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RACE-PRO
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Documentation
Protein Ontology report - cytokine receptor common subunit beta
PR:000001339 -
http://purl.obolibrary.org/obo/PR_000001339
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000001339
PRO name
cytokine receptor common subunit beta
Synonyms
PRO-Short-label
:
EXACT:
CSF2RB
Gene-based
:
RELATED:
IL3RB | IL5RB
Other
:
EXACT:
CD131 | CDw131 | cytokine receptor common beta chain | GM-CSF/IL-3/IL-5 receptor common beta subunit
RELATED:
Aic2b | Csf2rb1 | Il3rb1
Definition
"A protein that is a translation product of the human CSF2RB gene or a 1:1 ortholog thereof. This gene encodes the receptor beta chain shared by high-affinity IL5, IL3, and GM-CSF receptors. In mouse, there is also a closely related gene that encodes an IL3-specific beta chain." [PRO:WCB,
UniProtKB:P26954
]
PRO Category
gene
Parent
PR:000000001
protein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
1
Sequence
0
Organism-Sequence
2
Modification
0
Organism-Modification
7
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
IUPHARobj:2306
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
gene
PR:000001339
cytokine receptor common subunit beta, CSF2RB
organism-gene
PR:P32927
cytokine receptor common subunit beta (human), hCSF2RB
organism-sequence
PR:P32927-1
cytokine receptor common subunit beta isoform 1 (human), hCSF2RB/iso:1
organism-modification
PR:000044814
cytokine receptor common subunit beta isoform 1 phosphorylated 1 (human), hCSF2RB/iso:1/Phos:1
Yes
organism-sequence
PR:P32927-2
cytokine receptor common subunit beta isoform h2 (human), hCSF2RB/iso:h2
organism-modification
PR:000047082
cytokine receptor common subunit beta, signal peptide removed form (human), hCSF2RB/SigPep-
organism-modification
PR:000047083
cytokine receptor common subunit beta, signal peptide removed phosphorylated 1 (human), hCSF2RB/SigPep-/Phos:1
organism-modification
PR:000047084
cytokine receptor common subunit beta, signal peptide removed phosphorylated 2 (human), hCSF2RB/SigPep-/Phos:2
organism-modification
PR:000047085
cytokine receptor common subunit beta, signal peptide removed phosphorylated 3 (human), hCSF2RB/SigPep-/Phos:3
organism-modification
PR:000063664
cytokine receptor common subunit beta sequence variant S271L, signal peptide removed form (human), hCSF2RB/var:S271L/SigPep-
organism-modification
PR:000078162
cytokine receptor common subunit beta methylated 1 (human), hCSF2RB/Me:1
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000044814
hCSF2RB/iso:1/Phos:1
UniProtKB:P32927-1, Ser-601, MOD:00046 | Bc phosphorylated 1 (human) | CSF2RB isoform 1 phosphorylated 1 (human) | beta c phosphorylated 1 (human)
"A cytokine receptor common subunit beta isoform 1 (human) that has been phosphorylated in the Ser residue within the 14-3-3 recognition motif RSXSXP. UniProtKB:P32927-1, Ser-601, MOD:00046." [PMID:10477722, PMID:10949031, PRO:CNA]
enables
GO:0071889
14-3-3 protein binding
with
PR:P63104
hYWHAZ
PMID:10477722