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Protein Ontology report - Rho-associated protein kinase 1 (human)
PR:Q13464 - http://purl.obolibrary.org/obo/PR_Q13464
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q13464   
  PRO nameRho-associated protein kinase 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hROCK1
Gene-based: RELATED:ROCK1
Other: EXACT:p160 ROCK-1 (human) | p160ROCK (human) | renal carcinoma antigen NY-REN-35 (human) | Rho-associated, coiled-coil-containing protein kinase 1 (human) | Rho-associated, coiled-coil-containing protein kinase I (human) | ROCK-I (human)
  Definition"A Rho-associated protein kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13464] 
  PRO Categoryorganism-gene 
  ParentPR:000000120 Rho-associated protein kinase 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:10251 ROCK1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q13464
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q13464 Rho-associated protein kinase 1 (human), hROCK1

organism-sequence


PR:Q13464-1 Rho-associated protein kinase 1 isoform 1 (human), hROCK1/iso:1
Yes
organism-modification


PR:000026340 Rho-associated protein kinase 1 isoform 1 cleaved 1 (human), hROCK1/iso:1/Clv:1
Yes
organism-modification


PR:000044586 Rho-associated protein kinase 1 isoform 1 unmodified form (human), hROCK1/iso:1/UnMod
Yes
organism-modification


PR:000061208 Rho-associated protein kinase 1, initiator methionine removed form (human), hROCK1/InitMet-

organism-modification


PR:000070060 Rho-associated protein kinase 1 deaminated 1 (human), hROCK1/Deam:1

organism-modification


PR:000070524 Rho-associated protein kinase 1 phosphorylated 1 (human), hROCK1/Phos:1

organism-modification


PR:000082399 Rho-associated protein kinase 1 deaminated 2 (human), hROCK1/Deam:2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026340 hROCK1/iso:1/Clv:1
UniProtKB:Q13464-1, 1-1113
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in human. UniProtKB:Q13464-1, 1-1113." [PRO:DNx, UniProtKB:Q13464]		 acts_upstream_of_or_withinGO:0006468 protein phosphorylation PMID:11283607
enablesincreased GO:0004674 protein serine/threonine kinase activity relative to PR:000002529 ROCK1/iso:1/UnMod PMID:11283607
PR:000044586 hROCK1/iso:1/UnMod

"A Rho-associated protein kinase 1 isoform 1 unmodified form in human." [PRO:DNx]		 enablesGO:0004674 protein serine/threonine kinase activity PMID:15699075
GO:0004674 protein serine/threonine kinase activity PMID:15699075
PR:Q13464-1 hROCK1/iso:1

"A Rho-associated protein kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006468 protein phosphorylation PMID:10436159
GO:0007266 Rho protein signal transduction PMID:8798490
GO:0030036 actin cytoskeleton organization PMID:10436159
GO:0051260 protein homooligomerization PMID:15291762
enablesGO:0004674 protein serine/threonine kinase activity PMID:8798490
GO:0031267 small GTPase binding PMID:14660612; PMID:15475352