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RACE-PRO
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Documentation
Protein Ontology report - lipopolysaccharide receptor complex 3
PR:000025497 -
http://purl.obolibrary.org/obo/PR_000025497
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000025497
PRO name
lipopolysaccharide receptor complex 3
Synonyms
PRO-Short-label
:
EXACT:
LPSR:3
Definition
"A lipopolysaccharide receptor complex that contains the membrane bound form of CD14, and the lipopolysaccharide (LPS) bound to LY96(MD-2)." [
PMID:7539760
,
PMID:9464818
]
PRO Category
complex
Parent
G0046696
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
1
Organism-Complex
4
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
complex
PR:000025497
lipopolysaccharide receptor complex 3, LPSR:3
organism-complex
PR:000025773
lipopolysaccharide receptor complex 3 (human), h(LPSR:3)
Yes
organism-complex
PR:000036136
lipopolysaccharide receptor complex 3; plasma membrane (human), h(LPSR:3)pm
Yes
organism-complex
PR:000036137
lipopolysaccharide receptor complex 3; endosome membrane (human), h(LPSR:3)endosome
Yes
organism-complex
PR:000037476
lipopolysaccharide receptor complex 3 (mouse), m(LPSR:3)
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000025773
h(LPSR:3)
TLR4:MD2:LPS:CD14 (human) (BROAD)
acts_upstream_of_or_within
GO:0034142
toll-like receptor 4 signaling pathway
Reactome:REACT_6894
PR:000036136
h(LPSR:3)pm
TLR4:MD2:LPS:CD14 [plasma membrane] (human)
acts_upstream_of_or_within
GO:0002755
MyD88-dependent toll-like receptor signaling pathway
Reactome:REACT_6894
located_in
GO:0005886
plasma membrane
Reactome:REACT_6894
PR:000036137
h(LPSR:3)endosome
TLR4:MD2:LPS:CD14 [endosome membrane] (human)
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6809
located_in
GO:0010008
endosome membrane
Reactome:REACT_6894
PR:000037476
m(LPSR:3)
TLR4:MD2:LPS:CD14 (mouse) (BROAD)
acts_upstream_of_or_within
GO:0034142
toll-like receptor 4 signaling pathway
PMID:12196527