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Protein Ontology report - vascular endothelial growth factor A, long form
PR:000017284 - http://purl.obolibrary.org/obo/PR_000017284
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000017284   
  PRO namevascular endothelial growth factor A, long form 
  Synonyms
PRO-Short-label: EXACT:VEGFA
Gene-based: RELATED:VEGF
Other: EXACT:L-VEGF | vascular endothelial growth factor A | vascular permeability factor | VEGF-A | VPF
  Definition"A protein that is a translation product of the human VEGFA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence3                                                  Organism-Sequence 30                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000017284 vascular endothelial growth factor A, long form, VEGFA

organism-gene


PR:O73682 vascular endothelial growth factor A-A (zebrafish), z-VEGFA

organism-sequence


PR:O73682-1 vascular endothelial growth factor A-A isoform VEGF165 (zebrafish), z-VEGFA/iso:VEGF165

organism-sequence


PR:O73682-2 vascular endothelial growth factor A-A isoform VEGF121 (zebrafish), z-VEGFA/iso:VEGF121

organism-gene


PR:P15692 vascular endothelial growth factor A, long form (human), hVEGFA

organism-sequence


PR:P15692-1 vascular endothelial growth factor A, long form isoform hVEGF206 (human), hVEGFA/iso:hVEGF206

organism-sequence


PR:P15692-10 vascular endothelial growth factor A, long form isoform hVEGF111 (human), hVEGFA/iso:hVEGF111

organism-sequence


PR:P15692-11 vascular endothelial growth factor A, long form isoform hL-VEGF165 (human), hVEGFA/iso:hL-VEGF165

organism-sequence


PR:P15692-12 vascular endothelial growth factor A, long form isoform hL-VEGF121 (human), hVEGFA/iso:hL-VEGF121

organism-sequence


PR:P15692-13 vascular endothelial growth factor A, long form isoform hL-VEGF189 (human), hVEGFA/iso:hL-VEGF189

organism-sequence


PR:P15692-14 vascular endothelial growth factor A, long form isoform hL-VEGF206 (human), hVEGFA/iso:hL-VEGF206

organism-sequence


PR:P15692-15 vascular endothelial growth factor A, long form isoform h15 (human), hVEGFA/iso:h15

organism-sequence


PR:P15692-16 vascular endothelial growth factor A, long form isoform h16 (human), hVEGFA/iso:h16

organism-sequence


PR:P15692-17 vascular endothelial growth factor A, long form isoform h17 (human), hVEGFA/iso:h17

organism-sequence


PR:P15692-18 vascular endothelial growth factor A, long form isoform h18 (human), hVEGFA/iso:h18

organism-sequence


PR:P15692-2 vascular endothelial growth factor A, long form isoform hVEGF189 (human), hVEGFA/iso:hVEGF189

organism-sequence


PR:P15692-3 vascular endothelial growth factor A, long form isoform hVEGF183 (human), hVEGFA/iso:hVEGF183

organism-sequence


PR:P15692-4 vascular endothelial growth factor A, long form isoform VEGF165 (human), hVEGFA/iso:VEGF165

organism-sequence


PR:P15692-5 vascular endothelial growth factor A, long form isoform hVEGF148 (human), hVEGFA/iso:hVEGF148

organism-sequence


PR:P15692-6 vascular endothelial growth factor A, long form isoform hVEGF145 (human), hVEGFA/iso:hVEGF145

organism-sequence


PR:P15692-8 vascular endothelial growth factor A, long form isoform hVEGF165B (human), hVEGFA/iso:hVEGF165B

organism-sequence


PR:P15692-9 vascular endothelial growth factor A, long form isoform hVEGF121 (human), hVEGFA/iso:hVEGF121

organism-modification


PR:000049655 vascular endothelial growth factor A, signal peptide removed form (human), hVEGFA/SigPep-

organism-gene


PR:P16612 vascular endothelial growth factor A (rat), rVEGFA

organism-sequence


PR:P16612-1 vascular endothelial growth factor A isoform 1 (rat), rVEGFA/iso:1

organism-sequence


PR:P16612-2 vascular endothelial growth factor A isoform 2 (rat), rVEGFA/iso:2

organism-sequence


PR:P16612-3 vascular endothelial growth factor A isoform rVEGF-A144 (rat), rVEGFA/iso:rVEGF-A144

organism-sequence


PR:P16612-4 vascular endothelial growth factor A isoform 3 (rat), rVEGFA/iso:3

organism-gene


PR:P67964 vascular endothelial growth factor A (chicken), chick-VEGFA

organism-gene


PR:Q00731 vascular endothelial growth factor A, long form (mouse), mVEGFA

organism-sequence


PR:Q00731-1 vascular endothelial growth factor A, long form isoform 1 (mouse), mVEGFA/iso:1

organism-sequence


PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse), mVEGFA/iso:2
Yes
organism-sequence


PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse), mVEGFA/iso:3
Yes
organism-sequence


PR:Q00731-4 vascular endothelial growth factor A, long form isoform 4 (mouse), mVEGFA/iso:4
Yes
organism-sequence


PR:Q00731-5 vascular endothelial growth factor A, long form isoform mVEGF-5 (mouse), mVEGFA/iso:mVEGF-5

organism-sequence


PR:Q00731-6 vascular endothelial growth factor A, long form isoform 6 (mouse), mVEGFA/iso:6

organism-sequence


PR:Q00731-7 vascular endothelial growth factor A, long form isoform mL-VEGF-2 (mouse), mVEGFA/iso:mL-VEGF-2

sequence


PR:000037369 vascular endothelial growth factor A, long form isoform 1, VEGFA/iso:1

organism-sequence


PR:P16612-1 vascular endothelial growth factor A isoform 1 (rat), rVEGFA/iso:1

organism-sequence


PR:Q00731-1 vascular endothelial growth factor A, long form isoform 1 (mouse), mVEGFA/iso:1

sequence


PR:000037370 vascular endothelial growth factor A, long form isoform 2, VEGFA/iso:2

organism-sequence


PR:P16612-2 vascular endothelial growth factor A isoform 2 (rat), rVEGFA/iso:2

organism-sequence


PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse), mVEGFA/iso:2
Yes
sequence


PR:000037371 vascular endothelial growth factor A, long form isoform 3, VEGFA/iso:3

organism-sequence


PR:P16612-4 vascular endothelial growth factor A isoform 3 (rat), rVEGFA/iso:3

organism-sequence


PR:Q00731-3 vascular endothelial growth factor A, long form isoform 3 (mouse), mVEGFA/iso:3
Yes
modification


PR:000021820 vascular endothelial growth factor A, long form, signal peptide removed form, VEGFA/SigPep-

organism-modification


PR:000049655 vascular endothelial growth factor A, signal peptide removed form (human), hVEGFA/SigPep-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q00731-2 mVEGFA/iso:2
VEGF-1 (mouse) | VEGF164 (mouse)
"A vascular endothelial growth factor A, long form isoform 2 that is encoded in the genome of mouse." [PMID:8614412, PRO:KRC]		 acts_upstream_of_or_withinGO:0001525 angiogenesis MGI:3758404; PMID:17626017
GO:0001569 branching involved in blood vessel morphogenesis MGI:3710026; PMID:17428830
GO:0001938 positive regulation of endothelial cell proliferation MGI:74931; PMID:1592003
GO:0002053 positive regulation of mesenchymal cell proliferation MGI:3613102; PMID:16375885
GO:0030324 lung development MGI:3613102; PMID:16375885
GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI:74931; PMID:1592003
GO:0048754 branching morphogenesis of an epithelial tube MGI:3613102; PMID:16375885
GO:0060426 lung vasculature development MGI:1927039; PMID:11066091
enablesGO:0005102 signaling receptor binding MGI:3758404; PMID:17626017
GO:0005515 protein binding MGI:1860784; PMID:10705382
GO:0008201 heparin binding MGI:77585; PMID:8614412
GO:0008201 heparin binding MGI:77585; PMID:8614412
GO:0043183 vascular endothelial growth factor receptor 1 binding MGI:3758404; PMID:17626017
GO:0043184 vascular endothelial growth factor receptor 2 binding MGI:1860784; PMID:10705382
GO:0043184 vascular endothelial growth factor receptor 2 binding MGI:1860784; PMID:10705382
GO:0050840 extracellular matrix binding MGI:3758404; PMID:17626017
located_inGO:0005576 extracellular region MGI:77585; PMID:8614412
PR:Q00731-3 mVEGFA/iso:3
VEGF-2 (mouse) | VEGF120 (mouse)
"A vascular endothelial growth factor A, long form isoform 3 that is encoded in the genome of mouse." [PMID:8614412, PRO:KRC]		 acts_upstream_of_or_withinGO:0001525 angiogenesis MGI:3758404; PMID:17626017
GO:0001938 positive regulation of endothelial cell proliferation MGI:74931; PMID:1592003
GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI:74931; PMID:1592003
located_inGO:0005576 extracellular region MGI:77585; PMID:8614412
GO:0005615 extracellular space MGI:74931; PMID:1592003
PR:Q00731-4 mVEGFA/iso:4
VEGF-4 (mouse) | VEGF115 (mouse)
"A vascular endothelial growth factor A, long form (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00731-4." [PMID:9446618, PRO:KRC]		 acts_upstream_of_or_withinGO:0001938 positive regulation of endothelial cell proliferation MGI:1195544; PMID:9446618
enablesGO:0008083 growth factor activity MGI:1195544; PMID:9446618
located_inGO:0005576 extracellular region MGI:1195544; PMID:9446618