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Protein Ontology report - IRAK4:MYD88:TIRAP:activated TLR4 complex
PR:000027182 - http://purl.obolibrary.org/obo/PR_000027182
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027182   
  PRO nameIRAK4:MYD88:TIRAP:activated TLR4 complex 
  Synonyms
Other: EXACT:IRAK4:MyD88:Mal:activated TLR4
  Definition"An IRAK4:MYD88:TIRAP:activated TLR complex that contains activated TLR4 receptor." [PMID:12297423, PRO:CNA, PRO:DAN, TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentPR:000027193 IRAK4:MYD88:TIRAP:activated TLR complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex, mIRAK4/UnMod

organism-complex


PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human), mIRAK4/UnMod
Yes
organism-complex


PR:000027187 IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse), TIRAP/iso:1

organism-complex


PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human), hIRAK4/iso:1/Phos:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027183 mIRAK4/UnMod
IRAK4:MyD88:Mal:activated TLR4 (human)
"An IRAK4:MYD88:TIRAP:activated TLR4 complex in human that is composed of activated TLR4 receptor, the long isoform of MyD88, Tirap/Mal, and IRAK4." [PMID:12297423, PRO:CNA]		 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
PR:000027192 hIRAK4/iso:1/Phos:1
pIRAK4:MyD88:Mal:activated TLR4 (human)
"An IRAK4:MYD88:TIRAP:activated TLR4 complex in human that is composed of activated TLR4 receptor, MyD88, Tirap/Mal, and phosphorylated IRAK4." [PMID:17141195, PRO:CNA]		 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894