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Protein Ontology report - smad2 isoform Short phosphorylated 1
PR:000000656 - http://purl.obolibrary.org/obo/PR_000000656
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000656   
  PRO namesmad2 isoform Short phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:SMAD2/iso:Short/Phos:1
Other: RELATED:TGF-beta receptor-activated smad2
  Definition"A smad2 isoform Short phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation. Example: UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046." [PMID:15630024, PMID:17074756, PMID:9873005] 
  PRO Categorymodification 
  ParentPR:000000576
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000000656 smad2 isoform Short phosphorylated 1, SMAD2/iso:Short/Phos:1

Yes
organism-modification


PR:000025938 smad2 isoform Short phosphorylated 1 (human), hSMAD2/iso:Short/Phos:1
Yes
Yes
organism-modification


PR:000025943 smad2 isoform Short phosphorylated 1 (mouse), mSMAD2/iso:Short/Phos:1
Yes
Yes
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SMAD2/iso:Short/Phos:1 forms found in complexes   

SMAD2/iso:Short/Phos:1 Component
 Complexes
PR:000000656 SMAD2/iso:Short/Phos:1 PR:000025968
PR:000025938 hSMAD2/iso:Short/Phos:1 PR:000025940
PR:000025943 mSMAD2/iso:Short/Phos:1 PR:000025945
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025938
hSMAD2/iso:Short/Phos:1
UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:9873005
enablesGO:0003677 DNA binding PMID:14701940; PMID:9873005
GO:0003700 DNA-binding transcription factor activity PMID:9873005
GO:0003712 transcription coregulator activity PMID:14701940; PMID:9873005
PR:000025943
mSMAD2/iso:Short/Phos:1
UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046		 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:15630024
enablesGO:0003700 DNA-binding transcription factor activity PMID:15630024