back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - activated TLR4 complex
PR:000036076 - http://purl.obolibrary.org/obo/PR_000036076
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036076   
  PRO nameactivated TLR4 complex 
  Synonyms
PRO-Short-label: EXACT:TLR4actv
Other: EXACT:LY96:LPS:TLR4 complex | MD2:LPS:TLR4 complex | TLR4MD2LPS complex
  Definition"A protein-containing complex that contains TLR4, LPS and MD2(LY96)." [PMID:19252480, PRO:DAN, Reactome:R-HSA-166041, TLR:AMM] 
  CommentRequested by=TLR. Based on the crystal structure, known points of disulfide bonding, and other information, it is likely that the protein components correspond to PR:000003299 and PR:000025492. [PRO:DAN]. 
  PRO Categorycomplex 
  ParentG0043235
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000036076 activated TLR4 complex, TLR4actv

organism-complex


PR:000036077 activated TLR4 complex (mouse), mTLR4actv
Yes
organism-complex


PR:000037474 activated TLR4 complex (chicken), chick-TLR4actv
Yes
organism-complex


PR:000044684 activated TLR4 complex (human), hTLR4actv

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036077
mTLR4actv
LY96:LPS:TLR4 complex (mouse) | MD2:LPS:TLR4 complex (mouse) | TLR4MD2LPS complex dimer (mouse)		 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:23565187
PR:000037474
chick-TLR4actv
chick-(LY96:LPS:TLR4) | LY96:LPS:TLR4 complex (chicken) | MD2:LPS:TLR4 (chicken)		 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway PMID:18768894
GO:0045429 positive regulation of nitric oxide biosynthetic process PMID:24034933
GO:0051607 defense response to virus PMID:24034933
located_inGO:0005886 plasma membrane Reactome:REACT_25442