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Protein Ontology report - sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1
PR:000022016 - http://purl.obolibrary.org/obo/PR_000022016
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000022016   
  PRO namesphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 
  Synonyms
PRO-Short-label: EXACT:DEGS2/iso:1
  Definition"A sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R2F2-1 or a 1:1 ortholog thereof." [PMID:11937514, PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000006414 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000022016 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1, DEGS2/iso:1
Yes
organism-sequence


PR:Q6QHC5-1 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 (human), hDEGS2/iso:1

organism-sequence


PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse), mDEGS2/iso:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000022016 DEGS2/iso:1

"A sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R2F2-1 or a 1:1 ortholog thereof." [PMID:11937514, PRO:HJD]		 acts_upstream_of_or_withinGO:0006667 sphinganine metabolic process MGI:3694278; PMID:16571104
GO:0046513 ceramide biosynthetic process MGI:3694278; PMID:16571104
enablesGO:0000170 sphingosine hydroxylase activity MGI:3694278; PMID:16571104
GO:0000170 sphingosine hydroxylase activity MGI:3694278; PMID:16571104
PR:Q8R2F2-1 mDEGS2/iso:1

"A sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]		 acts_upstream_of_or_withinGO:0006667 sphinganine metabolic process MGI:3694278; PMID:16571104
GO:0046513 ceramide biosynthetic process MGI:3694278; PMID:16571104
enablesGO:0000170 sphingosine hydroxylase activity MGI:3056825; PMID:15474011
GO:0000170 sphingosine hydroxylase activity MGI:3056825; PMID:15474011