorsolateral prefrontal cortex (DL-PFC or DLPFC), according to a more restricted definition, is roughly equivalent to Brodmann areas 9 and 46.[1] According to a broader definition DL-PFC consists of the lateral portions of Brodmann areas 9 – 12, of areas 45, 46, and the superior part of area 47.[2] These regions mainly receive their blood supply from the middle cerebral artery. With respect to neurotransmitter systems, there is evidence that dopamine plays a particularly important role in DL-PFC.[2]DL-PFC is connected to the orbitofrontal cortex, and to a variety of brain areas, which include the thalamus, parts of the basal ganglia (the dorsal caudate nucleus), the hippocampus, and primary and secondary association areas of neocortex, including posterior temporal, parietal, and occipital areas" [Wikipedia:Dorsolateral_prefrontal_cortex] comment: check dorsolateral prefrontal neocortex is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex relationship: overlaps UBERON:0006483 ! brodmann (1909) area 46 [Term] id: UBERON:0006484 name: brodmann (1909) area 47 def: "Brodmann area 47, or BA47, is part of the frontal cortex in the human brain. Curving from the lateral surface of the frontal lobe into the ventral (orbital) frontal cortex. It is below areas BA10 and BA45, and beside BA11. This area is also known as orbital area 47. In the human, on the orbital surface it surrounds the caudal portion of the orbital sulcus (H) from which it extends laterally into the orbital part of inferior frontal gyrus (H). Cytoarchitectonically it is bounded caudally by the triangular area 45, medially by the prefrontal area 11 of Brodmann-1909, and rostrally by the frontopolar area 10 (Brodmann-1909). It incorporates the region that Brodmann identified as \"Area 12\" in the monkey, and therefore, following the suggestion of Michael Petrides, some contemporary neuroscientists refer to the region as \"BA47/12. \" BA47 has been implicated in the processing of syntax in spoken and signed languages, and more recently in musical syntax." [Wikipedia:Brodmann_area_47] synonym: "Area orbitalis" EXACT LATIN [Wikipedia:Brodmann_area_47] synonym: "Area orbitalis" EXACT [NIF_GrossAnatomy:birnlex_1779] synonym: "B09-47" EXACT [NIF_GrossAnatomy:birnlex_1779] synonym: "Brodmann area 47, orbital" EXACT [NIF_GrossAnatomy:birnlex_1779] synonym: "area 47 of Brodmann-1909" EXACT [NIF_GrossAnatomy:birnlex_1779] synonym: "brodmann (1909) area 47" EXACT [NIF_GrossAnatomy:birnlex_1779] synonym: "area 47 of brodmann" EXACT [FMA:68644] synonym: "orbital area 47" EXACT [FMA:68644] synonym: "Brodmann area 47" EXACT [FMA:68644] synonym: "BA47" EXACT ABBREVIATION [] xref: FMA:68644 ! brodmann area 47 xref: NIF_GrossAnatomy:birnlex_1779 ! Brodmann (1909) area 47 is_a: UBERON:0002619 ! regional part of cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex xref: SCTID:384807009 ! Entire Brodmann area 47, orbital [Term] id: UBERON:0006485 name: brodmann (1909) area 48 def: "Retrosubicular area 48 is a subdivision of the cytoarchitecturally defined hippocampal region of the cerebral cortex. In the human it is located on the medial surface of the temporal lobe. Cytoarchitectually it is bounded rostrally by the perirhinal area 35 and medially by the presubiculum. While described by Brodmann (Brodmann-1909), it was not included in his areal maps of human cortex (Brodmann-1909; Brodmann-1910)." [Wikipedia:Brodmann_area_48] synonym: "Area retrosubicularis" EXACT [NIF_GrossAnatomy:birnlex_1791] synonym: "B09-48" EXACT [NIF_GrossAnatomy:birnlex_1791] synonym: "Brodmann area 48, retrosubicular" EXACT [NIF_GrossAnatomy:birnlex_1791] synonym: "brodmann (1909) area 48" EXACT [NIF_GrossAnatomy:birnlex_1791] synonym: "area 48 of brodmann" EXACT [FMA:81151] synonym: "brodmann's area 48" EXACT [FMA:81151] synonym: "retrosubicular area 48" EXACT [FMA:81151] synonym: "Brodmann area 48" EXACT [FMA:81151] synonym: "BA48" EXACT ABBREVIATION [] xref: FMA:81151 ! brodmann area 48 xref: NIF_GrossAnatomy:birnlex_1791 ! Brodmann (1909) area 48 is_a: UBERON:0002619 ! regional part of cerebral cortex xref: SCTID:384808004 ! Entire Brodmann area 48, retrosubicular [Term] id: UBERON:0006486 name: brodmann (1909) area 52 synonym: "Area parainsularis" EXACT [NIF_GrossAnatomy:birnlex_1792] synonym: "B09-52" EXACT [NIF_GrossAnatomy:birnlex_1792] synonym: "Brodmann area 52, parainsular" EXACT [NIF_GrossAnatomy:birnlex_1792] synonym: "brodmann (1909) area 52" EXACT [NIF_GrossAnatomy:birnlex_1792] synonym: "area 52 of brodmann" EXACT [FMA:81153] synonym: "parainsular area 52" EXACT [FMA:81153] synonym: "Brodmann area 52" EXACT [FMA:81153] synonym: "BA52" EXACT ABBREVIATION [] xref: FMA:81153 ! brodmann area 52 xref: NIF_GrossAnatomy:birnlex_1792 ! Brodmann (1909) area 52 is_a: UBERON:0002619 ! regional part of cerebral cortex xref: SCTID:384809007 ! Entire Brodmann area 52, parainsular [Term] id: UBERON:0006487 name: hadjikhani et al. (1998) visuotopic area v2d synonym: "hadjikhani et al. (1998) visuotopic area v2d" EXACT [NIF_GrossAnatomy:birnlex_4055] xref: NIF_GrossAnatomy:birnlex_4055 ! Hadjikhani et al. (1998) Visuotopic area V2d is_a: UBERON:0003022 ! lobe parts of cerebral cortex [Term] id: UBERON:0006494 name: apex of arytenoid synonym: "arytenoid cartilage apex" EXACT [FMA:55348] synonym: "apex of arytenoid cartilage" EXACT [FMA:55348] xref: FMA:55348 ! Apex of arytenoid cartilage xref: MA:0001760 ! apex of arytenoid is_a: UBERON:0001996 ! elastic cartilage relationship: part_of UBERON:0001740 ! arytenoid cartilage xref: SCTID:279534007 ! Entire apex of arytenoid cartilage [Term] id: UBERON:0006495 name: osseus cochlear canal synonym: "osseous cochlear canal" EXACT [FMA:75666] xref: FMA:75666 ! Osseous cochlear canal xref: MA:0001183 ! osseus cochlear canal is_a: UBERON:0005744 ! cranial conduit [Term] id: UBERON:0006496 name: external acoustic meatus osseus part synonym: "osseous external acoustic meatus" EXACT [] synonym: "osseous part of external acoustic meatus" EXACT [FMA:61290] synonym: "osseous external acoustic tube" EXACT [FMA:61290] xref: FMA:61290 ! Osseous external acoustic tube xref: MA:0001235 ! external acoustic meatus osseus part is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001352 ! external acoustic meatus [Term] id: UBERON:0006508 ! interosseus muscle name: interosseus muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0006497 ! pes interosseus muscle name: pes interosseus muscle synonym: "foot interosseous" EXACT [FMA:37456] synonym: "interosseous of foot" EXACT [FMA:37456] xref: FMA:37456 ! Interosseous of foot xref: MA:0002302 ! foot interosseus muscle intersection_of: UBERON:0006508 ! interosseus muscle intersection_of: part_of UBERON:0002387 ! pes xref: ncithesaurus:Foot_Interosseous_Muscle ! Foot Interosseous Muscle xref: SCTID:181714004 ! Interosseous muscle of foot synonym: "foot interosseus muscle" EXACT [MA:0002302] def: "An interosseus muscle that is part of a pes." [OBOL:automatic] xref: UMLS:C0448494 [Term] id: UBERON:0006499 name: dorsal pes interosseus muscle def: "In human anatomy, the dorsal interossei of the foot are four muscles situated between the metatarsal bones." [Wikipedia:Dorsal_interossei_of_the_foot] synonym: "musculi interossei dorsalis pedis" EXACT [] synonym: "dorsal interosseous of foot" EXACT [FMA:37457] xref: FMA:37457 ! Dorsal interosseous of foot xref: MA:0002303 ! dorsal foot interosseus muscle is_a: UBERON:0006497 ! pes interosseus muscle xref: ncithesaurus:Dorsal_Foot_Interosseous_Muscle ! Dorsal Foot Interosseous Muscle relationship: has_muscle_insertion UBERON:0004302 {source="dbpedia"} ! proximal phalanx relationship: has_muscle_origin UBERON:0000983 {source="dbpedia"} ! metatarsus region relationship: has_muscle_antagonist UBERON:0006502 {source="dbpedia"} ! plantar foot interosseus muscle synonym: "musculi interossei dorsalis pedis" RELATED LATIN [Wikipedia:Dorsal_interossei_of_the_foot] xref: http://upload.wikimedia.org/wikipedia/commons/5/57/Gray446.png synonym: "dorsal foot interosseus muscle" EXACT [MA:0002303] xref: UMLS:C1744541 [Term] id: UBERON:0006502 name: plantar foot interosseus muscle def: "The plantar interossei, three in number, lie beneath rather than between the metatarsal bones, and each is connected with but one metatarsal bone. They arise from the bases and medial sides of the bodies of the third, fourth, and fifth metatarsal bones, and are inserted into the medial sides of the bases of the first phalanges of the same toes, and into the aponeuroses of the tendons of the Extensor digitorum longus." [Wikipedia:Plantar_interossei_muscles] synonym: "plantar interosseous of foot" EXACT [FMA:37458] synonym: "musculi interossei plantares" EXACT [] xref: FMA:37458 ! Plantar interosseous of foot xref: MA:0002304 ! plantar foot interosseus muscle is_a: UBERON:0006497 ! foot interosseus muscle xref: ncithesaurus:Plantar_Foot_Interosseus_Muscle ! Plantar Foot Interosseus Muscle relationship: has_muscle_insertion UBERON:0004302 {source="dbpedia"} ! proximal phalanx relationship: has_muscle_origin UBERON:0000983 {source="dbpedia"} ! metatarsus region relationship: has_muscle_antagonist UBERON:0006499 {source="dbpedia"} ! dorsal pes interosseus muscle synonym: "musculi interosseus plantaris" RELATED LATIN [Wikipedia:Plantar_interossei_muscles] xref: http://upload.wikimedia.org/wikipedia/commons/2/21/Gray447.png xref: UMLS:C1744540 [Term] id: UBERON:0006505 name: palmar hand interosseus muscle def: "The palmar interossei (interossei volares) are small muscles in the hand that lie on the anterior aspect of the metacarpals. They are smaller than the dorsal interossei of the hand, which lie between the metacarpals" [Wikipedia:Palmar_interossei_muscles] synonym: "palmar interosseous of hand" EXACT [FMA:37419] synonym: "musculi interossei palmares" EXACT [] xref: FMA:37419 ! Palmar interosseous of hand xref: MA:0002315 ! palmar hand interosseus muscle is_a: UBERON:0001502 ! interosseous muscle of manus xref: ncithesaurus:Palmar_Hand_Interosseus_Muscle ! Palmar Hand Interosseus Muscle relationship: has_muscle_insertion UBERON:0004302 {source="dbpedia"} ! proximal phalanx relationship: has_muscle_origin UBERON:0010544 {source="dbpedia"} ! metacarpal skeleton synonym: "musculi interossei palmares" RELATED LATIN [Wikipedia:Palmar_interossei_muscles] xref: http://upload.wikimedia.org/wikipedia/commons/3/39/Gray429.png xref: UMLS:C1709453 [Term] id: UBERON:0006535 name: skin fluid/secretion synonym: "skin fluid" RELATED [] synonym: "skin secretion" RELATED [] xref: MA:0002537 intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0000014 ! zone of skin def: "A portion of organism substance that secreted_by a zone of skin." [OBOL:automatic] [Term] id: UBERON:0006536 name: male reproductive system fluid/secretion synonym: "male reproductive system fluid" RELATED [] synonym: "male reproductive system secretion" RELATED [] xref: MA:0002521 intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0000079 ! male reproductive system def: "A portion of organism substance that secreted_by a male reproductive system." [OBOL:automatic] [Term] id: UBERON:0006537 name: female reproductive system fluid/secretion synonym: "female reproductive system fluid" RELATED [] synonym: "female reproductive system secretion" RELATED [] xref: MA:0002510 intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0000474 ! female reproductive system def: "A portion of organism substance that secreted_by a female reproductive system." [OBOL:automatic] [Term] id: UBERON:0006538 name: respiratory system fluid/secretion synonym: "respiratory system fluid" RELATED [] synonym: "respiratory system secretion" RELATED [] xref: MA:0002533 xref: ncithesaurus:Respiratory_System_Fluid_or_Secretion ! respiratory system fluid or secretion intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0001004 ! respiratory system def: "A portion of organism substance that secreted_by a respiratory system." [OBOL:automatic] xref: UMLS:C1514899 [Term] id: UBERON:0007311 name: sputum def: "Matter ejected from the lungs, bronchi, and trachea, through the mouth." [Dorlands_Medical_Dictionary:MerckSource] synonym: "expectoration" RELATED [BTO:0001297] xref: BTO:0001297 ! sputum xref: MA:0002536 ! sputum xref: MESH:A12.200.808 xref: GAID:1171 ! sputum is_a: UBERON:0006538 ! respiratory system fluid/secretion relationship: part_of UBERON:0006524 ! alveolar system xref: ncithesaurus:Sputum ! Sputum xref: UMLS:C0038056 [Term] id: UBERON:0006539 name: mammary gland fluid/secretion synonym: "mammary gland fluid" RELATED [] synonym: "mammary gland secretion" RELATED [] synonym: "secretion of mammary gland" RELATED [] synonym: "lactiferous gland fluid" RELATED [] synonym: "lactiferous gland secretion" RELATED [] xref: MA:0002505 ! mammary gland fluid/secretion intersection_of: UBERON:0000463 ! portion of organism substance intersection_of: secreted_by UBERON:0001911 ! mammary gland def: "A portion of organism substance that secreted_by a mammary gland." [OBOL:automatic] [Term] id: UBERON:0001913 ! milk name: milk def: "Secretion produced by the mammary gland.[FMA]" [Wikipedia:Breast_milk, FMA:FMA] comment: AO notes: ncit:Milk refers specifically to cow milk subset: uberon_slim synonym: "mammary gland milk" EXACT [] xref: BTO:0000868 xref: ENVO:02000031 xref: FMA:62100 ! Milk xref: GAID:1230 ! milk xref: VHOG:0001263 ! milk xref: MA:0002552 ! mammary gland milk xref: MAT:0000056 ! milk xref: MIAA:0000056 ! milk xref: OpenCyc:Mx4rvVjGZJwpEbGdrcN5Y29ycA xref: ncithesaurus:Breast_Fluid_or_Secretion ! breast fluid or secretion xref: galen:Milk ! milk xref: MESH:A13.622 ! milk xref: EV:0100126 ! milk is_a: UBERON:0000456 ! bodily secretion relationship: secreted_by UBERON:0001911 ! mammary gland property_value: homology_notes "The detailed similarities of mammary glands in living monotremes, marsupials, and eutherians argue for a monophyletic origin of these glands, perhaps by the combination of parts of preexisting sebaceous and sweat glands.[well established][VHOG]" xsd:string {external_class="VHOG:0001263", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV\, Vertebrates: Comparative Anatomy\, Function\, Evolution (2006) p.224", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1511310 [Term] id: UBERON:0001914 name: colostrum def: "The thin, yellow, serous fluid secreted by the mammary glands during pregnancy and immediately postpartum before lactation begins. It consists of immunologically active substances, white blood cells, water, protein, fat, and carbohydrates." [MESH:A12.200.194, Wikipedia:Colostrum] comment: AO notes: we follow in MA in making this is a sib of mammary gland milk, rather than a subclass. subset: uberon_slim xref: BTO:0000276 xref: FMA:62101 ! Colostrum xref: GAID:1159 ! colostrum xref: MA:0002551 ! colostrum xref: ncithesaurus:Colostrum ! Colostrum xref: MESH:A12.200.194 ! colostrum is_a: UBERON:0000456 ! bodily secretion relationship: secreted_by UBERON:0001911 ! mammary gland property_value: has_relational_adjective "colostral" xsd:string xref: UMLS:C0009413 [Term] id: UBERON:0006541 name: outer medulla inner stripe loop of henle xref: MA:0002627 xref: EMAPA:29679 ! loop of Henle of inner stripe of outer medulla (also: UBERON:0001288 'loop of Henle') intersection_of: UBERON:0001288 ! loop of Henle intersection_of: part_of UBERON:0004201 ! inner stripe def: "A loop of Henle that is part of a kidney outer medulla inner stripe." [OBOL:automatic] [Term] id: UBERON:0006542 name: outer medulla outer stripe loop of henle xref: MA:0002630 xref: EMAPA:29665 ! loop of Henle of outer stripe of outer medulla (also: UBERON:0001288 'loop of Henle') intersection_of: UBERON:0001288 ! loop of Henle intersection_of: part_of UBERON:0004202 ! outer stripe def: "A loop of Henle that is part of a kidney outer medulla outer stripe." [OBOL:automatic] [Term] id: UBERON:0006564 name: superficial palmar arch synonym: "Superficial palmar arch" EXACT [FMA:22834] synonym: "superficial palmar arterial arch" EXACT [FMA:22834] xref: FMA:22834 ! Superficial palmar arterial arch xref: MA:0002127 ! superficial palmar arch is_a: UBERON:0004563 ! forelimb digital vein synonym: "arcus palmaris superficialis" EXACT LATIN [FMA:TA, FMA:22834] xref: ncithesaurus:Superficial_Palmar_Arch ! Superficial Palmar Arch xref: SCTID:362051006 ! Entire superficial palmar arch xref: UMLS:C0226433 [Term] id: UBERON:0006566 name: left ventricle myocardium def: "Myocardium of ventricle which is continuous with the tunica media of aorta.[FMA]" [FMA:9558, FMA:FMA] synonym: "Left ventricular myocardium" EXACT [FMA:9558] synonym: "myocardium of left ventricle" EXACT [FMA:9558] xref: FMA:9558 ! Myocardium of left ventricle xref: MA:0002983 ! left ventricle myocardium intersection_of: UBERON:0001083 ! myocardium of ventricle intersection_of: part_of UBERON:0002084 ! left ventricle relationship: continuous_with UBERON:0003618 ! aorta tunica media xref: SCTID:362021000 ! Entire myocardium of left ventricle [Term] id: UBERON:0006567 name: right ventricle myocardium def: "Myocardium of ventricle which is continuous with the tunica media of the pulmonary trunk.[FMA]" [FMA:9535, FMA:FMA] synonym: "Right ventricular myocardium" EXACT [FMA:9535] synonym: "myocardium of right ventricle" EXACT [FMA:9535] xref: FMA:9535 ! Myocardium of right ventricle xref: MA:0002984 ! right ventricle myocardium intersection_of: UBERON:0001083 ! myocardium of ventricle intersection_of: part_of UBERON:0002080 ! right ventricle relationship: continuous_with UBERON:0006563 ! tunica media of pulmonary trunk xref: SCTID:362020004 ! Entire myocardium of right ventricle [Term] id: UBERON:0006575 name: mantle def: "A fold or lobe or pair of lobes of the body wall of a mollusk or brachiopod that in shell-bearing forms lines the shell and bears shell-secreting glands." [BTO:0000825, Wipikedia:Mantle_(mollusc)] synonym: "mantle tissue" RELATED [BTO:0000825] synonym: "pallium" RELATED [Wipikedia:Mantle_(mollusc)] xref: BTO:0000825 ! mantle is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:6447 ! Mollusca [Term] id: UBERON:0006580 name: mantle cavity def: "Within the shell is a fleshy layer of tissue called the mantle; there is a cavity (the mantle cavity) between the mantle and the body wall proper." [BTO:0000826] xref: BTO:0000826 ! mantle cavity intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0006575 ! mantle relationship: part_of UBERON:0006575 ! mantle [Term] id: UBERON:0006581 name: mantle muscle xref: BTO:0000827 ! mantle muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0006575 ! mantle def: "A muscle organ that is part of a mantle." [OBOL:automatic] [Term] id: UBERON:0006595 name: presumptive endoderm xref: AAO:0000471 ! presumptive endoderm xref: ZFA:0000416 ! presumptive endoderm xref: EFO:0003437 ! presumptive endoderm is_a: UBERON:0006598 ! presumptive structure xref: TAO:0000416 ! presumptive endoderm [Term] id: UBERON:0006596 name: presumptive blood xref: AAO:0000468 ! presumptive blood xref: ZFA:0000568 ! presumptive blood xref: EFO:0003439 ! presumptive blood is_a: UBERON:0006598 ! presumptive structure xref: TAO:0000568 ! presumptive blood [Term] id: UBERON:0006598 ! presumptive structure name: presumptive structure synonym: "presumptive structures" EXACT [ZFA:0001116] xref: AAO:0000479 ! presumptive structure xref: ZFA:0001116 ! presumptive structure is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo xref: TAO:0001116 ! presumptive structure [Term] id: UBERON:0006599 name: presumptive hypochord xref: AAO:0000474 ! presumptive hypochord xref: ZFA:0001217 ! presumptive hypochord xref: EFO:0003453 ! presumptive hypochord is_a: UBERON:0006598 ! presumptive structure xref: TAO:0001217 ! presumptive hypochord [Term] id: UBERON:0006600 name: presumptive enteric nervous system xref: AAO:0000472 ! presumptive enteric nervous system xref: ZFA:0001334 ! presumptive enteric nervous system xref: EFO:0003462 ! presumptive enteric nervous system is_a: UBERON:0006598 ! presumptive structure relationship: develops_from UBERON:0005428 {source="NBK10065"} ! vagal neural crest xref: TAO:0001334 ! presumptive enteric nervous system [Term] id: UBERON:0006601 name: presumptive ectoderm comment: Editors note: requires review. ZFA def: Presumptive structure at the animal poll of the blastula that will develop into ectoderm via the epiblast. Determined by fate mapping synonym: "presumptive epidermis" RELATED [ZFA:0001376] xref: AAO:0000470 ! presumptive ectoderm xref: ZFA:0001376 ! presumptive ectoderm xref: EFO:0003466 ! presumptive ectoderm is_a: UBERON:0006598 ! presumptive structure xref: XAO:0004132 ! presumptive ectoderm xref: TAO:0001376 ! presumptive ectoderm [Term] id: UBERON:0006603 name: presumptive mesoderm comment: Editors note: requires review xref: AAO:0000476 ! presumptive mesoderm xref: ZFA:0001377 ! presumptive mesoderm xref: EFO:0003467 ! presumptive mesoderm is_a: UBERON:0006598 ! presumptive structure xref: TAO:0001377 ! presumptive mesoderm [Term] id: UBERON:0006604 name: lamina orbitonasalis def: "Cranial cartilage which is bilaterally paired and develops as a dorsal plate-like projection of the anterolateral ethmoid plate, which are oriented perpendicular to the ethmoid plate. It fuses dorsally to the taenia marginalis anterior, and it joins the ethmoid cartilage medially." [ZFA:0001503] synonym: "laminas orbitonasalis" EXACT [ZFA:0001503] xref: AAO:0000262 ! lamina orbitonasalis xref: ZFA:0001503 ! lamina orbitonasalis is_a: UBERON:0003932 ! cartilaginous elemenet of chondrocranium relationship: part_of UBERON:0001703 ! neurocranium xref: TAO:0001503 ! lamina orbitonasalis property_value: external_definition "In the larva, structure that is fused to the wall of the braincase, lateral to the olfactory foramen, and separates the nasal capsule and orbit. In the adult frog it constitutes the ventral part of postnasal wall.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000262", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0006605 name: tectum synoticum def: "Unpaired thin dorsal sheet of cartilage that partially covers the posterior chondrocranium." [ZFA:0001506] comment: AAO def - "Roof between frontoparietal foramen and otic capsules, confluent with taenia tecti marginales." [AAO:0010129]. In TAO/ZFA this gives rise to supraoccipital and sphenotic // posterior tectum synoticum in humans - a skull roof element of the chondrocranium - temporarily exists in the territory of the interparietal during fetal life, and may be resposible for the sutura mendosa [PMC1259625] xref: ZFA:0001506 ! tectum synoticum is_a: UBERON:0003932 {source="ZFA"} ! cartilage element of chondrocranium relationship: part_of UBERON:0001703 {source="ZFA"} ! neurocranium xref: AAO:0010129 ! tectum synoticum xref: TAO:0001506 ! tectum synoticum property_value: external_definition "Roof between frontoparietal foramen and otic capsules, confluent with taenia tecti marginales.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010129", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010129", date_retrieved="2012-06-20"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of otic and occipital (AAO:0000993)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010129", date_retrieved="2012-06-20"} [Term] id: UBERON:0006632 name: musculo-phrenic artery synonym: "musculophrenic artery" EXACT [FMA:10645] xref: FMA:10645 ! musculophrenic artery xref: EMAPA:19215 ! musculo-phrenic artery is_a: UBERON:0004573 ! systemic artery relationship: branch_of UBERON:0002456 ! internal thoracic artery relationship: part_of UBERON:0002456 ! internal thoracic artery xref: SCTID:244242003 ! Entire musculophrenic artery [Term] id: UBERON:0006634 name: lingual vein def: "The lingual veins begin on the dorsum, sides, and under surface of the tongue, and, passing backward along the course of the lingual artery, end in the internal jugular vein. The vena comitans of the hypoglossal nerve (ranine vein), a branch of considerable size, begins below the tip of the tongue, and may join the lingual; generally, however, it passes backward on the Hyoglossus, and joins the common facial." [Wikipedia:Lingual_veins] synonym: "deep lingual veins" RELATED [Wikipedia:Lingual_veins] synonym: "lingual vein" RELATED [Wikipedia:Lingual_veins] synonym: "ranine" RELATED [Wikipedia:Lingual_veins] synonym: "ranine vein" RELATED [Wikipedia:Lingual_veins] xref: FMA:14326 ! Lingual vein xref: EMAPA:19312 ! lingual vein is_a: UBERON:0001638 ! vein xref: AAO:0010514 ! lingual vein xref: SCTID:181375007 ! Entire lingual vein synonym: "vena lingualis" RELATED LATIN [Wikipedia:Lingual_veins] xref: http://upload.wikimedia.org/wikipedia/commons/7/7a/Gray559.png property_value: external_definition "Vein which collects blood from the tongue and drains into the external jugular vein.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010514", date_retrieved="2012-06-20", source="AAO:BJB"} [Term] id: UBERON:0006635 ! anterior abdominal wall name: anterior abdominal wall synonym: "ventral abdominal wall" EXACT [] xref: FMA:14627 ! Anterior abdominal wall xref: EMAPA:17744 ! anterior abdominal wall xref: VHOG:0000764 ! anterior abdominal wall xref: EHDAA:5976 ! anterior abdominal wall is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0003697 ! abdominal wall xref: SCTID:362696003 ! Entire anterior abdominal wall [Term] id: UBERON:0006636 name: lumbar artery def: "The lumbar arteries are in series with the intercostals. They are usually four in number on either side, and arise from the back of the aorta, opposite the bodies of the upper four lumbar vertebrC&. A fifth pair, small in size, is occasionally present: they arise from the middle sacral artery. They run lateralward and backward on the bodies of the lumbar vertebrC&, behind the sympathetic trunk, to the intervals between the adjacent transverse processes, and are then continued into the abdominal wall. The arteries of the right side pass behind the inferior vena cava, and the upper two on each side run behind the corresponding crus of the diaphragm. The arteries of both sides pass beneath the tendinous arches which give origin to the Psoas major, and are then continued behind this muscle and the lumbar plexus. They now cross the Quadratus lumborum, the upper three arteries running behind, the last usually in front of the muscle. At the lateral border of the Quadratus lumborum they pierce the posterior aponeurosis of the Transversus abdominis and are carried forward between this muscle and the Obliquus internus. They anastomose with the lower intercostal, the subcostal, the iliolumbar, the deep iliac circumflex, and the inferior epigastric arteries." [Wikipedia:Lumbar_arteries] synonym: "arteria lumbalis" RELATED [Wikipedia:Lumbar_arteries] synonym: "lumbar artery" RELATED [Wikipedia:Lumbar_arteries] synonym: "Lumbar arterial tree" EXACT [FMA:14735] xref: FMA:14735 ! Lumbar artery xref: EMAPA:19096 ! lumbar artery is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0001516 {source="Wikipedia"} ! abdominal aorta xref: ncithesaurus:Lumbar_Artery ! Lumbar Artery xref: SCTID:244285007 ! Entire lumbar artery synonym: "arteriae lumbales" RELATED LATIN [Wikipedia:Lumbar_arteries] xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png xref: UMLS:C0226408 [Term] id: UBERON:0006637 name: coeliac trunk def: "The celiac artery, also known as the celiac trunk, is the first major branch of the abdominal aorta. Branching from the aorta 'anterior to the upper part of T12' vertebra in humans, it is one of three anterior/ midline branches of the abdominal aorta." [Wikipedia:Celiac_artery] synonym: "arteria celiaca" RELATED [Wikipedia:Celiac_artery] synonym: "celiac axis" RELATED [Wikipedia:Celiac_artery] synonym: "celiac trunk" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac axis" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunck" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunk" RELATED [Wikipedia:Celiac_artery] synonym: "truncus coeliacus" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunk" EXACT [FMA:14812] synonym: "coeliaco-mesenteric trunk" EXACT [FMA:14812] synonym: "Haller's tripus" EXACT [FMA:14812] xref: FMA:14812 ! Celiac trunk xref: EMAPA:19212 ! coeliac trunk is_a: UBERON:0000063 ! organ segment relationship: part_of UBERON:0001640 ! celiac artery xref: galen:CeliacTrunk xref: EHDAA2:0004519 ! coeliac trunk (also: UBERON:0001640 'celiac artery') [Term] id: UBERON:0006638 name: median umbilical ligament def: "The median umbilical ligament is a structure in human anatomy. It is a shrivelled piece of tissue that represents the remnant of the embryonic urachus. It extends from the apex of the bladder to the umbilicus, on the deep surface of the anterior abdominal wall. It is unpaired. It is covered by the median umbilical fold Lateral to this structure are the medial umbilical ligament (which is a different structure, not to be confused) and the lateral umbilical ligament." [Wikipedia:Median_umbilical_ligament] synonym: "median umbilical fold" RELATED [Wikipedia:Median_umbilical_ligament] synonym: "middle umbilical ligament" RELATED [Wikipedia:Median_umbilical_ligament] xref: FMA:16568 ! Median umbilical ligament xref: EMAPA:29637 ! median umbilical ligament is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001008 ! urinary system relationship: develops_from UBERON:0002068 ! urachus xref: SCTID:89583000 ! Middle umbilical ligament synonym: "ligamentum umbilicale medianum" RELATED LATIN [Wikipedia:Median_umbilical_ligament] xref: http://upload.wikimedia.org/wikipedia/commons/e/ef/Gray1036.png [Term] id: UBERON:0006639 name: crus penis def: "For their anterior three-fourths the corpora cavernosa penis lie in intimate apposition with one another, but behind they diverge in the form of two tapering processes, known as the crura, which are firmly connected to the ischial rami. Traced from behind forward, each crus begins by a blunt-pointed process in front of the tuberosity of the ischium, along the perineal surface of the conjoined (ischiopubic) ramus. Just before it meets its fellow it presents a slight enlargement, named by Georg Ludwig Kobelt (1804-1857) the bulb of the corpus cavernosum penis. Beyond this point the crus undergoes a constriction and merges into the corpus cavernosum proper, which retains a uniform diameter to its anterior end." [Wikipedia:Crus_of_penis] synonym: "crus of penis" EXACT [FMA:18248] synonym: "crura of penis" RELATED [Wikipedia:Crus_of_penis] xref: FMA:18248 ! Crus penis xref: EMAPA:19294 ! crus penis is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0004713 ! corpus cavernosum penis xref: SCTID:362270006 ! Entire crus penis synonym: "crus penis" RELATED LATIN [Wikipedia:Crus_of_penis] xref: http://upload.wikimedia.org/wikipedia/commons/e/ef/Gray1154.png [Term] id: UBERON:0006640 name: crus of clitoris def: "The clitoral crura are an internal portion of the clitoris. A single one is called a clitoral crus. They are shaped like an inverted \"V\" with the vertex of the \"V\" connecting to the clitoral body. They are near the vestibular bulbs, also known as the clitoral bulbs. They are to the left and right of the urethra, urethral sponge, and vagina and extend back toward the pubic bone. The clitoral crura contain muscles called the ischiocavernosi. \"Crus\" basically translates as \"leg\", thus \"crura\" as \"legs\". Each clitoral crus connects to the rami of the pubis and the ischium. The crura, like the rest of the clitoris, are composed of two corpus cavernosa muscles, which are made up of erectile tissue." [Wikipedia:Crus_of_clitoris] synonym: "crura of clitoris" RELATED [Wikipedia:Clitoral_crura] synonym: "crus clitoridis" RELATED [Wikipedia:Clitoral_crura] synonym: "crus of clitoris" RELATED [Wikipedia:Clitoral_crura] synonym: "Clitoris crus" EXACT [FMA:20175] xref: FMA:20175 ! Crus of clitoris xref: EMAPA:19169 ! crus of clitoris of genital tubercle of female xref: EMAPA:30821 ! crus of clitoris of clitoris is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0006608 ! corpus cavernosum clitoridis xref: SCTID:279860002 ! Entire crus of clitoris xref: http://upload.wikimedia.org/wikipedia/commons/8/8c/Clitoris_inner_anatomy.gif [Term] id: UBERON:0006641 name: appendix epididymis def: "On the head of the epididymis is a small stalked appendage (sometimes duplicated). It is named the appendix of the epididymis (or pedunculated hydatid), and is usually regarded as a detached efferent duct. This structure is derived from the Wolffian duct as opposed to the appendix testis which is derived from the mullerian duct remnant." [Wikipedia:Appendix_of_epididymidis] synonym: "appendix epididymis" RELATED [Wikipedia:Appendix_of_epididymidis] synonym: "appendix of the epididymis" RELATED [Wikipedia:Appendix_of_epididymidis] synonym: "epididymal appendix" EXACT [FMA:18268] synonym: "epididymis appendix" EXACT [FMA:18268] xref: FMA:18268 ! Appendix of epididymis xref: EMAPA:19086 ! appendix epididymis is_a: UBERON:0005160 ! vestigial structure relationship: part_of UBERON:0001301 ! epididymis relationship: develops_from UBERON:0003074 ! wolffian duct synonym: "appendix epididymidis" RELATED LATIN [Wikipedia:Appendix_of_epididymidis] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray1148.png synonym: "appendix of epididymis" EXACT [FMA:18268] [Term] id: UBERON:0006642 name: muscle layer of oviduct synonym: "muscle layer of fallopian tube" EXACT [FMA:18318] synonym: "muscle layer of oviduct" EXACT [FMA:18318] synonym: "muscular coat of uterine tube" EXACT [FMA:18318] synonym: "muscular layer of uterine tube" EXACT [FMA:18318] synonym: "muscularis of uterine tube" EXACT [FMA:18318] synonym: "tunica muscularis (Tuba uterina)" EXACT [FMA:18318] synonym: "uterine tubal muscularis" EXACT [FMA:18318] xref: FMA:18318 ! Muscle layer of uterine tube xref: EMAPA:29046 ! muscle layer of oviduct intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0003889 ! fallopian tube synonym: "tunica muscularis tubae uterinae" EXACT LATIN [FMA:TA, FMA:18318] xref: SCTID:259488000 ! Entire uterine tubal muscularis synonym: "muscle layer of uterine tube" EXACT [FMA:18318] def: "A muscle layer that is part of a fallopian tube." [OBOL:automatic] [Term] id: UBERON:0006610 ! tunica albuginea name: tunica albuginea def: "White covering over one of: penis, testicles or ovaries." [Wikipedia:Tunica_albuginea] is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0003133 ! reproductive organ [Term] id: UBERON:0006643 name: tunica albuginea of testis def: "The Tunica Albuginea is the fibrous covering of the testis. It is a dense blue-white membrane, composed of bundles of white fibrous tissue which interlace in every direction. It is covered by the tunica vaginalis, except at the points of attachment of the epididymis to the testis, and along its posterior border, where the spermatic vessels enter the gland. It is applied to the tunica vasculosa over the glandular substance of the testis, and, at its posterior border, is reflected into the interior of the gland, forming an incomplete vertical septum, called the mediastinum testis (corpus Highmori)." [Wikipedia:Tunica_albuginea_of_testis_%28ovaries%29_%28penis%29_of_testis] synonym: "tunica albuginea %28testicles%29" RELATED [Wikipedia:Tunica_albuginea_of_testis] synonym: "tunica albuginea (testis)" EXACT [FMA:19843] synonym: "tunica albuginea" BROAD [ncithesaurus:Tunica_Albuginea, VHOG:0000801, EHDAA2:0002096] xref: FMA:19843 ! Tunica albuginea of testis xref: EMAPA:19289 ! tunica albuginea of testis xref: EHDAA2:0002096 ! tunica albuginea xref: EHDAA:9388 ! tunica albuginea xref: VHOG:0000801 ! tunica albuginea xref: ncithesaurus:Tunica_Albuginea ! Tunica Albuginea is_a: UBERON:0007475 {source="EHDAA2"} ! matrix-based tissue intersection_of: UBERON:0006610 ! tunica albuginea intersection_of: part_of UBERON:0000473 ! testis relationship: develops_from UBERON:0003312 {source="EHDAA2"} ! mesenchyme of testis xref: SCTID:279604006 ! Entire tunica albuginea of testis synonym: "tunica albuginea testis" RELATED LATIN [Wikipedia:Tunica_albuginea_of_testis] property_value: external_definition "The layer of connective tissue covering the testicles. [Wikipedia_(15/09/09)][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0000801", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} property_value: homology_notes "The tunica albuginea testis is the major component of the capsule of mammalian testes. (...) Our results from studying the mole provide evidence that the spatio-temporal pattern of testis development is not perfectly conserved in mammals, since we found differences with respect to the mouse testis organogenesis. This fact is even more significant when we consider that, apart from the mouse, the mole is probably the one of the best-known mammalian species in terms of the genetic control of testis development, implying that more peculiarities would be found if more species were investigated.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000801", ontology="VHOG", source="DOI:10.1387/ijdb.072470fc The spatio-temporal pattern of testis organogenesis in mammals - insights from the mole. The International Journal of Developmental Biology (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0227999 [Term] id: UBERON:0006644 name: tunica albuginea of ovary def: "The tunica albuginea is the fibrous envelope of the corpora cavernosa penis. It is comprised of approximately 5% elastin, an extensible tissue that is primarily made up of the amino acids glycine, valine, alanine, and proline. The majority of the remaining tissue is comprised of collagen, which is made up of lysine, proline, glycine, alanine, and other amino acids . The tunica albuginea is directly involved in maintaining an erection; that is due to Buck's fascia constricting the deep dorsal vein of the penis, preventing blood from leaving and thus sustaining the erect state. The trabeculC& of the tunica albuginea are more delicate, nearly uniform in size, and the meshes between them smaller than in the corpora cavernosa penis: their long diameters, for the most part, corresponding with that of the penis. The external envelope or outer coat of the corpus spongiosum is formed partly of unstriped muscular fibers, and a layer of the same tissue immediately surrounds the canal of the urethra." [Wikipedia:Tunica_albuginea_of_testis_%28ovaries%29_%28penis%29_%28penis%29] xref: FMA:18630 ! Tunica albuginea of ovary xref: EMAPA:30522 ! tunica albuginea of ovary intersection_of: UBERON:0006610 ! tunica albuginea intersection_of: part_of UBERON:0000992 ! female gonad relationship: part_of UBERON:0001307 ! capsule of ovary xref: SCTID:258409003 ! Entire tunica albuginea of ovary synonym: "tunica albuginea corporum cavernosorum, tunica albuginea corporis spongiosi" RELATED LATIN [Wikipedia:Tunica_albuginea_%28penis%29] [Term] id: UBERON:0006645 name: adventitia of epididymis synonym: "epididymis adventitia" EXACT [FMA:19136] xref: FMA:19136 ! Adventitia of epididymis xref: EMAPA:30443 ! adventitia of epididymis intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0001301 ! epididymis def: "An adventitia that is part of a epididymis." [OBOL:automatic] [Term] id: UBERON:0006646 name: muscle layer of epididymis xref: FMA:19149 ! Muscle layer of epididymis xref: EMAPA:30447 ! muscle layer of epididymis of epididymis intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0001301 ! epididymis def: "A muscle layer that is part of a epididymis." [OBOL:automatic] [Term] id: UBERON:0006647 name: adventitia of ductus deferens synonym: "adventitia of ductus deferens" EXACT [FMA:19238] synonym: "adventitia of vas deferens" EXACT [FMA:19238] synonym: "deferent ductal adventitia" EXACT [FMA:19238] synonym: "tunica adventitia (ductus deferens)" EXACT [FMA:19238] xref: FMA:19238 ! Adventitia of deferent duct xref: EMAPA:29767 ! adventitia of ductus deferens intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0001000 ! vas deferens synonym: "tunica adventitia ductus deferentis" EXACT LATIN [FMA:TA, FMA:19238] xref: SCTID:299803005 ! Entire adventitia of vas deferens synonym: "adventitia of deferent duct" EXACT [FMA:19238] def: "An adventitia that is part of a vas deferens." [OBOL:automatic] [Term] id: UBERON:0006648 name: adventitia of seminal vesicle synonym: "adventitia of seminal gland" EXACT [FMA:19403] synonym: "seminal vesicle adventitia" EXACT [FMA:19403] synonym: "tunica adventitia (vesicula seminalis)" EXACT [FMA:19403] xref: FMA:19403 ! Adventitia of seminal vesicle xref: EMAPA:29775 ! adventitia of seminal vesicle intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0000998 ! seminal vesicle synonym: "tunica adventitia glandulae vesiculosae" EXACT LATIN [FMA:TA, FMA:19403] xref: SCTID:252406002 ! Entire adventitia of seminal vesicle def: "An adventitia that is part of a seminal vesicle." [OBOL:automatic] [Term] id: UBERON:0012504 name: adventitia of esophagus synonym: "adventitia of oesophagus" EXACT [FMA:63006] synonym: "adventitious layer of esophagus" EXACT [FMA:63006] synonym: "esophageal adventitia" EXACT [FMA:63006] synonym: "esophagus adventitia" EXACT [FMA:63006] synonym: "tunica adventitia (esophagus)" EXACT [FMA:63006] synonym: "tunica adventitia oesophageae" EXACT [FMA:TA] synonym: "esophageal adventitia" EXACT [SCTID:85950006] intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0001043 ! esophagus xref: FMA:63006 ! adventitia of esophagus xref: SCTID:85950006 ! Esophageal adventitia [Term] id: UBERON:0006649 name: suspensory ligament of ovary def: "A fold of peritoneum that extends out from the ovary to the wall of the pelvis. " [Wikipedia:Cooper%27s_ligaments_of_penis_of_ovary] comment: Some sources consider it a part of the broad ligament of uterus[2] while other sources just consider it a "termination" of the ligament.[3] synonym: "infundibulopelvic fold" EXACT [FMA:19822] synonym: "infundibulopelvic ligament" EXACT [FMA:19822] xref: FMA:19822 ! Suspensory ligament of ovary xref: EMAPA:19085 ! suspensory ligament of ovary is_a: UBERON:0008841 {source="Obol"} ! suspensory ligament is_a: UBERON:0002095 {source="FMA"} ! mesentery relationship: develops_from UBERON:0000080 {source="Wikipedia"} ! mesonephros relationship: develops_from UBERON:0003074 {source="Wikipedia"} ! mesonephric duct relationship: attaches_to UBERON:0000992 ! female gonad disjoint_from: UBERON:0008847 ! ovarian ligament xref: SCTID:279917007 ! Entire suspensory ligament of ovary [Term] id: UBERON:0010391 ! parametrium name: parametrium def: "In women, the supravaginal portion of the cervix is separated in front from the bladder by fibrous tissue, the parametrium, which extends also on to its sides and laterally between the layers of the broad ligaments. The uterine artery and ovarian ligament are located in the parametrium. Inflammation causes Parametritis." [Wikipedia:Parametrium] comment: subserous coat of the uterus laterally between the layers of the broad ligament[MP] - todo - check relationships is_a: UBERON:0002095 {source="FMA"} ! mesentery xref: FMA:77061 ! parametrium xref: SCTID:280455005 ! Entire parametrium xref: ncithesaurus:Parametrium ! parametrium xref: UMLS:C0227822 [Term] id: UBERON:0008847 ! ovarian ligament name: ovarian ligament def: "a fibrous ligament that connects the ovary to the lateral surface of the uterus." [Wikipedia:Ovarian_ligament] comment: The ligament runs in the broad ligament of the uterus, which is a fold of peritoneum rather than a fibrous ligament. Specifically, it is located in the parametrium synonym: "ligament of ovary" EXACT [FMA:55422] synonym: "ligamentum ovarii proprium" EXACT LATIN [FMA:TA] synonym: "proper ovarian ligament" EXACT [FMA:55422] is_a: UBERON:0008845 {source="FMA"} ! nonskeletal ligament relationship: attaches_to UBERON:0000992 ! female gonad relationship: attaches_to UBERON:0000995 ! uterus xref: FMA:55422 ! ovarian ligament relationship: develops_from UBERON:0004346 {source="Wikipedia"} ! gubernaculum xref: SCTID:279915004 ! Ligament of ovary [Term] id: UBERON:0012331 name: mesosalpinx def: "The mesosalpinx is part of the lining of the abdominal cavity in higher vertebrates, specifically the portion of the broad ligament that stretches from the uterine tube to the level of the ovary." [Wikipedia:Mesosalpinx] is_a: UBERON:0002095 ! mesentery relationship: part_of UBERON:0012332 ! broad ligament of uterus xref: FMA:19808 ! mesosalpinx xref: SCTID:279900000 ! Entire mesosalpinx [Term] id: UBERON:0012332 name: broad ligament of uterus def: "A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis[MESH]." [MESH:A02.513.170, Wikipedia:Broad_ligament_of_the_uterus] synonym: "broad ligament" RELATED [MESH:A02.513.170] synonym: "broad uterine ligament" EXACT [FMA:16516] is_a: UBERON:0000211 {source="MESH"} ! ligament relationship: part_of UBERON:0002095 ! mesentery xref: FMA:16516 ! broad ligament of uterus xref: ncithesaurus:Broad_Ligament ! broad ligament xref: MESH:A02.513.170 ! broad ligament xref: ncithesaurus:Broad_Ligament ! broad ligament xref: SCTID:362723009 ! Entire broad ligament xref: UMLS:C0006205 [Term] id: UBERON:0001342 name: mesovarium def: "The mesentery that suspends the ovary from the dorsal wall of the coelom[VHOG]." [Wikipedia:Mesovarium, VHOG:0001566] synonym: "mesovarian ligament" RELATED [] subset: uberon_slim subset: vertebrate_core xref: FMA:19815 ! Mesovarium xref: TAO:0000333 ! mesovarium xref: ZFA:0000333 ! mesovarium xref: http://upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Gray1111.png/200px-Gray1111.png xref: EMAPA:17961 ! mesovarium is_a: UBERON:0002095 ! mesentery relationship: part_of UBERON:0000992 ! female gonad relationship: part_of UBERON:0002095 ! mesentery relationship: part_of UBERON:0012332 ! broad ligament of uterus xref: VHOG:0001566 ! mesovarium xref: AAO:0010531 ! mesovarium xref: SCTID:279914000 ! Entire mesovarium xref: ncithesaurus:Mesovarian_Ligament ! mesovarium xref: http://upload.wikimedia.org/wikipedia/commons/e/e7/Gray1111.png property_value: external_definition "Anatomical structure consisting of a membrane which suspends the ovaries from the mesial side of the kidney.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010531", date_retrieved="2012-06-20", source="AAO:BJB"} property_value: external_definition "The mesentery that suspends the ovary from the dorsal wall of the coelom. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.560, see_Kardong_KV][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001566", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0230310 [Term] id: UBERON:0012333 name: ovarian bursa def: "a pouch formed by the mesosalpinx and the mesovarium that encloses the infundibulum of the uterine tube and the ovary" [http://medical-dictionary.thefreedictionary.com/ovarian] comment: Ovaries of some animals are surrounded by a thin membranous sac, the bursa, and are isolated from the peritoneal cavity. The bursa is continuous with the orifice of the oviduct. The bursa is not continuous in other mammals (eg., farm animals and human beings); ovaries of these species can be exposed within the abdomen, and thus ectopic pregnancy is possible[http://www.uwyo.edu/wjm/repro/femanat.htm] xref: SCTID:250080006 ! Entire ovarian bursa is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002358 ! peritoneum [Term] id: UBERON:0006650 name: tunica vaginalis testis def: "The tunica vaginalis is the serous covering of the testis. It is a pouch of serous membrane, derived from the saccus vaginalis of the peritoneum, which in the fetus preceded the descent of the testis from the abdomen into the scrotum. After its descent, that portion of the pouch which extends from the abdominal inguinal ring to near the upper part of the gland becomes obliterated; the lower portion remains as a shut sac, which invests the surface of the testis, and is reflected on to the internal surface of the scrotum; hence it may be described as consisting of a visceral and a parietal lamina." [Wikipedia:Tunica_vaginalis] comment: We follow FMA is classifying as membranous layer - but this does not account for relationship to mesolthelium (subclass or has part?). The FMA also has 'sac of tunica vaginalis', which is a serous sac synonym: "lamina parietalis" RELATED [Wikipedia:Tunica_vaginalis] synonym: "lamina visceralis" RELATED [Wikipedia:Tunica_vaginalis] synonym: "tunica vaginalis testis" RELATED [Wikipedia:Tunica_vaginalis] synonym: "tunica vaginalis testis" RELATED LATIN [Wikipedia:Tunica_vaginalis] synonym: "tunica vaginalis of testis" EXACT [FMA:19844] synonym: "tunica vaginalis" RELATED [] xref: FMA:19844 ! Tunica vaginalis of testis xref: FMA:15863 ! Tunica vaginalis (membrane) xref: EMAPA:19179 ! tunica vaginalis testis xref: SCTID:362281009 ! Entire tunica vaginalis is_a: UBERON:0000158 {source="FMA"} ! membranous layer relationship: part_of UBERON:0000473 {source="EMAPA"} ! testis relationship: develops_from UBERON:0005344 {source="Wikipedia"} ! peritoneal vaginal process relationship: has_part UBERON:0001136 ! mesothelium xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray1148.png [Term] id: UBERON:0013247 ! male paramesonephric duct name: male paramesonephric duct synonym: "degenerating mesonephric portion of male paramesonephric duct" RELATED [EMAPA:29161] intersection_of: UBERON:0003914 ! epithelial tube intersection_of: develops_from UBERON:0003890 ! Mullerian duct intersection_of: part_of UBERON:0000079 ! male reproductive system relationship: develops_from UBERON:0003890 {source="EHDAA2"} ! Mullerian duct relationship: part_of UBERON:0000079 {source="EHDAA2"} ! male reproductive system xref: EHDAA2:0001052 ! male paramesonephric duct xref: EMAPA:29161 ! degenerating mesonephric portion of male paramesonephric duct [Term] id: UBERON:0006651 name: appendix testis def: "The appendix testis is a vestigial remnant of the Mullerian duct, present on the upper pole of the testis and attached to the tunica vaginalis. It is present about 90% of the time." [Wikipedia:Appendix_of_testis] comment: Editor notes: the label hydatid of morgagni is ambiguous w.r.t male vs female. The ncita structure 'hydatic of morgani[sic]' is male and thus belongs here. See also 'vesicular appendage of epoophoron' synonym: "appendices testis" RELATED PLURAL [Wikipedia:Appendix_of_testis] synonym: "appendix of the testis" RELATED [Wikipedia:Appendix_of_testis] synonym: "appendix testis" RELATED [Wikipedia:Appendix_of_testis] synonym: "testis appendix" EXACT [FMA:19846] synonym: "hydatid of Morgagni" BROAD [http://medical-dictionary.thefreedictionary.com/Hydatid+of+Morgagni] synonym: "hydatid of Morgani" BROAD [] synonym: "appendix vesiculosus" RELATED [FMA:18696] synonym: "hydatid of morgagni" BROAD [FMA:18696] xref: FMA:19846 ! Appendix of testis xref: EMAPA:19087 ! appendix testis xref: ncithesaurus:Hydatid_of_Morgani ! hydatid of morgani is_a: UBERON:0006590 ! vestigial embryonic structure relationship: develops_from UBERON:0013247 {source="cjm"} ! male paramesonephric duct relationship: part_of UBERON:0000079 {source="EMAPA"} ! male reproductive system relationship: attaches_to UBERON:0006650 {source="Wikipedia"} ! tunica vaginalis testis xref: SCTID:279601003 ! Appendix of testis synonym: "appendix testis" RELATED LATIN [Wikipedia:Appendix_of_testis] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray1148.png synonym: "appendix of testis" EXACT [FMA:19846] property_value: external_definition "a cystlike remnant of the müllerian duct on the upper end of the testis; corresponding female structure: one of the small pedunculated structures attached to the uterine tubes near their fimbriated end; remnants of the mesonephric ducts[http://medical-dictionary.thefreedictionary.com/]." xsd:string {source="http://medical-dictionary.thefreedictionary.com/Hydatid+of+Morgagni"} xref: UMLS:C1512521 [Term] id: UBERON:0013250 name: vesicular appendage of epoophoron def: "In connection with the fimbriae of the uterine tube, or with the broad ligament close to them, there are frequently one or more small pedunculated vesicles. These are termed the vesicular appendages of the epoophoron." [Wikipedia:Vesicular_appendages_of_epoophoron] synonym: "appendices vesiculosae" RELATED [Wikipedia:Vesicular_appendages_of_epoophoron] synonym: "appendix vesiculosus" EXACT [FMA:18696] synonym: "hydatid of Morgagni" BROAD [FMA:18696] synonym: "hydatid of Morgagni" BROAD [Wikipedia:Hydatid_of_Morgagni] synonym: "vesicular appendage of epoophoron" RELATED [FMA:18696] synonym: "vesicular appendage of epoöphoron" RELATED [] synonym: "appendage of epoophoron" RELATED [] synonym: "appendage of epoöphoron" RELATED [] synonym: "appendices vesiculosae epoophori" RELATED LATIN [] is_a: UBERON:0006590 {source="FMA"} ! vestigial embryonic structure relationship: develops_from UBERON:0003890 {source="Wikipedia", notes="cranial end"} ! Mullerian duct relationship: part_of UBERON:0000474 ! female reproductive system xref: FMA:18696 ! vesicular appendage of epoophoron property_value: external_definition "one of the small pedunculated structures attached to the uterine tubes near their fimbriated end; remnants of the mesonephric ducts[http://medical-dictionary.thefreedictionary.com/]." xsd:string {source="http://medical-dictionary.thefreedictionary.com/Hydatid+of+Morgagni"} [Term] id: UBERON:0011199 name: prostatic utricle def: "a small indentation located in the prostatic urethra, at the apex of the urethral crest, on the seminal colliculus (verumontanum), laterally flanked by openings of the ejaculatory ducts. It is also known as the vagina masculina or (in older literature) vesicula prostatica. It is often described as \"blind,\" meaning that it is a duct that does not lead to any other structures. It can sometimes be enlarged." [Wikipedia:Prostatic_utricle] comment: Editor notes: add df relations. Check mesopnephric duct synonym: "uterus masculinus" RELATED [Wikipedia:Prostatic_utricle] synonym: "utriculus prostaticus" RELATED [Wikipedia:Prostatic_utricle] synonym: "vagina masculina" RELATED [Wikipedia:Prostatic_utricle] synonym: "vesicula prostatica" RELATED [Wikipedia:Prostatic_utricle] synonym: "sinus pocularis" EXACT [FMA:19702] synonym: "uterus masculinus" EXACT [FMA:19702] synonym: "utricle of prostate" EXACT [FMA:19702] synonym: "utriculus of prostate" EXACT [FMA:19702] synonym: "vagina masculina" EXACT [FMA:19702] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001335 {source="FMA"} ! prostatic urethra xref: FMA:19702 ! prostatic utricle xref: ncithesaurus:Prostatic_Utricle ! prostatic utricle xref: SCTID:197909004 ! Entire prostatic utricle xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray1153.png xref: UMLS:C0227736 [Term] id: UBERON:0013262 name: remnnant of ductus deferens def: "remnant in a female of the portion of the embryonic mesonephric duct that develops into the ductus deferens in males." [http://www.medilexicon.com/medicaldictionary.php?t=98549] synonym: "ductus deferens vestigialis" EXACT LATIN [] synonym: "ductus deferens vestige" EXACT [FMA:76609] synonym: "vestige of ductus deferens" EXACT [FMA:76609] is_a: UBERON:0006590 {source="FMA"} ! vestigial embryonic structure relationship: develops_from UBERON:0003890 {source="Wikipedia"} ! Mullerian duct relationship: part_of UBERON:0000474 ! female reproductive system xref: FMA:76609 ! Vestige of ductus deferens [Term] id: UBERON:0013277 name: remnant of processus vaginalis def: "incompletely obliterated remnants of the vaginal process of the peritoneum remaining in the spermatic cord." [http://www.medilexicon.com/medicaldictionary.php?t=98550] synonym: "processus vaginalis vestige" EXACT [FMA:77300] synonym: "vestige of processus vaginalis" EXACT [FMA:77300] is_a: UBERON:0006590 {source="FMA"} ! vestigial embryonic structure relationship: part_of UBERON:0005352 ! spermatic cord relationship: develops_from UBERON:0005344 ! peritoneal vaginal process xref: FMA:77300 ! vestige of processus vaginalis [Term] id: UBERON:0013278 name: canal of Nuck def: "A patent pouch of peritoneum extending into the labia majora of women. It is analogous to the processus vaginalis in males. The pouch accompanies the gubernaculum during development of the urinary and reproductive organs, more specifically during the descent of the ovaries, and normally obliterates." [Wikipedia:Canal_of_Nuck] synonym: "processus vaginalis peritonei femininus" RELATED LATIN [Wikipedia:Canal_of_Nuck] synonym: "persistent processus vaginalis" RELATED [MP:0009217] synonym: "canal of nuck" RELATED [Wikipedia:Canal_of_Nuck] synonym: "nuck%27s canal" RELATED [Wikipedia:Canal_of_Nuck] is_a: UBERON:0006590 {source="cjm"} ! vestigial embryonic structure relationship: develops_from UBERON:0005344 ! peritoneal vaginal process relationship: part_of UBERON:0000474 ! female reproductive system [Term] id: UBERON:0006652 name: muscular layer of vagina synonym: "muscular coat of vagina" EXACT [FMA:19976] synonym: "tunica muscularis vaginae" EXACT LATIN [FMA:TA, FMA:19976] synonym: "vaginal muscularis" EXACT [] xref: FMA:19976 ! Muscular layer of vagina xref: EMAPA:30997 ! muscular layer of vagina xref: SCTID:253069005 ! Entire vaginal muscularis intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0000996 ! vagina def: "A muscle tissue that is part of a vagina." [OBOL:automatic] [Term] id: UBERON:0006654 name: perineal body def: "The perineal body (or central tendon of perineum) is a pyramidal fibromuscular mass in the middle line of the perineum at the junction between the urogenital triangle and the anal triangle . It is found in both males and females. In males, it is found between the bulb of penis and the anus; in females, is found between the vagina and anus, and about 1.25 cm in front of the latter. The perineal body is essential for the integrity of the pelvic floor, particularly in females. Its rupture during delivery leads to widening of the gap between the anterior free borders of levator ani muscle of both sides, thus predisposing the woman to prolapse of the uterus, rectum, or even the urinary bladder." [Wikipedia:Perineal_body] synonym: "central tendinous point" RELATED [Wikipedia:Perineal_body] synonym: "central tendinous point of the perineum" RELATED [Wikipedia:Perineal_body] synonym: "central tendon of perineum" RELATED [Wikipedia:Perineal_body] synonym: "central tendon of perineum" EXACT [FMA:20274] xref: FMA:20274 ! Perineal body xref: EMAPA:17892 ! perineal body of hindgut xref: EMAPA:18921 ! perineal body of gut is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002356 ! perineum xref: SCTID:367754000 ! Entire perineal body synonym: "corpus perineale, centrum tendineum perinei" RELATED LATIN [Wikipedia:Perineal_body] xref: http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png [Term] id: UBERON:0006655 name: septum of scrotum synonym: "Scrotal septum" EXACT [FMA:20729] xref: FMA:20729 ! Septum of scrotum xref: EMAPA:29745 ! septum of scrotum is_a: UBERON:0003037 ! septum relationship: part_of UBERON:0001300 ! scrotum xref: SCTID:279591002 ! Entire scrotal septum [Term] id: UBERON:0006656 name: deep dorsal vein of penis xref: FMA:21354 ! Deep dorsal vein of penis xref: EMAPA:19219 ! deep dorsal vein of penis is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0000989 ! penis relationship: tributary_of UBERON:0001317 {source="FMA/obol"} ! internal iliac vein xref: SCTID:55433007 ! Entire deep dorsal vein of penis [Term] id: UBERON:0006657 name: glenoid fossa def: "Anatomical cavity for the proximal articular surface of the proximal limb or fin element with the scapulocoracoid or equivalent structure." [Wikipedia:Glenoid_cavity, PHENOSCAPE:ad] comment: Taxon notes: The glenoid fossa can be associated with the metapterygium in sarcopterygians, or either the meso- or propterygium in basal gnathostomes such as Chondrichthyans[ad]. AO notes: FMA also has classes for the bony parts around the cavity - these may be more useful than the cavity term itself synonym: "glenoid cavity" RELATED [AAO:0000749] synonym: "cavitus glenoidalis" EXACT [FMA:23275] synonym: "glenoid cavity" EXACT [FMA:23275] synonym: "glenoid cavity of scapula" EXACT [FMA:23275] synonym: "cavitas glenoidalis scapulae" EXACT LATIN [FMA:TA, FMA:23275] synonym: "cavitas glenoidalis" RELATED LATIN [Wikipedia:Glenoid_cavity] xref: FMA:23275 ! Glenoid fossa xref: EMAPA:25122 ! glenoid fossa xref: AAO:0000749 ! glenoid fossa is_a: UBERON:0004704 ! bone fossa relationship: adjacent_to UBERON:0001124 {notes="to be revised after scapulocoracoid fixes"} ! pectoral limb scapula xref: ncithesaurus:Glenoid_Fossa ! Glenoid Fossa xref: http://upload.wikimedia.org/wikipedia/commons/e/ec/Gray328.png property_value: external_definition "Cavity for the articulation of the forelimb formed by the scapula, coracoid, and clavicle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000749", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of scapular area (AAO:0000935)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000749", date_retrieved="2012-06-20"} xref: SCTID:181914008 ! Entire glenoid cavity of scapula xref: UMLS:C1261046 [Term] id: UBERON:0010760 name: supraglenoid tubercle def: "The supraglenoid tubercle is a region of the scapula to which the long head of the biceps brachii muscle attaches." [Wikipedia:Supraglenoid_tubercle] synonym: "supraglenoid tuberosity" EXACT [FMA:23263] is_a: UBERON:0005813 {source="FMA"} ! tubercle relationship: part_of UBERON:0006633 ! coracoid process xref: FMA:23263 ! supraglenoid tubercle synonym: "tuberculum supraglenoidale" RELATED LATIN [Wikipedia:Supraglenoid_tubercle] xref: http://upload.wikimedia.org/wikipedia/commons/a/a6/Gray205_left_scapula_lateral_view.png [Term] id: UBERON:0006658 name: inter-phalangeal joint xref: FMA:42765 ! interphalangeal joint synonym: "interphalangeal joint" EXACT [FMA:42765] synonym: "inter-phalanx joint" EXACT [] is_a: UBERON:0002217 ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0003221 {cardinality="2"} ! phalanx relationship: connects UBERON:0003221 {notes="two phalanges in series"} ! phalanx relationship: part_of UBERON:0002544 {source="cjm"} ! digit xref: galen:InterphalangealJoint ! interphalangeal joint [Term] id: UBERON:0009767 ! proximal interphalangeal joint name: proximal interphalangeal joint synonym: "PIP joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "PIJ joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] intersection_of: UBERON:0006658 ! inter-phalangeal joint intersection_of: connects UBERON:0004302 ! proximal phalanx relationship: connects UBERON:0004301 ! middle phalanx xref: FMA:65022 ! proximal interphalangeal joint def: "An inter-phalangeal joint that connects a proximal phalanx." [OBOL:automatic] [Term] id: UBERON:0009768 ! distal interphalangeal joint name: distal interphalangeal joint synonym: "DIP joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "DIJ joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] intersection_of: UBERON:0006658 ! inter-phalangeal joint intersection_of: connects UBERON:0004300 ! distal phalanx relationship: connects UBERON:0004301 ! middle phalanx xref: FMA:65024 ! distal interphalangeal joint def: "An inter-phalangeal joint that connects a distal phalanx." [OBOL:automatic] [Term] id: UBERON:0007721 name: interphalangeal joint of pes def: "The interphalangeal articulations of the foot (articulations of the phalanges) are ginglymoid joints, and each has a plantar and two collateral ligaments. The arrangement of these ligaments is similar to that in the metatarsophalangeal articulations: the Extensor tendons supply the places of dorsal ligaments." [Wikipedia:Interphalangeal_articulations_of_the_foot] synonym: "interphalangeal joint of foot" EXACT [FMA:35225] synonym: "foot interphalangeal joint" EXACT [MESH:A02.835.583.378.900] synonym: "toe joint" RELATED [MESH:A02.835.583.378.900] xref: FMA:35225 ! interphalangeal joint of toe intersection_of: UBERON:0006658 ! inter-phalangeal joint intersection_of: part_of UBERON:0001466 ! pedal digit relationship: connects UBERON:0001449 {cardinality="2"} ! phalanx of pes relationship: connects UBERON:0001449 {notes="two in series"} ! phalanx of pes xref: ncithesaurus:Interphalangeal_Joint_of_the_Foot ! Interphalangeal Joint of the Foot xref: ncithesaurus:Toe_Joint ! toe joint xref: SCTID:182225005 ! Entire interphalangeal joint of toe xref: MESH:A02.835.583.378.900 ! toe joint synonym: "interphalangeal joint of toe" NARROW SENSU [NCBITaxon:9606, FMA:35225] xref: UMLS:C0040356 [Term] id: UBERON:0007722 name: interphalangeal joint of manus def: "The interphalangeal articulations of hand are hinge-joints of the phalanges of the hand. There are two sets (except in the thumb): \"proximal interphalangeal joints\" (PIP), those between the first (also called proximal) and second (intermediate) phalanges \"distal interphalangeal joints\" (DIP), those between the second and third (distal) phalanges A similar group of articulations also function in the toes." [Wikipedia:Interphalangeal_articulations_of_the_hand] comment: Editor notes: consider renaming: 'finger' is ambiguous as the term in some usages excludes the thumb (we include it) synonym: "IP joint" RELATED [FMA:35285] synonym: "interphalangeal joint of hand" EXACT [FMA:35285] synonym: "articulations of the digits" RELATED [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "interphalangeal articulations of hand" RELATED [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "interphalangeal joints of hand" RELATED [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "articulationes interphalangeae manus" EXACT [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "articulationes digitorum manus" EXACT [Wikipedia:Interphalangeal_articulations_of_the_hand] xref: FMA:35285 ! interphalangeal joint of finger intersection_of: UBERON:0006658 ! inter-phalangeal joint intersection_of: part_of UBERON:0002389 ! manual digit relationship: connects UBERON:0001436 {cardinality="2"} ! phalanx of manus relationship: connects UBERON:0001436 {notes="two in series"} ! phalanx of manus xref: ncithesaurus:Interphalangeal_Joint_of_the_Hand ! Interphalangeal Joint of the Hand xref: SCTID:303280009 ! Entire interphalangeal joint of hand synonym: "interphalangeal joint of finger" NARROW SENSU [NCBITaxon:9606, FMA:35285] xref: UMLS:C0016125 [Term] id: UBERON:0007723 name: interphalangeal joint of manual digit 1 synonym: "interphalangeal joint of first digit of hand" EXACT [FMA:35312] comment: Taxon notes: in humans, this connects proximal and distal phalanges of the thumb, so there is only a single inter-phalangeal joint - i.e. there is no distinct proximal and distal joints synonym: "interphalangeal joint of hand digit 1" EXACT [] synonym: "interphalangeal joint of manual digit 1" EXACT [] synonym: "interphalangeal joint of pollex" EXACT [] xref: FMA:35312 ! interphalangeal joint of thumb xref: EMAPA:25058 ! inter-phalangeal joint of digit 1 of fore-paw intersection_of: UBERON:0007722 ! interphalangeal joint of finger intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: connects UBERON:0003620 {cardinality="2"} ! manual digit 1 phalanx xref: SCTID:182192008 ! Entire interphalangeal joint of thumb synonym: "interphalangeal joint of thumb" NARROW SENSU [NCBITaxon:9606, FMA:35312] def: "An interphalangeal joint of manus that is part of a manual digit 1." [OBOL:automatic] [Term] id: UBERON:0007724 name: interphalangeal joint of pedal digit 1 synonym: "interphalangeal joint of first digit of pes" EXACT [FMA:35353] synonym: "interphalangeal joint of great toe" EXACT [FMA:35353] synonym: "interphalangeal joint of foot digit 1" EXACT [] synonym: "interphalangeal joint of pedal digit 1" EXACT [] synonym: "interphalangeal joint of hallux" EXACT [] xref: FMA:35353 ! interphalangeal joint of big toe xref: EMAPA:26430 ! inter-phalangeal joint of digit 1 of hind-paw intersection_of: UBERON:0007721 ! interphalangeal joint of toe intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: connects UBERON:0003640 {cardinality="2"} ! pedal digit 1 phalanx xref: SCTID:363671008 ! Entire interphalangeal joint of great toe synonym: "interphalangeal joint of first digit of foot" EXACT [FMA:35353] synonym: "interphalangeal joint of big toe" NARROW SENSU [NCBITaxon:9606, FMA:35353] def: "An interphalangeal joint of pes that is part of a pedal digit 1." [OBOL:automatic] [Term] id: UBERON:0007725 name: interphalangeal joint of pedal digit 2 synonym: "interphalangeal joint of second digit of foot" EXACT [FMA:35356] xref: FMA:35356 ! interphalangeal joint of second toe xref: EMAPA:26448 ! inter-phalangeal joint of digit 2 of hind-paw intersection_of: UBERON:0007721 ! interphalangeal joint of toe intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: connects UBERON:0003641 {cardinality="2"} ! pedal digit 2 phalanx synonym: "interphalangeal joint of second toe" NARROW SENSU [NCBITaxon:9606, FMA:35356] def: "An interphalangeal joint of pes that is part of a pedal digit 2." [OBOL:automatic] [Term] id: UBERON:0007726 name: interphalangeal joint of pedal digit 3 synonym: "interphalangeal joint of third digit of foot" EXACT [FMA:35359] xref: FMA:35359 ! interphalangeal joint of third toe xref: EMAPA:26454 ! inter-phalangeal joint of digit 3 of hind-paw intersection_of: UBERON:0007721 ! interphalangeal joint of toe intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: connects UBERON:0003642 {cardinality="2"} ! pedal digit 3 phalanx synonym: "interphalangeal joint of third toe" NARROW SENSU [NCBITaxon:9606, FMA:35359] def: "An interphalangeal joint of pes that is part of a pedal digit 3." [OBOL:automatic] [Term] id: UBERON:0007727 name: interphalangeal joint of pedal digit 4 synonym: "interphalangeal joint of fourth digit of foot" EXACT [FMA:35362] xref: FMA:35362 ! interphalangeal joint of fourth toe xref: EMAPA:26466 ! inter-phalangeal joint of digit 4 of hind-paw intersection_of: UBERON:0007721 ! interphalangeal joint of toe intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: connects UBERON:0003862 {cardinality="2"} ! pedal digit 4 phalanx synonym: "interphalangeal joint of fourth toe" NARROW SENSU [NCBITaxon:9606, FMA:35362] def: "An interphalangeal joint of pes that is part of a pedal digit 4." [OBOL:automatic] [Term] id: UBERON:0007728 name: interphalangeal joint of pedal digit 5 synonym: "interphalangeal joint of fifth digit of foot" EXACT [FMA:35365] synonym: "interphalangeal joint of fifth toe" EXACT [FMA:35365] xref: FMA:35365 ! interphalangeal joint of little toe xref: EMAPA:26478 ! inter-phalangeal joint of digit 5 of hind-paw intersection_of: UBERON:0007721 ! interphalangeal joint of toe intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: connects UBERON:0003863 {cardinality="2"} ! pedal digit 5 phalanx synonym: "interphalangeal joint of little toe" NARROW SENSU [NCBITaxon:9606, FMA:35365] def: "An interphalangeal joint of pes that is part of a pedal digit 5." [OBOL:automatic] [Term] id: UBERON:0007729 name: interphalangeal joint of manual digit 2 synonym: "interphalangeal joint of second digit of hand" EXACT [FMA:35397] synonym: "interphalangeal joint of second finger" EXACT [FMA:35397] xref: FMA:35397 ! interphalangeal joint of index finger xref: EMAPA:25061 ! inter-phalangeal joint of digit 2 of fore-paw intersection_of: UBERON:0007722 ! interphalangeal joint of finger intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: part_of UBERON:0003622 {source="EMAPA"} ! manual digit 2 relationship: connects UBERON:0003641 {cardinality="2"} ! pedal digit 2 phalanx synonym: "interphalangeal joint of index finger" NARROW SENSU [NCBITaxon:9606, FMA:35397] def: "An interphalangeal joint of manus that is part of a manual digit 2." [OBOL:automatic] [Term] id: UBERON:0007730 name: interphalangeal joint of manual digit 3 synonym: "interphalangeal joint of third digit of hand" EXACT [FMA:35400] synonym: "interphalangeal joint of third finger" EXACT [FMA:35400] xref: FMA:35400 ! interphalangeal joint of middle finger xref: EMAPA:25064 ! inter-phalangeal joint of digit 3 of fore-paw intersection_of: UBERON:0007722 ! interphalangeal joint of finger intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: connects UBERON:0003642 {cardinality="2"} ! pedal digit 3 phalanx synonym: "interphalangeal joint of middle finger" NARROW SENSU [NCBITaxon:9606, FMA:35400] def: "An interphalangeal joint of manus that is part of a manual digit 3." [OBOL:automatic] [Term] id: UBERON:0007731 name: interphalangeal joint of manual digit 4 synonym: "interphalangeal joint of fourth digit of hand" EXACT [FMA:35403] synonym: "interphalangeal joint of fourth finger" EXACT [FMA:35403] xref: FMA:35403 ! interphalangeal joint of ring finger xref: EMAPA:25067 ! inter-phalangeal joint of digit 4 of fore-paw intersection_of: UBERON:0007722 ! interphalangeal joint of finger intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: connects UBERON:0003862 {cardinality="2"} ! pedal digit 4 phalanx synonym: "interphalangeal joint of ring finger" NARROW SENSU [NCBITaxon:9606, FMA:35403] def: "An interphalangeal joint of manus that is part of a manual digit 4." [OBOL:automatic] [Term] id: UBERON:0007732 name: interphalangeal joint of manual digit 5 synonym: "interphalangeal joint of fifth digit of hand" EXACT [FMA:35407] synonym: "interphalangeal joint of fifth finger" EXACT [FMA:35407] xref: FMA:35407 ! Interphalangeal joint of little finger xref: EMAPA:25070 ! inter-phalangeal joint of digit 5 of fore-paw intersection_of: UBERON:0007722 ! interphalangeal joint of finger intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: connects UBERON:0003863 {cardinality="2"} ! pedal digit 5 phalanx synonym: "interphalangeal joint of little finger" NARROW SENSU [NCBITaxon:9606, FMA:35407] def: "An interphalangeal joint of manus that is part of a manual digit 5." [OBOL:automatic] [Term] id: UBERON:0000220 name: atlanto-occipital joint def: "The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital" [Wikipedia:Atlanto-occipital_joint] is_a: UBERON:0002217 {source="FMA"} ! synovial joint relationship: connects UBERON:0001676 ! occipital bone relationship: connects UBERON:0001092 ! cervical vertebra 1 relationship: part_of UBERON:0011138 ! post-cranial axial skeletal system synonym: "articulatio atlanto-occipitalis" EXACT [FMA:24939] synonym: "craniovertebral joint" EXACT [FMA:24939] synonym: "atlanto occipital joint" EXACT [] synonym: "occipito atlantal joint" EXACT [] synonym: "occipito-atlantal joint" EXACT [] synonym: "atlantooccipital joint" EXACT [] xref: FMA:24939 ! atlanto-occipital joint xref: ncithesaurus:Atlanto-occipital_Joint-Atlanto ! Occipital Joint xref: ncithesaurus:Atlanto-occipital_Joint ! atlanto-occipital joint xref: SCTID:361831006 ! Entire atlantooccipital joint synonym: "articulatio atlantooccipitalis" RELATED LATIN [Wikipedia:Atlanto-occipital_joint] xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png relationship: in_lateral_side_of UBERON:0006072 {source="FMA-abduced-lr"} ! cervical region of vertebral column xref: UMLS:C0004169 [Term] id: UBERON:0003694 name: atlanto-axial joint def: "The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas." [Wikipedia:Atlanto-axial_joint] synonym: "articulatio atlantoaxialis" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "articulatio atlantoepistrophica" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "atlantoaxial" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "lateral atlanto-axial joint" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "median atlanto-axial joint" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "atlanto axial joint" EXACT [GAID:250] synonym: "atlantoaxial joint" EXACT [GAID:250] xref: FMA:25524 ! Atlanto-axial joint xref: GAID:250 ! atlanto-axial joint xref: ncithesaurus:Atlanto-axial_Joint ! Atlanto-Axial Joint xref: OpenCyc:Mx4rwUUIHpwpEbGdrcN5Y29ycA ! atlanto axial joint xref: MESH:A02.835.583.097 ! atlanto-axial joint is_a: UBERON:0000982 ! skeletal joint relationship: connects UBERON:0001092 ! cervical vertebra 1 relationship: connects UBERON:0001093 ! cervical vertebra 2 relationship: part_of UBERON:0011138 ! post-cranial axial skeletal system xref: SCTID:361832004 ! Entire atlantoaxial joint xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png xref: UMLS:C0004168 [Term] id: UBERON:0011106 name: cruciate ligament of atlas def: "a cruciate ligament in the neck forming part of the atlanto-axial joint. It consists of the transverse ligament of the atlas, along with additional fibers above and below." [Wikipedia:Cruciate_ligament_of_the_dens] synonym: "cruciform ligament of atlas" EXACT [FMA:25018] synonym: "cruciform ligament of dens" EXACT [Wikipedia:Cruciate_ligament_of_the_dens] synonym: "cruciate ligament of dens" EXACT [Wikipedia:Cruciate_ligament_of_the_dens] synonym: "ligamentum cruciforme atlantis" EXACT LATIN [Wikipedia:Cruciate_ligament_of_the_dens] synonym: "triradiate ligament" RELATED [EMAPA:19010] is_a: UBERON:0000211 ! ligament relationship: part_of UBERON:0000220 {source="FMA", inconsistent_with="Wikipedia"} ! atlanto-occipital joint xref: FMA:25018 ! cruciate ligament of atlas xref: EMAPA:19010 ! cruciate ligament xref: SCTID:182362005 ! Entire cruciate ligament of axis [Term] id: UBERON:0006659 ! cruciate ligament of knee name: cruciate ligament of knee def: "One of a pair of ligaments arranged like a letter X.[1] They occur in several joints of the body, such as the knee. In a fashion similar to the cords in a toy Jacob's ladder, the crossed ligaments stabilize the joint while allowing a very large range of motion[WP]." [Wikipedia:Cruciate_ligament] synonym: "cruciform ligament" BROAD [Wikipedia:Cruciate_ligament] synonym: "cruciate ligament" BROAD [FMA:44611] xref: FMA:44611 ! cruciate ligament is_a: UBERON:0000211 ! ligament relationship: part_of UBERON:0001485 {source="FMA"} ! knee joint disjoint_from: UBERON:0011106 ! cruciate ligament of atlas xref: galen:CruciateLigament [Term] id: UBERON:0003671 name: anterior cruciate ligament of knee joint synonym: "anterior cruciate ligament" EXACT [FMA:44614] xref: FMA:44614 ! Anterior cruciate ligament xref: GAID:122 ! anterior cruciate ligament xref: ncithesaurus:Anterior_Cruciate_Ligament ! Anterior Cruciate Ligament xref: galen:AnteriorCruciateLigament ! anterior cruciate ligament xref: OpenCyc:Mx4r77KC8RuaEd2f4ADggVfexA ! anterior cruciate ligament xref: MESH:A02.513.514.100 ! anterior cruciate ligament xref: SCTID:182443006 ! Entire anterior cruciate ligament of knee joint is_a: UBERON:0006659 ! cruciate ligament xref: UMLS:C0078960 [Term] id: UBERON:0003680 name: posterior cruciate ligament of knee joint synonym: "posterior cruciate ligament" EXACT [FMA:44617] xref: FMA:44617 ! Posterior cruciate ligament xref: GAID:129 ! posterior cruciate ligament xref: ncithesaurus:Posterior_Cruciate_Ligament ! Posterior Cruciate Ligament xref: galen:PosteriorCruciateLigament ! posterior cruciate ligament xref: MESH:A02.513.514.600 ! posterior cruciate ligament xref: SCTID:182445004 ! Entire posterior cruciate ligament of knee joint is_a: UBERON:0006659 ! cruciate ligament xref: UMLS:C0080039 [Term] id: UBERON:0006661 name: epicranial aponeurosis def: "The galea aponeurotica (epicranial aponeurosis, aponeurosis epicranialis) is a tough layer of dense fibrous tissue which covers the upper part of the cranium; behind, it is attached, in the interval between its union with the Occipitales, to the external occipital protuberance and highest nuchal lines of the occipital bone; in front, it forms a short and narrow prolongation between its union with the Frontales. On either side it gives origin to the Auriculares anterior and superior; in this situation it loses its aponeurotic character, and is continued over the temporal fascia to the zygomatic arch as a layer of laminated areolar tissue. It is closely connected to the integument by the firm, dense, fibro-fatty layer which forms the superficial fascia of the scalp: it is attached to the pericranium by loose cellular tissue, which allows the aponeurosis, carrying with it the integument to move through a considerable distance." [Wikipedia:Galea_aponeurotica] synonym: "cranial aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] synonym: "epicranial aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] synonym: "galea aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] synonym: "galeal aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] synonym: "Epicranial aponeurosis" EXACT [FMA:46768] synonym: "Epicranius aponeurosis" EXACT [FMA:46768] synonym: "Galea aponeurotica" EXACT [FMA:46768] xref: FMA:46768 ! Aponeurosis of epicranius xref: EMAPA:19210 ! epicranial aponeurosis is_a: UBERON:0006614 ! aponeurosis relationship: part_of UBERON:0000403 {source="FMA"} ! scalp synonym: "aponeurosis epicranialis" EXACT LATIN [FMA:TA, FMA:46768] xref: SCTID:368677009 ! Entire galea aponeurotica synonym: "galea aponeurotica; aponeurosis epicranialis" RELATED LATIN [Wikipedia:Galea_aponeurotica] xref: http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray378.png synonym: "aponeurosis of epicranius" EXACT [FMA:46768] [Term] id: UBERON:0006662 name: musculo-phrenic vein xref: FMA:4732 ! Musculophrenic vein xref: EMAPA:19222 ! musculo-phrenic vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0001589 ! internal thoracic vein relationship: tributary_of UBERON:0001589 {source="FMA/obol"} ! internal thoracic vein xref: SCTID:1895000 ! Entire musculophrenic vein synonym: "musculophrenic vein" EXACT [FMA:4732] [Term] id: UBERON:0006663 name: hemiazygos vein def: "The hemiazygos vein (vena azygos minor inferior) is a vein running superiorly in the lower thoracic region, just to the left side of the vertebral column." [Wikipedia:Hemiazygos_vein] comment: Taxon notes: The major anatomic variation between the pig and other mammalian species is the presence of the large left azygos vein, which enters the coronary sinus (Fig. 1). In other mammals, hemiazygos vein enters the pre- cava. synonym: "hemiazygos" RELATED [Wikipedia:Hemiazygos_vein] synonym: "hemiazygos veins" RELATED [Wikipedia:Hemiazygos_vein] synonym: "hemiazygous vein" RELATED [Wikipedia:Hemiazygos_vein] synonym: "hemi-azygos vein" EXACT [FMA:4944] synonym: "hemiazygous vein" EXACT [FMA:4944] synonym: "inferior hemi-azygos vein" EXACT [FMA:4944] xref: FMA:4944 ! Hemiazygos vein xref: EMAPA:18251 ! hemiazygos vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0001594 ! azygos vein relationship: develops_from UBERON:0008267 {source="ISBN-10:0443065837"} ! left supracardinal vein relationship: tributary_of UBERON:0001594 {source="FMA/obol"} ! azygos vein synonym: "vena hemiazygos" EXACT LATIN [FMA:TA, FMA:4944] xref: SCTID:244408009 ! Entire hemiazygous vein xref: EHDAA2:0004534 ! hemiazygous vein synonym: "vena hemiazygos" RELATED LATIN [Wikipedia:Hemiazygos_vein] xref: http://upload.wikimedia.org/wikipedia/commons/3/3e/Gray480.png [Term] id: UBERON:0006664 name: greater palatine artery def: "The greater palatine artery is a terminal branch of the maxillary artery. It branches off of the maxillary artery in the pterygopalatine fossa and descends through the greater palatine foramen along with the greater palatine nerve and supplies the hard palate. It also anastomosis through the incisive canal with the sphenopalatine artery to supply the nasal cavity." [Wikipedia:Greater_palatine_artery] comment: todo - check for synonymy between greater and major; branch_of relation is made in FMA at level of descending GPA xref: MA:0001993 ! major palatine artery xref: FMA:49795 ! Greater palatine artery xref: EMAPA:18754 ! greater palatine artery is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0001616 ! maxillary artery xref: SCTID:312163002 ! Greater palatine artery synonym: "arteria palatina major" RELATED LATIN [Wikipedia:Greater_palatine_artery] synonym: "major palatine artery" EXACT [MA:0001993] [Term] id: UBERON:0006665 name: accessory hemiazygos vein def: "The accessory hemiazygos vein (vena azygos minor superior) is a vein on the left side of the vertebral column that generally drains the fifth through eighth intercostal spaces on the left side of the body[WP]." [Wikipedia:Accessory_hemiazygos_vein] comment: todo - add superclass synonym: "Accessory hemi-azygos vein" EXACT [FMA:5011] synonym: "Superior hemi-azygos vein" EXACT [FMA:5011] synonym: "Vena azygos accessoria" EXACT [FMA:5011] xref: FMA:5011 ! Accessory hemiazygos vein xref: EMAPA:19217 ! accessory hemiazygos vein is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001594 {source="FMA/obol"} ! azygos vein synonym: "vena hemiazygos accessoria" EXACT LATIN [FMA:TA, FMA:5011] synonym: "vena hemiazygos accessoria" RELATED LATIN [Wikipedia:Accessory_hemiazygos_vein] xref: http://upload.wikimedia.org/wikipedia/commons/3/3e/Gray480.png [Term] id: UBERON:0006668 name: carotid canal def: "On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]." [Wikipedia:Carotid_canal] xref: FMA:55805 ! Carotid canal xref: EMAPA:18707 ! carotid canal is_a: UBERON:0005744 ! cranial conduit synonym: "canalis caroticus" RELATED LATIN [Wikipedia:Carotid_canal] xref: http://upload.wikimedia.org/wikipedia/commons/4/4c/Gray141.png [Term] id: UBERON:0006669 name: alveolar canal def: "The infratemporal surface of the maxilla is pierced about its center by the apertures of the alveolar canals, which transmit the posterior superior alveolar vessels and nerves[WP]." [Wikipedia:Alveolar_canals] xref: FMA:57743 ! Alveolar canal xref: EMAPA:25099 ! alveolar canal is_a: UBERON:0005744 ! cranial conduit relationship: part_of UBERON:0001710 {source="EMAPA"} ! lower jaw region synonym: "canales alveolares maxillae" RELATED LATIN [Wikipedia:Alveolar_canals] xref: http://upload.wikimedia.org/wikipedia/commons/7/71/Gray157.png [Term] id: UBERON:0006670 name: central tendon synonym: "central tendon of diaphragm" EXACT [FMA:58279] synonym: "centrum tendineum" EXACT [FMA:58279] xref: FMA:58279 ! Central tendon xref: EMAPA:17702 ! central tendon xref: VHOG:0001399 ! central tendon is_a: UBERON:0000043 ! tendon relationship: attaches_to UBERON:0002359 ! fibrous pericardium synonym: "centrum tendineum diaphragmatis" EXACT LATIN [FMA:TA, FMA:58279] xref: ncithesaurus:Central_Tendon_of_the_Diaphragm ! Central Tendon of the Diaphragm xref: SCTID:244943002 ! Entire central tendon of diaphragm relationship: immediate_transformation_of UBERON:0006239 {evidence="definitional"} ! future central tendon property_value: homology_notes "In mammals, the diaphragm muscle divides the thoracoabdominal cavity into thorax and abdomen. In most mammals, the diaphragm is a flat sheet with muscle fibers radiating outward from a central tendon, and the diaphragm's apposition to the cranial surface of the liver gives it a dome-shape. Muscle fiber contraction reduces the curvature of the dome, thereby expanding the thoracic cavity and aspirating air into the lungs.[well established][VHOG]" xsd:string {external_class="VHOG:0001399", ontology="VHOG", source="DOI:10.1016/j.resp.2006.06.003", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0230162 [Term] id: UBERON:0006671 name: orbital fat pad synonym: "intraorbital fat pad" EXACT [FMA:59005] synonym: "orbital fat" EXACT [FMA:59005] synonym: "retrobulbar fat" EXACT [FMA:59005] synonym: "orbital fat body" EXACT [FMA:59005] xref: FMA:59005 ! orbital fat body xref: EMAPA:19152 ! orbital fat pad intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0001697 ! orbital region relationship: part_of UBERON:0004088 {source="FMA"} ! ocular region xref: SCTID:363656009 ! Orbital fat structure synonym: "orbital fat body" EXACT [FMA:59005] def: "A fat pad that is part of a orbital region." [OBOL:automatic] [Term] id: UBERON:0006672 name: incisive canal xref: FMA:59107 ! Incisive canal xref: EMAPA:19034 ! incisive canal is_a: UBERON:0005744 ! cranial conduit relationship: part_of UBERON:0003216 ! hard palate [Term] id: UBERON:0006673 name: mandibular canal def: "In humans, the mandibular canal is a canal within the mandible that contains the inferior alveolar nerve, inferior alveolar artery, and inferior alveolar vein. It runs obliquely downward and forward in the ramus, and then horizontally forward in the body, where it is placed under the alveoli and communicates with them by small openings" [Wikipedia:Mandibular_canal] comment: AO notes: TAO has mandibular sensory canal, which is part of the lateral line system xref: FMA:59473 ! Mandibular canal xref: EMAPA:19161 ! mandibular canal is_a: UBERON:0005744 ! cranial conduit xref: SCTID:368876003 ! Entire mandibular canal xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray1003.png [Term] id: UBERON:0006674 name: inguinal ring xref: FMA:65075 ! Inguinal ring xref: EMAPA:19172 ! inguinal ring of female reproductive system xref: EMAPA:29307 ! inguinal ring of male reproductive system is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0006204 ! inguinal ligament xref: SCTID:278830004 ! Entire inguinal ring [Term] id: UBERON:0006677 name: surface of epithelium synonym: "epithelium surface" EXACT [FMA:70997] xref: FMA:70997 ! Surface of epithelium intersection_of: UBERON:0000015 ! anatomical boundary intersection_of: adjacent_to UBERON:0000483 ! epithelium def: "An anatomical boundary that adjacent_to a epithelium." [OBOL:automatic] [Term] id: UBERON:0006679 ! carina of trachea name: carina of trachea def: "In anatomy, the carina is a cartilaginous ridge within the trachea that runs anteroposteriorly between the two primary bronchi at the site of the tracheal bifurcation at the lower end of the trachea (usually at the level of the 4th to 5th thoracic vertebrae). The mucous membrane of the carina is the most sensitive area of the trachea and larynx for triggering a cough reflex. Widening and distortion of the carina is a serious sign because it usually indicates carcinoma of the lymph nodes around the region where the trachea divides. Tracheobronchial injury, an injury to the airways, occurs within 2.5 cm of the carina 40b80% of the time." [Wikipedia:Carina_of_trachea] synonym: "bifurcation of the trachea" RELATED [Wikipedia:Carina_of_trachea] synonym: "carina %28anatomy%29" RELATED [Wikipedia:Carina_of_trachea] synonym: "carina of trachea" RELATED [Wikipedia:Carina_of_trachea] synonym: "carina" BROAD [FMA:7465] synonym: "tracheal carina" EXACT [FMA:7465] synonym: "carina tracheae" EXACT [EMAPA:18407] xref: FMA:7465 ! Carina of trachea xref: EMAPA:18407 ! carina tracheae is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0003126 ! trachea relationship: connects UBERON:0003126 ! trachea relationship: connects UBERON:0002182 ! main bronchus xref: ncithesaurus:Carina ! Carina xref: SCTID:181214003 ! Entire carina synonym: "carina tracheae" RELATED LATIN [Wikipedia:Carina_of_trachea] xref: http://upload.wikimedia.org/wikipedia/commons/f/f2/Diagrama_de_los_pulmones-c.svg xref: UMLS:C0225594 [Term] id: UBERON:0006680 name: trachealis def: "A smooth muscle tissue that bridges the gap between free ends of C-shaped cartilages at the posterior border of the trachea, adjacent to the esophagus. A primary function of the trachealis is to constrict the windpipe, allowing for higher velocity of air in the windpipe during coughing[WP, modified]." [Wikipedia:Trachealis_muscle] synonym: "tracheal muscle" EXACT [FMA:7466] synonym: "trachealis muscle" EXACT [FMA:7466] xref: FMA:7466 ! Trachealis xref: EMAPA:19193 ! trachealis is_a: UBERON:0001135 ! smooth muscle tissue relationship: part_of UBERON:0003387 ! smooth muscle of trachea xref: SCTID:197333002 ! Entire tracheal muscle [Term] id: UBERON:0006681 name: interthalamic adhesion synonym: "Interthalamic connection" EXACT [FMA:74869] synonym: "Middle commissure" EXACT [FMA:74869] xref: FMA:74869 ! Interthalamic adhesion xref: EMAPA:18546 ! interthalamic adhesion is_a: UBERON:0001020 ! commissure [Term] id: UBERON:0006682 name: hypoglossal canal xref: FMA:75370 ! Hypoglossal canal xref: EMAPA:19012 ! hypoglossal canal is_a: UBERON:0004111 ! anatomical conduit xref: SCTID:139380001 ! Entire hypoglossal canal [Term] id: UBERON:0006683 name: posterior fontanelle def: "In humans, the posterior fontanelle (or occipital fontanelle) is a gap between bones in the skull, triangular in form and situated at the junction of the sagittal suture and lambdoidal suture. It generally closes in 6–8 weeks from birth. A delay in closure is associated with congential hypothyroidism." [Wikipedia:Posterior_fontanelle] synonym: "fonticulus posterior" EXACT LATIN [] synonym: "occipital posterior" EXACT LATIN [] synonym: "posterior fontanelle of skull" EXACT LATIN [] xref: FMA:75440 ! Posterior fontanelle xref: EMAPA:19200 ! posterior fontanelle xref: SCTID:244681005 ! Entire posterior fontanel of skull is_a: UBERON:0002221 ! fontanelle relationship: connects UBERON:0002491 ! lambdoid suture relationship: connects UBERON:0002492 ! sagittal suture xref: http://upload.wikimedia.org/wikipedia/commons/b/b3/Gray197.png [Term] id: UBERON:0006684 name: sphenoidal fontanelle def: "." [Wikipedia:Pterion] comment: See also FMA:264720 ! pterion synonym: "sphenoidal fontanelle" RELATED [Wikipedia:Pterion] xref: FMA:75441 ! Sphenoidal fontanelle xref: EMAPA:19229 ! sphenoidal fontanelle xref: SCTID:136955008 ! Entire sphenoidal fontanel of skull is_a: UBERON:0002221 ! fontanelle xref: http://upload.wikimedia.org/wikipedia/commons/6/6a/Pterion.PNG [Term] id: UBERON:0006685 name: pharyngeal tubercle xref: FMA:75746 ! Pharyngeal tubercle xref: EMAPA:19250 ! pharyngeal tubercle is_a: UBERON:0005813 {source="FMA"} ! tubercle relationship: part_of UBERON:0001042 {source="EMAPA"} ! chordate pharynx [Term] id: UBERON:0006686 name: spinal vein synonym: "Spinal vein" EXACT [FMA:76735] xref: FMA:76735 ! Spinal branch xref: EMAPA:18255 ! spinal vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001130 ! vertebral column synonym: "vena spinalis" EXACT LATIN [FMA:TA, FMA:76735] xref: SCTID:181376008 ! Spinal vein synonym: "spinal branch" RELATED [FMA:76735] def: "A vein that is part of a vertebral column." [OBOL:automatic] [Term] id: UBERON:0006687 name: median sacral vein xref: FMA:77168 ! Median sacral vein xref: EMAPA:26064 ! median sacral vein is_a: UBERON:0001638 ! vein relationship: tributary_of UBERON:0001317 {source="FMA/obol"} ! internal iliac vein [Term] id: UBERON:0006688 name: sublingual caruncle def: "The sublingual caruncle is a site on either side of the frenulum linguae on the sublingual surface of the tongue. There it denotes the site at which the submandibular gland empties into the oral cavity." [Wikipedia:Sublingual_caruncle] xref: FMA:77273 ! Sublingual caruncle xref: EMAPA:18961 ! sublingual caruncle is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001723 ! tongue xref: SCTID:85139009 ! Sublingual caruncle synonym: "caruncula sublingualis" RELATED LATIN [Wikipedia:Sublingual_caruncle] xref: http://upload.wikimedia.org/wikipedia/commons/1/13/Gray1202.png [Term] id: UBERON:0006689 name: frenulum of tongue def: "The frenulum of tongue (or lingual frenulum) is the frenulum of the tongue, a small fold of mucous membrane extending from the floor of the mouth to the midline of the underside of the tongue." [Wikipedia:Frenulum_of_tongue] synonym: "frenulum lingu%c3%a6" RELATED [Wikipedia:Frenulum_of_tongue] synonym: "frenulum linguae" RELATED [Wikipedia:Frenulum_of_tongue] synonym: "frenulum of the tongue" RELATED [Wikipedia:Frenulum_of_tongue] synonym: "lingual frenulum" RELATED [Wikipedia:Frenulum_of_tongue] synonym: "lingual frenum" RELATED [Wikipedia:Frenulum_of_tongue] synonym: "tongue frenulum" EXACT [FMA:54659] synonym: "frenulum" BROAD [] synonym: "oral frenulum" EXACT [HP:0000190] synonym: "oral frenula" EXACT PLURAL [HP:0000190] synonym: "frenulum linguae" EXACT LATIN [Wikipedia:Frenulum_of_tongue] xref: ncithesaurus:Frenulum ! Frenulum xref: FMA:54659 ! frenulum of tongue xref: EMAPA:18656 ! frenulum of tongue of pharynx of foregut xref: EMAPA:18874 ! frenulum of tongue of pharynx of gut is_a: UBERON:0000344 ! mucosa relationship: part_of UBERON:0001723 ! tongue xref: http://upload.wikimedia.org/wikipedia/commons/1/13/Gray1202.png xref: SCTID:264113009 ! Entire frenulum linguae xref: UMLS:C2339893 [Term] id: UBERON:0006690 name: deep dorsal vein of clitoris xref: FMA:77504 ! Deep dorsal vein of clitoris xref: EMAPA:19218 ! deep dorsal vein of clitoris is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0002411 ! clitoris relationship: tributary_of UBERON:0001317 {source="FMA/obol"} ! internal iliac vein xref: SCTID:25834009 ! Entire deep dorsal vein of clitoris [Term] id: UBERON:0006691 name: tentorium cerebelli def: "The tentorium cerebelli or cerebellar tentorium is an extension of the dura mater that separates the cerebellum from the inferior portion of the occipital lobes." [Wikipedia:Tentorium_cerebelli] synonym: "infratentorial neoplasms" RELATED [Wikipedia:Tentorium_cerebelli] synonym: "supratentorial neoplasms" RELATED [Wikipedia:Tentorium_cerebelli] synonym: "Cerebellar tentorium" EXACT [FMA:83966] xref: VHOG:0001298 ! tentorium cerebelli xref: FMA:83966 ! Tentorium cerebelli xref: EMAPA:18210 ! tentorium cerebelli is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002363 ! dura mater xref: ncithesaurus:Tentorium_Cerebelli ! Tentorium Cerebelli xref: SCTID:244428008 ! Entire tentorium cerebelli xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Illu_tentorium.jpg property_value: external_definition "The tentorium cerebelli or cerebellar tentorium (Latin: [][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001298", date_retrieved="2012-09-17", source="http://bgee.unil.ch/"} xref: UMLS:C0228121 [Term] id: UBERON:0006692 name: vertebral canal def: "The spinal canal (or vertebral canal or spinal cavity) is the space in vertebrae through which the spinal cord passes. It is a process of the dorsal human body cavity. This canal is enclosed within the vertebral foramen of the vertebrae. In the intervertebral spaces, the canal is protected by the ligamentum flavum posteriorly and the posterior longitudinal ligament anteriorly. The outermost layer of the meninges, the dura mater, is closely associated with the arachnoid which in turn is loosely connected to the innermost layer of the meninges, the pia mater. The meninges divide the spinal canal into the epidural space and the subarachnoid space. The pia mater is closely attached to the spinal cord. A subdural space is generally only present due to trauma and/or pathological situations. The subarachnoid space is filled with cerebrospinal fluid and contains the vessels that supply the spinal cord, namely the anterior spinal artery and the paired posterior spinal arteries, accompanied by a corresponding spinal veins. The spinal arteries form anastomoses known as the vasocorona of the spinal cord. The epidural space contains loose fatty tissue, and a network of large, thin-walled blood vessels called the anterior vertebral venous plexus and the posterior vertebral venous plexus The spinal canal was first described by Jean Fernel." [Wikipedia:Spinal_canal] comment: todo - check neural vs vertebral canal; embryonic vs adult? synonym: "spinal cavity" RELATED [Wikipedia:Spinal_canal] synonym: "vertebral canal" RELATED [Wikipedia:Spinal_canal] synonym: "foramen vertebrale" RELATED [AAO:0000693] synonym: "spinal canal" RELATED [AAO:0000693] synonym: "neural canal" RELATED [AAO:0000693] xref: GAID:242 ! spinal canal xref: AAO:0000693 ! neural canal xref: FMA:9680 ! Vertebral canal xref: EMAPA:25440 ! vertebral canal of T1 of vertebra of thoracic region xref: EMAPA:25448 ! vertebral canal of T10 of vertebra of thoracic region xref: EMAPA:25456 ! vertebral canal of T11 of vertebra of thoracic region xref: EMAPA:25464 ! vertebral canal of T12 of vertebra of thoracic region xref: EMAPA:25472 ! vertebral canal of T13 of vertebra of thoracic region xref: EMAPA:25480 ! vertebral canal of T2 of vertebra of thoracic region xref: EMAPA:25488 ! vertebral canal of T3 of vertebra of thoracic region xref: EMAPA:25496 ! vertebral canal of T4 of vertebra of thoracic region xref: EMAPA:25504 ! vertebral canal of T5 of vertebra of thoracic region xref: EMAPA:25512 ! vertebral canal of T6 of vertebra of thoracic region xref: EMAPA:25520 ! vertebral canal of T7 of vertebra of thoracic region xref: EMAPA:25528 ! vertebral canal of T8 of vertebra of thoracic region xref: EMAPA:25536 ! vertebral canal of T9 of vertebra of thoracic region xref: EMAPA:25544 ! vertebral canal of Tl1 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25552 ! vertebral canal of Tl10 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25560 ! vertebral canal of Tl11 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25568 ! vertebral canal of Tl12 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25576 ! vertebral canal of Tl13 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25584 ! vertebral canal of Tl14 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25592 ! vertebral canal of Tl15 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25600 ! vertebral canal of Tl16 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25608 ! vertebral canal of Tl17 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25616 ! vertebral canal of Tl18 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25624 ! vertebral canal of Tl19 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25632 ! vertebral canal of Tl2 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25640 ! vertebral canal of Tl3 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25648 ! vertebral canal of Tl4 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25656 ! vertebral canal of Tl5 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25664 ! vertebral canal of Tl6 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25672 ! vertebral canal of Tl7 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25680 ! vertebral canal of Tl8 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25688 ! vertebral canal of Tl9 of vertebra of axial skeleton of skeleton of tail of embryo xref: EMAPA:25731 ! vertebral canal of C3 of vertebra of cervical region xref: EMAPA:25738 ! vertebral canal of C4 of vertebra of cervical region xref: EMAPA:25745 ! vertebral canal of C5 of vertebra of cervical region xref: EMAPA:25752 ! vertebral canal of C6 of vertebra of cervical region xref: EMAPA:25759 ! vertebral canal of C7 of vertebra of cervical region xref: EMAPA:26521 ! vertebral canal of C1 of vertebra of cervical region xref: EMAPA:26537 ! vertebral canal of C2 of vertebra of cervical region is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0001130 ! vertebral column relationship: surrounds UBERON:0002240 ! spinal cord xref: ncithesaurus:Vertebral_Canal ! Vertebral Canal xref: ncithesaurus:Neural_Canal ! neural canal synonym: "c. vertebralis" RELATED LATIN [Wikipedia:Spinal_canal] xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Gray82.png property_value: external_definition "Canal formed by the vertebral centra ventrally, the pedicels laterally, and the neural arches dorsally that encloses and protects the spinal cord.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000693", date_retrieved="2012-06-20", source="AAO:LAP"} xref: SCTID:361746009 ! Entire spinal canal xref: UMLS:C1522467 xref: UMLS:C0037922 [Term] id: UBERON:0006693 name: protein-based cuticle def: "An example of this is found in Caenorhabditis elegans" [GO:0007592] is_a: UBERON:0001002 ! cuticle [Term] id: UBERON:0006694 name: cerebellum vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002037 ! cerebellum [Term] id: UBERON:0002206 name: mammillary body def: "The mammilary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei[GO]." [Wikipedia:Mammillary_body] subset: uberon_slim subset: vertebrate_core synonym: "corpus mamillare" EXACT [ZFA:0000334] xref: FMA:74877 ! Mammillary body xref: GAID:652 ! mamillary body xref: MA:0000174 ! mammillary body xref: NIF_GrossAnatomy:birnlex_865 ! Mammillary body xref: ZFA:0000334 ! corpus mamillare xref: ncithesaurus:Mamillary_Body ! Mamillary Body xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Gray1180.png/200px-Gray1180.png xref: MESH:A08.186.211.730.385.357.362.500 ! mamillary body xref: ABA:MBO ! Mammillary body is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002272 {source="ABA"} ! medial zone of hypothalamus relationship: part_of UBERON:0002770 {source="GO definition"} ! posterior hypothalamic region relationship: part_of UBERON:0000349 {source="GO"} ! limbic system relationship: spatially_disjoint_from UBERON:0002634 {source="ABA"} ! anterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002035 {source="ABA"} ! medial preoptic nucleus relationship: spatially_disjoint_from UBERON:0002706 {source="ABA"} ! posterior nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0001935 {source="ABA"} ! ventromedial nucleus of hypothalamus xref: SCTID:279306001 ! Entire mammillary body xref: TAO:0000334 ! corpus mamillare synonym: "corpus mamillare" RELATED LATIN [Wikipedia:Mammillary_body] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Gray1180.png xref: UMLS:C0024670 [Term] id: UBERON:0006695 ! mammillary axonal complex name: mammillary axonal complex def: "The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain[GO]." [GO:0061373] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0002206 ! mammillary body [Term] id: UBERON:0006696 alt_id: UBERON:0009642 name: mammillothalamic axonal tract def: "The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit[GO]." [GO:0061374, Wikipedia:Mammillothalamic_fasciculus] comment: The mammillothalamic fasciculus arises from cells in both the medial and lateral nuclei of the mammillary body and by fibers that are directly continued from the fornix. The Mammillothalamic fasciculus then connects the mammillary body to the dorsal tegmental nuclei, the ventral tegmental nuclei, and the anterior thalamic nucleus [WP] synonym: "mammillothalamic tract" EXACT [FMA:83849] synonym: "fasciculus mammillothalamicus" EXACT LATIN [FMA:TA] synonym: "mammillothalamic fasciculus" EXACT [FMA:83849] synonym: "vicq d'azyr's bundle" EXACT [FMA:83849] synonym: "bundle of vicq d%27azyr" RELATED [Wikipedia:Mammillothalamic_fasciculus] synonym: "bundle of vicq d%e2%80%99azyr" RELATED [Wikipedia:Mammillothalamic_fasciculus] synonym: "mamillo-thalamic tract" RELATED [Wikipedia:Mammillothalamic_fasciculus] synonym: "mammillo-thalamic fasciculus" RELATED [Wikipedia:Mammillothalamic_fasciculus] synonym: "mammillothalamic tract" RELATED [Wikipedia:Mammillothalamic_fasciculus] synonym: "thalamomammillary fasciculus" RELATED [Wikipedia:Mammillothalamic_fasciculus] xref: NIF_GrossAnatomy:nlx_anat_1010016 ! Mammillothalamic tract xref: FMA:83849 ! mammillothalamic tract synonym: "fasciculus mammillothalamicus" RELATED LATIN [Wikipedia:Mammillothalamic_fasciculus] is_a: UBERON:0001018 ! axon tract relationship: part_of UBERON:0001894 ! diencephalon relationship: part_of UBERON:0006695 ! mammillary axonal complex relationship: continuous_with UBERON:0001898 ! hypothalamus relationship: continuous_with UBERON:0001897 ! thalamus [Term] id: UBERON:0002990 name: mammillothalamic tract of hypothalamus xref: FMA:62059 ! Mammillothalamic tract of hypothalamus xref: NIF_GrossAnatomy:birnlex_855 ! Mammillothalamic tract of hypothalamus is_a: UBERON:0002316 ! white matter of neuraxis relationship: part_of UBERON:0002770 {source="FMA"} ! posterior hypothalamic region relationship: part_of UBERON:0006695 ! mammillary axonal complex xref: SCTID:369139008 ! Entire mammillothalamic tract of hypothalamus [Term] id: UBERON:0006697 name: mammillotectal axonal tract def: "The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus." [GO:0061375] is_a: UBERON:0001018 ! axon tract relationship: part_of UBERON:0006695 ! mammillary axonal complex relationship: continuous_with UBERON:0001894 ! diencephalon relationship: continuous_with UBERON:0001945 ! superior colliculus [Term] id: UBERON:0006698 alt_id: UBERON:0002725 name: mammillotegmental axonal tract def: "The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons" [GO:0061376] synonym: "Gudden tract" EXACT [FMA:62058] synonym: "mammillotegmental tract" EXACT [FMA:62058] synonym: "von Gudden's tract" EXACT [FMA:62058] synonym: "mammillotegmental tract of hypothalamus" EXACT [NIF_GrossAnatomy:birnlex_1497] synonym: "mammillotegmental fasciculus" EXACT [FMA:62058] xref: FMA:62058 ! mammillotegmental fasciculus xref: NIF_GrossAnatomy:birnlex_1497 ! Mammillotegmental fasciculus xref: SCTID:369140005 ! Entire mammillotegmental tract of hypothalamus is_a: UBERON:0001018 ! axon tract relationship: part_of UBERON:0006695 ! mammillary axonal complex relationship: part_of UBERON:0002770 {source="FMA"} ! posterior hypothalamic region relationship: continuous_with UBERON:0000988 ! pons relationship: continuous_with UBERON:0001943 ! midbrain tegmentum [Term] id: UBERON:0009635 name: parachordal cartilage def: "Chondrocranium chondrification center that fuses with cartilages derived from sclerotome region of occipital somites forming occipital bone, hypoglossal canals and foramen magnum." [ISBN10:1588903958, UBERON:cjm] synonym: "parachordal cartilages" EXACT PLURAL [ZFA:0001423] xref: TAO:0001423 ! parachordal cartilage is_a: UBERON:0003932 {source="ZFA"} ! cartilaginous elemenet of chondrocranium relationship: overlaps UBERON:0003110 {source="ZFA"} ! otic region relationship: overlaps UBERON:0005902 {source="ZFA"} ! occipital region xref: ZFA:0001423 ! parachordal cartilage xref: ncithesaurus:Parachordal_Cartilage ! Parachordal Cartilage property_value: external_definition "Rod-shaped paired cartilages on either side of the notochord. They unite, forming the base of the chondrocranium and are replaced by the prootic bones.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001423", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C1518887 [Term] id: UBERON:0009636 name: prechordal cartilage def: "Chondrocranium chondrification center that that forms anterior body of sphenoid, containing the sella turcica and posterior body of sphenoid." [ISBN10:1588903958, UBERON:cjm] comment: classified as part of chondrocranium based on developmental relationships is_a: UBERON:0003932 ! cartilaginous elemenet of chondrocranium [Term] id: UBERON:0009640 ! hypophyseal cartilage name: hypophyseal cartilage is_a: UBERON:0003932 ! cartilaginous elemenet of chondrocranium comment: classified as part of chondrocranium based on developmental relationships def: "forms around the developing pituitary, and together with prechordal cartilages creates body of sphenoid bone" [ISBN10:1588903958] [Term] id: UBERON:0009639 name: body of sphenoid def: "The body of the sphenoid bone, more or less cubical in shape, is hollowed out in its interior to form two large cavities, the sphenoidal air sinuses, which are separated from each other by a septum." [Wikipedia:Body_of_sphenoid_bone] synonym: "Entire body of sphenoid bone" EXACT [] synonym: "body of sphenoidal bone" EXACT [FMA:52867] synonym: "central body of sphenoid" EXACT [FMA:52867] synonym: "corpus (os sphenoidale)" EXACT [FMA:52867] synonym: "sphenoid body" EXACT [FMA:52867] is_a: UBERON:0001474 ! bone element relationship: part_of UBERON:0001677 {source="FMA"} ! sphenoid bone relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium relationship: part_of UBERON:0002241 {source="cjm"} ! chondrocranium relationship: develops_from UBERON:0009640 {source="ISBN10:1588903958"} ! hypophyseal cartilage relationship: develops_from UBERON:0009636 {source="ISBN10:1588903958"} ! prechordal cartilage xref: FMA:52867 ! body of sphenoid xref: SCTID:140491003 ! Entire body of sphenoid bone synonym: "corpus ossis sphenoidalis" RELATED LATIN [Wikipedia:Body_of_sphenoid_bone] xref: http://upload.wikimedia.org/wikipedia/commons/d/d5/Gray146.png [Term] id: UBERON:0010355 name: ossification center def: "The first step in ossification of the cartilage is that the cartilage cells, at the point where ossification is commencing and which is termed a ossification center, enlarge and arrange themselves in rows. The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other. A deposit of calcareous material now takes place in this matrix, between the rows of cells, so that they become separated from each other by longitudinal columns of calcified matrix, presenting a granular and opaque appearance. Here and there the matrix between two cells of the same row also becomes calcified, and transverse bars of calcified substance stretch across from one calcareous column to another. Thus there are longitudinal groups of the cartilage cells enclosed in oblong cavities, the walls of which are formed of calcified matrix which cuts off all nutrition from the cells; the cells, in consequence, atrophy, leaving spaces called the primary areolC&." [Wikipedia:Ossification_center] comment: Editors note: currently classified as a zone of a bone organ, but exists prior to bone ossifying synonym: "center of ossification" RELATED [Wikipedia:Ossification_center] synonym: "centrum ossificationis" EXACT LATIN [FMA:TA] synonym: "ossification centre" EXACT [FMA:75436] is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ xref: FMA:75436 ! ossification center synonym: "centrum ossificationis" RELATED LATIN [Wikipedia:Ossification_center] xref: http://upload.wikimedia.org/wikipedia/commons/f/fd/Gray79.png [Term] id: UBERON:0010356 name: primary ossification center def: "A primary ossification center is the first area of a bone to start ossifying. It usually appears during prenatal development in the central part of each developing bone. In long bones the primary centers occur in the diaphysis/shaft and in irregular bones the primary centers occur usually in the body of the bone. Most bones have only one primary center (e.g. all long bones) but some irregular bones such as the os coxa (hip) and vertebrae have multiple primary centers." [Wikipedia:Ossification_center#Primary] synonym: "primarium" BROAD [FMA:TA] synonym: "primary ossification centre" EXACT [FMA:75447] synonym: "centrum ossificationis primarium" EXACT LATIN [NominaAnatomica:NA] is_a: UBERON:0010355 {source="FMA"} ! ossification center xref: FMA:75447 ! primary ossification center xref: ncithesaurus:Primary_Ossification_Center ! primary ossification center xref: UMLS:C1184750 [Term] id: UBERON:0010357 name: secondary ossification center def: "A secondary ossification center is the area of ossification that appears after the primary ossification center has already appeared - most of which appear during the postnatal and adolescent years. Most bones have more than one secondary ossification center. In long bones, the secondary centres appear in the epiphyses." [Wikipedia:Ossification_center#Secondary] synonym: "secondary ossification centre" EXACT [FMA:75448] synonym: "secundarium" BROAD [FMA:TA] synonym: "centrum ossificationis secundarium" EXACT LATIN [NominaAnatomica:NA] is_a: UBERON:0010355 {source="FMA"} ! ossification center xref: FMA:75448 ! secondary ossification center [Term] id: UBERON:0009637 name: alisphenoid ossification center synonym: "alisphenoid center" RELATED [] is_a: UBERON:0010355 ! ossification center [Term] id: UBERON:0010732 name: alisphenoid pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: develops_from UBERON:0007213 ! mesenchyme derived from head neural crest relationship: part_of UBERON:0009191 {source="EHDAA2"} ! sphenoid bone pre-cartilage condensation xref: EHDAA2:0003448 ! sphenoid greater wing pre-cartilage condensation synonym: "sphenoid greater wing pre-cartilage condensation" EXACT [EHDAA2:0003448] [Term] id: UBERON:0010733 ! alisphenoid cartilage condensation name: alisphenoid cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0010732 {source="EHDAA2"} ! alisphenoid pre-cartilage condensation relationship: part_of UBERON:0009193 {source="EHDAA2"} ! sphenoid bone cartilage condensation xref: EHDAA2:0003450 ! sphenoid greater wing cartilage condensation synonym: "sphenoid greater wing cartilage condensation" EXACT [EHDAA2:0003450] synonym: "alisphenoid cartilage" RELATED [] [Term] id: UBERON:0006721 name: alisphenoid bone def: "The greater wing of the sphenoid bone, or alisphenoid, is a bony process of the sphenoid bone; there is one on each side, extending from the side of the body of the sphenoid and curving upward, laterally, and backwards[WP]." [Wikipedia:Greater_wing_of_sphenoid_bone] comment: Taxon notes: The alisphenoid in mammals is part cartilage bone, part membrane bone[PMC1231738] In many mammals, e.g. the dog, the greater wing of the sphenoid bone stays through life a separate bone called the alisphenoid[WP]. Development notes: The mammalian alisphenoid forms the greater wing of the sphenoid bone, which contributes a small part of the skull vault just caudal to the orbit, and also underlies the basal part of the frontal and parietal bones in the fetus (Iseki et al. 1997)[PMID:11523816]. synonym: "greater wing of sphenoid bone" RELATED [MA:0002772] synonym: "ala major (os sphenoidale)" EXACT [FMA:52868] synonym: "greater wing of sphenoidal bone" EXACT [FMA:52868] synonym: "alisphenoid bone" EXACT SENSU [MA:0002772] synonym: "epipterygoid" RELATED SENSU [Wikipedia:Sphenoid_bone] synonym: "epipterygoid bone" RELATED SENSU [Wikipedia:Sphenoid_bone] xref: FMA:52868 ! Greater wing of sphenoid xref: MA:0002772 ! alisphenoid bone is_a: UBERON:0011164 {source="MA"} ! neurocranium bone relationship: part_of UBERON:0001677 {source="MA"} ! sphenoid bone relationship: develops_from UBERON:0009637 {source="ISBN10:1588903958"} ! alisphenoid ossification center relationship: develops_from UBERON:0010733 ! alisphenoid cartilage condensation relationship: part_of UBERON:0008895 {source="PMID:11523816"} ! splanchnocranium relationship: in_lateral_side_of UBERON:0002517 {source="FMA-abduced-lr"} ! basicranium xref: SCTID:361298007 ! Entire greater wing of sphenoid bone synonym: "ala major ossis sphenoidalis" RELATED LATIN [Wikipedia:Greater_wing_of_sphenoid_bone] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Gray145.png synonym: "greater wing of sphenoid" EXACT [FMA:52868] [Term] id: UBERON:0009638 name: orbitosphenoid ossification center synonym: "orbitosphenoid center" RELATED [] is_a: UBERON:0010355 ! ossification center comment: merge with sphenoid lesser wing cartilage condensation? [Term] id: UBERON:0010728 name: sphenoid lesser wing pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: part_of UBERON:0009191 {source="EHDAA2"} ! sphenoid bone pre-cartilage condensation xref: EHDAA2:0003449 ! sphenoid lesser wing pre-cartilage condensation [Term] id: UBERON:0005687 ! orbitosphenoid cartilage condensation name: orbitosphenoid cartilage condensation synonym: "sphenoid lesser wing cartilage condensation" RELATED [EHDAA2:0001329] xref: EHDAA2:0001329 ! orbitosphenoid cartilage xref: EHDAA:9554 ! orbitosphenoid cartilage is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0010728 {source="EHDAA2"} ! sphenoid lesser wing pre-cartilage condensation relationship: part_of UBERON:0009193 {source="EHDAA2"} ! sphenoid bone cartilage condensation [Term] id: UBERON:0002478 name: orbitosphenoid def: "One of two thin triangular plates, which arise from the upper and anterior parts of the body, and, projecting lateralward, end in sharp points." [Wikipedia:Lesser_wing_of_sphenoid_bone] subset: vertebrate_core synonym: "lesser wing of sphenoid bone" RELATED [MA:0002773] synonym: "lesser wing of sphenoid" EXACT [FMA:52869] synonym: "ala minor (os sphenoidale)" EXACT [FMA:52869] synonym: "ingrassia's process" EXACT [FMA:52869] synonym: "lesser wing of sphenoidal bone" EXACT [FMA:52869] synonym: "lesser wing of sphenoid bone" RELATED [MA:0002773] xref: AAO:0000345 ! xref: VHOG:0001153 ! orbitosphenoid xref: MA:0002773 ! orbitosphenoid xref: ZFA:0000253 ! orbitosphenoid xref: FMA:52869 ! Lesser wing of sphenoid xref: EMAPA:18719 ! orbito-sphenoid is_a: UBERON:0002513 ! endochondral bone relationship: part_of UBERON:0001677 ! sphenoid bone relationship: part_of UBERON:0003111 {source="Kardong"} ! sphenoid region relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium relationship: develops_from UBERON:0009638 ! orbitosphenoid center relationship: develops_from UBERON:0005687 ! orbitosphenoid cartilage condensation xref: SCTID:361737003 ! Entire lesser wing of sphenoid bone xref: TAO:0000253 ! orbitosphenoid synonym: "alæ parvæ" RELATED LATIN [Wikipedia:Lesser_wing_of_sphenoid_bone] xref: http://upload.wikimedia.org/wikipedia/commons/3/35/Gray145.png property_value: external_definition "Endochondral ossification of the lateral sides of the braincase.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000345", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000345", date_retrieved="2012-06-20"} property_value: external_definition "Large median unpaired cartilage bone consisting of two diverging plates. Positioned medial to the eye. The orbitosphenoid develops from the Trabeculae communis and forms the anterior and anterolateral boundary of the orbital foramen and constitutes a significant part of the sidewalls and floor of the cranial cavity. Bordered by the lateral ethmoid anteriorly, and the pterosphenoid posteriorly, The orbitosphenoid may extend ventrally to meet the parasphenoid. In the adult, the orbitosphenoid is fused ventrally to the parasphenoid via a thin sheet of bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000253", date_retrieved="2012-08-14", source="ZFIN:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: develops_from taenia marginalis anterior (TAO:0001505)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000253", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: develops_from neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000253", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: part_of neurocranium (UBERON:0001703)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000253", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps orbitosphenoid-prootic joint (TAO:0001794)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000253", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps pterosphenoid-orbitosphenoid joint (TAO:0001831)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000253", date_retrieved="2012-08-14"} property_value: axiom_lost_from_external_ontology "relationship loss: overlaps orbitosphenoid-lateral ethmoid joint (TAO:0001941)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000253", date_retrieved="2012-08-14"} synonym: "conchosphcénocïde@fr" RELATED [TAO:0000253] synonym: "orbito-sphcénocïde@fr" RELATED [TAO:0000253] relationship: in_lateral_side_of UBERON:0002517 {source="FMA-abduced-lr"} ! basicranium [Term] id: UBERON:0006722 ! manubrium of malleus name: manubrium of malleus def: "The handle of the malleus; the portion that extends downward, inward, and backward from the neck of the malleus; it is embedded throughout its length in the tympanic membrane." [http://www.mondofacto.com/facts/dictionary?manubrium+of+malleus] synonym: "handle of malleus" RELATED [MA:0002985] synonym: "malleal manubrium" RELATED [MA:0002985] synonym: "malleus handle" RELATED [MA:0002985] synonym: "malleus manubrium" RELATED [MA:0002985] synonym: "manubrium of malleus" RELATED [MA:0002985] synonym: "manubrium mallei" RELATED [MA:0002985] synonym: "malleus handle" EXACT [FMA:52760] synonym: "manubrium of malleus" EXACT [FMA:52760] xref: FMA:52760 ! Handle of malleus xref: MA:0002985 ! manubrium mallei is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001689 ! malleus relationship: surrounded_by UBERON:0002364 {source="cjm"} ! tympanic membrane xref: SCTID:264091009 ! Entire manubrium of malleus [Term] id: UBERON:0006723 name: cochlear modiolus def: "The modiolus is a conical shaped central axis in the cochlea. The Modiolus consists of spongy bone and the cochlea turns approximately 2.75 times around the modiolus The spiral ganglion is situated inside the bony modiolus." [Wikipedia:Modiolus_%28cochlea%29] synonym: "cochlea modiolus" EXACT [FMA:61278] synonym: "modiolus" BROAD [MA:0001182] synonym: "modiolus of cochlea" EXACT [FMA:61278] synonym: "columella cochleae" RELATED [BTO:0001693] xref: FMA:61278 ! Modiolus of cochlea xref: MA:0001182 ! modiolus xref: BTO:0001693 ! modiolus is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0007223 {source="MA"} ! osseus cochlea xref: ncithesaurus:Modiolus ! Modiolus xref: SCTID:361314007 ! Entire modiolus subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Gray921.png xref: UMLS:C0229503 [Term] id: UBERON:0002276 name: lamina of spiral limbus def: "The osseous spiral lamina consists of two plates of bone, and between these are the canals for the transmission of the filaments of the acoustic nerve. On the upper plate of that part of the lamina which is outside the vestibular membrane, the periosteum is thickened to form the limbus spiralis (or limbus laminæ spiralis), this ends externally in a concavity, the sulcus spiralis internus, which represents, on section, the form of the letter C. [WP,unvetted]." [Wikipedia:Limbus_laminae_spiralis] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "limbus laminae spiralis" EXACT [FMA:77721] synonym: "spiral limbus lamina" EXACT [FMA:77721] synonym: "spiral limbus lamina" EXACT [] synonym: "spiral limbus" RELATED [] synonym: "limbus lamina spiralis" EXACT [MA:0001191] xref: FMA:77721 ! Lamina of spiral limbus xref: MA:0001191 ! limbus lamina spiralis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Gray930.png/200px-Gray930.png is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001855 {source="MA"} ! cochlear duct of membranous labyrinth [Term] id: UBERON:0006724 name: osseus spiral lamina def: "The osseous spiral lamina is a bony shelf or ledge which projects from the modiolus into the interior of the canal, and, like the canal, takes two-and-three-quarter turns around the modiolus. It reaches about half-way toward the outer wall of the tube, and partially divides its cavity into two passages or scalae, of which the upper is named the scala vestibuli, while the lower is termed the scala tympani." [Wikipedia:Osseous_spiral_lamina] synonym: "lamina of modiolus cochleae" EXACT [FMA:77710] synonym: "lamina of modiolus of cochlea" EXACT [FMA:77710] synonym: "osseous spiral lamina of cochlea" EXACT [FMA:77710] synonym: "osseous spiral lamina" EXACT [] xref: FMA:77710 ! Osseous spiral lamina of cochlea xref: MA:0001184 ! osseus spiral lamina is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0007223 {source="MA"} ! osseus cochlea relationship: part_of UBERON:0006723 {source="FMA"} ! cochlear modiolus synonym: "lamina modioli cochleae" EXACT LATIN [FMA:TA, FMA:77710] [Term] id: UBERON:0006725 name: spiral ligament def: "A spiral thickening of the fibrous lining of the cochlear wall. Spiral ligament secures the membranous cochlear duct to the bony spiral canal of the cochlea. Its spiral ligament fibrocytes function in conjunction with the stria vascularis to mediate cochlear ion homeostasis." [MESH:MESH, Wikipedia:Spiral_ligament, https://sourceforge.net/tracker/?func=detail&atid=1205376&aid=3557974&group_id=76834] synonym: "spiral cochlear ligament" EXACT LATIN [] synonym: "ligamentum spirale ductus cochlearis" EXACT LATIN [Wikipedia:Spiral_ligament] synonym: "spiral ligament of cochlear duct" EXACT [FMA:77834] comment: Note that this is not classified as a ligament in FMA xref: FMA:77834 ! Spiral ligament of cochlear duct xref: MA:0001192 ! spiral ligament xref: SCTID:279840005 ! Entire spiral cochlear ligament xref: A09.246.631.246.965 is_a: UBERON:0000211 ! ligament relationship: part_of UBERON:0001855 ! cochlear duct of membranous labyrinth relationship: attaches_to UBERON:0006106 {source="MESH-def"} ! cochlear canal relationship: has_part CL:0002665 ! otic fibrocyte [Term] id: UBERON:0006727 name: liver left lateral lobe synonym: "lateral segment of liver" EXACT [FMA:14501] synonym: "segmentum laterale (lobus hepatis sinister)" EXACT [FMA:14501] synonym: "lateral segment of left lobe of liver" EXACT [FMA:14501] xref: FMA:14501 ! Lateral segment of left lobe of liver xref: MA:0001641 ! liver left lateral lobe is_a: UBERON:0001115 ! left lobe of liver xref: SCTID:271288003 ! Entire lateral segment of left lobe of liver [Term] id: UBERON:0006728 name: liver left medial lobe synonym: "medial segment of liver" EXACT [FMA:14500] synonym: "segmentum mediale (lobus hepatis sinister)" EXACT [FMA:14500] synonym: "medial segment of left lobe of liver" EXACT [FMA:14500] xref: FMA:14500 ! Medial segment of left lobe of liver xref: MA:0001642 ! liver left medial lobe is_a: UBERON:0001115 ! left lobe of liver xref: SCTID:271085007 ! Entire medial segment of left lobe of liver [Term] id: UBERON:0006729 name: liver perisinusoidal space def: "The space of Disse (or perisinusoidal space) is a location in the liver between a hepatocyte and a sinusoid. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing proteins and other plasma components from the sinusoids to be taken up by the hepatocytes. This space may be obliterated in liver disease, leading to decreased uptake by hepatocytes of nutrients and wastes (like bilirubin, for example). The Space of Disse also contains Ito cells, also called hepatic stellate cells, which store fat or fat soluble vitamins. Excessive intake of fat soluble vitamins can lead to pathologically enlarged Ito cells, which can form collagen and lead to fibrosis and cirrhosis. The Space of Disse was named after German anatomist, Joseph Disse (1852b1912)." [Wikipedia:Space_of_Disse] synonym: "perisinusoidal space" RELATED [Wikipedia:Space_of_Disse] synonym: "Disse's space" EXACT [FMA:63162] synonym: "perisinusoidal space of Disse" EXACT [FMA:63162] synonym: "perisinusoidal space" RELATED [] synonym: "space of Disse" EXACT [FMA:63162] synonym: "hepatic perisinusoidal space" EXACT [FMA:63162] xref: FMA:63162 ! Hepatic perisinusoidal space xref: MA:0002497 ! liver perisinusoidal space is_a: UBERON:0000464 ! anatomical space relationship: part_of UBERON:0004647 ! liver lobule xref: SCTID:17779003 ! Space of Disse xref: ncithesaurus:Perisinusoidal_Space ! perisinusoidal space xref: UMLS:C0227530 [Term] id: UBERON:0006743 name: paleodentate of dentate nucleus synonym: "PDT" EXACT [NIF_GrossAnatomy:birnlex_1490] synonym: "paleodentate of dentate nucleus" EXACT [NIF_GrossAnatomy:birnlex_1490] synonym: "paleodentate portion of dentate nucleus" EXACT [FMA:72540] xref: FMA:72540 ! paleodentate part of dentate nucleus xref: NIF_GrossAnatomy:birnlex_1490 ! Paleodentate of dentate nucleus is_a: UBERON:0002020 ! gray matter of neuraxis is_a: UBERON:0002946 ! regional part of cerebellum relationship: part_of UBERON:0002132 ! dentate nucleus synonym: "paleodentate part of dentate nucleus" EXACT [FMA:72540] [Term] id: UBERON:0006801 alt_id: UBERON:3000835 name: proximal head of humerus def: "Hemispherical structure on proximal epiphysis of humerus that articulates with glenoid cavity[WP,modified]." [Wikipedia:Upper_extremity_of_humerus#Humeral_head] synonym: "humeral head" RELATED [FMA:13304, PHENOSCAPE:curators] synonym: "head of humerus" EXACT [FMA:13304] synonym: "caput humeri" RELATED [AAO:0000835, Wikipedia:Upper_extremity_of_humerus#Humeral_head] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004411 ! proximal epiphysis of humerus relationship: connected_to UBERON:0006657 ! glenoid fossa relationship: overlaps UBERON:0001470 ! glenohumeral joint xref: FMA:13304 ! head of humerus xref: AAO:0000835 ! glenoid head xref: EMAPA:25050 ! head xref: ncithesaurus:Head_of_the_Humerus xref: galen:HeadOfHumerus xref: SCTID:181924000 ! Entire head of humerus property_value: external_definition "Hemispherical ball on the proximal end of the humerus that fits into the glenoid cavity of the pectoral girdle to form the shoulder joint[AAO]." xsd:string {ontology="AAO", external_class="AAO:0000835", source="AAO:LAP"} xref: UMLS:C0223683 [Term] id: UBERON:0012129 name: radial head of humerus def: "Hemispherical ball located at the lower end of the humerus that stands out prominently from the surrounding structures toward the flexor surface of the forelimb" [PHENOSCAPE:curators, AAO:LAP] synonym: "eminentia capitata" RELATED [AAO:0000838] synonym: "radial condyle" RELATED [AAO:0000838] synonym: "radial condyle of humerus" EXACT [] synonym: "capitellum of humerus" EXACT [] synonym: "capitellum" RELATED [] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004404 ! distal epiphysis of humerus xref: AAO:0000838 ! humeral head property_value: external_definition "Hemispherical ball located at the lower end of the humerus that stands out prominently from the surrounding structures toward the flexor surface of the forelimb and fits into the socket joint of the olecranon process[AAO]." xsd:string {ontology="AAO", external_class="AAO:0000838", source="AAO:LAP"} [Term] id: UBERON:0012130 name: olecranon fossa def: "Above the back part of the trochlea of the humerus is a deep triangular depression, the olecranon fossa, in which the summit of the olecranon is received in extension of the forearm." [Wikipedia:Olecranon_fossa] comment: a deep evacuation in the bone, into which the anconeal process of the ulna passes when the elbow joint is extended synonym: "fossa olecrani" EXACT LATIN [Wikipedia:Olecranon_fossa] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004404 ! distal epiphysis of humerus xref: FMA:23450 ! olecranon fossa [Term] id: UBERON:0006802 name: acetabular rim def: "A prominent unever rim that bounds the acetabulum, serving as the attachment for the acetabular labrum, which reduces its opening, and deepens the surface for formation of the hip joint." [http://en.wikipedia.org/wiki/Acetabulum#Structure] synonym: "acetabular margin" RELATED [] xref: FMA:16941 ! Acetabular rim is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001269 ! acetabular part of hip bone [Term] id: UBERON:0011958 name: acetabular labrum def: "A ring of cartilage that surrounds the acetabulum[WP,unvetted]." [Wikipedia:Acetabular_labrum] comment: Function notes: Its function is to deepen the acetabulum, making it more difficult for the head of the femur to slip out of place (sublux). Structure notes: some sources treat this as fibrocartilage synonym: "labrum of acetabulum" EXACT [FMA:43521] synonym: "glenoidal labrum of hip joint" RELATED [Wikipedia:Acetabular_labrum] synonym: "cotyloid ligament" RELATED [Wikipedia:Acetabular_labrum] synonym: "labrum acetabuli" EXACT LATIN [Wikipedia:Acetabular_labrum] synonym: "acetabular rim" RELATED INCONSISTENT [AAO:0000864] synonym: "acetabular lip" RELATED [] is_a: UBERON:0007844 {source="FMA"} ! cartilage element relationship: part_of UBERON:0001486 {source="FMA"} ! hip joint relationship: attaches_to UBERON:0006802 ! acetabular rim relationship: surrounds UBERON:0001269 ! acetabular part of hip bone xref: FMA:43521 ! acetabular labrum xref: SCTID:182439007 ! Entire labrum of acetabulum xref: SCTID:263366005 ! Lip of acetabulum xref: AAO:0000864 ! acetabular rim property_value: external_definition "Cartilaginous ring that forms the entire acetabular margin[AAO:0000864]." xsd:string {source="AAO:0000864", notes="AAO class treated as equivalent to labrum based on this definition"} [Term] id: UBERON:0006803 name: obturator foramen def: "The obturator foramen is the hole created by the ischium and pubis bones of the pelvis through which nerves and muscles pass." [Wikipedia:Obturator_foramen] synonym: "foramen obturatorium" EXACT LATIN [FMA:16999] xref: AAO:0000863 ! obturator foramen xref: FMA:16999 ! Obturator foramen is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0007832 {source="AAO"} ! pelvic girdle skeleton xref: ncithesaurus:Obturator_Foramen ! Obturator Foramen xref: SCTID:361777006 ! Entire obturator foramen synonym: "foramen obturatum" RELATED LATIN [Wikipedia:Obturator_foramen] xref: http://upload.wikimedia.org/wikipedia/commons/f/ff/Skeletpelvis-pubis.jpg property_value: external_definition "Small opening for the passage of the obturatorius nerve that perforates the pubis.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000863", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass pelvic girdle opening (AAO:0000767)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000863", date_retrieved="2012-06-20"} xref: UMLS:C0223670 [Term] id: UBERON:0006804 name: reticular tissue def: "Loose connective tissue which consists of an irregular network of cells and reticular fibers and is spatially associated with myeloid and lymphoid cells. Examples: stroma of bone marrow, stroma of spleen, stroma of lymph node.[FMA]" [FMA:20116, FMA:FMA, Wikipedia:Reticular_connective_tissue] comment: AO notes: in FMA this is asserted as part of smooth muscle tissue synonym: "reticular connective tissue" EXACT [FMA:20116] synonym: "textus connectivus reticularis" EXACT LATIN [FMA:20116] xref: AAO:0000542 ! reticular connective tissue xref: FMA:20116 ! Reticular tissue is_a: UBERON:0011825 {source="FMA"} ! loose connective tissue relationship: has_part GO:0005586 ! collagen type III xref: SCTID:57987007 ! Reticular tissue property_value: external_definition "Network of reticular fibres (fine collagen) that form a soft skeleton to support the lymphoid organs (lymph nodes, bone marrow, and spleen).[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000542", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000542", date_retrieved="2012-06-20"} [Term] id: UBERON:0011895 name: endomysium def: "A layer of connective tissue that ensheaths a muscle fiber and is composed mostly from reticular fibers. It also contains capillaries, nerves and lymphatics. The term cardiac skeleton is sometimes considered synonymous with endomysium, but sometimes it refers to the combination of the endomysium and perimysium." [Wikipedia:Endomysium] synonym: "fascia of muscle fiber" EXACT [FMA:9729] intersection_of: UBERON:0006804 ! reticular tissue intersection_of: surrounds CL:0000187 ! muscle cell relationship: part_of UBERON:0002385 ! muscle tissue xref: FMA:9729 ! endomysium xref: ncithesaurus:Endomysium ! endomysium xref: SCTID:91739007 ! Endomysium xref: UMLS:C0504097 [Term] id: UBERON:0011896 name: smooth muscle endomysium def: "Reticular tissue which surrounds a smooth muscle cell." [UBERON:cjm] intersection_of: UBERON:0011895 ! endomysium intersection_of: part_of UBERON:0001135 ! smooth muscle tissue relationship: surrounds CL:0000192 ! smooth muscle cell xref: FMA:260651 ! Smooth muscle endomysium [Term] id: UBERON:0011897 name: cardiac endomysium def: "Reticular tissue which surrounds a cardiac myocyte." [FMA:83112] synonym: "Endomysium of cardiac muscle cell" EXACT [FMA:83112] synonym: "Fibrocollagenous sheath of cardiac muscle cell" EXACT [FMA:83112] intersection_of: UBERON:0011895 ! endomysium intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue relationship: surrounds CL:0000746 ! cardiac muscle cell xref: FMA:83112 ! Cardiac endomysium [Term] id: UBERON:0011898 name: skeletal muscle endomysium def: "Reticular tissue which surrounds a skeletal muscle cell." [FMA:86022] intersection_of: UBERON:0011895 ! endomysium intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: surrounds CL:0000188 ! skeletal muscle cell xref: FMA:86022 ! Skeletal muscle endomysium [Term] id: UBERON:0011899 name: epimysium def: "Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. The Epimysium also protects muscles from friction against other muscles and bones." [Wikipedia:Epimysium] synonym: "epimysia" RELATED PLURAL [Wikipedia:Epimysium] synonym: "fascia of muscle organ" EXACT [FMA:9726] is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue relationship: part_of UBERON:0001134 {source="FMA"} ! skeletal muscle tissue relationship: surrounds UBERON:0001630 ! muscle organ xref: FMA:9726 ! epimysium xref: ncithesaurus:Epimysium ! epimysium xref: UMLS:C0504096 [Term] id: UBERON:0011900 name: perimysium def: "The fibrous sheath enveloping each of the primary bundles of skeletal muscle fibers." [Wikipedia:Perimysium, http://medical-dictionary.thefreedictionary.com/perimysium] synonym: "fascia of muscle fasciculus" EXACT [FMA:9728] is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue relationship: part_of UBERON:0001134 {source="FMA"} ! skeletal muscle tissue xref: FMA:9728 ! perimysium xref: ncithesaurus:Perimysium ! perimysium xref: SCTID:63406008 ! Perimysium xref: UMLS:C0224087 [Term] id: UBERON:0006805 name: sternal end of clavicle def: "Medial end of the clavicle, which usually lies on the ventral side of the epicoracoid cartilage, just posterior to the epicoracoid bridge." [AAO:0000812] synonym: "extremitas sternalis (Clavicula)" EXACT [FMA:23297] synonym: "medial end of clavicle" EXACT [FMA:23297] synonym: "extremitas medialis" RELATED [AAO:0000812] synonym: "medial end" RELATED [AAO:0000812] xref: AAO:0000812 ! sternal end of clavicle xref: FMA:23297 ! Sternal end of clavicle is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001105 ! clavicle xref: SCTID:181920009 ! Entire sternal end of clavicle [Term] id: UBERON:0010853 name: capitulum of humerus def: "In human anatomy of the arm, the lateral portion of the articular surface of the humerus consists of a smooth, rounded eminence, named the capitulum of the humerus. It articulates with the cupshaped depression on the head of the radius, and is limited to the front and lower part of the bone.." [Wikipedia:Capitulum_of_the_humerus] comment: TODO - check AAO. Taxon notes: In birds, where forelimb anatomy has adaptation for flight, its functional if not ontogenetic equivalent is the dorsal condyle of the humerus[WP] synonym: "capitellum" RELATED [Wikipedia:Capitulum_of_the_humerus] synonym: "capitulum of humerus" RELATED [Wikipedia:Capitulum_of_the_humerus] synonym: "dorsal condyle of the humerus" RELATED SENSU [Wikipedia:Capitulum_of_the_humerus] synonym: "humeral capitulum" EXACT [FMA:23373] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0009988 {source="FMA"} ! condyle of humerus xref: FMA:23373 ! capitulum of humerus synonym: "capitulum humeri" RELATED LATIN [Wikipedia:Capitulum_of_the_humerus] xref: http://upload.wikimedia.org/wikipedia/commons/b/b9/Capitulumhumeri.PNG xref: SCTID:282816008 ! Entire capitulum of humerus [Term] id: UBERON:0009979 ! condyle name: condyle def: "the round prominence at the end of a bone, most often part of a joint - an articulation with another bone[WP]." [Wikipedia:Condyle_(anatomy)] is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ xref: SCTID:91737009 ! Entire condyle xref: ncithesaurus:Condyle ! Condyle xref: FMA:75434 ! Condyle xref: TAO:0002259 ! condyle property_value: external_definition "Protuberance on a bone that participates in a joint with another bone.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002259", date_retrieved="2012-08-14", source="TAO:wd"} xref: galen:Condyle ! condyle property_value: has_relational_adjective "condylar" xsd:string xref: UMLS:C0524414 [Term] id: UBERON:0009988 name: condyle of humerus def: "the distal end of the humerus, including the trochlea, capitulum and the olecranon, coronoid and radial fossae" [http://www.medilexicon.com/medicaldictionary.php?t=19715] synonym: "condylus humeri" EXACT [] intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0004404 ! distal epiphysis of humerus xref: SCTID:361778001 ! Entire condyle of humerus xref: FMA:23377 ! Condyle of humerus synonym: "humeral condyle" EXACT [FMA:23377] [Term] id: UBERON:0009989 ! condyle of tibia name: condyle of tibia def: "One of the lateral or medial condyles of the tibia." [Wikipedia:Tibial_condyle] synonym: "tibial condyle" EXACT [AAO:0000899] intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0008772 ! proximal epiphysis of tibia xref: SCTID:182062002 ! Entire condyle of tibia xref: AAO:0000899 ! tibial condyle property_value: external_definition "Convex articular facet of the distal head of the femur that articulates with the proximal head of the tibia.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000899", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0009980 ! condyle of femur name: condyle of femur synonym: "femoral condyle" EXACT [] synonym: "condylus femoralis" EXACT [] synonym: "condylus femoris" EXACT [] synonym: "fibular condyle" RELATED [AAO:0000900] intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0004406 ! distal epiphysis of femur xref: AAO:0000900 ! fibular condyle xref: FMA:32855 ! Condyle of femur property_value: external_definition "Convex articular facet of the distal head of the femur that articulates with the proximal head of the fibula.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000900", date_retrieved="2012-06-20", source="AAO:LAP"} xref: SCTID:304912006 ! Condyle of femur xref: galen:FemoralCondyle ! femoral condyle def: "A condyle that is part of a distal epiphysis of femur." [OBOL:automatic] [Term] id: UBERON:0009984 name: medial condyle of femur def: "The medial condyle is one of the two projections on the lower extremity of femur. The medial condyle is larger than the lateral (outer) condyle due to more weight bearing caused by the center of gravity being medial to the knee. On the posterior surface of the condyle the linea aspera (a ridge running down the posterior shaft of the femur) turns into the medial supracondylar ridge. The outermost protrusion on the medial surface of the medial condyle is referred to as the \"medial epicondyle\" and can be palpated by running fingers medially from the patella with the knee in flexion." [Wikipedia:Medial_condyle_of_femur] synonym: "medial condyle of the femur" RELATED [Wikipedia:Medial_condyle_of_femur] synonym: "c. medialis femoris" RELATED [Wikipedia:Medial_condyle_of_femur] is_a: UBERON:0009980 ! condyle of femur relationship: part_of UBERON:0004406 {source="FMA"} ! distal epiphysis of femur xref: FMA:32858 ! medial condyle of femur xref: SCTID:182056007 ! Entire medial condyle of femur synonym: "c. medialis femoris" RELATED LATIN [Wikipedia:Medial_condyle_of_femur] xref: http://upload.wikimedia.org/wikipedia/commons/5/53/Gray246.png [Term] id: UBERON:0009985 name: lateral condyle of femur def: "The lateral condyle is one of the two projections on the lower extremity of femur. It is the more prominent and is the broader both in its antero-posterior and transverse diameters" [Wikipedia:Lateral_condyle_of_femur] synonym: "lateral condyle of the femur" RELATED [Wikipedia:Lateral_condyle_of_femur] synonym: "c. lateralis femoris" RELATED [Wikipedia:Lateral_condyle_of_femur] is_a: UBERON:0009980 ! condyle of femur relationship: part_of UBERON:0004406 {source="FMA"} ! distal epiphysis of femur xref: FMA:32859 ! lateral condyle of femur xref: SCTID:182057003 ! Entire lateral condyle of femur synonym: "c. lateralis femoris" RELATED LATIN [Wikipedia:Lateral_condyle_of_femur] xref: http://upload.wikimedia.org/wikipedia/commons/5/53/Gray246.png [Term] id: UBERON:0009990 name: medial condyle of tibia def: "The medial condyle is the medial portion of the upper extremity of tibia. It is the site of insertion for the Semimembranosus muscle[WP]." [Wikipedia:Medial_condyle_of_tibia] synonym: "condylus medialis (tibia)" EXACT [FMA:35445] synonym: "medial condyle of the tibia" RELATED [Wikipedia:Medial_condyle_of_tibia] synonym: "medial tibial condyle" RELATED [Wikipedia:Medial_condyle_of_tibia] is_a: UBERON:0009989 ! condyle of tibia xref: FMA:35445 ! medial condyle of tibia xref: SCTID:182066004 ! Entire medial condyle of tibia synonym: "c. medialis tibiae" RELATED LATIN [Wikipedia:Medial_condyle_of_tibia] xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray257.png xref: galen:MedialTibialCondyle ! medial tibial condyle [Term] id: UBERON:0009991 name: lateral condyle of tibia def: "The lateral condyle is the lateral portion of the upper extremity of tibia. It serves as the insertion for the Biceps femoris muscle[WP]." [Wikipedia:Lateral_condyle_of_tibia] synonym: "condylus lateralis (tibia)" EXACT [FMA:35448] is_a: UBERON:0009989 ! condyle of tibia xref: FMA:35448 ! lateral condyle of tibia xref: SCTID:182067008 ! Entire lateral condyle of tibia synonym: "c. lateralis tibiae" RELATED LATIN [Wikipedia:Lateral_condyle_of_tibia] xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray257.png [Term] id: UBERON:0009978 name: epicondyle def: "." [Wikipedia:Epicondyle] comment: grouping class that collected the ect- and ep- icondyles of humerus and femur is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ subset: grouping_class xref: FMA:75435 ! epicondyle xref: SCTID:333209006 ! Entire epicondyle xref: ncithesaurus:Epicondyle ! Epicondyle synonym: "epicondylus" RELATED LATIN [Wikipedia:Epicondyle] property_value: has_relational_adjective "epicondylar" xsd:string xref: galen:Epicondyle ! epicondyle xref: UMLS:C0222681 [Term] id: UBERON:0006806 name: entepicondyle of humerus def: "A bony projection on the distal epiphysis of the humerus that is the attachment site for the flexor muscles of the manus. This condyle faces posteriorly (for sprawling tetrapods) or medially (for erect tetrapods)." [Wikipedia:Medial_epicondyle_of_the_humerus, http://palaeos.com/vertebrates/glossary/glossaryE.html, PHENOSCAPE:ad] synonym: "elbow pit" RELATED [Wikipedia:Medial_epicondyle_of_the_humerus] synonym: "epicondylus medialis (humerus)" RELATED [FMA:23441] synonym: "epicondylus medialis humeri" RELATED [AAO:0000782] synonym: "medial epicondyle" BROAD [AAO:0000782] synonym: "entepicondyle" EXACT [PHENOSCAPE:pm] synonym: "ulnar condyle of humerus" RELATED [http://www.termiumplus.gc.ca] synonym: "ventral epicondyle of humerus" RELATED SENSU [Wikipedia:Medial_epicondyle_of_the_humerus] synonym: "medial epicondyle of humerus" RELATED HUMAN_PREFERRED [FMA:23441] synonym: "e. medialis humeri" RELATED LATIN [Wikipedia:Medial_epicondyle_of_the_humerus] xref: AAO:0000782 ! medial epicondyle xref: FMA:23441 ! medial epicondyle of humerus is_a: UBERON:0009978 {source="FMA"} ! epicondyle relationship: part_of UBERON:0004404 {source="FMA"} ! distal epiphysis of humerus xref: SCTID:181929005 ! Entire medial epicondyle of humerus xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray329-Medial_epicondyle_of_the_humerus.png xref: http://palaeos.com/vertebrates/glossary/images/172x202xentepicondyleA1.gif.pagespeed.ic.EoVgrHaVyX.png property_value: external_definition "Rounded projection at the distal head of the humerus and medial to the humeral head, which serves as a place of attachment for the flexor muscles antogonistic to those that attach to the lateral epicondyle.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000782", date_retrieved="2012-06-20", source="AAO:LAP"} xref: galen:MedialHumeralEpicondyle ! medial humeral epicondyle property_value: has_relational_adjective "entepicondylar" xsd:string [Term] id: UBERON:0013207 name: entepicondylar foramen def: "The entepicondylar foramen is an opening in the distal (far) end of the humerus (upper arm bone) present in some mammals. It is often present in primitive placentals, such as the enigmatic Madagascan Plesiorycteropus. In most Neotominae and all Tylomyinae among cricetid rodents, it is located above the medial epicondyle of the humerus, but it is absent in all Sigmodontinae and Arvicolinae and this trait has been suggested as a synapomorphy for the former subfamily." [Wikipedia:Entepicondylar_foramen] is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0004404 ! distal epiphysis of humerus [Term] id: UBERON:0006807 name: ectepicondyle of humerus def: "A bony projection on the distal epiphysis of the humerus that is the attachment site for the extensor muscles of the distal parts of the forelimb. In humans, this is known as the lateral epicondyle, but the position varies across tetrapods." [Wikipedia:Lateral_epicondyle_of_the_humerus, PMID:15064415, http://palaeos.com/vertebrates/glossary/glossaryE.html, PHENOSCAPE:ad] synonym: "epicondylus lateralis (humerus)" EXACT [FMA:23442] synonym: "epicondylus lateralis humeri" RELATED [AAO:0000758] synonym: "dorsal epicondyle of the humerus" RELATED SENSU [Wikipedia:Lateral_epicondyle_of_the_humerus] synonym: "lateral epicondyle of humerus" RELATED HUMAN_PREFERRED [FMA:23442] synonym: "dorsal epicondyle of humerus" RELATED [Wikipedia:Lateral_epicondyle_of_the_humerus, NCBITaxon:8782] synonym: "lateral epicondyle" BROAD [AAO:0000758] synonym: "ectepicondyle" BROAD [PMID:15064415] synonym: "e. lateralis humeri" RELATED LATIN [Wikipedia:Lateral_epicondyle_of_the_humerus] xref: AAO:0000758 ! lateral epicondyle xref: FMA:23442 ! lateral epicondyle of humerus is_a: UBERON:0009978 {source="FMA"} ! epicondyle relationship: part_of UBERON:0004404 {source="FMA"} ! distal epiphysis of humerus xref: SCTID:181933003 ! Entire lateral epicondyle of humerus xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Gray420.png property_value: external_definition "Rounded projection at the distal head of the humerus (larger and more prominent than the lateral epicondyle) and lateral to the humeral head, which serves as a place of attachment for the mm extensor antebrachii et carpi radialis, extensor digitorum communis, and in part to the m extensor antebrachii et carpi ulnaris.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000758", date_retrieved="2012-06-20", source="AAO:LAP"} xref: galen:LateralHumeralEpicondyle ! lateral humeral epicondyle [Term] id: UBERON:0009986 name: lateral epicondyle of femur def: "The lateral epicondyle of the femur, smaller and less prominent than the medial epicondyle, gives attachment to the fibular collateral ligament of the knee-joint. Directly below it is a small depression from which a smooth well-marked groove curves obliquely upward and backward to the posterior extremity of the condyle." [Wikipedia:Lateral_epicondyle_of_the_femur] synonym: "lateral femoral epicondyle" RELATED [Wikipedia:Lateral_epicondyle_of_the_femur] synonym: "epicondylus lateralis (femur)" EXACT [FMA:32867] is_a: UBERON:0009978 {source="FMA"} ! epicondyle relationship: part_of UBERON:0004406 {source="FMA"} ! distal epiphysis of femur relationship: part_of UBERON:0009985 {source="FMA"} ! lateral condyle of femur xref: FMA:32867 ! lateral epicondyle of femur xref: SCTID:209275007 ! Entire lateral epicondyle of femur synonym: "e. lateralis femoris" RELATED LATIN [Wikipedia:Lateral_epicondyle_of_the_femur] xref: http://upload.wikimedia.org/wikipedia/commons/5/53/Gray246.png xref: galen:LateralFemoralEpicondyle ! lateral femoral epicondyle [Term] id: UBERON:0009987 name: medial epicondyle of femur def: "The medial epicondyle of the femur is a bony protrusion located on the medial side of the bone's distal end. Located above the medial condyle, it bears an elevation, the adductor tubercle, which serves for the attachment of the superficial part, or \"tendinous insertion\", of the adductor magnus. This tendinous part here forms an intermuscular septum which forms the medial separation between the thigh's flexors and extensors. Behind it, and proximally to the medial condyle is a rough impression which gives origin to the medial head of the Gastrocnemius." [Wikipedia:Medial_epicondyle_of_the_femur] synonym: "medial femoral epicondyle" RELATED [Wikipedia:Medial_epicondyle_of_the_femur] synonym: "epicondylus medialis (femur)" EXACT [FMA:32864] is_a: UBERON:0009978 {source="FMA"} ! epicondyle relationship: part_of UBERON:0004406 {source="FMA"} ! distal epiphysis of femur relationship: part_of UBERON:0009984 {source="FMA"} ! medial condyle of femur xref: FMA:32864 ! medial epicondyle of femur xref: SCTID:209172001 ! Entire medial epicondyle of femur synonym: "epicondylus medialis femoris" RELATED LATIN [Wikipedia:Medial_epicondyle_of_the_femur] xref: http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray345.png xref: galen:MedialFemoralEpicondyle ! medial femoral epicondyle [Term] id: UBERON:0006809 name: obsolete supporting connective tissue def: "Specialized connective tissue is a connective tissue, which consists of osteocytes and chondrocytes, the intercellular matrix of which is chondrified or calcified.[FMA]" [FMA:37374, FMA:FMA] comment: made obsolete because FMA:37374 is a General anatomical term rather than a true class in the FMA synonym: "specialized connective tissue" EXACT [FMA:37374] consider: AAO:0000571 ! specialized connective tissue consider: FMA:37374 ! Supporting connective tissue is_obsolete: true [Term] id: UBERON:0006822 ! proximal epiphysis of ulna name: proximal epiphysis of ulna def: "The head of ulna presents an articular surface, part of which, of an oval or semilunar form, is directed downward, and articulates with the upper surface of the triangular articular disk which separates it from the wrist-joint; the remaining portion, directed lateralward, is narrow, convex, and received into the ulnar notch of the radius." [Wikipedia:Head_of_ulna] synonym: "head of ulna" EXACT [FMA:33751] synonym: "proximal end of ulna" EXACT [FMA:33751] synonym: "upper end of ulna" EXACT [FMA:33751] xref: FMA:33751 ! proximal epiphysis of ulna intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001424 ! ulna synonym: "caput ulnae" EXACT LATIN [FMA:TA, FMA:33751] xref: galen:HeadOfUlna xref: SCTID:304590006 ! Entire proximal end of ulna synonym: "caput ulnae" RELATED LATIN [Wikipedia:Head_of_ulna] [Term] id: UBERON:0006810 name: olecranon def: "The olecranon is a large, thick, curved bony eminence of the forearm that projects behind the elbow. It is situated at the upper (proximal) end of the ulna, one of the two bones in the forearm. When the hand faces forward the olecranon faces towards the back (posteriorly). It is bent forward at the summit so as to present a prominent lip which is received into the olecranon fossa of the humerus in extension of the forearm. Its base is contracted where it joins the body and the narrowest part of the upper end of the ulna. Its posterior surface, directed backward, is triangular, smooth, subcutaneous, and covered by a bursa. Its superior surface is of quadrilateral form, marked behind by a rough impression for the insertion of the Triceps brachii; and in front, near the margin, by a slight transverse groove for the attachment of part of the posterior ligament of the elbow-joint. Its anterior surface is smooth, concave, and forms the upper part of the semilunar notch. Its borders present continuations of the groove on the margin of the superior surface; they serve for the attachment of ligaments, viz. , the back part of the ulnar collateral ligament medially, and the posterior ligament laterally. From the medial border a part of the Flexor carpi ulnaris arises; while to the lateral border the anconeus muscle is attached." [Wikipedia:Olecranon] comment: Check AAO synonym: "olecranon process of ulna" EXACT [Wikipedia:Olecranon] synonym: "olecranon process" RELATED [Wikipedia:Olecranon] synonym: "ulnar process" RELATED [AAO:0000843] xref: AAO:0000843 ! olecranon xref: FMA:39795 ! Olecranon is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0006822 ! proximal epiphysis of ulna xref: ncithesaurus:Olecranon ! Olecranon xref: SCTID:181949001 ! Entire olecranon xref: http://upload.wikimedia.org/wikipedia/commons/6/60/Gray212.png property_value: external_definition "Large and thick process situated at the proximal (upper) end of the ulna. Its inner face forms the medial articular surface that articulates with the humeral head.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000843", date_retrieved="2012-06-20", source="AAO:LAP"} xref: UMLS:C0223710 [Term] id: UBERON:0006811 name: occipital condyle def: "The occipital condyles are undersurface facets of the occipital bone in vertebrates, which function in articulation with the superior facets of the atlas vertebra. The condyles are oval or reniform (kidney-shaped) in shape, and their anterior extremities, directed forward and medialward, are closer together than their posterior, and encroach on the basilar portion of the bone; the posterior extremities extend back to the level of the middle of the foramen magnum. The articular surfaces of the condyles are convex from before backward and from side to side, and look downward and lateralward. To their margins are attached the capsules of the atlantoC6ccipital articulations, and on the medial side of each is a rough impression or tubercle for the alar ligament. At the base of either condyle the bone is tunnelled by a short canal, the hypoglossal canal." [Wikipedia:Occipital_condyle, Wikipedia:Exoccipital_condyle] comment: birds have a single occipital condyle, mammals have two[WP] xref: AAO:0000330 ! occipital condyle xref: FMA:52861 ! Occipital condyle synonym: "exoccipital condyle" RELATED [Wikipedia:Exoccipital_condyle] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001693 ! exoccipital bone synonym: "condylus occipitalis" RELATED LATIN [Wikipedia:Occipital_condyle] xref: http://upload.wikimedia.org/wikipedia/commons/8/88/Gray129.png [Term] id: UBERON:0006812 name: mental foramen def: "The mental foramen is one of two holes (\"foramina\") located on the anterior surface of the mandible. It permits passage of the mental nerve and vessels. The mental foramen descends slightly in edentulous individuals." [Wikipedia:Mental_foramen] synonym: "foramen mentalis" RELATED [Wikipedia:Mental_foramen] synonym: "mental foramina" EXACT PLURAL [OBOL:automatic] xref: AAO:0000298 ! mental foramen xref: FMA:53171 ! Mental foramen is_a: UBERON:0005744 {source="FMA"} ! cranial conduit relationship: located_in UBERON:0001684 ! mandible xref: SCTID:244686000 ! Mental foramen synonym: "foramen mentale" RELATED LATIN [Wikipedia:Mental_foramen] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png [Term] id: UBERON:0006813 name: nasal skeleton def: "Structural framework that provides support to the nasal sacs and ducts." [AAO:0000320] synonym: "skeleton of nose" EXACT [FMA:60116] xref: AAO:0000320 ! nasal skeleton xref: FMA:60116 ! Nasal skeleton is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: subdivision_of UBERON:0000004 ! olfactory apparatus relationship: part_of UBERON:0000004 {source="FMA"} ! olfactory apparatus relationship: part_of UBERON:0003113 {source="Kardong-abduced", notes="facial series"} ! dermatocranium relationship: part_of UBERON:0011156 ! facial skeleton xref: SCTID:281486007 ! Entire nasal skeleton [Term] id: UBERON:0011167 name: septomaxilla bone def: "Paired, intramembranous bones located within the nasal capsules and embedded in the nasal cartilages; it is pierced by the ductus nasolacrimalis." [AAO:0000556] comment: A small dermal bone of the facial series that is often absent; when present it is usually sunken beneath the surface bones and aids in forming the nasal cavity synonym: "internasale" RELATED [AAO:0000556] synonym: "intranasal" RELATED [AAO:0000556] synonym: "lacrimale" RELATED [AAO:0000556] synonym: "le cornet" RELATED [AAO:0000556] synonym: "nariale" RELATED [AAO:0000556] synonym: "nasale" RELATED [AAO:0000556] synonym: "os internasale" RELATED [AAO:0000556] synonym: "os nariale" RELATED [AAO:0000556] synonym: "septomaxillary" RELATED [AAO:0000556] synonym: "turbinale" RELATED [AAO:0000556] synonym: "septomaxilla" EXACT [AAO:0000556] is_a: UBERON:0002514 ! intramembranous bone relationship: part_of UBERON:0006813 {source="AAO"} ! nasal skeleton xref: AAO:0000556 ! septomaxilla [Term] id: UBERON:0006815 name: areolar connective tissue def: "Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand.[FMA]" [FMA:63897, FMA:FMA] synonym: "loose connective tissue" RELATED [AAO:0000027] synonym: "loose areolar connective tissue" EXACT [FMA:63897] xref: AAO:0000027 ! areolar connective tissue xref: FMA:63897 ! Areolar connective tissue is_a: UBERON:0011825 {source="FMA"} ! loose connective tissue relationship: part_of UBERON:0000030 ! lamina propria relationship: has_part CL:1000303 {source="FMA"} ! fibroblast of areolar connective tissue xref: SCTID:68477002 ! Loose areolar connective tissue property_value: external_definition "Also known as loose connective tissue. A pliable, mesh-like tissue with a fluid matrix that functions to cushion and protect body organs.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000027", date_retrieved="2012-06-20", source="AAO:LAP"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000027", date_retrieved="2012-06-20"} [Term] id: UBERON:0006820 name: body of sternum def: "The body of the sternum (gladiolus), considerably lengthier, narrower, and thinner than the manubrium, attains its greatest breadth close to the lower end." [Wikipedia:Body_of_sternum] comment: AAO - Proximal portion of the sternum, usually elaborated into a stylum that may be ossified. [AAO:0000939] synonym: "body of the sternum" RELATED [Wikipedia:Body_of_sternum] synonym: "gladiolus of sternum" EXACT [FMA:7487] synonym: "mesosternum" EXACT [FMA:7487] synonym: "sternal body" EXACT [FMA:7487] xref: AAO:0000939 ! mesosternum xref: FMA:7487 ! Body of sternum is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000975 ! sternum xref: SCTID:361743001 ! Entire body of sternum synonym: "corpus sterni" RELATED LATIN [Wikipedia:Body_of_sternum] xref: http://upload.wikimedia.org/wikipedia/commons/2/23/Gray116.png property_value: external_definition "Proximal portion of the sternum, usually elaborated into a stylum that may be ossified.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000939", date_retrieved="2012-06-20", source="AAO:LAP"} [Term] id: UBERON:0011604 ! carina of sternum name: carina of sternum def: "An extension of the sternum (breastbone) which runs axially along the midline of the sternum and extends outward, perpendicular to the plane of the ribs[WP]." [Wikipedia:Keel_(bird)] synonym: "keel" BROAD [] synonym: "carina" BROAD [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000975 ! sternum relationship: only_in_taxon NCBITaxon:8782 {source="Wikipedia"} ! Aves relationship: has_function_in GO:0060361 ! flight disjoint_from: UBERON:0006679 ! carina of trachea xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/69/Br%C3%A9chet.png/180px-Br%C3%A9chet.png [Term] id: UBERON:0011605 name: supracoracoideus def: "'A muscle in the bird's thorax region that originates from carina of the sternum, furcula, and sternal ribs and inserts onto proximal dorsal surface of the humerus. It acts as a primary elevator of the wing in upstroke. [Manual of Ornithology: Avian Structure and Function, by Proctor and Lynch, 1998]." [ID:KFC0000604] synonym: "pectoralis minor" RELATED [ID:KFC0000604] is_a: UBERON:0008196 ! muscle of pectoral girdle relationship: has_muscle_origin UBERON:0011604 ! carina of sternum relationship: has_muscle_origin UBERON:0007841 ! furcula relationship: has_muscle_origin UBERON:0002228 ! rib relationship: has_muscle_insertion UBERON:0000976 ! humerus xref: http://upload.wikimedia.org/wikipedia/commons/0/02/Wing_Muscles%2C_color.svg [Term] id: UBERON:0006821 name: cutaneous muscle xref: AAO:0000119 ! cutaneous muscles xref: FMA:74996 ! Cutaneous muscle is_a: UBERON:0002385 ! muscle tissue relationship: part_of UBERON:0001774 ! muscle of trunk xref: ncithesaurus:Cutaneous_Muscle ! Cutaneous Muscle xref: UMLS:C1184459 [Term] id: UBERON:0006837 name: tegmen tympani def: "The Tegmental Wall or Roof (paries tegmentalis) is formed by a thin plate of bone, the tegmen tympani, which separates the cranial and tympanic cavities. It is situated on the anterior surface of the petrous portion of the temporal bone close to its angle of junction with the squama temporalis; it is prolonged backward so as to roof in the tympanic antrum, and forward to cover in the semicanal for the Tensor tympani muscle. Its lateral edge corresponds with the remains of the petrosquamous suture[Grays] ." [http://education.yahoo.com/reference/gray/subjects/subject/230] comment: todo - check AAO; grouping is made on basis of related synonym. Crista parotica: seems to be the same as the crista prootica. However, since this lateral ridge of the otic capsule is frequently formed by the opisthotic, rather than the prootic, this may be a better name.; Crista prootica: a ledge or ridge which elaborates the dorsal surface of the prootic or, more generally, the roof of the otic capsule, laterally. The crista may extend posteriorly & laterally, continuous with the paroccipital process, and/or anteriorly or anteroventrally to protect cranial nerve foramina and form part of the fenestra ovalis/vestibuli. In basal tetrapodomorphs and tetrapods, the crista prootica forms the floor of the posttemporal fenestra. See The Prootic. In many tetrapods, the crista prootica is not ossified, or incompletely ossified. However, in frogs, the crista is the main strut joining the skull roofing bones (frontoparietals) with the squamosals. The crista prootica has a similarly expanded role in mammals where it forms an important part of the epitympanic recess and anchors the tympanohyal.[http://www.palaeos.com] subset: dubious_grouping synonym: "tegmental roof of tympanic cavity" EXACT [FMA:56002] synonym: "tegmental wall of tympanic cavity" EXACT [FMA:56002] synonym: "processus muscularis capsulae auditivae" RELATED [AAO:0000116] synonym: "processus squamosus" RELATED HOMOLOGY [AAO:0000116] synonym: "crista parotica" RELATED HOMOLOGY [AAO:0000116] synonym: "crista prootica" RELATED HOMOLOGY [AAO:0000116, http://www.palaeos.com/Vertebrates/Lists/Glossary/GlossaryCr.html] xref: AAO:0000116 ! crista parotica xref: FMA:56002 ! Tegmen tympani is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001756 ! middle ear synonym: "paries tegmentalis cavi tympani" EXACT LATIN [FMA:TA, FMA:56002] [Term] id: UBERON:0006838 name: anterior ramus of spinal nerve def: "The ventral ramus (anterior ramus, anterior branch, anterior divisions of the spinal nerves) supply the antero-lateral parts of the trunk, and the limbs; they are for the most part larger than the posterior divisions. In the thoracic region they remain distinct from each other and each innervates a narrow strip of muscle and skin along the sides, chest, ribs, and abdominal wall. These rami are called the intercostal nerves. In regions other than the thoracic, ventral rami converge with each other to form networks of nerves called nerve plexuses. Within each plexus, fibers from the various ventral rami branch and become redistributed so that each nerve exiting the plexus has fibers from several different spinal nerves. One advantage to having plexuses is that damage to a single spinal nerve will not completely paralyze a limb. There are four main plexuses formed by the ventral rami: The cervical plexus contains ventral rami from spinal nerves C1-C5. Branches of the cervical plexus, which include the phrenic nerve, innervate muscles of the neck, the diaphragm, and the skin of the neck and upper chest. The brachial plexus contains ventral rami from spinal nerves C5-T1. This plexus innervates the pectoral girdle and upper limb. The lumbar plexus contains ventral rami from spinal nerves L1-L4. The sacral plexus contains ventral rami from spinal nerves L4-S4. The lumbar and sacral plexuses innervate the pelvic girdle and lower limbs. The Ventral rami, including the sinuvertebral nerve branches, supply structures anterior to the facet joint, including the vertebral bodies, the discs and their ligaments and joints other spinal nerves to form the lumbo-sacral plexus." [Wikipedia:Anterior_ramus_of_spinal_nerve] synonym: "anterior primary ramus of spinal nerve" EXACT [FMA:5982] synonym: "ramus anterior" BROAD [FMA:5982] synonym: "ventral ramus of spinal nerve" EXACT [FMA:5982] xref: FMA:5982 ! Anterior ramus of spinal nerve is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0005476 ! spinal nerve trunk relationship: part_of UBERON:0001780 ! spinal nerve synonym: "ramus anterior nervi spinalis" RELATED LATIN [Wikipedia:Anterior_ramus_of_spinal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg [Term] id: UBERON:0006839 name: posterior ramus of spinal nerve def: "The posterior (or dorsal) branches (or divisions) of the spinal nerves are as a rule smaller than the anterior divisions. They are also referred to as the dorsal rami. They are directed backward, and, with the exceptions of those of the first cervical, the fourth and fifth sacral, and the coccygeal, divide into medial and lateral branches for the supply of the muscles and skin of the posterior part of the trunk. Shortly after a spinal nerve exits the intervertebral foramen, it branches into the dorsal ramus, ventral ramus, and rami communicantes. Each of these latter three structures carries both sensory and motor information. Because each spinal nerve carries both sensory and motor information, spinal nerves are referred to as bmixed nerves. b Dorsal rami carry visceral motor, somatic motor, and sensory information to and from the skin and muscles of the back. Dorsal rami remain distinct from each other, and each innervates a narrow strip of skin and muscle along the back, more or less at the level from which the ramus leaves the spinal nerve. The smaller, posteriorly-directed major terminal branch (with the ventral primary ramus) of all 31 pairs of mixed spinal nerves, formed at the intervertebral foramen and turning abruptly posteriorly to divide into lateral and medial branches, both of which will supply the deep (true) muscles of the back. The medial branch (rami medialis) of the dorsal primary ramus also supplies articular branches to the zygopophyseal joints and the periosteum of the vertebral arch. In the neck and upper back, the medial branch continues through the deep and superficial back muscles to supply overlying skin; in the lower back, the lateral branch does this. Nomina Anatomica lists dorsal primary rami as \"rami dorsales\" for each group of spinal nerves: 1) cervical (nervorum cervicalium), 2) thoracic (nervorum thoracicorum), 3) lumbar (nervorum lumbalium), 4) sacral (nervorum sacralium), and 5) coccygeal (nervi coccygei). Synonyms: ramus dorsalis nervorum spinalium, ramus dorsalis, rami posteriores nervorum spinalium, dorsal branch, posterior primary division." [Wikipedia:Posterior_ramus_of_spinal_nerve] synonym: "dorsal ramus" EXACT [FMA:5983] synonym: "dorsal ramus of spinal nerve" EXACT [FMA:5983] synonym: "posterior primary ramus" EXACT [FMA:5983] synonym: "ramus posterior" BROAD [FMA:5983] xref: FMA:5983 ! Posterior ramus of spinal nerve is_a: UBERON:0001021 ! nerve relationship: branch_of UBERON:0005476 ! spinal nerve trunk relationship: part_of UBERON:0001780 ! spinal nerve xref: AAO:0010800 ! ramus dorsal synonym: "ramus posterior nervi spinalis" RELATED LATIN [Wikipedia:Posterior_ramus_of_spinal_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray819.png property_value: external_definition "A thin ramus which branches from the common trunk of the PLLN when it separates from the postotic ganglionic complex. It turns dorsally and extends over the trunk and dorsal fin innervating the dorsal line of neuromasts.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010800", date_retrieved="2012-06-20", source="AAO:SIQ"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass posterior lateral line nerve (PLLN) (AAO:0010115)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010800", date_retrieved="2012-06-20"} [Term] id: UBERON:0006841 name: central vein of liver def: "Vein that is central to a lobule in the liver." [ZFA:0005168] subset: vertebrate_core synonym: "terminal branch of hepatic vein" EXACT [FMA:17544] synonym: "terminal hepatic venule" EXACT [FMA:17544] synonym: "vena centralis (Hepar)" EXACT [FMA:17544] xref: ZFA:0005168 ! central vein xref: FMA:17544 ! Central vein of liver is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0004647 ! liver lobule xref: SCTID:272023004 ! Entire central vein of liver xref: TAO:0005168 ! central vein [Term] id: UBERON:0010523 name: microcirculatory vessel def: "A portion of tissue that consists of a tube composed of epithelial cells that connects larger vessels." [ZFA:0005251] synonym: "microcirculatory vessels" RELATED PLURAL [TAO:0005251] xref: TAO:0005251 ! microcirculatory vessels is_a: UBERON:0000055 ! vessel relationship: part_of UBERON:0002049 {source="ZFA"} ! vasculature xref: ZFA:0005251 ! microcirculatory vessel [Term] id: UBERON:0006842 name: lymphatic capillary def: "Microvessel of the lymphatic system lined with a single layer of overlapping endothelial cells. Joins to form the lymphatic vessels." [ZFA:0005252] comment: todo - check superclass subset: vertebrate_core synonym: "lymph capillary" EXACT [FMA:5028] xref: ZFA:0005252 ! lymphatic capillary xref: FMA:5028 ! Lymphatic capillary is_a: UBERON:0010523 {source="ZFA"} ! microcirculatory vessel is_a: UBERON:0001473 {source="FMA"} ! lymphatic vessel relationship: part_of UBERON:0004536 ! lymph vasculature xref: ncithesaurus:Lymphatic_Capillary ! Lymphatic Capillary xref: TAO:0005252 ! lymphatic capillary property_value: external_definition "Microvessel of the lymphatic system lined with a single layer of overlapping endothelial cells.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005252", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: UMLS:C0162405 [Term] id: UBERON:0006843 name: root of cranial nerve subset: vertebrate_core comment: Editor note: recommend asserting under this class rather than relying on inference, as relations may change synonym: "cranial nerve root" EXACT [FMA:52609] synonym: "cranial neural root" EXACT [FMA:52609] xref: ZFA:0001663 ! cranial nerve root xref: FMA:52609 ! Root of cranial nerve intersection_of: UBERON:0002211 ! nerve root intersection_of: continuous_with UBERON:0001785 ! cranial nerve xref: SCTID:280161004 ! Cranial nerve root xref: TAO:0002190 ! cranial nerve root def: "A nerve root that continuous_with a cranial nerve." [OBOL:automatic] [Term] id: UBERON:0006844 name: cusp of tooth comment: This class may be obsoleted and split - the TAO class is generic, the mammalian class refers specifically to a molariform tooth subset: vertebrate_core synonym: "tooth cusp" EXACT [FMA:56481] synonym: "cusp" BROAD [] synonym: "tooth cone" RELATED [ISBN10:0073040584] xref: ZFA:0005434 ! tooth cusp xref: FMA:56481 ! Cusp of tooth is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: part_of UBERON:0003675 {source="FMA"} ! tooth crown xref: SCTID:362107000 ! Entire cusp of tooth xref: ncithesaurus:Tooth_Cusp ! tooth cusp xref: TAO:0001973 ! tooth cusp property_value: external_definition "Anatomical structure that is a natural outgrowth, prominence, or point that is part of the surface of a tooth.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001973", date_retrieved="2012-08-14", source="TAO:wd"} property_value: external_definition "the elevated, somewhat pointed portions of the chewing surfaces on premolar and molar teeth" xsd:string {date_retrieved="2012-09-28", source="http://anthro.palomar.edu/primate/glossary.htm"} xref: UMLS:C0226994 [Term] id: UBERON:0007115 name: deciduous tooth def: "One of the first set of teeth in the growth development of humans and many other mammals[WP]. The 20 teeth of the first dentition, which are shed and replaced by the permanent teeth, usually by the age of six years. All deciduous teeth are normally expected to erupt by the age of two and a half years[MESH]." [MESH:A14.254.860.700, Wikipedia:Deciduous_teeth] comment: GAT in FMA. synonym: "temporary tooth" EXACT [FMA:55655] synonym: "primary tooth" EXACT [FMA:55655] xref: MESH:A14.254.860.700 xref: GAID:1266 ! deciduous tooth xref: FMA:55655 ! primary tooth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: part_of UBERON:0007116 ! primary dentition xref: ncithesaurus:Temporary_Tooth ! Temporary Tooth xref: SCTID:245612004 ! Entire deciduous tooth synonym: "dentes decidui" RELATED LATIN [Wikipedia:Deciduous_teeth] xref: http://upload.wikimedia.org/wikipedia/commons/9/97/Deciduous_teeth_by_David_Shankbone.jpg xref: UMLS:C0040455 [Term] id: UBERON:0007775 name: secondary tooth def: "Permanent teeth are the second set of teeth formed in humans[WP]." [Wikipedia:Permanent_teeth] comment: GAT in FMA synonym: "permanent tooth" EXACT [FMA:55654] xref: FMA:55654 ! secondary tooth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: part_of UBERON:0007774 ! secondary dentition xref: ncithesaurus:Permanent_Tooth ! Permanent Tooth xref: SCTID:245563006 ! Entire permanent tooth synonym: "dentes permanentes" RELATED LATIN [Wikipedia:Permanent_teeth] xref: http://upload.wikimedia.org/wikipedia/commons/1/14/Teeth_by_David_Shankbone.jpg xref: UMLS:C0348070 [Term] id: UBERON:0007776 name: unerupted tooth def: "A normal developing tooth which has not yet perforated the oral mucosa or one that fails to erupt in the normal sequence or time interval expected for the type of tooth in a given gender, age, or population group." [MESH:A14.254.860.715] synonym: "unerupted teeth" RELATED [GAID:1268] xref: MESH:A14.254.860.715 xref: GAID:1268 ! unerupted tooth is_a: UBERON:0001091 ! calcareous tooth [Term] id: UBERON:0009977 name: natal tooth def: "Predeciduous teeth present at birth. They may be well formed and normal or may represent hornified epithelial structures without roots. They are found on the gingivae over the crest of the ridge and arise from accessory buds of the dental lamina ahead of the deciduous buds or from buds of the accessory dental lamina. (From Jablonski, Dictionary of Dentistry, 1992)" [MESH:A14.254.860.700.500] synonym: "natal tooth" RELATED [GAID:1267] xref: MESH:A14.254.860.700.500 is_a: UBERON:0007115 {source="GAID"} ! deciduous tooth xref: GAID:1267 ! natal teeth synonym: "natal teeth" EXACT PLURAL [GAID:1267] [Term] id: UBERON:0007116 ! primary dentition name: primary dentition def: "The set of teeth first in order or time of development that will be replaced by permanent dentition upon their loss." [MESH:A14.254.245] synonym: "baby teeth" EXACT [FMA:75151] synonym: "primary teeth" EXACT [GAID:1266] synonym: "deciduous teeth" EXACT [FMA:75151] synonym: "milk teeth" EXACT [FMA:75151] synonym: "primary teeth" EXACT [FMA:75151] synonym: "set of deciduous teeth" EXACT [FMA:75151] synonym: "set of primary teeth" EXACT [FMA:75151] synonym: "deciduous dentition" RELATED [GAID:1252] synonym: "tooth of primary dentition" EXACT [] xref: FMA:75151 ! primary dentition xref: MESH:A14.254.245 xref: GAID:1252 ! primary dentition is_a: UBERON:0003672 ! dentition synonym: "dentes decidui" EXACT LATIN [FMA:TA, FMA:75151] [Term] id: UBERON:0007774 ! secondary dentition name: secondary dentition def: "The teeth of adulthood that either replace or are added to the complement of deciduous teeth. (Boucher's Clinical Dental Terminology, 4th ed)" [MESH:A14.254.237] synonym: "adult dentition" RELATED [GAID:1251] synonym: "secondary dentition" RELATED [GAID:1251] synonym: "permanent teeth" EXACT [FMA:75152] synonym: "set of permanent teeth" EXACT [FMA:75152] synonym: "set of secondary teeth" EXACT [FMA:75152] synonym: "permanent dentition" EXACT [GAID:1251] xref: FMA:75152 ! secondary dentition xref: MESH:A14.254.237 xref: GAID:1251 ! permanent dentition is_a: UBERON:0003672 {source="FMA"} ! dentition intersection_of: UBERON:0003672 ! dentition intersection_of: developmentally_replaces UBERON:0007116 ! primary dentition synonym: "dentes permanentes" EXACT LATIN [FMA:TA, FMA:75152] [Term] id: UBERON:0007799 name: mixed dentition def: "The complement of teeth in the jaws after the eruption of some of the permanent teeth but before all the deciduous teeth are absent. (Boucher's Clinical Dental Terminology, 4th ed)" [MESH:A14.254.229] synonym: "transitional dentition" EXACT [GAID:1250] xref: MESH:A14.254.229 xref: GAID:1250 ! mixed dentition is_a: UBERON:0003672 {source="GAID"} ! dentition xref: SCTID:245545006 ! Mixed dentition [Term] id: UBERON:0006845 name: abductor muscle def: "A muscle that moves a body part away from the sagittal plane/midline of the body[ZFA]. For example, the abductor muscles of the legs spread the legs away from the midline and away from one another. An abductor muscle opposes an adductor muscle[BTO]." [ZFA:0005269] comment: note that in FMA the Adbuctor muscle is a subclass of Relation. It's unclear what this actually means, we leave it here as a grouping for now subset: grouping_class xref: ZFA:0005269 ! abductor muscle xref: FMA:74997 ! Abductor muscle xref: BTO:0004642 ! abductor is_a: UBERON:0001134 ! skeletal muscle tissue xref: TAO:0002135 ! abductor muscle property_value: external_definition "A muscle that moves a body part away from the sagittal plane of the body.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002135", date_retrieved="2012-08-14", source="ZFA:curator"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass cranial muscle (TAO:0001953)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002135", date_retrieved="2012-08-14"} [Term] id: UBERON:0006846 ! groove name: groove def: "Anatomical line that delineates a furrow or depression in an organ or tissue." [ZFA:0001690] subset: grouping_class xref: ZFA:0001690 ! groove xref: FMA:75037 ! Groove xref: EHDAA2:0003161 ! groove xref: AEO:0000161 ! groove is_a: UBERON:0006800 ! anatomical line xref: AAO:0010276 ! groove xref: TAO:0001838 ! groove [Term] id: UBERON:0012079 name: metapterygial axis def: "proximodistal trajectory through a metapterygium[Wagner]" [] comment: persisted in sacropterygians, precursor to limb axis is_a: UBERON:0006800 ! anatomical line [Term] id: UBERON:0006847 name: cerebellar commissure subset: vertebrate_core synonym: "commissura cerebelli" EXACT [ZFA:0000490] xref: ZFA:0000490 ! commissura cerebelli xref: FMA:77522 ! Cerebellar commissure is_a: UBERON:0001020 ! commissure is_a: UBERON:0002317 ! white matter of cerebellum xref: TAO:0000490 ! commissura cerebelli [Term] id: UBERON:0006848 name: posterior pretectal nucleus def: "Diencephalic nucleus that is part of the superficial pretectum and is rostrally contiguous with the magnocellular superficial pretectal nucleus. Cells of the caudal pretectal nucleus are slightly smaller and less orderly around a central neuropil than those of the magnocellular superficial pretectal nucleus. From Neuroanatomy of the Zebrafish Brain." [ZFA:0000631] subset: dubious_grouping subset: vertebrate_core synonym: "caudal pretectal nuclei" EXACT [ZFA:0000631] synonym: "posterior pretectal nucleus" EXACT [ZFA:0000631] xref: ZFA:0000631 ! caudal pretectal nucleus xref: FMA:84355 ! posterior pretectal nucleus xref: ABA:PPT ! Posterior pretectal nucleus is_a: UBERON:0006569 ! diencephalic nucleus relationship: spatially_disjoint_from UBERON:0002996 {source="ABA"} ! nucleus of optic tract relationship: spatially_disjoint_from UBERON:0002711 {source="ABA"} ! nucleus of posterior commissure relationship: spatially_disjoint_from UBERON:0002565 {source="ABA"} ! olivary pretectal nucleus xref: TAO:0000631 ! caudal pretectal nucleus [Term] id: UBERON:0006851 name: renal cortex peritubular capillary xref: MA:0002590 ! renal cortex peritubular capillary intersection_of: UBERON:0005272 ! peritubular capillary intersection_of: part_of UBERON:0001225 ! cortex of kidney synonym: "kidney cortex peritubular capillary" EXACT [MA:0002590] def: "A peritubular capillary that is part of a cortex of kidney." [OBOL:automatic] [Term] id: UBERON:0006852 name: glomerular visceral epithelium synonym: "podocyte layer" RELATED [MA:0002607] xref: MA:0002607 ! glomerular visceral epithelium xref: EMAPA:28254 ! visceral epithelium of glomerular tuft is_a: UBERON:0004188 ! glomerular epithelium relationship: part_of UBERON:0000074 ! renal glomerulus [Term] id: UBERON:0006853 name: renal cortex tubule xref: MA:0002609 ! renal cortex tubule xref: EMAPA:18976 ! cortical renal tubule intersection_of: UBERON:0007685 ! region of renal tubule intersection_of: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney synonym: "kidney cortex tubule" EXACT [MA:0002609] synonym: "cortical tubule" RELATED [MA:0002609] def: "A region of nephron tubule that is part of a cortex of kidney." [OBOL:automatic] [Term] id: UBERON:0006376 name: premacula segment of distal straight tubule def: "." [https://sourceforge.net/tracker/?func=detail&aid=3123600&group_id=76834&atid=1205376, PMID:14595018] synonym: "renal medulla thick ascending limb" EXACT [MA:th] synonym: "renal medulla loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "kidney medulla loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "medullary thick ascending limb of Henle's loop" EXACT [MA:th] xref: MA:0002628 ! distal straight tubule premacula segment xref: EMAPA:28331 ! premacula segment of distal straight tubule of loop of Henle, outer medullary portion xref: EMAPA:29683 ! premacula segment of distal straight tubule of loop of Henle of inner stripe of outer medulla xref: EMAPA:31379 ! premacula segment of distal straight tubule of distal straight tubule of renal distal tubule is_a: UBERON:0007685 ! region of nephron tubule relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle relationship: part_of UBERON:0006541 {source="MA"} ! outer medulla inner stripe loop of henle relationship: part_of UBERON:0006542 {source="MA"} ! outer medulla outer stripe loop of henle synonym: "distal straight tubule premacula segment" EXACT [MA:0002628] [Term] id: UBERON:0006854 name: distal straight tubule postmacula segment def: "." [https://sourceforge.net/tracker/?func=detail&aid=3123598&group_id=76834&atid=1205376] synonym: "renal cortex thick ascending limb" EXACT [MA:th] synonym: "renal cortex loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "kidney cortex loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "cortical thick ascending limb of Henle's loop" EXACT [MA:th] xref: MA:0002615 ! distal straight tubule postmacula segment xref: EMAPA:28402 ! postmacula segment is_a: UBERON:0007685 ! region of nephron tubule relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle relationship: part_of UBERON:0006853 {source="MA"} ! renal cortex tubule [Term] id: UBERON:0000060 alt_id: UBERON:0009915 name: anatomical wall def: "Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers." [FMA:82482] comment: AO notes: in FMA, serosa is a wall subset: upper_level synonym: "wall" EXACT [] xref: galen:Wall ! wall xref: EMAPA:25036 ! wall xref: FMA:82482 ! wall of organ synonym: "wall of organ" EXACT [FMA:82482] is_a: UBERON:0000061 ! anatomical structure relationship: adjacent_to UBERON:0002553 ! anatomical cavity relationship: has_part UBERON:0004923 ! organ component layer synonym: "organ wall" RELATED [FMA:82482] [Term] id: UBERON:0009916 name: wall of ureter synonym: "ureteral wall" EXACT [FMA:15888] intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000056 ! ureter xref: FMA:15888 ! wall of ureter xref: SCTID:279397004 ! Wall of ureter def: "An anatomical wall that is part of a ureter." [OBOL:automatic] [Term] id: UBERON:0006855 ! ureter muscle layer name: ureter muscle layer xref: MA:0002654 ! ureter muscle layer xref: FMA:15893 ! muscular layer of ureter xref: SCTID:3563003 ! Muscularis of ureter xref: EMAPA:28567 ! middle layer synonym: "ureteral smooth muscle layer" RELATED [EMAPA:28567] synonym: "muscular layer of ureter" EXACT [FMA:15893] synonym: "muscular coat of ureter" EXACT [FMA:15893] synonym: "muscularis of ureter" EXACT [FMA:15893] synonym: "tunica muscularis (ureter)" EXACT LATIN [FMA:TA] synonym: "tunica muscularis ureteris" EXACT LATIN [FMA:TA] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0009916 {source="FMA"} ! wall of ureter def: "A muscle layer that is part of a ureter." [OBOL:automatic] [Term] id: UBERON:0006869 ! electric organ name: electric organ def: "A specialized tract of tissue (as in the electric eel) in which electricity is generated." [BTO:0000376, Wikipedia:Electric_organ] comment: todo - request go term for function assignment; todo - add CL term for electrocyte // modified muscle or nerve cells, which became specialized for producing bioelectric fields stronger than those that normal nerves or muscles produce (Albert and Crampton, 2006) xref: GAID:1210 ! electric organ xref: MESH:A13.332 ! electric organ is_a: UBERON:0000062 ! organ relationship: only_in_taxon NCBITaxon:7898 ! Actinopterygii xref: TAO:0002037 ! electric organ property_value: external_definition "Organ that is used to produce an electric field, i.e. an electric organ discharge (EOD).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002037", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0011287 name: rostral organ def: "A putative electroreceptor organ located in the medial rostral cavity in the ethmoid portion of the chondrocranium of Coelocanths. It is surrounded by an insulating layer of adipose tissue and innervated by the superficial ophthalmic nerve." [Wikipedia:Rostral_organ] comment: classification as electric organ is putative is_a: UBERON:0006869 ! electric organ relationship: part_of UBERON:0011241 ! ethmoid region relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0010519 name: tail electric organ synonym: "electric organ of tail" EXACT [] intersection_of: UBERON:0006869 ! electric organ intersection_of: part_of UBERON:0002415 ! tail relationship: part_of UBERON:0002415 {source="BTO"} ! tail xref: BTO:0000376 ! electric organ def: "An electric organ that is part of a tail." [OBOL:automatic] [Term] id: UBERON:0010520 name: head electric organ comment: Taxon notes: electric ray intersection_of: UBERON:0006869 ! electric organ intersection_of: part_of UBERON:0000033 ! head def: "An electric organ that is part of a head." [OBOL:automatic] [Term] id: UBERON:0006870 name: endostyle def: "An endostyle is a longitudinal ciliated groove on the ventral wall of the pharynx which produces mucus to gather food particles. It is found in urochordates and cephalochordates, and in the larvae of lampreys. It aids in transporting food to the esophagus. It is also called the hypopharyngeal groove. The endostyle in larval lampreys (ammocetes) metamorphoses into the thyroid gland in adults, and is regarded as being homologous to the thyroid gland in vertebrates. However, Dumont, et al. question whether the endostyle in ammocetes is homologous with that of the urochordates and cephalochordates. Since the endostyle is found in the three branches of chordates, it is presumed to have arisen in the common ancestor of these taxa, along with a shift to internal feeding for extracting suspended food from the water." [Wikipedia:Endostyle] comment: Dumont, et al. question whether the endostyle in ammocetes is homologous with that of the urochordates and cephalochordates[WP]. synonym: "hypopharyngeal groove" RELATED [BTO:0003173] xref: BTO:0003173 ! endostyle xref: ANISEED:1235299 ! Endostyle is_a: UBERON:0006846 ! groove relationship: part_of UBERON:0006562 ! pharynx relationship: only_in_taxon NCBITaxon:7711 {source="Wikipedia:Endostyle"} ! Chordata relationship: part_of UBERON:0000949 {source="http://webs.lander.edu/rsfox/invertebrates/ammocoetes.html"} ! endocrine system relationship: develops_into UBERON:0002046 ! thyroid gland [Term] id: UBERON:0006909 name: lumen of gut synonym: "gut lumen" EXACT [FMA:45677] synonym: "lumen of digestive tract" EXACT [UBERON:cjm] synonym: "lumen of alimentary tract" EXACT [UBERON:cjm] synonym: "digestive tract lumen" EXACT [UBERON:cjm] synonym: "gut cavity" EXACT [BTO:0000349] xref: FMA:45677 ! lumen of gut xref: BTO:0000349 ! gut cavity intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract def: "An anatomical space that surrounded_by a digestive tract." [OBOL:automatic] [Term] id: UBERON:0006911 name: digestive system fluid or secretion xref: MA:0002512 ! digestive system fluid or secretion xref: BTO:0000346 ! digestive juice is_a: UBERON:0000463 ! portion of organism substance relationship: secreted_by UBERON:0001007 ! digestive system [Term] id: UBERON:0007113 ! venom name: venom def: "Poisonous animal secretions forming fluid mixtures of many different enzymes, toxins, and other substances. These substances are produced in specialized glands and secreted through specialized delivery systems (nematocysts, spines, fangs, etc.) for disabling prey or predator." [MESH:A12.200.935, Wikipedia:Venom] comment: Note we include a separate class for snake venom synonym: "zootoxin" RELATED [MESH:Wikipedia:Venom] subset: grouping_class xref: MESH:A12.200.935 ! venom xref: BTO:0001439 ! venom is_a: UBERON:0000456 ! bodily secretion [Term] id: UBERON:0011579 name: venom gland def: "A gland that secretes venom." [UBERON:cjm] comment: Note we include a separate class for snake venom glands subset: functional_classification intersection_of: UBERON:0002365 ! exocrine gland intersection_of: secretes UBERON:0007113 ! venom relationship: present_in_taxon NCBITaxon:6656 ! Arthropoda relationship: present_in_taxon NCBITaxon:7898 ! Actinopterygii relationship: present_in_taxon NCBITaxon:8314 ! Salamandridae relationship: present_in_taxon NCBITaxon:9257 ! Ornithorhynchus xref: SCTID:362181001 ! Entire venom gland [Term] id: UBERON:0011580 name: platypus crural gland def: "A kidney-shaped alveolar glands located in the upper thigh connected by a thin-walled duct to a calcaneus spur, or calcar, on each hind lim" [Wikipedia:Platypus_venom#Spur_and_crural_gland] is_a: UBERON:0002365 ! exocrine gland relationship: secretes UBERON:0007113 ! venom relationship: part_of UBERON:0011581 ! calcaneus spur relationship: only_in_taxon NCBITaxon:9257 ! Ornithorhynchus [Term] id: UBERON:0011581 name: platypus calcaneus spur comment: Taxon notes: The female platypus, in common with echidnas, has rudimentary spur buds which do not develop (dropping off before the end of their first year) and lack functional crural glands. Not to be confused with 'calcaneal spur', a small osteophyte (bone spur) located on the calcaneus (heel bone) synonym: "calcaneus spur" RELATED [] synonym: "ankle spur" RELATED [] synonym: "poisonous ankle spur" RELATED [] synonym: "hind-leg spur" RELATED [] is_a: UBERON:0002529 ! limb segment relationship: part_of UBERON:0002387 ! pes relationship: present_in_taxon NCBITaxon:9257 ! Ornithorhynchus [Term] id: UBERON:0008976 ! snake venom gland name: snake venom gland def: "The venom gland of snakes is in actual fact a modified salivary gland and is linked to the groove in the fangs by a duct." [BTO:0001440] comment: snake venom glands are modified salivary glands. In future this class may be merged into a more general modified salivary gland venom gland class is_a: UBERON:0002365 {source="BTO"} ! exocrine gland relationship: homologous_to UBERON:0001044 {source="BTO-modified"} ! salivary gland relationship: only_in_taxon NCBITaxon:8570 {source="ISBN10:0073040584"} ! Serpentes relationship: secretes UBERON:0013076 ! snake venom synonym: "poison gland" RELATED [BTO:0001440] synonym: "venom gland" BROAD [BTO:0001440] synonym: "venenosalivary gland" RELATED [] property_value: has_relational_adjective "venenosalivary" xsd:string xref: BTO:0001440 ! venom gland xref: SCTID:23993002 ! Venenosalivary gland structure [Term] id: UBERON:0013075 name: venom gland duct synonym: "duct of venom gland" EXACT [] xref: SCTID:38124005 ! Venom gland duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0011579 ! venom gland [Term] id: UBERON:0013076 name: snake venom def: "Solutions or mixtures of toxic and nontoxic substances elaborated by snake (Ophidia) salivary glands for the purpose of killing prey or disabling predators and delivered by grooved or hollow fangs. They usually contain enzymes, toxins, and other factors." [MESH:D24.185.965.850, Wikipedia:Snake_venom] synonym: "venenosalivary venom" RELATED [] intersection_of: UBERON:0007113 ! venom intersection_of: secreted_by UBERON:0008976 ! snake venom gland relationship: homologous_to UBERON:0001836 ! saliva xref: MESH:D24.185.965.850 ! snake venom [Term] id: UBERON:0013078 name: venom-injecting tooth def: "A fang that is used to inject venom into prey, through either a tube or a groove" [UBERON:cjm] is_a: UBERON:0001091 ! calcareous tooth synonym: "fang" RELATED [] synonym: "tubular tooth" RELATED [] synonym: "tubular fang" RELATED [] synonym: "grooved fang" RELATED [] [Term] id: UBERON:0013106 name: elapid venom def: "Venoms from snakes of the family Elapidae, including cobras, kraits, mambas, coral, tiger, and Australian snakes. The venoms contain polypeptide toxins of various kinds, cytolytic, hemolytic, and neurotoxic factors, but fewer enzymes than viper or crotalid venoms. Many of the toxins have been characterized." [MESH:D24.185.965.850.325] synonym: "elapid venom" RELATED [MESH:D24.185.965.850.325] is_a: UBERON:0013076 {source="MESH"} ! snake venom xref: MESH:D24.185.965.850.325 ! elapid venom [Term] id: UBERON:0013110 name: hydrophid venom def: "Venoms of sea snakes, Hydrophiinae, found around Pacific islands. The venoms contain fewer enzymes and more neuro- or myotoxins than land snakes. The neurotoxic proteins are similar to elapid small, short, or type I neurotoxins, some of which have been characterized." [MESH:D24.185.965.850.480] synonym: "hydrophid venom" RELATED [MESH:D24.185.965.850.480] synonym: "sea snake venom" RELATED [MESH:D24.185.965.850.480] is_a: UBERON:0013076 {source="MESH"} ! snake venom xref: MESH:D24.185.965.850.480 ! hydrophid venom [Term] id: UBERON:0013112 name: viper venom def: "Venoms from snakes of the viperid family. They tend to be less toxic than elapid or hydrophid venoms and act mainly on the vascular system, interfering with coagulation and capillary membrane integrity and are highly cytotoxic. They contain large amounts of several enzymes, other factors, and some toxins." [MESH:D24.185.965.850.960] synonym: "cerastes venom" RELATED [MESH:D24.185.965.850.960] synonym: "egyptian sand viper venom" RELATED [MESH:D24.185.965.850.960] synonym: "viper venom" RELATED [MESH:D24.185.965.850.960] synonym: "viperotoxin" RELATED [MESH:D24.185.965.850.960] is_a: UBERON:0013076 {source="MESH"} ! snake venom xref: MESH:D24.185.965.850.960 ! viper venom [Term] id: UBERON:0013114 name: compressor glandulae muscle comment: only found in crotaline snakes, and has a spotty distribution within that group is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0013116 ! venom gland musculature relationship: attaches_to UBERON:0004768 ! bone of lower jaw relationship: attaches_to UBERON:0008976 ! snake venom gland [Term] id: UBERON:0013115 name: pterygoideus glandulae muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0013116 ! venom gland musculature [Term] id: UBERON:0013116 ! venom gland musculature name: venom gland musculature is_a: UBERON:0001015 ! musculature relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0006913 name: lip epithelium xref: BTO:0004468 ! lip epithelium xref: ZFA:0005334 ! lip epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001833 ! lip xref: TAO:0005334 ! lip epithelium property_value: external_definition "The thick, high squamous-stratified epithelium that covers the lips. It contains abundant melanocytes, many mucous cells and has well differentiated taste buds.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005334", date_retrieved="2012-08-14", source="ZFIN:ZDB-PUB-060921-12"} def: "An epithelium that is part of a lip." [OBOL:automatic] [Term] id: UBERON:0006958 name: great vein of heart def: "The Great Cardiac Vein (left coronary vein) begins at the apex of the heart and ascends along the anterior longitudinal sulcus to the base of the ventricles. It then curves to the left in the coronary sulcus, and reaching the back of the heart, opens into the left extremity of the coronary sinus. It receives tributaries from the left atrium and from both ventricles: one, the left marginal vein, is of considerable size, and ascends along the left margin of the heart." [Wikipedia:Great_cardiac_vein] synonym: "great cardiac vein" EXACT [FMA:4707] synonym: "vena cordis magna" RELATED LATIN [Wikipedia:Great_cardiac_vein] synonym: "vena cardiaca magna" RELATED LATIN [Wikipedia:Great_cardiac_vein] xref: FMA:4707 ! Great cardiac vein xref: MA:0002131 ! great vein of heart is_a: UBERON:0004148 ! cardiac vein relationship: in_left_side_of UBERON:0000948 ! heart xref: ncithesaurus:Great_Cardiac_Vein ! Great Cardiac Vein xref: SCTID:277728005 ! Entire great cardiac vein xref: EHDAA2:0004508 ! great cardiac vein xref: http://upload.wikimedia.org/wikipedia/commons/5/57/Gray556.png xref: UMLS:C0226659 [Term] id: UBERON:0006959 name: mandible angular process def: "a process which protrudes from the ventral caudal angle of the mandible, and acts as the attachment of the digastric muscle." [http://medical-dictionary.thefreedictionary.com/mandibular+angular+process] synonym: "mandibular angle" RELATED [MA:0002873] xref: MA:0002873 ! mandible angular process is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0001684 ! mandible [Term] id: UBERON:0011345 name: pharyngeal raphe def: "The Pharyngeal raphe is a raphe that serves as the origin and insertion for several of the pharyngeal constrictors." [Wikipedia:Pharyngeal_raphe] comment: AO notes: isa anatomical line in FMA synonym: "raphe pharyngis" EXACT [Wikipedia:Pharyngeal_raphe] xref: FMA:55077 ! pharyngeal raphe xref: SCTID:179763009 ! Entire pharyngeal raphe is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0006562 ! pharynx disjoint_from: UBERON:0011346 ! palatine raphe [Term] id: UBERON:0011346 ! palatine raphe name: palatine raphe def: "a raphe running across the palate, from the palatine uvula to the incisive papilla." [Wikipedia:Palatine_raphe] is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0001716 ! secondary palate comment: AO notes: isa anatomical line in FMA synonym: "raphe palati" EXACT [Wikipedia:Palatine_raphe] xref: FMA:75111 ! palatine raphe [Term] id: UBERON:0011347 name: raphe of hard palate intersection_of: UBERON:0011346 ! palatine raphe intersection_of: part_of UBERON:0003216 ! hard palate xref: SCTID:368683007 ! Entire raphe of hard palate def: "A palatine raphe that is part of a hard palate." [OBOL:automatic] [Term] id: UBERON:0011348 name: raphe of soft palate intersection_of: UBERON:0011346 ! palatine raphe intersection_of: part_of UBERON:0001733 ! soft palate xref: SCTID:245785003 ! Entire raphe of soft palate def: "A palatine raphe that is part of a soft palate." [OBOL:automatic] [Term] id: UBERON:0011349 name: pterygomandibular raphe def: "The pterygomandibular raphe (pterygomandibular ligament) is a tendinous band of the buccopharyngeal fascia, attached by one extremity to the hamulus of the medial pterygoid plate, and by the other to the posterior end of the mylohyoid line of the mandible. Its medial surface is covered by the mucous membrane of the mouth. Its lateral surface is separated from the ramus of the mandible by a quantity of adipose tissue. Its posterior border gives attachment to the superior pharyngeal constrictor muscle. Its anterior border attaches to the posterior edge of the buccinator." [Wikipedia:Pterygomandibular_raphe] comment: AO notes: isa anatomical line in FMA synonym: "pterygomandibular ligament" RELATED [Wikipedia:Pterygomandibular_raphe] synonym: "pterygomandibular raph%c3%a9" RELATED [Wikipedia:Pterygomandibular_raphe] xref: FMA:55618 ! pterygomandibular raphe is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0000165 ! mouth xref: SCTID:142713007 ! Entire pterygomandibular raphe [Term] id: UBERON:0011350 name: mylohyoid raphe synonym: "raphe of the mylohyoid" RELATED [] is_a: UBERON:0002384 ! connective tissue [Term] id: UBERON:0006960 name: ovary stroma def: "The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis." [Wikipedia:Stroma_of_ovary_%28animal_tissue%29_of_ovary] synonym: "stroma of the ovary" EXACT [Wikipedia:Stroma_of_ovary] synonym: "ovary stroma" EXACT [MA:0002991] synonym: "interstitial tissue of ovary" EXACT [FMA:18626] synonym: "stroma ovarica" EXACT [FMA:18626] xref: FMA:18626 ! Ovarian stroma xref: MA:0002991 ! ovary stroma xref: EMAPA:28880 ! mesenchymal stroma of ovary xref: ncithesaurus:Stroma_of_the_Ovarian_Cortex ! stroma of the ovarian cortex intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0000992 ! female gonad relationship: has_part CL:0002095 {source="FMA"} ! hilus cell of ovary xref: SCTID:259306002 ! Entire interstitial tissue of ovary synonym: "stroma ovarii" RELATED LATIN [Wikipedia:Stroma_of_ovary] synonym: "ovarian stroma" EXACT [FMA:18626] xref: UMLS:C0737271 xref: CALOHA:TS-1246 ! Ovarian stroma [Term] id: UBERON:0006965 ! vascular cord name: vascular cord def: "The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]." [GO:0072360, ZFA:0005077] xref: ZFA:0005077 ! vascular cord xref: EFO:0003709 ! vascular cord is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0004535 ! cardiovascular system relationship: site_of GO:0048754 ! branching morphogenesis of a tube relationship: has_part CL:0000566 ! angioblastic mesenchymal cell relationship: has_part CL:0000115 ! endothelial cell xref: TAO:0005077 ! vascular cord [Term] id: UBERON:0010894 name: keratinous tooth comment: The hagfish's jawless mouth contains two parallel rows of pointed keratinous teeth synonym: "horny denticle" EXACT [http://tolweb.org/Hyperoartia] is_a: UBERON:0003913 ! tooth-like structure relationship: has_part GO:0045095 ! keratin filament subset: cyclostome_subset [Term] id: UBERON:0012105 ! baleen plate name: baleen plate def: "a keratinous sieve composed of bristles that enables filter feeding in the mouth of mysticete whales." [Wikipedia:baleen] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000165 ! mouth relationship: composed_primarily_of UBERON:0012106 ! baleen plate bristle [Term] id: UBERON:0012106 name: baleen plate bristle def: "A keratinous bristle that enables filter feeding in the mouth of mysticete whales." [Wikipedia:baleen] synonym: "fringe of baleen plate" EXACT [] synonym: "baleen plate fringe" EXACT [] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0012105 ! baleen plate relationship: has_part GO:0045095 ! keratin filament relationship: only_in_taxon NCBITaxon:9721 ! Cetacea [Term] id: UBERON:0013213 name: ossicone def: "Ossicones are horn-like protuberances on the heads of giraffes, male okapis, and their extinct relatives, such as Sivatherium, and the climacoceratids, such as Climacoceras. Only giraffids have true ossicones (as opposed to horns or antlers). The base that a deer's antlers grow from is very similar to ossicones. Ossicones are similar to the horns of antelopes and cattle, save that they are derived from ossified cartilage, and that the ossicones remain covered in skin and fur, rather than horn. Antlers (such as on deer) are derived from bone tissue: when mature, the skin and fur covering of the antlers, termed \"velvet,\" is sloughed and scraped off to expose the bone of the antlers." [Wikipedia:Ossicone] is_a: UBERON:0006969 ! cranial appendage relationship: only_in_taxon NCBITaxon:9892 ! Giraffidae [Term] id: UBERON:0006967 ! horn name: horn def: "a pointed projection of the skin on the head of various animals, consisting of a covering of horn (keratin and other proteins) surrounding a core of living bone." [Wikipedia:Horn_(anatomy)] xref: MESH:A13.507 ! horn xref: GAID:1225 ! horn xref: SCTID:69221006 ! Horn structure is_a: UBERON:0006969 ! cranial appendage relationship: never_in_taxon NCBITaxon:9606 {source="ISBN10:9780716717553"} ! Homo sapiens [Term] id: UBERON:0006968 name: keratin sheath of horn is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0006967 ! horn relationship: has_part GO:0045095 ! keratin filament [Term] id: UBERON:0006969 ! cranial appendage name: cranial appendage is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0006970 name: bony core of horn is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0006967 ! horn [Term] id: UBERON:0006971 name: antler def: "Antlers are the usually large, branching bony appendages on the heads of most deer species." [Wikipedia:Antler] xref: BTO:0001684 ! antler xref: MESH:A13.507.288 xref: GAID:1226 ! antler is_a: UBERON:0006969 ! cranial appendage relationship: only_in_taxon NCBITaxon:9850 ! Cervidae xref: SCTID:410034008 ! Entire antler [Term] id: UBERON:0012458 name: antler velvet def: "highly vascular skin called velvet that covers the antler whilst it grows, supplying oxygen and nutrients to the growing bone." [Wikipedia:Velvet_(antler_covering)] synonym: "velvet of antler" EXACT [SCTID:47282002] xref: SCTID:47282002 ! Velvet of antler is_a: UBERON:0000014 ! zone of skin relationship: part_of UBERON:0006971 ! antler [Term] id: UBERON:0012459 name: antler pedicle def: "attachment point for antler on skull" [Wikipedia:Antler#Occurrence_and_function, Wikipedia:Pedicle_(cervidae)] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0006971 ! antler [Term] id: UBERON:0013073 name: rattle def: "." [Wikipedia:Rattlesnake#Rattle] comment: The rattle is composed of a series of hollow, interlocked segments made of keratin, which are created by modifying the scales that cover the tip of the tail. synonym: "snake rattle" EXACT [] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0007812 ! post-anal tail xref: SCTID:10734004 ! Rattle of snake structure [Term] id: UBERON:0006972 ! nephridium name: nephridium def: "An exceretory tubule that usually opens to the exterior by a nephridiopore. The inner end of the tubule may be blind, ending in flame cells (protonephridium) or may open into the coelom through a ciliated funnel (metanephridium)." [Wikipedia:Nephridium] xref: BTO:0000923 ! nephridium is_a: UBERON:0006555 ! excretory tube [Term] id: UBERON:0006973 name: protonephridium def: "a network of dead-end tubules lacking internal openings found in the Phylums Platyhelminthes, kinorhyncha and Rotifera. The ends are called flame cells (if cilliated) or solenocytes (if flagellated); they function in osmoregulation and ionoregulation. The terminal cells are located at the blind end of the protonephridium. Each cell has one or more cilia and their beating inside the protonephridial tube creates an outward going current and hence a partial pressurization in the blind of the tube. Because of this pressurization drives waste fluids from the inside of the animal, they are pulled through small perforations in the terminal cells and into the protonephridium. The perforations in the terminal cell are large enough for small molecules to pass, but larger proteins are retained within the animal. From the bottom of the protonephridium the solutes are led through the tube, formed by the canal cells, and exits the animal from a small opening formed by the nephridiopore. Selective reabsorption of useful molecules by the canal cells occurs as the solutes pass down the tubule. Protonephridia are generally found in basal organisms such as flatworms. Protonephridia likely first arose as a way to cope with a hypotonic environment by removing excess water from the organism (osmoregulation). Their use as excretory/ionoregulatory structures likely arose secondarily." [Wikipedia:Nephridium#Metanephridia] xref: BILA:0000126 ! protonephridium is_a: UBERON:0006972 ! nephridium [Term] id: UBERON:0006974 name: metanephridium def: "a type of excretory gland or nephridium found in many types of invertebrates such as Annelids, Arthropods and Molluscs. It typically consists of a ciliated funnel opening into the body cavity or coelom connected to a duct which may be variously glandularized, folded or expanded (vesiculate) and which typically opens to the organism's exterior. These ciliated tubules pump water carrying surplus ions, metabolic waste, toxins from food, and useless hormones out of the organism through openings known as nephrostomes. This waste is passed out of the body at the nephridiopore. The primary urine produced by filtration of blood (or a similar functioning fluid) is modified into secondary urine through selective reabsorption by the cells lining the metanephridium. In many earthworms the nephridial ducts open into the digestive tract instead, a condition known as enteronephry." [Wikipedia:Nephridium#Metanephridia] xref: BILA:0000127 ! metanephridium is_a: UBERON:0006972 ! nephridium [Term] id: UBERON:0006976 name: peptonephridium def: "Organs opening into the buccal cavity of pharynx (supposedly modified nephridia) of invertebrates." [BTO:0004280] synonym: "esophageal appendage" RELATED [BTO:0004280] synonym: "oesophageal appendage" RELATED [BTO:0004280] xref: BTO:0004280 ! peptonephridium is_a: UBERON:0000062 ! organ relationship: develops_from UBERON:0006972 ! nephridium relationship: part_of UBERON:0001043 ! esophagus subset: organ_slim [Term] id: UBERON:0006983 name: anatomical point def: "Non-material anatomical entity of zero dimension, which forms a boundary of an anatomical line or surface." [CARO:MAH] subset: upper_level xref: CARO:0000009 xref: BILA:0000009 ! anatomical point xref: EHDAA2:0003009 ! anatomical point xref: AEO:0000009 ! anatomical point xref: FMA:9658 ! Anatomical point is_a: UBERON:0000466 ! immaterial anatomical entity xref: AAO:0010266 ! anatomical point xref: TAO:0001839 ! anatomical point [Term] id: UBERON:0006984 ! anatomical surface name: anatomical surface def: "Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures." [CARO:MAH] subset: upper_level xref: CARO:0000010 xref: BILA:0000010 ! anatomical surface xref: EHDAA2:0003192 ! anatomical surface xref: FMA:24137 ! Anatomical surface xref: ID:0000000 ! anatomical surface is_a: UBERON:0000466 ! immaterial anatomical entity xref: ncithesaurus:Anatomic_Surface ! Anatomic Surface xref: AAO:0010270 ! anatomical surface xref: ZFA:0005594 ! anatomical surface xref: UMLS:C1515977 [Term] id: UBERON:0007029 name: surface synonym: "skin" RELATED [BILA:0000118] xref: BILA:0000118 ! surface xref: EHDAA2:0003154 ! organism surface xref: AEO:0000154 ! organism surface is_a: UBERON:0000475 ! organism subdivision xref: ncithesaurus:Surface ! Surface xref: galen:Surface [Term] id: UBERON:0007094 name: visceral muculature xref: BILA:0000132 ! visceral muculature is_a: UBERON:0000383 ! musculature of body [Term] id: UBERON:0007095 name: somatic musculature xref: BILA:0000133 ! somatic musculature is_a: UBERON:0000383 ! musculature of body [Term] id: UBERON:0007036 name: photosensory system xref: BILA:0000140 ! photosensory system is_a: UBERON:0001032 ! sensory system [Term] id: UBERON:0007037 name: mechanosensory system xref: BILA:0000142 ! mechanosensory system intersection_of: UBERON:0001032 ! sensory system intersection_of: capable_of GO:0050954 ! sensory perception of mechanical stimulu [Term] id: UBERON:0007097 name: chordo neural hinge def: "Portion of tissue that is posterior to the developing notochord during tail bud extension." [ZFA:0001082, http://dev.biologists.org/content/136/10/1591.full] comment: In mouse and chick, the derivative of the NSB (with a minor contribution from the CLE), the `chordo-neural-hinge'(CNH) (Cambray and Wilson, 2007; Catala et al., 1995; Charrier et al., 1999), contains progenitors for the ventral neural tube, somites and notochord (Cambray and Wilson, 2002; McGrew et al., 2008). The CNH is continuous with the most recently formed neural tube and notochord (Fig. 2C-D′). By contrast, the tissue immediately caudal to the CNH exclusively produces somites in mouse and chick (McGrew et al., 2008). xref: XAO:0000108 ! chordoneural hinge xref: ZFA:0001082 ! chordo neural hinge xref: VHOG:0001382 ! chordoneural hinge xref: EFO:0003623 ! chordo neural hinge is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0002533 ! tail bud xref: TAO:0001082 ! chordo neural hinge property_value: external_definition "Portion of tissue is a posterior to the developing notochord during tailbud extension.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001082", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "chordoneural hinge" EXACT [VHOG:0001382] property_value: homology_notes "Although there is mounting evidence showing the comparability of events and formation of different nascent tissue types during gastrulation and tail development, recent work also suggests the presence of an ongoing stem cell population capable of contributing to multiple tissue types in the tail of several different vertebrates, situated in the chordoneural hinge region of the tail bud. It would seem likely that secondary signaling centers regulate the fate to be adopted by such pluripotent progenitors.[well established][VHOG]" xsd:string {external_class="VHOG:0001382", ontology="VHOG", source="DOI:10.1002/dvdy.20017 Liu C\, Knezevic V\, Mackem S\, Ventral tail bud mesenchyme is a signaling for tail paraxial mesoderm induction. Developmental Dynamics (2004)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0007121 name: dermatome segment of skin def: "A dermatome is an area of skin that is mainly supplied by a single spinal nerve. There are eight cervical nerves, twelve thoracic nerves, five lumbar nerves and five sacral nerves. Each of these nerves relays sensation (including pain) from a particular region of skin to the brain[WP]." [Wikipedia:Dermatome_(anatomy)] synonym: "dermatome" RELATED [Wikipedia:Dermatome_(anatomy)] synonym: "dermatomic area" RELATED [Wikipedia:Dermatome_(anatomy)] xref: http://upload.wikimedia.org/wikipedia/commons/thumb/9/97/Dermatomes_and_cutaneous_nerves_-_posterior.png/230px-Dermatomes_and_cutaneous_nerves_-_posterior.png xref: FMA:80301 ! dermatome segment of skin xref: SCTID:244023005 ! Dermatome is_a: UBERON:0000014 ! zone of skin disjoint_from: UBERON:0004016 ! dermatome [Term] id: UBERON:0007128 ! glomeral mesenchyme name: glomeral mesenchyme def: "Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm." [ISBN:0815318960] synonym: "corpuscle" RELATED [XAO:0000110] synonym: "glomerulus" RELATED [XAO:0000110] xref: XAO:0000110 ! glomeral mesenchyme is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0003064 ! intermediate mesoderm [Term] id: UBERON:0007144 name: tail of embryo synonym: "embryo tail" EXACT [FMA:85540] xref: FMA:85540 ! Tail of embryo xref: EMAPA:16748 ! tail of embryo is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0007145 ! dome of diaphragm name: dome of diaphragm synonym: "diaphragm dome" EXACT [FMA:13332] xref: FMA:13332 ! Dome of diaphragm xref: EMAPA:18046 ! dome is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001103 ! diaphragm xref: SCTID:244940004 ! Dome of diaphragm xref: VHOG:0000933 ! diaphragm dome property_value: homology_notes "In mammals, the diaphragm muscle divides the thoracoabdominal cavity into thorax and abdomen. In most mammals, the diaphragm is a flat sheet with muscle fibers radiating outward from a central tendon, and the diaphragm's apposition to the cranial surface of the liver gives it a dome-shape. Muscle fiber contraction reduces the curvature of the dome, thereby expanding the thoracic cavity and aspirating air into the lungs.[well established][VHOG]" xsd:string {external_class="VHOG:0000933", ontology="VHOG", source="DOI:10.1016/j.resp.2006.06.003 Brainerd EL\, Owerkowicz T\, Functional morphology and evolution of aspiration breathing in tetrapods. Respiratory physiology and neurobiology (2006)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0007147 name: lumen of midgut synonym: "midgut lumen" EXACT [FMA:54366] xref: FMA:54366 ! Lumen of midgut xref: EMAPA:18377 ! lumen of midgut intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001045 ! midgut relationship: part_of UBERON:0001045 ! midgut def: "An anatomical cavity that surrounded_by a midgut." [OBOL:automatic] [Term] id: UBERON:0007148 name: lumen of hindgut synonym: "hindgut lumen" EXACT [FMA:54367] xref: FMA:54367 ! Lumen of hindgut xref: EMAPA:18396 ! lumen of hindgut intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001046 ! hindgut relationship: part_of UBERON:0001046 ! hindgut def: "An anatomical cavity that surrounded_by a hindgut." [OBOL:automatic] [Term] id: UBERON:0007149 name: inferior thyroid artery def: "The inferior thyroid artery passes upward, in front of the vertebral artery and Longus colli, then turns medialward behind the carotid sheath and its contents, and also behind the sympathetic trunk, the middle cervical ganglion resting upon the vessel. Reaching the lower border of the thyroid gland it divides into two branches, which supply the postero-inferior parts of the gland, and anastomose with the superior thyroid, and with the corresponding artery of the opposite side. The recurrent nerve passes upward generally behind, but occasionally in front of, the artery. This makes it vulnerable to injury during surgery that involves ligating the inferior thyroid artery, such as excision of the lower pole of the thyroid gland." [Wikipedia:Inferior_thyroid_artery] xref: FMA:10662 ! Inferior thyroid artery xref: EMAPA:18623 ! inferior thyroid artery is_a: UBERON:0004573 ! systemic artery relationship: part_of UBERON:0003847 ! thyroid artery xref: ncithesaurus:Inferior_Thyroid_Artery ! Inferior Thyroid Artery xref: SCTID:303419004 ! Entire inferior thyroid artery synonym: "arteria thyreoidea inferior" RELATED LATIN [Wikipedia:Inferior_thyroid_artery] xref: http://upload.wikimedia.org/wikipedia/commons/2/28/Thyrocervical_trunk.png xref: UMLS:C0226264 [Term] id: UBERON:0007150 name: superior thyroid artery def: "The superior thyroid artery arises from the external carotid artery just below the level of the greater cornu of the hyoid bone and ends in the thyroid gland." [Wikipedia:Superior_thyroid_artery] xref: FMA:49472 ! Superior thyroid artery xref: EMAPA:18624 ! superior thyroid artery is_a: UBERON:0004573 ! systemic artery relationship: part_of UBERON:0003847 ! thyroid artery relationship: branch_of UBERON:0001070 ! external carotid artery xref: ncithesaurus:Superior_Thyroid_Artery ! Superior Thyroid Artery xref: SCTID:244218002 ! Entire superior thyroid artery synonym: "arteria thyreoidea superior" RELATED LATIN [Wikipedia:Superior_thyroid_artery] xref: http://upload.wikimedia.org/wikipedia/commons/5/5a/Plate_16_Zuckerkandl.jpg xref: UMLS:C0226093 [Term] id: UBERON:0007151 name: leaflets of mitral valve def: "Leaf of cardiac valve which has as its parts the anterior, and posterior leaflets that is attached to the chorda tendinea of left ventricle and to the frbrous ring of mitral valve.[FMA]" [FMA:7241, FMA:FMA] synonym: "mitral valve leaflet" EXACT [FMA:7241] synonym: "mitral valvular leaflet" EXACT [FMA:7241] xref: FMA:7241 ! Leaflet of mitral valve xref: EMAPA:18628 ! leaflets of mitral valve intersection_of: UBERON:0011741 ! cardiac valve leaflet intersection_of: part_of UBERON:0002135 ! mitral valve relationship: attaches_to UBERON:0005995 ! mitral valve anulus xref: SCTID:244353007 ! Entire leaflet of mitral valve xref: VHOG:0000822 ! mitral valve leaflets synonym: "leaflet of mitral valve" EXACT [FMA:7241] synonym: "mitral valve leaflets" EXACT [VHOG:0000822] property_value: homology_notes "The mature AV (atrioventricular) valve of the adult zebrafish 2-chambered heart is structurally similar to the mammalian AV valves with stratified ECM (extracellular matrix) and supporting chordae tendineae. Therefore, the major cellular and molecular events of valve development are largely conserved among animals with hearts composed of multiple chambers.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000822", ontology="VHOG", source="DOI:10.1161/CIRCRESAHA.109.201566 Combs MD\, Yutzey KE\, Heart valve development. Circulatory Research (2009)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0007153 name: superior epigastric artery xref: FMA:10646 ! Superior epigastric artery xref: EMAPA:18752 ! superior epigastric artery is_a: UBERON:0004573 ! systemic artery relationship: part_of UBERON:0006349 ! epigastric artery relationship: branch_of UBERON:0002456 ! internal thoracic artery relationship: part_of UBERON:0002456 ! internal thoracic artery xref: SCTID:244287004 ! Entire superior epigastric artery [Term] id: UBERON:0007154 name: inferior epigastric vein xref: FMA:21162 ! Inferior epigastric vein xref: EMAPA:18760 ! inferior epigastric vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0006356 ! epigastric vein xref: ncithesaurus:Deep_Epigastric_Vein ! Inferior Epigastric Vein xref: SCTID:286872000 ! Entire inferior epigastric vein xref: UMLS:C0226762 [Term] id: UBERON:0007155 name: superior epigastric vein xref: FMA:4731 ! Superior epigastric vein xref: EMAPA:18761 ! superior epigastric vein is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0006356 ! epigastric vein relationship: tributary_of UBERON:0001589 {source="FMA/obol"} ! internal thoracic vein xref: SCTID:286596001 ! Entire superior epigastric vein [Term] id: UBERON:0007156 name: inferior thyroid vein synonym: "inferior thyroid venous tree" EXACT [FMA:4728] synonym: "vena thyroidea inferioris" EXACT [FMA:4728] xref: FMA:4728 ! Inferior thyroid vein xref: EMAPA:18763 ! inferior thyroid vein is_a: UBERON:0001638 ! vein xref: SCTID:303423007 ! Entire inferior thyroid vein [Term] id: UBERON:0007157 name: superior thyroid vein xref: FMA:14323 ! Superior thyroid vein xref: EMAPA:18764 ! superior thyroid vein is_a: UBERON:0001638 ! vein xref: SCTID:303421009 ! Entire superior thyroid vein [Term] id: UBERON:0007158 name: lumen of anal canal synonym: "anal canal lumen" EXACT [FMA:17357] xref: FMA:17357 ! Lumen of anal canal xref: EMAPA:18836 ! lumen of anal canal intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0000159 ! anal canal relationship: part_of UBERON:0000159 ! anal canal def: "An anatomical cavity that surrounded_by a anal canal." [OBOL:automatic] [Term] id: UBERON:0007159 name: lumen of colon synonym: "colon lumen" EXACT [FMA:18374] xref: FMA:18374 ! Lumen of colon xref: EMAPA:18945 ! lumen of colon intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon xref: SCTID:362156004 ! Entire colonic lumen def: "An anatomical cavity that surrounded_by a colon." [OBOL:automatic] [Term] id: UBERON:0010161 name: lumen of blood vessel synonym: "blood vessel lumen" EXACT [] xref: SCTID:91747007 ! Lumen of blood vessel intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel def: "An anatomical cavity that surrounded_by a blood vessel." [OBOL:automatic] [Term] id: UBERON:0010160 name: lumen of lymphatic vessel synonym: "lumen of lymphatic duct" EXACT [FMA:59681] synonym: "lymphatic vessel lumen" EXACT [FMA:59681] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0001473 ! lymphatic vessel relationship: part_of UBERON:0001473 ! lymphatic vessel xref: FMA:59681 ! lumen of lymphatic vessel def: "An anatomical cavity that surrounded_by a lymphatic vessel." [OBOL:automatic] [Term] id: UBERON:0007160 name: inferior petrosal sinus synonym: "sinus petrosal inferior" EXACT [FMA:50770] xref: FMA:50770 ! Inferior petrosal sinus xref: EMAPA:19234 ! inferior petrosal is_a: UBERON:0001638 ! vein relationship: part_of UBERON:0005486 ! venous dural sinus xref: SCTID:279263009 ! Entire inferior petrosal sinus [Term] id: UBERON:0007161 name: medial arcuate ligament xref: FMA:58282 ! Medial arcuate ligament xref: EMAPA:19237 ! medial arcuate ligaments is_a: UBERON:0000211 ! ligament [Term] id: UBERON:0007162 name: lateral arcuate ligament xref: FMA:58283 ! Lateral arcuate ligament xref: EMAPA:19238 ! lateral arcuate ligaments is_a: UBERON:0000211 ! ligament [Term] id: UBERON:0007163 name: superior meatus def: "The superior meatus, the smallest of the three meatuses of the nose, occupies the middle third of the lateral wall of the nasal cavity. It lies between the superior nasal conchC& and middle nasal conchC&; the sphenopalatine foramen opens into it behind, and the posterior ethmoidal cells in front. The sphenoidal sinus opens into a recess, the sphenoethmoidal recess, which is placed above and behind the superior concha." [Wikipedia:Superior_nasal_meatus] comment: todo - check FMA synonym: "superior nasal meatus" RELATED [Wikipedia:Superior_nasal_meatus] xref: FMA:57480 ! Superior meatus xref: FMA:53138 ! superior nasal meatus xref: EMAPA:19276 ! superior meatus is_a: UBERON:0002553 ! anatomical cavity synonym: "meatus nasi superior" RELATED LATIN [Wikipedia:Superior_nasal_meatus] xref: http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray196.png xref: SCTID:310213007 ! Entire superior nasal meatus [Term] id: UBERON:0007164 name: distal radio-ulnar joint synonym: "articulation radioulnaris distalis" EXACT [FMA:35290] synonym: "distal radioulnar joint" EXACT [FMA:35290] synonym: "inferior radioulnar joint" EXACT [FMA:35290] synonym: "radio-ulnar joint" BROAD [MA:0000462] xref: MA:0000462 ! distal radio-ulnar joint xref: FMA:35290 ! Distal radio-ulnar joint xref: EMAPA:19316 ! distal is_a: UBERON:0001528 ! radio-ulnar joint xref: SCTID:182170009 ! Entire inferior radioulnar joint [Term] id: UBERON:0007165 name: proximal radio-ulnar joint synonym: "superior radioulnar joint" EXACT [FMA:38860] xref: FMA:38860 ! Proximal radio-ulnar joint xref: EMAPA:19317 ! proximal is_a: UBERON:0001528 ! radio-ulnar joint xref: SCTID:361837005 ! Entire proximal radioulnar joint [Term] id: UBERON:0007166 name: left dome of diaphragm synonym: "left dome of diaphragm viewed radiologically" EXACT [FMA:13334] xref: FMA:13334 ! Left dome of diaphragm xref: EMAPA:25047 ! left dome is_a: UBERON:0007145 ! dome of diaphragm xref: SCTID:244941000 ! Left dome of diaphragm [Term] id: UBERON:0007167 name: right dome of diaphragm synonym: "right dome of diaphragm viewed radiologically" EXACT [FMA:13333] xref: FMA:13333 ! Right dome of diaphragm xref: EMAPA:25048 ! right dome is_a: UBERON:0007145 ! dome of diaphragm xref: SCTID:244942007 ! Right dome of diaphragm [Term] id: UBERON:0008188 ! tendon of biceps brachii name: tendon of biceps brachii synonym: "biceps brachii tendon" EXACT [FMA:38152] xref: FMA:38152 ! tendon of biceps brachii xref: EMAPA:25053 ! tendon xref: SCTID:361886007 ! Entire biceps tendon is_a: UBERON:0000043 {source="FMA"} ! tendon intersection_of: UBERON:0000043 ! tendon intersection_of: attaches_to UBERON:0001507 ! biceps brachii def: "A tendon that attaches_to a biceps brachii." [OBOL:automatic] [Term] id: UBERON:0007168 name: long head of biceps brachii def: "The long head originates on the supraglenoid tubercle just above the shoulder joint from where its tendon passes down along the intertubercular groove of the humerus into the joint capsule of the shoulder joint. [1] When the humerus is in motion, the tendon of the long head is held firmly in place in the intertubercular groove by the greater and lesser tubercles and the overlying transverse humeral ligament. During the motion from external to internal rotation, the tendon is forced medially against the lesser tubercle and superiorly against the transverse ligament." [Wikipedia:Biceps_brachii_muscle#Origin_and_insertion] synonym: "caput longum (musculus biceps brachii)" EXACT [FMA:37683] xref: FMA:37683 ! Long head of biceps brachii xref: EMAPA:25054 ! long head is_a: UBERON:0011906 {source="FMA"} ! muscle head relationship: part_of UBERON:0000043 ! tendon relationship: part_of UBERON:0001507 ! biceps brachii [Term] id: UBERON:0007169 name: short head of biceps brachii def: "Proximally (towards the body), the short head of the biceps attaches to (originates from) the coracoid process at the top of the scapula." [Wikipedia:Biceps_brachii_muscle#Origin_and_insertion] xref: FMA:37682 ! Short head of biceps brachii xref: EMAPA:25055 ! short head is_a: UBERON:0011906 {source="FMA"} ! muscle head relationship: part_of UBERON:0000043 ! tendon relationship: part_of UBERON:0001507 ! biceps brachii [Term] id: UBERON:0008192 name: tendon of triceps brachii synonym: "triceps brachii tendon" EXACT [FMA:38380] synonym: "triceps tendon" EXACT [] xref: FMA:38380 ! tendon of triceps brachii xref: SCTID:245105007 ! Entire triceps tendon is_a: UBERON:0000043 {source="FMA"} ! tendon intersection_of: UBERON:0000043 ! tendon intersection_of: attaches_to UBERON:0001509 ! triceps brachii def: "A tendon that attaches_to a triceps brachii." [OBOL:automatic] [Term] id: UBERON:0007170 name: squamous part of occipital bone def: "The squama of the occipital bone, situated above and behind the foramen magnum, is curved from above downward and from side to side." [Wikipedia:Squama_occipitalis] synonym: "occipital squama" EXACT [Wikipedia:Squama_occipitalis] synonym: "squama occipitalis" EXACT [Wikipedia:Squama_occipitalis] synonym: "occipital squama" EXACT [FMA:52860] synonym: "squama of occipital bone" EXACT [FMA:52860] xref: FMA:52860 ! Squamous part of occipital bone xref: EMAPA:25113 ! squamous part of occipital bone is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001676 ! occipital bone xref: SCTID:139077005 ! Entire squamous part of occipital bone synonym: "squama occipitalis" RELATED LATIN [Wikipedia:Squama_occipitalis] xref: http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray131.png [Term] id: UBERON:0007171 name: border of scapula synonym: "scapular border" EXACT [FMA:23797] xref: FMA:23797 ! Border of scapula xref: EMAPA:25124 ! border is_a: UBERON:0006800 {source="FMA"} ! anatomical line relationship: part_of UBERON:0001124 ! pectoral limb scapula [Term] id: UBERON:0007172 ! angle of scapula name: angle of scapula comment: See: http://purl.obolibrary.org/obo/uberon/tracker/58 synonym: "scapular angle" EXACT [FMA:23800] xref: FMA:23800 ! Angle of scapula xref: EMAPA:25125 ! angle is_a: UBERON:0006800 {source="FMA"} ! anatomical line [Term] id: UBERON:0007173 name: lateral border of scapula synonym: "axillary border of scapula" EXACT [FMA:23239] synonym: "lateral border of scapula" EXACT [FMA:23239] synonym: "margo lateralis (scapula)" EXACT [FMA:23239] synonym: "margo lateralis scapulae" EXACT LATIN [FMA:TA, FMA:23239] xref: FMA:23239 ! Lateral part of scapula xref: EMAPA:25126 ! lateral of border is_a: UBERON:0007171 {source="EMAPA-modified"} ! border of scapula synonym: "lateral part of scapula" RELATED [FMA:23239] [Term] id: UBERON:0007174 name: medial border of scapula synonym: "margo medialis (scapula)" EXACT [FMA:23242] synonym: "medial part of scapula" EXACT [FMA:23242] synonym: "vertebral border of scapula" EXACT [FMA:23242] xref: FMA:23242 ! Medial part of scapula xref: EMAPA:25127 ! medial of border is_a: UBERON:0007171 {source="EMAPA-modified"} ! border of scapula synonym: "margo medialis scapulae" EXACT LATIN [FMA:TA, FMA:23242] xref: SCTID:368187009 ! Entire medial border of scapula [Term] id: UBERON:0007175 name: inferior angle of scapula def: "An angle of the scapula formed by the union of the vertebral and axillary borders; its dorsal surface affords attachment to the Teres major and frequently to a few fibers of the Latissimus dorsi.[WP,unvetted]" [Wikipedia:Inferior_angle_of_scapula] synonym: "angulus inferior (scapula)" EXACT [FMA:13315] synonym: "angulus inferior scapulae" EXACT LATIN [Wikipedia:Inferior_angle_of_scapula] xref: FMA:13315 ! Inferior angle of scapula xref: EMAPA:25128 ! inferior angle is_a: UBERON:0007172 {source="EMAPA-modified"} ! angle of scapula [Term] id: UBERON:0007176 name: superior angle of scapula def: "An angle of the scapula formed by the junction of the superior and vertebral borders. It is thin, smooth, rounded, inclined somewhat lateralward, and gives attachment to a few fibers of the Levator scapulae[WP,unvetted]" [Wikipedia:Superior_angle_of_scapula] synonym: "angulus superior (scapula)" EXACT [FMA:23248] synonym: "angulus superior scapulae" EXACT LATIN [Wikipedia:Superior_angle_of_scapula] synonym: "superior medial angle of scapula" EXACT [Wikipedia:Superior_angle_of_scapula] synonym: "medial angle of scapula" EXACT [Wikipedia:Superior_angle_of_scapula] xref: FMA:23248 ! Superior angle of scapula xref: EMAPA:25129 ! superior angle xref: SCTID:368188004 ! Entire superior medial angle of scapula is_a: UBERON:0007172 {source="EMAPA-modified"} ! angle of scapula [Term] id: UBERON:0011941 name: lateral angle of scapula def: "An angle of the scapula that is broad and bears the glenoid cavity or fossa[WP,unvetted]." [Wikipedia:Lateral_angle_of_scapula] synonym: "angulus lateralis (scapula)" EXACT [FMA:23249] synonym: "angulus lateralis scapulae" EXACT LATIN [Wikipedia:Lateral_angle_of_scapula] synonym: "head of scapula" RELATED [Wikipedia:Lateral_angle_of_scapula] synonym: "glenoid angle of scapula" RELATED [Wikipedia:Lateral_angle_of_scapula] is_a: UBERON:0007172 {source="EMAPA-modified"} ! angle of scapula xref: FMA:23249 ! lateral angle of scapula [Term] id: UBERON:0007177 name: lamina propria of mucosa of colon synonym: "colonic lamina propria" EXACT [FMA:15657] synonym: "lamina propria of colonic mucosa" EXACT [FMA:15657] synonym: "lamina propria of colonic mucous membrane" EXACT [FMA:15657] xref: FMA:15657 ! Lamina propria mucosae of colon xref: EMAPA:27395 ! lamina propria of mucosa of colon intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0000317 ! colonic mucosa xref: SCTID:113284008 ! Colonic lamina propria synonym: "lamina propria mucosae of colon" EXACT [FMA:15657] def: "A lamina propria that is part of a colonic mucosa." [OBOL:automatic] [Term] id: UBERON:0007178 name: muscularis mucosae of colon synonym: "lamina muscularis of colonic mucosa" EXACT [FMA:15656] synonym: "lamina muscularis of colonic mucous membrane" EXACT [FMA:15656] synonym: "muscularis mucosa of colon" EXACT [] xref: FMA:15656 ! Muscularis mucosae of colon xref: EMAPA:27399 ! muscularis mucosa of mucosa of colon intersection_of: UBERON:0006676 ! muscularis mucosa intersection_of: part_of UBERON:0000317 ! colonic mucosa xref: SCTID:885000 ! Lamina muscularis of colonic mucous membrane def: "A muscularis mucosa that is part of a colonic mucosa." [OBOL:automatic] [Term] id: UBERON:0007179 name: basal cell layer of urothelium synonym: "basal cell layer of uroepithelium" EXACT [FMA:84154] xref: FMA:84154 ! Basal cell layer of urothelium xref: EMAPA:28806 ! basal cell layer is_a: UBERON:0000119 ! cell layer relationship: part_of UBERON:0000365 ! urothelium [Term] id: UBERON:0007180 name: atretic follicle of ovary synonym: "atretic follicle" EXACT [FMA:18697] synonym: "folliculus atreticus (Ovarium)" EXACT [FMA:18697] xref: FMA:18697 ! Atretic follicle of ovary xref: EMAPA:29874 ! atretic follicle is_a: UBERON:0001305 ! ovarian follicle xref: SCTID:259073003 ! Entire atretic follicle of ovary [Term] id: UBERON:0007181 name: serosa of infundibulum of uterine tube synonym: "serosa of infundibulum of fallopian tube" EXACT [FMA:18324] synonym: "serosa of infundibulum of oviduct" EXACT [FMA:18324] xref: FMA:18324 ! Serosa of infundibulum of uterine tube xref: EMAPA:29903 ! serosa of infundibulum intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum relationship: part_of UBERON:0003983 ! conus arteriosus def: "A serous membrane that is part of a uterine tube infundibulum." [OBOL:automatic] [Term] id: UBERON:0007182 name: muscle layer of infundibulum of uterine tube synonym: "muscle layer of infundibulum of fallopian tube" EXACT [FMA:18336] synonym: "muscle layer of infundibulum of oviduct" EXACT [FMA:18336] synonym: "muscularis of infundibulum of uterine tube" EXACT [FMA:18336] xref: FMA:18336 ! Muscle layer of infundibulum of uterine tube xref: EMAPA:31264 ! muscle layer of infundibulum intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum relationship: part_of UBERON:0003983 ! conus arteriosus def: "A muscle layer that is part of a uterine tube infundibulum." [OBOL:automatic] [Term] id: UBERON:0007190 ! paracentral gyrus name: paracentral gyrus xref: FMA:77537 ! anterior paracentral gyrus (also: UBERON:0007191 'anterior paracentral gyrus') is_a: UBERON:0000200 ! gyrus [Term] id: UBERON:0007191 name: anterior paracentral gyrus xref: FMA:77537 ! anterior paracentral gyrus (also: UBERON:0007190 'paracentral gyrus') is_a: UBERON:0007190 ! paracentral gyrus [Term] id: UBERON:0007192 name: posterior paracentral gyrus xref: FMA:77538 ! posterior paracentral gyrus is_a: UBERON:0007190 ! paracentral gyrus [Term] id: UBERON:0007195 name: stroma of bone marrow def: "The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis." [Wikipedia:Bone_marrow#Stroma] synonym: "bone marrow stroma" EXACT [FMA:21426] xref: FMA:21426 ! stroma of bone marrow is_a: UBERON:0002384 ! connective tissue relationship: part_of UBERON:0002371 ! bone marrow [Term] id: UBERON:0007269 name: pectoral appendage musculature synonym: "pectoral fin musculature" NARROW SENSU [ZFA:0000563] xref: ZFA:0000563 ! pectoral fin musculature xref: EFO:0003540 ! pectoral fin musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0004710 ! pectoral appendage xref: TAO:0000563 ! pectoral fin musculature def: "A musculature that is part of a pectoral appendage." [OBOL:automatic] [Term] id: UBERON:0007270 name: pelvic appendage musculature synonym: "pelvic fin musculature" NARROW SENSU [ZFA:0000258] xref: ZFA:0000258 ! pelvic fin musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0004709 ! pelvic appendage xref: TAO:0000258 ! pelvic fin musculature property_value: external_definition "Musculature that is part of the pelvic fin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000258", date_retrieved="2012-08-14", source="TAO:curator"} def: "A musculature that is part of a pelvic appendage." [OBOL:automatic] [Term] id: UBERON:0007271 name: limb/fin musculature synonym: "fin musculature" NARROW SENSU [ZFA:0000207] xref: ZFA:0000207 ! fin musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0004708 ! limb/fin xref: TAO:0000207 ! fin musculature def: "A musculature that is part of a limb/fin." [OBOL:automatic] [Term] id: UBERON:0007278 name: presumptive sinus venosus def: "Portion of tissue that is part of the heart tube and will become the sinus venosus." [ZFA:0001722] intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0002063 ! sinus venosus relationship: part_of UBERON:0004141 {source="ZFA"} ! heart tube xref: TAO:0002234 ! presumptive sinus venosus xref: ZFA:0001722 ! presumptive sinus venosus [Term] id: UBERON:0007280 name: presumptive endocardium xref: ZFA:0001724 ! presumptive endocardium intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0002165 ! endocardium xref: TAO:0002233 ! presumptive endocardium property_value: external_definition "Portion of tissue that is part of the heart tube and will become the endocardium.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002233", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A presumptive structure that develops_into a endocardium." [OBOL:automatic] [Term] id: UBERON:0006238 name: future brain comment: Usage notes: this class is restricted to neural-tube derived brains subset: emapa_ehdaa2 subset: vertebrate_core synonym: "presumptive brain" EXACT [ZFA:0000146] synonym: "brain rudiment" EXACT [TAO:0000146] xref: EMAPA:16089 ! future brain of neural ectoderm of ectoderm of embryo xref: EMAPA:16471 ! future brain of central nervous system of nervous system of organ system xref: RETIRED_EHDAA2:0000591 ! future brain xref: EHDAA:300 ! future brain xref: EHDAA:830 ! future brain xref: ZFA:0000146 ! presumptive brain xref: EFO:0003431 ! presumptive brain xref: TAO:0000146 ! presumptive brain is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000922 ! embryo relationship: develops_into UBERON:0000955 ! brain relationship: develops_from UBERON:0001049 ! neural tube [Term] id: UBERON:0006240 name: future forebrain comment: TODO. Add relationships to neural plate (both ZFA and EMAPA time this with the neural plate) subset: emapa_ehdaa2 subset: vertebrate_core xref: EMAPA:16640 ! future forebrain xref: ZFA:0000062 ! presumptive forebrain xref: EHDAA:2643 ! future forebrain xref: EFO:0003423 ! presumptive forebrain synonym: "prosencephalon" RELATED [EHDAA2:0000661] synonym: "presumptive forebrain" EXACT [ZFA:0000062] synonym: "presumptive prosencephalon" EXACT [TAO:0000062] is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0001890 ! forebrain relationship: part_of UBERON:0006238 ! future brain xref: EHDAA2:0000661 ! prosencephalon xref: TAO:0000062 ! presumptive forebrain [Term] id: UBERON:0009616 ! presumptive midbrain name: presumptive midbrain comment: TODO - unify naming conventions synonym: "presumptive mesencephalon" EXACT [ZFA:0000148] synonym: "mesencephalon" RELATED [EHDAA2:0000615] synonym: "early midbrain" RELATED [UBERON:cjm] synonym: "future midbrain" RELATED [UBERON:cjm] intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0001891 ! midbrain relationship: part_of UBERON:0006238 {source="ZFA"} ! future brain relationship: develops_from UBERON:0010286 {source="ZFA"} ! midbrain neural tube relationship: develops_from UBERON:0003080 ! anterior neural tube xref: ZFA:0000148 ! presumptive midbrain xref: TAO:0000148 ! presumptive midbrain xref: EFO:0003432 ! presumptive midbrain xref: EHDAA2:0000615 ! mesencephalon def: "A presumptive structure that develops_into a midbrain." [OBOL:automatic] [Term] id: UBERON:0007277 name: presumptive hindbrain def: "The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, \"rhombencephalosynapsis\" is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure." [Wikipedia:Rhombencephalon] comment: TODO - unify naming conventions synonym: "embryonic rhombencephalon" RELATED [CALOHA:TS-2118] synonym: "rhombencephalon" RELATED [EHDAA2:0001630] synonym: "future hindbrain" RELATED [UBERON:cjm] xref: ZFA:0000569 ! presumptive hindbrain xref: EFO:0003440 ! presumptive hindbrain xref: TAO:0000569 ! presumptive hindbrain xref: EHDAA2:0001630 ! rhombencephalon intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0002028 ! hindbrain relationship: part_of UBERON:0006238 ! future brain property_value: external_definition "The embryonic rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. Rhombomeres Rh7-Rh4 form the myelencephalon that will give the medulla oblongata. Rhombomeres Rh3-Rh1 form the metencephalon that will form the pons and the cerebellum[NPX:PDR]." xsd:string {source="NPX:PDR"} xref: CALOHA:TS-2118 ! Embryonic rhombencephalon [Term] id: UBERON:0007283 name: presumptive shield xref: ZFA:0001121 ! presumptive shield xref: EFO:0003444 ! presumptive shield intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0003062 ! primitive knot xref: TAO:0001121 ! presumptive shield property_value: external_definition "Presumptive structure fated to become the shield. Defined by fate mapping[ZFIN:curator]." xsd:string {source="ZFIN:curator"} [Term] id: UBERON:0007284 name: presumptive neural plate xref: ZFA:0000063 ! presumptive neural plate xref: EFO:0003424 ! presumptive neural plate intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0003075 ! neural plate xref: TAO:0000063 ! presumptive neural plate property_value: external_definition "Region of the gastrula which gives rise to the neural plate.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000063", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A presumptive structure that develops_into a neural plate." [OBOL:automatic] [Term] id: UBERON:0007285 name: presumptive paraxial mesoderm xref: ZFA:0000591 ! presumptive paraxial mesoderm xref: EFO:0003443 ! presumptive paraxial mesoderm intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0003077 ! paraxial mesoderm xref: XAO:0004134 ! presumptive paraxial mesoderm xref: TAO:0000591 ! presumptive paraxial mesoderm def: "A presumptive structure that develops_into a paraxial mesoderm." [OBOL:automatic] [Term] id: UBERON:0007286 name: presumptive floor plate xref: ZFA:0001218 ! presumptive floor plate xref: EFO:0003454 ! presumptive floor plate intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0003079 ! floor plate xref: TAO:0001218 ! presumptive floor plate def: "A presumptive structure that develops_into a floor plate." [OBOL:automatic] [Term] id: UBERON:0007287 name: presumptive bulbus arteriosus xref: ZFA:0001712 ! presumptive bulbus arteriosus intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0004152 ! bulbus arteriosus xref: TAO:0002230 ! presumptive bulbus arteriosus property_value: external_definition "Portion of tissue that is part of the heart tube and will become the bulbus arteriosus.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002230", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A presumptive structure that develops_into a bulbus arteriosus." [OBOL:automatic] [Term] id: UBERON:0007288 name: presumptive forebrain midbrain boundary xref: ZFA:0001368 ! presumptive forebrain midbrain boundary xref: EFO:0003463 ! presumptive forebrain midbrain boundary intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005075 ! forebrain-midbrain boundary xref: TAO:0001368 ! presumptive forebrain midbrain boundary def: "A presumptive structure that develops_into a forebrain-midbrain boundary." [OBOL:automatic] [Term] id: UBERON:0007289 name: presumptive rhombomere 1 xref: ZFA:0001207 ! presumptive rhombomere 1 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005499 ! rhombomere 1 xref: TAO:0001207 ! presumptive rhombomere 1 def: "A presumptive structure that develops_into a rhombomere 1." [OBOL:automatic] [Term] id: UBERON:0007290 name: presumptive rhombomere 3 xref: ZFA:0001213 ! presumptive rhombomere 3 xref: EFO:0003451 ! presumptive rhombomere 3 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005507 ! rhombomere 3 xref: TAO:0001213 ! presumptive rhombomere 3 def: "A presumptive structure that develops_into a rhombomere 3." [OBOL:automatic] [Term] id: UBERON:0007291 name: presumptive rhombomere 4 xref: ZFA:0001212 ! presumptive rhombomere 4 xref: EFO:0003450 ! presumptive rhombomere 4 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005511 ! rhombomere 4 xref: TAO:0001212 ! presumptive rhombomere 4 def: "A presumptive structure that develops_into a rhombomere 4." [OBOL:automatic] [Term] id: UBERON:0007292 name: presumptive rhombomere 5 xref: ZFA:0001211 ! presumptive rhombomere 5 xref: EFO:0003449 ! presumptive rhombomere 5 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005515 ! rhombomere 5 xref: TAO:0001211 ! presumptive rhombomere 5 def: "A presumptive structure that develops_into a rhombomere 5." [OBOL:automatic] [Term] id: UBERON:0007293 name: presumptive rhombomere 6 xref: ZFA:0001210 ! presumptive rhombomere 6 xref: EFO:0003448 ! presumptive rhombomere 6 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005519 ! rhombomere 6 xref: TAO:0001210 ! presumptive rhombomere 6 def: "A presumptive structure that develops_into a rhombomere 6." [OBOL:automatic] [Term] id: UBERON:0007294 name: presumptive rhombomere 7 xref: ZFA:0001209 ! presumptive rhombomere 7 xref: EFO:0003447 ! presumptive rhombomere 7 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005523 ! rhombomere 7 xref: TAO:0001209 ! presumptive rhombomere 7 def: "A presumptive structure that develops_into a rhombomere 7." [OBOL:automatic] [Term] id: UBERON:0007295 name: presumptive rhombomere 8 xref: ZFA:0001214 ! presumptive rhombomere 8 xref: EFO:0003452 ! presumptive rhombomere 8 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005527 ! rhombomere 8 xref: TAO:0001214 ! presumptive rhombomere 8 def: "A presumptive structure that develops_into a rhombomere 8." [OBOL:automatic] [Term] id: UBERON:0007296 name: presumptive rhombomere 2 xref: ZFA:0001208 ! presumptive rhombomere 2 intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005569 ! rhombomere 2 xref: TAO:0001208 ! presumptive rhombomere 2 def: "A presumptive structure that develops_into a rhombomere 2." [OBOL:automatic] [Term] id: UBERON:0007297 name: presumptive pronephric mesoderm synonym: "nephron primordium" EXACT [ZFA:0001070] xref: ZFA:0001070 ! presumptive pronephric mesoderm xref: EFO:0003619 ! presumptive pronephric mesoderm intersection_of: UBERON:0006598 ! presumptive structure intersection_of: develops_into UBERON:0005721 ! pronephric mesoderm xref: TAO:0001070 ! presumptive pronephric mesoderm def: "A presumptive structure that develops_into a pronephric mesoderm." [OBOL:automatic] [Term] id: UBERON:0007298 name: pronephric proximal convoluted tubule xref: ZFA:0001620 ! pronephric proximal convoluted tubule intersection_of: UBERON:0001287 ! proximal convoluted tubule intersection_of: part_of UBERON:0002120 ! pronephros xref: TAO:0002238 ! pronephric proximal convoluted tubule def: "A proximal convoluted tubule that is part of a pronephros." [OBOL:automatic] relationship: part_of UBERON:0005309 {source="reference_0000032"} ! pronephric nephron [Term] id: UBERON:0007299 name: choroid plexus of tectal ventricle synonym: "choroid plexus tectal ventricle" EXACT [ZFA:0001445] xref: ZFA:0001445 ! choroid plexus tectal ventricle intersection_of: UBERON:0001886 ! choroid plexus intersection_of: part_of UBERON:0002289 ! cerebral aqueduct xref: TAO:0001445 ! choroid plexus tectal ventricle def: "A choroid plexus that is part of a cerebral aqueduct." [OBOL:automatic] [Term] id: UBERON:0007300 name: pectoral appendage blood vessel synonym: "pectoral fin blood vessel" NARROW SENSU [ZFA:0005301] xref: ZFA:0005301 ! pectoral fin blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004710 ! pectoral appendage xref: TAO:0005301 ! pectoral fin blood vessel def: "A blood vessel that is part of a pectoral appendage." [OBOL:automatic] [Term] id: UBERON:0007301 name: limb/fin blood vessel synonym: "fin blood vessel" NARROW SENSU [ZFA:0005299] xref: ZFA:0005299 ! fin blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004708 ! limb/fin xref: TAO:0005299 ! fin blood vessel def: "A blood vessel that is part of a limb/fin." [OBOL:automatic] [Term] id: UBERON:0007302 name: pectoral appendage vasculature synonym: "pectoral fin vasculature" NARROW SENSU [ZFA:0005096] xref: ZFA:0005096 ! pectoral fin vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0004710 ! pectoral appendage xref: TAO:0005096 ! pectoral fin vasculature def: "A vasculature that is part of a pectoral appendage." [OBOL:automatic] [Term] id: UBERON:0007303 name: pharyngeal vasculature synonym: "branchial vasculature" EXACT [ZFA:0005003] xref: ZFA:0005003 ! pharyngeal vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001042 ! chordate pharynx xref: TAO:0005003 ! pharyngeal vasculature def: "A vasculature that is part of a chordate pharynx." [OBOL:automatic] [Term] id: UBERON:0007304 name: limb/fin vasculature synonym: "fin vasculature" NARROW SENSU [ZFA:0005095] xref: ZFA:0005095 ! fin vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0004708 ! limb/fin xref: TAO:0005095 ! fin vasculature def: "A vasculature that is part of a limb/fin." [OBOL:automatic] [Term] id: UBERON:0012239 name: urinary bladder vasculature def: "network of tubes that carries blood through the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys[MP]" [MP:MP] intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001255 {source="EMAPA"} ! urinary bladder synonym: "blood vessels of bladder" EXACT [EMAPA:28679] synonym: "bladder vasculature" EXACT [] synonym: "set of urinary bladder blood vessels" EXACT [] xref: EMAPA:28679 ! blood vessels of bladder [Term] id: UBERON:0007306 name: pronephric glomerular capillary xref: ZFA:0005309 ! pronephric glomerular capillary intersection_of: UBERON:0004212 ! glomerular capillary intersection_of: part_of UBERON:0002120 ! pronephros xref: TAO:0005309 ! pronephric glomerular capillary def: "A glomerular capillary that is part of a pronephros." [OBOL:automatic] relationship: part_of UBERON:0004739 {is_inferred="true", source="reference_0000032"} ! pronephric glomerulus relationship: part_of UBERON:0005309 {source="reference_0000032"} ! pronephric nephron [Term] id: UBERON:0007307 name: pronephric glomerular basement membrane xref: ZFA:0005313 ! pronephric glomerular basement membrane intersection_of: UBERON:0005777 ! glomerular basement membrane intersection_of: part_of UBERON:0002120 ! pronephros xref: TAO:0005313 ! pronephric glomerular basement membrane def: "A glomerular basement membrane that is part of a pronephros." [OBOL:automatic] relationship: part_of UBERON:0004739 {is_inferred="true", source="reference_0000032"} ! pronephric glomerulus [Term] id: UBERON:0007308 name: pronephric distal early tubule xref: ZFA:0001622 ! pronephric distal early tubule intersection_of: UBERON:0006337 ! distal early tubule intersection_of: part_of UBERON:0002120 ! pronephros xref: TAO:0002236 ! pronephric distal early tubule def: "A distal early tubule that is part of a pronephros." [OBOL:automatic] relationship: part_of UBERON:0005309 {source="reference_0000032"} ! pronephric nephron [Term] id: UBERON:0007384 name: limb/fin lymph vessel xref: ZFA:0005300 ! fin lymph vessel intersection_of: UBERON:0001473 ! lymphatic vessel intersection_of: part_of UBERON:0004708 ! limb/fin relationship: part_of UBERON:0007304 ! limb/fin vasculature xref: TAO:0005300 ! fin lymph vessel def: "A lymphatic vessel that is part of a limb/fin." [OBOL:automatic] [Term] id: UBERON:0007385 name: pectoral appendage lymph vessel xref: TAO:0005302 ! pectoral fin lymph vessel xref: ZFA:0005302 ! pectoral fin lymph vessel intersection_of: UBERON:0001473 ! lymphatic vessel intersection_of: part_of UBERON:0004710 ! pectoral appendage relationship: part_of UBERON:0007302 ! pectoral appendage vasculature def: "A lymphatic vessel that is part of a pectoral appendage." [OBOL:automatic] [Term] id: UBERON:0007386 name: pelvic appendage lymph vessel intersection_of: UBERON:0001473 ! lymphatic vessel intersection_of: part_of UBERON:0004709 ! pelvic appendage def: "A lymphatic vessel that is part of a pelvic appendage." [OBOL:automatic] [Term] id: UBERON:0007389 name: limb/fin cartilage xref: TAO:0001543 ! paired fin cartilage xref: ZFA:0001543 ! paired fin cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0004708 ! limb/fin relationship: part_of UBERON:0002091 ! appendicular skeleton property_value: external_definition "Cartilage which is part of one of the paired fins.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0001543", date_retrieved="2012-08-14", source="ZFIN:curator"} def: "A cartilage tissue that is part of a limb/fin." [OBOL:automatic] [Term] id: UBERON:0007475 name: matrix-based tissue alt_id: EHDAA2:0003081 def: "A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified." [AEO:JB] xref: AEO:0000081 ! matrix-based tissue intersection_of: UBERON:0000479 ! tissue intersection_of: composed_primarily_of GO:0031012 ! extracellular matrix xref: EHDAA2:0003081 ! matrix-based tissue [Term] id: UBERON:0007486 name: fluid-based anatomical entity alt_id: EHDAA2:0003095 def: "Fluid anatomical entity containing cells." [AEO:JB] xref: AEO:0000095 ! fluid-based anatomical entity is_a: UBERON:0000481 {source="AEO"} ! multi-tissue structure xref: EHDAA2:0003095 ! fluid-based anatomical entity [Term] id: UBERON:0007490 name: keratin-based acellular structure alt_id: EHDAA2:0003099 def: "Acellular anatomical structure whose predominant constituent is keratin." [AEO:JB] xref: AEO:0000099 ! keratin-based acellular structure intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: composed_primarily_of GO:0045095 ! keratin filament xref: EHDAA2:0003099 ! keratin-based structure [Term] id: UBERON:0007491 name: chitin-based acellular structure alt_id: EHDAA2:0003100 def: "Acellular anatomical structure whose predominant constituent is chitin." [AEO:JB] xref: AEO:0000100 ! chitin-based acellular structure intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: composed_primarily_of CHEBI:17029 ! chitin xref: EHDAA2:0003100 ! chitin-based structure [Term] id: UBERON:0005153 ! epithelial bud name: epithelial bud def: "A bud is a protrusion that forms from an epithelial sheet by localized folding." [GO:0060572] is_a: UBERON:0005157 ! epithelial fold xref: BTO:0001639 ! bud [Term] id: UBERON:0007499 ! epithelial sac name: epithelial sac def: "An epithelial tube that is open at one end only." [AEO:JB, UBERONREF:0000001] xref: AEO:0000115 ! epithelial sac xref: EHDAA2:0003115 ! epithelial sac is_a: UBERON:0003914 {source="AEO"} ! epithelial tube intersection_of: UBERON:0000483 ! epithelium intersection_of: has_quality PATO:0001987 ! saccular [Term] id: UBERON:0009856 ! sac name: sac synonym: "pouch" EXACT [] synonym: "diverticulum" RELATED [] intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001987 ! saccular xref: galen:Diverticulum ! diverticulum [Term] id: UBERON:0007500 name: epithelial tube open at both ends xref: RETIRED_EHDAA2:0003116 def: "An epithelial tube open at both ends that allows fluid flow." [AEO:JB, UBERONREF:0000001] xref: AEO:0000116 ! epithelial tube open at both ends xref: RETIRED_EHDAA2:0003116 ! epithelial tube open at both ends is_a: UBERON:0003914 {source="AEO"} ! epithelial tube [Term] id: UBERON:0007501 name: arborizing epithelial duct system alt_id: EHDAA2:0003117 def: "A collection of connected epithelial tubes with a single portal." [AEO:JB, UBERONREF:0000001] synonym: "arborising epithelial duct system" EXACT [AEO:0000117] xref: AEO:0000117 ! arborising epithelial duct system is_a: UBERON:0007499 {source="AEO"} ! epithelial sac relationship: has_part UBERON:0003914 {source="AEO"} ! epithelial tube xref: EHDAA2:0003117 ! arborising epithelial duct system [Term] id: UBERON:0007502 name: epithelial plexus alt_id: EHDAA2:0003118 def: "A complex of interlinking epithelial tubules." [AEO:JB] xref: AEO:0000118 ! epithelial plexus is_a: UBERON:0003914 {source="AEO"} ! epithelial tube relationship: has_part UBERON:0003914 {source="AEO"} ! epithelial tube xref: EHDAA2:0003118 ! epithelial plexus [Term] id: UBERON:0007503 ! epithelial vesicle name: epithelial vesicle alt_id: EHDAA2:0003119 def: "A closed epithelium with a lumen." [AEO:JB] xref: AEO:0000119 ! epithelial vesicle is_a: UBERON:0000483 {source="AEO"} ! epithelium xref: EHDAA2:0003119 ! epithelial vesicle [Term] id: UBERON:0007473 name: lumen of epithelial sac alt_id: EHDAA2:0003079 def: "The space within an epithelial sphere." [AEO:JB] synonym: "cavity of vesicle" EXACT [AEO:0000079] xref: AEO:0000079 ! cavity of vesicle intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0007499 ! epithelial sac relationship: has_quality PATO:0000608 ! closed [Term] id: UBERON:0013525 name: stomach lumen synonym: "gastric cavity" RELATED [FMA:14585] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0000945 ! stomach relationship: part_of UBERON:0011565 {source="FMA"} ! lumen of gastrointestinal system synonym: "cavity of stomach" EXACT [FMA:14585] xref: FMA:14585 ! cavity of stomach [Term] id: UBERON:0007524 name: dense mesenchyme tissue alt_id: EHDAA2:0003146 def: "Mesenchyme with little extracellular matrix." [AEO:JB] xref: AEO:0000146 ! dense mesenchyme tissue xref: EHDAA2:0003146 ! dense mesenchymal tissue is_a: UBERON:0003104 {source="AEO"} ! mesenchyme relationship: has_part CL:0000057 {source="AEO"} ! fibroblast [Term] id: UBERON:0007529 name: loose mesenchyme tissue alt_id: EHDAA2:0003151 def: "Mesenchyme whose cells are embedded in obvious amounts of extracellular matrix." [AEO:JB] xref: AEO:0000151 ! loose mesenchyme tissue xref: EHDAA2:0003151 ! loose mesenchymal tissue is_a: UBERON:0003104 {source="AEO"} ! mesenchyme relationship: has_part CL:0000057 {source="AEO"} ! fibroblast relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell !disjoint_from: UBERON:0007524 ! dense mesenchyme tissue UNSAT: EHDAA2:0004581 'future jejunum & ileum mesentery (embryonic human)' UNSAT: EHDAA2:0004580 'coecum mesentery (embryonic human)' UNSAT: EHDAA2:0004579 'midgut part of future large intestine mesentery (embryonic human)' UNSAT: EHDAA2:0004718 'chorionic villus mesenchyme (embryonic human)' [Term] id: UBERON:0007530 name: migrating mesenchyme population alt_id: EHDAA2:0003152 def: "Mesenchymal cells that are migrating." [AEO:JB] comment: Editors note: this class will be an important part of the NC reorganization xref: AEO:0000152 ! migrating mesenchyme population intersection_of: UBERON:0003104 ! mesenchyme intersection_of: participates_in GO:0016477 ! cell migration xref: EHDAA2:0003152 ! migrating mesenchyme population [Term] id: UBERON:0007540 name: obsolete surface sense organ consider: AEO:0000173 ! surface sense organ consider: EHDAA2:0003173 ! surface sense organ is_obsolete: true comment: obsoleted due to incorrect logical definition. A new class with the same name may be created in the future. [Term] id: UBERON:0012437 ! epithelial-mesenchymal boundary name: epithelial-mesenchymal boundary intersection_of: UBERON:0006800 ! anatomical line intersection_of: adjacent_to UBERON:0000483 ! epithelium intersection_of: adjacent_to UBERON:0003104 ! mesenchyme [Term] id: UBERON:0007567 name: regenerating anatomical structure alt_id: EHDAA2:0003233 def: "An anatomical structure that, as part of its normal physiology, undergoes regeneration. Examples include endometrium and antlers." [AEO:JB] comment: Editor notes: we define this in terms of active participation in regeneration, rather that capabilities. In this sense it is different from the AEO structure. xref: AEO:0000200 ! regenerating anatomical structure xref: ZFA:0005147 ! regenerating tissue synonym: "regenerating tissue" RELATED [ZFA:0005147] synonym: "regenerative tissue" RELATED [] intersection_of: UBERON:0000061 ! anatomical structure intersection_of: participates_in GO:0031099 ! regeneration relationship: capable_of GO:0031099 ! regeneration xref: EHDAA2:0003233 ! regenerating anatomical structure xref: XAO:0004059 ! regenerating tissue xref: TAO:0005147 ! regenerating tissue property_value: external_definition "A portion of tissue that is regrowing after damage or amputation.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005147", date_retrieved="2012-08-14", source="ZFIN:curator"} [Term] id: UBERON:2001269 name: regenerating fin/limb def: "Fin or limb undergoing the process of regeneration." [UBERON:cjm] synonym: "regenerating fins" NARROW PLURAL [ZFA:0001269] intersection_of: UBERON:0004708 ! limb/fin intersection_of: participates_in GO:0031099 ! regeneration xref: EFO:0003657 ! regenerating fin xref: TAO:0001269 ! regenerating fin xref: ZFA:0001269 ! regenerating fin [Term] id: UBERON:2001389 name: regeneration epithelium of fin/limb synonym: "epidermal cap" BROAD [ZFA:0001389] synonym: "wound epidermis" BROAD [ZFA:0001389] synonym: "wound epithelium" BROAD [ZFA:0001389] synonym: "epidermal cap of fin" EXACT [] synonym: "wound epidermis of fin" EXACT [] synonym: "wound epithelium of fin" EXACT [] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:2001269 ! regenerating fin/limb xref: ZFA:0001389 ! regeneration epithelium xref: TAO:0001389 ! regeneration epithelium xref: EFO:0003682 ! regeneration epithelium [Term] id: UBERON:2001388 name: epithelial mesenchymal boundary of regenerating fin/limb intersection_of: UBERON:0012437 ! epithelial-mesenchymal boundary intersection_of: part_of UBERON:2001269 ! regenerating fin/limb xref: ZFA:0001388 ! epithelial mesenchymal boundary xref: TAO:0001388 [Term] id: UBERON:2005149 name: distal epidermal cap of regenerating fin/limb def: "Part of regeneration epithelium at the tip of the fin/limb [ZFA,modified]." [ZFIN:curator] is_a: UBERON:0007567 ! regenerating anatomical structure relationship: part_of UBERON:2001389 ! regeneration epithelium of fin/limb xref: ZFA:0005149 ! distal epidermal cap xref: TAO:0005149 ! distal epidermal cap [Term] id: UBERON:2005150 name: basal regeneration epithelium of regenerating fin/limb def: "Layer of the wound epidermis that surrounds the blastema in the fin or limb[ZFA,modified]." [ZFIN:curator] synonym: "basal wound epidermis" EXACT [UBERON:2005150] is_a: UBERON:0007567 ! regenerating anatomical structure relationship: part_of UBERON:2001389 ! regeneration epithelium of fin/limb xref: ZFA:0005150 ! basal regeneration epithelium xref: TAO:0005150 ! basal regeneration epithelium [Term] id: UBERON:0005306 name: blastema def: "A blastema is a mass of cells capable of growth and regeneration into organs or body parts. Historically blastema have been thought to be composed of undifferentiated pluripotent cells, but recent research indicates that in some organisms blastema may retain memory of tissue origin.[1] Blastemata are typically found in the early stages of an organism's development such as in embryos, and in the regeneration of tissues, organs and bone[WP]. A regenerating tissue composed of a proliferative mass of undifferentiated progenitor cells from which new differentiated structures arise[ZFA]." [ZFIN:ZDB-PUB-061108-12, ZFA:0001270, Wikipedia:Blastema] comment: Note the ZFA class called 'blastema' belongs with the subclass, blastema of regenerating fin/limb synonym: "regeneration blastema" EXACT [ZFIN:ZDB-PUB-061108-12] synonym: "blastemata" EXACT PLURAL [] xref: TAO:0001270 ! blastema xref: BTO:0001638 ! blastema xref: EFO:0003658 ! blastema is_a: UBERON:0007567 {source="ZFA"} ! regenerating anatomical structure relationship: has_part CL:0000354 ! blastemal cell relationship: capable_of GO:0040007 ! growth xref: XAO:0004060 ! blastema [Term] id: UBERON:0012438 name: blastema of regenerating fin/limb intersection_of: UBERON:0005306 ! blastema intersection_of: part_of UBERON:2001269 ! regenerating fin/limb xref: ZFA:0001270 ! blastema [Term] id: UBERON:0012439 name: blastema of regenerating digit tip synonym: "digit blastema" RELATED [] intersection_of: UBERON:0005306 ! blastema intersection_of: part_of UBERON:0009551 ! distal segment of digit [Term] id: UBERON:0007573 name: migrating epithelium alt_id: EHDAA2:0003251 def: "An epithelium that extends its surface area by peripheral movement." [AEO:JB] xref: AEO:0000206 ! migrating epithelium is_a: UBERON:0000483 {source="AEO"} ! epithelium xref: EHDAA2:0003251 ! migrating epithelium [Term] id: UBERON:0007574 name: apical epidermal cap synonym: "apical epidermal caps" EXACT PLURAL [ZFA:0005148] synonym: "apical epithelial cap" EXACT [Wikipedia:Blastema] xref: TAO:0005148 ! apical epidermal cap xref: ZFA:0005148 ! apical epidermal cap is_a: UBERON:0007567 {source="ZFA"} ! regenerating anatomical structure relationship: part_of UBERON:2001389 {source="ZFA"} ! regeneration epithelium of fin property_value: external_definition "Part of the regeneration epithelium closest to the fin.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005148", date_retrieved="2012-08-14", source="ZFIN:curator"} relationship: present_in_taxon NCBITaxon:8293 {source="Wikipedia"} ! Caudata [Term] id: UBERON:0007626 name: subparaventricular zone xref: ABA:SBPV ! Subparaventricular zone xref: MA:0000842 ! subparaventricular zone is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002272 {source="MA"} ! medial zone of hypothalamus relationship: spatially_disjoint_from UBERON:0002690 {source="ABA"} ! anteroventral periventricular nucleus relationship: spatially_disjoint_from UBERON:0001934 {source="ABA"} ! dorsomedial nucleus of hypothalamus relationship: spatially_disjoint_from UBERON:0002625 {source="ABA"} ! median preoptic nucleus relationship: spatially_disjoint_from UBERON:0002689 {source="ABA"} ! supraoptic crest relationship: spatially_disjoint_from UBERON:0002034 {source="ABA"} ! suprachiasmatic nucleus relationship: spatially_disjoint_from UBERON:0002219 {source="ABA"} ! subfornical organ [Term] id: UBERON:0006122 name: obsolete retrorubral area is_obsolete: true comment: Made obsolete as it grouped two unrelated classes synonym: "A8" RELATED [NIF_GrossAnatomy:nlx_anat_20090301] consider: FMA:66581 ! trunk of anterior basal segmental artery consider: NIF_GrossAnatomy:nlx_anat_20090301 ! Retrorubral area [Term] id: UBERON:0011172 name: retrorubral area def: "The term retrorubral area refers to a region of the rat brain caudal to the red nucleus and caudal and dorsal to the ventral tegmental area identified by Nissl stain in the rat ( Swanson-2004 ) and the mouse ( Hof-2000; Paxinos-2001 ). It is one of three parts of the midbrain reticular nucleus; the other two are the magnocellular part of the midbrain reticular nucleus and the parvicellular part of the midbrain reticular nucleus ( Swanson-2004 ). Some authors restrict its definition to the part of the retrorubral area where dopaminergic cells of the A8 cell group are prominent" [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=1049] synonym: "A8" BROAD [NIF_GrossAnatomy:nlx_anat_20090301] synonym: "retrorubal field" BROAD [http://braininfo.rprc.washington.edu/] synonym: "midbrain reticular nucleus, retrorubral area" EXACT [ABA:RR] is_a: UBERON:0002950 {source="NIF_GrossAnatomy"} ! regional part of midbrain relationship: part_of UBERON:0007415 {source="Obol"} ! nucleus of midbrain reticular formation xref: NIF_GrossAnatomy:nlx_anat_20090301 ! Retrorubral area xref: ABA:RR ! Midbrain reticular nucleus, retrorubral area [Term] id: UBERON:0007628 ! lateral septal complex name: lateral septal complex comment: todo - split nucleus and complex xref: ABA:LSX ! Lateral septal complex xref: MA:0000933 ! lateral septal complex xref: FMA:61878 ! Lateral septal nucleus (also: UBERON:0002667 'lateral septal nucleus') is_a: UBERON:0002663 {source="MA"} ! septal nuclear complex relationship: part_of UBERON:0002435 {source="ABA"} ! striatum [Term] id: UBERON:0007629 name: medial septal complex xref: ABA:MSC ! Medial septal complex xref: MA:0000934 ! medial septal complex xref: FMA:61879 ! Medial septal nucleus (also: UBERON:0001877 'medial septal nucleus') xref: FMA:61879 ! medial septal nucleus (also: UBERON:0001877 'medial septal nucleus') is_a: UBERON:0002663 {source="MA"} ! septal nuclear complex relationship: spatially_disjoint_from UBERON:0002977 {source="ABA"} ! triangular septal nucleus [Term] id: UBERON:0007630 name: septohippocampal nucleus xref: ABA:SH ! Septohippocampal nucleus xref: MA:0000939 ! septohippocampal nucleus is_a: UBERON:0002663 {source="MA"} ! septal nuclear complex relationship: part_of UBERON:0007628 ! lateral septal complex relationship: spatially_disjoint_from UBERON:0002667 {source="ABA"} ! lateral septal nucleus relationship: spatially_disjoint_from UBERON:0001878 {source="ABA"} ! septofimbrial nucleus [Term] id: UBERON:0007631 name: accessory olfactory bulb glomerular layer xref: ABA:AOBgl ! Accessory olfactory bulb, glomerular layer xref: MA:0000967 ! accessory olfactory bulb glomerular layer is_a: UBERON:0005162 ! multi cell component structure relationship: part_of UBERON:0004069 {source="ABA"} ! accessory olfactory bulb [Term] id: UBERON:0007632 name: Barrington's nucleus xref: ABA:B ! Barrington's nucleus xref: MA:0001011 ! barrington's nucleus is_a: UBERON:0006331 {source="MA"} ! brainstem nucleus relationship: part_of UBERON:0000988 {source="MA"} ! pons relationship: spatially_disjoint_from UBERON:0002143 {source="ABA"} ! dorsal tegmental nucleus relationship: spatially_disjoint_from UBERON:0002968 {source="ABA"} ! central gray substance of pons relationship: spatially_disjoint_from UBERON:0002151 {source="ABA"} ! pontine nuclear group relationship: spatially_disjoint_from UBERON:0002963 {source="ABA"} ! caudal pontine reticular nucleus relationship: spatially_disjoint_from UBERON:0002149 {source="ABA"} ! superior salivatory nucleus relationship: spatially_disjoint_from UBERON:0002147 {source="ABA"} ! reticulotegmental nucleus relationship: spatially_disjoint_from UBERON:0002633 {source="ABA"} ! motor nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002682 {source="ABA"} ! abducens nucleus relationship: spatially_disjoint_from UBERON:0003011 {source="ABA"} ! facial motor nucleus [Term] id: UBERON:0007634 name: parabrachial nucleus xref: ABA:PB ! Parabrachial nucleus xref: MA:0001019 ! parabrachial nucleus xref: BM:PB ! parabrachial nucleus is_a: UBERON:0006331 {source="MA"} ! brainstem nucleus relationship: part_of UBERON:0000988 {source="MA"} ! pons relationship: spatially_disjoint_from UBERON:0006840 {source="ABA"} ! nucleus of lateral lemniscus relationship: spatially_disjoint_from UBERON:0002597 {source="ABA"} ! principal sensory nucleus of trigeminal nerve relationship: spatially_disjoint_from UBERON:0002128 {source="ABA"} ! superior olivary complex [Term] id: UBERON:0007770 name: osphradium def: "The osphradium is the olfactory organ in certain molluscs, linked with the respiration organ. The main function of this is to test incoming water for silt and other possible food particles. It is used by all members of the Genus Conus." [Wikipedia:Osphradium, BTO:0004995] xref: BTO:0004995 ! osphradium is_a: UBERON:0002268 {source="BTO"} ! olfactory organ relationship: only_in_taxon NCBITaxon:6447 ! Mollusca subset: organ_slim [Term] id: UBERON:0007805 name: synsacrum def: "The synsacrum is a skeletal structure, mainly described in birds and dinosaurs, in which the sacrum is extended by incorporation of additional fused or partially-fused caudal or lumbar vertebrae. The ilium of the pelvis is attached to the synsacrum and, in some species, may also be fused to it. Together with the pelvis this forms a rigid structure which carries the weight of the hind end of the animal. In living and some prehistoric birds, posterior to the synsacrum there are usually only a few free caudal vertebrae, on the end of which lies the pygostyle[WP]. Complex of synostotically fused vertebrae supporting the pelvic girdle. In anurans, the synsacrum is formed by two vertebrae and the urostyle is fused to its posterior end[AAO]." [AAO:Pugener_2002, Wikipedia:Synsacrum] comment: produced by fusion of last thoracics, all lumbars, all sacrals, & first few caudals; xref: AAO:0000740 ! synsacrum is_a: UBERON:0001474 ! bone element relationship: part_of UBERON:0006075 {source="AAO"} ! sacral region of vertebral column xref: SCTID:67943001 ! Synsacrum xref: http://people.eku.edu/ritchisong/birdskeleton.gif property_value: external_definition "Complex of synostotically fused vertebrae supporting the pelvic girdle. In anurans, the synsacrum is formed by two vertebrae and the urostyle is fused to its posterior end.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000740", date_retrieved="2012-06-20", source="AAO:Pugener_2002"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass portion of (AAO:0010428)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0000740", date_retrieved="2012-06-20"} [Term] id: UBERON:0007914 name: head or neck bone xref: MA:0000569 ! head or neck bone is_a: UBERON:0001474 {source="MA"} ! bone element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0007811 {source="MA"} ! craniocervical region def: "A bone that is part of a craniocervical region." [OBOL:automatic] [Term] id: UBERON:0012131 name: centrale def: "Endochondral bone located between the proximal and distal rows of carpals or tarsals and thus representing the central carpals or tarsals[PHENOSCAPE]." [PHENOSCAPE:AMAO] synonym: "os centrale" EXACT [FMA:77232] synonym: "central mesopodium bone" EXACT [] comment: Usage notes: This term corresponds both to the navicular bone in the pes and the similar central carpals in the manus. AO notes: the FMA term is under 'general anatomical term'. xref: FMA:77232 ! os centrale is_a: UBERON:0002513 {source="phenoscape"} ! endochondral bone relationship: part_of UBERON:0009878 ! mesopodial skeleton [Term] id: UBERON:0007958 name: central carpal bone def: "A small bone occasionally found at the dorsal aspect of the wrist between the scaphoid, capitate, and trapezoid; it is developed as an independent cartilage in early foetal life but usually becomes fused with the scaphoid; it occurs normally in most monkeys." [http://www.medilexicon.com/medicaldictionary.php?t=63518] synonym: "central carpals" EXACT [] synonym: "os centrale" BROAD [] synonym: "centrale" BROAD [MA:0001344] synonym: "os carpi centrale" RELATED [http://epub.ub.uni-muenchen.de/8251/1/8251.pdf] synonym: "os centrale carpi" RELATED [] synonym: "central bone" BROAD [http://www.medilexicon.com/medicaldictionary.php?t=63518] xref: MA:0001344 ! central carpal bone is_a: UBERON:0012131 ! centrale is_a: UBERON:0001435 {source="MA"} ! carpal bone xref: SCTID:26987000 ! Central carpal bone [Term] id: UBERON:0007959 name: falciform carpal bone comment: todo - check relationship to radial sesamoid synonym: "os falciform" EXACT [UBERON:cjm] synonym: "os falciforme" EXACT [UBERON:cjm] xref: MA:0001345 ! falciform carpal bone is_a: UBERON:0001435 {source="MA"} ! carpal bone [Term] id: UBERON:0008257 name: radial sesamoid def: "In the giant panda, a large digitlike preaxial element that articulates with the scapholunatum and the medial border of the first metacarpal." [ISBN-10:0226313379] synonym: "os sesamoideum radiale" EXACT [ISBN-10:0226313379] is_a: UBERON:0001479 ! sesamoid bone relationship: part_of UBERON:0009880 ! carpal skeleton relationship: preaxial_part_of UBERON:0009880 ! carpal skeleton relationship: connected_to UBERON:0007960 ! scapholunate relationship: connected_to UBERON:0003645 ! metacarpal bone of digit 1 [Term] id: UBERON:0007960 name: scapholunate def: "The combined scaphoid and lunate bones." [UBERON:cjm] comment: Taxon notes: present in mouse[based on MA], carnivora[Websters] and macropods[WP]. synonym: "intermedioradial carpal bone" RELATED [MA:0001346] synonym: "scapholunatum" RELATED [UBERON:cjm] synonym: "scapholunate bone" EXACT [UBERON:cjm] xref: MA:0001346 ! scapholunate is_a: UBERON:0001480 {source="MA"} ! proximal carpal bone relationship: has_fused_element UBERON:0001427 ! scaphoid relationship: has_fused_element UBERON:0001428 ! lunate [Term] id: UBERON:0008254 name: styliform cartilage def: "shaft of skeletal tissue that articulates with the lateral border of the carpus." [ISBN-10:0226313379] is_a: UBERON:0007844 ! cartilage element relationship: part_of UBERON:0001440 ! forelimb skeleton relationship: has_function_in GO:0060361 ! flight relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: homologous_to UBERON:0001429 {comment="checkme"} ! pisiform [Term] id: UBERON:0007990 name: proximal sesamoid bone of pes xref: MA:0001376 ! proximal sesamoid bone of foot is_a: UBERON:0004248 {source="MA"} ! pedal digit bone is_a: UBERON:0001479 {source="MA"} ! sesamoid bone synonym: "proximal sesamoid bone of foot" EXACT [MA:0001376] [Term] id: UBERON:0007991 name: proximal sesamoid bone of manus xref: MA:0001377 ! proximal sesamoid bone of hand synonym: "proximal sesamoid bone of hand" EXACT [MA:0001377] is_a: UBERON:0004249 {source="MA"} ! manual digit bone is_a: UBERON:0001479 {source="MA"} ! sesamoid bone [Term] id: UBERON:0007997 name: sesamoid bone of manus xref: FMA:42353 ! sesamoid bone of hand is_a: UBERON:0001479 {source="FMA"} ! sesamoid bone intersection_of: UBERON:0001479 ! sesamoid bone intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0001442 ! skeleton of manus xref: SCTID:368448000 ! Entire sesamoid bone of hand synonym: "sesamoid bone of hand" EXACT [FMA:42353] def: "A sesamoid bone that is part of a manus." [OBOL:automatic] [Term] id: UBERON:0008000 name: sesamoid bone of pes xref: FMA:45096 ! sesamoid bone of foot is_a: UBERON:0001479 {source="FMA"} ! sesamoid bone intersection_of: UBERON:0001479 ! sesamoid bone intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0001445 {source="FMA"} ! skeleton of pes xref: SCTID:244675002 ! Entire sesamoid bone of foot synonym: "sesamoid bone of foot" EXACT [FMA:45096] def: "A sesamoid bone that is part of a pes." [OBOL:automatic] [Term] id: UBERON:0008001 ! irregular bone name: irregular bone def: "The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid." [Wikipedia:Irregular_bone] synonym: "os irregulare" EXACT [] xref: FMA:7477 ! irregular bone is_a: UBERON:0001474 {source="FMA"} ! bone element xref: ncithesaurus:Irregular_Bone ! Irregular Bone xref: SCTID:421560006 ! Entire irregular bone synonym: "os irregulare" RELATED LATIN [Wikipedia:Irregular_bone] xref: UMLS:C0502414 [Term] id: UBERON:0010428 name: flat bone def: "Flat bones are those bones which are found where the principal requirement is either extensive protection or the provision of broad surfaces for muscular attachment, the bones are expanded into broad, flat plates, as in the cranium, the ilium, sternum, rib cage, the sacrum and the scapula. These bones are composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow. In an adult, most red blood cells are formed in flat bones. In the cranial bones, the layers of compact tissue are familiarly known as the tables of the skull; the outer one is thick and tough; the inner is thin, dense, and brittle, and hence is termed the vitreous table. The intervening cancellous tissue is called the diploC+, and this, in certain regions of the skull, becomes absorbed so as to leave spaces filled with air (air-sinuses) between the two tables. The flat bones are: the occipital, parietal, frontal, nasal, lacrimal, vomer, scapula, os coxC&, sternum, and ribs." [Wikipedia:Flat_bone] is_a: UBERON:0001474 {source="FMA"} ! bone element xref: FMA:7476 ! flat bone xref: ncithesaurus:Flat_Bone ! flat bone xref: SCTID:332907008 ! Entire flat bone synonym: "os planum" RELATED LATIN [Wikipedia:Flat_bone] xref: galen:FlatBone ! flat bone xref: UMLS:C0222649 [Term] id: UBERON:0008199 name: chin def: "Surface structure that is the anteriormost part of the lower jaw region. In humans, the chin is the lowermost part of the face. It is formed by the lower front of the mandible. People show a wide variety of chin structures. See Cleft chin. The chin developed as a point of muscular attachment facilitating minute movements of the lips associated with speech. In human evolution, the chin is a cladistic apomorphy, partially defining anatomically modern Humans as distinct from archaic forms." [Wikipedia:Chin, TAO:0002254] synonym: "chins" RELATED [Wikipedia:Chin] synonym: "mental part of face" EXACT [FMA:46495] synonym: "mental region" EXACT [FMA:46495] synonym: "mental region of face" EXACT [FMA:46495] xref: FMA:46495 ! chin xref: MESH:A01.456.505.259 ! chin xref: GAID:67 ! chin xref: TAO:0002254 ! chin is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0001456 {source="MESH"} ! face relationship: part_of UBERON:0001710 {source="FMA"} ! lower jaw region synonym: "regio mentalis" EXACT LATIN [FMA:TA, FMA:46495] xref: galen:Chin xref: SCTID:362632004 ! Entire chin synonym: "mentum" RELATED LATIN [Wikipedia:Chin] xref: http://upload.wikimedia.org/wikipedia/commons/6/60/Gray1195.png property_value: external_definition "Surface structure that is the anteriormost region of the lower jaw.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002254", date_retrieved="2012-08-14", source="TAO:wd"} property_value: has_relational_adjective "mental" xsd:string [Term] id: UBERON:0008200 name: forehead def: "The part of the face above the eyes[MESH]. In human anatomy, the forehead is the fore part of the head. It is, formally, an area of the head bounded by three features, two of the skull and one of the scalp. The top of the forehead is marked by the hairline, the edge of the area where hair on the scalp grows. The bottom of the forehead is marked by the supraorbital ridge, the bone feature of the skull above the eyes. The two sides of the forehead are marked by the temporal ridge, a bone feature that links the supraorbital ridge to the coronal suture line and beyond[WP]." [MESH:A01.456.505.580, Wikipedia:Forehead] synonym: "fore head" RELATED [Wikipedia:Forehead] xref: FMA:63864 ! forehead xref: MESH:A01.456.505.580 ! forehead xref: GAID:74 ! forehead is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0001456 {source="FMA"} ! face xref: galen:Forehead xref: SCTID:362614004 ! Entire forehead xref: ncithesaurus:Forehead ! forehead synonym: "sinciput" RELATED LATIN [Wikipedia:Forehead] xref: http://upload.wikimedia.org/wikipedia/commons/8/83/Forhead_01_ies.jpg xref: UMLS:C0016540 [Term] id: UBERON:0008269 name: nacre def: "an organic-inorganic composite material produced by some mollusks as an inner shell layer; it is also what makes up pearls. It is very strong, resilient, and iridescent. Nacre is found in some ancient lineages of bivalve gastropod and cephalopod. The inner layer in the great majority of mollusk shells is porcellaneous, not nacreous, frequently resulting in a non-iridescent shine or less commonly in non-nacreous iridescence such as flame structure (e.g. conch pearl). Pearls and the inside layer of pearl oyster and freshwater pearl mussel shells are made of nacre. Many other families of mollusk also have a nacreous inner shell layer, including marine gastropods such as the Haliotidae, the Trochidae and the Turbinidae. Nacre is composed of hexagonal platelets of aragonite (a form of calcium carbonate) 10-20 µm wide and 0.5 µm thick arranged in a continuous parallel lamina. These layers are separated by sheets of organic matrix composed of elastic biopolymers (such as chitin, lustrin and silk-like proteins)[WP]." [Wikipedia:Nacre] synonym: "mother of pearl" EXACT [Wikipedia:Nacre] is_a: UBERON:0004755 ! skeletal tissue is_a: UBERON:0000463 ! portion of organism substance relationship: only_in_taxon NCBITaxon:6447 ! Mollusca [Term] id: UBERON:0008270 ! mollusc shell name: mollusc shell def: "a calcareous exoskeleton which encloses, supports and protects the soft parts of an animal in the phylum Mollusca, which includes snails, clams, tusk shells, and several other classes. Not all shelled molluscs live in the sea, many live on the land and in freshwater." [Wikipedia:Mollusc_shell] is_a: UBERON:0006612 ! shell relationship: only_in_taxon NCBITaxon:6447 ! Mollusca [Term] id: UBERON:0008271 ! turtle shell name: turtle shell def: "a highly complicated shield for the ventral and dorsal parts of the turtle, completely enclosing all the vital organs of the turtle and in some cases even the head. It is constructed of modified bony elements such as the ribs, parts of the pelvis and other bones found in most reptiles. The bone of the shell consists of both skeletal and dermal bone, showing that the complete enclosure of the shell probably evolved by including dermal armor into the rib cage.[WP]." [Wikipedia:Turtle_shell#Shell] is_a: UBERON:0006612 ! shell is_a: UBERON:0000075 ! subdivision of skeletal system relationship: only_in_taxon NCBITaxon:8459 ! Testudines [Term] id: UBERON:0008274 name: mollusc venom def: "Venoms from mollusks, including the Conus and Octopus species. The venoms contain proteins, enzymes, choline derivatives, slow-reacting substances, and several characterized polypeptide toxins that affect the nervous system. Mollusk venoms include cephalotoxin, venerup in, maculotoxin, surugatoxin, conotoxins, and murexine." [MESH:D24.185.926.580.590] synonym: "conus venom" RELATED [MESH:D24.185.926.580.590] synonym: "mollusc venom" RELATED [MESH:D24.185.926.580.590] synonym: "mollusk venom" RELATED [MESH:D24.185.926.580.590] synonym: "octopus venom" RELATED [MESH:D24.185.926.580.590] synonym: "snail venom" RELATED [MESH:D24.185.926.580.590] is_a: UBERON:0007113 {source="MESH"} ! venom relationship: only_in_taxon NCBITaxon:6447 ! Mollusca xref: MESH:D24.185.926.580.590 ! mollusk venom [Term] id: UBERON:0008275 name: carapace def: "Dorsal subdivision of turtle shell, consisting of the animal's ribcage combined with dermal bone[WP, modified]." [Wikipedia:Carapace#Turtles_and_tortoises] comment: note BTO class is more general is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0008271 ! turtle shell xref: BTO:0001701 ! carapace (also: UBERON:0008276 'plastron') [Term] id: UBERON:0008276 name: plastron def: "A composite bony plate forming the floor of the shell of a turtle consisting of fused dermal elements, including contributions from the clavicles (epiplastrons) and interclavice (epiplastron)." [Wikipedia:Wikipedia:Turtle_shell#Plastron, ISBN10:0073040584] comment: note BTO class is more general is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0008271 ! turtle shell xref: BTO:0001701 ! carapace (also: UBERON:0008275 'carapace') xref: SCTID:64243001 ! Plastron [Term] id: UBERON:0011657 ! dermal element of plastron name: dermal element of plastron def: "Fused ventral dermal element constituting the plastron." [ISBN10:0073040584] synonym: "plastral plate" RELATED [ISBN10:0073040584] is_a: UBERON:0008907 ! dermal bone relationship: part_of UBERON:0008276 ! plastron [Term] id: UBERON:0011658 name: epiplastron def: "Paired dermal bone that is part of the anterior region of the plastron. The epiplastron is found only in turtles. [PHENOSCAPE:ad]." [PHENOSCAPE:ad, PHENOSCAPE:mah, ISBN10:0073040584] comment: Derived ancestrally from the clavicle. synonym: "clavicle" RELATED [ISBN10:0073040584] is_a: UBERON:0011657 ! dermal element of plastron [Term] id: UBERON:0011659 name: entoplastron def: "A median bone at the anterior margin of the plastron." [ISBN10:0073040584] synonym: "interclavicle" RELATED [ISBN10:0073040584] is_a: UBERON:0011657 ! dermal element of plastron relationship: has_fused_element UBERON:0001105 ! clavicle [Term] id: UBERON:0011660 name: hypoplastron is_a: UBERON:0011657 ! dermal element of plastron [Term] id: UBERON:0011661 name: xiphiplastron is_a: UBERON:0011657 ! dermal element of plastron [Term] id: UBERON:0011662 ! plastron-carapice bridge name: plastron-carapice bridge synonym: "bridge struct" RELATED [] is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0008276 ! plastron [Term] id: UBERON:0011663 name: anterior plastron-carapice bridge synonym: "anterior bridge struct" RELATED [] is_a: UBERON:0011662 ! plastron-carapice bridge [Term] id: UBERON:0011664 name: posterior plastron-carapice bridge synonym: "posterior bridge struct" RELATED [] is_a: UBERON:0011662 ! plastron-carapice bridge [Term] id: UBERON:0011665 ! carapace bone name: carapace bone def: "Fused dorsal element constituting the carapace of a turtle shell." [ISBN10:0073040584] comment: The carapace contains a mix of dermal bone and rib cage synonym: "carapace plate" RELATED [] is_a: UBERON:0001474 ! bone element relationship: part_of UBERON:0008275 ! carapace [Term] id: UBERON:0011666 name: peripheral plate of carapace def: "One of a series of bones around the edge of the carapace." [ISBN10:0073040584] is_a: UBERON:0011665 ! carapace bone [Term] id: UBERON:0011667 name: pleural plate of carapace def: "One of eight pairs of plates on the carapace, forming two rows adjacent to the peripheral plates." [ISBN10:0073040584] comment: A combination of ribs and fused dermal bone[WP] is_a: UBERON:0011665 ! carapace bone [Term] id: UBERON:0011668 name: nuchal plate of carapace def: "." [ISBN10:0073040584] is_a: UBERON:0011665 ! carapace bone [Term] id: UBERON:0011669 name: neural plate of carapace def: "One of a series of plates on the dorsal midline of the turtle shell, posterior to the nuchal bone." [ISBN10:0073040584] comment: In many species of Pleurodire they are submerged below the pleurals[WP] is_a: UBERON:0011665 ! carapace bone [Term] id: UBERON:0011670 name: pygal plate of carapace def: "One of three plates on the posterior end of the carapace, posterior to the neural plates." [ISBN10:0073040584] is_a: UBERON:0011665 ! carapace bone [Term] id: UBERON:0011671 name: nuchal bone def: "A single bone on the anterior end of the carapace." [ISBN10:0073040584] is_a: UBERON:0011665 ! carapace bone [Term] id: UBERON:0011672 name: suprapygal bone def: "." [ISBN10:0073040584] is_a: UBERON:0011665 ! carapace bone [Term] id: UBERON:0011673 name: plastron scute intersection_of: UBERON:0008201 ! scute intersection_of: part_of UBERON:0008276 ! plastron def: "A scute that is part of a plastron." [OBOL:automatic] [Term] id: UBERON:0011674 name: carapace scute intersection_of: UBERON:0008201 ! scute intersection_of: part_of UBERON:0008275 ! carapace def: "A scute that is part of a carapace." [OBOL:automatic] [Term] id: UBERON:0008277 ! cnida name: cnida synonym: "cnidae" EXACT PLURAL [] is_a: UBERON:0000470 ! cell part [Term] id: UBERON:0008278 name: nematocyst def: "One of the stinging organelles of coelenterates used in catching prey." [BTO:0000918] xref: BTO:0000918 ! nematocyst is_a: UBERON:0008277 ! cnida [Term] id: UBERON:0008279 name: spirocyst is_a: UBERON:0008277 ! cnida [Term] id: UBERON:0008280 name: cnidarian venom def: "Venoms from jellyfish, corals, SEA ANEMONES, etc. They contain hemo-, cardio-, dermo- , and neurotoxic substances and probably ENZYMES. They include palytoxin, sarcophine, and anthopleurine." [MESH:D24.185.926.580.230] synonym: "chironex venom" RELATED [MESH:D24.185.926.580.230] synonym: "cnidarian venom" RELATED [MESH:D24.185.926.580.230] synonym: "jellyfish venom" RELATED [MESH:D24.185.926.580.230] synonym: "portuguese man of war venom" RELATED [MESH:D24.185.926.580.230] synonym: "portuguese man-of-war venom" RELATED [MESH:D24.185.926.580.230] synonym: "sea anemone venom" RELATED [MESH:D24.185.926.580.230] is_a: UBERON:0007113 {source="MESH"} ! venom xref: MESH:D24.185.926.580.230 ! cnidarian venom [Term] id: UBERON:0008283 ! columnella name: columnella def: "a central anatomical feature of a coiled snail shell or gastropod shell. It is often only clearly visible as a structure when the shell is broken, or sliced in half vertically, or in an X-ray." [Wikipedia:Columella_(gastropod)] disjoint_from: UBERON:0008341 ! columella nasi disjoint_from: UBERON:0001687 ! stapes is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0008270 ! mollusc shell relationship: only_in_taxon NCBITaxon:6447 ! Mollusca [Term] id: UBERON:0008284 name: columnella muscle def: "The muscle of the central column or axis of a spiral univalve shell." [BTO:0000277, Wikipedia:Columella_(gastropod)#Columellar_muscles] synonym: "columella muscle" RELATED [BTO:0000277] xref: BTO:0000277 ! columnella muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0008283 ! columnella [Term] id: UBERON:0008337 name: inguinal part of abdomen def: "The external junctural region between the lower part of the abdomen and the thigh." [MESH:A01.047.365] comment: galen treats inguinal region and groin as distinct synonym: "iliac region" RELATED [BTO:0003358] synonym: "inguen" RELATED [BTO:0003358] synonym: "inguinal region" RELATED [BTO:0003358] synonym: "groin" EXACT [FMA:24040] synonym: "iliac fossa viewed surgically" EXACT [FMA:24040] synonym: "iliac region" EXACT [FMA:24040] synonym: "inguen" EXACT LATIN [FMA:TA] synonym: "inguinal region" EXACT [FMA:24040] xref: FMA:24040 ! inguinal part of abdomen xref: BTO:0003358 ! groin xref: MESH:A01.047.365 xref: GAID:27 ! groin is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0002417 ! abdominal segment of trunk xref: ncithesaurus:Inguinal_Region ! Inguinal Region xref: galen:InguinalRegion xref: SCTID:243962005 ! Entire inguinal region xref: EFO:0001397 ! inguinal region xref: UMLS:C0018246 [Term] id: UBERON:0011015 name: iliac fossa xref: FMA:75316 ! iliac fossa is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001273 ! ilium xref: SCTID:182341009 ! Entire iliac fossa [Term] id: UBERON:0008837 ! palmar/plantar part of autopod name: palmar/plantar part of autopod is_a: UBERON:0002529 ! limb segment relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0012348 ! autopod pad name: autopod pad def: "thin, pigmented, keratinised, hairless epidermis covering subcutaneous, collagenous, and adipose tissue." [UBERON:cjm, http://en.wikipedia.org/wiki/Paw#Common_characteristics] synonym: "paw pad" RELATED [] is_a: UBERON:0000014 ! zone of skin relationship: part_of UBERON:0002470 ! autopod region relationship: has_part UBERON:0002190 ! subcutaneous adipose tissue relationship: has_part UBERON:0001003 ! epidermis xref: http://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Paw_and_pads.jpg/250px-Paw_and_pads.jpg [Term] id: UBERON:0012349 name: digital pad def: "A thick spongy structure at the base of the paw, centred over the flexor surfaces of the distal interphalangeal joints." [MURDOCH:611] comment: May be fused synonym: "interdigital pad" EXACT [] synonym: "acropodial pad" EXACT [] synonym: "acropodium pad" EXACT [] synonym: "digital cushion" RELATED [] synonym: "digital pads" RELATED PLURAL [] intersection_of: UBERON:0012348 ! autopod pad intersection_of: part_of UBERON:0012354 ! acropodium region [Term] id: UBERON:0012350 name: carpal pad def: "An autopod pad found in the carpal region of a paw. Used for additional traction when stopping or descending a slope in digitigrade species." [UBERON:cjm] intersection_of: UBERON:0012348 ! autopod pad intersection_of: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0008838 ! metapodial pad name: metapodial pad def: "A thick, spongy layer of tissue located under the metacarpal and metatarsal joints of the foot" [ncithesaurus:Footpad] comment: Editor notes: check synonyms - re footpad synonym: "foot pad" RELATED [] synonym: "metapodium pad" RELATED [] synonym: "foot pad" RELATED [] synonym: "footpad" RELATED [] intersection_of: UBERON:0012348 ! autopod pad intersection_of: part_of UBERON:0009877 ! metapodium region xref: ncithesaurus:Footpad ! footpad [Term] id: UBERON:0008839 name: palmar pad def: "An autopod pad that is in the metacarpal region" [UBERON:cjm] comment: note that the EMAPA term refers to the plural synonym: "palmar pads" RELATED PLURAL [EMAPA:18489] synonym: "metacarpal pad" RELATED [] synonym: "metacarpal foot pad" RELATED [] intersection_of: UBERON:0008838 ! metapodial pad intersection_of: part_of UBERON:0004453 ! metacarpus region relationship: part_of UBERON:0001519 {source="EMAPA"} ! skin of manus relationship: part_of UBERON:0008878 {source="cjm"} ! palmar part of manus xref: EMAPA:18489 ! palmar pads [Term] id: UBERON:0008840 name: plantar pad def: "An autopod pad that is in the metatarsal region" [UBERON:cjm] synonym: "plantar pads" RELATED PLURAL [EMAPA:18507] synonym: "metatarsal pad" RELATED [] synonym: "metatarsal foot pad" RELATED [] intersection_of: UBERON:0008838 ! metapodial pad intersection_of: part_of UBERON:0000983 ! metatarsus region relationship: part_of UBERON:0001513 {source="EMAPA"} ! skin of pes relationship: part_of UBERON:0008338 {source="cjm"} ! plantar part of pes xref: EMAPA:18507 ! plantar pads property_value: external_definition "The canine metatarsal pad is large and heart-shaped, and functions to cushion the foot. The pad is covered by a naked, densely cornified epidermis, which is usually highly pigmented and is the toughest region of the canine skin. The digital cushion or bulk of the foot pad is composed of a subcutaneous adipose tissue, partitioned by reticular, collagenous and elastic fibres. The subcutis of the canine footpads contains sweat glands embedded in the adipose tissue. The ducts of these glands channel through the thick epidermis of the foot pad. The secretions from these glands function as territorial or trail markers[MURDOCH:1334]." xsd:string {source="MURDOCH:1334"} [Term] id: UBERON:0008338 ! plantar part of pes name: plantar part of pes def: "The sole is the bottom of the foot. In humans is the sole of the foot anatomically referred to as the plantar aspect. The equivalent surface in ungulates is the hoof." [Wikipedia:Sole_%28foot%29] synonym: "pelma" RELATED [Wikipedia:Sole_%28foot%29] synonym: "sole of foot" RELATED [Wikipedia:Sole_%28foot%29] synonym: "sole of the foot" RELATED [Wikipedia:Sole_%28foot%29] synonym: "soles of the feet" RELATED [Wikipedia:Sole_%28foot%29] synonym: "planta" EXACT LATIN [FMA:TA] synonym: "plantar region" EXACT [FMA:25000] synonym: "regio plantaris" EXACT LATIN [FMA:TA] synonym: "sole" EXACT [FMA:25000] synonym: "sole of foot" EXACT [FMA:25000] is_a: UBERON:0005445 {source="FMA"} ! segment of pes is_a: UBERON:0008837 ! palmar/plantar part of autopod xref: FMA:25000 ! plantar part of foot xref: BTO:0005078 ! foot sole xref: ncithesaurus:Plantar_Region ! Plantar Region xref: galen:SoleOfFoot xref: SCTID:57999000 ! Structure of sole of foot synonym: "planta" RELATED LATIN [Wikipedia:Sole_%28foot%29] xref: http://upload.wikimedia.org/wikipedia/commons/4/41/Soles2.jpg synonym: "plantar part of foot" EXACT [FMA:25000] xref: UMLS:C0230463 [Term] id: UBERON:0008878 name: palmar part of manus synonym: "front of hand" EXACT [FMA:24920] synonym: "palm of hand" EXACT [FMA:24920] synonym: "palmar region" EXACT [FMA:24920] synonym: "regio palmaris" EXACT LATIN [FMA:TA] synonym: "palm" EXACT [FMA:24920] is_a: UBERON:0005451 {source="FMA"} ! segment of manus is_a: UBERON:0008837 ! palmar/plantar part of autopod xref: FMA:24920 ! palm xref: ncithesaurus:Palmar_Region ! Palmar Region xref: galen:Palm ! palm xref: UMLS:C0931849 [Term] id: UBERON:0013622 name: manual autopod pad intersection_of: UBERON:0012348 ! autopod pad intersection_of: part_of UBERON:0002398 ! manus synonym: "manual foot pad" RELATED [] synonym: "foot pad of manus" RELATED [] [Term] id: UBERON:0013623 name: pedal autopod pad intersection_of: UBERON:0012348 ! autopod pad intersection_of: part_of UBERON:0002387 ! pes synonym: "pedal foot pad" RELATED [] synonym: "foot pad of pes" RELATED [] [Term] id: UBERON:0013626 name: medial metatarsal pad synonym: "thenar pad" EXACT [] is_a: UBERON:0008840 ! plantar pad [Term] id: UBERON:0013627 name: lateral metatarsal pad synonym: "hypothenar pad" EXACT [] is_a: UBERON:0008840 ! plantar pad [Term] id: UBERON:0013628 name: pollical pad synonym: "interdigital pad 1 of manus" EXACT [] is_a: UBERON:0012349 ! digital pad relationship: part_of UBERON:0001463 ! manual digit 1 [Term] id: UBERON:0013629 name: hallical pad synonym: "interdigital pad 1 of pes" EXACT [] is_a: UBERON:0012349 ! digital pad relationship: part_of UBERON:0003631 ! pedal digit 1 [Term] id: UBERON:0008339 name: microvascular endothelium is_a: UBERON:0004852 {source="BTO"} ! cardiovascular system endothelium xref: BTO:0003122 ! microvascular endothelium [Term] id: UBERON:0008340 ! nasal bridge name: nasal bridge def: "A saddle-shaped area that includes the nasal root and the lateral aspects of the nose. It lies between the glabella and the inferior boundary of the nasal bone, and extends laterally to the inner canth[WP]." [Wikipedia:Nasal_bridge, http://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.32600/full] is_a: UBERON:0000061 {source="AEO"} ! anatomical structure relationship: part_of UBERON:0006333 {source="MA"} ! snout relationship: part_of UBERON:0001456 ! face relationship: part_of UBERON:0000004 ! olfactory apparatus xref: MA:0002874 ! nasal bridge [Term] id: UBERON:0008367 name: breast epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000310 ! breast xref: BTO:0001428 ! breast epithelium def: "An epithelium that is part of a breast." [OBOL:automatic] [Term] id: UBERON:0008397 name: tracheobronchial epithelium def: "Epithelium pertaining to the trachea and bronchi." [Dorlands_Medical_Dictionary:MerckMedicus] synonym: "bronchotracheal epithelium" RELATED [BTO:0002925] is_a: UBERON:0004802 {source="BTO"} ! respiratory tract epithelium xref: BTO:0002925 ! tracheobronchial epithelium [Term] id: UBERON:0008404 name: proximale tubular epithelium def: "The cells lining the proximal tubule are cuboidal epithelial cells with deep basal membrane invaginations that provide a large basal surface area. The long microvilli (the brush border) lining the tubule lumen, maximize luminal surface area and make these cells ideally suited for both reabsorptive and secretory functions." [Renal_Physiology:Section_7,_Chapter_3] synonym: "proximale tubule epithelium" RELATED [BTO:0003576] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004134 ! proximal tubule relationship: part_of UBERON:0004134 {source="BTO"} ! proximal tubule xref: BTO:0003576 ! proximale tubular epithelium [Term] id: UBERON:0008408 name: distal tubular epithelium synonym: "distal tubule epithelium" RELATED [BTO:0003948] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004135 ! distal tubule relationship: part_of UBERON:0004135 {source="BTO"} ! distal tubule xref: BTO:0003948 ! distal tubular epithelium def: "An epithelium that is part of a distal tubule." [OBOL:automatic] [Term] id: UBERON:0008420 name: buccal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006956 ! buccal mucosa relationship: part_of UBERON:0006956 {source="BTO"} ! buccal mucosa xref: BTO:0004803 ! buccal epithelium def: "An epithelium that is part of a buccal mucosa." [OBOL:automatic] [Term] id: UBERON:0000180 name: lateral lumbar region of abdomen def: "a region of the posterior torso (lower back) beneath the ribs and above the ilium." [Wikipedia:Abdomen#9-region_scheme, Wikipedia:Latus_(anatomy)] is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000916 ! abdomen synonym: "flank" EXACT [Wikipedia:Latus_(anatomy)] synonym: "lateral region" EXACT [FMA:14603] synonym: "lateral region of abdomen" EXACT [FMA:14603] synonym: "regio lateralis" EXACT [FMA:14603] synonym: "latus" EXACT [FMA:14603] xref: FMA:14603 ! lateral lumbar region of abdomen xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray1220.png xref: galen:Flank xref: SCTID:243329008 ! Entire lateral region of abdomen xref: ncithesaurus:Flank ! flank xref: UMLS:C0230171 [Term] id: UBERON:0000569 name: ileocecal valve def: "The ileocecal valve is a sphincter muscle situated at the junction of the small intestine (ileum) and the large intestine. Its critical function is to limit the reflux of colonic contents into the ileum." [Wikipedia:Ileocecal_valve] is_a: UBERON:0003978 {source="Obol"} ! valve is_a: UBERON:0004590 {source="Wikipedia"} ! sphincter muscle relationship: part_of UBERON:0001073 {source="FMA"} ! ileocecal junction synonym: "valva ileocaecalis (valva ilealis)" EXACT [FMA:15973] synonym: "Tulp's valve" RELATED [Wikipedia:Ileocecal_valve] xref: FMA:15973 ! ileocecal valve xref: ncithesaurus:Ileocecal_Valve ! Ileocecal Valve xref: galen:IleocecalValve xref: SCTID:362153007 ! Entire ileocecal valve synonym: "valva ileocaecalis" RELATED LATIN [Wikipedia:Ileocecal_valve] xref: http://upload.wikimedia.org/wikipedia/commons/f/fc/Gray1075.png xref: UMLS:C0020880 [Term] id: UBERON:0008841 ! suspensory ligament name: suspensory ligament is_a: UBERON:0008845 ! nonskeletal ligament def: "A ligament that supports a body part, especially an organ." [Wikipedia:Cooper%27s_ligaments_of_penis] [Term] id: UBERON:0000642 name: suspensory ligament of duodenum def: "Ligament that connects the duodenum of the small intestines to the diaphragm. It contains a slender band of skeletal muscle from the diaphragm and a fibromuscular band of smooth muscle from the horizontal and ascending parts of the duodenum. When it contracts, the suspensory muscle of the duodenum widens the angle of the duodenojejunal flexure, allowing movement of the intestinal contents It arises from the right crus as it passes around the esophagus, continues as connective tissue around the stems of the celiac trunk and superior mesenteric artery and inserts into the third and fourth portions of the duodenum and frequently into the duodenojejunal (DJ) flexure (between the duodenum and the jejunum) as well. " [Wikipedia:Suspensory_muscle_of_duodenum] comment: an especially important landmark to note when looking at the bowel for the presence of malrotation of the gut, a syndrome often suspected in young children when they have episodes of recurrent vomiting. Visualizing a normal location of the ligament of Treitz in radiological images is critical in ruling out malrotation of the gut in a child; it is abnormally located when malrotation is present. An abnormally low and fixed position of the ligament of Treitz is a known cause of superior mesenteric artery syndrome. However, identifying it on a CT scan is difficult. Hematemesis (blood in the vomit) or melena (black tarry stools) usually indicate a gastrointestinal bleed from a location proximal to the ligament. Hematochezia (bright red blood or clots in the stools) usually indicates a gastrointestinal bleed from a location distal to the ligament. synonym: "ligament of Treitz" EXACT [FMA:20509] synonym: "muscle of Treitz" EXACT [FMA:20509] synonym: "suspensory muscle of duodenum" EXACT [FMA:20509] synonym: "musculus suspensorius duodeni" EXACT [FMA:20509] xref: FMA:20509 ! suspensory ligament of duodenum is_a: UBERON:0008841 {source="Obol"} ! suspensory ligament relationship: attaches_to UBERON:0002114 {source="Obol"} ! duodenum relationship: attaches_to UBERON:0001103 {source="Obol"} ! diaphragm intersection_of: UBERON:0008841 ! suspensory ligament intersection_of: attaches_to UBERON:0002114 ! duodenum xref: SCTID:279979000 ! Entire suspensory muscle of duodenum synonym: "musculus suspensorius duodeni" RELATED LATIN [Wikipedia:Suspensory_muscle_of_duodenum] xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Gray1042.png [Term] id: UBERON:0011220 name: mastoid process of temporal bone def: "The mastoid process is a conical prominence projecting from the undersurface of the mastoid portion of the temporal bone. It is located just behind the external acoustic meatus, and lateral to the styloid process. Its size and form vary somewhat; it is larger in the male than in the female. This process serves for the attachment of the posterior belly of the digastric, sternocleidomastoid, splenius capitis, and longissimus capitis muscles. The word is derived from the Greek 'masto-', alluding to its resemblance to the breast." [Wikipedia:Mastoid_process] synonym: "mastoid" RELATED [Wikipedia:Mastoid_process] synonym: "processus mastoideus ossis temporalis" RELATED [Wikipedia:Mastoid_process] synonym: "mastoid process" EXACT [FMA:52872] synonym: "mastoid process of skull" EXACT [] xref: FMA:52872 ! mastoid process xref: ncithesaurus:Mastoid_Process ! mastoid process xref: SCTID:304336002 ! Entire mastoid process of skull is_a: UBERON:0000075 {source="ncithesaurus"} ! subdivision of skeletal system relationship: part_of UBERON:0001678 {source="ncithesaurus"} ! temporal bone xref: UMLS:C0446908 [Term] id: UBERON:0000711 name: splenius capitis def: "The splenius capitis is a broad, straplike muscle in the back of the neck. It pulls on the base of the skull from vertebrae in the neck and upper thorax. It arises from the lower half of the ligamentum nuchæ, from the spinous process of the seventh cervical vertebra, and from the spinous processes of the upper three or four thoracic vertebræ. The fibers of the muscle are directed upward and lateralward and are inserted, under cover of the Sternocleidomastoideus, into the mastoid process of the temporal bone, and into the rough surface on the occipital bone just below the lateral third of the superior nuchal line. The Splenius Capitis muscle is innervated by the dorsal rami of spinal nerves C3-C4. The splenius muscle is a prime mover for head extension. The splenius capitis can also allow lateral flexion and rotation of the cervical spine." [Wikipedia:Splenius_capitis_muscle] is_a: UBERON:0002252 {source="FMA"} ! splenius relationship: part_of UBERON:0000974 ! neck synonym: "splenius capitis muscle" EXACT [Wikipedia:Splenius_capitis_muscle] xref: FMA:22653 ! splenius capitis xref: SCTID:244850004 ! Entire splenius capitis muscle synonym: "musculus splenius capitis" RELATED LATIN [Wikipedia:Splenius_capitis_muscle] relationship: has_muscle_origin UBERON:0000351 {source="dbpedia", notes="Ligamentum nuchae spinous process of C7-T6"} ! nuchal ligament relationship: has_muscle_insertion UBERON:0011220 {source="Wikipedia:Mastoid_process"} ! mastoid process of temporal bone xref: http://upload.wikimedia.org/wikipedia/commons/5/51/Splenius.png [Term] id: UBERON:0000144 name: trochlea of humerus def: "The medial portion of the articular surface of the humerus is named the trochlea, and presents a deep depression between two well-marked borders; it is convex from before backward, concave from side to side, and occupies the anterior, lower, and posterior parts of the extremity. It is directly inferior to the most prominent anterior humeral fossia, the Coronoid fossia. It articulates with the ulna." [Wikipedia:Trochlea_of_humerus] is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0004404 ! distal epiphysis of humerus synonym: "humeral trochlea" EXACT [FMA:23370] xref: FMA:23370 ! trochlea of humerus xref: SCTID:282817004 ! Entire trochlea of humerus xref: http://upload.wikimedia.org/wikipedia/commons/4/4b/Trochleahumeri.png [Term] id: UBERON:0000199 name: neck of radius def: "the narrow part of the shaft of the radius just below the head." [http://www.medilexicon.com/medicaldictionary.php?t=58913] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0004413 {source="FMA"} ! proximal epiphysis of radius synonym: "radial neck" EXACT [FMA:23479] xref: FMA:23479 ! neck of radius xref: galen:NeckOfRadius xref: SCTID:181942005 ! Entire neck of radius [Term] id: UBERON:0000218 name: vertebral arch of axis synonym: "vertebral foramen of cervical vertebra 2" EXACT [] intersection_of: UBERON:0003861 ! vertebral arch intersection_of: part_of UBERON:0001093 ! cervical vertebra 2 xref: FMA:24053 ! vertebral arch of axis def: "A neural arch that is part of a cervical vertebra 2." [OBOL:automatic] [Term] id: UBERON:0008437 name: posterior arch of atlas def: "In a cervical vertebra, the posterior arch forms about two-fifths of the circumference of the ring: it ends behind in the posterior tubercle, which is the rudiment of a spinous process and gives origin to the Recti capitis posteriores minores." [Wikipedia:Posterior_arch_of_atlas] synonym: "posterior arch" RELATED [Wikipedia:Posterior_arch] is_a: UBERON:0008434 {source="FMA"} ! cervical vertebral arch relationship: part_of UBERON:0001092 {source="FMA"} ! cervical vertebra 1 xref: FMA:23977 ! posterior arch of atlas xref: SCTID:181892007 ! Entire posterior arch of atlas xref: http://upload.wikimedia.org/wikipedia/commons/6/6b/Arcusposterioratlantis.png [Term] id: UBERON:0000219 name: vertebral foramen of atlas def: "." [Wikipedia:Atlas_(anatomy)#Vertebral_foramen] synonym: "vertebral foramen of cervical vertebra 1" EXACT [] intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0001092 ! cervical vertebra 1 xref: FMA:24293 ! vertebral foramen of atlas xref: SCTID:281228008 ! Vertebral foramen of atlas [Term] id: UBERON:0000221 name: supraauricular point def: "a craniometric point on the posterior root of the zygomatic process of the temporal bone directly above the auricular point." [http://www.medilexicon.com/medicaldictionary.php?t=70620] is_a: UBERON:0006983 {source="FMA"} ! anatomical point xref: FMA:224222 ! supra-auricular part of head synonym: "supra-auricular part of head" EXACT [FMA:224222] [Term] id: UBERON:0001010 name: diaphysis of ulna def: "The body of the ulna at its upper part is prismatic in form, and curved so as to be convex behind and lateralward; its central part is straight; its lower part is rounded, smooth, and bent a little lateralward. It tapers gradually from above downward, and has three borders and three surfaces." [Wikipedia:Body_of_ulna] synonym: "shaft of ulna" RELATED [Wikipedia:Body_of_ulna] synonym: "supinator crest" RELATED [Wikipedia:Body_of_ulna] intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0001424 ! ulna synonym: "body of ulna" EXACT [FMA:33760] synonym: "shaft of ulna" EXACT [FMA:33760] synonym: "ulnar diaphysis" EXACT [FMA:33760] synonym: "corpus ulnae" EXACT [FMA:33760] xref: FMA:33760 ! diaphysis of ulna xref: SCTID:302520004 ! Entire shaft of ulna [Term] id: UBERON:0001012 name: head of radius def: "The head of the radius has a cylindrical form, and on its upper surface is a shallow cup or fovea for articulation with the capitulum (or capitellum) of the humerus. The circumference of the head is smooth; it is broad medially where it articulates with the radial notch of the ulna, narrow in the rest of its extent, which is embraced by the annular ligament. The deepest point in the fovea is not axi-symmetric with the long axis of the radius, creating a cam effect during pronation and supination[WP]." [Wikipedia:Head_of_radius] is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0001490 {source="FMA"} ! elbow joint relationship: part_of UBERON:0004413 {source="FMA"} ! proximal epiphysis of radius synonym: "radial head" EXACT [FMA:33773] xref: FMA:33773 ! head of radius xref: galen:HeadOfRadius xref: SCTID:181941003 ! Entire head of radius synonym: "caput radii" RELATED LATIN [Wikipedia:Head_of_radius] xref: http://upload.wikimedia.org/wikipedia/commons/4/47/Gray214.png [Term] id: UBERON:0001028 name: diaphysis of radius def: "A diaphysis that is part of a radius bone[Automatically generated definition]." [OBOL:automatic, Wikipedia:Body_of_radius] synonym: "radial shaft" RELATED [Wikipedia:Body_of_radius] synonym: "shaft of radius" RELATED [Wikipedia:Body_of_radius] intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0001423 ! radius synonym: "body of radius" EXACT [FMA:33782] synonym: "radial diaphysis" EXACT [FMA:33782] synonym: "shaft of radius" EXACT [FMA:33782] synonym: "corpus radii" EXACT [FMA:33782] xref: FMA:33782 ! diaphysis of radius xref: SCTID:302518002 ! Entire shaft of radius property_value: external_definition "The body of the radius (or shaft of radius) is prismoid in form, narrower above than below, and slightly curved, so as to be convex lateralward. It presents three borders and three surfaces[Wikipedia:Body_of_radius]." xsd:string {source="Wikipedia:Body_of_radius"} [Term] id: UBERON:0013280 name: diaphysis of tibia def: "A diaphysis that is part of a tibia." [OBOL:automatic, Wikipedia:Body_of_tibia] synonym: "body of the tibia" RELATED [Wikipedia:Body_of_tibia] synonym: "shaft of tibia" RELATED [Wikipedia:Body_of_tibia] synonym: "body of tibia" EXACT [FMA:33125] synonym: "corpus tibiae" EXACT [FMA:TA] synonym: "shaft of tibia" EXACT [FMA:33125] synonym: "tibial diaphysis" EXACT [FMA:33125] intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0000979 ! tibia xref: FMA:33125 ! diaphysis of tibia xref: SCTID:302525009 ! Entire shaft of tibia property_value: external_definition "The body of the tibia has three borders and three surfaces[Wikipedia:Body_of_tibia]." xsd:string {source="Wikipedia:Body_of_tibia"} [Term] id: UBERON:0002988 name: first dorsal interosseous of manus is_a: UBERON:0001503 {source="FMA"} ! dorsal interosseous of manus synonym: "abductor indicis" EXACT [FMA:37424] synonym: "first dorsal interosseous of hand" EXACT [FMA:37424] xref: FMA:37424 ! first dorsal interosseous of hand xref: SCTID:245003002 ! First dorsal interosseous of hand synonym: "first dorsal interosseous of hand" EXACT [FMA:37424] [Term] id: UBERON:0002989 name: anconeus muscle def: "small muscle on the posterior aspect of the elbow joint." [Wikipedia:Anconeus_muscle] comment: Some consider anconeus to be a continuation of the triceps brachii muscle. Some sources consider it to be part of the posterior compartment of the arm, while others consider it part of the posterior compartment of the forearm. is_a: UBERON:0004255 {source="FMA"} ! forelimb stylopod muscle synonym: "anconeus" EXACT [Wikipedia:Anconeus_muscle] xref: FMA:37704 ! anconeus xref: SCTID:244993003 ! Entire anconeus muscle relationship: innervated_by UBERON:0001492 {source="dbpedia"} ! radial nerve synonym: "musculus anconeus" RELATED LATIN [Wikipedia:Anconeus_muscle] relationship: has_muscle_insertion UBERON:0006810 {source="dbpedia", notes="lateral surface of the olecranon process and the superior part of the posterior ulna distally"} ! olecranon relationship: has_muscle_origin UBERON:0006807 {source="dbpedia", notes="lateral epicondyle of the humerus proximally"} ! ectepicondyle of humerus xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Gray1232.png xref: AAO:0010714 ! m. anconeus synonym: "m. anconeus" EXACT [AAO:0010714] [Term] id: UBERON:0003222 name: flexor digitorum superficialis def: "an extrinsic flexor muscle of the fingers at the proximal interphalangeal joints. The muscle has two classically described heads - the humeroulnar and radial - and it is between these heads that the median nerve and ulnar artery pass. The ulnar collateral ligament of elbow joint gives its origin to part of this muscle. The primary function of flexor digitorum superficialis is flexion of the middle phalanges of the fingers at the proximal interphalangeal joints, however under continued action it also flexes the metacarpophalangeal joints and wrist joint[WP]." [Wikipedia:Flexor_digitorum_superficialis_muscle] synonym: "flexor digitorum superficialis muscle" EXACT [Wikipedia:Flexor_digitorum_superficialis_muscle] is_a: UBERON:0004254 {source="FMA"} ! forelimb zeugopod muscle xref: FMA:38469 ! flexor digitorum superficialis relationship: innervated_by UBERON:0001148 {source="dbpedia"} ! median nerve relationship: has_muscle_antagonist UBERON:0007612 {source="dbpedia"} ! extensor digitorum communis synonym: "musculus flexor digitorum superficialis" RELATED LATIN [Wikipedia:Flexor_digitorum_superficialis_muscle] relationship: has_muscle_insertion UBERON:0004301 {source="dbpedia", notes="anterior margins on the bases of the middle phalanges of the four fingers"} ! middle phalanx relationship: has_muscle_origin UBERON:0006806 {source="dbpedia", notes="medial epicondyle of the humerus as well as parts of the radius and ulna."} ! medial epicondyle of humerus xref: http://upload.wikimedia.org/wikipedia/commons/5/53/Gray421.png [Term] id: UBERON:0003228 name: supinator muscle def: "a muscle which originates on the distal humerus, inserts on the radius and accomplishes supination (rotation of the wrist)." [Wikipedia:Supinator_muscle] comment: TODO: The term "supinator" can also refer more generally to a muscle that causes supination of a part of the body. In older texts, the term "supinator longus" was used to refer to the brachioradialis, and "supinator brevis" was used to the muscle now known as the supinator. is_a: UBERON:0004254 {source="FMA"} ! forelimb zeugopod muscle synonym: "supinator" EXACT [] synonym: "musculus supinator" RELATED LATIN [Wikipedia:Supinator_muscle] synonym: "supinator brevus" RELATED DEPRECATED [Wikipedia:Supinator_muscle] xref: FMA:38512 ! supinator xref: FMA:75002 ! supinator muscle xref: SCTID:181634007 ! Entire supinator muscle relationship: has_muscle_antagonist UBERON:0001520 {source="dbpedia"} ! pronator teres relationship: innervated_by UBERON:0001492 {source="dbpedia", notes="deep branch of radial nerve"} ! radial nerve relationship: has_muscle_origin UBERON:0006807 {source="dbpedia", notes="Lateral epicondyle of humerus supinator crest of ulna radial collateral ligament annular ligament"} ! ectepicondyle of humerus relationship: has_muscle_origin UBERON:0001424 {source="dbpedia", notes="Lateral epicondyle of humerus supinator crest of ulna radial collateral ligament annular ligament"} ! ulna relationship: has_muscle_insertion UBERON:0001423 {source="palaeos"} ! radius bone xref: http://upload.wikimedia.org/wikipedia/commons/c/c6/Gray420.png [Term] id: UBERON:0003234 name: extensor pollicis longus muscle def: "The Extensor pollicis longus is much larger than the Extensor pollicis brevis muscle, the origin of which it partly covers." [Wikipedia:Extensor_pollicis_longus_muscle] synonym: "extensor pollicis longis" RELATED [Wikipedia:Extensor_pollicis_longus_muscle] synonym: "extensor pollicis longus" EXACT [FMA:38521] xref: FMA:38521 ! extensor pollicis longus xref: SCTID:361820003 ! Entire extensor pollicis longus muscle is_a: UBERON:0011024 {source="Wikipedia"} ! extrinsic extensor muscle of manus relationship: has_muscle_insertion UBERON:0001463 {source="dbpedia"} ! manual digit 1 relationship: has_muscle_insertion UBERON:0004300 {source="dbpedia"} ! distal phalanx relationship: has_muscle_origin UBERON:0001424 {source="dbpedia"} ! ulna relationship: has_muscle_antagonist UBERON:0011012 {source="dbpedia"} ! flexor pollicis brevis muscle relationship: has_muscle_antagonist UBERON:0008446 {source="dbpedia"} ! flexor pollicis longus muscle synonym: "musculus extensor pollicis longus" RELATED LATIN [Wikipedia:Extensor_pollicis_longus_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/3/3e/Extensor_pollicis_longus_muscle.png [Term] id: UBERON:0003250 name: rectus capitis lateralis def: "The Rectus capitis lateralis, a short, flat muscle, arises from the upper surface of the transverse process of the atlas, and is inserted into the under surface of the jugular process of the occipital bone." [Wikipedia:Rectus_capitis_lateralis_muscle] synonym: "rectus capitis lateralis" RELATED [Wikipedia:Rectus_capitis_lateralis_muscle] synonym: "rectus capitus lateralis" RELATED [Wikipedia:Rectus_capitis_lateralis_muscle] synonym: "rectus capitus lateralis muscle" RELATED [Wikipedia:Rectus_capitis_lateralis_muscle] is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column synonym: "lateral rectus capitis" EXACT [FMA:46316] xref: FMA:46316 ! rectus capitis lateralis disjoint_from: UBERON:0001603 ! lateral rectus xref: SCTID:244841001 ! Entire rectus capitis lateralis subset: organ_slim synonym: "musculus rectus capitis lateralis" RELATED LATIN [Wikipedia:Rectus_capitis_lateralis_muscle] relationship: has_muscle_origin UBERON:0001077 {source="dbpedia", notes="upper surface of the transverse process of the atlas"} ! transverse process of vertebra relationship: has_muscle_origin UBERON:0001092 {source="dbpedia", notes="upper surface of the transverse process of the atlas"} ! cervical vertebra 1 xref: http://upload.wikimedia.org/wikipedia/commons/b/b7/Rectus_capitis_lateralis_muscle.PNG [Term] id: UBERON:0008453 name: rectus capitis anterior def: "The rectus capitis anterior (rectus capitis anticus minor) is a short, flat muscle, situated immediately behind the upper part of the Longus capitis. It arises from the anterior surface of the lateral mass of the atlas, and from the root of its transverse process, and passing obliquely upward and medialward, is inserted into the inferior surface of the basilar part of the occipital bone immediately in front of the foramen magnum." [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "anterior rectus capitis muscle" RELATED [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "anterior vertebral muscle" RELATED [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "recti capitis anteriores" RELATED [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "rectus capitis" RELATED [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "rectus capitis anterior" RELATED [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "rectus capitus anterior" RELATED [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "rectus capitus anterior muscle" RELATED [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "rectus capitis anterior muscle" EXACT [Wikipedia:Rectus_capitis_anterior_muscle] synonym: "anterior rectus capitis" EXACT [FMA:46312] is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column xref: FMA:46312 ! rectus capitis anterior xref: SCTID:244838005 ! Entire anterior rectus capitis muscle relationship: has_muscle_insertion UBERON:0001676 {source="dbpedia"} ! occipital bone synonym: "musculus rectus capitis anterior" RELATED LATIN [Wikipedia:Rectus_capitis_anterior_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/6/6f/Rectus_capitis_anterior_muscle.PNG [Term] id: UBERON:0008454 name: rectus capitis posterior major def: "The Rectus capitis posterior major (Rectus capitis posticus major) arises by a pointed tendon from the spinous process of the axis, and, becoming broader as it ascends, is inserted into the lateral part of the inferior nuchal line of the occipital bone and the surface of the bone immediately below the line. As the muscles of the two sides pass upward and lateralward, they leave between them a triangular space, in which the Recti capitis posteriores minores are seen. Its main actions are to extend and rotate the atlanto-occipital joint." [Wikipedia:Rectus_capitis_posterior_major_muscle] synonym: "recti capitis posteriores major" RELATED [Wikipedia:Rectus_capitis_posterior_major_muscle] synonym: "rectus capitis posterior major" RELATED [Wikipedia:Rectus_capitis_posterior_major_muscle] synonym: "rectus capitus posterior major" RELATED [Wikipedia:Rectus_capitis_posterior_major_muscle] synonym: "rectus capitus posterior major muscle" RELATED [Wikipedia:Rectus_capitis_posterior_major_muscle] synonym: "rectus capitis posterior major muscle" EXACT [Wikipedia:Rectus_capitis_posterior_major_muscle] synonym: "rectus posterior major" RELATED [Wikipedia:Rectus_capitis_posterior_major_muscle] synonym: "greater posterior rectus capitis" EXACT [FMA:32525] is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column xref: FMA:32525 ! rectus capitis posterior major xref: SCTID:245994002 ! Entire rectus capitis posterior major synonym: "musculus rectus capitis posterior major" RELATED LATIN [Wikipedia:Rectus_capitis_posterior_major_muscle] relationship: has_muscle_insertion UBERON:0001676 {source="dbpedia", notes="Inferior nucheal line of the occipital bone"} ! occipital bone relationship: innervated_by UBERON:0006839 {source="dbpedia", notes="Dorsal ramus of C1"} ! posterior ramus of spinal nerve relationship: has_muscle_origin UBERON:0001093 {source="dbpedia", notes="Spinous process of the axis"} ! cervical vertebra 2 xref: http://upload.wikimedia.org/wikipedia/commons/d/dd/Rectus_capitis_posterior_major_muscle.PNG [Term] id: UBERON:0008455 name: rectus capitis posterior minor def: "The Rectus capitis posterior minor (Rectus capitis posticus minor) arises by a narrow pointed tendon from the tubercle on the posterior arch of the atlas, and, widening as it ascends, is inserted into the medial part of the inferior nuchal line of the occipital bone and the surface between it and the foramen magnum, and also takes some attachment to the spinal dura. The synergists are the rectus capitus posterior major and Obliquus capitis. Connective tissue bridges were noted at the atlanto-occipital junction between the rectus capitis posterior minor muscle and the dorsal spinal dura. The perpendicular arrangement of these fibers appears to restrict dural movement toward the spinal cord. The ligamentum nuchae was found to be continuous with the posterior cervical spinal dura and the lateral portion of the occipital bone. Anatomic structures innervated by cervical nerves C1-C3 have the potential to cause headache pain. Included are the joint complexes of the upper 3 cervical segments, the dura mater, and spinal cord. The dura-muscular, dura-ligamentous connections in the upper cervical spine and occipital areas may provide anatomic and physiologic answers to the cause of the cervicogenic headache. This proposal would further explain manipulation's efficacy in the treatment of cervicogenic headache ." [Wikipedia:Rectus_capitis_posterior_minor_muscle] synonym: "recti capitis posteriores minores" RELATED [Wikipedia:Rectus_capitis_posterior_minor_muscle] synonym: "rectus capitis posterior minor" RELATED [Wikipedia:Rectus_capitis_posterior_minor_muscle] synonym: "rectus capitus posterior minor" RELATED [Wikipedia:Rectus_capitis_posterior_minor_muscle] synonym: "rectus capitus posterior minor muscle" RELATED [Wikipedia:Rectus_capitis_posterior_minor_muscle] synonym: "rectus capitis posterior minor muscle" EXACT [Wikipedia:Rectus_capitis_posterior_minor_muscle] synonym: "rectus posterior minor" RELATED [Wikipedia:Rectus_capitis_posterior_minor_muscle] synonym: "lesser posterior rectus capitis" EXACT [FMA:32526] is_a: UBERON:0004518 {source="FMA"} ! muscle of vertebral column xref: FMA:32526 ! rectus capitis posterior minor xref: SCTID:245995001 ! Entire rectus capitis posterior minor synonym: "musculus rectus capitis posterior minor" RELATED LATIN [Wikipedia:Rectus_capitis_posterior_minor_muscle] relationship: has_muscle_insertion UBERON:0001676 {source="dbpedia", notes="the medial part of the inferior nuchal line of the occipital bone and the surface between it and the foramen magnum"} ! occipital bone relationship: has_muscle_origin UBERON:0008437 {source="dbpedia", notes="the tubercle on the posterior arch of the atlas"} ! posterior arch of atlas xref: http://upload.wikimedia.org/wikipedia/commons/e/ed/Rectus_capitis_posterior_minor.png [Term] id: UBERON:0003251 name: temporal part of head comment: Editor notes: see UBERONREF:0000007 'temporal region' is_a: UBERON:0001444 {source="FMA"} ! subdivision of head synonym: "temporal region" RELATED [FMA:63867] synonym: "temporal region of head" RELATED [FMA:63867] xref: FMA:63867 ! temporal part of head xref: SCTID:362620003 ! Entire temporal region [Term] id: UBERON:0003252 name: rib cage def: "Subdivision of skeletal system that consists of all ribs in an organism connected via the sternum." [UBERON:cjm, Wikipedia:Rib_cage] is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: part_of UBERON:0000915 {source="FMA", notes="check other species"} ! thorax relationship: part_of UBERON:0002090 {source="TAO"} ! postcranial axial skeleton relationship: never_in_taxon NCBITaxon:7778 {source="Wikipedia"} ! Elasmobranchii synonym: "thoracic cage" EXACT [FMA:7480] synonym: "cavea thoracis" EXACT LATIN [FMA:TA, FMA:7480] synonym: "rib series" EXACT [TAO:0002100] xref: FMA:7480 ! rib cage xref: galen:RibCage xref: SCTID:361741004 ! Entire thoracic cage xref: TAO:0002100 ! rib series synonym: "cavea thoracis" RELATED LATIN [Wikipedia:Human_rib_cage] xref: http://upload.wikimedia.org/wikipedia/commons/8/88/Gray112.png property_value: external_definition "Anatomical cluster that consists of more than one rib in an individual.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002100", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0003369 name: fossa ovalis of heart def: "Found in the right atrium of the heart, the fossa ovalis is an embryonic remnant of the foramen ovale, which normally closes shortly after birth. In a heart specimen of a neonate, the fossa ovalis is translucent, but later in life the membrane thickens." [Wikipedia:Fossa_ovalis_(heart)] is_a: UBERON:0006984 {source="FMA"} ! anatomical surface relationship: part_of UBERON:0002078 ! right atrium relationship: develops_from UBERON:0004754 {source="Wikipedia"} ! foramen ovale of heart synonym: "oval fossa" EXACT [FMA:9246] synonym: "fossa ovalis" EXACT [FMA:9246] xref: FMA:9246 ! fossa ovalis xref: SCTID:277719009 ! Entire fossa ovalis of heart [Term] id: UBERON:0008446 name: flexor pollicis longus muscle def: "A muscle in the forearm and hand that flexes the thumb. It lies in the same plane as the flexor digitorum profundus. This muscle is unique to humans, being 'either rudimentary or absent' in other primates." [Wikipedia:Flexor_pollicis_longus_muscle] comment: Taxon notes: Modern humans are unique among hominids in having a flexor pollicis longus (FPL) muscle belly that is separate from that of the flexor digitorum profundus (FDP). While the FPL is not a separate muscle belly in extant great apes, a distinct tendon from the FDP belly might be present. In some individuals this tendon tend to act more like a ligament which restricts extension of the interphalangeal joint of the thumb. In orangutans there is a tendon similar in insertion and function to the FPL in humans, but which has an intrinsic origin on the oblique head of the adductor pollicis[WP] synonym: "musculus flexor pollicis longus" RELATED [Wikipedia:Flexor_pollicis_longus_muscle] synonym: "flexor pollicis muscle" RELATED [Wikipedia:Flexor_pollicis_longus_muscle] synonym: "flexor pollicis" RELATED [Wikipedia:Flexor_pollicis_longus_muscle] synonym: "flexor pollicis longus" RELATED [Wikipedia:Flexor_pollicis_longus_muscle] is_a: UBERON:0004254 {source="Wikipedia"} ! forelimb zeugopod muscle relationship: only_in_taxon NCBITaxon:9606 {source="Wikipedia"} ! Homo sapiens xref: SCTID:361818001 ! Entire flexor pollicis longus muscle xref: FMA:38481 ! Flexor pollicis longus relationship: has_muscle_antagonist UBERON:0003234 {source="dbpedia"} ! extensor pollicis longus synonym: "musculus flexor pollicis longus" RELATED LATIN [Wikipedia:Flexor_pollicis_longus_muscle] relationship: has_muscle_insertion UBERON:0004444 {source="dbpedia", notes="The base of the distal phalanx of the thumb"} ! proximal epiphysis of distal phalanx of manual digit 1 relationship: has_muscle_origin UBERON:0001423 {source="dbpedia", notes="The middle 2/4 of the volar surface of the radius and the adjacent interosseus membrane."} ! radius bone xref: http://upload.wikimedia.org/wikipedia/commons/7/72/FPL.png [Term] id: UBERON:0011012 name: flexor pollicis brevis muscle def: "The flexor pollicis brevis is a muscle in the hand that flexes the thumb. It is one of three thenar muscles. It has both a superficial part and a deep part." [Wikipedia:Flexor_pollicis_brevis_muscle] xref: FMA:37378 ! flexor pollicis brevis synonym: "flexor pollicis brevis" EXACT [FMA:37378] is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0002398 ! manus xref: SCTID:181646006 ! Entire flexor pollicis brevis relationship: has_muscle_insertion UBERON:0001463 {source="dbpedia"} ! manual digit 1 relationship: has_muscle_insertion UBERON:0004302 {source="dbpedia"} ! proximal phalanx synonym: "musculus flexor pollicis brevis" RELATED LATIN [Wikipedia:Flexor_pollicis_brevis_muscle] relationship: has_muscle_antagonist UBERON:0003234 {source="dbpedia", notes="Extensor pollicis longus and brevis"} ! extensor pollicis longus xref: http://upload.wikimedia.org/wikipedia/commons/c/ca/Musculusflexorpollicisbrevis.png [Term] id: UBERON:0001488 ! ankle joint name: ankle joint def: "A joint that connects the hindlimb autopod and zeugopod skeletons." [MESH:A02.835.583.378.062, Wikipedia:Ankle, UBERON:cjm] comment: Taxon notes: todo - accurately represent different types of ankle joint subset: uberon_slim synonym: "hock" NARROW [Wikipedia:Hock_(anatomy)] synonym: "hock joint" NARROW [Wikipedia:Hock_(anatomy)] synonym: "gambrel" NARROW [Wikipedia:Hock_(anatomy)] synonym: "talotibial joint" NARROW [Wikipedia:Ankle] synonym: "talocrural articulation" RELATED [Wikipedia:Ankle] synonym: "talocrural joint" RELATED [Wikipedia:Ankle] xref: FMA:35195 ! Ankle joint xref: GAID:257 ! ankle joint xref: galen:AnkleJoint xref: MA:0000463 ! ankle joint xref: ncithesaurus:Ankle_Joint ! Ankle Joint xref: EFO:0001409 ! ankle (also: UBERON:0004454 'tarsal region') xref: OpenCyc:Mx4rvwiy35wpEbGdrcN5Y29ycA ! ankle joint xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bf/Ankle_en.svg/200px-Ankle_en.svg.png xref: BTO:0004706 ! ankle joint xref: MESH:A02.835.583.378.062 ! ankle joint is_a: UBERON:0002217 ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0010720 ! hindlimb zeugopod skeleton intersection_of: connects UBERON:0001445 ! skeleton of pes relationship: part_of UBERON:0002387 ! pes relationship: connects UBERON:0000979 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! tibia relationship: connects UBERON:0001446 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! fibula xref: SCTID:182212002 ! Entire ankle joint xref: UMLS:C0003087 [Term] id: UBERON:0011969 name: mesotarsal joint def: "An ankle joint that passes between the proximal and distal tarsals." [http://palaeos.com/vertebrates/glossary/glossaryM.html] comment: Calcaneus and astragalus are interlocked, line of flexion is distal to them[Kardong] is_a: UBERON:0001488 ! ankle joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0010721 ! distal tarsal bone intersection_of: connects UBERON:0011679 ! proximal tarsal bone relationship: part_of UBERON:0004454 ! tarsal region [Term] id: UBERON:0012076 name: tibiotalar joint comment: AO notes - see also FMA:44063 ! tibiotalar part of medial ligament of ankle joint synonym: "ankle joint" BROAD [Wikipedia:Ankle] synonym: "talotibial joint" NARROW [Wikipedia:Ankle] synonym: "tibioastragalar joint" NARROW [Wikipedia:Ankle] is_a: UBERON:0001488 ! ankle joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0002395 ! talus xref: SCTID:361864006 ! Entire talotibial joint def: "A skeletal joint that connects a tibia and connects a talus." [OBOL:automatic] [Term] id: UBERON:0011980 name: intratarsal joint def: "an ankle joint that passes between the astragalus and calcaneum." [http://palaeos.com/vertebrates/glossary/glossaryCr.html#Crurotarsal%20joint] comment: line of flexion between calcaneus and astragalus synonym: "crurotarsal joint" EXACT [ISBN10:0073040584] is_a: UBERON:0001488 ! ankle joint [Term] id: UBERON:0011970 name: talofibular ligament synonym: "talo-fibular ligament" EXACT [] synonym: "ligamentum talofibulare" EXACT [] xref: FMA:44080 ! talofibular ligament xref: SCTID:244649001 ! Talofibular ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0001446 ! fibula intersection_of: connects UBERON:0002395 ! talus relationship: part_of UBERON:0001488 ! ankle joint xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bf/Ankle_en.svg/500px-Ankle_en.svg.png def: "A skeletal ligament that connects a fibula and connects a talus." [OBOL:automatic] [Term] id: UBERON:0011971 name: calcaneofibular ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0001446 ! fibula intersection_of: connects UBERON:0001450 ! calcaneus relationship: part_of UBERON:0001488 ! ankle joint xref: FMA:44089 ! calcaneofibular ligament xref: SCTID:244650001 ! Entire calcaneofibular ligament xref: http://upload.wikimedia.org/wikipedia/commons/thumb/b/bf/Ankle_en.svg/500px-Ankle_en.svg.png def: "A skeletal ligament that connects a fibula and connects a calcaneus." [OBOL:automatic] [Term] id: UBERON:0011972 name: medial ligament of ankle joint synonym: "deltoid collateral ligament of ankle joint" EXACT [FMA:44055] synonym: "deltoid ligament of ankle joint" EXACT [FMA:44055] synonym: "ligamentum collaterale mediale (articulatio talocruralis)" EXACT [FMA:44055] synonym: "ligamentum deltoideum" EXACT [FMA:TA] synonym: "ligamentum deltoideum (articulatio talocruralis)" EXACT [FMA:44055] synonym: "medial collateral ligament of ankle joint" EXACT [FMA:44055] intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0009879 ! tarsal skeleton relationship: part_of UBERON:0001488 ! ankle joint xref: FMA:44055 ! medial ligament of ankle joint xref: SCTID:41159004 ! Entire medial ligament of ankle joint def: "A skeletal ligament that connects a tibia and connects a tarsal skeleton." [OBOL:automatic] [Term] id: UBERON:0003698 name: subtalar joint def: "A joint of the pes that connects the talus and the calcaneus." [UBERON:cjm, Wikipedia:Subtalar_joint] synonym: "subtalar joint" EXACT [FMA:35198] synonym: "talocalcaneal joint" RELATED [GAID:260] synonym: "talocalcaneal articulation" RELATED [Wikipedia:Subtalar_joint] xref: FMA:35198 ! Talocalcaneal joint xref: GAID:260 ! subtalar joint xref: ncithesaurus:Subtalar_Joint ! Subtalar Joint xref: MESH:A02.835.583.378.831.780 ! subtalar joint is_a: UBERON:0008447 {source="MESH"} ! intertarsal articulation intersection_of: UBERON:0002217 ! synovial joint intersection_of: connects UBERON:0001450 ! calcaneus intersection_of: connects UBERON:0002395 ! talus relationship: part_of UBERON:0002387 ! pes synonym: "articulatio subtalaris" EXACT LATIN [FMA:TA, FMA:35198] synonym: "articulatio talocalcanea" EXACT LATIN [FMA:TA, FMA:35198] xref: SCTID:182213007 ! Entire subtalar joint xref: http://upload.wikimedia.org/wikipedia/commons/a/a9/Subtalar_Joint.PNG xref: UMLS:C0038593 [Term] id: UBERON:0008447 name: intertarsal joint def: "Intertarsal articulations are the joints of the tarsus. The specific intertarsal articulations are: Talocalcaneal articulation Talocalcaneonavicular articulation Calcaneocuboid articulation Cuneonavicular articulation Cuboideonavicular articulation Intercuneiform articulation Cuneocuboid articulation" [Wikipedia:Intertarsal_articulations] synonym: "intertarsal" RELATED [Wikipedia:Intertarsal_articulations] synonym: "intertarsal articulation" RELATED [Wikipedia:Intertarsal_articulations] synonym: "tarsal joints" RELATED [Wikipedia:Intertarsal_articulations] synonym: "articulationes intertarsale" RELATED [MESH:A02.835.583.378.831] synonym: "articulationes intertarseae" RELATED [MESH:A02.835.583.378.831] synonym: "intermetatarsal joint" RELATED [MESH:A02.835.583.378.831] synonym: "intertarsal joint" RELATED [MESH:A02.835.583.378.831] synonym: "tarsal joint" RELATED [MESH:A02.835.583.378.831] synonym: "articulationes intertarsales" RELATED LATIN [Wikipedia:Intertarsal_articulations] xref: MESH:A02.835.583.378.831 xref: GAID:259 ! tarsal joint xref: ncithesaurus:Tarsal_Joint ! Tarsal Joint xref: FMA:44281 ! Intertarsal joint xref: SCTID:182221001 ! Entire intertarsal joint xref: SCTID:361283005 ! Entire tarsal joint is_a: UBERON:0002217 {source="FMA"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001447 {cardinality="2"} ! tarsal bone relationship: connects UBERON:0001447 {notes="two adjacent tarsals"} ! tarsal bone relationship: part_of UBERON:0004454 ! tarsal region xref: http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray360.png xref: UMLS:C1527245 [Term] id: UBERON:0011133 name: intermetatarsal joint def: "A joint that connects two adjacent metatarsals" [Wikipedia:Intermetatarsal_articulations] comment: In humans: The base of the first metatarsal is not connected with that of the second by any ligaments; in this respect the great toe resembles the thumb[WP] is_a: UBERON:0002217 {source="FMA"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 {cardinality="2"} ! ! metatarsal bone relationship: connects UBERON:0001448 {notes="two adjacent metatarsals"} ! ! metatarsal bone relationship: part_of UBERON:0000983 ! metatarsus region xref: FMA:35219 ! intermetatarsal joint xref: SCTID:361868009 ! Entire intermetatarsal joint xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray358.png [Term] id: UBERON:0011131 name: intermetacarpal joint def: "Synovial joint between the bases of adjacent metacarpals. Examples: intermetacarpal joint of right second and third metacarpal bones, intermetacarpal joint of right fourth and fifth metacarpal bones." [FMA:35288, Wikipedia:Intermetacarpal_articulations] synonym: "intermetacarpal" RELATED [Wikipedia:Intermetacarpal_articulations] synonym: "intermetacarpal articulation" RELATED [Wikipedia:Intermetacarpal_articulations] is_a: UBERON:0002217 {source="FMA"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 {cardinality="2"} ! metacarpal bone relationship: connects UBERON:0002374 {notes="two adjacent metacarpals"} ! metacarpal bone relationship: part_of UBERON:0004453 ! metacarpus region xref: FMA:35288 ! intermetacarpal joint xref: SCTID:303065007 ! Intermetacarpal joint [Term] id: UBERON:0011132 name: intercarpal joint def: "The intercarpal articulations (articulations of the carpus) can be subdivided into three sets of articulations: Those of the proximal row of carpal bones, those of the distal row of carpal bones, and those of the two rows with each other." [Wikipedia:Intercarpal_articulations] synonym: "intercarpal" RELATED [Wikipedia:Intercarpal_articulations] synonym: "intercarpal articulation" RELATED [Wikipedia:Intercarpal_articulations] synonym: "midcarpal articulation" RELATED [Wikipedia:Intercarpal_articulations] synonym: "carpal joint" EXACT [FMA:35292] is_a: UBERON:0002217 {source="FMA"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001435 {cardinality="2"} ! carpal bone relationship: connects UBERON:0001435 {notes="two adjacent carpals"} ! carpal bone relationship: part_of UBERON:0004452 {source="FMA"} ! carpal region xref: FMA:35292 ! intercarpal joint xref: ncithesaurus:Carpal_Joint ! carpal joint xref: SCTID:182176003 ! Entire intercarpal joint xref: http://upload.wikimedia.org/wikipedia/commons/3/37/Gray336.png xref: UMLS:C1262468 [Term] id: UBERON:0011868 name: midcarpal joint def: "." [Wikipedia:Midcarpal_joint] synonym: "transverse carpal joint" EXACT [FMA:35293] synonym: "articulatio mediocarpalis" EXACT LATIN [Wikipedia:Midcarpal_joint] is_a: UBERON:0011132 ! intercarpal joint relationship: connects UBERON:0001480 ! proximal carpal bone relationship: connects UBERON:0001481 ! distal carpal bone xref: FMA:35293 ! midcarpal joint xref: SCTID:361841009 ! Entire midcarpal joint [Term] id: UBERON:0011869 name: pisiform joint def: "." [Wikipedia:Pisiform_joint] comment: Wikipedia says pisiform and triquetral- todo check pisotriquetral synonym: "articulatio ossis pisiformis" EXACT LATIN [Wikipedia:Pisiform_joint] intersection_of: UBERON:0011132 ! intercarpal joint intersection_of: connects UBERON:0001429 ! pisiform intersection_of: connects UBERON:0002445 ! triquetral xref: FMA:73126 ! pisiform joint [Term] id: UBERON:0011870 name: pisotriquetral joint comment: See notes for pisiform is_a: UBERON:0011132 {source="FMA"} ! intercarpal joint xref: FMA:42318 ! pisotriquetral joint [Term] id: UBERON:0008449 name: trochlear notch def: "The semilunar notch of the ulna (trochlear notch of ulna, greater sigmoid cavity) is a large depression, formed by the olecranon and the coronoid process, and serving for articulation with the trochlea of the humerus. About the middle of either side of this notch is an indentation, which contracts it somewhat, and indicates the junction of the olecranon and the coronoid process. The notch is concave from above downward, and divided into a medial and a lateral portion by a smooth ridge running from the summit of the olecranon to the tip of the coronoid process. The medial portion is the larger, and is slightly concave transversely; the lateral is convex above, slightly concave below." [Wikipedia:Trochlear_notch] synonym: "incisura trochlearis" RELATED [Wikipedia:Trochlear_notch] synonym: "semilunar notch" RELATED [Wikipedia:Trochlear_notch] synonym: "semilunar notch of ulna" EXACT [FMA:23619] is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0006822 ! proximal epiphysis of ulna xref: FMA:23619 ! trochlear notch synonym: "incisura trochlearis ulnae, incisura semilunaris ulnae" RELATED LATIN [Wikipedia:Trochlear_notch] xref: http://upload.wikimedia.org/wikipedia/commons/6/60/Gray212.png [Term] id: UBERON:0008464 name: abductor hallucis muscle def: "The Abductor hallucis lies along the medial border of the pes and covers the origins of the plantar vessels and nerves. It arises from the medial process of the tuberosity of the calcaneus, from the laciniate ligament, from the plantar aponeurosis, and from the intermuscular septum between it and the Flexor digitorum brevis. The fibers end in a tendon, which is inserted, together with the medial tendon of the Flexor hallucis brevis, into the tibial side of the base of the first phalanx of the great toe." [Wikipedia:Abductor_hallucis_muscle] synonym: "abductor hallucis" RELATED [Wikipedia:Abductor_hallucis_muscle] is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0008338 ! plantar part of pes xref: Wikipedia:Abductor_hallucis_muscle ! abductor hallucis muscle xref: FMA:37448 ! abductor hallucis xref: SCTID:181723001 ! Entire abductor hallucis muscle synonym: "musculus abductor hallucis" RELATED LATIN [Wikipedia:Abductor_hallucis_muscle] relationship: has_muscle_origin UBERON:0001450 {source="dbpedia", notes="tuberosity of the calcaneus"} ! calcaneus xref: http://upload.wikimedia.org/wikipedia/commons/b/bf/Abductor_hallucis.png [Term] id: UBERON:0011533 name: abductor pollicis, radioulna-prepollox def: "Originates on the distal radioulna and inserts on the palmar prepollex." [AAO:0010805] synonym: "m. abductor pollicis" RELATED [AAO:0010805] is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0002102 ! forelimb relationship: has_muscle_origin UBERON:0006715 ! radio-ulna relationship: has_muscle_insertion UBERON:0005880 ! prepollex xref: AAO:0010805 ! m. abductor pollicis [Term] id: UBERON:0011534 ! abductor pollicis muscle name: abductor pollicis muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0002102 ! forelimb xref: SCTID:368422008 ! Entire abductor pollicis muscle [Term] id: UBERON:0002962 name: adductor pollicis muscle def: "In human anatomy, the adductor pollicis muscle is a muscle in the manus that functions to adduct the thumb. It has two heads: transverse and oblique. It is a fleshy, flat, triangular, and fan-shaped muscle deep in the thenar compartment beneath the long flexor tendons and the lumbrical muscles at the center of the palm. It overlies the metacarpal bones and the interosseous muscles[WP]." [Wikipedia:Adductor_pollicis_muscle] is_a: UBERON:0011145 ! adductor muscle relationship: part_of UBERON:0002398 ! manus synonym: "adductor pollicis" EXACT [Wikipedia:Adductor_pollicis_muscle] xref: FMA:37380 ! adductor pollicis xref: SCTID:181649004 ! Entire adductor pollicis relationship: has_muscle_antagonist UBERON:0008465 {source="dbpedia"} ! abductor pollicis brevis muscle relationship: has_muscle_antagonist UBERON:0001527 {source="dbpedia"} ! abductor pollicis longus synonym: "musculus adductor pollicis" RELATED LATIN [Wikipedia:Adductor_pollicis_muscle] relationship: has_muscle_insertion UBERON:0004445 {source="dbpedia", notes="medial side of the base of the proximal phalanx of the thumb and the ulnar sesamoid"} ! proximal epiphysis of proximal phalanx of manual digit 1 relationship: has_muscle_insertion UBERON:0007993 {source="dbpedia", notes="medial side of the base of the proximal phalanx of the thumb and the ulnar sesamoid"} ! ulnar sesamoid bone xref: http://upload.wikimedia.org/wikipedia/commons/d/df/Musculusadductorpollicis.png [Term] id: UBERON:0011564 name: adductor pollicis muscle of prepollex def: "Originates from the distal carpal 5-4-3 and inserts on the palmar prepollex." [AAO:0010811] synonym: "m. adductor pollicis" RELATED [AAO:0010811] xref: AAO:0010811 ! m. adductor pollicis is_a: UBERON:0011145 ! adductor muscle relationship: has_muscle_insertion UBERON:0005880 ! prepollex [Term] id: UBERON:0001527 name: abductor pollicis longus def: "The Abductor pollicis longus lies immediately below the Supinator and is sometimes united with it. [WP,unvetted]." [Wikipedia:Abductor_pollicis_longus_muscle] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "abductor pollicis longus muscle" RELATED [Wikipedia:Abductor_pollicis_longus_muscle] xref: FMA:38515 ! Abductor pollicis longus xref: MA:0002266 ! abductor pollicis longus xref: ncithesaurus:Abductor_Pollicis_Longus ! Abductor Pollicis Longus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray1231.png/200px-Gray1231.png is_a: UBERON:0011534 ! abductor pollicis muscle relationship: part_of UBERON:0002102 ! forelimb relationship: has_muscle_origin UBERON:0001424 {source="dbpedia"} ! ulna relationship: has_muscle_antagonist UBERON:0002962 {source="dbpedia"} ! adductor pollicis relationship: has_muscle_insertion UBERON:0003645 ! metacarpal bone of digit 1 synonym: "musculus abductor pollicis longus" RELATED LATIN [Wikipedia:Abductor_pollicis_longus_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/6/66/Gray1231.png xref: SCTID:256671001 ! Entire abductor pollicis longus muscle xref: UMLS:C0224278 [Term] id: UBERON:0008465 name: abductor pollicis brevis muscle def: "The abductor pollicis brevis is a muscle in the manus that functions as an abductor of the thumb." [Wikipedia:Abductor_pollicis_brevis_muscle] synonym: "abductor brevis" RELATED [Wikipedia:Abductor_pollicis_brevis_muscle] synonym: "abductor pollicis brevis" RELATED [Wikipedia:Abductor_pollicis_brevis_muscle] is_a: UBERON:0011534 ! abductor pollicis muscle relationship: part_of UBERON:0002398 ! manus xref: Wikipedia:Abductor_pollicis_brevis_muscle ! abductor pollicis brevis muscle xref: FMA:37373 ! abductor pollicis brevis xref: SCTID:181648007 ! Entire abductor pollicis brevis muscle relationship: has_muscle_antagonist UBERON:0002962 {source="dbpedia"} ! adductor pollicis synonym: "musculus abductor pollicis brevis" RELATED LATIN [Wikipedia:Abductor_pollicis_brevis_muscle] relationship: has_muscle_insertion UBERON:0004445 {source="dbpedia", notes="Radial base of proximal phalanx of thumb and the thumb extensors"} ! proximal epiphysis of proximal phalanx of thumb relationship: has_muscle_origin UBERON:0001427 {source="dbpedia", notes="Transverse carpal ligament the scaphoid and trapezium"} ! scaphoid relationship: has_muscle_origin UBERON:0001430 {source="dbpedia", notes="Transverse carpal ligament the scaphoid and trapezium"} ! distal carpal bone 1 xref: http://upload.wikimedia.org/wikipedia/commons/7/77/Musculusabductorpollicisbrevis.png [Term] id: UBERON:0008488 name: cremaster muscle def: "A thin layer of skeletal muscle that envelops the spermatic cord and testis of most male mammals in a series of loops; it is a continuation of the obliquus internus, arising from the inguinal ligament and inserting into the crest of the pubis and into the sheath of the rectus abdominis; it is innervated by the genital branch of the genitofemoral nerve and functions to draw the testis up toward the superficial inguinal ring in response to cold or to stimulation of the nerve; " [Wikipedia:Cremaster_muscle, MGI:anna, MP:0011833] comment: Usage notes: in females it is represented by only a few muscle loops that envelop the round ligament of the uterus. This class represents the male structure synonym: "cremaster muscle" RELATED [Wikipedia:Cremaster_muscle] synonym: "cremasteric muscle" RELATED [Wikipedia:Cremaster_muscle] is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0003135 {source="EMAPA"} ! male reproductive organ relationship: has_muscle_insertion UBERON:0006650 {source="dbpedia"} ! tunica vaginalis testis relationship: has_muscle_origin UBERON:0006204 {source="dbpedia"} ! inguinal ligament relationship: develops_from UBERON:0012326 {source="PMID:11997885", gci_relation="part_of", gci_filler="NCBITaxon:10114"} ! gubernacular bulb xref: EMAPA:31250 ! cremaster muscle xref: FMA:21531 ! cremasteric muscle synonym: "cremaster" EXACT [FMA:21531] synonym: "muscle of Riolan (cremaster)" EXACT [FMA:21531] synonym: "musculus cremaster" EXACT LATIN [FMA:TA] synonym: "musculus cremaster " EXACT LATIN [FMA:TA] xref: ncithesaurus:Cremaster_Muscle ! Cremaster Muscle xref: SCTID:244948006 ! Entire cremaster muscle synonym: "musculus cremaster" RELATED LATIN [Wikipedia:Cremaster_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/6/67/Gray1143.png xref: UMLS:C0224377 [Term] id: UBERON:0008522 name: nasal muscle is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle synonym: "muscle of nose" EXACT [OBOL:automatic] xref: FMA:73758 ! nasal muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000004 ! olfactory apparatus xref: ncithesaurus:Nasal_Muscle ! Nasal Muscle xref: SCTID:244730009 ! Entire muscle of nose def: "A muscle organ that is part of a olfactory apparatus." [OBOL:automatic] xref: UMLS:C0224219 [Term] id: UBERON:0008529 name: piriformis muscle def: "The piriformis is a muscle in the gluteal region that originates from the anterior (front) part of the sacrum, the part of the spine in the gluteal region, and from the superior margin of the greater sciatic notch (as well as the sacroiliac joint capsule and the sacrotuberous ligament). It exits the pelvis through the greater sciatic foramen to insert on the greater trochanter of the femur. Its tendon often joins with the tendons of the superior gemellus, inferior gemellus, and obturator internus muscles prior to insertion[WP,modified]." [Wikipedia:Piriformis_muscle] synonym: "m.piriformis" EXACT [FMA:19082] synonym: "musculus piriformis" RELATED [Wikipedia:Piriformis_muscle] synonym: "piriform muscle" RELATED [Wikipedia:Piriformis_muscle] synonym: "piriformis muscle" RELATED [Wikipedia:Piriformis_muscle] synonym: "piriformis" EXACT [FMA:19082] is_a: UBERON:0002000 {source="FMA"} ! gluteal muscle relationship: part_of UBERON:0004470 {source="FMA"} ! musculature of pelvic girdle xref: FMA:19082 ! piriformis xref: SCTID:245019009 ! Entire piriformis muscle relationship: has_muscle_insertion UBERON:0002503 {source="dbpedia"} ! greater trochanter relationship: has_muscle_origin UBERON:0003690 {source="dbpedia"} ! sacrum synonym: "musculus piriformis" RELATED LATIN [Wikipedia:Piriformis_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Posterior_Hip_Muscles_1.PNG [Term] id: UBERON:0008537 name: quadratus femoris def: "The quadratus femoris is, as its name implies, a flat, quadrilateral skeletal muscle. Located on the posterior side of the hip joint, it is a strong lateral rotator and adductor of the thigh, but also acts to stabilize the femoral head in the Acetabulum." [Wikipedia:Quadratus_femoris_muscle] synonym: "quadratus femoris muscle" RELATED [Wikipedia:Quadratus_femoris_muscle] is_a: UBERON:0002000 {source="FMA"} ! gluteal muscle relationship: part_of UBERON:0004470 {source="FMA"} ! musculature of pelvic girdle xref: FMA:22321 ! quadratus femoris synonym: "musculus quadratus femoris" RELATED LATIN [Wikipedia:Quadratus_femoris_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/5/55/Posterior_Hip_Muscles_1.PNG xref: SCTID:245020003 ! Entire quadratus femoris muscle [Term] id: UBERON:0008538 name: muscle of posterior compartment of thigh def: "The posterior fascial compartment of the thigh contains the knee flexors and hip extensors. It consists of the following muscles: biceps femoris semitendinosus semimembranosus The muscles here (except for the short head of the biceps femoris) are the hamstrings." [Wikipedia:Posterior_compartment_of_thigh] synonym: "posterior fascial compartment of thigh" RELATED [Wikipedia:Posterior_compartment_of_thigh] synonym: "posterior femoral muscle" EXACT [FMA:22427] synonym: "posterior femoral muscles" RELATED [Wikipedia:Posterior_compartment_of_thigh] is_a: UBERON:0004252 {source="FMA"} ! hindlimb stylopod muscle xref: FMA:22427 ! muscle of posterior compartment of thigh synonym: "compartimentum femoris posterius" RELATED LATIN [Wikipedia:Posterior_compartment_of_thigh] xref: http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray432_color.png [Term] id: UBERON:0008544 name: splenius cervicis def: "The splenius cervicis (splenius colli) arises by a narrow tendinous band from the spinous processes of the third to the sixth thoracic vertebrae; it is inserted, by tendinous fasciculi, into the posterior tubercles of the transverse processes of the upper two or three cervical vertebrae." [Wikipedia:Splenius_cervicis_muscle] synonym: "splenius cervicis muscle" RELATED [Wikipedia:Splenius_cervicis_muscle] is_a: UBERON:0002252 {source="FMA"} ! splenius xref: FMA:22681 ! splenius cervicis synonym: "musculus splenius cervicis" RELATED LATIN [Wikipedia:Splenius_cervicis_muscle] relationship: has_muscle_insertion UBERON:0001077 {source="dbpedia", notes="transverse processes of C1-C3"} ! transverse process of vertebra relationship: innervated_by UBERON:0000962 {source="dbpedia", notes="Posterior rami of the lower Cervical spinal nerves"} ! cervical nerve xref: http://upload.wikimedia.org/wikipedia/commons/2/26/Musculus_splenius_cervicis.PNG [Term] id: UBERON:0005493 ! hyoid muscle name: hyoid muscle def: "One of a group of muscles used in mastication and swallowing. These muscles are attached to the hyoid bone, which is suspended in the neck and forms the base of the tongue and larynx. In humans, the muscles are divided into suprahyoid (superior) or infrahyoid (inferior) groups relative to the bone[WP, generalized]." [http://www.answers.com/topic/hyoid-muscles] comment: Editor notes: PMID:19531159 states that facial muscles are hyoid muscles subset: vertebrate_core subset: grouping_class synonym: "hyoid muscles" EXACT [ZFA:0000521] xref: ZFA:0000521 ! hyoid muscle xref: EHDAA2:0000794 ! hyoid muscle xref: EFO:0003536 ! hyoid muscle is_a: UBERON:0002377 {source="ncit"} ! muscle of neck relationship: part_of UBERON:0004467 {source="ZFA"} ! musculature of pharynx relationship: develops_from UBERON:0010348 {source="EHDAA2"} ! hyoid pre-muscle mass relationship: composed_primarily_of UBERON:0002036 {source="EHDAA2"} ! striated muscle tissue relationship: attaches_to UBERON:0005884 ! hyoid arch skeleton xref: ncithesaurus:Hyoid_Muscle ! Hyoid Muscle xref: SCTID:244823009 ! Hyoid muscle xref: TAO:0000521 ! hyoid muscle xref: VHOG:0001494 ! hyoid muscle property_value: homology_notes "Although the zebrafish occupies a rather derived phylogenetic position within actinopterygians and even within teleosts, with respect to the mandibular, hyoid and hypobranchial muscles it seems justified to consider it an appropriate representative of these two groups. Among these muscles, the three with clear homologues in tetrapods and the further three identified in sarcopterygian fish are particularly appropriate for comparisons of results between the actinopterygian zebrafish and the sarcopterygians.[well established][VHOG]" xsd:string {external_class="VHOG:0001494", ontology="VHOG", source="DOI:10.1186/1471-213X-8-24 Diogo R\, Hinits Y\, Hughes SM\, Development of mandibular\, hyoid and hypobranchial muscles in the zebrafish: homologies and evolution of these muscles within bony fishes and tetrapods. BMC Developmental Biology (2008)", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C0448345 [Term] id: UBERON:0010348 name: hyoid pre-muscle mass synonym: "hyoid muscle plate" RELATED [] is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010343 {source="EHDAA2"} ! 2nd arch mesenchyme from head mesenchyme xref: EHDAA2:0000795 ! hyoid pre-muscle mass [Term] id: UBERON:0008571 name: suprahyoid muscle def: "The term suprahyoid refers to the region above (superior to) the hyoid bone in the neck. The suprahyoid muscles include digastric, stylohyoid, geniohyoid, and mylohyoid." [Wikipedia:Suprahyoid_muscles] synonym: "suprahyoid" RELATED [Wikipedia:Suprahyoid_muscles] synonym: "suprahyoidala" RELATED [Wikipedia:Suprahyoid_muscles] is_a: UBERON:0005493 ! hyoid muscle xref: FMA:46290 ! suprahyoid muscle xref: SCTID:244824003 ! Entire suprahyoid muscle synonym: "musculi suprahyoidei" RELATED LATIN [Wikipedia:Suprahyoid_muscles] xref: http://upload.wikimedia.org/wikipedia/commons/5/58/Suprahyoid_muscles.png [Term] id: UBERON:0010930 name: interhyoideus synonym: "interhyoideus muscle" EXACT [] comment: Usage notes: may be obsoleted. Muscle between hyoid arches in fish; Taxon notes: the [mammalian] interhyoideus is homologous with the simple interhyoideus of early stages of amphibia[Edgeworth, 1935]. most extant actinopterygians part of the interhyoideus separates into a distinct muscle during development, the hyohyoideus - http://www.biomedcentral.com/1471-213X/8/24/ xref: AAO:0010649 ! interhyoideus is_a: UBERON:0005493 ! hyoid muscle property_value: external_definition "One of the principal muscles used in swallowing.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010649", date_retrieved="2012-06-20", source="AAO:BMZ"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass hyobranchial muscles (AAO:0000224)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0010649", date_retrieved="2012-06-20"} [Term] id: UBERON:0010932 ! crico-arytenoid muscle name: crico-arytenoid muscle def: "Cricoarytenoid muscles are muscles that connect the cricoid cartilage and arytenoid cartilage. More specifically, it can refer to: Posterior cricoarytenoid muscle Lateral cricoarytenoid muscle" [Wikipedia:Cricoarytenoid_muscle] synonym: "crico-arytenoid" EXACT [Wikipedia:Cricoarytenoid_muscle] synonym: "cricoarytenoid" EXACT [Wikipedia:Cricoarytenoid_muscle] synonym: "cricoarytenoideus" EXACT [] synonym: "cricoarytenoid muscle" EXACT [Wikipedia:Cricoarytenoid_muscle] is_a: UBERON:0006328 {source="FMA"} ! laryngeal intrinsic muscle relationship: part_of UBERON:0001737 {source="FMA"} ! larynx relationship: has_muscle_insertion UBERON:0001740 {source="dbpedia"} ! arytenoid cartilage relationship: innervated_by UBERON:0003716 {source="dbpedia"} ! recurrent laryngeal nerve relationship: has_muscle_origin UBERON:0002375 {source="dbpedia"} ! cricoid cartilage xref: MA:0002283 ! cricoarytenoid xref: ncithesaurus:Cricoarytenoid_Muscle ! cricoarytenoid muscle xref: SCTID:244811003 ! Cricoarytenoid muscle xref: http://upload.wikimedia.org/wikipedia/commons/9/96/Gray959.png xref: UMLS:C0448336 [Term] id: UBERON:0008572 name: posterior crico-arytenoid def: "The posterior cricoarytenoid muscles are extremely small, paired muscles that extend from the posterior cricoid cartilage to the arytenoid cartilages in the larynx. By rotating the arytenoid cartilages laterally, these muscles abduct the vocal cords and thereby open the rima glottidis. Their action opposes the lateral cricoarytenoid muscles. The posterior cricoarytenoid muscles receive innervation from the recurrent laryngeal branch of the vagus nerve (CN X). Paralysis of the posterior cricoarytenoid muscles may lead to asphyxiation as they are the only laryngeal muscles to open the true vocal folds, allowing inspiration and expiration." [Wikipedia:Posterior_cricoarytenoid_muscle] synonym: "cricoaryt%c3%a6noideus posterior" RELATED [Wikipedia:Posterior_cricoarytenoid_muscle] synonym: "cricoarytaenoideus posterior" RELATED [Wikipedia:Posterior_cricoarytenoid_muscle] synonym: "posterior cricoarytenoid muscle" EXACT [Wikipedia:Posterior_cricoarytenoid_muscle] synonym: "posterior cricoarytenoideus" EXACT [FMA:46576] is_a: UBERON:0010932 ! crico-arytenoid muscle xref: FMA:46576 ! posterior crico-arytenoid xref: SCTID:244812005 ! Entire posterior cricoarytenoid muscle relationship: has_muscle_antagonist UBERON:0008573 {source="dbpedia"} ! lateral crico-arytenoid synonym: "musculus cricoarytenoideus posterior" RELATED LATIN [Wikipedia:Posterior_cricoarytenoid_muscle] relationship: has_muscle_insertion UBERON:0001740 {source="dbpedia", notes="muscular process of the arytenoid cartilage"} ! arytenoid cartilage relationship: innervated_by UBERON:0003716 {source="dbpedia", notes="recurrent laryngeal branch of the vagus"} ! recurrent laryngeal nerve relationship: has_muscle_origin UBERON:0002375 {source="dbpedia", notes="posterior part of the cricoid"} ! cricoid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/9/9d/Musculuscricoarytenoideusposterior.png synonym: "posterior cricoarytenoid" EXACT [FMA:46576] [Term] id: UBERON:0008573 name: lateral crico-arytenoid def: "The lateral cricoarytenoid (also anterior cricoarytenoid) muscles extend from the lateral cricoid cartilage to the ipsilateral arytenoid cartilage. By rotating the arytenoid cartilages medially, these muscles adduct the vocal cords and thereby close the rima glottidis, protecting the airway. (Their action is antagonistic to that of the posterior cricoarytenoid muscles. ) The lateral cricoarytenoid muscles receive innervation from the recurrent laryngeal branch of the vagus nerve (CN X)." [Wikipedia:Lateral_cricoarytenoid_muscle] synonym: "cricoaryt%c3%a6noideus lateralis" RELATED [Wikipedia:Lateral_cricoarytenoid_muscle] synonym: "cricoaryt%c3%a6noideus lateralis muscle" RELATED [Wikipedia:Lateral_cricoarytenoid_muscle] synonym: "cricoarytaenoideus lateralis" RELATED [Wikipedia:Lateral_cricoarytenoid_muscle] synonym: "cricoarytaenoideus lateralis muscle" RELATED [Wikipedia:Lateral_cricoarytenoid_muscle] synonym: "lateral cricoarytenoid muscle" EXACT [Wikipedia:Lateral_cricoarytenoid_muscle] synonym: "lateral cricoarytenoideus" EXACT [FMA:46579] is_a: UBERON:0010932 ! crico-arytenoid muscle xref: FMA:46579 ! lateral crico-arytenoid xref: SCTID:244813000 ! Entire lateral cricoarytenoid muscle relationship: has_muscle_antagonist UBERON:0008572 {source="dbpedia"} ! posterior crico-arytenoid synonym: "musculus cricoarytenoideus lateralis" RELATED LATIN [Wikipedia:Lateral_cricoarytenoid_muscle] relationship: has_muscle_insertion UBERON:0001740 {source="dbpedia", notes="muscular process of the arytenoid cartilage"} ! arytenoid cartilage relationship: innervated_by UBERON:0003716 {source="dbpedia", notes="recurrent laryngeal branch of the vagus"} ! recurrent laryngeal nerve relationship: has_muscle_origin UBERON:0002375 {source="dbpedia", notes="lateral part of the arch of the cricoid"} ! cricoid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Musculuscricoarytenoideuslateralis.png synonym: "lateral cricoarytenoid" EXACT [FMA:46579] [Term] id: UBERON:0010958 ! arytenoid muscle name: arytenoid muscle def: "A single muscle, filling up the posterior concave surfaces of the arytenoid cartilages. It arises from the posterior surface and lateral border of one arytenoid cartilage, and is inserted into the corresponding parts of the opposite cartilage. It consists of oblique and transverse parts." [Wikipedia:Arytenoid_muscle] comment: todo - check child relationships synonym: "aryepiglotticus muscle" RELATED [Wikipedia:Arytenoid_muscle] synonym: "arytaenoideus" RELATED [Wikipedia:Arytenoid_muscle] synonym: "arytaenoideus muscle" RELATED [Wikipedia:Arytenoid_muscle] is_a: UBERON:0006328 ! laryngeal intrinsic muscle xref: ncithesaurus:Arytenoid_Muscle ! arytenoid muscle synonym: "Arytænoideus" RELATED LATIN [Wikipedia:Arytenoid_muscle] relationship: has_muscle_insertion UBERON:0001740 {source="dbpedia", notes="Arytenoid cartilage on opposite side"} ! arytenoid cartilage relationship: innervated_by UBERON:0003716 {source="dbpedia", notes="recurrent laryngeal branch of the vagus"} ! recurrent laryngeal nerve relationship: has_muscle_origin UBERON:0001740 {source="dbpedia", notes="Arytenoid cartilage on one side"} ! arytenoid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/5/52/Musculusarytenoideus.png xref: UMLS:C1510945 [Term] id: UBERON:0008574 name: transverse arytenoid def: "The tranverse arytenoid crosses transversely between the two cartilages. It is an unpaired muscle running from one arytenoid to another to pull the arytenoids together." [Wikipedia:Arytenoid_muscle] synonym: "tranverse arytenoid muscle" RELATED [Wikipedia:Transverse_arytenoid] synonym: "arytenoid transversus" RELATED [] is_a: UBERON:0010958 ! arytenoid muscle xref: FMA:46582 ! transverse arytenoid [Term] id: UBERON:0008575 name: oblique arytenoid def: "The oblique arytenoid, the more superficial Arytenoid muscle, forms two fasciculi, which pass from the base of one cartilage to the apex of the opposite one, and therefore cross each other like the limbs of the letter X; a few fibers are continued around the lateral margin of the cartilage, and are prolonged into the aryepiglottic fold; they are sometimes described as a separate muscle, the Aryepiglotticus. The aryepiglottic muscle together with the transverse arytenoid and the thyroarytenoid work as a sphincter and close the larynx as we swallow or cough. Its innervation is by the recurrent laryngeal nerve (from vagus) just like all the intrinsic muscles of the larynx except the cricothyroid muscle." [Wikipedia:Oblique_arytenoid_muscle] synonym: "oblique arytenoid muscle" RELATED [Wikipedia:Oblique_arytenoid] synonym: "arytenoid obliquus" RELATED [] is_a: UBERON:0010958 ! arytenoid muscle xref: FMA:46583 ! oblique arytenoid xref: SCTID:244817004 ! Entire oblique arytenoid muscle [Term] id: UBERON:0008576 ! thyro-arytenoid name: thyro-arytenoid def: "The Thyroarytenoid is a broad, thin, muscle which lies parallel with and lateral to the vocal fold, and supports the wall of the ventricle and its appendix. It functions in fine tonal control of the vocal cords." [Wikipedia:Thyroarytenoid_muscle] synonym: "thyreoaryt%c3%a6noideus" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyreoaryt%c3%a6noideus muscle" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyreoarytaenoideus" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyreoarytaenoideus muscle" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyreoepiglotticus" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyro-arytenoid %26 vocalis" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyro-arytenoid muscle" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyroaryt%c3%a6noideus" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "thyroarytenoid" EXACT [Wikipedia:Thyroarytenoid_muscle] synonym: "thyroarytenoid muscle" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "ventricularis" RELATED [Wikipedia:Thyroarytenoid_muscle] synonym: "ventricularis muscle" RELATED [Wikipedia:Thyroarytenoid_muscle] is_a: UBERON:0006328 {source="FMA"} ! laryngeal intrinsic muscle relationship: part_of UBERON:0001737 {source="FMA"} ! larynx xref: FMA:46588 ! thyro-arytenoid xref: ncithesaurus:Thyroarytenoid_Muscle ! Thyroarytenoid Muscle xref: SCTID:361814004 ! Entire thyroarytenoid muscle synonym: "musculus thyroarytenoideus" RELATED LATIN [Wikipedia:Thyroarytenoid_muscle] relationship: has_muscle_insertion UBERON:0001740 {source="dbpedia", notes="Anterior surface of arytenoid cartilage"} ! arytenoid cartilage relationship: innervated_by UBERON:0003716 {source="dbpedia", notes="recurrent laryngeal branch of the vagus"} ! recurrent laryngeal nerve relationship: has_muscle_origin UBERON:0001738 {source="dbpedia", notes="Inner surface of the thyroid cartilage"} ! thyroid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Musculusthyreoarytenoideus.png xref: UMLS:C0224183 [Term] id: UBERON:0008577 name: vocalis muscle def: "The vocal muscle is the upper portion of the thyroarytenoid muscle which is primarily involved in producing speech." [Wikipedia:Vocal_muscle] synonym: "vocal muscle" EXACT [FMA:46591] synonym: "vocalis" EXACT [] is_a: UBERON:0006328 {source="FMA"} ! laryngeal intrinsic muscle relationship: part_of UBERON:0001737 {source="FMA"} ! larynx relationship: part_of UBERON:0008576 {source="Wikipedia"} ! thyro-arytenoid relationship: has_function_in GO:0071625 ! vocalization behavior xref: SCTID:244820007 ! Entire vocalis muscle xref: FMA:46591 ! vocalis xref: ncithesaurus:Vocalis_Muscle ! Vocalis Muscle synonym: "musculus vocalis" RELATED LATIN [Wikipedia:Vocal_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/6/64/Musculusthyreoarytenoideus.png xref: SCTID:244820007 ! Entire vocalis muscle xref: UMLS:C0224181 [Term] id: UBERON:0008582 name: superior longitudinal muscle of tongue def: "The Longitudinalis linguC& superior (Superior lingualis) is a thin stratum of oblique and longitudinal fibers immediately underlying the mucous membrane on the dorsum of the tongue." [Wikipedia:Superior_longitudinal_muscle_of_tongue] synonym: "longitudinalis lingu%c3%a6 superior" RELATED [Wikipedia:Superior_longitudinal_muscle_of_tongue] synonym: "longitudinalis linguae superior" RELATED [Wikipedia:Superior_longitudinal_muscle_of_tongue] synonym: "musculus longitudinalis superior" EXACT [FMA:46693] synonym: "superior longitudinal muscle" RELATED [Wikipedia:Superior_longitudinal_muscle_of_tongue] is_a: UBERON:0001576 {source="FMA"} ! intrinsic muscle of tongue is_a: UBERON:0012369 ! longitudinal muscle layer xref: FMA:46693 ! superior longitudinal muscle of tongue xref: SCTID:244790006 ! Entire superior longitudinal muscle of tongue relationship: innervated_by UBERON:0001650 {source="dbpedia"} ! hypoglossal nerve synonym: "musculus longitudinalis superior linguae" RELATED LATIN [Wikipedia:Superior_longitudinal_muscle_of_tongue] relationship: has_muscle_insertion UBERON:0001723 {source="dbpedia", notes="edges of the tongue"} ! tongue xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Musculuslongitudinalissuperiorlinguae.png [Term] id: UBERON:0008583 name: transverse muscle of tongue def: "The Transversus linguC& (tansverse lingualis) is a muscle of the tongue. It consists of fibers which arise from the median fibrous septum and pass lateralward to be inserted into the submucous fibrous tissue at the sides of the tongue." [Wikipedia:Transverse_muscle_of_tongue] synonym: "transverse lingual muscle" EXACT [FMA:46695] synonym: "transverse muscle" RELATED [Wikipedia:Transverse_muscle_of_tongue] synonym: "transversus lingu%c3%a6" RELATED [Wikipedia:Transverse_muscle_of_tongue] synonym: "transversus linguae" RELATED [Wikipedia:Transverse_muscle_of_tongue] synonym: "transversus muscle" RELATED [Wikipedia:Transverse_muscle_of_tongue] synonym: "intrinsic tongue muscle transverse component" EXACT [MA:0002328] is_a: UBERON:0001576 {source="FMA"} ! intrinsic muscle of tongue xref: FMA:46695 ! transverse muscle of tongue xref: MA:0002328 ! intrinsic tongue muscle transverse component xref: SCTID:244792003 ! Entire transverse muscle of tongue relationship: innervated_by UBERON:0001650 {source="dbpedia"} ! hypoglossal nerve synonym: "musculus transversus linguae" RELATED LATIN [Wikipedia:Transverse_muscle_of_tongue] relationship: has_muscle_insertion UBERON:0001723 {source="dbpedia", notes="sides of the tongue"} ! tongue xref: http://upload.wikimedia.org/wikipedia/commons/1/14/Musculustransversuslinguae.png xref: ncithesaurus:Intrinsic_Tongue_Muscle_Transverse_Component ! intrinsic tongue muscle transverse component xref: UMLS:C1708561 [Term] id: UBERON:0008584 name: vertical muscle of tongue def: "The Verticalis linguC& (Vertical lingualis) is found only at the borders of the forepart of the tongue. Its fibers extend from the upper to the under surface of the organ." [Wikipedia:Vertical_muscle_of_tongue] synonym: "vertical lingual muscle" EXACT [FMA:46696] synonym: "vertical muscle" RELATED [Wikipedia:Vertical_muscle_of_tongue] synonym: "verticalis lingu%c3%a6" RELATED [Wikipedia:Vertical_muscle_of_tongue] synonym: "verticalis lingu%c3%a6 muscle" RELATED [Wikipedia:Vertical_muscle_of_tongue] synonym: "verticalis linguae" RELATED [Wikipedia:Vertical_muscle_of_tongue] synonym: "verticalis linguae muscle" RELATED [Wikipedia:Vertical_muscle_of_tongue] synonym: "verticalis muscle" RELATED [Wikipedia:Vertical_muscle_of_tongue] is_a: UBERON:0001576 {source="FMA"} ! intrinsic muscle of tongue xref: FMA:46696 ! vertical muscle of tongue xref: SCTID:244793008 ! Entire vertical muscle of tongue relationship: innervated_by UBERON:0001650 {source="dbpedia"} ! hypoglossal nerve synonym: "musculus verticalis linguae" RELATED LATIN [Wikipedia:Vertical_muscle_of_tongue] relationship: has_muscle_insertion UBERON:0007373 {source="dbpedia", notes="Inferior surface borders of tongue"} ! inferior surface of tongue relationship: has_muscle_origin UBERON:0009471 {source="dbpedia", notes="Submucosal fibrous layer of dorsum of tongue"} ! dorsum of tongue xref: http://upload.wikimedia.org/wikipedia/commons/d/d8/Gray1020.png xref: MA:0002329 ! intrinsic tongue muscle vertical component synonym: "intrinsic tongue muscle vertical component" EXACT [MA:0002329] xref: ncithesaurus:Intrinsic_Tongue_Muscle_Vertical_Component ! intrinsic tongue muscle vertical component xref: UMLS:C1708562 [Term] id: UBERON:0008585 name: levator veli palatini def: "The levator veli palatini is the elevator muscle of the velum palatinum in the human body. During swallowing, it contracts, elevating the soft palate to help prevent food from entering the nasopharynx. It is innervated via the pharyngeal plexus, primarily by the vagus nerve (CN X). The levator veli palatini (Levator palati) is a thick, rounded muscle situated lateral to the choanC&. It arises from the under surface of the apex of the petrous part of the temporal bone and from the medial lamina of the cartilage of the auditory tube. After passing above the upper concave margin of the Constrictor pharyngis superior it spreads out in the palatine velum, its fibers extending obliquely downward and medially to the middle line, where they blend with those of the opposite side." [Wikipedia:Levator_veli_palatini] synonym: "levator palati" RELATED [Wikipedia:Levator_veli_palatini] synonym: "levator veli" RELATED [Wikipedia:Levator_veli_palatini] synonym: "levator veli palatini muscle" RELATED [Wikipedia:Levator_veli_palatini] synonym: "levator velum palatini muscle" RELATED [Wikipedia:Levator_veli_palatini] is_a: UBERON:0003682 {source="FMA"} ! palatal muscle xref: FMA:46727 ! levator veli palatini xref: SCTID:244795001 ! Entire levator veli palatini muscle relationship: has_muscle_origin UBERON:0001678 {source="dbpedia"} ! temporal bone synonym: "musculus levator veli palatini" RELATED LATIN [Wikipedia:Levator_veli_palatini] relationship: innervated_by UBERON:0000929 {source="dbpedia", notes="Pharyngeal Branch of Vagus"} ! pharyngeal branch of vagus nerve xref: http://upload.wikimedia.org/wikipedia/commons/a/a5/Musculuslevatorvelipalatini.png property_value: external_definition "The levator veli palatini is part of the soft palate that attaches to the cranial base, pharyngotympanic tube and the soft palate and is innervated by Cranial Nerve X via the pharyngeal plexus.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} relationship: in_lateral_side_of UBERON:0001733 {source="FMA-abduced-lr"} ! soft palate [Term] id: UBERON:0008586 name: tensor veli palatini def: "The tensor veli palatini (tensor palati) is a broad, thin, ribbon-like muscle in the head that tenses the soft palate." [Wikipedia:Tensor_veli_palatini_muscle] synonym: "tensor palati" RELATED [Wikipedia:Tensor_veli_palatini_muscle] synonym: "tensor palati muscle" RELATED [Wikipedia:Tensor_veli_palatini_muscle] synonym: "tensor veli palatini" RELATED [Wikipedia:Tensor_veli_palatini_muscle] synonym: "tensor veli palatini muscle" EXACT [] is_a: UBERON:0003682 {source="FMA"} ! palatal muscle xref: FMA:46730 ! tensor veli palatini xref: SCTID:361815003 ! Entire tensor veli palatini muscle synonym: "musculus tensor veli palatini" RELATED LATIN [Wikipedia:Tensor_veli_palatini_muscle] relationship: innervated_by UBERON:0000375 {source="dbpedia", notes="medial pterygoid of mandibular nerve"} ! mandibular nerve xref: http://upload.wikimedia.org/wikipedia/commons/3/30/Musculustensorvelipalatini.png property_value: external_definition "The tensor veli palatini is a muscle of the soft palate that attaches to the cranial base and pharyngotympanic tube, wraps around the pterygoid hamulus and then attaches to the midline palatal raphe of the soft palate that is innervated by cranial nerve V3.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} relationship: in_lateral_side_of UBERON:0001733 {source="FMA-abduced-lr"} ! soft palate [Term] id: UBERON:0008588 name: procerus def: "The Procerus is a small pyramidal slip of muscle deep to the superior orbital nerve, artery and vein." [Wikipedia:Procerus_muscle] synonym: "depressor glabellae" RELATED [Wikipedia:Procerus_muscle] synonym: "procerus muscle" RELATED [Wikipedia:Procerus_muscle] synonym: "pyramidalis nasi" RELATED [Wikipedia:Procerus_muscle] is_a: UBERON:0008522 {source="FMA"} ! nasal muscle xref: FMA:46769 ! procerus synonym: "musculus procerus, pyramidalis nasi, depressor glabellae" RELATED LATIN [Wikipedia:Procerus_muscle] relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="Temporal Branch of the facial nerve"} ! facial nerve xref: http://upload.wikimedia.org/wikipedia/commons/7/76/Procerus.png xref: SCTID:244731008 ! Entire procerus muscle [Term] id: UBERON:0008589 name: depressor septi nasi def: "The depressor septi (Depressor alE nasi) arises from the incisive fossa of the maxilla. Its fibers ascend to be inserted into the nasal septum and back part of the alar part of nasalis muscle. It lies between the mucous membrane and muscular structure of the lip." [Wikipedia:Depressor_septi_nasi_muscle] synonym: "depressor al%c3%a6 nasi" RELATED [Wikipedia:Depressor_septi_nasi_muscle] synonym: "depressor alae nasi" RELATED [Wikipedia:Depressor_septi_nasi_muscle] synonym: "depressor septi" EXACT [Wikipedia:Depressor_septi_nasi_muscle] synonym: "depressor septi nasi muscle" RELATED [Wikipedia:Depressor_septi_nasi_muscle] is_a: UBERON:0008522 {source="FMA"} ! nasal muscle xref: FMA:46777 ! depressor septi nasi xref: SCTID:244733006 ! Depressor septi synonym: "musculus depressor septi nasi" RELATED LATIN [Wikipedia:Depressor_septi_nasi_muscle] relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="Buccal branch of the facial nerve"} ! facial nerve relationship: has_muscle_origin UBERON:0002397 {source="dbpedia", notes="incisive fossa of the maxilla"} ! maxilla xref: http://upload.wikimedia.org/wikipedia/commons/6/6c/Musculusdepressorseptinasi.PNG [Term] id: UBERON:0008591 name: depressor supercilii def: "The Depressor Supercilii is an eye muscle of the human body. The nature of this muscle is in some dispute. Few printed anatomies include it (Netter, et al. ) and many authorities consider it to be part of the orbicularis oculi muscle . On the other hand, many dermatologists, ophthalmologists and plastic surgeons hold that the depressor supercilli is a distinct muscle and has a definite, individual effect on the movement of the eybrow and skin of the glabella." [Wikipedia:Depressor_supercilii_muscle] synonym: "depressor supercilii muscle" RELATED [Wikipedia:Depressor_supercilii_muscle] is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle xref: FMA:46798 ! depressor supercilii relationship: innervated_by UBERON:0001647 {source="dbpedia"} ! facial nerve synonym: "musculus depressor supercilii" RELATED LATIN [Wikipedia:Depressor_supercilii_muscle] relationship: has_muscle_insertion UBERON:0001697 {source="dbpedia", notes="Medial aspect of bony orbit"} ! orbit xref: http://upload.wikimedia.org/wikipedia/commons/e/e2/Gray379.png xref: SCTID:244728007 ! Entire depressor supercilii muscle [Term] id: UBERON:0008592 name: levator labii superioris alaeque nasi def: "The levator labii superioris alaeque nasi muscle is, translated from Latin, the \"lifter of the upper lip and of the wing of the nose\". It has the longest name of any muscle in an animal." [Wikipedia:Levator_labii_superioris_alaeque_nasi_muscle] synonym: "alaeque" RELATED [Wikipedia:Levator_labii_superioris_alaeque_nasi_muscle] synonym: "elvis muscle" RELATED [Wikipedia:Levator_labii_superioris_alaeque_nasi_muscle] synonym: "levator labii superioris alaeque nasi" RELATED [Wikipedia:Levator_labii_superioris_alaeque_nasi_muscle] synonym: "levator labii superioris alaequae nasi muscle" RELATED [Wikipedia:Levator_labii_superioris_alaeque_nasi_muscle] is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle xref: FMA:46802 ! levator labii superioris alaeque nasi relationship: has_muscle_origin UBERON:0002397 {source="dbpedia"} ! maxilla synonym: "musculus levator labii superioris alaequae nasi" RELATED LATIN [Wikipedia:Levator_labii_superioris_alaeque_nasi_muscle] relationship: has_muscle_insertion UBERON:0005928 {source="dbpedia", notes="nostril and upper lip"} ! external naris relationship: has_muscle_insertion UBERON:0001834 {source="dbpedia", notes="nostril and upper lip"} ! upper lip relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="buccal branch of facial nerve CN VII"} ! facial nerve xref: http://upload.wikimedia.org/wikipedia/commons/1/1c/Musculuslevatorlabiisuperiorisalaequenasi.png [Term] id: UBERON:0010437 ! zygomaticus muscle name: zygomaticus muscle def: "One of: zygomaticus major, zygomaticus minor" [UBERON:cjm] comment: origin: posterior braincase subset: grouping_class is_a: UBERON:0001630 {source="MA"} ! muscle organ relationship: part_of UBERON:0001456 ! face relationship: has_muscle_origin UBERON:0001683 {source="Wikipedia"} ! zygomatic bone relationship: innervated_by UBERON:0001647 {source="Wikipedia"} ! facial nerve xref: MA:0002404 ! zygomaticus xref: ncithesaurus:Zygomaticus ! zygomaticus synonym: "zygomaticus" EXACT [MA:0002404] synonym: "m. zygomaticus" EXACT [] synonym: "m. levator nasii" RELATED [] xref: UMLS:C1710708 [Term] id: UBERON:0008593 name: zygomaticus major muscle def: "The Zygomatic major is a muscle of the human body. It is a muscle of facial expression which draws the angle of the mouth superiorly and posteriorly. Like all muscles of facial expression, the zygomatic major is innervated by the facial nerve (Cranial Nerve VII). The Zygomaticus extends from each zygomatic arch to the corners of the mouth. It raises the corners of the mouth when a person smiles. Dimples may be caused by variations in the structure of this muscle." [Wikipedia:Zygomaticus_major_muscle] synonym: "zygomatic major" RELATED [Wikipedia:Zygomaticus_major_muscle] synonym: "zygomatic major muscle" RELATED [Wikipedia:Zygomaticus_major_muscle] synonym: "zygomatic muscle" RELATED [Wikipedia:Zygomaticus_major_muscle] synonym: "zygomaticcus major" RELATED [Wikipedia:Zygomaticus_major_muscle] synonym: "zygomaticus major" RELATED [Wikipedia:Zygomaticus_major_muscle] is_a: UBERON:0010437 ! zygomaticus muscle xref: FMA:46810 ! zygomaticus major xref: ncithesaurus:Zygomaticus_Major ! Zygomaticus Major xref: SCTID:244739005 ! Zygomatic muscle synonym: "musculus zygomaticus major" RELATED LATIN [Wikipedia:Zygomaticus_major_muscle] relationship: has_muscle_origin UBERON:0001683 {source="Wikipedia"} ! zygomatic bone relationship: has_muscle_insertion UBERON:0011386 ! facial modiolus relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="zygomatic branch of facial nerve"} ! facial nerve xref: http://upload.wikimedia.org/wikipedia/commons/7/7e/Zygomaticus.png xref: SCTID:244740007 ! Entire zygomaticus major muscle xref: UMLS:C0224115 [Term] id: UBERON:0008594 name: zygomaticus minor muscle def: "The zygomaticus minor is a muscle of facial expression. It originates from malar bone and continues with orbicularis oculi on the lateral face of the Levator labii superioris and then inserts into the outer part of the upper lip. Do not confuse this with the Zygomaticus major, which insets into the angle of the mouth. It draws the upper lip backward, upward, and outward (used in making sad facial expressions). </gallery> Like all muscles of facial expression, it is innervated by the facial nerve (CN VII)." [Wikipedia:Zygomaticus_minor_muscle] synonym: "zygomaticus minor" RELATED [Wikipedia:Zygomaticus_minor_muscle] is_a: UBERON:0010437 ! zygomaticus muscle xref: FMA:46811 ! zygomaticus minor xref: ncithesaurus:Zygomaticus_Minor ! Zygomaticus Minor relationship: innervated_by UBERON:0001647 {source="dbpedia"} ! facial nerve relationship: has_muscle_origin UBERON:0001683 {source="dbpedia"} ! zygomatic bone relationship: has_muscle_insertion UBERON:0001458 {source="dbpedia", notes="skin of the upper lip"} ! skin of lip relationship: has_muscle_insertion UBERON:0001834 {source="dbpedia", notes="skin of the upper lip"} ! upper lip xref: http://upload.wikimedia.org/wikipedia/commons/4/46/Musculuszygomaticusminor.png xref: SCTID:244741006 ! Entire zygomaticus minor muscle xref: UMLS:C0224116 [Term] id: UBERON:0008595 name: levator anguli oris def: "The levator anguli oris (caninus) is a facial muscle of the mouth arising from the canine fossa, immediately below the infraorbital foramen. Its fibers are inserted into the angle of the mouth, intermingling with those of the Zygomaticus, Triangularis, and Orbicularis oris." [Wikipedia:Levator_anguli_oris_muscle] synonym: "caninus" RELATED [Wikipedia:Levator_anguli_oris] synonym: "caninus muscle" RELATED [Wikipedia:Levator_anguli_oris] synonym: "levator anguli oris" RELATED [Wikipedia:Levator_anguli_oris] synonym: "levator anguli oris muscle" EXACT [Wikipedia:Levator_anguli_oris] synonym: "musculus levator anguli oris" RELATED [Wikipedia:Levator_anguli_oris] is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle xref: FMA:46822 ! levator anguli oris relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="buccal branches"} ! facial nerve relationship: has_muscle_origin UBERON:0002397 {source="dbpedia"} ! maxilla relationship: has_muscle_insertion UBERON:0011386 ! facial modiolus xref: SCTID:141501002 ! Entire levator anguli oris muscle [Term] id: UBERON:0008596 name: mentalis def: "The Mentalis is a paired central muscle of the lower lip, situated at the tip of the chin. It raises and pushes up the lower lip, causing wrinkling of the chin, as in doubt or displeasure. It is ometimes referred to as the \"pouting muscle. \" Its fibers arise from the incisive fossa of the mandible, then course vertically downward to insert in the skin of the chin. A movement disorder of the mentalis muscle is Geniospasm which is a benign but socially excluding genetic disorder." [Wikipedia:Mentalis] synonym: "musculus mentalis" EXACT LATIN [Wikipedia:Mentalis] synonym: "mentalis muscle" EXACT [Wikipedia:Mentalis] is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle xref: FMA:46825 ! mentalis xref: SCTID:244744003 ! Entire mentalis muscle relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="mandibular branch"} ! facial nerve relationship: has_muscle_insertion UBERON:0008199 {source="dbpedia"} ! chin relationship: has_muscle_origin UBERON:0001684 {source="dbpedia"} ! mandible xref: http://upload.wikimedia.org/wikipedia/commons/3/37/Mentalis.png relationship: in_lateral_side_of UBERON:0008199 {source="FMA-abduced-lr"} ! chin [Term] id: UBERON:0008597 name: depressor anguli oris muscle def: "The Depressor anguli oris (Triangularis) arises from the oblique line of the mandible, whence its fibers converge, to be inserted, by a narrow fasciculus, into the angle of the mouth." [Wikipedia:Depressor_anguli_oris_muscle] synonym: "depressor anguli oris" RELATED [Wikipedia:Depressor_anguli_oris_muscle] synonym: "triangularis" RELATED [Wikipedia:Depressor_anguli_oris_muscle] synonym: "triangularis muscle" RELATED [Wikipedia:Depressor_anguli_oris_muscle] is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle xref: FMA:46828 ! depressor anguli oris xref: SCTID:361812000 ! Entire depressor anguli oris muscle synonym: "musculus depressor anguli oris" RELATED LATIN [Wikipedia:Depressor_anguli_oris_muscle] relationship: has_muscle_insertion UBERON:0011386 {source="dbpedia", notes="modiolus of mouth"} ! facial modiolus relationship: has_muscle_origin UBERON:0001684 {source="dbpedia", notes="tubercle of mandible"} ! mandible relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="mandibular branch"} ! facial nerve xref: http://upload.wikimedia.org/wikipedia/commons/3/36/Gray381.png [Term] id: UBERON:0011386 ! facial modiolus name: facial modiolus def: "In facial anatomy, the modiolus is a chiasma of facial muscles held together by fibrous tissue, located lateral and slightly superior to each angle of the mouth. It is important in moving the mouth, facial expression and in dentistry. It derives its motor nerve supply from the facial nerve, and its blood supply from labial branches of the facial artery. It is contributed to by the following muscles: orbicularis oris, buccinator, levator anguli oris, depressor anguli oris, zygomaticus major, risorius quadratus labii superioris, quadratus labii inferioris." [Wikipedia:Modiolus_%28face%29] is_a: UBERON:0002385 ! muscle tissue relationship: part_of UBERON:0001567 {source="FMA"} ! cheek xref: FMA:46837 ! facial modiolus disjoint_from: UBERON:0006723 ! cochlear modiolus [Term] id: UBERON:0008598 name: risorius muscle def: "The risorius arises in the fascia over the parotid gland and, passing horizontally forward, superficial to the platysma, inserts onto the skin at the angle of the mouth. It is a narrow bundle of fibers, broadest at its origin, but varies much in its size and form." [Wikipedia:Risorius] synonym: "risorius" EXACT [Wikipedia:Risorius] is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle xref: FMA:46838 ! risorius xref: SCTID:244755003 ! Entire risorius muscle relationship: has_muscle_origin UBERON:0001831 {source="dbpedia"} ! parotid gland relationship: has_muscle_insertion UBERON:0011386 ! facial modiolus relationship: innervated_by UBERON:0001647 {source="dbpedia", notes="buccal branch"} ! facial nerve synonym: "musculus risorius" RELATED LATIN [Wikipedia:Risorius] xref: http://upload.wikimedia.org/wikipedia/commons/a/af/Musculusrisorius.png [Term] id: UBERON:0011385 name: parotidoauricular muscle def: "Is one of the numerus muscles of the external ear and is of importance since it is encountered in the operation for drainage of infections of the external ear of the dog. As its name suggests, it arises from the fascia over the parotid gland and approaches the auricle from the ventrolateral direction. This muscle is supplied by the facial nerve.The muscles of the external ear with their scattered origins and precisely located insertions provide for displacement and rotation of the ear in all directions. These muscles also have a collective function in communication both within and between species." [MURDOCH:1519] is_a: UBERON:0001583 ! extrinsic auricular muscle relationship: has_muscle_origin UBERON:0001831 ! parotid gland relationship: has_muscle_insertion UBERON:0001757 ! pinna xref: MA:0002352 ! parotidoauricular synonym: "parotidoauricular" EXACT [MA:0002352] synonym: "parotidoauricularis" EXACT [] xref: ncithesaurus:Parotidoauricular ! parotidoauricular xref: UMLS:C1709470 [Term] id: UBERON:0008603 name: helicis major def: "The Helicis major is a narrow vertical band situated upon the anterior margin of the helix. It arises below, from the spina helicis, and is inserted into the anterior border of the helix, just where it is about to curve backward." [Wikipedia:Helicis_major] is_a: UBERON:0001596 {source="FMA"} ! intrinsic auricular muscle xref: FMA:48968 ! helicis major synonym: "musculus helicis major" EXACT LATIN [Wikipedia:Helicis_major] synonym: "helicis major muscle" RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray906.png xref: SCTID:244764008 ! Entire helicis major muscle [Term] id: UBERON:0008604 name: helicis minor def: "The Helicis minor is an oblique fasciculus, covering the crus helicis." [Wikipedia:Helicis_minor] is_a: UBERON:0001596 {source="FMA"} ! intrinsic auricular muscle xref: FMA:48971 ! helicis minor synonym: "musculus helicis minor" RELATED LATIN [Wikipedia:Helicis_minor] synonym: "helicis minor muscle" RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray906.png xref: SCTID:244765009 ! Entire helicis minor muscle [Term] id: UBERON:0008605 name: tragicus muscle def: "The Tragicus is a short, flattened vertical band on the lateral surface of the tragus." [Wikipedia:Tragicus] is_a: UBERON:0001596 {source="FMA"} ! intrinsic auricular muscle xref: FMA:48974 ! tragicus xref: SCTID:244766005 ! Entire tragicus muscle synonym: "tragicus" EXACT [FMA:48974] synonym: "musculus tragicus" RELATED LATIN [Wikipedia:Tragicus] synonym: "tragicus muscle" RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray906.png [Term] id: UBERON:0008606 name: antitragicus muscle def: "The Antitragicus arises from the outer part of the antitragus, and is inserted into the cauda helicis and antihelix." [Wikipedia:Antitragicus] is_a: UBERON:0001596 {source="FMA"} ! intrinsic auricular muscle xref: FMA:48980 ! antitragicus synonym: "musculus antitragicus" RELATED LATIN [Wikipedia:Antitragicus] synonym: "antitragicus muscle" RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/5/58/Musculusantitragicus.png xref: SCTID:63899000 ! Entire antitragicus muscle synonym: "antitragicus" EXACT [FMA:48980] [Term] id: UBERON:0008607 name: transverse muscle of auricle def: "The transverse muscle of auricle is placed on the cranial surface of the pinna. It consists of scattered fibers, partly tendinous and partly muscular, extending from the eminentia conchae to the prominence corresponding with the scapha." [Wikipedia:Transverse_muscle_of_auricle] synonym: "transverse muscle of pinna" EXACT [FMA:48983] synonym: "transversus auriculae" EXACT [Wikipedia:Transverse_muscle_of_auricle] synonym: "transversus auricularis" EXACT [FMA:48983] is_a: UBERON:0001596 {source="FMA"} ! intrinsic auricular muscle xref: FMA:48983 ! transverse muscle of auricle synonym: "musculus transversus auriculae" RELATED LATIN [Wikipedia:Transverse_muscle_of_auricle] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray906.png xref: SCTID:244767001 ! Entire transversus auricularis muscle [Term] id: UBERON:0008608 name: oblique muscle of auricle def: "The oblique muscle of auricle, on the cranial surface, consists of a few fibers extending from the upper and back part of the concha to the convexity immediately above it." [Wikipedia:Oblique_muscle_of_auricle] synonym: "oblique muscle of pinna" EXACT [FMA:48986] synonym: "obliquus auricul%c3%a6" RELATED [Wikipedia:Oblique_muscle_of_auricle] synonym: "obliquus auriculae" EXACT [Wikipedia:Oblique_muscle_of_auricle] synonym: "obliquus auricularis muscle" EXACT [FMA:48986] is_a: UBERON:0001596 {source="FMA"} ! intrinsic auricular muscle xref: FMA:48986 ! oblique muscle of auricle xref: SCTID:244768006 ! Entire obliquus auricularis muscle synonym: "musculus obliquus auriculae" RELATED LATIN [Wikipedia:Oblique_muscle_of_auricle] xref: http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray906.png [Term] id: UBERON:0008609 name: transversus menti muscle def: "The transversus menti, or transverse muscle of the chin, is a facial muscle that is often considered to be the superficial fibers of the depressor anguli oris muscle which cross to the other side of the face." [Wikipedia:Transverse_muscle_of_the_chin] synonym: "transverse menti" EXACT [FMA:49080] synonym: "transversus menti" RELATED [Wikipedia:Transverse_muscle_of_the_chin] is_a: UBERON:0001577 {source="FMA"} ! facial nerve muscle xref: FMA:49080 ! transversus menti relationship: innervated_by UBERON:0001647 {source="dbpedia"} ! facial nerve synonym: "musculus transversus menti" RELATED LATIN [Wikipedia:Transverse_muscle_of_the_chin] xref: http://upload.wikimedia.org/wikipedia/commons/3/36/Gray381.png [Term] id: UBERON:0008611 name: scalene muscle def: "Any of the three pairs of muscles in the lateral neck, namely the scalenus anterior, scalenus medius, and scalenus posterior. They are innervated by the spinal nerves C4-C8[WP]." [Wikipedia:Scalene_muscles] synonym: "lateral cervical muscle" RELATED [Wikipedia:Scalene_muscles] synonym: "lateral cervical muscles" RELATED [Wikipedia:Scalene_muscles] synonym: "lateral vertebral muscle" RELATED [Wikipedia:Scalene_muscles] synonym: "m scalenus" RELATED [Wikipedia:Scalene_muscles] synonym: "scalene muscle" RELATED [Wikipedia:Scalene_muscles] synonym: "scalene muscles" EXACT [Wikipedia:Scalene_muscles] synonym: "scalenes" RELATED [Wikipedia:Scalene_muscles] synonym: "scaleni" RELATED [Wikipedia:Scalene_muscles] synonym: "scaleneus" RELATED [Wikipedia:Scalene_muscles] synonym: "scalenus" RELATED [Wikipedia:Scalene_muscles] synonym: "scalenus muscle" EXACT [FMA:64829] is_a: UBERON:0002377 {source="FMA"} ! muscle of neck xref: FMA:64829 ! scalene muscle xref: ncithesaurus:Scalene_Muscle ! Scalene Muscle xref: SCTID:244843003 ! Scalene muscle relationship: has_muscle_origin UBERON:0002413 {source="dbpedia"} ! cervical vertebra relationship: has_muscle_insertion UBERON:0004601 {source="dbpedia", notes="first and second ribs"} ! rib 1 relationship: has_muscle_insertion UBERON:0004602 {source="dbpedia", notes="first and second ribs"} ! rib 2 xref: http://upload.wikimedia.org/wikipedia/commons/6/6e/Scalenus.png xref: UMLS:C0448350 [Term] id: UBERON:0008612 name: muscle of pelvic diaphragm def: "The pelvic floor or pelvic diaphragm is composed of muscle fibers of the levator ani, the coccygeus, and associated connective tissue which span the area underneath the pelvis. The pelvic diaphragm is a muscular partition formed by the levatores ani and coccygei, with which may be included the parietal pelvic fascia on their upper and lower aspects. The pelvic floor separates the pelvic cavity above from the perineal region below. The right and left levator ani lie almost horizontally in the floor of the pelvis, separated by a narrow gap that transmits the urethra, vagina, and anal canal. The levator ani is usually considered in three parts: pubococcygeus, puborectalis, and iliococcygeus. The pubococcygeus, the main part of the levator, runs backward from the body of the pubis toward the coccyx and may be damaged during parturition. Some fibers are inserted into the prostate, urethra, and vagina. The right and left puborectalis unite behind the anorectal junction to form a muscular sling . Some regard them as a part of the sphincter ani externus. The iliococcygeus, the most posterior part of the levator ani, is often poorly developed. The coccygeus, situated behind the levator ani and frequently tendinous as much as muscular, extends from the ischial spine to the lateral margin of the sacrum and coccyx. The pelvic cavity of the true pelvis has the pelvic floor as its inferior border (and the pelvic brim as its superior border. ) The perineum has the pelvic floor as its superior border. Some sources do not consider \"pelvic floor\" and \"pelvic diaphragm\" to be identical, with the \"diaphragm\" consisting of only the levator ani and coccygeus, while the \"floor\" also includes the perineal membrane and deep perineal pouch. However, other sources include the fascia as part of the diaphragm. In practice, the two terms are often used interchangeably. Inferiorly, the pelvic floor extends into the anal triangle." [Wikipedia:Pelvic_floor] synonym: "diaphragm of the pelvis" RELATED [Wikipedia:Pelvic_floor] synonym: "muscle of pelvic floor" EXACT [FMA:64856] synonym: "pelvic diaphragm" RELATED [Wikipedia:Pelvic_floor] synonym: "pelvic diaphragm muscle" EXACT [FMA:64856] synonym: "pelvic floor muscles" RELATED [Wikipedia:Pelvic_floor] synonym: "pelvic muscles" RELATED [Wikipedia:Pelvic_floor] is_a: UBERON:0001325 {source="FMA"} ! muscle of pelvis xref: FMA:64856 ! muscle of pelvic diaphragm xref: ncithesaurus:Pelvic_Floor_Muscle ! Pelvic Floor Muscle synonym: "diaphragma pelvis" RELATED LATIN [Wikipedia:Pelvic_floor] xref: http://upload.wikimedia.org/wikipedia/commons/6/63/Gray404.png xref: SCTID:367748001 ! Entire pelvic diaphragm xref: UMLS:C0932441 [Term] id: UBERON:0008617 name: innermost intercostal muscle def: "The Innermost intercostal muscle is a layer of intercostal muscle beneath the intercostal nerves and internal intercostal muscles. These are divided into transversus thoracis anteriorly, lateral muscle slips laterally and subcostalis posteriorly." [Wikipedia:Innermost_intercostal_muscle] synonym: "musculus intercostalis intimus" RELATED [Wikipedia:Innermost_intercostal_muscle] is_a: UBERON:0001111 {source="FMA"} ! intercostal muscle xref: FMA:9758 ! innermost intercostal muscle xref: SCTID:368054008 ! Entire innermost intercostal muscle relationship: innervated_by UBERON:0003727 {source="dbpedia"} ! intercostal nerve synonym: "musculus intercostalis intimus" RELATED LATIN [Wikipedia:Innermost_intercostal_muscle] relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="Inferior border of the rib above"} ! rib relationship: has_muscle_origin UBERON:0002228 {source="dbpedia", notes="Upper border of a rib"} ! rib [Term] id: UBERON:0008618 name: subcostal muscle def: "The Subcostales (Infracostales) consist of muscular and aponeurotic fasciculi, which are usually well-developed only in the lower part of the thorax; each originates from the inner surface of one rib, and is inserted into the inner surface of the second or third rib above, near its angle. Their fibers run in the same direction as those of the Intercostales interni." [Wikipedia:Subcostalis_muscle] synonym: "subcostal muscles" RELATED [Wikipedia:Subcostalis_muscle] synonym: "subcostales" RELATED [Wikipedia:Subcostalis_muscle] synonym: "subcostales muscle" RELATED [Wikipedia:Subcostalis_muscle] synonym: "subcostales muscles" RELATED [Wikipedia:Subcostalis_muscle] synonym: "subcostalis" RELATED [Wikipedia:Subcostalis_muscle] is_a: UBERON:0002426 {source="FMA"} ! chest muscle xref: FMA:9759 ! subcostal muscle xref: SCTID:244914005 ! Entire subcostal muscle relationship: innervated_by UBERON:0003727 {source="dbpedia"} ! intercostal nerve synonym: "musculus subcostalis" RELATED LATIN [Wikipedia:Subcostalis_muscle] relationship: has_muscle_insertion UBERON:0002228 {source="dbpedia", notes="inner surface of the second or third rib below near its angle"} ! rib relationship: has_muscle_origin UBERON:0002228 {source="dbpedia", notes="inner surface of one rib"} ! rib [Term] id: UBERON:0008622 name: scalenus anterior def: "The Scalenus anterior (Scalenus anticus), also known as anterior scalene muscle, lies deeply at the side of the neck, behind the Sternocleidomastoideus. It arises from the anterior tubercles of the transverse processes of the third, fourth, fifth, and sixth cervical vertebrC&, and descending, almost vertically, is inserted by a narrow, flat tendon into the scalene tubercle on the inner border of the first rib, and into the ridge on the upper surface of the rib in front of the subclavian groove." [Wikipedia:Scalenus_anterior] synonym: "anterior scalene" EXACT [Wikipedia:Scalenus_anterior] synonym: "scalenus anterior muscle" RELATED [Wikipedia:Scalenus_anterior] synonym: "scalenus anticus" RELATED [Wikipedia:Scalenus_anterior] is_a: UBERON:0008611 {source="FMA"} ! scalene muscle xref: FMA:13385 ! scalenus anterior relationship: has_muscle_insertion UBERON:0004601 {source="dbpedia"} ! rib 1 relationship: has_muscle_origin UBERON:0002413 {source="dbpedia"} ! cervical vertebra synonym: "musculus scalenus anterior" RELATED LATIN [Wikipedia:Scalenus_anterior] xref: http://upload.wikimedia.org/wikipedia/commons/b/bf/Scalenus_anterior.png xref: SCTID:181742002 ! Entire scalenus anterior muscle [Term] id: UBERON:0008712 name: stylohyoid muscle def: "The stylohyoid muscle is a slender muscle, lying anterior, and superior of the posterior belly of the digastric muscle. It shares this muscle's innervation by the facial nerve." [Wikipedia:Stylohyoid_muscle] synonym: "stylohyoid" RELATED [Wikipedia:Stylohyoid_muscle] synonym: "stylohyoideus" RELATED [Wikipedia:Stylohyoid_muscle] synonym: "stylohyoideus muscle" RELATED [Wikipedia:Stylohyoid_muscle] synonym: "stylohyoideus muscles" RELATED [Wikipedia:Stylohyoid_muscle] synonym: "musculus stylohyoideus" RELATED [] is_a: UBERON:0008571 {source="FMA"} ! suprahyoid muscle xref: FMA:9625 ! stylohyoid xref: SCTID:244826001 ! Entire stylohyoid muscle relationship: innervated_by UBERON:0001647 {source="dbpedia"} ! facial nerve relationship: has_muscle_origin UBERON:0003960 {source="dbpedia"} ! styloid process of temporal bone synonym: "musculus stylohyoideus" RELATED LATIN [Wikipedia:Stylohyoid_muscle] relationship: has_muscle_insertion UBERON:0003997 {source="dbpedia", notes="greater cornu of hyoid bone"} ! hyoid bone greater horn xref: http://upload.wikimedia.org/wikipedia/commons/9/94/Musculi_colli_stylohyoideus.svg property_value: external_definition "The stylohyoid is a pharyngeal arch II muscle that participates in oral/pharygeal behaviors and is innervated by the stylohoid branch of the facial nerve and attaches to the stylohyal.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} [Term] id: UBERON:0010945 name: jugulohyoideus muscle def: "runs from the processus jugularis to the os stylohyoideum; innervated with the ramus jugulohyoideus from the nervus facialis" [PMID:7839797] comment: See also: stylohyoid muscle synonym: "musculus jugulohyoideus" RELATED [] synonym: "jugulohyoideus" RELATED [] synonym: "jugulohyoid" RELATED [] synonym: "musculus occipitohyoideus" RELATED [] synonym: "occipitohyoideus" RELATED [] synonym: "occipitohyoid" RELATED [] is_a: UBERON:0002377 ! muscle of neck [Term] id: UBERON:0001573 name: styloglossus def: "The Styloglossus, the shortest and smallest of the three styloid muscles, arises from the anterior and lateral surfaces of the styloid process, near its apex, and from the stylomandibular ligament. Passing downward and forward between the internal and external carotid arteries, it divides upon the side of the tongue near its dorsal surface, blending with the fibers of the Longitudinalis inferior in front of the Hyoglossus; the other, oblique, overlaps the Hyoglossus and decussates with its fibers. [WP,unvetted]." [Wikipedia:Styloglossus] synonym: "syloglossus muscle" EXACT [] subset: uberon_slim xref: FMA:46692 ! Styloglossus xref: MA:0002387 ! styloglossus xref: ncithesaurus:Styloglossus ! Styloglossus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/1/16/Styloglossus.png/200px-Styloglossus.png xref: EMAPA:18279 ! styloglossus of extrinsic of skeletal muscle of tongue of pharynx of foregut xref: EMAPA:18884 ! styloglossus of extrinsic of skeletal muscle of tongue of pharynx of gut is_a: UBERON:0001575 {source="FMA"} ! extrinsic muscle of tongue relationship: innervated_by UBERON:0001650 {source="dbpedia"} ! hypoglossal nerve relationship: has_muscle_origin UBERON:0003960 {source="dbpedia"} ! styloid process of temporal bone synonym: "musculus styloglossus" RELATED LATIN [Wikipedia:Styloglossus] relationship: has_muscle_insertion UBERON:0001723 {source="dbpedia", notes="tip and sides of tongue"} ! tongue xref: http://upload.wikimedia.org/wikipedia/commons/1/16/Styloglossus.png property_value: external_definition "Styloglossus is a muscle that attaches to the tongue and stylohyal and is innervated by Cranial Nerve XII.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} xref: UMLS:C0224195 [Term] id: UBERON:0008804 name: stylopharyngeus muscle def: "The stylopharyngeus is a muscle in the head that stretches between the styloid process and the pharynx." [Wikipedia:Stylopharyngeus_muscle] synonym: "M. stylopharyngeus" RELATED [Wikipedia:Stylopharyngeus_muscle] synonym: "musculus stylopharyngeus" RELATED [Wikipedia:Stylopharyngeus_muscle] synonym: "stylopharyngeus" EXACT [Wikipedia:Stylopharyngeus_muscle] is_a: UBERON:0000933 {source="FMA"} ! pharyngeal muscle relationship: develops_from UBERON:0003114 {source="Wikipedia"} ! pharyngeal arch 3 xref: FMA:46664 ! stylopharyngeus xref: ncithesaurus:Stylopharyngeus ! Stylopharyngeus xref: SCTID:244806000 ! Entire stylopharyngeus muscle relationship: innervated_by UBERON:0001649 {source="dbpedia"} ! glossopharyngeal nerve relationship: has_muscle_origin UBERON:0003960 {source="dbpedia"} ! styloid process of temporal bone synonym: "musculus stylopharyngeus" RELATED LATIN [Wikipedia:Stylopharyngeus_muscle] relationship: has_muscle_insertion UBERON:0001738 {source="dbpedia", notes="thyroid cartilage"} ! thyroid cartilage xref: http://upload.wikimedia.org/wikipedia/commons/5/59/Musculusstylopharyngeus.png property_value: external_definition "The stylopharyngeus is a pharyngeal arch III muscle that participates in oral/pharyngeal behaviors and is innervated by the n. to stylopharyngeus branch of the glossopharyngeal n. and attaches to the hyoid apparatus and the pharynx.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} relationship: in_lateral_side_of UBERON:0001042 {source="FMA-abduced-lr"} ! chordate pharynx xref: UMLS:C1522014 [Term] id: UBERON:0010954 name: ceratohyoideus muscle def: "The ceratohyoideus is a muscle of Pharyngeal Arch III that participates in oral/pharyngeal behaviors and is innervated by the glossopharyngeal n. , and attaches to the ceratohyal part of the hyoid apparatus and also to a non-ceratohyal part of the hyoid apparatus.[FEED]" [http://www.feedexp.org] synonym: "ceratohyoideus" EXACT [FEED:FEED] is_a: UBERON:0000933 ! pharyngeal muscle relationship: innervated_by UBERON:0001649 ! glossopharyngeal nerve property_value: external_definition "The ceratohyoideus is a muscle of Pharyngeal Arch III that participates in oral/pharyngeal behaviors and is innervated by the glossopharyngeal n. , and attaches to the ceratohyal part of the hyoid apparatus and also to a non-ceratohyal part of the hyoid apparatus.[FEED]" xsd:string {ontology="FEED", date_retrieved="2012-07-02", url="http://www.feedexp.org"} [Term] id: UBERON:0008772 name: proximal epiphysis of tibia synonym: "head of tibia" EXACT [FMA:33113] synonym: "proximal end of tibia" EXACT [FMA:33113] synonym: "upper end of tibia" EXACT [FMA:33113] intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0000979 ! tibia xref: FMA:33113 ! proximal epiphysis of tibia xref: SCTID:302526005 ! Entire upper end of tibia xref: ncithesaurus:Head_of_the_Tibia ! Head of the Tibia def: "A proximal epiphysis that is part of a tibia." [OBOL:automatic] xref: UMLS:C0932431 [Term] id: UBERON:0008775 name: proximal epiphysis of fibula def: "A proximal epiphysis that is part of a fibula." [OBOL:automatic] synonym: "head of fibula" EXACT [FMA:33729] synonym: "proximal end of fibula" EXACT [FMA:33729] synonym: "upper end of fibula" EXACT [FMA:33729] intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001446 ! fibula xref: FMA:33729 ! proximal epiphysis of fibula xref: SCTID:182080006 ! Entire head of fibula xref: ncithesaurus:Head_of_the_Fibula ! Head of the Fibula xref: galen:HeadOfFibula ! head of fibula property_value: external_definition "The upper extremity or head of the fibula is of an irregular quadrate form, presenting above a flattened articular surface, directed upward, forward, and medialward, for articulation with a corresponding surface on the lateral condyle of the tibia. On the lateral side is a thick and rough prominence continued behind into a pointed eminence, the apex, which projects upward from the posterior part of the head. The prominence, at its upper and lateral part, gives attachment to the tendon of the Biceps femoris and to the fibular collateral ligament of the knee-joint, the ligament dividing the tendon into two parts. The remaining part of the circumference of the head is rough, for the attachment of muscles and ligaments. It presents in front a tubercle for the origin of the upper and anterior fibers of the Peronæus longus, and a surface for the attachment of the anterior ligament of the head; and behind, another tubercle, for the attachment of the posterior ligament of the head and the origin of the upper fibers of the Soleus[Wikipedia:Head_of_fibula]." xsd:string {source="Wikipedia:Head_of_fibula"} xref: UMLS:C0223908 [Term] id: UBERON:0008783 name: dorsal venous arch def: "The dorsal venous arch of the foot is a superficial vein that connects the small saphenous vein and the great saphenous vein. Anatomically, it is defined by where the dorsal veins of the first and fifth digit, respectively, meet the great saphenous vein and small saphenous vein." [Wikipedia:Dorsal_venous_arch_of_the_foot] synonym: "arcus venosus dorsalis pedis" EXACT [Wikipedia:Dorsal_venous_arch_of_the_foot] synonym: "dorsal venous arch of foot" EXACT [FMA:44356] is_a: UBERON:0001638 {source="MA"} ! vein xref: MA:0002110 ! dorsal venous arch xref: FMA:44356 ! dorsal venous arch of foot xref: SCTID:231189006 ! Entire dorsal venous arch of foot synonym: "arcus venosus dorsalis pedis" RELATED LATIN [Wikipedia:Dorsal_venous_arch_of_the_foot] xref: http://upload.wikimedia.org/wikipedia/commons/4/4e/Gray581.png [Term] id: UBERON:0008790 ! rugal fold name: rugal fold def: "a ridge or fold, such as the rugae of the stomach, which are large folds in the mucous membrane of that organ." [Wikipedia:Rugae, http://medical-dictionary.thefreedictionary.com/Rugal+folds] synonym: "ruga" EXACT [Wikipedia:Rugae] synonym: "rugae" RELATED PLURAL [Wikipedia:Rugae] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000344 ! mucosa [Term] id: UBERON:0008791 name: rugal fold of stomach synonym: "gastric ruga" EXACT [FMA:15106] synonym: "gastric rugae" EXACT PLURAL [FMA:15106] synonym: "ruga of stomach" EXACT [FMA:15106] xref: FMA:15106 ! rugal fold of stomach xref: ncithesaurus:Gastric_Rugae ! gastric rugae intersection_of: UBERON:0008790 ! rugal fold intersection_of: part_of UBERON:0000945 ! stomach xref: SCTID:268518001 ! Entire gastric rugae synonym: "gastric ruga(e)" RELATED [FMA:15106] def: "A rugal fold that is part of a stomach." [OBOL:automatic] relationship: part_of UBERON:0001199 {is_inferred="true", source="reference_0000032"} ! mucosa of stomach xref: UMLS:C0227199 [Term] id: UBERON:0008798 name: rugal fold of vagina synonym: "vaginal ruga" EXACT [FMA:19991] synonym: "ruga of vagina" EXACT [FMA:19991] xref: FMA:19991 ! ruga of vagina intersection_of: UBERON:0008790 ! rugal fold intersection_of: part_of UBERON:0000996 ! vagina def: "A rugal fold that is part of a vagina." [OBOL:automatic] relationship: part_of UBERON:0004983 {is_inferred="true", source="reference_0000032"} ! mucosa of vagina [Term] id: UBERON:0008799 name: transverse palatine fold def: "a masticatory vestige on the hard palate; one of several irregular, sometimes branching, crests of soft tissue that radiate from the region of the incisive papillae at their most anterior parts and extend a slight distance backward, crossing the hard palate and reaching laterally for variable distances." [http://www.drugs.com/dict/transverse-palatine-fold.html] comment: note that this class refers to the singular and the FMA class refers to the set. In future this class may be split. synonym: "palatine fold" EXACT [FMA:75652] synonym: "plica palatina transversa" EXACT [http://www.drugs.com/dict/transverse-palatine-fold.html] synonym: "ruga palatina" EXACT [http://www.drugs.com/dict/transverse-palatine-fold.html] synonym: "transverse palatine ridge" EXACT [http://www.drugs.com/dict/transverse-palatine-fold.html] synonym: "palatine rugae" EXACT PLURAL [FMA:75652] synonym: "rugae of palate" EXACT PLURAL [UBERON:cjm] synonym: "ruga of palate" EXACT [UBERON:cjm] synonym: "plicae palatinae transversae" EXACT LATIN [FMA:TA, FMA:75652] synonym: "rugae palatinae" EXACT PLURAL [FMA:TA, FMA:75652] synonym: "transverse palatine folds" EXACT PLURAL [FMA:75652] synonym: "transverse palatine folds set" EXACT PLURAL [FMA:75652] synonym: "palatal rugae" EXACT [MP:0009652] intersection_of: UBERON:0008790 ! rugal fold intersection_of: part_of UBERON:0003216 ! hard palate xref: FMA:75652 ! set of transverse palatine folds synonym: "set of transverse palatine folds" RELATED [FMA:75652] relationship: part_of UBERON:0005046 {is_inferred="true", source="reference_0000032"} ! mucosa of hard palate [Term] id: UBERON:0009207 name: geschmacksstreifen def: "Area on the rostral portion of the soft palate rich in tastebuds (Miller and Spangler 1982)." [PMID:19295142] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001716 ! secondary palate [Term] id: UBERON:0008805 name: gingival groove def: "The gingival sulcus is an area of potential space between a tooth and the surrounding gingival tissue and is lined by sulcular epithelium. The depth of the sulcus (Latin for groove) is bounded by two entities: apically by the gingival fibers of the connective tissue attachment and coronally by the free gingival margin." [Wikipedia:Gingival_sulcus] synonym: "gingival sulcus" EXACT [FMA:74580] synonym: "sulcus gingivalis" EXACT LATIN [FMA:TA] intersection_of: UBERON:0006800 ! anatomical line intersection_of: adjacent_to UBERON:0001828 ! gingiva intersection_of: adjacent_to UBERON:0001091 ! tooth xref: FMA:74580 ! gingival groove xref: http://upload.wikimedia.org/wikipedia/commons/5/5e/Gingival_sulcus.PNG xref: SCTID:245753001 ! Entire gingival sulcus synonym: "sulcus gingivalis" RELATED LATIN [Wikipedia:Gingival_sulcus] [Term] id: UBERON:0008806 name: buccal funnel synonym: "suctorial disk" EXACT [] synonym: "suctorial disc" EXACT [] is_a: UBERON:0000166 ! oral opening relationship: only_in_taxon NCBITaxon:117569 ! Hyperoartia [Term] id: UBERON:0008824 name: duct of epididymis synonym: "epididymis duct" EXACT [FMA:18297] is_a: UBERON:0000058 {source="FMA"} ! duct relationship: part_of UBERON:0001301 {source="FMA"} ! epididymis intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001301 ! epididymis xref: FMA:18297 ! duct of epididymis xref: MA:0001735 ! epididymal duct synonym: "epididymal duct" EXACT [MA:0001735] xref: SCTID:279623004 ! Entire duct of epididymis xref: ncithesaurus:Duct_of_the_Epididymis ! Duct of the Epididymis def: "A duct that is part of a epididymis." [OBOL:automatic] xref: UMLS:C0458632 [Term] id: UBERON:0008826 name: pulmonary surfactant def: "Secretion produced by Type 2 pulmonary alveolar cell." [FMA:62780] synonym: "alveolar surfactant" EXACT [FMA:62780] synonym: "lung surfactant" EXACT [MA:0002534] is_a: UBERON:0006538 {source="MA"} ! respiratory system fluid/secretion xref: FMA:62780 ! pulmonary surfactant xref: MA:0002534 ! lung surfactant xref: ncithesaurus:Lung_Surfactant ! Lung Surfactant xref: UMLS:C0034085 [Term] id: UBERON:0008994 name: equine glandular stomach def: "Stomach found in horses; includes cardiac, proper gastric and pyloric glandular zones." [BTO:0003791] comment: Editor notes: We have a distinct class for 'glandular region of stomach'. We may want to merge into this class, even though this is not considered a distinct stomach. synonym: "stomachus glandularis" RELATED [BTO:0003791] is_a: UBERON:0000945 {source="BTO"} ! stomach xref: BTO:0003791 ! glandular stomach [Term] id: UBERON:0008827 name: forestomach comment: This class is based on the murine structure. Other groups, such as cetaceans, also have a forestomach (which is essentially an enlargement of the esophagus) synonym: "murine forestomach" RELATED [] is_a: UBERON:0011954 ! stomach non-glandular region relationship: part_of UBERON:0000945 {source="MA"} ! stomach relationship: continuous_with UBERON:0007650 ! esophagogastric junction relationship: continuous_with UBERON:0011953 ! stomach glandular region xref: MA:0001606 ! forestomach xref: ncithesaurus:Forestomach ! Forestomach xref: UMLS:C0033745 property_value: external_definition "The mouse stomach contains two well-defined areas, a (nonglandular) forestomach and a glandular stomach, which are separated by the limiting ridge (margo plicatus)[http://ctrgenpath.net/static/atlas/mousehistology/Windows/digestive/forestomach.html]." xsd:string {source="http://ctrgenpath.net/static/atlas/mousehistology/Windows/digestive/forestomach.html"} [Term] id: UBERON:0012270 ! forestomach-glandular stomach junction name: forestomach-glandular stomach junction synonym: "margo plicatus" RELATED [UBERON:0008827] synonym: "limiting ridge of stomach" RELATED [UBERON:0008827] synonym: "squamocolumnar junction with the glandular stomach" RELATED [] synonym: "forestomach - glandular stomach squamocolumnar junction" RELATED [] synonym: "squamo-columnar junction between forestomach and glandular stomach" RELATED [] is_a: UBERON:0007651 ! anatomical junction relationship: part_of UBERON:0000945 ! stomach relationship: continuous_with UBERON:0008827 ! forestomach relationship: continuous_with UBERON:0011953 ! stomach glandular region xref: SCTID:67204008 [Term] id: UBERON:0008829 name: cerebellum external granule cell layer def: "transient layer of the cerebellar cortex present during development which is composed of dividing and migrating granule cells[MP]. The granule neurons migrate from the exterior layer to form an inner layer known as the internal granule layer. The external granular layer ceases to exist in the mature cerebellum, leaving only granule cells in the internal granule layer" [MP:0000874, Wikipedia:Anatomy_of_the_cerebellum#Development] is_a: UBERON:0002956 {source="MA"} ! granular layer of cerebellar cortex xref: MA:0000994 ! cerebellum external granule cell layer xref: NIF_GrossAnatomy:birnlex_797 ! Outer granular layer of cerebellar cortex [Term] id: UBERON:0008830 name: cerebellum internal granule cell layer is_a: UBERON:0002956 {source="MA"} ! granular layer of cerebellar cortex xref: MA:0000995 ! cerebellum internal granule cell layer xref: NIF_GrossAnatomy:birnlex_790 ! Inner granular layer of cerebellar cortex xref: ncithesaurus:Internal_Granular_Layer_of_the_Cerebellum ! Internal Granular Layer of the Cerebellum xref: UMLS:C1708540 [Term] id: UBERON:0008833 name: great auricular nerve def: "The great auricular nerve originates from the cervical plexus, composed of branches of spinal nerves C2 and C3. It provides sensory innervation for the skin over parotid gland and mastoid process, and both surfaces of the outer ear." [Wikipedia:Great_auricular_nerve] comment: todo - check MA grouping; in MA this is part_of pinna - should this be a different relationship? synonym: "great auricular" RELATED [Wikipedia:Great_auricular_nerve] synonym: "greater auricular nerve" RELATED [Wikipedia:Great_auricular_nerve] xref: Wikipedia:Great_auricular_nerve ! great auricular nerve is_a: UBERON:0002003 {source="FMA"} ! peripheral nerve relationship: branch_of UBERON:0003725 {source="FMA"} ! cervical plexus xref: MA:0001232 ! auricular nerve synonym: "auricular nerve" EXACT [MA:0001232] xref: FMA:6872 ! great auricular nerve xref: SCTID:181110003 ! Entire great auricular nerve synonym: "nervus auricularis magnus" RELATED LATIN [Wikipedia:Great_auricular_nerve] xref: http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray805.png [Term] id: UBERON:0011322 name: mylohyoid nerve def: "A nerve that innervates the mylohyoid muscle and the anterior belly of the digastric muscle." [Wikipedia:Mylohyoid_nerve] synonym: "nervus mylohyoideus" EXACT LATIN [Wikipedia:Mylohyoid_nerve] synonym: "nerve to mylohyoid" RELATED [Wikipedia:Mylohyoid_nerve] synonym: "branch of inferior alveolar nerve to mylohyoid" EXACT [FMA:53247] synonym: "mylodigastric nerve" EXACT [FMA:53247] synonym: "mylohyoid branch of inferior alveolar nerve" EXACT [FMA:53247] synonym: "nerve to mylohyoid" EXACT [FMA:53247] synonym: "nervus mylohyoideus" EXACT LATIN [FMA:TA] xref: FMA:53247 ! mylohyoid nerve xref: SCTID:280269007 ! Mylohyoid nerve is_a: UBERON:0002003 ! peripheral nerve [Term] id: UBERON:0011325 name: pharyngeal nerve plexus def: "The pharyngeal plexus is a network of nerve fibers innervating most of the palate, larynx, and pharynx. It is located on the surface of the middle pharyngeal constrictor muscle." [Wikipedia:Pharyngeal_plexus_of_vagus_nerve] synonym: "pharyngeal nerve plexus" EXACT [FMA:82453] synonym: "vagus nerve pharyngeal plexus" EXACT [] synonym: "plexus pharyngeus nervi vagi" EXACT LATIN [Wikipedia:Pharyngeal_plexus_of_vagus_nerve] synonym: "pharyngeal plexus of vagus nerve" EXACT [Wikipedia:Pharyngeal_plexus_of_vagus_nerve] is_a: UBERON:0001816 {source="FMA"} ! autonomic nerve plexus xref: FMA:82453 ! pharyngeal nerve plexus xref: SCTID:369429008 ! Entire vagus nerve pharyngeal plexus [Term] id: UBERON:0008854 name: root of molar tooth def: "the part of a molar tooth that is implanted in the gum; mandibular and maxillary molars usually have two and three roots, respectively." [MP:0011165] synonym: "molar tooth root" EXACT [FMA:85302] synonym: "molar root" EXACT [FMA:85302] is_a: UBERON:0003677 {source="FMA"} ! tooth root intersection_of: UBERON:0003677 ! tooth root intersection_of: part_of UBERON:0003655 ! molar tooth xref: FMA:85302 ! root of molar tooth [Term] id: UBERON:0008855 name: placenta metrial gland def: "group of granular epithelial cells in the uterine muscle beneath the placenta that develops during pregnancy in rodents and some other species." [MP:0010777] is_a: UBERON:0002530 ! gland relationship: part_of UBERON:0002450 {source="MP"} ! decidua xref: MA:0001723 ! placenta metrial gland relationship: never_in_taxon NCBITaxon:9443 {source="MP:0010777"} ! Primates subset: organ_slim [Term] id: UBERON:0008856 ! stomach muscularis externa name: stomach muscularis externa def: "the smooth muscle layer of the stomach wall that functions to churn and mix food and gastric secretions as well as to move food along the digestive tract to the intestines" [MP:0010779] synonym: "muscle layer of stomach" EXACT [FMA:14909] synonym: "gastric muscularis" EXACT [FMA:14909] synonym: "muscularis externa of stomach" EXACT [FMA:14909] synonym: "tunica muscularis (gaster)" EXACT [FMA:14909] synonym: "tunica muscularis gastris" EXACT [] is_a: UBERON:0001135 {source="MP"} ! smooth muscle tissue intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0001167 ! wall of stomach relationship: part_of UBERON:0001167 {source="FMA"} ! wall of stomach xref: FMA:14909 ! muscle layer of stomach xref: SCTID:362132003 ! Entire gastric muscularis [Term] id: UBERON:0004220 name: large intestine smooth muscle def: "A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] comment: MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa synonym: "involuntary muscle of large intestine" EXACT [OBOL:automatic] synonym: "large intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "large intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "large intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of large intestine" EXACT [OBOL:automatic] synonym: "smooth muscle of large intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of large intestine" EXACT [OBOL:automatic] xref: MA:0001547 ! large intestine smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 {source="MA"} ! wall of large intestine relationship: overlaps UBERON:0011198 {notes="consider merging"} ! muscle layer of large intestine [Term] id: UBERON:0004239 name: small intestine smooth muscle def: "A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] comment: MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa synonym: "involuntary muscle of small bowel" EXACT [OBOL:automatic] synonym: "involuntary muscle of small intestine" EXACT [OBOL:automatic] synonym: "non-striated muscle of small bowel" EXACT [OBOL:automatic] synonym: "non-striated muscle of small intestine" EXACT [OBOL:automatic] synonym: "small bowel involuntary muscle" EXACT [OBOL:automatic] synonym: "small bowel non-striated muscle" EXACT [OBOL:automatic] synonym: "small bowel smooth muscle" EXACT [OBOL:automatic] synonym: "small bowel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "small intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "small intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "small intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of small bowel" EXACT [OBOL:automatic] synonym: "smooth muscle of small intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of small bowel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of small intestine" EXACT [OBOL:automatic] xref: MA:0001559 ! small intestine smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 ! wall of small intestine relationship: overlaps UBERON:0011201 {notes="consider merging"} ! muscle layer of small intestine [Term] id: UBERON:0004221 name: intestine smooth muscle def: "A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]." [OBOL:automatic] comment: MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa synonym: "intestinal smooth muscle" RELATED [BTO:0000643] synonym: "bowel involuntary muscle" EXACT [OBOL:automatic] synonym: "bowel non-striated muscle" EXACT [OBOL:automatic] synonym: "bowel smooth muscle" EXACT [OBOL:automatic] synonym: "bowel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bowel" EXACT [OBOL:automatic] synonym: "involuntary muscle of intestine" EXACT [OBOL:automatic] synonym: "non-striated muscle of bowel" EXACT [OBOL:automatic] synonym: "non-striated muscle of intestine" EXACT [OBOL:automatic] synonym: "smooth muscle of bowel" EXACT [OBOL:automatic] synonym: "smooth muscle of intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bowel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of intestine" EXACT [OBOL:automatic] xref: MA:0001539 ! intestine smooth muscle xref: ncithesaurus:Intestinal_Smooth_Muscle_Tissue ! Intestinal Smooth Muscle Tissue xref: BTO:0000643 ! intestinal muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001262 ! wall of intestine relationship: overlaps UBERON:0012367 {notes="consider merging"} ! muscle layer of intestine xref: UMLS:C1708547 [Term] id: UBERON:0004222 name: stomach smooth muscle def: "A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of stomach" EXACT [OBOL:automatic] synonym: "involuntary muscle of ventriculus" EXACT [OBOL:automatic] synonym: "non-striated muscle of stomach" EXACT [OBOL:automatic] synonym: "non-striated muscle of ventriculus" EXACT [OBOL:automatic] synonym: "smooth muscle of stomach" EXACT [OBOL:automatic] synonym: "smooth muscle of ventriculus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of stomach" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of ventriculus" EXACT [OBOL:automatic] synonym: "stomach involuntary muscle" EXACT [OBOL:automatic] synonym: "stomach non-striated muscle" EXACT [OBOL:automatic] synonym: "stomach smooth muscle tissue" EXACT [OBOL:automatic] synonym: "ventriculus involuntary muscle" EXACT [OBOL:automatic] synonym: "ventriculus non-striated muscle" EXACT [OBOL:automatic] synonym: "ventriculus smooth muscle" EXACT [OBOL:automatic] synonym: "ventriculus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gastric smooth muscle" RELATED [MA:0001627] synonym: "gastric muscle" RELATED [BTO:0001818] synonym: "stomach muscle" RELATED [BTO:0001818] xref: MA:0001627 ! stomach smooth muscle xref: BTO:0001818 ! stomach smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0001167 ! wall of stomach [Term] id: UBERON:0012367 ! muscle layer of intestine name: muscle layer of intestine synonym: "intestinal muscularis propria" EXACT [FMA:15697] synonym: "muscularis externa of intestine" EXACT [FMA:15697] synonym: "smooth muscle of intestine" RELATED [] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001262 {source="FMA"} ! wall of intestine xref: FMA:15697 ! muscle layer of intestine def: "A muscle layer that is part of an intestine." [OBOL:automatic] [Term] id: UBERON:0011198 name: muscle layer of large intestine synonym: "muscular coat of large intestine" EXACT [FMA:14971] synonym: "muscular layer of large intestine" EXACT [FMA:14971] synonym: "muscularis externa of large intestine" EXACT [FMA:14971] synonym: "tunica muscularis intestini crassi" EXACT LATIN [FMA:TA] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 {source="FMA"} ! wall of large intestine xref: FMA:14971 ! muscle layer of large intestine xref: ncithesaurus:Large_Intestinal_Muscular_Coat ! large intestinal muscular coat def: "A muscle layer that is part of a large intestine." [OBOL:automatic] xref: UMLS:C0734205 [Term] id: UBERON:0011201 name: muscle layer of small intestine synonym: "muscular coat of small intestine" EXACT [FMA:14932] synonym: "muscular layer of small intestine" EXACT [FMA:14932] synonym: "muscularis externa of small intestine" EXACT [FMA:14932] synonym: "small intestine muscularis propria" EXACT [FMA:14932] synonym: "tunica muscularis (intestinum tenue)" EXACT [FMA:14932] synonym: "tunica muscularis intestini tenuis" EXACT LATIN [FMA:TA] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 {source="FMA"} ! wall of small intestine xref: FMA:14932 ! muscle layer of small intestine xref: ncithesaurus:Small_Intestinal_Muscular_Coat ! small intestinal muscular coat xref: SCTID:362145004 ! Entire small intestine muscularis propria def: "A muscle layer that is part of a small intestine." [OBOL:automatic] xref: UMLS:C0227269 [Term] id: UBERON:0012377 name: muscle layer of jejunum synonym: "smooth muscle of jejunum" RELATED [UBERON:cjm] synonym: "muscularis externa of jejunum" EXACT [FMA:14951] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0002115 ! jejunum xref: FMA:14951 ! muscle layer of jejunum [Term] id: UBERON:0012488 name: muscle layer of duodenum synonym: "duodenal muscularis propria" EXACT [FMA:14944] synonym: "muscularis externa of duodenum" EXACT [FMA:14944] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0002114 ! duodenum xref: FMA:14944 ! muscle layer of duodenum xref: SCTID:362147007 ! Entire duodenal muscularis propria [Term] id: UBERON:0012489 name: muscle layer of colon synonym: "colonic muscularis propria" EXACT [FMA:14986] synonym: "muscular coat of colon" EXACT [FMA:14986] synonym: "muscular layer of colon" EXACT [FMA:14986] synonym: "muscularis externa of colon" EXACT [FMA:14986] synonym: "tunica muscularis coli" EXACT [FMA:TA] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0001155 ! colon xref: FMA:14986 ! muscle layer of colon xref: SCTID:362158003 ! Entire colonic muscularis propria [Term] id: UBERON:0012490 name: muscle layer of anal canal synonym: "anal canal muscularis propria" EXACT [] synonym: "muscular coat of anal canal" EXACT [] synonym: "muscular layer of anal canal" EXACT [] synonym: "muscularis externa of anal canal" EXACT [] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0000159 ! anal canal xref: SCTID:362171000 ! Entire muscularis propria of anal canal xref: FMA:15708 ! Muscle layer of anal canal viewed anatomically [Term] id: UBERON:0012419 name: taenia coli def: "The taeniae coli (also teniae coli) are three separate longitudinal ribbons of smooth muscle on the outside of the ascending, transverse, descending and sigmoid colons. They are visible, and can be seen just below the serosa or fibrosa. They are the Mesocolic, Free and Omental Coli. The teniae coli contracts length wise to produce the haustra, the bulges in the colon. The bands converge at the root of the vermiform appendix and the rectum. These bands correspond to the outer layer of the muscularis externa, in other portions of the digestive tract." [Wikipedia:Taenia_coli] synonym: "longitudinal bands" RELATED [Wikipedia:Taenia_coli] synonym: "taeniae coli" RELATED [Wikipedia:Taenia_coli] synonym: "tenia coli" RELATED [Wikipedia:Taenia_coli] synonym: "teniae coli" RELATED [Wikipedia:Taenia_coli] synonym: "longitudinal band of large intestine muscularis" EXACT [FMA:15041] is_a: UBERON:0001135 ! smooth muscle tissue relationship: part_of UBERON:0011198 {source="FMA"} ! muscle layer of large intestine xref: FMA:15041 ! taenia coli xref: SCTID:362160001 ! Entire taenia coli [Term] id: UBERON:0004228 name: urinary bladder smooth muscle def: "A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder" EXACT [OBOL:automatic] synonym: "urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] xref: MA:0001697 ! urinary bladder smooth muscle xref: BTO:0001849 ! urinary bladder smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001255 ! urinary bladder synonym: "urinary bladder muscle" EXACT [MA:0001697] [Term] id: UBERON:0012378 name: muscle layer of urinary bladder synonym: "bladder muscular coat" EXACT [] synonym: "muscle layer of urinary bladder" EXACT [FMA:15930] synonym: "muscular coat of bladder" EXACT [FMA:15930] synonym: "muscular coat of urinary bladder" EXACT [FMA:15930] synonym: "muscular layer of urinary bladder" EXACT [FMA:15930] synonym: "tunica musculari vesicae" EXACT [FMA:TA] synonym: "tunica muscularis (vesica urinaria)" EXACT [FMA:TA] synonym: "muscular layer of bladder" EXACT [FMA:15930] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001256 {source="FMA"} ! wall of urinary bladder relationship: has_part UBERON:0004228 ! urinary bladder smooth muscle xref: FMA:15930 ! muscular layer of bladder xref: ncithesaurus:Bladder_Muscular_Coat ! bladder muscular coat xref: UMLS:C1288327 [Term] id: UBERON:0008857 name: stomach smooth muscle circular layer def: "the middle layer of the muscularis; it is continuous with the circular layer of the esophagus, but is absent in the fundus and lies concentric to the longitudinal axis of the stomach; the circular layer is normally tonically constricted forming a functional pyloric sphincter, which controls the movement of chyme into the duodenum" [MP:0010780] comment: todo - check is_a: UBERON:0012368 ! circular muscle layer is_a: UBERON:0001135 {source="MP"} ! smooth muscle tissue relationship: part_of UBERON:0008856 ! stomach muscularis externa synonym: "circular layer of gastric muscularis" EXACT [FMA:14911] synonym: "stratum circulare (tunica muscularis)(gaster)" EXACT [FMA:14911] synonym: "stratum circulare gastris" EXACT [] xref: FMA:14911 ! circular muscle layer of stomach xref: MA:0001628 ! stomach smooth muscle circular layer xref: SCTID:2746007 ! Circular layer of gastric muscularis synonym: "circular muscle layer of stomach" EXACT [FMA:14911] [Term] id: UBERON:0012398 name: large intestine smooth muscle circular layer synonym: "circular muscle layer of segment of large intestine" RELATED [FMA:81160] intersection_of: UBERON:0012368 ! circular muscle layer intersection_of: part_of UBERON:0004220 ! large intestine smooth muscle xref: MA:0001548 ! large intestine smooth muscle circular layer xref: FMA:81160 ! circular muscle layer of segment of large intestine [Term] id: UBERON:0012399 name: large intestine smooth muscle longitudinal layer synonym: "longitudinal muscle layer of zone of large intestine" RELATED [FMA:63637] intersection_of: UBERON:0012369 ! longitudinal muscle layer intersection_of: part_of UBERON:0004220 ! large intestine smooth muscle xref: MA:0001549 ! large intestine smooth muscle longitudinal layer xref: FMA:63637 ! longitudinal muscle layer of zone of large intestine [Term] id: UBERON:0012401 name: small intestine smooth muscle circular layer synonym: "circular layer of small intestine muscularis propria" EXACT [FMA:14935] synonym: "circular muscle coat of small intestine" EXACT [FMA:14935] synonym: "circular muscle of small intestine" EXACT [FMA:14935] synonym: "short pitch helicoidal muscle layer of small intestine" EXACT [FMA:14935] synonym: "stratum circulare (tunica muscularis)(intestinum tenue)" EXACT [FMA:14935] synonym: "stratum helicoidale brevis gradus tunicae muscularis intestini tenuis" EXACT [FMA:TA] synonym: "circular muscle layer of small intestine" EXACT [FMA:14935] synonym: "circular layer of small intestine muscularis propria" EXACT [] intersection_of: UBERON:0012368 ! circular muscle layer intersection_of: part_of UBERON:0004239 ! small intestine smooth muscle relationship: part_of UBERON:0011201 {source="FMA"} ! muscle layer of small intestine xref: MA:0001560 ! small intestine smooth muscle circular layer xref: FMA:14935 ! circular muscle layer of small intestine xref: SCTID:54658003 ! Circular layer of small intestine muscularis propria [Term] id: UBERON:0012402 name: small intestine smooth muscle longitudinal layer synonym: "long pitch helicoidal muscle layer of small intestine" EXACT [FMA:14936] synonym: "longitudinal layer of small intestine muscularis propria" EXACT [FMA:14936] synonym: "longitudinal muscle coat of small intestine" EXACT [FMA:14936] synonym: "longitudinal muscle of small intestine" EXACT [FMA:14936] synonym: "stratum helicoidale longi gradus tunicae muscularis intestini tenuis" EXACT [FMA:TA] synonym: "stratum longitudinale (tunica muscularis) (intestinum tenue)" EXACT [FMA:14936] synonym: "longitudinal muscle layer of small intestine" EXACT [FMA:14936] synonym: "longitudinal layer of small intestine muscularis propria" EXACT [] intersection_of: UBERON:0012369 ! longitudinal muscle layer intersection_of: part_of UBERON:0004239 ! small intestine smooth muscle relationship: part_of UBERON:0011201 {source="FMA"} ! muscle layer of small intestine xref: MA:0001561 ! small intestine smooth muscle longitudinal layer xref: FMA:14936 ! longitudinal muscle layer of small intestine xref: SCTID:59150006 ! Longitudinal layer of small intestine muscularis propria [Term] id: UBERON:0012416 name: respiratory system arterial smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003643 ! respiratory system arterial blood vessel xref: MA:0001802 ! respiratory system arterial smooth muscle [Term] id: UBERON:0012418 name: respiratory system venous smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003476 ! respiratory system venous blood vessel xref: MA:0001812 ! respiratory system venous smooth muscle [Term] id: UBERON:0000424 name: gastric pit def: "Gastric pits are indentations in the stomach which denote entrances to the gastric glands. They are deeper in the pylorus than they are in the other parts of the stomach. The human stomach has several million of these pits." [Wikipedia:Gastric_pits] alt_id: UBERON:0000425 synonym: "gastric foveola" EXACT [FMA:62947] synonym: "foveola gastrica" RELATED [BTO:0002364] synonym: "foveolae gastricae" EXACT PLURAL [FMA:TA, FMA:76583] xref: BTO:0002364 xref: FMA:62947 ! Gastric foveola xref: ncithesaurus:Gastric_Pit ! Gastric Pit is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001199 {source="BTO"} ! mucosa of stomach xref: SCTID:268426007 ! Entire gastric foveola synonym: "foveolae gastricae" RELATED LATIN [Wikipedia:Gastric_pits] xref: http://upload.wikimedia.org/wikipedia/commons/7/73/Illu_stomach_layers.jpg xref: UMLS:C0227203 [Term] id: UBERON:0000325 ! gastric gland name: gastric gland def: "any of the branched tubules in the inner lining of the stomach that secrete gastric juice and protective mucus." [] xref: BTO:0000503 xref: FMA:14919 ! Gastric gland is_a: UBERON:0002365 {source="cjm"} ! exocrine gland relationship: part_of UBERON:0006924 {source="ISBN10:0073040584"} ! stomach glandular epithelium subset: organ_slim subset: grouping_class [Term] id: UBERON:0008859 name: cardiac gastric gland def: "A gastric gland in the cardiac region of the stomach; cardiac glands are fewer in number than in the fundus and body, and secrete mucin which coats the stomach and protects it[MP]" [MP:0010795, Wikipedia:Cardiac_glands] comment: Consistency note: Kardong places this in the glandular epithelium, FMA more generally in the mucosa synonym: "gardiac gland" EXACT [ISBN10:0073040584] synonym: "gastric gland of cardia" EXACT [FMA:14920] synonym: "glandula cardiaca (gaster)" EXACT [FMA:14920] intersection_of: UBERON:0000325 ! gastric gland intersection_of: part_of UBERON:0001162 ! cardia of stomach relationship: has_part CL:0000319 {source="Kardong"} ! mucus secreting cell relationship: part_of UBERON:0004996 {source="FMA"} ! mucosa of cardia of stomach xref: SCTID:8894005 ! Gastric cardiac gland xref: FMA:14920 ! Gastric cardiac gland subset: organ_slim synonym: "gastric cardiac gland" EXACT [FMA:14920] synonym: "cardiac gland" RELATED [FMA:14920] property_value: external_definition "The cardiac glands of the stomach secrete primarily mucus. They are few in number and occur close to the cardiac orifice where the esophagus joins the stomach. In general, they are more shallow than those in the other parts of the stomach. They are of two kinds: (1) simple tubular glands resembling those of the pyloric end of the stomach, but with short ducts. (2) compound racemose glands resembling the duodenal glands. The cardiac gland is both innervated by the parasympathetic and symapthetic nerve fibres of the autonomic nervous system[Wikipedia:Cardiac_glands]." xsd:string {source="Wikipedia:Cardiac_glands"} [Term] id: UBERON:0010038 ! fundic gastric gland name: fundic gastric gland def: "The fundus glands (or fundic glands, or gastric glands) are found in the body and fundus of the stomach. They are simple tubes, two or more of which open into a single duct." [Wikipedia:Fundic_glands] comment: Editor notes: Consider FMA:14923 ! Principal gland of fundus of stomach. Added part_of to mucosa to be consistent with FMA pattern (note that Kardong places this in the glandular epithelium) synonym: "fundus gland" EXACT [] synonym: "fundal gland" EXACT [] synonym: "gastric fundus gland" EXACT [] synonym: "gastric fundal gland" EXACT [] synonym: "gastric gland of fundus of stomach" EXACT [] intersection_of: UBERON:0000325 ! gastric gland intersection_of: part_of UBERON:0001160 ! fundus of stomach relationship: has_part CL:0000319 {source="Kardong"} ! mucus secreting cell relationship: has_part CL:0000162 {source="Kardong"} ! parietal cell relationship: has_part CL:0000155 {source="Kardong"} ! peptic cell relationship: part_of UBERON:0004994 ! mucosa of fundus of stomach xref: ncithesaurus:Fundic_Gland ! Fundic Gland xref: SCTID:268338004 ! Entire gastric fundal gland synonym: "glandulae gastricae" RELATED LATIN [Wikipedia:Fundic_glands] xref: http://upload.wikimedia.org/wikipedia/commons/d/d7/Fundic_gland_polyp_%281%29.jpg xref: UMLS:C0017130 [Term] id: UBERON:0009971 name: principal gastric gland def: "one of the gastric glands that secretes the hydrochloric acid of the gastric juice[Stedman's]." [http://www.drugs.com/dict/acid-gland.html, MP:0003892] comment: AO notes: FMA has this as part of both the fundus and the body, but these are largely spatially disjoint. synonym: "glandula gastrica propria" EXACT [FMA:14921] synonym: "main gastric gland" EXACT [FMA:14921] synonym: "oxyntic gland" EXACT [FMA:14921] synonym: "gastric gland" BROAD [MP:0003892] synonym: "Wassman gland" RELATED [MP:0003892] synonym: "gastric follicle" RELATED [MP:0003892] synonym: "acid gland" EXACT [http://www.drugs.com/dict/acid-gland.html] is_a: UBERON:0000325 {source="FMA"} ! gastric gland xref: FMA:14921 ! principal gastric gland xref: FMA:14923 ! Principal gland of fundus of stomach synonym: "principal gland of fundus of stomach" EXACT [FMA:14923] [Term] id: UBERON:0008860 name: intermediate gastric gland def: "any of the branched tubular glands in the mucosa of the fundus and body of the stomach that secrete most of the digestive substances secreted by the stomach" [MP:0010796] comment: check me is_a: UBERON:0000325 {source="Obol"} ! gastric gland relationship: part_of UBERON:0001160 {source="MP"} ! fundus of stomach [Term] id: UBERON:0008861 name: pyloric gastric gland def: "the gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]." [MP:0010797, Wikipedia:Pyloric_gland] comment: Editors note: check relationship to pylorus vs antrum synonym: "pyloric gland" EXACT [FMA:14922] synonym: "pyloric antrum gland" EXACT [OBOL:automatic] xref: http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray1054.png intersection_of: UBERON:0000325 ! gastric gland intersection_of: part_of UBERON:0001166 ! pylorus relationship: part_of UBERON:0004998 ! mucosa of pylorus relationship: has_part CL:0000319 {source="Kardong"} ! mucus secreting cell relationship: has_quality PATO:0001873 {source="Wikipedia:Tubular_gland"} ! cylindrical xref: SCTID:70710007 ! Gastric pyloric gland xref: FMA:14922 ! pyloric gland xref: ncithesaurus:Pyloric_Gland ! Pyloric Gland synonym: "glandula pylorica" EXACT [FMA:14922] xref: UMLS:C0227239 [Term] id: UBERON:0008862 name: stomach smooth muscle inner oblique layer def: "the innermost layer of the muscularis; it is not present in all sections of the stomach but is clearly seen in the fundus and near the lesser curvature of the corpus; the oblique fibers disappear distally (towards the pyloric antrum); the oblique layer is responsible for creating the motion that churns and physically breaks down the food" [MP:0010804] is_a: UBERON:0002385 ! muscle tissue relationship: part_of UBERON:0008856 ! stomach muscularis externa [Term] id: UBERON:0008863 name: stomach smooth muscle outer longitudinal layer def: "the most superficial layer of the muscularis; it has two sections, a longitudinal layer that is common with the esophagus and ends in the corpus, and a longitudinal layer that originates in the corpus and spreads into the duodenum" [MP:0010805] is_a: UBERON:0012369 ! longitudinal muscle layer relationship: part_of UBERON:0008856 ! stomach muscularis externa [Term] id: UBERON:0008866 name: enamel knot def: "a transient cluster of cells in the central part of the dental epithelium facing the dental mesenchyme, which acts as an organizing center, providing positional information for tooth morphogenesis and regulating the growth of tooth cusps" [MP:0010864] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0003843 ! dental epithelium relationship: part_of UBERON:0005176 {source="MP"} ! tooth enamel organ [Term] id: UBERON:0002483 name: trabecular bone tissue def: "Cancellous bone, synonymous with trabecular bone or spongy bone, is one of the two types of osseous tissue that form bones. Compared to compact bone, which is the other type of osseous tissue, it has a higher surface area but is less dense, softer, weaker, and less stiff. It typically occupies the interior region of bones. Cancellous bone is highly vascular and frequently contains red bone marrow where hematopoiesis, which is the production of blood cells, occurs. The primary anatomical and functional unit of cancellous bone is the trabecula. Its Latin name is substantia spongiosa or substantia spongiosa ossium. The words cancellous and trabecular refer to the tiny, lattice-shaped that form the tissue. [WP,unvetted]." [Wikipedia:Trabecular_bone] comment: one of the two types of osseous tissue that form bones. Compared to compact bone, which is the other type of osseous tissue, it has a higher surface area but is less dense, softer, weaker, and less stiff. It typically occurs at the ends of long bones, proximal to joints and within the interior of vertebrae. Cancellous bone is highly vascular and frequently contains red bone marrow where hematopoiesis, which is the production of blood cells, occurs. The primary anatomical and functional unit of cancellous bone is the trabecula. subset: uberon_slim synonym: "cancellous bone" EXACT [MA:0002782, FMA:24019] synonym: "cancellous bone tissue" EXACT [] synonym: "spongy bone" EXACT [] synonym: "spongy bone tissue" EXACT [] synonym: "trabecular bone" EXACT [] synonym: "substantia spongiosa" EXACT [Wikipedia:Trabecular_bone] synonym: "substantia spongiosa ossium" EXACT [Wikipedia:Trabecular_bone] synonym: "cancellated bone" RELATED [BTO:0001700] synonym: "substantia trabecularis ossium" RELATED [BTO:0001700] synonym: "trabecular substance" RELATED [BTO:0001700] xref: FMA:24019 ! Trabecular bone xref: MA:0002782 ! trabecular bone xref: BTO:0001700 ! cancellous bone xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Illu_compact_spongy_bone.jpg/200px-Illu_compact_spongy_bone.jpg is_a: UBERON:0002481 ! bone tissue disjoint_from: UBERON:0001439 ! compact bone relationship: part_of UBERON:0002482 ! lamellar bone [Term] id: UBERON:0008867 ! trabecular network of bone name: trabecular network of bone def: "the network of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force" [MP:0010867] comment: Editor note: consider revision - we have 3 classes, the tissue itself, the network, and the spaces. synonym: "bone trabecula" RELATED [MP:0010867] synonym: "bone trabeculae" RELATED [MP:0010867] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0002483 {source="MP"} ! trabecular bone tissue xref: MP:0010867 ! bone trabecula xref: ncithesaurus:Bone_Trabeculae ! Bone Trabeculae xref: UMLS:C2826619 [Term] id: UBERON:0010076 name: network of trabecular spaces in bone tissue def: "Tissue cavity consisting of intercommunicating trabecular spaces in the cancellous bone." [FMA:259332] synonym: "trabecular network of bone tissue" EXACT [FMA:259332] intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0008867 ! trabecular network of bone relationship: part_of UBERON:0008867 ! trabecular network of bone xref: FMA:259332 ! network of trabecular spaces in bone tissue [Term] id: UBERON:0008875 name: hypodermis fat layer def: "the superficial portion of the subcutaneous tissue which is specialized for fat storage" [MP:0011156] is_a: UBERON:0002190 {source="MP"} ! subcutaneous adipose tissue relationship: part_of UBERON:0002072 ! hypodermis [Term] id: UBERON:0008876 name: hypodermis muscle layer def: "the skeletal muscle layer in the superficial fascia" [MP:0011157] is_a: UBERON:0001134 ! skeletal muscle tissue relationship: part_of UBERON:0002190 {source="MP"} ! subcutaneous adipose tissue [Term] id: UBERON:0008877 name: epidermal-dermal junction def: "the multi-layer basement membrane between the dermis and epidermis that serves to adhere the dermis and epidermis, provide mechanical support for the epidermis, and forms a barrier to cells and large molecules across the junction" [MP:0011159] synonym: "dermal-epidermal junction" EXACT [FMA:70963] synonym: "dermoepidermal junction" EXACT [FMA:70963] synonym: "dermo-epidermal junction" EXACT [] synonym: "epidermal dermol junction" EXACT [] is_a: UBERON:0005769 ! basement membrane relationship: part_of UBERON:0000014 {source="MP"} ! zone of skin relationship: adjacent_to UBERON:0002067 ! dermis relationship: adjacent_to UBERON:0001003 ! epidermis xref: FMA:70963 ! Dermal-epidermal junction xref: SCTID:51025007 ! Dermoepidermal junction [Term] id: UBERON:0008887 name: rectal venous plexus def: "The hemorrhoidal plexus (or rectal venous plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the uterovaginal plexus in the female. A free communication between the portal and systemic venous systems is established through the hemorrhoidal plexus." [Wikipedia:Rectal_venous_plexus] synonym: "hemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus] synonym: "haemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus] is_a: UBERON:0001593 {source="FMA"} ! venous plexus intersection_of: UBERON:0001593 ! venous plexus intersection_of: surrounds UBERON:0001052 ! rectum xref: FMA:18933 ! rectal venous plexus xref: ncithesaurus:Hemorrhoidal_Plexus ! Hemorrhoidal Plexus synonym: "plexus venosus rectalis, plexus haemorrhoidalis" RELATED LATIN [Wikipedia:Rectal_venous_plexus] xref: http://upload.wikimedia.org/wikipedia/commons/6/69/Gray587.png xref: SCTID:303051005 ! Entire hemorrhoidal plexus xref: UMLS:C0226766 [Term] id: UBERON:0008888 name: vesical venous plexus is_a: UBERON:0001593 {source="FMA"} ! venous plexus xref: FMA:18934 ! vesical venous plexus def: "The vesical plexus envelops the lower part of the bladder and the base of the prostate and communicates with the pudendal and prostatic plexuses. It is drained, by means of several vesical veins, into the hypogastric veins." [Wikipedia:Vesical_venous_plexus] xref: SCTID:31510008 ! Entire vesical venous plexus synonym: "plexus venosus vesicalis" RELATED LATIN [Wikipedia:Vesical_venous_plexus] xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png [Term] id: UBERON:0008889 name: uterine venous plexus def: "The uterine plexuses lie along the sides and superior angles of the uterus between the two layers of the broad ligament, and communicate with the ovarian and vaginal plexuses. They are drained by a pair of uterine veins on either side: these arise from the lower part of the plexuses, opposite the external orifice of the uterus, and open into the corresponding hypogastric vein." [Wikipedia:Uterine_venous_plexus] synonym: "uterine plexus" RELATED [Wikipedia:Uterine_venous_plexus] is_a: UBERON:0001593 {source="FMA"} ! venous plexus xref: FMA:29712 ! uterine venous plexus xref: SCTID:294553007 ! Entire uterine venous plexus synonym: "plexus venosus uterinus" RELATED LATIN [Wikipedia:Uterine_venous_plexus] xref: http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray589.png [Term] id: UBERON:0008904 name: neuromast def: "Volcano-shaped lateral line sensory organ located in characteristic positions within the skin epithelium and containing hair cells and their support elements. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.)" [ZFIN:ZDB-PUB-961014-576] synonym: "lateral line neuromast" EXACT [ZFA:0000243] synonym: "lateral line organ" EXACT [ZFA:0000243] synonym: "neuromasts" EXACT PLURAL [ZFA:0000243] xref: TAO:0000243 ! neuromast is_a: UBERON:0000477 {source="ZFA"} ! anatomical cluster relationship: part_of UBERON:0010202 ! lateral line xref: ZFA:0000243 ! neuromast xref: AAO:0001004 ! neuromast property_value: external_definition "Type of mechanoreceptive organ of the lateral line which are arranged in lines on the body surface. These organs are constituted by hair cells and supporting cells and it is located in the epidermis with its hair cells exposed to the surface. Absent in some caecilians. These receptors receive afferent and efferent innervations.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0001004", date_retrieved="2012-06-20", source="AAO:EJS"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass lateral line receptor (AAO:0010705)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0001004", date_retrieved="2012-06-20"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of lateral line receptor organ (AAO:0001001)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0001004", date_retrieved="2012-06-20"} property_value: external_definition "Volcano-shaped lateral line sensory organ located in characteristic positions within the skin epithelium and containing hair cells and their support elements. Kimmel et al, 1995. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.)[TAO]" xsd:string {ontology="TAO", external_class="TAO:0000243", date_retrieved="2012-08-14", source="ZFIN:curator"} synonym: "cyatocïde@fr" RELATED [TAO:0000243] synonym: "neuromaste superficiel@fr" RELATED [TAO:0000243] xref: EFO:0003513 ! neuromast [Term] id: UBERON:0008915 name: pore def: "An anatomical space that is an opening, usually at the end of a canal or duct, on the surface of the integument or the lining of an internal anatomical space." [TAO:curator] xref: TAO:0001791 ! pore is_a: UBERON:0000464 {source="ZFA"} ! anatomical space xref: ZFA:0005449 ! pore xref: AAO:0010441 ! pore xref: ncithesaurus:Pore xref: UMLS:C1325742 [Term] id: UBERON:0010521 name: electroreceptor organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0050964 ! detection of electrical stimulus involved in electroception relationship: only_in_taxon NCBITaxon:7742 {source="Wikipedia"} ! Vertebrata [Term] id: UBERON:0008917 name: ampullary organ def: "Organ that consists of receptor cells located within an epidermal invagination and functions as an electroreceptor." [TAO:wd] synonym: "ampullary electroreceptor organ" EXACT [TAO:0002104] is_a: UBERON:0003103 {source="TAO"} ! compound organ relationship: capable_of GO:0050964 ! detection of electrical stimulus involved in electroception relationship: part_of UBERON:0002540 ! lateral line system xref: TAO:0002104 ! ampullary organ xref: AAO:0001006 ! ampullary organ subset: organ_slim property_value: external_definition "An electroreceptor consisting of receptor cells sunk into the epidermis or located in an epidermal cavity opening to the surface through a duct and pore. It can detect weak electric currents generated by other animals.[AAO]" xsd:string {ontology="AAO", external_class="AAO:0001006", date_retrieved="2012-06-20", source="ZipcodeZoo:ampullary_organ"} property_value: axiom_lost_from_external_ontology "relationship loss: subclass lateral line receptor organ (AAO:0001001)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0001006", date_retrieved="2012-06-20"} property_value: axiom_lost_from_external_ontology "relationship loss: part_of lateral line receptor organ (AAO:0001001)[AAO]" xsd:string {ontology="AAO", external_class="AAO:0001006", date_retrieved="2012-06-20"} [Term] id: UBERON:0008918 name: ampulla of Lorenzini def: "The ampullae of Lorenzini are special sensing organs called electroreceptors, forming a network of jelly-filled pores... Each ampulla consists of a jelly-filled canal opening to the surface by a pore in the skin and ending blindly in a cluster of small pockets full of special jelly. The ampullae are mostly clustered into groups inside the body, each cluster having ampullae connecting with different parts of the skin, but preserving a left-right symmetry. The canal lengths vary from animal to animal, but the distribution of the pores is generally specific to each species. The ampullae pores are plainly visible as dark spots in the skin. They provide fish with a sixth sense capable of detecting electromagnetic fields as well as temperature gradients[WP]." [Wikipedia:Ampullae_of_Lorenzini] synonym: "ampullae of Lorenzini" EXACT PLURAL [Wikipedia:Ampullae_of_Lorenzini] is_a: UBERON:0003103 ! compound organ relationship: capable_of GO:0050964 ! detection of electrical stimulus involved in electroception relationship: part_of UBERON:0002540 ! lateral line system relationship: never_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: never_in_taxon NCBITaxon:32443 {source="Wikipedia"} ! Teleostei xref: http://upload.wikimedia.org/wikipedia/commons/8/88/Electroreceptors_in_a_sharks_head.svg subset: organ_slim [Term] id: UBERON:0008930 ! somatosensory cortex name: somatosensory cortex def: "Area of the parietal lobe concerned with receiving general sensations. It lies posterior to the central sulcus." [MESH:A08.186.211.730.885.213.670.675] comment: TODO - add layers synonym: "somesthetic area" RELATED [BTO:0004353] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0002581 {source="BTO"} ! postcentral gyrus xref: BTO:0004353 ! somatosensory cortex xref: MESH:A08.186.211.730.885.213.670.675 xref: GAID:681 ! somatosensory cortex xref: SCTID:279252006 ! Somesthetic area xref: EFO:0001391 ! somatosensory cortex [Term] id: UBERON:0008933 name: primary somatosensory cortex comment: ABA disjointness - Removed relationship: part_of UBERON:0001870 {source="MA"} ! frontal cortex is_a: UBERON:0008930 ! somatosensory cortex relationship: part_of UBERON:0001872 {source="MA"} ! parietal lobe xref: MA:0000908 ! primary somatosensory cortex [Term] id: UBERON:0008934 name: secondary somatosensory cortex comment: TODO - check brodmann is_a: UBERON:0008930 ! somatosensory cortex relationship: part_of UBERON:0001872 {source="MA"} ! parietal lobe xref: MA:0000918 ! secondary somatosensory cortex [Term] id: UBERON:0008935 name: albumen gland def: "The posterior oviduct opens into the large white albumen gland which adds a layer of albumen to the zygote before it reaches the egg capsule gland." [BTO:0000054] is_a: UBERON:0005398 {source="BTO"} ! female reproductive gland relationship: only_in_taxon NCBITaxon:6448 ! Gastropoda xref: BTO:0000054 ! albumen gland [Term] id: UBERON:0008936 name: gastropod genital pore def: "A small opening on the side of the head in some gastropods through which the penis is protruded." [BTO:0004684] synonym: "genital orifice" RELATED [BTO:0004684] synonym: "genital pore" EXACT [BTO:0004684] is_a: UBERON:0000161 ! orifice relationship: part_of UBERON:0000990 {source="BTO"} ! reproductive system relationship: only_in_taxon NCBITaxon:6448 ! Gastropoda xref: BTO:0004684 ! genital pore [Term] id: UBERON:0008937 name: visceral hump def: "Mollusks have three distinct divisions of their body. The head contains the sensory equipment (eyes, antennae, etc) and the primitive brain. The visceral hump, which is the main body, contains most of the organs, including a complete digestive and excretory tract as well as the reproductive organs. The visceral hump also includes the two external flaps of tissue, which are known as the mantle." [http://www.britannica.com/EBchecked/topic/630349/visceral-hump, BTO:0001448] is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:6447 ! Mollusca synonym: "visceral sac" RELATED [BTO:0001448] xref: BTO:0001448 ! visceral hump [Term] id: UBERON:0008939 name: pedal ganglion def: "The pedal ganglia mainly are necessary for coordination of locomotion of a snail." [BTO:0001012] is_a: UBERON:0000045 {source="BTO"} ! ganglion relationship: part_of UBERON:0008937 {source="BTO"} ! visceral hump relationship: only_in_taxon NCBITaxon:6447 ! Mollusca xref: BTO:0001012 ! pedal ganglion [Term] id: UBERON:0008940 name: parietal ganglion def: "The lateral ganglia of a snail nervous system are called parietal ganglia. They innerve pallial cavity, gills and skin." [BTO:0001841] is_a: UBERON:0000045 {source="BTO"} ! ganglion relationship: part_of UBERON:0008937 {source="BTO"} ! visceral hump relationship: only_in_taxon NCBITaxon:6447 ! Mollusca xref: BTO:0001841 ! parietal ganglion [Term] id: UBERON:0008941 name: pleural ganglion def: "The pallial cavity's nerve knots are called pleural ganglia. They innerve primarily the mantle or a snail." [BTO:0001842] is_a: UBERON:0000045 {source="BTO"} ! ganglion relationship: part_of UBERON:0008937 {source="BTO"} ! visceral hump relationship: only_in_taxon NCBITaxon:6447 ! Mollusca xref: BTO:0001842 ! pleural ganglion [Term] id: UBERON:0008942 name: gastropod cerebral ganglion def: "The cerebral ganglia are primarily sensual centres, that compute information from the eyes as well as from the tactile and position sensors (statocystes). Besides coordination they also serve the locational memory of a snail." [BTO:0001843] is_a: UBERON:0000045 {source="BTO"} ! ganglion xref: BTO:0001843 ! cerebral ganglion synonym: "cerebral ganglion" EXACT [BTO:0001843] [Term] id: UBERON:0008943 name: headfoot def: "The head-foot is the part you see most easily in slugs and snails. It is mostly a muscular organ covered in cilia and rich in mucous cells, which the mollusc uses to move around, it normally tapers to a tail at one end and has a head incorporated in the front. The head includes a mouth, eyes and tentacles, the last two may be much reduced or even absent. In those species with shells the head-foot can be drawn into the shell." [BTO:0003509] is_a: UBERON:0000475 ! organism subdivision xref: BTO:0003509 ! headfoot [Term] id: UBERON:0008944 name: albumen def: "Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo." [Wikipedia:Albumen, GO:0097099, https://sourceforge.net/tracker/index.php?func=detail&aid=3357613&group_id=36855&atid=440764] synonym: "egg white" EXACT [GO:0097099] is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0007379 ! egg xref: GO:0097099 ! structural constituent of albumen xref: ncithesaurus:Egg_White ! Egg White [Term] id: UBERON:0008964 ! abdominal ganglion of visceral hump name: abdominal ganglion of visceral hump def: "The visceral sacs nerve knot is called visceral ganglion. In contrary to the mostly paired other ganglia this nerve knot is unpaired. The visceral ganglion innerves the pallial organs as well as the inner organs." [BTO:0000022] is_a: UBERON:0000045 {source="BTO"} ! ganglion relationship: part_of UBERON:0008937 {source="BTO"} ! visceral hump relationship: only_in_taxon NCBITaxon:6447 ! Mollusca synonym: "visceral ganglion" RELATED [BTO:0000022] xref: BTO:0000022 ! abdominal ganglion synonym: "abdominal ganglion" RELATED [BTO:0000022] [Term] id: UBERON:0009758 name: abdominal ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk disjoint_from: UBERON:0008964 ! abdominal ganglion of visceral hump xref: SCTID:280508003 ! Abdominal ganglion def: "A ganglion that is part of a abdominal segment of trunk." [OBOL:automatic] [Term] id: UBERON:0008967 name: centrum semiovale def: "The semioval center is the white matter found underneath the grey matter on the surface of the cerebrum. The term is synonymous with cerebral white matter. The white matter, located in each hemisphere between the cerebral cortex and nuclei, as a whole has a semioval shape. It consists of cortical projection fibers, association fibers and cortical fibers." [Wikipedia:Semioval_center] comment: note that WP suggests a merge with cerebral white matter is_a: UBERON:0000073 ! regional part of nervous system relationship: part_of UBERON:0002437 {source="BTO"} ! cerebral white matter synonym: "semioval center" RELATED [BTO:0000229] synonym: "medullary center" EXACT [FMA:61939] synonym: "white matter of cerebrum" EXACT [FMA:61939] xref: SCTID:369198002 ! Entire centrum semiovale xref: BTO:0000229 ! centrum semiovale xref: FMA:61939 ! semioval center synonym: "centrum semiovale" RELATED LATIN [Wikipedia:Semioval_center] xref: http://upload.wikimedia.org/wikipedia/commons/9/95/Gray752.png [Term] id: UBERON:0008971 name: left colon def: "The distal portion of the colon; it develops embryonically from the hindgut and functions in the storage and elimination of waste." [BTO:0000646] is_a: UBERON:0000064 ! organ part relationship: develops_from UBERON:0001046 {source="BTO"} ! hindgut relationship: part_of UBERON:0001155 {source="BTO"} ! colon synonym: "distal colon" RELATED [BTO:0000646] xref: SCTID:362164005 ! Entire left colon xref: BTO:0000646 ! left colon xref: ncithesaurus:Left_Colon ! Left Colon xref: galen:LeftColon ! left colon xref: UMLS:C0227388 [Term] id: UBERON:0008972 name: right colon def: "The proximal portion of the colon, extending from the ileocecal valve usually to a point proximal to the left colic flexure; it develops embryonically from the terminal portion of the midgut and functions in absorption." [BTO:0000649] is_a: UBERON:0000064 ! organ part relationship: develops_from UBERON:0001045 {source="BTO"} ! midgut relationship: part_of UBERON:0001155 {source="BTO"} ! colon synonym: "proximal colon" RELATED [BTO:0000649] xref: SCTID:362161002 ! Entire right colon xref: BTO:0000649 ! right colon xref: ncithesaurus:Right_Colon ! Right Colon xref: galen:RightColon ! right colon xref: UMLS:C1305188 [Term] id: UBERON:0008975 name: shell gland def: "Any of various structures that secrete covering material for eggs or egg masses" [http://www.answers.com/topic/nidamental-gland] subset: grouping_class is_a: UBERON:0005398 {source="BTO"} ! female reproductive gland synonym: "nidamental gland" RELATED [] xref: SCTID:14478002 ! Shell gland xref: BTO:0001241 ! shell gland [Term] id: UBERON:0008977 name: pes anserinus of tibia def: "The pes anserinus is the insertion of the conjoined tendons of three muscles onto the anteromedial (front and inside) surface of the proximal extremity of the tibia." [Wikipedia:Pes_anserinus_%28leg%29] comment: Editors note: Consider adding muscle insertion site class synonym: "pes anserinus of leg" RELATED [Wikipedia:Pes_anserinus_%28leg%29] synonym: "pes anserine" RELATED [Wikipedia:Pes_anserinus_%28leg%29] synonym: "pes anserinus" EXACT [BTO:0001507] is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0000043 {source="BTO"} ! tendon relationship: has_muscle_insertion UBERON:0000979 ! tibia xref: SCTID:360767004 ! Pes anserinus xref: BTO:0001507 ! pes anserinus xref: http://upload.wikimedia.org/wikipedia/commons/b/b1/Pes_anserinus.png [Term] id: UBERON:0008979 name: carcass def: "A dead body." [BTO:0001965] is_a: UBERON:0000468 ! multi-cellular organism relationship: has_quality PATO:0001422 ! dead synonym: "cadaver" RELATED [BTO:0001965] synonym: "dead body" RELATED [BTO:0001965] xref: SCTID:127853004 ! Carcass xref: BTO:0001965 ! carcass [Term] id: UBERON:0008987 ! renal parenchyma name: renal parenchyma def: "The functional tissue of the kidney, consisting of the nephrons." [BTO:0003604] is_a: UBERON:0006554 {source="BTO"} ! urinary system structure synonym: "kidney parenchyma" RELATED [BTO:0003604] is_a: UBERON:0000353 {source="FMA"} ! parenchyma relationship: part_of UBERON:0002113 {source="FMA"} ! kidney intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002113 ! kidney xref: FMA:15574 ! parenchyma of kidney xref: SCTID:29704000 ! Structure of parenchyma of kidney xref: BTO:0003604 ! renal parenchyma synonym: "parenchyma of kidney" EXACT [FMA:15574] [Term] id: UBERON:0009883 name: medullary ray def: "A renal, cortical lobule, consisting of the ascending or descending limbs of the loop of Henle or of the collecting tubules; medullary rays are regions where parallel arrays of straight tubules travel perpendicular to the capsule and extend from the cortex to the medulla." [MP:0011347, Wikipedia:Bone_marrow_of_ovaryry_ray_(anatomy)] comment: Termonology notes: Their name is potentially misleading -- the "medullary" refers to their destination, not their location. They are located only in the renal cortex, and not in the renal medulla. AO notes: FMA says parenchyma, MP says cortex xref: FMA:74299 ! medullary ray xref: BTO:0001155 ! ray cell synonym: "Ferrein's pyramid" EXACT [MP:0011347] synonym: "kidney medullary ray" EXACT [MP:0011347] synonym: "renal medullary ray" EXACT [MP:0011347] is_a: UBERON:0000064 {source="FMA"} ! organ part relationship: part_of UBERON:0001225 {source="MP"} ! cortex of kidney relationship: overlaps UBERON:0001231 ! nephron tubule [Term] id: UBERON:0008989 name: esophageal gland def: "One of the racemose glands in the walls of the esophagus that in humans are small and serve principally to lubricate the food but in some birds secrete a milky fluid on which the young are fed." [BTO:0003634, Wikipedia:Esophageal_glands] synonym: "glandulae oesophageae" EXACT [Wikipedia:Esophageal_glands] synonym: "mucous gland of submucosa of esophagus" EXACT [FMA:9404] is_a: UBERON:0011148 ! submucosal gland relationship: secretes UBERON:0000912 ! mucus relationship: part_of UBERON:0001972 ! submucosa of esophagus relationship: part_of UBERON:0002330 ! exocrine system xref: SCTID:322749003 ! Entire esophageal gland xref: BTO:0003634 ! esophageal gland xref: FMA:9404 ! Esophageal gland xref: ncithesaurus:Esophageal_Gland ! Esophageal Gland xref: http://upload.wikimedia.org/wikipedia/commons/e/e8/Illu_esophageal_layers.jpg xref: UMLS:C0227178 [Term] id: UBERON:0008992 name: chorion frondosum def: "The part of the chorion where the villi persist, forming the foetal part of the placenta." [BTO:0003677] is_a: UBERON:0000478 {source="BTO"} ! extraembryonic structure relationship: part_of UBERON:0003124 {source="BTO"} ! chorion synonym: "shaggy chorion" RELATED [BTO:0003677] xref: SCTID:37333001 ! Structure of chorion frondosum xref: BTO:0003677 ! chorion frondosum [Term] id: UBERON:0008993 name: habenular nucleus def: "The gray matter of the habenula, composed of a small-celled medial and a larger-celled lateral habenular nucleus; both nuclei receive fibres from basal forebrain regions (septum, basal nucleus, lateral preoptic nucleus); the lateral habenular nucleus receives an additional projection from the medial segment of the globus pallidus. Both nuclei project by way of the retroflex fasciculus to the interpeduncular nucleus and a medial zone of the midbrain tegmentum." [BTO:0003685] is_a: UBERON:0000445 {source="BTO"} ! habenular trigone relationship: part_of UBERON:0001904 {source="BTO"} ! habenula synonym: "ganglion habenulae" RELATED [BTO:0003685] synonym: "nucleus habenulae" RELATED [BTO:0003685] xref: SCTID:279303009 ! Habenular nucleus xref: BTO:0003685 ! habenular nucleus xref: EHDAA2:0004710 ! habenular nucleus [Term] id: UBERON:0008995 name: nucleus of cerebellar nuclear complex def: "Four accumulations of gray substance embedded in the white substance of the cerebellum, comprising the nucleus dentatus, nucleus emboliformis, nucleus globosus, and nucleus fastigii." [BTO:0003835] synonym: "cerebellar nucleus" EXACT [BTO:0003835] synonym: "deep cerebellar nucleus" EXACT [] intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002130 ! cerebellar nuclear complex xref: SCTID:279220006 ! Cerebellar nucleus xref: BTO:0003835 ! cerebellar nucleus xref: MA:0000203 ! deep cerebellar nucleus [Term] id: UBERON:0002132 alt_id: UBERON:0008996 name: dentate nucleus def: "The Dentate nucleus is located within the deep white matter of each cerebellar hemisphere. It is the largest of the four deep cerebellar nuclei, the others being the fastigial nucleus and the interposed nucleus (globose and emboliform nuclei combined). It is responsible for the planning, initiation and control of volitional movements. It therefore receives its afferents from the premotor cortex and the supplementary motor cortex. Its efferents project via the superior cerebellar peduncle through the red nucleus to the ventrolateral thalamus (crossing over at the pontomesencephalic junction). It consists of an irregularly folded, of a grayish-yellow color, containing white fibers, and presenting on its antero-medial aspect an opening, the hilus, from which most of the fibers of the superior peduncle emerge. [WP,unvetted]." [Wikipedia:Dentate_nucleus] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "dentatothalamocortical fibers" RELATED [Wikipedia:Dentate_nucleus] synonym: "nucleus dentatus" RELATED [Wikipedia:Dentate_nucleus] synonym: "dentate nucleus" RELATED [Wikipedia:Dentate_nucleus] synonym: "lateral cerebellar nucleus" EXACT [] synonym: "lateral nucleus of cerebellum" EXACT [] synonym: "dentate cerebellar nucleus" EXACT [NIF_GrossAnatomy:birnlex_1171] xref: FMA:72260 ! Dentate nucleus xref: MA:0001008 ! lateral cerebellar nucleus xref: NIF_GrossAnatomy:birnlex_1171 ! Dentate nucleus xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/23/Gray707.png/200px-Gray707.png xref: EV:0100300 ! dentate nucleus xref: ABA:DN ! Dentate nucleus xref: BM:CB-CBL ! lateral nucleus of cerebellum xref: SCTID:279221005 ! Nucleus dentatus xref: BTO:0003836 ! nucleus dentatus is_a: UBERON:0002308 ! nucleus of brain relationship: part_of UBERON:0002130 ! cerebellar nuclear complex relationship: spatially_disjoint_from UBERON:0002153 {source="ABA"} ! fastigial nucleus synonym: "nucleus dentatus" RELATED LATIN [Wikipedia:Dentate_nucleus] xref: http://upload.wikimedia.org/wikipedia/commons/2/23/Gray707.png xref: VHOG:0001700 ! dentate nucleus property_value: homology_notes "One or more deep cerebellar nuclei appear in agnathans, sharks, ropefishes, lungfishes, Latimeria, and amphibians. Reptiles have two nuclei (a medial and a lateral), and birds and mammals have three nuclei (a medial, a lateral, and an interposed nucleus). The medial nucleus of mammals is known as the fastigial nucleus, and the lateral nucleus is known as the dentate nucleus.[well established][VHOG]" xsd:string {external_class="VHOG:0001700", ontology="VHOG", source="ISBN:978-0471210054 Butler AB\, Hodos W\, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.260-261", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} [Term] id: UBERON:0008998 name: cerebrovascular system def: "System pertaining to blood vessels in the brain." [BTO:0003840] is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0007798 {source="BTO"} ! vascular system xref: SCTID:362029003 ! Entire cerebrovascular system xref: BTO:0003840 ! cerebrovascular system [Term] id: UBERON:0008999 name: hoof lamina def: "The tissues which attach the third phalanx to the hoof wall." [BTO:0003997] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0008963 {source="BTO"} ! hoof synonym: "hoof laminae" RELATED [BTO:0003997] xref: SCTID:370743008 ! Laminae of hoof xref: BTO:0003997 ! hoof lamina [Term] id: UBERON:0009000 name: ischial spine def: "A bony process projecting backward and medialward from the posterior border of the ischium." [BTO:0004149] is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0001130 {source="BTO"} ! vertebral column xref: SCTID:18074002 ! Structure of ischial spine xref: BTO:0004149 ! ischial spine xref: FMA:17028 ! Ischial spine synonym: "spina ischialis" EXACT [FMA:17028] [Term] id: UBERON:0009002 name: placental membrane def: "The membrane separating the fetal from the maternal blood in the placenta; sometimes inappropriately called the placental barrier." [BTO:0004196] is_a: UBERON:0000478 {source="BTO"} ! extraembryonic structure relationship: part_of UBERON:0001987 {source="BTO"} ! placenta synonym: "placental barrier" RELATED [BTO:0004196] xref: SCTID:256591004 ! Entire placental membrane xref: BTO:0004196 ! placental membrane xref: ncithesaurus:Placental_Membrane ! Placental Membrane xref: UMLS:C0230984 [Term] id: UBERON:0009006 name: deep inguinal lymph node def: "One of several small inconstant lymph nodes, proximal, intermediate and distal deep to the fascia lata and medial to the femoral vein; they receive lymph from the deep structures of the lower limb, from the glans penis and from superficial inguinal nodes; efferents pass to the external iliac nodes." [BTO:0004548] is_a: UBERON:0000029 {source="BTO"} ! lymph node synonym: "nodi lymphatici inguinales profundi" RELATED [BTO:0004548] xref: SCTID:65266007 ! Structure of deep inguinal lymph node xref: BTO:0004548 ! deep inguinal lymph node xref: FMA:44225 ! Deep inguinal lymph node synonym: "deep inguinal node" EXACT [FMA:44225] synonym: "nodus lymphaticus inguinalis profundus" EXACT [FMA:44225] [Term] id: UBERON:0009007 name: superficial inguinal lymph node def: "A group of 12-20 lymph nodes that lie in the subcutaneous tissue below the inguinal ligament and along the terminal part of the great saphenous vein; they drain the skin and subcutaneous tissue of the lower abdominal wall, perineum, buttocks, external genitalia, and lower limbs." [BTO:0004549] is_a: UBERON:0000029 {source="BTO"} ! lymph node xref: SCTID:113340006 ! Structure of superficial inguinal lymph node xref: BTO:0004549 ! superficial inguinal lymph node xref: FMA:5036 ! Superficial inguinal lymph node synonym: "lymph node of cloquet" EXACT [FMA:5036] synonym: "lymph node of rosenmuller" EXACT [FMA:5036] synonym: "nodus lymphaticus inguinalis superficialis" EXACT [FMA:5036] synonym: "superficial inguinal node" EXACT [FMA:5036] [Term] id: UBERON:0009009 name: carotid sinus nerve def: "Carotid branch of glossopharyngeal nerve." [BTO:0004978] is_a: UBERON:0001021 {source="FMA"} ! nerve relationship: part_of UBERON:0001649 {source="BTO"} ! glossopharyngeal nerve xref: SCTID:50624003 ! Carotid sinus nerve xref: BTO:0004978 ! carotid sinus nerve xref: FMA:53488 ! Carotid sinus nerve synonym: "carotid branch of glossopharyngeal nerve" EXACT [FMA:53488] synonym: "ramus sinus carotici" EXACT [FMA:53488] [Term] id: UBERON:0009010 name: periurethral tissue def: "Tissue around the urethra." [BTO:0005081] is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0000057 ! urethra xref: SCTID:256880003 ! Entire periurethral tissue xref: BTO:0005081 ! periurethral tissue [Term] id: UBERON:0009014 name: lower back skin is_a: UBERON:0003836 {source="MA"} ! abdominal segment skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0005462 ! lower back xref: SCTID:286601005 ! Entire skin of lower back xref: MA:0000504 ! lower back skin subset: organ_slim def: "A zone of skin that is part of a lower back." [OBOL:automatic] [Term] id: UBERON:0009015 name: upper back skin is_a: UBERON:0001418 {source="MA"} ! skin of thorax intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0008231 ! dorsal thoracic segment of trunk xref: SCTID:304890003 ! Entire skin of upper back xref: MA:0000510 ! upper back skin def: "A zone of skin that is part of a dorsal thoracic segment of trunk." [OBOL:automatic] [Term] id: UBERON:0009016 name: ciliary stroma synonym: "ocular ciliary stroma" EXACT [] synonym: "stroma of ciliary body" EXACT [] is_a: UBERON:0003891 ! stroma relationship: part_of UBERON:0001775 {source="MA"} ! ciliary body xref: SCTID:280868008 ! Ciliary stroma xref: MA:0001239 ! ciliary stroma xref: SCTID:280868008 ! Ciliary stroma [Term] id: UBERON:0009020 name: left uterine horn intersection_of: UBERON:0002247 ! uterine horn intersection_of: in_left_side_of UBERON:0000995 ! uterus xref: SCTID:245482004 ! Entire left horn of uterus xref: MA:0001727 ! left uterine horn def: "An uterine horn that is in the left side of a uterus." [OBOL:automatic] [Term] id: UBERON:0009022 name: right uterine horn intersection_of: UBERON:0002247 ! uterine horn intersection_of: in_right_side_of UBERON:0000995 ! uterus xref: SCTID:245481006 ! Entire right horn of uterus xref: MA:0001728 ! right uterine horn def: "An uterine horn that is in the right side of a uterus." [OBOL:automatic] [Term] id: UBERON:0009024 name: adrenal gland X zone def: "A wide juxta-medullary layer of cells in the adrenal glands of young mature virgin female mice." [http://www.jstor.org/pss/82802] is_a: UBERON:0009753 {source="MA"} ! adrenal gland cortex zone relationship: part_of UBERON:0001235 {source="MA"} ! adrenal cortex relationship: part_of UBERON:0003100 ! female organism relationship: only_in_taxon NCBITaxon:10088 ! Mus synonym: "juvenile zone" RELATED [MA:0001888] xref: SCTID:24306004 ! X-zone of adrenal gland xref: MA:0001888 ! adrenal gland X zone [Term] id: UBERON:0009025 name: gastroepiploic artery def: "Abdominal artery that follows the curvature of the stomach. The right gasteroepiploic artery is frequently used in coronary artery bypass grafting, myocardial revascularization, and other vascular reconstruction." [MESH:A07.231.114.379] subset: grouping_class xref: MESH:A07.231.114.379 is_a: UBERON:0001637 {source="MA"} ! artery xref: SCTID:261401008 ! Gastroepiploic artery xref: MA:0001962 ! gastroepiploic artery xref: ncithesaurus:Gastroepiploic_Artery ! Gastroepiploic Artery xref: UMLS:C0447070 [Term] id: UBERON:0009026 ! iliac circumflex artery name: iliac circumflex artery is_a: UBERON:0001637 {source="MA"} ! artery xref: SCTID:244327004 ! Circumflex iliac artery xref: MA:0001975 ! iliac circumflex artery xref: ncithesaurus:Circumflex_Iliac_Artery ! Circumflex Iliac Artery xref: UMLS:C0447101 [Term] id: UBERON:0009040 name: deep circumflex iliac artery def: "The deep circumflex iliac artery (or deep iliac circumflex artery) is an artery in the pelvis that travels along the iliac crest of the pelvic bone." [Wikipedia:Deep_circumflex_iliac_artery] synonym: "deep iliac circumflex" RELATED [Wikipedia:Deep_circumflex_iliac_artery] synonym: "deep iliac circumflex artery" RELATED [Wikipedia:Deep_circumflex_iliac_artery] synonym: "arteria circumflexa ilium profunda" EXACT [Wikipedia:Deep_circumflex_iliac_artery] is_a: UBERON:0009026 ! iliac circumflex artery relationship: branch_of UBERON:0001308 {source="FMA"} ! external iliac artery relationship: part_of UBERON:0001308 {source="FMA"} ! external iliac artery xref: FMA:20687 ! deep circumflex iliac artery xref: http://upload.wikimedia.org/wikipedia/commons/0/07/Gray586.png xref: ncithesaurus:Deep_Circumflex_Iliac_Artery ! Deep Circumflex Iliac Artery synonym: "arteria circumflexa ilium profunda" RELATED LATIN [Wikipedia:Deep_circumflex_iliac_artery] xref: http://upload.wikimedia.org/wikipedia/commons/7/74/Gray586.png xref: SCTID:181353005 ! Entire deep circumflex iliac artery xref: UMLS:C0226405 [Term] id: UBERON:0009041 name: superficial circumflex iliac artery def: "The superficial iliac circumflex artery (or superficial circumflex iliac), the smallest of the cutaneous branches of the femoral artery, arises close to the superficial epigastric artery, and, piercing the fascia lata, runs lateralward, parallel with the inguinal ligament, as far as the crest of the ilium. It divides into branches which supply the integument of the groin, the superficial fascia, and the superficial subinguinal lymph glands, anastomosing with the deep iliac circumflex, the superior gluteal and lateral femoral circumflex arteries." [Wikipedia:Superficial_circumflex_iliac_artery] synonym: "iliac circumflex artery" RELATED [Wikipedia:Superficial_iliac_circumflex_artery] synonym: "superficial circumflex iliac artery" RELATED [Wikipedia:Superficial_iliac_circumflex_artery] synonym: "arteria circumflexa ilium superficialis" EXACT [Wikipedia:Superficial_iliac_circumflex_artery] is_a: UBERON:0009026 ! iliac circumflex artery relationship: branch_of UBERON:0002060 {source="FMA"} ! femoral artery relationship: part_of UBERON:0001308 {source="FMA"} ! external iliac artery relationship: part_of UBERON:0002060 {source="FMA"} ! femoral artery xref: FMA:20737 ! superficial circumflex iliac artery xref: http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray548.png xref: ncithesaurus:Superficial_Circumflex_Iliac_Artery ! Superficial Circumflex Iliac Artery xref: UMLS:C0738891 [Term] id: UBERON:0009042 name: prostatic venous plexus def: "The prostatic veins form a well-marked prostatic plexus which lies partly in the fascial sheath of the prostate and partly between the sheath and the prostatic capsule. It communicates with the pudendal and vesical plexuses." [Wikipedia:Prostatic_venous_plexus] synonym: "pudendal venous plexus" RELATED [FMA:29711] is_a: UBERON:0001593 {source="FMA"} ! venous plexus xref: FMA:29711 ! prostatic venous plexus synonym: "plexus venosus prostaticus" RELATED LATIN [Wikipedia:Prostatic_venous_plexus] xref: http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png xref: SCTID:303052003 ! Entire prostatic venous plexus [Term] id: UBERON:0009044 name: pudendal venous plexus def: "The pudendal plexus (vesicoprostatic plexus) lies behind the arcuate pubic ligament and the lower part of the pubic symphysis, and in front of the bladder and prostate. Its chief tributary is the deep dorsal vein of the penis, but it also receives branches from the front of the bladder and prostate. It communicates with the vesical plexus and with the internal pudendal vein and drains into the vesical and hypogastric veins." [Wikipedia:Pudendal_plexus_(veins)] is_a: UBERON:0001593 ! venous plexus xref: SCTID:65326006 ! Entire pudendal venous plexus [Term] id: UBERON:0009029 name: pudendal vein is_a: UBERON:0001638 {source="MA"} ! vein xref: SCTID:395225000 ! Pudendal vein xref: MA:0002202 ! pudendal vein [Term] id: UBERON:0009048 name: deep external pudendal vein is_a: UBERON:0009029 ! pudendal vein xref: FMA:44488 ! deep external pudendal vein [Term] id: UBERON:0009049 name: superficial external pudendal vein is_a: UBERON:0009029 ! pudendal vein xref: FMA:21377 ! superficial external pudendal vein [Term] id: UBERON:0009046 name: inferior external pudendal vein is_a: UBERON:0009029 {source="MA"} ! pudendal vein xref: MA:0002203 ! inferior external pudendal vein [Term] id: UBERON:0009047 name: superior external pudendal vein is_a: UBERON:0009029 {source="MA"} ! pudendal vein xref: MA:0002204 ! superior external pudendal vein [Term] id: UBERON:0009030 name: left pulmonary vein is_a: UBERON:0002016 {source="MA"} ! pulmonary vein xref: SCTID:304057004 ! Entire left pulmonary vein xref: MA:0002207 ! left pulmonary vein xref: ncithesaurus:Left_Pulmonary_Vein ! Left Pulmonary Vein xref: UMLS:C0226670 [Term] id: UBERON:0009032 name: right pulmonary vein is_a: UBERON:0002016 {source="MA"} ! pulmonary vein xref: SCTID:304056008 ! Entire right pulmonary vein xref: MA:0002208 ! right pulmonary vein xref: ncithesaurus:Right_Pulmonary_Vein ! Right Pulmonary Vein xref: UMLS:C0226669 [Term] id: UBERON:0009034 name: stomach region intersection_of: UBERON:0000064 ! organ part intersection_of: part_of UBERON:0000945 ! stomach xref: SCTID:245415005 ! Region of stomach (also: UBERON:0009870 'zone of stomach') xref: MA:0002561 ! stomach region def: "An organ part that is part of a stomach." [OBOL:automatic] [Term] id: UBERON:0009035 name: renal straight tubule comment: todo - add relationships is_a: UBERON:0001231 {source="MA"} ! nephron tubule xref: SCTID:245151008 ! Entire straight renal tubule xref: MA:0002634 ! renal straight tubule synonym: "kidney straight tubule" EXACT [MA:0002634] [Term] id: UBERON:0009038 name: sulcus ampullaris def: "the groove on the external surface of the ampulla of each semicircular duct where the nerve enters the ampullary crest." [http://www.medilexicon.com/medicaldictionary.php?s=ampullary+groove] synonym: "ampullary groove" EXACT [FMA:74584] synonym: "ampullary sulcus" EXACT [] is_a: UBERON:0006800 {source="FMA"} ! anatomical line relationship: part_of UBERON:0004043 {source="MA"} ! semicircular canal ampulla xref: SCTID:368954006 ! Entire sulcus ampullaris xref: MA:0002835 ! sulcus ampullaris xref: FMA:74584 ! ampullary groove [Term] id: UBERON:0009089 name: inner medulla vasa recta descending limb comment: This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the inner medullar parallel to the descending limb is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0004776 {source="KUPO"} ! inner renal medulla vasa recta xref: KUPO:0001003 ! inner medulla vasa recta descending limb [Term] id: UBERON:0009090 name: outer medulla vasa recta descending limb comment: This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the outer medullar parallel to the descending limb is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0004775 {source="KUPO"} ! outer renal medulla vasa recta xref: KUPO:0001004 ! outer medulla vasa recta descending limb [Term] id: UBERON:0009202 name: vasa recta descending limb comment: This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta parallel to the descending limb is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0004726 {source="KUPO"} ! vasa recta xref: KUPO:0001002 ! vasa recta descending limb [Term] id: UBERON:0009091 name: vasa recta ascending limb comment: This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta parallel to the ascending limb is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0004726 {source="KUPO"} ! vasa recta xref: KUPO:0001005 ! vasa recta ascending limb [Term] id: UBERON:0009092 name: inner medulla vasa recta ascending limb comment: This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the inner medulla parallel to the ascending limb is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0004776 {source="KUPO"} ! inner renal medulla vasa recta xref: KUPO:0001006 ! inner medulla vasa recta ascending limb [Term] id: UBERON:0009093 name: outer medulla vasa recta ascending limb comment: This class was created in order to align KUPO with CL. The original class was undefined, and the intended meaning is not clear, may be obsoleted in future. The vasa recta is parallel to the loop of Henles, this may refer to the portion of the vasa recta in the outer medulla parallel to the ascending limb is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0004775 {source="KUPO"} ! outer renal medulla vasa recta xref: KUPO:0001007 ! outer medulla vasa recta ascending limb [Term] id: UBERON:0009095 name: tip of renal papilla is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001228 {source="KUPO"} ! renal papilla xref: KUPO:0001009 ! papillary tips synonym: "papillary tip" EXACT [KUPO:0001009] synonym: "papillary tips" EXACT PLURAL [KUPO:0001009] [Term] id: UBERON:0013237 name: genital papilla of vulva def: "The genital papilla is a part of female external genitalia not present in humans, which appears as a small, fleshy flab of tissue. The papilla covers the opening of the vagina." [Wikipedia:Genital_papilla] synonym: "genital papillae" RELATED PLURAL [] synonym: "mammalian genital papilla" EXACT [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0000997 ! mammalian vulva [Term] id: UBERON:0009129 name: right atrium endocardium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002078 ! right atrium is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium relationship: develops_from UBERON:0005092 {source="EHDAA2"} ! right horn of sinus venosus relationship: part_of UBERON:0006218 {source="EHDAA2"} ! common atrial chamber xref: SCTID:3194006 ! Endocardium of right atrium xref: EHDAA2:0000274 ! right atrium endocardium xref: FMA:7281 ! Endocardium of right atrium synonym: "endocardium of right atrium" EXACT [FMA:7281] xref: VHOG:0001228 ! right atrium endocardium synonym: "right atrial endocardium" EXACT [FMA:7281] synonym: "right atrium endocardial tissue" RELATED [VHOG:0001228] def: "An endocardium that is part of a right atrium." [OBOL:automatic] [Term] id: UBERON:0009130 name: dorsal meso-duodenum is_a: UBERON:0002050 {source="EHDAA2"} ! embryonic structure relationship: part_of UBERON:0005712 {source="EHDAA2"} ! midgut duodenum mesentery xref: SCTID:361433003 ! Dorsal mesoduodenum xref: RETIRED_EHDAA2:0000411 ! dorsal meso-duodenum [Term] id: UBERON:0009133 name: pleuroperitoneal membrane alt_id: UBERON:0009146 def: "A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities." [http://medical-dictionary.thefreedictionary.com/pleuroperitoneal+membrane, Wikipedia:Pleuroperitoneal] is_a: UBERON:0002050 {source="EHDAA2"} ! embryonic structure is_a: UBERON:0000479 {source="EHDAA2"} ! tissue relationship: adjacent_to UBERON:0001179 ! peritoneal cavity relationship: adjacent_to UBERON:0002402 ! pleural cavity synonym: "pleuroperitoneal membranes" EXACT PLURAL [EHDAA2:0001483] xref: EMAPA:17709 ! pleuro-peritoneal membrane xref: SCTID:361429005 ! Pleuroperitoneal membrane xref: EHDAA2:0001483 ! pleuroperitoneal membranes xref: ncithesaurus:Pleuroperitoneal_Membrane ! Pleuroperitoneal Membrane xref: VHOG:0000757 ! pleuroperitoneal fold synonym: "pleuroperitoneal fold" EXACT [VHOG:0000757] property_value: homology_notes "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {external_class="VHOG:0000757", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M\, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1283968 [Term] id: UBERON:0009141 name: craniocervical region vein synonym: "head and neck veins" EXACT [EHDAA2:0004542] synonym: "vein of head and neck" EXACT [] synonym: "craniocervical vein" EXACT [] intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0004581 {source="EHDAA2"} ! systemic venous system xref: SCTID:32945007 ! Vein of head and neck xref: EHDAA2:0004542 ! head and neck veins def: "A vein that is part of a craniocervical region." [OBOL:automatic] [Term] id: UBERON:0009149 name: foramen primum def: "opening in the septum primum between the two atria of the embryonic heart[TMD]." [http://medical-dictionary.thefreedictionary.com/foramen+primum, Wikipedia:Primary_interatrial_foramen] synonym: "ostium primum" EXACT [http://medical-dictionary.thefreedictionary.com/foramen+primum] synonym: "primary interatrial foramen" EXACT [Wikipedia:Primary_interatrial_foramen] synonym: "interatrial foramen primum" EXACT [Wikipedia:Primary_interatrial_foramen] is_a: UBERON:0004111 {source="EHDAA2"} ! anatomical conduit relationship: part_of UBERON:0004154 {source="EHDAA2"} ! septum primum relationship: part_of UBERON:0002085 {source="EHDAA2"} ! interatrial septum xref: EMAPA:17012 ! foramen primum xref: EHDAA2:0001826 ! foramen primum xref: SCTID:308852002 ! ostium primum xref: ncithesaurus:Foramen_Primum ! Foramen Primum xref: VHOG:0001470 ! foramen primum property_value: external_definition "First of the two openings to perforate the septum primum between the two atria of the embryonic heart. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001470", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/foramen", source="http://bgee.unil.ch/"} property_value: homology_notes "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether. [ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620]; [about heart development] In the various tetrapod classes ontogenetic events essentially recapitulate the phylogenetic stages.[well established][VHOG]" xsd:string {external_class="VHOG:0001470", ontology="VHOG", source="ISBN:978-0721676678 p.433", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1517292 [Term] id: UBERON:0006678 name: foramen secundum def: "a foramen in the septum primum." [Wikipedia:Foramen_secundum] xref: FMA:71105 ! Foramen secundum xref: EMAPA:17863 ! foramen secundum xref: EHDAA2:0001828 ! septum secundum foramen xref: VHOG:0001471 ! foramen secundum is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004154 {source="EHDAA2"} ! septum primum xref: ncithesaurus:Foramen_Secundum ! Foramen Secundum xref: SCTID:308854001 ! ostium secundum synonym: "ostium secundum" EXACT [SCTID:308854001] disjoint_from: UBERON:0004754 ! foramen ovale of heart synonym: "foramen secundum" RELATED LATIN [Wikipedia:Foramen_secundum] property_value: external_definition "Second of the two openings to perforate the septum primum between the two atria of the embryonic heart. [TFD][VHOG]" xsd:string {ontology="VHOG", external_class="VHOG:0001471", date_retrieved="2012-09-17", source="http://medical-dictionary.thefreedictionary.com/foramen", source="http://bgee.unil.ch/"} property_value: homology_notes "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether. [ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620]; [about heart development] In the various tetrapod classes ontogenetic events essentially recapitulate the phylogenetic stages.[well established][VHOG]" xsd:string {external_class="VHOG:0001471", ontology="VHOG", source="ISBN:978-0721676678 p.433", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} xref: UMLS:C1517293 [Term] id: UBERON:0009191 ! sphenoid bone pre-cartilage condensation name: sphenoid bone pre-cartilage condensation is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: part_of UBERON:0001703 {source="EHDAA2"} ! neurocranium relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium xref: EMAPA:18015 ! sphenoid bone pre-cartilage condensation xref: EHDAA2:0003446 ! sphenoid bone pre-cartilage condensation [Term] id: UBERON:0009192 name: basisphenoid pre-cartilage condensation synonym: "basi-sphenoid pre-cartilage condensation" EXACT [EHDAA2:0003447] is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: develops_from UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! mesenchyme derived from head mesoderm relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium xref: EMAPA:18013 ! basisphenoid pre-cartilage condensation xref: EHDAA2:0003447 ! basi-sphenoid pre-cartilage condensation [Term] id: UBERON:0009193 ! sphenoid bone cartilage condensation name: sphenoid bone cartilage condensation is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium relationship: develops_from UBERON:0009191 ! sphenoid bone pre-cartilage condensation xref: EHDAA2:0001888 ! sphenoid bone cartilage condensation [Term] id: UBERON:0009194 ! basisphenoid cartilage condenstion name: basisphenoid cartilage condenstion is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation relationship: develops_from UBERON:0009192 {source="EHDAA2"} ! basisphenoid pre-cartilage condensation relationship: part_of UBERON:0009193 {source="EHDAA2"} ! sphenoid bone cartilage condensation xref: EHDAA2:0000166 ! basisphenoid cartilage condenstion xref: VHOG:0001338 ! basisphenoid cartilage condensation synonym: "basisphenoid cartilage condensation" EXACT [VHOG:0001338] [Term] id: UBERON:0009197 name: basioccipital pre-cartilage condensation is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation relationship: part_of UBERON:0002241 {source="EMAPA"} ! chondrocranium relationship: develops_into UBERON:0001692 {source="EHDAA2"} ! basioccipital bone xref: EMAPA:18012 ! basioccipital pre-cartilage condensation xref: EHDAA2:0000165 ! basioccipital pre-cartilage condensation xref: VHOG:0000959 ! basioccipital pre-cartilage condensation xref: EHDAA:6033 ! basioccipital pre-cartilage condensation [Term] id: UBERON:0009468 name: basiotic bone def: "a small bone in the fetus between the basilar process and the basisphenoid." [http://medical-dictionary.thefreedictionary.com/basiotic+bone] synonym: "basiotic" EXACT [] xref: SCTID:95946002 ! basiotic bone is_a: UBERON:0011164 ! neurocranium bone relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0009472 name: axilla def: "The axilla is the area on the human body directly under the joint where the arm connects to the shoulder." [Wikipedia:Axilla] synonym: "axillary region" EXACT [FMA:24864] synonym: "regio axillaris" EXACT LATIN [FMA:TA] synonym: "arm pit" EXACT [Wikipedia:Axilla] synonym: "armpit" EXACT [Wikipedia:Axilla] synonym: "armpits" RELATED [Wikipedia:Axilla] synonym: "axillae" RELATED [Wikipedia:Axilla] synonym: "axillary region" RELATED [Wikipedia:Axilla] synonym: "oxter" RELATED [Wikipedia:Axilla] synonym: "underarm" RELATED [Wikipedia:Axilla] is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0001421 {source="FMA"} ! pectoral girdle region xref: FMA:24864 ! axilla xref: MESH:A01.378.800.090 xref: ncithesaurus:Axilla ! Axilla synonym: "axilla" RELATED LATIN [Wikipedia:Axilla] xref: http://upload.wikimedia.org/wikipedia/commons/f/f2/Gray411.png xref: SCTID:362732006 ! Entire axillary region xref: galen:Axilla ! axilla xref: EFO:0001395 ! axilla property_value: has_relational_adjective "axillary" xsd:string xref: UMLS:C0004454 [Term] id: UBERON:0009478 name: associated mesenchyme of midgut subset: emapa_ehdaa2 comment: Editors note: previously logically defined as mesenchyme of midgut, but this caused disjointness violations between dense and loose mesenchyme synonym: "early midgut associated mesenchyme" EXACT [EHDAA2:0001186] is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: part_of UBERON:0001045 ! midgut relationship: develops_from UBERON:0010378 {source="EHDAA2"} ! mesenchyme from splanchnopleure xref: EHDAA2:0001186 ! early midgut associated mesenchyme xref: EMAPA:16256 ! associated mesenchyme of midgut def: "Mesenchyme that is part of a midgut." [OBOL:automatic] [Term] id: UBERON:0010327 name: obsolete early digestive tract associated mesenchyme is_obsolete: true [Term] id: UBERON:0009479 name: ectoderm of buccopharyngeal membrane subset: emapa_ehdaa2 intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0006211 ! buccopharyngeal membrane xref: EHDAA2:0000190 ! buccopharyngeal membrane ectoderm xref: EMAPA:16260 ! ectoderm of buccopharyngeal membrane def: "An ectoderm that is part of a buccopharyngeal membrane." [OBOL:automatic] [Term] id: UBERON:0009480 name: endoderm of buccopharyngeal membrane subset: emapa_ehdaa2 intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0006211 ! buccopharyngeal membrane xref: EHDAA2:0000191 ! buccopharyngeal membrane endoderm xref: EMAPA:16261 ! endoderm of buccopharyngeal membrane def: "An endoderm that is part of a buccopharyngeal membrane." [OBOL:automatic] [Term] id: UBERON:0009481 name: cavity of pericardio-peritoneal canal subset: emapa_ehdaa2 intersection_of: UBERON:0005082 ! tube lumen intersection_of: part_of UBERON:0006275 ! pericardio-peritoneal canal xref: EHDAA2:0001441 ! pericardio-peritoneal canal cavity xref: EMAPA:16283 ! cavity of pericardio-peritoneal canal xref: VHOG:0000564 ! cavity of the pericardio-peritoneal canal synonym: "cavity of the pericardio-peritoneal canal" EXACT [VHOG:0000564] def: "A tube lumen that is part of a pericardio-peritoneal canal." [OBOL:automatic] [Term] id: UBERON:0009482 name: associated mesenchyme of foregut-midgut junction subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006235 ! foregut-midgut junction xref: EHDAA2:0000570 ! foregut-midgut junction associated mesenchyme xref: EMAPA:16364 ! associated mesenchyme of foregut-midgut junction def: "Mesenchyme that is part of a foregut-midgut junction." [OBOL:automatic] [Term] id: UBERON:0009483 ! mesentery of foregut-midgut junction name: mesentery of foregut-midgut junction subset: emapa_ehdaa2 intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0006235 ! foregut-midgut junction xref: EHDAA2:0000575 ! foregut-midgut junction mesentery xref: EMAPA:16365 ! mesentery of foregut-midgut junction xref: VHOG:0000430 ! foregut-midgut junction mesentery synonym: "foregut-midgut junction mesentery" EXACT [VHOG:0000430] property_value: homology_notes "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {external_class="VHOG:0000430", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID\, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/", date_retrieved="2012-09-17"} def: "A mesentery that is part of a foregut-midgut junction." [OBOL:automatic] [Term] id: UBERON:0009484 name: dorsal mesentery of mesentery of foregut-midgut junction subset: emapa_ehdaa2 is_a: UBERON:0009483 ! mesentery of foregut-midgut junction xref: EHDAA2:0000571 ! foregut-midgut junction dorsal mesentery xref: EMAPA:16366 ! dorsal mesentery of mesentery of foregut-midgut junction [Term] id: UBERON:0010046 ! entire pharyngeal arch associated mesenchyme name: entire pharyngeal arch associated mesenchyme def: "The sum total of mesenchymal tissue in the pharyngeal arch region." [UBERON:cjm] is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: part_of UBERON:0008814 {source="EHDAA2"} ! pharyngeal system relationship: has_developmental_contribution_from UBERON:0003099 {source="cjm"} ! cranial neural crest synonym: "pharyngeal arch associated mesenchyme" EXACT [EHDAA2:0001459] synonym: "associated mesenchyme of pharyngeal region" EXACT [EMAPA:16550] synonym: "entire branchial arch associated mesenchyme" EXACT [UBERON:cjm] xref: EMAPA:16550 ! associated mesenchyme of pharyngeal region xref: EHDAA2:0001459 ! pharyngeal arch associated mesenchyme [Term] id: UBERON:0009494 name: pharyngeal arch mesenchymal region def: "A portion of mesenchymal tissue associated with an individual pharyngeal arch." [UBERON:cjm] comment: Editor notes: this represents a part of the entire arch mesenchyme (UBERON:0010046), and is therefore a superclass of the individual arch mesenchyme classes. Alternate definition: primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures. [MP:0011262] is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme relationship: has_developmental_contribution_from UBERON:0003099 {source="cjm"} ! cranial neural crest synonym: "branchial arch mesenchyme" EXACT [MP:0011262] synonym: "pharyngeal arch mesenchyme" EXACT [UBERON:cjm] [Term] id: UBERON:0009495 name: extrahepatic part of biliary bud subset: emapa_ehdaa2 is_a: UBERON:0007499 ! epithelial sac relationship: develops_from UBERON:0004912 {source="EHDAA2"} ! biliary bud xref: EHDAA2:0000172 ! biliary bud extrahepatic part xref: EMAPA:16562 ! extrahepatic part of biliary bud [Term] id: UBERON:0009496 name: intrahepatic part of biliary bud subset: emapa_ehdaa2 is_a: UBERON:0007499 ! epithelial sac relationship: develops_from UBERON:0004912 {source="EHDAA2"} ! biliary bud xref: EHDAA2:0000173 ! biliary bud intrahepatic part xref: EMAPA:16563 ! intrahepatic part of biliary bud [Term] id: UBERON:0009497 name: epithelium of foregut-midgut junction subset: emapa_ehdaa2 is_a: UBERON:0000490 ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006235 ! foregut-midgut junction xref: EHDAA2:0000573 ! foregut-midgut junction epithelium xref: EMAPA:16564 ! epithelium of foregut-midgut junction def: "An epithelium that is part of a foregut-midgut junction." [OBOL:automatic] [Term] id: UBERON:0009499 name: parietal of mesothelium of pericardio-peritoneal canal subset: emapa_ehdaa2 is_a: UBERON:0001136 ! mesothelium relationship: part_of UBERON:0007185 ! pericardio-peritoneal canal mesothelium xref: EHDAA2:0001409 ! parietal pericardio-peritoneal canal mesothelium xref: EMAPA:16590 ! parietal of mesothelium of pericardio-peritoneal canal [Term] id: UBERON:0009477 name: associated mesenchyme of otic placode subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003069 ! otic placode relationship: develops_from UBERON:0007213 ! mesenchyme derived from head neural crest xref: EHDAA2:0001340 ! otic placode associated mesenchyme xref: EMAPA:16196 ! associated mesenchyme of otic placode def: "Mesenchyme that is part of a otic placode." [OBOL:automatic] [Term] id: UBERON:0009500 name: associated mesenchyme of otocyst subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003051 ! ear vesicle relationship: develops_from UBERON:0009477 {source="EHDAA2"} ! associated mesenchyme of otic placode xref: EHDAA2:0001343 ! otocyst associated mesenchyme xref: EMAPA:16670 ! associated mesenchyme of otocyst def: "Mesenchyme that is part of a ear vesicle." [OBOL:automatic] [Term] id: UBERON:0009501 name: mesenchyme of fronto-nasal process def: "the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head" [MP:0011266] subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004066 ! frontonasal prominence relationship: develops_from UBERON:0007213 ! mesenchyme derived from head neural crest synonym: "frontonasal mesenchyme" EXACT [MP:0011266] synonym: "naso-frontal mesenchyme" EXACT [MP:0011266] xref: EHDAA2:0004109 ! frontonasal process mesenchyme xref: EMAPA:16683 ! mesenchyme of fronto-nasal process [Term] id: UBERON:0009502 name: ventral mesentery of mesentery of foregut-midgut junction subset: emapa_ehdaa2 is_a: UBERON:0009483 ! mesentery of foregut-midgut junction xref: RETIRED_EHDAA2:0000576 ! foregut-midgut junction ventral mesentery xref: EMAPA:16714 ! ventral mesentery of mesentery of foregut-midgut junction [Term] id: UBERON:0009503 name: associated mesenchyme of hindgut subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001046 ! hindgut xref: EHDAA2:0000780 ! hindgut associated mesenchyme xref: EMAPA:16716 ! associated mesenchyme of hindgut def: "Mesenchyme that is part of a hindgut." [OBOL:automatic] [Term] id: UBERON:0009504 name: associated mesenchyme of main bronchus subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002182 ! main bronchus xref: EHDAA2:0001045 ! main bronchus associated mesenchyme xref: EMAPA:16850 ! associated mesenchyme of main bronchus def: "Mesenchyme that is part of a main bronchus." [OBOL:automatic] [Term] id: UBERON:0009505 name: associated mesenchyme of trachea subset: emapa_ehdaa2 is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0002539 ! pharyngeal arch xref: EHDAA2:0002067 ! trachea associated mesenchyme xref: EMAPA:16854 ! associated mesenchyme of trachea def: "Mesenchyme that is part of a trachea." [OBOL:automatic] [Term] id: UBERON:0009506 name: associated mesenchyme of middle ear comment: Also 1st arch maxillary mesenchyme in EHDAA2 synonym: "middle ear associated mesenchyme" EXACT [EHDAA2:0001182] synonym: "otic mesenchyme" BROAD [] subset: emapa_ehdaa2 is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001756 ! middle ear relationship: has_developmental_contribution_from UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme relationship: has_developmental_contribution_from UBERON:0005689 {source="EHDAA2"} ! 2nd arch mesenchyme xref: EHDAA2:0001182 ! middle ear associated mesenchyme xref: EMAPA:17001 ! associated mesenchyme of middle ear def: "Mesenchyme that is part of a middle ear." [OBOL:automatic] [Term] id: UBERON:0009521 name: anal membrane endodermal component subset: emapa_ehdaa2 intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001353 ! anal region xref: EHDAA2:0004020 ! anal membrane endodermal component xref: EMAPA:17177 ! endoderm component of anal membrane def: "An endoderm that is part of a anal region." [OBOL:automatic] [Term] id: UBERON:0009522 name: lateral lingual swelling epithelium subset: emapa_ehdaa2 is_a: UBERON:0000490 ! unilaminar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006757 ! lateral lingual swelling xref: EHDAA2:0000913 ! lateral lingual swelling epithelium xref: EMAPA:17190 ! epithelium of lateral of lingual swelling def: "An epithelium that is part of a lateral lingual swelling." [OBOL:automatic] [Term] id: UBERON:0009536 name: vascular element of left lung subset: emapa_ehdaa2 intersection_of: UBERON:0005629 ! vascular plexus intersection_of: part_of UBERON:0002168 ! left lung xref: EHDAA2:0000963 ! left lung vascular element xref: EMAPA:17660 ! vascular element of left lung def: "A vascular plexus that is part of a left lung." [OBOL:automatic] [Term] id: UBERON:0009537 name: vascular element of right lung subset: emapa_ehdaa2 intersection_of: UBERON:0005629 ! vascular plexus intersection_of: part_of UBERON:0002167 ! right lung xref: EHDAA2:0001757 ! right lung vascular element xref: EMAPA:17668 ! vascular element of right lung def: "A vascular plexus that is part of a right lung." [OBOL:automatic] [Term] id: UBERON:0009538 name: mesenchyme of sublingual gland primordium subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006297 ! sublingual gland primordium relationship: develops_from UBERON:0003324 ! mesenchyme of lower jaw xref: EHDAA2:0001937 ! sublingual gland primordium mesenchyme xref: EMAPA:17754 ! mesenchyme of sublingual gland primordium def: "Mesenchyme that is part of a sublingual gland primordium." [OBOL:automatic] [Term] id: UBERON:0009539 name: mesenchyme of submandibular gland primordium subset: emapa_ehdaa2 intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006298 ! submandibular gland primordium relationship: develops_from UBERON:0003324 ! mesenchyme of lower jaw xref: EHDAA2:0001941 ! submandibular gland primordium mesenchyme xref: EMAPA:17757 ! mesenchyme of submandibular gland primordium def: "Mesenchyme that is part of a submandibular gland primordium." [OBOL:automatic] [Term] id: UBERON:0009548 name: hepatic sinusoid of left of lobe of liver subset: emapa_ehdaa2 intersection_of: UBERON:0001281 ! hepatic sinusoid intersection_of: part_of UBERON:0001115 ! left lobe of liver relationship: develops_in UBERON:0001115 ! left lobe of liver xref: EHDAA2:0001001 ! liver left lobe hepatic sinusoids xref: EMAPA:18309 ! hepatic sinusoid of left of lobe of liver xref: VHOG:0000709 ! left lobe hepatic sinusoids synonym: "left lobe hepatic sinusoids" EXACT [VHOG:0000709] def: "A hepatic sinusoid that is part of a left lobe of liver." [OBOL:automatic] [Term] id: UBERON:0009549 name: hepatic sinusoid of right of lobe of liver subset: emapa_ehdaa2 intersection_of: UBERON:0001281 ! hepatic sinusoid intersection_of: part_of UBERON:0001114 ! right lobe of liver relationship: develops_in UBERON:0001114 ! right lobe of liver xref: EHDAA2:0001009 ! liver right lobe hepatic sinusoids xref: EMAPA:18316 ! hepatic sinusoid of right of lobe of liver xref: VHOG:0000710 ! right lobe hepatic sinusoids synonym: "right lobe hepatic sinusoids" EXACT [VHOG:0000710] def: "A hepatic sinusoid that is part of a right lobe of liver." [OBOL:automatic] [Term] id: UBERON:0011737 name: caudate lobe hepatic sinusoids intersection_of: UBERON:0001281 ! hepatic sinusoid intersection_of: part_of UBERON:0001117 ! caudate lobe of liver relationship: develops_in UBERON:0001117 {source="EHDAA2"} ! caudate lobe of liver xref: VHOG:0000711 ! caudate lobe hepatic sinusoids xref: EMAPA:18314 ! hepatic sinusoid of caudate lobe (right) xref: EHDAA:6992 ! hepatic sinusoids xref: EHDAA2:0001006 ! liver right caudate lobe hepatic sinusoids synonym: "liver right caudate lobe hepatic sinusoids" EXACT [EHDAA2:0001006] def: "A hepatic sinusoid that is part of a caudate lobe of liver." [OBOL:automatic] [Term] id: UBERON:0011738 name: quadrate lobe hepatic sinusoids intersection_of: UBERON:0001281 ! hepatic sinusoid intersection_of: part_of UBERON:0001116 ! quadrate lobe of liver relationship: develops_in UBERON:0001116 {source="EHDAA2"} ! quadrate lobe of liver xref: VHOG:0000712 ! quadrate lobe hepatic sinusoids xref: EMAPA:18319 ! hepatic sinusoid of quadrate lobe (right) xref: EHDAA:8084 ! hepatic sinusoids xref: EHDAA2:0001013 ! liver right quadrate lobe hepatic sinusoids synonym: "liver right quadrate lobe hepatic sinusoids" EXACT [EHDAA2:0001013] def: "A hepatic sinusoid that is part of a quadrate lobe of liver." [OBOL:automatic] [Term] id: UBERON:0009550 name: endoderm of foregut-midgut junction subset: emapa_ehdaa2 intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0006235 ! foregut-midgut junction xref: EHDAA2:0000572 ! foregut-midgut junction endoderm xref: EMAPA:18403 ! endoderm of foregut-midgut junction def: "An endoderm that is part of a foregut-midgut junction." [OBOL:automatic] [Term] id: UBERON:0009644 name: trachea non-cartilage connective tissue is_a: UBERON:0003571 {source="MA"} ! trachea connective tissue xref: MA:0001859 ! trachea non-cartilage connective tissue [Term] id: UBERON:0009645 name: ampullary gland def: "fusiform enlargement of the deferent duct, as it passes across the bladder wall, due to proliferation of glandular tissue in the regionally folded mucosa." [http://medical-dictionary.thefreedictionary.com/ampullary+gland] comment: Ampullary glands are situated in an ampulla-like enlargement of the seminal duct, or embedded in the latter; they are present, eg in the Shrew, Ruminants, and certain Carnivores and Rodents. (Wiedersheim et al., 1907)[MorphoBank] synonym: "ampullary gland of seminal duct" EXACT [] is_a: UBERON:0005399 {source="MA"} ! male reproductive gland relationship: part_of UBERON:0006946 ! efferent duct xref: MA:0000400 ! ampullary gland xref: ncithesaurus:Ampullary_Gland ! Ampullary Gland xref: UMLS:C2698103 [Term] id: UBERON:0009646 name: lumbar sympathetic nerve trunk intersection_of: UBERON:0004295 ! sympathetic nerve trunk intersection_of: part_of UBERON:0005462 ! lower back xref: MA:0001163 ! lumbar sympathetic nerve trunk xref: ncithesaurus:Lumbar_Sympathetic_Nerve_Trunk ! Lumbar Sympathetic Nerve Trunk def: "A sympathetic nerve trunk that is part of a lower back." [OBOL:automatic] xref: UMLS:C1708762 [Term] id: UBERON:0009650 name: cortical arch of kidney def: "The portions of renal substance (cortex) intervening between the bases of the pyramids and the capsule of the kidney." [http://www.medilexicon.com/medicaldictionary.php?t=5968] synonym: "cortical arches of kidney" RELATED PLURAL [] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002189 {source="MA"} ! outer cortex of kidney xref: MA:0001650 ! cortical arch xref: ncithesaurus:Cortical_Arch ! Cortical Arch xref: UMLS:C1511525 [Term] id: UBERON:0009651 name: nephron tubule basement membrane intersection_of: UBERON:0005769 ! basement membrane intersection_of: part_of UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0001231 {source="MA"} ! nephron tubule synonym: "renal tubule basement membrane" EXACT [MA:0001680] xref: MA:0001680 ! renal tubule basement membrane xref: ncithesaurus:Renal_Tubule_Basement_Membrane ! Renal Tubule Basement Membrane synonym: "kidney tubule basement membrane" EXACT [MA:0001680] def: "A basement membrane that is part of a nephron tubule." [OBOL:automatic] relationship: part_of UBERON:0004810 {is_inferred="true", source="reference_0000032"} ! nephron tubule epithelium xref: UMLS:C1709901 [Term] id: UBERON:0009652 name: bronchus basement membrane intersection_of: UBERON:0005769 ! basement membrane intersection_of: part_of UBERON:0002185 ! bronchus is_a: UBERON:0003592 {source="MA"} ! bronchus connective tissue xref: MA:0001832 ! bronchus basement membrane xref: ncithesaurus:Bronchus_Basement_Membrane ! Bronchus Basement Membrane def: "A basement membrane that is part of a bronchus." [OBOL:automatic] relationship: part_of UBERON:0002031 {is_inferred="true", source="reference_0000032"} ! epithelium of bronchus xref: UMLS:C1707051 [Term] id: UBERON:0009653 name: trachea basement membrane intersection_of: UBERON:0005769 ! basement membrane intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0009644 {source="MA-modified"} ! trachea non-cartilage connective tissue xref: MA:0001854 ! trachea basement membrane xref: ncithesaurus:Trachea_Basement_Membrane ! Trachea Basement Membrane def: "A basement membrane that is part of a trachea." [OBOL:automatic] relationship: part_of UBERON:0001901 {is_inferred="true", source="reference_0000032"} ! epithelium of trachea xref: UMLS:C1710455 [Term] id: UBERON:0009654 name: alveolar artery comment: add child terms is_a: UBERON:0001637 {source="MA"} ! artery xref: MA:0001913 ! alveolar artery xref: ncithesaurus:Alveolar_Artery ! Alveolar Artery xref: UMLS:C1706783 [Term] id: UBERON:0009655 name: auricular artery comment: add child terms is_a: UBERON:0001637 {source="MA"} ! artery xref: MA:0001918 ! auricular artery xref: ncithesaurus:Auricular_Artery ! Auricular Artery xref: UMLS:C1706858 [Term] id: UBERON:0009656 name: obsolete frontal artery consider: MA:0001960 ! frontal artery is_obsolete: true comment: insufficiently defined [Term] id: UBERON:0009660 name: adrenal vein is_a: UBERON:0001638 {source="MA"} ! vein xref: MA:0002081 ! adrenal vein xref: ncithesaurus:Adrenal_Vein ! Adrenal Vein [Term] id: UBERON:0009661 name: midbrain nucleus def: "Nucleus located in the midbrain." [ZFIN:curator] xref: TAO:0002209 ! midbrain nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001891 ! midbrain xref: ZFA:0001665 ! midbrain nucleus xref: SCTID:279285003 ! Midbrain nucleus [Term] id: UBERON:0009662 name: hindbrain nucleus def: "Nucleus located within the hindbrain." [ZFIN:curator] xref: TAO:0002177 ! hindbrain nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002028 ! hindbrain xref: ZFA:0001658 ! hindbrain nucleus [Term] id: UBERON:0009663 name: telencephalic nucleus xref: TAO:0002178 ! telencephalic nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001893 ! telencephalon xref: ZFA:0001660 ! telencephalic nucleus def: "A nucleus of brain that is part of a telencephalon." [OBOL:automatic] [Term] id: UBERON:0009671 name: nasal fin def: "The nasal fin is an epithelial seam that develops by fusion between the epithelial linings of the medial and lateral nasal swellings. Shortly after its formation the nasal fin regresses and is replaced by mesenchyme, with exception of its most posterior portion which remains as the bucconasal membrane." [DOI:10.1002/aja.1001500308] is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0005384 {source="EHDAA2"} ! nasal cavity epithelium relationship: part_of UBERON:0002424 {source="EHDAA2"} ! oral epithelium xref: EHDAA2:0004548 ! nasal fin [Term] id: UBERON:0009672 name: oronasal membrane def: "The oronasal membrane separates the oral cavity and nasal cavity. In humans, the oronasal membrane ruptures during the seventh week, producing a single, large oronasal cavity" [http://cwx.prenhall.com/bookbind/pubbooks/martini10/chapter24/custom3/deluxe-content.html] synonym: "bucconasal membrane" EXACT [EHDAA:7840] comment: split into two? is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: part_of UBERON:0005384 {source="EHDAA2"} ! nasal cavity epithelium relationship: part_of UBERON:0000166 {source="EHDAA2"} ! oral opening relationship: develops_from UBERON:0009671 {source="EHDAA2"} ! nasal fin xref: EHDAA2:0000188 ! oronasal membrane xref: EHDAA:7840 ! bucconasal membrane xref: EHDAA:7984 ! bucconasal membrane [Term] id: UBERON:0009687 name: middle cardiac vein def: "The middle cardiac vein commences at the apex of the heart, ascends in the posterior longitudinal sulcus, and ends in the coronary sinus near its right extremity." [Wikipedia:Middle_cardiac_vein] synonym: "vena cardiaca media" RELATED LATIN [Wikipedia:Middle_cardiac_vein] synonym: "lesser cardiac vein" EXACT [FMA:4713] synonym: "posterior interventricular vein" EXACT [FMA:4713] is_a: UBERON:0004148 {source="FMA"} ! cardiac vein xref: FMA:4713 ! middle cardiac vein xref: EHDAA2:0004509 ! middle cardiac vein xref: ncithesaurus:Middle_Cardiac_Vein ! Middle Cardiac Vein xref: SCTID:277729002 ! Entire middle cardiac vein xref: UMLS:C0226660 [Term] id: UBERON:0009695 name: epithelium of laryngopharynx synonym: "epithelium of laryngeal pharynx" EXACT [FMA:62454] synonym: "laryngopharynx epithelium" EXACT [FMA:62454] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001051 ! hypopharynx relationship: develops_from UBERON:0007690 {source="EHDAA2"} ! early pharyngeal endoderm relationship: part_of UBERON:0003929 {source="EHDAA2"} ! gut epithelium relationship: part_of UBERON:0001051 {source="EHDAA2"} ! hypopharynx xref: EHDAA2:0004575 ! laryngopharynx epithelium xref: FMA:62454 ! epithelium of laryngopharynx [Term] id: UBERON:0009697 name: epithelium of appendix synonym: "appendix epithelium" EXACT [FMA:63581] synonym: "epithelium of vermiform appendix" EXACT [FMA:63581] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001154 ! appendix relationship: part_of UBERON:0004989 ! mucosa of appendix relationship: part_of UBERON:0003929 {source="EHDAA2"} ! gut epithelium relationship: develops_from UBERON:0005636 {source="EHDAA2"} ! caecum epithelium xref: EHDAA2:0004561 ! appendix epithelium xref: FMA:63581 ! epithelium of appendix [Term] id: UBERON:0009474 ! ascidian ampulla name: ascidian ampulla synonym: "ampulla" BROAD [] is_a: UBERON:0000026 ! appendage relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009475 name: ampullar siphon is_a: UBERON:0000026 ! appendage relationship: part_of UBERON:0009474 ! ascidian ampulla [Term] id: UBERON:0011302 name: tunicate tunic def: "Outer covering of an animal typically consisting primarily of cellulose (tunicin) in addition to varying amounts of water, protein and carbohydrates. The tunicate is a characteristic feature of Tunicata" [ISBN:0030229073, Wikipedia:Ascidiacea#Anatomy] comment: Taxon notes: In some species tunicin occurs in small amounts. Some species calcium salts are deposited as spicules. In ascidians, the tunic is supplied with blood vessels. is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0002416 ! integumental system relationship: surrounds UBERON:0000468 ! multi-cellular organism relationship: only_in_taxon NCBITaxon:7712 ! Tunicata relationship: part_of UBERON:0007023 ! adult organism relationship: composed_primarily_of CHEBI:18246 ! (1->4)-beta-D-glucan [Term] id: UBERON:0011304 name: tunicate postabdomen def: "Basalmost subdivision of a tunicate containing the heart and reproductive organs" [ISBN:0030229073] comment: Taxon notes: Most ascidians lack a postabdomen is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009716 name: cupular organ def: "Epithelial sense organ containing the cupula housing a gelatinous material elongated from the basement of the organ toward the atrial cavity. The basement of the cupular organ consists of two cell types: sensory cells and support cell" [DOI:10.2108/zsj.27.842] comment: Homology: possible homologues of neuromasts in the inner ear (Bone & Ryan, 1978; Wada et al 1998). In the tunicate cupular organ, the sensory cell is a primary neuron sending an axon to the CNS. The sensory cilium is within a deep indentation of the cell and is surrounded by a collar of short microvilli. is_a: UBERON:0000020 ! sense organ relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009717 name: coronal organ def: "Mechanoreceptor organ found in oral siphon of botryllid ascidians, made of hair cells, similar to the vertebrate octavolateralis system. A possible candidate of the vertebrate lateral line." [DOI:10.1002/jez.b.21013] is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0009720 ! oral siphon relationship: only_in_taxon NCBITaxon:7712 ! Tunicata subset: organ_slim [Term] id: UBERON:0009894 ! siphon primordium name: siphon primordium xref: ANISEED:1210451 ! siphon primordia is_a: UBERON:0005423 ! developing anatomical structure [Term] id: UBERON:0009719 name: siphon def: "tubular appendage for drawing or ejecting fluids" [] xref: BTO:0002056 ! siphon is_a: UBERON:0000026 ! appendage relationship: develops_from UBERON:0009894 ! siphon primordium [Term] id: UBERON:0009896 ! oral siphon primordia name: oral siphon primordia xref: ANISEED:1225922 ! oral siphon primordium (pharynx) is_a: UBERON:0009894 ! siphon primordium relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009720 ! oral siphon name: oral siphon synonym: "pharyngeal siphon" RELATED [] synonym: "branchial siphon" RELATED [] synonym: "buccal siphon" EXACT [ISBN:0030229073] synonym: "anterior buccal siphon" EXACT [ISBN:0030229073] is_a: UBERON:0009719 ! siphon relationship: develops_from UBERON:0009896 ! oral siphon primordia relationship: only_in_taxon NCBITaxon:7712 ! Tunicata property_value: foaf-depicted_by http://content61.eol.org/content/2010/04/23/02/32371_orig.jpg {source="http://eol.org/data_objects/6673409"} [Term] id: UBERON:0009895 ! atrial siphon primordia name: atrial siphon primordia xref: ANISEED:1210456 ! atrial siphon primordia is_a: UBERON:0009894 ! siphon primordium relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009721 name: atrial siphon is_a: UBERON:0009719 ! siphon relationship: develops_from UBERON:0009895 ! atrial siphon primordia relationship: only_in_taxon NCBITaxon:7712 ! Tunicata [Term] id: UBERON:0009892 ! ascidian anterior sensory vesicle name: ascidian anterior sensory vesicle is_a: UBERON:0000020 ! sense organ relationship: only_in_taxon NCBITaxon:7712 ! Tunicata xref: ANISEED:777309 ! anterior sensory vesicle [Term] id: UBERON:0009893 name: ascidian ocellus is_a: UBERON:0000020 ! sense organ relationship: part_of UBERON:0009892 ! ascidian anterior sensory vesicle xref: ANISEED:874489 ! ocellus [Term] id: UBERON:0009742 name: proamniotic cavity def: "the cavity of the developing embryo that is formed within the epiblast tissue prior to the closing of the proamniotic canal by the amniotic folds" [MP:0011197] is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0009743 name: visceral yolk sac cavity def: "the closed space containing the yolk, formed by the fusion of the edges of the embryonic epiblast (hypoblast) and later surrounded by the visceral yolk sac (hypoblast and visceral yolk sac mesoderm)" [MP:0011201] is_a: UBERON:0002050 ! embryonic structure intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0008852 ! visceral yolk sac relationship: part_of UBERON:0008852 ! visceral yolk sac [Term] id: UBERON:0009744 ! lymph node medullary sinus name: lymph node medullary sinus def: "the channels in the lymph node medulla that separate the medullary cords and are crossed by a reticulum of cells and fibers and bounded by littoral cells; lymph flows through the medullary sinus from the cortical sinuses and into the efferent lymphatic vessels" [MP:0011222] is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0002007 ! medulla of lymph node [Term] id: UBERON:0009745 name: lymph node medullary cord def: "the dense rope-like structures of lymphatic tissue located between the medullary sinuses in the medulla of a lymph node" [MP:0011224] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0002007 ! medulla of lymph node relationship: adjacent_to UBERON:0009744 ! lymph node medullary sinus [Term] id: UBERON:0009746 name: head fold of embryonic disc def: "the crescent-shaped, ventrally located fold of the embryonic disc at the future cephalic end of the developing embryo" [MP:0011257] is_a: UBERON:0005291 ! embryonic tissue disjoint_from: UBERON:0005062 ! neural fold xref: SCTID:361453004 ! Head fold synonym: "head fold" EXACT [] [Term] id: UBERON:0009747 name: tail fold of embryonic disc def: "the crescent-shaped, ventrally located fold of the embryonic disc at the future caudal end of the developing embryo" [MP:0011258] is_a: UBERON:0005291 ! embryonic tissue xref: SCTID:361439004 ! Tail fold synonym: "tail fold" EXACT [] [Term] id: UBERON:0009748 name: cephalic neural fold def: "the elevated margins of the neural groove that are located in the future cephalic region of the embryo" [MP:0011259] is_a: UBERON:0005062 ! neural fold xref: EMAPA:16090 ! neural fold [Term] id: UBERON:0009749 ! limb mesenchyme name: limb mesenchyme def: "the primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells." [MP:0011261] comment: AO notes: EMAPA mapping from TH synonym: "limb mesoderm" RELATED [Geisha:syn, NCBITaxon:8782] intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002101 ! limb xref: EMAPA:32705 ! limb mesenchyme [Term] id: UBERON:0009753 name: adrenal gland cortex zone is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001235 {source="MA"} ! adrenal cortex xref: MA:0001887 ! adrenal gland cortex zone xref: FMA:69086 ! region of adrenal cortex xref: SCTID:68594002 ! Adrenal cortex structure synonym: "region of adrenal cortex" RELATED [FMA:69086] synonym: "adrenal cortical region" EXACT [FMA:69086] [Term] id: UBERON:0009754 name: blubber def: "a thick layer of vascularized adipose tissue found under the skin of all cetaceans, pinnipeds and sirenians." [Wikipedia:Blubber] comment: Lipid-rich, collagen fiber–laced blubber comprises the hypodermis and covers the whole body, except for parts of the appendages, strongly attached to the musculature and skeleton by highly organized, fan-shaped networks of tendons and ligaments. It can comprise up to 50% of the body mass of some marine mammals during some points in their lives, and can range from two inches (5 cm) thick in dolphins and smaller whales, to more than 12 inches (30 cm)thick in some bigger whales, such as right and bowhead whales is_a: UBERON:0002190 {source="Wikipedia"} ! subcutaneous adipose tissue relationship: only_in_taxon NCBITaxon:40674 ! Mammalia xref: SCTID:83953006 ! Blubber [Term] id: UBERON:0009755 ! spermaceti name: spermaceti def: "wax present in the head cavities of the sperm whale." [Wikipedia:Spermaceti] is_a: UBERON:0000463 ! portion of organism substance relationship: part_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:9753 ! Physeter [Term] id: UBERON:0009756 ! spermaceti organ name: spermaceti organ def: "An organ that secretes a spermaceti." [OBOL:automatic] intersection_of: UBERON:0000062 ! organ intersection_of: secretes UBERON:0009755 ! spermaceti relationship: part_of UBERON:0000033 ! head subset: organ_slim xref: http://upload.wikimedia.org/wikipedia/commons/thumb/3/3b/Sperm_whale_head_anatomy.svg/1000px-Sperm_whale_head_anatomy.svg.png [Term] id: UBERON:0009757 name: ambergris def: "a biliary secretion of the intestines of the sperm whale." [Wikipedia:Ambergris] is_a: UBERON:0000463 ! portion of organism substance relationship: only_in_taxon NCBITaxon:9753 ! Physeter [Term] id: UBERON:0009842 name: acinus def: "An acinus refers to any cluster of cells that resembles a many-lobed \"berry,\" such as a raspberry (acinus is Latin for berry). The berry-shaped termination of an exocrine gland, where the secretion is produced is acinar in form, as is the alveolar sac containing multiple alveoli in the lungs." [Wikipedia:Acinus] synonym: "glandular acinus" RELATED [] synonym: "acini" RELATED PLURAL [Wikipedia:Acinus] property_value: has_relational_adjective "acinar" xsd:string is_a: UBERON:0000064 ! organ part xref: FMA:55588 ! acinus xref: http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png [Term] id: UBERON:0013223 name: alveolar gland def: "In contrast to tubular glands, in the second main variety of gland, the secretory portion is enlarged and the lumen variously increased in size. These are termed alveolar glands (or saccular glands, or acinar glands, or acinous glands). Some sources draw a clear distinction between acinar and alveolar glands, based upon the shape of the lumen. A further complication in the case of the alveolar glands may occur in the form of still smaller saccular diverticuli growing out from the main sacculi. These are termed alveoli. The term \"tubulo-alveolar\" (or \"tubulo-acinar\", or \"compound tubulo-acinar\", or \"compound tubulo-alveolar\") is used to describe glands that start out as branched tubular, and branch further to terminate in alveoli. This type of gland is found in the salivary glands, esophagus, and mammary glands. The term \"racemose gland\" is used to describe a \"compound alveolar gland\" or \"compound acinar gland\"." [Wikipedia:Alveolar_gland] xref: http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png synonym: "alveolar gland" RELATED [Wikipedia:Alveolar_gland] synonym: "saccular gland" RELATED [Wikipedia:Alveolar_gland] synonym: "acinar gland" RELATED [Wikipedia:Alveolar_gland] is_a: UBERON:0002530 {source="Wikipedia"} ! gland xref: Wikipedia:Alveolar_gland ! alveolar gland [Term] id: UBERON:0009917 name: kidney corticomedullary boundary def: "the region demarcating the renal medulla from the surrounding cortex; end-stage renal failure may be associated with loss of the normal corticomedullary boundary" [MP:0011376] intersection_of: UBERON:0000015 ! anatomical boundary intersection_of: adjacent_to UBERON:0000362 ! renal medulla intersection_of: adjacent_to UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0002113 {source="MP"} ! kidney [Term] id: UBERON:0009918 name: retrotrapezoid nucleus def: "the loose collection of neurons that reside in the rostral medulla close to the medullary surface, ventral and immediately caudal of nVII, that are crucial for CO2 sensing in the brain" [MP:0011406] is_a: UBERON:0000125 {source="cjm"} ! neural nucleus relationship: part_of UBERON:0001896 {source="MP"} ! medulla oblongata [Term] id: UBERON:0009919 name: ureter smooth muscle def: "the smooth muscle tissue surrounding the epithelium of the ureter" [MP:0011426] xref: EMAPA:28844 ! ureteral smooth muscle layer of ureter synonym: "ureteral smooth muscle layer" EXACT [EMAPA:28844] synonym: "ureteral smooth muscle" EXACT [MP:0011426] intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0006855 ! ureter muscle layer [Term] id: UBERON:0009921 name: hypophyseal tube is_a: UBERON:0000025 ! tube relationship: only_in_taxon NCBITaxon:7746 ! Petromyzontidae [Term] id: UBERON:0009972 name: ureteropelvic junction def: "the junction between the ureter and the renal pelvis of the kidney" [MP:0011487] synonym: "pelviureteric junction" EXACT [FMA:15898] synonym: "pelvoureteric junction" EXACT [] relationship: part_of UBERON:0001008 {source="MP"} ! excretory system intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000056 ! ureter intersection_of: connects UBERON:0001224 ! renal pelvis xref: MA:0003021 ! ureteropelvic junction xref: FMA:15898 ! ureteropelvic junction xref: SCTID:264130006 ! Entire ureteropelvic junction [Term] id: UBERON:0009973 name: ureterovesical junction def: "the valve-like structure found at the site of entry of the ureter into the urinary bladder, normally displays an oblique angulation through the detrusor to avoid reflux of urine up the ureters and the kidney" [MP:0011488] synonym: "vesico-ureteral junction" EXACT [MA:0003020] synonym: "vesico-ureteric junction" EXACT [] synonym: "vesicoureteric junction" EXACT [] is_a: UBERON:0003978 ! valve relationship: part_of UBERON:0001008 {source="MP"} ! excretory system intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000056 ! ureter intersection_of: connects UBERON:0001255 ! urinary bladder xref: FMA:15899 ! ureterovesical junction xref: MA:0003020 ! ureterovesical junction xref: SCTID:261187001 ! Vesicoureteric junction [Term] id: UBERON:0010002 name: pulmonary neuroendocrine body def: "corpuscular, organoid structures composed of PNECs, found as distinctive innervated clusters only within intrapulmonary airways, where they appear concentrated at airway branch points; NEBs reach from the basement membrane to the airway lumen and are thought to function as oxygen sensors." [MP:0010921] synonym: "pulmonary neuroepithelial body" EXACT [MP:0010921] synonym: "NEB" EXACT [MP:0010921] is_a: UBERON:0000061 {source="MP"} ! anatomical structure relationship: has_part CL:0000165 ! neuroendocrine cell relationship: part_of UBERON:0000115 ! lung epithelium [Term] id: UBERON:0010005 name: placental labyrinth villi def: "the vascularized and branched structures arising from the rodent trophoblast-derived epithelium that allow an increase its surface area for the efficient exchange of nutrients and wastes between the maternal and fetal circulation" [MP:0011522] is_a: UBERON:0000061 {source="MP"} ! anatomical structure relationship: part_of UBERON:0003946 {source="MP"} ! placenta labyrinth [Term] id: UBERON:0010006 name: placenta intervillous maternal lacunae def: "the spaces of the placenta occupied by maternal blood, into which the fetal labyrinth villi project" [MP:0011525] is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0003946 {source="MP"} ! placenta labyrinth [Term] id: UBERON:0010007 name: placenta fetal blood space def: "the spaces of the placenta occupied by fetal blood, primarily within the fetal labyrinth villi" [MP:0011526] is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0003946 {source="MP"} ! placenta labyrinth [Term] id: UBERON:0010172 name: bulb of aorta def: "the portion of the left ventricular outflow tract delineated by the sinotubular ridge superiorly and the bases of the valve leaflets inferiorly; it comprises the aortic sinuses, the aortic valve leaflets, the commissures, and the interleaflet triangles" [MP:0011572] synonym: "aortic bulb" EXACT [FMA:3740] synonym: "bulb of ascending aorta" EXACT [FMA:3740] synonym: "bulbus aortae" EXACT LATIN [FMA:TA] synonym: "root of aorta" EXACT [FMA:3740] synonym: "supraaortic valve area" EXACT [FMA:3740] synonym: "aortic root" EXACT [MP:0011572] synonym: "aorta bulb" EXACT [MP:0011575] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001496 {source="FMA"} ! ascending aorta xref: FMA:3740 ! bulb of aorta xref: SCTID:362032000 ! Entire supraaortic valve area property_value: external_definition "The dilated first part of the aorta containing the aortic semilunar valves and the aortic sinuses." xsd:string {source="http://medical-dictionary.thefreedictionary.com/aortic+bulb"} [Term] id: UBERON:0010173 name: sinotubular junction def: "the point in the ascending aorta where the aortic sinuses end and the aorta becomes a tubular structure" [MP:0011572] synonym: "sinotubular ridge" EXACT [MP:0011572] is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0001496 {source="MP"} ! ascending aorta [Term] id: UBERON:0010181 name: straight venules of kidney def: "The straight venules of kidney are branches from the plexuses at the apices of the medullary pyramids, formed by the terminations of the arteriae rectae. They run outward in a straight course between the tubes of the medullary substance, and joining, as above stated, the interlobular veins, form venous arcades; these in turn unite and form veins which pass along the sides of the pyramids. Contains fenestrated capillaries." [Wikipedia:Straight_venules_of_kidney] synonym: "venae rectae" RELATED [Wikipedia:Straight_venules_of_kidney] synonym: "venulae rectae" RELATED [Wikipedia:Straight_venules_of_kidney] synonym: "venulae recti" RELATED [Wikipedia:Straight_venules_of_kidney] synonym: "venulae rectae of kidney" EXACT [FMA:72007] synonym: "venulae rectae renis" EXACT LATIN [FMA:TA] synonym: "set of straight venules of kidney" EXACT [FMA:72007] xref: Wikipedia:Straight_venules_of_kidney ! straight venules of kidney xref: FMA:72007 ! set of straight venules of kidney is_a: UBERON:0005629 ! vascular plexus relationship: part_of UBERON:0002113 ! kidney synonym: "venulae rectae renis" RELATED LATIN [Wikipedia:Straight_venules_of_kidney] xref: SCTID:245983001 ! Entire venulae rectae [Term] id: UBERON:0010188 name: protuberance def: "A roughly circular bulge in a surface." [EHDAA2:0003250] xref: AEO:0000205 is_a: UBERON:0003102 {source="EHDAA2"} ! surface structure xref: EHDAA2:0003250 ! protuberance xref: FMA:82506 ! protuberance [Term] id: UBERON:1000000 name: chin ventral margin def: "Subdivision of the head consisting of the area along the lower edge of the chin." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0008199 ! chin [Term] id: UBERON:1000001 name: collection of hairs on vertex def: "A collection of hairs that grows on the vertex (top of head)." [UBERON:EJS] synonym: "collection of hair on cranium" RELATED [] synonym: "cranial hair" RELATED [] subset: phenotype_rcn is_a: UBERON:0010164 ! collection of hairs relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:1000002 name: cranial midline area def: "The middle part of the head, located approximately equidistant from the left and the right sides of the head." [UBERON:EJS] synonym: "cranial midline" RELATED [] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head [Term] id: UBERON:1000004 name: collection of hair on ear def: "A collection of hairs that grows on the external ear." [UBERON:EJS] synonym: "external ear hair" RELATED [] subset: phenotype_rcn is_a: UBERON:0010164 ! collection of hairs [Term] id: UBERON:1000005 name: external ear margin def: "Subdivision of the head consisting of the area along the edge of the external ear." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001691 ! external ear [Term] id: UBERON:1000006 name: collection of hair on forehead def: "A collection of hairs that grows on the forehead." [UBERON:EJS] subset: phenotype_rcn intersection_of: UBERON:0010164 ! collection of hairs intersection_of: part_of UBERON:0008200 ! forehead [Term] id: UBERON:1000007 name: forehead protuberance def: "A bulge, knob, or swelling that protrudes from the forehead." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0008200 ! forehead [Term] id: UBERON:1000008 name: left part of face def: "Subdivision of the head consisting of the left half of the face, vertically divided." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: in_left_side_of UBERON:0001456 ! face relationship: part_of UBERON:0001456 ! face [Term] id: UBERON:1000009 name: midline crest def: "A ridge or peak located along the middle part of the head, located approximately equidistant from the left and the right sides of the head." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head [Term] id: UBERON:1000010 name: mole def: "A benign tumor on the skin, usually with darker pigment." [Wikipedia:Melanocytic_nevus] synonym: "melanocytic nevus" RELATED [] synonym: "naevus" EXACT [ZFA:0005043] synonym: "nevus" EXACT [ZFA:0005043] subset: phenotype_rcn is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0002067 {source="ZFA"} ! dermis relationship: has_part CL:0000148 ! melanocyte xref: ZFA:0005043 ! nevus xref: TAO:0005043 ! nevi property_value: external_definition "An ectopic melanophore accumulation analogous to a nevi (mole) in humans.[TAO]" xsd:string {ontology="TAO", external_class="TAO:0005043", date_retrieved="2012-08-14", source="ZFIN:curator"} xref: EFO:0000625 ! nevus [Term] id: UBERON:1000011 name: labial commissure def: "Anatomical structure consisting of either corner of the mouth." [Wikipedia:Labial_commissure_of_mouth] synonym: "corner of mouth" RELATED [] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0000165 ! mouth synonym: "commissura labiorum oris" RELATED LATIN [Wikipedia:Labial_commissure_of_mouth] xref: http://upload.wikimedia.org/wikipedia/commons/9/90/Commissurebeforeandafter.jpg [Term] id: UBERON:1000012 name: nose anterior margin def: "Subdivision of the head consisting of the area along the front edge of the external nose." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0007827 ! external nose [Term] id: UBERON:1000013 name: nose vertex def: "The extreme point of curvature of the external nose." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0007827 ! external nose [Term] id: UBERON:1000014 name: right part of face def: "Subdivision of the head consisting of the right half of the face, vertically divided." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001456 ! face relationship: in_right_side_of UBERON:0001456 ! face [Term] id: UBERON:1000015 name: skin of snout def: "A zone of skin that is part of the snout." [UBERON:EJS] subset: phenotype_rcn intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0006333 ! snout [Term] id: UBERON:1000016 name: tip of snout def: "Subdivision of the head consisting of the pointed or rounded end or extremity of the snout." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0006333 ! snout [Term] id: UBERON:1000017 name: tip of external ear def: "Subdivision of the head consisting of the pointed or rounded end or extremity of the external ear." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001691 ! external ear [Term] id: UBERON:1000018 name: cluster of hairs def: "A small collection or tuft of hairs." [UBERON:EJS] synonym: "tuft of hair" RELATED [] subset: phenotype_rcn is_a: UBERON:0010164 ! collection of hairs [Term] id: UBERON:1000019 name: top of head def: "The top of the head." [UBERON:EJS] comment: note in the FMA, vertex is a point and not a subdivision subset: phenotype_rcn is_a: UBERON:0001444 ! subdivision of head xref: FMA:46484 ! vertex xref: SCTID:362616002 ! Entire vertex synonym: "vertex" RELATED [FMA:46484] synonym: "vertex of head" EXACT [FMA:46484] [Term] id: UBERON:1000020 name: collection of hair on snout def: "A collection of hairs that grows on the snout." [UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0010165 ! collection of hair on face relationship: part_of UBERON:0006333 ! snout created_by: eriks creation_date: 2012-02-05T05:21:29Z [Term] id: UBERON:1000021 name: skin of face def: "A zone of skin that is part of the face." [UBERON:EJS] synonym: "facial skin" RELATED [] subset: phenotype_rcn intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001456 ! face created_by: eriks creation_date: 2012-02-05T05:23:01Z xref: ncithesaurus:Skin_of_the_Face ! skin of the face xref: FMA:24758 ! Skin of face xref: SCTID:361703006 ! Entire skin of face synonym: "face skin" EXACT [FMA:24758] xref: UMLS:C0222084 [Term] id: UBERON:0013633 name: intertrochanteric crest def: "The intertrochanteric crest is a bony ridge located on the posterior side of the head of the femur, stretching obliquely downward and medially from the summit of the greater trochanter to the lesser trochanter. Together with the intertrochanteric line on the anterior side of the head, the crest mark the transition between of the neck of femur into the shaft of femur. An elevation between the middle and proximal third of the crest is known as the quadrate tubercle. The upper half of the crest forms the posterior border of the greater trochanter. The distal capsular attachment on the femur follows the shape of the irregular rim between the head and the neck. As a consequence, the capsule of the hip joint attaches in the region of the intertrochanteric line on the anterior side, but a finger away from the intertrochanteric crest on the posterior side of the head." [Wikipedia:Intertrochanteric_crest] is_a: UBERON:0006800 ! anatomical line relationship: part_of UBERON:0004412 ! proximal epiphysis of femur relationship: connects UBERON:0002503 ! greater trochanter relationship: connects UBERON:0002504 ! lesser trochanter xref: FMA:75100 ! intertrochanteric crest [Term] id: UBERON:0013634 name: intertrochanteric line def: "The intertrochanteric line (or spiral line of the femur) is a line located on the anterior side of the proximal end of the femur. The rough, variable ridge stretches between the lesser trochanter and the greater trochanter forming the base of the neck of the femur, roughly following the direction of the shaft of the femur. The iliofemoral ligament — the largest ligament of the human body — attaches above the line which also strengthen the capsule of the hip joint. The lower half, less prominent than the upper half, gives origin to the upper part of the Vastus medialis. Just like the intertrochanteric crest on the posterior side of the femural head, the intertrochanteric line mark the transition between the femural neck and shaft. The distal capsular attachment on the femur follows the shape of the irregular rim between the head and the neck. As a consequence, the capsule of the hip joint attaches in the region of the intertrochanteric line on the anterior side, but a finger away from the intertrochanteric crest on the posterior side of the head. The fibers of the ischiocapsular ligament attaches both on the joint capsule and to the intertrochanteric line." [Wikipedia:Intertrochanteric_line] is_a: UBERON:0006800 {source="FMA"} ! anatomical line relationship: part_of UBERON:0004412 ! proximal epiphysis of femur xref: FMA:74587 ! intertrochanteric line [Term] id: UBERON:0010222 name: anatomical line between pupils synonym: "interpupillary line" EXACT [] is_a: UBERON:0006800 ! anatomical line relationship: connects UBERON:0010224 ! right pupil relationship: connects UBERON:0010223 ! left pupil relationship: part_of UBERON:0001456 ! face [Term] id: UBERON:0010231 name: anatomical line between outer ears synonym: "otic line" RELATED [] is_a: UBERON:0006800 ! anatomical line relationship: connects UBERON:0006617 ! left external ear relationship: connects UBERON:0006616 ! right external ear [Term] id: UBERON:0010210 name: blood clot def: "A semisolid gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets entrapped in a fibrin network." [BTO:0000102, Wikipedia:Thrombus] synonym: "thrombus" RELATED [BTO:0000102] is_a: UBERON:0000463 ! portion of organism substance relationship: develops_from UBERON:0000178 {source="BTO"} ! blood relationship: output_of GO:0007596 ! blood coagulation xref: BTO:0000102 ! blood clot xref: galen:BloodClot ! blood clot [Term] id: UBERON:0010211 name: granulation tissue def: "Highly vascularized tissue that replaces the initial fibrin clot in a wound. Vascularization is by ingrowth of capillary endothelium from the surrounding vasculature. The tissue is also rich in fibroblasts (that will eventually produce the fibrous tissue) and leucocytes." [BTO:0003257] is_a: UBERON:0002384 {source="BTO"} ! connective tissue relationship: participates_in GO:0042060 ! wound healing relationship: has_part CL:0000057 ! fibroblast relationship: has_part CL:0000738 ! leukocyte xref: BTO:0003257 ! granulation tissue xref: MESH:A10.165.450 ! granulation tissue [Term] id: UBERON:0010263 name: obsolete embryoid body def: "Embryoid bodies are structures resembling embryos, occurring in several types of germ cell tumors." [BTO:0001718, Wikipedia:Embryoid_body] comment: Obsoled, as does not cover naturally occurring entity consider: BTO:0001718 ! embryoid body is_obsolete: true [Term] id: UBERON:0010302 name: amnioserosa def: "a single extraembryonic epithelium, which closes the germband dorsally." [doi:10.1073/pnas.0709145105] comment: Editor's notes: May be obsoleted once added to insect ontology. Coordinate with cell type in CL synonym: "amnion-serosa" RELATED [BTO:0004800] is_a: UBERON:0010303 {source="doi:10.1073/pnas.0709145105"} ! extraembryonic epithelium relationship: only_in_taxon NCBITaxon:6656 {source="doi:10.1073/pnas.0709145105", notes="Cyclorrhapha"} ! Arthropoda xref: FBbt:00000095 ! amnioserosa xref: BTO:0004800 ! amnioserosa xref: EFO:0000250 ! amnioserosa [Term] id: UBERON:0010303 ! extraembryonic epithelium name: extraembryonic epithelium synonym: "extra-embryonic epithelium" EXACT [] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000478 ! extraembryonic structure def: "An epithelium that is part of a extraembryonic structure." [OBOL:automatic] [Term] id: UBERON:0010371 name: ecto-epithelium def: "Epithelium that derives from the ectoderm. Examples: epithelium of acinus of lactiferous duct, subscapular lens epithelium, epithelium of posterior surface of cornea." [FMA:69064] synonym: "ectoderm-derived epithelium" EXACT [] intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_from UBERON:0000924 ! ectoderm xref: FMA:69064 ! ecto-epithelium [Term] id: UBERON:0010380 name: enteric nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002005 ! enteric nervous system xref: MA:0001145 ! enteric nerve def: "A nerve that is part of a enteric nervous system." [OBOL:automatic] [Term] id: UBERON:0010396 name: afferent lymphatic vessel def: "Lymphatic vessel that enters the lymph node. The afferent lymph vessels enter at all parts of the periphery of the lymph node, and after branching and forming a dense plexus in the substance of the capsule, open into the lymph sinuses of the cortical part. In doing this they lose all their coats except their endothelial lining, which is continuous with a layer of similar cells lining the lymph paths" [MP:MP] synonym: "vasa afferentia lymphoglandulae" EXACT [Wikipedia:Afferent_lymphatic_vessels] synonym: "vasa afferentia lymphoglandula" EXACT [Wikipedia:Afferent_lymphatic_vessels] is_a: UBERON:0001473 ! lymphatic vessel relationship: part_of UBERON:0000029 ! lymph node xref: MA:0000748 ! afferent lymphatic vessel xref: http://en.wikipedia.org/wiki/File:Illu_lymph_node_structure.png [Term] id: UBERON:0010397 name: efferent lymphatic vessel def: "Lymphatic vessel that exits the lymph node. The efferent lymphatic vessel commences from the lymph sinuses of the medullary portion of the lymph nodes and leave the lymph nodes either to veins or greater nodes. Efferent lymphatic vessels are also found in the thymus and spleen. This is in contrast to afferent lymphatic vessels, which are found only in lymph nodes." [MP:MP] synonym: "efferent lymphatic vessel" RELATED [Wikipedia:Efferent_lymph_vessel] synonym: "efferent lymphatic vessels" RELATED [Wikipedia:Efferent_lymph_vessel] is_a: UBERON:0001473 ! lymphatic vessel xref: MA:0000749 ! efferent lymphatic vessel [Term] id: UBERON:0010399 name: spleen trabecular artery def: "one of the branches of the splenic artery[MP]" [MP:0002354, Wikipedia:Trabecular_arteries] synonym: "trabecular artery" RELATED [] intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0001265 ! trabecula of spleen relationship: branch_of UBERON:0001194 {source="MP"} ! splenic artery xref: MA:0000759 ! spleen trabecular artery xref: ncithesaurus:Splenic_Trabecular_Artery ! splenic trabecular artery property_value: external_definition "When the splenic artery passes into the trabecula of the spleen and branches, they become known as the trabecular arteries. When these arteries then reach the white pulp, and become covered with Periarteriolar lymphoid sheaths, the name changes again to central arteries (or central arterioles). Branches of the central arteries are given to the red pulp, and these are called penicillar arteries).[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Trabecular_arteries"} xref: UMLS:C1710159 [Term] id: UBERON:0010400 name: spleen trabecular vein def: "one of the veins that feed the splenic vein" [MP:0002228, Wikipedia:Trabecular_veins] synonym: "trabecular vein" RELATED [Wikipedia:Trabecular_veins] intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001265 ! trabecula of spleen xref: MA:0000760 ! spleen trabecular vein xref: ncithesaurus:Splenic_Trabecular_Vein ! splenic trabecular vein property_value: external_definition "The trabecular veins are the largest veins inside the spleen. It drains the blood collected in the sinuses of the pulp.[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Trabecular_veins"} xref: UMLS:C1710160 [Term] id: UBERON:0010401 name: spleen central arteriole def: "A blood vessel surrounded by the periarteriolar lymphoid sheath that connects the trabecular artery to the trabecular vein" [MP:MP] synonym: "follicular arteriole" EXACT [MP:0002361] synonym: "splenic central arteriole" EXACT [MP:0002361] synonym: "central arteriole" BROAD [] is_a: UBERON:0001980 ! arteriole relationship: part_of UBERON:0001959 ! white pulp of spleen relationship: branch_of UBERON:0010399 {source="Wikipedia:Trabecular_arteries"} ! spleen trabecular artery relationship: connected_to UBERON:0010400 ! spleen trabecular vein xref: MA:0000763 ! spleen central arteriole xref: SCTID:282511007 ! Entire splenic arterioles [Term] id: UBERON:0013132 name: penicillar arteriole def: "One of the small straight arteries of the red pulp of the spleen; a branch of the spleen central artery that supplies the red pulp[WP,modified]" [UBERON:cjm, http://www.merriam-webster.com/medical/penicillus] is_a: UBERON:0001980 ! arteriole relationship: part_of UBERON:0001959 {source="FMA"} ! white pulp of spleen relationship: supplies UBERON:0001250 {source="Wikipedia:Trabecular_arteries"} ! red pulp of spleen relationship: branch_of UBERON:0010401 {source="Wikipedia:Trabecular_arteries"} ! spleen central arteriole xref: FMA:16038 ! penicillus synonym: "penicillar artery" RELATED [] synonym: "penicillus" EXACT [FMA:16038] synonym: "penicilli" EXACT PLURAL [http://www.merriam-webster.com/medical/penicilli] [Term] id: UBERON:0010402 name: epidermis suprabasal layer synonym: "suprabasal layer" BROAD [MP:0001233] synonym: "suprabasal layer of epidermis" EXACT [] synonym: "suprabasal cell layer of skin" EXACT [] is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0001003 ! epidermis relationship: adjacent_to UBERON:0002025 ! stratum basale of epidermis xref: MA:0000808 ! epidermis suprabasal layer [Term] id: UBERON:0010403 name: cortical marginal zone def: "developing superficial cortical layer located just under the pia matter." [MP:MP] comment: TODO; add other marginal zones; determine correct developmental relationships synonym: "MZ" EXACT [MP:0000792] synonym: "cortical marginal zone" EXACT [MP:0000792] synonym: "brain marginal zone" BROAD [MA:0000812] is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0002301 ! layer of neocortex relationship: adjacent_to UBERON:0002361 ! pia mater xref: MA:0000812 ! brain marginal zone [Term] id: UBERON:0010405 name: spinal cord lateral motor column def: "Column of motor neurons which innervate muscles in the limb; motor neurons in the lateral motor column are further organized into pools, each of which innervates a specific muscle in the limb" [MP:MP] is_a: UBERON:0000073 ! regional part of nervous system relationship: part_of UBERON:0002240 ! spinal cord xref: MA:0001129 ! spinal cord lateral motor column [Term] id: UBERON:0010406 name: cholinergic enteric nerve def: "nerve fibers that utilize acetylcholine as a neurotransmitter to the intestinal system" [MP:0001049] is_a: UBERON:0010380 ! enteric nerve relationship: overlaps CL:0000108 ! cholinergic neuron xref: MA:0001146 ! cholinergic enteric nerve [Term] id: UBERON:0003386 name: smooth muscle of eye def: "A portion of smooth muscle tissue that is part of a eye [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:18807 ! smooth muscle of eye xref: MA:0001268 ! ocular smooth muscle synonym: "ocular smooth muscle" EXACT [MA:0001268] intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0010408 name: ocular angle artery def: "The angular artery is the terminal part of the facial artery; it ascends to the medial angle of the eye's orbit, imbedded in the fibers of the angular head of the Quadratus labii superioris, and accompanied by the angular vein." [MP:MP] is_a: UBERON:0001637 ! artery relationship: branch_of UBERON:0001612 ! facial artery synonym: "angular artery" EXACT [FMA:49583] xref: FMA:49583 ! angular artery xref: MA:0002010 ! ocular angle artery xref: ncithesaurus:Angular_Artery ! angular artery xref: SCTID:145238006 ! Entire angular artery xref: UMLS:C0226116 [Term] id: UBERON:0010409 name: eye surface is_a: UBERON:0003102 ! surface structure relationship: part_of UBERON:0000019 ! camera-type eye xref: MA:0002486 ! eye surface [Term] id: UBERON:0010410 name: inguinal fat pad def: "encapsulated adipose tissue found in the groin" [MGI:csmith] intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0008337 ! inguinal part of abdomen xref: MA:0002548 ! inguinal fat pad [Term] id: UBERON:0010411 name: retroperitoneal fat pad def: "encapsulated adipose tissue found on the dorsal side of the peritoneum" [MGI:csmith] intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0002358 ! peritoneum relationship: located_in UBERON:0003693 ! retroperitoneal space xref: MA:0002549 ! retroperitoneal fat pad [Term] id: UBERON:0010412 name: epididymal fat pad def: "encapsulated adipose tissue associated with the epididymis" [MGI:rbabiuk, MGI:csmith] synonym: "periepididymal fat pad" EXACT [MP:0009288] intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0001301 ! epididymis xref: MA:0002550 ! epididymal fat pad [Term] id: UBERON:0010413 name: parametrial fat pad def: "encapsulated adipose tissue associated with the extension of the subserous coat of the uterus laterally between the layers of the broad ligament" [MGI:csmith] synonym: "parametrial fat depot" EXACT [MP:0009301] intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0010391 ! parametrium xref: MA:0002953 ! parametrial fat pad [Term] id: UBERON:0010414 name: omental fat pad def: "encapsulated adipose tissue associated with the fold of peritoneal tissue that extends from the stomach to the posterior abdominal wall after associating with the transverse colon" [MP:MP] synonym: "omental fat depot" EXACT [MP:0010044] intersection_of: UBERON:0003427 ! abdominal fat pad intersection_of: part_of UBERON:0003688 ! omentum xref: MA:0002956 ! omental fat pad [Term] id: UBERON:0012282 ! mammary fat pad name: mammary fat pad def: "encapsulated adipose tissue associated with the mammary gland" [MGI:csmith] intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0001911 ! mammary gland [Term] id: UBERON:0012283 name: abnormal femoral fat pad morphology def: "encapsulated adipose tissue associated with the femur" [MP:0008905] synonym: "femoral fat depot" EXACT [MP:0008905] intersection_of: UBERON:0003916 ! fat pad intersection_of: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0010415 name: barrel cortex def: "dark-staining regions of layer four of the somatosensory cortex where somatosensory inputs from the contralateral side of the body come in from the thalamus. Barrels are found in some species of rodents and species of at least two other orders." [MP:MP] comment: The term barrel field of the primary somatosensory area refers to one of 6 subdivisions of the primary somesthetic area of the cerebral cortex in the mouse ( Dong-2004 ) and the rat ( Swanson-2004 ). The other five are the lower limb of the primary somatosensory area, the mouth of the primary somatosensory area, the nose of the primary somatosensory area, the trunk of the primary somatosensory area and the upper limb of the primary somatosensory area. -- http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=2703 synonym: "primary somatosensory area, barrel field" RELATED [ABA:SSp-bfd] is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0008933 ! primary somatosensory cortex relationship: only_in_taxon NCBITaxon:9989 ! Rodenti xref: MA:0002712 ! barrel cortex xref: ABA:SSp-bfd ! Primary somatosensory area, barrel field [Term] id: UBERON:0001744 name: lymphoid tissue def: "Portion of connective tissue with various types of white blood cells enmeshed in it, most numerous being the lymphocytes[WP]." [Wikipedia:Lymphoid_tissue] comment: This class was created automatically from a combination of ontologies subset: uberon_slim synonym: "lymphatic tissue" EXACT [] synonym: "lymphocytic tissue" EXACT [] xref: BTO:0000753 xref: FMA:55220 ! Lymphoid tissue xref: GAID:342 ! lymphoid tissue xref: MA:0002436 ! lymphoid tissue xref: ncithesaurus:Lymphoid_Tissue ! Lymphoid Tissue xref: galen:LymphoidTissue ! lymphoid tissue xref: MESH:A10.549 ! lymphoid tissue is_a: UBERON:0000479 ! portion of tissue relationship: part_of UBERON:0002193 ! hemolymphoid system relationship: part_of UBERON:0002465 ! lymphoid system relationship: only_in_taxon NCBITaxon:7742 {source="NBK27108"} ! Vertebrata relationship: dubious_for_taxon NCBITaxon:7776 {source="NBK27108", notes="lampreys lack organized lymphoid tissue"} ! Gnathostomata xref: SCTID:181768009 ! Lymphatic tissue xref: UMLS:C0024296 [Term] id: UBERON:0000444 name: lymphoid follicle def: "." [http://purl.obolibrary.org/obo/uberon/tracker/6, http://purl.obolibrary.org/obo/uberon/tracker/7] comment: introducing part_of to 'cortex of lymph node' as in issue 7 introduces equivalencies; the part_of has instead been added to 'lymph node follicle' synonym: "lymphoid nodule" EXACT [FMA:55222] synonym: "nodular lymphoid tissue" EXACT [FMA:55222] synonym: "folliculus lymphaticus" RELATED [BTO:0002684] synonym: "lymphatic follicle" RELATED [BTO:0002684] synonym: "lymphatic nodule" RELATED [BTO:0002684] synonym: "nodulus lymphaticus" RELATED [BTO:0002684] synonym: "nodulus lymphoideus" RELATED [BTO:0002684] xref: FMA:55222 ! Nodular lymphoid tissue xref: ncithesaurus:Lymphoid_Follicle ! Lymphoid Follicle xref: BTO:0002684 ! lymphoid follicle xref: SCTID:64626006 ! Lymphoid nodule (also: UBERON:0010754 'germinal center') is_a: UBERON:0001744 {source="FMA"} ! lymphoid tissue xref: UMLS:C0229654 [Term] id: UBERON:0010422 ! primary nodular lymphoid tissue name: primary nodular lymphoid tissue def: "A lymphoid follicle containing naive B cells" [CL:tm] comment: Location notes: The cortex of lymph nodes, the white pulp of spleen, and mucosa associated lymphoid tissue all have these primary follicles synonym: "primary follicle" RELATED [] synonym: "primary lymphoid follicle" EXACT [] synonym: "primary lymphoid nodule" EXACT [FMA:55223] is_a: UBERON:0000444 {source="FMA"} ! lymphoid follicle relationship: has_part CL:0000788 {source="CL:tm"} ! naive B cell xref: FMA:55223 ! primary nodular lymphoid tissue [Term] id: UBERON:0001745 name: secondary nodular lymphoid tissue def: "A lymphoid follicle that contains a germinal center." [CL:tm] subset: uberon_slim synonym: "peripheral lymphoid tissue" EXACT [] synonym: "secondary lymphoid nodule" EXACT [] synonym: "secondary lymphoid tissue" EXACT [] xref: FMA:55224 ! Secondary nodular lymphoid tissue xref: GAID:946 ! germinal center xref: http://upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Keimzentrum.jpg/200px-Keimzentrum.jpg intersection_of: UBERON:0000444 ! lymphoid follicle intersection_of: has_part UBERON:0010754 ! germinal center relationship: site_of GO:0042100 ! B cell proliferation relationship: develops_from UBERON:0010422 ! primary nodular lymphoid tissue [Term] id: UBERON:0010754 ! germinal center name: germinal center def: "A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center." [UBERON:cjm, CL:tm, Wikipedia:Germinal_center] comment: A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO] synonym: "central zone of follice" EXACT [CL:tm] synonym: "light zone of follicle" EXACT [CL:tm] synonym: "reaction center of follicle" EXACT [CL:tm] synonym: "nodule" RELATED [CL:tm] synonym: "lymhpoid nodule" RELATED [CL:tm] is_a: UBERON:0001744 ! lymphoid tissue relationship: part_of UBERON:0001745 ! secondary nodular lymphoid tissue xref: BTO:0003671 ! germinal center (also: UBERON:0009039 'lymph node germinal center') xref: EV:0100051 ! germinal center xref: ncithesaurus:Germinal_Center ! Germinal Center xref: MESH:A10.549.250 ! germinal center xref: EV:0100051 ! germinal center xref: SCTID:64626006 ! Lymphoid nodule (also: UBERON:0000444 'lymphoid follicle') xref: http://upload.wikimedia.org/wikipedia/commons/6/60/Germinal_center.svg xref: UMLS:C0282491 [Term] id: UBERON:0010755 ! secondary follicle corona name: secondary follicle corona def: "The part of the secondary follicle that surrounds the germinal center." [UBERON:cjm, CL:tm] comment: Editor's note: consider making terminology consistent amongst subclasses - see http://purl.obolibrary.org/obo/uberon/tracker/7 synonym: "peripheral zone of follicle" EXACT [CL:tm] synonym: "dark zone of follicle" EXACT [CL:tm] synonym: "inactive zone of follicle" EXACT [CL:tm] synonym: "B cell corona" RELATED [] synonym: "mantle zone" RELATED [] intersection_of: UBERON:0001744 ! lymphoid tissue intersection_of: part_of UBERON:0001745 ! secondary nodular lymphoid tissue intersection_of: surrounds UBERON:0010754 ! germinal center xref: ncithesaurus:Mantle_Zone ! mantle zone xref: UMLS:C1512987 [Term] id: UBERON:0010394 ! lymphocyte domain name: lymphocyte domain comment: todo - check is_a: UBERON:0000477 ! anatomical cluster relationship: has_part CL:0000542 ! lymphocyte [Term] id: UBERON:0010393 ! T cell domain name: T cell domain comment: todo - check intersection_of: UBERON:0010394 ! lymphocyte domain intersection_of: has_part CL:0000084 ! T cell [Term] id: UBERON:0010392 name: B cell domain comment: todo - check is_a: UBERON:0010394 ! lymphocyte domain [Term] id: UBERON:0010748 name: lymph node follicle synonym: "follicle of lymph node" EXACT [] intersection_of: UBERON:0000444 ! lymphoid follicle intersection_of: part_of UBERON:0000029 ! lymph node relationship: part_of UBERON:0002006 {source="MP-def", notes="issues/7"} ! cortex of lymph node xref: MA:0000742 ! lymph node follicle def: "A lymphoid follicle that is part of a lymph node." [OBOL:automatic] [Term] id: UBERON:0010395 ! lymph node primary follicle name: lymph node primary follicle def: "An unstimulated network of follicular dendritic cells and small resting B cells in the lymph node cortex." [MP:0002345, http://purl.obolibrary.org/obo/uberon/tracker/6] synonym: "primary follicle of lymph node" EXACT [] intersection_of: UBERON:0010422 ! primary nodular lymphoid tissue intersection_of: part_of UBERON:0000029 ! lymph node xref: MA:0000743 ! lymph node primary follicle [Term] id: UBERON:0010753 ! lymph node secondary follicle name: lymph node secondary follicle def: "A secondary follicle that is located in a lymph node" [CL:tm] is_a: UBERON:0010748 {source="MA"} ! lymph node follicle intersection_of: UBERON:0001745 ! secondary nodular lymphoid tissue intersection_of: part_of UBERON:0000029 ! lymph node relationship: develops_from UBERON:0010395 ! lymph node primary follicle xref: MA:0000744 ! lymph node secondary follicle [Term] id: UBERON:0009039 name: lymph node germinal center def: "A germinal center that is located in a lymph node" [CL:tm] intersection_of: UBERON:0010754 ! germinal center intersection_of: part_of UBERON:0000029 ! lymph node relationship: part_of UBERON:0010753 {source="MA"} ! lymph node secondary follicle synonym: "germinal center" BROAD [BTO:0003671] synonym: "lymph node nodule" RELATED [] synonym: "lymph node central zone" RELATED [] synonym: "lymph node light zone" RELATED [] synonym: "lymph node activated zone" RELATED [] xref: SCTID:327147000 ! Entire germinal center of lymph node xref: MA:0002989 ! lymph node germinal center xref: BTO:0003671 ! germinal center (also: UBERON:0010754 'germinal center') xref: ncithesaurus:Lymph_Node_Germinal_Center ! Lymph Node Germinal Center [Term] id: UBERON:0010420 name: lymph node follicular corona def: "A part of the secondary follicle in which naive B cells reside along with some helper T cells, macrophages and follicular dendritic cells; these are displaced by the expanding germinal centre and form a 'mantle' around it" [MP:MP, http://purl.obolibrary.org/obo/uberon/tracker/7] synonym: "lymph node follicular mantle" EXACT [MA:0002990] synonym: "lymph node peripheral zone" EXACT [CL:tm] synonym: "lymph node dark zone" EXACT [CL:tm] synonym: "lymph node inactive zone" EXACT [CL:tm] synonym: "lymph node B cell corona" EXACT [CL:tm] intersection_of: UBERON:0010755 ! secondary follicle corona intersection_of: part_of UBERON:0000029 ! lymph node relationship: surrounds UBERON:0009039 ! lymph node germinal center relationship: part_of UBERON:0010753 {source="MA"} ! lymph node secondary follicle xref: MA:0002990 ! lymph node follicular mantle [Term] id: UBERON:0010416 name: lymph node B cell domain def: "A part of the lymph node cortex in which B lymphocytes home to primary follicles to survey follicular dendritic cells (FDCs); antigen stimulated B cells proliferate and differentiate within the follicles forming distinctive germinal centers" [MP:MP] synonym: "lymph node B cell dependent cortex" EXACT [MP:0002344] synonym: "lymph node B-cell domain" EXACT [MP:0002344] synonym: "nodular lymph node cortex" EXACT [MP:0002344] intersection_of: UBERON:0010392 ! B cell domain intersection_of: part_of UBERON:0000029 ! lymph node relationship: part_of UBERON:0002006 {source="MP"} ! cortex of lymph node xref: MA:0002851 ! lymph node B cell domain [Term] id: UBERON:0010417 name: lymph node T cell domain def: "The paracortex and interfollicular cortex of the lymph node in which T lymphocytes home to survey dendritic cells" [MP:0002347] synonym: "lymph node T cell dependent paracortex" EXACT [MP:0002347] synonym: "lymph node T-cell domain" EXACT [MP:0002347] synonym: "lymph node deep cortex" EXACT [MP:0002347] synonym: "lymph node T zone" EXACT [] synonym: "T zone of lymph node" EXACT [] synonym: "T cell zone of lymph node" EXACT [] intersection_of: UBERON:0010393 ! T cell domain intersection_of: part_of UBERON:0000029 ! lymph node relationship: part_of UBERON:0002006 {source="MP"} ! cortex of lymph node xref: MA:0002852 ! lymph node T cell domain xref: SCTID:326870003 ! Entire T zone of lymph node [Term] id: UBERON:0010423 name: primary lymphoid nodule of tonsil synonym: "lymphoid nodule of tonsil" RELATED [FMA:86018] is_a: UBERON:0010422 {source="FMA"} ! primary nodular lymphoid tissue intersection_of: UBERON:0010422 ! primary nodular lymphoid tissue intersection_of: part_of UBERON:0002372 ! tonsil xref: FMA:86018 ! lymphoid nodule of tonsil def: "A primary nodular lymphoid tissue that is part of a tonsil." [OBOL:automatic] [Term] id: UBERON:0001249 alt_id: UBERON:0003969 name: spleen lymphoid follicle def: "the area of the white pulp where the affinity maturation of B cells and the generation of memory B cells and plasma cells occur" [MP:0008470, http://purl.obolibrary.org/obo/uberon/tracker/6, CL:tm] synonym: "spleen B cell follicle" EXACT [CL:tm] synonym: "splenic B cell follicle" EXACT [CL:tm] synonym: "lymphatic follicle of spleen" EXACT [FMA:15843] synonym: "lymphoid follicle of spleen" EXACT [FMA:15843] synonym: "Malpighian body" EXACT [FMA:15843] synonym: "splenic lymphatic follicle" EXACT [FMA:15843] synonym: "splenic lymphoid follicle" EXACT [] synonym: "spleen lymphoid nodule" RELATED [MA:0002672] synonym: "lymphoid nodule of spleen" EXACT [FMA:15843] synonym: "spleen lymphoid follicle" EXACT [MA:0002672] intersection_of: UBERON:0000444 ! lymphoid follicle intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0001959 {source="MA", source="CL:tm"} ! white pulp of spleen relationship: part_of UBERON:1000024 {source="FMA"} ! parenchyma of spleen relationship: part_of UBERON:0006561 {source="FMA"} ! non-lymphatic part of lymphoid system relationship: site_of GO:0002319 ! memory B cell differentiation xref: MA:0002672 ! spleen lymphoid follicle xref: ncithesaurus:Splenic_Lymphoid_Follicle ! Splenic Lymphoid Follicle xref: SCTID:35845000 ! Lymphatic follicle of spleen xref: UMLS:C1519475 [Term] id: UBERON:0004041 ! spleen primary B follicle name: spleen primary B follicle def: "the nodules of small undifferentiated B lymphocytes and follicular dendritic cells located in the spleen white pulp" [MP:0008471] comment: AO notes - FMA:15843 is classified as primary follicle so it belongs here synonym: "primary spleen B cell follicle" EXACT [CL:tm] intersection_of: UBERON:0010422 ! primary nodular lymphoid tissue intersection_of: part_of UBERON:0002106 ! spleen xref: FMA:15843 ! lymphoid nodule of spleen [Term] id: UBERON:0004042 name: spleen secondary B follicle def: "the nodules of antigen-activated, differentiating B cells, follicular dendritic cells, antigen-presenting T cells and macrophages in the spleen white pulp" [MP:0008472] synonym: "secondary spleen B cell follicle" EXACT [CL:tm] synonym: "splenic secondary B cell follicle" EXACT [MP:0008472] intersection_of: UBERON:0001745 ! secondary nodular lymphoid tissue intersection_of: part_of UBERON:0002106 ! spleen relationship: develops_from UBERON:0004041 {source="CL:tm"} ! spleen primary B follicle [Term] id: UBERON:0005196 ! spleen germinal center name: spleen germinal center def: "A germinal center that is part of the spleen. The spleen germinal center is located in a secondary B follicle in the white pulp of the spleen." [http://purl.obolibrary.org/obo/uberon/tracker/6, CL:tm] synonym: "spleen GC" EXACT [MP:0008474] synonym: "spleen follicle center" EXACT [MP:0008474] synonym: "splenic germinal center" EXACT [MP:0008474] synonym: "germinal center of spleen" EXACT [] xref: MA:0000764 ! spleen germinal center xref: ncithesaurus:Spleen_Germinal_Center ! Splenic Germinal Center intersection_of: UBERON:0010754 ! germinal center intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0004042 {source="CL:tm"} ! spleen secondary B follicle xref: UMLS:C1710156 [Term] id: UBERON:0010421 name: spleen B cell corona def: "the area of the (spleen) secondary B follicle that surrounds the germinal center and harbors the small recirculating B lymphocytes" [CL:tm, PMID:17495967, http://purl.obolibrary.org/obo/uberon/tracker/6] synonym: "B lymphocyte domain of the spleen" BROAD [] synonym: "B cell domain of the spleen" BROAD [MP:0002360] synonym: "follicle mantle" EXACT [MP:0002360] synonym: "splenic corona" BROAD [CL:tm] synonym: "lymphocytic corona" BROAD [MP:0002360, CL:tm] synonym: "spleen lymphocytic corona" EXACT [MP:0002360, CL:tm] synonym: "spleen mantle zone" RELATED [MP:0002360, CL:tm] synonym: "spleen B-cell corona" EXACT [MP:0002360] synonym: "splenic B cell corona" EXACT [MP:0002360] synonym: "spleen B cell corona" EXACT [MP:0002360] intersection_of: UBERON:0010755 ! secondary follicle corona intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0004042 {source="CL:tm"} ! spleen secondary B follicle relationship: surrounds UBERON:0005196 ! spleen germinal center [Term] id: UBERON:0001960 name: periarterial lymphatic sheath def: "the area of the spleen in which T cells surround the central arteriole" [MP:0002358] comment: AO notes: FMA distinguishes periarterial (PALS) from periarteriolar (FMA:62806) synonym: "PALS" EXACT [MP:0002358] synonym: "T cell domain of the splenic white pulp" EXACT [MP:0002358] synonym: "periarteriolar sheath" EXACT [MP:0002358] synonym: "splenic periarteriolar lymphoid sheath" RELATED [MP:0002358] synonym: "periarterial lymphoid sheath" EXACT [] synonym: "spleen periarteriolar lymphatic sheath" EXACT [] xref: FMA:62810 ! Periarterial lymphatic sheath xref: MA:0000765 ! spleen periarteriolar lymphatic sheath intersection_of: UBERON:0010393 ! T cell domain intersection_of: part_of UBERON:0001959 ! white pulp of spleen [Term] id: UBERON:0010756 name: spleen follicular dendritic cell network def: "the enmeshed group of antigen presenting cells with extensive dendritic processes in the spleen B cell follicle that present antigen to B cells during an immune response" [MP:0008473] comment: The follicular dendritic cell network is often visualized by using the monoclonal antibody FDC-M2. synonym: "FDC network" BROAD [MP:0008473] synonym: "FDCN" BROAD [MP:0008473] synonym: "spleen FDC network" EXACT [MP:0008473] synonym: "splenic follicular dendritic cell network" EXACT [MP:0008473] is_a: UBERON:0001744 ! lymphoid tissue relationship: part_of UBERON:0004042 ! spleen secondary B follicle [Term] id: UBERON:0001211 name: Peyer's patch def: "aggregations of lymphoid tissue that are usually found in the lowest portion of the small intestine ileum in humans; as such, they differentiate the ileum from the duodenum and jejunum // nodular lymphoid structures on the serosal surface of the small intestine." [Wikipedia:Peyer's_patch] comment: AO notes: FMA has [set of?] [aggregated,small] lymphoid [follice,nodule] of [colon, SI, I, etc] - Pp is a syn for Aggregated lymphoid follicle of small intestine; but MA uses Pp as covering both SI and LI. MA also includes follicle as a part. WP says duodenum and jejunum lack PPs. Taxon notes: Reptiles have accumulations of lymphocytes in their guts that may be primitive Peyer's patches (Zapata and Solas). synonym: "aggregated lymphoid follicle of intestine" RELATED [] synonym: "aggregated lymphoid nodule" RELATED [] synonym: "noduli lymphoidei aggregati intestini tenuis" EXACT LATIN [FMA:TA, FMA:76466] subset: uberon_slim xref: GAID:950 ! peyer's patch xref: MA:0000137 ! peyer's patch xref: EFO:0001381 ! Peyer's patch xref: BTO:0001784 ! Peyer's gland xref: EMAPA:19028 ! Peyer's patches xref: MESH:A10.549.598 ! peyer's patch xref: ncithesaurus:Mouse_Peyer_s_Patches ! Murine Peyer's Patches xref: ncithesaurus:Peyer_s_Patch ! peyer patch is_a: UBERON:0001962 ! gut-associated lymphoid tissue relationship: part_of UBERON:0001242 ! intestinal mucosa relationship: part_of UBERON:0000030 ! lamina propria xref: UMLS:C0031272 [Term] id: UBERON:0010386 name: peyer's patch follicle intersection_of: UBERON:0000444 ! lymphoid follicle intersection_of: part_of UBERON:0001211 ! Peyer's patch xref: MA:0000732 ! peyer's patch follicle def: "A lymphoid follicle that is part of a Peyer's patch." [OBOL:automatic] [Term] id: UBERON:0003453 name: large intestine Peyer's patch comment: Edtor notes: requires expert attention synonym: "Peyer's patch of large intestine" EXACT [OBOL:automatic] synonym: "large intestine Peyer's patch" EXACT [OBOL:automatic] xref: MA:0001550 ! large intestine peyer's patch xref: FMA:15658 ! solitary lymphoid follicle of subdivision of large intestine intersection_of: UBERON:0001211 ! Peyer's patch intersection_of: part_of UBERON:0000059 ! large intestine synonym: "solitary lymphoid follicle of subdivision of large intestine" RELATED [FMA:15658] synonym: "solitary lymphatic follicle of large intestine" RELATED [FMA:15658] def: "A Peyer's patch that is part of a large intestine." [OBOL:automatic] [Term] id: UBERON:0003454 name: small intestine Peyer's patch def: "nodular lymphoid structures on the serosal surface of the small intestine." [] comment: Editor's note: add subtypes for jejunum, ileum synonym: "aggregated lymphoid follicle of small intestine" EXACT [FMA:15054] synonym: "Peyer's patch" BROAD [FMA:15054] synonym: "Peyer's patch of small bowel" EXACT [OBOL:automatic] synonym: "Peyer's patch of small intestine" EXACT [OBOL:automatic] synonym: "small bowel Peyer's patch" EXACT [OBOL:automatic] synonym: "small intestine Peyer's patch" EXACT [OBOL:automatic] xref: MA:0001557 ! small intestine peyer's patch xref: FMA:15054 ! aggregated lymphoid follicle of small intestine intersection_of: UBERON:0001211 ! Peyer's patch intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001204 {source="ncithesaurus"} ! mucosa of small intestine xref: SCTID:38986009 ! Entire aggregated lymphoid follicle of small intestine [Term] id: UBERON:0004697 name: Peyer's patch germinal center def: "area of the Peyer's patch where B cells proliferate and differentiate into plasma cells" [MP:0002391] xref: MA:0000734 ! peyer's patch germinal center xref: ncithesaurus:Peyer_s_Patch_Germinal_Center ! peyer patch germinal center intersection_of: UBERON:0010754 ! germinal center intersection_of: part_of UBERON:0001211 ! part_of Peyer's patch relationship: site_of GO:0002317 ! plasma cell differentiation relationship: site_of GO:0042100 ! B cell proliferation xref: UMLS:C1711398 [Term] id: UBERON:0010387 name: Peyer's patch T cell area def: "the Peyer's patch area normally occupied by T lymphocytes" [MP:0002392] intersection_of: UBERON:0010393 ! T cell domain intersection_of: part_of UBERON:0001211 ! Peyer's patch [Term] id: UBERON:0010727 name: sutural bone def: "A piece of bone that is located within a suture in the cranium." [Wikipedia:Wormian_bones] synonym: "Wormian bone" EXACT [FMA:59327] is_a: UBERON:0010428 {source="FMA"} ! flat bone relationship: part_of UBERON:0003685 ! cranial suture xref: SCTID:272677004 ! Entire wormian bone xref: FMA:59327 ! sutural bone [Term] id: UBERON:0011154 name: gular region def: "Surface structure that extends from the chin covering pharynx and larynx." [] is_a: UBERON:0003102 {source="TAO"} ! surface structure relationship: part_of UBERON:0007811 ! craniocervical region xref: TAO:0002286 ! gular region property_value: external_definition "Surface structure that is the region between the chin and the isthmus. (from http://www.briancoad.com/Dictionary/introduction.htm).[TAO]" xsd:string {ontology="TAO", external_class="TAO:0002286", date_retrieved="2012-08-14", source="TAO:wd"} [Term] id: UBERON:0010854 ! skin of front of neck name: skin of front of neck synonym: "skin of throat" EXACT [] synonym: "skin of anterior neck" EXACT [FMA:23023] synonym: "skin of anterior part of neck" EXACT [FMA:23023] synonym: "skin of anterior portion of neck" EXACT [FMA:23023] intersection_of: UBERON:0001417 ! skin of neck intersection_of: part_of UBERON:0000341 ! throat relationship: part_of UBERON:0011154 ! gular region xref: FMA:23023 ! skin of front of neck xref: SCTID:181482005 ! Entire skin of anterior portion of neck def: "A skin of neck that is part of a throat." [OBOL:automatic] [Term] id: UBERON:0010855 ! skin of forelimb wing name: skin of forelimb wing intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000024 ! forelimb wing def: "A zone of skin that is part of a forelimb wing." [OBOL:automatic] [Term] id: UBERON:0011646 name: patagialis muscle subset: grouping_class is_a: UBERON:0008196 ! muscle of pectoral girdle relationship: part_of UBERON:0010856 ! patagium relationship: has_muscle_origin UBERON:0001105 ! clavicle relationship: has_muscle_insertion UBERON:0002374 ! metacarpal bone [Term] id: UBERON:0010856 ! patagium name: patagium def: "A membranous extension of skin that forms the wing material in animals such as bats. It typically comprises a number of patagial segments, stretching from the side of the body between the forelimb digits and sometimes the hindlimbs." [Wikipedia:Patagium, http://www.brown.edu/Departments/EEB/EML/background/wing_anatomy.htm, http://animals.about.com/od/zoologytermsktoz/g/patagium.htm] synonym: "patagia" RELATED PLURAL [] synonym: "flight membrane" RELATED [] is_a: UBERON:0000094 ! membrane organ relationship: part_of UBERON:0000023 ! wing [Term] id: UBERON:0010861 name: propatagium def: "In bats and pterosaurs, thin web of skin that extends from the shoulder to the wrist anterior to the upper arm and forearm, and is fixed on the neck or skull." [http://palaeos.com/vertebrates/glossary/glossaryPo.html] comment: In birds: The triangular fold of skin on leading edge of the wing[http://caiquesite.com/glossary.htm] is_a: UBERON:0010858 ! inter limb-segment region relationship: part_of UBERON:0010856 ! patagium [Term] id: UBERON:0013070 name: prepatagium def: "a roughly triangular flap of skin on the wing of a bird or pterosaur which fills the space bounded by the humerus and ulna." [http://palaeos.com/vertebrates/glossary/glossaryPo.html] is_a: UBERON:0010858 {source="UBERON"} ! inter limb-segment region relationship: part_of UBERON:0010856 {source="UBERON"} ! patagium [Term] id: UBERON:0010862 ! dactylopatagium name: dactylopatagium def: "An interdigital region that is part of a patagium." [OBOL:automatic] intersection_of: UBERON:0006012 ! interdigital region intersection_of: part_of UBERON:0010856 ! patagium [Term] id: UBERON:0010863 name: dactylopatagium brevis intersection_of: UBERON:0010862 ! dactylopatagium intersection_of: connected_to UBERON:0001463 ! manual digit 1 intersection_of: connected_to UBERON:0003622 ! manual digit 2 def: "A dactylopatagium that is connected_to a manual digit 1 and connected_to a manual digit 2." [OBOL:automatic] [Term] id: UBERON:0010864 name: dactylopatagium minus intersection_of: UBERON:0010862 ! dactylopatagium intersection_of: connected_to UBERON:0003622 ! manual digit 2 intersection_of: connected_to UBERON:0003623 ! manual digit 3 def: "A dactylopatagium that is connected_to a manual digit 2 and connected_to a manual digit 3." [OBOL:automatic] [Term] id: UBERON:0010865 name: dactylopatagium medius is_a: UBERON:0010862 ! dactylopatagium intersection_of: UBERON:0010862 ! dactylopatagium intersection_of: connected_to UBERON:0003623 ! manual digit 3 intersection_of: connected_to UBERON:0003624 ! manual digit 4 def: "A dactylopatagium that is connected_to a manual digit 3 and connected_to a manual digit 4." [OBOL:automatic] [Term] id: UBERON:0010866 name: dactylopatagium major is_a: UBERON:0010862 ! dactylopatagium intersection_of: UBERON:0010862 ! dactylopatagium intersection_of: connected_to UBERON:0003624 ! manual digit 4 intersection_of: connected_to UBERON:0003625 ! manual digit 5 def: "A dactylopatagium that is connected_to a manual digit 4 and connected_to a manual digit 5." [OBOL:automatic] [Term] id: UBERON:0010867 name: plagiopatagium def: "a flight membrane running between the body and the limb or digits.." [http://palaeos.com/vertebrates/glossary/glossaryP.html] intersection_of: UBERON:0010862 ! dactylopatagium intersection_of: connected_to UBERON:0003625 ! manual digit 5 intersection_of: connected_to UBERON:0003823 ! hindlimb zeugopod intersection_of: part_of UBERON:0010856 ! patagium [Term] id: UBERON:0010868 ! uropropatagium name: uropropatagium def: "the membrane that is stretches between the legs of bats, used for flight, and in the case of insect-eating bats, for catching prey." [Wikipedia:Interfemoral_membrane] synonym: "interfemoral membrane" EXACT [] is_a: UBERON:0010858 ! inter limb-segment region relationship: part_of UBERON:0010856 ! patagium relationship: connected_to UBERON:0003823 ! hindlimb zeugopod [Term] id: UBERON:0010869 name: calcar def: "a spur of cartilage arising from inner side of ankle and running along part of outer interfemoral membrane in bats" [Wikipedia:Calcar] comment: Function notes: to help spread the interfemoral membrane which is part of the wing membrane between the tail and the hind legs. synonym: "calcar spur" EXACT [] synonym: "calcaneum" RELATED INCONSISTENT [Wikipedia:Calcar] is_a: UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0010868 ! uropropatagium [Term] id: UBERON:0010878 name: humeral patagium is_a: UBERON:0010855 ! skin of forelimb wing [Term] id: UBERON:0010879 name: tusk def: "Elongated, continuously growing front teeth, usually but not always in pairs, that protrude well beyond the mouth of certain mammal species. They are most commonly canines, as with warthogs, pig, and walruses, or, in the case of elephants and narwhals, elongated incisors. In most tusked species both the males and the females have tusks although the males are larger. Tusks are generally curved, though the narwhal's sole tusk is straight and has a helical structure. In the elephant, the tusks were originally second incisors. Continuous growth is enabled by formative tissues in the apical openings of the roots of the teeth" [Wikipedia:Tusk] comment: Consider adding separate classes for incisor and canine tusks. E.g. narwhal tusk = left upper incisor[Kardong] is_a: UBERON:0001091 ! calcareous tooth relationship: present_in_taxon NCBITaxon:40151 ! Monodon monoceros relationship: present_in_taxon NCBITaxon:41426 ! Phacochoerus africanus relationship: present_in_taxon NCBITaxon:9705 ! Odobenidae relationship: present_in_taxon NCBITaxon:9823 ! Sus scrofa xref: SCTID:54040005 ! Tusk [Term] id: UBERON:0010880 name: gular fold def: "A transverse fold of skin across the throat (Peters 1964)." [Wikipedia:Gular_fold, Wikipedia:Gular_skin, http://sourceforge.net/tracker/?func=detail&aid=3414172&group_id=76834&atid=994764, http://imnh.isu.edu/digitalatlas/bio/glsry.htm] is_a: UBERON:0010854 ! skin of front of neck synonym: "throat sac" RELATED [Wikipedia:Gular_fold] synonym: "gular sac" RELATED [Wikipedia:Gular_fold] synonym: "gular skin" RELATED [Wikipedia:Gular_fold] xref: AAO:0010238 ! gular fold relationship: present_in_taxon NCBITaxon:9590 {notes="gular sac", source="http://en.wikipedia.org/wiki/Siamang"} ! Symphalangus syndactylus [Term] id: UBERON:0010881 name: limb bone cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: develops_into UBERON:0002428 ! limb bone relationship: part_of UBERON:0002091 ! appendicular skeleton relationship: develops_from UBERON:0010882 ! limb bone pre-cartilage condensation def: "A cartilaginous condensation that develops_into a limb bone." [OBOL:automatic] [Term] id: UBERON:0010882 name: limb bone pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: develops_into UBERON:0002428 ! limb bone relationship: part_of UBERON:0002091 ! appendicular skeleton def: "A pre-cartilage condensation that develops_into a limb bone." [OBOL:automatic] [Term] id: UBERON:0012305 name: marginal cutaneous pouch of ear def: "A fold of skin at the caudal border of the auricle." [ISBN:9783899930993] synonym: "marginal cutaneous pouch" RELATED [] synonym: "cutaneous marginal pouch" RELATED [] is_a: UBERON:0000014 ! zone of skin relationship: part_of UBERON:0001757 ! pinna [Term] id: UBERON:0010887 name: tragus def: "a small pointed eminence of the external ear, situated in front of the concha, and projecting backward over the meatus." [Wikipedia:Tragus_(ear)] comment: Taxon notes: The tragus is generally believed to play a role in vertical sound localization in bats synonym: "tragal part of pinna" EXACT [FMA:60998] is_a: UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0001757 {source="FMA"} ! pinna xref: FMA:60998 ! tragus xref: ncithesaurus:Tragus ! tragus xref: SCTID:362541003 ! Entire tragus xref: UMLS:C0229312 [Term] id: UBERON:0010888 name: obsolete seta def: "A hair-like unicellular external process of the body wall or any derivative of the latter; a hair; a bristle." [BTO:0004212] comment: Obsoleted as the term 'seta' refers to a variety of different structures. For insect chaetae, consider the arthropod anatomy ontology. synonym: "bristle" RELATED [BTO:0004212] synonym: "sensory bristle" RELATED [MIAA:0000152] synonym: "chaeta" RELATED [MIAA:0000152] is_obsolete: true consider: INSECT:0000114 consider: BTO:0004212 ! seta consider: MIAA:0000152 ! sensory bristle [Term] id: UBERON:0010898 name: gastralium def: "Dermal element that arises via intramembranous ossification and are developmentally distinct from true ribs that articulate with the vertebral column." [VSAO:0000127, Wikipedia:Gastralium] comment: These bones may have been derived from the ventral scales found in animals like rhipidistians, labyrinthodonts, and Acanthostega, and may be related to ventral elements of turtle plastrons[WP] synonym: "abdominal rib" EXACT [VSAO:curator, ISBN10:0073040584] synonym: "belly rib" EXACT [VSAO:curator] synonym: "gastralia" EXACT PLURAL [VSAO:0000127] is_a: UBERON:0008907 {source="VSAO"} ! dermal bone relationship: part_of UBERON:0006635 {source="Kardong"} ! anterior abdominal wall disjoint_from: UBERON:0002228 ! rib xref: VSAO:0000127 ! gastralium [Term] id: UBERON:0010907 name: parafibula def: "third bone of the lower leg, normally restricted to the area of the knee, in multuberculates, monotremes and some therians" [http://palaeos.com/vertebrates/glossary/glossaryP.html#P] is_a: UBERON:0005893 ! leg bone relationship: part_of UBERON:0003823 ! hindlimb zeugopod relationship: only_in_taxon NCBITaxon:40674 {source="Palaeos"} ! Mammalia [Term] id: UBERON:0010908 name: paraglossale def: "in the avian hyoid apparatus, the arrowhead-shaped bone which forms the base of the tongue" [http://palaeos.com/vertebrates/glossary/glossaryP.html#P] synonym: "paraglossale bone" EXACT [] is_a: UBERON:0001474 ! bone element relationship: part_of UBERON:0010272 ! hyoid apparatus relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0011011 name: brachioradialis def: "Brachioradialis is a muscle of the forearm that acts to flex the forearm at the elbow. It is also capable of both pronation and supination, depending on the position of the forearm; for this reason it is also called \"the beer drinker muscle. \" It is attached to the distal styloid process of the radius by way of the brachioradialis tendon, and to the lateral supracondylar ridge of the humerus." [Wikipedia:Brachioradialis] synonym: "brachioradialis muscle" RELATED [Wikipedia:Brachioradialis] xref: FMA:38485 ! brachioradialis xref: SCTID:244989009 ! Entire brachioradialis muscle is_a: UBERON:0001630 ! muscle organ relationship: part_of UBERON:0001460 ! arm relationship: innervated_by UBERON:0001492 {source="dbpedia"} ! radial nerve synonym: "musculus brachioradialis" RELATED LATIN [Wikipedia:Brachioradialis] relationship: has_muscle_insertion UBERON:0001423 {source="dbpedia", notes="Distal radius"} ! radius bone relationship: has_muscle_origin UBERON:0000976 {source="dbpedia", notes="Lateral supracondylar ridge of the humerus"} ! humerus xref: http://upload.wikimedia.org/wikipedia/commons/9/92/Brachioradialis.png [Term] id: UBERON:0011016 name: pyramidalis synonym: "pyramidalis muscle" EXACT [FMA:15568] is_a: UBERON:0002461 {source="FMA"} ! anterior abdominal wall muscle def: "The pyramidalis is a small and triangular muscle, anterior to the Rectus abdominis, and contained in the rectus sheath." [Wikipedia:Pyramidalis_muscle] synonym: "pyramidalis" RELATED [Wikipedia:Pyramidalis_muscle] xref: FMA:15568 ! pyramidalis xref: ncithesaurus:Pyramidalis ! pyramidalis synonym: "musculus pyramidalis" RELATED LATIN [Wikipedia:Pyramidalis_muscle] relationship: has_muscle_origin UBERON:0003699 {source="dbpedia", notes="pubic symphysis and pubic crest"} ! pubic symphysis xref: http://upload.wikimedia.org/wikipedia/commons/9/91/Gray397.png xref: SCTID:244950003 ! Entire pyramidalis muscle xref: UMLS:C0224374 [Term] id: UBERON:0011025 name: aryepiglotticus muscle def: "The aryepiglotticus is a muscle of the larynx running in the aryepiglottic fold from the arytenoid cartilage to the epiglottis." [Wikipedia:Aryepiglottic_muscle] synonym: "aryepiglottic" EXACT [] synonym: "aryepiglottic muscle" EXACT [] synonym: "aryepiglottus" EXACT [FEED:FEED] synonym: "aryepiglottus muscle" EXACT [FEED:FEED] synonym: "aryepiglotticus" EXACT [Wikipedia:Aryepiglottic_muscle] synonym: "ary-epiglottic part of oblique arytenoid" EXACT [FMA:46602] synonym: "aryepiglottic muscle" EXACT [FMA:46602] synonym: "pars aryepiglottica (musculus arytenoideus obliquus)" EXACT [FMA:46602] synonym: "pars aryepiglottica musculus arytenoidei obliqui" EXACT LATIN [FMA:TA] is_a: UBERON:0001568 {source="ncithesaurus"} ! muscle of larynx relationship: part_of UBERON:0008575 {source="FMA"} ! oblique arytenoid relationship: has_muscle_origin UBERON:0001740 ! arytenoid cartilage relationship: has_muscle_insertion UBERON:0000388 ! epiglottis xref: FMA:46602 ! aryepiglotticus xref: ncithesaurus:Aryepiglottic_Muscle ! aryepiglottic muscle synonym: "pars aryepiglottica musculi arytenoidei obliqui" RELATED LATIN [Wikipedia:Aryepiglottic_muscle] synonym: "musculus aryepiglotticus" RELATED LATIN [Wikipedia:Aryepiglottic_muscle] xref: http://upload.wikimedia.org/wikipedia/commons/5/52/Musculusarytenoideus.png xref: SCTID:244818009 ! Entire aryepiglottic muscle xref: UMLS:C0224177 [Term] id: UBERON:0011049 name: uterovesical pouch def: "The peritoneum over the rectum and the bladder is continued over the intestinal surface and fundus of the uterus on to its vesical surface, which it covers as far as the junction of the body and cervix uteri, and then to the bladder, forming here a second, but shallower, pouch, the vesicouterine excavation (or uterovesical pouch). The vesicouterine excavation is close to the anterior fornix of the vagina." [Wikipedia:Vesico-uterine_pouch] synonym: "excavatio vesiocuterina" RELATED [Wikipedia:Vesico-uterine_pouch] synonym: "vesicouterine" RELATED [Wikipedia:Vesico-uterine_pouch] synonym: "vesicouterine excavation" RELATED [Wikipedia:Vesico-uterine_pouch] synonym: "vesicouterine pouch" RELATED [Wikipedia:Vesico-uterine_pouch] synonym: "excavatio vesico-uterina" EXACT [FMA:14729] synonym: "excavatio vesicouterina" EXACT LATIN [FMA:TA] synonym: "vesico-uterine pouch" EXACT [FMA:14729] synonym: "vesicouterine pouch" EXACT [FMA:14729] xref: FMA:14729 ! uterovesical pouch xref: ncithesaurus:Utero-Vesical_Pouch ! utero-vesical pouch is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0002358 ! peritoneum synonym: "excavatio vesicouterina" RELATED LATIN [Wikipedia:Vesico-uterine_pouch] xref: http://upload.wikimedia.org/wikipedia/commons/5/51/WeiblichesBeckenMedian.gif xref: SCTID:249806003 ! Entire vesicouterine pouch xref: UMLS:C1519874 [Term] id: UBERON:0011146 name: silk gland def: "Any of the glands in silk-spinning insects and spiders that secrete a protein liquid that hardens into silk on exposure to air." [BTO:0001250] is_a: UBERON:0002365 {source="BTO"} ! exocrine gland intersection_of: UBERON:0002530 ! gland intersection_of: secretes UBERON:0012245 ! silk relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda xref: BTO:0001250 ! silk gland [Term] id: UBERON:0012245 ! silk name: silk def: "A protein fiber composed mainly of fibroin and produced by certain arthropods[WP,modified]." [Wikipedia:Silk] is_a: UBERON:0000463 {source="SPD"} ! portion of organism substance relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda xref: SPD:0000318 ! silk structure [Term] id: UBERON:0011147 name: Verson's gland def: "A gland found in the larvae of lepidoptera. Each gland is made of three cells: the secretory cell, the reservoir cell and the canal cell." [] is_a: UBERON:0002365 ! exocrine gland relationship: part_of UBERON:0007376 ! outer epithelial layer relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda [Term] id: UBERON:0011149 name: Marshall's gland def: "A paired hollow organ in the genito-urinary apparatus of Raja (and probably other skates and rays) whose cavity is fluid filled." [http://www.briancoad.com/Dictionary/Complete%20Dictionary.htm] synonym: "alkaline gland" RELATED [BTO:0001661] is_a: UBERON:0002365 ! exocrine gland relationship: part_of UBERON:0001008 {source="BTO"} ! excretory system relationship: only_in_taxon NCBITaxon:7858 ! Rajiformes xref: BTO:0001661 ! alkaline gland [Term] id: UBERON:0011245 name: infra-orbital canal of maxilla def: "One of the canals of the orbital surface of the maxilla, the infraorbital canal, opens just below the margin of the orbit." [Wikipedia:Infraorbital_canal] synonym: "infraorbital canal" BROAD [Wikipedia:Infraorbital_canal] synonym: "canalis infra-orbitalis" EXACT LATIN [FMA:59048] synonym: "canalis infraorbitalis" EXACT LATIN [FMA:59048] synonym: "infra-orbital canal" BROAD [FMA:59048] is_a: UBERON:0005744 {source="FMA"} ! cranial conduit xref: FMA:59048 ! infra-orbital canal [Term] id: UBERON:0011266 name: obsolete tendon of auricularis superior comment: Made obsolete as the ear muscle inserts into cartilage and aponeurosis without any intervening tendon synonym: "auricularis superior tendon" EXACT [FMA:53843] xref: FMA:53843 ! tendon of auricularis superior is_obsolete: true [Term] id: UBERON:0011771 name: obsolete larval structure def: "Anatomical structure that is part of the larva." [AAO:0000265] is_obsolete: true comment: Obsolete term in XAO - XAO:0003058 consider: AAO:0000265 ! larval structure [Term] id: UBERON:0011858 name: acinus of exocrine gland synonym: "exocrine gland acinus" EXACT [] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0002365 ! exocrine gland def: "An acinus that is part of a exocrine gland." [OBOL:automatic] [Term] id: UBERON:0011846 name: acinus of sebaceous gland synonym: "sebaceous gland acinus" EXACT [FMA:59657] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0001821 ! sebaceous gland xref: FMA:59657 ! acinus of sebaceous gland def: "An acinus that is part of a sebaceous gland." [OBOL:automatic] [Term] id: UBERON:0011847 name: acinus of parotid gland synonym: "parotid gland acinus" EXACT [FMA:59863] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0001831 ! parotid gland xref: FMA:59863 ! acinus of parotid gland xref: SCTID:46926004 ! Acinus of parotid gland def: "An acinus that is part of a parotid gland." [OBOL:automatic] [Term] id: UBERON:0011850 name: acinus of salivary gland synonym: "salivary gland acinus" EXACT [FMA:59870] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0001044 ! salivary gland xref: FMA:59870 ! acinus of salivary gland def: "An acinus that is part of a salivary gland." [OBOL:automatic] [Term] id: UBERON:0011854 name: acinus of areolar gland synonym: "areolar gland acinus" EXACT [FMA:62081] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0011827 ! areolar gland xref: FMA:62081 ! acinus of areolar gland def: "An acinus that is part of a areolar gland." [OBOL:automatic] [Term] id: UBERON:0011856 name: acinus of lactiferous gland synonym: "lactiferous gland acinus" EXACT [FMA:74438] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0001911 ! mammary gland relationship: part_of UBERON:0001912 ! lobule of lactiferous gland xref: FMA:74438 ! acinus of lactiferous gland def: "An acinus that is part of a mammary gland." [OBOL:automatic] [Term] id: UBERON:0011857 name: acinus of lacrimal gland synonym: "lacrimal gland acinus" EXACT [FMA:85250] intersection_of: UBERON:0009842 ! acinus intersection_of: part_of UBERON:0001817 ! lacrimal gland xref: FMA:85250 ! acinus of lacrimal gland def: "An acinus that is part of a lacrimal gland." [OBOL:automatic] [Term] id: UBERON:0011860 ! collagen fibril name: collagen fibril comment: Note the FMA class specifically refers to ureter // see also: UBERON:0007377 ! stratum compactum is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: composed_primarily_of GO:0005581 ! collagen xref: FMA:63212 ! collagen fibril xref: MESH:D12.776.860.300.250.300 ! fibrillar collagen xref: NIF_Subcellular:sao7547390221 ! Collagen Fibril [Term] id: UBERON:0011861 name: aorta collagen fibril def: "the connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity" [MP:0011640] intersection_of: UBERON:0011860 ! collagen fibril intersection_of: part_of UBERON:0004664 ! aorta tunica adventitia [Term] id: UBERON:0011862 name: pulmonary collagen fibril def: "the connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity" [MP:0011641] intersection_of: UBERON:0011860 ! collagen fibril intersection_of: part_of UBERON:0002048 ! lung [Term] id: UBERON:0011863 name: bone collagen fibril def: "the connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity" [MP:0011642] intersection_of: UBERON:0011860 ! collagen fibril intersection_of: part_of UBERON:0001474 ! bone element [Term] id: UBERON:0011864 name: tendon collagen fibril def: "the connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity" [MP:0011643] intersection_of: UBERON:0011860 ! collagen fibril intersection_of: part_of UBERON:0000043 ! tendon [Term] id: UBERON:0011865 name: corneal stroma collagen fibril def: "the connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity" [MP:0011650] intersection_of: UBERON:0011860 ! collagen fibril intersection_of: part_of UBERON:0001777 ! substantia propria of cornea [Term] id: UBERON:0011879 name: mesorchium def: "The testes, at an early period of fetal life, are placed at the back part of the abdominal cavity, behind the peritoneum, and each is attached by a peritoneal fold, the mesorchium, to the mesonephros." [Wikipedia:Mesorchium] is_a: UBERON:0000481 {source="AAO"} ! multi-tissue structure relationship: part_of UBERON:0003135 {source="EMAPA"} ! male reproductive organ xref: AAO:0010530 ! mesorchium xref: EMAPA:17971 ! mesorchium [Term] id: UBERON:0011959 name: glenoid labrum of scapula def: "a ring of fibrocartilage attached to the margin of the glenoid cavity of the scapula." [http://www.medilexicon.com/medicaldictionary.php?t=47475, http://en.wikipedia.org/wiki/Glenoid_labrum] comment: Consider classifying as 'annulus fibrosus' is_a: UBERON:0007844 {source="FMA"} ! cartilage element relationship: part_of UBERON:0001470 {source="FMA"} ! glenohumeral joint synonym: "labrum glenoidale scapulae" RELATED [http://www.medilexicon.com/medicaldictionary.php?t=47475] synonym: "labrum glenoidale" EXACT LATIN [] synonym: "glenoidal labrum" BROAD [] synonym: "glenoid labrum" BROAD [] synonym: "glenoidal labrum of scapula" EXACT [] synonym: "glenoidal labrum of glenohumeral joint" EXACT [] xref: FMA:23290 ! glenoid labrum of scapula xref: SCTID:182391008 ! Entire labrum glenoidale [Term] id: UBERON:0011960 name: articular capsule of glenohumeral joint def: "The articular capsule of the humerus is the articular capsule of the shoulder joint. It completely encircles the joint, being attached, above, to the circumference of the glenoid cavity beyond the glenoidal labrum; below, to the anatomical neck of the humerus, approaching nearer to the articular cartilage above than in the rest of its extent. It is thicker above and below than elsewhere, and is so remarkably loose and lax, that it has no action in keeping the bones in contact, but allows them to be separated from each other more than 2.5 cm. , an evident provision for that extreme freedom of movement which is peculiar to this articulation. It is strengthened, above, by the Supraspinatus; below, by the long head of the Triceps brachii; behind, by the tendons of the Infraspinatus and Teres minor; and in front, by the tendon of the Subscapularis.[WP,unvetted]" [Wikipedia:Articular_capsule_of_the_humerus] synonym: "articular capsule of shoulder joint" EXACT [] synonym: "capsule of shoulder joint" EXACT [FMA:34944] synonym: "fibrous capsule of glenohumeral joint" EXACT [FMA:34944] synonym: "articular capsule of humerus" EXACT [Wikipedia:Articular_capsule_of_the_humerus] intersection_of: UBERON:0001484 ! articular capsule intersection_of: part_of UBERON:0001470 ! glenohumeral joint xref: FMA:34944 ! articular capsule of glenohumeral joint xref: SCTID:361836001 ! Entire capsule of shoulder joint [Term] id: UBERON:0011961 name: articular capsule of hip joint def: "The articular capsule (capsular ligament) is strong and dense. Above, it is attached to the margin of the acetabulum 5 to 6 mm. beyond the glenoidal labrum behind; but in front, it is attached to the outer margin of the labrum, and, opposite to the notch where the margin of the cavity is deficient, it is connected to the transverse ligament, and by a few fibers to the edge of the obturator foramen. It surrounds the neck of the femur, and is attached, in front, to the intertrochanteric line; above, to the base of the neck; behind, to the neck, about 1.25 cm. above the intertrochanteric crest; below, to the lower part of the neck, close to the lesser trochanter. From its femoral attachment some of the fibers are reflected upward along the neck as longitudinal bands, termed retinacula. The capsule is much thicker at the upper and forepart of the joint, where the greatest amount of resistance is required; behind and below, it is thin and loose. It consists of two sets of fibers, circular and longitudinal. The circular fibers, zona orbicularis, are most abundant at the lower and back part of the capsule, and form a sling or collar around the neck of the femur. Anteriorly they blend with the deep surface of the iliofemoral ligament, and gain an attachment to the anterior inferior iliac spine. The longitudinal fibers are greatest in amount at the upper and front part of the capsule, where they are reinforced by distinct bands, or accessory ligaments, of which the most important is the iliofemoral ligament. The other accessory bands are known as the pubocapsular and the ischiocapsular ligaments. The external surface of the capsule is rough, covered by numerous muscles, and separated in front from the Psoas major and Iliacus by a bursa, which not infrequently communicates by a circular aperture with the cavity of the joint." [Wikipedia:Capsule_of_hip_joint] synonym: "fibrous capsule of hip joint" EXACT [FMA:42821] synonym: "capsule of hip joint" EXACT [Wikipedia:Capsule_of_hip_joint] synonym: "articular capsule" RELATED [Wikipedia:Capsule_of_hip_joint] synonym: "capsular ligament" RELATED [Wikipedia:Capsule_of_hip_joint] synonym: "capsula articularis coxae" EXACT LATIN [Wikipedia:Capsule_of_hip_joint] intersection_of: UBERON:0001484 ! articular capsule intersection_of: part_of UBERON:0001486 ! hip joint xref: FMA:42821 ! articular capsule of hip joint xref: SCTID:263382006 ! Entire capsule of hip joint [Term] id: UBERON:0011962 name: transverse tarsal joint def: "The transverse tarsal joint is formed by the articulation of the calcaneus with the cuboid, and the articulation of the talus with the navicular. The movement which takes place in this joint is more extensive than that in the other tarsal joints, and consists of a sort of rotation by means of which the foot may be slightly flexed or extended, the sole being at the same time carried medially (inverted) or laterally." [Wikipedia:Transverse_tarsal_joint] synonym: "chopart's joint" EXACT [FMA:35201] synonym: "midtarsal joint " EXACT [Wikipedia:Transverse_tarsal_joint] synonym: "articulatio tarsi transversa" EXACT [Wikipedia:Transverse_tarsal_joint] is_a: UBERON:0011139 {source="FMA"} ! synovial limb joint relationship: part_of UBERON:0002387 ! pes xref: FMA:35201 ! transverse tarsal joint xref: SCTID:182220000 ! Entire midtarsal joint [Term] id: UBERON:0011963 name: talocalcaneonavicular joint def: "The talocalcaneonavicular articulation is an arthrodial joint: the rounded head of the talus being received into the concavity formed by the posterior surface of the navicular, the anterior articular surface of the calcaneus, and the upper surface of the plantar calcaneonavicular ligament. There are two ligaments in this joint: the articular capsule and the dorsal talonavicular." [Wikipedia:Talocalcaneonavicular_articulation] synonym: "talocalcaneonavicular articulation" EXACT [Wikipedia:Talocalcaneonavicular_articulation] synonym: "articulatio talocalcaneonavicularis" EXACT LATIN [Wikipedia:Talocalcaneonavicular_articulation] intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001450 ! calcaneus intersection_of: connects UBERON:0001451 ! navicular bone of pes intersection_of: connects UBERON:0002395 ! talus relationship: part_of UBERON:0011962 {source="FMA-modified"} ! transverse tarsal joint xref: FMA:35204 ! talocalcaneonavicular joint xref: SCTID:182211009 ! Entire talocalcaneonavicular joint [Term] id: UBERON:0011964 name: calcaneocuboid joint def: "Calcaneocuboid Articulation (articulation of the calcaneus with the cuboid). The ligaments connecting the calcaneus with the cuboid are five in number, viz. , the articular capsule, the dorsal calcaneocuboid, part of the bifurcated, the long plantar, and the plantar calcaneocuboid." [Wikipedia:Calcaneocuboid_articulation] synonym: "calcaneocuboid articulation" EXACT [Wikipedia:Calcaneocuboid_articulation] synonym: "calcaneocuboidal joint" EXACT [] synonym: "articulatio calcaneocubiodea" EXACT LATIN [FMA:35207] intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001450 ! calcaneus intersection_of: connects UBERON:0001455 ! cuboid bone relationship: part_of UBERON:0011962 {source="FMA-modified"} ! transverse tarsal joint xref: FMA:35207 ! calcaneocuboid joint xref: SCTID:361866008 ! Entire calcaneocuboidal joint [Term] id: UBERON:0011965 ! saddle joint name: saddle joint def: "In a saddle joint (sellar joint, articulation by reciprocal reception) the opposing surfaces are reciprocally concave-convex." [Wikipedia:Saddle_joint] synonym: "articulation by reciprocal reception" RELATED [Wikipedia:Saddle_joint] synonym: "sellar joint" EXACT [Wikipedia:Saddle_joint] is_a: UBERON:0000982 ! skeletal joint xref: FMA:75298 ! saddle joint xref: SCTID:23059003 ! Entire sellar joint [Term] id: UBERON:0011966 name: manubriosternal joint def: "the early union, by hyaline cartilage, of the manubrium and the body of the sternum, which later becomes a symphysial type of joint." [Wikipedia:Sternal_angle, http://www.medilexicon.com/medicaldictionary.php?t=46395] synonym: "angle of louis" RELATED [Wikipedia:Sternal_angle] synonym: "angulus ludovici" RELATED [Wikipedia:Sternal_angle] synonym: "manubriosternal joint" RELATED [Wikipedia:Sternal_angle] synonym: "manubriosternal junction" RELATED [Wikipedia:Sternal_angle] synonym: "manubro-sterno junction" RELATED [Wikipedia:Sternal_angle] synonym: "angulus sterni" RELATED [Wikipedia:Sternal_angle] synonym: "angulus sternalis" RELATED [Wikipedia:Sternal_angle] synonym: "manubriosternal symphysis" EXACT [FMA:7502] is_a: UBERON:0002216 {source="FMA"} ! symphysis intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0006820 ! body of sternum intersection_of: connects UBERON:0002205 ! manubrium of sternum xref: FMA:7502 ! manubriosternal joint xref: SCTID:263312002 ! Entire manubriosternal joint [Term] id: UBERON:0011967 name: costotransverse joint def: "The facet of the tubercle of the rib forms an articulation with the adjacent transverse process of a thoracic vertebra. This is a plane type synovial joint called the costotransverse joint. This articulation is present in all but the eleventh and twelfth ribs. Ribs 1 to 10 have two joints in close proximity posteriorly; the costovertebral joints and the costotranseverse joints. This arrangement restrains the motion of the ribs allowing them to work in a parallel fashion during breathing. If a typical rib had only one joint posteriorly the resultant swivel action would allow a rib to be non-parallel with respect to the neighboring ribs making for a very inefficient respiratory mechanism. The ventral rami innervate the costotransverse joints. Therefore, therapeutic medial branch blocks are ineffectual. The ligaments of the joint are: Articular capsule Posterior costotransverse Anterior costotransverse Ligament of the neck of the rib Ligament of the tubercle of the rib" [Wikipedia:Costotransverse_joint] synonym: "costotransverse articulation" RELATED [Wikipedia:Costotransverse_joint] is_a: UBERON:0002292 {source="FMA"} ! costovertebral joint relationship: part_of UBERON:0003252 {source="FMA"} ! rib cage xref: FMA:7952 ! costotransverse joint xref: SCTID:263328007 ! Entire costotransverse joint [Term] id: UBERON:0011985 name: infraorbital sinus def: "an air-filled recess in the head of birds which lies lateral to the nasal cavity into which it opens" [http://medical-dictionary.thefreedictionary.com/infraorbital+sinus] synonym: "sinus infraorbitalis" EXACT LATIN [] is_a: UBERON:0001825 ! paranasal sinus relationship: only_in_taxon NCBITaxon:8782 ! Aves [Term] id: UBERON:0011986 name: mucosa of infraorbital sinus synonym: "infraorbital sinus mucosa" EXACT [OBOL:automatic] intersection_of: UBERON:0000344 ! mucosa intersection_of: adjacent_to UBERON:0011985 def: "A mucosa that adjacent_to a infraorbital sinus." [OBOL:automatic] [Term] id: UBERON:0012116 ! nutrient foramen conduit name: nutrient foramen conduit def: "any of the passages admitting nutrient vessels to the medullary cavity of bone" [http://medical-dictionary.thefreedictionary.com/nutrient+foramen] is_a: UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0001474 ! bone element relationship: connected_to UBERON:0002371 ! bone marrow [Term] id: UBERON:0012117 name: lumen of nutrient foramen intersection_of: UBERON:0000464 ! anatomical space intersection_of: enclosed_by UBERON:0012116 ! nutrient foramen conduit relationship: part_of UBERON:0012116 ! nutrient foramen conduit relationship: connected_to UBERON:0002484 ! bone marrow cavity xref: FMA:75304 ! nutrient foramen xref: SCTID:29288001 ! Nutrient foramen synonym: "nutrient foramen" EXACT [FMA:75304] synonym: "nutrient foramina" EXACT PLURAL [] def: "An anatomical space that is part of a nutrient foramen conduit, leading to the medullary cavity of the bone." [UBERON:cjm] [Term] id: UBERON:0010175 name: nutrient foramen vein def: "a vein or veins draining a bone and emerging from a nutrient foramen." [http://www.medilexicon.com/medicaldictionary.php?t=97392] synonym: "nutrient vein" EXACT [FMA:50780] is_a: UBERON:0001638 ! vein relationship: overlaps UBERON:0001474 ! bone element xref: FMA:50780 ! nutrient vein synonym: "vena nutricia" RELATED LATIN [] [Term] id: UBERON:0010176 name: nutrient foramen artery def: "The medullary or nutrient artery, usually accompanied by one or two veins, sends branches upward and downward to the bone marrow, which ramify in the medullary membrane, and give twigs to the adjoining canals." [Wikipedia:Nutrient_artery] is_a: UBERON:0004573 {source="FMA"} ! systemic artery relationship: overlaps UBERON:0001474 ! bone element synonym: "nutrient artery" EXACT [FMA:50779] xref: FMA:50779 ! nutrient artery xref: SCTID:337318006 ! Entire nutrient artery xref: ncithesaurus:Nutrient_Artery ! nutrient artery synonym: "aretria nutricia" RELATED LATIN [] synonym: "a. nutricia" RELATED LATIN [Wikipedia:Nutrient_artery] synonym: "a. nutriens" RELATED LATIN [Wikipedia:Nutrient_artery] xref: UMLS:C0278431 [Term] id: UBERON:0012168 name: umbilical cord blood def: "blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]." [Wikipedia:Cord_blood] comment: Cord blood is collected because it contains stem cells, which can be used to treat hematopoietic and genetic disorders.[WP] synonym: "cord blood" RELATED [BTO:0004053] synonym: "fetal blood" RELATED [MESH:A12.207.152.200] synonym: "umbilical cord blood" RELATED [MESH:A12.207.152.200] intersection_of: UBERON:0000178 ! blood intersection_of: located_in UBERON:0001310 ! umbilical artery relationship: part_of UBERON:0000323 ! late embryo xref: BTO:0004053 ! umbilical cord blood xref: EFO:0001942 ! umbilical cord blood xref: MESH:A12.207.152.200 ! fetal blood xref: CALOHA:TS-1079 ! Umbilical cord blood [Term] id: UBERON:0012177 name: skin apocrine gland is_a: UBERON:0002419 {source="MA"} ! skin gland intersection_of: UBERON:0008974 ! apocrine gland intersection_of: part_of UBERON:0002097 ! skin of body xref: MA:0000147 ! skin apocrine gland def: "An apocrine gland that is part of a skin of body." [OBOL:automatic] [Term] id: UBERON:0012179 name: bone of pelvis comment: In MA, this is the superclass of the 3 innominate elements (pelvic girdle bones) and caudal and sacral vertebrae. This class is included to ensure consistency across anatomical ontologies is_a: UBERON:0003828 {source="MA"} ! abdominal segment bone relationship: part_of UBERON:0002355 {source="MA"} ! pelvis xref: MA:0000532 ! pelvis bone [Term] id: UBERON:0012180 name: head or neck skin xref: ncithesaurus:Skin_of_the_Scalp_and_Neck intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0007811 ! craniocervical region xref: MA:0000574 ! head or neck skin def: "A zone of skin that is part of a craniocervical region." [OBOL:automatic] xref: UMLS:C1522650 [Term] id: UBERON:0012181 name: tonsil crypt def: "Tonsils consist of an extensive system of crypts, which result in a large internal surface. The tonsils contain four lymphoid compartments that influence immune functions, namely the reticular crypt epithelium, the extrafollicular area, the mantle zones of lymphoid follicles, and the follicular germinal centers. In human palatine tonsils, the very first part exposed to the outside environment is tonsillar epithelium." [Wikipedia:Tonsillar_crypts] xref: ncithesaurus:Tonsillar_Crypt is_a: UBERON:0000483 {source="cjm"} ! epithelium relationship: part_of UBERON:0002372 {source="MA"} ! tonsil xref: MA:0000777 ! tonsil crypt xref: FMA:55044 ! tonsillar crypt synonym: "tonsillar crypt" EXACT [FMA:55044] synonym: "cryptae tonsillares" EXACT LATIN [Wikipedia:Tonsillar_crypts] xref: SCTID:143723007 ! Entire tonsillar crypt xref: UMLS:C0229876 [Term] id: UBERON:0012184 name: obsolete tunica vasculosa plexus def: "." [https://sourceforge.net/tracker/?func=detail&aid=3580301&group_id=76834&atid=1205376] comment: obsolete term deriving from MA to NCITA mappings. is_obsolete: true ! in hyaloid cavity in MA, testes in NCITA consider: MA:0001284 ! tunica vasculosa plexus consider: ncithesaurus:Tunica_Vasculosa [Term] id: UBERON:0012186 name: ovary growing follicle xref: ncithesaurus:Growing_Follicle is_a: UBERON:0001305 {source="MA"} ! ovarian follicle xref: MA:0001708 ! ovary growing follicle xref: UMLS:C1512279 [Term] id: UBERON:0012187 name: frontal artery def: "The supratrochlear artery (or frontal artery), one of the terminal branches of the ophthalmic artery, branches off where the ophthalmic travels posterior to the trochlea." [Wikipedia:Supratrochlear_artery] synonym: "a supratrochlearis" RELATED [Wikipedia:Supratrochlear_artery] synonym: "frontal arteries" RELATED [Wikipedia:Supratrochlear_artery] synonym: "frontal artery" RELATED [Wikipedia:Supratrochlear_artery] synonym: "supratrochlear artery" EXACT [FMA:50025] xref: ncithesaurus:Frontal_Artery is_a: UBERON:0001637 {source="MA"} ! artery relationship: branch_of UBERON:0001619 {source="FMA"} ! ophthalmic artery xref: MA:0001960 ! frontal artery relationship: branch_of UBERON:0001619 {source="FMA"} ! ophthalmic artery xref: FMA:50025 ! supratrochlear artery xref: SCTID:369332005 ! Entire supratrochlear artery xref: UMLS:C1708100 [Term] id: UBERON:0012198 ! intercostal space name: intercostal space def: "Space of compartment of trunk bounded by the upper and lower surfaces of two consecutive ribs." [FMA:12243, Wikipedia:Intercostal_space] xref: FMA:12243 ! intercostal space xref: SCTID:243937005 ! Entire intercostal space is_a: UBERON:0000464 ! anatomical space relationship: adjacent_to UBERON:0002228 ! rib [Term] id: UBERON:0012197 ! intercostal vein name: intercostal vein def: "The intercostal veins are a group of veins which drain the area between the ribs." [Wikipedia:Intercostal_veins] xref: EMAPA:18762 ! intercostal vein xref: SCTID:281057004 ! Entire intercostal vein intersection_of: UBERON:0001638 ! vein intersection_of: located_in UBERON:0012198 ! intercostal space [Term] id: UBERON:0012199 name: posterior intercostal vein def: "The posterior intercostal veins are veins that drain the intercostal spaces posteriorly. They run with their corresponding posterior intercostal artery on the underside of the rib, the vein superior to the artery. Each vein also gives off a dorsal branch that drains blood from the muscles of the back. There are eleven posterior intercostal veins on each side. Their patterns are variable, but they are commonly arranged as: The 1st posterior intercostal vein, supreme intercostal vein, drains into the brachiocephalic vein or the vertebral vein. The 2nd and 3rd (and often 4th) posterior intercostal veins drain into the superior intercostal vein. The remaining posterior intercostal veins drain into the azygos vein on the right, or the hemiazygos vein on the left." [Wikipedia:Posterior_intercostal_veins] synonym: "venae intercostalis posterior" EXACT LATIN [FMA:4858] xref: FMA:4858 ! posterior intercostal vein xref: SCTID:89209000 ! Entire posterior intercostal vein is_a: UBERON:0012197 ! intercostal vein [Term] id: UBERON:0012200 name: anterior intercostal vein def: "The anterior intercostal veins are the veins which drain the anterior intercostal space." [Wikipedia:Anterior_intercostal_veins] xref: FMA:12831 ! anterior intercostal vein xref: SCTID:15546000 ! Entire anterior intercostal vein is_a: UBERON:0012197 ! intercostal vein [Term] id: UBERON:0012194 ! superior intercostal vein name: superior intercostal vein def: "The superior intercostal veins are two veins that drain the 2nd, 3rd, and 4th intercostal spaces, one vein for each side of the body." [Wikipedia:Superior_intercostal_vein] xref: ncithesaurus:Superior_Intercostal_Vein is_a: UBERON:0012197 ! intercostal vein xref: MA:0002226 ! superior intercostal vein xref: UMLS:C1515066 [Term] id: UBERON:0012195 name: left superior intercostal vein is_a: UBERON:0012194 ! superior intercostal vein xref: FMA:4797 ! left superior intercostal vein xref: SCTID:27297006 ! Entire left superior intercostal vein [Term] id: UBERON:0012196 name: right superior intercostal vein is_a: UBERON:0012194 ! superior intercostal vein xref: FMA:4877 ! right superior intercostal vein xref: SCTID:80721005 ! Entire right superior intercostal vein [Term] id: UBERON:0012236 name: intercostal lymph node def: "The intercostal lymph nodes (intercostal glands ) occupy the posterior parts of the intercostal spaces, in relation to the intercostal vessels. They receive the deep lymphatics from the postero-lateral aspect of the chest; some of these vessels are interrupted by small lateral intercostal glands." [Wikipedia:Intercostal_lymph_nodes] synonym: "intercostal node" EXACT [FMA:5932] synonym: "nodus intercostale" EXACT [FMA:5932] synonym: "nodi lymphoidei intercostales" EXACT [Wikipedia:Intercostal_lymph_nodes] is_a: UBERON:0007644 {source="FMA"} ! thoracic lymph node intersection_of: UBERON:0000029 ! lymph node intersection_of: located_in UBERON:0012198 ! intercostal space xref: FMA:5932 ! intercostal lymph node xref: ncithesaurus:Intercostal_Lymph_Node ! intercostal lymph node xref: SCTID:204088001 ! Entire intercostal lymphatics xref: UMLS:C0229761 [Term] id: UBERON:0012284 name: animal hemisphere synonym: "animal pole" RELATED [] synonym: "animal pole of zygote" NARROW [] synonym: "animal pole of blastomere" NARROW [] comment: The animal pole consists of small cells that divide rapidly, in contrast with the vegetal pole below it.[WP] Note the XAO class is specific to the zygote. is_a: UBERON:0012286 ! hemisphere of embryo subset: early_development xref: AAO:0010325 xref: XAO:0000202 ! animal hemisphere [Term] id: UBERON:0012285 name: vegetal hemisphere synonym: "vegetal pole" RELATED [] synonym: "vegetal pole of zygote" NARROW [] synonym: "vegetal pole of blastomere" NARROW [] comment: The vegetal pole contains large yolky cells that divide very slowly, in contrast with the animal pole above it.[WP] is_a: UBERON:0012286 ! hemisphere of embryo subset: early_development xref: AAO:0010331 xref: XAO:0000280 ! vegetal hemisphere [Term] id: UBERON:0012286 ! hemisphere of embryo name: hemisphere of embryo def: "One of two hemispheres of the embryo at the zygote or blastula stage[WP,modified]" [Wikipedia:Polarity_in_embryogenesis, http://purl.obolibrary.org/obo/uberon/tracker/153] synonym: "pole of embryo" RELATED [] comment: Usage notes: Like many of the early_development classes in this ontology, this class requires review for its applicability across vertebrates. See the tracker item for further discussion. subset: early_development is_a: UBERON:0002050 ! embryonic structure relationship: existence_starts_during UBERON:0000106 {source="XAO"} ! zygote stage xref: http://upload.wikimedia.org/wikipedia/commons/thumb/5/5e/Oocyte_Poles.jpg/180px-Oocyte_Poles.jpg [Term] id: UBERON:0012477 name: dorsal part of neck def: "The back of the neck." [BTO:0000957] synonym: "neck back" EXACT [FMA:24189] synonym: "nucha" EXACT [FMA:24189] synonym: "nuchal region" EXACT [FMA:24189] synonym: "posterior cervical region" EXACT [FMA:24189] synonym: "posterior neck region" EXACT [FMA:24189] synonym: "posterior part of neck" EXACT [FMA:24189] synonym: "regio cervicalis posterior" EXACT [FMA:TA] synonym: "nape" BROAD [BTO:0000957] synonym: "nape of neck" EXACT [] synonym: "back of neck" EXACT [FMA:24189] is_a: UBERON:0005434 {source="FMA"} ! cervical region relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum relationship: part_of UBERON:0000974 {source="FMA"} ! neck xref: FMA:24189 ! back of neck xref: SCTID:304036007 ! Cervical region back structure xref: SCTID:182326009 ! Nape of neck xref: BTO:0000957 ! nape property_value: has_relational_adjective "nuchal" xsd:string [Term] id: UBERON:0012480 name: cloacal mucosa alt_id: UBERON:0003349 def: "A mucosa that is part of a cloaca [Automatically generated definition]." [OBOL:automatic] synonym: "cloacal mucous membrane" EXACT [] synonym: "cloaca mucosa" EXACT [] synonym: "cloaca mucosa of organ" EXACT [] synonym: "cloaca mucous membrane" EXACT [] synonym: "cloaca organ mucosa" EXACT [] synonym: "mucosa of cloaca" EXACT [] synonym: "mucosa of organ of cloaca" EXACT [] synonym: "mucous membrane of cloaca" EXACT [] synonym: "organ mucosa of cloaca" EXACT [] intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012481 name: cloacal epithelium def: "An epithelium that is part of a cloaca." [] intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012482 name: submucosa of cloaca def: "A submucosa that is part of a cloaca [Automatically generated definition]." [OBOL:automatic] synonym: "cloacal submucosa" EXACT [] synonym: "cloaca submucosa" EXACT [] intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012483 name: serosa of cloaca def: "A serous membrane that is part of a cloaca [Automatically generated definition]." [OBOL:automatic] synonym: "cloacal serosa" EXACT [] synonym: "cloaca serosa" EXACT [] synonym: "cloaca serous membrane" EXACT [] synonym: "serous membrane of cloaca" EXACT [] synonym: "visceral peritoneum of cloaca" EXACT [] intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012485 name: cloacal villus synonym: "cloacal villi" EXACT PLURAL [] is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012486 name: muscle layer of cloaca synonym: "muscularis externa of cloaca" EXACT [] synonym: "smooth muscle of cloaca" RELATED [] intersection_of: UBERON:0006660 ! muscle layer intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012520 name: forelimb epitrochlearis muscle def: "The superficial-most muscle of the anterior surface of the arm is the epitrochlearis. It has no homolog in humans." [http://biology.clc.uc.edu] synonym: "wing epitrochlearis muscle" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] is_a: UBERON:0003662 {source="BTO"} ! forelimb muscle relationship: never_in_taxon NCBITaxon:9606 ! Homo sapiens xref: BTO:0000423 ! epitrochlearis synonym: "epitrochlearis" EXACT [BTO:0000423] [Term] id: UBERON:0012615 name: umbilical smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002331 ! umbilical cord xref: BTO:0001847 ! umbilical smooth muscle [Term] id: UBERON:0012648 name: ampulla of uterine tube def: "The ampulla is the second portion of the uterine tube. It is an intermediate dilated portion, which curves over the ovary. It is the most common site of human fertilization. The word ampulla is from the Latin for flask." [Wikipedia:Ampulla_of_uterine_tube] synonym: "ampulla of fallopian tube" RELATED [Wikipedia:Ampulla_of_uterine_tube] synonym: "ampulla of the fallopian tube" RELATED [Wikipedia:Ampulla_of_uterine_tube] synonym: "ampulla of uterine tube" RELATED [BTO:0004285] synonym: "ampulla of fallopian tube" EXACT [FMA:18305] synonym: "ampulla of oviduct" EXACT [FMA:18305] synonym: "uterine tube ampulla" EXACT [FMA:18305] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0003889 {source="FMA"} ! fallopian tube xref: FMA:18305 ! ampulla of uterine tube xref: SCTID:245497001 ! Entire ampulla of fallopian tube [Term] id: UBERON:0012649 name: anococcygeus muscle def: "One of a pair of thin sheets of smooth muscle inserting on the rectum, having a tendinous origin largely on sacral vertebrae." [PMID:9071980] synonym: "anococcygeus" EXACT [MA:0001533] synonym: "AcM" RELATED ABBREVIATION [PMID:9071980] is_a: UBERON:0004231 {source="MA"} ! anal region smooth muscle relationship: attaches_to UBERON:0001052 ! rectum relationship: attaches_to UBERON:0001094 ! sacral vertebra xref: MA:0001533 ! anococcygeus xref: BTO:0005150 ! anococcygeus muscle [Term] id: UBERON:0013069 name: popliteal area def: "The popliteal fossa is a space or shallow depression located at the back of the knee-joint. The bones of the popliteal fossa are the femur and the tibia. Colloquially, it is referred to as a \"knee pit.\"" [Wikipedia:Popliteal_fossa] comment: a depression on the ventral side of the femur, between the condyles, presumably related in some fashion to the popliteal nerve and/or artery.[Palaeos] xref: FMA:22525 ! popliteal fossa synonym: "popliteal fossa" EXACT [FMA:22525] synonym: "popliteal space" RELATED [] synonym: "popliteal region" RELATED [] is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0000981 ! femur xref: http://palaeos.com/vertebrates/glossary/images/popliteal.gif xref: SCTID:362791002 ! Entire popliteal region [Term] id: UBERON:0013131 name: lobe of tail synonym: "fluke" NARROW [] synonym: "tail fluke" NARROW [] is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0012111 alt_id: UBERON:0013134 ! interdental space name: diastema def: "A space or gap between two teeth. Many species of mammals have diastemata as a normal feature, most commonly between the incisors and molars." [Wikipedia:Diastema_(dentistry)] is_a: UBERON:0000464 ! anatomical space relationship: adjacent_to UBERON:0001091 {cardinality="2"} ! calcareous tooth relationship: adjacent_to UBERON:0001091 ! calcareous tooth relationship: part_of UBERON:0003672 ! dentition relationship: part_of UBERON:0001708 ! jaw skeleton synonym: "diastemata" RELATED PLURAL [] synonym: "interdental space" EXACT [] xref: FMA:77271 ! diastema xref: SCTID:410003009 ! Entire interdental space [Term] id: UBERON:0013135 name: interdental plate def: "The interdental plate refers to the bone-filled mesial-distal region between the teeth" [Wikipedia:Interdental_plate] comment: Taxon notes: In paleobiology, the presence or absence of the interdental plate can determine the place of an animal in the evolutionary scale, and paleontologists use the interdental plate when trying to classify a new specimen. Thecodont reptiles and theropod dinosaur fossils have an interdental plate, whereas acrodont reptiles such as Sphenodontia do not.[3] Its presence in Archaeopteryx, an extinct avian, resulted in the proposal of the dinosaur-bird connection[WP] intersection_of: UBERON:0005913 ! zone of bone organ intersection_of: part_of UBERON:0012111 ! diastema relationship: part_of UBERON:0001708 ! jaw skeleton [Term] id: UBERON:0013191 name: ovarian cortex def: "The outer layer of the ovary, composed of cellular connective tissue which contains the ovarian follicles" [ncithesaurus:Ovarian_Cortex] synonym: "cortex of ovary" EXACT [FMA:18613] synonym: "cortex ovarii (zona parenchymatosa)" EXACT [FMA:18613] intersection_of: UBERON:0001851 ! cortex intersection_of: part_of UBERON:0000992 ! female gonad xref: FMA:18613 ! ovarian cortex xref: ncithesaurus:Ovarian_Cortex ! ovarian cortex xref: UMLS:C0227878 [Term] id: UBERON:0013192 name: ovarian medulla def: "The medulla of ovary (or Zona vasculosa of Waldeyer) is a highly vascular stroma in the center of the ovary. It forms from embryonic mesenchyme and contains blood vessels, lymphatic vessels, and nerves. This stroma forms the tissue of the hilum by which the ovarian ligament is attached, and through which the blood vessels enter: it does not contain any ovarian follicles." [Wikipedia:Medulla_of_ovary] comment: composed of loose connective tissue that contains blood vessels, lymph vessels and nerves[NCIT] synonym: "zona vasculosa of Waldeyer" RELATED [Wikipedia:Medulla_of_ovary] synonym: "medulla of ovary" EXACT [FMA:18616] synonym: "medulla ovarii (zona vasculosa)" EXACT [FMA:18616] intersection_of: UBERON:0000958 ! medulla intersection_of: part_of UBERON:0000992 ! female gonad xref: FMA:18616 ! ovarian medulla xref: ncithesaurus:Ovarian_Medulla ! ovarian medulla xref: UMLS:C0227879 [Term] id: UBERON:0011255 name: Eimer's organ def: "sensory organs in which the epidermis is modified to form bulbous papillae. present in many moles, and are particularly common in the star-nosed mole, which bears 30,000 of them on its unique tentacled snout. The organs are formed from a stack of epidermal cells, which is innervated by nerve processes from myelinated fibers in the dermis, which form terminal swellings just below the outer keratinized layer of epidermis. They contain a Merkel cell-neurite complex in the epidermis and a lamellated corpuscle in the dermal connective tissue." [Wikipedia:Eimer's_organ] is_a: UBERON:0000020 {source="Wikipedia"} ! sense organ relationship: has_part UBERON:0003719 ! Pacinian corpuscle relationship: has_part CL:0000242 ! Merkel cell relationship: part_of UBERON:0000412 ! dermal papilla relationship: only_in_taxon NCBITaxon:9373 ! Talpidae [Term] id: UBERON:0013206 name: nasal tentacle def: "A fleshy appendage ringing the snout of a Star-nosed mole." [Wikipedia:Star-nosed_mole] is_a: UBERON:0000021 ! cutaneous appendage relationship: has_part UBERON:0011255 ! Eimer's organ relationship: part_of UBERON:0001003 ! epidermis relationship: only_in_taxon NCBITaxon:9373 ! Talpidae relationship: confers_advantage_in ENVO:00000572 ! subterrestrial habitat [Term] id: UBERON:0013208 name: Grueneberg ganglion def: "An olfactory ganglion at the entrance of the nose of mammals that is involved in the detection of alarm pheromones and cold temperatures. The ganglion was first described by Hans GrC EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)" [] is_metadata_tag: true is_class_level: true [Typedef] id: has_no_connections_with name: has_no_connections_with def: "A is has_no_connections_with B if there are no parts of A or B that have a connection with the other." [UBERON:cjm] expand_assertion_to: "Class: EquivalentTo: (BFO_0000050 some ?X) and (UBREL_0000001 some (BFO_0000050 some ?Y)), (BFO_0000050 some ?Y) and (UBREL_0000001 some (BFO_0000050 some ?X))" [] is_metadata_tag: true is_class_level: true [Typedef] id: existence_ends_at name: existence_ends_at def: "c existence_ends_at e iff c exists_at e and not ( exists e2 : c exists_at e2 and e before e2)." [UBERON:cjm] domain: UBERON:0001062 ! anatomical entity range: UBERON:0000103 ! life cycle stage boundary [Typedef] id: existence_ends_before name: existence_ends_before def: "Relation between continuant c and occurrent s, such that every instance of c ceases to exist before s." [UBERON:cjm] domain: UBERON:0001062 ! anatomical entity range: UBERON:0000105 ! life cycle stage [Typedef] id: existence_ends_during name: existence_ends_during def: "Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely." [UBERON:cjm] comment: todo - add full axioms to bfo synonym: "ceases_to_exist_during" EXACT [] xref: BFO:0000069 ! ceases to exist during !domain: BFO:0000002 ! continuant !range: BFO:0000007 ! process transitive_over: part_of ! part_of [Typedef] id: existence_ends_with name: existence_ends_with def: "Relation between continuant and occurrent, such that c ceases to exist at the end of p." [UBERON:cjm] domain: UBERON:0001062 ! anatomical entity range: UBERON:0000105 ! life cycle stage [Typedef] id: existence_starts_after name: existence_starts_after def: "Relation between continuant c and occurrent s, such that every instance of c comes into existing after some s has completed." [UBERON:cjm] comment: disjoint_from existence_starts_during (but this cannot be expressed in OWL2) domain: UBERON:0001062 ! anatomical entity range: UBERON:0000105 ! life cycle stage holds_over_chain: existence_starts_during preceded_by [Typedef] id: existence_starts_and_ends_during name: existence_starts_and_ends_during domain: UBERON:0001062 ! anatomical entity range: UBERON:0000105 ! life cycle stage is_a: existence_ends_during ! existence_ends_during is_a: existence_starts_during ! existence_starts_during intersection_of: existence_ends_during ! existence_ends_during intersection_of: existence_starts_during ! existence_starts_during [Typedef] id: existence_starts_at name: existence_starts_at def: "c existence_starts_at e iff c exists_at e and not ( exists e2 : c exists_at e2 and e2 before e)" [UBERON:cjm] domain: UBERON:0001062 ! anatomical entity range: UBERON:0000103 ! life cycle stage boundary [Typedef] id: existence_starts_during name: existence_starts_during def: "Relation between continuant c and occurrent s, such that every instance of c comes into existing during some s." [UBERON:cjm] synonym: "begins_to_exist_during" EXACT [] xref: BFO:0000068 ! begins to exist during !domain: BFO:0000002 !range: BFO:0000007 transitive_over: part_of ! part_of [Typedef] id: existence_starts_or_ends_during name: existence_starts_or_ends_during domain: UBERON:0001062 ! anatomical entity range: UBERON:0000105 ! life cycle stage union_of: existence_ends_during ! existence_ends_during union_of: existence_starts_during ! existence_starts_during [Typedef] id: existence_starts_with name: existence_starts_with def: "Relation between continuant and occurrent, such that c comes into existence at the start of p." [UBERON:cjm] domain: UBERON:0001062 ! anatomical entity range: UBERON:0000105 ! life cycle stage holds_over_chain: existence_starts_at start_of [Typedef] id: exists_during name: exists_during !domain: UBERON:0001062 ! anatomical entity !range: UBERON:0000105 ! life cycle stage [Typedef] id: finishes name: finishes def: "Relation between occurrents, shares an end boundary with." [Allen:starts, UBERON:cjm, ZFS:finishes] synonym: "ends" EXACT [RO:0002229] xref: RO:0002229 ! ends !domain: UBERON:0000105 ! life cycle stage !range: UBERON:0000105 ! life cycle stage is_a: part_of [Typedef] id: has_end name: has_end !domain: UBERON:0000105 ! life cycle stage !range: UBERON:0000103 ! life cycle stage boundary [Typedef] id: has_part name: has_part xref: BFO:0000051 is_transitive: true inverse_of: part_of ! part_of [Typedef] id: composed_primarily_of name: composed_primarily_of def: "x composed_primarily_of y iff: more than half of the mass of x is made from parts of y" [] is_a: has_part xref: UBREL:0000002 [Typedef] id: has_quality name: has_quality xref: http://semanticscience.org/resource/SIO_000008 ! has attribute [Typedef] id: has_start name: has_start !domain: UBERON:0000105 ! life cycle stage !range: UBERON:0000103 ! life cycle stage boundary [Typedef] id: located_in name: located_in [Typedef] id: enclosed_by name: enclosed_by is_a: part_of [Typedef] id: location_of name: location_of created_by: cjm creation_date: 2009-07-30T10:22:21Z [Typedef] id: overlaps name: overlaps def: "A overlaps B if they share some part in common." [] xref: RO:0002131 !property_value: IAO:0000412 http://purl.obolibrary.org/obo/ro.owl expand_expression_to: "BFO_0000051 some (BFO_0000050 some ?Y)" [] [Typedef] id: part_of name: part_of xref: BFO:0000050 is_transitive: true [Typedef] id: has_function_in name: has_function_in [Typedef] id: immediately_preceded_by name: immediately_preceded_by def: "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" [] synonym: "directly preceded by" EXACT [] synonym: "is directly preceded by" EXACT [] synonym: "is immediately preceded by" EXACT [SIO:000251] synonym: "starts_at_end_of" EXACT [] xref: RO:0002087 ! immediately_preceded_by !domain: UBERON:0000105 ! life cycle stage !range: UBERON:0000105 ! life cycle stage is_a: preceded_by ! preceded_by xref: http://semanticscience.org/resource/SIO_000251 ! is immediately preceded by property_value: external_definition "A non-transitive temporal relation in which one process immediately precedes another process, such that there is no interval of time between the two processes[SIO:000251]." xsd:string {source="SIO:000251"} [Typedef] id: preceded_by name: preceded_by def: "X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X)" [] comment: disjoint_from part_of, but this cannot be expressed in OWL2 synonym: "is preceded by" EXACT [SIO:000249] synonym: "takes place after" EXACT [Allen:precedes] xref: BFO:0000062 is_transitive: true !domain: UBERON:0000105 ! life cycle stage !range: UBERON:0000105 ! life cycle stage [Typedef] id: secretes name: secretes [Typedef] id: site_of name: site_of def: "C site_of P iff exists species S such that P occurs_in C for all members of S. Example: bursa of Fabricius site_of B-cell differentiation." [GOC:cjm] [Typedef] id: start_of name: start_of domain: UBERON:0000103 ! life cycle stage boundary range: UBERON:0000105 ! life cycle stage [Typedef] id: starts name: starts def: "Relation between occurrents, shares a start boundary with." [Allen:starts, UBERON:cjm] !domain: UBERON:0000105 ! life cycle stage !range: UBERON:0000105 ! life cycle stage xref: RO:0002224 is_a: part_of holds_over_chain: has_start start_of [Typedef] id: surrounded_by name: surrounded_by def: "x surrounded_by y iff: x is adjacent to y and for every region r adjacent to x, r overlaps y" [UBERON:cjm] xref: RO:0002219 ! surrounded by [Typedef] id: surrounds name: surrounds def: "inverse of surrounded_by" [UBERON:cjm] inverse_of: surrounded_by xref: RO:0002221 ! surrounds [Typedef] id: connects name: connects def: "Binary relationship: z connects x if and only if there exists some y such that z connects x and y in a ternary connected_to(x,y,z) relationship." [UBERONREF:0000004] comment: Editors note: this is currently used for both structural relationships (such as between a valve and the chamber it connects) and abstract relationships (anatomical lines and the entities they connect) [Typedef] id: secreted_by name: secreted_by [Typedef] id: output_of name: output_of [Typedef] id: homologous_to name: homologous_to !is_metadata_tag: true xref: RO:0002158 ! shares ancestor with [Typedef] id: sexually_homologous_to name: sexually_homologous_to is_a: homologous_to is_metadata_tag: true [Typedef] id: serially_homologous_to name: serially_homologous_to xref: RO:0002159 [Typedef] id: in_taxon name: in taxon xref: RO:0002162 holds_over_chain: part_of in_taxon holds_over_chain: overlaps in_taxon holds_over_chain: develops_from in_taxon holds_over_chain: induced_by in_taxon holds_over_chain: has_developmental_contribution_from in_taxon holds_over_chain: attaches_to in_taxon holds_over_chain: connected_to in_taxon holds_over_chain: supplies in_taxon [Typedef] id: only_in_taxon name: only_in_taxon def: "S only_in_taxon T iff: S SubClassOf in_taxon only T" [PMID:20973947] xref: RO:0002160 !property_value: IAO:0000412 http://purl.obolibrary.org/obo/ro.owl is_a: in_taxon [Typedef] id: developmentally_replaces name: developmentally_replaces xref: RO:0002285 !property_value: IAO:0000412 http://purl.obolibrary.org/obo/ro.owl [Typedef] id: induced_by name: induced_by def: "t1 induced_by t2 if there is a process of organ induction (GO:0001759) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor tissue type T to T', where T' develops_from T." [GO:0001759] comment: sources for induced_by relationships in Uberon: Developmental Biology, Gilbert, 8th edition, figure 6.5(F) [Typedef] id: encloses name: encloses def: "x encloses y iff the convex hull formed by x contains all or the majority of y." [UBERON:cjm] [Typedef] id: never_in_taxon name: never_in_taxon def: "S never_in_taxon T iff: S SubClassOf in_taxon only not T" [PMID:20973947] is_class_level: true is_metadata_tag: true xref: RO:0002161 !property_value: IAO:0000412 http://purl.obolibrary.org/obo/ro.owl expand_assertion_to: "Class: EquivalentTo: ?X and (RO_0002162 some ?Y)" [] [Typedef] id: dubious_for_taxon name: dubious_for_taxon def: "S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T." [UBERON:cjm] comment: this relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take time to resolve. Example: metencephalon in teleost is_metadata_tag: true is_class_level: true [Typedef] id: present_in_taxon name: present_in_taxon synonym: "applicable for taxon" EXACT [] def: "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S" [UBERON:cjm] is_metadata_tag: true is_class_level: true [Typedef] id: contains name: contains [Typedef] id: tributary_of name: tributary_of comment: taken from the FMA !!! spatial [Typedef] id: proximal_to name: proximal_to def: "x proximal_to y iff x is closer to the point of attachment with the body than y." [BSPO:cjm] xref: BSPO:0000100 [Typedef] id: distal_to name: distal_to def: "x distal_to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal)." [BSPO:cjm] xref: BSPO:0000097 [Typedef] id: in_median_plane_of name: in_median_plane_of synonym: "in sagittal plane of" RELATED [] def: "X in_median_plane_of Y <=> if X lies on the median plane of Y; i.e. X overlaps o in_left_side_of Y and X overlaps o in_right_side_of Y. X is an unpaired structure" [UBERON:cjm] is_a: part_of xref: BSPO:0000127 [Typedef] id: in_lateral_side_of name: in_lateral_side_of def: "X in_lateral_side_of Y <=> if X is in_left_side_of Y or X is in_right_side_of Y. X is often, but not always a paired structure" [UBERON:cjm] is_a: part_of property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000014" xsd:anyURI xref: BSPO:0000126 [Typedef] id: in_left_side_of name: in_left_side_of def: "X left_side_of Y <=> if Y is subdivided into left and right portions, X is part_of the left portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000120 is_a: in_lateral_side_of property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000014" xsd:anyURI [Typedef] id: in_right_side_of name: in_right_side_of def: "X right_side_of Y <=> if Y is subdivided into left and right portions, X is part_of the right portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000121 is_a: in_lateral_side_of property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000014" xsd:anyURI [Typedef] id: in_superficial_part_of name: in_superficial_part_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001100 [Typedef] id: in_deep_part_of name: in_deep_part_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001101 [Typedef] id: in_posterior_side_of name: in_posterior_side_of def: "X posterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the posterior portion." [BSPO:PATO_mtg_2009] is_a: part_of xref: BSPO:0000122 [Typedef] id: posterior_part_of name: posterior_part_of def: "X posterior_part_of Y <=> X is part_of Y and X is adjacent_to the posterior boundary of Y" [UBERON:cjm] is_a: in_posterior_side_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001102 [Typedef] id: has_posterior_part name: has_posterior_part is_a: has_part inverse_of: posterior_part_of comment: to be added to BSPO xref: BSPO:0001103 [Typedef] id: in_anterior_side_of name: in_anterior_side_of def: "X anterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the anterior portion." [BSPO:PATO_mtg_2009] is_a: part_of xref: BSPO:0000123 [Typedef] id: anterior_part_of name: anterior_part_of def: "X anterior_part_of Y <=> X is part_of Y and X is adjacent_to the anterior boundary of Y" [UBERON:cjm] is_a: in_anterior_side_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001104 [Typedef] id: has_anterior_part name: has_anterior_part inverse_of: anterior_part_of is_a: has_part comment: to be added to BSPO xref: BSPO:0001105 [Typedef] id: in_proximal_side_of name: in_proximal_side_of def: "X proximal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the proximal portion." [BSPO:PATO_mtg_2009] is_a: part_of xref: BSPO:0000124 [Typedef] id: proximal_part_of name: proximal_part_of def: "X proximal_part_of Y <=> X is part_of Y and X is adjacent_to the proximal boundary of Y" [UBERON:cjm] is_a: in_proximal_side_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001106 [Typedef] id: has_proximal_part name: has_proximal_part inverse_of: proximal_part_of is_a: has_part comment: to be added to BSPO xref: BSPO:0001207 [Typedef] id: in_distal_side_of name: in_distal_side_of def: "X distal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the distal portion." [BSPO:PATO_mtg_2009] is_a: part_of inverse_of: in_proximal_side_of xref: BSPO:0000125 [Typedef] id: distal_part_of name: distal_part_of def: "X distal_part_of Y <=> X is part_of Y and X is adjacent_to the distal boundary of Y" [UBERON:cjm] is_a: in_distal_side_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001108 [Typedef] id: has_distal_part name: has_distal_part inverse_of: distal_part_of is_a: has_part comment: to be added to BSPO xref: BSPO:0001109 [Typedef] id: superficial_to name: superficial_to comment: to be added to BSPO xref: BSPO:0001110 [Typedef] id: ventral_to name: ventral_to def: "x ventral_to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly)." [BSPO:cjm] xref: BSPO:0000102 is_transitive: true [Typedef] id: dorsal_part_of name: dorsal_part_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001111 [Typedef] id: ventral_part_of name: ventral_part_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001112 [Typedef] id: preaxial_to name: preaxial_to def: "x preaxial_to y iff x is further along the preaxial-postaxial axis than y, towards the front." [http://medical-dictionary.thefreedictionary.com/preaxial] synonym: "lateral (radial) to" RELATED [] synonym: "medial (tibial) to" RELATED [] synonym: "anterior_to (developmentally)" RELATED [MA:th] is_transitive: true xref: BSPO:1000000 [Typedef] id: preaxial_part_of name: preaxial_part_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001113 [Typedef] id: postaxial_to name: postaxial_to def: "x preaxial_to y iff x is further along the preaxial-postaxial axis than y, towards the rear." [http://medical-dictionary.thefreedictionary.com/postaxial] synonym: "posterior_to (developmentally)" RELATED [MA:th] is_transitive: true comment: to be added to BSPO xref: BSPO:0001114 [Typedef] id: postaxial_part_of name: postaxial_part_of is_a: part_of comment: to be added to BSPO xref: BSPO:0001115 [Typedef] id: dorsal_to name: dorsal_to def: "x dorsal_to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly)." [BSPO:cjm] xref: BSPO:0000098 is_transitive: true inverse_of: ventral_to [Typedef] id: deep_to name: deep_to def: "Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines." [BSPO:cjm] xref: BSPO:0000107 is_transitive: true [Typedef] id: immediately_deep_to name: immediately_deep_to def: "This relation holds when both the deep_to and ajdacent_to relationship similarly hold." [BSPO:cjm] xref: BSPO:0001107 is_a: deep_to is_a: adjacent_to [Typedef] id: has_fused_element name: has_fused_element def: "x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat" [] comment: A single bone in one species may correspond to the fusion of two or more bones found as distinct elements in another. For example, tibiofibula has_fused_element tibia. A has_fused_element B does not imply that A has_part some B, rather than A has_part some B', where B' is not a subtype of B (because B is a distinct element but B' is a regional part) but has some evolutionary relationship to B. !is_metadata_tag: true !is_class_level: true [Typedef] id: channel_for name: channel for synonym: "carries" BROAD [] domain: UBERON:0004111 ! anatomical conduit range: UBERON:0000463 ! portion of organism substance [Typedef] id: channels_into name: channels_into is_transitive: true [Typedef] id: channels_from name: channels_from is_transitive: true [Typedef] id: transitively_connected_to name: transitively_connected to is_transitive: true [Typedef] id: connected_to name: connected to def: "Binary relationship: x connected_to y if and only if there exists some z such that z connects x and y in a ternary connected_to(x,y,z) relationship." [UBERONREF:0000004] comment: Connection does not imply overlaps. is_a: transitively_connected_to xref: UBREL:0000001 property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/references/reference_0000004" xsd:anyURI property_value: seeAlso http://semanticscience.org/resource/SIO_000652 ! is connected to [Typedef] id: transitively_anteriorly_connected_to name: transitively anteriorly connected to def: "." [UBERONREF:0000004] is_transitive: true [Typedef] id: anteriorly_connected_to name: anteriorly connected to def: "x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y." [UBERONREF:0000004] is_a: connected_to is_a: posterior_to is_a: transitively_anteriorly_connected_to !equivalent_to_chain: has_anterior_part connected_to [Typedef] id: posteriorly_connected_to name: posteriorly connected to def: "x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y." [UBERONREF:0000004] is_a: connected_to is_a: anterior_to !equivalent_to_chain: has_posterior_part connected_to [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to def: "." [UBERONREF:0000004] is_transitive: true [Typedef] id: proximally_connected_to name: proximally connected to def: "x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y." [UBERONREF:0000004] is_a: transitively_proximally_connected_to is_a: connected_to is_a: distal_to !equivalent_to_chain: has_proximal_part connected_to inverse_of: distally_connected_to [Typedef] id: transitively_distally_connected_to name: transitively distally connected to def: "." [UBERONREF:0000004] is_transitive: true [Typedef] id: distally_connected_to name: distally connected to def: "x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y." [UBERONREF:0000004] is_a: transitively_distally_connected_to is_a: connected_to is_a: proximal_to !equivalent_to_chain: has_distal_part connected_to inverse_of: proximally_connected_to [Typedef] id: subdivision_of name: subdivision of comment: placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B [Typedef] id: confers_advantage_in name: confers_advantage_in synonym: "adapted_for" NARROW [] comment: An experimental relation currently used to connect an anatomical structure to a habitat or environment to which that structure is well suited, adapted or provides an advantage for the organism. For example, fins to an aquatic environment. Usually this will mean that the structure is adapted for this environment, but we avoid saying this directly - primitive forms of the structure may not have evolved specifically for that environment (for example, early wings were not necessarily adapted for an aerial environment). Note also that this is a statement about the general class of structures - not every instance of a limb need confer an advantage for a terrestrial environment, e.g. if the limb is vestigial. !!! counting [Typedef] id: is_count_of name: is count of is_metadata_tag: true [Typedef] id: preceding_element_is name: preceding element is def: "A property used in conjunction with repeated_element_number to indicate an axis and directionality along that axis. If P preceding_element_is R, and P is_count_of S, and X P N, and X' P N+1, then it follows that every X R some X', and the class expression [S and R some X' and inv(R) some X] is empty (i.e. X is followed by X', with no intermediates)" [UBERON:cjm] is_metadata_tag: true [Typedef] id: repeated_element_number name: repeated element number def: "A property used to indicate the position of an element where that element is of a type that is serially repeated linearly along some axis for which a total ordering exists. The ordering may represent an ancestral condition" [UBERON:cjm] comment: The range is currently non-negative integer is_metadata_tag: true !range: xsd:nonNegativeInteger [Typedef] id: pharyngeal_arch_number name: pharyngeal arch number def: "x pharyngeal_arch_number N if and only if (i) x is a pharyngeal arch, and (ii) x is ancestrally pharyngeal arch number N in a series of pharyngeal arches repeated along a antero-posterior axis, with arch_number 1 being the mandibular arch." [UBERON:cjm] comment: Note that gill arch N = PA N-2. the term branchial_arch is ambiguous. is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0002539 ! pharyngeal arch property_value: preceding_element_is anterior_to [Typedef] id: ray_number name: ray number def: "x ray_number N if and only if (i) x is a ray, and (ii) x is ancestrally associated with ray number N in a series of phalanges repeated along a radio-ulnar or equivalent axis, with ray_number 1 being the anteriormost ray." [UBERON:cjm] comment: The correct terminology is yet to be established; in tetrapods 'ray' might mean the mereological sum of the phalanges of a manual digit plus a metatarsal bone (or equivalent for hindlimb) is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0002544 ! digit property_value: preceding_element_is preaxial_to [Typedef] id: phalanx_number name: phalanx number def: "x phalanx_number N if and only if (i) x is a phalanx, and (ii) x is phalanx number N in a series of phalanges repeated along an prixomo-distal axis, with phalanx_number 1 being the proximalmost phalanx. Note that in humans, the distalmost phalanx has phlanax_number 3, except in ray_number 1, where the distalmost has phalanx_number 2" [UBERON:cjm, Wikipedia:Phalanx_bone#Phalangeal_formula] comment: Most land mammals including humans have a 2-3-3-3-3 formula in both the hands (or paws) and feet. Primitive reptiles typically had the formula 2-3-4-4-5, and this pattern, with some modification, remained in many later reptiles and in the mammal-like reptiles. The phalangeal formula in the flippers of cetaceans (marine mammals) is 2-12-8-1 is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0003221 ! phalanx property_value: preceding_element_is proximal_to [Typedef] id: rib_number name: rib number def: "x rib_number N if and only if (i) x is a rib, and (ii) x is rib number N in a series of ribs repeated along an anterior-posterior axis, with rib_number 1 being the anteriormost rib. Note that this property counts ribs, *not* the adjoining vertebrae." [UBERON:cjm] comment: AO notes: Note that in TAO, ribs are numbered by *vertebrae*. Taxon notes: In the early tetrapods, every vertebra bore a pair of ribs, although those on the thoracic vertebrae are typically the longest. In most subsequent forms, many of these early ribs have been lost, and in living amphibians and reptiles, there is great variation in rib structure and number. For example, turtles have only eight pairs of ribs, which are developed into a bony or cartilagenous carapace and plastron, while snakes have numerous ribs running along the full length of their trunk. Frogs typically have no ribs, aside from a sacral pair, which form part of the pelvis. Mammals usually also only have distinct ribs on the thoracic vertebra, although fixed cervical ribs are also present in monotremes. In marsupials and placental mammals, the cervical and lumbar ribs are found only as tiny remnants fused to the vertebrae, where they are referred to as transverse processes. In general, the structure and number of the true ribs in humans is similar to that in other mammals. Unlike reptiles, caudal ribs are never found in mammals. is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0002228 ! rib property_value: preceding_element_is anterior_to [Typedef] id: vertebra_number name: vertebra number def: "x vertebra_number N if and only if (i) x is a vertebra, and (ii) x is vertebra number N in a series of vertebras repeated along an anterior-posterior axis, with vertebra_number 1 being the anteriormost vertebra (also known as the atlas)." [UBERON:cjm] is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0002412 ! vertebra property_value: preceding_element_is anterior_to [Typedef] id: somite_number name: somite number def: "x somite_number N if and only if (i) x is a somite, and (ii) x is somite number N in a series of somites repeated along an anterior-posterior axis, with somite_number 1 being the anteriormost somite." [UBERON:cjm] is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0002329 ! somite property_value: preceding_element_is anterior_to [Typedef] id: paired_appendage_number name: paired_appendage number def: "x paired_appendage_number N if and only if (i) x is a paired_appendage, and (ii) x is paired_appendage number N in a series of paired_appendages repeated along an anterior-posterior axis, with paired_appendage_number 1 being the anteriormost paired_appendage. In vertebrates, this is the pectoral appendage" [UBERON:cjm] is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0000026 ! appendage property_value: preceding_element_is anterior_to [Typedef] id: appendage_segment_number name: appendage segment number def: "x appendage_segment_number N if and only if (i) x is a appendage_segment, and (ii) x is appendage_segment number N in a series of appendage_segments repeated along an proximo-distal axis, with appendage_segment_number 1 being the proximalmost appendage_segment (in tetrapods this would be the stylopod, as we do not classify girdles as appendage segments)." [UBERON:cjm] comment: Examples: in dropsphila coxa=1, trochanter=2, femur=3, tibia=4, tarsal segments 1-5=5-9, pretarsus=10 is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0010758 ! appendage segment property_value: preceding_element_is proximal_to [Typedef] id: rhombomere_number name: rhombomere number def: "x rhombomere_number N if and only if (i) x is a rhombomere, and (ii) x is rhombomere number N in a series of rhombomeres repeated along an anterior-posterior axis, with rhombomere_number 1 being the anteriormost rhombomere." [UBERON:cjm] is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0001892 ! rhombomere property_value: preceding_element_is anterior_to [Typedef] id: tooth_number name: tooth number def: "x tooth_number N if and only if (i) x is a tooth, and (ii) x is ancestrally tooth number N in a series of teeth repeated along an anterior-posterior axis, typically on the lateral side of a structure such as a jaw, with tooth_number 1 being the anteriormost. Note that this count refers to the total number of teeth starting from the first, regardless of the type of tooth. If sub-systems are required for numbering within a series of teeth of the same type, consider a subproperty. For example, in a human, maxillary canine = tooth 3 of upper jaw = canine_tooth 1 of upper jaw" [] comment: see also: dental_formula is_a: repeated_element_number is_metadata_tag: true property_value: is_count_of UBERON:0001091 ! calcareous tooth property_value: preceding_element_is anterior_to [Typedef] id: dental_formula name: dental formula def: "Syntax: upper/lower = I.C.P.M / I.C.P.M. When used with generic tooth class applies to both deciduous and primary. Should also be used with a taxon property." [Wikipedia:Dentition#Dental_formula] is_metadata_tag: true !!! textual metadata [Typedef] id: external_definition name: external_definition def: "An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class." [UBERON:cjm] comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO is_metadata_tag: true xref: UBPROP:0000001 [Typedef] id: axiom_lost_from_external_ontology name: axiom_lost_from_external_ontology def: "A textual description of an axiom loss in this ontology compared to an external ontology." [UBERON:cjm] comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO is_metadata_tag: true xref: UBPROP:0000002 [Typedef] id: homology_notes name: homology_notes def: "Notes on the homology status of this class." [UBERON:cjm] comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO is_metadata_tag: true xref: UBPROP:0000003 [Typedef] id: provenance_notes name: provenance_notes def: "Notes on the provenance of this class." [UBERON:cjm] comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO is_metadata_tag: true xref: UBPROP:0000004 [Typedef] id: external_comment name: external_comment def: "An alternate comment for a class taken unmodified from an external source. Note that obo format only allows a single comment for a class, and does not provide a structured means of adding provenance info." [UBERON:cjm] comment: This annotation property may be replaced with an annotation property from an external ontology such as IAO is_metadata_tag: true xref: UBPROP:0000005 [Typedef] id: implements_design_pattern name: implements_design_pattern is_metadata_tag: true xref: UBPROP:0000006 [Typedef] id: has_relational_adjective name: has_relational_adjective comment: Used to connect a class to an adjectival form of its label. For example, a class with label 'intestine' may have a relational adjective 'intestinal'. is_metadata_tag: true xref: UBPROP:0000007 [Typedef] id: taxon_notes name: taxon_notes is_metadata_tag: true xref: UBPROP:0000008 [Typedef] id: foaf-depicted_by name: depicted_by is_metadata_tag: true xref: http://xmlns.com/foaf/0.1/depicted_by [Typedef] id: foaf-homepage name: homepage is_metadata_tag: true xref: http://xmlns.com/foaf/0.1/homepage [Typedef] id: dc-title name: title is_metadata_tag: true xref: http://purl.org/dc/elements/1.1/title [Typedef] id: dc-contributor name: contributor is_metadata_tag: true xref: http://purl.org/dc/elements/1.1/contributor [Typedef] id: dc-creator name: creator is_metadata_tag: true xref: http://purl.org/dc/elements/1.1/creator [Typedef] id: dc-publisher name: publisher is_metadata_tag: true xref: http://purl.org/dc/elements/1.1/publisher [Typedef] id: dc-description name: description is_metadata_tag: true xref: http://purl.org/dc/elements/1.1/description [Typedef] id: dc-source name: derived from resource is_metadata_tag: true xref: http://purl.org/dc/elements/1.1/source [Typedef] id: dcterms-isReferencedBy name: is referenced by is_metadata_tag: true xref: http://purl.org/dc/terms/isReferencedBy [Typedef] id: doap-GitRepository name: Git repository is_metadata_tag: true xref: http://usefulinc.com/ns/doap#GitRepository [Typedef] id: doap-SVNRepository name: SVN repository is_metadata_tag: true xref: http://usefulinc.com/ns/doap#SVNRepository [Typedef] id: doap-wiki name: wiki is_metadata_tag: true xref: http://usefulinc.com/ns/doap#wiki [Typedef] id: doap-bug-database name: bug database is_metadata_tag: true xref: http://usefulinc.com/ns/doap#bug-database [Typedef] id: seeAlso name: see also is_metadata_tag: true xref: http://www.w3.org/2000/01/rdf-schema#seeAlso [Typedef] id: example_of_usage name: example of usage is_metadata_tag: true xref: IAO:0000122