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Protein Ontology report - tumor necrosis factor ligand superfamily member 6 (mouse)

PR:P41047 - http://purl.obolibrary.org/obo/PR_P41047

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PAF

GPI

PRO ID

PR:P41047

PRO name

tumor necrosis factor ligand superfamily member 6 (mouse)

Synonyms

PRO-Short-label:	EXACT:	mFASLG
Gene-based:	RELATED:	Apt1lg1 \| Cd95l \| Fasl \| Faslg \| gld \| Tnfsf6
Other:	EXACT:	CD178 (mouse) \| CD95 ligand (mouse) \| CD95-L (mouse) \| Fas antigen ligand (mouse) \| Fas ligand (mouse) \| FasL (mouse)

Definition

"A tumor necrosis factor ligand superfamily member 6 that is encoded in the genome of mouse." [OMA:P41047, PRO:DNx]

PRO Category

organism-gene

Parent

PR:000000095
PR:000029032

Gene Template

MGI:99255 Fasl (mouse)

Taxon

NCBITaxon:10090 Mus musculus

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	0	Organism-Gene	1
Sequence	0	Organism-Sequence	3
Modification	0	Organism-Modification	0

Term Hierarchy
Visualization

DAG:

OLS:

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Related Cross References
Db identifiers	UniProtKB:P41047

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

organism-gene

PR:P41047 tumor necrosis factor ligand superfamily member 6 (mouse), mFASLG

organism-sequence

PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse), mFASLG/iso:FasL

Yes

organism-sequence

PR:000036783 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (mouse), mFASLG/iso:FasL/var:F273L

Yes

organism-sequence

PR:P41047-2 tumor necrosis factor ligand superfamily member 6 isoform FasLS (mouse), mFASLG/iso:FasLS

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036783 mFASLG/iso:FasL/var:F273L UniProtKB:P41047-1, Phe-273, CHEBI:30006 \| Faslg isoform 1 sequence variant 1 (mouse) \| Faslg isoform FasL sequence variant 1 (mouse) \| tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (mouse) \| tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (mouse) \| gld	associated_with_disease_progression	DO:6688 autoimmune lymphoproliferative syndrome	PMID:7495745
	located_in	GO:0005886 plasma membrane	PMID:7495745
PR:P41047-1 mFASLG/iso:FasL	acts_upstream_of_or_within	GO:0006915 apoptotic process	PMID:16365167
		GO:0043066 negative regulation of apoptotic process	MGI:76989; PMID:7595210
		GO:0097190 apoptotic signaling pathway	PMID:15039234
	located_in	GO:0005886 plasma membrane	PMID:16973387
	located_in	GO:0009986 cell surface	PMID:16973387
PR:P41047-2 mFASLG/iso:FasLS	acts_upstream_of_or_within	GO:0043066 negative regulation of apoptotic process	PMID:10552956
PR:P41047-2 mFASLG/iso:FasLS	located_in	GO:0005615 extracellular space	PMID:10552956