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Protein Ontology report - smad2-smad4 protein complex 1

PR:000025967 - http://purl.obolibrary.org/obo/PR_000025967

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000025967

PRO name

smad2-smad4 protein complex 1

Synonyms

PRO-Short-label:

EXACT:

(SMAD2:SMAD4):1

Definition

"A smad2-smad4 protein complex that contains smad4 and the long isoform of smad2 phosphorylated in the last two Ser residues within the SSxS C-terminal motif." [PMID:15350224]

PRO Category

complex

Parent

G0071144

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Complex	1	Organism-Complex	2

Term Hierarchy
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DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

complex

PR:000025967 smad2-smad4 protein complex 1, (SMAD2:SMAD4):1

organism-complex

PR:000025933 smad2-smad4 protein complex 1 (human), h(pSMAD2:SMAD4):1

Yes

organism-complex

PR:000025944 smad2-smad4 protein complex 1 (mouse), m(SMAD2:SMAD4):1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000025933 h(pSMAD2:SMAD4):1	acts_upstream_of_or_within	GO:0007179 transforming growth factor beta receptor signaling pathway	PMID:8752209; PMID:8980228
	located_in	GO:0005654 nucleoplasm	Reactome:REACT_7382
	located_in	GO:0005829 cytosol	Reactome:REACT_7344
PR:000025944 m(SMAD2:SMAD4):1	acts_upstream_of_or_within	GO:0007179 transforming growth factor beta receptor signaling pathway	PMID:12672795
PR:000025944 m(SMAD2:SMAD4):1	located_in	GO:0005634 nucleus	PMID:12672795