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Protein Ontology report - smad2 isoform Long phosphorylated and ubiquitinated 1

PR:000000654 - http://purl.obolibrary.org/obo/PR_000000654

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000000654

PRO name

smad2 isoform Long phosphorylated and ubiquitinated 1

Synonyms

PRO-Short-label:

EXACT:

SMAD2/iso:Long/PhosUbiq:1

Definition

"A smad2 isoform Long phosphorylated and ubiquitinated form that has been phosphorylated by TGF-beta receptor activation and further ubiquitinated by NEDD4L. This form is targeted for proteosomal degradation. Example: UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141]

PRO Category

modification

Parent

PR:000000573 smad2 isoform Long phosphorylated and ubiquitinated form

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	1	Organism-Modification	1

Term Hierarchy
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DAG:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

modification

PR:000000654 smad2 isoform Long phosphorylated and ubiquitinated 1, SMAD2/iso:Long/PhosUbiq:1

organism-modification

PR:000036555 smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse), mSMAD2/iso:Long/PhosUbiq:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036555 mSMAD2/iso:Long/PhosUbiq:1 UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046\|MOD:01148 "A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046\|MOD:01148." [PMID:15496141, PRO:CNA]	acts_upstream_of_or_within	GO:0007165 signal transduction	PMID:15496141
	enables	NOT GO:0003713 transcription coactivator activity	PMID:15496141