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Protein Ontology report - fungal/metazoan cullin-1 isoform 1 neddylated 1
PR:000000542 - http://purl.obolibrary.org/obo/PR_000000542
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000542   
  PRO namefungal/metazoan cullin-1 isoform 1 neddylated 1 
  Synonyms
PRO-Short-label: EXACT:CUL1/iso:1/Nedd:1
  Definition"A fungal/metazoan cullin-1 isoform 1 neddylated form that has been neddylated in the conserved Lys residue within the IVR[ILV]MKxR[RK] motif. Example: UniProtKB:Q13616-1, Lys-720, MOD:01150." [PMID:10713156] 
  PRO Categorymodification 
  ParentPR:000000427 fungal/metazoan cullin-1 isoform 1 neddylated form
  TaxonNCBITaxon:33154 Opisthokonta
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000000542 fungal/metazoan cullin-1 isoform 1 neddylated 1, CUL1/iso:1/Nedd:1

organism-modification


PR:000036454 cullin-1 isoform 1 neddylated 1 (human), hCUL1/iso:1/Nedd:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036454 hCUL1/iso:1/Nedd:1
UniProtKB:Q13616-1, Lys-720, MOD:01150
"A fungal/metazoan cullin-1 isoform 1 neddylated 1 in human. UniProtKB:Q13616-1, Lys-720, MOD:01150." [PMID:10713156, PMID:10921923, PMID:17098746, PMID:8681378, PRO:CNA]		 acts_upstream_of_or_withinGO:0008285 negative regulation of cell population proliferation PMID:8681378
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PMID:10713156; PMID:10921923
GO:0051726 regulation of cell cycle PMID:8681378
GO:0097193 intrinsic apoptotic signaling pathway PMID:8681378
located_inGO:0019005 SCF ubiquitin ligase complex PMID:10713156; PMID:10921923; PMID:17098746