T3 B cell
Definition:
A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM).
Exact Synonyms
An1 B cell
T3 B lymphocyte
T3 B-cell
T3 B-lymphocyte
transitional stage 3 B cell
class Information
in_subset
class Relations
Equivalent to
- (transitional stage B cellandparticipates inrosomeB cell anergygoandhas plasma membrane partrosomeIgD immunoglobulin complexgoandhas plasma membrane partrosomeIgM immunoglobulin complexgoandhas plasma membrane partrosomeL-selectinprandhas plasma membrane partrosomecomplement receptor type 2prandhas plasma membrane partrosomelow affinity immunoglobulin epsilon Fc receptorpr)
Subclass of
- transitional stage B cell
- participates inrosomeB cell anergygo
- has plasma membrane partrosomeIgD immunoglobulin complexgo
- has plasma membrane partrosomeL-selectinpr
- has plasma membrane partrosomecomplement receptor type 2pr
- has plasma membrane partrosomelow affinity immunoglobulin epsilon Fc receptorpr
- develops fromrosomeT2 B cell