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Protein Ontology report - interferon regulatory factor 7
PR:000002049 - http://purl.obolibrary.org/obo/PR_000002049
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002049   
  PRO nameinterferon regulatory factor 7 
  Synonyms
PRO-Short-label: EXACT:IRF7
Other: EXACT:IRF-7
  Definition"An interferon regulatory factor 3-9 that is a translation product of the human IRF7 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001863 interferon regulatory factor 3-9
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification4                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002049 interferon regulatory factor 7, IRF7

organism-gene


PR:P70434 interferon regulatory factor 7 (mouse), mIRF7

organism-gene


PR:Q92985 interferon regulatory factor 7 (human), hIRF7

organism-sequence


PR:Q92985-1 interferon regulatory factor 7 isoform A (human), hIRF7/iso:A

organism-modification


PR:000027082 interferon regulatory factor 7 isoform 1 phosphorylated 1 (human), hIRF7/iso:1/Phos:1

Yes
organism-modification


PR:000037791 interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human), hIRF7/iso:1/UnPhos:1
Yes
organism-sequence


PR:Q92985-2 interferon regulatory factor 7 isoform B (human), hIRF7/iso:B

organism-sequence


PR:Q92985-3 interferon regulatory factor 7 isoform C (human), hIRF7/iso:C

organism-sequence


PR:Q92985-4 interferon regulatory factor 7 isoform D (human), hIRF7/iso:D

organism-modification


PR:000028704 interferon regulatory factor 7 unmodified form (human), hIRF7/UnMod

Yes
organism-modification


PR:000048049 interferon regulatory factor 7 phosphorylated 1 (human), hIRF7/Phos:1

organism-modification


PR:000048050 interferon regulatory factor 7 ubiquitinated form (human), hIRF7/UbiqLys+

organism-modification


PR:000066902 interferon regulatory factor 7 cysteinylated 1 (human), hIRF7/Cyst:1

organism-modification


PR:000078397 interferon regulatory factor 7 methylated 1 (human), hIRF7/Me:1

organism-modification


PR:000080104 interferon regulatory factor 7 cysteinylated 2 (human), hIRF7/Cyst:2

organism-modification


PR:000080211 interferon regulatory factor 7 methylated 2 (human), hIRF7/Me:2

sequence


PR:000003261 interferon regulatory factor 7 isoform 1, IRF7/iso:1

organism-sequence


PR:Q92985-1 interferon regulatory factor 7 isoform A (human), hIRF7/iso:A

organism-modification


PR:000027082 interferon regulatory factor 7 isoform 1 phosphorylated 1 (human), hIRF7/iso:1/Phos:1

Yes
organism-modification


PR:000037791 interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human), hIRF7/iso:1/UnPhos:1
Yes
modification


PR:000003280 interferon regulatory factor 7 isoform 1 phosphorylated form, IRF7/iso:1/PhosRes+

modification


PR:000003281 interferon regulatory factor 7 isoform 1 phosphorylated 1, IRF7/iso:1/Phos:1

organism-modification


PR:000027082 interferon regulatory factor 7 isoform 1 phosphorylated 1 (human), hIRF7/iso:1/Phos:1

Yes
modification


PR:000037790 interferon regulatory factor 7 isoform 1 unphosphorylated 1, IRF7/iso:1/UnPhos:1

organism-modification


PR:000037791 interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human), hIRF7/iso:1/UnPhos:1
Yes
modification


PR:000028703 interferon regulatory factor 7 unmodified form, IRF7/UnMod

organism-modification


PR:000028704 interferon regulatory factor 7 unmodified form (human), hIRF7/UnMod

Yes
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IRF7 forms found in complexes   

IRF7 Component
 Complexes
PR:000027082 hIRF7/iso:1/Phos:1 PR:000027084 IRF3-P:IRF7-P complex (human)
PR:000027086 IRF7-P:IRF7-P complex (human)
PR:000028704 hIRF7/UnMod PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037791 hIRF7/iso:1/UnPhos:1
UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291 | IRF-7 unphosphorylated (human)
"An interferon regulatory factor 7 isoform 1 unphosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291." [PMID:10893229, PMID:14517278, PRO:CNA]		 located_inGO:0005737 cytoplasm Reactome:REACT_21735