AmiGO 2: Term Details for "sodium:proton antiporter activity" (GO:0015385)

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Term Information

Accession: GO:0015385
Name: sodium:proton antiporter activity
Ontology: molecular_function
Synonyms: sodium/hydrogen antiporter activity, sodium:hydrogen antiporter activity, sodium:hydrogen exchange activity, sodium:hydrogen exchanger, pH-dependent sodium:hydrogen antiporter activity, pH-dependent sodium:proton antiporter activity
Alternate IDs: GO:0015502
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). Source: TC:2.A.35.1.1, TC:2.A.36.-.-
Comment: None
History: See term history for GO:0015385 at QuickGO
Chem. react.: has participant hydron
Subset: None
Related: Link to all genes and gene products annotated to sodium:proton antiporter activity (excluding "regulates").; Link to all direct and indirect annotations to sodium:proton antiporter activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for sodium:proton antiporter activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0003674 molecular_function
GO:0009987 cellular process
GO:0055085 transmembrane transport
GO:0006810 transport
GO:0005215 transporter activity
GO:0022804 active transmembrane transporter activity
GO:0034220 monoatomic ion transmembrane transport
GO:0006811 monoatomic ion transport
GO:0022857 transmembrane transporter activity
GO:0098662 inorganic cation transmembrane transport
GO:0098660 inorganic ion transmembrane transport
GO:0015318 inorganic molecular entity transmembrane transporter activity
GO:0030001 metal ion transport
GO:0098655 monoatomic cation transmembrane transport
GO:0006812 monoatomic cation transport
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0015291 secondary active transmembrane transporter activity
GO:0022853 active monoatomic ion transmembrane transporter activity
GO:0015297 antiporter activity
GO:0022890 inorganic cation transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
GO:0008324 monoatomic cation transmembrane transporter activity
GO:1902600 proton transmembrane transport
GO:0006814 sodium ion transport
GO:0140828 metal cation:monoatomic cation antiporter activity
GO:0015078 proton transmembrane transporter activity
GO:0035725 sodium ion transmembrane transport
GO:0051139 metal cation:proton antiporter activity
GO:0015081 sodium ion transmembrane transporter activity
GO:0015385 sodium:proton antiporter activity
GO:0140831 L-asparagine, sodium:proton antiporter activity
GO:0140830 L-glutamine, sodium:proton antiporter activity
GO:0140832 L-histidine, sodium:proton antiporter activity
GO:0032416 negative regulation of sodium:proton antiporter activity
GO:0140893 neutral amino acid, sodium:proton antiporter activity
GO:0032417 positive regulation of sodium:proton antiporter activity
GO:0032415 regulation of sodium:proton antiporter activity
GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential

Parents of sodium:proton antiporter activity (GO:0015385)

subject	relation	object
sodium:proton antiporter activity	RO:0004009	sodium(1+) (CHEBI:29101)
sodium:proton antiporter activity	RO:0000057	hydron (CHEBI:15378)
sodium:proton antiporter activity	is_a	sodium ion transmembrane transporter activity (GO:0015081)
sodium:proton antiporter activity	is_a	metal cation:proton antiporter activity (GO:0051139)

Children of sodium:proton antiporter activity (GO:0015385)

subject	relation	object
negative regulation of sodium:proton antiporter activity (GO:0032416)	RO:0002212	sodium:proton antiporter activity
L-histidine, sodium:proton antiporter activity (GO:0140832)	is_a	sodium:proton antiporter activity
neutral amino acid, sodium:proton antiporter activity (GO:0140893)	is_a	sodium:proton antiporter activity
regulation of sodium:proton antiporter activity (GO:0032415)	RO:0002211	sodium:proton antiporter activity
L-asparagine, sodium:proton antiporter activity (GO:0140831)	is_a	sodium:proton antiporter activity
sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential (GO:0086040)	is_a	sodium:proton antiporter activity
L-glutamine, sodium:proton antiporter activity (GO:0140830)	is_a	sodium:proton antiporter activity
positive regulation of sodium:proton antiporter activity (GO:0032417)	RO:0002213	sodium:proton antiporter activity

MetaCyc: TRANS-RXN-129
Reactome: R-HSA-2872463; R-HSA-2872444; R-HSA-5661086; R-HSA-2889070; R-HSA-425983; R-HSA-425994; R-HSA-426015; R-HSA-425965; R-HSA-5661039
RHEA: 29251