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Protein Ontology report - thrombospondin-1 (human)
PR:P07996 - http://purl.obolibrary.org/obo/PR_P07996
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P07996   
  PRO namethrombospondin-1 (human) 
  Synonyms
PRO-Short-label: EXACT:hTHBS1
Gene-based: RELATED:THBS1 | TSP | TSP1
Other: EXACT:glycoprotein G (human)
  Definition"A thrombospondin-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07996] 
  PRO Categoryorganism-gene 
  ParentPR:000000129 thrombospondin-1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:11785 THBS1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 16                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P07996
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P07996 thrombospondin-1 (human), hTHBS1

organism-sequence


PR:P07996-1 thrombospondin-1 isoform 1 (human), hTHBS1/iso:1

organism-modification


PR:000026338 thrombospondin-1 isoform 1, signal peptide removed form (human), hTHBS1/iso:1/SigPep-
Yes
organism-modification


PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human), hTHBS1/iso:1/SigPep-/Glyco:1
Yes
organism-modification


PR:000036489 thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human), hTHBS1/iso:1/Clv:2/Glyco:1

organism-modification


PR:000028966 thrombospondin-1 isoform 1 cleaved 2 (human), hTHBS1/iso:1/Clv:2

organism-sequence


PR:P07996-2 thrombospondin-1 isoform 2 (human), hTHBS1/iso:2

organism-modification


PR:000028410 thrombospondin-1, signal peptide removed form (human), hTHBS1/SigPep-
Yes
Yes
organism-modification


PR:000026338 thrombospondin-1 isoform 1, signal peptide removed form (human), hTHBS1/iso:1/SigPep-
Yes
organism-modification


PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human), hTHBS1/iso:1/SigPep-/Glyco:1
Yes
organism-modification


PR:000036489 thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human), hTHBS1/iso:1/Clv:2/Glyco:1

organism-modification


PR:000054414 thrombospondin-1 N-glycosylated 1 (human), hTHBS1/NGlyco:1

organism-modification


PR:000054415 thrombospondin-1 N-glycosylated 2 (human), hTHBS1/NGlyco:2

organism-modification


PR:000054416 thrombospondin-1 N-glycosylated 3 (human), hTHBS1/NGlyco:3

organism-modification


PR:000054418 thrombospondin-1 N-glycosylated 5 (human), hTHBS1/NGlyco:5

organism-modification


PR:000054419 thrombospondin-1 N-glycosylated 6 (human), hTHBS1/NGlyco:6

organism-modification


PR:000060409 thrombospondin-1, signal peptide removed fucosylserine form (human), hTHBS1/SigPep-/FucSer+

organism-modification


PR:000064777 thrombospondin-1, signal peptide removed O-glycosylserine form (human), hTHBS1/SigPep-/OGlycoSer+

organism-modification


PR:000073784 thrombospondin-1 methylated 1 (human), hTHBS1/Me:1

organism-modification


PR:000076437 thrombospondin-1 deaminated 1 (human), hTHBS1/Deam:1

organism-modification


PR:000079618 thrombospondin-1 cysteinylated 1 (human), hTHBS1/Cyst:1

organism-modification


PR:000079709 thrombospondin-1 cysteinylated 2 (human), hTHBS1/Cyst:2

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hTHBS1 forms found in complexes   

hTHBS1 Component
 Complexes
PR:000028410 hTHBS1/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026338 hTHBS1/iso:1/SigPep-
UniProtKB:P07996-1, 19-1170 | PRO_0000035842
"A thrombospondin-1 isoform 1, signal peptide removed form in human. UniProtKB:P07996-1, 19-1170." [PRO:DNx, UniProtKB:P07996]		 enablesGO:0004866 endopeptidase inhibitor activity PMID:8751720
located_inGO:0005615 extracellular space PMID:15662972
PR:000028410 hTHBS1/SigPep-
UniProtKB:P07996, 19-1170 | UniProtKB:P07996-1, 19-1170 | PRO_0000035842
"A thrombospondin-1, signal peptide removed form in human. Example: UniProtKB:P07996-1, 19-1170." [PRO:DNx]		 located_inGO:0005615 extracellular space PMID:15662972
PR:000036488 hTHBS1/iso:1/SigPep-/Glyco:1
UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813 | PRO_0000035842, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813
"A thrombospondin-1 isoform 1, signal peptide removed glycosylated form that is in human and has been post-translationally modified at four Trp residues, one Ser residue, and two Thr residues. UniProtKB:P07996-1, 19-1170, Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813." [PMID:11067851, PMID:12450399, PMID:15342643, PMID:3305519, PRO:CNA]		 enablesGO:0005515 protein binding with PR:000028966 hTHBS1/iso:1/Clv:2 PMID:3305519
GO:0050431 transforming growth factor beta binding PMID:15342643