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Protein Ontology report - interleukin-1 receptor antagonist protein (human)
PR:P18510 - http://purl.obolibrary.org/obo/PR_P18510
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P18510   
  PRO nameinterleukin-1 receptor antagonist protein (human) 
  Synonyms
PRO-Short-label: EXACT:hIL1RN
Gene-based: RELATED:IL1F3 | IL1RA | IL1RN
Other: EXACT:anakinra (human) | ICIL-1RA (human) | IL-1ra (human) | IL-1RN (human) | IL1 inhibitor (human)
  Definition"An interleukin-1 receptor antagonist protein that is encoded in the genome of human." [PRO:CNA, UniProtKB:P18510] 
  PRO Categoryorganism-gene 
  ParentPR:000001137 interleukin-1 receptor antagonist protein
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6000 IL1RN (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P18510
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P18510 interleukin-1 receptor antagonist protein (human), hIL1RN

organism-sequence


PR:P18510-1 interleukin-1 receptor antagonist protein isoform 1 (human), hIL1RN/iso:1

organism-modification


PR:000036601 interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form (human), hIL1RN/iso:1/SigPep-
Yes
organism-sequence


PR:P18510-2 interleukin-1 receptor antagonist protein isoform 2 (human), hIL1RN/iso:2
Yes
organism-sequence


PR:P18510-3 interleukin-1 receptor antagonist protein isoform 3 (human), hIL1RN/iso:3
Yes
organism-sequence


PR:P18510-4 interleukin-1 receptor antagonist protein isoform 4 (human), hIL1RN/iso:4
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036601 hIL1RN/iso:1/SigPep-
UniProtKB:P18510-1, 26-177 | PRO_0000015328
"An interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form in human. UniProtKB:P18510-1, 26-177." [PMID:2139180, PRO:CNA]		 enablesGO:0045352 interleukin-1 type I receptor antagonist activity PMID:2139180
located_inGO:0005615 extracellular space PMID:2139180
PR:P18510-2 hIL1RN/iso:2
interleukin-1 receptor antagonist protein isoform icIL-1ra (human)
"An interleukin-1 receptor antagonist protein isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P18510]		 located_inGO:0005615 extracellular space PMID:16564702
GO:0005622 intracellular anatomical structure PMID:1827201
PR:P18510-3 hIL1RN/iso:3
interleukin-1 receptor antagonist protein isoform icIL-1ra type II (human)
"An interleukin-1 receptor antagonist protein isoform 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P18510]		 located_inGO:0005622 intracellular anatomical structure PMID:7629520
PR:P18510-4 hIL1RN/iso:4

"An interleukin-1 receptor antagonist protein isoform 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P18510]		 located_inGO:0005622 intracellular anatomical structure PMID:12671514