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Protein Ontology report - TNF receptor-associated factor 6
PR:000002292 - http://purl.obolibrary.org/obo/PR_000002292
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002292   
  PRO nameTNF receptor-associated factor 6 
  Synonyms
PRO-Short-label: EXACT:TRAF6
Gene-based: RELATED:RNF85
Other: EXACT:E3 ubiquitin-protein ligase TRAF6 | interleukin-1 signal transducer | RING finger protein 85 | RING-type E3 ubiquitin transferase TRAF6
  Definition"A TNF receptor-associated factor that is a translation product of the human TRAF6 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000002191
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 3                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002292 TNF receptor-associated factor 6, TRAF6

organism-gene


PR:B5DF45 TNF receptor-associated factor 6 (rat), rTRAF6

organism-gene


PR:P70196 TNF receptor-associated factor 6 (mouse), mTRAF6

Yes
organism-sequence


PR:P70196-1 TNF receptor-associated factor 6 isoform 1 (mouse), mTRAF6/iso:1

organism-modification


PR:000035712 TNF receptor-associated factor 6 isoform 1 K63-polyubiquitinated 1 (mouse), mTRAF6/iso:1/K63polyUbiq:1

organism-sequence


PR:P70196-2 TNF receptor-associated factor 6 isoform 2 (mouse), mTRAF6/iso:2

organism-gene


PR:Q6IWL4 TNF receptor-associated factor 6 (zebrafish), z-TRAF6

organism-gene


PR:Q9Y4K3 TNF receptor-associated factor 6 (human), hTRAF6

Yes
organism-sequence


PR:Q9Y4K3-1 TNF receptor-associated factor 6 isoform 1 (human), hTRAF6/iso:1

organism-modification


PR:000035714 TNF receptor-associated factor 6 K63-polyubiquitinated 1 (human), hTRAF6/K63polyUbiq:1
Yes
Yes
organism-modification


PR:000064696 TNF receptor-associated factor 6 ubiquitinated form (human), hTRAF6/UbiqLys+

organism-modification


PR:000066371 TNF receptor-associated factor 6 cysteinylated 1 (human), hTRAF6/Cyst:1

sequence


PR:000002381 TNF receptor-associated factor 6 isoform 1, TRAF6/iso:1

organism-sequence


PR:P70196-1 TNF receptor-associated factor 6 isoform 1 (mouse), mTRAF6/iso:1

organism-modification


PR:000035712 TNF receptor-associated factor 6 isoform 1 K63-polyubiquitinated 1 (mouse), mTRAF6/iso:1/K63polyUbiq:1

organism-sequence


PR:Q9Y4K3-1 TNF receptor-associated factor 6 isoform 1 (human), hTRAF6/iso:1

modification


PR:000003138 TNF receptor-associated factor 6 isoform 1 ubiquitinated form, TRAF6/iso:1/UbiqLys+

modification


PR:000003139 TNF receptor-associated factor 6 isoform 1 K63-polyubiquitinated 1, TRAF6/iso:1/K63polyUbiq:1

organism-modification


PR:000035712 TNF receptor-associated factor 6 isoform 1 K63-polyubiquitinated 1 (mouse), mTRAF6/iso:1/K63polyUbiq:1

sequence


PR:000002382 TNF receptor-associated factor 6 isoform 2, TRAF6/iso:2

organism-sequence


PR:P70196-2 TNF receptor-associated factor 6 isoform 2 (mouse), mTRAF6/iso:2

modification


PR:000035713 TNF receptor-associated factor 6 K63-polyubiquitinated 1, TRAF6/K63polyUbiq:1

organism-modification


PR:000035714 TNF receptor-associated factor 6 K63-polyubiquitinated 1 (human), hTRAF6/K63polyUbiq:1
Yes
Yes
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TRAF6 forms found in complexes   

TRAF6 Component
 Complexes
PR:000035714 hTRAF6/K63polyUbiq:1 PR:000035715^P000035734^P000035738^P000035740^P000037338^P000037340^P000037342
PR:P70196 mTRAF6 PR:000035710^P000036101^P000036105^P000036109^P000036111^P000036114^P000036117^P000037471
PR:Q9Y4K3 hTRAF6 PR:000028680^P000037344
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035714
hTRAF6/K63polyUbiq:1
UniProtKB:Q9Y4K3, Lys-124, PR:000044772 | K63-pUb-TRAF6		 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894