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Protein Ontology report - TGF-beta receptor type-2 sequence variant N435S (human) PR:000000062 - http://purl.obolibrary.org/obo/PR_000000062        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000000062      PRO name TGF-beta receptor type-2 sequence variant N435S (human)    Synonyms PRO-Short-label: EXACT: hTGFBR2/var:N435S PRO-proteoform-std: EXACT: UniProtKB:P37173, Asn-435, CHEBI:29999 NARROW: UniProtKB:P37173-1, Asn-435, CHEBI:29999 Other: EXACT: TGF-beta receptor type-2 sequence variant 6 (human)   Definition "A TGF-beta receptor type-2 (human) that has a Ser residue at the position equivalent to Asn-435 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Asn-435, CHEBI:29999." [PMID:11212236, PRO:CNA, PRO:DAN]    PRO Category organism-sequence    Parent PR:P37173 TGF-beta receptor type-2 (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Related Cross References   Db identifiers UniProtKB_VAR:VAR_022356 Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000000062 hTGFBR2/var:N435S UniProtKB:P37173, Asn-435, CHEBI:29999 | UniProtKB:P37173-1, Asn-435, CHEBI:29999 | TGF-beta receptor type-2 sequence variant 6 (human) "A TGF-beta receptor type-2 (human) that has a Ser residue at the position equivalent to Asn-435 of the amino acid sequence represented by UniProtKB:P37173-1. Example: UniProtKB:P37173-1, Asn-435, CHEBI:29999." [PMID:11212236, PRO:CNA, PRO:DAN] acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11212236 enables decreased GO:0005026 transforming growth factor beta receptor activity, type II relative to PR:000000409 TGF-beta receptor type-2 isoform 1 cleaved 1 PMID:11212236