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Protein Ontology report - pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human) PR:000036060 - http://purl.obolibrary.org/obo/PR_000036060        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000036060      PRO name pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)    Synonyms Other: EXACT: activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 (human)   Definition "A pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [Reactome:R-HSA-2562542]    Comment Requested by=TLR.    PRO Category organism-complex    Parent PR:000036059   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000036060 hRIPK1/K63polyUbiq:1 activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 (human) acts_upstream_of_or_within GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809 enables GO:0004197 cysteine-type endopeptidase activity Reactome:REACT_151344 located_in GO:0010008 endosome membrane Reactome:REACT_151344