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Protein Ontology report - endonuclease 8-like 2 (human)
PR:Q969S2 -
http://purl.obolibrary.org/obo/PR_Q969S2
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:Q969S2
PRO name
endonuclease 8-like 2 (human)
Synonyms
PRO-Short-label
:
EXACT:
hNEIL2
Gene-based
:
RELATED:
NEIL2
Other
:
EXACT:
DNA glycosylase/AP lyase Neil2 (human) | DNA-(apurinic or apyrimidinic site) lyase Neil2 (human) | endonuclease VIII-like 2 (human) | NEH2 (human) | Nei homolog 2 (human) | Nei-like protein 2 (human)
Definition
"An endonuclease 8-like 2 that is encoded in the genome of human." [PRO:DNx,
UniProtKB:Q969S2
]
PRO Category
organism-gene
Parent
PR:000011123
endonuclease 8-like 2
PR:000029067
Homo sapiens protein
Gene Template
HGNC:18956
NEIL2 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
4
Modification
0
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:Q969S2
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:Q969S2
endonuclease 8-like 2 (human), hNEIL2
organism-sequence
PR:Q969S2-1
endonuclease 8-like 2 isoform 1 (human), hNEIL2/iso:1
organism-modification
PR:000028592
endonuclease 8-like 2 isoform 1, initiator methionine removed acetylated 1 (human), hNEIL2/iso:1/InitMet-/Ac:1
Yes
organism-modification
PR:000045372
endonuclease 8-like 2 isoform 1 unacetylated 1 (human), hNEIL2/iso:1/UnAc:1
Yes
organism-sequence
PR:Q969S2-2
endonuclease 8-like 2 isoform h2 (human), hNEIL2/iso:h2
organism-sequence
PR:Q969S2-3
endonuclease 8-like 2 isoform h3 (human), hNEIL2/iso:h3
organism-sequence
PR:Q969S2-4
endonuclease 8-like 2 isoform h4 (human), hNEIL2/iso:h4
organism-modification
PR:000048574
endonuclease 8-like 2, initiator methionine removed form (human), hNEIL2/InitMet-
organism-modification
PR:000028592
endonuclease 8-like 2 isoform 1, initiator methionine removed acetylated 1 (human), hNEIL2/iso:1/InitMet-/Ac:1
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000028592
hNEIL2/iso:1/InitMet-/Ac:1
UniProtKB:Q969S2-1, 2-331, Lys-50/Lys-154, MOD:00064 | NEIL2 acetylated (human)
"An endonuclease 8-like 2 isoform 1, initiator methionine removed acetylated 1 in human. UniProtKB:Q969S2-1, 2-331, Lys-50/Lys-154, MOD:00064." [KAT:Q969S2, PMID:15175427, PRO:PD]
enables
decreased
GO:0019104
DNA N-glycosylase activity
relative to
PR:000045372
endonuclease 8-like 2 isoform 1 unmodified form (human)
PMID:15175427
PR:000045372
hNEIL2/iso:1/UnAc:1
UniProtKB:Q969S2-1, 2-331, Lys-50/Lys-154, PR:000026291 | endonuclease 8-like 2 isoform 1 unmodified form (human)
"An endonuclease 8-like 2 isoform 1 (human) that lacks acetylation on Lys-50 and Lys-154. UniProtKB:Q969S2-1, 2-331, Lys-50/Lys-154, PR:000026291." [PMID:15175427, PRO:CNA]
enables
GO:0019104
DNA N-glycosylase activity
PMID:15175427