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Protein Ontology report - ezrin isoform 1 phosphorylated 6
PR:000003042 -
http://purl.obolibrary.org/obo/PR_000003042
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000003042
PRO name
ezrin isoform 1 phosphorylated 6
Synonyms
PRO-Short-label
:
EXACT:
EZR/iso:1/Phos:6
Definition
"An ezrin isoform 1 phosphorylated form in which the phosphorylation occurs at either the C-terminal Thr (Thr-567 in human), through kinases such as Rho-kinase, or the N-terminal tyrosine residue (Tyr-354 in human). Example:
UniProtKB:P15311-1
, Tyr-354,
MOD:00048
|Thr-567,
MOD:00047
." [
PMID:18852256
, PRO:AL]
PRO Category
modification
Parent
PR:000001033
ezrin isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000003042
ezrin isoform 1 phosphorylated 6, EZR/iso:1/Phos:6
organism-modification
PR:000036625
ezrin isoform 1 phosphorylated 6 (human), hEZR/iso:1/Phos:6
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036625
hEZR/iso:1/Phos:6
UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047
"An ezrin isoform 1 phosphorylated 6 in human. UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047." [PMID:18852256, PRO:AL]
enables
GO:0003779
actin binding
PMID:18852256
located_in
GO:0002102
podosome
PMID:18852256
GO:0005886
plasma membrane
PMID:18852256
