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Protein Ontology report - DNA (cytosine-5)-methyltransferase 1 (human)
PR:P26358 -
http://purl.obolibrary.org/obo/PR_P26358
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P26358
PRO name
DNA (cytosine-5)-methyltransferase 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hDNMT1
Gene-based
:
RELATED:
AIM | CXXC9 | DNMT | DNMT1
Other
:
EXACT:
CXXC-type zinc finger protein 9 (human) | DNA methyltransferase HsaI (human) | DNA MTase HsaI (human) | Dnmt1 (human) | M.HsaI (human) | MCMT (human)
Definition
"A DNA (cytosine-5)-methyltransferase 1 that is encoded in the genome of human." [PRO:DNx,
UniProtKB:P26358
]
PRO Category
organism-gene
Parent
PR:000006606
DNA (cytosine-5)-methyltransferase 1
PR:000029067
Homo sapiens protein
Gene Template
HGNC:2976
DNMT1 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
3
Modification
0
Organism-Modification
16
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P26358
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P26358
DNA (cytosine-5)-methyltransferase 1 (human), hDNMT1
organism-sequence
PR:P26358-1
DNA (cytosine-5)-methyltransferase 1 isoform 1 (human), hDNMT1/iso:1
organism-sequence
PR:P26358-2
DNA (cytosine-5)-methyltransferase 1 isoform h2 (human), hDNMT1/iso:h2
organism-sequence
PR:P26358-3
DNA (cytosine-5)-methyltransferase 1 isoform h3 (human), hDNMT1/iso:h3
organism-modification
PR:000037504
DNA (cytosine-5)-methyltransferase 1 unphosphorylated 1 (human), hDNMT1/UnPhos:1
Yes
Yes
organism-modification
PR:000037505
DNA (cytosine-5)-methyltransferase 1 phosphorylated 1 (human), hDNMT1/Phos:1
Yes
organism-modification
PR:000037506
DNA (cytosine-5)-methyltransferase 1 phosphorylated 2 (human), hDNMT1/Phos:2
Yes
organism-modification
PR:000064669
DNA (cytosine-5)-methyltransferase 1 sumoylated form (human), hDNMT1/SumoLys+
organism-modification
PR:000064966
DNA (cytosine-5)-methyltransferase 1 cysteinylated 1 (human), hDNMT1/Cyst:1
organism-modification
PR:000072937
DNA (cytosine-5)-methyltransferase 1 deaminated 1 (human), hDNMT1/Deam:1
organism-modification
PR:000073186
DNA (cytosine-5)-methyltransferase 1 methylated 1 (human), hDNMT1/Me:1
organism-modification
PR:000075247
DNA (cytosine-5)-methyltransferase 1 cysteinylated 2 (human), hDNMT1/Cyst:2
organism-modification
PR:000076392
DNA (cytosine-5)-methyltransferase 1 hydroxylated 1 (human), hDNMT1/Hy:1
organism-modification
PR:000077299
DNA (cytosine-5)-methyltransferase 1 methylated 2 (human), hDNMT1/Me:2
organism-modification
PR:000077374
DNA (cytosine-5)-methyltransferase 1 methylated 3 (human), hDNMT1/Me:3
organism-modification
PR:000077466
DNA (cytosine-5)-methyltransferase 1 methylated 4 (human), hDNMT1/Me:4
organism-modification
PR:000081489
DNA (cytosine-5)-methyltransferase 1 methylated 5 (human), hDNMT1/Me:5
organism-modification
PR:000082192
DNA (cytosine-5)-methyltransferase 1 deaminated 2 (human), hDNMT1/Deam:2
organism-modification
PR:000082488
DNA (cytosine-5)-methyltransferase 1 cysteinylated 3 (human), hDNMT1/Cyst:3
organism-modification
PR:000084790
DNA (cytosine-5)-methyltransferase 1 cysteinylated 4 (human), hDNMT1/Cyst:4
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hDNMT1
forms found in complexes
hDNMT1
Component
Complexes
PR:000037504
hDNMT1/UnPhos:1
PR:000037517
DNMT1:PCNA:UHRF1 complex (human)
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037504
hDNMT1/UnPhos:1
UniProtKB:P26358, Ser-127/Ser-143, PR:000026291 | UniProtKB:P26358-1, Ser-127/Ser-143, PR:000026291
"A DNA (cytosine-5)-methyltransferase 1 (human) that lacks phosphorylation on residues at positions equivalent to Ser-127 and Ser-143 of the amino acid sequence represented by UniProtKB:P26358-1. Example: UniProtKB:P26358-1, Ser-127/Ser-143, PR:000026291." [PMID:20613874, PRO:KER]
enables
GO:0005515
protein binding
with
PR:P12004
cyclin (human)
PMID:20613874
GO:0005515
protein binding
with
PR:Q96T88
hNp95
PMID:20613874
PR:000037505
hDNMT1/Phos:1
UniProtKB:P26358, Ser-127, MOD:00046 | UniProtKB:P26358-1, Ser-127, MOD:00046 | pDnmt1S127
"A DNA (cytosine-5)-methyltransferase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-127 of the amino acid sequence represented by UniProtKB:P26358-1. Example: UniProtKB:P26358-1, Ser-127, MOD:00046." [PMID:20613874, PRO:KER]
enables
decreased
GO:0005515
protein binding
with
PR:P12004
cyclin (human)
PMID:20613874
decreased
GO:0005515
protein binding
with
PR:Q96T88
hNp95
PMID:20613874
PR:000037506
hDNMT1/Phos:2
UniProtKB:P26358, Ser-127/Ser-143, MOD:00046 | UniProtKB:P26358-1, Ser-127/Ser-143, MOD:00046 | pDnmt1S127/S143
"A DNA (cytosine-5)-methyltransferase 1 (human) that has been phosphorylated on residues at positions to Ser-127 and Ser-143 of the amino acid sequence represented by UniProtKB:P26358-1. Example: UniProtKB:P26358-1, Ser-127/Ser-143, MOD:00046." [PMID:20613874, PRO:KER]
enables
decreased
GO:0005515
protein binding
with
PR:P12004
cyclin (human)
PMID:20613874
decreased
GO:0005515
protein binding
with
PR:Q96T88
hNp95
PMID:20613874