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Protein Ontology report - mitotic checkpoint protein BUB3 (human)
PR:O43684 - http://purl.obolibrary.org/obo/PR_O43684
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:O43684   
  PRO namemitotic checkpoint protein BUB3 (human) 
  Synonyms
PRO-Short-label: EXACT:hBUB3
Gene-based: RELATED:BUB3
  Definition"A mitotic checkpoint protein BUB3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43684] 
  PRO Categoryorganism-gene 
  ParentPR:000004856 mitotic checkpoint protein BUB3
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1151 BUB3 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 16                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O43684
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:O43684 mitotic checkpoint protein BUB3 (human), hBUB3
Yes
Yes
organism-sequence


PR:O43684-1 mitotic checkpoint protein BUB3 isoform h1 (human), hBUB3/iso:h1

organism-sequence


PR:O43684-2 mitotic checkpoint protein BUB3 isoform 2 (human), hBUB3/iso:2

organism-modification


PR:000035437 mitotic checkpoint protein BUB3 phosphorylated 1 (human), hBUB3/Phos:1
Yes
organism-modification


PR:000035454 mitotic checkpoint protein BUB3 unphosphorylated form (human), hBUB3/PhosRes-

organism-modification


PR:000045593 mitotic checkpoint protein BUB3 phosphorylated 2 (human), hBUB3/Phos:2

organism-modification


PR:000071531 mitotic checkpoint protein BUB3 methylated 1 (human), hBUB3/Me:1

organism-modification


PR:000071980 mitotic checkpoint protein BUB3 cysteinylated 1 (human), hBUB3/Cyst:1

organism-modification


PR:000072028 mitotic checkpoint protein BUB3 cysteinylated 2 (human), hBUB3/Cyst:2

organism-modification


PR:000072190 mitotic checkpoint protein BUB3 methylated 2 (human), hBUB3/Me:2

organism-modification


PR:000072404 mitotic checkpoint protein BUB3 acetylated 1 (human), hBUB3/Ac:1

organism-modification


PR:000073832 mitotic checkpoint protein BUB3 methylated 3 (human), hBUB3/Me:3

organism-modification


PR:000074693 mitotic checkpoint protein BUB3 cysteinylated 3 (human), hBUB3/Cyst:3

organism-modification


PR:000079964 mitotic checkpoint protein BUB3 deaminated 1 (human), hBUB3/Deam:1

organism-modification


PR:000083767 mitotic checkpoint protein BUB3 hydroxylated 1 (human), hBUB3/Hy:1

organism-modification


PR:000083783 mitotic checkpoint protein BUB3 methylated 4 (human), hBUB3/Me:4

organism-modification


PR:000083859 mitotic checkpoint protein BUB3 deaminated 2 (human), hBUB3/Deam:2

organism-modification


PR:000084196 mitotic checkpoint protein BUB3 deaminated 3 (human), hBUB3/Deam:3

organism-modification


PR:000085371 mitotic checkpoint protein BUB3 cysteinylated 4 (human), hBUB3/Cyst:4

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hBUB3 forms found in complexes   

hBUB3 Component
 Complexes
PR:O43684 hBUB3 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human)
PR:000035563 BUB1B:BUB3 complex (human)
PR:000035564 BUB1:BUB3 complex (human)
PR:000035567 BUB1:BUB3:MAD1L1 complex (human)
PR:000035576 BUB1:BUB3:APC complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035437 hBUB3/Phos:1
UniProtKB:O43684, Ser-18, MOD:00046
"A mitotic checkpoint protein BUB3 phosphorylated 1 in human. Phosphorylated on the Ser residue within the motif D[YG]ISx[IV]K. UniProtKB:O43684, Ser-18, MOD:00046." [PMID:20057499, PRO:DAN, PRO:KER]		 acts_upstream_of_or_withinincreased GO:0012501 programmed cell death relative to PR:000035454 hBUB3/PhosRes- PMID:20057499
PR:O43684 hBUB3
BUB3
"A mitotic checkpoint protein BUB3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43684]		 enablesGO:0005515 protein binding with PR:O15350-1 PMID:10198256
GO:0005515 protein binding with PR:O15350-2 PMID:10198256
GO:0005515 protein binding with PR:O15350-3 PMID:10198256
GO:0005515 protein binding with PR:O15350-5 PMID:10198256
GO:0005515 protein binding with PR:O43683 BUB1 PMID:10198256
GO:0005515 protein binding with PR:O60566 BUB1B PMID:10198256
GO:0005515 protein binding with PR:P25054 APC PMID:10198256
GO:0005515 protein binding with PR:Q12834 CDC20 PMID:10198256
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:10198256
GO:0005515 protein binding with PR:Q9Y6D9 hMAD1 PMID:10198256
located_inGO:0000776 kinetochore PMID:11283619