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Protein Ontology report - TGF-beta receptor type-2 isoform RII-1
PR:000000048 - http://purl.obolibrary.org/obo/PR_000000048
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000048   
  PRO nameTGF-beta receptor type-2 isoform RII-1 
  Synonyms
PRO-Short-label: EXACT:TGFBR2/iso:RII-1
Other: EXACT:TGF-beta receptor isoform 1 | TGFBR2 isoform 1
  Definition"A TGF-beta receptor type-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62312-2 or a 1:1 ortholog thereof." [PMID:7957954, PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000005
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification5                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000048 TGF-beta receptor type-2 isoform RII-1, TGFBR2/iso:RII-1

organism-sequence


PR:P37173-1 TGF-beta receptor type-2 isoform RII-1 (human), hTGFBR2/iso:RII-1

organism-modification


PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human), hTGFBR2/iso:RII-1/SigPep-
Yes
organism-modification


PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human), hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes
organism-sequence


PR:Q62312-2 TGF-beta receptor type-2 isoform RII-1 (mouse), mTGFBR2/iso:RII-1
Yes
modification


PR:000000198 TGF-beta receptor type-2 isoform RII-1 phosphorylated form, TGFBR2/iso:RII-1/PhosRes+

modification


PR:000000410 TGF-beta receptor type-2 isoform RII-1 phosphorylated 1, TGFBR2/iso:RII-1/Phos:1

modification


PR:000003175 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated form, TGFBR2/iso:RII-1/SigPep-/PhosRes+

modification


PR:000003176 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1, TGFBR2/iso:RII-1/SigPep-/Phos:1

Yes
organism-modification


PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human), hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes
modification


PR:000000409 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form, TGFBR2/iso:RII-1/SigPep-

modification


PR:000003175 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated form, TGFBR2/iso:RII-1/SigPep-/PhosRes+

modification


PR:000003176 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1, TGFBR2/iso:RII-1/SigPep-/Phos:1

Yes
organism-modification


PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human), hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes
organism-modification


PR:000036408 TGF-beta receptor type-2 isoform RII-1, signal peptide removed form (human), hTGFBR2/iso:RII-1/SigPep-
Yes
organism-modification


PR:000025962 TGF-beta receptor type-2 isoform RII-1, signal peptide removed phosphorylated 1 (human), hTGFBR2/iso:RII-1/SigPep-/Phos:1

Yes
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TGFBR2/iso:RII-1 forms found in complexes   

TGFBR2/iso:RII-1 Component
 Complexes
PR:000003176 TGFBR2/iso:RII-1/SigPep-/Phos:1 PR:000025976
PR:000025962 hTGFBR2/iso:RII-1/SigPep-/Phos:1 PR:000025963
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036408
hTGFBR2/iso:RII-1/SigPep-
UniProtKB:P37173-1, 23-567 | hTGFBR2/iso:1/SigPep- | PRO_0000024426 | TGF-beta receptor type-2 isoform 1, signal peptide removed form (human)		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:11483955
GO:0007181 transforming growth factor beta receptor complex assembly PMID:1310899; PMID:8774881
enablesGO:0005026 transforming growth factor beta receptor activity, type II PMID:11483955
GO:0005515 protein binding with PR:000000634 TGFB3/iso:1/Clv:1 PMID:1850637
GO:0005515 protein binding PMID:1850637
GO:0050431 transforming growth factor beta binding PMID:11850637; PMID:1310899
located_inGO:0016020 membrane PMID:1310899
PR:Q62312-2
mTGFBR2/iso:RII-1
 located_inGO:0016020 membrane PMID:7957954