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Protein Ontology report - CREB-binding protein (human)
PR:Q92793 - http://purl.obolibrary.org/obo/PR_Q92793
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q92793   
  PRO nameCREB-binding protein (human) 
  Synonyms
PRO-Short-label: EXACT:hCREBBP
Gene-based: RELATED:CBP | CREBBP
Other: EXACT:histone lysine acetyltransferase CREBBP (human) | protein-lysine acetyltransferase CREBBP (human)
  Definition"A CREB-binding protein that is encoded in the genome of human." [PMID:11331617] 
  PRO Categoryorganism-gene 
  ParentPR:000000090
PR:000027108
  Gene TemplateHGNC:2348 CREBBP (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q92793
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q92793 CREB-binding protein (human), hCREBBP

organism-sequence


PR:000000266 CREB-binding protein sequence variant R1378P (human), hCREBBP/var:R1378P
Yes
organism-sequence


PR:Q92793-1 CREB-binding protein isoform 1 (human), hCREBBP/iso:1
Yes
organism-sequence


PR:Q92793-2 CREB-binding protein isoform h2 (human), hCREBBP/iso:h2

organism-modification


PR:000064816 CREB-binding protein sumoylated 1 (human), hCREBBP/Sumo:1

organism-modification


PR:000067783 CREB-binding protein phosphorylated 1 (human), hCREBBP/Phos:1

organism-modification


PR:000080126 CREB-binding protein phosphorylated 2 (human), hCREBBP/Phos:2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000266
hCREBBP/var:R1378P
UniProtKB:Q92793, Arg-1378, CHEBI:50342 | UniProtKB:Q92793-1, Arg-1378, CHEBI:50342 | CREB-binding protein sequence variant 1 (human)		 associated_with_disease_progressionDO:1933 Rubinstein-Taybi syndrome PMID:11331617
enablesNOT GO:0004402 histone acetyltransferase activity PMID:11331617
located_inSO:0001559 polypeptide_loss_of_function_variant PMID:11331617
PR:Q92793-1
hCREBBP/iso:1
 acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PMID:12169688; PMID:7913207
GO:0016573 histone acetylation PMID:11742995
GO:0045893 positive regulation of DNA-templated transcription PMID:11742995
enablesGO:0003713 transcription coactivator activity PMID:10733899; PMID:10893273; PMID:12169688; PMID:12586840; PMID:8684459
GO:0004402 histone acetyltransferase activity PMID:11742995
GO:0005515 protein binding with PR:P42858 HD PMID:11799127
GO:0005515 protein binding with PR:P55209 hNAP1L1 PMID:11799127
GO:0005515 protein binding with PR:Q04206 hRELA PMID:11799127
GO:0005515 protein binding with PR:Q14686 activating signal cointegrator 2 (human) PMID:11799127
GO:0005515 protein binding with PR:Q16665 ARNT-interacting protein (human) PMID:11799127
GO:0005515 protein binding with PR:Q92793 CBP PMID:11799127
GO:0005515 protein binding with PR:Q99967-1 PMID:11799127
GO:0005515 protein binding with PR:Q9UER7 BING2 PMID:11799127
GO:0005515 protein binding PMID:11799127
GO:0005515 protein binding PMID:11799127
GO:0016407 acetyltransferase activity PMID:11742995
located_inGO:0000123 histone acetyltransferase complex PMID:9742083
GO:0005634 nucleus PMID:7913207