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Protein Ontology report - bone morphogenetic protein receptor type-1B (human)
PR:O00238 - http://purl.obolibrary.org/obo/PR_O00238
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:O00238   
  PRO namebone morphogenetic protein receptor type-1B (human) 
  Synonyms
PRO-Short-label: EXACT:hBMPR1B
Gene-based: RELATED:BMPR1B
Other: EXACT:BMP type-1B receptor (human) | BMPR-1B (human) | CDw293 (human)
  Definition"A BMP receptor type-1B that is encoded in the genome of human." [PRO:CNA, UniProtKB:O00238] 
  PRO Categoryorganism-gene 
  ParentPR:000000036 BMP receptor type-1B
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1077 BMPR1B (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O00238
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:O00238 bone morphogenetic protein receptor type-1B (human), hBMPR1B

organism-sequence


PR:000000146 BMP receptor type-1B sequence variant I200K (human), hBMPR1B/var:I200K
Yes
organism-sequence


PR:000000147 BMP receptor type-1B sequence variant R486W (human), hBMPR1B/var:R486W
Yes
organism-sequence


PR:O00238-1 bone morphogenetic protein receptor type-1B isoform 1 (human), hBMPR1B/iso:1
Yes
organism-modification


PR:000036426 BMP receptor type-1B isoform 1 phosphorylated 1 (human), hBMPR1B/iso:1/Phos:1
Yes
organism-sequence


PR:O00238-2 bone morphogenetic protein receptor type-1B isoform h2 (human), hBMPR1B/iso:h2

organism-modification


PR:000046495 bone morphogenetic protein receptor type-1B, signal peptide removed form (human), hBMPR1B/SigPep-

organism-modification


PR:000046496 bone morphogenetic protein receptor type-1B, signal peptide removed phosphoserine form (human), hBMPR1B/SigPep-/PhosSer+

organism-modification


PR:000046496 bone morphogenetic protein receptor type-1B, signal peptide removed phosphoserine form (human), hBMPR1B/SigPep-/PhosSer+

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000146 hBMPR1B/var:I200K
UniProtKB:O00238, Ile-200, CHEBI:29967 | UniProtKB:O00238-1, Ile-200, CHEBI:29967 | BMP receptor type-1B sequence variant 1 (human)
"A bone morphogenetic protein receptor type-1B (human) that has a Lys residue at the position equivalent to Ile-200 of the amino acid sequence represented by UniProtKB:O00238-1. Example: UniProtKB:O00238-1, Ile-200, CHEBI:29967." [PMID:14523231, PRO:CNA, PRO:DAN]		 associated_with_disease_progressionDO:0050581 brachydactyly PMID:14523231
enablesNOT GO:0004674 protein serine/threonine kinase activity PMID:14523231
located_inGO:0009986 cell surface PMID:14523231
PR:000000147 hBMPR1B/var:R486W
UniProtKB:O00238, Arg-486, CHEBI:29954 | UniProtKB:O00238-1, Arg-486, CHEBI:29954 | BMP receptor type-1B sequence variant 2 (human)
"A bone morphogenetic protein receptor type-1B (human) that has a Trp residue at the position equivalent to Arg-486 of the amino acid sequence represented by UniProtKB:O00238-1. Example: UniProtKB:O00238-1, Arg-486, CHEBI:29954." [PMID:14523231, PRO:CNA, PRO:DAN]		 associated_with_disease_progressionDO:0050581 brachydactyly PMID:14523231
enablesGO:0004674 protein serine/threonine kinase activity PMID:14523231
located_inGO:0009986 cell surface PMID:14523231
PR:000036426 hBMPR1B/iso:1/Phos:1

"A BMP receptor type-1B isoform 1 phosphorylated 1 in human." [PMID:10051328, PMID:14523231, PRO:CNA]		 acts_upstream_of_or_withinGO:0030509 BMP signaling pathway PMID:10051328
GO:0045597 positive regulation of cell differentiation PMID:14523231
PR:O00238-1 hBMPR1B/iso:1

"A BMP receptor type-1B isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0030509 BMP signaling pathway PMID:10051328