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Protein Ontology report - inhibitor of nuclear factor kappa-B kinase subunit alpha
PR:000001775 - http://purl.obolibrary.org/obo/PR_000001775
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001775   
  PRO nameinhibitor of nuclear factor kappa-B kinase subunit alpha 
  Synonyms
PRO-Short-label: EXACT:CHUK
Gene-based: RELATED:IKKA | TCF16
Other: EXACT:conserved helix-loop-helix ubiquitous kinase | I-kappa-B kinase 1 | I-kappa-B kinase alpha | IkappaB kinase | IkBKA | IKK-A | IKK-alpha | IKK1 | NFKBIKA | nuclear factor NF-kappa-B inhibitor kinase alpha | TCF-16 | transcription factor 16
  Definition"An inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits that is a translation product of the human CHUK gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001774 inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification1                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1989
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001775 inhibitor of nuclear factor kappa-B kinase subunit alpha, CHUK

organism-gene


PR:O15111 inhibitor of nuclear factor kappa-B kinase subunit alpha (human), hCHUK

Yes
organism-sequence


PR:O15111-1 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 (human), hCHUK/iso:1

organism-modification


PR:000026823 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 (human), hCHUK/iso:1/Phos:1

Yes
organism-modification


PR:000045576 inhibitor of nuclear factor kappa-B kinase subunit alpha phosphorylated 2 (human), hCHUK/Phos:2

organism-modification


PR:000062311 inhibitor of nuclear factor kappa-B kinase subunit alpha phosphorylated 1 (human), hCHUK/Phos:1

organism-modification


PR:000065276 inhibitor of nuclear factor kappa-B kinase subunit alpha methylated 1 (human), hCHUK/Me:1

organism-modification


PR:000085410 inhibitor of nuclear factor kappa-B kinase subunit alpha deaminated 1 (human), hCHUK/Deam:1

organism-gene


PR:Q4G3H4 inhibitor of nuclear factor kappa-B kinase subunit alpha (zebrafish), z-CHUK

organism-gene


PR:Q5ZJB4 inhibitor of nuclear factor kappa-B kinase subunit alpha (chicken), chick-CHUK

organism-gene


PR:Q60680 inhibitor of nuclear factor kappa-B kinase subunit alpha (mouse), mCHUK

organism-sequence


PR:Q60680-1 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 (mouse), mCHUK/iso:1

Yes
organism-modification


PR:000036121 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 (mouse), mCHUK/iso:1/Phos:1

Yes
organism-sequence


PR:Q60680-2 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform m2 (mouse), mCHUK/iso:m2

organism-sequence


PR:Q60680-3 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform m3 (mouse), mCHUK/iso:m3

sequence


PR:000026820 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1, CHUK/iso:1

organism-sequence


PR:O15111-1 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 (human), hCHUK/iso:1

organism-modification


PR:000026823 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 (human), hCHUK/iso:1/Phos:1

Yes
organism-sequence


PR:Q60680-1 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 (mouse), mCHUK/iso:1

Yes
organism-modification


PR:000036121 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 (mouse), mCHUK/iso:1/Phos:1

Yes
modification


PR:000026822 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1, CHUK/iso:1/Phos:1

organism-modification


PR:000026823 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 (human), hCHUK/iso:1/Phos:1

Yes
organism-modification


PR:000036121 inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 phosphorylated 1 (mouse), mCHUK/iso:1/Phos:1

Yes
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CHUK forms found in complexes   

CHUK Component
 Complexes
PR:000026823 hCHUK/iso:1/Phos:1 PR:000035833 activated IkappaB kinase complex (human)
PR:000036121 mCHUK/iso:1/Phos:1 PR:000036119 activated IkappaB kinase complex (mouse)
PR:O15111 hCHUK PR:000026457 IkappaB kinase complex (human)
PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human)
PR:Q60680ZDASHZ1 mCHUK/iso:1 PR:000036118 IkappaB kinase complex (mouse)