Ontology about C. elegans and other nematode phenotypes
C elegans Phenotype Ontology
C_elegans_phenotype_ontology
chris-grove
2024-04-09
Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000000
chromosome instability
Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control.
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered.
body posture abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000001
body posture variant
Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered.
WB:WBPerson557
WB:cab
The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000002
kinker
The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals.
WB:WBPerson2021
WB:WBPerson557
WB:WBPerson712
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000003
obsolete flattened locomotion path
true
Eggs are laid under conditions where egg laying is normally inhibited.
Egl c
C_elegans_phenotype_ontology
WBPhenotype:0000004
Liquid M9.
constitutive egg laying
Eggs are laid under conditions where egg laying is normally inhibited.
WB:cab
Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000005
hyperactive egg laying
Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control.
WB:cab
Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control.
Egl d
C_elegans_phenotype_ontology
WBPhenotype:0000006
egg laying defective
Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control.
WB:WBPaper00004402
WB:WBPaper00004651
WB:WBPaper00005654
WB:WBPaper00006395
WB:WBPaper00024497
WB:WBPaper00025054
WB:cab
A worm carcass is formed with retained eggs that hatch inside.
Bag
C_elegans_phenotype_ontology
WBPhenotype:0000007
bag of worms
A worm carcass is formed with retained eggs that hatch inside.
WB:cab
Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals.
anaesthetic hypersensitive
C_elegans_phenotype_ontology
WBPhenotype:0000008
anesthetic hypersensitive
Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
anaesthetic resistant
C_elegans_phenotype_ontology
WBPhenotype:0000009
anesthetic resistant
Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000010
drug hypersensitive
Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug.
C_elegans_phenotype_ontology
WBPhenotype:0000011
drug resistant
Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug.
WB:WBPerson557
Formation of dauer larvae under conditions that do not favor dauer formation.
Daf c
C_elegans_phenotype_ontology
WBPhenotype:0000012
dauer constitutive
Formation of dauer larvae under conditions that do not favor dauer formation.
WB:kmva
Failure to form dauer larvae under dauer-inducing conditions.
Daf d
C_elegans_phenotype_ontology
WBPhenotype:0000013
dauer defective
Failure to form dauer larvae under dauer-inducing conditions.
WB:kmva
Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals.
cord commissures abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000014
cord commissures variant
Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals.
WB:WBPaper00001499
WB:WBPaper00029065
WB:WBPerson712
Variations in the movement towards typically attractive chemicals.
C_elegans_phenotype_ontology
WBPhenotype:0000015
positive chemotaxis defective
Variations in the movement towards typically attractive chemicals.
WB:cab
Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals.
Hic
C_elegans_phenotype_ontology
WBPhenotype:0000016
aldicarb hypersensitive
Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
Ald R
Ric
C_elegans_phenotype_ontology
WBPhenotype:0000017
aldicarb resistant
Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000018
pharyngeal pumping increased
The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals.
WB:WBPerson712
Pharyngeal pumping motion occurs at a slower rate than control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000019
pharyngeal pumping reduced
Pharyngeal pumping motion occurs at a slower rate than control animals.
WB:WBPaper00001709
Pharyngeal pumping motion occurs at intervals that vary from control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000020
pharyngeal pumping irregular
Pharyngeal pumping motion occurs at intervals that vary from control animals.
WB:WBPaper00001709
Squat animals are dumpy as homozygotes, but roll as heterozygotes.
Sqt
C_elegans_phenotype_ontology
WBPhenotype:0000021
squat
Squat animals are dumpy as homozygotes, but roll as heterozygotes.
WB:WBPaper00000906
Animals are longer than control animals at the same developmental stage.
Lon
C_elegans_phenotype_ontology
WBPhenotype:0000022
long
Animals are longer than control animals at the same developmental stage.
WB:cab
WB:cgc31
Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000023
serotonin hypersensitive
Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000024
serotonin resistant
Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Fluid-filled blisters appear on the cuticle.
Bli
C_elegans_phenotype_ontology
WBPhenotype:0000025
blistered
Fluid-filled blisters appear on the cuticle.
WB:WBPaper00004402
WB:WBPaper00005654
WB:WBPaper00006395
WB:WBPaper00024497
WB:cab
WB:cgc31
Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva.
Lpd
C_elegans_phenotype_ontology
fat depleted
WBPhenotype:0000026
lipid depleted
Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva.
GO:0006629
WB:WBPaper00005707
WB:WBPerson712
Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control.
organism metabolism processing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000027
organism metabolism processing variant
Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control.
GO:0008152
WB:WBPerson2021
WB:WBPerson557
Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control.
RNA processing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000028
RNA processing variant
Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control.
GO:0006396
WB:WBPerson2021
Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding.
systemic RNAi abnormal
C_elegans_phenotype_ontology
Environmental RNAi defective
WBPhenotype:0000029
systemic RNAi variant
Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding.
WB:WBPaper00029209
WB:WBPaper00030758
WB:WBPerson712
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals.
growth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000030
growth variant
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals.
GO:0040007
WB:WBPerson2021
Any variation that causes a reduction in growth rate compared to control.
Gro
C_elegans_phenotype_ontology
WBPhenotype:0000031
slow growth
Any variation that causes a reduction in growth rate compared to control.
WB:WBPaper00004402
WB:WBPaper00004403
WB:WBPaper00004651
WB:WBPaper00004769
WB:WBPaper00005654
WB:WBPaper00006395
WB:WBPaper00024497
WB:WBPerson557
WB:cab
Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc.
Sck
C_elegans_phenotype_ontology
WBPhenotype:0000032
sick
Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc.
WB:WBPaper00000179
WB:WBPaper00000565
WB:WBPerson712
The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues.
WBPhenotype:0000437
heterochronic defect
developmental timing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000033
Possible XP GO:0040034.
developmental timing variant
The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues.
WB:cab
pmid:6494891
Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals.
embryonic polarity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000034
embryonic polarity variant
Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals.
WB:WBPaper00005079
WB:WBPerson2021
WB:WBPerson712
Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals.
larval body morphology abnormal
C_elegans_phenotype_ontology
larval morphology abnormal
WBPhenotype:0000035
larval body morphology variant
Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals.
adult body morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000036
adult body morphology variant
Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals.
egg morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000037
egg morphology variant
Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals.
WB:WBPaper00001075
WB:WBPerson2021
The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
Rup
C_elegans_phenotype_ontology
burst vulva
gonad eversion
gonad exploded through vulva
rupture through vulva
WBPhenotype:0000038
exploded through vulva
The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
WB:WBPaper00027633
WB:WBPaper00031094
WB:WBPerson712
Adult life span is either longer or shorter than typical of control animals.
Age
life span abnormal
life span variant
C_elegans_phenotype_ontology
longevity abnormal
WBPhenotype:0000039
life span phenotype
Adult life span is either longer or shorter than typical of control animals.
GO:0008340
WB:WBPaper00005863
WB:WBPaper00026717
WB:WBPerson557
WB:cab
Embryos fail to divide and arrest as one-cell embryos.
Emb
Ocs
C_elegans_phenotype_ontology
catastrophic one cell arrest
WBPhenotype:0000040
one cell arrest early emb
Embryos fail to divide and arrest as one-cell embryos.
WB:cab
WB:cgc5599
catastrophic one cell arrest
WB:cgc5599
Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control.
osmotic integrity abnormal
C_elegans_phenotype_ontology
osmoregulation variant
WBPhenotype:0000041
osmotic integrity variant
Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control.
GO:0030104
WB:WBPerson2021
The progression through stages between fertilization to hatching are temporally retarded.
Sle
C_elegans_phenotype_ontology
WBPhenotype:0000042
slow embryonic development
The progression through stages between fertilization to hatching are temporally retarded.
WB:WBPerson712
Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals.
general pace of development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000043
general pace of development variant
Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Egg is smaller or larger compared to eggs of control animals.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000044
egg size defective early emb
Egg is smaller or larger compared to eggs of control animals.
WB:cab
WB:cgc7141
The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000045
developmental delay postembryonic
The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control.
WB:WBPaper00025054
WB:cab
More than five minutes between AB and P1 divisions.
Emb
pace of P lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000046
pace of P lineage defective early emb
More than five minutes between AB and P1 divisions.
WB:cab
WB:cgc7141
Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space.
gastrulation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000047
gastrulation variant
Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space.
WB:WBPaper00027251
WB:WBPerson2021
Variations in the ability of an animal to emerge from the protective egg shell compared to control animals.
hatching abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000048
hatching variant
Variations in the ability of an animal to emerge from the protective egg shell compared to control animals.
GO:0035188
WB:WBPerson2021
Any variation in the progression of an animal over time, from hatching to adulthood, compared to control.
postembryonic development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000049
postembryonic development variant
Any variation in the progression of an animal over time, from hatching to adulthood, compared to control.
WB:WBPerson2021
Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
Emb
C_elegans_phenotype_ontology
egg lethal
embryonic death
inviable zygote
WBPhenotype:0000050
embryonic lethal
Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WB:WBPaper00000179
WB:WBPaper00004403
WB:WBPaper00004540
WB:WBPaper00004651
WB:WBPaper00004769
WB:WBPaper00005654
WB:WBPaper00024497
WB:WBPaper00024925
WB:WBPaper00025054
WB:cab
The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal.
Emb
Etv
C_elegans_phenotype_ontology
WBPhenotype:0000051
embryonic terminal arrest variable emb
The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal.
GO:0009790
WB:WBPaper00004811
WB:WBPaper00024944
WB:WBPerson712
Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis.
Emb
Mel
C_elegans_phenotype_ontology
WBPhenotype:0000052
maternal effect lethal emb
Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis.
WB:WBPaper00001109
WB:WBPerson2021
Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae.
Pat
C_elegans_phenotype_ontology
active elongation arrest
two fold arrest
WBPhenotype:0000053
paralyzed arrested elongation two fold
Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae.
WB:cab
WB:cgc1894
The animal dies at any time between hatching and onset to adulthood.
Let
Lvl
C_elegans_phenotype_ontology
larval death
WBPhenotype:0000054
larval lethal
The animal dies at any time between hatching and onset to adulthood.
GO:0002119
WB:WBPerson712
Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development.
C_elegans_phenotype_ontology
WBPhenotype:0000055
early larval arrest
Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development.
WB:cab
Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development.
C_elegans_phenotype_ontology
WBPhenotype:0000056
late larval arrest
Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development.
WB:cab
Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle.
Let
Lvl
C_elegans_phenotype_ontology
WBPhenotype:0000057
early larval lethal
Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle.
WB:WBPerson2021
Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle.
Let
Lvl
C_elegans_phenotype_ontology
WBPhenotype:0000058
late larval lethal
Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle.
WB:WBPerson2021
The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
Lva
C_elegans_phenotype_ontology
WBPhenotype:0000059
larval arrest
The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
WB:WBPaper00002958
WB:WBPerson2021
Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background.
Adl
Let
C_elegans_phenotype_ontology
WBPhenotype:0000060
adult lethal
Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background.
WB:WBPaper00004402
WB:WBPaper00005654
WB:WBPaper00006395
WB:cab
Adl
WB:WBPaper00004402
WB:WBPaper00005654
The duration of viability in the adult phase of the life-cycle surpasses that of control animals.
Age
C_elegans_phenotype_ontology
life span increased
longevity increased
WBPhenotype:0000061
extended life span
The duration of viability in the adult phase of the life-cycle surpasses that of control animals.
GO:0008340
WB:WBPerson712
Animals die prematurely at any stage of the life cycle.
Let
C_elegans_phenotype_ontology
WBPhenotype:0000062
lethal
Animals die prematurely at any stage of the life cycle.
WB:WBPaper00001109
WB:WBPerson2021
Variations that cause developmental progression to cease at different stages of the lifecycle.
Var
C_elegans_phenotype_ontology
WBPhenotype:0000063
terminal arrest variable
Variations that cause developmental progression to cease at different stages of the lifecycle.
WB:WBPerson2021
WB:WBPerson557
Animals die prematurely at any stage of the life cycle in a sex dependent manner.
C_elegans_phenotype_ontology
Let
WBPhenotype:0000064
sexually dimorphic lethality
Animals die prematurely at any stage of the life cycle in a sex dependent manner.
WB:WBPerson2021
WB:WBPerson557
XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals.
Let
C_elegans_phenotype_ontology
male specific lethality
WBPhenotype:0000065
X0 lethal
XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals.
WB:WBPerson363
WB:WBPerson712
XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals.
C_elegans_phenotype_ontology
hermaphrodite specific lethality
WBPhenotype:0000066
XX lethal
XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals.
WB:WBPerson363
WB:WBPerson712
Animals exhibit variations in response to stress stimuli compared to control animals.
organism stress response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000067
organism stress response variant
Animals exhibit variations in response to stress stimuli compared to control animals.
GO:0006950
WB:WBPerson712
Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control.
oxidative stress response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000068
cellular oxidative stress response variant
Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control.
GO:0034599
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control.
progeny abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000069
progeny variant
Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan.
Mab
male tail morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000070
male tail morphology variant
Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan.
WB:WBPaper00027278
WB:WBPerson712
Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control.
head morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000071
head morphology variant
Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals.
body morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000072
body morphology variant
Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas).
tail morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000073
tail morphology variant
Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control.
genetic pathway abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000074
genetic pathway variant
Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas).
cuticle attachment abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000075
cuticle attachment variant
Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control.
epithelial attachment abnormal
C_elegans_phenotype_ontology
hypodermal attachment abnormal
WBPhenotype:0000076
epithelial attachment variant
Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement.
cuticle shedding abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000077
cuticle shedding defect
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement.
GO:0018996
The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells .
C_elegans_phenotype_ontology
WBPhenotype:0000078
seam cells stacked
The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells .
WB:WBPaper00003081
The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000079
branched adult alae
The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals lack the anterior portion of the pharynx.
Aph
C_elegans_phenotype_ontology
WBPhenotype:0000080
no anterior pharynx
Animals lack the anterior portion of the pharynx.
WB:WBPerson2021
WB:WBPerson557
The developmental program of the animals does not continue past the first larval stage (L1).
C_elegans_phenotype_ontology
WBPhenotype:0000081
L1 arrest
The developmental program of the animals does not continue past the first larval stage (L1).
WB:WBPaper00003179
WB:WBPerson2021
The developmental program of the animals does not continue past the second larval stage (L2).
C_elegans_phenotype_ontology
WBPhenotype:0000082
L2 arrest
The developmental program of the animals does not continue past the second larval stage (L2).
WB:WBPaper00003179
WB:WBPerson2021
The developmental program of the animals does not continue past the third larval stage (L3).
C_elegans_phenotype_ontology
WBPhenotype:0000083
L3 arrest
The developmental program of the animals does not continue past the third larval stage (L3).
WB:WBPaper00004813
WB:WBPerson2021
The developmental program of the animals does not continue past the fourth larval stage (L4).
C_elegans_phenotype_ontology
WBPhenotype:0000084
L4 arrest
The developmental program of the animals does not continue past the fourth larval stage (L4).
WB:WBPaper00003179
WB:WBPerson2021
The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema).
C_elegans_phenotype_ontology
WBPhenotype:0000085
swollen intestinal lumen
The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema).
WB:WBPaper00026641
WB:WBPerson712
Intestine is shrunken and may appear constricted.
C_elegans_phenotype_ontology
WBPhenotype:0000086
shrunken intestine
Intestine is shrunken and may appear constricted.
WB:WBPaper00005941
Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
body wall cell development abnormal
C_elegans_phenotype_ontology
body wall muscle cell development abnormal
WBPhenotype:0000087
body wall cell development variant
Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas).
C_elegans_phenotype_ontology
body wall muscle displaced
WBPhenotype:0000088
body muscle displaced
The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000089
alpha amanitin resistant
Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal.
C_elegans_phenotype_ontology
hypodermis detached from cuticle
WBPhenotype:0000090
epidermis cuticle detached
Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal.
WB:WBPerson2021
WB:WBPerson557
The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis.
C_elegans_phenotype_ontology
hypodermis detached from muscle
WBPhenotype:0000091
epidermis muscle detached
The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis.
WB:WBPerson2021
WB:WBPerson557
Any variation in the processes that govern the expansion of intestinal cell populations compared to control.
intestinal cell proliferation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000092
intestinal cell proliferation variant
Any variation in the processes that govern the expansion of intestinal cell populations compared to control.
WB:WBPerson2021
The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals.
Lin
lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000093
lineage variant
The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas).
anus development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000094
anus development variant
Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage.
M lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000095
M lineage variant
The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage.
WB:WBPerson2021
Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas).
cloacal development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000096
cloacal development variant
Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals.
AB lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000097
AB lineage variant
The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals.
WB:WBPaper00001584
WB:WBPerson2021
Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas).
pharyngeal intestinal valve development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000098
pharyngeal intestinal valve development variant
Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals.
P lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000099
P lineages variant
The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
cell UV response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000100
cell UV response variant
Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
WB:WBPerson557
Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000101
UV induced apoptosis increased
Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control.
WB:WBPerson712
Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals.
presynaptic vesicle cluster abnormal
C_elegans_phenotype_ontology
synaptic vesicle cluster abnormal
WBPhenotype:0000102
presynaptic vesicle cluster variant
Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals.
WB:WBPaper00027305
Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
gut granule development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000103
gut granule development variant
Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell.
cell polarity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000104
cell polarity variant
Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell.
WB:WBPaper00031356
WB:WBPerson2021
WB:WBPerson712
Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly.
Oma
oocyte meiotic maturation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000105
oocyte meiotic maturation variant
Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly.
GO:0001556
WB:WBPaper00026997
WB:WBPerson2021
Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals.
inhibition of oocyte maturation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000106
inhibition of oocyte maturation variant
Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals.
WB:WBPaper00003371
WB:WBPaper00026997
WB:WBPerson2021
Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
inhibition of ovulation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000107
inhibition of ovulation variant
Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
GO:0060280
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000108
obsolete severe dumpy
true
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000109
obsolete moderate dumpy
true
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000110
obsolete slightly dumpy
true
Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals.
pattern of gene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000111
pattern of gene expression variant
Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals.
WB:WBPerson2021
Variations in the biogenesis and stability of protein molecules compared to control.
protein expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000112
protein expression variant
Variations in the biogenesis and stability of protein molecules compared to control.
WB:WBPerson2021
Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control.
RNA expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000113
RNA expression variant
Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control.
WB:WBPerson2021
Variations in the biogenesis and stability of messenger RNA molecules compared to control.
mRNA expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000114
mRNA expression variant
Variations in the biogenesis and stability of messenger RNA molecules compared to control.
GO:0050684
WB:WBPerson2021
Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb).
anterior pharynx abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000115
anterior pharynx variant
Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb).
WB:WBPerson2021
WB:WBPerson557
Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle.
Let
Lvl
C_elegans_phenotype_ontology
WBPhenotype:0000116
mid larval lethal
Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle.
WB:WBPerson2021
Animals die at the L1 stage of the life cycle.
Let
Lvl
C_elegans_phenotype_ontology
WBPhenotype:0000117
L1 lethal
Animals die at the L1 stage of the life cycle.
WB:WBPerson2021
L2 lethal: Animals die at the L2 stage of the life cycle.
Let
Lvl
C_elegans_phenotype_ontology
WBPhenotype:0000118
L2 lethal
L2 lethal: Animals die at the L2 stage of the life cycle.
WB:WBPerson2021
Any change that results in higher than normal levels of protein expression compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000119
protein expression increased
Any change that results in higher than normal levels of protein expression compared to control animals.
WB:WBPerson557
Any change that results in lower than normal levels of protein expression compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000120
protein expression reduced
Any change that results in lower than normal levels of protein expression compared to control animals.
WB:kmva
Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control.
translation abnormal
C_elegans_phenotype_ontology
protein synthesis abnormal
WBPhenotype:0000121
translation variant
Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control.
GO:0006412
WB:WBPerson2021
Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control.
post translational processing abnormal
C_elegans_phenotype_ontology
protein processing variant
WBPhenotype:0000122
post translational processing variant
Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control.
GO:0016485
WB:WBPerson2021
WB:WBPerson557
Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000123
enzyme expression level reduced
Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals.
WB:WBPerson2021
Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
C_elegans_phenotype_ontology
WBPhenotype:0000124
enzyme activity reduced
Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
WB:WBPerson2021
WB:WBPerson557
Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
C_elegans_phenotype_ontology
WBPhenotype:0000125
enzyme activity increased
Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
WB:WBPerson2021
WB:WBPerson557
Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals.
Emb
general pace of development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000126
general pace of development defective early emb
Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals.
WB:cab
WB:cgc7141
Characteristic exit from the dauer stage is altered compared to control animals.
dauer recovery abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000127
dauer recovery variant
Characteristic exit from the dauer stage is altered compared to control animals.
WB:cab
Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals.
Hid
C_elegans_phenotype_ontology
WBPhenotype:0000128
temperature induced dauer formation increased
Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals.
WB:cgc424
Animals do not enter dauer at a temperature that induces dauer formation in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000129
temperature induced dauer formation defective
Animals do not enter dauer at a temperature that induces dauer formation in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000130
pheromone induced dauer formation enhanced
Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals.
Phd
C_elegans_phenotype_ontology
WBPhenotype:0000131
pheromone induced dauer formation defective
Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals.
pheromone induced dauer formation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000132
pheromone induced dauer formation variant
Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals.
WB:WBPerson2021
WB:WBPerson557
The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000133
expression lipogenic enzyme reduced
The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals.
WB:WBPerson2021
Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000134
gene expression level reduced
Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals.
WB:WBPerson2021
Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000135
gene expression level high
Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals.
WB:WBPerson2021
Animals exhibit elevated levels of messenger RNA compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000136
mRNA levels increased
Animals exhibit elevated levels of messenger RNA compared to control.
WB:WBPaper00033456
WB:WBPerson2021
Animals exhibit decreased levels of messenger RNA compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000137
mRNA levels reduced
Animals exhibit decreased levels of messenger RNA compared to control.
WB:WBPaper00033456
WB:WBPerson2021
The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals.
lipid composition abnormal
C_elegans_phenotype_ontology
fat composition abnormal
fatty acid composition abnormal
WBPhenotype:0000138
lipid composition variant
The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals.
WB:WBPerson712
Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals.
stress induced lethality abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000139
stress induced lethality variant
Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals.
stress induced arrest abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000140
stress induced arrest variant
Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals.
WB:WBPerson2021
WB:WBPerson557
Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000141
stress induced lethality increased
Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
cell stress response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000142
cell stress response variant
Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0033554
WB:WBPerson2021
Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
organism UV response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000143
organism UV response variant
Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
WB:WBPerson557
Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000144
pathogen induced cell death increased
Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
WB:WBPerson712
Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control.
fertility variant
fertility abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000145
fertility phenotype
Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control.
GO:0000003
WB:WBPerson2021
WB:WBPerson557
Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span.
organism temperature response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000146
organism temperature response variant
Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span.
WB:WBPerson712
Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control.
organism starvation response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000147
organism starvation response variant
Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control.
GO:0042594
WB:WBPerson2021
Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals.
starvation induced dauer formation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000148
starvation induced dauer formation variant
Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000149
starvation induced dauer formation increased
Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000150
starvation induced dauer formation defective
Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals.
WB:WBPerson2021
WB:WBPerson557
Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere.
Apx
C_elegans_phenotype_ontology
WBPhenotype:0000151
anterior pharynx extra cells
Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere.
WB:WBPaper00001930
WB:WBPerson2021
One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000152
no cleavage furrow first division early emb
One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
GO:0032154
WB:WBPerson2021
WB:WBPerson557
Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals.
body wall contraction variant
body wall contraction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000153
body wall muscle contraction abnormal
Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals.
WB:WBPaper00032190
WB:WBPerson712
The characteristic number of offspring produced is lower compared to that of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000154
reduced brood size
The characteristic number of offspring produced is lower compared to that of control animals.
WB:WBPerson557
Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped.
C_elegans_phenotype_ontology
WBPhenotype:0000155
cell polarity reversed
Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped.
WB:WBPaper00031356
WB:WBPerson2021
WB:WBPerson712
Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol.
body wall contraction interval abnormal
C_elegans_phenotype_ontology
body wall muscle contraction interval abnormal
WBPhenotype:0000156
body wall muscle contraction interval during defecation abnormal
Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals.
pBoc
posterior body wall contraction abnormal
C_elegans_phenotype_ontology
posterior body contraction abnormal
posterior body wall contraction defective
WBPhenotype:0000157
posterior body wall contraction defecation cycle variant
Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals.
WB:WBPaper00031426
WB:WBPerson712
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000158
obsolete posterior body wall shortened interval
true
OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas).
C_elegans_phenotype_ontology
WBPhenotype:0000159
obsolete dauer arrest variant
true
OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas).
WB:WBPerson2021
WB:WBPerson557
Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000160
cleavage furrow not discrete early emb
Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
GO:0032154
WB:WBPerson2021
WB:WBPerson557
Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control.
nuclear rotation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000161
nuclear rotation variant
Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control.
GO:0035047
WB:WBPerson2021
WB:WBPerson557
Larva show deficiencies in chroma resulting in increased translucency.
C_elegans_phenotype_ontology
translucent
WBPhenotype:0000162
pale larva
Larva show deficiencies in chroma resulting in increased translucency.
WB:WBPerson2021
WB:WBPerson557
Larva appear unusually transparent when compared to control.
Clr
C_elegans_phenotype_ontology
transparent
WBPhenotype:0000163
clear larva
Larva appear unusually transparent when compared to control.
WB:WBPerson557
Animals exhibit a reduced girth compared to a control animal of the same developmental stage.
C_elegans_phenotype_ontology
decreased girth
slim
WBPhenotype:0000164
thin
Animals exhibit a reduced girth compared to a control animal of the same developmental stage.
WB:WBPerson712
Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing.
cell fusion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000165
cell fusion variant
Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing.
GO:0000768
GO:0045026
WB:WBPaper00005122
WB:WBPerson2021
Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation.
seam cell fusion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000166
seam cell fusion variant
Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation.
WB:WBPerson2021
WB:WBPerson557
Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000167
precocious seam cell fusion
Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas).
alae secretion abnormal
C_elegans_phenotype_ontology
alae formation variant
WBPhenotype:0000168
alae secretion variant
Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas).
WB:WBPaper00004833
WB:WBPaper00025242
WB:WBPerson2021
Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells.
C_elegans_phenotype_ontology
WBPhenotype:0000169
early exit cell cycle
Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells.
GO:0010458
WB:WBPerson557
WB:WBPerson712
Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage.
C_elegans_phenotype_ontology
WBPhenotype:0000170
precocious alae
Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage.
WB:cab
pmid:3428573
Any aberrancy in the processes that govern expansion of cell populations compared to control animals.
cell proliferation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000171
cell proliferation variant
Any aberrancy in the processes that govern expansion of cell populations compared to control animals.
GO:0008283
WB:WBPerson2021
The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased.
C_elegans_phenotype_ontology
WBPhenotype:0000172
cell proliferation increased
The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased.
WB:WBPerson2021
The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased.
C_elegans_phenotype_ontology
WBPhenotype:0000173
cell proliferation reduced
The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased.
WB:WBPerson2021
Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas).
basal lamina development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000174
basal lamina development variant
Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body.
C_elegans_phenotype_ontology
WBPhenotype:0000175
hypercontracted
Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body.
WB:WBPerson363
Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated.
satiety behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000176
satiety behavior variant
Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated.
WB:WBPerson2021
WB:WBPerson557
Any variation that results in a decrease of acetylcholine esterase levels, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000177
acetylcholinesterase reduced
Any variation that results in a decrease of acetylcholine esterase levels, compared to control.
WB:WBPaper00024452
WB:WBPerson2021
Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.
C_elegans_phenotype_ontology
WBPhenotype:0000178
cell degeneration
Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.
WB:WBPerson712
Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles.
C_elegans_phenotype_ontology
WBPhenotype:0000179
neuron degeneration
Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles.
WB:WBPerson712
WB:WBperson557
Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals.
axon morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000180
axon morphology variant
Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals.
GO:0030424
WB:WBPaper00005236
WB:WBPerson712
Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals.
axon trajectory abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000181
axon trajectory variant
Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals.
WB:WBPaper00001105
WB:WBPerson712
Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000182
apoptosis reduced
Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
GO:0043065
WB:WBPerson2021
Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000183
apoptosis increased
Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
GO:0043066
WB:WBPerson2021
Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
C_elegans_phenotype_ontology
WBPhenotype:0000184
apoptosis fails to occur
Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
WB:WBPerson712
Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells.
C_elegans_phenotype_ontology
WBPhenotype:0000185
apoptosis protracted
Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells.
WB:WBPerson712
Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals.
WBPhenotype:0000896
oocyte germ cell differentiation abnormal
oogenesis abnormal
C_elegans_phenotype_ontology
oocyte development abnormal
WBPhenotype:0000186
oogenesis variant
Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals.
GO:0048477
WB:WBPerson2021
The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center.
C_elegans_phenotype_ontology
WBPhenotype:0000187
egg round
The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center.
WB:WBPerson2021
WB:WBPerson557
Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad.
gonad arm morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000188
gonad arm morphology variant
Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad.
WB:WBPerson2021
WB:WBPerson557
Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body.
C_elegans_phenotype_ontology
WBPhenotype:0000189
hypodermis disorganized
Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body.
WB:WBPaper00027006
WB:WBPerson2021
Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development.
C_elegans_phenotype_ontology
WBPhenotype:0000190
no dauer recovery
Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development.
GO:0043054
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas).
organism crowding response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000191
organism crowding response variant
Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate.
C_elegans_phenotype_ontology
WBPhenotype:0000192
constitutive enzyme activity
Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate.
WB:WBPerson2021
WB:WBPerson557
Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype.
C_elegans_phenotype_ontology
WBPhenotype:0000193
dominant negative enzyme
Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype.
WB:WBPerson2021
Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals.
first polar body position abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000194
first polar body position variant
Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern.
distal tip cell migration abnormal
C_elegans_phenotype_ontology
DTC migration abnormal
WBPhenotype:0000195
distal tip cell migration variant
Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern.
GO:0040039
WB:WBPaper00003598
WB:WBPerson2021
The morphological appearance of distal tip cells is varied compared to control animals.
distal tip cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000196
distal tip cell morphology variant
The morphological appearance of distal tip cells is varied compared to control animals.
WB:cab
Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling).
cell induction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000197
cell induction variant
Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling).
GO:0031128
WB:WBPerson2021
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000198
obsolete vulval cell induction abnormal
true
Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals.
male tail sensory ray development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000199
male tail sensory ray development variant
Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control.
pericellular component development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000200
pericellular component development variant
Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas).
cuticle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000201
cuticle development variant
Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas).
alae abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000202
alae variant
Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals.
odorant adaptation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000203
odorant adaptation variant
Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals.
WB:WBPerson2021
Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step.
aBoc
C_elegans_phenotype_ontology
anterior body contraction abnormal
anterior body contraction defective
WBPhenotype:0000204
anterior body contraction defecation cycle variant
Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step.
WB:WBPerson2021
Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion.
expulsion abnormal
C_elegans_phenotype_ontology
Exp
WBPhenotype:0000205
expulsion variant
Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion.
WB:WBPerson2021
WB:WBPerson557
A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog.
C_elegans_phenotype_ontology
WBPhenotype:0000206
autosomal nondisjunction meiosis
A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog.
GO:0045143
WB:WBPerson712
Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control .
defecation cycle abnormal
C_elegans_phenotype_ontology
Dec
WBPhenotype:0000207
defecation cycle variant
Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control .
WB:WBPerson2021
WB:WBPerson557
The mean time between the onset of the defecation motor program is greater than that observed for control animals.
C_elegans_phenotype_ontology
Dec-l
reduced rate of defecation
WBPhenotype:0000208
long defecation cycle
The mean time between the onset of the defecation motor program is greater than that observed for control animals.
WB:WBPaper00002315
WB:WBPaper00031896
WB:WBPerson712
The mean time between the onset of the defecation motor program is shorter than that observed for control animals.
posterior body wall shortened interval
C_elegans_phenotype_ontology
Dec-s
fast Dec
increased rate of defecation
WBPhenotype:0000209
short defecation cycle
The mean time between the onset of the defecation motor program is shorter than that observed for control animals.
WB:WBPaper00002315
WB:WBPaper00031896
WB:WBPerson712
Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
defecation contraction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000210
defecation contraction variant
Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
WB:WBPerson2021
WB:WBPerson557
The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control.
C_elegans_phenotype_ontology
defecation contraction mistimed
WBPhenotype:0000211
defecation contraction asynchronous
The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals contain body regions that are more narrow or drawn together than adjacent body regions.
C_elegans_phenotype_ontology
WBPhenotype:0000212
body constriction
Animals contain body regions that are more narrow or drawn together than adjacent body regions.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control.
zygotic development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000213
zygotic development variant
Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000214
alpha amanitin hypersensitive
Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline.
no germline
C_elegans_phenotype_ontology
WBPhenotype:0000215
no germ line
Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline.
WB:WBPaper00001477
WB:WBPerson2021
Any variation in the processes that govern acquisition of particular cell fates compared to control animals.
cell fate specification abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000216
cell fate specification variant
Any variation in the processes that govern acquisition of particular cell fates compared to control animals.
WB:kmva
The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment.
C_elegans_phenotype_ontology
WBPhenotype:0000217
prolonged pharyngeal contraction
The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment.
WB:WBPerson2021
WB:WBPerson557
An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals.
Hin
overinduced
C_elegans_phenotype_ontology
WBPhenotype:0000218
vulval cell induction increased
An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals.
WB:WBPerson2021
Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals.
underinduced
C_elegans_phenotype_ontology
WBPhenotype:0000219
vulval cell induction reduced
Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals.
WB:WBPerson2021
Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals.
vulva cell fate specification abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000220
vulva cell fate specification variant
Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals.
WB:WBPerson2021
Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
neurotransmitter metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000221
neurotransmitter metabolism variant
Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
GO:0042133
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control.
serotonin metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000222
serotonin metabolism variant
Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control.
GO:0042428
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline.
acetylcholine metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000223
acetylcholine metabolism variant
Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline.
GO:0008291
WB:WBPerson557
WB:WBPerson712
Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity.
C_elegans_phenotype_ontology
WBPhenotype:0000224
serotonin deficient
Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity.
WB:WBPerson712
Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin.
C_elegans_phenotype_ontology
WBPhenotype:0000225
serotonin synthesis defective
Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin.
GO:0042427
WB:WBPerson557
WB:WBPerson712
Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter.
C_elegans_phenotype_ontology
WBPhenotype:0000226
serotonin catabolism defective
Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter.
GO:0042429
WB:WBPerson557
WB:WBPerson712
The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail.
male turning abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000227
male turning defective
The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail.
GO:0034607
WB:WBPaper00000392
WB:WBPaper00002109
Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations.
C_elegans_phenotype_ontology
WBPhenotype:0000228
spontaneous mutation rate increased
Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations.
WB:WBPaper00000565
WB:WBPerson712
Animals are shorter and thinner than control animals at the same developmental stage.
body size reduced
C_elegans_phenotype_ontology
Sma
WBPhenotype:0000229
small
Animals are shorter and thinner than control animals at the same developmental stage.
WB:cab
WB:cgc31
The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons.
C_elegans_phenotype_ontology
Wit
WBPhenotype:0000230
tail withered
The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons.
WB:WBPaper00002795
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage.
body size abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000231
PATO:0000117.
body size variant
Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage.
WB:WBPerson712
Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo.
CAN cell migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000232
CAN cell migration variant
Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo.
WB:WBPaper00002795
WB:WBPerson2021
Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control.
dopamine metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000233
dopamine metabolism variant
Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control.
GO:0042417
WB:WBPerson557
WB:WBPerson712
Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals.
C_elegans_phenotype_ontology
dopamine levels decreased
WBPhenotype:0000234
dopamine deficient
Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals.
WB:WBPerson712
Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine.
C_elegans_phenotype_ontology
WBPhenotype:0000235
dopamine synthesis defective
Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine.
GO:0042416
WB:WBPerson557
WB:WBPerson712
Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
C_elegans_phenotype_ontology
WBPhenotype:0000236
dopamine catabolism defective
Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
GO:0042420
WB:WBPerson557
WB:WBPerson712
Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute.
C_elegans_phenotype_ontology
WBPhenotype:0000237
foraging hyperactive
Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute.
WB:WBPaper00031455
WB:WBPaper00031570
WB:WBPerson712
Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000238
foraging reduced
Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals.
WB:WBPaper00031455
WB:WBPerson712
The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p.
vulval cell lineage abnormal
C_elegans_phenotype_ontology
VPC lineage abnormal
WBPhenotype:0000239
vulval cell lineage variant
The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p.
WB:WBPaper00005610
WB:WBPerson2021
The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000240
blast cell proliferation reduced
The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control.
WB:WBPerson2021
Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed.
C_elegans_phenotype_ontology
WBPhenotype:0000241
accumulated cell corpses
Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed.
WB:WBPerson712
The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
C_elegans_phenotype_ontology
WBPhenotype:0000242
body elongation defective
The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
WB:WBPerson2021
Removal of cell corpses through a dedicated engulfment pathway is defective.
C_elegans_phenotype_ontology
corpse engulfment defective
persistent cell corpses
WBPhenotype:0000243
engulfment failure by killer cell
Removal of cell corpses through a dedicated engulfment pathway is defective.
WB:WBPerson712
Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
C_elegans_phenotype_ontology
apoptosis block
WBPhenotype:0000244
apoptotic arrest
Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
WB:WBPerson712
Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad.
SM migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000245
SM migration variant
Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad.
WB:WBPaper00003627
WB:WBPerson2021
Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000246
defecation cycle variable length
Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals.
WB:WBPaper00031896
WB:WBPerson712
Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant.
C_elegans_phenotype_ontology
Na chemotaxis defective
sodium acetate chemotaxis defective
WBPhenotype:0000247
sodium chemotaxis defective
Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant.
WB:cab
WB:cgc387
sodium acetate chemotaxis defective
WB:WBPerson2021
OBSOLETE.
sensory neuroanatomy abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000248
obsolete sensory neuroanatomy variant
true
OBSOLETE.
WB:WBPerson557
Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000249
osmotic avoidance defective
Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals.
WB:WBPerson2021
WB:cab
Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control.
octopamine metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000250
octopamine metabolism variant
Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control.
GO:0046333
WB:WBPerson557
WB:WBPerson712
Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity.
C_elegans_phenotype_ontology
WBPhenotype:0000251
octopamine deficient
Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity.
WB:WBPerson712
Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000252
caffeine resistant
Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another.
C_elegans_phenotype_ontology
movement irregular
WBPhenotype:0000253
movement erratic
Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another.
WB:WBPerson2021
WB:WBPerson557
Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant.
C_elegans_phenotype_ontology
Cl chemotaxis defective
WBPhenotype:0000254
chloride chemotaxis defective
Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant.
WB:cab
WB:cgc387
Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
amphid phasmid morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000255
WBbt:0005394, WBbt:0006753.
amphid phasmid neuron morphology variant
Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000938
Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
amphid morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000256
WBbt:0005394.
amphid neuron morphology variant
Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000938
Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
phasmid morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000257
WBbt:0006753.
phasmid neuron morphology variant
Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000938
Variations in the regulated release of substances by a cell compared to control.
WBPhenotype:0000723
cellular secretion abnormal
cell secretion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000258
cell secretion variant
Variations in the regulated release of substances by a cell compared to control.
GO:0032940
WB:WBPerson2021
Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control.
sheath cell secretion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000259
sheath cell secretion variant
Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control.
WB:WBPaper00000822
WB:WBPerson2021
The regulated release of materials by sheath cells is disrupted.
C_elegans_phenotype_ontology
WBPhenotype:0000260
sheath cell secretion failure
The regulated release of materials by sheath cells is disrupted.
WB:WBPaper00028924
WB:WBPerson2021
Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket.
C_elegans_phenotype_ontology
WBPhenotype:0000261
amphid sheath secretion failure
Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket.
WB:WBPaper00028924
WB:WBPerson2021
Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center.
axoneme morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000262
axoneme morphology variant
Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center.
WB:WBPaper00000932
WB:WBPerson557
WB:WBPerson712
The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000263
axoneme short
The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals.
WB:WBPaper00000932
WB:WBPerson557
WB:WBPerson712
Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant.
C_elegans_phenotype_ontology
WBPhenotype:0000264
cAMP chemotaxis defective
Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant.
WB:WBPaper00001481
WB:WBPaper00002033
WB:cab
WB:cgc387
Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons.
odorant positive chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000265
odorant positive chemotaxis variant
Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons.
WB:WBPerson2021
WB:cab
WB:cgc1786
Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control.
cell cleavage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000266
cell cleavage variant
Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation that causes a delay in the stereotypical cleavage event compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000267
cell cleavage delayed
Any variation that causes a delay in the stereotypical cleavage event compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000268
P cell cleavage delayed
Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification.
C_elegans_phenotype_ontology
WBPhenotype:0000269
obsolete unclassified
true
OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification.
WB:WBPerson2021
WB:WBPerson557
Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000270
pleiotropic defects severe early emb
Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity.
WB:cab
WB:cgc7141
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000271
obsolete cell cycle slow
true
The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000272
egg laying irregular
The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms.
C_elegans_phenotype_ontology
WBPhenotype:0000273
thrashing reduced
The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms.
WB:cab
WB:cgc7388
Animals lay eggs that are inviable.
C_elegans_phenotype_ontology
WBPhenotype:0000274
dead eggs laid
Animals lay eggs that are inviable.
WB:cab
Organisms respond to UV at a lower dose or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000275
organism UV hypersensitive
Organisms respond to UV at a lower dose or a shorter exposure compared to control animals.
WB:WBPerson557
Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals.
organism X ray response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000276
organism X ray response variant
Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals.
WB:WBPerson557
The timing of a biological cycle that recurs with regularity is delayed compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000277
rhythm slow
The timing of a biological cycle that recurs with regularity is delayed compared to control.
GO:0048511
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region.
body region pigmentation abnormal
body region pigmentation variant
C_elegans_phenotype_ontology
WBPhenotype:0000278
body region pigmentation phenotype
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region.
WB:WBPerson557
Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.
C_elegans_phenotype_ontology
WBPhenotype:0000279
spicule insertion defective
Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.
GO:0034609
WB:WBPerson2021
WB:WBPerson557
The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas).
gapped alae
C_elegans_phenotype_ontology
WBPhenotype:0000280
breaks in alae
The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control.
male sex muscle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000281
male sex muscle development variant
Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control.
hermaphrodite sex muscle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000282
hermaphrodite sex muscle development variant
Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals.
AC block
C_elegans_phenotype_ontology
WBPhenotype:0000283
vulva uterus connection defective
Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals.
WB:WBPaper00003386
WB:WBPaper00006298
WB:WBPaper00027236
WB:WBPaper00027316
WB:WBPerson712
Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract.
C_elegans_phenotype_ontology
WBPhenotype:0000284
sperm transfer defective
Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract.
GO:0007320
WB:WBPerson2021
WB:WBPerson557
The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended.
C_elegans_phenotype_ontology
WBPhenotype:0000285
ray tips swollen
The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended.
WB:WBPerson2021
WB:WBPerson557
Embryos fail to be organized in the same manner as observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000286
embryo disorganized
Embryos fail to be organized in the same manner as observed in control animals.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000287
obsolete vulval invagination L4 abnormal
true
Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals.
distal germline abnormal
C_elegans_phenotype_ontology
distal germ line abnormal
WBPhenotype:0000288
distal germline variant
Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas).
uterus morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000289
uterus morphology variant
Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals lack fully specialized male gametes that are competent for fertilization.
C_elegans_phenotype_ontology
no sperm
WBPhenotype:0000290
sperm absent
Animals lack fully specialized male gametes that are competent for fertilization.
WB:WBPerson2021
Hermaphrodites lack fully specialized female gametes that are competent for fertilization.
C_elegans_phenotype_ontology
oocytes absent
WBPhenotype:0000291
no oocytes
Hermaphrodites lack fully specialized female gametes that are competent for fertilization.
WB:WBPerson2021
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system.
organ system pigmentation abnormal
organ system pigmentation variant
C_elegans_phenotype_ontology
WBPhenotype:0000292
organ system pigmentation phenotype
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system.
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system.
alimentary system pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000293
alimentary system pigmentation variant
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system.
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine.
Din
C_elegans_phenotype_ontology
WBPhenotype:0000294
intestine dark
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine.
WB:WBPerson557
Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals.
intrinsic thermotolerance increased
C_elegans_phenotype_ontology
WBPhenotype:0000295
thermotolerance increased
Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals.
WB:WBPaper00005836
WB:WBPerson712
The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules.
C_elegans_phenotype_ontology
WBPhenotype:0000296
spicules crumpled
The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules.
WB:WBPerson2021
WB:WBPerson557
Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another.
WBPhenotype:0001241
ray fusion
C_elegans_phenotype_ontology
WBPhenotype:0000297
rays fused
Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another.
WB:WBPerson2021
WB:WBPerson557
Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place.
C_elegans_phenotype_ontology
WBPhenotype:0000298
rays displaced
Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals.
sensillum morphology abnormal
C_elegans_phenotype_ontology
chemosensory cell morphology abnormal
WBPhenotype:0000299
sensillum morphology variant
Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals.
WB:WBPaper00000214
WB:WBPaper00000938
WB:WBPerson712
Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures.
amphid sheath cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000300
amphid sheath cell morphology variant
Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures.
WB:WBPaper00000214
WB:WBPaper00000503
WB:WBPaper00000822
WB:WBPerson712
A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm.
C_elegans_phenotype_ontology
WBPhenotype:0000301
distal tip cell reflex failure
A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm.
WB:WBPaper00029151
WB:WBPerson2021
Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive.
C_elegans_phenotype_ontology
WBPhenotype:0000302
benzaldehyde chemotaxis defective
Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive.
WB:WBPaper00001786
Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive.
C_elegans_phenotype_ontology
WBPhenotype:0000303
diacetyl chemotaxis defective
Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive.
WB:WBPaper00001786
Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive.
C_elegans_phenotype_ontology
WBPhenotype:0000304
isoamyl alcohol chemotaxis defective
Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive.
WB:cab
WB:cgc1786
Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals.
pheromone sensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000305
pheromone sensation variant
Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals.
GO:0043695
WB:WBPerson2021
WB:WBPerson557
Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals.
transgene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000306
transgene expression variant
Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals.
WB:WBPerson557
Animals fail to detect a pheromone stimulus that induces dauer formation in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000307
dauer pheromone sensation defective
Animals fail to detect a pheromone stimulus that induces dauer formation in control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage.
WBPhenotype:0000159
dauer development abnormal
dauer development variant
C_elegans_phenotype_ontology
dauer arrest abnormal
dauer arrest variant
diapause variant
WBPhenotype:0000308
dauer development phenotype
Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage.
WB:kmva
Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000309
SDS sensitive dauer
Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control.
WB:WBPerson2021
Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000310
cilia absent
Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals.
WB:WBPaper00000932
WB:WBPerson712
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000311
obsolete semi sterile
true
Animals are incapable of synthesizing pheromones that induce dauer formation in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000312
dauer pheromone production defective
Animals are incapable of synthesizing pheromones that induce dauer formation in control animals.
GO:0042446
WB:WBPerson2021
Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis).
meiotic progression during oogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000313
meiotic progression during oogenesis variant
Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis).
WB:WBPaper00026997
WB:WBPerson2021
Animals are slight or meager in body size compared to control animals at the same developmental stage.
C_elegans_phenotype_ontology
WBPhenotype:0000314
scrawny
Animals are slight or meager in body size compared to control animals at the same developmental stage.
WB:WBPerson2021
WB:WBPerson557
Any variation with respect to perception or response to mechanical stimuli compared to control animals.
WBPhenotype:0000513
Mec
touch response abnormal
mechanosensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000315
mechanosensation variant
Any variation with respect to perception or response to mechanical stimuli compared to control animals.
WB:cab
Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail.
touch resistant posterior body
C_elegans_phenotype_ontology
touch insensitive tail
WBPhenotype:0000316
touch resistant tail
Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail.
WB:WBPaper00000502
WB:WBPaper00001133
WB:WBPaper00001705
WB:WBPerson557
Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000317
head withdrawal defective
Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells.
C_elegans_phenotype_ontology
WBPhenotype:0000318
cell cycle delayed
Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells.
WB:WBPerson712
Animals have increased girth and increased length compared to control animals at the same developmental stage.
body size enlarged
C_elegans_phenotype_ontology
WBPhenotype:0000319
large
Animals have increased girth and increased length compared to control animals at the same developmental stage.
WB:WBPerson2021
WB:WBPerson557
Animals show a decrease in survivorship after thawing compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000320
reduced viability after freezing
Animals show a decrease in survivorship after thawing compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control.
nose morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000321
nose morphology variant
Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control.
WB:WBPerson2021
WB:WBPerson557
The extreme anterior part of the body appears blunted in shape.
C_elegans_phenotype_ontology
WBPhenotype:0000322
nose rounded
The extreme anterior part of the body appears blunted in shape.
WB:WBPerson2021
WB:WBPerson557
The most anterior portion of the animal appears bloated or distended.
C_elegans_phenotype_ontology
WBPhenotype:0000323
head swollen
The most anterior portion of the animal appears bloated or distended.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit a decreased body length compared to control animals of the same developmental stage.
C_elegans_phenotype_ontology
WBPhenotype:0000324
short
Animals exhibit a decreased body length compared to control animals of the same developmental stage.
WB:WBPerson712
Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000325
arecoline hypersensitive
Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000326
arecoline resistant
Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000327
corpus contraction defect
Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine.
terminal bulb contraction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000328
terminal bulb contraction variant
Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine.
WB:WBPaper00001696
The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously.
C_elegans_phenotype_ontology
WBPhenotype:0000329
pumping asynchronous
The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously.
WB:WBPaper00001696
Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid.
C_elegans_phenotype_ontology
WBPhenotype:0000330
pharyngeal relaxation defective
Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid.
WB:WBPaper00001709
Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
ouabain resistant
C_elegans_phenotype_ontology
WBPhenotype:0000331
inhibitors of na k atpase resistant
Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson2021
Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000332
inhibitors of sodium potassium ATPase hypersensitive
Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000333
pharyngeal pumps brief
The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx.
C_elegans_phenotype_ontology
WBPhenotype:0000334
isthmus corpus slippery
Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx.
WB:WBPaper00001696
Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen.
C_elegans_phenotype_ontology
WBPhenotype:0000335
pharynx slippery
Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen.
WB:WBPaper00001696
Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position.
terminal bulb relaxation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000336
terminal bulb relaxation variant
Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position.
WB:WBPaper00001696
Failure of the grinder to come to a full relaxed position between pumps compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000337
grinder relaxation defective
Failure of the grinder to come to a full relaxed position between pumps compared to control.
WB:WBPaper00001709
Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum.
Dar
C_elegans_phenotype_ontology
deformed anal region
WBPhenotype:0000338
tail swelling
Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum.
WB:WBPaper00026735
WB:cab
Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus.
C_elegans_phenotype_ontology
WBPhenotype:0000339
transient bloating
Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus.
WB:WBPerson2021
WB:WBPerson557
Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000340
imipramine resistant
Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000341
imipramine hypersensitive
Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control.
bursa morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000342
bursa morphology variant
Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000343
obsolete cloaca morphology abnormal
true
Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening.
C_elegans_phenotype_ontology
WBPhenotype:0000344
cloacal structures protrude
Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening.
WB:WBPerson2021
WB:WBPerson557
Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control.
VPC cell division abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000345
VPC cell division variant
Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control.
WB:WBPerson2021
WB:WBPerson557
Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals.
adult pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000346
adult pigmentation variant
Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals.
WB:WBPerson557
Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system.
rectal development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000347
rectal development variant
Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000348
obsolete muscle activation defective
true
A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas).
C_elegans_phenotype_ontology
floppy
limp
WBPhenotype:0000349
flaccid
A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000350
hermaphrodite tail spike variant
Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals fail to emerge from an egg shell.
C_elegans_phenotype_ontology
WBPhenotype:0000351
failure to hatch
Animals fail to emerge from an egg shell.
GO:0035188
WB:WBPerson2021
Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion.
C_elegans_phenotype_ontology
WBPhenotype:0000352
backing uncoordinated
Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion.
WB:WBPaper00001709
Animals spend more time backing compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000353
backing increased
Animals spend more time backing compared to control animals.
WB:cab
Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues.
cell differentiation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000354
cell differentiation variant
Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues.
WB:WBPerson2021
Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000355
HSN differentiation precocious
Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control.
WB:WBPerson2021
The progression of immature germ cells to functional sperm is retarded compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000356
spermatogenesis delayed
The progression of immature germ cells to functional sperm is retarded compared to control.
WB:WBPaper00005566
WB:WBPerson2021
Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm.
C_elegans_phenotype_ontology
WBPhenotype:0000357
unfertilized oocytes laid
Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm.
WB:WBPaper00001075
WB:WBPerson2021
Animals execute supernumerary cell divisions post-hatching.
C_elegans_phenotype_ontology
supernumerary cell divisions
WBPhenotype:0000358
extra cell division postembryonic
Animals execute supernumerary cell divisions post-hatching.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response.
tunicamycin response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000359
tunicamycin response variant
Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response.
WB:WBPaper00030877
WB:WBperson557
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired.
C_elegans_phenotype_ontology
WBPhenotype:0000360
Possible XP.
cytoplasmic streaming defective
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired.
GO:0099636
WB:WBPaper00050908
WB:WBPerson2021
WB:WBPerson557
Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas).
Emb
C_elegans_phenotype_ontology
arrest during epiboly
WBPhenotype:0000361
lima bean arrest
Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas).
blastocoel abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000362
blastocoel variant
Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000363
cell division slow
Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control.
WB:WBPerson2021
WB:WBPerson557
The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen.
C_elegans_phenotype_ontology
WBPhenotype:0000364
gut granule birefringence misplaced
The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen.
WB:WBPaper00025094
Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing.
Emb
Eos
C_elegans_phenotype_ontology
WBPhenotype:0000365
embryo osmotic integrity defective early emb
Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing.
WB:cab
WB:cgc7141
Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo.
Emb
C_elegans_phenotype_ontology
active elongation arrest
WBPhenotype:0000366
three fold arrest
Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo.
WB:WBPerson101
Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas).
Emb
C_elegans_phenotype_ontology
end of epiboly arrest
WBPhenotype:0000367
comma arrest emb
Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo.
Emb
C_elegans_phenotype_ontology
arrest beginning elongation
WBPhenotype:0000368
one point five fold arrest emb
Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo.
WB:WBPerson101
Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas).
Emb
C_elegans_phenotype_ontology
end of elongation arrest
WBPhenotype:0000369
pretzel arrest
Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The fertilized oocytes have a greater than standard length measured end to end compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000370
egg long
The fertilized oocytes have a greater than standard length measured end to end compared to control.
WB:WBPerson2021
WB:WBPerson557
The physical partitioning and separation of a cell into daughter cells is interupted.
C_elegans_phenotype_ontology
WBPhenotype:0000371
cell division incomplete
The physical partitioning and separation of a cell into daughter cells is interupted.
WB:WBPerson2021
WB:WBPerson557
Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000372
no polar body formation
Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000373
egg shape variable
The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals.
WB:WBPerson2021
WB:WBPerson557
The time interval in which early embryonic cell divisions occur is increased compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000374
early divisions prolonged
The time interval in which early embryonic cell divisions occur is increased compared to control.
WB:WBPerson2021
WB:WBPerson557
The time interval in which late embryonic cell divisions occur is increased compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000375
later divisions prolonged
The time interval in which late embryonic cell divisions occur is increased compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000376
no uterine cavity
Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals.
canal lumen morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000377
canal lumen morphology variant
Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Pharyngeal muscle contractions show less displacement than that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000378
pharyngeal pumping shallow
Pharyngeal muscle contractions show less displacement than that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
The most anterior portion of the animal contains a V-shaped indentation.
C_elegans_phenotype_ontology
WBPhenotype:0000379
head notched
The most anterior portion of the animal contains a V-shaped indentation.
WB:WBPaper00000031
The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus.
C_elegans_phenotype_ontology
WBPhenotype:0000380
expulsion infrequent
The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus.
WB:WBPaper00002315
WB:WBPerson712
Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000381
serotonin reuptake inhibitor resistant
Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000382
serotonin reuptake inhibitor hypersensitive
Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
The de novo synthesis of any lipid species is reduced compared to that observed in control animals.
C_elegans_phenotype_ontology
lipid synthesis decreased
WBPhenotype:0000383
lipid synthesis defective
The de novo synthesis of any lipid species is reduced compared to that observed in control animals.
WB:WBPerson712
Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues).
axon guidance abnormal
C_elegans_phenotype_ontology
axon pathfinding abnormal
WBPhenotype:0000384
axon guidance variant
Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues).
GO:0048846
WB:WBPerson2021
Animals produce an increased sperm population compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000385
sperm excess
Animals produce an increased sperm population compared to control.
WB:WBPerson2021
Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals.
genotoxic induced apoptosis abnormal
C_elegans_phenotype_ontology
DNA damage induced apoptosis abnormal
WBPhenotype:0000386
genotoxic chemical induced apoptosis variant
Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals.
WB:WBPaper00032006
WB:WBPaper00032243
WB:WBPaper00032356
WB:WBPerson712
The mature male gametes lack self-propelled movement.
C_elegans_phenotype_ontology
WBPhenotype:0000387
sperm nonmotile
The mature male gametes lack self-propelled movement.
GO:0030317
WB:WBPerson2021
WB:WBPerson557
Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas).
sperm morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000388
sperm morphology variant
Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte.
Fer
Spe
C_elegans_phenotype_ontology
WBPhenotype:0000389
hermaphrodite sperm fertilization defective
Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte.
WB:WBPaper00001075
WB:WBPerson2021
Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases.
C_elegans_phenotype_ontology
spermiogenesis defective
WBPhenotype:0000390
spermatid activation defective
Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases.
WB:WBPaper00000884
WB:WBPaper00027300
WB:WBPerson2021
Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
C_elegans_phenotype_ontology
WBPhenotype:0000391
defecation missing motor steps
Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine.
C_elegans_phenotype_ontology
WBPhenotype:0000392
intestinal fluorescence increased
Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine.
WB:WBPerson557
Characteristic movement of cells from one site to another is abolished compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000393
cell migration failure
Characteristic movement of cells from one site to another is abolished compared to control.
WB:WBPerson2021
Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000394
electrophoretic variant protein
Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals are agametic (lack mature germ cells).
C_elegans_phenotype_ontology
WBPhenotype:0000395
no differentiated gametes
Animals are agametic (lack mature germ cells).
WB:WBPerson2021
Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern.
C_elegans_phenotype_ontology
WBPhenotype:0000396
non reflexed gonad arms
Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern.
WB:WBPaper00005086
WB:WBPaper00029151
WB:WBPerson2021
Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls.
C_elegans_phenotype_ontology
harsh body touch insensitive
WBPhenotype:0000397
harsh body touch resistant
Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls.
WB:WBPaper00000502
Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls.
C_elegans_phenotype_ontology
light body touch insensitive
WBPhenotype:0000398
light body touch resistant
Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls.
WB:WBPaper00000502
Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas).
somatic gonad development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000399
somatic gonad development variant
Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000400
somatic gonad primordium development defective
The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000401
no uterus
Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal.
C_elegans_phenotype_ontology
WBPhenotype:0000402
avoids bacterial lawn
Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal.
WB:WBPaper00029071
WB:WBPerson2021
Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000403
sperm transfer initiation defective
Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control.
WB:WBPaper00028400
The emergence of larvae from their protective egg shells is retarded compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000404
delayed hatching
The emergence of larvae from their protective egg shells is retarded compared to control animals.
GO:0035188
WB:WBPerson2021
The size of haploid female germ cells (oocytes) are significantly larger compared to control.
C_elegans_phenotype_ontology
oocytes large
WBPhenotype:0000405
giant oocytes
The size of haploid female germ cells (oocytes) are significantly larger compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals have protrusions or bumps on their exterior which are not characteristic of control animals.
Lpy
C_elegans_phenotype_ontology
WBPhenotype:0000406
lumpy
Animals have protrusions or bumps on their exterior which are not characteristic of control animals.
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000407
obsolete ray loss
true
The process through which a dauer larva reverts to normal developmental programs is blocked.
C_elegans_phenotype_ontology
WBPhenotype:0000408
dauer recovery inhibited
The process through which a dauer larva reverts to normal developmental programs is blocked.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals.
Vab
C_elegans_phenotype_ontology
WBPhenotype:0000409
organism morphology variable
Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000410
no defecation cycle
Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell.
Lvl
C_elegans_phenotype_ontology
Let
WBPhenotype:0000411
rod like larval lethal
Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell.
WB:WBPaper00001366
WB:WBPaper00002764
WB:WBPerson2021
Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant.
C_elegans_phenotype_ontology
WBPhenotype:0000412
octanol chemotaxis defective
Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant.
WB:WBPaper00002314
Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation.
C_elegans_phenotype_ontology
WBPhenotype:0000413
pharyngeal muscle paralyzed
Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation.
WB:WBPerson557
WB:cab
The cell takes on a different identity from which it was initially committed.
C_elegans_phenotype_ontology
WBPhenotype:0000414
cell fate transformation
The cell takes on a different identity from which it was initially committed.
GO:0045165
WB:WBPaper00002924
WB:WBPerson712
Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control.
necrotic cell death abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000415
necrotic cell death variant
Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control.
GO:0070265
WB:WBPerson712
Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas).
yolk synthesis abnormal
C_elegans_phenotype_ontology
vitellogenin synthesis abnormal
WBPhenotype:0000416
yolk synthesis variant
Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The process of physical partitioning and separation of a cell into daughter cells is abolished.
C_elegans_phenotype_ontology
WBPhenotype:0000417
cell division failure
The process of physical partitioning and separation of a cell into daughter cells is abolished.
WB:WBPerson2021
WB:WBPerson557
The physical partitioning and separation of an intestinal cell into daughter cells is abolished.
C_elegans_phenotype_ontology
WBPhenotype:0000418
intestinal cell division failure
The physical partitioning and separation of an intestinal cell into daughter cells is abolished.
WB:WBPerson2021
WB:WBPerson557
Animals die at the L3 stage of the life cycle.
Let
Lvl
C_elegans_phenotype_ontology
WBPhenotype:0000419
L3 lethal
Animals die at the L3 stage of the life cycle.
WB:WBPerson2021
Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist.
C_elegans_phenotype_ontology
tetramisole hypersensitive
WBPhenotype:0000420
levamisole hypersensitive
Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist.
WB:WBPerson557
Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc.
Lev R
C_elegans_phenotype_ontology
tetramisole resistant
WBPhenotype:0000421
levamisole resistant
Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc.
WB:WBPaper00000484
WB:WBPerson2021
Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion.
C_elegans_phenotype_ontology
WBPhenotype:0000422
twitcher
Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion.
WB:WBPaper00000484
Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control.
head muscle contraction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000423
head muscle contraction variant
Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control.
WB:WBPerson557
Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
antibody staining abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000424
antibody staining variant
Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000425
antibody staining reduced
Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000426
antibody staining increased
Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000427
no cuticle
Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000428
no adult cuticle
Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control.
copulatory structure development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000429
copulatory structure development variant
Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas).
male copulatory structure development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000430
male copulatory structure development variant
Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control.
hermaphrodite copulatory structure development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000431
hermaphrodite copulatory structure development variant
Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000432
male copulatory structure absent
Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the processes involving the production of new DNA strands compared to control.
DNA synthesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000433
DNA synthesis variant
Variations in the processes involving the production of new DNA strands compared to control.
GO:0006260
WB:WBPerson2021
The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired.
C_elegans_phenotype_ontology
WBPhenotype:0000434
sexual maturation defective
The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired.
GO:0003006
WB:WBPerson2021
WB:WBPerson557
OBSOLETE. Any change in the subcellular localization of a protein.
C_elegans_phenotype_ontology
WBPhenotype:0000435
obsolete protein localization abnormal
true
Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
WBPhenotype:0000435
protein localization abnormal
protein subcellular localization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000436
protein subcellular localization variant
Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000437
obsolete heterochronic defect
true
Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000438
retarded heterochronic variations
Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
GO:0040034
WB:WBPerson2021
WB:WBPerson557
Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000439
precocious heterochronic variations
Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control.
GO:0040034
WB:WBPerson2021
WB:WBPerson557
The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
C_elegans_phenotype_ontology
long excretory canals
WBPhenotype:0000440
excretory canals long
The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail.
C_elegans_phenotype_ontology
WBPhenotype:0000441
tail rounded
Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail.
WB:WBPerson2021
WB:WBPerson557
The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood.
C_elegans_phenotype_ontology
WBPhenotype:0000442
larval development retarded
The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood.
WB:WBPerson2021
WB:WBPerson557
Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control.
spicule morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000443
spicule morphology variant
Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control.
WB:WBPerson2021
WB:WBPerson557
The length of the adult male tail, including the lateral fan and rays, is extended compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000444
bursa elongated
The length of the adult male tail, including the lateral fan and rays, is extended compared to control.
WB:WBPerson2021
WB:WBPerson557
Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells.
C_elegans_phenotype_ontology
vitellogenin synthesis in males
WBPhenotype:0000445
yolk synthesis in males
Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells.
WB:WBPerson2021
WB:WBPerson557
Animals execute extra larval molts compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000446
supernumerary molt
Animals execute extra larval molts compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals.
adult development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000447
adult development variant
Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas).
adult cuticle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000448
adult cuticle development variant
Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells.
C_elegans_phenotype_ontology
WBPhenotype:0000449
second adult cuticle
A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells.
WB:WBPaper00001439
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000450
obsolete swollen male tail
true
Any irregular swelling in discrete regions of the head.
C_elegans_phenotype_ontology
WBPhenotype:0000451
head protrusion
Any irregular swelling in discrete regions of the head.
WB:WBPerson2021
WB:WBPerson557
Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000452
tail protrusions
Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any irregular swelling in discrete regions of the body region between the head and the tail.
C_elegans_phenotype_ontology
WBPhenotype:0000453
body protrusions
Any irregular swelling in discrete regions of the body region between the head and the tail.
WB:WBPerson2021
WB:WBPerson557
The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding.
C_elegans_phenotype_ontology
WBPhenotype:0000454
head twisted
The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit abrupt transitions while traveling from one location to another.
C_elegans_phenotype_ontology
WBPhenotype:0000455
jerky movement
Animals exhibit abrupt transitions while traveling from one location to another.
WB:WBPerson2021
WB:WBPerson557
Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals.
C_elegans_phenotype_ontology
touch insensitive
WBPhenotype:0000456
touch resistant
Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals.
WB:WBPerson557
Animals show enhanced suceptibility to deprivation of nourishment, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000457
organism starvation hypersensitive
Animals show enhanced suceptibility to deprivation of nourishment, compared to control.
WB:WBPerson2021
Animals show enhanced tolerance to deprivation of nourishment, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000458
starvation resistant
Animals show enhanced tolerance to deprivation of nourishment, compared to control.
WB:WBPerson2021
Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals.
pesticide response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000459
pesticide response variant
Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals.
WB:WBPerson557
Animals exhibit variations in their response to paraquat compared to that observed in control animals.
paraquat response abnormal
C_elegans_phenotype_ontology
methyl viologen response abnormal
WBPhenotype:0000460
paraquat response variant
Animals exhibit variations in their response to paraquat compared to that observed in control animals.
WB:WBPerson557
Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000461
paraquat resistant
Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals.
reactive oxygen species hypersensitive
C_elegans_phenotype_ontology
WBPhenotype:0000462
paraquat hypersensitive
Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
reactive oxygen species hypersensitive
WB:WBPaper00031296
Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
metabolic pathway abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000463
metabolic pathway variant
Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0008152
WB:WBPerson712
Animals exhibit variations in their response to oxygen compared to that observed in control animals.
oxygen response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000464
oxygen response variant
Animals exhibit variations in their response to oxygen compared to that observed in control animals.
WB:WBPerson557
Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000465
high oxygen resistant
Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals.
WB:WBPerson2021
Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000466
high oxygen hypersensitive
Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control.
GO:0055093
WB:WBPerson2021
Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000467
age associated fluorescence increased
Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
WB:WBPaper00033040
WB:WBPerson2021
Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000468
age associated fluorescence reduced
Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control.
WB:WBPerson2021
The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals.
Q neuroblast lineage migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000469
Q neuroblast lineage migration variant
The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals.
WB:WBPaper00001954
WB:WBPaper00031356
WB:WBPerson712
Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals.
HSN migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000470
HSN migration variant
Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals.
WB:WBPaper00001836
WB:WBPerson2021
Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals.
ALM migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000471
ALM migration variant
Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals.
WB:WBPaper00001304
WB:WBPaper00003058
WB:WBPerson2021
Animals lack the early blast cells that give rise to the gut tissue (Wormatlas).
gutless
C_elegans_phenotype_ontology
WBPhenotype:0000472
endoderm absent
Animals lack the early blast cells that give rise to the gut tissue (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals become increasingly sluggish/immobilized as they age.
C_elegans_phenotype_ontology
WBPhenotype:0000473
progressive paralysis
Animals become increasingly sluggish/immobilized as they age.
WB:WBPaper00001709
Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control.
Mua
muscle attachment abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000474
muscle attachment variant
Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues.
C_elegans_phenotype_ontology
WBPhenotype:0000475
muscle detached
Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues.
WB:WBPerson2021
WB:WBPerson557
The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time.
C_elegans_phenotype_ontology
WBPhenotype:0000476
progressive muscle detachment
The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time.
WB:WBPerson2021
WB:WBPerson557
Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus.
nucleolus refraction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000477
nucleolus refraction variant
Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus.
WB:WBPerson2021
WB:WBPerson557
Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature.
isothermal tracking behavior abnormal
C_elegans_phenotype_ontology
thermotaxis abnormal
WBPhenotype:0000478
isothermal tracking behavior variant
Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature.
WB:WBPaper00002214
Eggs show deficiencies in chroma resulting in increased translucency.
C_elegans_phenotype_ontology
WBPhenotype:0000479
egg pale
Eggs show deficiencies in chroma resulting in increased translucency.
WB:WBPerson2021
WB:WBPerson557
Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant.
C_elegans_phenotype_ontology
WBPhenotype:0000480
pyrazine chemotaxis defective
Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant.
WB:WBPaper00001786
Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals.
negative chemotaxis abnormal
C_elegans_phenotype_ontology
chemical avoidance abnormal
chemoaversion abnormal
WBPhenotype:0000481
negative chemotaxis variant
Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals.
GO:0050919
WB:cab
Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent.
C_elegans_phenotype_ontology
WBPhenotype:0000482
garlic chemotaxis defective
Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent.
WB:WBPaper00001374
Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000483
no gut granules
Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The organism's size during the embryonic developmental stage is decreased compared to that observed in control.
C_elegans_phenotype_ontology
WBPhenotype:0000484
embryo small
The organism's size during the embryonic developmental stage is decreased compared to that observed in control.
WB:WBPerson2021
WB:WBPerson557
The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced.
C_elegans_phenotype_ontology
reduced dauer survival
WBPhenotype:0000485
dauer death increased
The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced.
WB:WBPerson2021
WB:WBPerson557
Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000486
colchicine hypersensitive
Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000487
colchicine resistant
Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000488
chloroquine hypersensitive
Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000489
chloroquine resistant
Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
The components of the feeding organ fail to be arranged in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000490
pharynx disorganized
The components of the feeding organ fail to be arranged in the same manner as control animals.
WB:WBPerson2021
WB:WBPerson557
Any observed morphological defects of the isthmus.
isthmus morphology abnormal
C_elegans_phenotype_ontology
isthmus malformed
WBPhenotype:0000491
isthmus morphology defective
Any observed morphological defects of the isthmus.
WB:WBPerson2021
Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas).
corpus morphology abnormal
C_elegans_phenotype_ontology
corpus malformed
WBPhenotype:0000492
corpus morphology defective
Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas).
WB:WBPerson2021
Any variation in the form, structure or composition of the first pharyngeal bulb compared to control.
metacorpus morphology abnormal
C_elegans_phenotype_ontology
metacarpas malformed
WBPhenotype:0000493
metacorpus morphology defective
Any variation in the form, structure or composition of the first pharyngeal bulb compared to control.
WB:WBPerson2021
Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo.
C_elegans_phenotype_ontology
WBPhenotype:0000494
two fold arrest
Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo.
WB:WBPerson101
Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000495
ray ectopic
Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals.
WB:WBPerson2021
WB:WBPerson557
Males lack the specialized sensory papillae that lie along the posterior half of the body.
C_elegans_phenotype_ontology
WBPhenotype:0000496
male postdeirid sensilla absent
Males lack the specialized sensory papillae that lie along the posterior half of the body.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
organism gamma ray response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000497
organism gamma ray response variant
Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
WB:WBPerson557
Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals.
methyl methanesulfonate response abnormal
C_elegans_phenotype_ontology
MMS response abnormal
WBPhenotype:0000498
methyl methanesulfonate response variant
Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals.
WB:WBPerson557
Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals.
ethyl methanesulfonate response abnormal
C_elegans_phenotype_ontology
EMS response abnormal
WBPhenotype:0000499
ethyl methanesulfonate response variant
Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals.
WB:WBPerson557
Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000500
acetylcholinesterase inhibitor hypersensitive
Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar.
C_elegans_phenotype_ontology
Rol
WBPhenotype:0000501
left handed roller
The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar.
WB:WBPerson2021
WB:WBPerson557
The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar.
Rol
C_elegans_phenotype_ontology
WBPhenotype:0000502
right handed roller
The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar.
WB:WBPerson2021
WB:WBPerson557
Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas).
endoreduplication abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000503
endoreduplication variant
Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control.
nuclear division abnormal
C_elegans_phenotype_ontology
karyokinesis abnormal
WBPhenotype:0000504
Possible XP.
nuclear division variant
Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye.
Ram
male ray morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000505
male ray morphology variant
Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye.
WB:WBPaper00000932
WB:WBPaper00001328
WB:WBPaper00002149
WB:WBPaper00029016
WB:WBPerson712
The adult male tail, including the lateral fan and rays, appears bloated or distended.
swollen male tail
C_elegans_phenotype_ontology
WBPhenotype:0000506
bursa swollen
The adult male tail, including the lateral fan and rays, appears bloated or distended.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline.
acetylcholine levels abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000507
acetylcholine levels variant
Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail.
C_elegans_phenotype_ontology
WBPhenotype:0000508
nonsense mRNA accumulation
Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail.
GO:0070478
WB:WBPerson2021
WB:WBPerson557
Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa.
sperm pseudopod abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000509
sperm pseudopod variant
Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa.
WB:WBPaper00001075
WB:WBPerson2021
The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered.
WBPhenotype:0000287
vulval invagination L4 abnormal
vulval invagination abnormal
C_elegans_phenotype_ontology
vulval invagination L4 variant
WBPhenotype:0000510
vulval invagination variant L4
The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered.
WB:WBPaper00001738
WB:WBPerson2021
Variations in the directed movement of the nucleus to a specific location within a cell compared to control.
nuclear positioning abnormal
C_elegans_phenotype_ontology
nuclear migration variant
WBPhenotype:0000511
Possible XP.
nuclear positioning variant
Variations in the directed movement of the nucleus to a specific location within a cell compared to control.
GO:0007097
WB:WBPerson2021
WB:WBPerson557
Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position.
VNC nuclear positioning abnormal
C_elegans_phenotype_ontology
VNC nuclear migration variant
WBPhenotype:0000512
VNC nuclear positioning variant
Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position.
WB:WBPaper00031891
WB:WBPerson712
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000513
obsolete touch response abnormal
true
When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding.
Rbr
rubberband
C_elegans_phenotype_ontology
WBPhenotype:0000514
rubber band
When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding.
WB:WBPaper00006135
WB:WBPerson2021
Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord.
ventral nerve cord development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000515
ventral nerve cord development variant
Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord.
WB:WBPerson557
The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000516
ventral cord disorganized
The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals.
behavior abnormal
behavior variant
C_elegans_phenotype_ontology
WBPhenotype:0000517
behavior phenotype
Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals.
GO:0007610
WB:WBPerson557
Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals.
development abnormal
development variant
C_elegans_phenotype_ontology
WBPhenotype:0000518
development phenotype
Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals.
GO:0032502
WB:WBPerson2021
Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals.
physiology abnormal
physiology variant
C_elegans_phenotype_ontology
WBPhenotype:0000519
physiology phenotype
Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals.
WB:WBPerson712
Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals.
morphology abnormal
morphology variant
C_elegans_phenotype_ontology
WBPhenotype:0000520
morphology phenotype
Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals.
WB:WBPerson712
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency.
pigmentation abnormal
pigmentation variant
C_elegans_phenotype_ontology
WBPhenotype:0000521
pigmentation phenotype
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency.
WB:WBPerson2021
WB:WBPerson557
WB:WBPerson712
Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals.
organism region behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000522
organism region behavior variant
Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their response to a specific chemical compared to that observed in control animals.
chemical response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000523
chemical response variant
Animals exhibit variations in their response to a specific chemical compared to that observed in control animals.
WB:WBPerson557
Animals exhibit variations in their response to bleach compared to that observed in control animals.
bleach response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000524
bleach response variant
Animals exhibit variations in their response to bleach compared to that observed in control animals.
WB:WBPerson557
Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms.
organism behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000525
organism behavior variant
Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms.
GO:0007610
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell.
cell pigmentation abnormal
cell pigmentation variant
C_elegans_phenotype_ontology
WBPhenotype:0000526
cell pigmentation phenotype
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell.
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism.
organism pigmentation abnormal
organism pigmentation variant
C_elegans_phenotype_ontology
Abnormal Coloration
WBPhenotype:0000527
organism pigmentation phenotype
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism.
WB:WBPerson557
Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
body region development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000528
body region development variant
Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals.
cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000529
cell development variant
Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals.
GO:0048468
WB:cab
Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals.
organ system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000530
organ system development variant
Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals.
GO:0048731
WB:cab
Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control.
organism development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000531
organism development variant
Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control.
WB:cab
Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals.
body region morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000532
body region morphology variant
Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000533
cell morphology variant
Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0005623
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system.
organ system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000534
organ system morphology variant
Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system.
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals.
Bmd
organism morphology abnormal
C_elegans_phenotype_ontology
body morphology defects
WBPhenotype:0000535
organism morphology variant
Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals.
WB:WBPaper00004402
WB:WBPaper00004403
WB:WBPaper00004651
WB:WBPaper00005654
WB:WBPaper00006395
WB:cab
Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals.
cell physiology abnormal
cell physiology variant
C_elegans_phenotype_ontology
WBPhenotype:0000536
cell physiology phenotype
Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals.
GO:0009987
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000537
obsolete synaptic input abnormal
true
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000538
obsolete synaptic output abnormal
true
Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas).
dorsal nerve cord development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000539
dorsal nerve cord development variant
Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas).
muscle arm development abnormal
C_elegans_phenotype_ontology
muscle arm extension variant
WBPhenotype:0000540
muscle arm development variant
Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
WB:WBPerson712
Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords.
C_elegans_phenotype_ontology
WBPhenotype:0000541
cord commissures fail to reach target
Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords.
WB:WBPaper00001499
WB:WBPaper00028984
WB:WBPerson712
Animals exhibit an increased girth compared to a control animal of the same developmental stage.
C_elegans_phenotype_ontology
increased girth
thick
WBPhenotype:0000542
fat
Animals exhibit an increased girth compared to a control animal of the same developmental stage.
WB:WBPerson2021
WB:WBPerson557
Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000543
forward kinker
Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000544
backward kinker
Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Eggs are retained in the uterus at a later stage when compared with control animals.
Ret
C_elegans_phenotype_ontology
late eggs laid
WBPhenotype:0000545
egg retention
Eggs are retained in the uterus at a later stage when compared with control animals.
WB:cab
Eggs are laid at an earlier stage of development when compared with control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000546
early eggs laid
Eggs are laid at an earlier stage of development when compared with control animals.
WB:cab
Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals.
C_elegans_phenotype_ontology
Eat
WBPhenotype:0000547
starved
Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals.
WB:WBPaper00001709
WB:WBPerson2021
Progressive degeneration of muscle.
C_elegans_phenotype_ontology
WBPhenotype:0000548
muscle dystrophy
Progressive degeneration of muscle.
WB:cab
Progressive degeneration of the head muscle.
C_elegans_phenotype_ontology
WBPhenotype:0000549
head muscle dystrophy
Progressive degeneration of the head muscle.
WB:cab
Progressive degeneration of muscle along the body wall.
C_elegans_phenotype_ontology
body wall muscle dystrophy
WBPhenotype:0000550
body muscle dystrophy
Progressive degeneration of muscle along the body wall.
WB:cab
Animals exhibit variations in the rate of sharp head to tail turns compared to control animals.
omega turns abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000551
omega turns variant
Animals exhibit variations in the rate of sharp head to tail turns compared to control animals.
WB:WBPaper00000075
WB:WBPaper00006375
WB:WBPerson712
Animals exhibit variations in the amount of GABA compared to control animals at a defined stage.
GABA levels abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000552
GABA levels variant
Animals exhibit variations in the amount of GABA compared to control animals at a defined stage.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics.
WBPhenotype:0000714
Dim
disorganized muscle
C_elegans_phenotype_ontology
muscle birefringence abnormal
WBPhenotype:0000553
Disorganized muscle fibers display a weak and abnormal birefringency pattern when examined using polarized optics.
muscle birefringence variant
Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics.
WB:WBPerson557
Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode.
C_elegans_phenotype_ontology
WBPhenotype:0000554
hypoosmotic shock hypersensitive
Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode.
WB:WBPaper00000484
WB:WBPerson2021
Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control.
drug adaptation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000555
drug adaptation variant
Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control.
WB:WBPerson2021
WB:WBPerson557
Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control.
dopamine adaptation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000556
dopamine adaptation variant
Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control.
WB:WBPerson2021
WB:WBPerson557
Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine.
C_elegans_phenotype_ontology
WBPhenotype:0000557
dopamine adaptation defective
Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals.
calcium channel modulator response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000558
calcium channel modulator response variant
Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals.
WB:WBPerson557
Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000559
calcium channel modulator hypersensitive
Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000560
calcium channel modulator resistant
Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals.
C_elegans_phenotype_ontology
head tetramisole resistant
WBPhenotype:0000561
head levamisole resistant
The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals.
WB:WBPaper00000484
The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals.
C_elegans_phenotype_ontology
body tetramisole resistant
WBPhenotype:0000562
body levamisole resistant
The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals.
WB:WBPaper00000484
The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000563
shrinker
The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000564
echo defecation cycle
Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals.
WB:WBPaper00002305
WB:WBPaper00003765
WB:WBPerson712
The body of an animal assumes a coil-like shape when it attempts to move.
C_elegans_phenotype_ontology
curler
WBPhenotype:0000565
coiler
The body of an animal assumes a coil-like shape when it attempts to move.
WB:WBPerson363
A coiling body that bends ventrally.
C_elegans_phenotype_ontology
ventral curler
WBPhenotype:0000566
ventral coiler
A coiling body that bends ventrally.
WB:WBPerson363
A coiling body that bends dorsally.
C_elegans_phenotype_ontology
dorsal curler
WBPhenotype:0000567
dorsal coiler
A coiling body that bends dorsally.
WB:WBperson363
Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals.
axon ultrastructure abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000568
axon ultrastructure variant
Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals.
WB:WBPaper00001499
WB:WBPerson712
Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000569
axon varicosities
Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals.
WB:WBPaper00001499
WB:WBPaper00024595
WB:WBPerson712
Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent.
C_elegans_phenotype_ontology
WBPhenotype:0000570
axon cisternae
Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent.
WB:WBPaper00001499
WB:WBPaper00024595
WB:WBPerson712
Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals.
abnormal axon vesicle
C_elegans_phenotype_ontology
WBPhenotype:0000571
axon vesicle variant
Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals.
WB:WBPaper00001499
WB:WBPerson712
Any variation in the processes that govern the extension of neuronal projections.
neuronal outgrowth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000572
neuronal outgrowth variant
Any variation in the processes that govern the extension of neuronal projections.
WB:WBPerson2021
OBSOLETE.
neuronal branching abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000573
obsolete neuronal branching variant
true
OBSOLETE.
WB:WBPerson557
The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000574
excretory canal short
The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control.
organ system physiology abnormal
organ system physiology variant
C_elegans_phenotype_ontology
WBPhenotype:0000575
organ system physiology phenotype
Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control.
GO:0003008
Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli.
organism physiology abnormal
organism physiology variant
C_elegans_phenotype_ontology
WBPhenotype:0000576
organism physiology phenotype
Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli.
WB:WBPerson712
Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control.
organism homeostasis metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000577
organism homeostasis metabolism variant
Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control.
GO:0048871
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals.
body axis development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000578
body axis development variant
Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
organism segment development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000579
organism segment development variant
Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals.
organism segment behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000580
organism segment behavior variant
Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals.
body axis morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000581
body axis morphology variant
Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals.
organism segment morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000582
organism segment morphology variant
Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Worms are shorter and stouter than control animals at the same developmental stage.
Dpy
C_elegans_phenotype_ontology
WBPhenotype:0000583
dumpy
Worms are shorter and stouter than control animals at the same developmental stage.
WB:WBPaper00004402
WB:WBPaper00004403
WB:WBPaper00004651
WB:WBPaper00005654
WB:WBPaper00006395
WB:WBPaper00024497
WB:cab
WB:cgc31
Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals.
WBPhenotype:0000537
WBPhenotype:0000538
synaptic input variant
synaptic output variant
synaptic input abnormal
synaptic output abnormal
synaptic transmission abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000584
synaptic transmission variant
Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals.
GO:0007268
WB:cab
Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control.
cell homeostasis metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000585
cell homeostasis metabolism variant
Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control.
GO:0019725
WB:WBPerson2021
Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000586
bleach hypersensitive
Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
OBSOLETE.
lectin staining abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000587
obsolete lectin staining variant
true
OBSOLETE.
WB:WBPerson557
OBSOLETE.
no male abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000588
This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype.
obsolete no male variantity scored
true
OBSOLETE.
WB:WBPerson557
OBSOLETE.
no hermaphrodite abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000589
This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype.
obsolete no hermaphrodite variantity scored
true
OBSOLETE.
WB:WBPerson557
Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage.
cell corpse number abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000590
cell corpse number variant
Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage.
WB:WBPerson712
Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
metal response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000591
metal response variant
Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
WB:WBPerson557
Animals exhibit variations in their response to copper compared to that observed in control animals.
copper response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000592
copper response variant
Animals exhibit variations in their response to copper compared to that observed in control animals.
WB:WBPerson557
Animals respond to copper at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000593
copper hypersensitive
Animals respond to copper at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Any variation in the orderly movement of a cell from one site to another.
Mig
cell migration abnormal
C_elegans_phenotype_ontology
migration of cells abnormal
WBPhenotype:0000594
cell migration variant
Any variation in the orderly movement of a cell from one site to another.
GO:0016477
WB:cab
Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals.
head behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000595
head behavior variant
Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
WB:cab
Activity characteristic of the body is altered compared to control.
body behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000596
body behavior variant
Activity characteristic of the body is altered compared to control.
WB:cab
Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals.
tail behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000597
tail behavior variant
Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas).
alimentary system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000598
alimentary system morphology variant
Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ.
coelomic system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000599
coelomic system morphology variant
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ.
WB:WBPerson2021
WB:WBPerson557
Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control.
epithelial system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000600
epithelial system morphology variant
Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas).
WBPhenotype:0000602
excretory system morphology variant
excretory secretory system morphology abnormal
excretory system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000601
excretory secretory system morphology variant
Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000602
obsolete excretory system morphology abnormal
true
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work.
muscle system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000603
muscle system morphology variant
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work.
GO:0007517
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals.
nervous system morphology abnormal
C_elegans_phenotype_ontology
neuroanatomical defective
WBPhenotype:0000604
WB:WBbt:0005735.
nervous system morphology variant
Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals.
WB:WBPerson712
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
reproductive system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000605
reproductive system morphology variant
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
alimentary system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000606
alimentary system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
coelomic system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000607
coelomic system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
epithelial system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000608
epithelial system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
excretory secretory system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000609
excretory secretory system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
excretory system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000610
excretory system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
muscle system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000611
muscle system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
nervous system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000612
nervous system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
reproductive system physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000613
reproductive system physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0003008
WB:WBPerson557
WB:WBPerson712
Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
GLR development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000614
GLR development variant
Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside.
cilia morphology abnormal
C_elegans_phenotype_ontology
defective dye filling of cilia
WBPhenotype:0000615
cilia morphology variant
Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside.
WB:WBPaper00000214
WB:WBPaper00000932
WB:WBPerson712
Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft.
synapse morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000616
synapse morphology variant
Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft.
GO:0045202
WB:WBPaper00027305
WB:WBPerson712
Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products.
alimentary system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000617
alimentary system development variant
Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products.
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control.
coelomic system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000618
coelomic system development variant
Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control.
WB:WBPerson2021
Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control.
epithelial system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000619
epithelial system development variant
Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control.
WB:WBPerson2021
Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands.
excretory secretory system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000620
excretory secretory system development variant
Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands.
WB:WBPerson2021
Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell.
excretory system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000621
excretory system development variant
Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell.
WB:WBPerson2021
Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control.
muscle system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000622
muscle system development variant
Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control.
WB:WBPerson2021
Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control.
nervous system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000623
nervous system development variant
Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control.
GO:0007399
WB:cab
Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control.
reproductive system development abnormal
C_elegans_phenotype_ontology
reproductive defect
WBPhenotype:0000624
reproductive system development variant
Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control.
WB:WBPerson2021
Any variation in the biosynthesis of a synapse compared to control.
synapse development variant
synaptogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000625
synaptogenesis variant
Any variation in the biosynthesis of a synapse compared to control.
GO:0007416
WB:cab
synapse development variant
WB:WBPerson712
Any variation in the decrease in a behavioral response to a repeated stimulus compared to control.
habituation abnormal
C_elegans_phenotype_ontology
non associative learning variant
WBPhenotype:0000626
habituation variant
Any variation in the decrease in a behavioral response to a repeated stimulus compared to control.
GO:0046959
WB:cab
Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals.
anaesthetic response variant
anesthetic response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000627
anesthetic response variant
Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals.
WB:WBPerson557
Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000628
Possible XP.
spindle assembly defective early emb
Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GO:0051225
WB:WBPerson2021
WB:cab
WB:cgc7141
Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated.
C_elegans_phenotype_ontology
WBPhenotype:0000629
excess neurite outgrowth
Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated.
WB:WBPerson2021
Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent.
C_elegans_phenotype_ontology
WBPhenotype:0000630
quinine chemotaxis defective
Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent.
WB:WBPaper00006481
WB:WBPaper00035961
WB:WBPerson712
Any variation in the characteristic response(s) to drug(s) as defined by control animals.
C_elegans_phenotype_ontology
drug response abnormal
WBPhenotype:0000631
drug response variant
Any variation in the characteristic response(s) to drug(s) as defined by control animals.
WB:cab
The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised.
axon fasciculation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000632
axon fasciculation variant
The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised.
GO:0007413
WB:WBPerson2021
WB:WBPerson557
Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals.
axon branching abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000633
axon branching variant
Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals.
GO:0048755
WB:WBPaper00027335
WB:WBPaper00027711
WB:WBPerson712
Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control.
pharyngeal pumping abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000634
pharyngeal pumping variant
Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control.
GO:0043050
WB:cab
Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals.
positive chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000635
positive chemotaxis variant
Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals.
GO:0050918
WB:cab
WB:cgc122
WB:cgc387
Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.
neuron degeneration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000636
neuron degeneration variant
Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.
WB:WBPerson2021
WB:WBPerson557
Characteristic entry into the dauer stage is altered compared to control animals.
Daf
dauer formation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000637
dauer formation variant
Characteristic entry into the dauer stage is altered compared to control animals.
WB:cab
Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.
Mlt
Mult
C_elegans_phenotype_ontology
WBPhenotype:0000638
molt defect
Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.
GO:0018996
WB:WBPerson712
Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C.
temperature induced dauer formation abnormal
C_elegans_phenotype_ontology
Hid
WBPhenotype:0000639
temperature induced dauer formation variant
Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C.
WB:WBPaper00006103
WB:WBPerson2021
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control.
Egl
egg laying abnormal
C_elegans_phenotype_ontology
oviposition abnormal
WBPhenotype:0000640
Visual inspection.
egg laying variant
Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control.
WB:cab
pmid:11813735
pmid:9697864
oviposition abnormal
GO:0018991
Any variation in the degree of movement compared to control animals.
activity level abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000641
activity level variant
Any variation in the degree of movement compared to control animals.
WB:cab
Worms move forward or backward with an increased rate of body bends per minute compared to control animals.
Hya
C_elegans_phenotype_ontology
WBPhenotype:0000642
hyperactive
Worms move forward or backward with an increased rate of body bends per minute compared to control animals.
WB:WBPaper00004402
WB:WBPaper00006395
WB:cab
Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals.
Unc
locomotion abnormal
C_elegans_phenotype_ontology
movement defect
uncoordinated
WBPhenotype:0000643
locomotion variant
Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals.
GO:0040011
WB:WBPaper00024949
WB:WBPerson712
WB:cab
Animals do not move and are not responsive to external mechanical stimulation.
Prl
C_elegans_phenotype_ontology
Prz
WBPhenotype:0000644
paralyzed
Animals do not move and are not responsive to external mechanical stimulation.
WB:cab
The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar.
Rol
C_elegans_phenotype_ontology
WBPhenotype:0000645
roller
The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar.
WB:cab
WB:cgc31
Animals move more slowly compared with control animals.
Slu
C_elegans_phenotype_ontology
lethargic
slow
WBPhenotype:0000646
sluggish
Animals move more slowly compared with control animals.
WB:cab
Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another.
copulation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000647
copulation variant
Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another.
GO:0007620
WB:cab
Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control.
Cod
male mating abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000648
male mating variant
Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control.
GO:0060179
WB:cab
Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.
vulva location abnormal
C_elegans_phenotype_ontology
Lov
WBPhenotype:0000649
vulva location variant
Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.
GO:0034608
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas).
defecation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000650
defecation variant
Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas).
GO:0030421
WB:WBPerson2021
WB:WBPerson557
WB:cab
Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter.
Con
C_elegans_phenotype_ontology
WBPhenotype:0000651
constipated
Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter.
WB:WBPerson2021
Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
WBPhenotype:0000248
sensory system abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000652
sensory system variant
Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
mechanosensory system abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000653
mechanosensory system variant
Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control.
synaptic vesicle exocytosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000654
synaptic vesicle exocytosis variant
Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control.
GO:0016079
WB:WBPerson712
Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
GABA synaptic transmission abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000655
GABA synaptic transmission variant
Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
GO:0007268
WB:WBPerson712
Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
acetylcholine synaptic transmission abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000656
acetylcholine synaptic transmission variant
Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control.
GO:0007268
WB:WBPerson712
Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas).
neuronal synaptic transmission abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000657
neuronal synaptic transmission variant
Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals.
neuromuscular synaptic transmission abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000658
neuromuscular synaptic transmission variant
Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Behavior associated with the intake of food is altered compared to control.
feeding behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000659
feeding behavior variant
Behavior associated with the intake of food is altered compared to control.
GO:0007631
WB:WBPerson557
Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects.
C_elegans_phenotype_ontology
bordering increased
social behavior enhanced
WBPhenotype:0000660
social feeding increased
Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects.
WB:WBPerson712
Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent.
C_elegans_phenotype_ontology
solitary behavior enhanced
solitary forager on food
WBPhenotype:0000661
solitary feeding increased
Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent.
WB:WBPaper00003187
WB:WBPaper00032342
WB:WBPerson712
Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region.
Fab
foraging behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000662
foraging behavior variant
Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region.
GO:0060756
WB:WBPaper00005621
WB:WBPaper00031455
WB:WBPerson712
Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength.
osmotic avoidance abnormal
C_elegans_phenotype_ontology
Osm
WBPhenotype:0000663
osmotic avoidance variant
Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength.
WB:WBPerson2021
The maximum ventral and dorsal flex of the animal is greater than that observed for control animals.
WBPhenotype:0004021
C_elegans_phenotype_ontology
loopy
WBPhenotype:0000664
exaggerated body bends
The maximum ventral and dorsal flex of the animal is greater than that observed for control animals.
WB:WBPerson712
Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males.
connection of gonad abnormal
C_elegans_phenotype_ontology
Cog
WBPhenotype:0000665
connection of gonad variant
Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males.
WB:WBPerson2021
WB:WBPerson557
Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
ovulation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000666
ovulation variant
Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control.
GO:0030728
WB:WBPaper00003017
WB:WBPerson2021
The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control.
C_elegans_phenotype_ontology
ectopic gonad
WBPhenotype:0000667
gonad displaced
The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control.
WB:WBPerson2021
WB:WBPerson557
Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized.
Emo
C_elegans_phenotype_ontology
arrest in meiosis I
WBPhenotype:0000668
endomitotic oocytes
Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized.
WB:kmva
Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control.
sex muscle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000669
sex muscle development variant
Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control.
Spe
spermatocyte germ cell differentiation abnormal
spermatogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000670
spermatogenesis variant
Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control.
GO:0007283
WB:WBPaper00027300
WB:WBPerson2021
Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000671
resistant to copper
Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals.
WB:WBPerson557
Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals.
presynaptic vesicle cluster localization abnormal
C_elegans_phenotype_ontology
synaptic vesicle cluster localization abnormal
WBPhenotype:0000672
presynaptic vesicle cluster localization variant
Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals.
WB:WBPaper00027305
WB:WBPaper00027711
WB:WBPerson712
The number of offspring produced is altered compared to that of control animals.
brood size abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000673
brood size variant
The number of offspring produced is altered compared to that of control animals.
WB:WBPerson557
The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control.
C_elegans_phenotype_ontology
retarded development
WBPhenotype:0000674
slow development
The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals die after fusion of gametes without dividing.
C_elegans_phenotype_ontology
Emb
WBPhenotype:0000675
zygotic lethal
Animals die after fusion of gametes without dividing.
WB:WBPerson2021
WB:WBPerson557
The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals.
growth rate abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000676
growth rate variant
The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals.
GO:0040007
WB:WBPerson712
Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000677
chemosensation defective
Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals.
WB:WBPerson2021
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000678
This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype.
obsolete no copper sensitivity
true
OBSOLETE.
WB:WBPerson557
Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
transgene subcellular localization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000679
transgene subcellular localization variant
Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WB:WBPerson557
Animals exhibit variations in their response to aldicarb compared to that observed in control animals.
aldicarb response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000680
aldicarb response variant
Animals exhibit variations in their response to aldicarb compared to that observed in control animals.
WB:WBPerson557
Animals exhibit variations in their response to DMPP compared to that observed in control animals.
DMPP response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000681
DMPP response variant
Animals exhibit variations in their response to DMPP compared to that observed in control animals.
WB:WBPerson557
Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm.
Fog
feminization of germ line
C_elegans_phenotype_ontology
WBPhenotype:0000682
feminization of germline
Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm.
WB:cab
pmid:3396865
The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm.
Mog
masculinization of germ line
C_elegans_phenotype_ontology
WBPhenotype:0000683
masculinization of germline
The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm.
WB:WBPaper00001710
WB:WBPerson2021
Germ cell populations are reduced compared to control animals.
Fgc
C_elegans_phenotype_ontology
germline underproliferation
WBPhenotype:0000684
fewer germ cells
Germ cell populations are reduced compared to control animals.
WB:WBPerson2021
WB:cab
Any variation that causes a reduction in growth rate during larval stages compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000685
larval growth slow
Any variation that causes a reduction in growth rate during larval stages compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their response ionizing radiation compared to that observed in control animals.
organism ionizing radiation response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000686
organism ionizing radiation response variant
Animals exhibit variations in their response ionizing radiation compared to that observed in control animals.
WB:WBPerson557
Both hermaphrodites and males develop into fertile females.
Fem
C_elegans_phenotype_ontology
WBPhenotype:0000687
feminization of XX and XO animals
Both hermaphrodites and males develop into fertile females.
WB:cab
Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
Ste
semi sterile
C_elegans_phenotype_ontology
WBPhenotype:0000688
sterile
Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce.
GO:0000003
WB:WBPerson712
Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).
Ste
Reduced fecundity of injected worm
C_elegans_phenotype_ontology
sterile F0 fertility problems
WBPhenotype:0000689
maternal sterile
Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility).
WB:WBPerson557
WB:cab
WB:cgc5599
WB:cgc7141
Reduced fecundity of injected worm
WB:cgc5599
Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas).
Gom
gonad migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000690
gonad migration variant
Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control.
gonad development abnormal
C_elegans_phenotype_ontology
Gon
gonadogenesis abnormal
WBPhenotype:0000691
gonad development variant
Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control.
GO:0008406
WB:WBPerson2021
X0 animals fail to generate viable cross-progeny.
C_elegans_phenotype_ontology
WBPhenotype:0000692
male sterile
X0 animals fail to generate viable cross-progeny.
WB:WBPerson2021
Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte.
Fer
C_elegans_phenotype_ontology
WBPhenotype:0000693
male sperm fertilization defect
Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte.
WB:WBPaper00001075
WB:WBPerson2021
Hermaphrodites fail to generate viable self-progeny and/or cross-progeny.
C_elegans_phenotype_ontology
WBPhenotype:0000694
hermaphrodite sterile
Hermaphrodites fail to generate viable self-progeny and/or cross-progeny.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control.
vulva morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000695
vulva morphology variant
Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control.
WB:WBPerson712
The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva).
Evl
C_elegans_phenotype_ontology
WBPhenotype:0000696
everted vulva
The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva).
WB:WBPaper00001738
WB:WBPerson2021
WB:WBPerson261
WB:cab
Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva.
Pvl
Pvu
C_elegans_phenotype_ontology
WBPhenotype:0000697
protruding vulva
Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva.
WB:WBPaper00004408
WB:WBPerson2021
No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate.
Vul
underinduced
C_elegans_phenotype_ontology
WBPhenotype:0000698
vulvaless
No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate.
WB:WBPaper00001182
WB:WBPerson2021
Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
vulva development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000699
vulva development variant
Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
GO:0040025
WB:IA
WB:WBPerson2021
Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates.
Muv
overinduced
C_elegans_phenotype_ontology
WBPhenotype:0000700
multivulva
Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates.
WB:WBPaper00001182
WB:WBPerson2021
Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation.
epithelial development abnormal
C_elegans_phenotype_ontology
epidermal morphogenesis variant
WBPhenotype:0000701
epithelial development variant
Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation.
WB:WBPerson2021
WB:WBPerson557
Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development.
PMID:15341747
C_elegans_phenotype_ontology
WBPhenotype:0000702
epithelial cell fusion failure
Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development.
WB:WBPaper00005122
WB:WBPerson2021
Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas).
epithelial morphology abnormal
C_elegans_phenotype_ontology
hypodermal morphology abnormal
WBPhenotype:0000703
epithelial morphology variant
Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas).
excretory canal morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000704
excretory canal morphology variant
Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
intestinal cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000705
intestinal cell development variant
Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages.
Glo
PMID:15843430
C_elegans_phenotype_ontology
gut granule loss
WBPhenotype:0000706
gut granule biogenesis reduced
Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages.
WB:WBPaper00032168
WB:WBPerson712
Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb).
pharyngeal development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000707
pharyngeal development variant
Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb).
GO:0043282
WB:WBPerson2021
Variations in the progression of the intestine over time from its initial formation to its mature structure compared to control.
intestinal development abnormal
C_elegans_phenotype_ontology
endoderm development abnormal
gut development abnormal
WBPhenotype:0000708
intestinal development variant
Variations in the progression of the intestine over time from its initial formation to its mature structure compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the form or composition of the mouthparts at the anterior end of the digestive tract which contain a series of radial muscles, related neurons and epithelial cells, and several gland cells which may aid in digestion compared to control (Wormatlas).
pharyngeal morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000709
pharyngeal morphology variant
Variations in the form or composition of the mouthparts at the anterior end of the digestive tract which contain a series of radial muscles, related neurons and epithelial cells, and several gland cells which may aid in digestion compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas).
intestinal morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000710
intestinal morphology variant
Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit increased sensitivity to the effects of ion producing radiation compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000711
organism hypersensitive ionizing radiation
Animals exhibit increased sensitivity to the effects of ion producing radiation compared to control animals.
WB:WBPaper00000565
WB:WBPerson712
Germ cells exhibit variations in their response to ionizing radiation compared to that observed in control animals.
germ cell ionizing radiation response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000712
germ cell ionizing radiation response variant
Germ cells exhibit variations in their response to ionizing radiation compared to that observed in control animals.
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000713
obsolete spermatocyte division abnormal
true
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000714
obsolete disorganized muscle
true
Animals exhibit a greater number of embryonic muscle cells compared to control.
Mex
C_elegans_phenotype_ontology
WBPhenotype:0000715
muscle excess
Animals exhibit a greater number of embryonic muscle cells compared to control.
WB:WBPaper00001584
WB:kmva
Mex
WB:WBPaper00001584
Any variation in the connection of a cell whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control.
muscle cell attachment abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000716
muscle cell attachment variant
Any variation in the connection of a cell whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control.
gene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000717
gene expression variant
Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control.
GO:0010467
WB:WBPerson2021
Variations in the process of normalizing the expression level of X-linked genes between XX and XO animals compared to control.
dosage compensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000718
Possible XP GO:0007549.
dosage compensation variant
Variations in the process of normalizing the expression level of X-linked genes between XX and XO animals compared to control.
GO:0007549
WB:WBPerson363
OBSOLETE.
reporter gene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000719
obsolete reporter gene expression variant
true
OBSOLETE.
WB:WBPerson557
OBSOLETE.
pattern of reporter gene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000720
obsolete pattern of reporter gene expression variant
true
OBSOLETE.
WB:WBPerson557
OBSOLETE.
level of reporter gene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000721
obsolete level of reporter gene expression variant
true
OBSOLETE.
WB:WBPerson557
Animals exhibit variations in the appearance of nucleoli compared to control animals.
nucleolus abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000722
nucleolus variant
Animals exhibit variations in the appearance of nucleoli compared to control animals.
WB:cab
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000723
obsolete cellular secretion abnormal
true
Variations in the regulated release of proteins from a cell or group of cells compared to control.
protein secretion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000724
protein secretion variant
Variations in the regulated release of proteins from a cell or group of cells compared to control.
GO:0009306
WB:WBPerson2021
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of lipid within the organism or cell compared to control.
lipid metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000725
lipid metabolism variant
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of lipid within the organism or cell compared to control.
GO:0055088
WB:WBPaper00032000
WB:WBPaper00032082
WB:WBPerson712
Any variation of the specific binding of a molecule to its partner, which typically results in a change in cell activity, compared to control.
ligand binding abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000726
ligand binding variant
Any variation of the specific binding of a molecule to its partner, which typically results in a change in cell activity, compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
enzyme activity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000727
enzyme activity variant
Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
GO:0003824
WB:WBPerson2021
WB:WBPerson557
Variations in the process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, compared to control.
exocytosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000728
exocytosis variant
Variations in the process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, compared to control.
GO:0006887
WB:WBPerson2021
Animals exhibit variations in any of the processes that lead to the termination of vital functions of a cell.
Ced
cell death abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000729
cell death variant
Animals exhibit variations in any of the processes that lead to the termination of vital functions of a cell.
GO:0008219
WB:cab
Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.
Ced
apoptosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000730
apoptosis variant
Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.
GO:0006915
WB:WBPerson2021
Germ cells exhibit increased sensitivity to the effects of ion producing radiation compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000731
germ cell hypersensitive ionizing radiation
Germ cells exhibit increased sensitivity to the effects of ion producing radiation compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control.
DNA metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000732
DNA metabolism variant
Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control.
WB:WBPerson2021
Any variation in the catalysis of a biochemical reaction compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
catalysis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000733
catalysis variant
Any variation in the catalysis of a biochemical reaction compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).
GO:0003824
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the hypodermal system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
hypodermal cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000734
hypodermal cell physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the hypodermal system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Any variation in the regulated re-replication of DNA in the hypodermal cells during a single cell cycle, compared to control.
endoreduplication of hypodermal nuclei abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000735
endoreduplication of hypodermal nuclei variant
Any variation in the regulated re-replication of DNA in the hypodermal cells during a single cell cycle, compared to control.
GO:0042023
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control.
autophagy abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000736
autophagy variant
Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control.
GO:0006914
WB:WBPerson712
Germ cells fail to respond to the dosage of ion producing radiation that elicits a response in control animals. Alternatively, germ cells require a higher dosage or a longer exposure to ion producing radiation to elicit the same response as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000737
germ cell resistant ionizing radiation
Germ cells fail to respond to the dosage of ion producing radiation that elicits a response in control animals. Alternatively, germ cells require a higher dosage or a longer exposure to ion producing radiation to elicit the same response as control animals.
WB:WBPerson2021
WB:WBPerson557
The response to a change in the environment is altered compared to control.
organism environmental stimulus response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000738
organism environmental stimulus response variant
The response to a change in the environment is altered compared to control.
WB:cab
Variations in the activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism, compared to control.
DNA damage response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000739
DNA damage response variant
Variations in the activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism, compared to control.
GO:0006974
WB:WBPerson2021
Cells of the animals exhibit variations in the initiation, progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals.
cell cycle abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000740
cell cycle variant
Cells of the animals exhibit variations in the initiation, progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals.
GO:0007049
WB:WBPerson557
WB:WBPerson712
Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage.
DNA damage checkpoint abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000741
DNA damage checkpoint variant
Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage.
WB:WBPaper00029085
WB:WBPerson2021
Variations in the process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents, compared to control.
DNA recombination abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000742
DNA recombination variant
Variations in the process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents, compared to control.
GO:0006310
WB:WBPerson2021
Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control.
Rde
RNAi response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000743
RNAi response variant
Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control.
GO:0016246
WB:WBPerson2021
Animals exhibit variations in the silencing of endogenous genes after introduction of repetitive exogenous cognate DNA compared to control.
transgene induced cosuppression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000744
transgene induced cosuppression variant
Animals exhibit variations in the silencing of endogenous genes after introduction of repetitive exogenous cognate DNA compared to control.
WB:WBPaper00025139
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the activity of endogenous transposons compared to control. In C. elegans transposon activity is often measured by the rate of reversion of mutations induced by transposon insertions.
transposon silencing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000745
transposon silencing variant
Animals exhibit variations in the activity of endogenous transposons compared to control. In C. elegans transposon activity is often measured by the rate of reversion of mutations induced by transposon insertions.
GO:0000335
WB:WBPaper00031962
WB:WBPerson712
Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control.
cell division abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000746
cell division variant
Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control.
GO:0051301
WB:WBPerson2021
Any defects in the muscle contractions that control feeding. Contractions are necessary for bacterial uptake from the surrounding environment.
C_elegans_phenotype_ontology
WBPhenotype:0000747
pharyngeal contraction defective
Any defects in the muscle contractions that control feeding. Contractions are necessary for bacterial uptake from the surrounding environment.
WB:WBPaper00001696
Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes).
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000748
asymmetric cell division defective early emb
Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes).
WB:cab
WB:cgc7141
Variations in the progression of an embryo over time, from zygote formation to hatching compared to control.
embryonic development abnormal
C_elegans_phenotype_ontology
developmental defects detected in embryos
WBPhenotype:0000749
embryonic development variant
Variations in the progression of an embryo over time, from zygote formation to hatching compared to control.
GO:0009790
WB:WBPerson2021
Variations in the progression of a larva over time, from its formation to the mature structure compared to control. The larva is the early, immature form of an animal between hatching and adulthood.
larval development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000750
larval development variant
Variations in the progression of a larva over time, from its formation to the mature structure compared to control. The larva is the early, immature form of an animal between hatching and adulthood.
GO:0002164
WB:WBPerson2021
Variations in the progression of a newly hatched animal through the first larval molt compared to control.
L1 larval development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000751
L1 larval development variant
Variations in the progression of a newly hatched animal through the first larval molt compared to control.
WB:WBPerson2021
Variations in the progression of the second larval stage compared to control.
L2 larval development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000752
L2 larval development variant
Variations in the progression of the second larval stage compared to control.
WB:WBPerson557
Variations in the progression of the third larval stage compared to control.
L3 larval development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000753
L3 larval development variant
Variations in the progression of the third larval stage compared to control.
WB:WBPerson557
Variations in the progression of the fourth larval stage compared to control.
L4 larval development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000754
L4 larval development variant
Variations in the progression of the fourth larval stage compared to control.
WB:WBPerson557
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L1 to L2 transition.
L1 L2 molt abnormal
C_elegans_phenotype_ontology
L1 molt
WBPhenotype:0000755
L1 L2 molt defect
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L1 to L2 transition.
GO:0018996
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L2 to L3 transition.
L2 L3 molt abnormal
C_elegans_phenotype_ontology
L2 molt
WBPhenotype:0000756
L2 L3 molt defect
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L2 to L3 transition.
GO:0018996
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L3 to L4 transition.
L3 L4 molt abnormal
C_elegans_phenotype_ontology
L3 molt
WBPhenotype:0000757
L3 L4 molt defect
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L3 to L4 transition.
GO:0018996
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L4 to adult transition.
L4 adult molt abnormal
C_elegans_phenotype_ontology
L4 molt
WBPhenotype:0000758
L4 adult molt defect
Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L4 to adult transition.
GO:0018996
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle.
Emb
Spd
C_elegans_phenotype_ontology
WBPhenotype:0000759
Possible XP.
spindle defective early emb
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle.
GO:0007051
WB:WBPerson2021
The alignment of the spindle relative to other cellular structures in the cells of an embryo varies from that observed in control animals.
Emb
Spn
C_elegans_phenotype_ontology
WBPhenotype:0000760
spindle orientation defective early emb
The alignment of the spindle relative to other cellular structures in the cells of an embryo varies from that observed in control animals.
WB:WBPerson557
Early embryos exhibit defects in the placement or the alignment of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
Emb
Spo
C_elegans_phenotype_ontology
Spi
WBPhenotype:0000761
spindle position orientation defective early emb
Early embryos exhibit defects in the placement or the alignment of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
WB:WBPerson2021
WB:WBPerson557
Early embryos exhibit defects in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
Abs
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000762
Possible XP.
spindle position defective early emb
Early embryos exhibit defects in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
GO:0051653
WB:WBPerson2021
WB:WBPerson557
Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for an embryonic cell to carry out its normal function and activities or be able to perceive and respond to stimuli.
embryonic cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000763
embryonic cell physiology variant
Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for an embryonic cell to carry out its normal function and activities or be able to perceive and respond to stimuli.
GO:0009987
WB:WBPerson557
Variations in the processes that are carried out at in the embryo which results in its formation or the arrangement of constituent parts, compared to control.
embryonic cell organization biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000764
embryonic cell organization biogenesis variant
Variations in the processes that are carried out at in the embryo which results in its formation or the arrangement of constituent parts, compared to control.
WB:WBPerson2021
WB:WBPerson557
The embryos exhibit defects in the cell cycle process whereby the distance is lengthened between poles of the spindle.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000765
Possible XP.
spindle elongation integrity defective early emb
The embryos exhibit defects in the cell cycle process whereby the distance is lengthened between poles of the spindle.
GO:0051231
WB:WBPerson2021
WB:cab
WB:cgc7141
Any variation in the rotation of the centrosome-pronuclear complex after its migration toward the center of the embryo, compared to control.
Rot
centrosome pair and associated pronuclear rotation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000766
Possible XP.
centrosome pair and associated pronuclear rotation variant
Any variation in the rotation of the centrosome-pronuclear complex after its migration toward the center of the embryo, compared to control.
WB:WBPaper00004895
WB:WBPerson2021
WB:WBPerson557
Sparse or enlarged yolk granules.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000767
integrity of membranous organelles defective early emb
Sparse or enlarged yolk granules.
WB:WBPaper00025054
WB:cab
Areas devoid of yolk granules throughout the embryo.
Emb
cytoplasmic structure abnormal
C_elegans_phenotype_ontology
Aberrant Cytoplasmic Structure
cellular structure disorganized
WBPhenotype:0000768
cytoplasmic structure defective early emb
Areas devoid of yolk granules throughout the embryo.
WB:cab
WB:cgc7141
Embryos exhibit defects in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control embryos.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000769
cytoplasmic appearance defective early emb
Embryos exhibit defects in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control embryos.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the appearance of embryonic cells compared to control.
embryonic cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000770
embryonic cell morphology variant
Animals exhibit variations in the appearance of embryonic cells compared to control.
WB:cab
Centrosomes detach from the male pronucleus.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000771
centrosome attachment defective early emb
Centrosomes detach from the male pronucleus.
WB:cab
WB:cgc7141
Daughter nuclei are deformed and stay close to central cortex, cytokinesis defects.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0000772
sister chromatid segregation defective early emb
Daughter nuclei are deformed and stay close to central cortex, cytokinesis defects.
WB:cab
WB:cgc7141
Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control.
chromosome segregation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000773
chromosome segregation variant
Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control.
GO:0007059
WB:WBPerson2021
WB:WBPerson557
WB:kmva
Any variation in the processes that govern the generation and maintenance of gametes compared to control.
gametogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000774
gametogenesis variant
Any variation in the processes that govern the generation and maintenance of gametes compared to control.
GO:0007276
WB:WBPerson2021
Variations in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells compared to control. Meiosis occurs during the formation of gametes.
meiosis abnormal
C_elegans_phenotype_ontology
Mei
germ cell meiosis abnormal
germ cell meiosis variant
WBPhenotype:0000775
meiosis variant
Variations in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells compared to control. Meiosis occurs during the formation of gametes.
GO:0051321
WB:WBPerson2021
Male and female PNs not visible; embryo often fills egg shell completely.
Emb
passage through meiosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000776
passage through meiosis defective early emb
Male and female PNs not visible; embryo often fills egg shell completely.
WB:cab
WB:cgc71441
Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1.
Emb
polar body extrusion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000777
polar body extrusion defective early emb
Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1.
WB:cab
WB:cgc7141
Animals are unable to ingest nutrients at a rate similar to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000778
feeding inefficient
Animals are unable to ingest nutrients at a rate similar to control animals.
WB:WBPaper00032342
WB:WBPerson712
Cessation of development during the final stages of embryogenesis. In C. elegans, this stage normally occurs 620-800 min after the first cleavage at 20C and is the stage after elongation.
C_elegans_phenotype_ontology
WBPhenotype:0000779
late embryonic arrest
Cessation of development during the final stages of embryogenesis. In C. elegans, this stage normally occurs 620-800 min after the first cleavage at 20C and is the stage after elongation.
WB:WBPerson101
Animals rotate back and forth around their longitudinal axes.
C_elegans_phenotype_ontology
WBPhenotype:0000780
shaker
Animals rotate back and forth around their longitudinal axes.
WB:cab
WB:cgc914
Any variation in the extremely thin elongated cytoplasmic filament, usually composed principally of actin protein to form a myofilament lattice, as in muscle cells compared to control (Wormatlas).
thin filament abnormal
C_elegans_phenotype_ontology
thin filament variant
WBPhenotype:0000781
body wall muscle thin filament variant
Any variation in the extremely thin elongated cytoplasmic filament, usually composed principally of actin protein to form a myofilament lattice, as in muscle cells compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of a robust elongated cytoplasmic filament composed principally of myosin protein compared to control animals. In C. elegans, thick filaments also contain paramyosin and twitchin (Wormatlas).
thick filament abnormal
C_elegans_phenotype_ontology
thick filament variant
WBPhenotype:0000782
body wall muscle thick filament variant
Animals exhibit variations in the form, structure or composition of a robust elongated cytoplasmic filament composed principally of myosin protein compared to control animals. In C. elegans, thick filaments also contain paramyosin and twitchin (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals lack the planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0000783
M line absent
Animals lack the planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Males exhibit variations in the time of onset or duration of the fertile period owing to differences in sperm competence and/or function compared to control animals.
male fertility abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000784
male fertility variant
Males exhibit variations in the time of onset or duration of the fertile period owing to differences in sperm competence and/or function compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular body part compared to control animals.
body part pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000785
body part pigmentation variant
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular body part compared to control animals.
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency along a particular body axis compared to control.
body axis pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000786
body axis pigmentation variant
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency along a particular body axis compared to control.
WB:WBPerson557
Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the posterior body axis compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000787
posterior pale
Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the posterior body axis compared to control.
WB:WBPerson557
Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the anterior body axis compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000788
anterior pale
Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the anterior body axis compared to control.
WB:WBPerson557
Animals respond to fluoxetine at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000789
fluoxetine hypersensitive
Animals respond to fluoxetine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000790
fluoxetine resistant
Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
The nose of an animal fails to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000791
nose resistant to fluoxetine
The nose of an animal fails to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of the anatomy contained in the anterior region, compared to control animals.
anterior region morphology variant
anterior body morphology abnormal
anterior region morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000792
anterior body morphology variant
Animals exhibit variations in the form, structure or composition of the anatomy contained in the anterior region, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of the anatomy contained in the posterior region, compared to control animals.
WBPhenotype:0001490
posterior region morphology variant
posterior body morphology abnormal
posterior region morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000793
posterior body morphology variant
Animals exhibit variations in the form, structure or composition of the anatomy contained in the posterior region, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
The posterior part of the worm exhibits a reduced girth compared to a control animal of the same developmental stage.
C_elegans_phenotype_ontology
WBPhenotype:0000794
posterior body thin
The posterior part of the worm exhibits a reduced girth compared to a control animal of the same developmental stage.
WB:WBPerson2021
WB:WBPerson557
Variations in the specific actions or reactions of one of the longitudinal axes of the extended body of the worm in response to external or internal stimuli compared to that observed in control animals (Wormatlas).
body axis behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000795
body axis behavior variant
Variations in the specific actions or reactions of one of the longitudinal axes of the extended body of the worm in response to external or internal stimuli compared to that observed in control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The movement of the posterior part of the worm is not coordinated with the rest of the body.
C_elegans_phenotype_ontology
WBPhenotype:0000796
posterior body uncoordinated
The movement of the posterior part of the worm is not coordinated with the rest of the body.
WB:cab
Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the tail of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas).
posterior body behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000797
posterior body behavior variant
Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the tail of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the head of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas).
anterior body behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000798
anterior body behavior variant
Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the head of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of an animal's anatomy contained in the anterior region over time, compared to control animals.
anterior region development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000799
anterior region development variant
Variations in the progression of an animal's anatomy contained in the anterior region over time, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of an animal's anatomy contained in the posterior region over time, compared to control animals.
posterior region development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000800
posterior region development variant
Variations in the progression of an animal's anatomy contained in the posterior region over time, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of an animal's anatomy contained in the ventral region over time, compared to control animals.
ventral region development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000801
ventral region development variant
Variations in the progression of an animal's anatomy contained in the ventral region over time, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of an animal's anatomy contained in the dorsal region over time, compared to control animals.
dorsal region development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000802
dorsal region development variant
Variations in the progression of an animal's anatomy contained in the dorsal region over time, compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of the anterior end of the animal over time from an initial condition to a later condition compared to control animals.
head development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000803
head development variant
Variations in the progression of the anterior end of the animal over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of the overall structure or appearance of the animal over time from an initial condition to a later condition compared to control animals.
body development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000804
body development variant
Variations in the progression of the overall structure or appearance of the animal over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the process whose specific outcome is the progression of the tail over time, from its formation to the mature structure, compared to control. The tail includes the posterior region that spans from the rectum to the end.
tail development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000805
tail development variant
Any variation in the process whose specific outcome is the progression of the tail over time, from its formation to the mature structure, compared to control. The tail includes the posterior region that spans from the rectum to the end.
WB:WBPerson2021
Hermaphrodites exhibit variations in the time of onset or duration of the fertile period, or variations in the production of viable offspring, including number and state of fertilized eggs laid, compared to controls.
hermaphrodite fertility abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000806
hermaphrodite fertility variant
Hermaphrodites exhibit variations in the time of onset or duration of the fertile period, or variations in the production of viable offspring, including number and state of fertilized eggs laid, compared to controls.
WB:WBPerson712
The descendants of the G1 or G2 exhibit altered developmental programs compared to their counterparts in control animals.
G lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000807
G lineages variant
The descendants of the G1 or G2 exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of the K precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
K lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000808
K lineage variant
The descendants of the K precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of a male specific precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
male specific lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000809
male specific lineage variant
The descendants of a male specific precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
Any variation in the progression of a blast cell (precursor cell) over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
blast cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000810
blast cell development variant
Any variation in the progression of a blast cell (precursor cell) over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Any variation in the progression of an epithelial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
epithelial cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000811
epithelial cell development variant
Any variation in the progression of an epithelial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Variations in the progression of the immature germ cell over time, from its formation from precursors to the mature structure (gamete) compared to control.
germ cell development abnormal
C_elegans_phenotype_ontology
germline development abnormal
WBPhenotype:0000812
germ cell development variant
Variations in the progression of the immature germ cell over time, from its formation from precursors to the mature structure (gamete) compared to control.
GO:0007281
WB:WBPerson2021
Any variation in the progression of a gland cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
gland cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000813
gland cell development variant
Any variation in the progression of a gland cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Any variation in the progression of a marginal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A marginal cell is a pharyngeal cell that connects the basement membrane to the apices of the triangle-shaped pharyngeal lumen.
marginal cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000814
marginal cell development variant
Any variation in the progression of a marginal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A marginal cell is a pharyngeal cell that connects the basement membrane to the apices of the triangle-shaped pharyngeal lumen.
WB:WBPerson2021
Any variation in the progression of a muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
muscle cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000815
muscle cell development variant
Any variation in the progression of a muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
neuron development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000816
neuron development variant
Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
GO:0048666
WB:WBPerson2021
Variations in the progression of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) over time from an initial condition to a later condition compared to control animals (Wormatlas).
uterine vulval cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000817
uterine vulval cell development variant
Variations in the progression of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) over time from an initial condition to a later condition compared to control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Activity characteristic of an adult worm is altered compared to control.
adult behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000818
adult behavior variant
Activity characteristic of an adult worm is altered compared to control.
WB:cab
Behavior characteristic of postembryonic stage(s) is altered compared to control.
postembryonic behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000819
postembryonic behavior variant
Behavior characteristic of postembryonic stage(s) is altered compared to control.
WB:cab
Activity characteristic of an embryo is altered compared to control.
embryonic behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000820
embryonic behavior variant
Activity characteristic of an embryo is altered compared to control.
WB:cab
Animals exhibit variations in sex-specific behaviors compared to control.
sexually dimorphic behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000821
sexually dimorphic behavior variant
Animals exhibit variations in sex-specific behaviors compared to control.
WB:WBPerson557
Any variation in the processes that govern the sexually dimorphic development of germline or somatic tissue compared to control.
sex determination abnormal
C_elegans_phenotype_ontology
sex specific development abnormal
WBPhenotype:0000822
sex determination variant
Any variation in the processes that govern the sexually dimorphic development of germline or somatic tissue compared to control.
WB:kmva
Nuclear divisions in the germ line are either expanded are reduced compared to control.
Glp
germ line proliferation abnormal
germline proliferation abnormal
C_elegans_phenotype_ontology
germ cell proliferation abnormal
WBPhenotype:0000823
germline proliferation variant
Nuclear divisions in the germ line are either expanded are reduced compared to control.
WB:cab
The descendants of an embryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
embryonic cell lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000824
embryonic cell lineage variant
The descendants of an embryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of a postembryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
postembryonic cell lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000825
postembryonic cell lineage variant
The descendants of a postembryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of H1 or H2 cells exhibit altered developmental programs compared to their counterparts in control animals.
H lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000826
H lineages variant
The descendants of H1 or H2 cells exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in control animals.
V lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000827
V lineages variant
The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of TL or TR cells exhibit altered developmental programs compared to their counterparts in control animals.
T lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000828
T lineages variant
The descendants of TL or TR cells exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in control animals.
Q lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000829
Q lineage variant
The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of the B cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
B lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000830
B lineage variant
The descendants of the B cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
Y lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000831
Y lineage variant
The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of the C blastomere exhibit altered developmental programs compared to their counterparts in control animals.
C lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000832
C lineage variant
The descendants of the C blastomere exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPaper00001584
WB:WBPerson2021
The descendants of the U cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
U lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000833
U lineage variant
The descendants of the U cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals.
E lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000834
E lineage variant
The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPaper00002870
WB:WBPerson2021
The descendants of the F cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
F lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000835
F lineage variant
The descendants of the F cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of a gonadal precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
gonadal lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000836
gonadal lineage variant
The descendants of a gonadal precursor cell exhibit altered developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of a gonadal precursor cell exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals.
hermaphrodite gonadal lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000837
hermaphrodite gonadal lineage variant
The descendants of a gonadal precursor cell exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of a gonadal precursor cell exhibit altered developmental programs in the male compared to their counterparts in control animals.
male gonadal lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000838
male gonadal lineage variant
The descendants of a gonadal precursor cell exhibit altered developmental programs in the male compared to their counterparts in control animals.
WB:WBPerson2021
Z1 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals.
Z1 hermaphrodite lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000839
Z1 hermaphrodite lineage variant
Z1 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals.
WB:WBPerson2021
Z4 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals.
Z4 hermaphrodite lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000840
Z4 hermaphrodite lineage variant
Z4 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals.
WB:WBPerson2021
Z1 descendents exhibit altered developmental programs in the male compared to their counterparts in control animals.
Z1 male lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000841
Z1 male lineage variant
Z1 descendents exhibit altered developmental programs in the male compared to their counterparts in control animals.
WB:WBPerson2021
Z4 descendants exhibit altered developmental programs in the male compared to their counterparts in control animals.
Z4 male lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000842
Z4 male lineage variant
Z4 descendants exhibit altered developmental programs in the male compared to their counterparts in control animals.
WB:WBPerson2021
The number of cross progeny sired by males is reduced compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000843
male mating efficiency reduced
The number of cross progeny sired by males is reduced compared to control.
WB:WBPaper00000179
WB:WBPaper00000608
WB:WBPerson557
Pharyngeal pumping is not influenced by serotonin treatment in the same manner as control animals.
serotonin induced pumping abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000844
serotonin induced pumping variant
Pharyngeal pumping is not influenced by serotonin treatment in the same manner as control animals.
WB:WBPerson2021
Animals exhibit variations in the response to the addition of levamisole compared to that observed in control animals. Levamisole is a cholinergic agonist.
levamisole response abnormal
C_elegans_phenotype_ontology
tetramisole response abnormal
WBPhenotype:0000845
levamisole response variant
Animals exhibit variations in the response to the addition of levamisole compared to that observed in control animals. Levamisole is a cholinergic agonist.
WB:WBPerson557
Animals exhibit variations in any physical or chemical process in the region of the vesicle-filled varicosities of the synapse compared to control.
presynaptic region physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000846
presynaptic region physiology variant
Animals exhibit variations in any physical or chemical process in the region of the vesicle-filled varicosities of the synapse compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals display variations in the distribution of the constituents that make up the synaptic machinery such as those required for priming, docking or fusion of vesicles at the active zone, compared to that observed in control animals.
presynaptic component localization abnormal
C_elegans_phenotype_ontology
synaptic component localization abnormal
synaptic machinery localization abnormal
WBPhenotype:0000847
presynaptic component localization variant
Animals display variations in the distribution of the constituents that make up the synaptic machinery such as those required for priming, docking or fusion of vesicles at the active zone, compared to that observed in control animals.
WB:WBPaper00027305
WB:WBPerson712
The developmental progression of an animal over time, from its formation to its mature structure is delayed compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000848
developmental delay
The developmental progression of an animal over time, from its formation to its mature structure is delayed compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for an amphid to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
amphid physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000849
amphid physiology variant
Animals exhibit variations in any physical or chemical process required for an amphid to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson557
Animal does not respond to stroking in the anterior body region with a hair or similar fiber compared to control. In C. elegans, the anterior region is defined as the body region that lies between the posterior bulb of the pharynx and the vulva.
C_elegans_phenotype_ontology
touch insensitive anterior body
WBPhenotype:0000850
touch resistant anterior body
Animal does not respond to stroking in the anterior body region with a hair or similar fiber compared to control. In C. elegans, the anterior region is defined as the body region that lies between the posterior bulb of the pharynx and the vulva.
WB:WBPaper00000502
WB:WBPaper00001705
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for the ciliated neuron to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
ciliated neuron physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000851
ciliated neuron physiology variant
Animals exhibit variations in any physical or chemical process required for the ciliated neuron to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Variations in the progression of a free-floating spherical cell lying in the pseudocoelomic cavity of animals that can endocytose many compounds, possibly for immune surveillance, over time from an initial condition to a later condition compared to control animals.
coelomocyte development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000852
coelomocyte development variant
Variations in the progression of a free-floating spherical cell lying in the pseudocoelomic cavity of animals that can endocytose many compounds, possibly for immune surveillance, over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum, compared to control.
intraflagellar transport abnormal
C_elegans_phenotype_ontology
IFT abnormal
WBPhenotype:0000853
intraflagellar transport variant
Variations in the bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum, compared to control.
GO:0042073
WB:WBPerson2021
Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is disrupted.
C_elegans_phenotype_ontology
ift defective
WBPhenotype:0000854
intraflagellar transport defective
Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is disrupted.
WB:WBPerson2021
Variations in the progression of the fluid-filled space which separates the body wall from internal organs over time from its initial formation to its mature form compared to control (Wormatlas).
pseudocoelom development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000855
pseudocoelom development variant
Variations in the progression of the fluid-filled space which separates the body wall from internal organs over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of a gland cell of the secretory-excretory system over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
excretory gland cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000856
excretory gland cell development variant
Any variation in the progression of a gland cell of the secretory-excretory system over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Variations in the progression of a protokidney cell with an internal lumen that is suggested to collect and secrete salt solutions outward via the excretory sinus, over time from an initial condition to a later condition compared to control animals.
excretory cell development abnormal
C_elegans_phenotype_ontology
excretory canal cell development abnormal
WBPhenotype:0000857
excretory cell development variant
Variations in the progression of a protokidney cell with an internal lumen that is suggested to collect and secrete salt solutions outward via the excretory sinus, over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of an interfacial epithelial cell which forms a lumen to receive the outflow of the excretory gland and excretory canal cells, over time from an initial condition to a later condition compared to control animals.
excretory duct cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000858
excretory duct cell development variant
Variations in the progression of an interfacial epithelial cell which forms a lumen to receive the outflow of the excretory gland and excretory canal cells, over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of an interfacial epithelial cell which links excretory duct to hypodermis, over time from an initial condition to a later condition compared to control animals.
excretory socket cell development abnormal
C_elegans_phenotype_ontology
excretory pore cell development abnormal
WBPhenotype:0000859
excretory socket cell development variant
Variations in the progression of an interfacial epithelial cell which links excretory duct to hypodermis, over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of muscle cells that lack transverse striations in its constituent fibers and are almost always involuntary, over time from an initial condition to a later condition compared to control animals.
nonstriated muscle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000860
nonstriated muscle development variant
Variations in the progression of muscle cells that lack transverse striations in its constituent fibers and are almost always involuntary, over time from an initial condition to a later condition compared to control animals.
GO:0051145
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the principal muscle cell type whose contractile activity generates body motion in the nematode over time compared to control. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas).
body wall muscle development abnormal
body wall muscle cell development abnormal
body wall muscle cell development variant
C_elegans_phenotype_ontology
muscle belly development abnormal
somatic muscle development abnormal
striated muscle development abnormal
WBPhenotype:0000861
body wall muscle development variant
Any variation in the progression of the principal muscle cell type whose contractile activity generates body motion in the nematode over time compared to control. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Worms appears turgid or swollen as a result of an excess number of eggs being retained in the uterus.
C_elegans_phenotype_ontology
WBPhenotype:0000862
bloated
Worms appears turgid or swollen as a result of an excess number of eggs being retained in the uterus.
WB:WBPerson2021
WB:WBPerson557
Males exhibit a reduction in the production of new individuals owing to defects in sperm competence and/or function compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000863
male fertility reduced
Males exhibit a reduction in the production of new individuals owing to defects in sperm competence and/or function compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Cessation of development during the initial period of elongation. In C. elegans, this period refers to the conversion of the bean-shaped embryo into the two-fold- shaped embryo.
C_elegans_phenotype_ontology
WBPhenotype:0000864
early elongation arrest
Cessation of development during the initial period of elongation. In C. elegans, this period refers to the conversion of the bean-shaped embryo into the two-fold- shaped embryo.
WB:WBPaper00027244
Animals exhibit variations in any physical or chemical process required for a amphid sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
amphid sheath cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000865
amphid sheath cell physiology variant
Animals exhibit variations in any physical or chemical process required for a amphid sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson557
Germ cells fail to undergo meiotic differentiation to form mature gametes.
C_elegans_phenotype_ontology
WBPhenotype:0000866
germ cell arrest
Germ cells fail to undergo meiotic differentiation to form mature gametes.
WB:WBPerson2021
WB:WBPerson557
Cessation of development during any stage occurring after fertilization and until hatching compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000867
embryonic arrest
Cessation of development during any stage occurring after fertilization and until hatching compared to control.
WB:WBPerson712
All parts of the animal are immobilized except for the head.
C_elegans_phenotype_ontology
WBPhenotype:0000868
paralyzed body
All parts of the animal are immobilized except for the head.
WB:cab
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000869
obsolete mitochondria morphology variant muscle
true
OBSOLETE.
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000870
obsolete mitochondria morphology variant epithelial
true
OBSOLETE.
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000871
obsolete connected mitochondria epithelial
true
OBSOLETE.
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000872
obsolete connected mitochodria muscle
true
OBSOLETE.
WB:WBPerson557
Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G1 phase of the mitotic cell cycle just before entry into S phase, compared to control cells.
G1 checkpoint abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000873
G1 checkpoint variant
Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G1 phase of the mitotic cell cycle just before entry into S phase, compared to control cells.
GO:0007089
WB:WBPerson557
WB:WBPerson712
Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G2 phase of the mitotic cell cycle just before entry into M phase, nuclear division, compared to control cells.
G2 checkpoint abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000874
G2 checkpoint variant
Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G2 phase of the mitotic cell cycle just before entry into M phase, nuclear division, compared to control cells.
GO:0000075
WB:WBPerson557
WB:WBPerson712
Mitotic cells exhibit variations during the passage through a cell cycle control point late in the S phase of the mitotic cell cycle, which ensures DNA replication is complete, compared to control cells.
S phase checkpoint abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000875
S phase checkpoint variant
Mitotic cells exhibit variations during the passage through a cell cycle control point late in the S phase of the mitotic cell cycle, which ensures DNA replication is complete, compared to control cells.
GO:0033314
WB:WBPerson712
Animals exhibit variations in their response to osmotic stress compared to that observed in control animals.
organism osmotic stress response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000876
organism osmotic stress response variant
Animals exhibit variations in their response to osmotic stress compared to that observed in control animals.
WB:WBPerson557
Any variation in the progression of a sheath cell of the amphid sensillum over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
amphid sheath cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000877
amphid sheath cell development variant
Any variation in the progression of a sheath cell of the amphid sensillum over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Any variation in the progression of a chemosensory neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
chemosensory neuron development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000878
chemosensory neuron development variant
Any variation in the progression of a chemosensory neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Animals exhibit variations in the processes that are required to maintain the length of telomeric DNA from generation to generation compared to control.
telomere length regulation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000879
telomere length regulation variant
Animals exhibit variations in the processes that are required to maintain the length of telomeric DNA from generation to generation compared to control.
GO:0032204
WB:WBPaper00031585
WB:WBPerson712
Any variation in the processes that influence the generation of neuronal extensions, that carry efferent (outgoing) action potentials from the cell body towards target cells compared to control.
axon development abnormal
C_elegans_phenotype_ontology
axonogenesis abnormal
WBPhenotype:0000880
axon development variant
Any variation in the processes that influence the generation of neuronal extensions, that carry efferent (outgoing) action potentials from the cell body towards target cells compared to control.
GO:0007409
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the placement of the microtuble-based dendritic projections in relation to the sensillum neuron, from that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000881
cilia mislocalized
Animals exhibit variations in the placement of the microtuble-based dendritic projections in relation to the sensillum neuron, from that observed in control animals.
WB:WBPerson712
Any variation in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body compared to control.
dendrite development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000882
dendrite development variant
Any variation in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body compared to control.
GO:0016358
WB:WBPerson2021
Variations in the progression of the major zone of overlapping axons in the head, which encircles the isthmus of the pharynx to form a tightly packed ring-like structure on the outside of the pharynx, over time from an initial condition to a later condition compared to control animals.
nerve ring development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000883
nerve ring development variant
Variations in the progression of the major zone of overlapping axons in the head, which encircles the isthmus of the pharynx to form a tightly packed ring-like structure on the outside of the pharynx, over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure or organization of either of a set of two ciliated wing neurons, AWBL or AWBR, of the amphid sensilla, compared to that observed in control animals.
AWB morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000884
WBbt:0005671.
AWB morphology variant
Animals exhibit variations in the structure or organization of either of a set of two ciliated wing neurons, AWBL or AWBR, of the amphid sensilla, compared to that observed in control animals.
WB:WBPaper00000938
WB:WBPerson712
Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control.
engulfment abnormal
C_elegans_phenotype_ontology
phagocytosis abnormal
WBPhenotype:0000885
engulfment variant
Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control.
GO:0043652
WB:WBPerson2021
Animals exhibit variations compared to a given control.
Abnormal
variant
C_elegans_phenotype_ontology
not WT
not wildtype
WBPhenotype:0000886
nematode phenotype
Animals exhibit variations compared to a given control.
WB:WBPerson557
Animals exhibit variations in hermaphrodite-specific behaviors compared to control.
hermaphrodite behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000887
hermaphrodite behavior variant
Animals exhibit variations in hermaphrodite-specific behaviors compared to control.
WB:WBPerson557
Animals exhibit variations in male-specific behaviors compared to control.
male behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000888
male behavior variant
Animals exhibit variations in male-specific behaviors compared to control.
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required to carry out sex-specific activities or to be able to perceive and respond to sex-specific stimuli compared to control.
sexually dimorphic physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000889
sexually dimorphic physiology variant
Animals exhibit variations in any physical or chemical process required to carry out sex-specific activities or to be able to perceive and respond to sex-specific stimuli compared to control.
WB:WBPerson557
Larva exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals.
larval pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000890
larval pigmentation variant
Larva exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals.
WB:WBPerson557
Adult animals appear unusually transparent when compared to control.
Clr
C_elegans_phenotype_ontology
WBPhenotype:0000891
clear adult
Adult animals appear unusually transparent when compared to control.
WB:WBPerson557
Nuclear divisions in the germ line of hermaphrodites are either expanded are reduced compared to control.
hermaphrodite germline proliferation abnormal
C_elegans_phenotype_ontology
hermaphrodite germ cell proliferation abnormal
hermaphrodite germ line proliferation abnormal
WBPhenotype:0000892
hermaphrodite germline proliferation variant
Nuclear divisions in the germ line of hermaphrodites are either expanded are reduced compared to control.
WB:WBPerson2021
Nuclear divisions in the germ line of male animals are either expanded are reduced compared to control.
male germline proliferation abnormal
C_elegans_phenotype_ontology
male germ cell proliferation abnormal
male germ line proliferation abnormal
WBPhenotype:0000893
male germline proliferation variant
Nuclear divisions in the germ line of male animals are either expanded are reduced compared to control.
WB:WBPerson2021
Variations in the ability of a relatively unspecialized cell to acquire the specialized features of a mature gamete compared to control.
germ cell differentiation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000894
germ cell differentiation variant
Variations in the ability of a relatively unspecialized cell to acquire the specialized features of a mature gamete compared to control.
WB:WBPerson2021
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000895
obsolete spermatocyte germ cell differentiation abnormal
true
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000896
obsolete oocyte germ cell differentiation abnormal
true
Variations in the material made up of fibers forming a framework and support structure for body tissues and organs compared to control.
connective tissue abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000897
connective tissue development variant
Variations in the material made up of fibers forming a framework and support structure for body tissues and organs compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the morphological appearance of blast cells compared to control animals.
blast cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000898
blast cell morphology variant
Any variation in the morphological appearance of blast cells compared to control animals.
WB:cab
Any variation in the morphological appearance of epithelial cells compared to control animals.
epithelial cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000899
epithelial cell morphology variant
Any variation in the morphological appearance of epithelial cells compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of germ cells compared to control animals.
germ cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000900
germ cell morphology variant
Any variation in the morphological appearance of germ cells compared to control animals.
WB:cab
Any variation in the morphological appearance of gland cells compared to control animals.
gland cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000901
gland cell morphology variant
Any variation in the morphological appearance of gland cells compared to control animals.
WB:cab
Any variation in the morphological appearance of intestinal cells compared to control animals.
intestinal cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000902
intestinal cell morphology variant
Any variation in the morphological appearance of intestinal cells compared to control animals.
WB:cab
Any variation in the morphological appearance of marginal cells compared to control animals.
marginal cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000903
marginal cell morphology variant
Any variation in the morphological appearance of marginal cells compared to control animals.
WB:cab
Any variation in the morphological appearance of muscle cells compared to control animals.
muscle cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000904
muscle cell morphology variant
Any variation in the morphological appearance of muscle cells compared to control animals.
WB:cab
Animals display variations in the structure or organization of components of the neuronal cell internal to the cell itself or in relation to the cellular environment compared to control. A neuron is a major cell type of nervous tissue specialized for transmission of information in the form of patterns of impulses.
neuron morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000905
WBbt:0003679.
neuron morphology variant
Animals display variations in the structure or organization of components of the neuronal cell internal to the cell itself or in relation to the cellular environment compared to control. A neuron is a major cell type of nervous tissue specialized for transmission of information in the form of patterns of impulses.
WB:WBPerson712
WB:cab
Animals exhibit variations in the form, structure or composition of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) compared to control animals (Wormatlas).
uterine vulval cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000906
uterine vulval cell morphology variant
Animals exhibit variations in the form, structure or composition of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) compared to control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the structural appearance of the caudal opening of the rectum in the tail compared to control animals.
anus morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000907
anus morphology variant
Any variation in the structural appearance of the caudal opening of the rectum in the tail compared to control animals.
WB:WBPerson557
Any variation in the structural appearance of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) compared to control animals.
WBPhenotype:0000343
cloaca morphology abnormal
cloacal morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000908
cloacal morphology variant
Any variation in the structural appearance of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) compared to control animals.
WB:WBPerson557
Any variation in the structure or appearance of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas).
pharyngeal intestinal valve morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000909
pharyngeal intestinal valve morphology variant
Any variation in the structure or appearance of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas).
WB:WBPerson557
Any variation in the morphological appearance of the rectum compared to control animals.
rectal morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000910
rectal morphology variant
Any variation in the morphological appearance of the rectum compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of coelomocytes compared to control animals.
coelomocyte morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000911
coelomocyte morphology variant
Any variation in the morphological appearance of coelomocytes compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of pericellular components compared to control animals.
pericellular component morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000912
pericellular component morphology variant
Any variation in the morphological appearance of pericellular components compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of the basal lamina compared to control animals.
basal lamina morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000913
basal lamina morphology variant
Any variation in the morphological appearance of the basal lamina compared to control animals.
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas).
excretory gland cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000914
excretory gland cell morphology variant
Animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Adults show deficiencies in chroma resulting in increased translucency.
C_elegans_phenotype_ontology
WBPhenotype:0000915
pale adult
Adults show deficiencies in chroma resulting in increased translucency.
WB:WBPerson2021
WB:WBPerson557
Any variation in the morphological appearance of the excretory cell compared to control animals.
excretory cell morphology abnormal
C_elegans_phenotype_ontology
excretory canal cell morphology abnormal
WBPhenotype:0000916
excretory cell morphology variant
Any variation in the morphological appearance of the excretory cell compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of the excretory duct cell compared to control animals.
excretory duct cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000917
excretory duct cell morphology variant
Any variation in the morphological appearance of the excretory duct cell compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of the excretory socket cell compared to control animals.
excretory socket cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000918
excretory socket cell morphology variant
Any variation in the morphological appearance of the excretory socket cell compared to control animals.
WB:WBPerson557
Any variation in the progression of the region of a body wall muscle cell that contains the myofilament lattice (adjacent to the hypodermis) over time, from its initial state to the fully differentiated state compared to control.
spindle body wall muscle cell development abnormal
C_elegans_phenotype_ontology
filament lattice body wall muscle cell development abnormal
spindle body wall muscle cell development variant
WBPhenotype:0000919
body wall muscle cell spindle development variant
Any variation in the progression of the region of a body wall muscle cell that contains the myofilament lattice (adjacent to the hypodermis) over time, from its initial state to the fully differentiated state compared to control.
WB:WBPaper00000461
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000920
obsolete body wall muscle cell development variant
true
OBSOLETE.
WB:WBPerson557
Variations in the progression of muscle cells that contain fibers that are divided by transverse bands into striations, over time from an initial condition to a later condition compared to control animals.
striated muscle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000921
Possible XP.
striated muscle development variant
Variations in the progression of muscle cells that contain fibers that are divided by transverse bands into striations, over time from an initial condition to a later condition compared to control animals.
GO:0055002
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of somatic (striated) muscles that run longitudinally in males over time from its initial formation to its mature form compared to control. In C. elegans males have 3 additional sets of sex-specific longitudinal muscles (anterior and posterior outer, anterior and posterior inner, and caudal) that contribute to the body wall musculature (Wormatlas).
male longitudinal muscle development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000922
male longitudinal muscle development variant
Any variation in the progression of somatic (striated) muscles that run longitudinally in males over time from its initial formation to its mature form compared to control. In C. elegans males have 3 additional sets of sex-specific longitudinal muscles (anterior and posterior outer, anterior and posterior inner, and caudal) that contribute to the body wall musculature (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the morphological appearance of the nonstriated muscle compared to control animals.
nonstriated muscle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000923
nonstriated muscle morphology variant
Any variation in the morphological appearance of the nonstriated muscle compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of the striated muscle compared to control animals.
striated muscle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000924
striated muscle morphology variant
Any variation in the morphological appearance of the striated muscle compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of the sex muscles compared to control animals.
sex muscle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000925
sex muscle morphology variant
Any variation in the morphological appearance of the sex muscles compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of the body wall muscle compared to control animals.
body wall muscle morphology abnormal
C_elegans_phenotype_ontology
Dim
WBPhenotype:0000926
body wall muscle morphology variant
Any variation in the morphological appearance of the body wall muscle compared to control animals.
WB:WBPerson557
Any variation in the morphological appearance of the male longitudinal muscle compared to control animals.
male longitudinal muscle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000927
male longitudinal muscle morphology variant
Any variation in the morphological appearance of the male longitudinal muscle compared to control animals.
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required to carry out male-specific activities or to be able to perceive and respond to male-specific stimuli compared to control.
male physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000928
male physiology variant
Animals exhibit variations in any physical or chemical process required to carry out male-specific activities or to be able to perceive and respond to male-specific stimuli compared to control.
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required to carry out hermaphrodite-specific activities or to be able to perceive and respond to hermaphrodite-specific stimuli compared to control.
hermaphrodite physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000929
hermaphrodite physiology variant
Animals exhibit variations in any physical or chemical process required to carry out hermaphrodite-specific activities or to be able to perceive and respond to hermaphrodite-specific stimuli compared to control.
WB:WBPerson557
Variations in the progression of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, over time from an initial condition to a later condition compared to control animals.
sexually dimorphic development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000930
sexually dimorphic development variant
Variations in the progression of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their response to bisphenol A compared to that observed in control animals.
bisphenol A response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000931
bisphenol A response variant
Animals exhibit variations in their response to bisphenol A compared to that observed in control animals.
WB:WBPerson557
Animals respond to bisphenol A at a lower concentration or a shorter exposure time compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000932
bisphenol A hypersensitive
Animals respond to bisphenol A at a lower concentration or a shorter exposure time compared to control animals.
WB:WBPerson557
The descendants of the MS blastomere exhibit any variation in developmental programs compared to their counterparts in control animals.
MS lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000933
MS lineage variant
The descendants of the MS blastomere exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPaper00002330
WB:WBPerson2021
Animals exhibit variations in the form, structure or composition of any of its parts during a given developmental stage compared to control animals.
developmental morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000934
developmental morphology variant
Animals exhibit variations in the form, structure or composition of any of its parts during a given developmental stage compared to control animals.
WB:WBPerson2021
WB:WBPerson557
The descendants of the D blastomere exhibit any variation in developmental programs compared to their counterparts in control animals.
D lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000935
D lineage variant
The descendants of the D blastomere exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPaper00002572
WB:WBPerson2021
The descendants of the P4 blastomere exhibit any variation in developmental programs compared to their counterparts in control animals.
P4 lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000936
P4 lineage variant
The descendants of the P4 blastomere exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of the W precursor cell exhibit any variation in developmental programs compared to their counterparts in control animals.
W lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000937
W lineage variant
The descendants of the W precursor cell exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals.
male V lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000938
male V lineages variant
The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of TL or TR cells in male animals exhibit any variation in developmental programs compared to their counterparts in control animals.
male T lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000939
male T lineages variant
The descendants of TL or TR cells in male animals exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of any of the P precursor cells (P1-P12) in male animals exhibit any variation in developmental programs compared to their counterparts in control animals.
male P lineages abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000940
male P lineages variant
The descendants of any of the P precursor cells (P1-P12) in male animals exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
The descendants of the M precursor cell in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals.
male M lineage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000941
male M lineage variant
The descendants of the M precursor cell in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals.
WB:WBPerson2021
Any variation in the progression of an accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. An accessory cell supports sensory neurons.
accessory cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000942
accessory cell development variant
Any variation in the progression of an accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. An accessory cell supports sensory neurons.
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of a cluster of neuron cell bodies (somata) over time from its initial formation to its mature form compared to control.
ganglion development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000943
ganglion development variant
Any variation in the progression of a cluster of neuron cell bodies (somata) over time from its initial formation to its mature form compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure compared to control.
neurite development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000944
neurite development variant
Variations in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure compared to control.
GO:0031175
WB:WBPerson2021
Any variation in the progression of a dense feltwork of interwoven cytoplasmic processes of nerve cells (dendrites and axons) and support cells, over time from an initial condition to a later condition, compared to control.
neuropil development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000945
neuropil development variant
Any variation in the progression of a dense feltwork of interwoven cytoplasmic processes of nerve cells (dendrites and axons) and support cells, over time from an initial condition to a later condition, compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the progression of a set of interacting or interdependent entities forming the pharyngeal nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses.
pharyngeal nervous system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000946
pharyngeal nervous system development variant
Variations in the progression of a set of interacting or interdependent entities forming the pharyngeal nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses.
GO:0007420
WB:WBPerson2021
WB:WBPerson557
Variations in the form, structure or composition of the material made up of fibers forming a framework and support structure for body tissues and organs compared to control.
connective tissue morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000947
connective tissue morphology variant
Variations in the form, structure or composition of the material made up of fibers forming a framework and support structure for body tissues and organs compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the appearance or structure of the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells compared to control (Wormatlas).
cuticle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000948
cuticle morphology variant
Any variation in the appearance or structure of the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the appearance of the body cavity compared to control. In C. elegans , an aberrancy in the psedocoelom can involve an accumulation of fluids or fluorescent reporters.
pseudocoelom morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000949
pseudocoelom morphology variant
Any variation in the appearance of the body cavity compared to control. In C. elegans , an aberrancy in the psedocoelom can involve an accumulation of fluids or fluorescent reporters.
WB:WBPerson712
Any variation in the progression of a neuronal sheath cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A neuronal sheath cell is a structural cell that forms a specialized environment surrounding the sensory endings of a neuron.
neuronal sheath cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000950
neuronal sheath cell development variant
Any variation in the progression of a neuronal sheath cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A neuronal sheath cell is a structural cell that forms a specialized environment surrounding the sensory endings of a neuron.
WB:WBPerson2021
Any variation in the progression of a socket cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
socket cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000951
socket cell development variant
Any variation in the progression of a socket cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.
WB:WBPerson2021
Any variation in the progression of a cluster of neuron somata located close to the nerve ring over time from its initial formation to its mature form compared to control (Wormatlas).
anterior ganglion development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000952
anterior ganglion development variant
Any variation in the progression of a cluster of neuron somata located close to the nerve ring over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the ganglion that lies dorsally beside the nerve ring in the head over time from its initial formation to its mature form compared to control. In C. elegans, It contains neuron cell bodies that send their neuronal processes into the ring and longitudinal nerves, but form no local neuropil separate from the nerve ring. The dorsal ganglion is in close contact with the dorsal hypodermal cord (Wormatlas).
dorsal ganglion development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000953
dorsal ganglion development variant
Any variation in the progression of the ganglion that lies dorsally beside the nerve ring in the head over time from its initial formation to its mature form compared to control. In C. elegans, It contains neuron cell bodies that send their neuronal processes into the ring and longitudinal nerves, but form no local neuropil separate from the nerve ring. The dorsal ganglion is in close contact with the dorsal hypodermal cord (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the ganglion which lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge over time from its initial formation to its mature form compared to control (Wormatlas).
dorsorectal ganglia development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000954
dorsorectal ganglia development variant
Any variation in the progression of the ganglion which lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the left and right lateral ganglia which lie beside the nerve ring in the head over time from its initial formation to its mature form compared to control (Wormatlas).
lateral ganglia development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000955
lateral ganglia development variant
Any variation in the progression of the left and right lateral ganglia which lie beside the nerve ring in the head over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the left and right lumbar ganglia which lie behind the pre-anal ganglion in the tail, in lateral positions over time from its initial formation to its mature form compared to control (Wormatlas).
lumbar ganglia development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000956
lumbar ganglia development variant
Any variation in the progression of the left and right lumbar ganglia which lie behind the pre-anal ganglion in the tail, in lateral positions over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the neuron somata associated with the post-deirid over time from its initial formation to its mature form compared to control (Wormatlas).
posterior lateral ganglion development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000957
posterior lateral ganglion development variant
Any variation in the progression of the neuron somata associated with the post-deirid over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the ganglion which lies at the posterior limit of the ventral nerve cord in the tail over time from its initial formation to its mature form compared to control (Wormatlas).
preanal ganglion development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000958
preanal ganglion development variant
Any variation in the progression of the ganglion which lies at the posterior limit of the ventral nerve cord in the tail over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the ganglion which lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore over time from its initial formation to its mature form compared to control (Wormatlas).
retrovesicular ganglion development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000959
retrovesicular ganglion development variant
Any variation in the progression of the ganglion which lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the ganglion which lies ventrally beside the nerve ring in the head, just anterior of the retrovesicular ganglion over time from its initial formation to its mature form compared to control (Wormatlas).
ventral ganglion development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000960
ventral ganglion development variant
Any variation in the progression of the ganglion which lies ventrally beside the nerve ring in the head, just anterior of the retrovesicular ganglion over time from its initial formation to its mature form compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
pattern of transgene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000961
pattern of transgene expression variant
Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WB:WBPerson557
Any variation in the measured expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
level of transgene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000962
level of transgene expression variant
Any variation in the measured expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WB:WBPerson557
Males exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism compared to control animals.
male pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000963
male pigmentation variant
Males exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism compared to control animals.
WB:WBPerson557
Animals fail to respond to the concentration of DMPP that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0000964
DMPP resistant
Animals fail to respond to the concentration of DMPP that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals exhibit variations in the programmed cell death pathway that is triggered in cells other than germ cells and that is not subject to upstream checkpoint regulation.
somatic cell death abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000965
somatic cell death variant
Animals exhibit variations in the programmed cell death pathway that is triggered in cells other than germ cells and that is not subject to upstream checkpoint regulation.
WB:WBPaper00032243
WB:WBPerson712
Progressive decrease in brood size culminating, over generations, in the loss of reproductive ability and thus becoming effectively sterile.
Mrt
C_elegans_phenotype_ontology
WBPhenotype:0000966
germline mortal
Progressive decrease in brood size culminating, over generations, in the loss of reproductive ability and thus becoming effectively sterile.
WB:WBPaper00003886
WB:WBPaper00027026
WB:WBPerson712
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000967
In the WS193 and WS200 versions of WormBase WBPhenotype:0000967 has term name "male tail spike"; In some older records the term ID WBPhenotype:0000967 had the term name "male distal tip cell behavior abnormal", which may reflect an earlier (now deprecated) usage of the term ID.
obsolete male tail spike
true
Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the tail compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0000968
tail spike variant
Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the tail compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure, organization or placement of the cells that support sensory neurons, compared to that observed in control animals. In C. elegans, this category collectively refers to socket cells, sheath cells, and structural cells, or their processes.
accessory cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000969
WBbt:0005762.
accessory cell morphology variant
Animals exhibit variations in the structure, organization or placement of the cells that support sensory neurons, compared to that observed in control animals. In C. elegans, this category collectively refers to socket cells, sheath cells, and structural cells, or their processes.
WB:WBPerson557
WB:WBPerson712
Embryos exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals .
embryonic pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000970
embryonic pigmentation variant
Embryos exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals .
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the anterior body axis compared to control.
anterior pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000971
anterior pigmentation variant
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the anterior body axis compared to control.
WB:WBPerson557
Animals exhibit variations in the structure or composition of the glia-like support cell of neuronal sensilla that ensheathes the dendrite tips and or processes of neurons, from that observed in control animals. In C. elegans, sheath cells have highly invaginated and vesiculated surfaces, which provide a specialized environment for dendritic structures.
WBPhenotype:0001529
sensilium sheath cell morphology variant
neuronal sheath cell morphology abnormal
sensilium sheath cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000972
neuronal sheath cell morphology variant
Animals exhibit variations in the structure or composition of the glia-like support cell of neuronal sensilla that ensheathes the dendrite tips and or processes of neurons, from that observed in control animals. In C. elegans, sheath cells have highly invaginated and vesiculated surfaces, which provide a specialized environment for dendritic structures.
WB:WBPaper00000822
WB:WBPaper00000938
WB:WBPerson712
Animals exhibit an increased frequency of exchange of genetic material between non-sister chromatids of a pair of homologues.
C_elegans_phenotype_ontology
WBPhenotype:0000973
homologous recombination increased
Animals exhibit an increased frequency of exchange of genetic material between non-sister chromatids of a pair of homologues.
GO:0007131
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required by a subset of interfacial cells to carry out its normal function or be able to perceive and respond to stimuli, compared to control. It can refer to socket cells, sheath cells and structural cells or their processes (Wormatlas).
accessory cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000974
accessory cell physiology variant
Animals exhibit variations in any physical or chemical process required by a subset of interfacial cells to carry out its normal function or be able to perceive and respond to stimuli, compared to control. It can refer to socket cells, sheath cells and structural cells or their processes (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for a neuronal sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
neuronal sheath cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000975
neuronal sheath cell physiology variant
Animals exhibit variations in any physical or chemical process required for a neuronal sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson557
Any variation in the developmental process that results in the creation of defined areas or spaces within the ventral cord to which cells respond and eventually are instructed to differentiate compared to control.
ventral cord patterning abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000976
ventral cord patterning variant
Any variation in the developmental process that results in the creation of defined areas or spaces within the ventral cord to which cells respond and eventually are instructed to differentiate compared to control.
GO:0007389
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of the components of the gonad that are separate from the germline proper compared to control animals.
somatic gonad morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000977
somatic gonad morphology variant
Animals exhibit variations in the form, structure or composition of the components of the gonad that are separate from the germline proper compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the spermatheca to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
spermatheca physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000978
spermatheca physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the spermatheca to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Animals exhibit defects in any physical or chemical process involved in the dilation of the distal spermatheca which is required for the oocyte exit from the gonad arm.
C_elegans_phenotype_ontology
WBPhenotype:0000979
spermatheca dilation defective
Animals exhibit defects in any physical or chemical process involved in the dilation of the distal spermatheca which is required for the oocyte exit from the gonad arm.
WB:WBPaper00003371
WB:WBPerson2021
WB:WBPerson557
Any variation in the muscle contractions that control feeding compared to control. Contractions are necessary for bacterial uptake from the surrounding environment.
pharyngeal contraction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000980
pharyngeal contraction variant
Any variation in the muscle contractions that control feeding compared to control. Contractions are necessary for bacterial uptake from the surrounding environment.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids (non-motile sperm) compared to control.
WBPhenotype:0000713
spermatocyte division variant
spermatocyte division abnormal
spermatocyte meiosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000981
spermatocyte meiosis variant
Animals exhibit variations in the meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids (non-motile sperm) compared to control.
GO:0048137
WB:WBPaper00027300
WB:WBPerson2021
Animals exhibit variations in the ability of a relatively unspecialized spermatocyte to acquire the properties of a spermatid cell compared to control.
spermatid maturation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000982
spermatid maturation variant
Animals exhibit variations in the ability of a relatively unspecialized spermatocyte to acquire the properties of a spermatid cell compared to control.
WB:WBPaper00027300
WB:WBPerson2021
Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) during sexual reproduction.
C_elegans_phenotype_ontology
WBPhenotype:0000983
fertilization defective
Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) during sexual reproduction.
GO:0009566
WB:WBPerson2021
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the posterior body axis compared to control.
posterior pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000984
posterior pigmentation variant
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the posterior body axis compared to control.
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for the blast cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals.
blast cell physiology variant
blast cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000985
blast cell physiology phenotype
Animals exhibit variations in any physical or chemical process required for the blast cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals.
GO:0009987
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the epithelial cell to carry out its normal functions or activities, compared to control animals.
epithelial cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000986
epithelial cell physiology variant
Animals exhibit variations in any physical or chemical process required for the epithelial cell to carry out its normal functions or activities, compared to control animals.
GO:0009987
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the germ cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals.
germ cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000987
germ cell physiology variant
Animals exhibit variations in any physical or chemical process required for the germ cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals.
GO:0009987
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the gland cell to carry out its normal functions or activities or be able to perceive and respond to signals, compared to control animals.
gland cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000988
gland cell physiology variant
Animals exhibit variations in any physical or chemical process required for the gland cell to carry out its normal functions or activities or be able to perceive and respond to signals, compared to control animals.
GO:0009987
WB:WBPerson557
WB:WBPerson712
Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for a marginal cell to carry out its normal function and activities or be able to perceive and respond to stimuli.
marginal cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000989
marginal cell physiology variant
Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for a marginal cell to carry out its normal function and activities or be able to perceive and respond to stimuli.
GO:0009987
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for the muscle cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
muscle cell physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0000990
muscle cell physiology variant
Animals exhibit variations in any physical or chemical process required for the muscle cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
GO:0009987
WB:WBPerson557
WB:WBPerson712
OBSOLETE: Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes.
C_elegans_phenotype_ontology
WBPhenotype:0000991
obsolete neuron physiology variant
true
OBSOLETE: Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes.
WB:WBPaper00032221
WB:WBPerson712
Failure to execute the characteristic response to high concentrations of sodium chloride solution. C. elegans typically avoids high concentrations of sodium chloride solution.
C_elegans_phenotype_ontology
WBPhenotype:0000992
high sodium chloride concentration osmotic avoidance defective
Failure to execute the characteristic response to high concentrations of sodium chloride solution. C. elegans typically avoids high concentrations of sodium chloride solution.
WB:WBPerson2021
Animals fail to contract the anal depressor muscle.
Exp
C_elegans_phenotype_ontology
WBPhenotype:0000993
anal depressor contraction defect
Animals fail to contract the anal depressor muscle.
WB:WBPaper00001256
Any variations in the contraction of the enteric muscles that are involved in defecation motor program compared to control.
intestinal contractions abnormal
C_elegans_phenotype_ontology
Emc
enteric muscle contraction variant
WBPhenotype:0000994
intestinal contractions variant
Any variations in the contraction of the enteric muscles that are involved in defecation motor program compared to control.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0000995
WBPhenotype:0000995 an alt_id for "sodium chloride chemotaxis defective" (WBPhenotype:0001084) (WS193 OBO and WS200 site) AND has term name "pos body wall contraction defect" (dump_phenotype_ace.pl)
true
Animals exhibit defects in the expulsion of gut contents. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion.
Emc
Exp
C_elegans_phenotype_ontology
WBPhenotype:0000996
expulsion defective
Animals exhibit defects in the expulsion of gut contents. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion.
WB:WBPaper00001256
WB:WBPaper00031246
WB:WBPerson712
Animals tend to track and stay within low temperature environments.
C_elegans_phenotype_ontology
WBPhenotype:0000997
cryophilic
Animals tend to track and stay within low temperature environments.
WB:WBPerson2021
WB:WBPerson557
Animals tend to track and stay within high temperature environments.
C_elegans_phenotype_ontology
WBPhenotype:0000998
thermophilic
Animals tend to track and stay within high temperature environments.
WB:WBPerson2021
WB:WBPerson557
The responses of an animal towards temperature are not influenced by its cultivation temperature.
C_elegans_phenotype_ontology
WBPhenotype:0000999
athermotactic
The responses of an animal towards temperature are not influenced by its cultivation temperature.
WB:WBPerson363
Any variation in the behavior characteristic during certain developmental stage(s) compared to control.
developmental behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001000
developmental behavior variant
Any variation in the behavior characteristic during certain developmental stage(s) compared to control.
WB:cab
Variations in the specific actions or reactions of dauer stage animals in response to external or internal stimuli compared to that observed in control animals.
dauer behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001001
dauer behavior variant
Variations in the specific actions or reactions of dauer stage animals in response to external or internal stimuli compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the specific actions or reactions of the head muscles in response to external or internal stimuli compared to that observed in control animals.
head muscle behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001002
head muscle behavior variant
Variations in the specific actions or reactions of the head muscles in response to external or internal stimuli compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals die at the L4 stage of the life cycle.
Let
Lvl
C_elegans_phenotype_ontology
WBPhenotype:0001003
L4 lethal
Animals die at the L4 stage of the life cycle.
WB:WBPerson2021
Any variation in the relaxation of pharyngeal muscles after contraction events compared to control.
pharyngeal relaxation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001004
pharyngeal relaxation variant
Any variation in the relaxation of pharyngeal muscles after contraction events compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the spontaneous or induced backward crawling locomotion of an animal compared to control.
backward locomotion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001005
backward locomotion variant
Variations in the spontaneous or induced backward crawling locomotion of an animal compared to control.
WB:WBPerson2021
WB:WBPerson557
The number of coordinated contraction-relaxation cycles (pumps) exhibited by the pharyngeal muscle deviates from that observed for control animals.
pharyngeal pumping rate abnormal
C_elegans_phenotype_ontology
feeding rate dynamics abnormal
pumping rate dynamics abnormal
WBPhenotype:0001006
pharyngeal pumping rate variant
The number of coordinated contraction-relaxation cycles (pumps) exhibited by the pharyngeal muscle deviates from that observed for control animals.
WB:WBPaper00001709
WB:WBPerson712
Unclassified abnormality in the inviable one- to four-cell embryo.
Emb
Oth
other abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001007
other abnormality early emb
Unclassified abnormality in the inviable one- to four-cell embryo.
WB:cab
Variations in the progression of a set of interacting or interdependent entities forming the male nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses.
male nervous system development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001008
male nervous system development variant
Variations in the progression of a set of interacting or interdependent entities forming the male nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses.
GO:0007420
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular developmental stage of the amimal compared to control animals.
developmental pigmentation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001009
developmental pigmentation variant
Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular developmental stage of the amimal compared to control animals.
WB:WBPerson557
Animals appear unusually transparent when compared to control.
Clr
C_elegans_phenotype_ontology
WBPhenotype:0001010
clear
Animals appear unusually transparent when compared to control.
WB:WBPaper00004402
WB:WBPaper00005654
WB:cab
Population of unhatched eggs exhibit a complex combination of defects that do not match other class definitions.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001011
complex phenotype early emb
Population of unhatched eggs exhibit a complex combination of defects that do not match other class definitions.
WB:cab
WB:cgc7141
Animals exhibit variations in their response to disease causing agents, compared to control. Pathogen response includes prevention, damage control and recovery from the infection caused by the attack.
bacterial load variant
organism pathogen response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001012
organism pathogen response variant
Animals exhibit variations in their response to disease causing agents, compared to control. Pathogen response includes prevention, damage control and recovery from the infection caused by the attack.
GO:0006952
WB:WBPaper00032196
WB:WBPerson2021
WB:WBPerson712
Animals are more prone to infection compared to control.
Esp
C_elegans_phenotype_ontology
enhanced susceptibility to pathogens
WBPhenotype:0001013
pathogen susceptibility increased
Animals are more prone to infection compared to control.
WB:WBPaper00005370
WB:WBPaper00024299
WB:cab
Animals are less prone to infection compared to control.
C_elegans_phenotype_ontology
pathogen susceptibility decreased
WBPhenotype:0001014
pathogen resistance increased
Animals are less prone to infection compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during any development stages compared to control animals.
developmental growth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001015
developmental growth variant
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during any development stages compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the larval stages compared to control animals.
larval growth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001016
larval growth variant
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the larval stages compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the adult stage compared to control animals.
adult growth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001017
adult growth variant
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the adult stage compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation that disrupts the cytoplasmic division of a cell during embryonic development compared to control.
Cyk
C_elegans_phenotype_ontology
WBPhenotype:0001018
cytokinesis variant emb
Any variation that disrupts the cytoplasmic division of a cell during embryonic development compared to control.
GO:0000910
WB:WBPerson2021
Animals arrest during the stage between early and late larval development. In C. elegans, mid larval arrest occurs during the L2 to L3 stages of development.
C_elegans_phenotype_ontology
WBPhenotype:0001019
mid larval arrest
Animals arrest during the stage between early and late larval development. In C. elegans, mid larval arrest occurs during the L2 to L3 stages of development.
WB:cab
Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation.
Emb
Led
C_elegans_phenotype_ontology
WBPhenotype:0001020
embryonic lethal late emb
Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation.
WB:WBPerson101
Genetically male animals exhibit deviations in the sexual program specific to males. In C. elegans, this often refers to XO animals being transformed into fertile hermaphrodites.
Her
male sexual development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001021
male sexual development variant
Genetically male animals exhibit deviations in the sexual program specific to males. In C. elegans, this often refers to XO animals being transformed into fertile hermaphrodites.
WB:WBPaper00000498
WB:WBPerson2021
Genetically hermaphrodite animals exhibit deviations in the sexual program specific to hermaphrodites. In C. elegans, this refers to XX animals that develop as males or intersexuals instead of self-fertile hermaphrodites.
hermaphrodite sexual development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001022
hermaphrodite sexual development variant
Genetically hermaphrodite animals exhibit deviations in the sexual program specific to hermaphrodites. In C. elegans, this refers to XX animals that develop as males or intersexuals instead of self-fertile hermaphrodites.
WB:WBPerson2021
Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, from that observed for control animals.
sexually dimorphic morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001023
sexually dimorphic morphology variant
Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, from that observed for control animals.
GO:0009886
WB:WBPerson712
Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a male in the population, from that observed for control males.
male morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001024
male morphology variant
Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a male in the population, from that observed for control males.
GO:0009886
WB:WBPerson712
Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a hermaphrodite in the population, from that observed for control hermaphrodites.
hermaphrodite morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001025
hermaphrodite morphology variant
Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a hermaphrodite in the population, from that observed for control hermaphrodites.
GO:0009886
WB:WBPerson712
Animals exhibit variations in the form, structure or composition of the membrane enclosed organelle which contains most of the cell's genetic material during the early embryonic stage compared to control animals (Wormatlas).
Emb
Nmo
C_elegans_phenotype_ontology
WBPhenotype:0001026
nuclear morphology variation early emb
Animals exhibit variations in the form, structure or composition of the membrane enclosed organelle which contains most of the cell's genetic material during the early embryonic stage compared to control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Embryos show defects in the placement of the nucleus to a specific location within the cell.
Emb
Npo
nuclear position abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001027
nuclear position defective early emb
Embryos show defects in the placement of the nucleus to a specific location within the cell.
WB:WBPerson2021
WB:WBPerson557
The morphological appearance of nuclei differs from control animals.
nuclear appearance abnormal
C_elegans_phenotype_ontology
nuclear morphology variant
WBPhenotype:0001028
nuclear appearance variant
The morphological appearance of nuclei differs from control animals.
WB:cab
Animals exhibit an uneven distribution of biochromes or any other substances that cause disparate transparency/translucency compared to control animals.
Pch
C_elegans_phenotype_ontology
WBPhenotype:0001029
patchy coloration
Animals exhibit an uneven distribution of biochromes or any other substances that cause disparate transparency/translucency compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any deficiency in the lipid bilayer, the equivalent of the nuclear envelope, that surrounds each pronucleus within gametes and within the early zygote after pronuclear reformation (Wormatlas).
Emb
Pna
pronuclear envelope abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001030
pronuclear envelope defective early emb
Any deficiency in the lipid bilayer, the equivalent of the nuclear envelope, that surrounds each pronucleus within gametes and within the early zygote after pronuclear reformation (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the movement/fusion of pronuclei in the fertilized oocyte compared to control. For example, lack of male pronuclear migration, female pronuclear migration variable, sometimes multiple female pronuclei, no or small spindle.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001031
pronuclear migration reduced early emb
Any variation in the movement/fusion of pronuclei in the fertilized oocyte compared to control. For example, lack of male pronuclear migration, female pronuclear migration variable, sometimes multiple female pronuclei, no or small spindle.
WB:cab
WB:cgc7141
Variations in the specific actions or reactions of a larvae in response to external or internal stimuli compared to that observed in control animals.
larval behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001032
larval behavior variant
Variations in the specific actions or reactions of a larvae in response to external or internal stimuli compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the spatial pattern of proliferation and differentiation in the germ line compared to control. In C. elegans, this refers to an ectopic mass of proliferating germ cells that occupies the proximal adult germ line, a region normally occupied by gametes.
Pro
proximal germ cell proliferation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001033
proximal germ cell proliferation variant
Any variation in the spatial pattern of proliferation and differentiation in the germ line compared to control. In C. elegans, this refers to an ectopic mass of proliferating germ cells that occupies the proximal adult germ line, a region normally occupied by gametes.
WB:WBPaper00006484
WB:WBPerson2021
The morphology of pronuclei and nuclei are defective in the early embryo. In C. elegans, this defect is often characterized by pronuclei and nuclei that are small or missing altogether and are often accompanied by spindle defects.
Emb
pronuclear nuclear appearance abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001034
pronuclear nuclear appearance defective early emb
The morphology of pronuclei and nuclei are defective in the early embryo. In C. elegans, this defect is often characterized by pronuclei and nuclei that are small or missing altogether and are often accompanied by spindle defects.
WB:cab
WB:cgc7141
The size, number and organization of the components of the nuclei in the early embryo deviate from control . In C. elegans, this is characterized by nuclei that are completely missing or are significantly smaller than normal; often accompanied by spindle and cytokinesis defects.
Emb
nuclear appearance number abnormal
C_elegans_phenotype_ontology
nucleus abnormal emb
WBPhenotype:0001035
nuclear appearance number defective early emb
The size, number and organization of the components of the nuclei in the early embryo deviate from control . In C. elegans, this is characterized by nuclei that are completely missing or are significantly smaller than normal; often accompanied by spindle and cytokinesis defects.
WB:cab
WB:cgc7141
Any variation that compromises the reproductive ability of an F1 generation animal.
C_elegans_phenotype_ontology
WBPhenotype:0001036
sterile F1
Any variation that compromises the reproductive ability of an F1 generation animal.
WB:WBPerson2021
WB:WBPerson557
Any variation that compromises the reproductive ability of the progeny of an animal.
Stp
C_elegans_phenotype_ontology
WBPhenotype:0001037
sterile progeny
Any variation that compromises the reproductive ability of the progeny of an animal.
WB:WBPerson2021
WB:WBPerson557
Germ cells do not exit the mitotic cycle, resulting in a expansion of the unspecialized germ cell population compared to control.
Tum
tumorous germ line
C_elegans_phenotype_ontology
WBPhenotype:0001038
tumorous germline
Germ cells do not exit the mitotic cycle, resulting in a expansion of the unspecialized germ cell population compared to control.
WB:WBPaper00002730
WB:WBPerson2021
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the embryonic stage compared to control animals.
embryonic growth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001039
embryonic growth variant
Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the embryonic stage compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus, compared to control.
chemosensory response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001040
chemosensory response variant
Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus, compared to control.
GO:0042221
WB:WBPerson2021
WB:cab
WB:cgc3824
Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality.
Emb
Mei
C_elegans_phenotype_ontology
WBPhenotype:0001041
meiosis defective early emb
Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality.
WB:WBPerson2021
WB:WBPerson557
Neurons show impaired ability in the detection, transmission, coordination or their response to information about an animal's internal and external environments.
C_elegans_phenotype_ontology
WBPhenotype:0001042
neuron function reduced
Neurons show impaired ability in the detection, transmission, coordination or their response to information about an animal's internal and external environments.
WB:WBPerson2021
WB:WBPerson557
Embryos do not enter or take longer to enter first interphase compared to control.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001043
interphase entry defective early emb
Embryos do not enter or take longer to enter first interphase compared to control.
WB:cab
WB:cgc7141
Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage.
Cpa
Emb
cortical dynamics abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001044
cortical dynamics defective early emb
Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage.
WB:cab
WB:cgc7141
Pharyngeal pumping contractions are brief and occur arhythmically in response to stimulus compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001045
sporadic pumping
Pharyngeal pumping contractions are brief and occur arhythmically in response to stimulus compared to control.
WB:WBPaper00001709
Any variations associated with the characteristic morphology of the pharyngeal muscle such as shape, birefringence etc compared to control.
pharyngeal muscle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001046
pharyngeal muscle morphology variant
Any variations associated with the characteristic morphology of the pharyngeal muscle such as shape, birefringence etc compared to control.
WB:WBPaper00001709
Animals exhibit variations in the movement towards typically attractive water-soluble chemicals compared to control.
aqueous positive chemotaxis abnormal
C_elegans_phenotype_ontology
water soluble chemotaxis abnormal
WBPhenotype:0001047
aqueous positive chemotaxis variant
Animals exhibit variations in the movement towards typically attractive water-soluble chemicals compared to control.
WB:cab
WB:cgc3824
Animals exhibit variations in the chemosensory response to volatile organic compounds compared to control.
Odr
odorant chemosensory response abnormal
C_elegans_phenotype_ontology
volatile chemosensory response abnormal
WBPhenotype:0001048
odorant chemosensory response variant
Animals exhibit variations in the chemosensory response to volatile organic compounds compared to control.
WB:WBPerson2021
Variations in behavior that is dependent upon the sensation of chemicals, compared to control.
chemosensory behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001049
chemosensory behavior variant
Variations in behavior that is dependent upon the sensation of chemicals, compared to control.
GO:0007635
WB:WBPerson2021
Animals exhibit variations in any of a series of events in which an organism receives a sensory chemical stimulus, converts it to a molecular signal, and recognizes and characterizes the signal, compared to control.
chemosensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001050
chemosensation variant
Animals exhibit variations in any of a series of events in which an organism receives a sensory chemical stimulus, converts it to a molecular signal, and recognizes and characterizes the signal, compared to control.
GO:0007606
WB:WBPerson2021
Animals exhibit variations in the characteristic movement towards typically attractive cations compared to control.
cation positive chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001051
cation positive chemotaxis variant
Animals exhibit variations in the characteristic movement towards typically attractive cations compared to control.
WB:WBPaper00000387
WB:cab
WB:cgc387
Animals exhibit variations in the characteristic movement towards typically attractive anions compared to control.
anion positive chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001052
anion positive chemotaxis variant
Animals exhibit variations in the characteristic movement towards typically attractive anions compared to control.
WB:WBPaper00000387
WB:cab
WB:cgc387
Animals exhibit variations in the characteristic movement towards cyclic nucleotides compared to control.
cyclic nucleotide positive chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001053
cyclic nucleotide positive chemotaxis variant
Animals exhibit variations in the characteristic movement towards cyclic nucleotides compared to control.
WB:cab
WB:cgc387
Animals fail to exhibit the same taxis behavior as control animals in response to cGMP. In C. elegans, this is characterized by the failure to move towards cGMP.
C_elegans_phenotype_ontology
WBPhenotype:0001054
cGMP chemotaxis defective
Animals fail to exhibit the same taxis behavior as control animals in response to cGMP. In C. elegans, this is characterized by the failure to move towards cGMP.
WB:WBPerson2021
WB:cab
WB:cgc387
Animals fail to exhibit the same taxis behavior as control animals in response to bromide. In C. elegans, this is characterized by the failure to move towards bromide.
C_elegans_phenotype_ontology
WBPhenotype:0001055
bromide chemotaxis defective
Animals fail to exhibit the same taxis behavior as control animals in response to bromide. In C. elegans, this is characterized by the failure to move towards bromide.
WB:cab
WB:cgc387
Animals fail to exhibit the same taxis behavior as control animals in response to iodide. In C. elegans, this is characterized by the failure to move towards iodide.
C_elegans_phenotype_ontology
WBPhenotype:0001056
iodide chemotaxis defective
Animals fail to exhibit the same taxis behavior as control animals in response to iodide. In C. elegans, this is characterized by the failure to move towards iodide.
WB:cab
WB:cgc387
Animals fail to exhibit the same taxis behavior as control animals in response to lithium. In C. elegans, this is characterized by the failure to move towards lithium.
C_elegans_phenotype_ontology
WBPhenotype:0001057
lithium chemotaxis defective
Animals fail to exhibit the same taxis behavior as control animals in response to lithium. In C. elegans, this is characterized by the failure to move towards lithium.
WB:cab
WB:cgc387
Animals fail to exhibit the same taxis behavior as control animals in response to potassium. In C. elegans, this is characterized by the failure of the animals to move towards potassium.
C_elegans_phenotype_ontology
WBPhenotype:0001058
potassium chemotaxis defective
Animals fail to exhibit the same taxis behavior as control animals in response to potassium. In C. elegans, this is characterized by the failure of the animals to move towards potassium.
WB:cab
WB:cgc387
Animals fail to exhibit the same taxis behavior as control animals in response to magnesium. In C. elegans, this is characterized by the failure to move towards magnesium.
C_elegans_phenotype_ontology
WBPhenotype:0001059
magnesium chemotaxis defective
Animals fail to exhibit the same taxis behavior as control animals in response to magnesium. In C. elegans, this is characterized by the failure to move towards magnesium.
WB:cab
WB:cgc387
In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWC compared to control.
C_elegans_phenotype_ontology
AWC volatile chemotaxis defective
WBPhenotype:0001060
AWC odorant chemotaxis defective
In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWC compared to control.
WB:WBPerson2021
In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWA compared to control.
C_elegans_phenotype_ontology
AWA volatile chemotaxis defective
WBPhenotype:0001061
AWA odorant chemotaxis defective
In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWA compared to control.
WB:WBPerson2021
In C. elegans, movement and elongation stop nearly simultaneously soon after the twofold stage of elongation. However, mutant embryos twitch at the one-and-a-half-fold stage of elongation, like control animals, and move as well as control animals at the two- fold stage.
C_elegans_phenotype_ontology
WBPhenotype:0001062
late paralysis arrested elongation two fold
In C. elegans, movement and elongation stop nearly simultaneously soon after the twofold stage of elongation. However, mutant embryos twitch at the one-and-a-half-fold stage of elongation, like control animals, and move as well as control animals at the two- fold stage.
WB:cab
WB:cgc1894
Fluctuation pattern between inactive, active, and egg-laying states is atypical, based on the analysis of the distribution of the log intervals of egg-laying events compared to control.
egg laying phases abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001063
egg laying phases variant
Fluctuation pattern between inactive, active, and egg-laying states is atypical, based on the analysis of the distribution of the log intervals of egg-laying events compared to control.
WB:cab
pmid:10757762
pmid:9697864
Animals display uncharacteristically long periods during which they do not lay eggs compared to control, usually based on the analysis of the distribution of the log intervals of egg-laying events. In C. elegans, long inactive phases can be observed in HSN-ablated and serotonin-deficient animals.
C_elegans_phenotype_ontology
WBPhenotype:0001064
inactive phase long
Animals display uncharacteristically long periods during which they do not lay eggs compared to control, usually based on the analysis of the distribution of the log intervals of egg-laying events. In C. elegans, long inactive phases can be observed in HSN-ablated and serotonin-deficient animals.
WB:cab
pmid:10757762
pmid:9697864
Fewer egg-laying events occur within the active phase of egg laying, based on the analysis of the distribution of the log intervals of egg-laying events, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001065
fewer egg laying events during active
Fewer egg-laying events occur within the active phase of egg laying, based on the analysis of the distribution of the log intervals of egg-laying events, compared to control.
WB:cab
pmid:9697864
The period during which the animal is less likely to lay eggs is not typical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
inactive phase abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001066
inactive phase variant
The period during which the animal is less likely to lay eggs is not typical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
pmid:10757762
pmid:9697864
The active phase of egg-laying, the period during which animals are more likely to display multiple egg-laying events, is atypical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
active phase abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001067
active phase variant
The active phase of egg-laying, the period during which animals are more likely to display multiple egg-laying events, is atypical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
pmid:9697864
Animals are not induced to lay eggs in reponse to exogenous serotonin. Serotonin stimulates egg-laying in C. elegans.
C_elegans_phenotype_ontology
WBPhenotype:0001068
egg laying serotonin resistant
Animals are not induced to lay eggs in reponse to exogenous serotonin. Serotonin stimulates egg-laying in C. elegans.
WB:WBPaper00000635
WB:WBPaper00031293
WB:WBPerson712
More eggs are laid during the active phase compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
C_elegans_phenotype_ontology
WBPhenotype:0001069
increased egg laying events during active
More eggs are laid during the active phase compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
pmid:9697864
The period during which a worm usually does not lay eggs is short compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
C_elegans_phenotype_ontology
WBPhenotype:0001070
inactive phase short
The period during which a worm usually does not lay eggs is short compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
pmid:9697864
Activation of the active phase of egg laying is defective, leading to an abnormally long inactive phase, based on the analysis of the distribution of the log intervals of egg-laying events.
C_elegans_phenotype_ontology
WBPhenotype:0001071
active phase switch defective
Activation of the active phase of egg laying is defective, leading to an abnormally long inactive phase, based on the analysis of the distribution of the log intervals of egg-laying events.
WB:cab
pmid:10757762
pmid:9697864
Any variation in the state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to a food stimulus, compared to control.
response to food abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001072
response to food variant
Any variation in the state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to a food stimulus, compared to control.
GO:0032094
WB:WBPerson2021
Animals exhibit variations in egg-laying behavior in response to food compared to control. In C. elegans, well-fed animals lay more eggs compared with starved animals.
egg laying response to food abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001073
egg laying response to food variant
Animals exhibit variations in egg-laying behavior in response to food compared to control. In C. elegans, well-fed animals lay more eggs compared with starved animals.
WB:cab
pmid:10757762
The vulval muscle does not respond to serotonin in the same manner as control animals. This phenotype is often assayed by imaging of calcium transients in response to serotonin.
C_elegans_phenotype_ontology
WBPhenotype:0001074
vulval muscle unresponsive to serotonin
The vulval muscle does not respond to serotonin in the same manner as control animals. This phenotype is often assayed by imaging of calcium transients in response to serotonin.
WB:cab
pmid:14588249
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the vulva muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
vulval muscle physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001075
vulval muscle physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the vulva muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Variations in the chemical reactions and pathways involved in the maintenance of an internal equilibrium within the vulval muscles compared to control.
vulval muscle homeostasis metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001076
vulval muscle homeostasis metabolism variant
Variations in the chemical reactions and pathways involved in the maintenance of an internal equilibrium within the vulval muscles compared to control.
WB:WBPerson2021
WB:WBPerson557
Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001077
chromosome segregation variant karyomeres early emb
Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle.
WB:cab
WB:cgc7141
Cytokinesis is abnormal in the first or second stages of cell division.
Cyk
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001078
cytokinesis defective early emb
Cytokinesis is abnormal in the first or second stages of cell division.
WB:cab
WB:cgc7141
Cytoplasmic movements are atypical.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001079
cytoplasmic dynamics defective early emb
Cytoplasmic movements are atypical.
WB:WBPerson1815
WB:cab
Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001080
excessive blebbing early emb
Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
WB:cab
cgc:5599
Morphology of the cytoplasm differs from control animals.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001081
cytoplasmic morphology defective early emb
Morphology of the cytoplasm differs from control animals.
WB:WBPerson1815
WB:cab
Abnormally large granules are observed in the cytoplasm of P0.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001082
large cytoplasmic granules early emb
Abnormally large granules are observed in the cytoplasm of P0.
WB:cab
WB:cgc5599
Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001083
multiple cytoplasmic cavities early emb
Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis.
WB:cab
cgc:5599
Failure to execute characteristic response to sodium chloride compared to control. In C. elegans, animals move towards attractive concentrations of sodium chloride.
NaCl chemotaxis defective
C_elegans_phenotype_ontology
WBPhenotype:0001084
sodium chloride chemotaxis defective
Failure to execute characteristic response to sodium chloride compared to control. In C. elegans, animals move towards attractive concentrations of sodium chloride.
WB:WBPaper00000119
Failure to execute characteristic response to butanone compared to control. In C. elegans, animals move towards typically attractive concentrations of butanone.
C_elegans_phenotype_ontology
WBPhenotype:0001085
butanone chemotaxis defective
Failure to execute characteristic response to butanone compared to control. In C. elegans, animals move towards typically attractive concentrations of butanone.
WB:WBPaper00001786
Failure to execute characteristic response to trimethylthiazole compared to control. In C. elegans, animals move towards typically attractive concentrations of trimethylthiazole.
C_elegans_phenotype_ontology
WBPhenotype:0001086
trimethylthiazole chemotaxis defective
Failure to execute characteristic response to trimethylthiazole compared to control. In C. elegans, animals move towards typically attractive concentrations of trimethylthiazole.
WB:WBPaper00001786
Failure to execute characteristic response to acetone compared to control. In C. elegans, animals move towards typically attractive concentrations of acetone.
C_elegans_phenotype_ontology
WBPhenotype:0001087
acetone chemotaxis defective
Failure to execute characteristic response to acetone compared to control. In C. elegans, animals move towards typically attractive concentrations of acetone.
WB:WBPaper00024240
Failure to execute characteristic response to pentanol compared to control. In C. elegans, animals move towards typically attractive concentrations of pentanol.
C_elegans_phenotype_ontology
WBPhenotype:0001088
pentanol chemotaxis defective
Failure to execute characteristic response to pentanol compared to control. In C. elegans, animals move towards typically attractive concentrations of pentanol.
WB:WBPerson2021
Failure to execute characteristic response to hexanol compared to control. In C. elegans, animals move towards typically attractive concentrations of hexanol.
C_elegans_phenotype_ontology
WBPhenotype:0001089
hexanol chemotaxis defective
Failure to execute characteristic response to hexanol compared to control. In C. elegans, animals move towards typically attractive concentrations of hexanol.
WB:WBPerson2021
Animals are not able to survive at temperatures above standard cultivation temperatures to the same extent as control animals.
intrinsic thermotolerance reduced
C_elegans_phenotype_ontology
WBPhenotype:0001090
thermotolerance reduced
Animals are not able to survive at temperatures above standard cultivation temperatures to the same extent as control animals.
WB:WBPerson712
Animals exhibit variations in the elimination of fecal matter during the larval stage compared to control animals.
larval defecation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001091
larval defecation variant
Animals exhibit variations in the elimination of fecal matter during the larval stage compared to control animals.
WB:WBPerson2021
Animals fail to expel fecal matter during the larval stage.
C_elegans_phenotype_ontology
WBPhenotype:0001092
larval defecation defect
Animals fail to expel fecal matter during the larval stage.
WB:WBPerson2021
Animals exhibit variations in any physical or chemical process required for the intestine to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
intestinal physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001093
intestinal physiology variant
Animals exhibit variations in any physical or chemical process required for the intestine to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
OBSOLETE. Organismal response to NaCl differs from control animals.
NaCl response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001094
obsolete NaCl response variant
true
OBSOLETE. Organismal response to NaCl differs from control animals.
WB:cab
Animals respond to sodium chloride at a lower concentration or a shorter exposure compared to control animals. In C. elegans, this is often assayed through generation time and progeny number.
C_elegans_phenotype_ontology
WBPhenotype:0001095
organism high sodium chloride hypersensitive
Animals respond to sodium chloride at a lower concentration or a shorter exposure compared to control animals. In C. elegans, this is often assayed through generation time and progeny number.
WB:cab
pmid:16027367
Large protrusion at the normal position of the vulva, as seen in C. elegans lin-12 null animals.
ventral protrusion
C_elegans_phenotype_ontology
WBPhenotype:0001096
protrusion at vulval region
Large protrusion at the normal position of the vulva, as seen in C. elegans lin-12 null animals.
WB:cab
cgc:646
Unspecialized male germ cells (spermatocytes) prematurely acquire the specialized properties of functional sperm.
C_elegans_phenotype_ontology
WBPhenotype:0001097
premature spermatocyte germ cell differentiation
Unspecialized male germ cells (spermatocytes) prematurely acquire the specialized properties of functional sperm.
WB:WBPerson2021
WB:cab
cgc:4207
Animals lack the passage connecting the posterior intestine to the rectal valve.
C_elegans_phenotype_ontology
WBPhenotype:0001098
WBbt:0005773.
no rectum
Animals lack the passage connecting the posterior intestine to the rectal valve.
WB:WBPaper00001423
WB:WBPerson2021
The extreme anterior part of the body appears distorted, usually due to uncharacteristic winding.
C_elegans_phenotype_ontology
WBPhenotype:0001099
nose twisted
The extreme anterior part of the body appears distorted, usually due to uncharacteristic winding.
WB:WBPerson2021
WB:WBPerson557
Animal dies prior to the gastrulation stage of embryogenesis.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001100
early embryonic lethal
Animal dies prior to the gastrulation stage of embryogenesis.
WB:WBPerson2021
Characteristic response to drugs with respect to egg-laying behavior varies compared to control.
egg laying response to drug abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001101
egg laying response to drug variant
Characteristic response to drugs with respect to egg-laying behavior varies compared to control.
WB:cab
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001102
Possible XP.
mitotic spindle defective early emb
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle.
GO:0007052
WB:WBPerson2021
Early embryos lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001103
spindle absent early emb
Early embryos lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
GO:0005819
WB:WBPerson2021
No mitotic spindle is seen in P0.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001104
P0 spindle absent early emb
No mitotic spindle is seen in P0.
WB:cab
WB:cgc5599
Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal.
Emb
P0 spindle position phenotype
C_elegans_phenotype_ontology
WBPhenotype:0001105
P0 spindle position abnormal
Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal.
WB:cab
WB:cgc5599
The orientation of the spindle is aberrant in either the AB or the P1 cell.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001106
spindle orientation variant AB or P1 early emb
The orientation of the spindle is aberrant in either the AB or the P1 cell.
WB:cab
WB:cgc5599
Rotation of the embryonic spindle is aberrant.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001107
spindle rotation defective early emb
Rotation of the embryonic spindle is aberrant.
WB:WBPerson1815
WB:cab
P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001108
P0 spindle rotation failure early emb
P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo.
WB:cab
WB:cgc5599
P0 spindle rotates late in the inviable one- to four-cell embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001109
P0 spindle rotation delayed early emb
P0 spindle rotates late in the inviable one- to four-cell embryo.
WB:cab
WB:cgc5599
Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores.
Emb
aster abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001110
aster defective early emb
Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores.
GO:0005818
WB:WBPerson2021
WB:WBPerson557
Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the AB cell.
Emb
aster AB abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001111
aster AB defective early emb
Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the AB cell.
WB:WBPerson2021
WB:WBPerson557
The morphology of the AB aster resembles that of the P1 aster in the inviable one- to four-cell embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001112
aster AB resembles P1 aster early emb
The morphology of the AB aster resembles that of the P1 aster in the inviable one- to four-cell embryo.
WB:cab
WB:cgc5599
Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell.
Emb
P1 aster abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001113
P1 aster defective early emb
Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell.
WB:WBPerson2021
WB:WBPerson557
WB:cab
WB:cgc5599
The progression of biochemical and morphological processes that occur during successive replication or nuclear replication events is disrupted during the early embryonic stage.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001114
cell cycle defective early emb
The progression of biochemical and morphological processes that occur during successive replication or nuclear replication events is disrupted during the early embryonic stage.
WB:WBPerson2021
WB:WBPerson557
Cell cycle timing is abnormal during the first four cell divisions.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001115
cell cycle timing defective early emb
Cell cycle timing is abnormal during the first four cell divisions.
WB:WBPerson1815
WB:cab
Absolute cell cycle timing during the first four cell divisions is aberrant.
Emb
absolute cell cycle timing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001116
absolute cell cycle timing defective early emb
Absolute cell cycle timing during the first four cell divisions is aberrant.
WB:WBPerson557
Cell-cell contacts are abnormal in the early embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001117
cell cell contacts abnormal early emb
Cell-cell contacts are abnormal in the early embryo.
WB:WBPerson1815
WB:cab
Cell position is abnormal in the early embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001118
cell position defective early emb
Cell position is abnormal in the early embryo.
WB:WBPerson1815
WB:cab
Embryos take longer to divide during the first and second cell divisions.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001119
cell cycle slow early emb
Embryos take longer to divide during the first and second cell divisions.
WB:cab
WB:cgc5599
Relative cell cycle timing during the first four cell divisions is aberrant.
Emb
relative cell cycle timing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001120
relative cell cycle timing defective early emb
Relative cell cycle timing during the first four cell divisions is aberrant.
WB:WBPerson1815
WB:cab
Asynchrony of the second division is exaggerated and P1 divides more slowly than normal.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001121
exaggerated asynchrony early emb
Asynchrony of the second division is exaggerated and P1 divides more slowly than normal.
WB:cab
WB:cgc5599
P1 divides before AB.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001122
reversed asynchrony early emb
P1 divides before AB.
WB:cab
WB:cgc5599
AB and P1 divide synchronously.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001123
synchronous second division early emb
AB and P1 divide synchronously.
WB:cab
WB:cgc5599
EMS divides at the same time that ABa and ABp divide.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001124
ABa ABp EMS synchronous division early emb
EMS divides at the same time that ABa and ABp divide.
WB:cab
WB:cgc5599
P2 and EMS divide synchronously.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001125
P2 EMS synchronous division early emb
P2 and EMS divide synchronously.
WB:cab
WB:cgc5599
Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos.
Emb
cell cell contacts abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001126
cell cell contacts abnormal in four cell embryo
Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos.
WB:cab
WB:cgc5599
The EMS blastomere fails to extend anteriorly and make extensive contact (hug) with the ABa blastomere.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001127
EMS anterior extension fails early emb
The EMS blastomere fails to extend anteriorly and make extensive contact (hug) with the ABa blastomere.
WB:cab
WB:cgc5599
EMS extends too far anteriorly at the four cell stage.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001128
EMS anterior extension extreme early emb
EMS extends too far anteriorly at the four cell stage.
WB:cab
WB:cgc5599
Embryos exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001129
cleavage furrow defective early emb
Embryos exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
GO:0032154
WB:WBPerson2021
WB:WBPerson2987
WB:WBPerson557
Cells of the embryo attempt to divide but fail to form two daughter cells.
Cyk
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001130
cytokinesis fails early emb
Cells of the embryo attempt to divide but fail to form two daughter cells.
WB:cab
WB:cgc5599
Once formed, the mitotic furrow can "slide"laterally.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001131
loose mitotic furrow early emb
Once formed, the mitotic furrow can "slide"laterally.
WB:cab
WB:cgc5599
One or more extra cleavage furrows are seen in one or more cells of a one-cell to four-cell embryo
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001132
extra cleavage furrow early emb
One or more extra cleavage furrows are seen in one or more cells of a one-cell to four-cell embryo
WB:cab
WB:cgc5599
The cell division axis is not normal.
division axis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001133
division axis defective
The cell division axis is not normal.
WB:WBPerson1815
WB:cab
ABa or ABp divide in the wrong orientation.
Emb
Aba ABp division axis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001134
Aba ABp division axis defective early emb
ABa or ABp divide in the wrong orientation.
WB:cab
WB:cgc5599
Animals exhibit defects in the form, structure or composition of any of its parts during the early embryonic stage.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001135
embryonic morphology defective early emb
Animals exhibit defects in the form, structure or composition of any of its parts during the early embryonic stage.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control.
embryonic morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001136
embryonic morphology variant
Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control.
WB:WBPerson2021
WB:WBPerson557
Embryos are produced that are less than fifty percent of the size of control embryos.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001137
embryos small early emb
Embryos are produced that are less than fifty percent of the size of control embryos.
WB:WBPaper00005599
WB:cab
Nucleus is abnormal in the inviable one- to four-cell embryo.
Emb
nucleus abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001138
nucleus defective early emb
Nucleus is abnormal in the inviable one- to four-cell embryo.
WB:WBPerson1815
WB:cab
Nuclear envelope does not reassemble properly.
Emb
C_elegans_phenotype_ontology
nuclear reassembly defective early emb
WBPhenotype:0001139
nuclear envelope assembly variant early emb
Nuclear envelope does not reassemble properly.
WB:cab
WB:cgc5599
Any variation in the normal orderly movement of neurons from one site to another compared to control.
neuron migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001140
neuron migration variant
Any variation in the normal orderly movement of neurons from one site to another compared to control.
WB:WBPerson2021
After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001141
nucleus reforms cell division remnant early emb
After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant.
WB:cab
WB:cgc5599
Nuclear number is abnormal in the inviable one- to four-cell embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001142
nuclear number defective early emb
Nuclear number is abnormal in the inviable one- to four-cell embryo.
WB:WBPerson1815
WB:cab
Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
Emb
Mul
C_elegans_phenotype_ontology
karyomeres
multiple nuclei in early embryo emb
WBPhenotype:0001143
multiple nuclei early emb
Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WB:cab
WB:cgc5599
Defects are either seen in the number or size of the polar bodies in the inviable one- to four-cell embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001144
polar body number size early emb
Defects are either seen in the number or size of the polar bodies in the inviable one- to four-cell embryo.
WB:cab
WB:cgc5599
Polar body number is abnormal in the inviable one- to four-cell embryo.
Emb
polar body number abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001145
polar body number defective early emb
Polar body number is abnormal in the inviable one- to four-cell embryo.
WB:WBPerson1815
WB:cab
Polar body size is abnormal in the inviable one- to four-cell embryo.
Emb
polar body size abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001146
polar body size defective early emb
Polar body size is abnormal in the inviable one- to four-cell embryo.
WB:WBPerson1815
WB:cab
Polar bodies are abnormal in the inviable one- to four-cell embryo.
Emb
polar body abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001147
polar body defective early emb
Polar bodies are abnormal in the inviable one- to four-cell embryo.
WB:WBPerson1815
WB:cab
Polar body is reabsorbed in the one- to four-cell embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001148
polar body reabsorbed early emb
Polar body is reabsorbed in the one- to four-cell embryo.
WB:WBPerson1815
WB:cab
OBSOLETE.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001149
obsolete polar body reabsorbed first early emb
true
OBSOLETE.
WB:WBPerson557
A polar body is reabsorbed in either the one cell- or the two-cell embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001150
polar body reabsorbed one two early emb
A polar body is reabsorbed in either the one cell- or the two-cell embryo.
WB:cab
WB:cgc5599
Pronucleus is abnormal in the inviable embryo.
Emb
pronucleus centrosomes abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001151
pronucleus centrosomes defective early emb
Pronucleus is abnormal in the inviable embryo.
WB:WBPerson1815
WB:cab
Pronucleus migration is abnormal in the inviable embryo.
Emb
pronuclear migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001152
pronuclear migration defective early emb
Pronucleus migration is abnormal in the inviable embryo.
WB:WBPerson1815
WB:cab
Neither of the pronuclei migrate and they never meet.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001153
pronuclear migration failure early emb
Neither of the pronuclei migrate and they never meet.
WB:cab
WB:cgc5599
Instead of the maternal pronucleus migrating to the posterior end of the one-cell embryo, the paternal pronucleus migrates to meet the maternal pronucleus in the anterior end.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001154
paternal pronucleus migrates early emb
Instead of the maternal pronucleus migrating to the posterior end of the one-cell embryo, the paternal pronucleus migrates to meet the maternal pronucleus in the anterior end.
WB:cab
WB:cgc5599
The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001155
pronuclei meet centrally early emb
The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WB:cab
WB:cgc5599
Maternal or paternal pronucleus is either too small or too large.
Emb
pronuclear size abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001156
pronuclear size defective early emb
Maternal or paternal pronucleus is either too small or too large.
WB:cab
WB:cgc5599
Pronuclear breakdown is atypical in the inviable embryo.
Emb
pronuclear breakdown abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001157
pronuclear breakdown defective early emb
Pronuclear breakdown is atypical in the inviable embryo.
WB:WBPerson1815
WB:cab
Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001158
pronuclear breakdown asynchronous early emb
Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo.
WB:cab
WB:cgc5599
Pronucleus morphology is atypical in the inviable embryo.
Emb
pronuclear morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001159
pronuclear morphology defective early emb
Pronucleus morphology is atypical in the inviable embryo.
WB:cab
WB:cgc5599
Morphology of the pronuclear envelope is atypical in the inviable embryo.
Emb
pronuclear envelope morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001160
pronuclear envelope morphology defective early emb
Morphology of the pronuclear envelope is atypical in the inviable embryo.
WB:WBPerson1815
WB:cab
Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001161
maternal pronucleus indistinct early emb
Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape.
WB:cab
WB:cgc5599
There are more than two pronuclei in the inviable embryo.
Emb
pronuclear number abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001162
pronuclear number defective early emb
There are more than two pronuclei in the inviable embryo.
WB:WBPerson1815
WB:cab
Either the maternal or paternal pronucleus is absent.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001163
pronucleus formation failure early emb
Either the maternal or paternal pronucleus is absent.
WB:cab
WB:cgc5599
There is either more than one maternal or paternal pronucleus in the inviable embryo.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001164
excess pronucleus early emb
There is either more than one maternal or paternal pronucleus in the inviable embryo.
WB:WBPerson1815
WB:cab
One-cell embryos have two or more maternal pronuclei.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001165
excess maternal pronucleus early emb
One-cell embryos have two or more maternal pronuclei.
WB:cab
WB:cgc5599
More than one paternal pronucleus is present in the inviable one-cell embryo or there is a defect in centrosome structure.
Emb
excess paternal pronucleus abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001166
excess paternal pronucleus variant centrosome early emb
More than one paternal pronucleus is present in the inviable one-cell embryo or there is a defect in centrosome structure.
WB:cab
WB:cgc5599
Pseudocleavage is atypical in the inviable one-cell embryo.
Emb
pseudocleavage abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001167
pseudocleavage defective early emb
Pseudocleavage is atypical in the inviable one-cell embryo.
WB:WBPerson1815
WB:cab
No pseudocleavage is observed before or during pronuclear migration.
Emb
C_elegans_phenotype_ontology
no pseudocleavage
WBPhenotype:0001168
pseudocleavage absent early emb
No pseudocleavage is observed before or during pronuclear migration.
WB:cab
WB:cgc5599
Embryos have more pronounced pseudocleavage than normal.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001169
pseudocleavage exaggerated early emb
Embryos have more pronounced pseudocleavage than normal.
WB:cab
WB:cgc5599
Injected worm stops producing embryos 48 hours after RNAi injection and contains no live/developing embryos at this time.
Ste
P0 sterile
C_elegans_phenotype_ontology
WBPhenotype:0001170
sterile F0 48 hours post injection
Injected worm stops producing embryos 48 hours after RNAi injection and contains no live/developing embryos at this time.
WB:cab
WB:cgc5599
The duration of viability in the adult phase of the life-cycle is less than that of control animals.
Age
C_elegans_phenotype_ontology
life span reduced
longevity decreased
WBPhenotype:0001171
shortened life span
The duration of viability in the adult phase of the life-cycle is less than that of control animals.
GO:0008340
WB:WBPerson712
Developmentally regulated termination of a cell or cell group does not occur as in control animals.
programmed cell death abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001172
programmed cell death variant
Developmentally regulated termination of a cell or cell group does not occur as in control animals.
WB:WBPerson712
Animals exhibit variations in the specific activation or halting of processes within a cell that occur through necrosis or programmed cell death pathways different from apoptosis, so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death, compared to control.
non apoptotic cell death abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001173
non apoptotic cell death variant
Animals exhibit variations in the specific activation or halting of processes within a cell that occur through necrosis or programmed cell death pathways different from apoptosis, so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death, compared to control.
GO:0008219
WB:WBPerson712
Chromosomes fail to segregate away from their homolog, resulting in gametes with no or extra copies of the chromosome.
chromosome disjunction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001174
chromosome disjunction defective
Chromosomes fail to segregate away from their homolog, resulting in gametes with no or extra copies of the chromosome.
WB:WBPerson712
Higher numbers of male progeny occur in the population compared to control populations. In C. elegans, the high incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an increase in X chromosome nondisjunction.
Him
C_elegans_phenotype_ontology
high frequency X chromosome nondisjunction
WBPhenotype:0001175
high incidence male progeny
Higher numbers of male progeny occur in the population compared to control populations. In C. elegans, the high incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an increase in X chromosome nondisjunction.
WB:WBPaper00004402
WB:WBPaper00005654
WB:WBPerson712
WB:cab
One-cell embryos have an altered shape.
Emb
one cell shape abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001176
one cell shape defective early emb
One-cell embryos have an altered shape.
WB:cab
WB:cgc5599
Embryos rupture when placed on a 2% agar pad and covered with a coverslip.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001177
embryo osmotic pressure sensitive early emb
Embryos rupture when placed on a 2% agar pad and covered with a coverslip.
WB:cab
WB:cgc5599
The structure of the egg is impaired, flawed or no longer intact.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001178
egg integrity defective early emb
The structure of the egg is impaired, flawed or no longer intact.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE. Phenotypic examination of worms did not reveal an obvious abnormality compared with control animals.
No abnormal
C_elegans_phenotype_ontology
WT
WBPhenotype:0001179
The phenotype ontology was restructured such that "Abnormal" is now the root term. The term "Abnormal" with a "Not" qualifier is a suggested replacement for this term.
This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype.
obsolete No variantity scored
true
OBSOLETE. Phenotypic examination of worms did not reveal an obvious abnormality compared with control animals.
WB:cab
Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
C_elegans_phenotype_ontology
WBPhenotype:0001180
accumulated germline cell corpses
Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
WB:WBPerson712
Animals exhibit an increase in the quantity of non-germ line cells that have undergone programmed cell death but have not been engulfed.
C_elegans_phenotype_ontology
WBPhenotype:0001181
accumulated somatic cell corpses
Animals exhibit an increase in the quantity of non-germ line cells that have undergone programmed cell death but have not been engulfed.
WB:WBPerson712
Animals exhibit variations in the amount of fat or lipids present in the organism compared to control animals.
fat content abnormal
C_elegans_phenotype_ontology
lipid content abnormal
lipid content variant
WBPhenotype:0001182
fat content variant
Animals exhibit variations in the amount of fat or lipids present in the organism compared to control animals.
GO:0019915
WB:WBPaper00032082
WB:WBPerson712
Animals exhibit less fat or lipid than observed in control animals.
C_elegans_phenotype_ontology
lipid content reduced
WBPhenotype:0001183
fat content reduced
Animals exhibit less fat or lipid than observed in control animals.
GO:0019915
WB:WBPaper00032082
WB:WBPerson712
Animals exhibit a greater amount of fat or lipids than observed in control animals.
C_elegans_phenotype_ontology
lipid content increased
WBPhenotype:0001184
fat content increased
Animals exhibit a greater amount of fat or lipids than observed in control animals.
GO:0019915
WB:WBPaper00032082
WB:WBPerson712
The developmental progression of an early embryo over time, from its formation to its mature structure is delayed compared to control.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001185
embryonic developmental delay early emb
The developmental progression of an early embryo over time, from its formation to its mature structure is delayed compared to control.
WB:WBPerson2021
WB:WBPerson557
Embryos are either delayed or arrested at pronuclear contact.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001186
embryo delayed at pronuclear contact early emb
Embryos are either delayed or arrested at pronuclear contact.
WB:cab
WB:cgc5599
EMS divides before P2.
Emb
C_elegans_phenotype_ontology
WBPhenotype:0001187
division EMS before P2 early emb
EMS divides before P2.
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of radial arrangement of actin within the pharyngeal muscle compared to control animals.
radial filament structure abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001188
radial filament structure variant pharynx
Animals exhibit variations in the form, structure or composition of radial arrangement of actin within the pharyngeal muscle compared to control animals.
WB:WBPaper00026850
WB:WBPerson2021
WB:WBPerson557
Any variation in the cell junctions of the pharyngeal muscle at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control.
adherens junctions abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001189
adherens junctions variant pharyngeal muscle
Any variation in the cell junctions of the pharyngeal muscle at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control.
WB:WBPaper00026850
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for the pharynx to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
pharyngeal physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001190
pharyngeal physiology variant
Animals exhibit variations in any physical or chemical process required for the pharynx to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for muscles in the pharynx to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
pharyngeal muscle physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001191
pharyngeal muscle physiology variant
Animals exhibit variations in any physical or chemical process required for muscles in the pharynx to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Any variation in the series of molecular signals in which a pharyngeal cell uses calcium ions to convert an extracellular signal into a response, compared to control.
calcium signaling pharynx abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001192
calcium signaling in pharynx variant
Any variation in the series of molecular signals in which a pharyngeal cell uses calcium ions to convert an extracellular signal into a response, compared to control.
WB:WBPerson2021
WB:WBPerson557
Electropharyngeograms do not show a similar pattern as control animals. C. elegans animals show a repeating regular pattern in which each pump is associated with an excitatory depolarizing wave, often punctuated by brief negative spikes, followed by a plateau phase, and ending with an inhibitory hyperpolarizing wave.
C_elegans_phenotype_ontology
WBPhenotype:0001193
disorganized pharyngeal EPG
Electropharyngeograms do not show a similar pattern as control animals. C. elegans animals show a repeating regular pattern in which each pump is associated with an excitatory depolarizing wave, often punctuated by brief negative spikes, followed by a plateau phase, and ending with an inhibitory hyperpolarizing wave.
WB:cab
WB:cgc7545
Animals have one or more extra neurons, which are present in places they are normally not found, when compared to the number and location of these neurons in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001194
extra and ectopic neuron
Animals have one or more extra neurons, which are present in places they are normally not found, when compared to the number and location of these neurons in control animals.
WB:WBPaper00027335
WB:WBPerson712
Rhythmic calcium increases in the pharynx are observed less often than in control animals. In C. elegans, rhythmic increases in intracellular calcium are often observed using a transgenically expressed cameleon, a ratiometric calcium indicator.
C_elegans_phenotype_ontology
WBPhenotype:0001195
generation calcium signal defective pharynx
Rhythmic calcium increases in the pharynx are observed less often than in control animals. In C. elegans, rhythmic increases in intracellular calcium are often observed using a transgenically expressed cameleon, a ratiometric calcium indicator.
WB:cab
WB:cgc4194
WB:cgc7545
Calcium spikes lack synchrony in the musculature of the corpus and the terminal bulb as seen in control.
C_elegans_phenotype_ontology
WBPhenotype:0001196
synchronization calcium signal defective pharynx
Calcium spikes lack synchrony in the musculature of the corpus and the terminal bulb as seen in control.
WB:cab
WB:cgc7545
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic gonad to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
somatic gonad physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001197
somatic gonad physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic gonad to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic sheath system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
somatic sheath physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001198
somatic sheath physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic sheath system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the contraction of a thin continuous tube surrounding the proximal portions of the ovary and covering the maturing oocytes to the near portion of the distal gonad arm, compared to control (Wormatlas).
gonad sheath contractions abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001199
gonad sheath contractions variant
Animals exhibit variations in any physical or chemical process required for the contraction of a thin continuous tube surrounding the proximal portions of the ovary and covering the maturing oocytes to the near portion of the distal gonad arm, compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Basal contraction rate and or peak contraction rate of the gonadal sheath is reduced relative to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001200
gonad sheath contraction rate reduced
Basal contraction rate and or peak contraction rate of the gonadal sheath is reduced relative to control animals.
WB:cab
WB:cgc7545
Animals lack the stereotyped muscle contractions that result in the opening of anus.
C_elegans_phenotype_ontology
WBPhenotype:0001201
no expulsion defecation
Animals lack the stereotyped muscle contractions that result in the opening of anus.
WB:WBPerson2021
WB:WBPerson557
Animals respond to nicotine at lower concentrations or shorter exposure compared to control. Nicotine is a cholinergic agonist.
C_elegans_phenotype_ontology
WBPhenotype:0001202
nicotine hypersensitive
Animals respond to nicotine at lower concentrations or shorter exposure compared to control. Nicotine is a cholinergic agonist.
WB:WBPerson557
WB:cab
WB:cgc7388
Animals fail to respond to the concentration of nicotine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001203
nicotine resistant
Animals fail to respond to the concentration of nicotine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
WB:cab
WB:cgc7388
Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001204
muscimol resistant
Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals respond to muscimol at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001205
muscimol hypersensitive
Animals respond to muscimol at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Variations in the process by which an organism travels from one location to another compared to control.
movement abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001206
movement variant
Variations in the process by which an organism travels from one location to another compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in a series of protein mediated signals that help relay information within the cell, and thereby affecting changes in the functioning of the cell, compared to control.
protein signaling abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001207
protein signaling variant
Any variation in a series of protein mediated signals that help relay information within the cell, and thereby affecting changes in the functioning of the cell, compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals show reduced susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control.
Rde
RNAi deficient
C_elegans_phenotype_ontology
WBPhenotype:0001208
RNAi resistant
Animals show reduced susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control.
WB:WBPerson2021
Apparently normal sinusoidal movement, but appear to have poor traction on the agar surface of a culture plate.
Skd
C_elegans_phenotype_ontology
WBPhenotype:0001209
skiddy
Apparently normal sinusoidal movement, but appear to have poor traction on the agar surface of a culture plate.
WB:WBPaper00026735
WB:cab
Animals exhibit variations in any physical or chemical process taking place in extracellular spaces within or associated with the organism, from that observed for control animals.
pericellular component physiology abnormal
pericellular component physiology variant
C_elegans_phenotype_ontology
WBPhenotype:0001210
pericellular component physiology phenotype
Animals exhibit variations in any physical or chemical process taking place in extracellular spaces within or associated with the organism, from that observed for control animals.
WB:WBPerson712
The physical strength or function of the cuticle varies from that observed for control animals.
cuticle integrity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001211
cuticle integrity variant
The physical strength or function of the cuticle varies from that observed for control animals.
WB:WBPerson712
The strength of the cuticle is less robust than that observed for control animals. In C. elegans the strength of the cuticle is often assayed by it's ability to protect the animal from exposure to bleach or other compounds.
C_elegans_phenotype_ontology
WBPhenotype:0001212
cuticle fragile
The strength of the cuticle is less robust than that observed for control animals. In C. elegans the strength of the cuticle is often assayed by it's ability to protect the animal from exposure to bleach or other compounds.
WB:WBPerson712
Animals exhibit a decrease in any parameter used to measure locomotion compared to control animals.
WBPhenotype:0001288
movement reduced
C_elegans_phenotype_ontology
WBPhenotype:0001213
locomotion reduced
Animals exhibit a decrease in any parameter used to measure locomotion compared to control animals.
WB:cab
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0001214
obsolete metaphase to anaphase transition fails
true
OBSOLETE.
WB:WBPerson557
Variations in the mitotic expansion of germ cell populations or in the appearance of nuclei during development in the premeiotic region of the germline compared to control.
germ cell mitosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001215
germ cell mitosis variant
Variations in the mitotic expansion of germ cell populations or in the appearance of nuclei during development in the premeiotic region of the germline compared to control.
WB:WBPaper00001007
WB:WBPaper00005486
WB:WBPerson2021
Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies.
Mat
C_elegans_phenotype_ontology
WBPhenotype:0001216
meiosis metaphase to anaphase transition block
Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies.
WB:cab
pmid:11134076
Germ line cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001217
germ cell mitosis metaphase to anaphase transition block
Germ line cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control.
WB:WBPerson712
Animals exhibit variations in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations.
cell death sexually dimorphic abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001218
cell death sexually dimorphic variant
Animals exhibit variations in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations.
WB:WBPerson712
Animals exhibit a decrease in the rate or extent of programmed cell death and thus an increase in cell survival, as it pertains to a sex-specific feature, compared to control populations.
C_elegans_phenotype_ontology
WBPhenotype:0001219
cell survival sexually dimorphic increased
Animals exhibit a decrease in the rate or extent of programmed cell death and thus an increase in cell survival, as it pertains to a sex-specific feature, compared to control populations.
WB:WBPerson712
Animals exhibit in increase in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations.
C_elegans_phenotype_ontology
WBPhenotype:0001220
cell death sexually dimorphic increased
Animals exhibit in increase in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations.
WB:WBPerson712
Animal fails to exhibit characteristic response after a nose-on collision with an object compared to control. In C. elegans, this is usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal.
Not
C_elegans_phenotype_ontology
WBPhenotype:0001221
nose touch defective
Animal fails to exhibit characteristic response after a nose-on collision with an object compared to control. In C. elegans, this is usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal.
WB:WBPaper00001705
WB:WBPerson557
Animals exhibit an increase in frequency of transposition events (DNA movement to different positions within the genome of a single cell) causing an accumulation of lesions within the genome, compared to control.
C_elegans_phenotype_ontology
Mut
mutator
WBPhenotype:0001222
transposon mutator
Animals exhibit an increase in frequency of transposition events (DNA movement to different positions within the genome of a single cell) causing an accumulation of lesions within the genome, compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals show reduced susceptibility to gene silencing in the germline triggered by double stranded RNA (RNAi), compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001223
germline RNAi resistant
Animals show reduced susceptibility to gene silencing in the germline triggered by double stranded RNA (RNAi), compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the processes that govern the extension of axons compared to control.
axon outgrowth abnormal
C_elegans_phenotype_ontology
axon migration variant
WBPhenotype:0001224
axon outgrowth variant
Any variation in the processes that govern the extension of axons compared to control.
GO:0048675
WB:WBPerson2021
Animals are missing the interfacial hypodermal cell (socket cell) of the phasmid sensillum pore.
C_elegans_phenotype_ontology
Psa
WBPhenotype:0001225
phasmid socket absent
Animals are missing the interfacial hypodermal cell (socket cell) of the phasmid sensillum pore.
WB:WBPaper00000938
WB:WBPaper00004350
WB:WBPaper00026656
WB:WBPerson712
Animals display variations in the structure, organization or path of the part of the axon that forms a bridge between body regions, compared to that in control animals.
commissure abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001226
commissure variant
Animals display variations in the structure, organization or path of the part of the axon that forms a bridge between body regions, compared to that in control animals.
WB:WBPaper00000938
WB:WBPaper00001576
WB:WBPaper00029065
WB:WBPerson712
Animals are missing any one of its commissures, an axon tract that connects one body part to another.
C_elegans_phenotype_ontology
WBPhenotype:0001227
commissure absent
Animals are missing any one of its commissures, an axon tract that connects one body part to another.
WB:WBPaper00027335
WB:WBPerson712
Animals lack the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0001228
alae absent
Animals lack the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The orderly movement of neurons along the anterior axis of the animal is abolished, misdirected or incomplete compared to control.
abnormal anterior neuron migration
C_elegans_phenotype_ontology
WBPhenotype:0001229
anterior neuron migration defective
The orderly movement of neurons along the anterior axis of the animal is abolished, misdirected or incomplete compared to control.
WB:WBPerson2021
The orderly movement of cells along the anterior axis of the animal is abolished, misdirected or incomplete compared to control.
abnormal anterior cell migration
C_elegans_phenotype_ontology
WBPhenotype:0001230
anterior cell migration defective
The orderly movement of cells along the anterior axis of the animal is abolished, misdirected or incomplete compared to control.
WB:WBPerson2021
The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is increased compared to control.
C_elegans_phenotype_ontology
ift accelerated
WBPhenotype:0001231
intraflagellar transport accelerated
The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is increased compared to control.
WB:WBPerson2021
Animals exhibit variations in the response to the addition of serotonin compared to that observed in control animals. Serotonin is a monoamine neurotransmitter.
serotonin response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001232
serotonin response variant
Animals exhibit variations in the response to the addition of serotonin compared to that observed in control animals. Serotonin is a monoamine neurotransmitter.
WB:WBPerson557
Animals exhibit variations in the pattern of a chemical nuclear stain which is commonly used in fixed specimens and produces a bright blue label, compared to control. DAPI (4'-6-Diamidino-2-phenylindole) forms fluorescent complexes with natural double-stranded DNA (Wormatlas).
DAPI staining abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001233
DAPI staining variant
Animals exhibit variations in the pattern of a chemical nuclear stain which is commonly used in fixed specimens and produces a bright blue label, compared to control. DAPI (4'-6-Diamidino-2-phenylindole) forms fluorescent complexes with natural double-stranded DNA (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Failure to execute the characteristic response to nonanone compared to control. In C. elegans, nonanone is a repellant.
C_elegans_phenotype_ontology
WBPhenotype:0001234
nonanone chemotaxis defective
Failure to execute the characteristic response to nonanone compared to control. In C. elegans, nonanone is a repellant.
WB:WBPaper00002917
Any variation in the orientation of the physical partitioning and separation of a cell into daughter cells compared to control.
cell division polarity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001235
cell division polarity variant
Any variation in the orientation of the physical partitioning and separation of a cell into daughter cells compared to control.
WB:WBPerson2021
WB:WBPerson557
Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001236
transgene expression increased
Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WB:WBPerson557
Any perturbation that causes an increase in the frequency of axon outgrowth compared to control. As a result, an excess number of axonal projections are generated.
C_elegans_phenotype_ontology
WBPhenotype:0001237
excess axon outgrowth
Any perturbation that causes an increase in the frequency of axon outgrowth compared to control. As a result, an excess number of axonal projections are generated.
GO:0030517
WB:WBPerson2021
Any variation in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva.
male mating latency abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001238
male mating latency variant
Any variation in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva.
WB:cab
pmid:16624900
Any increase in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva.
C_elegans_phenotype_ontology
WBPhenotype:0001239
mating latency increased
Any increase in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva.
pmid:16624900
Variations in the processes leading to the specialization of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control.
male tail sensory ray differentiation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001240
male tail sensory ray differentiation variant
Variations in the processes leading to the specialization of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0001241
obsolete ray fusion
true
The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is lower compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001242
intraflagellar transport slow
The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is lower compared to control.
WB:WBPerson2021
The bidirectional transport of molecules (cargo) along axonemal microtubules is reduced compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001243
intraflagellar transport distance short
The bidirectional transport of molecules (cargo) along axonemal microtubules is reduced compared to control.
WB:WBPerson2021
WB:WBPerson557
Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is completely abolished.
C_elegans_phenotype_ontology
WBPhenotype:0001244
intraflagellar transport absent
Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is completely abolished.
WB:WBPerson2021
The bidirectional transport of molecules along the middle segment of axonemal microtubules of the cilia is absent.
C_elegans_phenotype_ontology
WBPhenotype:0001245
no transport middle segment cilia
The bidirectional transport of molecules along the middle segment of axonemal microtubules of the cilia is absent.
WB:WBPerson2021
WB:WBPerson557
The bidirectional transport of molecules along the distal segment of axonemal microtubules of the cilia is absent.
C_elegans_phenotype_ontology
WBPhenotype:0001246
no transport distal segment cilia
The bidirectional transport of molecules along the distal segment of axonemal microtubules of the cilia is absent.
WB:WBPerson2021
WB:WBPerson557
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons is disrupted.
C_elegans_phenotype_ontology
WBPhenotype:0001247
Possible XP.
anterograde transport defective
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons is disrupted.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure or organization of the microtuble-based projections that in control animals invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In C. elegans, the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes.
wing cilia morphology abnormal
C_elegans_phenotype_ontology
AWC cilia morphology abnormal
WBPhenotype:0001248
wing cilia morphology variant
Animals exhibit variations in the structure or organization of the microtuble-based projections that in control animals invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In C. elegans, the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes.
WB:WBPaper00000932
WB:WBPaper00029016
WB:WBPerson712
Animals exhibit variations in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in control animals. In C. elegans, amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO.
amphid channel cilia morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001249
amphid channel cilia morphology variant
Animals exhibit variations in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in control animals. In C. elegans, amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO.
WB:WBPaper00000932
WB:WBPerson712
Animals exhibit variations in the structure or composition of the microtuble-based fibrillar core, axoneme, of the cilia of the neurons that project through the sensillum pore to the outside of the animal, compared to that observed in control animals.
amphid channel axoneme morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001250
amphid channel axoneme morphology variant
Animals exhibit variations in the structure or composition of the microtuble-based fibrillar core, axoneme, of the cilia of the neurons that project through the sensillum pore to the outside of the animal, compared to that observed in control animals.
WB:WBPaper00000932
WB:WBPerson557
WB:WBPerson712
The microtuble-based fibrillar-bundles of the amphid sensory cilia are reduced in length compared to those in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001251
amphid channel axoneme short
The microtuble-based fibrillar-bundles of the amphid sensory cilia are reduced in length compared to those in control animals.
WB:WBPaper00000932
WB:WBPaper00027116
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in the structure or organization of the microtubule-based fibrillar section, axoneme, of the cilia of the flat sheet-like cells associated with sensory function, from that observed in control animals.
wing cilia axoneme morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001252
wing cilia axoneme morphology variant
Animals exhibit variations in the structure or organization of the microtubule-based fibrillar section, axoneme, of the cilia of the flat sheet-like cells associated with sensory function, from that observed in control animals.
WB:WBPerson712
The microtuble-based fibrillar-bundle, axoneme, of the wing cell cilia are reduced in length and do not extend into the sheath cell as far as they do in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001253
wing cilia axoneme short
The microtuble-based fibrillar-bundle, axoneme, of the wing cell cilia are reduced in length and do not extend into the sheath cell as far as they do in control animals.
WB:WBPerson712
The dendritic processes that normally extend through the amphid sensillum pore to the outside are truncated and have swollen ends as opposed to the extended and finger-like tips of channel cilia in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001254
amphid channel cilia bulbous
The dendritic processes that normally extend through the amphid sensillum pore to the outside are truncated and have swollen ends as opposed to the extended and finger-like tips of channel cilia in control animals.
WB:WBPaper00027116
WB:WBPerson712
Animals exhibit wing cell sensory cilia that are truncated and swollen unlike that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001255
wing cilia bulbous
Animals exhibit wing cell sensory cilia that are truncated and swollen unlike that observed in control animals.
WB:WBPaper00027116
WB:WBPerson712
Variations in the aggregation of molecules at the site of DNA strand breakage or damage compared to control.
DNA damage induced focus formation abnormal
C_elegans_phenotype_ontology
DNA repair induced focus formation
WBPhenotype:0001256
DNA damage induced focus formation variant
Variations in the aggregation of molecules at the site of DNA strand breakage or damage compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the generation of foci that mark sites of aberrant bonding of molecules to the DNA strand, compared to control.
cross link induced focus formation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001257
cross link induced focus formation variant
Variations in the generation of foci that mark sites of aberrant bonding of molecules to the DNA strand, compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals show increased susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control.
C_elegans_phenotype_ontology
Eri
WBPhenotype:0001258
RNAi enhanced
Animals show increased susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control.
WB:WBPerson2021
Hermaphrodites exhibit a reduction in the production of new individuals owing to defects in gamete competence and/or function compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001259
hermaphrodite fertility reduced
Hermaphrodites exhibit a reduction in the production of new individuals owing to defects in gamete competence and/or function compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control.
oocyte morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001260
oocyte morphology variant
Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control.
WB:WBPaper00001883
WB:WBPerson2021
Animals show deficiencies in chroma resulting in increased translucency.
C_elegans_phenotype_ontology
WBPhenotype:0001261
pale
Animals show deficiencies in chroma resulting in increased translucency.
WB:WBPerson2021
WB:WBPerson557
The developmental progression of the egg-laying organ of female and hermaphrodite nematodes is halted prior to the formation of the mature structure.
C_elegans_phenotype_ontology
WBPhenotype:0001262
vulval development incomplete
The developmental progression of the egg-laying organ of female and hermaphrodite nematodes is halted prior to the formation of the mature structure.
WB:WBPerson2021
WB:WBPerson557
The morphological appearance of peroxisomes is variant compared to control animals.
peroxisome morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001263
peroxisome morphology variant
The morphological appearance of peroxisomes is variant compared to control animals.
WB:cab
Animals exhibit variations in any physical or chemical process required for the peroxisome to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
peroxisome physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001264
peroxisome physiology variant
Animals exhibit variations in any physical or chemical process required for the peroxisome to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
The anterior portion of the animal exhibits variations in its movement compared to control.
Erratic head vibration
head movement abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001265
head movement variant
The anterior portion of the animal exhibits variations in its movement compared to control.
WB:WBPaper00000214
Any variation in triggering of the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control.
genetic pathway activation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001266
genetic pathway activation variant
Any variation in triggering of the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the frequency of gonad sheath contractions triggered by internal or external stimuli compared to control.
induced contraction rate abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001267
induced contraction rate variant
Any variation in the frequency of gonad sheath contractions triggered by internal or external stimuli compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the extent of activation of programmed cell death, compared to control.
induced cell death abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001268
induced cell death variant
Animals exhibit variations in the extent of activation of programmed cell death, compared to control.
WB:WBPerson712
Animals exhibit variations in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
pathogen induced cell death abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001269
pathogen induced cell death variant
Animals exhibit variations in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
WB:WBPerson712
Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001270
pathogen induced cell death reduced
Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
WB:WBPerson712
Animals are more prone to lethality as a result of infection compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001271
pathogen induced death increased
Animals are more prone to lethality as a result of infection compared to control.
WB:WBPerson2021
WB:WBPerson557
Vulval precursor cells inappropriately adopt fates that are normally restricted to other vulval precursor cells compared to control.
vulval precursor cell induction abnormal
vulval cell induction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001272
vulval cell induction variant
Vulval precursor cells inappropriately adopt fates that are normally restricted to other vulval precursor cells compared to control.
WB:WBPerson2021
Any variation in the state or activity of an organism (in terms of movement, gene expression, etc.) in response to heat (high temperatures above the optimal temperature for that organism), compared to control.
organism heat response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001273
organism heat response variant
Any variation in the state or activity of an organism (in terms of movement, gene expression, etc.) in response to heat (high temperatures above the optimal temperature for that organism), compared to control.
GO:0009408
WB:WBPerson2021
Animals respond to heat at a lower temperature or a shorter exposure time compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001274
organism heat hypersensitive
Animals respond to heat at a lower temperature or a shorter exposure time compared to control animals.
WB:WBPerson557
Any variation that increases the magnitude of a signal generated by a set of gene interactions in a given pathway, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001275
increased genetic pathway signal
Any variation that increases the magnitude of a signal generated by a set of gene interactions in a given pathway, compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001276
ectopic expression transgene
Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals.
WB:WBPerson557
XX animals are transformed into males or pseudomales .
C_elegans_phenotype_ontology
Tra
WBPhenotype:0001277
transformer
XX animals are transformed into males or pseudomales .
WB:WBPerson712
WB:cab
Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001278
transgene expression reduced
Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WB:WBPerson557
Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the male, that has been introduced into the organism compared to its expression in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001279
transgene expression reduced male
Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the male, that has been introduced into the organism compared to its expression in control animals.
WB:WBPerson557
Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the hermaphrodite, that has been introduced into the organism compared to its expression in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001280
transgene expression reduced hermaphrodite
Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the hermaphrodite, that has been introduced into the organism compared to its expression in control animals.
WB:WBPerson557
Pharynx becomes clogged with food. In C. elegans, this is often a result of pharyngeal pumping defects.
C_elegans_phenotype_ontology
WBPhenotype:0001281
stuffed pharynx
Pharynx becomes clogged with food. In C. elegans, this is often a result of pharyngeal pumping defects.
WB:cab
Variations in the chemical reactions and pathways of the mitochondria compared to control.
mitochondrial metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001282
mitochondrial metabolism variant
Variations in the chemical reactions and pathways of the mitochondria compared to control.
WB:WBPerson2021
Variations in the chemical reactions and pathways of an organelle compared to control.
organelle metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001283
organelle metabolism variant
Variations in the chemical reactions and pathways of an organelle compared to control.
WB:WBPerson2021
Animals contain a lower level of coenzyme Q, an oil-soluble vitamin-like substance present in most eukaryotic cells, primarily in the mitochondria, compared to control. It is a component of the electron transport chain and participates in aerobic cellular respiration.
C_elegans_phenotype_ontology
WBPhenotype:0001284
coenzyme Q depleted
Animals contain a lower level of coenzyme Q, an oil-soluble vitamin-like substance present in most eukaryotic cells, primarily in the mitochondria, compared to control. It is a component of the electron transport chain and participates in aerobic cellular respiration.
WB:WBPerson2021
WB:WBPerson557
Pharyngeal pumping is not influenced by treatment with specific compounds (eg: serotonin) in the same manner as control animals.
induced pharyngeal pumping abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001285
induced pharyngeal pumping variant
Pharyngeal pumping is not influenced by treatment with specific compounds (eg: serotonin) in the same manner as control animals.
WB:WBPerson2021
Exposure to food does not reduce pharyngeal pumping to the same extent as observed in control animals.
food suppressed pumping abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001286
food suppressed pumping variant
Exposure to food does not reduce pharyngeal pumping to the same extent as observed in control animals.
WB:WBPerson2021
Animals do not exhibit a decrease in pumping rate when treated with specific compounds (such as pheromones) as is observed for control animals.
suppressed pharyngeal pumping abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001287
suppressed pharyngeal pumping defective
Animals do not exhibit a decrease in pumping rate when treated with specific compounds (such as pheromones) as is observed for control animals.
WB:WBPaper00032082
WB:WBPerson712
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0001288
is alternative id for "locomotion reduced" (WBPhenotype:0001213); may have originally had term name "movement reduced"
true
Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001289
acetylcholinesterase inhibitor resistant
Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals.
acetylcholinesterase inhibitor response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001290
acetylcholinesterase inhibitor response variant
Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals.
WB:WBPerson557
Animals exhibit variations in actions and responses that occurs predominantly, or only, in individuals that are part of a group, from that observed for animals in a control group.
social behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001291
social behavior variant
Animals exhibit variations in actions and responses that occurs predominantly, or only, in individuals that are part of a group, from that observed for animals in a control group.
GO:0035176
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the body wall muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
body wall muscle physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001292
body wall muscle physiology variant
Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the body wall muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the larva to carry out its normal metabolic functions or activities or be able to perceive and respond to stimuli, compared to control animals.
larval physiology abnormal
larval physiology variant
C_elegans_phenotype_ontology
WBPhenotype:0001293
larval physiology phenotype
Animals exhibit variations in any physical or chemical process required for the larva to carry out its normal metabolic functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson712
The most anterior portion of the animal is not aligned with the axis of the body.
C_elegans_phenotype_ontology
WBPhenotype:0001294
head bent
The most anterior portion of the animal is not aligned with the axis of the body.
WB:WBPaper00000031
Any portion of the animal, between the head and the tail, appears distorted, usually due to uncharacteristic winding.
C_elegans_phenotype_ontology
WBPhenotype:0001295
body twisted
Any portion of the animal, between the head and the tail, appears distorted, usually due to uncharacteristic winding.
WB:WBPerson2021
WB:WBPerson557
Animals fail to respond to the concentration of lannate that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
methomyl resistant
C_elegans_phenotype_ontology
WBPhenotype:0001296
lannate resistant
Animals fail to respond to the concentration of lannate that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Any variation in the process whose specific outcome is the progression of the male tail over time, from its formation to the mature structure, compared to control.
male tail development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001297
male tail development variant
Any variation in the process whose specific outcome is the progression of the male tail over time, from its formation to the mature structure, compared to control.
WB:WBPerson2021
Animals exhibit variations in the form, structure or composition of the more posterior portion of the intestine, just anterior to the sphincter valve, which is subject to squeezing by the somatal-intestinal muscles compared to control animals (Wormatlas).
hindgut morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001298
hindgut morphology variant
Animals exhibit variations in the form, structure or composition of the more posterior portion of the intestine, just anterior to the sphincter valve, which is subject to squeezing by the somatal-intestinal muscles compared to control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation that alters the physical partitioning and separation of a cell into daughter cells in male animals compared to control.
cell division abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001299
cell division variant male
Any variation that alters the physical partitioning and separation of a cell into daughter cells in male animals compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the composition or structure of the contents within a germ cell, excluding the plasma membrane and nucleus, compared to control. Germ cells include sperm, oocytes, and their precursors.
germ cell cytoplasmic morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001300
germ cell cytoplasmic morphology variant
Any variation in the composition or structure of the contents within a germ cell, excluding the plasma membrane and nucleus, compared to control. Germ cells include sperm, oocytes, and their precursors.
GO:0005737
WB:WBPerson2021
WB:WBPerson557
Localization or structural appearance of P-granules is altered compared to control. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle.
C_elegans_phenotype_ontology
WBPhenotype:0001301
P granule abnormal
Localization or structural appearance of P-granules is altered compared to control. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle.
WB:cab
pmid:11262230
The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control.
P granule localization abnormal
C_elegans_phenotype_ontology
germ granule localization defective
WBPhenotype:0001302
P granule localization defective
The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control.
WB:WBPaper00001477
WB:WBPerson2021
Animals have one or more extra cells of a particular type, which are present in places they are normally not found, when compared to the number and location of these cells in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001303
extra and ectopic cell
Animals have one or more extra cells of a particular type, which are present in places they are normally not found, when compared to the number and location of these cells in control animals.
WB:WBPerson2021
WB:WBPerson557
The terminal portion of the intestine exhibits structural defects such as scarring or blockage.
Scar
C_elegans_phenotype_ontology
WBPhenotype:0001304
hindgut damaged
The terminal portion of the intestine exhibits structural defects such as scarring or blockage.
WB:WBPaper00003719
WB:cab
Any variation in the form or composition of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating.
hook morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001305
hook morphology variant
Any variation in the form or composition of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating.
WB:WBPerson2021
WB:WBPerson557
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the male reproductive system compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
male reproductive system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001306
male reproductive system morphology variant
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the male reproductive system compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
WB:WBPerson2021
WB:WBPerson557
The maximum ventral and dorsal flex of the animal is reduced compared to that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001307
reduced body bend
The maximum ventral and dorsal flex of the animal is reduced compared to that observed for control animals.
WB:WBPerson2021
WB:WBPerson557
The contraction and relaxation movements of the pharyngeal muscle that mediate feeding is not as robust as compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001308
weak pumping
The contraction and relaxation movements of the pharyngeal muscle that mediate feeding is not as robust as compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit a decrease in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control.
WBPhenotype:0000003
amplitude of body bends decreased
flat locomotion path
flattened locomotion path
C_elegans_phenotype_ontology
WBPhenotype:0001309
amplitude of sinusoidal movement decreased
Animals exhibit a decrease in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control.
WB:WBPaper00043908
WB:WBPerson2021
WB:WBPerson2987
WB:WBPerson557
The placement of neuronal cells, as a whole or of a specific class of neuron in the animal, deviates from that observed in control animals.
neuron positioning abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001310
neuron positioning variant
The placement of neuronal cells, as a whole or of a specific class of neuron in the animal, deviates from that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Variations that result in a decrease in protein expression in hermaphrodites compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001311
protein expression reduced hermaphrodite
Variations that result in a decrease in protein expression in hermaphrodites compared to that observed in control animals.
WB:WBPerson2021
The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals.
neuron number abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001312
neuron number variant
The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals.
WB:WBPaper00027711
WB:WBPerson712
Any variation in the progression of the sex-specific muscles of the hermaphrodite, over time, whose contractions squeeze on the uterus to help move eggs towards the vulval opening compared to control (Wormatlas).
uterine muscle abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001313
uterine muscle variant
Any variation in the progression of the sex-specific muscles of the hermaphrodite, over time, whose contractions squeeze on the uterus to help move eggs towards the vulval opening compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the sex-specific muscles in the hermaphrodite, over time, that are specialized for egg-laying compared to control. In C. elegans the contractions of the vulval muscles open the lips of the vulva to help in expelling an egg from the uterus (Wormatlas).
vulval muscle abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001314
vulval muscle variant
Any variation in the progression of the sex-specific muscles in the hermaphrodite, over time, that are specialized for egg-laying compared to control. In C. elegans the contractions of the vulval muscles open the lips of the vulva to help in expelling an egg from the uterus (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the electrical properties of any of its cells or tissues compared to control.
electrophysiology abnormal
electrophysiology variant
C_elegans_phenotype_ontology
WBPhenotype:0001315
electrophysiology phenotype
Animals exhibit variations in the electrical properties of any of its cells or tissues compared to control.
WB:WBPerson2021
Variations in the synaptic currents that are elicited by firing an action potential in a population of axons, compared to control.
evoked postsynaptic current abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001316
evoked postsynaptic current variant
Variations in the synaptic currents that are elicited by firing an action potential in a population of axons, compared to control.
WB:WBPerson2021
pmid:14735116
The amplitudes of synaptic currents that are elicited by firing an action potential in a population of axons are decreased, compared to those observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001317
evoked postsynaptic amplitude reduced
The amplitudes of synaptic currents that are elicited by firing an action potential in a population of axons are decreased, compared to those observed in control animals.
WB:WBPerson2021
Any variation in the currents observed in the absence of presynaptic action potentials and that are elicited by fusion of a single endogenous vesicle of transmitter compared to control.
endogenous synaptic events abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001318
endogenous synaptic events variant
Any variation in the currents observed in the absence of presynaptic action potentials and that are elicited by fusion of a single endogenous vesicle of transmitter compared to control.
WB:WBPerson2021
pmid:14735116
The rate (frequency) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is decreased compared to control. Changes in frequency are indicative of presynaptic modifications.
C_elegans_phenotype_ontology
WBPhenotype:0001319
endogenous synaptic event frequency reduced
The rate (frequency) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is decreased compared to control. Changes in frequency are indicative of presynaptic modifications.
WB:WBPaper00026938
WB:WBPerson2021
pmid:14735116
The amplitude (magnitude) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is altered compared to control. Changes in amplitude are often interpreted as alterations of postsynaptic responsiveness to the transmitter.
endogenous synaptic amplitude abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001320
endogenous synaptic amplitude variant
The amplitude (magnitude) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is altered compared to control. Changes in amplitude are often interpreted as alterations of postsynaptic responsiveness to the transmitter.
WB:WBPerson2021
pmid:14735116
Animals display variations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse compared to control.
presynaptic region morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001321
presynaptic region morphology variant
Animals display variations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse compared to control.
GO:0042734
WB:WBPaper00000938
WB:WBPaper00027305
WB:WBPaper00028886
WB:WBPerson712
OBSOLETE. Total presynaptic vesicle number is reduced, possibly refecting a defect in the replenishment of synaptic vesicles compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001322
Electron microscopic analysis.
obsolete vesicle number reduced
true
OBSOLETE. Total presynaptic vesicle number is reduced, possibly refecting a defect in the replenishment of synaptic vesicles compared to control.
WB:cab
pmid:16803962
Animals display variations in the shape or size of their vesicles, which are spherical, membrane-bound fluid-filled organelles, compared to vesicles observed in control animals.
vesicle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001323
Electron microscopic analysis.
vesicle morphology variant
Animals display variations in the shape or size of their vesicles, which are spherical, membrane-bound fluid-filled organelles, compared to vesicles observed in control animals.
GO:0031982
WB:WBPaper00027612
WB:WBPaper00027711
WB:WBPerson712
WB:cab
pmid:16803962
Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals.
cell ionizing radiation response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001324
cell ionizing radiation response variant
Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals.
WB:WBPerson557
Animals initiate but do not continue backward movement, similar to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001325
backing not sustained
Animals initiate but do not continue backward movement, similar to control animals.
WB:cab
WB:cgc914
Cells exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
cell gamma ray response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001326
cell gamma ray response variant
Cells exhibit variations in their response to gamma ray radiation compared to that observed in control animals.
WB:WBPerson557
Cells respond to a lower dosage of gamma rays or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001327
cell gamma ray hypersensitive
Cells respond to a lower dosage of gamma rays or a shorter exposure compared to control animals.
WB:WBPerson557
The posterior part of the worm is shorter and stouter compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001328
posterior body dumpy
The posterior part of the worm is shorter and stouter compared to control animals.
WB:WBPerson557
Animals exhibit a greater number of bends in their body compared to control. C. elegans posture assumes more than a single sine wave.
C_elegans_phenotype_ontology
WBPhenotype:0001329
curly
Animals exhibit a greater number of bends in their body compared to control. C. elegans posture assumes more than a single sine wave.
WB:cab
WB:cgc914
The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate is reduced compared to that observed in control animals (Wormatlas).
C_elegans_phenotype_ontology
egg laying event rare
WBPhenotype:0001330
egg laying event infrequent
The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate is reduced compared to that observed in control animals (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals display variations in the structure or organization of components of the motor neuron, internal to the cell itself or in relation to the cellular environment compared to that observed in control animals. A motor neuron is a neuronal cell that synapses to an effector (muscle, gland etc.).
motor neuron morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001331
WBbt:0005409.
motor neuron morphology variant
Animals display variations in the structure or organization of components of the motor neuron, internal to the cell itself or in relation to the cellular environment compared to that observed in control animals. A motor neuron is a neuronal cell that synapses to an effector (muscle, gland etc.).
WB:WBPerson712
Animals display variations in the number of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals.
vesicle number abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001332
vesicle number variant
Animals display variations in the number of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced.
C_elegans_phenotype_ontology
WBPhenotype:0001333
neuron cell body absent misplaced
The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced.
WB:WBPaper00000502
WB:WBPaper00000635
WB:WBPerson712
Any variation in the form, structure or composition of the muscles of the adult hermaphrodite reproductive system compared to control. In C. elegans hermaphrodites these muscles include the vulval and uterine muscles, located near the vulva in the midbody, which all derive from the M myoblast (Wormatlas).
hermaphrodite sex muscle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001334
hermaphrodite sex muscle morphology variant
Any variation in the form, structure or composition of the muscles of the adult hermaphrodite reproductive system compared to control. In C. elegans hermaphrodites these muscles include the vulval and uterine muscles, located near the vulva in the midbody, which all derive from the M myoblast (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the hermaphrodite reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
hermaphrodite reproductive system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001335
hermaphrodite reproductive system morphology variant
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the hermaphrodite reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents.
WB:WBPerson2021
WB:WBPerson557
Males sire no cross progeny.
no male progeny
C_elegans_phenotype_ontology
WBPhenotype:0001336
male mating efficiency eliminated
Males sire no cross progeny.
WB:WBPaper00000179
WB:WBPaper00000608
WB:WBPerson557
Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals.
adrenergic receptor antagonist response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001337
adrenergic receptor antagonist response variant
Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals.
WB:WBPerson557
Animals fail to respond to the concentration of phentolamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001338
phentolamine resistant
Animals fail to respond to the concentration of phentolamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals are not induced to lay eggs in reponse to exogenous levamisole. In C. elegans, levamisole stimulates egg-laying.
C_elegans_phenotype_ontology
WBPhenotype:0001339
egg laying levamisole resistant
Animals are not induced to lay eggs in reponse to exogenous levamisole. In C. elegans, levamisole stimulates egg-laying.
WB:WBPaper00000635
WB:WBPerson712
Animals are not induced to lay eggs in reponse to exogenous imipramine. In C. elegans, imipramine stimulates egg-laying.
C_elegans_phenotype_ontology
WBPhenotype:0001340
egg laying imipramine resistant
Animals are not induced to lay eggs in reponse to exogenous imipramine. In C. elegans, imipramine stimulates egg-laying.
WB:WBPaper00000635
WB:WBPaper00001133
WB:WBPaper00031293
WB:WBPerson712
Animals are not induced to lay eggs in reponse to exogenous phentolamine. In C. elegans, phentolamine stimulates egg-laying.
C_elegans_phenotype_ontology
WBPhenotype:0001341
egg laying phentolamine resistant
Animals are not induced to lay eggs in reponse to exogenous phentolamine. In C. elegans, phentolamine stimulates egg-laying.
WB:WBPaper00000635
WB:WBPerson712
Animals respond to exogenous imipramine at a lower concentration or within a shorter time period than control animals under the same conditions.
C_elegans_phenotype_ontology
WBPhenotype:0001342
egg laying imipramine hypersensitive
Animals respond to exogenous imipramine at a lower concentration or within a shorter time period than control animals under the same conditions.
WB:WBPaper00000635
WB:WBPerson712
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a meiotic cell cycle.
C_elegans_phenotype_ontology
WBPhenotype:0001343
Possible XP.
meiotic spindle defective early emb
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a meiotic cell cycle.
GO:0000212
WB:WBPerson2021
Intracellular membrane bound compartments vary in shape or size from that observed in control animals.
organelle organization biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001344
organelle organization biogenesis variant
Intracellular membrane bound compartments vary in shape or size from that observed in control animals.
WB:WBPaper00032168
WB:WBPerson712
Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
cytoskeleton organization biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001345
cytoskeleton organization biogenesis variant
Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
GO:0005856
WB:WBPerson2021
WB:WBPerson557
Any variation in the dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins compared to control.
actin cytoskeleton dynamics variant
actin cytoskeleton dynamic abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001346
Possible XP.
actin cytoskeleton dynamics phenotype
Any variation in the dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins compared to control.
GO:0031532
WB:WBPerson2021
WB:WBPerson557
Any variation in the series of molecular signals in which an intestinal cell uses calcium ions to convert an extracellular signal into a response, compared to control.
intestinal calcium signaling abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001347
intestinal calcium signaling variant
Any variation in the series of molecular signals in which an intestinal cell uses calcium ions to convert an extracellular signal into a response, compared to control.
WB:WBPerson2021
WB:WBPerson557
Variations in the form or composition of a structure in the cell nucleus which contains the genetic material encoded as DNA and surrounded by histone proteins and other regulatory elements compared to control. In C. elegans the normal cell contains 5 pairs of 'autosomes' and one or two X chromosomes (Wormatlas).
chromosome morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001348
chromosome morphology variant
Variations in the form or composition of a structure in the cell nucleus which contains the genetic material encoded as DNA and surrounded by histone proteins and other regulatory elements compared to control. In C. elegans the normal cell contains 5 pairs of 'autosomes' and one or two X chromosomes (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the processes that incorporate phosphate groups to one or more amino acids within a protein, compared to control.
protein phosphorylation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001349
protein phosphorylation variant
Variations in the processes that incorporate phosphate groups to one or more amino acids within a protein, compared to control.
GO:0006468
WB:WBPerson2021
Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001350
protein phosphorylation increased
Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals.
WB:WBPerson2021
Animals exhibit decreased levels of protein phosphorylation compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001351
protein phosphorylation reduced
Animals exhibit decreased levels of protein phosphorylation compared to that observed in control animals.
WB:WBPerson2021
Variations in the chemical reactions and pathways of the endoplasmic reticulum compared to control.
endoplasmic reticulum metabolism abnormal
C_elegans_phenotype_ontology
er metabolism abnormal
WBPhenotype:0001352
endoplasmic reticulum metabolism variant
Variations in the chemical reactions and pathways of the endoplasmic reticulum compared to control.
WB:WBPerson2021
The coordinated movement during prophase of the two centrosomes and the two pronuclei towards the center of the one cell embryo is abolished.
centration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001353
centration defective early emb
The coordinated movement during prophase of the two centrosomes and the two pronuclei towards the center of the one cell embryo is abolished.
WB:WBPaper00027230
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
actin cytoskeleton filament morphology abnormal
actin cytoskeleton filament morphology variant
C_elegans_phenotype_ontology
WBPhenotype:0001354
actin cytoskeleton filament morphology phenotype
Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
gonad morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001355
gonad morphology variant
Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the form, structure or composition of the muscles of the adult male reproductive system compared to control. In C. elegans males, the M myoblast gives rise to a much larger set of specialized muscles, compared to hermaphrodites, which differentiate within the tail region (Wormatlas).
male sex muscle morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001356
male sex muscle morphology variant
Any variation in the form, structure or composition of the muscles of the adult male reproductive system compared to control. In C. elegans males, the M myoblast gives rise to a much larger set of specialized muscles, compared to hermaphrodites, which differentiate within the tail region (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male gametes compared to control (Wormatlas).
male gonad morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001357
male gonad morphology variant
Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male gametes compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Male animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals.
male nervous system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001358
male nervous system morphology variant
Male animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the structure and organization of the chamber in the male tail that extends from the termination of four canals (vas deferens, gut, and left and right spicule channels) to just before the cloaca, from that observed in control animals.
proctodeum morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001359
proctodeum morphology variant
Animals exhibit variations in the structure and organization of the chamber in the male tail that extends from the termination of four canals (vas deferens, gut, and left and right spicule channels) to just before the cloaca, from that observed in control animals.
WB:WBPaper00027278
WB:WBPerson712
Hermaphrodites fail to produce any viable progeny via self-fertilization. However, such hermaphrodites can successfully reproduce if mated to control males.
C_elegans_phenotype_ontology
WBPhenotype:0001360
hermaphrodite self sterile
Hermaphrodites fail to produce any viable progeny via self-fertilization. However, such hermaphrodites can successfully reproduce if mated to control males.
WB:WBPaper00001075
WB:WBPerson2021
Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control.
chromosome condensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001361
chromosome condensation variant
Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control.
GO:0030261
WB:WBPerson2021
WB:WBPerson557
The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis in eukaryotic cells is abolished.
C_elegans_phenotype_ontology
WBPhenotype:0001362
chromosome condensation failure
The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis in eukaryotic cells is abolished.
GO:0030261
WB:WBPerson2021
WB:WBPerson557
The head contains cavities, possibly indicative of inappropriate cell death.
C_elegans_phenotype_ontology
head vacuole
WBPhenotype:0001363
head cavity
The head contains cavities, possibly indicative of inappropriate cell death.
WB:cab
Any variation in the form, structure or composition of the flattened structure extending laterally at the extreme tip of the adult male consisting of nine pairs of sensory rays that lie within a web-like cuticle compared to control.
male fan morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001364
male fan morphology variant
Any variation in the form, structure or composition of the flattened structure extending laterally at the extreme tip of the adult male consisting of nine pairs of sensory rays that lie within a web-like cuticle compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the process whose specific outcome is the progression of the male bursa over time, from its formation to the mature structure, compared to control. The male bursa consists of the lateral fan and rays (WormAtlas).
male bursa development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001365
male bursa development variant
Any variation in the process whose specific outcome is the progression of the male bursa over time, from its formation to the mature structure, compared to control. The male bursa consists of the lateral fan and rays (WormAtlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the process whose specific outcome is the progression of the male fan over time, from its formation to the mature structure, compared to control.
male fan development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001366
male fan development variant
Any variation in the process whose specific outcome is the progression of the male fan over time, from its formation to the mature structure, compared to control.
WB:WBPerson2021
Any variation in the process whose specific outcome is the progression of the male proctodeum over time, from its formation to the mature structure, compared to control. The union of the vas deferens and the intestine give rise to the proctodeum which contains copulatory spicules.
proctodeum development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001367
proctodeum development variant
Any variation in the process whose specific outcome is the progression of the male proctodeum over time, from its formation to the mature structure, compared to control. The union of the vas deferens and the intestine give rise to the proctodeum which contains copulatory spicules.
WB:WBPerson2021
Animals lack the somatic gonad structure that connects the distal gonad arm to the uterus.
C_elegans_phenotype_ontology
WBPhenotype:0001368
spermatheca absent
Animals lack the somatic gonad structure that connects the distal gonad arm to the uterus.
WB:WBPerson2021
WB:WBPerson557
Variations in the selective and non-covalent physical association between two or more proteins, or a protein and nucleic acid/macromolecular complex, compared to control.
protein interaction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001369
protein interaction variant
Variations in the selective and non-covalent physical association between two or more proteins, or a protein and nucleic acid/macromolecular complex, compared to control.
GO:0005515
WB:WBPerson2021
Variations in the selective and non-covalent physical association between two or more proteins, compared to control.
protein protein interaction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001370
protein protein interaction variant
Variations in the selective and non-covalent physical association between two or more proteins, compared to control.
WB:WBPerson2021
Variations in the selective and non-covalent physical association between a protein and a specific RNA sequence, compared to control.
protein RNA interaction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001371
protein RNA interaction variant
Variations in the selective and non-covalent physical association between a protein and a specific RNA sequence, compared to control.
WB:WBPerson2021
Variations in the selective and non-covalent physical association between a protein and a specific DNA sequence, compared to control.
protein DNA interaction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001372
protein DNA interaction variant
Variations in the selective and non-covalent physical association between a protein and a specific DNA sequence, compared to control.
WB:WBPerson2021
Animals lack a specific protein-RNA interaction observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001373
protein RNA interaction abolished
Animals lack a specific protein-RNA interaction observed in control animals.
WB:WBPerson2021
The shape and size of nuclei as well as the distribution of nucleoporins are strongly affected.
pronuclear nuclear appearance abnormal
C_elegans_phenotype_ontology
Pna
WBPhenotype:0001374
pronuclear nuclear appearance variant emb
The shape and size of nuclei as well as the distribution of nucleoporins are strongly affected.
WB:WBPaper00028895
WB:cab
The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection.
C_elegans_phenotype_ontology
WBPhenotype:0001375
transgene expression undetectable
The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection.
WB:WBPerson557
The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells.
C_elegans_phenotype_ontology
WBPhenotype:0001376
transgene expression undetectable cell specific
The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells.
WB:WBPerson557
Variations in the generation of foci that mark crossover recombination events, compared to control. These foci mark the boundary of asymmetric synaptonemal complex disassembly.
break induced focus formation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001377
break induced focus formation variant
Variations in the generation of foci that mark crossover recombination events, compared to control. These foci mark the boundary of asymmetric synaptonemal complex disassembly.
WB:WBPaper00032296
WB:WBPerson2021
WB:WBPerson557
Any variation in the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle compared to control animals.
mitotic chromosome segregation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001378
Possible XP.
mitotic chromosome segregation variant
Any variation in the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle compared to control animals.
GO:0000070
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals.
organism toxic chemical response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001379
organism toxic chemical response variant
Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals.
WB:WBPerson557
Animals respond to anoxic (trace oxygen levels) stress after a shorter exposure time compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001380
anoxia hypersensitive
Animals respond to anoxic (trace oxygen levels) stress after a shorter exposure time compared to control.
WB:WBPerson2021
Animals fail to respond to trace amounts of oxygen that elicit a response in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001381
anoxia resistant
Animals fail to respond to trace amounts of oxygen that elicit a response in control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications), compared to control. This includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
protein modification abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001382
protein modification variant
Variations in the covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications), compared to control. This includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
GO:0006464
WB:WBPerson2021
Variations in the processes that incorporate methyl groups to one or more amino acids within a protein, compared to control.
protein methylation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001383
protein methylation variant
Variations in the processes that incorporate methyl groups to one or more amino acids within a protein, compared to control.
GO:0006479
WB:WBPerson2021
Animals exhibit a reduction in the production of new individuals that contain some portion of their genetic material inherited from that organism as a result of defective gametes.
C_elegans_phenotype_ontology
WBPhenotype:0001384
fertility reduced
Animals exhibit a reduction in the production of new individuals that contain some portion of their genetic material inherited from that organism as a result of defective gametes.
GO:0000003
WB:WBPerson2021
WB:WBPerson557
Relatively unspecialized germ cells prematurely acquire the specialized properties of mature oocytes.
C_elegans_phenotype_ontology
WBPhenotype:0001385
precocious oogenesis
Relatively unspecialized germ cells prematurely acquire the specialized properties of mature oocytes.
WB:WBPaper00001475
WB:WBPaper00028819
WB:WBPerson2021
Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) in adult hermaphrodites during sexual reproduction.
C_elegans_phenotype_ontology
WBPhenotype:0001386
fertilization defective hermaphrodite
Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) in adult hermaphrodites during sexual reproduction.
WB:WBPerson2021
Failure of male-derived sperm to fuse with an oocyte during sexual reproduction.
C_elegans_phenotype_ontology
WBPhenotype:0001387
fertilization defect male
Failure of male-derived sperm to fuse with an oocyte during sexual reproduction.
WB:WBPaper00033007
WB:WBPerson2021
Organisms respond to a lower dosage of gamma rays or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001388
organism hypersensitive gamma irradiation
Organisms respond to a lower dosage of gamma rays or a shorter exposure compared to control animals.
WB:WBPerson557
Cells fail to respond to the dosage of gamma irradiation that elicits a response in control animals. Alternatively, cells require longer exposure times to gamma irradiation to mimic the response observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001389
cell gamma ray resistant
Cells fail to respond to the dosage of gamma irradiation that elicits a response in control animals. Alternatively, cells require longer exposure times to gamma irradiation to mimic the response observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Cells respond to a lower dosage of UV or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001390
cell UV hypersensitive
Cells respond to a lower dosage of UV or a shorter exposure compared to control animals.
WB:WBPerson557
Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001391
gamma ray induced apoptosis increased
Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control.
WB:WBPerson712
Cells of the animals cease during one of its replicative phases (G1, S, G2, M).
C_elegans_phenotype_ontology
WBPhenotype:0001392
cell cycle arrest
Cells of the animals cease during one of its replicative phases (G1, S, G2, M).
GO:0051726
WB:WBPerson557
WB:WBPerson712
Variations in the processes that reduce the internal pH of a cell (measured by the concentration of the hydrogen ion), compared to control.
cell acidification abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001393
cell acidification variant
Variations in the processes that reduce the internal pH of a cell (measured by the concentration of the hydrogen ion), compared to control.
GO:0045851
WB:WBPerson2021
Animals lack the capacity to reduce the internal pH of a cell.
C_elegans_phenotype_ontology
no pumping
WBPhenotype:0001394
cell acidification defective
Animals lack the capacity to reduce the internal pH of a cell.
GO:0045851
WB:WBPerson2021
Vacuoles accumulate in the body. A vacuole is a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.
C_elegans_phenotype_ontology
WBPhenotype:0001395
body vacuole
Vacuoles accumulate in the body. A vacuole is a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.
GO:0005776
WB:WBPerson557
Animals completely lack any pharyngeal pumping motion.
C_elegans_phenotype_ontology
WBPhenotype:0001396
pumping absent
Animals completely lack any pharyngeal pumping motion.
WB:WBPaper00001894
WB:WBPerson2021
Animals exhibit an increase in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001397
necrotic cell death increased
Animals exhibit an increase in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control.
GO:0070265
WB:WBPerson712
Animals display variations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in control animals.
neurite morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001398
neurite morphology variant
Animals display variations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in control animals.
GO:0043005
WB:WBPaper00028886
WB:WBPerson712
Any variation in the structure, form or composition of the semipermeable lipid bilayer that creates a boundary between the interior and exterior environment for cells, cellular organelles and tissues, within an organism compared to control.
cell membrane morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001399
cell membrane morphology variant
Any variation in the structure, form or composition of the semipermeable lipid bilayer that creates a boundary between the interior and exterior environment for cells, cellular organelles and tissues, within an organism compared to control.
GO:0005886
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the measured expression of a protein compared to that observed in control animals.
level of protein expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001400
level of protein expression variant
Animals exhibit variations in the measured expression of a protein compared to that observed in control animals.
WB:WBPerson2021
The morphological appearance of mitochondria is varied compared to control animals.
mitochondria morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001401
mitochondria morphology variant
The morphological appearance of mitochondria is varied compared to control animals.
WB:cab
Mitochondria are interconnected by thin tubules of mitochondrial inner or outer membrane.
connected mitochodria muscle
connected mitochondria epithelial
C_elegans_phenotype_ontology
WBPhenotype:0001402
connected mitochondria
Mitochondria are interconnected by thin tubules of mitochondrial inner or outer membrane.
GO:0007006
WB:WBPaper00032231
WB:WBPerson712
Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control.
antibody subcellular localization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001403
antibody subcellular localization variant
Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation that results in the detection of protein expression in cells/tissues through antibody staining, that is otherwise not observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001404
ectopic expression antibody
Any variation that results in the detection of protein expression in cells/tissues through antibody staining, that is otherwise not observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.
protein aggregation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001405
protein aggregation variant
Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.
WB:WBPaper00034765
WB:WBPerson2021
Variations that result in a decrease in protein expression in male animals compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001406
protein expression reduced male
Variations that result in a decrease in protein expression in male animals compared to that observed in control animals.
WB:WBPerson2021
Variations that result in a decrease in protein expression in specific cells compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001407
protein expression reduced cell specific
Variations that result in a decrease in protein expression in specific cells compared to that observed in control animals.
WB:WBPerson2021
Any variation in the cellular or subcellular distribution of a protein compared to that observed in control animals.
pattern protein expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001408
pattern protein expression variant
Any variation in the cellular or subcellular distribution of a protein compared to that observed in control animals.
WB:WBPerson2021
Any variation that results in the cellular expression of a protein in cells/tissues, that is otherwise not observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001409
protein expression ectopic
Any variation that results in the cellular expression of a protein in cells/tissues, that is otherwise not observed in control animals.
WB:WBPerson2021
Animals fail to express a given protein or class of proteins.
C_elegans_phenotype_ontology
WBPhenotype:0001410
protein expression absent
Animals fail to express a given protein or class of proteins.
WB:WBPerson2021
Animals exhibit an altered display of glycosylated proteins or lipids or altered access to glycosylated moieties along their surface from that observed in control animals of the same developmental stage. In C. elegans, variations in surface accessible glycosylated species are often revealed by altered lectin-binding from that observed in control animals.
Srf
cuticle carbohydrate surface abnormal
C_elegans_phenotype_ontology
ectopic lectin binding
WBPhenotype:0001411
cuticle carbohydrate surface variant
Animals exhibit an altered display of glycosylated proteins or lipids or altered access to glycosylated moieties along their surface from that observed in control animals of the same developmental stage. In C. elegans, variations in surface accessible glycosylated species are often revealed by altered lectin-binding from that observed in control animals.
WB:WBPaper00001576
WB:WBPerson712
Animals exhibit variations in the organization of the longitudinal ridges on the cuticle along the length of the animal, from that observed for control animals of the same developmental stage.
alae morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001412
alae morphology variant
Animals exhibit variations in the organization of the longitudinal ridges on the cuticle along the length of the animal, from that observed for control animals of the same developmental stage.
WB:WBPaper00000465
WB:WBPaper00031415
WB:WBPerson712
Animals do not exhibit tail-swelling in response to infection by a bacterial pathogen (such as Microbacterium nematophilum) compared to control.
Bus
C_elegans_phenotype_ontology
WBPhenotype:0001413
bacterially unswollen
Animals do not exhibit tail-swelling in response to infection by a bacterial pathogen (such as Microbacterium nematophilum) compared to control.
WB:WBPaper00026735
WB:cab
Males exhibit defects in the specific actions or reactions that are associated with reproduction.
Cod
C_elegans_phenotype_ontology
WBPhenotype:0001414
male mating defective
Males exhibit defects in the specific actions or reactions that are associated with reproduction.
GO:0060179
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations that result in variations in the ability of or extent to which pathogens adhere to the surface of animals, compared to control.
pathogen adherence abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001415
pathogen adherence variant
Animals exhibit variations that result in variations in the ability of or extent to which pathogens adhere to the surface of animals, compared to control.
WB:WBPaper00026735
WB:WBPerson2987
WB:cab
Pathogens are unable to adhere/colonize the surface of host animals. This defect is often associated with changes in cuticle surface properties of the host.
C_elegans_phenotype_ontology
WBPhenotype:0001416
pathogen adherence defect
Pathogens are unable to adhere/colonize the surface of host animals. This defect is often associated with changes in cuticle surface properties of the host.
WB:WBPaper00028877
WB:WBPerson2021
Any variation in the state or activity of an organism in response to extreme dryness or drought-like conditions, compared to control .
organism desication response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001417
organism desiccation response variant
Any variation in the state or activity of an organism in response to extreme dryness or drought-like conditions, compared to control .
GO:0009819
WB:WBPerson2021
Animals respond to less severe drought-like conditions or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001418
organism hypersensitive desiccation
Animals respond to less severe drought-like conditions or a shorter exposure compared to control animals.
WB:WBPerson2021
Animals respond to emetine at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001419
emetine hypersensitive
Animals respond to emetine at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth.
Bah
C_elegans_phenotype_ontology
WBPhenotype:0001420
biofilm absent head
Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth.
WB:WBPaper00005238
WB:cab
Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control.
endocytic transport abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001421
endocytic transport variant
Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control.
GO:0016197
WB:WBPaper00031894
WB:WBPerson712
Animals exhibit defects in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling.
C_elegans_phenotype_ontology
WBPhenotype:0001422
endocytic transport defect
Animals exhibit defects in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling.
GO:0016197
WB:WBPerson557
Animals exhibit variations in any physical or chemical process required for the coelomocyte to carry out its normal functions or activities, compared to control animals.
coelomocyte physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001423
coelomocyte physiology variant
Animals exhibit variations in any physical or chemical process required for the coelomocyte to carry out its normal functions or activities, compared to control animals.
GO:0009987
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the oocyte to carry out its normal functions or activities, compared to control animals.
oocyte physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001424
oocyte physiology variant
Animals exhibit variations in any physical or chemical process required for the oocyte to carry out its normal functions or activities, compared to control animals.
GO:0009987
WB:WBPerson557
WB:WBPerson712
Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes.
C_elegans_phenotype_ontology
Rme
WBPhenotype:0001425
Possible XP = GO:0006898.
receptor mediated endocytosis defective
Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes.
GO:0006898
WB:WBPerson2021
WB:cab
pmid:16042554
Fluid-phase endocytosis by coelomocytes is less frequent or efficient compared to control.
C_elegans_phenotype_ontology
Cup
WBPhenotype:0001426
coelomocyte endocytosis defective
Fluid-phase endocytosis by coelomocytes is less frequent or efficient compared to control.
WB:cab
pmid:16042554
Animals exhibit variations in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control animals.
cytoplasmic appearance abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001427
cytoplasmic appearance variant
Animals exhibit variations in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Vacuoles accumulate in the intestine.
C_elegans_phenotype_ontology
WBPhenotype:0001428
intestinal vacuole
Vacuoles accumulate in the intestine.
WB:WBPaper00004718
WB:WBPaper00031894
WB:WBPerson712
Animals accumulate an excess of vesicle-like structures in cells.
C_elegans_phenotype_ontology
WBPhenotype:0001429
granules cytoplasm
Animals accumulate an excess of vesicle-like structures in cells.
WB:cab
pmid:17203072
Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome, compared to control.
lysosome organization biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001430
Possible XP.
lysosome organization biogenesis variant
Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome, compared to control.
GO:0007040
WB:WBPerson2021
WB:WBPerson557
Male tails fail to undergo tip retraction thereby forming a 'leptoderan' or 'pointed' adult tail.
Lep
male tail spike
C_elegans_phenotype_ontology
leptoderan tail
WBPhenotype:0001431
pointed tail tip male
Male tails fail to undergo tip retraction thereby forming a 'leptoderan' or 'pointed' adult tail.
WB:WBPerson2021
WB:WBPerson557
Adult males exhibit a truncated tail, often without a fan or have well-developed fans but squarish, truncated back ends compared to control. In C. elegans this is due to precocious male tail tip retraction beginning in the early L3 stage (normally retraction begins in the L4 stage). Condition can be lethal if the function of the anus is affected.
Ore
C_elegans_phenotype_ontology
WBPhenotype:0001432
over retracted male tail
Adult males exhibit a truncated tail, often without a fan or have well-developed fans but squarish, truncated back ends compared to control. In C. elegans this is due to precocious male tail tip retraction beginning in the early L3 stage (normally retraction begins in the L4 stage). Condition can be lethal if the function of the anus is affected.
WB:cab
pmid:16806150
Two or more individual cells form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes at an earlier stage of development compared to comparable cells in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001433
precocious cell fusion
Two or more individual cells form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes at an earlier stage of development compared to comparable cells in control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific chemical concentration gradient compared to control. Directed movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
chemotaxis abnormal
C_elegans_phenotype_ontology
Che
WBPhenotype:0001434
chemotaxis variant
Any variation in the directed movement of a worm in response to a specific chemical concentration gradient compared to control. Directed movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0006935
WB:cab
Failure in directed movement in response to ammonium chloride compared to control. In C. elegans, NH4Cl is an attractant. NH4Cl has also subsequently been used to assay for Cl- attraction in C. elegans.
C_elegans_phenotype_ontology
chloride chemotaxis defective
WBPhenotype:0001435
ammonium chloride chemotaxis defective
Failure in directed movement in response to ammonium chloride compared to control. In C. elegans, NH4Cl is an attractant. NH4Cl has also subsequently been used to assay for Cl- attraction in C. elegans.
WB:WBPaper00002087
WB:WBPaper00004609
WB:WBPaper00026812
chloride chemotaxis defective
WB:WBPerson2021
Animals tend to initiate a response more often, compared to control, after nose-on collisions with an object. In C. elegans, animals initiate backwards movement in response to nose touch.
C_elegans_phenotype_ontology
WBPhenotype:0001436
nose touch hypersensitive
Animals tend to initiate a response more often, compared to control, after nose-on collisions with an object. In C. elegans, animals initiate backwards movement in response to nose touch.
WB:WBPaper00028963
WB:WBPerson557
Animals execute a response, via directed movement to octanol at a lower concentration or shorter exposure time compared to control. In C. elegans, animals avoid octanol.
C_elegans_phenotype_ontology
WBPhenotype:0001437
octanol chemotaxis hypersensitive
Animals execute a response, via directed movement to octanol at a lower concentration or shorter exposure time compared to control. In C. elegans, animals avoid octanol.
WB:WBPaper00028963
Animals fail to move towards attractive volatile organic molecules. In C. elegans, these compounds are sensed by the AWA and AWC neurons.
C_elegans_phenotype_ontology
WBPhenotype:0001438
odorant positive chemotaxis defective
Animals fail to move towards attractive volatile organic molecules. In C. elegans, these compounds are sensed by the AWA and AWC neurons.
WB:WBPerson2021
Animals fail to move towards attractive anions.
C_elegans_phenotype_ontology
WBPhenotype:0001439
anion positive chemotaxis defective
Animals fail to move towards attractive anions.
WB:WBPaper00002033
WB:WBPaper00028386
Animals fail to move towards attractive cations.
C_elegans_phenotype_ontology
WBPhenotype:0001440
cation positive chemotaxis defective
Animals fail to move towards attractive cations.
WB:WBPaper00004609
Animals fail to move towards attractive water-soluble chemicals.
C_elegans_phenotype_ontology
water soluble positive chemotaxis abnormal
WBPhenotype:0001441
aqueous positive chemotaxis defective
Animals fail to move towards attractive water-soluble chemicals.
WB:WBPerson2021
Failure in directed movement in response to sodium acetate. In C. elegans, sodium acetate is an attractant. Sodium acetate has also subsequently been used to assay for Na+ attraction in C. elegans.
C_elegans_phenotype_ontology
sodium chemotaxis defective
WBPhenotype:0001442
sodium acetate chemotaxis defective
Failure in directed movement in response to sodium acetate. In C. elegans, sodium acetate is an attractant. Sodium acetate has also subsequently been used to assay for Na+ attraction in C. elegans.
WB:WBPaper00000650
WB:WBPaper00004609
WB:WBPaper00006394
sodium chemotaxis defective
WB:WBPerson2021
Animals exhibit variations in response to water-soluble chemicals, compared to control.
aqueous chemosensory response abnormal
C_elegans_phenotype_ontology
water soluble chemosensory response abnormal
WBPhenotype:0001443
aqueous chemosensory response variant
Animals exhibit variations in response to water-soluble chemicals, compared to control.
WB:cab
Animals do not exhibit characteristic desensitization to a water-soluble chemo-attractive signal in a time-concentration dependent and reversible manner compared to control.
aqueous adaptation abnormal
C_elegans_phenotype_ontology
gustatory plasticity abnormal
water soluble adaptation abnormal
WBPhenotype:0001444
aqueous adaptation defective
Animals do not exhibit characteristic desensitization to a water-soluble chemo-attractive signal in a time-concentration dependent and reversible manner compared to control.
WB:cab
WB:cgc5150
Animals do not exhibit characteristic chemoattractive desensitization to sodium acetate in a time-concentration dependent and reversible manner compared to control.
sodium acetate adaptation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001445
sodium acetate adaptation defective
Animals do not exhibit characteristic chemoattractive desensitization to sodium acetate in a time-concentration dependent and reversible manner compared to control.
WB:cab
WB:cgc5150
Animals do not exhibit characteristic chemoattractive desensitization to sodium chloride in a time-concentration dependent and reversible manner compared to control.
sodium chloride adaptation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001446
sodium chloride adaptation defective
Animals do not exhibit characteristic chemoattractive desensitization to sodium chloride in a time-concentration dependent and reversible manner compared to control.
WB:cab
WB:cgc5150
Animals do not exhibit characteristic chemoattractive desensitization to ammonium chloride in a time-concentration dependent and reversible manner compared to control.
ammonium chloride adaptation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001447
ammonium chloride adaptation defective
Animals do not exhibit characteristic chemoattractive desensitization to ammonium chloride in a time-concentration dependent and reversible manner compared to control.
WB:cab
WB:cgc5150
Animals fail to move away from repellant volatile organic chemicals.
C_elegans_phenotype_ontology
volatile negative chemotaxis defective
WBPhenotype:0001448
odorant negative chemotaxis defective
Animals fail to move away from repellant volatile organic chemicals.
WB:WBPerson2021
Animals fail to move away from repellent water soluble chemicals.
C_elegans_phenotype_ontology
water soluble chemotaxis defective
WBPhenotype:0001449
aqueous negative chemotaxis defective
Animals fail to move away from repellent water soluble chemicals.
WB:WBPerson2021
Animals exhibit variations through directed movement, in response to repellant water soluble chemicals, compared to control.
aqueous negative chemotaxis abnormal
C_elegans_phenotype_ontology
water soluble chemotaxis abnormal
WBPhenotype:0001450
aqueous negative chemotaxis variant
Animals exhibit variations through directed movement, in response to repellant water soluble chemicals, compared to control.
WB:WBPaper00006481
Any variation in the directed movement of a worm in response to a specific concentration gradient of garlic compared to control. In C. elegans, garlic is typically a repellant.
garlic chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001451
garlic chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of garlic compared to control. In C. elegans, garlic is typically a repellant.
WB:WBPaper00002135
WB:WBPaper00006481
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of octanol. In C. elegans, octanol is typically a repellant.
octanol chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001452
octanol chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of octanol. In C. elegans, octanol is typically a repellant.
WB:WBPerson557
Animals exhibit variations in their avoidance response to high concentrations of sodium chloride solution compared to control.
high sodium chloride concentration osmotic avoidance abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001453
high sodium chloride concentration osmotic avoidance variant
Animals exhibit variations in their avoidance response to high concentrations of sodium chloride solution compared to control.
WB:WBPerson2021
Any variation in the directed movement of a worm in response to a specific concentration gradient of the bitter tastant quinine, a water soluble molecule. In C. elegans, quinine is typically a repellant.
quinine chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001454
quinine chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of the bitter tastant quinine, a water soluble molecule. In C. elegans, quinine is typically a repellant.
WB:WBPaper00002135
WB:WBPaper00027118
WB:WBPaper00035961
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations through directed movement, in response to repellant volatile organic chemicals, compared to control.
odorant negative chemotaxis abnormal
C_elegans_phenotype_ontology
volatile negative chemotaxis abnormal
WBPhenotype:0001455
odorant negative chemotaxis variant
Animals exhibit variations through directed movement, in response to repellant volatile organic chemicals, compared to control.
WB:WBPaper00001786
Any variation in the directed movement of a worm in response to a specific concentration gradient of nonanone. In C. elegans, nonanone is typically a repellant.
nonanone chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001456
nonanone chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of nonanone. In C. elegans, nonanone is typically a repellant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of bromide. In C. elegans, bromide is typically an attractant.
bromide chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001457
bromide chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of bromide. In C. elegans, bromide is typically an attractant.
WB:WBPaper00000387
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of chloride.
chloride chemotaxis abnormal
C_elegans_phenotype_ontology
ammonium chloride chemotaxis abnormal
WBPhenotype:0001458
chloride chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of chloride.
WB:WBPaper00000387
ammonium chloride chemotaxis abnormal
WB:WBPerson2021
Any variation in the directed movement of a worm in response to a specific concentration gradient of iodide.
iodide chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001459
iodide chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of iodide.
WB:WBPaper00000387
Any variation in the directed movement of a worm in response to a specific concentration gradient of ammonium chloride. In C. elegans, at specific concentrations, ammonium chloride is an attractant. NH4Cl has also been used to assay for Cl- attraction.
ammonium chloride chemotaxis abnormal
C_elegans_phenotype_ontology
chloride chemotaxis abnormal
WBPhenotype:0001460
ammonium chloride chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of ammonium chloride. In C. elegans, at specific concentrations, ammonium chloride is an attractant. NH4Cl has also been used to assay for Cl- attraction.
WB:WBPaper00000387
WB:WBPaper00004609
WB:WBPaper00026812
chloride chemotaxis abnormal
WB:WBPerson2021
Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium acetate. In C. elegans, at specific concentrations, sodium acetate is an attractant. Sodium acetate has also been used to assay for Na+ attraction.
sodium acetate chemotaxis abnormal
C_elegans_phenotype_ontology
sodium chemotaxis abnormal
WBPhenotype:0001461
sodium acetate chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium acetate. In C. elegans, at specific concentrations, sodium acetate is an attractant. Sodium acetate has also been used to assay for Na+ attraction.
WB:WBPaper00000387
WB:WBPaper00000650
WB:WBPaper00004609)
sodium chemotaxis abnormal
WB:WBPerson2021
Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium chloride. In C. elegans, at specific concentrations, sodium chloride is an attractant.
sodium chloride chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001462
sodium chloride chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium chloride. In C. elegans, at specific concentrations, sodium chloride is an attractant.
WB:WBPaper00000387
Any variation in the directed movement of a worm in response to a specific concentration gradient of cAMP.
cAMP chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001463
cAMP chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of cAMP.
GO:0043327
WB:WBPaper00000387
Any variation in the directed movement of a worm in response to a specific concentration gradient of cGMP.
cGMP chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001464
cGMP chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of cGMP.
WB:WBPaper00000387
Any variation in the directed movement of a worm in response to a specific concentration gradient of acetone. In C. elegans, at specific concentrations, acetone is an attractant.
acetone chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001465
acetone chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of acetone. In C. elegans, at specific concentrations, acetone is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWA sensory neuron in control animals.
AWA odorant chemotaxis abnormal
C_elegans_phenotype_ontology
AWA volatile chemotaxis abnormal
WBPhenotype:0001466
AWA odorant chemotaxis variant
Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWA sensory neuron in control animals.
WB:WBPerson2021
Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWC sensory neuron in control animals.
AWC odorant chemotaxis abnormal
C_elegans_phenotype_ontology
AWC volatile chemotaxis abnormal
WBPhenotype:0001467
AWC odorant chemotaxis variant
Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWC sensory neuron in control animals.
WB:WBPerson2021
Any variation in the directed movement of a worm in response to a specific concentration gradient of benzaldehyde. In C. elegans, at specific concentrations, benzaldehyde is an attractant.
benzaldehyde chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001468
benzaldehyde chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of benzaldehyde. In C. elegans, at specific concentrations, benzaldehyde is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of butanone. In C. elegans, at specific concentrations, butanone is an attractant.
butanone chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001469
butanone chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of butanone. In C. elegans, at specific concentrations, butanone is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of diacetyl. In C. elegans, at specific concentrations, diacetyl is an attractant.
diacetyl chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001470
diacetyl chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of diacetyl. In C. elegans, at specific concentrations, diacetyl is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of hexanol. In C. elegans, at specific concentrations, hexanol is an attractant.
hexanol chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001471
hexanol chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of hexanol. In C. elegans, at specific concentrations, hexanol is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of isoamyl alcohol. In C. elegans, at specific concentrations, isoamyl alcohol is an attractant.
isoamyl alcohol chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001472
isoamyl alcohol chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of isoamyl alcohol. In C. elegans, at specific concentrations, isoamyl alcohol is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanol. In C. elegans, at specific concentrations, pentanol is an attractant.
pentanol chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001473
pentanol chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanol. In C. elegans, at specific concentrations, pentanol is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of pyrazine. In C. elegans, at specific concentrations, pyrazine is an attractant.
pyrazine chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001474
pyrazine chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of pyrazine. In C. elegans, at specific concentrations, pyrazine is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of trimethylthiazole. In C. elegans, at specific concentrations, trimethylthiazole is an attractant.
trimethylthiazole chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001475
trimethylthiazole chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of trimethylthiazole. In C. elegans, at specific concentrations, trimethylthiazole is an attractant.
WB:WBPerson2021
WB:WBPerson557
Any variation in the defecation motor program that involves the contraction of the anterior body wall muscles compared to control.
anterior body contraction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001476
anterior body contraction variant
Any variation in the defecation motor program that involves the contraction of the anterior body wall muscles compared to control.
WB:WBPaper00001937
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons, compared to control.
anterograde transport abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001477
anterograde transport variant
Any variation in the directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons, compared to control.
GO:0008089
WB:WBPerson2021
WB:WBPerson557
Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
body elongation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001478
body elongation variant
Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that induces dauer formation in control animals.
dauer pheromone sensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001479
dauer pheromone sensation variant
Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that induces dauer formation in control animals.
GO:0043695
WB:WBPerson2021
WB:WBPerson557
Variations in the rhythmic relaxations of the a highly specialized cuticle region of the pharynx inside the lumen of the second bulb, compared to control (Wormatlas).
grinder relaxation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001480
grinder relaxation variant
Variations in the rhythmic relaxations of the a highly specialized cuticle region of the pharynx inside the lumen of the second bulb, compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The number of body thrashes within an aqueous environment in a given period of time is increased, compared with control worms.
C_elegans_phenotype_ontology
WBPhenotype:0001481
thrashing increased
The number of body thrashes within an aqueous environment in a given period of time is increased, compared with control worms.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit a reduction in the frequency of oscillations between adjacent body segments from that observed for control animals.
WBPhenotype:0002330
bending frequency reduced
frequency of sinusoidal movement reduced
temporal frequency of sinusoidal movement decreased
C_elegans_phenotype_ontology
WBPhenotype:0001482
frequency body bend reduced
Animals exhibit a reduction in the frequency of oscillations between adjacent body segments from that observed for control animals.
WB:WBPaper00024949
WB:WBPerson557
WB:WBPerson712
The eggs being deposited by adults are of a later developmental stage, compared to control. In C. elegans, this is likely to be a consequence of delayed active egg-laying periods.
C_elegans_phenotype_ontology
WBPhenotype:0001483
late stage egg laid
The eggs being deposited by adults are of a later developmental stage, compared to control. In C. elegans, this is likely to be a consequence of delayed active egg-laying periods.
WB:WBPaper00004310
WB:WBPerson2021
Animals fail to execute directed movement in response to ammonium acetate. In C. elegans, ammonium acetate is an attractant.
C_elegans_phenotype_ontology
WBPhenotype:0001484
ammonium acetate chemotaxis defective
Animals fail to execute directed movement in response to ammonium acetate. In C. elegans, ammonium acetate is an attractant.
WB:WBPaper00004136
Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control.
ER stress response abnormal
endoplasmic reticulum stress response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001485
ER stress response variant
Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control.
GO:0030968
Animals accumulate unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria.
C_elegans_phenotype_ontology
WBPhenotype:0001486
unfolded protein accumulation
Animals accumulate unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria.
WB:WBPerson557
Animals exhibit variations in the development of the male elongated sclerotized structures covered by a hardened layer of cuticle in the tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control.
male spicule development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001487
male spicule development variant
Animals exhibit variations in the development of the male elongated sclerotized structures covered by a hardened layer of cuticle in the tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control.
WB:WBPerson363
WB:cab
Animals exhibit variations in the development of the sclerotic cuticle that forms the roof of the proctodeum (gubernaculum) compared to control.
gubernaculum development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001488
gubernaculum development variant
Animals exhibit variations in the development of the sclerotic cuticle that forms the roof of the proctodeum (gubernaculum) compared to control.
WB:WBPerson363
WB:cab
Animals exhibit variations in the structure or composition of the sclerotic cuticle that forms the roof of the proctodeum, from that observed in control animals.
gubernaculum morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001489
gubernaculum morphology variant
Animals exhibit variations in the structure or composition of the sclerotic cuticle that forms the roof of the proctodeum, from that observed in control animals.
WB:WBPaper00027278
WB:WBPerson363
WB:WBPerson712
WB:cab
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0001490
obsolete posterior region morphology abnormal
true
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0001491
obsolete anterior region morphology abnormal
true
Animals lack a properly developed posterior region compared to control. In C. elegans, mutants exhibit a severely deformed posterior region with a variable knob-like shape; accompanied by arrest at about the time of hatching with fairly normal pharyngeal and anterior development. Most mutants arrest as L1 larvae, and 5% do not hatch.
Nob
C_elegans_phenotype_ontology
WBPhenotype:0001492
no back end
Animals lack a properly developed posterior region compared to control. In C. elegans, mutants exhibit a severely deformed posterior region with a variable knob-like shape; accompanied by arrest at about the time of hatching with fairly normal pharyngeal and anterior development. Most mutants arrest as L1 larvae, and 5% do not hatch.
WB:cab
WB:cgc4499
VPCs (vulval precursor cells) divide at an earlier stage of development compared to control animals; in C. elegans, VPCs divide in the mid-L3 stage to generate the 22 cells that comprise the vulva.
C_elegans_phenotype_ontology
WBPhenotype:0001493
VPC cell division precocious
VPCs (vulval precursor cells) divide at an earlier stage of development compared to control animals; in C. elegans, VPCs divide in the mid-L3 stage to generate the 22 cells that comprise the vulva.
WB:cab
pmid:16300753
DTCs migrate at an earlier stage of development, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001494
distal tip cell migration precocious
DTCs migrate at an earlier stage of development, compared to control.
WB:cab
pmid:16300753
Cells divide at an earlier stage of development compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001495
cell division precocious
Cells divide at an earlier stage of development compared to control animals.
WB:cab
Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle.
WBPhenotype:0001214
metaphase to anaphase transition fails
C_elegans_phenotype_ontology
Mat
WBPhenotype:0001496
metaphase to anaphase transition defect
Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle.
GO:0007091
WB:WBPerson712
Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids separate and migrate towards the poles of the spindle.
C_elegans_phenotype_ontology
WBPhenotype:0001497
mitotic metaphase to anaphase transition defect
Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids separate and migrate towards the poles of the spindle.
GO:0007091
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the pseudopod of the sperm to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
sperm pseudopod physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001498
sperm pseudopod physiology variant
Animals exhibit variations in any physical or chemical process required for the pseudopod of the sperm to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WB:WBPerson557
Variations in the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle, compared to control.
meiotic chromosome segregation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001499
Possible XP.
meiotic chromosome segregation variant
Variations in the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle, compared to control.
GO:0045132
WB:WBPerson2021
WB:WBPerson557
Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanedione.
pentanedione chemotaxis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001500
pentanedione chemotaxis variant
Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanedione.
WB:cab
WB:cgc2931
Animals fail to discriminate between distinct odorants.
odorant discrimination abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001501
odorant discrimination defective
Animals fail to discriminate between distinct odorants.
WB:cab
Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001502
chemical resistant
Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Any variation in the mechanisms used to ensure that axons in the ventral nerve cord maintain their correct positioning after termination of axonal outgrowth and target recognition compared to control.
ventral nerve cord maintenance abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001503
ventral nerve cord maintenance variant
Any variation in the mechanisms used to ensure that axons in the ventral nerve cord maintain their correct positioning after termination of axonal outgrowth and target recognition compared to control.
WB:WBPaper00005064
WB:WBPerson557
Sterility caused by aberrant maternal components required for normal postembryonic development and/or function of the germ line.
Mes
C_elegans_phenotype_ontology
WBPhenotype:0001504
maternal effect sterile
Sterility caused by aberrant maternal components required for normal postembryonic development and/or function of the germ line.
WB:WBPaper00001477
Any variation in the processes that govern spontaneous backward locomotion compared to control.
spontaneous reversal abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001505
spontaneous reversal variant
Any variation in the processes that govern spontaneous backward locomotion compared to control.
WB:WBPaper00001311
WB:WBPerson557
Any variation in the processes that govern the rate at which spontaneous backward locomotion is initiated compared to control.
spontaneous reversal rate abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001506
spontaneous reversal rate variant
Any variation in the processes that govern the rate at which spontaneous backward locomotion is initiated compared to control.
WB:WBPaper00001311
WB:WBPaper00026650
WB:WBPerson557
Animals fail to be affected by toxins produced by Bacillus thuringiensis (Bt toxins) in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001507
Bacillus thuringiensis toxin resistant
Animals fail to be affected by toxins produced by Bacillus thuringiensis (Bt toxins) in the same manner as control animals.
GO:0009410
WB:WBPaper00004264
WB:WBPaper00004776
WB:WBPerson557
Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such variations result in the loss of uterine-vulval connectivity and continuity.
anchor cell fusion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001508
anchor cell fusion defective
Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such variations result in the loss of uterine-vulval connectivity and continuity.
WB:WBPaper00029363
WB:WBPerson2021
Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are absent.
WBPhenotype:0000407
ray loss
C_elegans_phenotype_ontology
WBPhenotype:0001509
rays missing
Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are absent.
WB:WBPerson2021
WB:WBPerson557
Any variation in the processes that govern acquisition of neuronal cell fates compared to control.
neuronal cell fate specification abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001510
neuronal cell fate specification variant
Any variation in the processes that govern acquisition of neuronal cell fates compared to control.
WB:WBPerson2021
Variations in the stereotypical migration pattern of the linker cell in a developing male compared to control.
linker cell migration abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001511
linker cell migration variant
Variations in the stereotypical migration pattern of the linker cell in a developing male compared to control.
WB:WBPaper00028966
WB:WBPerson2021
Bilaterally symmetric cell fail to acquire specific left-right asymmetric properties such as L/R specific cell position, cell death or gene expression.
Lsy
C_elegans_phenotype_ontology
WBPhenotype:0001512
loss of left right asymmetry
Bilaterally symmetric cell fail to acquire specific left-right asymmetric properties such as L/R specific cell position, cell death or gene expression.
WB:WBPaper00037739
WB:WBPerson2021
Variations in the process of secretion of a class of membrane-bound vesicles found inside neurons, gland cells, and some epithelial cells in which the central core appears darkly stained when viewed in thin section by electron microscopy, compared to control. Exocytosis occurs via the fusion of the vesicle with the plasma membrane of a cell (Wormatlas).
dense core vesicle exocytosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001513
dense core vesicle exocytosis variant
Variations in the process of secretion of a class of membrane-bound vesicles found inside neurons, gland cells, and some epithelial cells in which the central core appears darkly stained when viewed in thin section by electron microscopy, compared to control. Exocytosis occurs via the fusion of the vesicle with the plasma membrane of a cell (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas).
synaptic vesicle endocytosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001514
synaptic vesicle endocytosis variant
Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the quantity or patterning of electron-dense columnar structures that join the basal and cortical cuticle layers, from that observed in control animals.
struts abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001515
struts variant
Animals exhibit variations in the quantity or patterning of electron-dense columnar structures that join the basal and cortical cuticle layers, from that observed in control animals.
WB:WBPaper00000465
WB:WBPerson712
Animals exhibit a helically twisted cuticle. In practice the degree of twisting is measured as the number of helical twists the alae make about anterior/posterior axis of the animal.
cuticle helicity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001516
helical cuticle
Animals exhibit a helically twisted cuticle. In practice the degree of twisting is measured as the number of helical twists the alae make about anterior/posterior axis of the animal.
WB:WBPaper00000465
WB:WBPerson712
Animals exhibit variations in the circumferential pattern of ridges in the outer cortical layer of the cuticle, compared to that observed in control animals of the same developmental stage.
annulae morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001517
annulae morphology variant
Animals exhibit variations in the circumferential pattern of ridges in the outer cortical layer of the cuticle, compared to that observed in control animals of the same developmental stage.
WB:WBPaper00000465
WB:WBPaper00031415
WB:WBPerson712
Any variation in the levels and/or localization of biogenic amines compared to control animals.
FIF
biogenic amine physiology abnormal
C_elegans_phenotype_ontology
Formaldehyde induced fluorescence abnormal
WBPhenotype:0001518
biogenic amine physiology variant
Any variation in the levels and/or localization of biogenic amines compared to control animals.
WB:WBPaper00000365
Any variation in the orderly movement of cells along the posterior axis of the animal (abolished, misdirected or incomplete) compared to control.
abnormal posterior cell migration
C_elegans_phenotype_ontology
WBPhenotype:0001519
posterior cell migration variant
Any variation in the orderly movement of cells along the posterior axis of the animal (abolished, misdirected or incomplete) compared to control.
WB:WBPerson2021
Any variation in the orderly movement of neurons along the posterior axis of the animal(abolished, misdirected or incomplete) compared to control.
abnormal posterior neuron migration
C_elegans_phenotype_ontology
WBPhenotype:0001520
posterior neuron migration variant
Any variation in the orderly movement of neurons along the posterior axis of the animal(abolished, misdirected or incomplete) compared to control.
WB:WBPerson2021
Embryos retract after the embryonic elongation process.
C_elegans_phenotype_ontology
WBPhenotype:0001521
body elongation retracted
Embryos retract after the embryonic elongation process.
WB:WBPerson557
The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) constitutively extend into the external environment through the cloacal opening. In C. elegans males there are two copulatory spicules.
C_elegans_phenotype_ontology
WBPhenotype:0001522
spicules protrude
The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) constitutively extend into the external environment through the cloacal opening. In C. elegans males there are two copulatory spicules.
WB:WBPerson2021
WB:WBPerson557
Any variation in the makeup, density or area of the ECM compared to control.
extracellular matrix abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001523
extracellular matrix variant
Any variation in the makeup, density or area of the ECM compared to control.
WB:WBPerson712
Exhibition of quiescent behavior under inappropriate conditions and improper recovery from quiescent state. Quiescent behavior is normally coupled with lethargus.
quiescence abnormal
C_elegans_phenotype_ontology
narcoleptic
WBPhenotype:0001524
quiescence variant
Exhibition of quiescent behavior under inappropriate conditions and improper recovery from quiescent state. Quiescent behavior is normally coupled with lethargus.
WB:WBPerson2021
Animals exhibit variations in the structure or organization of the posterior region of the pharynx compared to control.
terminal bulb morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001525
terminal bulb morphology variant
Animals exhibit variations in the structure or organization of the posterior region of the pharynx compared to control.
WB:WBPerson2021
Animals exhibit variations in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that compared to control animals. In C. elegans, these specialized cells are characterized as having axoneme containing dendritic projections emanating from their cell body.
ciliated neuron morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001526
WBbt:0006816.
ciliated neuron morphology variant
Animals exhibit variations in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that compared to control animals. In C. elegans, these specialized cells are characterized as having axoneme containing dendritic projections emanating from their cell body.
WB:WBPaper00000503
WB:WBPaper00029016
WB:WBPerson712
Animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head or along the tail, compared to that observed in control animals.
amphid phasmid sensillum morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001527
WBbt:0005391.
amphid phasmid sensillum morphology variant
Animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head or along the tail, compared to that observed in control animals.
WB:WBPerson712
Animals exhibit variations in the quantity, structure or organization of any component of the sensillum channel including the sheath and or socket cells, their junctions with each other, channel neurons or surrounding epithelia compared to control.
sensillum accessory cell morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001528
sensillum accessory cell morphology variant
Animals exhibit variations in the quantity, structure or organization of any component of the sensillum channel including the sheath and or socket cells, their junctions with each other, channel neurons or surrounding epithelia compared to control.
WB:WBPaper00000932
WB:WBPerson712
OBSOLETE: Any variation in the form, structure or composition of an interfacial epithelial cell which forms a specialized environment surrounding the ciliated sensory ending(s) of one or more neurons and is often accompanied by a more distal socket cell compared to control (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0001529
obsolete sensilium sheath cell variant
true
OBSOLETE: Any variation in the form, structure or composition of an interfacial epithelial cell which forms a specialized environment surrounding the ciliated sensory ending(s) of one or more neurons and is often accompanied by a more distal socket cell compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake.
cephalic sensillum morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001530
WBbt:0006920.
cephalic sensillum morphology variant
Animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake.
WB:WBPaper00000214
WB:WBPaper00000503
WB:WBPaper00000932
WB:WBPerson712
Animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth.
labial sensillum morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001531
labial sensillum morphology variant
Animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth.
WB:WBPaper00000214
WB:WBPaper00000938
WB:WBPerson712
Animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2.
inner labial morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001532
inner labial morphology variant
Animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2.
WB:WBPaper00000938
WB:WBPerson712
Animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum.
outer labial morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001533
outer labial morphology variant
Animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum.
WB:WBPaper00000938
WB:WBPerson712
Any variation in makeup, density or area of the ECM lending structure to neurons compared to control animals. In C. elegans, the neuronal ECM is sometimes referred to as a mantle.
neuronal ECM abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001534
neuronal ECM variant
Any variation in makeup, density or area of the ECM lending structure to neurons compared to control animals. In C. elegans, the neuronal ECM is sometimes referred to as a mantle.
WB:WBPaper00000502
WB:WBPerson712
Animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC.
deirid sensillum morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001535
deirid sensillum morphology variant
Animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC.
WB:WBPaper00000938
WB:WBPaper00029016
WB:WBPerson712
Embryos exhibit variations in the patterning of differentiated cell types, compared to control.
embryonic cell patterning abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001536
embryonic cell patterning variant
Embryos exhibit variations in the patterning of differentiated cell types, compared to control.
WB:WBPerson557
Any variation in the ability of cells to monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated compared to control.
mRNA turnover abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001537
mRNA surveillance variant
Any variation in the ability of cells to monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated compared to control.
WB:WBPaper00004926
Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.
Smg
C_elegans_phenotype_ontology
WBPhenotype:0001538
mRNA surveillance defective
Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.
WB:WBPaper00001192
WB:WBPaper00004926
Animals exhibit variations in the entry into the dauer stage when exposed to conditions that induce dauer formation in control animals.
dauer induction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001539
dauer induction variant
Animals exhibit variations in the entry into the dauer stage when exposed to conditions that induce dauer formation in control animals.
WB:WBPerson2021
WB:WBPerson557
The life span of dauer-staged animals is either longer or shorter than that observed in control dauer animals.
dauer lifespan abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001540
dauer lifespan variant
The life span of dauer-staged animals is either longer or shorter than that observed in control dauer animals.
WB:WBPerson2021
Variations in the execution of the developmentally-regulated cell cycle arrest in the gonad during the dauer stage, compared to control.
dauer gonad arrest abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001541
dauer gonad arrest variant
Variations in the execution of the developmentally-regulated cell cycle arrest in the gonad during the dauer stage, compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the inhibition of feeding which is induced/occurs during the dauer stage compared to control.
dauer feeding suppressed abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001542
dauer feeding suppressed variant
Any variation in the inhibition of feeding which is induced/occurs during the dauer stage compared to control.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit a decrease in self-propelled movement on a solid medium compared to control animals.
dauer reduced locomotion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001543
dauer reduced locomotion variant
Dauer stage animals exhibit a decrease in self-propelled movement on a solid medium compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations in the state or activity of a dauer stage organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus, compared to control.
dauer sensory response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001544
dauer sensory response variant
Variations in the state or activity of a dauer stage organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus, compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the overall structure or appearance of an animal progressing through an alternative larval stage in response to environmental stresses compared to control animals.
dauer body morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001545
dauer body morphology variant
Any variation in the overall structure or appearance of an animal progressing through an alternative larval stage in response to environmental stresses compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations which lead to the decreased ability of dauer larva to survive at extreme conditions, such as high or low temperatures, the presence of dilute acids, detergents, anesthetics, or even fixatives, compared to control (Wormatlas).
dauer resistance to harsh conditions abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001546
dauer resistance to harsh conditions variant
Variations which lead to the decreased ability of dauer larva to survive at extreme conditions, such as high or low temperatures, the presence of dilute acids, detergents, anesthetics, or even fixatives, compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the chemical reactions and pathways that occur during the dauer life stage, compared to control.
dauer metabolism abnormal
dauer metabolism variant
C_elegans_phenotype_ontology
WBPhenotype:0001547
dauer metabolism phenotype
Animals exhibit variations in the chemical reactions and pathways that occur during the dauer life stage, compared to control.
WB:WBPerson2021
Any variation in the ratio of the body length to body width in a dauer stage animal, compared to control. Long thin animals will have a high axial ratio.
dauer axial ratio abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001548
dauer axial ratio variant
Any variation in the ratio of the body length to body width in a dauer stage animal, compared to control. Long thin animals will have a high axial ratio.
WB:WBPerson557
Dauer stage animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion.
dauer gut abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001549
dauer gut variant
Dauer stage animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion.
WB:WBPerson2021
WB:WBPerson557
Variations in the form or composition of the cuticle-lined lumenal region which lies just behind the lips at the entrance to the pharyngeal lumen in dauer stage animals compared to control (Wormatlas).
dauer buccal cavity morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001550
dauer buccal cavity morphology variant
Variations in the form or composition of the cuticle-lined lumenal region which lies just behind the lips at the entrance to the pharyngeal lumen in dauer stage animals compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) during the dauer larva stage, compared to control animals (Wormatlas). The dauer larval stage is a developmentally arrested larval stage that is specialized for survival under harsh, or otherwise unfavorable environmental conditions.
dauer cuticle abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001551
dauer cuticle variant
Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) during the dauer larva stage, compared to control animals (Wormatlas). The dauer larval stage is a developmentally arrested larval stage that is specialized for survival under harsh, or otherwise unfavorable environmental conditions.
WB:WBPerson2021
WB:WBPerson557
Variations in the form or composition of the mouthparts at the anterior end of the digestive tract during the dauer stage, compared to control.
dauer pharynx morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001552
dauer pharynx morphology variant
Variations in the form or composition of the mouthparts at the anterior end of the digestive tract during the dauer stage, compared to control.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas).
dauer excretory gland abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001553
dauer excretory gland variant
Dauer stage animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control.
dauer nose morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001554
dauer nose morphology variant
Dauer stage animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the dauer sensory system, compared to control. The dauer sensory system is used to perceive the physical and chemical environment during the dauer larval stage.
dauer sensory system morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001555
dauer sensory system morphology variant
Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the dauer sensory system, compared to control. The dauer sensory system is used to perceive the physical and chemical environment during the dauer larval stage.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals.
dauer sensillum abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001556
dauer sensillum variant
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth.
dauer labial sensillum abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001557
dauer labial sensillum variant
Dauer stage animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head, compared to that observed in control animals.
dauer amphid sensillum abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001558
dauer amphid sensillum variant
Dauer stage animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head, compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC.
dauer deirid sensillum abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001559
dauer deirid sensillum variant
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
dauer sensory system plug abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001560
obsolete dauer sensory system plug variant
true
OBSOLETE.
WB:WBPerson557
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2.
dauer inner labial sensillum abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001561
dauer inner labial sensillum variant
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum.
dauer outer labial sensillum abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001562
dauer outer labial sensillum variant
Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum.
WB:WBPerson2021
WB:WBPerson557
Dauer stage animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake.
dauer cephalic sensillum abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001563
dauer cephalic sensillum variant
Dauer stage animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake.
WB:WBPerson2021
WB:WBPerson557
The window of production of self-fertilized eggs exceeds or does not extend to the same length as control.
duration of self fertility abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001564
duration of self fertility variant
The window of production of self-fertilized eggs exceeds or does not extend to the same length as control.
WB:WBPaper00002419
WB:WBPerson712
Failure to execute characteristic response to lysine as defined by control animals. In C. elegans, lysine is an attractant.
C_elegans_phenotype_ontology
WBPhenotype:0001565
lysine chemotaxis defective
Failure to execute characteristic response to lysine as defined by control animals. In C. elegans, lysine is an attractant.
WB:WBPaper00001481
WB:WBPaper00001786
WB:WBPerson2021
Any variation in the process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos compared to control.
ventral enclosure abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001566
ventral enclosure variant
Any variation in the process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos compared to control.
WB:WBPaper00027244
WB:WBPerson2021
Nuclei of specific cells are larger compared to control animals.
nuclear size increased
C_elegans_phenotype_ontology
WBPhenotype:0001567
nuclei enlarged
Nuclei of specific cells are larger compared to control animals.
WB:WBPerson557
Any variation in the export of mRNA from the cell nucleus compared to control.
mRNA export abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001568
mRNA export variant
Any variation in the export of mRNA from the cell nucleus compared to control.
WB:WBPaper00005960
The characteristic organization of myosin filaments into discrete A-bands within the muscle cells is disrupted. In C. elegans, myosin filaments no longer appear as continuous longitudinally oriented fibers across the muscle quadrants.
body wall muscle myosin organization abnormal
C_elegans_phenotype_ontology
Dim
body wall muscle thick myofilament organization abnormal
WBPhenotype:0001569
body wall muscle myosin organization defective
The characteristic organization of myosin filaments into discrete A-bands within the muscle cells is disrupted. In C. elegans, myosin filaments no longer appear as continuous longitudinally oriented fibers across the muscle quadrants.
WB:WBPaper00001894
WB:WBPerson2021
body wall muscle thick myofilament organization abnormal
WB:WBPerson2021
The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants.
body wall muscle actin organization abnormal
C_elegans_phenotype_ontology
body wall muscle thin myofilament organization abnormal
WBPhenotype:0001570
body wall muscle actin organization defective
The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants.
WB:WBPaper00001894
WB:WBPerson2021
body wall muscle thin myofilament organization abnormal
WB:WBPerson2021
Variations in the accumulation of muscle proteins at membranes where adjacent muscle cells contact each other and the hypodermis compared to control. In C. elegans, during early embryonic body wall muscle development, muscle, basement membrane, and hypodermal components are all colocalized in a continuous linear structure at the site of muscle-hypodermal contact.
body wall muscle cell polarization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001571
body wall muscle cell polarization variant
Variations in the accumulation of muscle proteins at membranes where adjacent muscle cells contact each other and the hypodermis compared to control. In C. elegans, during early embryonic body wall muscle development, muscle, basement membrane, and hypodermal components are all colocalized in a continuous linear structure at the site of muscle-hypodermal contact.
WB:WBPaper00001895
Animals that are not ordinarily male, exhibit male-specific attributes. In C. elegans, XX animals exhibit male-specific attributes.
C_elegans_phenotype_ontology
WBPhenotype:0001572
masculinized
Animals that are not ordinarily male, exhibit male-specific attributes. In C. elegans, XX animals exhibit male-specific attributes.
WB:WBPaper00000178
WB:WBPaper00001206
WB:WBPerson712
Animals exhibit variations in the response to the addition of nicotine compared to that observed in control animals. Nicotine is a cholinergic agonist.
nicotine response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001573
nicotine response variant
Animals exhibit variations in the response to the addition of nicotine compared to that observed in control animals. Nicotine is a cholinergic agonist.
WB:WBPerson557
Animals exhibit variations in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology.
ATP levels abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001574
ATP levels variant
Animals exhibit variations in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit a decrease in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology.
C_elegans_phenotype_ontology
WBPhenotype:0001575
ATP levels reduced
Animals exhibit a decrease in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology.
WB:WBPerson2021
WB:WBPerson557
Variations in the spatial distribution of the mitochondria within the cell compared to control.
mitochondria spacing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001576
mitochondria spacing variant
Variations in the spatial distribution of the mitochondria within the cell compared to control.
GO:0048311
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the parallel arrangement of mitochondria within a cell compared to control.
mitochondria alignment abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001577
mitochondria alignment variant
Animals exhibit variations in the parallel arrangement of mitochondria within a cell compared to control.
WB:WBPaper00028954
Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001578
cholinergic agonist resistant
Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson557
Animals respond to a cholinergic agonist at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001579
cholinergic agonist hypersensitive
Animals respond to a cholinergic agonist at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Any variation in the progression of the controlled breakdown of the nuclear envelope, compared to control.
nuclear envelope breakdown abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001580
Possible XP.
nuclear envelope breakdown variant
Any variation in the progression of the controlled breakdown of the nuclear envelope, compared to control.
GO:0051081
WB:WBPerson2021
WB:WBPerson557
Levels of transcripts associated with genes on the X chromosome are increased compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001581
X linked gene expression enhanced
Levels of transcripts associated with genes on the X chromosome are increased compared to control.
WB:WBPaper00001011
WB:WBPerson712
Levels of transcripts associated with genes on the X chromosome are decreased compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001582
X linked gene expression reduced
Levels of transcripts associated with genes on the X chromosome are decreased compared to control.
WB:WBPaper00001011
WB:WBPerson712
Animals segregate progeny with 3 X chromosomes.
C_elegans_phenotype_ontology
WBPhenotype:0001583
XXX progeny
Animals segregate progeny with 3 X chromosomes.
WB:WBPaper00000179
WB:WBPerson712
Any variation in the movement of chromosomes to the spindle equator during mitosis compared to control animals.
chromosome alignment at metaphase plate abnormal
chromosome alignment at metaphase plate variant
C_elegans_phenotype_ontology
chromosome congression
WBPhenotype:0001584
chromosome alignment variant
Any variation in the movement of chromosomes to the spindle equator during mitosis compared to control animals.
GO:0051310
WB:WBPerson557
Any variation in a cell's ability to divide asymmetrically to produce two daughter cells with different developmental potentials compared to control.
asymmetric cell division abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001585
asymmetric cell division variant
Any variation in a cell's ability to divide asymmetrically to produce two daughter cells with different developmental potentials compared to control.
GO:0008356
WB:WBPerson2021
WB:WBPerson557
Animals contain more than one anchor cell. In C. elegans, presumptive ventral uterine cells undergo fate transformation and instead acquire the properties of an anchor cell (often due to defects in lateral signaling).
double anchor cell
C_elegans_phenotype_ontology
WBPhenotype:0001586
multiple anchor cells
Animals contain more than one anchor cell. In C. elegans, presumptive ventral uterine cells undergo fate transformation and instead acquire the properties of an anchor cell (often due to defects in lateral signaling).
WB:WBPaper00001423
WB:WBPerson2021
Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
actin organization biogenesis variant
actin organization biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001587
Possible XP.
actin organization biogenesis phenotype
Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
GO:0030036
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas).
microtubule organization biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001588
Possible XP.
microtubule organization biogenesis variant
Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas).
GO:0000226
WB:WBPerson2021
WB:WBPerson557
Any variation that alters the characteristic de novo formation of a microtubule compared to control.
microtubule nucleation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001589
microtubule nucleation variant
Any variation that alters the characteristic de novo formation of a microtubule compared to control.
GO:0007020
Any variation that alters the characteristic removal of tubulin heterodimers from one or both ends of a microtubule compared to control.
microtubule depolymerization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001590
microtubule depolymerization variant
Any variation that alters the characteristic removal of tubulin heterodimers from one or both ends of a microtubule compared to control.
GO:0007019
Any variation that alters the characteristic addition of tubulin heterodimers to one or both ends of a microtubule compared to control.
microtubule polymerization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001591
microtubule polymerization variant
Any variation that alters the characteristic addition of tubulin heterodimers to one or both ends of a microtubule compared to control.
GO:0046785
Alternating periods of stopping and moving; Motion is interrupted by periods of inactivity lasting several seconds.
C_elegans_phenotype_ontology
WBPhenotype:0001592
fainter
Alternating periods of stopping and moving; Motion is interrupted by periods of inactivity lasting several seconds.
WB:WBPaper00031286
Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control. In C. elegans this silencing occurs only in the germline.
transgene silencing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001593
transgene silencing variant
Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control. In C. elegans this silencing occurs only in the germline.
WB:WBPaper00005399
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the germline, compared to control.
germline transgene silencing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001594
germline transgene silencing variant
Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the germline, compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the soma, compared to control.
somatic transgene silencing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001595
somatic transgene silencing variant
Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the soma, compared to control.
WB:WBPerson2021
WB:WBPerson557
Swelling of the tail hypodermis resulting in a prematurely-truncated and thickened appearance of the tail. In C. elegans, this is usually applies to hermaphrodites.
C_elegans_phenotype_ontology
WBPhenotype:0001596
tail bobbed
Swelling of the tail hypodermis resulting in a prematurely-truncated and thickened appearance of the tail. In C. elegans, this is usually applies to hermaphrodites.
WB:WBPaper00024194
WB:WBPerson712
Any variation that results in a fewer than control number of muscle cells.
C_elegans_phenotype_ontology
WBPhenotype:0001597
muscle missing
Any variation that results in a fewer than control number of muscle cells.
WB:WBPaper00001423
WB:WBPaper00002946
WB:WBPerson2021
Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for control animals.
inhibitor of serotonin uptake abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001598
inhibitor of serotonin uptake variant
Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for control animals.
WB:WBPerson712
Animals fail to respond to the concentration of ouabain that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, resistance to ouabain is often assayed via body contraction response.
C_elegans_phenotype_ontology
WBPhenotype:0001599
ouabain resistant
Animals fail to respond to the concentration of ouabain that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, resistance to ouabain is often assayed via body contraction response.
WB:WBPaper00000484
WB:WBPerson2021
Animals require increased concentration or longer exposure to ouabain to elicit the rapid muscular contractions seen in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001600
contraction response to ouabain resistant
Animals require increased concentration or longer exposure to ouabain to elicit the rapid muscular contractions seen in control animals.
WB:WBPaper00000484
Animals fail to respond to the concentration of biogenic amine receptor antagonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
serotonin receptor antagonist
C_elegans_phenotype_ontology
WBPhenotype:0001601
biogenic amine receptor antagonist resistant
Animals fail to respond to the concentration of biogenic amine receptor antagonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson712
Animals fail to respond to the concentration of methiothepin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001602
methiothepin resistant
Animals fail to respond to the concentration of methiothepin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00031241
WB:WBPerson721
Animals fail to respond to the concentration of cyproheptadine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001603
cyproheptadine resistant
Animals fail to respond to the concentration of cyproheptadine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00031241
WB:WBPerson721
Animals fail to respond to the concentration of mianserin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
dibenzazepine resistant
WBPhenotype:0001604
mianserin resistant
Animals fail to respond to the concentration of mianserin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00031241
WB:WBPerson721
Animals do not live longer in response to mianserin compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001605
extended life span response to mianserin resistant
Animals do not live longer in response to mianserin compared to control.
WB:WBPaper00031241
WB:WBPerson721
Animals respond to ethanol at a lower concentration or a shorter exposure compared to control animals.
alcohol sensitive
C_elegans_phenotype_ontology
WBPhenotype:0001606
ethanol hypersensitive
Animals respond to ethanol at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00002358
WB:WBPerson712
Animals become paralyzed in response to ethanol at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001607
paralysis response to ethanol hypersensitive
Animals become paralyzed in response to ethanol at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00002358
WB:WBPerson712
Animals respond to the anesthetic enflurane at lower concentrations or shorter exposure times than control animals.
C_elegans_phenotype_ontology
ether hypersensitive
WBPhenotype:0001608
enflurane hypersensitive
Animals respond to the anesthetic enflurane at lower concentrations or shorter exposure times than control animals.
WB:WBPaper00002037
WB:WBPerson721
Animals respond to the anesthetic isoflurane at lower concentrations or shorter response times than control animals.
C_elegans_phenotype_ontology
ether hypersensitive
WBPhenotype:0001609
isoflurane hypersensitive
Animals respond to the anesthetic isoflurane at lower concentrations or shorter response times than control animals.
WB:WBPaper00002037
WB:WBPerson721
Animals respond to the anesthetic ether at lower concentrations or shorter response times than control animals.
C_elegans_phenotype_ontology
ether hypersensitive
WBPhenotype:0001610
diethyl ether hypersensitive
Animals respond to the anesthetic ether at lower concentrations or shorter response times than control animals.
WB:WBPaper00001063
WB:WBPaper00002037
WB:WBPerson721
Animals respond to the lipid-soluble anesthetic halothane at lower concentrations or shorter response times compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001611
halothane hypersensitive
Animals respond to the lipid-soluble anesthetic halothane at lower concentrations or shorter response times compared to control animals.
WB:WBPaper00000958
WB:WBPaper00031286
WB:WBPerson721
Animals fail to respond to the concentration of ethanol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to ethanol to elicit the response compared to control animals. In C.elegans the phenotype designation Jud is short for JUDang, which is Korean for resistant to alcohol.
Jud
alcohol resistant
C_elegans_phenotype_ontology
WBPhenotype:0001612
ethanol resistant
Animals fail to respond to the concentration of ethanol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to ethanol to elicit the response compared to control animals. In C.elegans the phenotype designation Jud is short for JUDang, which is Korean for resistant to alcohol.
WB:WBPaper00002358
WB:WBPaper00031371
WB:WBPerson557
WB:WBPerson712
Animals in the presence of ethanol continue to respond to touch under conditions when control worms have stopped responding to stimuli.
C_elegans_phenotype_ontology
WBPhenotype:0001613
paralysis response to ethanol resistant
Animals in the presence of ethanol continue to respond to touch under conditions when control worms have stopped responding to stimuli.
WB:WBPaper00031371
WB:WBPerson712
Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals.
anticonvulsant response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001614
anticonvulsant response variant
Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals.
WB:WBPerson557
Animals fail to respond to the concentration of compounds that act as anticonvulsants that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001615
anticonvulsant resistant
Animals fail to respond to the concentration of compounds that act as anticonvulsants that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00024698
WB:WBPerson557
WB:WBPerson712
Animals fail to respond to the concentration of trimethadione, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001616
trimethadione resistant
Animals fail to respond to the concentration of trimethadione, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00024698
WB:WBPerson557
WB:WBPerson712
Animals fail to respond to the concentration of ethosuximide, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001617
ethosuximide resistant
Animals fail to respond to the concentration of ethosuximide, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson712
Animals fail to respond to the concentration of the anesthetic halothane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001618
halothane resistant
Animals fail to respond to the concentration of the anesthetic halothane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00004721
WB:WBPerson557
WB:WBPerson712
Animals fail to respond to the concentration of the volatile anesthetic isoflurane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001619
isoflurane resistant
Animals fail to respond to the concentration of the volatile anesthetic isoflurane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00004721
WB:WBPerson712
Animals exhibit variations in their response to oxidative stress compared to that observed in control animals.
organism oxidative stress response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001620
organism oxidative stress response variant
Animals exhibit variations in their response to oxidative stress compared to that observed in control animals.
WB:WBPerson557
Animals respond to a lower concentration of reactive oxygen species or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001621
organism oxidative stress response hypersensitive
Animals respond to a lower concentration of reactive oxygen species or a shorter exposure compared to control animals.
WB:WBPerson2021
Animals lay eggs at a greater rate in response to exogenous serotonin compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001622
egg laying serotonin hypersensitive
Animals lay eggs at a greater rate in response to exogenous serotonin compared to control animals.
WB:WBPaper00002487
WB:WBPerson712
Any variation in the posture of the male tail after application of exogenous serotonin compared to control. In C. elegans, males respond with a tight ventral curling of the male tail in response to serotonin.
male tail curling serotonin abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001623
male tail curling serotonin variant
Any variation in the posture of the male tail after application of exogenous serotonin compared to control. In C. elegans, males respond with a tight ventral curling of the male tail in response to serotonin.
WB:WBPaper00001861
WB:WBPerson557
Animals fail to respond to the concentration of serotonin that elicits a male tail curling response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body.
C_elegans_phenotype_ontology
WBPhenotype:0001624
male tail curling serotonin resistant
Animals fail to respond to the concentration of serotonin that elicits a male tail curling response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body.
WB:WBPaper00001861
WB:WBPerson557
Males respond to serotonin by curling their tails at a lower concentration or a shorter exposure compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body.
C_elegans_phenotype_ontology
WBPhenotype:0001625
male tail curling serotonin hypersensitive
Males respond to serotonin by curling their tails at a lower concentration or a shorter exposure compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body.
WB:WBPaper00001861
WB:WBPaper00028762
WB:WBPerson557
Any variation in the locomotion rate after application of exogenous serotonin compared to control.
locomotion rate serotonin abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001626
locomotion rate serotonin variant
Any variation in the locomotion rate after application of exogenous serotonin compared to control.
WB:WBPaper00002141
The decrease in locomotion rate in the presence of serotonin is greater than control animals.
C_elegans_phenotype_ontology
locomotion rate serotonin reduced
WBPhenotype:0001627
locomotion rate serotonin hypersensitive
The decrease in locomotion rate in the presence of serotonin is greater than control animals.
WB:WBPaper00002141
Animals fail to decrease their locomotion rate in response the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
locomotion rate serotonin increased
WBPhenotype:0001628
locomotion rate serotonin resistant
Animals fail to decrease their locomotion rate in response the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00002141
Any variation in egg laying behavior after application of exogenous serotonin compared to control. In C. elegans, serotonin induces egg laying.
egg laying serotonin abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001629
egg laying serotonin variant
Any variation in egg laying behavior after application of exogenous serotonin compared to control. In C. elegans, serotonin induces egg laying.
WB:WBPaper00000635
WB:WBPerson712
Any variation in the developmental progression of the intestine that leads to a blockage in the alimentary canal.
Gob
C_elegans_phenotype_ontology
WBPhenotype:0001630
gut obstructed
Any variation in the developmental progression of the intestine that leads to a blockage in the alimentary canal.
WB:WBPerson2021
WB:WBPerson557
Animals produce ova/sperm that contain no X chromosome in a nonmendelian segregation pattern.
nullo X gamete abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001631
nullo X gamete
Animals produce ova/sperm that contain no X chromosome in a nonmendelian segregation pattern.
WB:WBPaper00000179
WB:WBPerson712
Animals produce ova/sperm that contain 2 X chromosomes.
C_elegans_phenotype_ontology
WBPhenotype:0001632
diplo X gamete
Animals produce ova/sperm that contain 2 X chromosomes.
WB:WBPaper00000179
WB:WBPerson712
Animals produce ova/sperm that contain lethal factors as a result of chromosomal disjunction defects.
C_elegans_phenotype_ontology
WBPhenotype:0001633
lethal gamete
Animals produce ova/sperm that contain lethal factors as a result of chromosomal disjunction defects.
WB:WBPaper00000179
WB:WBPerson712
Animals respond to compounds that elicit electrophilic stress at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001634
organism electrophilic stress hypersensitive
Animals respond to compounds that elicit electrophilic stress at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals contain an excess number of pharyngeal cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate.
C_elegans_phenotype_ontology
WBPhenotype:0001635
excess pharyngeal cells
Animals contain an excess number of pharyngeal cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate.
WB:WBPaper00001584
WB:WBPaper00002922
WB:WBperson2021
Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage.
C_elegans_phenotype_ontology
WBPhenotype:0001636
excess intestinal cells
Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage.
WB:WBPaper00001584
WB:WBPaper00002330
WB:WBperson2021
Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells.
C_elegans_phenotype_ontology
WBPhenotype:0001637
no Intestine
Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells.
WB:WBPaper00002946
WB:WBperson2021
OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes.
C_elegans_phenotype_ontology
WBPhenotype:0001638
obsolete endosome fusion defective
true
OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes.
GO:0034058
WB:WBPaper00029049
WB:WBPerson712
Animals exhibit a decrease in their high-speed movement in the forward direction with brief backward movement compared to control. In C. elegans, Animals do not move more than a few body lengths from their starting position and searches occur locally with pivoting behavior.
C_elegans_phenotype_ontology
lurcher
path range decreased
WBPhenotype:0001639
roaming reduced
Animals exhibit a decrease in their high-speed movement in the forward direction with brief backward movement compared to control. In C. elegans, Animals do not move more than a few body lengths from their starting position and searches occur locally with pivoting behavior.
WB:WBPaper00003743
WB:WBPaper00031455
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson712
Animals are unable to acidify compartments to the same level as that observed in control animals given the same stimulus.
acidification level abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001640
acidification level defective
Animals are unable to acidify compartments to the same level as that observed in control animals given the same stimulus.
WB:WBPaper00031246
WB:WBPerson712
Animals lack or exhibit defects in the posterior body muscle contractions during the defecation cycle.
C_elegans_phenotype_ontology
pBoc
WBPhenotype:0001641
posterior body wall contraction defective
Animals lack or exhibit defects in the posterior body muscle contractions during the defecation cycle.
WB:WBPaper00031426
WB:WBPerson712
Variations that disrupt stereotypical embryonic cleavage patterns (such as cleavage rate, division axes or asymmetric division).
C_elegans_phenotype_ontology
WBPhenotype:0001642
cell cleavage variant emb
Variations that disrupt stereotypical embryonic cleavage patterns (such as cleavage rate, division axes or asymmetric division).
GO:0040016
WB:WBPaper00001032
WB:WBPerson2021
Embryos generate an excess number of hypodermal cells compared to control.
Skn
C_elegans_phenotype_ontology
WBPhenotype:0001643
excess hypodermal cells
Embryos generate an excess number of hypodermal cells compared to control.
WB:WBPerson2021
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of proteins in the organism compared to control.
protein metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001644
protein metabolism variant
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of proteins in the organism compared to control.
WB:WBPerson557
Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control.
protein degradation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001645
protein degradation variant
Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control.
GO:0030163
WB:WBPerson2021
Embryos fail to generate cells that exhibit pharyngeal specification.
Pha
C_elegans_phenotype_ontology
WBPhenotype:0001646
no pharynx
Embryos fail to generate cells that exhibit pharyngeal specification.
WB:WBPaper00001521
WB:WBPerson2021
Any variation in the progression of the posterior portion of the pharynx over time compared to control. In C. elegans the posterior region includes the isthmus and terminal bulb (second bulb).
posterior pharynx abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001647
posterior pharynx variant
Any variation in the progression of the posterior portion of the pharynx over time compared to control. In C. elegans the posterior region includes the isthmus and terminal bulb (second bulb).
WB:WBPerson2021
WB:WBPerson557
Embryos fail to generate cells that give rise to the posterior portion of the pharynx. In C. elegans, the MS blastomere- derived pharyngeal cells constitute the posterior portion of the pharynx.
C_elegans_phenotype_ontology
WBPhenotype:0001648
no posterior pharynx
Embryos fail to generate cells that give rise to the posterior portion of the pharynx. In C. elegans, the MS blastomere- derived pharyngeal cells constitute the posterior portion of the pharynx.
WB:WBPaper00002330
WB:WBPerson2021
Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals.
5 FU resistant
C_elegans_phenotype_ontology
WBPhenotype:0001649
Fluorouracil resistant
Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals.
WB:WBPaper00031571
WB:WBPerson721
Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei.
C_elegans_phenotype_ontology
WBPhenotype:0001650
germ cell death response to 5 FU resistant
Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei.
WB:WBPaper00031571
WB:WBPerson721
Animals grow well during or after exposure to 5-FU under conditions where control animals are growth inhibited.
C_elegans_phenotype_ontology
WBPhenotype:0001651
growth arrest response to 5 FU resistant
Animals grow well during or after exposure to 5-FU under conditions where control animals are growth inhibited.
WB:WBPaper00031571
WB:WBPerson721
Any variation in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. In C. elegans, this includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap.
anchor cell invasion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001652
anchor cell invasion variant
Any variation in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. In C. elegans, this includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap.
WB:WBPaper00005989
Animals exhibit variations in their response to cadmium compared to that observed in control animals.
cadmium response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001653
cadmium response variant
Animals exhibit variations in their response to cadmium compared to that observed in control animals.
WB:WBPerson557
Animals fail to respond to the concentration of cadmium that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to cadmium to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001654
cadmium resistant
Animals fail to respond to the concentration of cadmium that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to cadmium to elicit the response compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals respond to cadmium at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001655
cadmium hypersensitive
Animals respond to cadmium at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Any variation in the progression of the leader cell that guides and shapes the outgrowth of the gonad while crawling along the body wall to force the germline to extend into a long tubular shape over time from its formation to its mature structure compared to control.
distal tip cell development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001656
distal tip cell development variant
Any variation in the progression of the leader cell that guides and shapes the outgrowth of the gonad while crawling along the body wall to force the germline to extend into a long tubular shape over time from its formation to its mature structure compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the specialized region of connection between two cells or between a cell and the extracellular matrix compared to control.
cell junction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001657
cell junction variant
Animals exhibit variations in the specialized region of connection between two cells or between a cell and the extracellular matrix compared to control.
GO:0030054
WB:WBPaper00031590
WB:WBPerson712
Animals exhibit variations in the specialized region of connection between two cells compared to control.
intercellular junction abnormal
C_elegans_phenotype_ontology
cell cell junction abnormal
WBPhenotype:0001658
intercellular junction variant
Animals exhibit variations in the specialized region of connection between two cells compared to control.
GO:0005911
WB:WBPaper00031590
WB:WBPerson712
Any variation in the form, structure or composition of the somatic gonad structure that connects the distal gonad arm to the uterus compared to control (Wormatlas).
spermatheca morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001659
spermatheca morphology variant
Any variation in the form, structure or composition of the somatic gonad structure that connects the distal gonad arm to the uterus compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
The two morphologically bilaterally symmetric gustatory neurons ASE left (ASEL) and ASE right (ASER) fail to undergo a left/right asymmetric diversification in cell fate.
2ASEL
2ASER
C_elegans_phenotype_ontology
WBPhenotype:0001660
loss of asymmetry ASE
The two morphologically bilaterally symmetric gustatory neurons ASE left (ASEL) and ASE right (ASER) fail to undergo a left/right asymmetric diversification in cell fate.
WB:WBPaper00030973
WB:WBPerson2021
The two morphologically bilaterally symmetric olfactory neurons AWC left (AWCL) and AWC right (AWCR) fail to undergo a left/right asymmetric diversification in cell fate.
2 AWC off
2 AWC on
C_elegans_phenotype_ontology
WBPhenotype:0001661
loss of asymmetry AWC
The two morphologically bilaterally symmetric olfactory neurons AWC left (AWCL) and AWC right (AWCR) fail to undergo a left/right asymmetric diversification in cell fate.
WB:WBPaper00003760
WB:WBPerson2021
Any variation in the progression of the somatic gonad structure that connects the distal gonad arm to the uterus over time from an initial condition to a later condition compared to control animals.
spermatheca development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001662
spermatheca development variant
Any variation in the progression of the somatic gonad structure that connects the distal gonad arm to the uterus over time from an initial condition to a later condition compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Animals fail to respond to the levels of reactive oxygen species that elicit a response in control animals.
Oxr
C_elegans_phenotype_ontology
WBPhenotype:0001663
organism oxidative stress resistant
Animals fail to respond to the levels of reactive oxygen species that elicit a response in control animals.
WB:WBPerson2021
The frequency of sex chromosome segregation is perturbed, resulting in the production of exceptional gametes (e.g. ova or sperm) and populations with a sex ratio altered from the rate of 1:500 as observed for control populations.
C_elegans_phenotype_ontology
WBPhenotype:0001664
X chromosome nondisjunction
The frequency of sex chromosome segregation is perturbed, resulting in the production of exceptional gametes (e.g. ova or sperm) and populations with a sex ratio altered from the rate of 1:500 as observed for control populations.
WB:WBPaper00000179
WB:WBPaper00000565
WB:WBPerson712
Lower numbers of male progeny occur in the population compared to control populations. In C. elegans, the low incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an decrease in X chromosome nondisjunction.
C_elegans_phenotype_ontology
WBPhenotype:0001665
low incidence male progeny
Lower numbers of male progeny occur in the population compared to control populations. In C. elegans, the low incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an decrease in X chromosome nondisjunction.
WB:WBPaper00000565
WB:WBPerson712
Animals respond to iononizing radiation at a lower dose or a shorter exposure compared to control animals. Iononizing radiation has a wavelength in the 10 to 0.01 nanometer range. In C. elegans, increased sensitivity to X-ray irradiation is often observed as a decrease in survival upon exposure compared to control animals given the same treatment.
C_elegans_phenotype_ontology
WBPhenotype:0001666
organism hypersensitive X ray irradiation
Animals respond to iononizing radiation at a lower dose or a shorter exposure compared to control animals. Iononizing radiation has a wavelength in the 10 to 0.01 nanometer range. In C. elegans, increased sensitivity to X-ray irradiation is often observed as a decrease in survival upon exposure compared to control animals given the same treatment.
WB:WBPaper00000565
WB:WBPaper00003886
WB:WBPerson712
Animals respond to the chemical mutagen methyl methanesulfonate (MMS) a methanesulfonate ester and alkylating agent at a lower concentration or a shorter exposure compared to control animals. In C. elegans, increased sensitivity to MMS can be observed as a decrease in egg hatch upon acute exposure or inhibition of growth after chronic exposure compared to control animals given the same treatment.
MMS hypersensitive
C_elegans_phenotype_ontology
WBPhenotype:0001667
methyl methanesulfonate hypersensitive
Animals respond to the chemical mutagen methyl methanesulfonate (MMS) a methanesulfonate ester and alkylating agent at a lower concentration or a shorter exposure compared to control animals. In C. elegans, increased sensitivity to MMS can be observed as a decrease in egg hatch upon acute exposure or inhibition of growth after chronic exposure compared to control animals given the same treatment.
WB:WBPaper00000565
WB:WBPerson712
An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control.
C_elegans_phenotype_ontology
oocyte number increased
WBPhenotype:0001668
oocyte accumulation
An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control.
WB:WBPaper00006281
WB:WBPaper00030855
Animals exhibit a variation in the ratio of synaptic vesicles per synapse of a neuron, compared to control animals.
presynaptic vesicle number abnormal
C_elegans_phenotype_ontology
synaptic vesicle number abnormal
WBPhenotype:0001669
presynaptic vesicle number variant
Animals exhibit a variation in the ratio of synaptic vesicles per synapse of a neuron, compared to control animals.
WB:WBPaper00027305
WB:WBPerson712
Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to control animals.
WBPhenotype:0001322
C_elegans_phenotype_ontology
synaptic vesicle number reduced
WBPhenotype:0001670
presynaptic vesicle number reduced
Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to control animals.
WB:WBPaper00027305
WB:WBPerson712
Animals display variations in the distribution of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals.
vesicle organization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001671
vesicle organization variant
Animals display variations in the distribution of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the extension of the part of the axon that forms a bridge between body regions, compared to control animals.
commisure growth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001672
commisure growth variant
Animals exhibit variations in the extension of the part of the axon that forms a bridge between body regions, compared to control animals.
WB:WBPerson2021
WB:WBPerson712
Animals exhibit variations in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation, compared to control.
telomere homeostasis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001673
telomere homeostasis variant
Animals exhibit variations in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation, compared to control.
GO:0032204
WB:WBPaper00031585
WB:WBPerson712
Animals exhibit variations in the sequence or organization of the components of the terminal region of its chromosome, (i.e. telomere, which serves to stabilize the chromosome) compared to control.
telomere morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001674
telomere morphology variant
Animals exhibit variations in the sequence or organization of the components of the terminal region of its chromosome, (i.e. telomere, which serves to stabilize the chromosome) compared to control.
GO:0000781
WB:WBPaper00003886
WB:WBPerson712
Males exhibit variations in the reproductive system, from its formation to the mature structure compared to control.
male gonad development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001675
male gonad development variant
Males exhibit variations in the reproductive system, from its formation to the mature structure compared to control.
WB:WBPerson712
Animals exhibit variations in the structure or composition of any neuron within the class of sensory neurons responsible for relaying mechanical stimuli to the animal compared to control.
touch receptor cell morphology abnormal
C_elegans_phenotype_ontology
mechanosensory neuron abnormal
microtubule cell morphology abnormal
WBPhenotype:0001676
touch receptor cell morphology variant
Animals exhibit variations in the structure or composition of any neuron within the class of sensory neurons responsible for relaying mechanical stimuli to the animal compared to control.
WB:WBPaper00000550
WB:WBPerson712
Animals display cuticle components displayed by animals of a different developmental stage, compared to control.
Srf
stage specific cuticle antigenicity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001677
stage specific cuticle antigenicity variant
Animals display cuticle components displayed by animals of a different developmental stage, compared to control.
WB:WBPaper00002589
WB:WBPerson712
Animals produce cuticles that vary in components such as proteins or carbohydrates, observed in control animals of the same developmental stage and raised under the same conditions.
cuticle physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001678
cuticle physiology variant
Animals produce cuticles that vary in components such as proteins or carbohydrates, observed in control animals of the same developmental stage and raised under the same conditions.
WB:WBPaper00001576
WB:WBPerson712
Neurons have more than one process extending from the cell body.
C_elegans_phenotype_ontology
WBPhenotype:0001679
multipolar neuron
Neurons have more than one process extending from the cell body.
WB:WBPaper00031901
WB:WBPerson712
Vulval precursor cells forgo further cell division and fuse to the hypodermis instead of adopting their intended fate (becoming primary, secondary or tertiary vulval cells).
C_elegans_phenotype_ontology
F fate abnormal
VPC fused fate abnormal
WBPhenotype:0001680
adoption of fused vulval cell fate
Vulval precursor cells forgo further cell division and fuse to the hypodermis instead of adopting their intended fate (becoming primary, secondary or tertiary vulval cells).
WB:WBPerson2021
WB:WBPerson712
The alignment of the spindle relative to other cellular structures varies from that observed in control animals.
spindle orientation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001681
spindle orientation variant
The alignment of the spindle relative to other cellular structures varies from that observed in control animals.
GO:0051294
WB:WBPaper00031898
WB:WBPerson712
Organisms respond to UV at a higer dose or a longer exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001682
organism UV resistant
Organisms respond to UV at a higer dose or a longer exposure compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Variations that specifically disrupt sperm production in XX hermaphrodites. By contrast, spermatogenesis in XO males remains unaffected.
C_elegans_phenotype_ontology
WBPhenotype:0001683
spermatogenesis defective hermaphrodite
Variations that specifically disrupt sperm production in XX hermaphrodites. By contrast, spermatogenesis in XO males remains unaffected.
WB:WBPaper00002113
WB:WBPaper00002631
The rates of synaptic vesicle exocytosis and endocytosis vary from that observed in control animals.
synaptic vesicle homeostasis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001684
synaptic vesicle homeostasis variant
The rates of synaptic vesicle exocytosis and endocytosis vary from that observed in control animals.
WB:WBPaper00031872
WB:WBPerson712
The region opposite to the presynaptic region deviates in the structure, configuration or ratio of its components specific for receiving signals from the other side of the synapse compared to control.
postsynaptic region morphology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001685
postsynaptic region morphology variant
The region opposite to the presynaptic region deviates in the structure, configuration or ratio of its components specific for receiving signals from the other side of the synapse compared to control.
WB:WBPaper00031872
WB:WBPerson712
Animals exhibit variations in any physical or chemical process in the region, opposite to the presynaptic region, which is required for receiving signals from the other side of the synapse compared to control.
postsynaptic region physiology abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001686
postsynaptic region physiology variant
Animals exhibit variations in any physical or chemical process in the region, opposite to the presynaptic region, which is required for receiving signals from the other side of the synapse compared to control.
WB:WBPerson2021
WB:WBPerson557
Cuticles of animals or cuticular extracts exhibit an altered pattern of antibody binding compared to Bristol N2 animals of the same developmental stage.
Srf
surface antigenicity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001687
surface antigenicity variant
Cuticles of animals or cuticular extracts exhibit an altered pattern of antibody binding compared to Bristol N2 animals of the same developmental stage.
WB:WBPaper00001280
WB:WBPerson712
The electron dense, amorphous envelope that comprises the outermost layer of the cuticle varies in composition from that observed in control animals of the same developmental stage. The integrity of the surface coat is often revealed by an altered antigenicity or biochemical make up.
Srf
surface coat abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001688
surface coat variant
The electron dense, amorphous envelope that comprises the outermost layer of the cuticle varies in composition from that observed in control animals of the same developmental stage. The integrity of the surface coat is often revealed by an altered antigenicity or biochemical make up.
GO:0060104
Cuticles or cuticular extracts do not bind antibodies that are observed to bind the surfaces or cuticular extracts of Bristol N2 animals of the same developmental stage.
Srf
C_elegans_phenotype_ontology
WBPhenotype:0001689
surface antigen negative
Cuticles or cuticular extracts do not bind antibodies that are observed to bind the surfaces or cuticular extracts of Bristol N2 animals of the same developmental stage.
WB:WBPaper00001280
WB:WBPerson712
Animals display surface antigens throughout all larval stages, unlike Bristol N2 worms, which display the antigens only during one larval stage.
Cld
C_elegans_phenotype_ontology
WBPhenotype:0001690
constitutive larval display
Animals display surface antigens throughout all larval stages, unlike Bristol N2 worms, which display the antigens only during one larval stage.
WB:WBPaper00002589
WB:WBPerson712
Germ nuclei are misplaced in the gonad and are observed in the rachis. Sheath cells are observed protruding between these nuclei. Meiotic or mitotic specification of germ nuclei is not affected.
germ line morphogenesis(Glm)
C_elegans_phenotype_ontology
WBPhenotype:0001691
germ nuclei rachis
Germ nuclei are misplaced in the gonad and are observed in the rachis. Sheath cells are observed protruding between these nuclei. Meiotic or mitotic specification of germ nuclei is not affected.
WB:WBPaper00031889
WB:WBPerson712
Animals are not induced to display surface antigens by exposure to pheromone as observed for Bristol N2 animals.
ILD abnormal
pheromone induced larval display abnormal
C_elegans_phenotype_ontology
induced larval display abnormal
WBPhenotype:0001692
pheromone induced larval display defective
Animals are not induced to display surface antigens by exposure to pheromone as observed for Bristol N2 animals.
WB:WBPaper00002589
WB:WBPerson712
Males have alae that extend into the tail region. Alae are small linear ridges running along the lateral lines of the cuticle. In C. elegans alae do not extend into the tail region (Wormatlas).
Pal
C_elegans_phenotype_ontology
WBPhenotype:0001693
male posterior alae
Males have alae that extend into the tail region. Alae are small linear ridges running along the lateral lines of the cuticle. In C. elegans alae do not extend into the tail region (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Hermaphrodites continue to produce sperm past the time at which the transition to oogenesis normally occurs. Thus, germ cells that would normally become oocytes are transformed into sperm instead.
spermatogenesis to oogenesis switch abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001694
spermatogenesis to oogenesis switch defective
Hermaphrodites continue to produce sperm past the time at which the transition to oogenesis normally occurs. Thus, germ cells that would normally become oocytes are transformed into sperm instead.
WB:WBPaper00001883
WB:WBPaper00002113
WB:WBPerson2021
Animals exhibit variations in their catalytic ability the transfer glycolsyl groups from one compound (donor) to another (acceptor) often measured by a reduction in the amount of glycosylated products compared to that observed in control animals of the same developmental stage.
glycosyltransferase activity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001695
glycosyltransferase activity variant
Animals exhibit variations in their catalytic ability the transfer glycolsyl groups from one compound (donor) to another (acceptor) often measured by a reduction in the amount of glycosylated products compared to that observed in control animals of the same developmental stage.
GO:0016757
WB:WBPerson712
Animals exhibit variations in the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones compared to control.
biosynthesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001696
biosynthesis variant
Animals exhibit variations in the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones compared to control.
GO:0009058
WB:WBPaper00029024
WB:WBPerson712
Animals exhibit variations in the chemical reactions and pathways resulting in the formation of chondroitin sulfate compared to control.
chondroitin biosynthesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001697
chondroitin biosynthesis variant
Animals exhibit variations in the chemical reactions and pathways resulting in the formation of chondroitin sulfate compared to control.
WB:WBPaper00029024
WB:WBPaper00031153
WB:WBPerson712
Animals exhibit variations in the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan compared to control.
heparan sulfate biosynthesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001698
heparan sulfate biosynthesis variant
Animals exhibit variations in the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan compared to control.
WB:WBPaper00029024
WB:WBPaper00031153
WB:WBPerson712
Specific body regions of an animal display variations in movement compared to that observed in control animals.
localized movement abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001699
localized movement variant
Specific body regions of an animal display variations in movement compared to that observed in control animals.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in movement in liquid from that observed for control animals.
swimming abnormal
C_elegans_phenotype_ontology
movement in liquid abnormal
thrashing abnormal
WBPhenotype:0001700
swimming variant
Animals exhibit variations in movement in liquid from that observed for control animals.
WB:WBPaper00031835
WB:WBPerson712
Animals exhibit uncharacteristic muscle contractions during the process by which they travel from one location to another.
C_elegans_phenotype_ontology
convulsive
WBPhenotype:0001701
spastic locomotion
Animals exhibit uncharacteristic muscle contractions during the process by which they travel from one location to another.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the directional changes that separate consecutive runs, from that observed for control animals. In C. elegans, these aberrations include variations in the form or extent of omega turns or reversals (shifts from forward to backward movements).
directionality abnormal
C_elegans_phenotype_ontology
reversal abnormal
turning abnormal
WBPhenotype:0001702
directionality variant
Animals exhibit variations in the directional changes that separate consecutive runs, from that observed for control animals. In C. elegans, these aberrations include variations in the form or extent of omega turns or reversals (shifts from forward to backward movements).
WB:WBPaper00000075
WB:WBPaper00003740
WB:WBPaper00031656
WB:WBPerson712
Any variation in the maximum ventral and dorsal flex of the animal compared to control animals.
body bend abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001703
body bend variant
Any variation in the maximum ventral and dorsal flex of the animal compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Alae contain more cuticular ridges than control animals. In C. elegans alae are composed of three cuticular ridges.
C_elegans_phenotype_ontology
WBPhenotype:0001704
multiple alae
Alae contain more cuticular ridges than control animals. In C. elegans alae are composed of three cuticular ridges.
WB:WBPaper00026841
WB:WBPerson557
The directed movement of molecules between the nucleus and the cytoplasm is impaired.
nucleocytoplasmic transport abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001705
nucleocytoplasmic transport defective
The directed movement of molecules between the nucleus and the cytoplasm is impaired.
GO:0006913
WB:WBPerson557
The directed movement of substances out of the nucleus is impaired.
nuclear export abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001706
nuclear export defective
The directed movement of substances out of the nucleus is impaired.
GO:0051168
WB:WBPerson557
The directed movement of substances into the nucleus is impaired.
nuclear import abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001707
nuclear import defective
The directed movement of substances into the nucleus is impaired.
GO:0051170
WB:WBPerson557
The directed movement of a protein from the nucleus into the cytoplasm is impaired.
protein export from nucleus abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001708
protein export from nucleus defective
The directed movement of a protein from the nucleus into the cytoplasm is impaired.
GO:0006611
WB:WBPerson557
Animals exhibit variations in light/dark cycle recurrence of reactions to stress conditions compared to that observed for control animals.
rhythmic tolerance to stress abnormal
C_elegans_phenotype_ontology
circadian variation in stress tolerance abnormal
WBPhenotype:0001709
rhythmic tolerance to stress variant
Animals exhibit variations in light/dark cycle recurrence of reactions to stress conditions compared to that observed for control animals.
WB:WBPaper00032037
WB:WBPerson712
Animals exhibit variations in light/dark cycle recurrence of reactions to osmotic stress compared to that observed for control animals.
rhythmic tolerance to osmotic stress abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001710
rhythmic tolerance to osmotic stress variant
Animals exhibit variations in light/dark cycle recurrence of reactions to osmotic stress compared to that observed for control animals.
WB:WBPaper00032037
WB:WBPerson712
Animals exhibit variations in actions or responses that occur with measurable periodicity, from that observed for control animals.
rhythmic behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001711
rhythmic behavior variant
Animals exhibit variations in actions or responses that occur with measurable periodicity, from that observed for control animals.
GO:0007622
WB:WBPerson712
Animals exhibit variations in the actions or reactions that recur with a periodicity associated with light/dark cycles, compared to control.
circadian rhythm behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001712
circadian rhythm behavior variant
Animals exhibit variations in the actions or reactions that recur with a periodicity associated with light/dark cycles, compared to control.
GO:0048512
WB:WBPaper00032037
WB:WBPerson712
Animals exhibit variations in locomotor activity during its light/dark cycle from that observed in control animals.
locomotory rhythm abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001713
locomotory rhythm variant
Animals exhibit variations in locomotor activity during its light/dark cycle from that observed in control animals.
GO:0045475
WB:WBPaper00031656
WB:WBPerson712
Animals exhibit variations in turning bouts, consisting of one or more sharp turning events separating consecutive runs, which serve to orient the animal within a gradient, compared to control.
pirouette abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001714
pirouette variant
Animals exhibit variations in turning bouts, consisting of one or more sharp turning events separating consecutive runs, which serve to orient the animal within a gradient, compared to control.
WB:WBPaper00003740
WB:WBPaper00026967
WB:WBPerson712
Animals exhibit variations in the number of directional changes over time from that observed for control animals.
frequency of directionality abnormal
pirouette frequency abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001715
pirouette frequency variant
Animals exhibit variations in the number of directional changes over time from that observed for control animals.
WB:WBPaper00031656
WB:WBPerson712
Animals exhibit variations in the velocity of forward translocation of any point along the animal's track from that observed for control animals.
forward point velocity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001716
forward point velocity variant
Animals exhibit variations in the velocity of forward translocation of any point along the animal's track from that observed for control animals.
WB:WBPaper00024949
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson712
Animals exhibit variations in the translocation of the mean position of the rear two-thirds (centroid position) of the animal over time, from that observed for control animals.
centroid velocity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001717
centroid velocity variant
Animals exhibit variations in the translocation of the mean position of the rear two-thirds (centroid position) of the animal over time, from that observed for control animals.
WB:WBPaper00024949
WB:WBPaper00031656
WB:WBPerson712
Animals exhibit variations in the mean translocation of the points along the animal's track compared to control.
instantaneous velocity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001718
instantaneous velocity variant
Animals exhibit variations in the mean translocation of the points along the animal's track compared to control.
WB:WBPaper00024949
WB:WBPerson712
Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
unfolded protein response abnormal
C_elegans_phenotype_ontology
ER unfolded protein response abnormal
UPR
unfolded protein response
WBPhenotype:0001719
unfolded protein response variant
Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
GO:0030968
WB:WBPaper00030877
WB:WBPaper00032003
WB:WBPerson557
WB:WBPerson712
Spermatozoa do not crawl back into the spermatheca after being swept into the uterus by passing oocytes.
spermatozoa retro location abnormal
C_elegans_phenotype_ontology
spermatheca homing abnormal
WBPhenotype:0001720
spermatozoa retro location defective
Spermatozoa do not crawl back into the spermatheca after being swept into the uterus by passing oocytes.
WB:WBPaper00032030
WB:WBPerson712
Animals exhibit variations in the extent of pathogen invasion into the pharynx compared to control. This is often measured as the percentage of animals exhibiting a pathogen-invaded pharynx within a given population.
pathogen infected pharynx abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001721
pathogen infected pharynx variant
Animals exhibit variations in the extent of pathogen invasion into the pharynx compared to control. This is often measured as the percentage of animals exhibiting a pathogen-invaded pharynx within a given population.
WB:WBPaper00032003
WB:WBPerson712
Animals exhibit a greater extent of pathogen invasion into the pharynx compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001722
pathogen infected pharynx increase
Animals exhibit a greater extent of pathogen invasion into the pharynx compared to control.
WB:WBPaper00032003
WB:WBPerson712
Animals exhibit a lesser extent of pathogen invasion into the pharynx compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001723
pathogen infected pharynx decrease
Animals exhibit a lesser extent of pathogen invasion into the pharynx compared to control.
WB:WBPaper00032003
WB:WBPerson712
Animals respond to tunicamycin at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001724
tunicamycin hypersensitive
Animals respond to tunicamycin at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00030877
WB:WBPerson557
Cells exhibit variations in the response to osmotic stress compared to control. In C. elegans, exposure to stress-inducing osmotic conditions invokes cellular changes, including transcriptional up or down-regulation of genes.
osmotic stress response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001725
cellular osmotic stress response variant
Cells exhibit variations in the response to osmotic stress compared to control. In C. elegans, exposure to stress-inducing osmotic conditions invokes cellular changes, including transcriptional up or down-regulation of genes.
WB:WBPaper00032031
WB:WBPerson712
Animals vary in the distance between anterior and posterior ends of the animal from that observed in control animals.
body length abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001726
body length variant
Animals vary in the distance between anterior and posterior ends of the animal from that observed in control animals.
WB:WBPerson712
Animals vary in the distance between dorsal and ventral sides when measured across the body at right angles to the length, from that observed in control animals.
body width abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001727
body width variant
Animals vary in the distance between dorsal and ventral sides when measured across the body at right angles to the length, from that observed in control animals.
WB:WBPerson712
Males differ from control animals in their ability to form copulatory plugs or their placement of these plugs. In C. elegans, males of the Hawaiian strain (CB4856) typically form mating plugs.
mating plug production abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001728
mating plug production variant
Males differ from control animals in their ability to form copulatory plugs or their placement of these plugs. In C. elegans, males of the Hawaiian strain (CB4856) typically form mating plugs.
WB:WBPaper00032027
WB:WBPerson712
Males form copulatory mating plugs.
C_elegans_phenotype_ontology
mating plug plus
plug plus
WBPhenotype:0001729
mating plug produced
Males form copulatory mating plugs.
WB:WBPaper00002770
WB:WBPerson712
Males do not form copulatory mating plug.
C_elegans_phenotype_ontology
mating plug minus
plug minus
WBPhenotype:0001730
mating plug deficient
Males do not form copulatory mating plug.
WB:WBPaper00002770
WB:WBPerson712
Animals exhibit variations in the duration of the trajectory of the forward track in a thermal gradient compared to control.
thermal bias in tracking abnormal
C_elegans_phenotype_ontology
cryophilic bias
WBPhenotype:0001731
thermal bias in tracking variant
Animals exhibit variations in the duration of the trajectory of the forward track in a thermal gradient compared to control.
WB:WBPaper00032070
WB:WBPerson712
Animals exhibit variations in their response and ability to survive over a range of pH conditions compared to control.
organism response to pH abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001732
organism response to pH variant
Animals exhibit variations in their response and ability to survive over a range of pH conditions compared to control.
WB:WBPaper00032033
WB:WBPerson712
Animals treated with pheromone do not exhibit a decrease in pumping rate similar to that observed for control animals.
pheromone suppressed pumping abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001733
pheromone suppressed pumping defective
Animals treated with pheromone do not exhibit a decrease in pumping rate similar to that observed for control animals.
WB:WBPaper00032082
WB:WBPerson712
Animals deprived of food do not exhibit a decrease in pumping rate similar to that observed for control animals.
starvation suppressed pumping abnormal
C_elegans_phenotype_ontology
food deprived suppression of pumping abnormal
WBPhenotype:0001734
starvation suppressed pumping defective
Animals deprived of food do not exhibit a decrease in pumping rate similar to that observed for control animals.
WB:WBPaper00032082
WB:WBPerson712
Animals exhibit variations in the frequency, rate or extent of muscle contraction compared to control animals.
muscle cell activity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001735
muscle cell activity variant
Animals exhibit variations in the frequency, rate or extent of muscle contraction compared to control animals.
GO:0006937
WB:WBPaper00032000
WB:WBPerson712
Failure to execute the characteristic response to acetate compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001736
acetate chemotaxis defective
Failure to execute the characteristic response to acetate compared to control animals.
WB:WBPaper00031959
WB:WBPerson557
WB:WBPerson712
Animals are unable to locate the gradient peak of a water soluble compound, which was generated on a uniform concentration of another compound.
aqueous compound discrimination abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001737
aqueous compound discrimination defective
Animals are unable to locate the gradient peak of a water soluble compound, which was generated on a uniform concentration of another compound.
WB:WBPaper00031959
WB:WBPerson712
Failure to execute the characteristic response to ammonium compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001738
ammonium chemotaxis defective
Failure to execute the characteristic response to ammonium compared to control animals.
WB:WBPaper00031959
WB:WBPerson712
Any variation in an organism's decline over time from its optimal fertility and viability compared to control animals.
aging abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001739
aging variant
Any variation in an organism's decline over time from its optimal fertility and viability compared to control animals.
WB:WBPaper00032067
WB:WBPerson712
Any variation in the preprogrammed process that occurs in an organism that is associated with the dismantling of an organ and an overall decline in metabolic function compared to control animals. This may include variations in the rate or extent of morphological disarray and of the breakdown or organelles, membranes and other cellular components.
organ senescence abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001740
organ senescence variant
Any variation in the preprogrammed process that occurs in an organism that is associated with the dismantling of an organ and an overall decline in metabolic function compared to control animals. This may include variations in the rate or extent of morphological disarray and of the breakdown or organelles, membranes and other cellular components.
GO:0010260
WB:WBPaper00032067
WB:WBPerson712
Males exhibit spicule-muscle seizures leading to inappropriately timed protraction compared to control.
Prc
C_elegans_phenotype_ontology
precocious spicule protraction
protraction constitutive
WBPhenotype:0001741
spontaneous spicule protraction
Males exhibit spicule-muscle seizures leading to inappropriately timed protraction compared to control.
WB:WBPaper00032000
WB:WBPerson712
The endogenous anabolism of any lipid species has been increased compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001742
lipid synthesis increased
The endogenous anabolism of any lipid species has been increased compared to that observed in control animals.
WB:WBPaper00032082
WB:WBPerson712
Any variation in the division of the eukaryotic cell nucleus to produce two daughter nuclei that contain the identical chromosome complement of their mother compared to control.
mitosis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001743
mitosis variant
Any variation in the division of the eukaryotic cell nucleus to produce two daughter nuclei that contain the identical chromosome complement of their mother compared to control.
GO:0000278
WB:WBPerson557
Any variation in the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix compared to control.
cell adhesion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001744
cell adhesion variant
Any variation in the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix compared to control.
GO:0007155
WB:WBPerson557
Any variation in a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control.
adherens junction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001745
adherens junction variant
Any variation in a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control.
GO:0005912
WB:WBPerson557
Any perturbation in the belt-like region of very close contact between the plasma membranes of adjacent cells that results in the complete occlusion of the intercellular space.
zonula occludens abnormal
tight junction abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001746
tight junction defective
Any perturbation in the belt-like region of very close contact between the plasma membranes of adjacent cells that results in the complete occlusion of the intercellular space.
GO:0005923
WB:WBPerson557
Animals exhibit variations in the change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus compared to control.
zinc response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001747
zinc response variant
Animals exhibit variations in the change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus compared to control.
GO:0010043
WB:WBPerson712
The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity.
Pun
C_elegans_phenotype_ontology
WBPhenotype:0001748
pharynx unattached
The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity.
WB:WBPaper00031910
WB:WBPerson712
The toxic response to zinc occurs at a lower concentration or a shorter exposure compared to control animals. In C. elegans hypersensitive animals exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has little or no effect on control worms.
C_elegans_phenotype_ontology
WBPhenotype:0001749
zinc toxicity hypersensitive
The toxic response to zinc occurs at a lower concentration or a shorter exposure compared to control animals. In C. elegans hypersensitive animals exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has little or no effect on control worms.
WB:WBPaper00031911
WB:WBPerson712
Animals fail to exhibit toxicity to the concentration of zinc that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to zinc include delayed development or lethality.
C_elegans_phenotype_ontology
WBPhenotype:0001750
zinc toxicity resistant
Animals fail to exhibit toxicity to the concentration of zinc that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to zinc include delayed development or lethality.
WB:WBPaper00031911
WB:WBPerson712
Animals exhibit increased lethality as a result of exposure to environments with a higher solute concentration than their own internal environment, compared to control.
C_elegans_phenotype_ontology
Hos
hypertonic sensitive
WBPhenotype:0001751
organism hypertonic lethality increased
Animals exhibit increased lethality as a result of exposure to environments with a higher solute concentration than their own internal environment, compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in vesicle-based directed movement of substances into, out of, or within a cell compared to control.
vesicle trafficking abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001752
vesicle trafficking variant
Animals exhibit variations in vesicle-based directed movement of substances into, out of, or within a cell compared to control.
GO:0016192
WB:WBPerson712
Animals exhibit intensified accumulation of fluids or fluorescent markers etc. within their coelomocytes compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001753
coelomocyte uptake increased
Animals exhibit intensified accumulation of fluids or fluorescent markers etc. within their coelomocytes compared to control animals.
WB:WBPaper00004883
WB:WBPerson712
Contents of endosomes fail to be transported to lysosomal compartments.
C_elegans_phenotype_ontology
WBPhenotype:0001754
endosome to lysosome trafficking defective
Contents of endosomes fail to be transported to lysosomal compartments.
WB:WBPaper00029049
WB:WBPerson712
Animals do not arrest mitotic germ cell division, as control animals, when treated with UV radiation.
C_elegans_phenotype_ontology
WBPhenotype:0001755
UV induced mitotic germ cell arrest defective
Animals do not arrest mitotic germ cell division, as control animals, when treated with UV radiation.
WB:WBPaper00028948
WB:WBPerson557
Programmed cell death caused by UV radiation is reduced compared to control animals. In C. elegans, this is often measured in the pachytene region of the gonad.
C_elegans_phenotype_ontology
WBPhenotype:0001756
UV induced apoptosis decreased
Programmed cell death caused by UV radiation is reduced compared to control animals. In C. elegans, this is often measured in the pachytene region of the gonad.
WB:WBPaper00028948
WB:WBPerson557
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of signalling peptides in the organism compared to control.
neuropeptide metabolism abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001757
neuropeptide metabolism variant
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of signalling peptides in the organism compared to control.
WB:WBPerson712
Variations in the chemical reactions and pathways involved in the formation and maturation of specialized peptidergic neurotransmitters encoded as preproproteins that are posttranslationally processed to yield bioactive neuropeptides compared to control (Wormatlas).
neuropeptide processing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001758
neuropeptide processing variant
Variations in the chemical reactions and pathways involved in the formation and maturation of specialized peptidergic neurotransmitters encoded as preproproteins that are posttranslationally processed to yield bioactive neuropeptides compared to control (Wormatlas).
WB:WBPerson2021
WB:WBPerson557
Variations in the biogenesis or stability of the 21U-RNA class of molecules compared to control. Molecules are classified as 21U-RNA based on the presence of a 5'U and a conserved upstream motif, which may specify the production of these molecules, in addition these molecules are typically 21nt in length.
21U RNA expression abnormal
C_elegans_phenotype_ontology
piRNA expression abnormal
WBPhenotype:0001759
21U RNA expression variant
Variations in the biogenesis or stability of the 21U-RNA class of molecules compared to control. Molecules are classified as 21U-RNA based on the presence of a 5'U and a conserved upstream motif, which may specify the production of these molecules, in addition these molecules are typically 21nt in length.
GO:0016070
WB:WBPaper00028915
WB:WBPaper00031962
WB:WBPerson712
Animals exhibit an increase in the rate of deletion events in mono-G or G-rich tracts within the genome compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001760
G tract instability
Animals exhibit an increase in the rate of deletion events in mono-G or G-rich tracts within the genome compared to control.
WB:WBPaper00031945
WB:WBPerson712
Regulated ventral midline crossing by axons vary either in the frequency of crossing events or the maintenance through development of process positions compared to control.
axon midline crossing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001761
axon midline crossing variant
Regulated ventral midline crossing by axons vary either in the frequency of crossing events or the maintenance through development of process positions compared to control.
GO:0016199
WB:WBPaper00032007
WB:WBPerson712
Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom.
C_elegans_phenotype_ontology
WBPhenotype:0001762
uptake of yolk defective
Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom.
WB:WBPaper00003831
WB:WBPerson712
Uptake of subtances from the intestine is altered from that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001763
uptake by intestinal cell defective
Uptake of subtances from the intestine is altered from that observed in control animals.
WB:WBPaper00004883
WB:WBPerson712
Animals exhibit variations in their response to carbon dioxide compared to control.
carbon dioxide response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001764
carbon dioxide response variant
Animals exhibit variations in their response to carbon dioxide compared to control.
WB:WBPerson712
Variations in the characteristic movement away from specific CO2 levels compared to control. C. elegans avoids high levels of CO2.
carbon dioxide avoidance abnormal
C_elegans_phenotype_ontology
CO2 avoidance abnormal
Cdad
WBPhenotype:0001765
carbon dioxide avoidance variant
Variations in the characteristic movement away from specific CO2 levels compared to control. C. elegans avoids high levels of CO2.
WB:WBPaper00031935
WB:WBPerson557
WB:WBPerson712
Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001766
cholesterol depletion hypersensitive
Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals.
GO:0042632
WB:WBPaper00026641
WB:WBPerson557
WB:WBPerson712
Outgrowth of the commissure occurs on the side of the body different from that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001767
commissure handedness defective
Outgrowth of the commissure occurs on the side of the body different from that observed in control animals.
WB:WBPaper00032007
WB:WBPerson712
Variations in the quantity of circumferential axonal tracts from the number observed in control animals.
commissure number abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001768
commissure number variant
Variations in the quantity of circumferential axonal tracts from the number observed in control animals.
WB:WBPaper00032007
WB:WBPerson712
Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi.
C_elegans_phenotype_ontology
WBPhenotype:0001769
cytoplasmic RNAi defective
Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi.
WB:WBPaper00032049
WB:WBPerson712
Animals exhibit variations in their selective interactions with small interfering RNA molecules compared to control.
endo siRNA binding abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001770
endo siRNA binding variant
Animals exhibit variations in their selective interactions with small interfering RNA molecules compared to control.
GO:0035197
WB:WBPaper00032049
WB:WBPerson712
Animals exhibit variations in the length or amount of any endogenous small interfering RNA molecule populations compared to control.
endo siRNA production abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001771
endo siRNA production variant
Animals exhibit variations in the length or amount of any endogenous small interfering RNA molecule populations compared to control.
WB:WBPaper00031932
WB:WBPaper00032049
WB:WBPerson712
Animals exhibit an increase in the levels of transposase mRNA, from endogenous transposons, over that measured in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001772
endogenous transposase levels increased
Animals exhibit an increase in the levels of transposase mRNA, from endogenous transposons, over that measured in control animals.
WB:WBPaper00031962
WB:WBPerson712
Animals do not exhibit an increase in speed when placed in an environment that relies on a combination of swimming and crawling behaviors compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001773
enhanced locomotion defective
Animals do not exhibit an increase in speed when placed in an environment that relies on a combination of swimming and crawling behaviors compared to control.
WB:WBPaper00031965
WB:WBPerson712
An epidermal enclosure defect that results in internal organs lying on the outside of the embryo.
Gex
C_elegans_phenotype_ontology
WBPhenotype:0001774
gut on the exterior
An epidermal enclosure defect that results in internal organs lying on the outside of the embryo.
WB:WBPaper00005123
WB:WBPaper00032090
WB:WBPerson712
Pre-treatment with stress-inducing temperatures does not result in a life-span extension as it does in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001775
hormetic temperature induced life span extension defective
Pre-treatment with stress-inducing temperatures does not result in a life-span extension as it does in control animals.
WB:WBPaper00028750
WB:WBPaper00031942
WB:WBPerson712
Variations in the biogenesis and stability of the small interfering class of RNA molecules compared to control. In C. elegans these molecules are antisense to mRNA's and may be processed from long double-stranded RNA.
siRNA expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001776
siRNA expression variant
Variations in the biogenesis and stability of the small interfering class of RNA molecules compared to control. In C. elegans these molecules are antisense to mRNA's and may be processed from long double-stranded RNA.
GO:0016070
WB:WBPaper00028915
WB:WBPaper00031962
WB:WBPerson712
Animals exhibit an increase in the levels of nuclear mRNA species compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001777
pre mRNA levels increased
Animals exhibit an increase in the levels of nuclear mRNA species compared to control.
WB:WBPaper00032049
WB:WBPerson712
Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus.
C_elegans_phenotype_ontology
WBPhenotype:0001778
nuclear RNAi defective
Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus.
WB:WBPaper00032049
WB:WBPerson712
Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts.
miRNA expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001779
miRNA expression variant
Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts.
GO:0035196
WB:WBPaper00028915
WB:WBPaper00029181
WB:WBPaper00030747
WB:WBPaper00031962
WB:WBPerson712
Variations in the behavioral plasticity induced by the integration of two sensory signals compared to control. In C. elegans animals exhibit enhancement of butanone chemotaxis by preexposure to butanone and food.
C_elegans_phenotype_ontology
WBPhenotype:0001780
associative learning variant
Variations in the behavioral plasticity induced by the integration of two sensory signals compared to control. In C. elegans animals exhibit enhancement of butanone chemotaxis by preexposure to butanone and food.
WB:WBPaper00029060
WB:WBPerson2021
Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality.
C_elegans_phenotype_ontology
WBPhenotype:0001781
hypersensitivity to mutagen
Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality.
WB:WBPaper00031945
WB:WBPerson712
Response to trace levels of oxygen is reduced or weakened compared to the response of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001782
anoxia response attenuated
Response to trace levels of oxygen is reduced or weakened compared to the response of control animals.
WB:WBPaper00031981
WB:WBPerson712
Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals.
ligand gated channel activity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001783
ligand gated channel activity variant
Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals.
GO:0022834
WB:WBPaper00031930
WB:WBPerson712
OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes.
C_elegans_phenotype_ontology
WBPhenotype:0001784
obsolete lysosome homeostasis deficient
true
OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes.
GO:0007040
WB:WBPaper00029049
WB:WBPerson712
Animals are deficient in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms.
C_elegans_phenotype_ontology
WBPhenotype:0001785
associative memory defective
Animals are deficient in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms.
WB:WBPaper00031974
WB:WBPerson712
Animals exhibit variations in the targeting, clustering and or maintenance of ion channels in distinct subcellular domains of the neuron compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001786
neuronal ion channel clustering defective
Animals exhibit variations in the targeting, clustering and or maintenance of ion channels in distinct subcellular domains of the neuron compared to control animals.
GO:0045161
WB:WBPaper00031930
WB:WBPerson712
Animals do not respond via directed movement to light stimuli in the same manner as control animals. In C. elegans, animals move away from light.
C_elegans_phenotype_ontology
WBPhenotype:0001787
phototaxis defective
Animals do not respond via directed movement to light stimuli in the same manner as control animals. In C. elegans, animals move away from light.
WB:WBPaper00031999
WB:WBPerson712
Animals survive longer than control animals after or during exposure to DNA damaging agents.
C_elegans_phenotype_ontology
WBPhenotype:0001788
resistant to mutagens
Animals survive longer than control animals after or during exposure to DNA damaging agents.
WB:WBPaper00031934
WB:WBPerson712
Life span of the animal is not influenced by changes in temperature in the same manner as control animals.
temperature independent life span
temperature influenced life span abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001789
temperature influenced life span variant
Life span of the animal is not influenced by changes in temperature in the same manner as control animals.
WB:WBPaper00031942
WB:WBPerson712
Cooling or warming evoked changes in membrane currents are not observed.
C_elegans_phenotype_ontology
ThRC absent
WBPhenotype:0001790
thermoreceptor currents absent
Cooling or warming evoked changes in membrane currents are not observed.
WB:WBPaper00032060
WB:WBPerson712
Animals exhibit variations in temperature dependent differences in the length of their defecation cycle. In C. elegans the length of the cycle is the same at different temperatures, showing temperature compensation.
defecation cycle temperature compensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001791
defecation cycle temperature compensation variant
Animals exhibit variations in temperature dependent differences in the length of their defecation cycle. In C. elegans the length of the cycle is the same at different temperatures, showing temperature compensation.
WB:WBPaper00002315
WB:WBPerson712
Nuclei of specific cells are smaller compared to control animals.
nuclear size decreased
C_elegans_phenotype_ontology
WBPhenotype:0001792
nuclei small
Nuclei of specific cells are smaller compared to control animals.
WB:WBPerson557
The anterior body contraction and expulsion steps of the defecation cycle are absent; posterior body contractions are still present.
C_elegans_phenotype_ontology
Aex
WBPhenotype:0001793
aboc expulsion missing
The anterior body contraction and expulsion steps of the defecation cycle are absent; posterior body contractions are still present.
WB:WBPaper00002776
WB:WBPerson712
Discrete foci within the cytoplasm containing congregations of mRNA translational suppression and degradation mechanisms vary in their arrangement, clustering or are otherwise not well-defined compared to control.
cytoplasmic processing body abnormal
C_elegans_phenotype_ontology
P body abnormal
WBPhenotype:0001794
cytoplasmic processing body variant
Discrete foci within the cytoplasm containing congregations of mRNA translational suppression and degradation mechanisms vary in their arrangement, clustering or are otherwise not well-defined compared to control.
WB:WBPaper00031914
WB:WBPaper00032172
WB:WBPerson712
Animals exhibit variations in repeat lengths of microsatellite genomic sequences compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001795
microsatellite instability
Animals exhibit variations in repeat lengths of microsatellite genomic sequences compared to control.
WB:WBPaper00031859
WB:WBPerson712
Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin) compared to control. In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to control animals after exposure to the agent.
C_elegans_phenotype_ontology
interstrand cross link agent hypersensitive
WBPhenotype:0001796
organism hypersensitive interstrand cross link agents
Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin) compared to control. In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to control animals after exposure to the agent.
WB:WBPaper00031868
WB:WBPerson712
Germline nuclei do not progress through pachytene to diplotene.
C_elegans_phenotype_ontology
WBPhenotype:0001797
pachytene arrested germline nuclei
Germline nuclei do not progress through pachytene to diplotene.
WB:WBPaper00031914
WB:WBPerson712
The processes that inhibit the location or frequency of formation of synapses are downregulated resulting in the formation of synapses or synapse-like structures in areas of the neuron that are typically devoid of synapses in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001798
inhibition of synaptogenesis defective
The processes that inhibit the location or frequency of formation of synapses are downregulated resulting in the formation of synapses or synapse-like structures in areas of the neuron that are typically devoid of synapses in control animals.
GO:0051964
WB:WBPaper00032163
WB:WBPerson712
The processes that inhibit the location or frequency of formation of synapses are upregulated compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001799
inhibition of synaptogenesis hyperactive
The processes that inhibit the location or frequency of formation of synapses are upregulated compared to control.
GO:0051964
WB:WBPaper00032163
WB:WBPerson712
Changes in the levels of innate immune gene products in response to pathogen exposure are significantly different from that observed in control animals.
antimicrobial gene expression abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001800
pathogen induced antimicrobial gene expression variant
Changes in the levels of innate immune gene products in response to pathogen exposure are significantly different from that observed in control animals.
WB:WBPaper00031865
WB:WBPerson712
Animals fail to establish or maintain characteristics that delineate the dendrite from the axon. The exclusion of presynaptic components from the dendrite is one indication of axodendritic polarity.
axodendritic polarity abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001801
axodendritic polarity variant
Animals fail to establish or maintain characteristics that delineate the dendrite from the axon. The exclusion of presynaptic components from the dendrite is one indication of axodendritic polarity.
WB:WBPaper00032163
WB:WBPerson712
Animals fail to relax their body wall muscles to the same extent as muscles in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001802
body wall muscle relaxation defective
Animals fail to relax their body wall muscles to the same extent as muscles in control animals.
WB:WBPaper00032190
WB:WBPerson712
Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
endosome biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001803
endosome biogenesis variant
Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
WB:WBPaper00032168
WB:WBPerson712
Animals exhibit a decrease in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by decreases in the number of Nile Red or BODIPY 493/503 staining bodies.
C_elegans_phenotype_ontology
lipid body number reduced
WBPhenotype:0001804
fat associated bodies reduced
Animals exhibit a decrease in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by decreases in the number of Nile Red or BODIPY 493/503 staining bodies.
WB:WBPaper00032168
WB:WBPerson712
Inner membrane of mitochondria are disconnected and form vesicular bodies.
C_elegans_phenotype_ontology
WBPhenotype:0001805
mitochondria vesiculated
Inner membrane of mitochondria are disconnected and form vesicular bodies.
GO:0007005
WB:WBPaper00032231
WB:WBPerson712
Any variation in the ability of a protein to resist disintegration via chemical or physical modifications compared to control.
protein stabilization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001806
protein stabilization variant
Any variation in the ability of a protein to resist disintegration via chemical or physical modifications compared to control.
WB:WBPaper00029085
WB:WBPerson2021
Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition compared to control.
alternative splicing abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001807
alternative splicing variant
Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition compared to control.
GO:0000380
WB:WBPerson557
The degradation of genomic and or cellular material of the corpse does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death.
cell corpse digestion abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001808
cell corpse digestion variant
The degradation of genomic and or cellular material of the corpse does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death.
WB:WBPaper00032272
WB:WBPerson712
The formation of mature intracellular compartments via membrane fusion is disrupted.
C_elegans_phenotype_ontology
WBPhenotype:0001809
organelle fusion defective
The formation of mature intracellular compartments via membrane fusion is disrupted.
WB:WBPaper00032272
WB:WBPerson712
Animals exhibit variations in the partitioning of oocytes from each other compared to control animals.
oocyte septum formation abnormal
C_elegans_phenotype_ontology
oocyte cellularization defective
oocyte partition variant
WBPhenotype:0001810
oocyte septum formation variant
Animals exhibit variations in the partitioning of oocytes from each other compared to control animals.
WB:WBPaper00028947
Animals retain a significantly greater proportion of their fat upon serotonin treatment, compared to control.
serotonin induced fat reduction abnormal
C_elegans_phenotype_ontology
serotonin induced fat regulation
WBPhenotype:0001811
serotonin induced fat reduction variant
Animals retain a significantly greater proportion of their fat upon serotonin treatment, compared to control.
WB:WBPaper00031915
WB:WBPerson2021
During development of the embryo, the epidermis loses integrity and the contents of the embryo are expelled.
C_elegans_phenotype_ontology
WBPhenotype:0001812
embryonic rupture
During development of the embryo, the epidermis loses integrity and the contents of the embryo are expelled.
WB:WBPerson557
Animals exhibit defects in the stabilization of homologue pairing, which occurs through the initiation and formation of the synaptonemal complex, during meiosis.
C_elegans_phenotype_ontology
WBPhenotype:0001813
synapsis defective
Animals exhibit defects in the stabilization of homologue pairing, which occurs through the initiation and formation of the synaptonemal complex, during meiosis.
WB:WBPaper00032296
WB:WBPerson712
Animals exhibit defects in the number or extent of connections between chromatids that occur during the process of genetic material exchange between homologous segments of non-sister chromatids.
C_elegans_phenotype_ontology
chiasma defective
homologous recombination foci variant
WBPhenotype:0001814
crossover defective
Animals exhibit defects in the number or extent of connections between chromatids that occur during the process of genetic material exchange between homologous segments of non-sister chromatids.
GO:0051026
WB:WBPaper00032296
WB:WBPerson712
Animals exhibit defects in the asymmetric diassembly of the synaptonemal complex during progression through meiosis.
C_elegans_phenotype_ontology
WBPhenotype:0001815
desynapsis defective
Animals exhibit defects in the asymmetric diassembly of the synaptonemal complex during progression through meiosis.
WB:WBPaper00032296
WB:WBPerson712
Neuromuscular signaling between neurons and egg laying musculature varies from that observed for control animals.
egg laying circuit abnormal
C_elegans_phenotype_ontology
WBPhenotype:0001816
egg laying circuit variant
Neuromuscular signaling between neurons and egg laying musculature varies from that observed for control animals.
WB:WBPaper00032221
WB:WBPerson712
The conditioned aversion to a specific chemical compound as a result of that compound being coupled with an unfavorable condition, such as starvation, does not increase to the same extent as observed for control animals.
C_elegans_phenotype_ontology
enhanced gustatory plasticity defective
enhanced taste aversion defective
starvation enhanced taste aversion defective
WBPhenotype:0001817
enhanced taste aversion defective
The conditioned aversion to a specific chemical compound as a result of that compound being coupled with an unfavorable condition, such as starvation, does not increase to the same extent as observed for control animals.
WB:WBPaper00032335
WB:WBPerson712
Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes.
neuron activation abnormal
C_elegans_phenotype_ontology
neuron activity abnormal
WBPhenotype:0001818
neuron activation variant
Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes.
WB:WBPaper00032221
WB:WBPerson712
The number of pathogens associated with the animal vary from that associated with control animals.
bacterial load variant
C_elegans_phenotype_ontology
WBPhenotype:0001819
pathogen load variant
The number of pathogens associated with the animal vary from that associated with control animals.
WB:WBPaper00032196
WB:WBPerson712
Animals tend to accumulate at the thickest part of the bacterial lawn.
C_elegans_phenotype_ontology
bordering increased
WBPhenotype:0001820
bordering
Animals tend to accumulate at the thickest part of the bacterial lawn.
WB:WBPaper00003187
WB:WBPaper00032342
WB:WBPerson712
Animals do not accumulate at the thickest part of the bacterial lawn. Animals do not preferentially deplete bacterial food at the thicker parts of the lawn.
C_elegans_phenotype_ontology
WBPhenotype:0001821
non bordering
Animals do not accumulate at the thickest part of the bacterial lawn. Animals do not preferentially deplete bacterial food at the thicker parts of the lawn.
WB:WBPaper00032342
WB:WBPerson712
Animals produce pheromone but it does not undergo controlled release into the environment.
C_elegans_phenotype_ontology
WBPhenotype:0001822
dauer pheromone secretion variant
Animals produce pheromone but it does not undergo controlled release into the environment.
WB:WBPaper00032517
WB:WBPerson712
Any variation in the mechanism by which sperm find their correct target destinations (spermatheca).
C_elegans_phenotype_ontology
WBPhenotype:0001823
sperm recruitment variant
Any variation in the mechanism by which sperm find their correct target destinations (spermatheca).
WB:WBPaper00028527
WB:WBPerson2021
Animals exhibit variations in any process necessary for the progression through prophase during meiosis compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001824
meiotic progression prophase variant
Animals exhibit variations in any process necessary for the progression through prophase during meiosis compared to control animals.
WB:WBPaper00005486
WB:WBPerson557
Animals have very few or no germline nuclei and gonad arms that are very small or missing.
C_elegans_phenotype_ontology
WBPhenotype:0001825
rudimentary gonad
Animals have very few or no germline nuclei and gonad arms that are very small or missing.
WB:WBPaper00005486
WB:WBPerson557
Variations in the regulated breakdown of RNA species via the action of cellular enzymes (RNases) compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001826
RNA degradation variant
Variations in the regulated breakdown of RNA species via the action of cellular enzymes (RNases) compared to control.
WB:WBPaper00032091
WB:WBPerson2021
Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001827
RNA metabolism variant
Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control.
WB:WBPaper00004325
WB:WBPerson2021
Variations in the persistence of an RNAi induced phenotype compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001828
RNAi persistence variant
Variations in the persistence of an RNAi induced phenotype compared to control.
WB:WBPaper00004325
WB:WBPerson2021
Any variation that results in the premature differentiation of spermatids into motile spermatozoa compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001829
premature spermatid activation
Any variation that results in the premature differentiation of spermatids into motile spermatozoa compared to control.
WB:WBPaper00033007
WB:WBPerson2021
Any variation in an animal's response to exposure to multiple stressors occuring simultaneously or during an overlapping temporal window compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001830
response to multiple stressors variant
Any variation in an animal's response to exposure to multiple stressors occuring simultaneously or during an overlapping temporal window compared to control.
WB:WBPaper00031874
WB:WBPerson2021
Any variation in the formation of intestinal microvilli. Microvilli are actin-based cellular structures that form plasma membrane projections into the extracellular space and whose specialized shape provides increased cellular surface area. Microvilli are a crucial component of the terminal differentiation process for many epithelial cell types, usually ones that play an absorptive or filtering role.
C_elegans_phenotype_ontology
WBPhenotype:0001831
intestinal microvilli variant
Any variation in the formation of intestinal microvilli. Microvilli are actin-based cellular structures that form plasma membrane projections into the extracellular space and whose specialized shape provides increased cellular surface area. Microvilli are a crucial component of the terminal differentiation process for many epithelial cell types, usually ones that play an absorptive or filtering role.
WB:WBPaper00025171
WB:WBPerson557
Any variation that disrupts the assembly, distribution, localization or organization of any of the numerous similar discrete openings in the nuclear envelope, where the inner and outer nuclear membranes are joined.
C_elegans_phenotype_ontology
WBPhenotype:0001832
nuclear pore variant
Any variation that disrupts the assembly, distribution, localization or organization of any of the numerous similar discrete openings in the nuclear envelope, where the inner and outer nuclear membranes are joined.
GO:0005643
WB:WBPerson557
Any variation in the directed movement of substances in a cell, from one side of a membrane to another, compared to control.
C_elegans_phenotype_ontology
membrane transport variant
transporter activity variant
WBPhenotype:0001833
membrane trafficking variant
Any variation in the directed movement of substances in a cell, from one side of a membrane to another, compared to control.
GO:0005215
WB:WBPaper00025137
WB:WBPerson2021
Variations in the processes regulating the excision of intervening introns from the primary mRNA transcript, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001834
mRNA splicing variant
Variations in the processes regulating the excision of intervening introns from the primary mRNA transcript, compared to control.
GO:0008380
WB:WBPaper00032287
WB:WBPerson2021
Variations in the amount of energy consumed by an organism compared to control. Energy expenditure is often determined by assaying oxygen consumption.
C_elegans_phenotype_ontology
WBPhenotype:0001835
energy expenditure variant
Variations in the amount of energy consumed by an organism compared to control. Energy expenditure is often determined by assaying oxygen consumption.
WB:WBPaper00032936
WB:WBPerson2021
Any variation in the overall structure or appearance of the protective barrier which isolates the embryo from the external environment, compared to control .
C_elegans_phenotype_ontology
WBPhenotype:0001836
eggshell morphology variant
Any variation in the overall structure or appearance of the protective barrier which isolates the embryo from the external environment, compared to control .
WB:WBPaper00033072
WB:WBPerson2021
Life span of the animal is not influenced by changes in diet in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001837
diet induced life span variant
Life span of the animal is not influenced by changes in diet in the same manner as control animals.
WB:WBPaper00032936
WB:WBPerson2021
Gene expression of an animal is not influenced by drug treatment in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001838
drug induced gene expression variant
Gene expression of an animal is not influenced by drug treatment in the same manner as control animals.
WB:WBPaper00033094
WB:WBPerson2021
Animals fail to respond to the concentration of phorbol esters that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Phorbol esters such as PMA act as DAG mimetics.
C_elegans_phenotype_ontology
WBPhenotype:0001839
phorbol ester resistant
Animals fail to respond to the concentration of phorbol esters that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Phorbol esters such as PMA act as DAG mimetics.
WB:WBPaper00033094
WB:WBPerson2021
Variations in the processes that restore integrity to a damaged tissue following an injury, compared to control.
C_elegans_phenotype_ontology
wound healing variant
WBPhenotype:0001840
response to injury variant
Variations in the processes that restore integrity to a damaged tissue following an injury, compared to control.
GO:0042060
WB:WBPaper00033094
WB:WBPerson2021
Any variation in a series of molecular signals that help relay a receptor mediated signal within the cell, compared to control. Second messengers often comprise of ions (eg: Ca2+) or small molecules (cGMP, cAMP etc) that are formed or released into the cytosol.
C_elegans_phenotype_ontology
WBPhenotype:0001841
second messenger mediated signaling variant
Any variation in a series of molecular signals that help relay a receptor mediated signal within the cell, compared to control. Second messengers often comprise of ions (eg: Ca2+) or small molecules (cGMP, cAMP etc) that are formed or released into the cytosol.
GO:0019932
WB:WBPaper00033456
WB:WBPerson2021
Any variation in the state or activity of an organism as a result of abrupt discontinuation or decreased dosage of a drug, compared to control.
C_elegans_phenotype_ontology
rebound response defective
WBPhenotype:0001842
drug withdrawal response variant
Any variation in the state or activity of an organism as a result of abrupt discontinuation or decreased dosage of a drug, compared to control.
WB:WBPaper00033168
WB:WBPerson2021
Animals exhibit variations in any process that involves the degradation, biosynthesis or accumulation of hormones within the organism compared to control. Hormones are naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
C_elegans_phenotype_ontology
WBPhenotype:0001843
hormone metabolism variant
Animals exhibit variations in any process that involves the degradation, biosynthesis or accumulation of hormones within the organism compared to control. Hormones are naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
GO:0042445
WB:WBPaper00034639
WB:WBPerson2021
Variations in the process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids, compared to control.
C_elegans_phenotype_ontology
fat granule regulated breakdown variant
fat granule regulated hydrolysis variant
lipid lysis regulation variant
regulation of lipid catabolic process variant
WBPhenotype:0001844
lipid hydrolysis regulation variant
Variations in the process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids, compared to control.
GO:0050994
WB:WBPaper00033126
WB:WBPerson2021
Variations in the covalent alteration of one or more components (eg: fatty acids, sterols etc.) in a lipid, resulting in a change in the properties of the lipid, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001845
lipid modification variant
Variations in the covalent alteration of one or more components (eg: fatty acids, sterols etc.) in a lipid, resulting in a change in the properties of the lipid, compared to control.
GO:0030258
WB:WBPaper00034639
WB:WBPerson2021
Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes.
C_elegans_phenotype_ontology
WBPhenotype:0001846
phagosome maturation defective
Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes.
GO:0001845
WB:WBPaper00031805
WB:WBPerson2021
Variations in the processes that facilitate/permit dauer entry when exposed to specific sterol molecules, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001847
sterol induced dauer formation variant
Variations in the processes that facilitate/permit dauer entry when exposed to specific sterol molecules, compared to control.
WB:WBPaper00034639
WB:WBPerson2021
Variations in the process by which the anatomical structures of a tube are generated and organized, compared to control. Morphogenesis pertains to the creation of form or shape.
C_elegans_phenotype_ontology
tubulogenesis variant
WBPhenotype:0001848
tube morphogenesis variant
Variations in the process by which the anatomical structures of a tube are generated and organized, compared to control. Morphogenesis pertains to the creation of form or shape.
GO:0035239
WB:WBPaper00033081
WB:WBPerson2021
Variations in the regulation of levels, transport, and metabolism of zinc ions within an organism compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001849
zinc homeostasis variant
Variations in the regulation of levels, transport, and metabolism of zinc ions within an organism compared to control.
GO:0006882
WB:WBPaper00033166
WB:WBPerson2021
Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001850
radiation induced germ cell apoptosis variant
Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals.
WB:WBPaper00032243
WB:WBPaper00032356
WB:WBPerson712
Animals exhibit variations in radiation induced non-apoptotic death of multipotential precursor cells or tissues (clonogens) compared to control. Elimination of clonogens results in normal tissue damage as well as solid-tumor eradication.
C_elegans_phenotype_ontology
WBPhenotype:0001851
radiation induced reproductive cell death variant
Animals exhibit variations in radiation induced non-apoptotic death of multipotential precursor cells or tissues (clonogens) compared to control. Elimination of clonogens results in normal tissue damage as well as solid-tumor eradication.
WB:WBPaper00027700
WB:WBPerson2021
Animals exhibit variations in their response to an agent that destroys or causes the expulsion of parasitic intestinal worms compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001852
antihelmintic response variant
Animals exhibit variations in their response to an agent that destroys or causes the expulsion of parasitic intestinal worms compared to that observed in control animals.
WB:WBPaper00035074
WB:WBPerson2021
Animals exhibit variations in their response to the amino-acetonitrile derivatives (AADs) class of synthetic anthelmintics, compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001853
AAD response variant
Animals exhibit variations in their response to the amino-acetonitrile derivatives (AADs) class of synthetic anthelmintics, compared to that observed in control animals.
WB:WBPaper00035150
WB:WBPerson2021
Animals exhibit variations in their response to the microtubule-depolymerizing drug benomyl, compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001854
benomyl response variant
Animals exhibit variations in their response to the microtubule-depolymerizing drug benomyl, compared to that observed in control animals.
WB:WBPaper00035150
WB:WBPerson2021
Animals fail to respond to the concentration of fluoride ions that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to fluoride ions to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001855
fluoride resistant
Animals fail to respond to the concentration of fluoride ions that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to fluoride ions to elicit the response compared to control animals.
WB:WBPaper00035174
WB:WBPerson2021
Animals exhibit variations in their response to ivermectin, an agonist of glutamate-gated chloride channels, compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001856
ivermectin response variant
Animals exhibit variations in their response to ivermectin, an agonist of glutamate-gated chloride channels, compared to that observed in control animals.
WB:WBPaper00035150
WB:WBPaper00035194
WB:WBPerson2021
Gene expression of an animal is not influenced by the exposure to disease causing agents in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001857
pathogen induced gene expression variant
Gene expression of an animal is not influenced by the exposure to disease causing agents in the same manner as control animals.
WB:WBPaper00035315
WB:WBPerson2021
Animals fail to suppress head oscillations in response to anterior touch. In C. elegans, this behavior is a result of tyraminergic signaling.
C_elegans_phenotype_ontology
Sho
WBPhenotype:0001858
suppression of head oscillations defective
Animals fail to suppress head oscillations in response to anterior touch. In C. elegans, this behavior is a result of tyraminergic signaling.
WB:WBPaper00031692
WB:WBPaper00034683
WB:WBPerson2021
Sho
WB:WBPaper00025096
Any variation in the aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes, compared to control.
C_elegans_phenotype_ontology
DCC localization variant
WBPhenotype:0001859
Possible xp.
Dosage compensation complex assembly variant
Any variation in the aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes, compared to control.
GO:0042714
WB:WBPaper00035328
WB:WBPerson2021
Variations in the directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001860
endocytic recycling defective
Variations in the directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport, compared to control.
GO:0032456
WB:WBPaper00035466
WB:WBPerson2021
Gene expression of an animal is not influenced by environmental changes in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001861
environmental stimuli induced gene expression variant
Gene expression of an animal is not influenced by environmental changes in the same manner as control animals.
WB:WBPaper00035435
WB:WBPerson2021
Variations in the regulation of levels, transport, and metabolism of manganese ions within an organism compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001862
Possible XP.
manganese homeostasis variant
Variations in the regulation of levels, transport, and metabolism of manganese ions within an organism compared to control.
GO:0030026
WB:WBPaper00035485
WB:WBPerson2021
Animals exhibit variations in their response to manganese compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001863
Possible XP.
manganese response variant
Animals exhibit variations in their response to manganese compared to that observed in control animals.
GO:0010042
WB:WBPaper00035485
WB:WBPerson2021
Any variation in the processes that modulate the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001864
Possible XP.
protein transport variant
Any variation in the processes that modulate the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore compared to control.
GO:0051223
WB:WBPaper00035491
WB:WBPerson2021
Variations in the process by which one or more ubiquitin moieties are added to a protein, compared to control.
C_elegans_phenotype_ontology
protein ubiquitylation variant
WBPhenotype:0001865
Possible XP.
protein ubiquitination variant
Variations in the process by which one or more ubiquitin moieties are added to a protein, compared to control.
GO:0016567
WB:WBPaper00035602
WB:WBPerson2021
Animals exhibit a reduction in pathogen accumulation, persistent colonization, and luminal distension of the intestine.
C_elegans_phenotype_ontology
Rpa
WBPhenotype:0001866
reduced pathogen accumulation
Animals exhibit a reduction in pathogen accumulation, persistent colonization, and luminal distension of the intestine.
GO:0009617
GO:0045087
WB:WBPaper00035215
WB:WBPerson2987
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a mitotic cell cycle.
C_elegans_phenotype_ontology
WBPhenotype:0001867
mitotic spindle asters defective early emb
Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a mitotic cell cycle.
WB:WBPaper00032910
WB:WBPerson2987
Cells undergoing meiosis exhibit defects in the overall function or activity of the meiotic spindle.
C_elegans_phenotype_ontology
WBPhenotype:0001868
meiotic spindle defective
Cells undergoing meiosis exhibit defects in the overall function or activity of the meiotic spindle.
WB:WBPaper00032910
WB:WBPerson2987
Cells undergoing meiosis exhibit defects in the positioning of the meiotic spindle.
C_elegans_phenotype_ontology
WBPhenotype:0001869
meiotic spindle positioning defective
Cells undergoing meiosis exhibit defects in the positioning of the meiotic spindle.
WB:WBPaper00032910
WB:WBPerson2987
Cells undergoing meiosis exhibit defects in the rotation of the meiotic spindle.
C_elegans_phenotype_ontology
WBPhenotype:0001870
meiotic spindle rotation defective
Cells undergoing meiosis exhibit defects in the rotation of the meiotic spindle.
WB:WBPaper00032910
WB:WBPerson2987
Life span of the animal is not influenced by drug exposure in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001871
drug induced life span variant
Life span of the animal is not influenced by drug exposure in the same manner as control animals.
WB:WBPaper00035656
WB:WBPerson2021
Locomotion of the animal is not influenced by drug exposure in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001872
drug induced locomotion variant
Locomotion of the animal is not influenced by drug exposure in the same manner as control animals.
WB:WBPaper00035656
WB:WBPerson2021
Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the meiotic spindle, the array of microtubules and associated molecules that serves to move duplicated and/or homologous chromosomes apart.
C_elegans_phenotype_ontology
WBPhenotype:0001873
meiotic spindle assembly defective
Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the meiotic spindle, the array of microtubules and associated molecules that serves to move duplicated and/or homologous chromosomes apart.
WB:WBPaper00032910
WB:WBPerson2987
Any variation in the conjugation of the ubiquitin-like protein Nedd8 to another protein compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001874
Possible XP.
protein neddylation variant
Any variation in the conjugation of the ubiquitin-like protein Nedd8 to another protein compared to control.
GO:0045116
WB:WBPerson2021
WB:WBPerson557
Chromosomal masses fail to fully separate and remained linked during anaphase.
C_elegans_phenotype_ontology
chromosome bridging
lagging chromatin
WBPhenotype:0001875
anaphase bridging
Chromosomal masses fail to fully separate and remained linked during anaphase.
WB:WBPerson2021
WB:WBPerson557
Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome.
C_elegans_phenotype_ontology
WBPhenotype:0001876
centriole biogenesis variant
Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome.
WB:WBPerson2021
WB:WBPerson557
Any variation in the structure, form or composition of the membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001877
nuclear membrane morphology variant
Any variation in the structure, form or composition of the membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated, compared to control.
GO:0005634
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the response to the addition of hydroxyurea compared to that observed in control animals. Hydroxyurea stops DNA from being replicated.
C_elegans_phenotype_ontology
HU response variant
hydroxycarbamide response variant
WBPhenotype:0001878
hydroxyurea response variant
Animals exhibit variations in the response to the addition of hydroxyurea compared to that observed in control animals. Hydroxyurea stops DNA from being replicated.
WB:WBPerson2021
WB:WBPerson557
Animals respond to hydroxyurea at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001879
hydroxyurea hypersensitive
Animals respond to hydroxyurea at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the form, structure or composition of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
C_elegans_phenotype_ontology
WBPhenotype:0001880
endoplasmic reticulum morphology variant
Any variation in the form, structure or composition of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
GO:0005783
WB:WBPaper00025163
WB:WBPerson2987
WB:WBPerson557
Any variation in the normally asymmetric distribution of the endoplasmic reticulum during cell divisions of the early embryo. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
C_elegans_phenotype_ontology
WBPhenotype:0001881
endoplasmic reticulum symmetry variant early emb
Any variation in the normally asymmetric distribution of the endoplasmic reticulum during cell divisions of the early embryo. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
WB:WBPaper00025163
WB:WBPerson2987
Any variation in the number of chromosomes in a cell compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001882
aneuploidy
Any variation in the number of chromosomes in a cell compared to control.
WB:WBPaper00032450
WB:WBPerson2987
Embryos exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
C_elegans_phenotype_ontology
WBPhenotype:0001885
cleavage furrow initiation defective early emb
Embryos exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
WB:WBPaper00024200
WB:WBPerson2987
Embryos exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
C_elegans_phenotype_ontology
WBPhenotype:0001886
cleavage furrow termination defective early emb
Embryos exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
WB:WBPaper00024200
WB:WBPerson2987
Animals execute supernumerary cell divisions during the development of the lateral, alae-producing epithelial cells, resulting in a larger number of these cells than control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001887
excess seam cells
Animals execute supernumerary cell divisions during the development of the lateral, alae-producing epithelial cells, resulting in a larger number of these cells than control animals.
WB:WBPaper00032974
WB:WBPerson2987
Animals exhibit an increase in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by increases in the number of BODIPY 493/503 staining.
C_elegans_phenotype_ontology
lipid body number increased
lipid droplet expansion
WBPhenotype:0001888
fat associated bodies increased
Animals exhibit an increase in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by increases in the number of BODIPY 493/503 staining.
WB:WBPaper00035972
WB:WBPerson2021
Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001889
body wall muscle sarcomere morphology variant
Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control.
GO:0030017
WB:WBPerson557
Any variation in the attachment plaque for thin filaments onto the cell membrane. The dense body in body wall muscles is especially large, indenting far into the cytoplasm to border each sarcomere, thus providing a long row of coherent attachment sites at regular intervals (WormAtlas).
C_elegans_phenotype_ontology
WBPhenotype:0001890
body wall muscle dense body variant
Any variation in the attachment plaque for thin filaments onto the cell membrane. The dense body in body wall muscles is especially large, indenting far into the cytoplasm to border each sarcomere, thus providing a long row of coherent attachment sites at regular intervals (WormAtlas).
WB:WBPerson557
Animals exhibit variations in the form, structure or composition of a planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0001891
M line variant
Animals exhibit variations in the form, structure or composition of a planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas).
WB:WBPerson557
Any variation in the levels of the polymerized form of glucose throughout the body of the animal as compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0001892
glycogen levels variant
Any variation in the levels of the polymerized form of glucose throughout the body of the animal as compared to controls.
WB:WBPaper00033086
WB:WBPerson2987
Any reduction in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001893
mitochondrial membrane potential reduced
Any reduction in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control.
WB:WBPaper00033162
WB:WBPerson2987
Animals exhibit variations in the number of nuclei contained in a particular cell type compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001894
nuclear number variant
Animals exhibit variations in the number of nuclei contained in a particular cell type compared to control.
WB:WBPaper00033438
WB:WBPerson2987
Parental chromosomes fail to undergo appropriate mixing upon pronuclear fusion resulting in a zygotic nucleus in which parental genomes remain segregated.
C_elegans_phenotype_ontology
pronuclear fusion defective
WBPhenotype:0001895
parental chromosome mixing defective
Parental chromosomes fail to undergo appropriate mixing upon pronuclear fusion resulting in a zygotic nucleus in which parental genomes remain segregated.
GO:0007344
WB:WBPerson2987
Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001896
gamma ray induced apoptosis decreased
Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control.
WB:WBPaper00036343
WB:WBPerson2021
Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus (electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light) compared to control.
C_elegans_phenotype_ontology
Lite
WBPhenotype:0001897
light response variant
Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus (electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light) compared to control.
GO:0009416
WB:WBPaper00032087
WB:WBPerson2021
Variations in the process by which sister chromatids, identical chromosomes resulting from DNA replication, are physically separated during the meiotic cell cycle, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001898
meiotic sister chromatid segregation variant
Variations in the process by which sister chromatids, identical chromosomes resulting from DNA replication, are physically separated during the meiotic cell cycle, compared to control.
WB:WBPaper00034684
WB:WBPerson2987
Animals exhibit variations in the amount of glutathione compared to control animals at a defined stage. Glutathione, the tripeptide glutamylcysteinylglycine, acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
C_elegans_phenotype_ontology
WBPhenotype:0001899
glutathione levels variant
Animals exhibit variations in the amount of glutathione compared to control animals at a defined stage. Glutathione, the tripeptide glutamylcysteinylglycine, acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
GO:0006749
WB:WBPerson557
Animals exhibit a decrease in the cellular levels of reduced glutathione (GSH), compared to control. Reduced levels of GSH may be an indication of susceptibility to oxidative stress.
C_elegans_phenotype_ontology
reduced levels of GSH
WBPhenotype:0001900
reduced levels of reduced glutathione
Animals exhibit a decrease in the cellular levels of reduced glutathione (GSH), compared to control. Reduced levels of GSH may be an indication of susceptibility to oxidative stress.
WB:WBPaper00034717
WB:WBPerson2987
Animals exhibit variations in the formation or disassembly of fat containing organelles compared to control.
C_elegans_phenotype_ontology
lipid body variant
WBPhenotype:0001901
fat associated bodies variant
Animals exhibit variations in the formation or disassembly of fat containing organelles compared to control.
WB:WBPerson557
Animals exhibit an increase in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining.
C_elegans_phenotype_ontology
lipid body size increased
WBPhenotype:0001902
fat associated body size increased
Animals exhibit an increase in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining.
WB:WBPaper00034742
WB:WBPerson2987
Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression.
C_elegans_phenotype_ontology
WBPhenotype:0001903
centrosome biogenesis variant
Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression.
WB:WBPerson557
Animals fail to exhibit toxicity to the concentration of manganese that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to manganese include dopamine (DA) neuron neurodegeneration.
C_elegans_phenotype_ontology
WBPhenotype:0001904
manganese toxicity resistant
Animals fail to exhibit toxicity to the concentration of manganese that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to manganese include dopamine (DA) neuron neurodegeneration.
WB:WBPaper00035259
WB:WBPerson557
Animals lay fewer total number of eggs over the lifetime of the animal.
C_elegans_phenotype_ontology
WBPhenotype:0001905
fewer eggs laid
Animals lay fewer total number of eggs over the lifetime of the animal.
WB:WBPaper00035252
WB:WBPerson2987
During epidermal morphogenesis, hypodermal cells do not properly undergo the characteristic cell shape changes necessary for the embryo to elongate.
C_elegans_phenotype_ontology
WBPhenotype:0001906
hypodermal cell elongation defective
During epidermal morphogenesis, hypodermal cells do not properly undergo the characteristic cell shape changes necessary for the embryo to elongate.
WB:WBPaper00003991
WB:WBPerson712
Animals exhibit defects in the generation of the dorsal epithelial sheet, which entails distinct cell shape changes and movements to affect the interdigitation of two rows of dorsal cells resulting in a single row of cells across the dorsal midline.
C_elegans_phenotype_ontology
WBPhenotype:0001907
dorsal intercalation defective
Animals exhibit defects in the generation of the dorsal epithelial sheet, which entails distinct cell shape changes and movements to affect the interdigitation of two rows of dorsal cells resulting in a single row of cells across the dorsal midline.
WB:WBPaper00003991
WB:WBPerson712
The animal displays defects in any step of the ventral enclosure process resulting an embryo that is not enclosed and or with interior cells protruding out of the embryo.
C_elegans_phenotype_ontology
WBPhenotype:0001908
ventral closure defective
The animal displays defects in any step of the ventral enclosure process resulting an embryo that is not enclosed and or with interior cells protruding out of the embryo.
WB:WBPaper00003991
WB:WBPerson712
OBSOLETE. Any variation in the prevention of mRNA translation that normally occurs in certain cells, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001909
obsolete translational repression variant
true
OBSOLETE. Any variation in the prevention of mRNA translation that normally occurs in certain cells, compared to control.
WB:WBPerson557
Animals exhibit variations in the assembly, arrangement, orientation, or disassembly of the kinetochore, a multisubunit protein complex on chromosomes where the spindle fibers attach during cell division to pull the chromosomes apart.
C_elegans_phenotype_ontology
WBPhenotype:0001910
Possible XP.
kinetochore organization variant
Animals exhibit variations in the assembly, arrangement, orientation, or disassembly of the kinetochore, a multisubunit protein complex on chromosomes where the spindle fibers attach during cell division to pull the chromosomes apart.
GO:0051383
WB:WBPaper00035270
WB:WBPerson557
Animals do not regrow axons following axon loss or damage, to the same extent, or in the same manner as observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001911
axon regeneration defective
Animals do not regrow axons following axon loss or damage, to the same extent, or in the same manner as observed in control animals.
WB:WBPerson557
WB:WBPerson712
The number of coelomocytes are reduced compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds.
C_elegans_phenotype_ontology
WBPhenotype:0001912
fewer coelomocytes
The number of coelomocytes are reduced compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds.
WB:WBPaper00035290
WB:WBPerson2987
The number of coelomocytes are increased compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds.
C_elegans_phenotype_ontology
WBPhenotype:0001913
excess coelomocytes
The number of coelomocytes are increased compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds.
WB:WBPaper00035290
WB:WBPerson2987
Animals contain fewer pharyngeal cells compared to control animals. In C. elegans, pharyngeal cells are derived from MS-blastomere.
C_elegans_phenotype_ontology
WBPhenotype:0001914
fewer pharyngeal cells
Animals contain fewer pharyngeal cells compared to control animals. In C. elegans, pharyngeal cells are derived from MS-blastomere.
WB:WBPaper00035290
WB:WBPerson2987
Any variation that results in the cellular expression of an mRNA in cells/tissues, that is otherwise not observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001915
mRNA expression ectopic
Any variation that results in the cellular expression of an mRNA in cells/tissues, that is otherwise not observed in control animals.
WB:WBPaper00035290
WB:WBPerson2987
Pathogens internally associated with the animal exhibit an increase in survival compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001916
increased pathogen survival
Pathogens internally associated with the animal exhibit an increase in survival compared to control animals.
WB:WBPaper00035289
WB:WBPerson2987
Variations in the processes that incorporate acetyl groups to one or more amino acids within a protein, compared to control. An acetyl group is CH3CO-.
C_elegans_phenotype_ontology
WBPhenotype:0001917
protein acetylation variant
Variations in the processes that incorporate acetyl groups to one or more amino acids within a protein, compared to control. An acetyl group is CH3CO-.
GO:0006473
WB:WBPaper00025192
WB:WBPerson557
Animals respond to a specific chemical at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001918
chemical hypersensitive
Animals respond to a specific chemical at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals exhibit larger inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0001919
gut granules enlarged
Animals exhibit larger inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
WB:WBPaper00035924
WB:WBPerson2987
The growth of pharyngeal components occurs in a radial fashion around the longitudinal axis of the worm as demonstrated by bent radial contractile arrays within the pharyngeal muscle cells. The defect is more pronounced as development progresses resulting in a more obvious twisting phenotype. Depending on the allele, the twist can be right-handed or left-handed
C_elegans_phenotype_ontology
Twp
pharynx twisted
WBPhenotype:0001920
twisted pharynx
The growth of pharyngeal components occurs in a radial fashion around the longitudinal axis of the worm as demonstrated by bent radial contractile arrays within the pharyngeal muscle cells. The defect is more pronounced as development progresses resulting in a more obvious twisting phenotype. Depending on the allele, the twist can be right-handed or left-handed
WB:WBPaper00030736
WB:WBPerson712
Any variation in the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination.
C_elegans_phenotype_ontology
WBPhenotype:0001921
Possible XP.
meiotic DNA double strand break formation variant
Any variation in the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination.
GO:0042138
WB:WBPerson557
Any variation in the directed movement of organelles or molecules along microtubules in nerve cell axons.
axon transport variant
C_elegans_phenotype_ontology
axon cargo transport variant
WBPhenotype:0001922
Possible XP.
axonal transport variant
Any variation in the directed movement of organelles or molecules along microtubules in nerve cell axons.
GO:0008088
WB:WBPerson557
The population of the lateral, alae-producing epithelial cells (seam cells) is reduced compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001923
fewer seam cells
The population of the lateral, alae-producing epithelial cells (seam cells) is reduced compared to control animals.
WB:WBPaper00034768
Oocytes are found one on top of the other in the dorsal to ventral orientation in the gonad.
C_elegans_phenotype_ontology
WBPhenotype:0001924
oocytes stacked
Oocytes are found one on top of the other in the dorsal to ventral orientation in the gonad.
WB:WBPerson557
Oocytes are no longer arranged in the gonad in the same manner as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001925
oocytes disorganized
Oocytes are no longer arranged in the gonad in the same manner as control animals.
WB:WBPerson557
Basal contraction rate and or peak contraction rate of the gonadal sheath is increased relative to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001926
gonad sheath contraction rate increased
Basal contraction rate and or peak contraction rate of the gonadal sheath is increased relative to control animals.
WB:WBPaper00027739
WB:WBPerson2987
Animals produce an excess number of distal tip cells compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0001927
extra distal tip cells
Animals produce an excess number of distal tip cells compared to controls.
WB:WBPaper00033102
WB:WBPerson2987
Animals produce an excess number of gonad arms compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0001928
extra gonad arms
Animals produce an excess number of gonad arms compared to controls.
WB:WBPaper00033102
WB:WBPerson2987
The gonads of male animals do not produce the linker cell involved in guiding the developing male gonad to the sex organs in the male tail.
C_elegans_phenotype_ontology
WBPhenotype:0001929
linker cell absent
The gonads of male animals do not produce the linker cell involved in guiding the developing male gonad to the sex organs in the male tail.
WB:WBPaper00033102
WB:WBPerson2987
Animals extend altered or fewer numbers of dorsal and or ventral muscle arms compared to control animals.
C_elegans_phenotype_ontology
Madd
muscle arm extension defective
WBPhenotype:0001930
muscle arm development defective
Animals extend altered or fewer numbers of dorsal and or ventral muscle arms compared to control animals.
WB:WBPaper00032907
WB:WBPerson712
The morphology or number of connections between muscle arms and commissural motor axons varies from control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001931
muscle arm axon connection variant
The morphology or number of connections between muscle arms and commissural motor axons varies from control animals.
WB:WBPaper00032907
WB:WBPerson712
Animals exhibit ectopic plasma membrane extensions from muscle, these extensions are random projections that are thinner than the typical muscle arm.
C_elegans_phenotype_ontology
WBPhenotype:0001932
myopodia present
Animals exhibit ectopic plasma membrane extensions from muscle, these extensions are random projections that are thinner than the typical muscle arm.
WB:WBPaper00032907
WB:WBPerson712
The pattern of localization of presynaptic markers is disrupted compared to control animals.
C_elegans_phenotype_ontology
Sam
WBPhenotype:0001933
synaptic vesicle tag abnormal in mechanosensory neurons
The pattern of localization of presynaptic markers is disrupted compared to control animals.
WB:WBPaper00035070
WB:WBPerson712
Any variation in the extension of vulval muscles compared to control. In C. elegans contralateral vulval muscles fail to meet at the midline.
C_elegans_phenotype_ontology
Vme
WBPhenotype:0001934
vulval muscle extension variant
Any variation in the extension of vulval muscles compared to control. In C. elegans contralateral vulval muscles fail to meet at the midline.
WB:WBPaper00036485
WB:WBPerson712
Animals become paralyzed in response to aggregation of proteins like poly-glutamine or beta-amyloid.
C_elegans_phenotype_ontology
WBPhenotype:0001935
protein aggregation induced paralysis
Animals become paralyzed in response to aggregation of proteins like poly-glutamine or beta-amyloid.
WB:WBPaper00033115
WB:WBPerson2987
Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001936
resistant to protein aggregation induced paralysis
Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals.
WB:WBPaper00033115
WB:WBPerson2987
Animals respond to protein aggregation at a lower concentration of aggregates or in less time compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001937
hypersensitive to protein aggregation induced paralysis
Animals respond to protein aggregation at a lower concentration of aggregates or in less time compared to control animals.
WB:WBPaper00033115
WB:WBPerson2987
Any variation in the process of restoring DNA after damage. DNA damage can be caused by a many chemical or physical agents, and this damage is repaired by a variety of different DNA repair pathways.
C_elegans_phenotype_ontology
WBPhenotype:0001938
DNA repair variant
Any variation in the process of restoring DNA after damage. DNA damage can be caused by a many chemical or physical agents, and this damage is repaired by a variety of different DNA repair pathways.
GO:0006281
WB:WBPerson557
Animals are not repelled by bitter tastants such as quinine, primaquine quinacrine etc., to the same extent as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001939
bitter tastant response variant
Animals are not repelled by bitter tastants such as quinine, primaquine quinacrine etc., to the same extent as control animals.
WB:WBPaper00035961
WB:WBPerson712
Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis.
C_elegans_phenotype_ontology
rachis morphology abnormal
WBPhenotype:0001940
rachis morphology variant
Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis.
WB:WBPaper00031889
WB:WBPerson557
The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001941
rachis narrow
The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals.
WB:WBPaper00038381
WB:WBPerson557
The nucleus-free core of germline cytoplasm in the gonad is missing.
C_elegans_phenotype_ontology
WBPhenotype:0001942
rachis absent
The nucleus-free core of germline cytoplasm in the gonad is missing.
WB:WBPaper00038381
WB:WBPerson557
The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001943
rachis wide
The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals.
WB:WBPaper00038381
WB:WBPerson557
A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control.
C_elegans_phenotype_ontology
fewer oocytes
WBPhenotype:0001944
oocyte number decreased
A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control.
WB:WBPaper00038381
WB:WBPerson557
The size of haploid female germ cells (oocytes) are significantly smaller compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001945
oocytes small
The size of haploid female germ cells (oocytes) are significantly smaller compared to control.
WB:WBPaper00038381
WB:WBPerson557
Developing oocytes show defects in their entry, progression through or exit from the pachytene stage compared to control animals. Pachytene is a cell cycle process comprising the steps by which a cell progresses through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.
C_elegans_phenotype_ontology
WBPhenotype:0001946
pachytene progression during oogenesis variant
Developing oocytes show defects in their entry, progression through or exit from the pachytene stage compared to control animals. Pachytene is a cell cycle process comprising the steps by which a cell progresses through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.
GO:0000239
WB:WBPaper00038381
WB:WBPerson557
Developing oocytes show defects in their entry, progression through or exit from the diplotene stage compared to control animals. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
C_elegans_phenotype_ontology
WBPhenotype:0001947
diplotene progression during oogenesis variant
Developing oocytes show defects in their entry, progression through or exit from the diplotene stage compared to control animals. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
GO:0000240
WB:WBPaper00038381
WB:WBPerson557
Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I.
C_elegans_phenotype_ontology
WBPhenotype:0001948
diakinesis progression during oogenesis variant
Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I.
GO:0000241
WB:WBPaper00038381
WB:WBPerson557
Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diakinesis stage. In C. elegans the diakinesis region occurs in the proximal gonad arm and is preceded by the diplotene region. In the diakinesis region oocytes arrest until oocyte maturation occurs.
C_elegans_phenotype_ontology
WBPhenotype:0001949
diakinesis region organization variant
Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diakinesis stage. In C. elegans the diakinesis region occurs in the proximal gonad arm and is preceded by the diplotene region. In the diakinesis region oocytes arrest until oocyte maturation occurs.
WB:WBPaper00038381
WB:WBPerson557
Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file.
C_elegans_phenotype_ontology
WBPhenotype:0001950
diplotene region organization variant
Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file.
WB:WBPaper00038381
WB:WBPerson557
Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas).
C_elegans_phenotype_ontology
WBPhenotype:0001951
pachytene region organization variant
Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas).
WB:WBPaper00038381
WB:WBPerson557
Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control.
C_elegans_phenotype_ontology
germline nuclear migration variant
WBPhenotype:0001952
germline nuclear positioning variant
Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control.
WB:WBPaper00038381
WB:WBPerson557
Nuclei have fallen out of developing germ cell compartments into the rachis.
C_elegans_phenotype_ontology
WBPhenotype:0001953
nuclear fallout
Nuclei have fallen out of developing germ cell compartments into the rachis.
WB:WBPaper00038381
WB:WBPerson557
The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
C_elegans_phenotype_ontology
WBPhenotype:0001954
diplotene absent during oogenesis
The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
GO:0000240
WB:WBPaper00038381
WB:WBPerson557
Haploid female germ cells (oocytes) contain more than one nucleus.
C_elegans_phenotype_ontology
multinucleate oocyte
WBPhenotype:0001955
multiple nuclei oocyte
Haploid female germ cells (oocytes) contain more than one nucleus.
WB:WBPaper00038381
WB:WBPerson557
Haploid female germ cells (oocytes) lack a nucleus.
C_elegans_phenotype_ontology
anucleate oocytes
WBPhenotype:0001956
oocytes lack nucleus
Haploid female germ cells (oocytes) lack a nucleus.
WB:WBPaper00038381
WB:WBPerson557
A decrease in size of the specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0001957
gonad small
A decrease in size of the specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
WB:WBPaper00038381
WB:WBPerson557
Animals contain a gonad that initially functioned, but subsequently stopped. In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus.
C_elegans_phenotype_ontology
degenerate gonad
WBPhenotype:0001958
gonad degenerate
Animals contain a gonad that initially functioned, but subsequently stopped. In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus.
WB:WBPaper00038381
WB:WBPerson557
Pulling forces on the astral microtubules at the spindle poles vary from that observed for control spindles.
C_elegans_phenotype_ontology
WBPhenotype:0001959
spindle pole pulling force variant
Pulling forces on the astral microtubules at the spindle poles vary from that observed for control spindles.
WB:WBPaper00031928
WB:WBPerson712
The spindle in the early embryo is aberrant in the characteristic posterior aster oscillations that occur along the transverse longitudinal axis of the spindle.
C_elegans_phenotype_ontology
WBPhenotype:0001960
spindle oscillation variant
The spindle in the early embryo is aberrant in the characteristic posterior aster oscillations that occur along the transverse longitudinal axis of the spindle.
WB:WBPaper00031928
WB:WBPerson712
Animals continue to produce progeny significantly past the time reproduction stops in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001961
reproductive longevity extended
Animals continue to produce progeny significantly past the time reproduction stops in control animals.
WB:WBPaper00031688
WB:WBPerson712
Animals produce less distal tip cells compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0001962
missing distal tip cells
Animals produce less distal tip cells compared to controls.
WB:WBPaper00026603
WB:WBPerson557
WB:WBPerson712
The association of homologs during diakinesis and the maintenance of their association through meiosis I as well as the preservation of centromeric cohesin between sister chromatids does not proceed as it does in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001963
homolog association variant
The association of homologs during diakinesis and the maintenance of their association through meiosis I as well as the preservation of centromeric cohesin between sister chromatids does not proceed as it does in control animals.
WB:WBPaper00032269
WB:WBPerson712
Animals exhibit differential regulation of the dopaminergic fate among the various classes of dopaminergic neurons.
C_elegans_phenotype_ontology
Dopy
WBPhenotype:0001964
dopaminergic fate atypical
Animals exhibit differential regulation of the dopaminergic fate among the various classes of dopaminergic neurons.
WB:WBPaper00032147
WB:WBPaper00036201
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of the cell, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001965
cell membrane physiology variant
Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of the cell, compared to control animals.
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of within the cell, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001966
cell endomembrane physiology variant
Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of within the cell, compared to control animals.
WB:WBPaper00037899
WB:WBPerson712
Animals differ from control animals in the length of or mechanics of the steps that culminate in the preservation and subsequent disassembly of the synaptonemal complex, the specification of bivalent arms, and proper cohesion of sister chromatids.
C_elegans_phenotype_ontology
WBPhenotype:0001967
meiotic chromatin reorganization variant
Animals differ from control animals in the length of or mechanics of the steps that culminate in the preservation and subsequent disassembly of the synaptonemal complex, the specification of bivalent arms, and proper cohesion of sister chromatids.
WB:WBPaper00032269
WB:WBPerson712
All somatic gonad precursor (SGP) daughters adopt a proximal fate resulting in an increase in the number of AC precursor cells at the expense of distal tip cells (DTC), which are thereby absent.
Sys
C_elegans_phenotype_ontology
symmetrical sisters
WBPhenotype:0001968
somatic gonad precursor symmetrical sisters
All somatic gonad precursor (SGP) daughters adopt a proximal fate resulting in an increase in the number of AC precursor cells at the expense of distal tip cells (DTC), which are thereby absent.
WB:WBPaper00026603
WB:WBPerson712
Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes.
C_elegans_phenotype_ontology
WBPhenotype:0001969
germ cell compartment morphology variant
Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes.
WB:WBPaper00038381
WB:WBPerson557
Germ cell compartments contain an an atypical number on nuclei compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001970
germ cell compartment nuclei number variant
Germ cell compartments contain an an atypical number on nuclei compared to control.
WB:WBPaper00038381
WB:WBPerson557
Germ cell compartments do not contain a nucleus.
C_elegans_phenotype_ontology
WBPhenotype:0001971
germ cell compartment anucleate
Germ cell compartments do not contain a nucleus.
WB:WBPaper00038381
WB:WBPerson557
Germ cell compartments contain multiple nuclei.
C_elegans_phenotype_ontology
WBPhenotype:0001972
germ cell compartment multinucleate
Germ cell compartments contain multiple nuclei.
WB:WBPaper00038381
WB:WBPerson557
Any variation in germ cell compartment size compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001973
germ cell compartment size variant
Any variation in germ cell compartment size compared to control.
WB:WBPaper00038381
WB:WBPerson557
Germ cell compartments are smaller than that of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001974
germ cell compartment small
Germ cell compartments are smaller than that of control animals.
WB:WBPaper00038381
WB:WBPerson557
Germ cell compartments are larger than that of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001975
germ cell compartment large
Germ cell compartments are larger than that of control animals.
WB:WBPaper00038381
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0001976
true
Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001977
germ cell partition morphology variant
Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals.
WB:WBPaper00038381
WB:WBPerson557
Animals lack germ cell partitions (germ cell compartments).
WBPhenotype:0001976
germ cell compartment absent
C_elegans_phenotype_ontology
WBPhenotype:0001978
germ cell partition absent
Animals lack germ cell partitions (germ cell compartments).
WB:WBPaper00038381
WB:WBPerson557
Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad.
C_elegans_phenotype_ontology
WBPhenotype:0001979
gonad vesiculated
Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad.
GO:0031982
WB:WBPaper00038381
WB:WBPerson557
Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes).
C_elegans_phenotype_ontology
WBPhenotype:0001980
germ cell compartment expansion variant
Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes).
WB:WBPaper00038381
WB:WBPerson557
The compartments of the germline do not increase in size.
C_elegans_phenotype_ontology
WBPhenotype:0001981
germ cell compartment expansion absent
The compartments of the germline do not increase in size.
WB:WBPaper00038381
WB:WBPerson557
Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001982
cell membrane organization biogenesis variant
Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WB:WBPaper00038381
WB:WBPerson557
Variation of the time an individual spent on a patch of food (bacterial lawn) before leaving, compared to control animals.
food leaving behavior variant
patch leaving behavior variant
exploratory behavior variant
C_elegans_phenotype_ontology
exploration behavior variant
WBPhenotype:0001983
lawn leaving behavior variant
Variation of the time an individual spent on a patch of food (bacterial lawn) before leaving, compared to control animals.
WB:WBPaper00038234
WB:WBPerson363
Animals exhibit axons with migration behaviors that differ from those observed in control animals after the axons cross a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords.
C_elegans_phenotype_ontology
WBPhenotype:0001984
long range axon migration variant
Animals exhibit axons with migration behaviors that differ from those observed in control animals after the axons cross a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords.
WB:WBPaper00038105
WB:WBPerson712
Animals exhibit axons with migration behaviors that differ from those observed in control animals before the axons reach a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords.
C_elegans_phenotype_ontology
WBPhenotype:0001985
short range axon migration variant
Animals exhibit axons with migration behaviors that differ from those observed in control animals before the axons reach a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords.
WB:WBPaper00038105
WB:WBPerson712
Animals undergo an irreversible high temperature-induced developmental arrest during the first larval stage.
C_elegans_phenotype_ontology
WBPhenotype:0001986
high temperature induced L1 arrest
Animals undergo an irreversible high temperature-induced developmental arrest during the first larval stage.
WB:WBPaper00038168
WB:WBPerson2987
Any variation in the measured levels of acetylcholinesterase (AChE) activity compared to control animals.
acetylcholinesterase class activity variant
C_elegans_phenotype_ontology
WBPhenotype:0001987
acetylcholinesterase activity variant
Any variation in the measured levels of acetylcholinesterase (AChE) activity compared to control animals.
WB:WBPaper00001039
WB:WBPerson712
Animals respond to a detergent at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001988
detergent hypersensitive
Animals respond to a detergent at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00000514
WB:WBPerson712
Animals respond to hypoxic (low oxygen levels) stress after a shorter exposure time compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001989
hypoxia hypersensitive
Animals respond to hypoxic (low oxygen levels) stress after a shorter exposure time compared to control.
WB:WBPerson557
WB:WBPerson712
Animals fail to respond to low amounts of oxygen that elicit a response in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001990
hypoxia resistant
Animals fail to respond to low amounts of oxygen that elicit a response in control animals.
WB:WBPerson557
WB:WBPerson712
Response to low levels of oxygen is reduced or weakened compared to the response of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001991
hypoxia response attenuated
Response to low levels of oxygen is reduced or weakened compared to the response of control animals.
WB:WBPerson557
WB:WBPerson712
Animals exhibit an increase in the number of somatic sheath cells surrounding each gonad arm compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0001992
extra gonadal sheath cells
Animals exhibit an increase in the number of somatic sheath cells surrounding each gonad arm compared to controls.
WB:WBPaper00006209
WB:WBPerson2987
Animals exhibit fewer somatic sheath cells surrounding each gonad arm, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0001993
fewer gonadal sheath cells
Animals exhibit fewer somatic sheath cells surrounding each gonad arm, compared to controls.
WB:WBPaper00006209
WB:WBPerson2987
Any variation in the establishment of left-right asymmetry of the body axis compared to controls.
C_elegans_phenotype_ontology
left right asymmetry variant
WBPhenotype:0001994
left right handedness variant
Any variation in the establishment of left-right asymmetry of the body axis compared to controls.
WB:WBPerson2987
WB:WBPerson557
Cells of the animals exhibit variations in the progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0001995
cell cycle progression variant
Cells of the animals exhibit variations in the progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals.
GO:0007049
WB:WBPerson557
WB:WBPerson712
Any variation in the cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence before entering the S phase, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0001996
cell cycle quiescence variant
Any variation in the cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence before entering the S phase, compared to control.
GO:0070314
WB:WBPerson557
WB:WBPerson712
The nucleus or nuclei are not positioned in a similar manner or pattern in the cell or syncytium to that observed in controls.
C_elegans_phenotype_ontology
WBPhenotype:0001997
nuclear anchoring variant
The nucleus or nuclei are not positioned in a similar manner or pattern in the cell or syncytium to that observed in controls.
WB:WBPaper00003628
WB:WBPerson712
Animals respond more severely to laser ablation than control animals subjected to the same laser ablation conditions.
C_elegans_phenotype_ontology
WBPhenotype:0001998
hypersensitive to laser ablation
Animals respond more severely to laser ablation than control animals subjected to the same laser ablation conditions.
WB:WBPaper00038282
WB:WBPerson712
Animals behave differently from control animals in assays testing for the ability to resolve or respond to conflicting sensory inputs.
C_elegans_phenotype_ontology
WBPhenotype:0001999
conflicting sensory integration variant
Animals behave differently from control animals in assays testing for the ability to resolve or respond to conflicting sensory inputs.
WB:WBPaper00038243
WB:WBPerson712
Animals that exhibit an increase in locomotion activity do not return to basal level locomotion activity at the same rate as that of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002000
recovery from enhanced locomotion variant
Animals that exhibit an increase in locomotion activity do not return to basal level locomotion activity at the same rate as that of control animals.
WB:WBPaper00038487
WB:WBPerson712
The number of synapses per unit area of a neuron differs in the animal compared to that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002001
synapse density variant
The number of synapses per unit area of a neuron differs in the animal compared to that observed for control animals.
WB:WBPaper00039786
WB:WBPerson712
A cell or cell of the animal exhibits extra centrosomes (a subcellular body consisting of two centrioles embedded in a protein matrix) compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002002
supernumerary centrosomes
A cell or cell of the animal exhibits extra centrosomes (a subcellular body consisting of two centrioles embedded in a protein matrix) compared to control.
WB:WBPaper00028464
WB:WBPerson2987
Animals exhibit variations in steady-state levels of hydrogen peroxide (H2O2) compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002003
hydrogen peroxide homeostasis variant
Animals exhibit variations in steady-state levels of hydrogen peroxide (H2O2) compared to control.
WB:WBPaper00040082
WB:WBPerson712
Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002004
actomyosin contractility defective
Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals.
WB:WBPaper00038098
WB:WBPerson712
The tension of the cytoskeleton comprised of the actomyosin network differs from controls. This tension can be measured by laser-cutting of the actomyosin cytoskeleton and observing any differences the recoil velocity of cortex adjacent to the cut site.
C_elegans_phenotype_ontology
WBPhenotype:0002005
actomyosin cytoskeletal tension variant
The tension of the cytoskeleton comprised of the actomyosin network differs from controls. This tension can be measured by laser-cutting of the actomyosin cytoskeleton and observing any differences the recoil velocity of cortex adjacent to the cut site.
WB:WBPaper00038098
WB:WBPerson712
Compared to controls, embryos exhibit variations in the part meiosis I in which homologous chromosomes separate and migrate away from each other.
C_elegans_phenotype_ontology
WBPhenotype:0002006
anaphase I progression variant early embryo
Compared to controls, embryos exhibit variations in the part meiosis I in which homologous chromosomes separate and migrate away from each other.
WB:WBPaper00031064
WB:WBPerson712
Embryos display cortical protusions during cytokinesis.
C_elegans_phenotype_ontology
WBPhenotype:0002007
cortical blebs present
Embryos display cortical protusions during cytokinesis.
WB:WBPaper00038098
WB:WBPerson712
Animals exhibit variations in the non-enzymatic glycosylation process of attaching a protein or lipid to a sugar molecule, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002008
glycation variant
Animals exhibit variations in the non-enzymatic glycosylation process of attaching a protein or lipid to a sugar molecule, compared to control animals.
WB:WBPaper00040082
WB:WBPerson712
Animals exhibit variations from controls in their protein degradation machinery, which functions through the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
C_elegans_phenotype_ontology
WBPhenotype:0002009
proteasome core activity variant
Animals exhibit variations from controls in their protein degradation machinery, which functions through the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0004175
WB:WBPaper00040082
WB:WBPerson712
The dynamics of the replacement of old proteins by newly synthesized or modified proteins varies from that of control animals. This phenotype is often measured by fluorescence recovery after photobleaching (FRAP).
C_elegans_phenotype_ontology
WBPhenotype:0002010
protein turnover variant
The dynamics of the replacement of old proteins by newly synthesized or modified proteins varies from that of control animals. This phenotype is often measured by fluorescence recovery after photobleaching (FRAP).
WB:WBPaper00038098
WB:WBPerson712
Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development.
C_elegans_phenotype_ontology
WBPhenotype:0002011
bivulva
Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development.
WB:WBPaper00040151
WB:WBPerson712
Any variation in the process of chromosome organization that is involved in meiosis, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002012
meiotic chromosome organization variant
Any variation in the process of chromosome organization that is involved in meiosis, compared to control.
GO:0070192
WB:WBPerson557
Chromosomes fails to pair with homologous chromosomes during the prophase stage of meiosis.
C_elegans_phenotype_ontology
WBPhenotype:0002013
univalent meiotic chromosomes
Chromosomes fails to pair with homologous chromosomes during the prophase stage of meiosis.
WB:WBPerson101
WB:WBPerson557
Any observed variation in the measurement of current across the cell membrane compared to measurements in control animals. Current is a flow of electric charge through a medium.
C_elegans_phenotype_ontology
WBPhenotype:0002014
current measurement variant
Any observed variation in the measurement of current across the cell membrane compared to measurements in control animals. Current is a flow of electric charge through a medium.
WB:WBPerson557
Any observed variation in the measurement of voltage across the cell membrane compared to measurements in control animals. Voltage is the difference in electric potential energy per unit charge between two points.
C_elegans_phenotype_ontology
WBPhenotype:0002015
voltage measurement variant
Any observed variation in the measurement of voltage across the cell membrane compared to measurements in control animals. Voltage is the difference in electric potential energy per unit charge between two points.
WB:WBPerson557
Failure to execute the characteristic response to biotin as defined by control animals. In C. elegans, biotin is typically an attractant.
C_elegans_phenotype_ontology
WBPhenotype:0002016
biotin chemotaxis defective
Failure to execute the characteristic response to biotin as defined by control animals. In C. elegans, biotin is typically an attractant.
WB:WBPaper00001481
WB:WBPaper00005801
WB:WBPerson101
WB:WBPerson557
Any variation in the ability of multipotent vulval precursor cells to respond to signals compared to control animals.
C_elegans_phenotype_ontology
vulval precursor cell competence abnormal
vulval precursor cell competence variant
WBPhenotype:0002017
VPC competence variant
Any variation in the ability of multipotent vulval precursor cells to respond to signals compared to control animals.
WB:WBPerson557
Seam cells fuse to form a continuous syncytium along the body wall at a later stage of development compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002018
retarded seam cell fusion
Seam cells fuse to form a continuous syncytium along the body wall at a later stage of development compared to control.
WB:WBPaper00031488
WB:WBPerson2987
Adult animals display a smaller number of eggs inside the uterus compared to controls
C_elegans_phenotype_ontology
WBPhenotype:0002019
fewer eggs in utero
Adult animals display a smaller number of eggs inside the uterus compared to controls
WB:WBPaper00031804
WB:WBPerson2987
Transmission of the signal along the neuron varies from control. This process includes the flow of information from the neuron cell body to the synapse and across to the postsynaptic cell.
C_elegans_phenotype_ontology
WBPhenotype:0002020
transmission of nerve impulse variant
Transmission of the signal along the neuron varies from control. This process includes the flow of information from the neuron cell body to the synapse and across to the postsynaptic cell.
GO:0019226
WB:WBPaper00031592
WB:WBPerson712
Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed at the synapse, which are independent of presynaptic inputs.
C_elegans_phenotype_ontology
WBPhenotype:0002021
synaptic spike frequency variant
Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed at the synapse, which are independent of presynaptic inputs.
WB:WBPaper00031592
WB:WBPerson712
Calcium transients at presynaptic regions do not occur.
C_elegans_phenotype_ontology
WBPhenotype:0002022
no synaptic spike frequency
Calcium transients at presynaptic regions do not occur.
WB:WBPaper00031592
WB:WBPerson712
Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed either at the cell body or the synaptic region, which are independent of presynaptic inputs.
C_elegans_phenotype_ontology
WBPhenotype:0002023
spike frequency variant
Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed either at the cell body or the synaptic region, which are independent of presynaptic inputs.
WB:WBPaper00031592
WB:WBPerson712
Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed in cell bodies, which are independent of presynaptic inputs.
C_elegans_phenotype_ontology
WBPhenotype:0002024
cell body spike frequency variant
Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed in cell bodies, which are independent of presynaptic inputs.
WB:WBPaper00031592
WB:WBPerson712
The diameter, volume, or area taken up by a cell differs from that measured in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002025
cell size decreased
The diameter, volume, or area taken up by a cell differs from that measured in control animals.
WB:WBPaper00038069
WB:WBPerson712
Animals differ from control animals in response to mechanical stimulation targeting different parts of the same cell. In N2 wild-type animals, response to touch near the ALM cell body is reduced compared with touch of the cell area near the second pharyngeal bulb.
C_elegans_phenotype_ontology
WBPhenotype:0002026
differential touch sensitivity variant
Animals differ from control animals in response to mechanical stimulation targeting different parts of the same cell. In N2 wild-type animals, response to touch near the ALM cell body is reduced compared with touch of the cell area near the second pharyngeal bulb.
WB:WBPaper00040149
WB:WBPerson712
VPCs differentiate in the absence of inductive signals coming from the gonad.
Gid
C_elegans_phenotype_ontology
WBPhenotype:0002027
gonad independent vulva differentiation
VPCs differentiate in the absence of inductive signals coming from the gonad.
WB:WBPaper00025001
WB:WBPaper00027764
WB:WBPerson712
Animals differ from controls in their electrical response to mechanical stimulus.
C_elegans_phenotype_ontology
MRC variant
WBPhenotype:0002028
mechanoreceptor current variant
Animals differ from controls in their electrical response to mechanical stimulus.
WB:WBPaper00040149
WB:WBPerson712
Variations in the regulation of levels, transport, and metabolism of metal ions within an organism compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002029
metal homeostasis variant
Variations in the regulation of levels, transport, and metabolism of metal ions within an organism compared to control.
WB:WBPerson712
Variations in the regulation of levels, transport, and metabolism of magnesium ions within an organism compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002030
magnesium homeostasis variant
Variations in the regulation of levels, transport, and metabolism of magnesium ions within an organism compared to control.
GO:0010960
WB:WBPerson557
WB:WBPerson712
Exposure to carbohydrate binding gene products result in an altered action in comparison to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002031
lectin response variant
Exposure to carbohydrate binding gene products result in an altered action in comparison to controls.
WB:WBPaper00038311
WB:WBPerson712
Animals differ from controls in the range, specificity, or presence of targets for exogenously applied lectins.
C_elegans_phenotype_ontology
WBPhenotype:0002032
lectin binding variant
Animals differ from controls in the range, specificity, or presence of targets for exogenously applied lectins.
WB:WBPaper00038311
WB:WBPerson712
Animals contain targets for exogenously applied lectins.
C_elegans_phenotype_ontology
ectopic lectin binding
WBPhenotype:0002033
lectin binding occurs
Animals contain targets for exogenously applied lectins.
WB:WBPaper00038311
WB:WBPerson712
Animals are not observed to contain targets for exogenously applied lectins.
C_elegans_phenotype_ontology
WBPhenotype:0002034
lectin binding does not occur
Animals are not observed to contain targets for exogenously applied lectins.
WB:WBPaper00038311
WB:WBPerson712
Exposure to lectin has no affect on the behavior, growth, or development of the animal compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002035
resistant to lectin
Exposure to lectin has no affect on the behavior, growth, or development of the animal compared to controls.
WB:WBPaper00038311
WB:WBPerson712
Exposure to lectin results in altered behavior, growth, or development of the animal compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002036
susceptible to lectin
Exposure to lectin results in altered behavior, growth, or development of the animal compared to controls.
WB:WBPaper00038311
WB:WBPerson712
The appearance and association of components along the double lipid bilayer enclosing the nucleus differs from controls. The NE separates nuclear contents from the rest of the cytoplasm and includes the intermembrane space, perinuclear space.
C_elegans_phenotype_ontology
WBPhenotype:0002037
nuclear envelope organization variant
The appearance and association of components along the double lipid bilayer enclosing the nucleus differs from controls. The NE separates nuclear contents from the rest of the cytoplasm and includes the intermembrane space, perinuclear space.
WB:WBPaper00040620
WB:WBPerson712
Proteins show defects in their localization in the cilia compared to control animals.
cil
C_elegans_phenotype_ontology
WBPhenotype:0002038
ciliary localization defective
Proteins show defects in their localization in the cilia compared to control animals.
WB:WBPaper00031689
Animals exhibit variation in the directed movement of organelles or molecules along microtubules from the cell periphery in nerve cell axons to the cell body, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002039
retrograde transport variant
Animals exhibit variation in the directed movement of organelles or molecules along microtubules from the cell periphery in nerve cell axons to the cell body, compared to control.
WB:WBPaper00038442
WB:WBPerson712
Chromosomes are not segregated symmetrically during mitosis.
C_elegans_phenotype_ontology
chaotic mitosis
WBPhenotype:0002040
asymmetric chromosome segregation
Chromosomes are not segregated symmetrically during mitosis.
WB:WBPaper00038412
WB:WBPerson712
Animals exhibit variation in timing or ability to molt.
C_elegans_phenotype_ontology
WBPhenotype:0002041
molt variant
Animals exhibit variation in timing or ability to molt.
WB:WBPaper00040467
WB:WBPerson712
Molting cycles do not occur in a temporally controlled manner and cannot be synchronized across a population.
C_elegans_phenotype_ontology
WBPhenotype:0002042
molting arrhythmic
Molting cycles do not occur in a temporally controlled manner and cannot be synchronized across a population.
WB:WBPaper00040467
WB:WBPerson712
The number of cross progeny produced by hermaphrodites is reduced compared to control hermaphrodites.
C_elegans_phenotype_ontology
WBPhenotype:0002043
hermaphrodite mating efficiency reduced
The number of cross progeny produced by hermaphrodites is reduced compared to control hermaphrodites.
WB:WBPerson557
Hermaphrodites do not produce cross progeny.
C_elegans_phenotype_ontology
WBPhenotype:0002044
hermaphrodite mating efficiency eliminated
Hermaphrodites do not produce cross progeny.
WB:WBPerson557
Animals exhibit fewer cell corpses compared to controls at the same developmental life stage.
C_elegans_phenotype_ontology
WBPhenotype:0002045
cell corpse number decreased
Animals exhibit fewer cell corpses compared to controls at the same developmental life stage.
WB:WBPerson712
Variations in the regulation of levels, transport, and metabolism of iron within an organism compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002046
iron homeostasis variant
Variations in the regulation of levels, transport, and metabolism of iron within an organism compared to control.
GO:0055072
WB:WBPerson557
Animals exhibit variations in their response to muscimol compared to that observed in control animals. Muscimol is a GABA-A receptor agonist.
C_elegans_phenotype_ontology
WBPhenotype:0002047
muscimol response variant
Animals exhibit variations in their response to muscimol compared to that observed in control animals. Muscimol is a GABA-A receptor agonist.
WB:WBPaper00038249
WB:WBPerson712
Animals survive longer, or do not respond to the same degree as control animals under similar conditions of abamectin exposure.
C_elegans_phenotype_ontology
WBPhenotype:0002048
abamectin resistant
Animals survive longer, or do not respond to the same degree as control animals under similar conditions of abamectin exposure.
WB:WBPaper00040740
WB:WBPerson557
WB:WBPerson712
Animals are not affected to the same degree as control animals under similar conditions of abamectin exposure.
C_elegans_phenotype_ontology
WBPhenotype:0002049
abamectin repsonse variant
Animals are not affected to the same degree as control animals under similar conditions of abamectin exposure.
WB:WBPaper00040740
WB:WBPerson557
WB:WBPerson712
Animals are do not survive, or become paralyzed in the presence of abamectin.
C_elegans_phenotype_ontology
WBPhenotype:0002050
abamectin sensitive
Animals are do not survive, or become paralyzed in the presence of abamectin.
WB:WBPaper00040740
WB:WBPerson557
WB:WBPerson712
The production or regulation of ascaroside molecule populations differs from that of control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002051
ascaroside biosynthesis variant
The production or regulation of ascaroside molecule populations differs from that of control animals.
WB:WBPaper00040624
WB:WBPerson712
Animals lack the ability to produce ascarosides that are capable of being produced in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002052
ascaroside biosynthesis defective
Animals lack the ability to produce ascarosides that are capable of being produced in control animals.
WB:WBPaper00040624
WB:WBPerson712
Animals fail to respond to or exhibit an attenuated response to ivermectin under conditions that elicits a response in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002053
ivermectin resistant
Animals fail to respond to or exhibit an attenuated response to ivermectin under conditions that elicits a response in control animals.
WB:WBPaper00003945
WB:WBPaper00040740
WB:WBPerson712
Animals exhibit an exaggerated response to magnesium compared to control animals exposed to similar concentrations.
C_elegans_phenotype_ontology
WBPhenotype:0002054
magnesium hypersensitivity
Animals exhibit an exaggerated response to magnesium compared to control animals exposed to similar concentrations.
WB:WBPaper00036046
WB:WBPerson712
Animals do not exhibit light-induced currrents to the same extent or with the same quality as control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002055
photocurrent defective
Animals do not exhibit light-induced currrents to the same extent or with the same quality as control animals.
WB:WBPaper00036207
WB:WBPerson712
Any variation in the specific actions or reactions of an organism causing an alteration in the ingestion of food compared to control animals. In C. elegans the main food source is bacteria and alterations in eating behavior usually lead to malnutrition.
Eat
C_elegans_phenotype_ontology
WBPhenotype:0002056
eating variant
Any variation in the specific actions or reactions of an organism causing an alteration in the ingestion of food compared to control animals. In C. elegans the main food source is bacteria and alterations in eating behavior usually lead to malnutrition.
WB:WBPerson557
WB:WBPerson712
Animals respond to Bacillus thuringiensis toxins (Bt toxins) at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002057
Bacillus thuringiensis toxin hypersensitive
Animals respond to Bacillus thuringiensis toxins (Bt toxins) at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals are not affected to the same degree as control animals under similar conditions of pore forming toxin exposure.
C_elegans_phenotype_ontology
WBPhenotype:0002058
pore forming toxin response variant
Animals are not affected to the same degree as control animals under similar conditions of pore forming toxin exposure.
WB:WBPerson2987
WB:WBPerson557
Animals respond to pore forming toxins at a lower concentration or a shorter exposure compared to control animals. Increased susceptibility to pore forming toxins (e.g. Cry5B from Bacillus thuringiensis) is often measured by a decrease in the rate of survival in the presence of pore forming toxins compared to controls.
Hpo
hypersensitive to pore forming toxin
C_elegans_phenotype_ontology
WBPhenotype:0002059
pore forming toxin hypersensitive
Animals respond to pore forming toxins at a lower concentration or a shorter exposure compared to control animals. Increased susceptibility to pore forming toxins (e.g. Cry5B from Bacillus thuringiensis) is often measured by a decrease in the rate of survival in the presence of pore forming toxins compared to controls.
WB:WBPerson2987
WB:WBPerson557
Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002060
pore forming toxin resistant
Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPerson2987
WB:WBPerson557
Any variation in the progressive decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form.
C_elegans_phenotype_ontology
WBPhenotype:0002061
chromosome decondensation variant
Any variation in the progressive decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form.
GO:0051312
WB:WBPerson2987
WB:WBPerson557
The process of decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form is abolished.
C_elegans_phenotype_ontology
WBPhenotype:0002062
chromosome decondensation failure
The process of decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form is abolished.
WB:WBPerson2987
WB:WBPerson557
Animals differ from controls in the expression of genes targeted for silencing (gene inactivation) in subsequent generations via transcriptional or post-transcriptional processes.
C_elegans_phenotype_ontology
WBPhenotype:0002063
maintenance of gene silencing variant
Animals differ from controls in the expression of genes targeted for silencing (gene inactivation) in subsequent generations via transcriptional or post-transcriptional processes.
GO:0016458
WB:WBPaper00041239
WB:WBPerson557
WB:WBPerson712
Animals express genes that had been targeted for heritable silencing in previous generations.
C_elegans_phenotype_ontology
WBPhenotype:0002064
maintenance of gene silencing defective
Animals express genes that had been targeted for heritable silencing in previous generations.
WB:WBPaper00041239
WB:WBPerson712
Animals display variations in the manner in which the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) is remodeled, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002065
basement membrane remodeling variant
Animals display variations in the manner in which the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) is remodeled, compared to control animals.
WB:WBPaper00038447
WB:WBPerson2987
WB:WBPerson557
Animals display variations in the manner in which an opening in the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) expands to make way for intertissue connections, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002066
basement membrane gap expansion variant
Animals display variations in the manner in which an opening in the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) expands to make way for intertissue connections, compared to control animals.
WB:WBPaper00038447
WB:WBPerson2987
WB:WBPerson557
Animals differ from control animals in cortical actomyocin dynamics leading to internalization of endodermal precursor cells during gastrulation.
C_elegans_phenotype_ontology
WBPhenotype:0002067
apical constriction variant
Animals differ from control animals in cortical actomyocin dynamics leading to internalization of endodermal precursor cells during gastrulation.
WB:WBPaper00040757
WB:WBPerson712
There is significantly less difference between the number of astral microtubles or other component(s) of the spindle microtuble organizing center at the anterior versus posterior poles of the spindle, than observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002068
astral microtubule asymmetry defective
There is significantly less difference between the number of astral microtubles or other component(s) of the spindle microtuble organizing center at the anterior versus posterior poles of the spindle, than observed in control animals.
WB:WBPaper00040200
WB:WBPerson712
Axons in animals do not end in the same manner as they do in control animals. Some defects described include an overextension of the axon or termination of the axon in the shape of a hook, either large or small.
C_elegans_phenotype_ontology
WBPhenotype:0002069
axon termination defective
Axons in animals do not end in the same manner as they do in control animals. Some defects described include an overextension of the axon or termination of the axon in the shape of a hook, either large or small.
WB:WBPaper00040220
WB:WBPerson712
Animals do not mimic control animals in their egg-laying response to muscimol exposure. In C. elegans, muscimol inhibits egg-laying.
C_elegans_phenotype_ontology
WBPhenotype:0002070
egg laying response to muscimol variant
Animals do not mimic control animals in their egg-laying response to muscimol exposure. In C. elegans, muscimol inhibits egg-laying.
WB:WBPaper00038249
WB:WBPerson712
The length of the animal does not increase to the same extent as observed for control animals, in response to exposure to muscimol.
C_elegans_phenotype_ontology
WBPhenotype:0002071
body lengthening response to muscimol variant
The length of the animal does not increase to the same extent as observed for control animals, in response to exposure to muscimol.
WB:WBPaper00038249
WB:WBPerson712
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of carbohydrates within the organism or cell compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002072
carbohydrate metabolism variant
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of carbohydrates within the organism or cell compared to control.
WB:WBPaper00038233
WB:WBPerson557
WB:WBPerson712
Animals exhibit variations in the regulation of levels, transport, and metabolism of cations within a cell or between a cell and its external environment, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002073
cation homeostasis variant
Animals exhibit variations in the regulation of levels, transport, and metabolism of cations within a cell or between a cell and its external environment, compared to control.
WB:WBPaper00036046
WB:WBPerson712
Animals vary in the directed or coordinated movement of their centrosomes during cell division, compared to the pattern of movement observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002074
centrosome dynamics variant
Animals vary in the directed or coordinated movement of their centrosomes during cell division, compared to the pattern of movement observed in control animals.
WB:WBPaper00040172
WB:WBPerson712
Embryos exhibit variations in the processes that lead to the construction of the eggshell, a protective structure that minimizes water loss whilst allowing gas exchanges essential for embryonic respiration, compared to controls
C_elegans_phenotype_ontology
WBPhenotype:0002075
eggshell formation variant
Embryos exhibit variations in the processes that lead to the construction of the eggshell, a protective structure that minimizes water loss whilst allowing gas exchanges essential for embryonic respiration, compared to controls
GO:0030703
WB:WBPaper00031064
WB:WBPaper00040142
WB:WBPerson557
WB:WBPerson712
The process of secretion by a cell that results in the release of intracellular molecules contained within a specialized secretory vesicle that fuses with the plasma membrane during egg activation.
C_elegans_phenotype_ontology
WBPhenotype:0002076
cortical granule exocytosis variant
The process of secretion by a cell that results in the release of intracellular molecules contained within a specialized secretory vesicle that fuses with the plasma membrane during egg activation.
GO:0060471
WB:WBPaper00031064
WB:WBPaper00040142
WB:WBPerson557
WB:WBPerson712
Animals fail to respond to the concentration of a dopamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002077
dopamine resistant
Animals fail to respond to the concentration of a dopamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WB:WBPaper00038270
WB:WBPerson557
WB:WBPerson712
The pattern or state of methyl modifications of histone varies from that of controls.
C_elegans_phenotype_ontology
methylation mark variant
WBPhenotype:0002078
histone methylation variant
The pattern or state of methyl modifications of histone varies from that of controls.
WB:WBPaper00038409
WB:WBPerson712
The animal's ability to reproduce, or start of reproduction occurs later than that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002079
delayed reproductive maturity
The animal's ability to reproduce, or start of reproduction occurs later than that observed for control animals.
WB:WBPerson712
Animals exhibit variations in the degree to which or manner in which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002080
peptide uptake by intestinal cell variant
Animals exhibit variations in the degree to which or manner in which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals.
WB:WBPerson2987
Animals exhibit an increase in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002081
peptide uptake by intestinal cell increased
Animals exhibit an increase in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals.
WB:WBPerson2987
Animals exhibit a decrease in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002082
peptide uptake by intestinal cell decreased
Animals exhibit a decrease in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals.
WB:WBPerson2987
The frequency and distribution of crossover events differs from that observed for controls.
C_elegans_phenotype_ontology
WBPhenotype:0002083
crossover variant
The frequency and distribution of crossover events differs from that observed for controls.
WB:WBPaper00037960
WB:WBPerson712
Animals differ from controls in respect to the frequency of expected double crossover events observed.
C_elegans_phenotype_ontology
WBPhenotype:0002084
crossover interference variant
Animals differ from controls in respect to the frequency of expected double crossover events observed.
WB:WBPaper00037960
WB:WBPerson712
The number of crossover events differs from that of observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002085
crossover formation variant
The number of crossover events differs from that of observed in control animals.
WB:WBPaper00037960
WB:WBPerson712
The location-specific frequency of crossover events differs from that of observed in control animals, while the total number of crossover events does not significantly differ.
C_elegans_phenotype_ontology
WBPhenotype:0002086
crossover distribution variant
The location-specific frequency of crossover events differs from that of observed in control animals, while the total number of crossover events does not significantly differ.
WB:WBPaper00037960
WB:WBPerson712
Animals respond to hydrogen sulfide at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002087
hydrogen sulfide hypersensitive
Animals respond to hydrogen sulfide at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00039977
WB:WBPerson712
Animals respond to dauer pheromone at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002088
hypersensitive to dauer pheromone
Animals respond to dauer pheromone at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson712
Any variation in the form or composition of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles.
C_elegans_phenotype_ontology
WBPhenotype:0002089
cell component morphology variant
Any variation in the form or composition of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002090
endosome morphology variant
Any variation in the form or composition of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002091
late endosome morphology variant
Any variation in the form or composition of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002092
early endosome morphology variant
Any variation in the form or composition of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
C_elegans_phenotype_ontology
WBPhenotype:0002093
recycling endosome morphology variant
Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
C_elegans_phenotype_ontology
WBPhenotype:0002094
RAB-11 recycling endosome morphology variant
Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002095
lysosome-related organelle morphology variant
Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002096
golgi apparatus morphology variant
Any variation in the form or composition of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002097
lysosome morphology variant
Any variation in the form or composition of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles.
C_elegans_phenotype_ontology
WBPhenotype:0002098
cell component localization variant
Any variation in the subcellular localization of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002099
lysosome-related organelle localization variant
Any variation in the subcellular localization of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002100
endosome localization variant
Any variation in the subcellular localization of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that exists in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
C_elegans_phenotype_ontology
WBPhenotype:0002101
endoplasmic reticulum localization variant
Any variation in the subcellular localization of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that exists in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002102
golgi apparatus localization variant
Any variation in the subcellular localization of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002103
lysosome localization variant
Any variation in the subcellular localization of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
C_elegans_phenotype_ontology
WBPhenotype:0002104
recycling endosome localization variant
Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002105
late endosome localization variant
Any variation in the subcellular localization of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002106
early endosome localization variant
Any variation in the subcellular localization of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
C_elegans_phenotype_ontology
WBPhenotype:0002107
RAB-11 recycling endosome localization variant
Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the form or composition of specialized cell types, compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
C_elegans_phenotype_ontology
WBPhenotype:0002108
cell type morphology variant
Any variation in the form or composition of specialized cell types, compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
WB:WBPaper00041129
WB:WBPerson2987
Animals are affected by exposure to the drug.
C_elegans_phenotype_ontology
WBPhenotype:0002109
drug susceptible
Animals are affected by exposure to the drug.
WB:WBPerson712
Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
C_elegans_phenotype_ontology
WBPhenotype:0002110
RME-1 recycling endosome morphology variant
Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WB:WBPaper00041129
WB:WBPerson2987
Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
C_elegans_phenotype_ontology
WBPhenotype:0002111
RME-1 recycling endosome localization variant
Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WB:WBPaper00041129
WB:WBPerson2987
Animals are unable to maintain paired chromosome throughout pachytene.
C_elegans_phenotype_ontology
WBPhenotype:0002112
synapsis maintenance defective
Animals are unable to maintain paired chromosome throughout pachytene.
WB:WBPaper00037960
WB:WBPerson712
Animals differ from controls in respect to the formation of paired chromosome loci.
C_elegans_phenotype_ontology
WBPhenotype:0002113
synapsis formation variant
Animals differ from controls in respect to the formation of paired chromosome loci.
WB:WBPaper00037960
WB:WBPerson712
Animals become paralyzed after a measured amount of time swimming. In C. elegans, more then 80 percent of wild-type animals continue swimming vigorously in liquid even after 30 minutes.
SWIP
C_elegans_phenotype_ontology
WBPhenotype:0002114
swimming induced paralysis
Animals become paralyzed after a measured amount of time swimming. In C. elegans, more then 80 percent of wild-type animals continue swimming vigorously in liquid even after 30 minutes.
WB:WBPaper00038270
WB:WBPerson712
Animals do not avoid, and perhaps seek, environments that result in their death. In the case of C. elegans, this behavior is exemplified by animals that tend to crawl off the plate.
C_elegans_phenotype_ontology
WBPhenotype:0002115
suicidal
Animals do not avoid, and perhaps seek, environments that result in their death. In the case of C. elegans, this behavior is exemplified by animals that tend to crawl off the plate.
WB:WBPerson712
Animals are barely alive, but not entirely dead.
C_elegans_phenotype_ontology
WBPhenotype:0002116
subviable
Animals are barely alive, but not entirely dead.
WB:WBPerson712
Animals exhibit constrictions in the anterior portion of the head that result in decapitation.
C_elegans_phenotype_ontology
WBPhenotype:0002117
occurences of decapitation
Animals exhibit constrictions in the anterior portion of the head that result in decapitation.
WB:WBPerson712
Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations. In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed.
population fitness variant
C_elegans_phenotype_ontology
WBPhenotype:0002118
population fitness phenotype
Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations. In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed.
WB:WBPaper00040316
WB:WBPaper00040815
WB:WBPerson2987
WB:WBPerson557
The process of generating multiple mRNA molecules from differential use of exons in a primary transcript(s) does not occur or occurs with outcomes not observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002119
alternative splicing defective
The process of generating multiple mRNA molecules from differential use of exons in a primary transcript(s) does not occur or occurs with outcomes not observed in control animals.
WB:WBPerson1686
WB:WBPerson712
Any variation in the process of restoring mitochondrial DNA after damage.
C_elegans_phenotype_ontology
WBPhenotype:0002120
mitochondrial DNA repair variant
Any variation in the process of restoring mitochondrial DNA after damage.
GO:0043504
WB:WBPerson557
The presence of a mixture of more than one type of an organellar genome (mitochondrial DNA (mtDNA) or plastid DNA) within a cell or individual.
C_elegans_phenotype_ontology
WBPhenotype:0002121
heteroplasmy
The presence of a mixture of more than one type of an organellar genome (mitochondrial DNA (mtDNA) or plastid DNA) within a cell or individual.
WB:WBPaper00040387
WB:WBPerson2987
Mitochondria from spermatazoa persist in the developing embryo and animal as a result of bypassing the degradation mechanism that normally destroys paternal mitochondria immediately after fertilization. This can often lead to a form of heteroplasmy.
C_elegans_phenotype_ontology
WBPhenotype:0002122
persistence of paternal mitochondria
Mitochondria from spermatazoa persist in the developing embryo and animal as a result of bypassing the degradation mechanism that normally destroys paternal mitochondria immediately after fertilization. This can often lead to a form of heteroplasmy.
WB:WBPaper00040387
WB:WBPerson2987
The pattern or state of acetylation modifications of histones varies from that of controls.
C_elegans_phenotype_ontology
WBPhenotype:0002123
histone acetylation variant
The pattern or state of acetylation modifications of histones varies from that of controls.
WB:WBPaper00040843
WB:WBPerson2987
The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation.
C_elegans_phenotype_ontology
WBPhenotype:0002124
circumferential actin bundles disorganized
The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation.
WB:WBPaper00006290
WB:WBPerson712
Animals do not grow fast or the quality of growth is decreased when exposed to a specific chemical compound when compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002125
growth inhibition response to chemical
Animals do not grow fast or the quality of growth is decreased when exposed to a specific chemical compound when compared to control animals.
WB:WBPaper00040519
WB:WBPerson712
Animals exhibit a decrease in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine.
C_elegans_phenotype_ontology
WBPhenotype:0002126
intestinal fluorescence decreased
Animals exhibit a decrease in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine.
WB:WBPerson712
Animals exhibit variation rate of directed movement of organelles or molecules along microtubules in nerve cell axons, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002127
intraflagellar transport velocity variant
Animals exhibit variation rate of directed movement of organelles or molecules along microtubules in nerve cell axons, compared to control.
WB:WBPaper00038442
WB:WBPerson712
Males remain on food in the absence of mates, a defect in male mate-searching behavior observed in control males.
Las
C_elegans_phenotype_ontology
WBPhenotype:0002128
leaving assay defective
Males remain on food in the absence of mates, a defect in male mate-searching behavior observed in control males.
WB:WBPaper00041718
WB:WBPerson712
Relative levels of mtDNA differ from that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002129
mitochondrial DNA copy number variant
Relative levels of mtDNA differ from that observed for control animals.
WB:WBPaper00032112
WB:WBPerson712
Males exhibit variations of the behaviors observed in control animals that follow the completion of mating.
C_elegans_phenotype_ontology
mate experience variant
WBPhenotype:0002130
post mating variant
Males exhibit variations of the behaviors observed in control animals that follow the completion of mating.
WB:WBPaper00041718
WB:WBPerson712
Animals display variations in the structure or organization of the components of the muscle, compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002131
muscle cell ultrastructure variant
Animals display variations in the structure or organization of the components of the muscle, compared to that observed in control animals.
WB:WBPerson712
The formation, organization, or stability of a protein complex is altered in comparison to corresponding complexes in control animals.
C_elegans_phenotype_ontology
protein clustering variant
WBPhenotype:0002132
protein complex organization variant
The formation, organization, or stability of a protein complex is altered in comparison to corresponding complexes in control animals.
WB:WBPaper00038066
WB:WBPerson712
The bulk flow of cytoplasm in the egg, that facilitates mixing of ooplasm, occurs at a reduced rate compared to that measured for controls.
C_elegans_phenotype_ontology
WBPhenotype:0002133
ooplasmic streaming slow
The bulk flow of cytoplasm in the egg, that facilitates mixing of ooplasm, occurs at a reduced rate compared to that measured for controls.
WB:WBPerson712
Animals are less successful than controls in evading predators during predator-prey interactions.
C_elegans_phenotype_ontology
WBPhenotype:0002134
predator escape defective
Animals are less successful than controls in evading predators during predator-prey interactions.
WB:WBPaper00039982
WB:WBPerson712
Predator-prey interactions differ from that observed in control interactions.
C_elegans_phenotype_ontology
WBPhenotype:0002135
organism predator response variant
Predator-prey interactions differ from that observed in control interactions.
WB:WBPaper00039982
WB:WBPerson712
Animals are missing the anchor cell. In C. elegans the anchor cell is a key organizer of vulval patterning and morphogenesis.
C_elegans_phenotype_ontology
WBPhenotype:0002136
no anchor cell
Animals are missing the anchor cell. In C. elegans the anchor cell is a key organizer of vulval patterning and morphogenesis.
WB:WBPaper00003577
WB:WBPerson2987
WB:WBPerson557
The rate of the process preceding formation of the peptide bond between the first two amino acids of a protein is reduced. This process includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. Increase in free ribosomes (monosomes) are indicative of reduced translation initiation.
C_elegans_phenotype_ontology
WBPhenotype:0002137
reduced translation initiation
The rate of the process preceding formation of the peptide bond between the first two amino acids of a protein is reduced. This process includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. Increase in free ribosomes (monosomes) are indicative of reduced translation initiation.
GO:0006413
WB:WBPaper00039835
WB:WBPerson557
Animals are altered in their capacity to survive a normally lethal temperature treatment as a consequence of pretreatment at an elevated but sublethal temperature.
C_elegans_phenotype_ontology
WBPhenotype:0002138
acquired thermotolerance variant
Animals are altered in their capacity to survive a normally lethal temperature treatment as a consequence of pretreatment at an elevated but sublethal temperature.
WB:WBPaper00040849
WB:WBPerson557
Any variation in the morphological appearance of the linker cell compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002139
linker cell morphology variant
Any variation in the morphological appearance of the linker cell compared to control animals.
WB:WBPaper00035457
WB:WBPerson557
Males do not respond to small molecules or compounds that have been shown to attract control males. This phenotype is often measured by an increase in reversal frequency or time spent in a specified scoring region
C_elegans_phenotype_ontology
WBPhenotype:0002140
male attraction response variant
Males do not respond to small molecules or compounds that have been shown to attract control males. This phenotype is often measured by an increase in reversal frequency or time spent in a specified scoring region
WB:WBPaper00032050
WB:WBPerson712
Variations in the process of gaseous oxygen intake between an organism and its environment compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002141
oxygen consumption variant
Variations in the process of gaseous oxygen intake between an organism and its environment compared to control animals.
WB:WBPaper00042217
WB:WBPerson557
The activity, composition, or organization of the complexes of the electron transport chain, embedded in the inner mitochondrial membrane, differ from controls.
MRC variant
mitochondrial electron transport chain variant
C_elegans_phenotype_ontology
WBPhenotype:0002142
mitochondrial respiratory chain variant
The activity, composition, or organization of the complexes of the electron transport chain, embedded in the inner mitochondrial membrane, differ from controls.
GO:0005746
WB:WBPaper00042217
WB:WBPerson712
The part of the respiratory chain that catalyzes the oxidation of succinate and connects the TCA cycle with the respiratory chain, differs in activity, composition, or organization, from that of controls.
CO II variant
Complex II variant
Succinate dehydrogenase complex variant
C_elegans_phenotype_ontology
WBPhenotype:0002143
mitochondrial respiratory complex II variant
The part of the respiratory chain that catalyzes the oxidation of succinate and connects the TCA cycle with the respiratory chain, differs in activity, composition, or organization, from that of controls.
GO:0045273
WB:WBPaper00042217
WB:WBPerson712
The protein complex located in the mitochondrial inner membrane that is the first entry point for electrons into the electron transport chain and catalyzes proton translocation coupled to the oxidation of NADH by ubiquinone, differs in activity, composition, or organization from that of controls.
CO I variant
Complex I variant
NADH dehydrogenase complex variant
Ubiquinone complex variant
C_elegans_phenotype_ontology
WBPhenotype:0002144
mitochondrial respiratory complex I variant
The protein complex located in the mitochondrial inner membrane that is the first entry point for electrons into the electron transport chain and catalyzes proton translocation coupled to the oxidation of NADH by ubiquinone, differs in activity, composition, or organization from that of controls.
GO:0005747
WB:WBPaper00042217
WB:WBPerson712
Animals are unable to produce or maintain short interfering RNA (siRNA) from double stranded RNA (dsRNA). siRNAs are required to initiate interference of gene expression.
C_elegans_phenotype_ontology
WBPhenotype:0002145
siRNA processing defective
Animals are unable to produce or maintain short interfering RNA (siRNA) from double stranded RNA (dsRNA). siRNAs are required to initiate interference of gene expression.
WB:WBPaper00027057
WB:WBPerson712
Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in the germline. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs).
C_elegans_phenotype_ontology
WBPhenotype:0002146
small RNA germline expression variant
Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in the germline. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs).
WB:WBPaper00027057
WB:WBPerson712
Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in somatic cells. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs).
C_elegans_phenotype_ontology
WBPhenotype:0002147
small RNA somatic expression variant
Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in somatic cells. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs).
WB:WBPaper00027057
WB:WBPerson712
Animals show reduced susceptibility to gene silencing in somatic cells triggered by double stranded RNA (dsRNA), compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002148
somatic RNAi resistant
Animals show reduced susceptibility to gene silencing in somatic cells triggered by double stranded RNA (dsRNA), compared to control.
WB:WBPaper00027057
WB:WBPerson712
Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of the small X-chromosome derived RNAs (X cluster) species of small RNA.
C_elegans_phenotype_ontology
WBPhenotype:0002149
X cluster small RNA expression variant
Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of the small X-chromosome derived RNAs (X cluster) species of small RNA.
WB:WBPaper00027057
WB:WBPerson712
RNAi silencing mechanisms triggered by exogenously introduced (foreign) dsRNA, do not work to the same degree as in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002150
exo-RNAi response variant
RNAi silencing mechanisms triggered by exogenously introduced (foreign) dsRNA, do not work to the same degree as in control animals.
WB:WBPaper00027057
WB:WBPerson712
Animals exhibit variations in the extent to which polyadenylated mRNA transcripts become deadenylated
C_elegans_phenotype_ontology
WBPhenotype:0002151
mRNA deadenylation variant
Animals exhibit variations in the extent to which polyadenylated mRNA transcripts become deadenylated
WB:WBPaper00037823
WB:WBPerson2987
Programmed cell death of germ cells caused by exposure to physical or chemical DNA-damaging agents does not occur to the same extent as it does in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002152
mutagen induced apoptosis variant
Programmed cell death of germ cells caused by exposure to physical or chemical DNA-damaging agents does not occur to the same extent as it does in control animals.
WB:WBPerson712
The production of silencing RNA from dsRNA is significantly deficient compared to controls. Deficiencies in this process can result in a defective RNAi response compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002153
dsRNA processing defective
The production of silencing RNA from dsRNA is significantly deficient compared to controls. Deficiencies in this process can result in a defective RNAi response compared to controls.
WB:WBPaper00029211
WB:WBPerson712
The extent of mRNA ribosome associations varies from controls.
C_elegans_phenotype_ontology
WBPhenotype:0002154
polysome mRNA association variant
The extent of mRNA ribosome associations varies from controls.
WB:WBPaper00032489
WB:WBPerson712
The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002155
pre miRNA processing defective
The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls.
WB:WBPaper00029211
WB:WBPerson712
Wild-type animals will exhibit an altered temperature preference based on food/temperature conditioning. Temperature learning variants do not exhibit altered responses to temperature after conditioning compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002156
temperature learning variant
Wild-type animals will exhibit an altered temperature preference based on food/temperature conditioning. Temperature learning variants do not exhibit altered responses to temperature after conditioning compared to control animals.
WB:WBPaper00031647
WB:WBPerson712
The extent of translational repression varies from controls.
WBPhenotype:0001909
translational repression variant
C_elegans_phenotype_ontology
WBPhenotype:0002157
translation repression variant
The extent of translational repression varies from controls.
WB:WBPaper00032489
WB:WBPerson712
The selective elimination of P granule components and subsequent aggregation of degraded components into PGL granules is disrupted.
C_elegans_phenotype_ontology
WBPhenotype:0002158
P granule degradation defective
The selective elimination of P granule components and subsequent aggregation of degraded components into PGL granules is disrupted.
WB:WBPaper00044350
WB:WBPerson712
Animals exhibit an increase in pathogen accumulation, persistent colonization, and luminal distension of the intestine.
C_elegans_phenotype_ontology
WBPhenotype:0002159
increased pathogen accumulation
Animals exhibit an increase in pathogen accumulation, persistent colonization, and luminal distension of the intestine.
WB:WBPaper00032276
WB:WBPerson2987
The intracellular complex of proteins that participates in bidirectional transport of molecules (cargo) along axonemal microtubules is not made up of or does not maintain the proper number or ratio of components as found in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002160
intraflagellar transport complex destabilized
The intracellular complex of proteins that participates in bidirectional transport of molecules (cargo) along axonemal microtubules is not made up of or does not maintain the proper number or ratio of components as found in control animals.
WB:WBPaper00042072
WB:WBPerson712
Animals exhibit variations from controls in the organization of chromatin, including in relation to associated complexes, that occur during the mitotic cell division cycle.
C_elegans_phenotype_ontology
WBPhenotype:0002161
mitotic chromatin remodeling variant
Animals exhibit variations from controls in the organization of chromatin, including in relation to associated complexes, that occur during the mitotic cell division cycle.
GO:0006338
WB:WBPaper00040620
WB:WBPerson712
Cells exhibit mitotic spindles with more than two poles.
C_elegans_phenotype_ontology
multipolar mitosis
WBPhenotype:0002162
multipolar mitotic spindle
Cells exhibit mitotic spindles with more than two poles.
WB:WBPaper00038412
WB:WBPerson712
Animals exhibit a decreased rate of oxygen utilization compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002163
oxygen consumption decreased
Animals exhibit a decreased rate of oxygen utilization compared to control animals.
WB:WBPaper00036073
WB:WBPerson712
Animals exhibit variations in their defense responses that are mediated by germline encoded components that directly recognize components of potential pathogens.
C_elegans_phenotype_ontology
WBPhenotype:0002164
innate immune response variant
Animals exhibit variations in their defense responses that are mediated by germline encoded components that directly recognize components of potential pathogens.
GO:0045087
WB:WBPerson557
The extent or other quality of the excitatory postsynaptic potential (EPSP) induced by in vitro stimuli differs from that of controls.
C_elegans_phenotype_ontology
WBPhenotype:0002165
muscle excitability variant
The extent or other quality of the excitatory postsynaptic potential (EPSP) induced by in vitro stimuli differs from that of controls.
WB:WBPaper00038066
WB:WBPerson712
The difference in electrical potential between the interior and the exterior of the muscle cell either in the resting state or during evoked stimulation differs from controls.
C_elegans_phenotype_ontology
WBPhenotype:0002166
muscle membrane potential variant
The difference in electrical potential between the interior and the exterior of the muscle cell either in the resting state or during evoked stimulation differs from controls.
WB:WBPaper00039987
WB:WBPerson712
The amount of histone methylation, for example as measured by the amount of H3K4me2, increases over successive generations
C_elegans_phenotype_ontology
generational accumulation of histone methylation
progressive accumulation of histone methylation
transgenerational epigenetic accumulation of histone methylation
WBPhenotype:0002167
transgenerational accumulation of histone methylation
The amount of histone methylation, for example as measured by the amount of H3K4me2, increases over successive generations
WB:WBPaper00045092
WB:WBPerson712
Animals exhibit a decline in fertility over generations. This is often assessed by counting laid eggs over successive generations.
C_elegans_phenotype_ontology
generational loss of fertility
progressive loss of fertility
transgenerational epigenetic loss of fertility
WBPhenotype:0002168
transgenerational loss of fertility
Animals exhibit a decline in fertility over generations. This is often assessed by counting laid eggs over successive generations.
WB:WBPaper00045092
WB:WBPerson712
Animals stop producing progeny significantly before the time reproduction stops in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002169
reproductive longevity shortened
Animals stop producing progeny significantly before the time reproduction stops in control animals.
WB:WBPaper00027157
WB:WBPerson2987
Any variation in the series of molecular signals in which a cell or tissue uses calcium ions to convert a signal into a response, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002170
calcium mediated signaling variant
Any variation in the series of molecular signals in which a cell or tissue uses calcium ions to convert a signal into a response, compared to control.
WB:WBPerson557
Animals exhibit variations in the characteristic movement towards typically attractive alkaline pH (pH higher than 7) compared to control. However animals tend to avoid very high pH levels (pH11). pH is a measure of the acidity or basicity of an aqueous solution. In C. elegans animals chemotax toward higher alkaline pH.
C_elegans_phenotype_ontology
alkaline pH sensing variant
alkalinity sensing variant
WBPhenotype:0002171
alkaline pH chemotaxis variant
Animals exhibit variations in the characteristic movement towards typically attractive alkaline pH (pH higher than 7) compared to control. However animals tend to avoid very high pH levels (pH11). pH is a measure of the acidity or basicity of an aqueous solution. In C. elegans animals chemotax toward higher alkaline pH.
GO:0036176
WB:WBPaper00042397
WB:WBPerson557
Infected animals exhibit variations in the process of releasing pathogens back into the environment, compared to control.
spore shedding variant
C_elegans_phenotype_ontology
WBPhenotype:0002172
pathogen release variant
Infected animals exhibit variations in the process of releasing pathogens back into the environment, compared to control.
WB:WBPaper00040246
WB:WBPerson2987
Animals exhibit variations in the number of cells that make up the organism compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002173
cell number variant
Animals exhibit variations in the number of cells that make up the organism compared to control animals.
WB:WBPaper00032029
WB:WBPerson2987
The number of cells in the organism is reduced compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002174
cell number decreased
The number of cells in the organism is reduced compared to control animals.
WB:WBPaper00032029
WB:WBPerson2987
The number of cells in the organism is increased compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002175
cell number increased
The number of cells in the organism is increased compared to control animals.
WB:WBPaper00032029
WB:WBPerson2987
Animals exhibit variations in the structure, organization or placement of the population of the lateral, alae-producing epithelial cells (seam cells), compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002176
seam cell morphology variant
Animals exhibit variations in the structure, organization or placement of the population of the lateral, alae-producing epithelial cells (seam cells), compared to that observed in control animals.
WB:WBPaper00032029
WB:WBPerson2987
Any variation in the components that make up the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002177
plasma membrane composition variant
Any variation in the components that make up the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control.
GO:0005886
WB:WBPerson2987
WB:WBPerson557
Any variation in the components that make up either of the two leaflets of the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002178
plasma membrane leaflet composition variant
Any variation in the components that make up either of the two leaflets of the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control.
GO:0009897
GO:0009898
WB:WBPerson2987
WB:WBPerson557
Animals do not arrest mitotic germ cell division, as control animals, when treated with X-ray radiation.
C_elegans_phenotype_ontology
WBPhenotype:0002179
X ray induced mitotic germ cell arrest defective
Animals do not arrest mitotic germ cell division, as control animals, when treated with X-ray radiation.
WB:WBPaper00004952
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the process by which cells having undergone programmed cell death are shed or extruded into the extracellular environment.
C_elegans_phenotype_ontology
WBPhenotype:0002180
apoptotic cell shedding variant
Animals exhibit variations in the process by which cells having undergone programmed cell death are shed or extruded into the extracellular environment.
WB:WBPaper00041303
WB:WBPerson2987
Animals produce an excess number of excretory cells compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002181
extra excretory cells
Animals produce an excess number of excretory cells compared to controls.
WB:WBPaper00041303
WB:WBPerson2987
Animals exhibit variations in endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002182
reactive oxygen species homeostasis variant
Animals exhibit variations in endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals.
WB:WBPaper00042351
WB:WBPerson2987
Animals exhibit variations in levels of DNA damage caused by oxidative stress.
C_elegans_phenotype_ontology
WBPhenotype:0002183
oxidative DNA damage variant
Animals exhibit variations in levels of DNA damage caused by oxidative stress.
WB:WBPaper00042351
WB:WBPerson2987
Any variation in the amount of cells undergoing apoptosis in organism as a result of deprivation of nourishment, compared to control. In C. elegans, starvation normally causes increased apoptosis.
C_elegans_phenotype_ontology
WBPhenotype:0002184
starvation induced apoptosis variant
Any variation in the amount of cells undergoing apoptosis in organism as a result of deprivation of nourishment, compared to control. In C. elegans, starvation normally causes increased apoptosis.
WB:WBPaper00044006
WB:WBPerson557
Animals develop endodermal cells/tissue from precursor cells that do not normally produce endodermal cells/tissue.
C_elegans_phenotype_ontology
WBPhenotype:0002185
cell fate transformation to endoderm
Animals develop endodermal cells/tissue from precursor cells that do not normally produce endodermal cells/tissue.
WB:WBPaper00003645
WB:WBPerson2987
Animals develop pharyngeal muscles from precursor cells that do not normally produce pharyngeal muscles.
C_elegans_phenotype_ontology
WBPhenotype:0002186
cell fate transformation to pharyngeal muscle
Animals develop pharyngeal muscles from precursor cells that do not normally produce pharyngeal muscles.
WB:WBPaper00003645
WB:WBPerson2987
Animals develop body wall muscle from precursor cells that do not normally produce body wall muscle.
C_elegans_phenotype_ontology
WBPhenotype:0002187
cell fate transformation to body wall muscle
Animals develop body wall muscle from precursor cells that do not normally produce body wall muscle.
WB:WBPaper00003574
WB:WBPaper00003645
WB:WBPerson2987
Any variation in the progression of the components of the male gonad that are separate from the germline proper over time, from its formation to its mature structure compared to control. In C. elegans, the male somatic gonad consists of three tissues: distal tip cells (DTCs), the seminal vesicle, and the vas deferens (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0002188
male somatic gonad development variant
Any variation in the progression of the components of the male gonad that are separate from the germline proper over time, from its formation to its mature structure compared to control. In C. elegans, the male somatic gonad consists of three tissues: distal tip cells (DTCs), the seminal vesicle, and the vas deferens (Wormatlas).
WB:WBPerson2987
WB:WBPerson557
Animals produce an excess number of linker cells compared to controls.
excess linker cells
C_elegans_phenotype_ontology
WBPhenotype:0002189
extra linker cells
Animals produce an excess number of linker cells compared to controls.
WB:WBPaper00005116
WB:WBPerson2987
The population of hypodermal cells is reduced compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002190
fewer hypodermal cells
The population of hypodermal cells is reduced compared to control animals.
WB:WBPerson557
Animals produce a reduced number of sex myoblasts compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002191
fewer sex myoblasts
Animals produce a reduced number of sex myoblasts compared to controls.
WB:WBPaper00033137
WB:WBPerson2987
Animals produce an excess number of sex myoblasts compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002192
extra sex myoblasts
Animals produce an excess number of sex myoblasts compared to controls.
WB:WBPaper00033137
WB:WBPerson2987
The orientation of the progeny of P7.p mimic those of P5.p and face towards the posterior of the worm, a phenotype referred to as posterior-reversed vulval lineage (P-Rvl).
P-Rvl
C_elegans_phenotype_ontology
WBPhenotype:0002193
posterior reversed vulval lineage
The orientation of the progeny of P7.p mimic those of P5.p and face towards the posterior of the worm, a phenotype referred to as posterior-reversed vulval lineage (P-Rvl).
WB:WBPaper00044058
WB:WBPerson557
Animals do not differ in size when grown on different food sources to the same extent as that measured for control animals. For example, in C. elegans, wild type worms are 1.65 times larger when grown on HB101 compared to those grown on OP50.
C_elegans_phenotype_ontology
WBPhenotype:0002194
food dependent body size variant
Animals do not differ in size when grown on different food sources to the same extent as that measured for control animals. For example, in C. elegans, wild type worms are 1.65 times larger when grown on HB101 compared to those grown on OP50.
WB:WBPaper00038311
WB:WBPerson712
Animals exhibit variations in growth rate or the outcome of growth in response to food compared to control. In C. elegans, animals exhibit an increase or decrease in growth rate depending on the type of bacteria they are fed.
C_elegans_phenotype_ontology
WBPhenotype:0002195
food dependent growth variant
Animals exhibit variations in growth rate or the outcome of growth in response to food compared to control. In C. elegans, animals exhibit an increase or decrease in growth rate depending on the type of bacteria they are fed.
WB:WBPaper00038311
WB:WBPerson712
The driving force of the outward flow of ions does not exceed the inward flow for the opposite driving force or is otherwise altered when compared to that measured for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002196
outward rectifying current variant
The driving force of the outward flow of ions does not exceed the inward flow for the opposite driving force or is otherwise altered when compared to that measured for control animals.
WB:WBPaper00036046
WB:WBPerson712
Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded is altered from that observed for controls.
C_elegans_phenotype_ontology
WBPhenotype:0002197
voltage gated channel activity variant
Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded is altered from that observed for controls.
WB:WBPerson712
The proper localization and assembly of components at the junction of a neuron with a muscle cell varies from that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002198
neuromuscular junction organization variant
The proper localization and assembly of components at the junction of a neuron with a muscle cell varies from that observed in control animals.
WB:WBPaper00038066
WB:WBPerson712
The degree of stimulus-evoked calcium concentration changes differs from that of controls.
C_elegans_phenotype_ontology
WBPhenotype:0002199
neuron calcium transient levels variant
The degree of stimulus-evoked calcium concentration changes differs from that of controls.
WB:WBPaper00039855
WB:WBPerson712
Variations in the progression of the muscles of the adult hermaphrodite oviduct over time from their initial formation to their mature structure compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002200
oviduct muscle defective
Variations in the progression of the muscles of the adult hermaphrodite oviduct over time from their initial formation to their mature structure compared to control.
WB:WBPerson712
Dying animals cells exhibit defects in the fragmentation of chromosomal DNA into oligonucleosomal-length fragments compared to control animals. This process can be monitored by the quantity and quality of TUNEL (TdT-mediated dUTP nick end labeling)-positive nuclei.
C_elegans_phenotype_ontology
WBPhenotype:0002201
apoptotic DNA degradation defective
Dying animals cells exhibit defects in the fragmentation of chromosomal DNA into oligonucleosomal-length fragments compared to control animals. This process can be monitored by the quantity and quality of TUNEL (TdT-mediated dUTP nick end labeling)-positive nuclei.
WB:WBPaper00005978
WB:WBPerson712
Embryos exhibit defects in the extension of pharyngeal cells toward the buccal opening during embryogenesis compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002202
pharynx extension defective
Embryos exhibit defects in the extension of pharyngeal cells toward the buccal opening during embryogenesis compared to controls.
WB:WBPaper00005085
WB:WBPerson712
Corpses resulting from programmed cell death appear different in size or shape from those of corpses in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002203
corpse morphology variant
Corpses resulting from programmed cell death appear different in size or shape from those of corpses in control animals.
WB:WBPaper00004688
WB:WBPerson712
Animals exhibit defects in the muscle contractions of the anterior region of corpus, the area responsible for allowing food to enter the corpus.
C_elegans_phenotype_ontology
WBPhenotype:0002204
procorpus contraction defective
Animals exhibit defects in the muscle contractions of the anterior region of corpus, the area responsible for allowing food to enter the corpus.
WB:WBPaper00005996
WB:WBPerson712
Animals exhibit negative effects on growth, development, or metabolism when exposed to a galactose-rich diet, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002205
hypersensitive to galactose
Animals exhibit negative effects on growth, development, or metabolism when exposed to a galactose-rich diet, compared to control animals.
WB:WBPaper00045849
WB:WBPerson712
Animals process dietary galactose differently than control animals, these differences can result in increased and or decreased levels of intermediary galactose metabolites.
C_elegans_phenotype_ontology
WBPhenotype:0002206
galactose metabolism variant
Animals process dietary galactose differently than control animals, these differences can result in increased and or decreased levels of intermediary galactose metabolites.
WB:WBPaper00045849
WB:WBPerson712
Animals are missing one or both gonad arms, the normally U-shaped projections of the gonad that extend into the anterior or posterior of the animal and bends back towards the center of the animal.
C_elegans_phenotype_ontology
WBPhenotype:0002207
missing gonad arms
Animals are missing one or both gonad arms, the normally U-shaped projections of the gonad that extend into the anterior or posterior of the animal and bends back towards the center of the animal.
WB:WBPaper00003453
WB:WBPerson2987
The expression of a protein, as determined by antibody staining, varied from controls with respect to timing such that the protein was observed to be expressed at earlier timepoints or later timepoints than controls.
C_elegans_phenotype_ontology
WBPhenotype:0002208
antibody temporal expression variant
The expression of a protein, as determined by antibody staining, varied from controls with respect to timing such that the protein was observed to be expressed at earlier timepoints or later timepoints than controls.
WB:WBPaper00003383
WB:WBPerson2987
Any variation in the development of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating.
C_elegans_phenotype_ontology
WBPhenotype:0002209
hook development variant
Any variation in the development of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating.
WB:WBPaper00003428
WB:WBPerson2987
Animals exhibit an extra number of the finger-like sensory sensilla that project from the tail and embed in the male fan.
C_elegans_phenotype_ontology
WBPhenotype:0002210
extra rays
Animals exhibit an extra number of the finger-like sensory sensilla that project from the tail and embed in the male fan.
WB:WBPaper00003428
WB:WBPerson2987
Animals exhibit defects in dye-filling of the neuronal cells of the phasmid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO.
C_elegans_phenotype_ontology
WBPhenotype:0002211
phasmid neuron dye filling defect
Animals exhibit defects in dye-filling of the neuronal cells of the phasmid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO.
WB:WBPaper00003450
WB:WBPerson2987
WB:WBPerson557
Animals exhibit defects in dye-filling of the neuronal cells of the amphid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO.
C_elegans_phenotype_ontology
WBPhenotype:0002212
amphid neuron dye filling defect
Animals exhibit defects in dye-filling of the neuronal cells of the amphid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO.
WB:WBPerson557
Any variation that results in a decrease in the catalytic phosphorylation activity of a kinase enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component). Kinases are enzymes capable of phosphorylating their respective substrates.
C_elegans_phenotype_ontology
WBPhenotype:0002213
kinase activity reduced
Any variation that results in a decrease in the catalytic phosphorylation activity of a kinase enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component). Kinases are enzymes capable of phosphorylating their respective substrates.
WB:WBPaper00003656
WB:WBPerson2987
Animals contain an excess number of pharyngeal muscle cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate.
C_elegans_phenotype_ontology
WBPhenotype:0002214
extra pharyngeal muscle cells
Animals contain an excess number of pharyngeal muscle cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate.
WB:WBPaper00003574
WB:WBPerson2987
Any variation that results in a fewer than control number of body wall muscle cells.
C_elegans_phenotype_ontology
WBPhenotype:0002215
fewer body wall muscles
Any variation that results in a fewer than control number of body wall muscle cells.
WB:WBPaper00003574
WB:WBPerson2987
Any variation in the cellular or subcellular distribution of a gene product, as detected by antibody staining, compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002216
pattern antibody staining variant
Any variation in the cellular or subcellular distribution of a gene product, as detected by antibody staining, compared to that observed in control animals.
WB:WBPaper00003574
WB:WBPaper00003656
WB:WBPerson2987
Animals respond to antimony at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002217
antimony hypersensitive
Animals respond to antimony at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00002619
WB:WBPerson2987
Animals respond to arsenite at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002218
arsenite hypersensitive
Animals respond to arsenite at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00002619
WB:WBPaper00029261
WB:WBPaper00031023
WB:WBPerson2987
Animals respond to fluoranthene at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002219
fluoranthene hypersensitive
Animals respond to fluoranthene at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00031850
WB:WBPerson2987
Animals respond to antimonite at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002220
antimonite hypersensitivity
Animals respond to antimonite at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00029261
WB:WBPerson2987
The pharynx contains cavities, possibly indicative of inappropriate cell death.
C_elegans_phenotype_ontology
WBPhenotype:0002221
pharyngeal vacuole
The pharynx contains cavities, possibly indicative of inappropriate cell death.
WB:WBPaper00004381
WB:WBPerson2987
The uterus contains cavities, possibly indicative of inappropriate cell death.
C_elegans_phenotype_ontology
WBPhenotype:0002222
uterus vacuole
The uterus contains cavities, possibly indicative of inappropriate cell death.
WB:WBPaper00004381
WB:WBPerson2987
Animals respond at a faster rate or to lower concentrations of manganese that that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002223
manganese hypersensitivity
Animals respond at a faster rate or to lower concentrations of manganese that that observed for control animals.
WB:WBPaper00044740
WB:WBPerson712
Animals respond to mercury at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002224
mercury hypersensitive
Animals respond to mercury at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00004381
WB:WBPerson2987
Animals respond to lead at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002225
lead hypersensitive
Animals respond to lead at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00004381
WB:WBPerson2987
Animals respond to cobalt at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002226
cobalt hypersensitive
Animals respond to cobalt at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00005255
WB:WBPaper00006388
WB:WBPerson2987
Animals exhibit variations in their response to lead compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002227
lead response variant
Animals exhibit variations in their response to lead compared to that observed in control animals.
WB:WBPaper00029261
WB:WBPerson2987
Animals exhibit variations in their response to aluminum compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002228
aluminum response variant
Animals exhibit variations in their response to aluminum compared to that observed in control animals.
WB:WBPaper00029261
WB:WBPerson2987
Animals exhibit variations in their response to chromium compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002229
chromium response variant
Animals exhibit variations in their response to chromium compared to that observed in control animals.
WB:WBPaper00029261
WB:WBPerson2987
Animals exhibited higher amounts of internal metal concentrations compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002230
metal accumulation increased
Animals exhibited higher amounts of internal metal concentrations compared to control animals.
WB:WBPaper00044740
WB:WBPerson712
Oxidative stress induced by manganese differs from that of control worms.
C_elegans_phenotype_ontology
WBPhenotype:0002231
manganese induced oxidative stress response
Oxidative stress induced by manganese differs from that of control worms.
WB:WBPaper00044740
WB:WBPerson712
The polarity reversal process by which synaptic components are removed from one side of the synapse and then reformed on the opposite cell does not occur or occurs in a different manner than in controls. In C. elegans, at the end of the L1 stage, the DD neurons undergo a complete polarity reversal such that the ventral synapses disappear and new synapses are formed on opposing dorsal body muscles.
C_elegans_phenotype_ontology
WBPhenotype:0002232
synaptic remodeling variant
The polarity reversal process by which synaptic components are removed from one side of the synapse and then reformed on the opposite cell does not occur or occurs in a different manner than in controls. In C. elegans, at the end of the L1 stage, the DD neurons undergo a complete polarity reversal such that the ventral synapses disappear and new synapses are formed on opposing dorsal body muscles.
WB:WBPaper00005543
WB:WBPerson712
The swimming behavior of animals are influenced or modulate by the osmolarity of the swimming buffer. The swimming of wild-type C. elegans animals are not affected by the osmolarity of the swimming liquid.
C_elegans_phenotype_ontology
WBPhenotype:0002233
osmolarity modulated swimming variant
The swimming behavior of animals are influenced or modulate by the osmolarity of the swimming buffer. The swimming of wild-type C. elegans animals are not affected by the osmolarity of the swimming liquid.
WB:WBPaper00041219
WB:WBPerson712
Animals contain excess acidified intracellular compartments. These compartments are positive for indicators such as Acridine Orange as well as LysoTracker Red, in a lysosome-like manner.
C_elegans_phenotype_ontology
WBPhenotype:0002234
increased acidified compartments
Animals contain excess acidified intracellular compartments. These compartments are positive for indicators such as Acridine Orange as well as LysoTracker Red, in a lysosome-like manner.
WB:WBPaper00005190
WB:WBPerson712
Animals are unable to grow on media depleted of phosphate.
C_elegans_phenotype_ontology
WBPhenotype:0002235
growth defective on low phosphate media
Animals are unable to grow on media depleted of phosphate.
WB:WBPerson712
The degradation of endocytosed and intracellular material does not occur to the same extent as it does in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002236
endo lysosomal degradation pathway defective
The degradation of endocytosed and intracellular material does not occur to the same extent as it does in control animals.
WB:WBPaper00037899
WB:WBPerson712
Animals exhibit disruptions in tubular or tubulo-vesicular structures that function in endocytic transport from early to recycling endosomes.
ERC organization and biogenesis defective
C_elegans_phenotype_ontology
WBPhenotype:0002237
endocytic recycling compartment organization and biogenesis defective
Animals exhibit disruptions in tubular or tubulo-vesicular structures that function in endocytic transport from early to recycling endosomes.
WB:WBPaper00037899
WB:WBPerson712
Animals exhibit increased endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002238
increased levels of reactive oxygen species
Animals exhibit increased endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals.
WB:WBPaper00040454
WB:WBPerson2987
Animals exhibit reduced endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002239
reduced levels of reactive oxygen species
Animals exhibit reduced endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals.
WB:WBPaper00040454
WB:WBPerson2987
Any variation in the morphology of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
C_elegans_phenotype_ontology
WBPhenotype:0002240
gut granule morphology variant
Any variation in the morphology of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas).
WB:WBPaper00040622
WB:WBPerson2987
Animals consume less food than control animals
C_elegans_phenotype_ontology
WBPhenotype:0002241
feeding reduced
Animals consume less food than control animals
WB:WBPaper00036303
WB:WBPerson2987
Animals exhibit detrimental responses to iron deficiency more readily than control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002242
hypersensitive to iron deficiency
Animals exhibit detrimental responses to iron deficiency more readily than control animals.
WB:WBPaper00040550
WB:WBPerson2987
Animals do not produce the same amount of functional phytochelatins as measured in control worms. Phytochelatins are any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
C_elegans_phenotype_ontology
WBPhenotype:0002243
phytochelatin synthesis deficient
Animals do not produce the same amount of functional phytochelatins as measured in control worms. Phytochelatins are any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
GO:0046938
WB:WBPaper00036020
WB:WBPerson712
Animals respond to arsenic at a lower concentration or at a shorter exposure time compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002244
arsenic hypersensitive
Animals respond to arsenic at a lower concentration or at a shorter exposure time compared to control animals.
WB:WBPaper00036020
WB:WBPerson712
Animals exhibit reduced levels of endogenous zinc compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002245
endogenous zinc levels reduced
Animals exhibit reduced levels of endogenous zinc compared to control animals.
WB:WBPaper00040622
WB:WBPerson2987
Animals exhibit increased levels of endogenous zinc compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002246
endogenous zinc levels increased
Animals exhibit increased levels of endogenous zinc compared to control animals.
WB:WBPaper00040622
WB:WBPerson2987
Variations in the regulation of levels, transport, and metabolism of copper ions within an organism compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002247
copper homeostasis variant
Variations in the regulation of levels, transport, and metabolism of copper ions within an organism compared to control.
WB:WBPaper00040622
WB:WBPerson2987
Animals exhibit detrimental responses to zinc deficiency more readily than control animals
C_elegans_phenotype_ontology
WBPhenotype:0002248
hypersensitive to zinc deficiency
Animals exhibit detrimental responses to zinc deficiency more readily than control animals
WB:WBPaper00040622
WB:WBPerson2987
Protein oxidation levels, as measured by carbonylated protein levels for example, are reduced compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002249
reduced protein oxidation levels
Protein oxidation levels, as measured by carbonylated protein levels for example, are reduced compared to controls.
WB:WBPaper00040914
WB:WBPerson2987
Animals respond to silver at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002250
silver hypersensitive
Animals respond to silver at a lower concentration or a shorter exposure compared to control animals.
WB:WBPerson557
Animals respond to silver nanoparticles (AgNPs) at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002251
silver nanoparticle hypersensitive
Animals respond to silver nanoparticles (AgNPs) at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00044630
WB:WBPerson2987
Animals are more prone to infection by virus compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002252
increased susceptibility to viral infection
Animals are more prone to infection by virus compared to control animals.
WB:WBPaper00046393
WB:WBPerson712
Animals exhibit lowered levels of any or all of the clades of 22G RNA molecules, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002253
22G RNA expression reduced
Animals exhibit lowered levels of any or all of the clades of 22G RNA molecules, compared to control.
WB:WBPaper00046393
WB:WBPerson712
Three-prime (3') uridylation of mRNA targeted for silencing does not occur at the same rate or extent of targeted mRNA in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002254
three prime target RNA uridylation reduced
Three-prime (3') uridylation of mRNA targeted for silencing does not occur at the same rate or extent of targeted mRNA in control animals.
WB:WBPaper00046393
WB:WBPerson712
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of amino acids within the organism or cell compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002255
amino acid metabolism variant
Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of amino acids within the organism or cell compared to control.
WB:WBPaper00038278
WB:WBPerson2987
Animals exhibit variations in their response to selenium compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002256
selenium response variant
Animals exhibit variations in their response to selenium compared to that observed in control animals.
WB:WBPaper00038278
WB:WBPerson2987
Animals respond to iron at a lower concentration or a shorter exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002257
iron hypersensitive
Animals respond to iron at a lower concentration or a shorter exposure compared to control animals.
WB:WBPaper00038278
WB:WBPerson2987
Animals fail to exhibit toxicity to the concentration of nickel that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to nickel include delayed development or lethality.
C_elegans_phenotype_ontology
WBPhenotype:0002258
nickel toxicity resistant
Animals fail to exhibit toxicity to the concentration of nickel that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to nickel include delayed development or lethality.
WB:WBPaper00038278
WB:WBPerson2987
The number of terminal regions of a neuron's dendrite is less that that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002259
dendritic termini number reduced
The number of terminal regions of a neuron's dendrite is less that that observed for control animals.
WB:WBPaper00046432
WB:WBPerson557
WB:WBPerson712
Ooctyes and or sperm appear vacuolated and degenerated compared to gametes in control animals. This degeneration is not due to normal programmed cell death.
C_elegans_phenotype_ontology
necrotic gamete degeneration increased
WBPhenotype:0002260
gamete necrotic death increased
Ooctyes and or sperm appear vacuolated and degenerated compared to gametes in control animals. This degeneration is not due to normal programmed cell death.
WB:WBPaper00041364
WB:WBPerson712
An effective connection between reciprocal target neurons is not established properly.
C_elegans_phenotype_ontology
WBPhenotype:0002261
neurite connectivity defective
An effective connection between reciprocal target neurons is not established properly.
WB:WBPaper00042557
WB:WBPerson712
Animals display variations in the distribution of the constituents of the postsynaptic side of the active zone, compared to control animals, that are required for receiving signals from the presynaptic side.
C_elegans_phenotype_ontology
WBPhenotype:0002262
postsynaptic component localization variant
Animals display variations in the distribution of the constituents of the postsynaptic side of the active zone, compared to control animals, that are required for receiving signals from the presynaptic side.
WB:WBPaper00005543
WB:WBPaper00038066
WB:WBPerson712
Any increase in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002263
mitochondrial membrane potential increased
Any increase in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control.
WB:WBPaper00040353
WB:WBPerson557
Animals exhibit an increase in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology.
C_elegans_phenotype_ontology
WBPhenotype:0002264
ATP levels increased
Animals exhibit an increase in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology.
WB:WBPaper00036073
WB:WBPaper00040353
WB:WBPerson557
Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002265
lysosome-related organelle biogenesis variant
Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
WB:WBPaper00041842
WB:WBPerson2987
Animals exhibit variations in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining.
C_elegans_phenotype_ontology
WBPhenotype:0002266
mitochondrial content variant
Animals exhibit variations in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining.
WB:WBPaper00035277
WB:WBPerson2987
Animals exhibit increases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining.
C_elegans_phenotype_ontology
WBPhenotype:0002267
mitochondrial content increased
Animals exhibit increases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining.
WB:WBPaper00035277
WB:WBPerson2987
Animals exhibit decreases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining.
C_elegans_phenotype_ontology
WBPhenotype:0002268
mitochondrial content decreased
Animals exhibit decreases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining.
WB:WBPaper00035277
WB:WBPerson2987
Animals exhibit an increased rate of oxygen utilization compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002269
oxygen consumption increased
Animals exhibit an increased rate of oxygen utilization compared to control animals.
WB:WBPaper00035277
WB:WBPerson2987
Animals exhibit a decrease in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism
C_elegans_phenotype_ontology
WBPhenotype:0002270
metabolite content decreased
Animals exhibit a decrease in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism
WB:WBPaper00040386
WB:WBPerson2987
Animals exhibit variations in the rate at which food is absorbed by the intestine, as determined by a time-course recording of fat staining (by C1-BODIPY-C12, for example) normalized to controls
C_elegans_phenotype_ontology
WBPhenotype:0002271
food absorption rate variant
Animals exhibit variations in the rate at which food is absorbed by the intestine, as determined by a time-course recording of fat staining (by C1-BODIPY-C12, for example) normalized to controls
WB:WBPaper00032310
WB:WBPerson2987
Animals exhibit variations in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone.
C_elegans_phenotype_ontology
WBPhenotype:0002272
protein carbonylation variant
Animals exhibit variations in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone.
WB:WBPaper00006515
Animals exhibit enhanced negative effects on growth, health, development or metabolism, in response to dietary sugar-rich diets, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002273
dietary sugar response variant
Animals exhibit enhanced negative effects on growth, health, development or metabolism, in response to dietary sugar-rich diets, compared to controls.
WB:WBPaper00045849
WB:WBPerson712
Males receive copulatory plugs from other males, deposited elsewhere on their bodies, in the absence of any orifice. This typically involves penetration of the depositing male's spicules directly through the cuticle of the recipient male.
Plob
C_elegans_phenotype_ontology
WBPhenotype:0002274
plugged on body
Males receive copulatory plugs from other males, deposited elsewhere on their bodies, in the absence of any orifice. This typically involves penetration of the depositing male's spicules directly through the cuticle of the recipient male.
WB:WBPerson22615
WB:WBPerson7165
Males receive copulatory plugs from other males, deposited on their excretory pores. This phenotype is polymorphic among C. elegans strains and also in C. briggsae.
Pleb
C_elegans_phenotype_ontology
Plep
WBPhenotype:0002275
plugged excretory pore
Males receive copulatory plugs from other males, deposited on their excretory pores. This phenotype is polymorphic among C. elegans strains and also in C. briggsae.
WB:WBPerson22615
WB:WBPerson7165
The life span of dauer-staged animals is shorter than that observed in control dauer animals.
C_elegans_phenotype_ontology
WBPhenotype:0002276
dauer lifespan shortened
The life span of dauer-staged animals is shorter than that observed in control dauer animals.
WB:WBPaper00032396
WB:WBPerson2987
The life span of dauer-staged animals is longer than that observed in control dauer animals.
C_elegans_phenotype_ontology
WBPhenotype:0002277
dauer lifespan extended
The life span of dauer-staged animals is longer than that observed in control dauer animals.
WB:WBPaper00032396
WB:WBPerson2987
Animals do not develop acute functional tolerance to alcohol after a short exposure, unlike that observed in control animals
C_elegans_phenotype_ontology
ATF
WBPhenotype:0002278
acute functional tolerance to alcohol defective
Animals do not develop acute functional tolerance to alcohol after a short exposure, unlike that observed in control animals
WB:WBPaper00046494
WB:WBPerson712
Animals exhibit a decrease in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining.
C_elegans_phenotype_ontology
lipid body size decreased
WBPhenotype:0002279
fat associated body size decreased
Animals exhibit a decrease in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining.
WB:WBPaper00042257
WB:WBPerson2987
Animals exhibit resistance to osmotic stress compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002280
organism osmotic stress resistant
Animals exhibit resistance to osmotic stress compared to that observed in control animals.
WB:WBPaper00032396
WB:WBPerson2987
Animals exhibit hypersensitivty to osmotic stress compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002281
organism osmotic stress hypersensitive
Animals exhibit hypersensitivty to osmotic stress compared to that observed in control animals.
WB:WBPaper00032396
WB:WBPerson2987
Animals exhibit increased levels of the process by which their cells digest parts of their own cytoplasm, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002282
autophagy increased
Animals exhibit increased levels of the process by which their cells digest parts of their own cytoplasm, compared to control.
WB:WBPaper00026641
WB:WBPaper00038332
WB:WBPaper00041372
WB:WBPaper00043981
WB:WBPerson2987
WB:WBPerson557
Animals exhibit reduced levels of the process by which their cells digest parts of their own cytoplasm, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002283
autophagy reduced
Animals exhibit reduced levels of the process by which their cells digest parts of their own cytoplasm, compared to control.
WB:WBPaper00006070
WB:WBPaper00035076
WB:WBPaper00041851
WB:WBPaper00043981
WB:WBPerson2987
WB:WBPerson557
Any variation in the extent of the maximum flex of the most anterior portion of the animal compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002284
head bend angle variant
Any variation in the extent of the maximum flex of the most anterior portion of the animal compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the extent of the maximum flex of the most anterior portion of the animal compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002285
head bend angle decreased
Animals exhibit a decrease in the extent of the maximum flex of the most anterior portion of the animal compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the extent of the maximum flex of the most anterior portion of the animal compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002286
head bend angle increased
Animals exhibit an increase in the extent of the maximum flex of the most anterior portion of the animal compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
The most posterior portion of the animal exhibits variations in its movement compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002287
tail movement variant
The most posterior portion of the animal exhibits variations in its movement compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Any variation in the extent of the maximum flex of the most posterior portion of the animal compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002288
tail bend angle variant
Any variation in the extent of the maximum flex of the most posterior portion of the animal compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the extent of the maximum flex of the most posterior portion of the animal compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002289
tail bend angle increased
Animals exhibit an increase in the extent of the maximum flex of the most posterior portion of the animal compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the extent of the maximum flex of the most posterior portion of the animal compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002290
tail bend angle decreased
Animals exhibit a decrease in the extent of the maximum flex of the most posterior portion of the animal compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in body posture with regard to the extent of displacement measured from the mean position to an extreme position compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002291
body posture amplitude variant
Animals exhibit variations in body posture with regard to the extent of displacement measured from the mean position to an extreme position compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in body posture caused by a decrease in the extent of displacement measured from the mean position to an extreme position compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002292
body posture amplitude decreased
Animals exhibit variations in body posture caused by a decrease in the extent of displacement measured from the mean position to an extreme position compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in body posture caused by an increase in the extent of displacement measured from the mean position to an extreme position compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002293
body posture amplitude increased
Animals exhibit variations in body posture caused by an increase in the extent of displacement measured from the mean position to an extreme position compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in body posture with regard to the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal.
C_elegans_phenotype_ontology
WBPhenotype:0002294
body posture wavelength variant
Animals exhibit variations in body posture with regard to the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in body posture caused by a decrease in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal.
C_elegans_phenotype_ontology
WBPhenotype:0002295
body posture wavelength decreased
Animals exhibit variations in body posture caused by a decrease in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in body posture caused by an increase in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal.
C_elegans_phenotype_ontology
WBPhenotype:0002296
body posture wavelength increased
Animals exhibit variations in body posture caused by an increase in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the occurrence of a coil-like body posture compared to control animals. This includes the amount of time spent in a coil, the frequency with which coils form and the inappropriate formation of a coil, for example when attempting to locomote.
C_elegans_phenotype_ontology
WBPhenotype:0002297
coiling variant
Animals exhibit variations in the occurrence of a coil-like body posture compared to control animals. This includes the amount of time spent in a coil, the frequency with which coils form and the inappropriate formation of a coil, for example when attempting to locomote.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the amount of time spent with its body posture in a coil or the frequency with which they form coils compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002298
coiling frequency variant
Animals exhibit variations in the amount of time spent with its body posture in a coil or the frequency with which they form coils compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals spend less time with their body posture in a coil or they decrease the frequency with which they form coils compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002299
coiling frequency decreased
Animals spend less time with their body posture in a coil or they decrease the frequency with which they form coils compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals spend more time with their body posture in a coil or they increase the frequency with which they form coils compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002300
coiling frequency increased
Animals spend more time with their body posture in a coil or they increase the frequency with which they form coils compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
The extreme anterior of the animal exhibits variations in its movement compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002301
nose movement variant
The extreme anterior of the animal exhibits variations in its movement compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the movement of the extreme anterior portion of the body to a new location compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002302
nose movement decreased
Animals exhibit a decrease in the movement of the extreme anterior portion of the body to a new location compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the movement of the extreme anterior portion of the body to a new location compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002303
nose movement increased
Animals exhibit an increase in the movement of the extreme anterior portion of the body to a new location compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the movement of the most anterior portion of the body to a new location compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002304
head movement decreased
Animals exhibit a decrease in the movement of the most anterior portion of the body to a new location compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the movement of the most anterior portion of the body to a new location compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002305
head movement increased
Animals exhibit an increase in the movement of the most anterior portion of the body to a new location compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the movement of the most posterior portion of the body to a new location compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002306
tail movement decreased
Animals exhibit a decrease in the movement of the most posterior portion of the body to a new location compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the movement of the most posterior portion of the body to a new location compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002307
tail movement increased
Animals exhibit an increase in the movement of the most posterior portion of the body to a new location compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002308
pausing variant
Animals exhibit variations in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002309
pausing decreased
Animals exhibit a decrease in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002310
pausing increased
Animals exhibit an increase in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Variations in the behavior by which an organism alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
C_elegans_phenotype_ontology
WBPhenotype:0002311
turning variant
Variations in the behavior by which an organism alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
C_elegans_phenotype_ontology
WBPhenotype:0002312
turning frequency variant
Animals exhibit variations in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
C_elegans_phenotype_ontology
WBPhenotype:0002313
turning frequency increased
Animals exhibit an increase in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
C_elegans_phenotype_ontology
WBPhenotype:0002314
turning frequency reduced
Animals exhibit a decrease in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal).
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in their movement at high-speed in the forward direction with brief backward movement compared to control. During roaming, control animals often traverse wide regions.
C_elegans_phenotype_ontology
path range variant
WBPhenotype:0002315
roaming variant
Animals exhibit variations in their movement at high-speed in the forward direction with brief backward movement compared to control. During roaming, control animals often traverse wide regions.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the low-speed/high turning movement that restricts them to a confined region compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002316
dwelling variant
Animals exhibit variations in the low-speed/high turning movement that restricts them to a confined region compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the low-speed/high turning movement that usually restricts them to a confined region compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002317
dwelling increased
Animals exhibit an increase in the low-speed/high turning movement that usually restricts them to a confined region compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the low-speed/high turning movement that usually restricts them to a confined region compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002318
dwelling reduced
Animals exhibit a decrease in the low-speed/high turning movement that usually restricts them to a confined region compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in their high-speed movement in the forward direction with brief backward movement compared to control.
C_elegans_phenotype_ontology
path range increased
WBPhenotype:0002319
roaming increased
Animals exhibit an increase in their high-speed movement in the forward direction with brief backward movement compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Variations in the behavior by which an organism shifts from forward to backward movements.
C_elegans_phenotype_ontology
WBPhenotype:0002320
reversal variant
Variations in the behavior by which an organism shifts from forward to backward movements.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit decreased velocity of forward translocation of any point along the animal's track from that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002321
forward point velocity decreased
Animals exhibit decreased velocity of forward translocation of any point along the animal's track from that observed for control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit increased velocity of forward translocation of any point along the animal's track from that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002322
forward point velocity increased
Animals exhibit increased velocity of forward translocation of any point along the animal's track from that observed for control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the velocity of backward translocation of any point along the animal's track from that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002323
backward point velocity variant
Animals exhibit variations in the velocity of backward translocation of any point along the animal's track from that observed for control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit decreased velocity of backward translocation of any point along the animal's track from that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002324
backward point velocity decreased
Animals exhibit decreased velocity of backward translocation of any point along the animal's track from that observed for control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit increased velocity of backward translocation of any point along the animal's track from that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002325
backward point velocity increased
Animals exhibit increased velocity of backward translocation of any point along the animal's track from that observed for control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the net velocity of an animal.
C_elegans_phenotype_ontology
sluggish
WBPhenotype:0002326
velocity of movement decreased
Animals exhibit a decrease in the net velocity of an animal.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the net velocity of an animal
C_elegans_phenotype_ontology
WBPhenotype:0002327
velocity of movement increased
Animals exhibit an increase in the net velocity of an animal
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control.
amplitude of body bends increased
C_elegans_phenotype_ontology
WBPhenotype:0002328
amplitude of sinusoidal movement increased
Animals exhibit an increase in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0002329
obsolete temporal frequency of sinusoidal movement variant
true
OBSOLETE.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0002330
obsolete temporal frequency of sinusoidal movement decreased
true
OBSOLETE.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0002331
obsolete temporal frequency of sinusoidal movement increased
true
OBSOLETE.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope.
C_elegans_phenotype_ontology
WBPhenotype:0002332
track length variant
Animals exhibit variations in the length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit increased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope.
C_elegans_phenotype_ontology
WBPhenotype:0002333
track length increased
Animals exhibit increased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit decreased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope.
C_elegans_phenotype_ontology
WBPhenotype:0002334
track length decreased
Animals exhibit decreased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the extent to which the overall path of movement is curved, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002335
path curvature variant
Animals exhibit variations in the extent to which the overall path of movement is curved, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit increases in the extent to which the overall path of movement is curved, producing tighter and more frequent curves compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002336
path curvature increased
Animals exhibit increases in the extent to which the overall path of movement is curved, producing tighter and more frequent curves compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit decreases in the extent to which the overall path of movement is curved, producing shallower, less frequent curves and an overall straighter path, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002337
path curvature decreased
Animals exhibit decreases in the extent to which the overall path of movement is curved, producing shallower, less frequent curves and an overall straighter path, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002338
body proportion variant
Animals exhibit variations in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit increases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002339
body proportion increased
Animals exhibit increases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit decreases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002340
body proportion decreased
Animals exhibit decreases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit variations in instantaneous posture with regards to eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends.
C_elegans_phenotype_ontology
WBPhenotype:0002341
bent posture variant
Animals exhibit variations in instantaneous posture with regards to eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit increased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends.
C_elegans_phenotype_ontology
WBPhenotype:0002342
bent posture increased
Animals exhibit increased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit decreased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends.
C_elegans_phenotype_ontology
WBPhenotype:0002343
bent posture decreased
Animals exhibit decreased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals spend less time backing compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002344
backing decreased
Animals spend less time backing compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Variations in the spontaneous or induced forward crawling locomotion of an animal compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002345
forward locomotion variant
Variations in the spontaneous or induced forward crawling locomotion of an animal compared to control.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals spend more time in forward locomotion, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002346
forward locomotion increased
Animals spend more time in forward locomotion, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals spend less time in forward locomotion, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002347
forward locomotion decreased
Animals spend less time in forward locomotion, compared to control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the frequency of oscillations between adjacent body segments from that observed for control animals.
WBPhenotype:0002331
frequency of sinusoidal movement increased
temporal frequency of sinusoidal movement increased
C_elegans_phenotype_ontology
WBPhenotype:0002348
frequency of body bends increased
Animals exhibit an increase in the frequency of oscillations between adjacent body segments from that observed for control animals.
WB:WBPaper00043908
WB:WBPerson2987
WB:WBPerson557
The levels of phosphatidylinositol 3-phosphate (a.k.a. PtdIns3P or PI3P) are reduced compared to those of control animals
C_elegans_phenotype_ontology
WBPhenotype:0002349
phosphatidylinositol 3-phosphate levels reduced
The levels of phosphatidylinositol 3-phosphate (a.k.a. PtdIns3P or PI3P) are reduced compared to those of control animals
WB:WBPaper00044390
WB:WBPerson2987
Animals exhibit increases in steady-state levels of hydrogen peroxide (H2O2) compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002350
hydrogen peroxide levels increased
Animals exhibit increases in steady-state levels of hydrogen peroxide (H2O2) compared to control.
WB:WBPaper00041478
WB:WBPerson2987
Animals exhibit reductions in steady-state levels of hydrogen peroxide (H2O2) compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002351
hydrogen peroxide levels reduced
Animals exhibit reductions in steady-state levels of hydrogen peroxide (H2O2) compared to control.
WB:WBPaper00041478
WB:WBPerson2987
Animals exhibit elevated levels of transfer RNA compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002352
tRNA expression increased
Animals exhibit elevated levels of transfer RNA compared to control.
WB:WBPaper00046188
WB:WBPerson2987
Animals exhibit reduced levels of transfer RNA compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002353
tRNA expression decreased
Animals exhibit reduced levels of transfer RNA compared to control.
WB:WBPaper00046188
WB:WBPerson2987
Animals are more prone to infection from fungal pathogens compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002354
increased susceptibility to fungal infection
Animals are more prone to infection from fungal pathogens compared to control animals.
WB:WBPaper00045575
WB:WBPerson712
Animals are more prone to infection by bacterial pathogens compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002355
increased susceptibility to bacterial pathogens
Animals are more prone to infection by bacterial pathogens compared to control animals.
WB:WBPaper00045575
WB:WBPerson712
Animals are negatively affected by bacteria that is nonpathogenic to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002356
sickened by nonpathogenic bacteria
Animals are negatively affected by bacteria that is nonpathogenic to control animals.
WB:WBPaper00045575
WB:WBPerson712
Animals exhibit an increase in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism.
C_elegans_phenotype_ontology
WBPhenotype:0002357
metabolite content increased
Animals exhibit an increase in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism.
WB:WBPaper00045546
WB:WBPaper00045575
WB:WBPerson712
The conversion of one differentiated cell type into another does not occur as it does in control animals. In C. elegans, the Y cell undergoes a dramatic redifferentiation from being a cell in of the rectum to a PDA neuron. This transdifferentiation requires the cell to withdraw from its established position, migrate, and then become a motor neuron.
C_elegans_phenotype_ontology
WBPhenotype:0002358
transdifferentiation defective
The conversion of one differentiated cell type into another does not occur as it does in control animals. In C. elegans, the Y cell undergoes a dramatic redifferentiation from being a cell in of the rectum to a PDA neuron. This transdifferentiation requires the cell to withdraw from its established position, migrate, and then become a motor neuron.
WB:WBPaper00037659
WB:WBPerson712
Animals exhibit an increase in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone.
C_elegans_phenotype_ontology
WBPhenotype:0002359
protein carbonylation increased
Animals exhibit an increase in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone.
WB:WBPaper00041478
WB:WBPerson2987
Animals respond more severely to cold than control animals subjected to the same cold conditions.
C_elegans_phenotype_ontology
WBPhenotype:0002360
cold hypersensitive
Animals respond more severely to cold than control animals subjected to the same cold conditions.
WB:WBPaper00046830
WB:WBPerson2987
Animals exhibit increased fluidity of cell membranes, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002361
membrane fluidity increased
Animals exhibit increased fluidity of cell membranes, compared to control animals.
WB:WBPaper00046830
WB:WBPerson2987
Variations in the process by which one or more SUMO moieties are added to a protein, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002362
protein sumoylation variant
Variations in the process by which one or more SUMO moieties are added to a protein, compared to control.
WB:WBPaper00048594
WB:WBPerson2987
WB:WBPerson557
Animals are more resistant to the reduction of cholesterol in the environment compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002363
cholesterol depletion resistant
Animals are more resistant to the reduction of cholesterol in the environment compared to control animals.
WB:WBPaper00024451
WB:WBPerson2987
WB:WBPerson557
Spontaneous axon breaks leading to degeneration of separated segments.
axon degeneration
C_elegans_phenotype_ontology
WBPhenotype:0002364
axonal degeneration
Spontaneous axon breaks leading to degeneration of separated segments.
WB:WBPaper00024451
WB:WBPerson2987
WB:WBPerson9270
Following axon damage, animals do not undergo axonal fusion after reconnection between the regrowing axon and its separated segment to the same extent as observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002365
regenerative axonal fusion defective
Following axon damage, animals do not undergo axonal fusion after reconnection between the regrowing axon and its separated segment to the same extent as observed in control animals.
WB:WBPaper00046306
WB:WBPerson29819
WB:WBPerson2987
Animals do not suppress exploratory head movements in response to anterior touch stimuli, unlike control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002366
touch-induced suppression of head movement defective
Animals do not suppress exploratory head movements in response to anterior touch stimuli, unlike control animals.
WB:WBPaper00039982
WB:WBPerson712
Animals are less successful than controls in extracting themselves from mesh or other non-living obstructing obstacles.
C_elegans_phenotype_ontology
WBPhenotype:0002367
non-living barrier escape defective
Animals are less successful than controls in extracting themselves from mesh or other non-living obstructing obstacles.
WB:WBPaper00039982
WB:WBPerson712
Lysosomal refractile bodies are apoptotic-like cell corpse; however, they differ in size and shape and can be described as resembling irregular cell corpses. These bodies have been shown to represent enlarged lysosomes and can occur in conjunction with altered programmed cell death programs.
C_elegans_phenotype_ontology
WBPhenotype:0002368
lysosomal refractile body accumulation
Lysosomal refractile bodies are apoptotic-like cell corpse; however, they differ in size and shape and can be described as resembling irregular cell corpses. These bodies have been shown to represent enlarged lysosomes and can occur in conjunction with altered programmed cell death programs.
WB:WBPaper00005190
WB:WBPerson712
Animals exhibit sister cells that have lost otherwise normal asynchrony of cell division timing, compared to control animals. This results in sister cells aberrantly dividing in synchrony.
C_elegans_phenotype_ontology
WBPhenotype:0002369
sister cell division timing asynchrony reduced
Animals exhibit sister cells that have lost otherwise normal asynchrony of cell division timing, compared to control animals. This results in sister cells aberrantly dividing in synchrony.
WB:WBPaper00046953
WB:WBPerson2987
Animals fail to execute their characteristic movements to avoid noxious heat in a manner consistent with controls.
C_elegans_phenotype_ontology
WBPhenotype:0002370
noxious heat avoidance defective
Animals fail to execute their characteristic movements to avoid noxious heat in a manner consistent with controls.
WB:WBPaper00046106
WB:WBPerson12691
WB:WBPerson557
Vesicles, including those in cells, cell bodies, or synaptic terminals, do not properly form or maintain an intermediate state, such as remain coated with a clathrin coat.
C_elegans_phenotype_ontology
WBPhenotype:0002371
vesicle maturation defective
Vesicles, including those in cells, cell bodies, or synaptic terminals, do not properly form or maintain an intermediate state, such as remain coated with a clathrin coat.
WB:WBPaper00004275
WB:WBPerson712
Vesicles in the presynaptic terminal differ in size, shape, or composition from those observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002372
presynaptic vesicle morphology altered
Vesicles in the presynaptic terminal differ in size, shape, or composition from those observed in control animals.
WB:WBPaper00004275
WB:WBPerson712
Animals show a stronger preference for a particular bacterium that has been grown under conditions that differ from a control lawn.
C_elegans_phenotype_ontology
WBPhenotype:0002373
conditional attraction to bacterial lawn
Animals show a stronger preference for a particular bacterium that has been grown under conditions that differ from a control lawn.
WB:WBPaper00048410
WB:WBPerson712
Animals are deficient in the transport of silencing RNAs between cells during the systemic RNAi response process.
C_elegans_phenotype_ontology
WBPhenotype:0002374
RNAi transport defective
Animals are deficient in the transport of silencing RNAs between cells during the systemic RNAi response process.
WB:WBPaper00041467
WB:WBPerson712
Animals that exhibit paralysis (reduced thrashing) revert back to normal swimming behavior that can be tabulated as a reversion index (number revertants/number paralysis) and reversion probability (time in reversion/time after paralysis).
C_elegans_phenotype_ontology
WBPhenotype:0002375
reversion of swimming paralysis
Animals that exhibit paralysis (reduced thrashing) revert back to normal swimming behavior that can be tabulated as a reversion index (number revertants/number paralysis) and reversion probability (time in reversion/time after paralysis).
WB:WBPaper00041219
WB:WBPerson712
Animals exhibit one or more mRNAs with decreased length of the 3' polyadenine tail, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002376
mRNA poly-A tail length decreased
Animals exhibit one or more mRNAs with decreased length of the 3' polyadenine tail, compared to control.
WB:WBPaper00046960
WB:WBPerson2987
Animals exhibit one or more mRNAs with increased length of the 3' polyadenine tail, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002377
mRNA poly-A tail length increased
Animals exhibit one or more mRNAs with increased length of the 3' polyadenine tail, compared to control.
WB:WBPaper00046960
WB:WBPerson2987
Variations in the characteristic movement away from specific disease causing agents (pathogens) compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002378
pathogen avoidance variant
Variations in the characteristic movement away from specific disease causing agents (pathogens) compared to control animals.
WB:WBPaper00048530
WB:WBPerson495
WB:WBPerson557
The subcellular localization of mitochondrial organelles differ from that observed in control cells.
C_elegans_phenotype_ontology
WBPhenotype:0002379
mitochondria localization variant
The subcellular localization of mitochondrial organelles differ from that observed in control cells.
WB:WBPaper00045008
WB:WBPerson298
WB:WBPerson557
Neurons undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles at a faster rate or greater extent than those under conditions that elicit this response in control animals.
C_elegans_phenotype_ontology
increased neurodegeneration
WBPhenotype:0002380
neuron degeneration enhanced
Neurons undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles at a faster rate or greater extent than those under conditions that elicit this response in control animals.
WB:WBPaper00045008
WB:WBPerson298
WB:WBPerson557
Animals exhibit variations in the amount and/or quality of pheromone produced compared to control animals at a defined stage.
C_elegans_phenotype_ontology
WBPhenotype:0002381
pheromone production variant
Animals exhibit variations in the amount and/or quality of pheromone produced compared to control animals at a defined stage.
WB:WBPaper00046134
WB:WBPerson14245
WB:WBPerson557
Animals fail to respond to the concentration of a bioactive compound that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. A bioactive compound is a chemical found in small amounts in organisms or, synthetically produced, that has effects on biological processes in another organism.
C_elegans_phenotype_ontology
WBPhenotype:0002382
resistant to bioactive compound
Animals fail to respond to the concentration of a bioactive compound that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. A bioactive compound is a chemical found in small amounts in organisms or, synthetically produced, that has effects on biological processes in another organism.
WB:WBPaper00045930
WB:WBPerson12526
WB:WBPerson557
Any variation in the decreased behavioral response to repeated light head or tail touch compared to control. A gentle touch to the animal's head causes backward movement, whereas a gentle touch to the animal's tail causes forward movement. When wild-type animals are touched repeatedly on the head or tail, after some repetition they stop responding to the touch stimulus.
C_elegans_phenotype_ontology
WBPhenotype:0002383
light touch habituation variant
Any variation in the decreased behavioral response to repeated light head or tail touch compared to control. A gentle touch to the animal's head causes backward movement, whereas a gentle touch to the animal's tail causes forward movement. When wild-type animals are touched repeatedly on the head or tail, after some repetition they stop responding to the touch stimulus.
WB:WBPaper00041335
WB:WBPerson5092
WB:WBPerson557
Animals are resistant to the toxicity of an anti-infective xenobiotic such as R24. Such small molecules protect the host from bacterial infection by inducing antibacterial immune responses via the p38 MAPK pathway. These molecules tend to have toxic effects in addition to immunostimulatory activity.
Xts
C_elegans_phenotype_ontology
Xenobiotic toxicity resistant
WBPhenotype:0002384
xenotoxicity suppressor
Animals are resistant to the toxicity of an anti-infective xenobiotic such as R24. Such small molecules protect the host from bacterial infection by inducing antibacterial immune responses via the p38 MAPK pathway. These molecules tend to have toxic effects in addition to immunostimulatory activity.
WB:WBPerson512
Animals fail to avoid a high pH (alkaline) environment as compared to control animals. This is at very high pH, for example around pH11.
C_elegans_phenotype_ontology
WBPhenotype:0002385
high pH avoidance defective
Animals fail to avoid a high pH (alkaline) environment as compared to control animals. This is at very high pH, for example around pH11.
WB:WBPaper00043891
WB:WBPerson1928
Animals exhibit variations in the assembly of the fibrous body-membranous organelle (FB-MO), a nematode sperm-specific organelle involved in cytoplasmic partitioning during spermatogenesis, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002386
fibrous body-membranous organelle (FB-MO) assembly variant
Animals exhibit variations in the assembly of the fibrous body-membranous organelle (FB-MO), a nematode sperm-specific organelle involved in cytoplasmic partitioning during spermatogenesis, compared to control animals.
WB:WBPaper00041071
WB:WBPerson602
Dividing cells exhibit additional arrays of microtubules emanating from a spindle pole that do not connect to kinetochores, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002387
supernumerary asters
Dividing cells exhibit additional arrays of microtubules emanating from a spindle pole that do not connect to kinetochores, compared to control.
WB:WBPaper00041071
WB:WBPerson602
Any variation in the second stage of cell division, between prophase and anaphase, during which the chromosomes become attached to the spindle fibers.
C_elegans_phenotype_ontology
WBPhenotype:0002388
metaphase variant
Any variation in the second stage of cell division, between prophase and anaphase, during which the chromosomes become attached to the spindle fibers.
WB:WBPaper00000008
WB:WBPerson2987
Any variation in the stage of meiotic or mitotic cell division in which the chromosomes move away from one another to opposite poles of the spindle.
C_elegans_phenotype_ontology
WBPhenotype:0002389
anaphase variant
Any variation in the stage of meiotic or mitotic cell division in which the chromosomes move away from one another to opposite poles of the spindle.
WB:WBPaper00000008
WB:WBPerson2987
Animals exhibit larger variations in cell division timing events than in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002390
variable cell division timing
Animals exhibit larger variations in cell division timing events than in controls.
WB:WBPaper00046953
WB:WBPerson2987
Cells attempt to divide but fail to form two daughter cells.
C_elegans_phenotype_ontology
WBPhenotype:0002391
cytokinesis failure
Cells attempt to divide but fail to form two daughter cells.
WB:WBPaper00041071
WB:WBPerson557
A depletion of somatic, but not germline, lipid stores are observed near the end of the reproductive period.
Asdf
C_elegans_phenotype_ontology
WBPhenotype:0002392
age dependent somatic depletion of fat
A depletion of somatic, but not germline, lipid stores are observed near the end of the reproductive period.
WB:WBPaper00048925
WB:WBPerson2173
Any variation in the processes that govern the directed extension of neurite projections along the anteroposterior axis of the animal compared to controls.
C_elegans_phenotype_ontology
anteroposterior neurite growth variant
WBPhenotype:0002393
anterior posterior neurite growth variant
Any variation in the processes that govern the directed extension of neurite projections along the anteroposterior axis of the animal compared to controls.
WB:WBPaper00041941
WB:WBPerson1687
WB:WBPerson557
The closure of a phagosome does not occur and it remains connected with the plasma membrane, leaving the lumen open to the outside. Complete closure usually occurs once an apoptotic cell has been surrounded by an engulfing cell.
C_elegans_phenotype_ontology
WBPhenotype:0002394
phagosome sealing defective
The closure of a phagosome does not occur and it remains connected with the plasma membrane, leaving the lumen open to the outside. Complete closure usually occurs once an apoptotic cell has been surrounded by an engulfing cell.
WB:WBPaper00048406
WB:WBPerson17560
WB:WBPerson2987
Animals exhibit variations in recognition of cell corpses and initiation of corpse engulfment, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002395
corpse engulfment initiation variant
Animals exhibit variations in recognition of cell corpses and initiation of corpse engulfment, compared to controls.
WB:WBPaper00048406
WB:WBPerson2987
Animals with a tumorous germline exhibit a decreased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002396
tumor prolapse frequency decreased
Animals with a tumorous germline exhibit a decreased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control.
WB:WBPaper00049105
WB:WBPerson2987
Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002397
tumor prolapse frequency increased
Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control.
WB:WBPaper00049105
WB:WBPerson2987
Animals exhibit variations in the aggregation behavior of starved L1 larvae, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002398
starved L1 larvae aggregation variant
Animals exhibit variations in the aggregation behavior of starved L1 larvae, compared to controls.
WB:WBPaper00046860
WB:WBPerson14935
Animals exhibit variations in their response to a specific neurotransmitter compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002399
neurotransmitter response variant
Animals exhibit variations in their response to a specific neurotransmitter compared to that observed in control animals.
WB:WBPaper00048522
WB:WBPerson2987
Animals do not live or live poorly in the presence of glucose concentrations that normally do not have an effect on control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002400
glucose intolerant
Animals do not live or live poorly in the presence of glucose concentrations that normally do not have an effect on control animals.
WB:WBPaper00049467
WB:WBPerson712
The concentration of fatty acids in the animal are greater than that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002401
excess fatty acids
The concentration of fatty acids in the animal are greater than that observed for control animals.
WB:WBPaper00049467
WB:WBPerson712
A cell (or group of cells) is not found in the correct body position compared the placement in control animals.
cell position abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002402
cell position defective
A cell (or group of cells) is not found in the correct body position compared the placement in control animals.
WB:WBPerson557
Ventral midline blastomeres (P cells) are misaligned (not properly paired) along the ventral midline of larval animals.
C_elegans_phenotype_ontology
WBPhenotype:0002403
P cell misalignment at ventral midline
Ventral midline blastomeres (P cells) are misaligned (not properly paired) along the ventral midline of larval animals.
WB:WBPaper00040551
WB:WBPerson2987
Cell-cell contacts are abnormal, compared to control animals.
C_elegans_phenotype_ontology
cell cell contacts abnormal
WBPhenotype:0002404
cell cell contacts abnormal
Cell-cell contacts are abnormal, compared to control animals.
WB:WBPaper00040551
WB:WBPerson2987
Animals exhibit variations in the behavioral response to pheromones, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002405
pheromone behavioral response variant
Animals exhibit variations in the behavioral response to pheromones, compared to control.
WB:WBPaper00040651
WB:WBPerson2987
Any neurite that is extended towards the posterior of the animal from neurons that in wild-type animals make only anterior projections (e.g. D-type neurons in C. elegans).
C_elegans_phenotype_ontology
WBPhenotype:0002406
aberrant posteriorly-directed neurite
Any neurite that is extended towards the posterior of the animal from neurons that in wild-type animals make only anterior projections (e.g. D-type neurons in C. elegans).
WB:WBPerson1687
WB:WBPerson557
Any variation in the overall size of fertilized oocytes that are laid compared to those laid by control animals.
C_elegans_phenotype_ontology
egg size abnormal
WBPhenotype:0002407
egg size variant
Any variation in the overall size of fertilized oocytes that are laid compared to those laid by control animals.
WB:WBPerson557
Any variation that disrupts the cytoplasmic division of a cell during development compared to control.
C_elegans_phenotype_ontology
cytokinesis abnormal
WBPhenotype:0002408
cytokinesis variant
Any variation that disrupts the cytoplasmic division of a cell during development compared to control.
GO:0000910
WB:WBPerson557
One or more extra cleavage furrows are observed in a cell about to undergo division.
C_elegans_phenotype_ontology
WBPhenotype:0002409
extra cleavage furrow
One or more extra cleavage furrows are observed in a cell about to undergo division.
WB:WBPerson557
Cells exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
C_elegans_phenotype_ontology
WBPhenotype:0002410
cleavage furrow defective
Cells exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
GO:0032154
WB:WBPerson557
Cells exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
C_elegans_phenotype_ontology
WBPhenotype:0002411
cleavage furrow initiation defective
Cells exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis.
WB:WBPerson557
Cells exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
C_elegans_phenotype_ontology
WBPhenotype:0002412
cleavage furrow termination defective
Cells exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis.
WB:WBPerson557
Animals have more than one nucleus in a particular cell type.
C_elegans_phenotype_ontology
WBPhenotype:0002413
multiple nuclei
Animals have more than one nucleus in a particular cell type.
WB:WBPerson557
Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart compared to control.
C_elegans_phenotype_ontology
spindle abnormal
WBPhenotype:0002414
spindle variant
Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart compared to control.
GO:0005819
WB:WBPerson557
Cells exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
C_elegans_phenotype_ontology
WBPhenotype:0002415
spindle assembly defective
Cells exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
GO:0051225
WB:WBPerson557
Any variation in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002416
spindle position variant
Any variation in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis compared to control.
GO:0051653
WB:WBPerson557
Any variation in the rotation of the spindle compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002417
spindle rotation variant
Any variation in the rotation of the spindle compared to control.
WB:WBPerson557
Cells lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
C_elegans_phenotype_ontology
WBPhenotype:0002418
spindle absent
Cells lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
GO:0005819
WB:WBPerson557
Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a cell cycle.
C_elegans_phenotype_ontology
WBPhenotype:0002419
spindle aster variant
Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a cell cycle.
WB:WBPerson557
Animals exhibit variations in the nature and/or extent of chromatin modification, including but not limited to acetylation and/or methylation of histones, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002420
chromatin modification variant
Animals exhibit variations in the nature and/or extent of chromatin modification, including but not limited to acetylation and/or methylation of histones, compared to controls.
WB:WBPaper00036090
WB:WBPerson2987
Animals exhibit increased ability to survive at low temperatures compared to controls.
cold tolerant
C_elegans_phenotype_ontology
WBPhenotype:0002421
cold resistant
Animals exhibit increased ability to survive at low temperatures compared to controls.
WB:WBPerson10321
WB:WBPerson557
Animals respond to tunicamycin at a higher concentration or a longer exposure compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002422
tunicamycin resistant
Animals respond to tunicamycin at a higher concentration or a longer exposure compared to control animals.
WB:WBPaper00036076
WB:WBPaper00037064
WB:WBPerson2987
Animals exhibit variations in response to hypoxia, low oxygen conditions, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002423
hypoxia response variant
Animals exhibit variations in response to hypoxia, low oxygen conditions, compared to controls.
WB:WBPaper00037064
WB:WBPerson2987
Animals exhibit variations in response to anoxia, trace oxygen conditions, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002424
anoxia response variant
Animals exhibit variations in response to anoxia, trace oxygen conditions, compared to controls.
WB:WBPerson557
Variations in the specific actions or reactions in response to external or internal stimuli in response to the aggregation of proteins.
C_elegans_phenotype_ontology
WBPhenotype:0002425
protein aggregation induced behavior variant
Variations in the specific actions or reactions in response to external or internal stimuli in response to the aggregation of proteins.
WB:WBPerson324
WB:WBPerson557
The duration of viability in the adult phase of the life-cycle is lowered in response to the aggregation of proteins.
C_elegans_phenotype_ontology
WBPhenotype:0002426
protein aggregation induced reduction of life span
The duration of viability in the adult phase of the life-cycle is lowered in response to the aggregation of proteins.
GO:0008340
WB:WBPaper00035872
WB:WBPerson324
WB:WBPerson557
Variations in the behavioral plasticity induced by the integration of two sensory signals in response to the aggregation of proteins.
C_elegans_phenotype_ontology
WBPhenotype:0002427
protein aggregation induced associative learning variant
Variations in the behavioral plasticity induced by the integration of two sensory signals in response to the aggregation of proteins.
WB:WBPaper00035872
WB:WBPerson324
WB:WBPerson557
Animals exhibit degeneration of the intestine, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002428
intestinal degeneration
Animals exhibit degeneration of the intestine, compared to control animals.
WB:WBPaper00041065
WB:WBPerson2987
Animals exhibit variations in the degree to which some proteins are glycosylated, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002429
protein glycosylation variant
Animals exhibit variations in the degree to which some proteins are glycosylated, compared to controls.
WB:WBPaper00042060
WB:WBPerson2987
Any variation in the extent of mitochondrial DNA damage observed compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002430
mitochondrial DNA damage variant
Any variation in the extent of mitochondrial DNA damage observed compared to controls.
WB:WBPaper00041209
WB:WBPerson712
A telomerase-independent telomere maintenance pathway that allows for strains to survive in the absence of telomerase.
ALT
C_elegans_phenotype_ontology
WBPhenotype:0002431
alternative lengthening of telomeres
A telomerase-independent telomere maintenance pathway that allows for strains to survive in the absence of telomerase.
WB:WBPaper00041021
WB:WBPerson7
Animals do not respond with sleeping behavior induced through the EGF pathway. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.
C_elegans_phenotype_ontology
stressed-induced sleep variant
WBPhenotype:0002432
EGF-induced sleep variant
Animals do not respond with sleeping behavior induced through the EGF pathway. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.
WB:WBPaper00050011
WB:WBPerson712
Animals respond with sleeping behavior induced through the EGF pathway, more rigorously than control animals. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.
C_elegans_phenotype_ontology
stressed-induced sleep resistant
WBPhenotype:0002433
EGF-induced sleep resistant
Animals respond with sleeping behavior induced through the EGF pathway, more rigorously than control animals. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.
WB:WBPaper00050011
WB:WBPerson712
Animals exhibit variations in their response to mitochondrial stress, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002434
mitochondrial stress response variant
Animals exhibit variations in their response to mitochondrial stress, compared to controls.
WB:WBPaper00027723
WB:WBPerson2987
Nematodes exposed to DNA damaging agents or conditions exhibit lower susceptibility to DNA damage than other animals.
C_elegans_phenotype_ontology
induced DNA damage resistant
WBPhenotype:0002435
less susceptibility to induced DNA damage
Nematodes exposed to DNA damaging agents or conditions exhibit lower susceptibility to DNA damage than other animals.
WB:WBPerson712
Nematodes exposed to DNA damaging agents or conditions exhibit greater susceptibility to DNA damage than other animals.
C_elegans_phenotype_ontology
induced DNA damage hypersensitive
WBPhenotype:0002436
high susceptibility to induced DNA damage
Nematodes exposed to DNA damaging agents or conditions exhibit greater susceptibility to DNA damage than other animals.
WB:WBPerson712
Animals exhibit variations in the expression of repetitive exogenous DNA compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002437
repetitive transgene expression variant
Animals exhibit variations in the expression of repetitive exogenous DNA compared to control.
WB:WBPaper00003822
WB:WBPerson2987
Animals exhibit reduced expression of repetitive exogenous DNA compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002438
repetitive transgene expression reduced
Animals exhibit reduced expression of repetitive exogenous DNA compared to control.
WB:WBPaper00003822
WB:WBPerson2987
Animals exhibit increased expression of repetitive exogenous DNA compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002439
repetitive transgene expression increased
Animals exhibit increased expression of repetitive exogenous DNA compared to control.
WB:WBPaper00003822
WB:WBPerson2987
Any perturbation that renders sperm incompetent at fertilizing an oocyte.
C_elegans_phenotype_ontology
WBPhenotype:0002440
sperm fertility defective
Any perturbation that renders sperm incompetent at fertilizing an oocyte.
WB:WBPerson2987
WB:WBPerson557
The time between two pumps of the pharynx is increased compared to control animals.
C_elegans_phenotype_ontology
pharyngeal inter-pumping interval increased
WBPhenotype:0002441
pharyngeal inter-pump interval increased
The time between two pumps of the pharynx is increased compared to control animals.
WB:WBPaper00050613
WB:WBPerson712
The duration of the contraction of the pharyngeal muscle during pumping is increased compared to controls.
C_elegans_phenotype_ontology
pharyngeal pump extended
WBPhenotype:0002442
pharyngeal pump duration increased
The duration of the contraction of the pharyngeal muscle during pumping is increased compared to controls.
WB:WBPaper00050613
WB:WBPerson712
Any variation in the specific actions or reactions of the male that are associated with the protraction of the male copulatory spicules compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002443
spicule protraction variant
Any variation in the specific actions or reactions of the male that are associated with the protraction of the male copulatory spicules compared to control.
WB:WBPerson557
Animals exhibit variations in the chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
pyrimidine base biosynthesis variant
C_elegans_phenotype_ontology
WBPhenotype:0002444
pyrimidine biosynthesis variant
Animals exhibit variations in the chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
GO:0019856
WB:WBPerson324
WB:WBPerson557
Animals have one or more extra hypodermal cells, which are present in places they are normally not found, when compared to the number and location of these cells in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002445
extra and ectopic hypodermis
Animals have one or more extra hypodermal cells, which are present in places they are normally not found, when compared to the number and location of these cells in control animals.
WB:WBPaper00025033
WB:WBPerson2987
Animals exhibit variations in pharyngeal pumping rate in response to light, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002446
pharyngeal pumping rate in response to light variant
Animals exhibit variations in pharyngeal pumping rate in response to light, compared to controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit variations in the acute pharyngeal pumping response to light, during which the pharyngeal pumping rate initially (0-5 seconds after light exposure onset) decreases in response to light, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002447
acute pumping response to light variant
Animals exhibit variations in the acute pharyngeal pumping response to light, during which the pharyngeal pumping rate initially (0-5 seconds after light exposure onset) decreases in response to light, compared to controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit an enhanced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a greater extent than in controls during the first 0-5 seconds after light exposure onset.
C_elegans_phenotype_ontology
WBPhenotype:0002448
enhanced acute pharyngeal pumping response to light
Animals exhibit an enhanced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a greater extent than in controls during the first 0-5 seconds after light exposure onset.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit a reduced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a lesser extent than in controls during the first 0-5 seconds after light exposure onset.
C_elegans_phenotype_ontology
WBPhenotype:0002449
reduced acute pharyngeal pumping response to light
Animals exhibit a reduced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a lesser extent than in controls during the first 0-5 seconds after light exposure onset.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit variations in the burst pharyngeal pumping response to light, during which the pharyngeal pumping rate slightly increases during the5-10 seconds after light exposure onset, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002450
burst pharyngeal pumping response to light
Animals exhibit variations in the burst pharyngeal pumping response to light, during which the pharyngeal pumping rate slightly increases during the5-10 seconds after light exposure onset, compared to controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit an enhanced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a greater extent than in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002451
enhanced burst pharyngeal pumping response to light
Animals exhibit an enhanced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a greater extent than in controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit a reduced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a lesser extent than in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002452
reduced burst pharyngeal pumping response to light
Animals exhibit a reduced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a lesser extent than in controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit variations in the recovery pharyngeal pumping response to light, during which the pharyngeal pumping rate slowly increases during the 0-10 seconds afterremoval of light exposure, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002453
recovery pumping response to light variant
Animals exhibit variations in the recovery pharyngeal pumping response to light, during which the pharyngeal pumping rate slowly increases during the 0-10 seconds afterremoval of light exposure, compared to controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit an enhanced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increases to a greater extent than in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002454
enhanced recovery pumping response to light
Animals exhibit an enhanced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increases to a greater extent than in controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit a reduced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increasesto a lesser extent than in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002455
reduced recovery pumping response to light
Animals exhibit a reduced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increasesto a lesser extent than in controls.
WB:WBPaper00046411
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Animals exhibit variations in the changes in calcium levels in response to light compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002456
calcium response to light variant
Animals exhibit variations in the changes in calcium levels in response to light compared to controls.
WB:WBPaper00048388
WB:WBPerson2987
WB:WBPerson557
WB:WBPerson9765
Formation in the male of the egg-laying organ of female and hermaphrodite nematodes. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
vulva in male
C_elegans_phenotype_ontology
WBPhenotype:0002457
ectopic vulva in male
Formation in the male of the egg-laying organ of female and hermaphrodite nematodes. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
WB:WBPaper00026839
WB:WBPerson2987
Any variation in the form, structure or composition of any part of an animal caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis.
Mal
C_elegans_phenotype_ontology
maternal effect morphology abnormal
WBPhenotype:0002458
maternal effect morphology variant
Any variation in the form, structure or composition of any part of an animal caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis.
WB:WBPerson557
Animals exhibit hyperinduction of expression of an antimicrobial peptide after an infection, compared to control animals.
Hipi
C_elegans_phenotype_ontology
WBPhenotype:0002459
hyperinduction of antimicrobial peptide expression after infection
Animals exhibit hyperinduction of expression of an antimicrobial peptide after an infection, compared to control animals.
WB:WBPaper00049531
WB:WBPerson168
WB:WBPerson2987
Animals exhibit no induction of expression of an antimicrobial peptide after an infection, unlike control animals.
Nipi
C_elegans_phenotype_ontology
WBPhenotype:0002460
no induction of antimicrobial peptide expression after infection
Animals exhibit no induction of expression of an antimicrobial peptide after an infection, unlike control animals.
WB:WBPaper00038424
WB:WBPaper00040946
WB:WBPaper00049531
WB:WBPerson168
WB:WBPerson2987
Pathogens exhibit decreased adherence to the surface of host animals.
C_elegans_phenotype_ontology
WBPhenotype:0002461
pathogen adherence decreased
Pathogens exhibit decreased adherence to the surface of host animals.
WB:WBPerson2987
WB:WBPerson557
Pathogens exhibit increased adherence to the surface of host animals.
C_elegans_phenotype_ontology
WBPhenotype:0002462
pathogen adherence increased
Pathogens exhibit increased adherence to the surface of host animals.
WB:WBPaper00049531
WB:WBPerson168
WB:WBPerson2987
Male animals lack a copulatory hook.
C_elegans_phenotype_ontology
WBPhenotype:0002463
hookless
Male animals lack a copulatory hook.
WB:WBPaper00045644
WB:WBPerson557
WB:WBPerson625
Male animals exhibit multiple copulatory hooks. In wild type C. elegans males, a single hook is normally present.
C_elegans_phenotype_ontology
WBPhenotype:0002464
multiple hooks
Male animals exhibit multiple copulatory hooks. In wild type C. elegans males, a single hook is normally present.
WB:WBPaper00045644
WB:WBPerson557
WB:WBPerson625
The pattern or state of ubiquitin modifications of histones varies from that of controls.
C_elegans_phenotype_ontology
histone ubiquitylation variant
WBPhenotype:0002465
histone ubiquitination variant
The pattern or state of ubiquitin modifications of histones varies from that of controls.
WB:WBPaper00053651
WB:WBPerson1370
WB:WBPerson557
Variations in the processes that incorporate methyl groups to one or more bases within RNA, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002466
RNA methylation variant
Variations in the processes that incorporate methyl groups to one or more bases within RNA, compared to control.
WB:WBPaper00049616
WB:WBPerson29150
WB:WBPerson557
Males continue to sire progeny significantly past the time reproduction stops in control animals or show a slower decline in mating efficiency compared to age-matched control males.
C_elegans_phenotype_ontology
WBPhenotype:0002467
male reproductive longevity extended
Males continue to sire progeny significantly past the time reproduction stops in control animals or show a slower decline in mating efficiency compared to age-matched control males.
WB:WBPaper00053333
WB:WBPerson557
Animals exhibit a reduction in the rate of the chemical reactions and pathways resulting in the formation of a protein, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002468
translation rate reduced
Animals exhibit a reduction in the rate of the chemical reactions and pathways resulting in the formation of a protein, compared to control.
GO:0006417
WB:WBPaper00046894
WB:WBPerson557
Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002469
plate tap habituation variant
Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control.
WB:WBPaper00041802
WB:WBPerson3192
WB:WBPerson557
Animals exhibit variations in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals.
cilium length variant
C_elegans_phenotype_ontology
WBPhenotype:0002470
cilia length variant
Animals exhibit variations in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals.
WB:WBPaper00053681
WB:WBPerson2136
WB:WBPerson557
Animals exhibit an increase in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals.
cilium length increased
C_elegans_phenotype_ontology
WBPhenotype:0002471
cilia length increased
Animals exhibit an increase in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals.
WB:WBPaper00053681
WB:WBPerson2136
WB:WBPerson557
Animals exhibit a reduction in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals.
cilium length decreased
C_elegans_phenotype_ontology
WBPhenotype:0002472
cilia length decreased
Animals exhibit a reduction in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals.
WB:WBPaper00053681
WB:WBPerson2136
WB:WBPerson557
Animals fail to undergo the cellular catabolic process in which cells digest parts of their own cytoplasm.
autophagy defective
C_elegans_phenotype_ontology
WBPhenotype:0002473
autophagy block
Animals fail to undergo the cellular catabolic process in which cells digest parts of their own cytoplasm.
GO:0006914
WB:WBPaper00046758
WB:WBPerson2242
WB:WBPerson557
Animals are less prone to infection by virus compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002474
viral resistance increased
Animals are less prone to infection by virus compared to control.
WB:WBPaper00053019
WB:WBPerson24802
WB:WBPerson557
Animals vary in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals.
pharyngeal length variant
C_elegans_phenotype_ontology
WBPhenotype:0002475
pharynx length variant
Animals vary in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals.
WB:WBPaper00049351
WB:WBPerson2693
WB:WBPerson557
Animals have an increase in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals.
pharyngeal length increased
pharynx elongation
C_elegans_phenotype_ontology
WBPhenotype:0002476
pharynx length increased
Animals have an increase in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals.
WB:WBPaper00049351
WB:WBPerson2693
WB:WBPerson557
Any variation in the subcellular localization of the ribosome compared to control. The ribosome is an intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA).
ribosome distribution variant
C_elegans_phenotype_ontology
WBPhenotype:0002477
ribosome localization variant
Any variation in the subcellular localization of the ribosome compared to control. The ribosome is an intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA).
GO:0005840
WB:WBPaper00052855
WB:WBPerson15276
WB:WBPerson557
Any variation in the cellular and molecular pathways in a neuron in response to having its axon severed compared to severing in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002478
axotomy response variant
Any variation in the cellular and molecular pathways in a neuron in response to having its axon severed compared to severing in control animals.
WB:WBPaper00053323
WB:WBPerson557
WB:WBPerson9270
Any increase in regenerative regrowth of axons compared to control animals.
axonal regeneration enhanced
C_elegans_phenotype_ontology
WBPhenotype:0002479
axon regeneration enhanced
Any increase in regenerative regrowth of axons compared to control animals.
WB:WBPaper00053323
WB:WBPerson557
WB:WBPerson9270
Animals exhibit variations in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
C_elegans_phenotype_ontology
WBPhenotype:0002480
heme levels variant
Animals exhibit variations in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0006783
WB:WBPaper00049976
WB:WBPerson16107
WB:WBPerson2987
WB:WBPerson557
Animals exhibit a decrease in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
heme levels reduced
C_elegans_phenotype_ontology
WBPhenotype:0002481
heme levels decreased
Animals exhibit a decrease in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0006783
WB:WBPaper00049976
WB:WBPerson16107
WB:WBPerson2987
WB:WBPerson557
Animals exhibit an increase in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
C_elegans_phenotype_ontology
WBPhenotype:0002482
heme levels increased
Animals exhibit an increase in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0006783
WB:WBPaper00049976
WB:WBPerson16107
WB:WBPerson2987
WB:WBPerson557
Animals are less prone to infection by a fungus compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002483
fungal resistance increased
Animals are less prone to infection by a fungus compared to control.
WB:WBPaper00046695
WB:WBPerson557
Animals exhibit variations in fluidity of cell membranes, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002484
membrane fluidity variant
Animals exhibit variations in fluidity of cell membranes, compared to control animals.
WB:WBPaper00055850
WB:WBPerson2987
Any variation in the morphological appearance of germline precursor cells compared to control animals.
C_elegans_phenotype_ontology
primordial germ cell morphology variant
WBPhenotype:0002485
germline precursor cell morphology variant
Any variation in the morphological appearance of germline precursor cells compared to control animals.
WB:WBPaper00050421
WB:WBPerson2987
Animals exhibit persistent cellular lobes of the primordial germ cells Z2 and/or Z3 at the L1 larval stage or later, in contrast to wild type animals
C_elegans_phenotype_ontology
persistent germline precursor cell lobes
WBPhenotype:0002486
persistent primordial germ cell lobes
Animals exhibit persistent cellular lobes of the primordial germ cells Z2 and/or Z3 at the L1 larval stage or later, in contrast to wild type animals
WB:WBPaper00050421
WB:WBPerson2987
WB:WBPerson35710
Animals exhibit variations in the integrity of the intestine, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002487
intestinal integrity variant
Animals exhibit variations in the integrity of the intestine, compared to controls.
WB:WBPaper00049837
WB:WBPerson2987
Animals exhibit an increase in the integrity of the intestine, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002488
intestinal integrity increased
Animals exhibit an increase in the integrity of the intestine, compared to controls.
WB:WBPaper00049837
WB:WBPerson14863
WB:WBPerson2987
Animals exhibit a reduction in the integrity of the intestine, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002489
intestinal integrity reduced
Animals exhibit a reduction in the integrity of the intestine, compared to controls.
WB:WBPerson2987
Neurons exhibit axon outgrowth in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002490
ectopic axon outgrowth
Neurons exhibit axon outgrowth in locations not normally found in controls.
WB:WBPaper00004283
WB:WBPaper00006029
WB:WBPaper00026706
WB:WBPaper00027335
WB:WBPaper00031901
WB:WBPaper00032090
WB:WBPerson2987
Neurons exhibit neurite outgrowth in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002491
ectopic neurite outgrowth
Neurons exhibit neurite outgrowth in locations not normally found in controls.
WB:WBPaper00003665
WB:WBPaper00004340
WB:WBPaper00027335
WB:WBPerson2987
Animals exhibit one or more body wall muscle cells in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002492
ectopic body wall muscle
Animals exhibit one or more body wall muscle cells in locations not normally found in controls.
WB:WBPaper00035201
WB:WBPerson2987
Animals exhibit one or more cells of a particular type in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002493
ectopic cell
Animals exhibit one or more cells of a particular type in locations not normally found in controls.
WB:WBPaper00003331
WB:WBPaper00003719
WB:WBPerson2987
Animals exhibit one or more endodermal cells in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002494
ectopic endoderm
Animals exhibit one or more endodermal cells in locations not normally found in controls.
WB:WBPaper00002871
WB:WBPaper00003645
WB:WBPerson2987
Animals exhibit one or more hypodermal cells in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002495
ectopic hypodermis
Animals exhibit one or more hypodermal cells in locations not normally found in controls.
WB:WBPaper00025033
WB:WBPerson2987
Animals exhibit one or more neurons in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002496
ectopic neuron
Animals exhibit one or more neurons in locations not normally found in controls.
WB:WBPaper00000635
WB:WBPaper00027335
WB:WBPerson2987
Animals exhibit one or more pharyngeal muscle cells in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002497
ectopic pharyngeal muscle
Animals exhibit one or more pharyngeal muscle cells in locations not normally found in controls.
WB:WBPaper00003574
WB:WBPaper00003645
WB:WBPerson2987
Animals exhibit one or more organs of a particular type in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002498
ectopic organ
Animals exhibit one or more organs of a particular type in locations not normally found in controls.
WB:WBPaper00031604
WB:WBPerson2987
Animals exhibit one or more vulvae in locations not normally found in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002499
ectopic vulva
Animals exhibit one or more vulvae in locations not normally found in controls.
WB:WBPaper00031604
WB:WBPerson2987
One or more cells exhibit one or more cleavage furrows in locations not normally found in control cells.
C_elegans_phenotype_ontology
WBPhenotype:0002500
ectopic cleavage furrow
One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
C_elegans_phenotype_ontology
WBPhenotype:0002501
ectopic cleavage furrow early emb
One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WB:WBPaper00005599
WB:WBPaper00006061
WB:WBPaper00030892
WB:WBPaper00033469
WB:WBPerson2987
Animals exhibit an increase in the covalent addition of an acetyl group to one or more native amino acid side chains in proteins.
C_elegans_phenotype_ontology
WBPhenotype:0002502
protein acetylation increased
Animals exhibit an increase in the covalent addition of an acetyl group to one or more native amino acid side chains in proteins.
WB:WBPaper00046534
WB:WBPerson113
WB:WBPerson2987
Animals exhibit an increase the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination.
C_elegans_phenotype_ontology
WBPhenotype:0002503
meiotic DNA double strand break formation increased
Animals exhibit an increase the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination.
WB:WBPaper00046534
WB:WBPerson113
WB:WBPerson2987
Infected animals exhibit a reduction in the release of pathogens back into the environment, compared to control.
spore shedding reduced
C_elegans_phenotype_ontology
WBPhenotype:0002504
pathogen release reduced
Infected animals exhibit a reduction in the release of pathogens back into the environment, compared to control.
WB:WBPaper00040246
WB:WBPaper00045292
WB:WBPerson2987
WB:WBPerson3965
Infected animals exhibit variations in the clearance of pathogen infection compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002505
pathogen infection clearance variant
Infected animals exhibit variations in the clearance of pathogen infection compared to controls.
WB:WBPaper00044624
WB:WBPerson2706
WB:WBPerson2987
Infected animals exhibit an increased rate of clearance of pathogen infection compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002506
pathogen infection clearance rate increased
Infected animals exhibit an increased rate of clearance of pathogen infection compared to controls.
WB:WBPaper00044624
WB:WBPerson2706
WB:WBPerson2987
Infected animals exhibit a decreased rate of clearance of pathogen infection compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002507
pathogen infection clearance rate decreased
Infected animals exhibit a decreased rate of clearance of pathogen infection compared to controls.
WB:WBPaper00044624
WB:WBPerson2706
WB:WBPerson2987
Animals produce an excess number of neurons compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002508
extra neuron
Animals produce an excess number of neurons compared to controls.
WB:WBPaper00053165
WB:WBPerson2987
WB:WBPerson3252
Animals produce an excess number of dopaminergic neurons compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002509
extra dopaminergic neuron
Animals produce an excess number of dopaminergic neurons compared to controls.
WB:WBPaper00053165
WB:WBPerson2987
WB:WBPerson3252
Animals exhibit fewer neurons compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002510
fewer neurons
Animals exhibit fewer neurons compared to control animals.
WB:WBPaper00053165
WB:WBPerson2987
WB:WBPerson3252
Animals exhibit fewer glutamatergic neurons compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002511
fewer glutamatergic neurons
Animals exhibit fewer glutamatergic neurons compared to control animals.
WB:WBPaper00053165
WB:WBPerson2987
WB:WBPerson3252
Variations in behavior that is dependent upon the sensation of temperature, compared to control.
thermosensory behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002512
thermosensory behavior variant
Variations in behavior that is dependent upon the sensation of temperature, compared to control.
GO:0040040
WB:WBPerson2987
Any variation in the directed movement of a worm in response to a specific temperature gradient compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002513
thermotaxis variant
Any variation in the directed movement of a worm in response to a specific temperature gradient compared to control.
GO:0043052
WB:WBPerson2987
Animals do not exhibit backward locomotion under conditions that induce backward locomotion in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002514
backing absent
Animals do not exhibit backward locomotion under conditions that induce backward locomotion in control animals.
WB:WBPerson261
WB:WBPerson2987
Animals exhibit a defective response to pathogens.
C_elegans_phenotype_ontology
WBPhenotype:0002515
organism pathogen response defective
Animals exhibit a defective response to pathogens.
WB:WBPaper00055957
WB:WBPerson2987
WB:WBPerson919
Animals exhibit variations, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Variations in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect variations in neuromuscular efficacy of locomotion.
C_elegans_phenotype_ontology
WBPhenotype:0002516
burrowing assay distance abnormal
Animals exhibit variations, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Variations in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect variations in neuromuscular efficacy of locomotion.
WB:WBPaper00046657
WB:WBPaper00056369
WB:WBPerson2987
WB:WBPerson9270
Animals exhibit a reduction, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Reductions in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect deficits in neuromuscular efficacy of locomotion.
C_elegans_phenotype_ontology
WBPhenotype:0002517
burrowing assay distance reduced
Animals exhibit a reduction, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Reductions in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect deficits in neuromuscular efficacy of locomotion.
WB:WBPaper00046657
WB:WBPaper00056369
WB:WBPerson2987
WB:WBPerson9270
The length of one or more axons is abnormal compared to the length of the corresponding axon(s) in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002518
axon length abnormal
The length of one or more axons is abnormal compared to the length of the corresponding axon(s) in control animals.
WB:WBPaper00056369
WB:WBPerson2987
WB:WBPerson9270
The length of one or more axons is reduced compared to the length of the corresponding axon(s) in control animals.
short axon
C_elegans_phenotype_ontology
WBPhenotype:0002519
axon length reduced
The length of one or more axons is reduced compared to the length of the corresponding axon(s) in control animals.
WB:WBPaper00056369
WB:WBPerson2987
WB:WBPerson9270
One or more cells exhibit variations in the morphology of one or more gap junction plaques, sets of associated gap junctions, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002520
gap junction plaque morphology abnormal
One or more cells exhibit variations in the morphology of one or more gap junction plaques, sets of associated gap junctions, compared to controls.
WB:WBPaper00049389
WB:WBPerson2987
WB:WBPerson30255
One or more cells exhibit an increase in number of gap junction plaques, sets of associated gap junctions, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002521
gap junction plaque number increased
One or more cells exhibit an increase in number of gap junction plaques, sets of associated gap junctions, compared to controls.
WB:WBPaper00049389
WB:WBPerson2987
WB:WBPerson30255
Animals exhibit variations in the recovery from L1 larvae developmental arrest in response to a lack of food (starvation) available in the environment.
C_elegans_phenotype_ontology
WBPhenotype:0002522
starvation-induced L1 arrest recovery abnormal
Animals exhibit variations in the recovery from L1 larvae developmental arrest in response to a lack of food (starvation) available in the environment.
WB:WBPaper00049938
WB:WBPerson2987
WB:WBPerson6498
Animals exhibit a slow recovery from starvation-induced L1 arrest, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002523
slow recovery from starvation-induced L1 arrest
Animals exhibit a slow recovery from starvation-induced L1 arrest, compared to controls.
WB:WBPaper00049938
WB:WBPerson2987
WB:WBPerson34124
WB:WBPerson6498
Animals are more sensitive to the depletion of molybdenum cofactor from the diet compared to control animals.
dependent on dietary molybdenum cofactor
C_elegans_phenotype_ontology
WBPhenotype:0002524
molybdenum cofactor depletion hypersensitive
Animals are more sensitive to the depletion of molybdenum cofactor from the diet compared to control animals.
WB:WBPaper00056452
WB:WBPerson2987
Animals exhibit variations in their response to diet, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002525
diet response variant
Animals exhibit variations in their response to diet, compared to controls.
WB:WBPaper00024451
WB:WBPaper00026641
WB:WBPaper00032936
WB:WBPaper00045849
WB:WBPaper00056452
WB:WBPerson2987
Animals exhibit variations in the response to the depletion of molybdenum cofactor from the diet compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002526
response to molybdenum cofactor depletion abnormal
Animals exhibit variations in the response to the depletion of molybdenum cofactor from the diet compared to control animals.
WB:WBPaper00056452
WB:WBPerson2987
Animals in the dauer larval stage exhibit variations in their physiology (any biological process including but not limited to development, behavior, or metabolism) compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002527
dauer larva physiology variant
Animals in the dauer larval stage exhibit variations in their physiology (any biological process including but not limited to development, behavior, or metabolism) compared to controls.
WB:WBPaper00004052
WB:WBPerson2987
Animals (or cells) exhibit defects in the ability to produce mature microRNAs (miRNAs) from a miRNA locus. The defects could be at the level of miRNA transcription, pri-miRNA processing, and/or pre-miRNA processing.
C_elegans_phenotype_ontology
WBPhenotype:0002528
miRNA biogenesis defective
Animals (or cells) exhibit defects in the ability to produce mature microRNAs (miRNAs) from a miRNA locus. The defects could be at the level of miRNA transcription, pri-miRNA processing, and/or pre-miRNA processing.
WB:WBPaper00041677
WB:WBPerson2987
WB:WBPerson5649
Animals exhibit defects or impairments in the functioning of the proteasome.
C_elegans_phenotype_ontology
WBPhenotype:0002529
proteasome defective
Animals exhibit defects or impairments in the functioning of the proteasome.
WB:WBPaper00056554
WB:WBPerson2987
WB:WBPerson5649
The level of phosphatidylserine exposed on the external axonal membrane following transection (axotomy) is changed compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002530
axotomy-induced phosphatidylserine exposure abnormal
The level of phosphatidylserine exposed on the external axonal membrane following transection (axotomy) is changed compared to controls.
WB:WBPaper00053570
WB:WBPerson2987
WB:WBPerson9270
Animals exhibit variations in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded.
C_elegans_phenotype_ontology
WBPhenotype:0002531
allophagy abnormal
Animals exhibit variations in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded.
WB:WBPaper00040312
WB:WBPaper00041104
WB:WBPaper00053507
WB:WBPerson2987
WB:WBPerson3859
Animals exhibit defects in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded.
C_elegans_phenotype_ontology
WBPhenotype:0002532
allophagy defective
Animals exhibit defects in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded.
WB:WBPaper00053507
WB:WBPerson2987
WB:WBPerson3859
Animals exhibit variations in the expression of one or more known, endogenous, antimicrobial genes, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002534
antimicrobial gene expression variant
Animals exhibit variations in the expression of one or more known, endogenous, antimicrobial genes, compared to controls.
WB:WBPaper00031865
WB:WBPerson2987
Animals exhibit variations in the extent to which one or more sensory neurons associated with sensilla (typically one or more amphids and/or phasmids) take up dye from the environment, compared to controls. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO.
Dyf
dye filling abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002535
dye filling defect
Animals exhibit variations in the extent to which one or more sensory neurons associated with sensilla (typically one or more amphids and/or phasmids) take up dye from the environment, compared to controls. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO.
WB:WBPaper00000793
WB:WBPerson2987
Animals exhibit germ cells with a number of P granules that differs from control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002536
P granule number abnormal
Animals exhibit germ cells with a number of P granules that differs from control animals.
WB:WBPaper00044160
WB:WBPerson2987
WB:WBPerson557
Animals exhibit germ cells with a reduced number of P granules compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002537
P granule number reduced
Animals exhibit germ cells with a reduced number of P granules compared to control animals.
WB:WBPaper00044160
WB:WBPerson2987
WB:WBPerson557
Any variation in the series of molecular signals in which the spermatheca uses calcium ions to convert an extracellular signal into a response, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002538
calcium signaling in spermatheca variant
Any variation in the series of molecular signals in which the spermatheca uses calcium ions to convert an extracellular signal into a response, compared to control.
WB:WBPaper00056137
WB:WBPerson2987
WB:WBPerson30989
Animals exhibit an increase in the expression of one or more known, endogenous, antimicrobial genes, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002539
antimicrobial gene expression increased
Animals exhibit an increase in the expression of one or more known, endogenous, antimicrobial genes, compared to controls.
WB:WBPaper00047109
WB:WBPerson15627
WB:WBPerson2987
Animals exhibit a reduced rate of lawn/food leaving events, compared to controls.
food leaving reduced
C_elegans_phenotype_ontology
WBPhenotype:0002540
lawn leaving reduced
Animals exhibit a reduced rate of lawn/food leaving events, compared to controls.
WB:WBPaper00053007
WB:WBPerson262
WB:WBPerson2987
Programmed cell death of germ cells caused by exposure to ionizing energy occurs to a lesser extent than it does in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002541
radiation induced germ cell apoptosis resistant
Programmed cell death of germ cells caused by exposure to ionizing energy occurs to a lesser extent than it does in control animals.
WB:WBPaper00032243
WB:WBPaper00032356
WB:WBPerson2987
Cells exhibit specific regions of chromatin (e.g. an integrated array reporter) that localize to different regions within the nucleus, compared to controls.
intranuclear chromatin localization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002542
intranuclear chromatin localization variant
Cells exhibit specific regions of chromatin (e.g. an integrated array reporter) that localize to different regions within the nucleus, compared to controls.
WB:WBPaper00056796
WB:WBPerson2987
WB:WBPerson32254
Animals accumulate a greater number of mitochondrial genetic lesions than control animals in the absence of an externally controlled mutagen.
C_elegans_phenotype_ontology
WBPhenotype:0002543
spontaneous mitochondrial DNA mutation rate increased
Animals accumulate a greater number of mitochondrial genetic lesions than control animals in the absence of an externally controlled mutagen.
WB:WBPaper00053883
WB:WBPerson2987
WB:WBPerson31184
Normally beneficial (or otherwise harmless, non-pathogenic) commensal Enterobacter bacteria, for example Enterobacter cloacae, become pathogenic to animals, unlike in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002544
hypersensitive to Enterobacter commensals
Normally beneficial (or otherwise harmless, non-pathogenic) commensal Enterobacter bacteria, for example Enterobacter cloacae, become pathogenic to animals, unlike in control animals.
WB:WBPaper00056139
WB:WBPerson2987
WB:WBPerson3878
Animals exhibit variations in their response to bacteria (pathogenic or non-pathogenic), compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002545
response to bacteria variant
Animals exhibit variations in their response to bacteria (pathogenic or non-pathogenic), compared to controls.
WB:WBPaper00056139
WB:WBPerson2987
WB:WBPerson3878
Animals exhibit variations in the load of bacteria, of a particular clade or in general, in the gut, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002546
bacterial load in gut variant
Animals exhibit variations in the load of bacteria, of a particular clade or in general, in the gut, compared to controls.
WB:WBPaper00056139
WB:WBPerson2987
WB:WBPerson3878
Animals exhibit a greater abundance of bacteria of the Enterobacteriaceae family in the gut, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002547
gut Enterobacteriaceae bloom
Animals exhibit a greater abundance of bacteria of the Enterobacteriaceae family in the gut, compared to controls.
WB:WBPaper00056139
WB:WBPerson2987
WB:WBPerson3878
Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves.
conflicted kinker
C_elegans_phenotype_ontology
WBPhenotype:0002548
kinker from conflicting forward and backward body bend propagation
Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves.
WB:WBPaper00040432
WB:WBPerson2987
WB:WBPerson720
Animals exhibit an increase in the rate at which spontaneous backward locomotion is initiated compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002549
increased frequency of spontaneous reversal initiation
Animals exhibit an increase in the rate at which spontaneous backward locomotion is initiated compared to control.
WB:WBPaper00040432
WB:WBPerson2987
WB:WBPerson720
Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves, and over time has a tendency to move slowly backward due to a dominating reversal neural circuit.
C_elegans_phenotype_ontology
WBPhenotype:0002550
conflicted kinker with gradual backward movement
Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves, and over time has a tendency to move slowly backward due to a dominating reversal neural circuit.
WB:WBPaper00040432
WB:WBPerson2987
WB:WBPerson720
A phenotype affecting a particular anatomical entity.
C_elegans_phenotype_ontology
WBPhenotype:0002551
anatomical phenotype
A phenotype affecting a particular anatomical entity.
WB:WBPerson2987
A phenotype affecting a particular cell.
C_elegans_phenotype_ontology
WBPhenotype:0002552
cell phenotype
A phenotype affecting a particular cell.
WB:WBPerson2987
A phenotype affecting a particular organ.
C_elegans_phenotype_ontology
WBPhenotype:0002553
organ phenotype
A phenotype affecting a particular organ.
WB:WBPerson2987
A phenotype affecting a particular organ system.
C_elegans_phenotype_ontology
WBPhenotype:0002554
organ system phenotype
A phenotype affecting a particular organ system.
WB:WBPerson2987
A phenotype affecting the whole organism.
C_elegans_phenotype_ontology
WBPhenotype:0002555
organismal phenotype
A phenotype affecting the whole organism.
WB:WBPerson2987
A phenotype affecting a particular tissue.
C_elegans_phenotype_ontology
WBPhenotype:0002556
tissue phenotype
A phenotype affecting a particular tissue.
WB:WBPerson2987
A phenotype affecting a particular body region.
C_elegans_phenotype_ontology
WBPhenotype:0002557
body region phenotype
A phenotype affecting a particular body region.
WB:WBPerson2987
A phenotype affecting a particular extracellular component.
C_elegans_phenotype_ontology
WBPhenotype:0002558
extracellular component phenotype
A phenotype affecting a particular extracellular component.
WB:WBPerson2987
Animals exhibit abnormalities in their burrowing behavior, in which animals burrow into a solid medium, such as agar, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002559
burrowing abnormal
Animals exhibit abnormalities in their burrowing behavior, in which animals burrow into a solid medium, such as agar, compared to control animals.
WB:WBPerson2987
Greater quantities of worms burrow into and stay below the surface of the agar when high densities of nematodes are maintained on agar compared to controls (Hodgkin and Doniach, 1997).
C_elegans_phenotype_ontology
WBPhenotype:0002560
burrowing in response to high population density increased
Greater quantities of worms burrow into and stay below the surface of the agar when high densities of nematodes are maintained on agar compared to controls (Hodgkin and Doniach, 1997).
WB:WBPaper00058743
WB:WBPerson2987
WB:WBPerson712
WB:WBPaper00002770
Cells exhibit defects in the homotypic fusion of endosomes.
WBPhenotype:0001638
C_elegans_phenotype_ontology
WBPhenotype:0002561
homotypic endosome fusion defective
Cells exhibit defects in the homotypic fusion of endosomes.
GO:0034058
WB:WBPaper00029049
WB:WBPerson2987
Cells exhibit variations or abnormalities in their maintenance of lysosome function, compared to controls.
WBPhenotype:0001784
C_elegans_phenotype_ontology
WBPhenotype:0002562
lysosome homeostasis abnormal
Cells exhibit variations or abnormalities in their maintenance of lysosome function, compared to controls.
WB:WBPaper00029049
WB:WBPerson2987
Animals exhibit variations in any physical or chemical process required for the neuron to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals.
WBPhenotype:0000991
neuron physiology abnormal
neuron physiology variant
C_elegans_phenotype_ontology
WBPhenotype:0002563
neuron physiology phenotype
Animals exhibit variations in any physical or chemical process required for the neuron to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals.
WB:WBPerson2987
Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms, compared to controls.
associative memory abnormal
associative memory variant
C_elegans_phenotype_ontology
WBPhenotype:0002564
associative memory phenotype
Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms, compared to controls.
WB:WBPaper00036296
WB:WBPerson2987
Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms, compared to controls.
olfactory memory abnormal
olfactory memory variant
C_elegans_phenotype_ontology
WBPhenotype:0002565
associative olfactory memory phenotype
Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms, compared to controls.
WB:WBPaper00036296
WB:WBPerson2987
WB:WBPerson3142
Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s).
long-term associative olfactory memory abnormal
long-term associative olfactory memory variant
C_elegans_phenotype_ontology
WBPhenotype:0002566
long-term associative olfactory memory phenotype
Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s).
WB:WBPaper00036296
WB:WBPerson2987
WB:WBPerson3142
Animals are deficient in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s).
C_elegans_phenotype_ontology
WBPhenotype:0002567
long-term associative olfactory memory defective
Animals are deficient in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s).
WB:WBPaper00036296
WB:WBPerson2987
WB:WBPerson3142
Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s).
long-term associative memory abnormal
long-term associative memory variant
C_elegans_phenotype_ontology
WBPhenotype:0002568
long-term associative memory phenotype
Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s).
WB:WBPaper00036296
WB:WBPerson2987
WB:WBPerson3142
Any variation in the progression of the hypodermis over time, from its formation to its mature state compared to control.
hypodermal development abnormal
hypodermal development variant
hypodermis development abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002569
hypodermis development variant
Any variation in the progression of the hypodermis over time, from its formation to its mature state compared to control.
WB:WBPerson2987
Cessation of development during the gastrulation stage of embryonic development. In C. elegans, gastrulation occurs 100-290 minutes after first cleavage at 20 degrees Centigrade when the embryo develops from 28 cells to 421 cells (during the proliferating embryo life stage).
C_elegans_phenotype_ontology
WBPhenotype:0002570
embryonic arrest during gastrulation
Cessation of development during the gastrulation stage of embryonic development. In C. elegans, gastrulation occurs 100-290 minutes after first cleavage at 20 degrees Centigrade when the embryo develops from 28 cells to 421 cells (during the proliferating embryo life stage).
WB:WBPerson2987
WB:WBPerson6609
Embryos exhibit a failure to enclose the anterior embryo region with hypodermis during the comma to early elongation stage of embryonic development.
C_elegans_phenotype_ontology
WBPhenotype:0002571
anterior enclosure defective
Embryos exhibit a failure to enclose the anterior embryo region with hypodermis during the comma to early elongation stage of embryonic development.
WB:WBPerson2987
WB:WBPerson6609
Animals exhibit variations in mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control.
mitophagy variant
C_elegans_phenotype_ontology
WBPhenotype:0002572
mitophagy abnormal
Animals exhibit variations in mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control.
WB:WBPaper00056229
WB:WBPerson27070
WB:WBPerson2987
Animals exhibit reduced levels of mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002573
mitophagy reduced
Animals exhibit reduced levels of mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control.
WB:WBPaper00056229
WB:WBPerson27070
WB:WBPerson2987
Animals exhibit abnormal amounts of variation in gene expression level between individual animals, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002574
gene expression level variation abnormal
Animals exhibit abnormal amounts of variation in gene expression level between individual animals, compared to control.
WB:WBPaper00050756
WB:WBPerson2987
WB:WBPerson5662
Animals exhibit abnormal gene expression levels, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002575
gene expression level abnormal
Animals exhibit abnormal gene expression levels, compared to control.
WB:WBPerson2987
Animals exhibit reduced amounts of variation in gene expression level between individual animals, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002576
gene expression level variation reduced
Animals exhibit reduced amounts of variation in gene expression level between individual animals, compared to control.
WB:WBPaper00050756
WB:WBPerson2987
WB:WBPerson5662
Animals exhibit variations in the composition of basement membranes, compared to control animals.
basement membrane composition abnormal
basement membrane composition variant
C_elegans_phenotype_ontology
WBPhenotype:0002577
basement membrane composition phenotype
Animals exhibit variations in the composition of basement membranes, compared to control animals.
WB:WBPaper00057139
WB:WBPerson2987
WB:WBPerson32869
Animals exhibit variations in the amount of laminin in basement membranes, compared to control animals.
basement membrane laminin level abnormal
basement membrane laminin level variant
C_elegans_phenotype_ontology
WBPhenotype:0002578
basement membrane laminin level phenotype
Animals exhibit variations in the amount of laminin in basement membranes, compared to control animals.
WB:WBPaper00057139
WB:WBPerson2987
WB:WBPerson32869
Animals exhibit variations in the amount of type IV collagen in basement membranes, compared to control animals.
basement membrane type IV collagen level abnormal
basement membrane type IV collagen level variant
C_elegans_phenotype_ontology
WBPhenotype:0002579
basement membrane type IV collagen level phenotype
Animals exhibit variations in the amount of type IV collagen in basement membranes, compared to control animals.
WB:WBPaper00057139
WB:WBPerson2987
WB:WBPerson32869
One or more cells exhibit changes in the variability of cell position, compared to controls.
cell position variability abnormal
cell position variability variant
C_elegans_phenotype_ontology
WBPhenotype:0002580
cell position variability phenotype
One or more cells exhibit changes in the variability of cell position, compared to controls.
WB:WBPaper00056010
WB:WBPerson13958
WB:WBPerson2987
One or more cells exhibit increases in the variability of cell position, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002581
cell position variability increased
One or more cells exhibit increases in the variability of cell position, compared to controls.
WB:WBPaper00056010
WB:WBPerson13958
WB:WBPerson2987
Animals exhibit variations in miniature inhibitory post-synaptic currents (mIPSC), compared to controls.
mIPSC abnormal
mIPSC phenotype
mIPSC variant
miniature inhibitory post-synaptic current abnormal
miniature inhibitory post-synaptic current variant
C_elegans_phenotype_ontology
WBPhenotype:0002582
miniature inhibitory post-synaptic current phenotype
Animals exhibit variations in miniature inhibitory post-synaptic currents (mIPSC), compared to controls.
WB:WBPaper00048837
WB:WBPerson18607
WB:WBPerson2987
Animals exhibit increased amplitude of miniature inhibitory post-synaptic currents (mIPSC), compared to controls.
mIPSC amplitude increased
C_elegans_phenotype_ontology
WBPhenotype:0002583
miniature inhibitory post-synaptic current amplitude increased
Animals exhibit increased amplitude of miniature inhibitory post-synaptic currents (mIPSC), compared to controls.
WB:WBPaper00048837
WB:WBPerson18607
WB:WBPerson2987
Animals survive longer, or do not respond to the same degree as control animals under similar conditions of bisphenol A exposure.
C_elegans_phenotype_ontology
WBPhenotype:0002584
bisphenol A resistant
Animals survive longer, or do not respond to the same degree as control animals under similar conditions of bisphenol A exposure.
WB:WBPaper00024241
WB:WBPerson557
Pristionchus pacificus: Animals exhibit abnormal predatory behavior, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002585
predatory behavior abnormal
Pristionchus pacificus: Animals exhibit abnormal predatory behavior, compared to controls.
WB:WBPaper00053031
WB:WBPerson2987
WB:WBPerson38478
Pristionchus pacificus: Animals exhibit reduced predatory feeding behavior, indicated by reduced predation success, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002586
reduced predatory feeding behavior
Pristionchus pacificus: Animals exhibit reduced predatory feeding behavior, indicated by reduced predation success, compared to controls.
WB:WBPaper00053031
WB:WBPerson2987
WB:WBPerson38478
Animals are impaired in their burrowing ability compared to control animals in a Pluronic gel-based burrowing assay.
C_elegans_phenotype_ontology
WBPhenotype:0002587
Pluronic gel burrowing impaired
Animals are impaired in their burrowing ability compared to control animals in a Pluronic gel-based burrowing assay.
WB:WBPaper00058750
WB:WBPerson2987
WB:WBPerson43910
Animals exhibit variations or abnormalities in the structure, integrity, function, or quality of basement membranes, compared to controls.
basement membrane abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002588
basement membrane phenotype
Animals exhibit variations or abnormalities in the structure, integrity, function, or quality of basement membranes, compared to controls.
WB:WBPaper00037647
Animals exhibit a reduction in neuron degeneration, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002589
neuron degeneration reduced
Animals exhibit a reduction in neuron degeneration, compared to control animals.
WB:WBPerson2987
WB:WBPerson58
The linker cell of male animals becomes detached from the rest of the male gonad.
C_elegans_phenotype_ontology
WBPhenotype:0002590
linker cell detached
The linker cell of male animals becomes detached from the rest of the male gonad.
WB:WBPaper00046064
WB:WBPerson2987
One or more neurons of the animal exhibit one or more dendrites with reduced length compared to the corresponding dendrites in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002591
dendrite length reduced
One or more neurons of the animal exhibit one or more dendrites with reduced length compared to the corresponding dendrites in control animals.
WB:WBPaper00033050
WB:WBPerson2987
Animals exhibit variations in their response to changes in gravitational force, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002592
organism response to gravitational force abnormal
Animals exhibit variations in their response to changes in gravitational force, compared to control animals.
WB:WBPaper00030928
WB:WBPerson2987
Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s).
C_elegans_phenotype_ontology
WBPhenotype:0002593
short term plate tap habituation variant
Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s).
WB:WBPaper00006159
WB:WBPerson2987
Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s).
C_elegans_phenotype_ontology
WBPhenotype:0002594
long term plate tap habituation variant
Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s).
WB:WBPaper00006159
WB:WBPerson2987
The reduction in brood size caused by sleep deprivation is enhanced, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002595
sleep deprivation-induced brood size reduction enhanced
The reduction in brood size caused by sleep deprivation is enhanced, compared to controls.
WB:WBPaper00052970
WB:WBPerson2987
The reduction in brood size caused by sleep deprivation is suppressed, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002596
sleep deprivation-induced brood size reduction suppressed
The reduction in brood size caused by sleep deprivation is suppressed, compared to controls.
WB:WBPaper00052970
WB:WBPerson2987
Variations in the behavioral plasticity induced by the integration of two sensory signals (one of which is gustation (taste)) compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype have an abnormal response to the trained stimuli compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002597
gustatory learning abnormal
Variations in the behavioral plasticity induced by the integration of two sensory signals (one of which is gustation (taste)) compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype have an abnormal response to the trained stimuli compared to controls.
WB:WBPaper00059641
WB:WBPerson2987
Variations in the aversion of animals to substances sensed by gustation (taste) previously associated with an aversive stimuli during a gustation training protocol, compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype will not exhibit the same aversion to the substance as compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002598
gustatory aversive learning abnormal
Variations in the aversion of animals to substances sensed by gustation (taste) previously associated with an aversive stimuli during a gustation training protocol, compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype will not exhibit the same aversion to the substance as compared to control animals.
WB:WBPaper00059641
WB:WBPerson2987
Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s).
long-term habituation abnormal
long-term habituation variant
C_elegans_phenotype_ontology
WBPhenotype:0002599
long-term habituation phenotype
Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s).
WB:WBPaper00041586
WB:WBPerson2987
Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s).
short-term habituation abnormal
short-term habituation variant
C_elegans_phenotype_ontology
WBPhenotype:0002600
short-term habituation phenotype
Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s).
WB:WBPaper00041586
WB:WBPerson2987
Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the short term, compared to controls. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s).
short-term associative memory abnormal
short-term associative memory variant
C_elegans_phenotype_ontology
WBPhenotype:0002601
short-term associative memory phenotype
Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the short term, compared to controls. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s).
WB:WBPaper00041586
WB:WBPerson2987
Animals exhibit a decrease in the rate at which spontaneous backward locomotion is initiated compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002602
reduced frequency of spontaneous reversal initiation
Animals exhibit a decrease in the rate at which spontaneous backward locomotion is initiated compared to control.
WB:WBPaper00049647
WB:WBPerson2987
Animals exhibit an abnormal response to toxic proteins, either via exposure in the environment or expressed within the organism, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002603
protein toxicity response abnormal
Animals exhibit an abnormal response to toxic proteins, either via exposure in the environment or expressed within the organism, compared to controls.
WB:WBPaper00059748
WB:WBPerson2987
Animals exhibit an abnormal response to toxic dipeptide repeat proteins, either via exposure in the environment or expressed within the organism, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002604
dipeptide repeat protein toxicity abnormal
Animals exhibit an abnormal response to toxic dipeptide repeat proteins, either via exposure in the environment or expressed within the organism, compared to controls.
WB:WBPaper00059748
WB:WBPerson2987
Normally toxic dipeptide repeat proteins appear to be less toxic to animals, compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002605
dipeptide repeat protein toxicity suppressed
Normally toxic dipeptide repeat proteins appear to be less toxic to animals, compared to control animals.
WB:WBPaper00059748
WB:WBPerson2987
Animals exhibit reduced necrotic cell death, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002606
necrotic cell death decreased
Animals exhibit reduced necrotic cell death, compared to controls.
WB:WBPaper00028466
WB:WBPaper00059770
WB:WBPerson2987
One or more cellular nuclei exhibit an abnormal size, compared to controls.
nuclear size phenotype
nuclear size variant
C_elegans_phenotype_ontology
WBPhenotype:0002607
nuclear size abnormal
One or more cellular nuclei exhibit an abnormal size, compared to controls.
WB:WBPaper00042522
WB:WBPerson2987
A body elongation defect in which embryos develop abnormally bulged dorsal surfaces.
Hmp
C_elegans_phenotype_ontology
WBPhenotype:0002608
"After standard ethylmethane sulfonate mutagenesis, we screened directly for mutant embryos that are defective in body elongation. We isolated 13 recessive, zygotic-lethal mutants that, in addition to failing to elongate properly, show abnormally bulged dorsal surfaces (Fig. 1B). We call this novel phenotype Hmp (humpback); this phenotype contrasts with previously described elongation-defective Pat mutants that display bulges at variable positions (Williams and Waterston, 1994)."
humpback
A body elongation defect in which embryos develop abnormally bulged dorsal surfaces.
WB:WBPaper00003046
"After standard ethylmethane sulfonate mutagenesis, we screened directly for mutant embryos that are defective in body elongation. We isolated 13 recessive, zygotic-lethal mutants that, in addition to failing to elongate properly, show abnormally bulged dorsal surfaces (Fig. 1B). We call this novel phenotype Hmp (humpback); this phenotype contrasts with previously described elongation-defective Pat mutants that display bulges at variable positions (Williams and Waterston, 1994)."
WB:WBPaper00003046
An anterior enclosure defect in which the anterior portion of the embryo, unenclosed by the hypodermis, bulges to form a hammerhead shape.
Hmr
C_elegans_phenotype_ontology
"However, in the remaining hmr-1 mutants the hypodermis fails to fully enclose the embryo. We call this phenotype Hmr (hammerhead; see Fig. 1F)."
hammerhead
An anterior enclosure defect in which the anterior portion of the embryo, unenclosed by the hypodermis, bulges to form a hammerhead shape.
WB:WBPaper00003046
WB:WBPerson2987
Hmr
WB:WBPaper00003046
"However, in the remaining hmr-1 mutants the hypodermis fails to fully enclose the embryo. We call this phenotype Hmr (hammerhead; see Fig. 1F)."
WB:WBPaper00003046
Apoptosis occurs in cells or cell types that do not undergo apoptosis in controls.
C_elegans_phenotype_ontology
WBPhenotype:0002610
ectopic apoptosis
Apoptosis occurs in cells or cell types that do not undergo apoptosis in controls.
WB:WBPaper00044285
WB:WBPerson2987
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is impaired.
C_elegans_phenotype_ontology
WBPhenotype:0002611
meiotic cytoplasmic streaming defective
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is impaired.
WB:WBPaper00050908
WB:WBPerson2987
WB:WBPerson3569
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is abnormal compared to control.
cytoplasmic streaming abnormal
cytoplasmic streaming variant
C_elegans_phenotype_ontology
WBPhenotype:0002612
cytoplasmic streaming phenotype
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is abnormal compared to control.
GO:0099636
WB:WBPaper00050908
WB:WBPerson2987
WB:WBPerson3569
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is abnormal compared to control.
meiotic cytoplasmic streaming abnormal
meiotic cytoplasmic streaming variant
C_elegans_phenotype_ontology
WBPhenotype:0002613
meiotic cytoplasmic streaming phenotype
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is abnormal compared to control.
WB:WBPaper00050908
WB:WBPerson2987
WB:WBPerson3569
Genes normally silenced within heterochromatin are abnoramally de-repressed and exhibit expression, unlike controls.
C_elegans_phenotype_ontology
WBPhenotype:0002614
derepression of heterchromatic gene silencing
Genes normally silenced within heterochromatin are abnoramally de-repressed and exhibit expression, unlike controls.
WB:WBPaper00059527
WB:WBPerson2439
WB:WBPerson2987
Animals accumulate vacuoles in an abnormal manner in cells, tissues, and/or organs of the animal.
C_elegans_phenotype_ontology
WBPhenotype:0002615
abnormal accumulation of vacuoles
Animals accumulate vacuoles in an abnormal manner in cells, tissues, and/or organs of the animal.
WB:WBPaper00041673
WB:WBPerson2987
Cells exhibit an abnormal intracellular level (amount) of calcium, compared to controls.
cellular calcium level phenotype
cellular calcium level variant
C_elegans_phenotype_ontology
WBPhenotype:0002616
cellular calcium level abnormal
Cells exhibit an abnormal intracellular level (amount) of calcium, compared to controls.
WB:WBPaper00041673
WB:WBPerson2987
Cells exhibit a higher level of calcium in the cytosol, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002617
cytosolic calcium levels increased
Cells exhibit a higher level of calcium in the cytosol, compared to controls.
WB:WBPaper00041673
WB:WBPerson2987
Cells exhibit a lower level of calcium in the cytosol, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002618
cytosolic calcium levels decreased
Cells exhibit a lower level of calcium in the cytosol, compared to controls.
WB:WBPaper00041673
WB:WBPerson2987
Animals exhibit increased occurrence of cell death, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002619
cell death increased
Animals exhibit increased occurrence of cell death, compared to controls.
WB:WBPaper00041673
WB:WBPerson2987
Animals exhibit decreased occurrence of cell death, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002620
cell death decreased
Animals exhibit decreased occurrence of cell death, compared to controls.
WB:WBPaper00041673
WB:WBPerson2987
Animals exhibit a decrease in the expression of one or more known, endogenous, antimicrobial genes, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002621
antimicrobial gene expression reduced
Animals exhibit a decrease in the expression of one or more known, endogenous, antimicrobial genes, compared to controls.
WB:WBPaper00053771
WB:WBPerson2987
Animals exhibit decreased recruitment of actin to a site of injury, compared to controls.
decreased recruitment of actin upon injury
C_elegans_phenotype_ontology
WBPhenotype:0002622
decreased recruitment of actin upon wounding
Animals exhibit decreased recruitment of actin to a site of injury, compared to controls.
WB:WBPaper00059214
WB:WBPerson2987
WB:WBPerson499
Animals exhibit no induction of expression of an antimicrobial peptide after an injury, unlike control animals.
no induction of antimicrobial peptide expression after wounding
C_elegans_phenotype_ontology
WBPhenotype:0002623
no induction of antimicrobial peptide expression after injury
Animals exhibit no induction of expression of an antimicrobial peptide after an injury, unlike control animals.
WB:WBPaper00059214
WB:WBPerson2987
WB:WBPerson499
Cells display reduced incorporation of the thymidine analogue 5-Ethynyl-2'-deoxyuridine (EdU), suggesting reduced cell proliferation. Incorporation of EdU is an indication of active DNA synthesis and thus an indication of cells proceeding through the cell cycle.
C_elegans_phenotype_ontology
WBPhenotype:0002624
EdU incorporation reduced
Cells display reduced incorporation of the thymidine analogue 5-Ethynyl-2'-deoxyuridine (EdU), suggesting reduced cell proliferation. Incorporation of EdU is an indication of active DNA synthesis and thus an indication of cells proceeding through the cell cycle.
PMID:32973031
WB:WBPerson2987
WB:WBPerson36183
Animals exhibit visible, structural degeneration of the head, unlike control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002625
head degeneration
Animals exhibit visible, structural degeneration of the head, unlike control animals.
WB:WBPerson2987
WB:WBPerson36183
PMID:32973031
Animals exhibit an abnormal attachment (or lack thereof) to a substrate, compared to controls. For some parasitic worms, attachment to host tissue surfaces, like endothelium, is a necessary behavior for their life cycle.
C_elegans_phenotype_ontology
WBPhenotype:0002626
attachment to substrate abnormal
Animals exhibit an abnormal attachment (or lack thereof) to a substrate, compared to controls. For some parasitic worms, attachment to host tissue surfaces, like endothelium, is a necessary behavior for their life cycle.
PMID:32973031
WB:WBPerson2987
WB:WBPerson36183
Animals exhibit an abnormal attachment (or lack thereof) to a substrate in vitro, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002627
in vitro attachment to substrate abnormal
Animals exhibit an abnormal attachment (or lack thereof) to a substrate in vitro, compared to controls.
PMID:32973031
WB:WBPerson2987
WB:WBPerson36183
Animals exhibit a reduced attachment to a substrate in vitro, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002628
in vitro attachment to substrate reduced
Animals exhibit a reduced attachment to a substrate in vitro, compared to controls.
PMID:32973031
WB:WBPerson2987
WB:WBPerson36183
Animals exhibit edema (swelling) of the intestine, compared to control animals. This swelling is distinct from distension of the intestinal lumen (swollen intestinal lumen).
intestinal oedema
swollen intestine
C_elegans_phenotype_ontology
WBPhenotype:0002629
intestinal edema
Animals exhibit edema (swelling) of the intestine, compared to control animals. This swelling is distinct from distension of the intestinal lumen (swollen intestinal lumen).
PMID:32973031
WB:WBPerson2987
WB:WBPerson36183
Animals exhibit degeneration of the epithelial system (skin, integument or tegument), compared to control animals.
integument degeneration
tegument degeneration
C_elegans_phenotype_ontology
WBPhenotype:0002630
epithelial system degeneration
Animals exhibit degeneration of the epithelial system (skin, integument or tegument), compared to control animals.
PMID:32973031
WB:WBPerson2987
WB:WBPerson36183
Animals exhibit edema (swelling) of one or more tissues, compared to control animals.
tissue oedema
tissue swelling
C_elegans_phenotype_ontology
WBPhenotype:0002631
tissue edema
Animals exhibit edema (swelling) of one or more tissues, compared to control animals.
PMID:32973031
WB:WBPerson2987
WB:WBPerson36183
Animals exhibit cells with an abnormal degree of chromatin accessibility, compared to controls, detected using techniques such as ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing).
chromatin accessibility phenotype
chromatin accessibility variant
C_elegans_phenotype_ontology
WBPhenotype:0002632
chromatin accessibility abnormal
Animals exhibit cells with an abnormal degree of chromatin accessibility, compared to controls, detected using techniques such as ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing).
WB:WBPaper00061371
WB:WBPerson2987
WB:WBPerson712
Animals exhibit a pharynx that recedes into the animal's interior such that the animal cannot feed.
Pin
C_elegans_phenotype_ontology
WBPhenotype:0002633
pharynx ingressed
Animals exhibit a pharynx that recedes into the animal's interior such that the animal cannot feed.
WB:WBPaper00055692
WB:WBPerson2987
WB:WBPerson43879
Animals exhibit a resistance to endoplasmic reticulum (ER) stressors such as an accumulation of unfolded proteins or the presence of chemicals that induce ER stress, such as dithiothreitol (DDT) or tunicamycin, compared to controls. This may mean that animals fare better than controls in terms of survival or some metric of health when exposed to an inducer of ER stress.
C_elegans_phenotype_ontology
WBPhenotype:0002634
ER stress resistant
Animals exhibit a resistance to endoplasmic reticulum (ER) stressors such as an accumulation of unfolded proteins or the presence of chemicals that induce ER stress, such as dithiothreitol (DDT) or tunicamycin, compared to controls. This may mean that animals fare better than controls in terms of survival or some metric of health when exposed to an inducer of ER stress.
WB:WBPaper00050013
WB:WBPerson2987
Animals shed fragments of epidermis into the surrounding environment, unlike controls. In embryos, these fragments can be seen in the extra-embryonic space.
C_elegans_phenotype_ontology
WBPhenotype:0002635
epidermal shedding
Animals shed fragments of epidermis into the surrounding environment, unlike controls. In embryos, these fragments can be seen in the extra-embryonic space.
WB:WBPaper00052963
WB:WBPerson2987
One or more cells of the animal exhibit chromatin that has become detached from the nuclear periphery, unlike controls.
C_elegans_phenotype_ontology
WBPhenotype:0002636
detachment of chromatin from nuclear periphery
One or more cells of the animal exhibit chromatin that has become detached from the nuclear periphery, unlike controls.
WB:WBPaper00048885
WB:WBPerson14737
WB:WBPerson2987
Animals (or cells of the animal) exhibit reduced levels of iron in the body (or cells) compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002637
iron levels decreased
Animals (or cells of the animal) exhibit reduced levels of iron in the body (or cells) compared to controls.
WB:WBPaper00055104
WB:WBPerson2987
WB:WBPerson35689
Animals are more prone to infection, sickness and/or death caused by oomycete pathogens compared to control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002638
increased susceptibility to oomycete infection
Animals are more prone to infection, sickness and/or death caused by oomycete pathogens compared to control animals.
WB:WBPaper00060871
WB:WBPerson2987
WB:WBPerson53483
Animals exhibit specific or general variations in the composition of the microbiome at a body site compared to controls.
microbiome composition variant
C_elegans_phenotype_ontology
WBPhenotype:0002639
microbiome composition abnormal
Animals exhibit specific or general variations in the composition of the microbiome at a body site compared to controls.
WB:WBPerson10314
WB:WBPerson2987
The physical strength or integrity of the cuticle is decreased compared to that observed for control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002640
cuticle integrity decreased
The physical strength or integrity of the cuticle is decreased compared to that observed for control animals.
WB:WBPaper00061220
WB:WBPerson2987
The cuticle of animals becomes more permeable to dyes or stains, such as Hoechst 33258, or other substances compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002641
cuticle permeability increased
The cuticle of animals becomes more permeable to dyes or stains, such as Hoechst 33258, or other substances compared to controls.
WB:WBPaper00061220
WB:WBPerson2987
WB:WBPerson3900
Animals exposed to an exogenous chemical exhibit an abnormal accumulation of this chemical in the body of the animals, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002642
chemical accumulation abnormal
Animals exposed to an exogenous chemical exhibit an abnormal accumulation of this chemical in the body of the animals, compared to controls.
WB:WBPaper00061220
WB:WBPerson2987
WB:WBPerson3900
Animals exposed to an exogenous chemical exhibit an abnormal increase in accumulation of this chemical in the body of the animals, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002643
chemical accumulation increased
Animals exposed to an exogenous chemical exhibit an abnormal increase in accumulation of this chemical in the body of the animals, compared to controls.
WB:WBPaper00061220
WB:WBPerson2987
WB:WBPerson3900
Animals do not respond to the edge or gap in the medium surface they were supported on in the same manner as controls. In Mitchell et al., the precipice response was defined to be that within 2 seconds of the nose moving off the edge of the agar chunk, the worm begins a reversal that completes at least one full sine wave.
precipice response abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002644
precipice response variant
Animals do not respond to the edge or gap in the medium surface they were supported on in the same manner as controls. In Mitchell et al., the precipice response was defined to be that within 2 seconds of the nose moving off the edge of the agar chunk, the worm begins a reversal that completes at least one full sine wave.
WB:WBPaper00061677
WB:WBPerson2987
WB:WBPerson712
Animals exhibit an abnormal recovery from heat stress, compared to controls.
heat stress recovery abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002645
Exposure of wild type worms to a 6 h heat shock at 33°C led to a 20% decrease in worms with normal movement after a 48 h recovery at 20°C.
thermorecovery abnormal
Animals exhibit an abnormal recovery from heat stress, compared to controls.
WB:WBPaper00060029
WB:WBPerson14884
WB:WBPerson2987
Exposure of wild type worms to a 6 h heat shock at 33°C led to a 20% decrease in worms with normal movement after a 48 h recovery at 20°C.
WB:WBPaper00060029
Animals exhibit reduced recovery from heat stress compared to controls. Reduced recovery may be indicated, for example, by a decrease in normal movement, such as uncoordinated or jerky movement or paralysis, compared to controls.
heat stress recovery reduced
C_elegans_phenotype_ontology
WBPhenotype:0002646
thermorecovery reduced
Animals exhibit reduced recovery from heat stress compared to controls. Reduced recovery may be indicated, for example, by a decrease in normal movement, such as uncoordinated or jerky movement or paralysis, compared to controls.
WB:WBPaper00060029
WB:WBPerson14884
WB:WBPerson2987
Animals display variations in the structure, organization of components, or spatial pattern of the neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002647
dendrite morphology variant
Animals display variations in the structure, organization of components, or spatial pattern of the neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals.
WB:WBPaper00043988
WB:WBPerson2987
WB:WBPerson557
Animals display variations in the number or pattern of neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals.
C_elegans_phenotype_ontology
WBPhenotype:0002648
dendrite branching variant
Animals display variations in the number or pattern of neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals.
WB:WBPaper00043988
WB:WBPerson2987
WB:WBPerson557
Characteristic response to chemicals with respect to egg-laying behavior varies compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002649
egg laying response to chemical abnormal
Characteristic response to chemicals with respect to egg-laying behavior varies compared to control.
WB:WBPaper00060230
WB:WBPerson2987
WB:WBPerson712
Characteristic response to extracted lipopolysaccharide from pathogens with respect to egg-laying behavior varies compared to control conditions.
C_elegans_phenotype_ontology
WBPhenotype:0002650
egg laying response to pathogen lipopolysaccharide variant
Characteristic response to extracted lipopolysaccharide from pathogens with respect to egg-laying behavior varies compared to control conditions.
WB:WBPaper00060230
WB:WBPerson2987
WB:WBPerson712
Cells exhibit an abnormal production of exophers, large (approximately four microns in diameter) membrane-bound extracellular vesicles that are released by budding out of cells into the extracellular space, compared to controls.
exopher production abnormal
exopher-genesis abnormal
exopher-genesis phenotype
C_elegans_phenotype_ontology
WBPhenotype:0002651
exopher production phenotype
Cells exhibit an abnormal production of exophers, large (approximately four microns in diameter) membrane-bound extracellular vesicles that are released by budding out of cells into the extracellular space, compared to controls.
WB:WBPaper00061698
WB:WBPerson23531
WB:WBPerson2987
Cells exhibit a increase in production of exophers compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002652
exopher production increased
Cells exhibit a increase in production of exophers compared to controls.
WB:WBPaper00061698
WB:WBPerson23531
WB:WBPerson2987
Cells exhibit a decrease in production of exophers compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002653
exopher production decreased
Cells exhibit a decrease in production of exophers compared to controls.
WB:WBPaper00061698
WB:WBPerson23531
WB:WBPerson2987
Muscle cells exhibit an abnormal production of exophers compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002654
exopher production in muscle phenotype
Muscle cells exhibit an abnormal production of exophers compared to controls.
WB:WBPaper00061698
WB:WBPerson23531
WB:WBPerson2987
Muscle cells exhibit a decrease in production of exophers compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002655
exopher production in muscle decreased
Muscle cells exhibit a decrease in production of exophers compared to controls.
WB:WBPaper00061698
WB:WBPerson23531
WB:WBPerson2987
Muscle cells exhibit an increase in production of exophers compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002656
exopher production in muscle increased
Muscle cells exhibit an increase in production of exophers compared to controls.
WB:WBPaper00061698
WB:WBPerson23531
WB:WBPerson2987
Animals exhibit intolerance (e.g. lethality or significant growth defect) when exposed to saturated fatty acids via the diet, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002657
dietary saturated fatty acid intolerant
Animals exhibit intolerance (e.g. lethality or significant growth defect) when exposed to saturated fatty acids via the diet, compared to controls.
WB:WBPaper00060877
WB:WBPerson2987
WB:WBPerson488
Animals exhibit variations in muscle strength, as measured by a strength determining assay, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002658
muscle strength phenotype
Animals exhibit variations in muscle strength, as measured by a strength determining assay, compared to controls.
WB:WBPaper00061159
WB:WBPerson1754
WB:WBPerson2987
Animals exhibit a decrease in muscle strength, as measured by a strength determining assay, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002659
muscle strength decreased
Animals exhibit a decrease in muscle strength, as measured by a strength determining assay, compared to controls.
WB:WBPaper00061159
WB:WBPerson1754
WB:WBPerson2987
Animals exhibit a depletion of germline stem cells, compared to controls.
C_elegans_phenotype_ontology
WBPhenotype:0002660
germline stem cell depletion
Animals exhibit a depletion of germline stem cells, compared to controls.
WB:WBPaper00044909
WB:WBPerson2987
WB:WBPerson5747
Genes, whose expression is typically induced by an innate immune response, are actively expressed under conditions which would not normally induce an innate immune response gene expression program.
C_elegans_phenotype_ontology
WBPhenotype:0002661
constitutive expression of innate immune response genes
Genes, whose expression is typically induced by an innate immune response, are actively expressed under conditions which would not normally induce an innate immune response gene expression program.
WB:WBPaper00064532
WB:WBPerson2987
WB:WBPerson38719
Animals exhibit an increase in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002662
transgene silencing increased
Animals exhibit an increase in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control.
WB:WBPaper00064532
WB:WBPerson2987
WB:WBPerson38719
Cells of the animal exhibit variations in the intracellular lipid surveillance response, responsible for responding to and addressing lipid depletion inside of cells, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002663
intracellular lipid surveillance response abnormal
Cells of the animal exhibit variations in the intracellular lipid surveillance response, responsible for responding to and addressing lipid depletion inside of cells, compared to control.
WB:WBPaper00064071
WB:WBPerson2987
WB:WBPerson58409
Any variation in the placement of RNA within in a cell or cellular compartment compared to control.
RNA localization abnormal
RNA subcellular localization abnormal
C_elegans_phenotype_ontology
WBPhenotype:0002664
RNA subcellular localization variant
Any variation in the placement of RNA within in a cell or cellular compartment compared to control.
WB:WBPerson2987
Any variation in the properties of an RNA condensate within a cell or cellular compartment compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002665
RNA condensate variant
Any variation in the properties of an RNA condensate within a cell or cellular compartment compared to control.
WB:WBPaper00065975
WB:WBPerson10419
WB:WBPerson2987
An abnormal dissolution of an RNA condensate within a cell or cellular compartment compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0002666
abnormal dissolution of RNA condensate
An abnormal dissolution of an RNA condensate within a cell or cellular compartment compared to control.
WB:WBPaper00065975
WB:WBPerson10419
WB:WBPerson2987
Any variation in the specific actions or reactions of a hermaphrodite during mating compared to control.
hermaphrodite mating abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004001
hermaphrodite mating variant
Any variation in the specific actions or reactions of a hermaphrodite during mating compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit defects in the production of the sensory signal to attract males.
C_elegans_phenotype_ontology
WBPhenotype:0004002
attraction signal defective
Animals exhibit defects in the production of the sensory signal to attract males.
WB:WBPaper00005109
WB:WBPerson557
Males exhibit defects in their response to the mate-finding cue.
mate finding abnormal
C_elegans_phenotype_ontology
response to male attractant abnormal
WBPhenotype:0004003
mate finding defective
Males exhibit defects in their response to the mate-finding cue.
WB:WBPaper00005109
WB:WBPerson557
The inability of a male to respond properly to a potential mate after contact. In C.elegans, proper response includes apposing the ventral side of his tail to the hermaphrodite's body and swimming backward.
C_elegans_phenotype_ontology
WBPhenotype:0004004
male response to contact defective
The inability of a male to respond properly to a potential mate after contact. In C.elegans, proper response includes apposing the ventral side of his tail to the hermaphrodite's body and swimming backward.
GO:0034606
WB:WBPaper00000392
WB:WBPaper00002109
WB:WBPerson557
Males exhibit variations in mating behavior prior to contacting its mate compared to control.
pre hermaphrodite contact abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004005
pre hermaphrodite contact variant
Males exhibit variations in mating behavior prior to contacting its mate compared to control.
WB:WBPerson557
Males exhibit variations in mating behavior after contacting its mate compared to control.
post hermaphrodite contact abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004006
post hermaphrodite contact variant
Males exhibit variations in mating behavior after contacting its mate compared to control.
WB:WBPerson557
Males exhibit defects in the continuous prodding of spicule tips at the vulva prior to prolonged spicule insertion.
C_elegans_phenotype_ontology
spicule prodding defective
WBPhenotype:0004007
periodic spicule prodding defective
Males exhibit defects in the continuous prodding of spicule tips at the vulva prior to prolonged spicule insertion.
GO:0034609
WB:WBPerson2021
WB:WBPerson557
Males exhibit defects in the prolonged, tonic, spicule extrusion through the vulva prior to sperm transfer.
C_elegans_phenotype_ontology
prolonged spicule protraction defective
WBPhenotype:0004008
sustained spicule protraction defective
Males exhibit defects in the prolonged, tonic, spicule extrusion through the vulva prior to sperm transfer.
GO:0034609
WB:WBPerson2021
WB:WBPerson557
Any variation in the mating process that includes the male stopping at the vulva (usually after backing) compared to control. In C. elegans general vulva location (stopping) requires the hook sensillum.
approximate vulval location abnormal
C_elegans_phenotype_ontology
approximate vulva location variant
general vulval location abnormal
WBPhenotype:0004009
approximate vulval location variant
Any variation in the mating process that includes the male stopping at the vulva (usually after backing) compared to control. In C. elegans general vulva location (stopping) requires the hook sensillum.
WB:WBPaper00002109
WB:WBPerson2021
WB:WBPerson557
Any variation in the mating process that includes the male positioning his tail precisely over the vulva so that he may insert his spicules and ejaculate compared to control. In C. elegans precise vulva location (coordinating movement and tail positioning) requires the post cloacal sensillium and the spicules.
precise vulval location abnormal
C_elegans_phenotype_ontology
precise vulva location variant
WBPhenotype:0004010
precise vulval location variant
Any variation in the mating process that includes the male positioning his tail precisely over the vulva so that he may insert his spicules and ejaculate compared to control. In C. elegans precise vulva location (coordinating movement and tail positioning) requires the post cloacal sensillium and the spicules.
WB:WBPaper00002109
WB:WBPerson2021
WB:WBPerson557
Any variation in the retraction of spicules after all sperm that exit the seminal vesicle have been released compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0004011
sperm transfer cessation defective
Any variation in the retraction of spicules after all sperm that exit the seminal vesicle have been released compared to control.
WB:WBPaper00028400
Any variation in the continued movement of sperm through the vas deferens, exiting the cloaca, compared to control. In C. elegans, when all sperm that exit the seminal vesicle have been released, the spicules retract into the male.
C_elegans_phenotype_ontology
WBPhenotype:0004012
sperm transfer continuation defective
Any variation in the continued movement of sperm through the vas deferens, exiting the cloaca, compared to control. In C. elegans, when all sperm that exit the seminal vesicle have been released, the spicules retract into the male.
WB:WBPaper00028400
Any variation in the initial movement of sperm through the vas deferens, exiting the cloaca, compared to control.
C_elegans_phenotype_ontology
WBPhenotype:0004013
sperm release defective
Any variation in the initial movement of sperm through the vas deferens, exiting the cloaca, compared to control.
WB:WBPaper00028400
Any variation in the specific actions or reactions of a hermaphrodite after male contact during mating compared to control.
post male contact abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004014
post male contact variant
Any variation in the specific actions or reactions of a hermaphrodite after male contact during mating compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the specific actions or reactions of a hermaphrodite prior to male contact during mating compared to control.
pre male contact abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004015
pre male contact variant
Any variation in the specific actions or reactions of a hermaphrodite prior to male contact during mating compared to control.
WB:WBPerson2021
WB:WBPerson557
Any variation in the behavior exhibited by dauer larva in which they crawl up upon the substrate and wave back and forth while standing on their tail compared to control. Nictation is often associated with the search for a new host.
dauer nictation behavior abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004016
dauer nictation behavior variant
Any variation in the behavior exhibited by dauer larva in which they crawl up upon the substrate and wave back and forth while standing on their tail compared to control. Nictation is often associated with the search for a new host.
WB:WBPaper00027241
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in their ability to maintain characteristic and effective locomotion compared to control.
locomotor coordination abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004017
locomotor coordination variant
Animals exhibit variations in their ability to maintain characteristic and effective locomotion compared to control.
WB:WBperson557
Any variation in the propagation of the contraction sine wave along the body while an animal travels from one location to another, compared to control.
sinusoidal movement abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004018
sinusoidal movement variant
Any variation in the propagation of the contraction sine wave along the body while an animal travels from one location to another, compared to control.
WB:WBPerson2021
WB:WBPerson557
OBSOLETE.
C_elegans_phenotype_ontology
WBPhenotype:0004021
obsolete exaggerated body bends
true
Any variation in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control.
amplitude of body bends variant
amplitude of movement abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004022
amplitude of sinusoidal movement variant
Any variation in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the frequency of oscillations between adjacent body segments from that observed for control animals.
WBPhenotype:0002329
frequency of sinusoidal movement variant
temporal frequency of sinusoidal movement variant
bending frequency abnormal
frequency of body bend abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004023
frequency of body bend variant
Animals exhibit variations in the frequency of oscillations between adjacent body segments from that observed for control animals.
WB:WBPaper00024949
WB:WBPerson557
WB:WBPerson712
Any variation in the distance in the line of advance of a body wave from any one point to the next point of corresponding phase compared to control.
wavelength of movement abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004024
wavelength of movement variant
Any variation in the distance in the line of advance of a body wave from any one point to the next point of corresponding phase compared to control.
WB:WBPerson2021
WB:WBPerson557
Animals exhibit variations in the net velocity of an animal, that is, the maximum distance an animal traverses over an extended period of time, from that observed for control animals.
velocity of movement abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004025
velocity of movement variant
Animals exhibit variations in the net velocity of an animal, that is, the maximum distance an animal traverses over an extended period of time, from that observed for control animals.
WB:WBPaper00032008
WB:WBPerson712
Variations in the ability of an animal to respond with characteristic backward movement after a nose-on collision with an object compared to control. In C. elegans, this phenotype is usually assayed via stroking with a hair or similar fiber on the anterior most tip of the animal.
nose touch abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004026
nose touch variant
Variations in the ability of an animal to respond with characteristic backward movement after a nose-on collision with an object compared to control. In C. elegans, this phenotype is usually assayed via stroking with a hair or similar fiber on the anterior most tip of the animal.
WB:WBPaper00001705
WB:WBPerson557
Animals exhibit variations in their response to substrate vibration compared to control.
plate tap reflex abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004027
plate tap reflex variant
Animals exhibit variations in their response to substrate vibration compared to control.
WB:WBPerson557
Animals exhibit variations in modulating their locomotory rate in response to its food , compared to control. Basal slowing response refers to when well-fed animals move more slowly in the presence of bacteria than in the absence of bacteria . Second , food-deprived control animals , when transferred to bacteria , display a dramatically enhanced slowing response that ensures that the animals do not leave their newly encountered source of food.
slowing response on food abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004028
slowing response on food variant
Animals exhibit variations in modulating their locomotory rate in response to its food , compared to control. Basal slowing response refers to when well-fed animals move more slowly in the presence of bacteria than in the absence of bacteria . Second , food-deprived control animals , when transferred to bacteria , display a dramatically enhanced slowing response that ensures that the animals do not leave their newly encountered source of food.
WB:WBPaper00004195
WB:WBPerson2021
Any variation with respect to perception or response to mechanical stimuli in a sex dependent manner compared to control animals.
sexually dimorphic mechanosensation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004029
sexually dimorphic mechanosensation variant
Any variation with respect to perception or response to mechanical stimuli in a sex dependent manner compared to control animals.
WB:WBPerson2021
WB:WBPerson557
Any variation in the response by the male to a hermaphrodite after initial contact following mate finding compared to control. In C. elegans the male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.
Rsp
male response to hermaphrodite abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004030
male response to hermaphrodite variant
Any variation in the response by the male to a hermaphrodite after initial contact following mate finding compared to control. In C. elegans the male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.
GO:0034606
WB:WBPaper00002109
WB:WBPerson2021
WB:WBPerson557
Any variation in the ability of an animal to search for a mate compared to control. In C. elegans, this is defined by failure of the leaving assay.
mate searching abnormal
C_elegans_phenotype_ontology
WBPhenotype:0004031
mate searching variant
Any variation in the ability of an animal to search for a mate compared to control. In C. elegans, this is defined by failure of the leaving assay.
WB:WBPaper00024428
The apparent partial collapse of the vulval invagination and the elongation of central vulva cells often leading to a flattened appearance.
Sqv
C_elegans_phenotype_ontology
WBPhenotype:0006001
squashed vulva
The apparent partial collapse of the vulval invagination and the elongation of central vulva cells often leading to a flattened appearance.
WB:WBPaper00003405
Any variation in the processes that govern acquisition of particular cell fates in the embryo, from the time of zygote formation until hatching compared to control.
embryonic cell fate specification abnormal
C_elegans_phenotype_ontology
WBPhenotype:0008001
embryonic cell fate specification variant
Any variation in the processes that govern acquisition of particular cell fates in the embryo, from the time of zygote formation until hatching compared to control.
WB:kmva
Any variation in the processes that govern acquisition of somatic cell fates in the embryo, from the time of zygote formation until hatching compared to control.
embryonic somatic cell fate specification abnormal
C_elegans_phenotype_ontology
WBPhenotype:0008002
embryonic somatic cell fate specification variant
Any variation in the processes that govern acquisition of somatic cell fates in the embryo, from the time of zygote formation until hatching compared to control.
WB:kmva
Any variation in a learned olfactory response whereby exposure of animals to odorants during specific developmental times or physiological states results in a lasting memory compared to control. In control animals, this imprinting determines the animal's behavior upon encountering the same odorant at a later time.
olfactory imprinting abnormal
odorant imprinting abnormal
C_elegans_phenotype_ontology
WBPhenotype:0008003
odorant imprinting variant
Any variation in a learned olfactory response whereby exposure of animals to odorants during specific developmental times or physiological states results in a lasting memory compared to control. In control animals, this imprinting determines the animal's behavior upon encountering the same odorant at a later time.
WB:WBPaper00026662
WB:WBPerson1843
Variations in the process(es) by which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter compared to control.
cell growth abnormal
C_elegans_phenotype_ontology
WBPhenotype:0010001
cell growth variant
Variations in the process(es) by which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter compared to control.
GO:0016049
WB:rk
Variations in the process(es) involved in the assembly and arrangement of cell structures compared to control.
cell organization biogenesis abnormal
C_elegans_phenotype_ontology
WBPhenotype:0010002
cell organization biogenesis variant
Variations in the process(es) involved in the assembly and arrangement of cell structures compared to control.
GO:0016043
WB:rk
Animals exhibit a decreased rate programmed cell death pathway leading to the destruction of the cell, viewable in its terminally dismanteled form of a cell corpse, compared to that observed for control cells.
C_elegans_phenotype_ontology
WBPhenotype:0010003
cell corpse appearance delayed
Animals exhibit a decreased rate programmed cell death pathway leading to the destruction of the cell, viewable in its terminally dismanteled form of a cell corpse, compared to that observed for control cells.
WB:WBPerson712
WB:rk
Variations in the process(es) that constitute cell corpse degradation within the engulfing cell compared to control.
WB:rk
cell corpse degradation abnormal
C_elegans_phenotype_ontology
WBPhenotype:0010004
cell corpse degradation variant
Variations in the process(es) that constitute cell corpse degradation within the engulfing cell compared to control.
WB:rk