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Protein Ontology report - beclin-1
PR:000004719 - http://purl.obolibrary.org/obo/PR_000004719
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004719   
  PRO namebeclin-1 
  Synonyms
PRO-Short-label: EXACT:BECN1
Gene-based: RELATED:GT197
Other: EXACT:coiled-coil myosin-like BCL2-interacting protein | protein GT197
  Definition"A protein that is a translation product of the human BECN1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004719 beclin-1, BECN1

organism-gene


PR:F1RCP1 beclin-1 (zebrafish), z-BECN1

organism-gene


PR:O88597 beclin-1 (mouse), mBECN1

organism-sequence


PR:O88597-1 beclin-1 isoform 1 (mouse), mBECN1/iso:1

organism-modification


PR:000049934 beclin-1 phosphorylated 3 (mouse), mBECN1/Phos:3

organism-modification


PR:000049935 beclin-1 unphosphorylated 3 (mouse), mBECN1/UnPhos:3

organism-gene


PR:Q14457 beclin-1 (human), hBECN1

organism-sequence


PR:Q14457-1 beclin-1 isoform 1 (human), hBECN1/iso:1

organism-modification


PR:000027471 beclin-1 isoform 1 phosphorylated 1 (human), hBECN1/iso:1/Phos:1
Yes
organism-modification


PR:000027487 beclin-1 isoform 1 unmodified form (human), hBECN1/iso:1/UnMod

organism-modification


PR:000045927 beclin-1 phosphorylated 1 (human), hBECN1/Phos:1

organism-modification


PR:000046478 beclin-1 phosphorylated 2 (human), hBECN1/Phos:2

organism-modification


PR:000046479 beclin-1 ubiquitinated form (human), hBECN1/UbiqLys+

organism-modification


PR:000049932 beclin-1 phosphorylated 3 (human), hBECN1/Phos:3

organism-modification


PR:000049933 beclin-1 unphosphorylated 3 (human), hBECN1/UnPhos:3

organism-modification


PR:000084621 beclin-1 glutathionylated 1 (human), hBECN1/SGlt:1

organism-gene


PR:Q5ZKS6 beclin-1 (chicken), chick-BECN1

organism-gene


PR:Q91XJ1 beclin-1 (rat), rBECN1

organism-modification


PR:000049936 beclin-1 phosphorylated 3 (rat), rBECN1/Phos:3

organism-modification


PR:000049937 beclin-1 unphosphorylated 3 (rat), rBECN1/UnPhos:3

sequence


PR:000027468 beclin-1 isoform 1, BECN1/iso:1

organism-sequence


PR:O88597-1 beclin-1 isoform 1 (mouse), mBECN1/iso:1

organism-sequence


PR:Q14457-1 beclin-1 isoform 1 (human), hBECN1/iso:1

organism-modification


PR:000027471 beclin-1 isoform 1 phosphorylated 1 (human), hBECN1/iso:1/Phos:1
Yes
organism-modification


PR:000027487 beclin-1 isoform 1 unmodified form (human), hBECN1/iso:1/UnMod

modification


PR:000027470 beclin-1 isoform 1 phosphorylated 1, BECN1/iso:1/Phos:1

organism-modification


PR:000027471 beclin-1 isoform 1 phosphorylated 1 (human), hBECN1/iso:1/Phos:1
Yes
modification


PR:000027486 beclin-1 isoform 1 unmodified form, BECN1/iso:1/UnMod

organism-modification


PR:000027487 beclin-1 isoform 1 unmodified form (human), hBECN1/iso:1/UnMod

modification


PR:000049930 beclin-1 phosphorylated 3, BECN1/Phos:3

organism-modification


PR:000049932 beclin-1 phosphorylated 3 (human), hBECN1/Phos:3

organism-modification


PR:000049934 beclin-1 phosphorylated 3 (mouse), mBECN1/Phos:3

organism-modification


PR:000049936 beclin-1 phosphorylated 3 (rat), rBECN1/Phos:3

modification


PR:000049931 beclin-1 unphosphorylated 3, BECN1/UnPhos:3

organism-modification


PR:000049933 beclin-1 unphosphorylated 3 (human), hBECN1/UnPhos:3

organism-modification


PR:000049935 beclin-1 unphosphorylated 3 (mouse), mBECN1/UnPhos:3

organism-modification


PR:000049937 beclin-1 unphosphorylated 3 (rat), rBECN1/UnPhos:3

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027471 hBECN1/iso:1/Phos:1
UniProtKB:Q14457-1, Thr-119, MOD:00047
"A beclin-1 isoform 1 phosphorylated 1 in human. UniProtKB:Q14457-1, Thr-119, MOD:00047." [PMID:19180116, PMID:19395874, PRO:PD]		 acts_upstream_of_or_withinGO:0010508 positive regulation of autophagy PMID:19180116; PMID:19395874
enablesdecreased GO:0005515 protein binding with PR:P10415 BCL2 PMID:19180116
decreased GO:0005515 protein binding with PR:Q07817-1 PMID:19180116