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Protein Ontology report - retinoblastoma-like protein 2 (human)
PR:Q08999 -
http://purl.obolibrary.org/obo/PR_Q08999
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:Q08999
PRO name
retinoblastoma-like protein 2 (human)
Synonyms
PRO-Short-label
:
EXACT:
hRBL2
Gene-based
:
RELATED:
RB2 | RBL2
Other
:
EXACT:
130 kDa retinoblastoma-associated protein (human) | pRb2 (human) | RBR-2 (human) | retinoblastoma-related protein 2 (human)
Definition
"A retinoblastoma-like protein 2 that is encoded in the genome of human." [PRO:CNA,
UniProtKB:Q08999
]
PRO Category
organism-gene
Parent
PR:000000119
PR:000029067
Gene Template
HGNC:9894
RBL2 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
2
Modification
0
Organism-Modification
5
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q08999
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:Q08999
retinoblastoma-like protein 2 (human), hRBL2
organism-sequence
PR:Q08999-1
retinoblastoma-like protein 2 isoform 1 (human), hRBL2/iso:1
Yes
organism-modification
PR:000036471
retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human), hRBL2/iso:1/Phos:1
Yes
organism-modification
PR:000036472
retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human), hRBL2/iso:1/Phos:2
Yes
organism-modification
PR:000036473
retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human), hRBL2/iso:1/Phos:3
Yes
organism-sequence
PR:Q08999-2
retinoblastoma-like protein 2 isoform h2 (human), hRBL2/iso:h2
organism-modification
PR:000049025
retinoblastoma-like protein 2 phosphorylated 4 (human), hRBL2/Phos:4
organism-modification
PR:000068308
retinoblastoma-like protein 2 phosphorylated 1 (human), hRBL2/Phos:1
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036471
hRBL2/iso:1/Phos:1
UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046
acts_upstream_of_or_within
GO:0051726
regulation of cell cycle
PMID:11042701
;
PMID:11157749
;
PMID:8710362
enables
NOT
GO:0005515
protein binding
PMID:11157749
NOT
GO:0030308
negative regulation of cell growth
PMID:11157749
PR:000036472
hRBL2/iso:1/Phos:2
UniProtKB:Q08999-1, Ser-672, MOD:00046
acts_upstream_of_or_within
GO:0051726
regulation of cell cycle
PMID:12006580
enables
GO:0005515
protein binding
with
PR:Q13309
cyclin-A/CDK2-associated protein p45 (human)
PMID:12006580
NOT
GO:0030308
negative regulation of cell growth
PMID:12006580
PR:000036473
hRBL2/iso:1/Phos:3
UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047
acts_upstream_of_or_within
GO:0051726
regulation of cell cycle
PMID:11042701
;
PMID:11157749
;
PMID:8710362
enables
GO:0005515
protein binding
with
PR:Q16254
E2F-4 (human)
PMID:11042701
;
PMID:11157749
PR:Q08999-1
hRBL2/iso:1
enables
GO:0005515
protein binding
PMID:8361765