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RACE-PRO
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Protein Ontology report - cftr isoform 1 phosphorylated 1
PR:000001051 -
http://purl.obolibrary.org/obo/PR_000001051
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000001051
PRO name
cftr isoform 1 phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
CFTR/iso:1/Phos:1
Other
:
RELATED:
cftr PKA phosphorylated form
Definition
"A cftr isoform 1 phosphorylated form in which the phosphorylation occurs at multiple Ser and/or Thr residues within the PKA consensus sites R[RK]x [ST] located within the regulatory domain (R-domain). Example:
UniProtKB:P13569-1
, Ser-737/Ser-768/Ser-795/Ser-813,
MOD:00046
." [
PMID:1377674
,
PMID:14602047
]
Comment
Note: This is an active form.
PRO Category
modification
Parent
PR:000001050
cftr isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000001051
cftr isoform 1 phosphorylated 1, CFTR/iso:1/Phos:1
organism-modification
PR:000036594
cftr isoform 1 phosphorylated 1 (human), hCFTR/iso:1/Phos:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036594
hCFTR/iso:1/Phos:1
UniProtKB:P13569-1, Ser-737/Ser-768/Ser-795/Ser-813, MOD:00046
"A cftr isoform 1 phosphorylated 1 in human. Example: UniProtKB:P13569-1, Ser-737/Ser-768/Ser-795/Ser-813, MOD:00046." [PMID:1377674, PMID:14602047, PMID:1716180, PRO:CNA]
enables
GO:0005260
intracellularly ATP-gated chloride channel activity
PMID:1716180
GO:0005260
intracellularly ATP-gated chloride channel activity
PMID:1716180
