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Protein Ontology report - lefty 2 isoform 1
PR:000000451 - http://purl.obolibrary.org/obo/PR_000000451
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000451   
  PRO namelefty 2 isoform 1 
  Synonyms
PRO-Short-label: EXACT:LEFTY2/iso:1
  Definition"A lefty 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00292-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000000288 lefty 2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000000451 lefty 2 isoform 1, LEFTY2/iso:1

organism-sequence


PR:O00292-1 left-right determination factor 2 isoform 1 (human), hLEFTY2/iso:1
Yes
organism-modification


PR:000036549 lefty 2 isoform 1 cleaved 1 (human), hLEFTY2/iso:1/Clv:1
Yes
organism-modification


PR:000036550 lefty 2 isoform 1 cleaved 2 (human), hLEFTY2/iso:1/Clv:2
Yes
organism-sequence


PR:P57785-1 left-right determination factor 2 isoform 1 (mouse), mLEFTY2/iso:1

modification


PR:000000645 lefty 2 isoform 1 cleaved 1, LEFTY2/iso:1/Clv:1

organism-modification


PR:000036549 lefty 2 isoform 1 cleaved 1 (human), hLEFTY2/iso:1/Clv:1
Yes
modification


PR:000000646 lefty 2 isoform 1 cleaved 2, LEFTY2/iso:1/Clv:2

organism-modification


PR:000036550 lefty 2 isoform 1 cleaved 2 (human), hLEFTY2/iso:1/Clv:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036549 hLEFTY2/iso:1/Clv:1
UniProtKB:O00292-1, 77-366 | PRO_0000033807
"A lefty 2 isoform 1 cleaved 1 in human. UniProtKB:O00292-1, 77-366." [PMID:10053005, PMID:11278322, PRO:CNA]		 acts_upstream_of_or_withinGO:0007275 multicellular organism development PMID:10053005
GO:0007309 oocyte axis specification PMID:10053005
located_inGO:0005615 extracellular space PMID:11278322
PR:000036550 hLEFTY2/iso:1/Clv:2
UniProtKB:O00292-1, 135-366
"A lefty 2 isoform 1 cleaved 2 in human. UniProtKB:O00292-1, 135-366." [PMID:11278322, PRO:CNA]		 acts_upstream_of_or_withinGO:0043406 positive regulation of MAP kinase activity PMID:11278322
located_inGO:0005615 extracellular space PMID:11278322
PR:O00292-1 hLEFTY2/iso:1

"A lefty 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]		 acts_upstream_of_or_withinGO:0007275 multicellular organism development PMID:10053005
GO:0007309 oocyte axis specification PMID:10053005