Protein Ontology

Home

Linked Open Data

Browse

Statistics

Download

RACE-PRO

PRO tracker

Community

PRO Consortium

Publications

Documentation

Protein Ontology report - Bcl2-associated agonist of cell death (mouse)

PR:Q61337 - http://purl.obolibrary.org/obo/PR_Q61337

Protein Forms

Annotations

Ontology Information

Show OBO stanza

GPI

PRO ID

PR:Q61337

PRO name

Bcl2-associated agonist of cell death (mouse)

Synonyms

PRO-Short-label:	EXACT:	mBAD
Gene-based:	RELATED:	Bad \| Bbc6
Other:	EXACT:	BAD (mouse) \| Bcl-2-binding component 6 (mouse) \| Bcl-xL/Bcl-2-associated death promoter (mouse) \| Bcl2 antagonist of cell death (mouse)

Definition

"A Bcl2-associated agonist of cell death that is encoded in the genome of mouse." [OMA:Q61337, PRO:DNx]

PRO Category

organism-gene

Parent

PR:000002184
PR:000029032

Gene Template

MGI:1096330 Bad (mouse)

Taxon

NCBITaxon:10090 Mus musculus

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	0	Organism-Gene	1
Sequence	0	Organism-Sequence	2
Modification	0	Organism-Modification	9

Term Hierarchy
Visualization

DAG:

OLS:

Back to top

Related Cross References
Db identifiers	UniProtKB:Q61337

Back to top

Protein Forms

Switch to Extended View

Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

organism-gene

PR:Q61337 Bcl2-associated agonist of cell death (mouse), mBAD

organism-sequence

PR:Q3U9H3 Bcl2-associated agonist of cell death isoform 2 (mouse), mBAD/iso:2

organism-sequence

PR:Q61337-1 Bcl2-associated agonist of cell death isoform 1 (mouse), mBAD/iso:1

organism-modification

PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse), mBAD/iso:1/Phos:2

Yes

organism-modification

PR:000026135 Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse), mBAD/iso:1/Phos:4

Yes

organism-modification

PR:000026136 Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse), mBAD/iso:1/Phos:5

Yes

organism-modification

PR:000026137 Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse), mBAD/iso:1/Phos:6

Yes

organism-modification

PR:000026138 Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse), mBAD/iso:1/Phos:7

organism-modification

PR:000026139 Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse), mBAD/iso:1/Phos:8

Yes

organism-modification

PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse), mBAD/iso:1/Phos:1

Yes

organism-modification

PR:000037809 Bcl2-associated agonist of cell death isoform 1 unphosphorylated 1 (mouse), mBAD/iso:1/UnPhos:1

organism-modification

PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse), mBAD/iso:1/UnMod

Yes

Back to top

Functional Annotation (PRO-centric view)

Switch to GO Centric View

PRO Term	GO Annotation		Evidence
PR:000026133 mBAD/iso:1/Phos:2 UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046	acts_upstream_of_or_within	GO:0043066 negative regulation of apoptotic process	PMID:10949026
	enables	NOT GO:0005515 protein binding with PR:000003237 fam:14-3-3	PMID:10949026
		NOT GO:0005515 protein binding with PR:P63101-1	PMID:10949026
		NOT GO:0005515 protein binding with PR:Q64373-1	PMID:10949026
		NOT GO:0005515 protein binding with PR:Q07817-1	PMID:10949026
PR:000026135 mBAD/iso:1/Phos:4 UniProtKB:Q61337-1, Thr-201, MOD:00047	acts_upstream_of_or_within	GO:0043066 negative regulation of apoptotic process	PMID:14967141
	enables	decreased GO:0005515 protein binding with PR:Q64373-1	PMID:14967141
PR:000026136 mBAD/iso:1/Phos:5 UniProtKB:Q61337-1, Ser-136, MOD:00046	enables	GO:0005515 protein binding with PR:P63101 KCIP-1 (mouse)	PMID:12049737
PR:000026137 mBAD/iso:1/Phos:6 UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046	acts_upstream_of_or_within	GO:0051402 neuron apoptotic process	PMID:12049737
PR:000026139 mBAD/iso:1/Phos:8 UniProtKB:Q61337-1, Ser-155, MOD:00046	enables	GO:0071889 14-3-3 protein binding with PR:P61982 mYWHAG	PMID:10880354
PR:000026167 mBAD/iso:1/Phos:1 UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046	enables	decreased GO:0005515 protein binding with PR:P62258-1	PMID:12049737
		decreased GO:0005515 protein binding with PR:Q07817-1	PMID:12049737
		decreased GO:0005515 protein binding with PR:Q9CQV8 KCIP-1 (mouse)	PMID:12049737
		decreased GO:0005515 protein binding with PR:P63101 KCIP-1 (mouse)	PMID:12049737
PR:000044747 mBAD/iso:1/UnMod	acts_upstream_of_or_within	GO:0006915 apoptotic process	PMID:15280015
	enables	GO:0005515 protein binding with PR:P04049 cRaf (human)	PMID:17011751
		GO:0005515 protein binding with PR:P06803-2	PMID:17011751
		GO:0005515 protein binding with PR:P15056 BRAF	PMID:17011751
		GO:0005515 protein binding with PR:Q04759 hPRKCQ	PMID:17011751
	located_in	GO:0031966 mitochondrial membrane	PMID:15280015