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Protein Ontology report - CREB-binding protein isoform 1

PR:000000265 - http://purl.obolibrary.org/obo/PR_000000265

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000000265

PRO name

CREB-binding protein isoform 1

Synonyms

PRO-Short-label:

EXACT:

CREBBP/iso:1

Definition

"A CREB-binding protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92793-1 or a 1:1 ortholog thereof." [PRO:CNA]

PRO Category

sequence

Parent

PR:000000090

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Sequence	1	Organism-Sequence	2
Modification	3	Organism-Modification	1

Term Hierarchy
Visualization

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OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

sequence

PR:000000265 CREB-binding protein isoform 1, CREBBP/iso:1

organism-sequence

PR:P45481-1 CREB-binding protein isoform 1 (mouse), mCREBBP/iso:1

Yes

organism-modification

PR:000036453 CREB-binding protein isoform 1 methylated 1 (mouse), mCREBBP/iso:1/Me:1

Yes

organism-sequence

PR:Q92793-1 CREB-binding protein isoform 1 (human), hCREBBP/iso:1

Yes

modification

PR:000000426 CREB-binding protein isoform 1 methylated form, CREBBP/iso:1/MeRes+

modification

PR:000000541 CREB-binding protein isoform 1 methylated 1, CREBBP/iso:1/Me:1

organism-modification

PR:000036453 CREB-binding protein isoform 1 methylated 1 (mouse), mCREBBP/iso:1/Me:1

Yes

modification

PR:000026573 CREB-binding protein isoform 1, initiator methionine removed form, CREBBP/iso:1/InitMet-

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036453 mCREBBP/iso:1/Me:1 UniProtKB:P45481-1, Arg-600/Arg-624, MOD:00658	located_in	NOT GO:0000123 histone acetyltransferase complex	PMID:11701890
	located_in	GO:0005634 nucleus	PMID:11701890
PR:P45481-1 mCREBBP/iso:1	acts_upstream_of_or_within	GO:0045893 positive regulation of DNA-templated transcription	PMID:15464984
	enables	GO:0004402 histone acetyltransferase activity	PMID:11867645
		GO:0005515 protein binding with PR:P88946 orfK9 (tax435895)	PMID:12496368
		GO:0005515 protein binding with PR:Q60749 GAP-associated tyrosine phosphoprotein p62 (mouse)	PMID:12496368
		GO:0005515 protein binding	PMID:12496368
		GO:0016407 acetyltransferase activity	PMID:12496368
	located_in	GO:0005634 nucleus	PMID:11963968; PMID:12496368
PR:Q92793-1 hCREBBP/iso:1	acts_upstream_of_or_within	GO:0006355 regulation of DNA-templated transcription	PMID:12169688; PMID:7913207
		GO:0016573 histone acetylation	PMID:11742995
		GO:0045893 positive regulation of DNA-templated transcription	PMID:11742995
	enables	GO:0003713 transcription coactivator activity	PMID:10733899; PMID:10893273; PMID:12169688; PMID:12586840; PMID:8684459
		GO:0004402 histone acetyltransferase activity	PMID:11742995
		GO:0005515 protein binding with PR:P42858 HD	PMID:11799127
		GO:0005515 protein binding with PR:P55209 hNAP1L1	PMID:11799127
		GO:0005515 protein binding with PR:Q04206 hRELA	PMID:11799127
		GO:0005515 protein binding with PR:Q14686 activating signal cointegrator 2 (human)	PMID:11799127
		GO:0005515 protein binding with PR:Q16665 ARNT-interacting protein (human)	PMID:11799127
		GO:0005515 protein binding with PR:Q92793 CBP	PMID:11799127
		GO:0005515 protein binding with PR:Q99967-1	PMID:11799127
		GO:0005515 protein binding with PR:Q9UER7 BING2	PMID:11799127
		GO:0005515 protein binding	PMID:11799127
		GO:0005515 protein binding	PMID:11799127
		GO:0016407 acetyltransferase activity	PMID:11742995
	located_in	GO:0000123 histone acetyltransferase complex	PMID:9742083
	located_in	GO:0005634 nucleus	PMID:7913207