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RACE-PRO
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Protein Ontology report - interleukin-10
PR:000001471 -
http://purl.obolibrary.org/obo/PR_000001471
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000001471
PRO name
interleukin-10
Synonyms
PRO-Short-label
:
EXACT:
IL10
Other
:
EXACT:
CSIF | cytokine synthesis inhibitory factor | IL-10
Definition
"A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof." [PRO:JAN]
Comment
Note: Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds.
PRO Category
gene
Parent
PR:000001335
class 2 cytokine, IL-10 type
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
4
Sequence
1
Organism-Sequence
3
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
gene
PR:000001471
interleukin-10, IL10
organism-gene
PR:P18893
interleukin-10 (mouse), mIL10
organism-sequence
PR:P18893-1
interleukin-10 isoform 1 (mouse), mIL10/iso:1
organism-gene
PR:P22301
interleukin-10 (human), hIL10
organism-sequence
PR:P22301-1
interleukin-10 isoform 1 (human), hIL10/iso:1
organism-modification
PR:000063204
interleukin-10, signal peptide removed form (human), hIL10/SigPep-
organism-gene
PR:P29456
interleukin-10 (rat), rIL10
organism-sequence
PR:P29456-1
interleukin-10 isoform 1 (rat), rIL10/iso:1
organism-gene
PR:Q6A2H4
interleukin-10 (chicken), chick-IL10
sequence
PR:000039066
interleukin-10 isoform 1, IL10/iso:1
organism-sequence
PR:P18893-1
interleukin-10 isoform 1 (mouse), mIL10/iso:1
organism-sequence
PR:P22301-1
interleukin-10 isoform 1 (human), hIL10/iso:1
organism-sequence
PR:P29456-1
interleukin-10 isoform 1 (rat), rIL10/iso:1
modification
PR:000018500
interleukin-10, signal peptide removed form, IL10/SigPep-