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Protein Ontology report - Rho-associated protein kinase 1 proteolytic cleavage product
PR:000025435 - http://purl.obolibrary.org/obo/PR_000025435
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000025435   
  PRO nameRho-associated protein kinase 1 proteolytic cleavage product 
  Synonyms
PRO-Short-label: EXACT:ROCK1/ClvPrd
  Definition"A Rho-associated protein kinase 1 that has been processed by proteolytic cleavage." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000000120 Rho-associated protein kinase 1
PR:000018264 proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000025435 Rho-associated protein kinase 1 proteolytic cleavage product, ROCK1/ClvPrd

modification


PR:000000563 Rho-associated protein kinase 1 isoform 1 cleaved 1, ROCK1/iso:1/Clv:1

organism-modification


PR:000026340 Rho-associated protein kinase 1 isoform 1 cleaved 1 (human), hROCK1/iso:1/Clv:1
Yes
organism-modification


PR:000036476 Rho-associated protein kinase 1 isoform 1 cleaved 1 (mouse), mROCK1/iso:1/Clv:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026340 hROCK1/iso:1/Clv:1
UniProtKB:Q13464-1, 1-1113
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in human. UniProtKB:Q13464-1, 1-1113." [PRO:DNx, UniProtKB:Q13464]		 acts_upstream_of_or_withinGO:0006468 protein phosphorylation PMID:11283607
enablesincreased GO:0004674 protein serine/threonine kinase activity relative to PR:000002529 ROCK1/iso:1/UnMod PMID:11283607
PR:000036476 mROCK1/iso:1/Clv:1
UniProtKB:P70335-1, 1-1113
"A Rho-associated protein kinase 1 isoform 1 cleaved 1 in mouse. UniProtKB:P70335-1, 1-1113." [PMID:11283607, PMID:16983089, PRO:CNA]		 acts_upstream_of_or_withinGO:0010659 cardiac muscle cell apoptotic process PMID:16983089
GO:0030036 actin cytoskeleton organization PMID:11283607; PMID:16983089