Home
|
Linked Open Data
|
Browse
|
Search
|
Statistics
|
Download
RACE-PRO
PRO tracker
Community
PRO Consortium
Publications
Documentation
Protein Ontology report - TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037447 -
http://purl.obolibrary.org/obo/PR_000037447
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000037447
PRO name
TIRAP:PIP2:BTK:activated TLR4 complex (human)
Synonyms
Other
:
EXACT:
MAL:PI(4,5)P2:BTK:activated TLR4 (human)
RELATED:
MAL:BTK:activated TLR4 (human)
Definition
"A TIRAP:PIP2:BTK:activated TLR4 complex in human that is composed of PI(4,5)P2, tyrosine unphosphorylated TIRAP/MAL, BTK, TLR4, MD2, CD14, LPS." [
PMID:11544529
,
PMID:12724322
,
PMID:12888566
,
Reactome:R
-HSA-2201331]
PRO Category
organism-complex
Parent
PR:000037472
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
Back to top
Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037447
FGF14/iso:3
MAL:PI(4,5)P2:BTK:activated TLR4 (human) | MAL:BTK:activated TLR4 (human)
acts_upstream_of_or_within
GO:0002755
MyD88-dependent toll-like receptor signaling pathway
Reactome:REACT_120882
GO:0034142
toll-like receptor 4 signaling pathway
Reactome:REACT_120882
enables
GO:0004713
protein tyrosine kinase activity
Reactome:REACT_120882
located_in
GO:0005886
plasma membrane
Reactome:REACT_120882