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Protein Ontology report - tumor necrosis factor, TNF-like
PR:000000033 - http://purl.obolibrary.org/obo/PR_000000033
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000033   
  PRO nametumor necrosis factor, TNF-like 
  Definition"A protein that has a core domain composition consisting of an N-terminal cytosolic domain, a type II transmembrane domain and a C-terminal TNF domain (Pfam:PF00229)." [PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family2                                                  Organism-Family 0                                        
         Gene6                                                  Organism-Gene 17                                        
         Sequence12                                                  Organism-Sequence 20                                        
         Modification15                                                  Organism-Modification 21                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF001873
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000000033 tumor necrosis factor, TNF-like, fam:CBP-p300
Yes
gene


PR:000000095 tumor necrosis factor ligand superfamily member 6, FASLG
Yes
organism-gene


PR:P36940 tumor necrosis factor ligand superfamily member 6 (rat), rFASLG

organism-gene


PR:P41047 tumor necrosis factor ligand superfamily member 6 (mouse), mFASLG

organism-sequence


PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse), mFASLG/iso:FasL
Yes
organism-sequence


PR:000036783 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (mouse), mFASLG/iso:FasL/var:F273L
Yes
organism-sequence


PR:P41047-2 tumor necrosis factor ligand superfamily member 6 isoform FasLS (mouse), mFASLG/iso:FasLS
Yes
organism-gene


PR:P48023 tumor necrosis factor ligand superfamily member 6 (human), hFASLG

organism-sequence


PR:P48023-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (human), hFASLG/iso:FasL
Yes
organism-sequence


PR:000036782 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human), hFASLG/iso:FasL/var:F273L
Yes
organism-modification


PR:000036458 tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 (human), hFASLG/iso:FasL/NGlyco:1
Yes
organism-modification


PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human), hFASLG/iso:FasL/Clv:soluble
Yes
organism-sequence


PR:P48023-2 tumor necrosis factor ligand superfamily member 6 isoform h2 (human), hFASLG/iso:h2

sequence


PR:000000276 tumor necrosis factor ligand superfamily member 6 isoform FasL, FASLG/iso:FasL

sequence


PR:000000278 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L, FASLG/iso:FasL/var:F273L

organism-sequence


PR:000036782 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human), hFASLG/iso:FasL/var:F273L
Yes
organism-sequence


PR:000036783 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (mouse), mFASLG/iso:FasL/var:F273L
Yes
organism-sequence


PR:P41047-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (mouse), mFASLG/iso:FasL
Yes
organism-sequence


PR:000036783 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (mouse), mFASLG/iso:FasL/var:F273L
Yes
organism-sequence


PR:P48023-1 tumor necrosis factor ligand superfamily member 6 isoform FasL (human), hFASLG/iso:FasL
Yes
organism-sequence


PR:000036782 tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L (human), hFASLG/iso:FasL/var:F273L
Yes
organism-modification


PR:000036458 tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 (human), hFASLG/iso:FasL/NGlyco:1
Yes
organism-modification


PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human), hFASLG/iso:FasL/Clv:soluble
Yes
modification


PR:000000432 tumor necrosis factor ligand superfamily member 6 isoform FasL glycosylated form, FASLG/iso:FasL/GlycoRes+

modification


PR:000000546 tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1, FASLG/iso:FasL/NGlyco:1

organism-modification


PR:000036458 tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 (human), hFASLG/iso:FasL/NGlyco:1
Yes
modification


PR:000000547 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form, FASLG/iso:FasL/Clv:soluble

organism-modification


PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human), hFASLG/iso:FasL/Clv:soluble
Yes
sequence


PR:000000277 tumor necrosis factor ligand superfamily member 6 isoform FasLS, FASLG/iso:FasLS

organism-sequence


PR:P41047-2 tumor necrosis factor ligand superfamily member 6 isoform FasLS (mouse), mFASLG/iso:FasLS
Yes
modification


PR:000018277 tumor necrosis factor ligand superfamily member 6 proteolytic cleavage product, FASLG/ClvPrd

modification


PR:000000547 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form, FASLG/iso:FasL/Clv:soluble

organism-modification


PR:000036459 tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form (human), hFASLG/iso:FasL/Clv:soluble
Yes
gene


PR:000000134 tumor necrosis factor, TNF

organism-gene


PR:P01375 tumor necrosis factor (human), hTNF

Yes
organism-sequence


PR:P01375-1 tumor necrosis factor isoform 1 (human), hTNF/iso:1
Yes
organism-modification


PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human), hTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036507 tumor necrosis factor isoform 1 myristoylated 1 (human), hTNF/iso:1/Myr:1
Yes
organism-modification


PR:000036508 tumor necrosis factor isoform 1 phosphorylated 1 (human), hTNF/iso:1/Phos:1
Yes
organism-modification


PR:000051774 tumor necrosis factor O-glycosylated 1 (human), hTNF/OGlyco:1

organism-modification


PR:000051775 tumor necrosis factor O-glycosylated 2 (human), hTNF/OGlyco:2

organism-gene


PR:P06804 tumor necrosis factor (mouse), mTNF

organism-sequence


PR:P06804-1 tumor necrosis factor isoform 1 (mouse), mTNF/iso:1

organism-modification


PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse), mTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036506 tumor necrosis factor isoform 1 cleaved 2 (mouse), mTNF/iso:1/Clv:2
Yes
organism-gene


PR:P16599 tumor necrosis factor (rat), rTNF

sequence


PR:000000381 tumor necrosis factor isoform 1, TNF/iso:1

organism-sequence


PR:P01375-1 tumor necrosis factor isoform 1 (human), hTNF/iso:1
Yes
organism-modification


PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human), hTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036507 tumor necrosis factor isoform 1 myristoylated 1 (human), hTNF/iso:1/Myr:1
Yes
organism-modification


PR:000036508 tumor necrosis factor isoform 1 phosphorylated 1 (human), hTNF/iso:1/Phos:1
Yes
organism-sequence


PR:P06804-1 tumor necrosis factor isoform 1 (mouse), mTNF/iso:1

organism-modification


PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse), mTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036506 tumor necrosis factor isoform 1 cleaved 2 (mouse), mTNF/iso:1/Clv:2
Yes
modification


PR:000000496 tumor necrosis factor isoform 1 myristoylated form, TNF/iso:1/MyrRes+

modification


PR:000000606 tumor necrosis factor isoform 1 myristoylated 1, TNF/iso:1/Myr:1

organism-modification


PR:000036507 tumor necrosis factor isoform 1 myristoylated 1 (human), hTNF/iso:1/Myr:1
Yes
modification


PR:000000497 tumor necrosis factor isoform 1 phosphorylated form, TNF/iso:1/PhosRes+

modification


PR:000000607 tumor necrosis factor isoform 1 phosphorylated 1, TNF/iso:1/Phos:1

organism-modification


PR:000036508 tumor necrosis factor isoform 1 phosphorylated 1 (human), hTNF/iso:1/Phos:1
Yes
modification


PR:000000604 tumor necrosis factor isoform 1 cleaved 1, TNF/iso:1/Clv:1

organism-modification


PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human), hTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse), mTNF/iso:1/Clv:1
Yes
modification


PR:000000605 tumor necrosis factor isoform 1 cleaved 2, TNF/iso:1/Clv:2

organism-modification


PR:000036506 tumor necrosis factor isoform 1 cleaved 2 (mouse), mTNF/iso:1/Clv:2
Yes
modification


PR:000018285 tumor necrosis factor proteolytic cleavage product, TNF/ClvPrd

modification


PR:000000604 tumor necrosis factor isoform 1 cleaved 1, TNF/iso:1/Clv:1

organism-modification


PR:000036504 tumor necrosis factor isoform 1 cleaved 1 (human), hTNF/iso:1/Clv:1
Yes
organism-modification


PR:000036505 tumor necrosis factor isoform 1 cleaved 1 (mouse), mTNF/iso:1/Clv:1
Yes
modification


PR:000000605 tumor necrosis factor isoform 1 cleaved 2, TNF/iso:1/Clv:2

organism-modification


PR:000036506 tumor necrosis factor isoform 1 cleaved 2 (mouse), mTNF/iso:1/Clv:2
Yes
gene


PR:000002222 tumor necrosis factor ligand superfamily member 14, TNFSF14

organism-gene


PR:O43557 tumor necrosis factor ligand superfamily member 14 (human), hTNFSF14

organism-sequence


PR:O43557-1 tumor necrosis factor ligand superfamily member 14 isoform 1 (human), hTNFSF14/iso:1

organism-sequence


PR:O43557-2 tumor necrosis factor ligand superfamily member 14 isoform 2 (human), hTNFSF14/iso:2

organism-modification


PR:000065924 tumor necrosis factor ligand superfamily member 14 deaminated 1 (human), hTNFSF14/Deam:1

organism-modification


PR:000082240 tumor necrosis factor ligand superfamily member 14 phosphorylated 1 (human), hTNFSF14/Phos:1

organism-gene


PR:Q9QYH9 tumor necrosis factor ligand superfamily member 14 (mouse), mTNFSF14

organism-sequence


PR:Q9QYH9-1 tumor necrosis factor ligand superfamily member 14 isoform 1 (mouse), mTNFSF14/iso:1

sequence


PR:000002353 tumor necrosis factor ligand superfamily member 14 isoform 1, TNFSF14/iso:1

organism-sequence


PR:O43557-1 tumor necrosis factor ligand superfamily member 14 isoform 1 (human), hTNFSF14/iso:1

organism-sequence


PR:Q9QYH9-1 tumor necrosis factor ligand superfamily member 14 isoform 1 (mouse), mTNFSF14/iso:1

sequence


PR:000002354 tumor necrosis factor ligand superfamily member 14 isoform 2, TNFSF14/iso:2

organism-sequence


PR:O43557-2 tumor necrosis factor ligand superfamily member 14 isoform 2 (human), hTNFSF14/iso:2

modification


PR:000018755 tumor necrosis factor ligand superfamily member 14 proteolytic cleavage product, TNFSF14/ClvPrd

gene


PR:000002223 tumor necrosis factor ligand superfamily member 15, TNFSF15

organism-gene


PR:O95150 tumor necrosis factor ligand superfamily member 15 (human), hTNFSF15

organism-sequence


PR:O95150-1 tumor necrosis factor ligand superfamily member 15 isoform 1 (human), hTNFSF15/iso:1

organism-sequence


PR:O95150-2 tumor necrosis factor ligand superfamily member 15 isoform 2 (human), hTNFSF15/iso:2

organism-sequence


PR:O95150-3 tumor necrosis factor ligand superfamily member 15 isoform 3 (human), hTNFSF15/iso:3

organism-gene


PR:Q50L61 TL1A (chicken), chick-TNFSF15

organism-gene


PR:Q5UBV8 tumor necrosis factor ligand superfamily member 15 (mouse), mTNFSF15

organism-sequence


PR:Q5UBV8-1 tumor necrosis factor ligand superfamily member 15 isoform 1 (mouse), mTNFSF15/iso:1

organism-gene


PR:Q8K3Y7 tumor necrosis factor ligand superfamily member 15 (rat), rTNFSF15

sequence


PR:000002355 tumor necrosis factor ligand superfamily member 15 isoform 1, TNFSF15/iso:1

organism-sequence


PR:O95150-1 tumor necrosis factor ligand superfamily member 15 isoform 1 (human), hTNFSF15/iso:1

organism-sequence


PR:Q5UBV8-1 tumor necrosis factor ligand superfamily member 15 isoform 1 (mouse), mTNFSF15/iso:1

sequence


PR:000002356 tumor necrosis factor ligand superfamily member 15 isoform 2, TNFSF15/iso:2

organism-sequence


PR:O95150-2 tumor necrosis factor ligand superfamily member 15 isoform 2 (human), hTNFSF15/iso:2

sequence


PR:000002357 tumor necrosis factor ligand superfamily member 15 isoform 3, TNFSF15/iso:3

organism-sequence


PR:O95150-3 tumor necrosis factor ligand superfamily member 15 isoform 3 (human), hTNFSF15/iso:3

modification


PR:000018756 tumor necrosis factor ligand superfamily member 15 proteolytic cleavage product, TNFSF15/ClvPrd

family


PR:000050043 lymphotoxin, fam:LT

gene


PR:000002204 lymphotoxin-alpha, LTA

organism-gene


PR:P01374 lymphotoxin-alpha (human), hLTA

organism-sequence


PR:P01374-1 lymphotoxin-alpha isoform 1 (human), hLTA/iso:1

organism-modification


PR:000048265 lymphotoxin-alpha, signal peptide removed form (human), hLTA/SigPep-

organism-modification


PR:000051768 lymphotoxin-alpha N-glycosylated 1 (human), hLTA/NGlyco:1

organism-modification


PR:000051769 lymphotoxin-alpha N-glycosylated 2 (human), hLTA/NGlyco:2

organism-modification


PR:000051770 lymphotoxin-alpha N-glycosylated 3 (human), hLTA/NGlyco:3

organism-modification


PR:000051771 lymphotoxin-alpha N-glycosylated 4 (human), hLTA/NGlyco:4

organism-modification


PR:000051772 lymphotoxin-alpha N-glycosylated 5 (human), hLTA/NGlyco:5

organism-modification


PR:000051773 lymphotoxin-alpha N-glycosylated 6 (human), hLTA/NGlyco:6

organism-modification


PR:000066956 lymphotoxin-alpha deaminated 1 (human), hLTA/Deam:1

organism-modification


PR:000073774 lymphotoxin-alpha methylated 1 (human), hLTA/Me:1

organism-modification


PR:000074173 lymphotoxin-alpha deaminated 2 (human), hLTA/Deam:2

organism-gene


PR:P09225 lymphotoxin-alpha (mouse), mLTA

organism-sequence


PR:P09225-1 lymphotoxin-alpha isoform 1 (mouse), mLTA/iso:1

organism-gene


PR:Q06332 lymphotoxin-alpha (rat), rLTA

sequence


PR:000002331 lymphotoxin-alpha isoform 1, LTA/iso:1

organism-sequence


PR:P01374-1 lymphotoxin-alpha isoform 1 (human), hLTA/iso:1

organism-sequence


PR:P09225-1 lymphotoxin-alpha isoform 1 (mouse), mLTA/iso:1

modification


PR:000026648 lymphotoxin-alpha isoform 1, signal peptide removed form, LTA/iso:1/SigPep-

modification


PR:000018753 lymphotoxin-alpha, signal peptide removed form, LTA/SigPep-

modification


PR:000026648 lymphotoxin-alpha isoform 1, signal peptide removed form, LTA/iso:1/SigPep-

organism-modification


PR:000048265 lymphotoxin-alpha, signal peptide removed form (human), hLTA/SigPep-

gene


PR:000002205 lymphotoxin-beta, LTB

organism-gene


PR:P41155 lymphotoxin-beta (mouse), mLTB

organism-sequence


PR:P41155-1 lymphotoxin-beta isoform 1 (mouse), mLTB/iso:1

organism-gene


PR:Q06643 lymphotoxin-beta (human), hLTB

organism-sequence


PR:Q06643-1 lymphotoxin-beta isoform 1 (human), hLTB/iso:1

organism-sequence


PR:Q06643-2 lymphotoxin-beta isoform h2 (human), hLTB/iso:h2

sequence


PR:000002332 lymphotoxin-beta isoform 1, LTB/iso:1

organism-sequence


PR:P41155-1 lymphotoxin-beta isoform 1 (mouse), mLTB/iso:1

sequence


PR:000002333 lymphotoxin-beta isoform 2, LTB/iso:2

organism-sequence


PR:Q06643-1 lymphotoxin-beta isoform 1 (human), hLTB/iso:1

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fam:CBP-p300 forms found in complexes   

fam:CBP-p300 Component
 Complexes
PR:P01375 hTNF PR:000028432 TNF-alpha:TNF-R1:TRAPP:RIP1:TRAF2 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000033 fam:CBP-p300

"A protein that has a core domain composition consisting of an N-terminal cytosolic domain, a type II transmembrane domain and a C-terminal TNF domain (Pfam:PF00229)." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PIRSF:PIRSF001873
GO:0007165 signal transduction PIRSF:PIRSF001873
enablesGO:0005125 cytokine activity PIRSF:PIRSF001873
PR:000000095 FASLG
APT1LG1 | CD95L | FASL | gld | TNFSF6 | apoptosis antigen ligand | APTL | CD178 | CD95 ligand | CD95-L | fas antigen ligand | fas ligand | fas ligand, TNF-like
"A tumor necrosis factor, TNF-like that is a translation product of the human FASLG gene or a 1:1 ortholog thereof." [PRO:CNA]		 acts_upstream_of_or_withinGO:0007267 cell-cell signaling PANTHER:PTHR11471
PR:000036458 hFASLG/iso:FasL/NGlyco:1
UniProtKB:P48023-1, Asn-184/Asn-250/Asn-260, MOD:00160
"A tumor necrosis factor ligand superfamily member 6 isoform FasL N-glycosylated 1 in human. UniProtKB:P48023-1, Asn-184/Asn-250/Asn-260, MOD:00160." [PMID:9405425, PRO:CNA, PRO:DAN]		 acts_upstream_of_or_withinGO:0097190 apoptotic signaling pathway PMID:9405425
enablesGO:0005102 signaling receptor binding PMID:9405425
PR:000036459 hFASLG/iso:FasL/Clv:soluble
UniProtKB:P48023-1, 130-281 | PRO_0000034501
"A tumor necrosis factor ligand superfamily member 6 isoform FasL soluble form in human. UniProtKB:P48023-1, 130-281." [PMID:7536672, PMID:9228058, PMID:9396774, PMID:9405425, PRO:CNA]		 acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:9396774
enablesGO:0005102 signaling receptor binding PMID:9405425
GO:0042802 identical protein binding PMID:7536672; PMID:9228058; PMID:9405425
located_inGO:0005615 extracellular space PMID:7536672
PR:000036504 hTNF/iso:1/Clv:1
UniProtKB:P01375-1, 77-233 | PRO_0000034424
"A tumor necrosis factor isoform 1 cleaved 1 in human. UniProtKB:P01375-1, 77-233." [PMID:14512626, PMID:3856324, PRO:CNA]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:3856324
enablesGO:0005164 tumor necrosis factor receptor binding with PR:P19438 CD120a (human) PMID:14512626
GO:0042802 identical protein binding PMID:14512626
PR:000036505 mTNF/iso:1/Clv:1
UniProtKB:P06804-1, 80-235 | PRO_0000034436
"A tumor necrosis factor isoform 1 cleaved 1 in mouse. UniProtKB:P06804-1, 80-235." [PMID:10089307, PMID:9305915, PRO:CNA]		 acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PMID:9305915
located_inGO:0005615 extracellular space PMID:10089307
PR:000036506 mTNF/iso:1/Clv:2
UniProtKB:P06804-1, 70-235
"A tumor necrosis factor isoform 1 cleaved 2 in mouse. UniProtKB:P06804-1, 70-235." [PMID:2777790, PRO:CNA]		 enablesNOT GO:0005125 cytokine activity PMID:2777790
located_inGO:0005576 extracellular region PMID:2777790
PR:000036507 hTNF/iso:1/Myr:1
UniProtKB:P01375-1, Lys-19/Lys-20, MOD:00087
"A tumor necrosis factor isoform 1 myristoylated 1 in human. UniProtKB:P01375-1, Lys-19/Lys-20, MOD:00087." [PMID:1402651, PRO:CNA]		 located_inGO:0016020 membrane PMID:1402651
PR:000036508 hTNF/iso:1/Phos:1
UniProtKB:P01375-1, Ser-2, MOD:00046
"A tumor necrosis factor isoform 1 phosphorylated 1 in human. UniProtKB:P01375-1, Ser-2, MOD:00046." [PMID:10205166, PMID:8597870, PRO:CNA]		 located_inGO:0016020 membrane PMID:10205166
PR:000036782 hFASLG/iso:FasL/var:F273L
UniProtKB:P48023-1, Phe-275, CHEBI:30006 | FASLG isoform 1 sequence variant 1 (human) | FASLG isoform FasL sequence variant 1 (human) | tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (human) | tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (human) | gld
"A tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L that is encoded in the genome of human. The variation occurs at the position equivalent to Phe-275 of the amino acid sequence represented by UniProtKB:P48023-1. UniProtKB:P48023-1, Phe-275, CHEBI:30006." [PRO:DAN]		 enablesaltered GO:0005102 signaling receptor binding with PR:P25445 apo-1 antigen (human) PMID:9405425
GO:0042802 identical protein binding PMID:9405425
located_inGO:0009986 cell surface PMID:9405425
PR:000036783 mFASLG/iso:FasL/var:F273L
UniProtKB:P41047-1, Phe-273, CHEBI:30006 | Faslg isoform 1 sequence variant 1 (mouse) | Faslg isoform FasL sequence variant 1 (mouse) | tumor necrosis factor ligand superfamily member 6 isoform 1 sequence variant 1 (mouse) | tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant 1 (mouse) | gld
"A tumor necrosis factor ligand superfamily member 6 isoform FasL sequence variant F273L that is encoded in the genome of mouse. The variation occurs at the position equivalent to Phe-273 of the amino acid sequence represented by UniProtKB:P41047-1. UniProtKB:P41047-1, Phe-273, CHEBI:30006." [PMID:7495745, PRO:DAN]		 associated_with_disease_progressionDO:6688 autoimmune lymphoproliferative syndrome PMID:7495745
located_inGO:0005886 plasma membrane PMID:7495745
PR:P01375-1 hTNF/iso:1

"A tumor necrosis factor isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:3856324
located_inGO:0005886 plasma membrane PMID:3349526
PR:P41047-1 mFASLG/iso:FasL

"A tumor necrosis factor ligand superfamily member 6 isoform FasL that is encoded in the genome of mouse." [PRO:CNA]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:16365167
GO:0043066 negative regulation of apoptotic process MGI:76989; PMID:7595210
GO:0097190 apoptotic signaling pathway PMID:15039234
located_inGO:0005886 plasma membrane PMID:16973387
GO:0009986 cell surface PMID:16973387
PR:P41047-2 mFASLG/iso:FasLS

"A tumor necrosis factor ligand superfamily member 6 isoform FasLS that is encoded in the genome of mouse." [PRO:CNA]		 acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:10552956
located_inGO:0005615 extracellular space PMID:10552956
PR:P48023-1 hFASLG/iso:FasL
FASLG isoform 1 (human) | tumor necrosis factor ligand superfamily member 6 isoform 1 (human)
"A tumor necrosis factor ligand superfamily member 6 isoform FasL that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0043123 positive regulation of canonical NF-kappaB signal transduction PMID:12761501