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Protein Ontology report - cellular tumor antigen p53 isoform 1 acetylated 1
PR:000027773 -
http://purl.obolibrary.org/obo/PR_000027773
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000027773
PRO name
cellular tumor antigen p53 isoform 1 acetylated 1
Synonyms
PRO-Short-label
:
EXACT:
TP53/iso:1/Ac:1
Definition
"A cellular tumor antigen p53 isoform 1 that has been acetylated on a Lys residue within the DNA binding domain (
Pfam:PF00870
) in response to genotoxic stress. Example:
UniProtKB:P04637-1
, Lys-120,
MOD:00064
." [
PMID:17189187
, PRO:PD]
PRO Category
modification
Parent
PR:000003036
cellular tumor antigen p53 isoform 1
PR:000037073
acetylated protein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000027773
cellular tumor antigen p53 isoform 1 acetylated 1, TP53/iso:1/Ac:1
organism-modification
PR:000027774
cellular tumor antigen p53 isoform 1 acetylated 1 (human), hTP53/iso:1/Ac:1
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027774
hTP53/iso:1/Ac:1
UniProtKB:P04637-1, Lys-120, MOD:00064 | p53-acLys120
"A cellular tumor antigen p53 isoform 1 acetylated 1 in human. UniProtKB:P04637-1, Lys-120, MOD:00064." [PMID:17189187, PRO:PD]
acts_upstream_of_or_within
GO:0043065
positive regulation of apoptotic process
PMID:17189187
