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new term: dermatologic system #53
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We already have http://purl.obolibrary.org/obo/UBERON_0002416 (integumental system), which is the skin plus various associated structures. It's not clear if the FMA class of the same name is precisely a taxonomic equivalent (they include a couple of glands, and in FMA hair counts as part of the skin directly). I'm not sure what the mucosal system as a unit would include - it's not a term that is any AOs I know of. I suspect this would be more restricted than the mereological sum of all mucosae in a body. If you want this in the short term we can add something with a loose definition subject to change. We need to do a review of the integumentary system and its precursors at some time, and we can add then. If this is intended purely for human/medical use then you might also want to consider adding to FMA |
For now, I need something to cover for sking (rashes etc) and the eye mucosa (red and itchy eyes). I didn't find any mucosal system either, and as you mention just adding all mucosa as parts to create one seems odd. I was hoping maybe somebody with more anatomical/medical knowledge in your group would be able to help. |
After consulting with Peter Robinson, I think a grouping term for skin + mucosa would be better. See for example: Note that skin in vertebrates is just epidermis+dermis, whereas integumental system is broader. |
Skin may not work in my case, as I have for example angioedema (http://en.wikipedia.org/wiki/Angioedema), which they define as "the rapid swelling (edema) of the dermis, subcutaneous tissue mucosa and submucosal tissues." - so I would need to include hypodermis in addition to skin and mucosa. |
So the mereological sum of mucosa+submucosa + integumentary system (epidermis, dermis, hypodermis plus associated adnexa)? |
(sorry for dropping the ball on this) As an example, here is how FMA defines two other systems I am looking at: Respiratory system: Organ system which consists of structures involved in respiration. [..] On 2012-09-04, at 5:08 PM, Chris Mungall wrote:
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Do you want to suggest a definition then? Following the FMA style, and including the structures above? |
Well I'd go for "organ system" a la FMA: "organ system which consists of the mucosa, submucosa and integumentary system". Maybe we could ask Peter if this makes sense to him? While this provide a fix, I don't have a definition for organ system (nor did I find a satisfactory one) On 2012-09-17, at 2:58 PM, Chris Mungall wrote:
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In the guidelines I am interested in, physicians mention the respiratory system (UBERON_0001004), the cardiovascular system (0004535) etc as those systems that can be affected for example in the case of anaphylaxis. They also mention the "dermatologic or mucosal" system, for which I can't find an UBERON term.
They include things such as rashes, angioedema, prickle sensation and red and itchy eyes in things affecting the dermatologic or mucosal system. I am not sure how to define this appropriately, and was wondering if you would be able to define/add this to UBERON?
Melanie
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