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Protein Ontology report - tyrosine-protein kinase SYK
PR:000003065 - http://purl.obolibrary.org/obo/PR_000003065
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003065   
  PRO nametyrosine-protein kinase SYK 
  Synonyms
PRO-Short-label: EXACT:SYK
Other: EXACT:spleen tyrosine kinase
  Definition"A SYK/ZAP-70 family tyrosine-protein kinase that is a translation product of the human SYK gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000003063
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification2                                                  Organism-Modification 13                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2230
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003065 tyrosine-protein kinase SYK, SYK

organism-gene


PR:F1N9Y5 tyrosine-protein kinase SYK (chicken), chick-SYK

organism-gene


PR:P43405 tyrosine-protein kinase SYK (human), hSYK

organism-sequence


PR:P43405-1 tyrosine-protein kinase SYK isoform Long (human), hSYK/iso:Long

organism-sequence


PR:P43405-2 tyrosine-protein kinase SYK isoform Short (human), hSYK/iso:Short

organism-modification


PR:000049392 tyrosine-protein kinase SYK phosphotyrosine form (human), hSYK/PhosTyr+

organism-modification


PR:000026221 tyrosine-protein kinase SYK phosphorylated 2 (human), hSYK/Phos:2

organism-modification


PR:000049391 tyrosine-protein kinase SYK phosphorylated 3 (human), hSYK/Phos:3

organism-modification


PR:000070011 tyrosine-protein kinase SYK cysteinylated 1 (human), hSYK/Cyst:1

organism-modification


PR:000071958 tyrosine-protein kinase SYK deaminated 1 (human), hSYK/Deam:1

organism-gene


PR:P48025 tyrosine-protein kinase SYK (mouse), mSYK

organism-sequence


PR:P48025-1 tyrosine-protein kinase SYK isoform 1 (mouse), mSYK/iso:1

organism-modification


PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse), mSYK/iso:1/Phos:1
Yes
organism-modification


PR:000049791 tyrosine-protein kinase SYK isoform 1 phosphorylated 2 (mouse), mSYK/iso:1/Phos:2

organism-modification


PR:000049792 tyrosine-protein kinase SYK isoform 1 unphosphorylated 2 (mouse), mSYK/iso:1/UnPhos:2

organism-modification


PR:000049793 tyrosine-protein kinase SYK isoform 1 phosphorylated 3 (mouse), mSYK/iso:1/Phos:3

organism-modification


PR:000049794 tyrosine-protein kinase SYK isoform 1 unphosphorylated 3 (mouse), mSYK/iso:1/UnPhos:3

organism-modification


PR:000049795 tyrosine-protein kinase SYK isoform 1 phosphorylated 4 (mouse), mSYK/iso:1/Phos:4

organism-modification


PR:000049796 tyrosine-protein kinase SYK isoform 1 phosphorylated 5 (mouse), mSYK/iso:1/Phos:5

organism-modification


PR:000049800 tyrosine-protein kinase SYK isoform 1 phosphorylated 6 (mouse), mSYK/iso:1/Phos:6

organism-gene


PR:Q64725 tyrosine-protein kinase SYK (rat), rSYK

organism-sequence


PR:Q64725-1 tyrosine-protein kinase SYK isoform SykB (rat), rSYK/iso:SykB

organism-sequence


PR:Q64725-2 tyrosine-protein kinase SYK isoform SykA (rat), rSYK/iso:SykA

sequence


PR:000025832 tyrosine-protein kinase SYK isoform 1, SYK/iso:1

organism-sequence


PR:P43405-1 tyrosine-protein kinase SYK isoform Long (human), hSYK/iso:Long

organism-sequence


PR:P48025-1 tyrosine-protein kinase SYK isoform 1 (mouse), mSYK/iso:1

organism-modification


PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse), mSYK/iso:1/Phos:1
Yes
organism-modification


PR:000049791 tyrosine-protein kinase SYK isoform 1 phosphorylated 2 (mouse), mSYK/iso:1/Phos:2

organism-modification


PR:000049792 tyrosine-protein kinase SYK isoform 1 unphosphorylated 2 (mouse), mSYK/iso:1/UnPhos:2

organism-modification


PR:000049793 tyrosine-protein kinase SYK isoform 1 phosphorylated 3 (mouse), mSYK/iso:1/Phos:3

organism-modification


PR:000049794 tyrosine-protein kinase SYK isoform 1 unphosphorylated 3 (mouse), mSYK/iso:1/UnPhos:3

organism-modification


PR:000049795 tyrosine-protein kinase SYK isoform 1 phosphorylated 4 (mouse), mSYK/iso:1/Phos:4

organism-modification


PR:000049796 tyrosine-protein kinase SYK isoform 1 phosphorylated 5 (mouse), mSYK/iso:1/Phos:5

organism-modification


PR:000049800 tyrosine-protein kinase SYK isoform 1 phosphorylated 6 (mouse), mSYK/iso:1/Phos:6

modification


PR:000025833 tyrosine-protein kinase SYK isoform 1 phosphorylated 1, SYK/iso:1/Phos:1

organism-modification


PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse), mSYK/iso:1/Phos:1
Yes
modification


PR:000026193 tyrosine-protein kinase SYK phosphorylated 2, SYK/Phos:2

organism-modification


PR:000026221 tyrosine-protein kinase SYK phosphorylated 2 (human), hSYK/Phos:2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025834
mSYK/iso:1/Phos:1
UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048		 acts_upstream_of_or_withinGO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis PMID:15536084
enablesGO:0019901 protein kinase binding with PR:P09769 FGR PMID:15536084
GO:0031625 ubiquitin protein ligase binding PMID:15536084
GO:0043548 phosphatidylinositol 3-kinase binding PMID:15536084