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Protein Ontology report - leukocyte granule-associated proteinase
PR:000003505 - http://purl.obolibrary.org/obo/PR_000003505
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000003505   
  PRO nameleukocyte granule-associated proteinase 
  Definition"A trypsin that is a serine protease of the granules from mast cells, cytotoxic T lymphocytes and/or natural killer cells. Leukocyte granule-associated proteinase is a component of the immune system that protect higher organisms against viral infection and cellular transformation. Members of this class have features that are strongly conserved including: consensus sequences at their N-termini and around the three catalytic residues, activation from zymogenic forms, and conserved disulphide bridges." [PMID:11790262, PMID:7952649, PMID:8929545
  PRO Categoryfamily 
  ParentPR:000027795
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene10                                                  Organism-Gene 15                                        
         Sequence10                                                  Organism-Sequence 13                                        
         Modification23                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
family



PR:000003505 leukocyte granule-associated proteinase, GZMA/iso:1


gene



PR:000003472 granzyme K, GZMK


organism-gene



PR:O35205 granzyme K (mouse), mGZMK


organism-gene



PR:P49863 granzyme K (human), hGZMK


organism-sequence



PR:P49863-1 granzyme K isoform 1 (human), hGZMK/iso:1


organism-modification



PR:000068076 granzyme K phosphorylated 1 (human), hGZMK/Phos:1


organism-gene



PR:P49864 granzyme K (rat), rGZMK


sequence



PR:000003473 granzyme K isoform 1, GZMK/iso:1


organism-sequence



PR:P49863-1 granzyme K isoform 1 (human), hGZMK/iso:1


modification



PR:000018820 granzyme K proteolytic cleavage product, GZMK/ClvPrd


gene



PR:000003475 granzyme D, Gzmd


organism-gene



PR:P11033 granzyme D (mouse), mGzmd


organism-sequence



PR:P11033-1 granzyme D isoform 1 (mouse), mGzmd/iso:1


sequence



PR:000003476 granzyme D isoform 1, Gzmd/iso:1


organism-sequence



PR:P11033-1 granzyme D isoform 1 (mouse), mGzmd/iso:1


modification



PR:000026635 granzyme D isoform 1, signal peptide removed form, Gzmd/iso:1/SigPep-


modification



PR:000018822 granzyme D, signal peptide removed form, Gzmd/SigPep-


modification



PR:000026635 granzyme D isoform 1, signal peptide removed form, Gzmd/iso:1/SigPep-


modification



PR:000018823 granzyme D proteolytic cleavage product, Gzmd/ClvPrd


gene



PR:000003478 granzyme G, Gzmg


organism-gene



PR:P13366 granzyme G (mouse), mGzmg


organism-sequence



PR:P13366-1 granzyme G isoform 1 (mouse), mGzmg/iso:1


sequence



PR:000003479 granzyme G isoform 1, Gzmg/iso:1


organism-sequence



PR:P13366-1 granzyme G isoform 1 (mouse), mGzmg/iso:1


modification



PR:000026722 granzyme G isoform 1, signal peptide removed form, Gzmg/iso:1/SigPep-


modification



PR:000018825 granzyme G, signal peptide removed form, Gzmg/SigPep-


modification



PR:000026722 granzyme G isoform 1, signal peptide removed form, Gzmg/iso:1/SigPep-


modification



PR:000018826 granzyme G proteolytic cleavage product, Gzmg/ClvPrd


gene



PR:000003481 granzyme M, GZMM


organism-gene



PR:P51124 granzyme M (human), hGZMM


organism-sequence



PR:P51124-1 granzyme M isoform 1 (human), hGZMM/iso:1


sequence



PR:000003482 granzyme M isoform 1, GZMM/iso:1


organism-sequence



PR:P51124-1 granzyme M isoform 1 (human), hGZMM/iso:1


gene



PR:000003484 granzyme E, Gzme


organism-gene



PR:P08884 granzyme E (mouse), mGzme


organism-sequence



PR:P08884-1 granzyme E isoform 1 (mouse), mGzme/iso:1


sequence



PR:000003485 granzyme E isoform 1, Gzme/iso:1


organism-sequence



PR:P08884-1 granzyme E isoform 1 (mouse), mGzme/iso:1


modification



PR:000026595 granzyme E isoform 1, signal peptide removed form, Gzme/iso:1/SigPep-


modification



PR:000018828 granzyme E, signal peptide removed form, Gzme/SigPep-


modification



PR:000026595 granzyme E isoform 1, signal peptide removed form, Gzme/iso:1/SigPep-


modification



PR:000018829 granzyme E proteolytic cleavage product, Gzme/ClvPrd


gene



PR:000003487 granzyme C, Gzmc


organism-gene



PR:P08882 granzyme C (mouse), mGzmc


organism-sequence



PR:P08882-1 granzyme C isoform 1 (mouse), mGzmc/iso:1


organism-gene



PR:Q9VAQ2 CG11843, isoform A (fruit fly), fly-Gzmc


sequence



PR:000003488 granzyme C isoform 1, Gzmc/iso:1


organism-sequence



PR:P08882-1 granzyme C isoform 1 (mouse), mGzmc/iso:1


modification



PR:000026721 granzyme C isoform 1, signal peptide removed form, Gzmc/iso:1/SigPep-


modification



PR:000018831 granzyme C, signal peptide removed form, Gzmc/SigPep-


modification



PR:000026721 granzyme C isoform 1, signal peptide removed form, Gzmc/iso:1/SigPep-


modification



PR:000018832 granzyme C proteolytic cleavage product, Gzmc/ClvPrd


gene



PR:000003490 granzyme H, GZMH


organism-gene



PR:A8WIQ2 uncharacterized protein, si:ch211-165b19.4 translation product (zebrafish), z-GZMH


organism-gene



PR:P20718 granzyme H (human), hGZMH


organism-sequence



PR:P20718-1 granzyme H isoform 1 (human), hGZMH/iso:1


organism-sequence



PR:P20718-2 granzyme H isoform h2 (human), hGZMH/iso:h2


organism-sequence



PR:P20718-3 granzyme H isoform h3 (human), hGZMH/iso:h3


sequence



PR:000003491 granzyme H isoform 1, GZMH/iso:1


organism-sequence



PR:P20718-1 granzyme H isoform 1 (human), hGZMH/iso:1


modification



PR:000026717 granzyme H isoform 1, signal peptide removed form, GZMH/iso:1/SigPep-


modification



PR:000018834 granzyme H, signal peptide removed form, GZMH/SigPep-


modification



PR:000026717 granzyme H isoform 1, signal peptide removed form, GZMH/iso:1/SigPep-


modification



PR:000018835 granzyme H proteolytic cleavage product, GZMH/ClvPrd


gene



PR:000003493 granzyme F, Gzmf


organism-gene



PR:P08883 granzyme F (mouse), mGzmf


organism-sequence



PR:P08883-1 granzyme F isoform 1 (mouse), mGzmf/iso:1


sequence



PR:000003494 granzyme F isoform 1, Gzmf/iso:1


organism-sequence



PR:P08883-1 granzyme F isoform 1 (mouse), mGzmf/iso:1


modification



PR:000026685 granzyme F isoform 1, signal peptide removed form, Gzmf/iso:1/SigPep-


modification



PR:000018837 granzyme F, signal peptide removed form, Gzmf/SigPep-


modification



PR:000026685 granzyme F isoform 1, signal peptide removed form, Gzmf/iso:1/SigPep-


modification



PR:000018838 granzyme F proteolytic cleavage product, Gzmf/ClvPrd


gene



PR:000003499 granzyme B, GZMB


organism-gene



PR:P10144 granzyme B (human), hGZMB


organism-sequence



PR:P10144-1 granzyme B isoform 1 (human), hGZMB/iso:1


organism-modification



PR:000070174 granzyme B cysteinylated 1 (human), hGZMB/Cyst:1


organism-modification



PR:000083570 granzyme B cysteinylated 2 (human), hGZMB/Cyst:2


sequence



PR:000003500 granzyme B isoform 1, GZMB/iso:1


organism-sequence



PR:P10144-1 granzyme B isoform 1 (human), hGZMB/iso:1


organism-sequence



PR:P18291-1 granzyme B isoform 1 (rat), rGZMB/iso:1


modification



PR:000026713 granzyme B isoform 1, signal peptide removed form, GZMB/iso:1/SigPep-


modification



PR:000026712 granzyme B, signal peptide removed form, GZMB/SigPep-


modification



PR:000026713 granzyme B isoform 1, signal peptide removed form, GZMB/iso:1/SigPep-


gene



PR:000003502 granzyme A, GZMA


organism-gene



PR:P11032 granzyme A (mouse), mGZMA


organism-sequence



PR:P11032-1 granzyme A isoform HF1 (mouse), mGZMA/iso:HF1


organism-gene



PR:P12544 granzyme A (human), hGZMA


sequence



PR:000003503 granzyme A isoform 1, GZMA/iso:1


organism-sequence



PR:P11032-1 granzyme A isoform HF1 (mouse), mGZMA/iso:HF1


modification



PR:000026633 granzyme A isoform 1, signal peptide removed form, GZMA/iso:1/SigPep-


modification



PR:000026632 granzyme A, signal peptide removed form, GZMA/SigPep-


modification



PR:000026633 granzyme A isoform 1, signal peptide removed form, GZMA/iso:1/SigPep-