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Protein Ontology report - zinc finger protein Helios
PR:000002172 - http://purl.obolibrary.org/obo/PR_000002172
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002172   
  PRO namezinc finger protein Helios 
  Synonyms
PRO-Short-label: EXACT:IKZF2
Gene-based: RELATED:HELIOS | Zfpn1a2 | ZNFN1A2
Other: EXACT:Ikaros family zinc finger protein 2
  Definition"An Ikaros-like zinc finger transcription factor that is a translation product of the human IKZF2 gene or a 1:1 ortholog thereof." [PRO:HJD] 
  PRO Categorygene 
  ParentPR:000002986 Ikaros-like zinc finger transcription factor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 12                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002172 zinc finger protein Helios, IKZF2

organism-gene


PR:H2L008 zinc finger protein ztf-16 (worm), IKZF2 (worm)

organism-sequence


PR:H2L008-1 zinc finger protein ztf-16 isoform b (worm), IKZF2/iso:b (worm)

organism-sequence


PR:H2L008-2 zinc finger protein ztf-16 isoform a (worm), IKZF2/iso:a (worm)

organism-gene


PR:P81183 zinc finger protein Helios (mouse), mIKZF2
Yes
organism-sequence


PR:P81183-1 zinc finger protein Helios isoform B (mouse), mIKZF2/iso:B
Yes
organism-sequence


PR:P81183-2 zinc finger protein Helios isoform A (mouse), mIKZF2/iso:A
Yes
organism-gene


PR:Q9UKS7 zinc finger protein Helios (human), hIKZF2

organism-sequence


PR:Q9UKS7-1 zinc finger protein Helios isoform 1 (human), hIKZF2/iso:1

organism-sequence


PR:Q9UKS7-2 zinc finger protein Helios isoform 2 (human), hIKZF2/iso:2

organism-sequence


PR:Q9UKS7-3 zinc finger protein Helios isoform h3 (human), hIKZF2/iso:h3

organism-sequence


PR:Q9UKS7-4 zinc finger protein Helios isoform h4 (human), hIKZF2/iso:h4

organism-sequence


PR:Q9UKS7-5 zinc finger protein Helios isoform h5 (human), hIKZF2/iso:h5

organism-sequence


PR:Q9UKS7-6 zinc finger protein Helios isoform h6 (human), hIKZF2/iso:h6

organism-sequence


PR:Q9UKS7-7 zinc finger protein Helios isoform h7 (human), hIKZF2/iso:h7

organism-sequence


PR:Q9UKS7-8 zinc finger protein Helios isoform h8 (human), hIKZF2/iso:h8

organism-modification


PR:000081230 zinc finger protein Helios methylated 1 (human), hIKZF2/Me:1

organism-modification


PR:000081486 zinc finger protein Helios phosphorylated 1 (human), hIKZF2/Phos:1

sequence


PR:000002173 zinc finger protein Helios isoform 1, IKZF2/iso:1
Yes
organism-sequence


PR:P81183-1 zinc finger protein Helios isoform B (mouse), mIKZF2/iso:B
Yes
organism-sequence


PR:Q9UKS7-1 zinc finger protein Helios isoform 1 (human), hIKZF2/iso:1

sequence


PR:000002174 zinc finger protein Helios isoform 2, IKZF2/iso:2
Yes
organism-sequence


PR:P81183-2 zinc finger protein Helios isoform A (mouse), mIKZF2/iso:A
Yes
organism-sequence


PR:Q9UKS7-2 zinc finger protein Helios isoform 2 (human), hIKZF2/iso:2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000002173 IKZF2/iso:1
zinc finger protein Helios isoform B
"A zinc finger protein Helios that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P81183-1 or a 1:1 ortholog thereof." [PRO:HJD]		 enablesGO:0046982 protein heterodimerization activity with PR:O08900|PR:Q03267-1 MGI:1203354; PMID:9560339
PR:000002174 IKZF2/iso:2
zinc finger protein Helios isoform A
"A zinc finger protein Helios that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P81183-2 or a 1:1 ortholog thereof." [PRO:HJD]		 enablesGO:0046982 protein heterodimerization activity with PR:P81183-1|PR:P81183-2 MGI:1203354; PMID:9560339
PR:P81183 mIKZF2
Helios | Ikzf2 | Zfpn1a2 | Znfn1a2 | Ikaros family zinc finger protein 2 (mouse)
"A zinc finger protein Helios that is encoded in the genome of mouse." [OMA:P81183, PRO:DNx]		 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II PMID:9560339
enablesGO:0042803 protein homodimerization activity with PR:P81183 Helios PMID:9560339
PR:P81183-1 mIKZF2/iso:B

"A zinc finger protein Helios isoform 1 that is encoded in the genome of mouse." [PRO:HJD]		 enablesGO:0046982 protein heterodimerization activity with PR:O08900 Ikaros family zinc finger protein 3 (mouse) MGI:1203354; PMID:9560339
GO:0046982 protein heterodimerization activity with PR:O08900-1|PR:Q03267-1 MGI:1203354; PMID:9560339
GO:0046982 protein heterodimerization activity with PR:Q03267-1 MGI:1203354; PMID:9560339
located_inGO:0005634 nucleus PMID:9560339
PR:P81183-2 mIKZF2/iso:A

"A zinc finger protein Helios isoform 2 that is encoded in the genome of mouse." [PRO:HJD]		 enablesGO:0046982 protein heterodimerization activity with PR:O08900-1|PR:Q03267-1 MGI:1203354; PMID:9560339
GO:0046982 protein heterodimerization activity with PR:P81183-1 MGI:1203354; PMID:9560339
GO:0046982 protein heterodimerization activity with PR:P81183-2 MGI:1203354; PMID:9560339
located_inGO:0005634 nucleus PMID:9560339