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Protein Ontology report - vascular endothelial growth factor A, long form isoform 2 (mouse)
PR:Q00731-2 -
http://purl.obolibrary.org/obo/PR_Q00731-2
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:Q00731-2
PRO name
vascular endothelial growth factor A, long form isoform 2 (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mVEGFA/iso:2
Other
:
EXACT:
VEGF-1 (mouse) | VEGF164 (mouse)
Definition
"A vascular endothelial growth factor A, long form isoform 2 that is encoded in the genome of mouse." [
PMID:8614412
, PRO:KRC]
Comment
Note: RT-PCR evidence for transcript (Fig 2) and both immunoprecipitation and Western evidence for protein (Fig 4) in
PMID:8614412
.
PRO Category
organism-sequence
Parent
PR:000037370
vascular endothelial growth factor A, long form isoform 2
PR:Q00731
vascular endothelial growth factor A, long form (mouse)
Taxon
NCBITaxon:10090
Mus musculus
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q00731-2
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:Q00731-2
mVEGFA/iso:2
VEGF-1 (mouse) | VEGF164 (mouse)
"A vascular endothelial growth factor A, long form isoform 2 that is encoded in the genome of mouse." [PMID:8614412, PRO:KRC]
acts_upstream_of_or_within
GO:0001525
angiogenesis
MGI:3758404
;
PMID:17626017
GO:0001569
branching involved in blood vessel morphogenesis
MGI:3710026
;
PMID:17428830
GO:0001938
positive regulation of endothelial cell proliferation
MGI:74931
;
PMID:1592003
GO:0002053
positive regulation of mesenchymal cell proliferation
MGI:3613102
;
PMID:16375885
GO:0030324
lung development
MGI:3613102
;
PMID:16375885
GO:0048010
vascular endothelial growth factor receptor signaling pathway
MGI:74931
;
PMID:1592003
GO:0048754
branching morphogenesis of an epithelial tube
MGI:3613102
;
PMID:16375885
GO:0060426
lung vasculature development
MGI:1927039
;
PMID:11066091
enables
GO:0005102
signaling receptor binding
MGI:3758404
;
PMID:17626017
GO:0005515
protein binding
MGI:1860784
;
PMID:10705382
GO:0008201
heparin binding
MGI:77585
;
PMID:8614412
GO:0008201
heparin binding
MGI:77585
;
PMID:8614412
GO:0043183
vascular endothelial growth factor receptor 1 binding
MGI:3758404
;
PMID:17626017
GO:0043184
vascular endothelial growth factor receptor 2 binding
MGI:1860784
;
PMID:10705382
GO:0043184
vascular endothelial growth factor receptor 2 binding
MGI:1860784
;
PMID:10705382
GO:0050840
extracellular matrix binding
MGI:3758404
;
PMID:17626017
located_in
GO:0005576
extracellular region
MGI:77585
;
PMID:8614412