PRO Term |
GO Annotation |
Evidence |
PR:000000200 hACVR1/var:R206H UniProtKB:Q04771, Arg-206, CHEBI:29979 | activin receptor type-1 sequence variant 1 (human) "An activin receptor type-1 (human) that has a His residue at the position equivalent to Arg-206 of the amino acid sequence represented by UniProtKB:Q04771. This variation is located within the GS-motif. UniProtKB:Q04771, Arg-206, CHEBI:29979." [PMID:8397373, PRO:CNA, PRO:DAN] |
associated_with_disease_progression | DO:13374 fibrodysplasia ossificans progressiva |
PMID:8397373 |
located_in | GO:0005886 plasma membrane |
PMID:8397373 |
PR:000036435 hACVR1/iso:1/SigPep-/Phos:1
"An activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in human." [PMID:8242742, PMID:8389764, PMID:8397373, PRO:CNA] |
acts_upstream_of_or_within | GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway |
PMID:8242742; PMID:8389764 |
enables | GO:0004675 transmembrane receptor protein serine/threonine kinase activity |
PMID:8389764 |
GO:0048185 activin binding |
PMID:8242742 |
located_in | GO:0005886 plasma membrane |
PMID:8242742; PMID:8397373 |
GO:0048179 activin receptor complex |
PMID:8242742 |